-- dump date   	20140620_055650
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
990282000001	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
990282000002	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
990282000003	putative catalytic residues [active]
990282000004	putative nucleotide binding site [chemical binding]; other site
990282000005	putative aspartate binding site [chemical binding]; other site
990282000006	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
990282000007	dimer interface [polypeptide binding]; other site
990282000008	putative threonine allosteric regulatory site; other site
990282000009	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
990282000010	putative threonine allosteric regulatory site; other site
990282000011	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
990282000012	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
990282000013	homoserine kinase; Provisional; Region: PRK01212
990282000014	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
990282000015	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
990282000016	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
990282000017	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282000018	catalytic residue [active]
990282000019	hypothetical protein; Validated; Region: PRK02101
990282000020	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
990282000021	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
990282000022	transaldolase-like protein; Provisional; Region: PTZ00411
990282000023	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
990282000024	active site
990282000025	dimer interface [polypeptide binding]; other site
990282000026	catalytic residue [active]
990282000027	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
990282000028	MPT binding site; other site
990282000029	trimer interface [polypeptide binding]; other site
990282000030	hypothetical protein; Provisional; Region: PRK10659
990282000031	hypothetical protein; Provisional; Region: PRK10236
990282000032	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
990282000033	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
990282000034	Protein of unknown function (DUF2541); Region: DUF2541; pfam10807
990282000035	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
990282000036	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
990282000037	nucleotide binding site [chemical binding]; other site
990282000038	chaperone protein DnaJ; Provisional; Region: PRK10767
990282000039	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
990282000040	HSP70 interaction site [polypeptide binding]; other site
990282000041	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
990282000042	substrate binding site [polypeptide binding]; other site
990282000043	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
990282000044	Zn binding sites [ion binding]; other site
990282000045	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
990282000046	dimer interface [polypeptide binding]; other site
990282000047	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282000048	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282000049	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
990282000050	substrate binding pocket [chemical binding]; other site
990282000051	dimerization interface [polypeptide binding]; other site
990282000052	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
990282000053	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
990282000054	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
990282000055	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
990282000056	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
990282000057	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
990282000058	active site
990282000059	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
990282000060	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
990282000061	aromatic chitin/cellulose binding site residues [chemical binding]; other site
990282000062	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
990282000063	Helix-turn-helix domain; Region: HTH_36; pfam13730
990282000064	fimbrial protein BcfA; Provisional; Region: PRK15187
990282000065	fimbrial chaperone protein BcfB; Provisional; Region: PRK15188
990282000066	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
990282000067	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
990282000068	outer membrane usher protein; Provisional; Region: PRK15193
990282000069	PapC N-terminal domain; Region: PapC_N; pfam13954
990282000070	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
990282000071	PapC C-terminal domain; Region: PapC_C; pfam13953
990282000072	fimbrial protein BcfD; Provisional; Region: PRK15189
990282000073	fimbrial protein BcfE; Provisional; Region: PRK15190
990282000074	fimbrial protein BcfF; Provisional; Region: PRK15191
990282000075	fimbrial chaperone BcfG; Provisional; Region: PRK15192
990282000076	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
990282000077	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
990282000078	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
990282000079	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
990282000080	catalytic residues [active]
990282000081	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
990282000082	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282000083	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282000084	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
990282000085	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
990282000086	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
990282000087	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
990282000088	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
990282000089	active site
990282000090	metal binding site [ion binding]; metal-binding site
990282000091	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
990282000092	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; pfam03502
990282000093	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
990282000094	Sulfatase; Region: Sulfatase; pfam00884
990282000095	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
990282000096	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282000097	FeS/SAM binding site; other site
990282000098	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
990282000099	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
990282000100	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
990282000101	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
990282000102	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
990282000103	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282000104	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
990282000105	putative dimerization interface [polypeptide binding]; other site
990282000106	putative alpha-glucosidase; Provisional; Region: PRK10658
990282000107	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
990282000108	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
990282000109	putative active site [active]
990282000110	putative catalytic site [active]
990282000111	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
990282000112	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
990282000113	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
990282000114	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
990282000115	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
990282000116	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
990282000117	active site
990282000118	Riboflavin kinase; Region: Flavokinase; smart00904
990282000119	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
990282000120	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
990282000121	active site
990282000122	HIGH motif; other site
990282000123	nucleotide binding site [chemical binding]; other site
990282000124	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
990282000125	active site
990282000126	KMSKS motif; other site
990282000127	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
990282000128	tRNA binding surface [nucleotide binding]; other site
990282000129	anticodon binding site; other site
990282000130	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
990282000131	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
990282000132	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
990282000133	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
990282000134	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
990282000135	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
990282000136	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
990282000137	active site
990282000138	tetramer interface [polypeptide binding]; other site
990282000139	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
990282000140	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282000141	active site
990282000142	phosphorylation site [posttranslational modification]
990282000143	intermolecular recognition site; other site
990282000144	dimerization interface [polypeptide binding]; other site
990282000145	Transcriptional regulator; Region: CitT; pfam12431
990282000146	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
990282000147	PAS domain; Region: PAS; smart00091
990282000148	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282000149	ATP binding site [chemical binding]; other site
990282000150	Mg2+ binding site [ion binding]; other site
990282000151	G-X-G motif; other site
990282000152	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
990282000153	oxaloacetate decarboxylase; Provisional; Region: PRK14040
990282000154	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
990282000155	active site
990282000156	catalytic residues [active]
990282000157	metal binding site [ion binding]; metal-binding site
990282000158	homodimer binding site [polypeptide binding]; other site
990282000159	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
990282000160	carboxyltransferase (CT) interaction site; other site
990282000161	biotinylation site [posttranslational modification]; other site
990282000162	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
990282000163	Na+/citrate symporter [Energy production and conversion]; Region: CitS; COG3493
990282000164	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
990282000165	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
990282000166	putative active site [active]
990282000167	(T/H)XGH motif; other site
990282000168	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
990282000169	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
990282000170	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
990282000171	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
990282000172	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
990282000173	triphosphoribosyl-dephospho-CoA synthase CitG; Region: citrate_citG; TIGR03125
990282000174	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
990282000175	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
990282000176	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
990282000177	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
990282000178	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
990282000179	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
990282000180	catalytic site [active]
990282000181	subunit interface [polypeptide binding]; other site
990282000182	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
990282000183	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
990282000184	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
990282000185	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
990282000186	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
990282000187	ATP-grasp domain; Region: ATP-grasp_4; cl17255
990282000188	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
990282000189	IMP binding site; other site
990282000190	dimer interface [polypeptide binding]; other site
990282000191	interdomain contacts; other site
990282000192	partial ornithine binding site; other site
990282000193	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
990282000194	carnitine operon protein CaiE; Provisional; Region: PRK13627
990282000195	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
990282000196	putative trimer interface [polypeptide binding]; other site
990282000197	putative metal binding site [ion binding]; other site
990282000198	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
990282000199	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
990282000200	substrate binding site [chemical binding]; other site
990282000201	oxyanion hole (OAH) forming residues; other site
990282000202	trimer interface [polypeptide binding]; other site
990282000203	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
990282000204	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
990282000205	acyl-activating enzyme (AAE) consensus motif; other site
990282000206	putative AMP binding site [chemical binding]; other site
990282000207	putative active site [active]
990282000208	putative CoA binding site [chemical binding]; other site
990282000209	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
990282000210	CoA-transferase family III; Region: CoA_transf_3; pfam02515
990282000211	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
990282000212	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
990282000213	active site
990282000214	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
990282000215	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
990282000216	Ligand binding site [chemical binding]; other site
990282000217	Electron transfer flavoprotein domain; Region: ETF; pfam01012
990282000218	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
990282000219	Electron transfer flavoprotein domain; Region: ETF; smart00893
990282000220	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
990282000221	putative oxidoreductase FixC; Provisional; Region: PRK10157
990282000222	ferredoxin-like protein FixX; Provisional; Region: PRK15449
990282000223	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282000224	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
990282000225	putative substrate translocation pore; other site
990282000226	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
990282000227	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
990282000228	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
990282000229	Sulfatase; Region: Sulfatase; cl17466
990282000230	Sulfatase; Region: Sulfatase; cl17466
990282000231	Sulfatase; Region: Sulfatase; cl17466
990282000232	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
990282000233	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
990282000234	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
990282000235	TrkA-N domain; Region: TrkA_N; pfam02254
990282000236	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
990282000237	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
990282000238	folate binding site [chemical binding]; other site
990282000239	NADP+ binding site [chemical binding]; other site
990282000240	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
990282000241	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
990282000242	active site
990282000243	metal binding site [ion binding]; metal-binding site
990282000244	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
990282000245	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
990282000246	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
990282000247	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
990282000248	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
990282000249	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
990282000250	SurA N-terminal domain; Region: SurA_N; pfam09312
990282000251	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
990282000252	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
990282000253	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
990282000254	OstA-like protein; Region: OstA; pfam03968
990282000255	Organic solvent tolerance protein; Region: OstA_C; pfam04453
990282000256	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
990282000257	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
990282000258	putative metal binding site [ion binding]; other site
990282000259	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
990282000260	HSP70 interaction site [polypeptide binding]; other site
990282000261	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
990282000262	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
990282000263	active site
990282000264	ATP-dependent helicase HepA; Validated; Region: PRK04914
990282000265	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
990282000266	ATP binding site [chemical binding]; other site
990282000267	putative Mg++ binding site [ion binding]; other site
990282000268	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
990282000269	nucleotide binding region [chemical binding]; other site
990282000270	ATP-binding site [chemical binding]; other site
990282000271	DNA polymerase II; Reviewed; Region: PRK05762
990282000272	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
990282000273	active site
990282000274	catalytic site [active]
990282000275	substrate binding site [chemical binding]; other site
990282000276	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
990282000277	active site
990282000278	metal-binding site
990282000279	Uncharacterized conserved protein [Function unknown]; Region: COG1434
990282000280	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
990282000281	putative active site [active]
990282000282	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
990282000283	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
990282000284	intersubunit interface [polypeptide binding]; other site
990282000285	active site
990282000286	Zn2+ binding site [ion binding]; other site
990282000287	L-arabinose isomerase; Provisional; Region: PRK02929
990282000288	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
990282000289	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
990282000290	trimer interface [polypeptide binding]; other site
990282000291	putative substrate binding site [chemical binding]; other site
990282000292	putative metal binding site [ion binding]; other site
990282000293	ribulokinase; Provisional; Region: PRK04123
990282000294	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
990282000295	N- and C-terminal domain interface [polypeptide binding]; other site
990282000296	active site
990282000297	MgATP binding site [chemical binding]; other site
990282000298	catalytic site [active]
990282000299	metal binding site [ion binding]; metal-binding site
990282000300	carbohydrate binding site [chemical binding]; other site
990282000301	homodimer interface [polypeptide binding]; other site
990282000302	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
990282000303	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
990282000304	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282000305	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282000306	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
990282000307	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
990282000308	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
990282000309	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
990282000310	Walker A/P-loop; other site
990282000311	ATP binding site [chemical binding]; other site
990282000312	Q-loop/lid; other site
990282000313	ABC transporter signature motif; other site
990282000314	Walker B; other site
990282000315	D-loop; other site
990282000316	H-loop/switch region; other site
990282000317	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
990282000318	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282000319	dimer interface [polypeptide binding]; other site
990282000320	conserved gate region; other site
990282000321	putative PBP binding loops; other site
990282000322	ABC-ATPase subunit interface; other site
990282000323	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282000324	dimer interface [polypeptide binding]; other site
990282000325	conserved gate region; other site
990282000326	putative PBP binding loops; other site
990282000327	ABC-ATPase subunit interface; other site
990282000328	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
990282000329	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
990282000330	transcriptional regulator SgrR; Provisional; Region: PRK13626
990282000331	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
990282000332	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
990282000333	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
990282000334	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
990282000335	substrate binding site [chemical binding]; other site
990282000336	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
990282000337	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
990282000338	substrate binding site [chemical binding]; other site
990282000339	ligand binding site [chemical binding]; other site
990282000340	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
990282000341	tartrate dehydrogenase; Region: TTC; TIGR02089
990282000342	2-isopropylmalate synthase; Validated; Region: PRK00915
990282000343	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
990282000344	active site
990282000345	catalytic residues [active]
990282000346	metal binding site [ion binding]; metal-binding site
990282000347	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
990282000348	leu operon leader peptide; Provisional; Region: PRK14744
990282000349	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
990282000350	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282000351	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
990282000352	putative substrate binding pocket [chemical binding]; other site
990282000353	putative dimerization interface [polypeptide binding]; other site
990282000354	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
990282000355	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
990282000356	dimer interface [polypeptide binding]; other site
990282000357	PYR/PP interface [polypeptide binding]; other site
990282000358	TPP binding site [chemical binding]; other site
990282000359	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
990282000360	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
990282000361	TPP-binding site [chemical binding]; other site
990282000362	dimer interface [polypeptide binding]; other site
990282000363	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
990282000364	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
990282000365	putative valine binding site [chemical binding]; other site
990282000366	dimer interface [polypeptide binding]; other site
990282000367	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
990282000368	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
990282000369	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
990282000370	DNA binding site [nucleotide binding]
990282000371	domain linker motif; other site
990282000372	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
990282000373	dimerization interface [polypeptide binding]; other site
990282000374	ligand binding site [chemical binding]; other site
990282000375	mraZ protein; Region: TIGR00242
990282000376	MraZ protein; Region: MraZ; pfam02381
990282000377	MraZ protein; Region: MraZ; pfam02381
990282000378	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
990282000379	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
990282000380	cell division protein FtsL; Provisional; Region: PRK10772
990282000381	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
990282000382	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
990282000383	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
990282000384	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
990282000385	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
990282000386	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
990282000387	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
990282000388	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
990282000389	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
990282000390	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
990282000391	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
990282000392	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
990282000393	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
990282000394	Mg++ binding site [ion binding]; other site
990282000395	putative catalytic motif [active]
990282000396	putative substrate binding site [chemical binding]; other site
990282000397	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
990282000398	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
990282000399	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
990282000400	cell division protein FtsW; Provisional; Region: PRK10774
990282000401	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
990282000402	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
990282000403	active site
990282000404	homodimer interface [polypeptide binding]; other site
990282000405	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
990282000406	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
990282000407	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
990282000408	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
990282000409	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
990282000410	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
990282000411	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
990282000412	cell division protein FtsQ; Provisional; Region: PRK10775
990282000413	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
990282000414	Cell division protein FtsQ; Region: FtsQ; pfam03799
990282000415	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
990282000416	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
990282000417	Cell division protein FtsA; Region: FtsA; pfam14450
990282000418	cell division protein FtsZ; Validated; Region: PRK09330
990282000419	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
990282000420	nucleotide binding site [chemical binding]; other site
990282000421	SulA interaction site; other site
990282000422	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
990282000423	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
990282000424	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
990282000425	SecA regulator SecM; Provisional; Region: PRK02943
990282000426	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
990282000427	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
990282000428	SEC-C motif; Region: SEC-C; pfam02810
990282000429	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
990282000430	active site
990282000431	8-oxo-dGMP binding site [chemical binding]; other site
990282000432	nudix motif; other site
990282000433	metal binding site [ion binding]; metal-binding site
990282000434	DNA gyrase inhibitor; Reviewed; Region: PRK00418
990282000435	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
990282000436	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
990282000437	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
990282000438	CoA-binding site [chemical binding]; other site
990282000439	ATP-binding [chemical binding]; other site
990282000440	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
990282000441	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
990282000442	active site
990282000443	type IV pilin biogenesis protein; Provisional; Region: PRK10573
990282000444	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
990282000445	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
990282000446	hypothetical protein; Provisional; Region: PRK10436
990282000447	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
990282000448	Walker A motif; other site
990282000449	ATP binding site [chemical binding]; other site
990282000450	Walker B motif; other site
990282000451	putative major pilin subunit; Provisional; Region: PRK10574
990282000452	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
990282000453	Pilin (bacterial filament); Region: Pilin; pfam00114
990282000454	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
990282000455	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
990282000456	dimerization interface [polypeptide binding]; other site
990282000457	active site
990282000458	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
990282000459	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
990282000460	amidase catalytic site [active]
990282000461	Zn binding residues [ion binding]; other site
990282000462	substrate binding site [chemical binding]; other site
990282000463	regulatory protein AmpE; Provisional; Region: PRK10987
990282000464	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
990282000465	active site
990282000466	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
990282000467	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282000468	putative substrate translocation pore; other site
990282000469	aromatic amino acid transporter; Provisional; Region: PRK10238
990282000470	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
990282000471	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282000472	DNA-binding site [nucleotide binding]; DNA binding site
990282000473	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
990282000474	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
990282000475	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
990282000476	dimer interface [polypeptide binding]; other site
990282000477	TPP-binding site [chemical binding]; other site
990282000478	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
990282000479	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
990282000480	E3 interaction surface; other site
990282000481	lipoyl attachment site [posttranslational modification]; other site
990282000482	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
990282000483	E3 interaction surface; other site
990282000484	lipoyl attachment site [posttranslational modification]; other site
990282000485	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
990282000486	E3 interaction surface; other site
990282000487	lipoyl attachment site [posttranslational modification]; other site
990282000488	e3 binding domain; Region: E3_binding; pfam02817
990282000489	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
990282000490	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
990282000491	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
990282000492	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
990282000493	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
990282000494	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
990282000495	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
990282000496	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
990282000497	substrate binding site [chemical binding]; other site
990282000498	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
990282000499	substrate binding site [chemical binding]; other site
990282000500	ligand binding site [chemical binding]; other site
990282000501	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3183
990282000502	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
990282000503	hypothetical protein; Provisional; Region: PRK05248
990282000504	2-keto-3-deoxygluconate permease; Provisional; Region: PRK12460
990282000505	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
990282000506	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
990282000507	4-hydroxythreonine-4-phosphate dehydrogenase 2; Provisional; Region: pdxA; PRK03371
990282000508	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
990282000509	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
990282000510	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
990282000511	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
990282000512	spermidine synthase; Provisional; Region: PRK00811
990282000513	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282000514	S-adenosylmethionine binding site [chemical binding]; other site
990282000515	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
990282000516	multicopper oxidase; Provisional; Region: PRK10965
990282000517	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
990282000518	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
990282000519	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
990282000520	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
990282000521	Trp docking motif [polypeptide binding]; other site
990282000522	putative active site [active]
990282000523	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
990282000524	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
990282000525	active site
990282000526	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
990282000527	active site clefts [active]
990282000528	zinc binding site [ion binding]; other site
990282000529	dimer interface [polypeptide binding]; other site
990282000530	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
990282000531	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
990282000532	Walker A/P-loop; other site
990282000533	ATP binding site [chemical binding]; other site
990282000534	Q-loop/lid; other site
990282000535	ABC transporter signature motif; other site
990282000536	Walker B; other site
990282000537	D-loop; other site
990282000538	H-loop/switch region; other site
990282000539	inner membrane transport permease; Provisional; Region: PRK15066
990282000540	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
990282000541	putative fimbrial protein StiH; Provisional; Region: PRK15297
990282000542	fimbrial outer membrane usher protein StiC; Provisional; Region: PRK15298
990282000543	PapC N-terminal domain; Region: PapC_N; pfam13954
990282000544	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
990282000545	PapC C-terminal domain; Region: PapC_C; pfam13953
990282000546	fimbrial chaperone protein StiB; Provisional; Region: PRK15299
990282000547	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
990282000548	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
990282000549	fimbrial protein StiA; Provisional; Region: PRK15300
990282000550	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
990282000551	active pocket/dimerization site; other site
990282000552	active site
990282000553	phosphorylation site [posttranslational modification]
990282000554	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
990282000555	putative active site [active]
990282000556	putative metal binding site [ion binding]; other site
990282000557	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
990282000558	tetramerization interface [polypeptide binding]; other site
990282000559	active site
990282000560	Pantoate-beta-alanine ligase; Region: PanC; cd00560
990282000561	pantoate--beta-alanine ligase; Region: panC; TIGR00018
990282000562	active site
990282000563	ATP-binding site [chemical binding]; other site
990282000564	pantoate-binding site; other site
990282000565	HXXH motif; other site
990282000566	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
990282000567	oligomerization interface [polypeptide binding]; other site
990282000568	active site
990282000569	metal binding site [ion binding]; metal-binding site
990282000570	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
990282000571	catalytic center binding site [active]
990282000572	ATP binding site [chemical binding]; other site
990282000573	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
990282000574	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
990282000575	active site
990282000576	NTP binding site [chemical binding]; other site
990282000577	metal binding triad [ion binding]; metal-binding site
990282000578	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
990282000579	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
990282000580	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
990282000581	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
990282000582	active site
990282000583	nucleotide binding site [chemical binding]; other site
990282000584	HIGH motif; other site
990282000585	KMSKS motif; other site
990282000586	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
990282000587	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
990282000588	2'-5' RNA ligase; Provisional; Region: PRK15124
990282000589	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
990282000590	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
990282000591	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
990282000592	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
990282000593	ATP binding site [chemical binding]; other site
990282000594	putative Mg++ binding site [ion binding]; other site
990282000595	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
990282000596	nucleotide binding region [chemical binding]; other site
990282000597	ATP-binding site [chemical binding]; other site
990282000598	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
990282000599	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
990282000600	Transglycosylase; Region: Transgly; pfam00912
990282000601	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
990282000602	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
990282000603	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
990282000604	N-terminal plug; other site
990282000605	ligand-binding site [chemical binding]; other site
990282000606	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
990282000607	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
990282000608	Walker A/P-loop; other site
990282000609	ATP binding site [chemical binding]; other site
990282000610	Q-loop/lid; other site
990282000611	ABC transporter signature motif; other site
990282000612	Walker B; other site
990282000613	D-loop; other site
990282000614	H-loop/switch region; other site
990282000615	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
990282000616	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
990282000617	siderophore binding site; other site
990282000618	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
990282000619	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
990282000620	ABC-ATPase subunit  interface; other site
990282000621	dimer interface [polypeptide binding]; other site
990282000622	putative PBP binding regions; other site
990282000623	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
990282000624	ABC-ATPase subunit  interface; other site
990282000625	dimer interface [polypeptide binding]; other site
990282000626	putative PBP binding regions; other site
990282000627	putative fimbrial subunit StfA; Provisional; Region: PRK15283
990282000628	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
990282000629	PapC N-terminal domain; Region: PapC_N; pfam13954
990282000630	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
990282000631	PapC C-terminal domain; Region: PapC_C; pfam13953
990282000632	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
990282000633	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
990282000634	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
990282000635	putative minor fimbrial subunit StfE; Provisional; Region: PRK15286
990282000636	putative minor fimbrial subunit StfF; Provisional; Region: PRK15287
990282000637	putative minor fimbrial subunit StfG; Provisional; Region: PRK15288
990282000638	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
990282000639	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
990282000640	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
990282000641	inhibitor-cofactor binding pocket; inhibition site
990282000642	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282000643	catalytic residue [active]
990282000644	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
990282000645	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
990282000646	Cl- selectivity filter; other site
990282000647	Cl- binding residues [ion binding]; other site
990282000648	pore gating glutamate residue; other site
990282000649	dimer interface [polypeptide binding]; other site
990282000650	H+/Cl- coupling transport residue; other site
990282000651	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
990282000652	hypothetical protein; Provisional; Region: PRK10578
990282000653	UPF0126 domain; Region: UPF0126; pfam03458
990282000654	UPF0126 domain; Region: UPF0126; pfam03458
990282000655	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
990282000656	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
990282000657	cobalamin binding residues [chemical binding]; other site
990282000658	putative BtuC binding residues; other site
990282000659	dimer interface [polypeptide binding]; other site
990282000660	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
990282000661	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
990282000662	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
990282000663	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
990282000664	Zn2+ binding site [ion binding]; other site
990282000665	Mg2+ binding site [ion binding]; other site
990282000666	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
990282000667	serine endoprotease; Provisional; Region: PRK10942
990282000668	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
990282000669	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
990282000670	protein binding site [polypeptide binding]; other site
990282000671	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
990282000672	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
990282000673	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
990282000674	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
990282000675	hypothetical protein; Provisional; Region: PRK13677
990282000676	shikimate transporter; Provisional; Region: PRK09952
990282000677	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282000678	putative substrate translocation pore; other site
990282000679	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
990282000680	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
990282000681	trimer interface [polypeptide binding]; other site
990282000682	active site
990282000683	substrate binding site [chemical binding]; other site
990282000684	CoA binding site [chemical binding]; other site
990282000685	PII uridylyl-transferase; Provisional; Region: PRK05007
990282000686	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
990282000687	metal binding triad; other site
990282000688	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
990282000689	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
990282000690	Zn2+ binding site [ion binding]; other site
990282000691	Mg2+ binding site [ion binding]; other site
990282000692	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
990282000693	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
990282000694	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
990282000695	active site
990282000696	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
990282000697	rRNA interaction site [nucleotide binding]; other site
990282000698	S8 interaction site; other site
990282000699	putative laminin-1 binding site; other site
990282000700	elongation factor Ts; Provisional; Region: tsf; PRK09377
990282000701	UBA/TS-N domain; Region: UBA; pfam00627
990282000702	Elongation factor TS; Region: EF_TS; pfam00889
990282000703	Elongation factor TS; Region: EF_TS; pfam00889
990282000704	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
990282000705	putative nucleotide binding site [chemical binding]; other site
990282000706	uridine monophosphate binding site [chemical binding]; other site
990282000707	homohexameric interface [polypeptide binding]; other site
990282000708	ribosome recycling factor; Reviewed; Region: frr; PRK00083
990282000709	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
990282000710	hinge region; other site
990282000711	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
990282000712	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
990282000713	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
990282000714	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
990282000715	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
990282000716	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
990282000717	catalytic residue [active]
990282000718	putative FPP diphosphate  binding site; other site
990282000719	putative FPP binding hydrophobic cleft; other site
990282000720	dimer interface [polypeptide binding]; other site
990282000721	putative IPP diphosphate binding site; other site
990282000722	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
990282000723	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
990282000724	zinc metallopeptidase RseP; Provisional; Region: PRK10779
990282000725	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
990282000726	active site
990282000727	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
990282000728	protein binding site [polypeptide binding]; other site
990282000729	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
990282000730	protein binding site [polypeptide binding]; other site
990282000731	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
990282000732	putative substrate binding region [chemical binding]; other site
990282000733	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
990282000734	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
990282000735	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
990282000736	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
990282000737	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
990282000738	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
990282000739	Surface antigen; Region: Bac_surface_Ag; pfam01103
990282000740	periplasmic chaperone; Provisional; Region: PRK10780
990282000741	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
990282000742	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
990282000743	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
990282000744	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
990282000745	trimer interface [polypeptide binding]; other site
990282000746	active site
990282000747	UDP-GlcNAc binding site [chemical binding]; other site
990282000748	lipid binding site [chemical binding]; lipid-binding site
990282000749	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
990282000750	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
990282000751	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
990282000752	active site
990282000753	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
990282000754	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
990282000755	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
990282000756	RNA/DNA hybrid binding site [nucleotide binding]; other site
990282000757	active site
990282000758	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
990282000759	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
990282000760	putative active site [active]
990282000761	putative PHP Thumb interface [polypeptide binding]; other site
990282000762	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
990282000763	generic binding surface II; other site
990282000764	generic binding surface I; other site
990282000765	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
990282000766	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
990282000767	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
990282000768	Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some...; Region: chitinase_glyco_hydro_19; cd00325
990282000769	putative sugar binding site [chemical binding]; other site
990282000770	catalytic residues [active]
990282000771	PKD domain; Region: PKD; pfam00801
990282000772	lysine decarboxylase LdcC; Provisional; Region: PRK15399
990282000773	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
990282000774	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
990282000775	homodimer interface [polypeptide binding]; other site
990282000776	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282000777	catalytic residue [active]
990282000778	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
990282000779	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
990282000780	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
990282000781	putative metal binding site [ion binding]; other site
990282000782	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
990282000783	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
990282000784	Ligand Binding Site [chemical binding]; other site
990282000785	TilS substrate binding domain; Region: TilS; pfam09179
990282000786	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
990282000787	Rho-binding antiterminator; Provisional; Region: PRK11625
990282000788	hypothetical protein; Provisional; Region: PRK04964
990282000789	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
990282000790	hypothetical protein; Provisional; Region: PRK09256
990282000791	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
990282000792	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
990282000793	NlpE N-terminal domain; Region: NlpE; pfam04170
990282000794	prolyl-tRNA synthetase; Provisional; Region: PRK09194
990282000795	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
990282000796	dimer interface [polypeptide binding]; other site
990282000797	motif 1; other site
990282000798	active site
990282000799	motif 2; other site
990282000800	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
990282000801	putative deacylase active site [active]
990282000802	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
990282000803	active site
990282000804	motif 3; other site
990282000805	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
990282000806	anticodon binding site; other site
990282000807	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
990282000808	homodimer interaction site [polypeptide binding]; other site
990282000809	cofactor binding site; other site
990282000810	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
990282000811	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
990282000812	lipoprotein, YaeC family; Region: TIGR00363
990282000813	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282000814	dimer interface [polypeptide binding]; other site
990282000815	conserved gate region; other site
990282000816	ABC-ATPase subunit interface; other site
990282000817	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
990282000818	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
990282000819	Walker A/P-loop; other site
990282000820	ATP binding site [chemical binding]; other site
990282000821	Q-loop/lid; other site
990282000822	ABC transporter signature motif; other site
990282000823	Walker B; other site
990282000824	D-loop; other site
990282000825	H-loop/switch region; other site
990282000826	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
990282000827	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
990282000828	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282000829	active site
990282000830	motif I; other site
990282000831	motif II; other site
990282000832	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
990282000833	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
990282000834	active site
990282000835	catalytic tetrad [active]
990282000836	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282000837	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282000838	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
990282000839	putative effector binding pocket; other site
990282000840	dimerization interface [polypeptide binding]; other site
990282000841	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
990282000842	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282000843	putative substrate translocation pore; other site
990282000844	hypothetical protein; Provisional; Region: PRK05421
990282000845	putative catalytic site [active]
990282000846	putative metal binding site [ion binding]; other site
990282000847	putative phosphate binding site [ion binding]; other site
990282000848	putative catalytic site [active]
990282000849	putative phosphate binding site [ion binding]; other site
990282000850	putative metal binding site [ion binding]; other site
990282000851	Methyltransferase domain; Region: Methyltransf_23; pfam13489
990282000852	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282000853	S-adenosylmethionine binding site [chemical binding]; other site
990282000854	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
990282000855	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
990282000856	N-acetyl-D-glucosamine binding site [chemical binding]; other site
990282000857	catalytic residue [active]
990282000858	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
990282000859	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
990282000860	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
990282000861	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282000862	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
990282000863	RNA/DNA hybrid binding site [nucleotide binding]; other site
990282000864	active site
990282000865	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
990282000866	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
990282000867	active site
990282000868	catalytic site [active]
990282000869	substrate binding site [chemical binding]; other site
990282000870	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
990282000871	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
990282000872	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
990282000873	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
990282000874	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
990282000875	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3518
990282000876	Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only]; Region: ImpE; COG4455
990282000877	ImpE protein; Region: ImpE; pfam07024
990282000878	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
990282000879	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282000880	Walker A motif; other site
990282000881	ATP binding site [chemical binding]; other site
990282000882	Walker B motif; other site
990282000883	arginine finger; other site
990282000884	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282000885	Walker A motif; other site
990282000886	ATP binding site [chemical binding]; other site
990282000887	Walker B motif; other site
990282000888	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
990282000889	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
990282000890	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
990282000891	Protein of unknown function (DUF877); Region: DUF877; pfam05943
990282000892	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
990282000893	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
990282000894	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
990282000895	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
990282000896	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
990282000897	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
990282000898	hypothetical protein; Provisional; Region: PRK08126
990282000899	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
990282000900	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
990282000901	ligand binding site [chemical binding]; other site
990282000902	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
990282000903	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
990282000904	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
990282000905	Uncharacterized protein conserved in bacteria (DUF2094); Region: DUF2094; cl01611
990282000906	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4893
990282000907	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501
990282000908	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
990282000909	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
990282000910	Uncharacterized conserved protein [Function unknown]; Region: COG5435
990282000911	PAAR motif; Region: PAAR_motif; pfam05488
990282000912	RHS Repeat; Region: RHS_repeat; pfam05593
990282000913	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
990282000914	RHS Repeat; Region: RHS_repeat; pfam05593
990282000915	RHS Repeat; Region: RHS_repeat; pfam05593
990282000916	RHS protein; Region: RHS; pfam03527
990282000917	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
990282000918	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
990282000919	RHS protein; Region: RHS; pfam03527
990282000920	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
990282000921	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
990282000922	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
990282000923	Transposase; Region: HTH_Tnp_1; cl17663
990282000924	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
990282000925	Integrase core domain; Region: rve_3; pfam13683
990282000926	Saf-pilin pilus formation protein; Region: Saf-Nte_pilin; cl09697
990282000927	pili assembly chaperone protein SafB; Provisional; Region: PRK15224
990282000928	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
990282000929	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
990282000930	pilin outer membrane usher protein SafC; Provisional; Region: PRK15223
990282000931	PapC N-terminal domain; Region: PapC_N; pfam13954
990282000932	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
990282000933	PapC C-terminal domain; Region: PapC_C; pfam13953
990282000934	putative pilin structural protein SafD; Provisional; Region: PRK15222
990282000935	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
990282000936	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
990282000937	putative active site [active]
990282000938	putative metal binding site [ion binding]; other site
990282000939	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282000940	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282000941	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
990282000942	dimerization interface [polypeptide binding]; other site
990282000943	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
990282000944	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
990282000945	dimer interface [polypeptide binding]; other site
990282000946	C-N hydrolase family amidase; Provisional; Region: PRK10438
990282000947	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
990282000948	putative active site [active]
990282000949	catalytic triad [active]
990282000950	dimer interface [polypeptide binding]; other site
990282000951	multimer interface [polypeptide binding]; other site
990282000952	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
990282000953	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
990282000954	active site
990282000955	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
990282000956	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
990282000957	dimer interface [polypeptide binding]; other site
990282000958	active site
990282000959	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
990282000960	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
990282000961	putative active site [active]
990282000962	putative dimer interface [polypeptide binding]; other site
990282000963	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
990282000964	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
990282000965	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
990282000966	active site
990282000967	DNA polymerase IV; Validated; Region: PRK02406
990282000968	DNA binding site [nucleotide binding]
990282000969	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
990282000970	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
990282000971	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
990282000972	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
990282000973	metal binding site [ion binding]; metal-binding site
990282000974	dimer interface [polypeptide binding]; other site
990282000975	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
990282000976	active site
990282000977	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
990282000978	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
990282000979	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
990282000980	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
990282000981	trimer interface [polypeptide binding]; other site
990282000982	eyelet of channel; other site
990282000983	gamma-glutamyl kinase; Provisional; Region: PRK05429
990282000984	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
990282000985	nucleotide binding site [chemical binding]; other site
990282000986	homotetrameric interface [polypeptide binding]; other site
990282000987	putative phosphate binding site [ion binding]; other site
990282000988	putative allosteric binding site; other site
990282000989	PUA domain; Region: PUA; pfam01472
990282000990	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
990282000991	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
990282000992	putative catalytic cysteine [active]
990282000993	HTH-like domain; Region: HTH_21; pfam13276
990282000994	Integrase core domain; Region: rve; pfam00665
990282000995	Integrase core domain; Region: rve_2; pfam13333
990282000996	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
990282000997	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
990282000998	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282000999	putative substrate translocation pore; other site
990282001000	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
990282001001	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
990282001002	substrate binding site [chemical binding]; other site
990282001003	ligand binding site [chemical binding]; other site
990282001004	3-isopropylmalate dehydratase small subunit [Amino acid transport and metabolism]; Region: LeuD; COG0066
990282001005	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
990282001006	hypothetical protein; Provisional; Region: PRK14812
990282001007	substrate binding site [chemical binding]; other site
990282001008	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
990282001009	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
990282001010	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
990282001011	transcriptional activator TtdR; Provisional; Region: PRK09801
990282001012	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282001013	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
990282001014	putative effector binding pocket; other site
990282001015	putative dimerization interface [polypeptide binding]; other site
990282001016	YjzC-like protein; Region: YjzC; pfam14168
990282001017	fimbrial assembly chaperone StbE; Provisional; Region: PRK15246
990282001018	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
990282001019	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
990282001020	putative fimbrial usher protein StbD; Provisional; Region: PRK15247
990282001021	fimbrial outer membrane usher protein StbC; Provisional; Region: PRK15248
990282001022	PapC N-terminal domain; Region: PapC_N; pfam13954
990282001023	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
990282001024	PapC C-terminal domain; Region: PapC_C; pfam13953
990282001025	fimbrial chaperone protein StbB; Provisional; Region: PRK15249
990282001026	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
990282001027	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
990282001028	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
990282001029	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
990282001030	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
990282001031	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
990282001032	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
990282001033	DNA binding site [nucleotide binding]
990282001034	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
990282001035	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
990282001036	DNA binding residues [nucleotide binding]
990282001037	dimerization interface [polypeptide binding]; other site
990282001038	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
990282001039	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
990282001040	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
990282001041	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
990282001042	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
990282001043	HlyD family secretion protein; Region: HlyD_3; pfam13437
990282001044	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
990282001045	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
990282001046	metal-binding site [ion binding]
990282001047	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
990282001048	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282001049	motif II; other site
990282001050	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
990282001051	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
990282001052	DNA binding residues [nucleotide binding]
990282001053	dimer interface [polypeptide binding]; other site
990282001054	copper binding site [ion binding]; other site
990282001055	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
990282001056	metal-binding site [ion binding]
990282001057	putative sialic acid transporter; Region: 2A0112; TIGR00891
990282001058	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282001059	putative substrate translocation pore; other site
990282001060	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
990282001061	DNA methylase; Region: N6_N4_Mtase; cl17433
990282001062	DNA methylase; Region: N6_N4_Mtase; pfam01555
990282001063	type III restriction-modification system StyLTI enzyme res; Provisional; Region: PRK15483
990282001064	Type III restriction enzyme, res subunit; Region: ResIII; pfam04851
990282001065	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
990282001066	VRR-NUC domain; Region: VRR_NUC; pfam08774
990282001067	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
990282001068	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
990282001069	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
990282001070	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
990282001071	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
990282001072	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
990282001073	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
990282001074	N-terminal plug; other site
990282001075	ligand-binding site [chemical binding]; other site
990282001076	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
990282001077	hypothetical protein; Provisional; Region: PRK09929
990282001078	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
990282001079	Propionate catabolism activator; Region: PrpR_N; pfam06506
990282001080	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282001081	Walker A motif; other site
990282001082	ATP binding site [chemical binding]; other site
990282001083	Walker B motif; other site
990282001084	arginine finger; other site
990282001085	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
990282001086	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
990282001087	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
990282001088	tetramer interface [polypeptide binding]; other site
990282001089	active site
990282001090	Mg2+/Mn2+ binding site [ion binding]; other site
990282001091	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
990282001092	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
990282001093	dimer interface [polypeptide binding]; other site
990282001094	active site
990282001095	citrylCoA binding site [chemical binding]; other site
990282001096	oxalacetate/citrate binding site [chemical binding]; other site
990282001097	coenzyme A binding site [chemical binding]; other site
990282001098	catalytic triad [active]
990282001099	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
990282001100	2-methylcitrate dehydratase; Region: prpD; TIGR02330
990282001101	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
990282001102	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
990282001103	acyl-activating enzyme (AAE) consensus motif; other site
990282001104	AMP binding site [chemical binding]; other site
990282001105	active site
990282001106	CoA binding site [chemical binding]; other site
990282001107	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
990282001108	dimer interface [polypeptide binding]; other site
990282001109	active site
990282001110	Schiff base residues; other site
990282001111	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
990282001112	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
990282001113	Autotransporter beta-domain; Region: Autotransporter; pfam03797
990282001114	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
990282001115	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
990282001116	ligand binding site [chemical binding]; other site
990282001117	flexible hinge region; other site
990282001118	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
990282001119	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
990282001120	microcin B17 transporter; Reviewed; Region: PRK11098
990282001121	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
990282001122	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
990282001123	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
990282001124	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
990282001125	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
990282001126	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
990282001127	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3921
990282001128	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
990282001129	drug efflux system protein MdtG; Provisional; Region: PRK09874
990282001130	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282001131	putative substrate translocation pore; other site
990282001132	anti-RssB factor; Provisional; Region: PRK10244
990282001133	hypothetical protein; Provisional; Region: PRK11505
990282001134	psiF repeat; Region: PsiF_repeat; pfam07769
990282001135	psiF repeat; Region: PsiF_repeat; pfam07769
990282001136	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
990282001137	MASE2 domain; Region: MASE2; pfam05230
990282001138	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
990282001139	metal binding site [ion binding]; metal-binding site
990282001140	active site
990282001141	I-site; other site
990282001142	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
990282001143	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
990282001144	hypothetical protein; Validated; Region: PRK00124
990282001145	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
990282001146	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
990282001147	ADP binding site [chemical binding]; other site
990282001148	magnesium binding site [ion binding]; other site
990282001149	putative shikimate binding site; other site
990282001150	hypothetical protein; Provisional; Region: PRK10380
990282001151	hypothetical protein; Provisional; Region: PRK10481
990282001152	hypothetical protein; Provisional; Region: PRK10579
990282001153	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
990282001154	fructokinase; Reviewed; Region: PRK09557
990282001155	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
990282001156	nucleotide binding site [chemical binding]; other site
990282001157	MFS transport protein AraJ; Provisional; Region: PRK10091
990282001158	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282001159	putative substrate translocation pore; other site
990282001160	exonuclease subunit SbcC; Provisional; Region: PRK10246
990282001161	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282001162	Walker A/P-loop; other site
990282001163	ATP binding site [chemical binding]; other site
990282001164	Q-loop/lid; other site
990282001165	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282001166	ABC transporter signature motif; other site
990282001167	Walker B; other site
990282001168	D-loop; other site
990282001169	H-loop/switch region; other site
990282001170	exonuclease subunit SbcD; Provisional; Region: PRK10966
990282001171	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
990282001172	active site
990282001173	metal binding site [ion binding]; metal-binding site
990282001174	DNA binding site [nucleotide binding]
990282001175	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
990282001176	transcriptional regulator PhoB; Provisional; Region: PRK10161
990282001177	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282001178	active site
990282001179	phosphorylation site [posttranslational modification]
990282001180	intermolecular recognition site; other site
990282001181	dimerization interface [polypeptide binding]; other site
990282001182	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
990282001183	DNA binding site [nucleotide binding]
990282001184	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
990282001185	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
990282001186	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
990282001187	putative active site [active]
990282001188	heme pocket [chemical binding]; other site
990282001189	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282001190	dimer interface [polypeptide binding]; other site
990282001191	phosphorylation site [posttranslational modification]
990282001192	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282001193	ATP binding site [chemical binding]; other site
990282001194	Mg2+ binding site [ion binding]; other site
990282001195	G-X-G motif; other site
990282001196	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
990282001197	putative proline-specific permease; Provisional; Region: proY; PRK10580
990282001198	maltodextrin glucosidase; Provisional; Region: PRK10785
990282001199	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
990282001200	homodimer interface [polypeptide binding]; other site
990282001201	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
990282001202	active site
990282001203	homodimer interface [polypeptide binding]; other site
990282001204	catalytic site [active]
990282001205	peroxidase; Provisional; Region: PRK15000
990282001206	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
990282001207	dimer interface [polypeptide binding]; other site
990282001208	decamer (pentamer of dimers) interface [polypeptide binding]; other site
990282001209	catalytic triad [active]
990282001210	peroxidatic and resolving cysteines [active]
990282001211	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
990282001212	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
990282001213	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
990282001214	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
990282001215	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
990282001216	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
990282001217	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
990282001218	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
990282001219	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
990282001220	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
990282001221	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
990282001222	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
990282001223	Protein export membrane protein; Region: SecD_SecF; pfam02355
990282001224	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
990282001225	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
990282001226	Predicted transcriptional regulator [Transcription]; Region: COG2378
990282001227	HTH domain; Region: HTH_11; pfam08279
990282001228	WYL domain; Region: WYL; pfam13280
990282001229	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
990282001230	active site
990282001231	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
990282001232	hypothetical protein; Provisional; Region: PRK11530
990282001233	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
990282001234	ATP cone domain; Region: ATP-cone; pfam03477
990282001235	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
990282001236	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
990282001237	catalytic motif [active]
990282001238	Zn binding site [ion binding]; other site
990282001239	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
990282001240	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
990282001241	homopentamer interface [polypeptide binding]; other site
990282001242	active site
990282001243	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
990282001244	putative RNA binding site [nucleotide binding]; other site
990282001245	thiamine monophosphate kinase; Provisional; Region: PRK05731
990282001246	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
990282001247	ATP binding site [chemical binding]; other site
990282001248	dimerization interface [polypeptide binding]; other site
990282001249	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
990282001250	tetramer interfaces [polypeptide binding]; other site
990282001251	binuclear metal-binding site [ion binding]; other site
990282001252	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
990282001253	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
990282001254	active site
990282001255	catalytic tetrad [active]
990282001256	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
990282001257	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
990282001258	TPP-binding site; other site
990282001259	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
990282001260	PYR/PP interface [polypeptide binding]; other site
990282001261	dimer interface [polypeptide binding]; other site
990282001262	TPP binding site [chemical binding]; other site
990282001263	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
990282001264	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
990282001265	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
990282001266	substrate binding pocket [chemical binding]; other site
990282001267	chain length determination region; other site
990282001268	substrate-Mg2+ binding site; other site
990282001269	catalytic residues [active]
990282001270	aspartate-rich region 1; other site
990282001271	active site lid residues [active]
990282001272	aspartate-rich region 2; other site
990282001273	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
990282001274	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
990282001275	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
990282001276	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
990282001277	Ligand Binding Site [chemical binding]; other site
990282001278	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
990282001279	active site residue [active]
990282001280	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
990282001281	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282001282	dimer interface [polypeptide binding]; other site
990282001283	conserved gate region; other site
990282001284	ABC-ATPase subunit interface; other site
990282001285	2-aminoethylphosphonate transport system permease PhnU; Provisional; Region: PRK15050
990282001286	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282001287	dimer interface [polypeptide binding]; other site
990282001288	conserved gate region; other site
990282001289	putative PBP binding loops; other site
990282001290	ABC-ATPase subunit interface; other site
990282001291	2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Region: PhnT; TIGR03258
990282001292	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282001293	Walker A/P-loop; other site
990282001294	ATP binding site [chemical binding]; other site
990282001295	Q-loop/lid; other site
990282001296	ABC transporter signature motif; other site
990282001297	Walker B; other site
990282001298	D-loop; other site
990282001299	H-loop/switch region; other site
990282001300	TOBE domain; Region: TOBE_2; pfam08402
990282001301	2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional; Region: PRK15046
990282001302	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
990282001303	transcriptional regulator protein; Region: phnR; TIGR03337
990282001304	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282001305	DNA-binding site [nucleotide binding]; DNA binding site
990282001306	UTRA domain; Region: UTRA; pfam07702
990282001307	2-aminoethylphosphonate--pyruvate transaminase; Region: transamin_PhnW; TIGR02326
990282001308	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
990282001309	catalytic residue [active]
990282001310	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
990282001311	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282001312	motif II; other site
990282001313	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
990282001314	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
990282001315	conserved cys residue [active]
990282001316	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
990282001317	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
990282001318	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
990282001319	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
990282001320	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
990282001321	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282001322	Major Facilitator Superfamily; Region: MFS_1; pfam07690
990282001323	putative substrate translocation pore; other site
990282001324	Transposase DDE domain; Region: DDE_Tnp_1_5; pfam13737
990282001325	Sel1-like repeats; Region: SEL1; smart00671
990282001326	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
990282001327	Sel1 repeat; Region: Sel1; pfam08238
990282001328	Sel1-like repeats; Region: SEL1; smart00671
990282001329	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
990282001330	Sel1-like repeats; Region: SEL1; smart00671
990282001331	Sel1-like repeats; Region: SEL1; smart00671
990282001332	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
990282001333	UbiA prenyltransferase family; Region: UbiA; pfam01040
990282001334	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
990282001335	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
990282001336	Subunit I/III interface [polypeptide binding]; other site
990282001337	Subunit III/IV interface [polypeptide binding]; other site
990282001338	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
990282001339	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
990282001340	D-pathway; other site
990282001341	Putative ubiquinol binding site [chemical binding]; other site
990282001342	Low-spin heme (heme b) binding site [chemical binding]; other site
990282001343	Putative water exit pathway; other site
990282001344	Binuclear center (heme o3/CuB) [ion binding]; other site
990282001345	K-pathway; other site
990282001346	Putative proton exit pathway; other site
990282001347	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
990282001348	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
990282001349	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
990282001350	muropeptide transporter; Reviewed; Region: ampG; PRK11902
990282001351	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282001352	putative substrate translocation pore; other site
990282001353	hypothetical protein; Provisional; Region: PRK11627
990282001354	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
990282001355	transcriptional regulator BolA; Provisional; Region: PRK11628
990282001356	trigger factor; Provisional; Region: tig; PRK01490
990282001357	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
990282001358	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
990282001359	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
990282001360	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
990282001361	oligomer interface [polypeptide binding]; other site
990282001362	active site residues [active]
990282001363	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
990282001364	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
990282001365	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282001366	Walker A motif; other site
990282001367	ATP binding site [chemical binding]; other site
990282001368	Walker B motif; other site
990282001369	Iron permease FTR1 family; Region: FTR1; cl00475
990282001370	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
990282001371	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
990282001372	Found in ATP-dependent protease La (LON); Region: LON; smart00464
990282001373	Found in ATP-dependent protease La (LON); Region: LON; smart00464
990282001374	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282001375	Walker A motif; other site
990282001376	ATP binding site [chemical binding]; other site
990282001377	Walker B motif; other site
990282001378	arginine finger; other site
990282001379	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
990282001380	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
990282001381	IHF dimer interface [polypeptide binding]; other site
990282001382	IHF - DNA interface [nucleotide binding]; other site
990282001383	periplasmic folding chaperone; Provisional; Region: PRK10788
990282001384	SurA N-terminal domain; Region: SurA_N_3; cl07813
990282001385	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
990282001386	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
990282001387	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
990282001388	active site
990282001389	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
990282001390	Ligand Binding Site [chemical binding]; other site
990282001391	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
990282001392	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
990282001393	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
990282001394	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
990282001395	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282001396	active site
990282001397	motif I; other site
990282001398	motif II; other site
990282001399	Transposase IS200 like; Region: Y1_Tnp; pfam01797
990282001400	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
990282001401	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
990282001402	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
990282001403	catalytic residue [active]
990282001404	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
990282001405	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
990282001406	putative DNA binding site [nucleotide binding]; other site
990282001407	putative Zn2+ binding site [ion binding]; other site
990282001408	AsnC family; Region: AsnC_trans_reg; pfam01037
990282001409	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
990282001410	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
990282001411	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282001412	Walker A/P-loop; other site
990282001413	ATP binding site [chemical binding]; other site
990282001414	Q-loop/lid; other site
990282001415	ABC transporter signature motif; other site
990282001416	Walker B; other site
990282001417	D-loop; other site
990282001418	H-loop/switch region; other site
990282001419	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
990282001420	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
990282001421	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282001422	Walker A/P-loop; other site
990282001423	ATP binding site [chemical binding]; other site
990282001424	Q-loop/lid; other site
990282001425	ABC transporter signature motif; other site
990282001426	Walker B; other site
990282001427	D-loop; other site
990282001428	H-loop/switch region; other site
990282001429	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
990282001430	Nitrogen regulatory protein P-II; Region: P-II; smart00938
990282001431	ammonium transporter; Provisional; Region: PRK10666
990282001432	acyl-CoA thioesterase II; Provisional; Region: PRK10526
990282001433	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
990282001434	active site
990282001435	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
990282001436	catalytic triad [active]
990282001437	dimer interface [polypeptide binding]; other site
990282001438	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
990282001439	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
990282001440	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
990282001441	DNA binding site [nucleotide binding]
990282001442	active site
990282001443	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
990282001444	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
990282001445	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
990282001446	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
990282001447	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
990282001448	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
990282001449	maltose O-acetyltransferase; Provisional; Region: PRK10092
990282001450	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
990282001451	active site
990282001452	substrate binding site [chemical binding]; other site
990282001453	trimer interface [polypeptide binding]; other site
990282001454	CoA binding site [chemical binding]; other site
990282001455	gene expression modulator; Provisional; Region: PRK10945
990282001456	Hha toxicity attenuator; Provisional; Region: PRK10667
990282001457	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
990282001458	Protein export membrane protein; Region: SecD_SecF; cl14618
990282001459	Protein export membrane protein; Region: SecD_SecF; cl14618
990282001460	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
990282001461	HlyD family secretion protein; Region: HlyD_3; pfam13437
990282001462	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
990282001463	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
990282001464	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
990282001465	hypothetical protein; Provisional; Region: PRK11281
990282001466	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
990282001467	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; cl00779
990282001468	Mechanosensitive ion channel; Region: MS_channel; pfam00924
990282001469	Uncharacterized conserved protein [Function unknown]; Region: COG5464
990282001470	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
990282001471	hypothetical protein; Provisional; Region: PRK11038
990282001472	primosomal replication protein N''; Provisional; Region: PRK10093
990282001473	hypothetical protein; Provisional; Region: PRK10527
990282001474	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
990282001475	active site
990282001476	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
990282001477	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282001478	Walker A motif; other site
990282001479	ATP binding site [chemical binding]; other site
990282001480	Walker B motif; other site
990282001481	DNA polymerase III subunit delta'; Validated; Region: PRK08485
990282001482	arginine finger; other site
990282001483	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
990282001484	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
990282001485	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
990282001486	hypothetical protein; Validated; Region: PRK00153
990282001487	recombination protein RecR; Reviewed; Region: recR; PRK00076
990282001488	RecR protein; Region: RecR; pfam02132
990282001489	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
990282001490	putative active site [active]
990282001491	putative metal-binding site [ion binding]; other site
990282001492	tetramer interface [polypeptide binding]; other site
990282001493	heat shock protein 90; Provisional; Region: PRK05218
990282001494	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282001495	ATP binding site [chemical binding]; other site
990282001496	Mg2+ binding site [ion binding]; other site
990282001497	G-X-G motif; other site
990282001498	adenylate kinase; Reviewed; Region: adk; PRK00279
990282001499	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
990282001500	AMP-binding site [chemical binding]; other site
990282001501	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
990282001502	ferrochelatase; Reviewed; Region: hemH; PRK00035
990282001503	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
990282001504	C-terminal domain interface [polypeptide binding]; other site
990282001505	active site
990282001506	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
990282001507	active site
990282001508	N-terminal domain interface [polypeptide binding]; other site
990282001509	acetyl esterase; Provisional; Region: PRK10162
990282001510	inosine/guanosine kinase; Provisional; Region: PRK15074
990282001511	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
990282001512	putative cation:proton antiport protein; Provisional; Region: PRK10669
990282001513	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
990282001514	TrkA-N domain; Region: TrkA_N; pfam02254
990282001515	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282001516	Major Facilitator Superfamily; Region: MFS_1; pfam07690
990282001517	putative substrate translocation pore; other site
990282001518	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
990282001519	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
990282001520	active site
990282001521	metal binding site [ion binding]; metal-binding site
990282001522	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
990282001523	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
990282001524	putative deacylase active site [active]
990282001525	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
990282001526	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
990282001527	copper exporting ATPase; Provisional; Region: copA; PRK10671
990282001528	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
990282001529	metal-binding site [ion binding]
990282001530	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
990282001531	metal-binding site [ion binding]
990282001532	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
990282001533	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282001534	motif II; other site
990282001535	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
990282001536	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
990282001537	DNA binding residues [nucleotide binding]
990282001538	dimer interface [polypeptide binding]; other site
990282001539	copper binding site [ion binding]; other site
990282001540	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
990282001541	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
990282001542	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
990282001543	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
990282001544	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
990282001545	Walker A/P-loop; other site
990282001546	ATP binding site [chemical binding]; other site
990282001547	Q-loop/lid; other site
990282001548	ABC transporter signature motif; other site
990282001549	Walker B; other site
990282001550	D-loop; other site
990282001551	H-loop/switch region; other site
990282001552	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
990282001553	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
990282001554	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
990282001555	oxidoreductase; Provisional; Region: PRK08017
990282001556	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
990282001557	NADP binding site [chemical binding]; other site
990282001558	active site
990282001559	steroid binding site; other site
990282001560	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
990282001561	active site
990282001562	catalytic triad [active]
990282001563	oxyanion hole [active]
990282001564	switch loop; other site
990282001565	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
990282001566	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
990282001567	Walker A/P-loop; other site
990282001568	ATP binding site [chemical binding]; other site
990282001569	Q-loop/lid; other site
990282001570	ABC transporter signature motif; other site
990282001571	Walker B; other site
990282001572	D-loop; other site
990282001573	H-loop/switch region; other site
990282001574	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
990282001575	FtsX-like permease family; Region: FtsX; pfam02687
990282001576	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
990282001577	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
990282001578	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
990282001579	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
990282001580	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
990282001581	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
990282001582	Walker A/P-loop; other site
990282001583	ATP binding site [chemical binding]; other site
990282001584	Q-loop/lid; other site
990282001585	ABC transporter signature motif; other site
990282001586	Walker B; other site
990282001587	D-loop; other site
990282001588	H-loop/switch region; other site
990282001589	NIL domain; Region: NIL; pfam09383
990282001590	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282001591	dimer interface [polypeptide binding]; other site
990282001592	conserved gate region; other site
990282001593	ABC-ATPase subunit interface; other site
990282001594	Predicted ATPase [General function prediction only]; Region: COG2603
990282001595	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
990282001596	active site residue [active]
990282001597	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
990282001598	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282001599	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
990282001600	dimerization interface [polypeptide binding]; other site
990282001601	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
990282001602	ureidoglycolate hydrolase; Provisional; Region: PRK03606
990282001603	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
990282001604	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
990282001605	Bacterial transcriptional regulator; Region: IclR; pfam01614
990282001606	glyoxylate carboligase; Provisional; Region: PRK11269
990282001607	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
990282001608	PYR/PP interface [polypeptide binding]; other site
990282001609	dimer interface [polypeptide binding]; other site
990282001610	TPP binding site [chemical binding]; other site
990282001611	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
990282001612	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
990282001613	TPP-binding site [chemical binding]; other site
990282001614	hydroxypyruvate isomerase; Provisional; Region: PRK09997
990282001615	tartronate semialdehyde reductase; Provisional; Region: PRK15059
990282001616	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
990282001617	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282001618	Major Facilitator Superfamily; Region: MFS_1; pfam07690
990282001619	putative substrate translocation pore; other site
990282001620	nucleobase-cation-symport-1 (NCS1) transporters; solute-binding domain; Region: SLC-NCS1sbd; cd10323
990282001621	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
990282001622	substrate binding site [chemical binding]; other site
990282001623	Na binding site [ion binding]; other site
990282001624	allantoinase; Provisional; Region: PRK08044
990282001625	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
990282001626	active site
990282001627	putative uracil/xanthine transporter; Provisional; Region: PRK11412
990282001628	glycerate kinase II; Provisional; Region: PRK09932
990282001629	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
990282001630	Mif2/CENP-C like; Region: Mif2; pfam11699
990282001631	Cupin domain; Region: Cupin_2; pfam07883
990282001632	allantoate amidohydrolase; Region: AllC; TIGR03176
990282001633	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
990282001634	active site
990282001635	metal binding site [ion binding]; metal-binding site
990282001636	dimer interface [polypeptide binding]; other site
990282001637	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
990282001638	membrane protein FdrA; Validated; Region: PRK06091
990282001639	CoA binding domain; Region: CoA_binding; pfam02629
990282001640	CoA-ligase; Region: Ligase_CoA; pfam00549
990282001641	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
990282001642	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
990282001643	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
990282001644	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
990282001645	putative substrate binding site [chemical binding]; other site
990282001646	nucleotide binding site [chemical binding]; other site
990282001647	nucleotide binding site [chemical binding]; other site
990282001648	homodimer interface [polypeptide binding]; other site
990282001649	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
990282001650	ATP-grasp domain; Region: ATP-grasp; pfam02222
990282001651	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
990282001652	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
990282001653	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
990282001654	putative active site [active]
990282001655	putative metal binding site [ion binding]; other site
990282001656	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
990282001657	substrate binding site [chemical binding]; other site
990282001658	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
990282001659	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
990282001660	active site
990282001661	HIGH motif; other site
990282001662	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
990282001663	KMSKS motif; other site
990282001664	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
990282001665	tRNA binding surface [nucleotide binding]; other site
990282001666	anticodon binding site; other site
990282001667	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4727
990282001668	Uncharacterized protein conserved in bacteria (DUF2145); Region: DUF2145; pfam09916
990282001669	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
990282001670	ribosome-associated protein; Provisional; Region: PRK11507
990282001671	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
990282001672	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
990282001673	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
990282001674	homodimer interface [polypeptide binding]; other site
990282001675	NADP binding site [chemical binding]; other site
990282001676	substrate binding site [chemical binding]; other site
990282001677	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
990282001678	fimbrial protein FimI; Provisional; Region: PRK15200
990282001679	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
990282001680	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
990282001681	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
990282001682	outer membrane usher protein FimD; Provisional; Region: PRK15198
990282001683	PapC N-terminal domain; Region: PapC_N; pfam13954
990282001684	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
990282001685	PapC C-terminal domain; Region: PapC_C; pfam13953
990282001686	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
990282001687	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
990282001688	transcriptional regulator FimZ; Provisional; Region: PRK09935
990282001689	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282001690	active site
990282001691	phosphorylation site [posttranslational modification]
990282001692	intermolecular recognition site; other site
990282001693	dimerization interface [polypeptide binding]; other site
990282001694	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282001695	DNA binding residues [nucleotide binding]
990282001696	dimerization interface [polypeptide binding]; other site
990282001697	fimbriae regulatory protein FimW; Provisional; Region: PRK15201
990282001698	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282001699	DNA binding residues [nucleotide binding]
990282001700	dimerization interface [polypeptide binding]; other site
990282001701	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
990282001702	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
990282001703	Transposase; Region: HTH_Tnp_1; pfam01527
990282001704	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
990282001705	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
990282001706	Ligand binding site; other site
990282001707	Putative Catalytic site; other site
990282001708	DXD motif; other site
990282001709	Predicted membrane protein [Function unknown]; Region: COG2246
990282001710	GtrA-like protein; Region: GtrA; pfam04138
990282001711	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282001712	ATP binding site [chemical binding]; other site
990282001713	Mg2+ binding site [ion binding]; other site
990282001714	G-X-G motif; other site
990282001715	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
990282001716	Cupin; Region: Cupin_6; pfam12852
990282001717	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
990282001718	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282001719	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282001720	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
990282001721	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
990282001722	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
990282001723	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
990282001724	Predicted membrane protein [Function unknown]; Region: COG3059
990282001725	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
990282001726	phenylalanine transporter; Provisional; Region: PRK10249
990282001727	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
990282001728	Mechanosensitive ion channel; Region: MS_channel; pfam00924
990282001729	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
990282001730	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
990282001731	active site
990282001732	oxyanion hole [active]
990282001733	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
990282001734	catalytic triad [active]
990282001735	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
990282001736	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
990282001737	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282001738	ATP binding site [chemical binding]; other site
990282001739	Walker B motif; other site
990282001740	arginine finger; other site
990282001741	Transcriptional antiterminator [Transcription]; Region: COG3933
990282001742	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
990282001743	active pocket/dimerization site; other site
990282001744	active site
990282001745	phosphorylation site [posttranslational modification]
990282001746	PRD domain; Region: PRD; pfam00874
990282001747	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
990282001748	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
990282001749	putative active site [active]
990282001750	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
990282001751	dimer interface [polypeptide binding]; other site
990282001752	active site
990282001753	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
990282001754	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
990282001755	dimer interface [polypeptide binding]; other site
990282001756	active site
990282001757	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
990282001758	dimer interface [polypeptide binding]; other site
990282001759	active site
990282001760	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
990282001761	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
990282001762	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
990282001763	active site
990282001764	phosphorylation site [posttranslational modification]
990282001765	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
990282001766	active pocket/dimerization site; other site
990282001767	active site
990282001768	phosphorylation site [posttranslational modification]
990282001769	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
990282001770	dimer interface [polypeptide binding]; other site
990282001771	FMN binding site [chemical binding]; other site
990282001772	hypothetical protein; Provisional; Region: PRK10250
990282001773	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
990282001774	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
990282001775	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
990282001776	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282001777	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
990282001778	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
990282001779	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
990282001780	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
990282001781	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
990282001782	outer membrane receptor FepA; Provisional; Region: PRK13524
990282001783	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
990282001784	N-terminal plug; other site
990282001785	ligand-binding site [chemical binding]; other site
990282001786	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
990282001787	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
990282001788	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
990282001789	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
990282001790	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
990282001791	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
990282001792	acyl-activating enzyme (AAE) consensus motif; other site
990282001793	AMP binding site [chemical binding]; other site
990282001794	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
990282001795	LPS O-antigen length regulator; Provisional; Region: PRK10381
990282001796	Chain length determinant protein; Region: Wzz; pfam02706
990282001797	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
990282001798	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
990282001799	Walker A/P-loop; other site
990282001800	ATP binding site [chemical binding]; other site
990282001801	Q-loop/lid; other site
990282001802	ABC transporter signature motif; other site
990282001803	Walker B; other site
990282001804	D-loop; other site
990282001805	H-loop/switch region; other site
990282001806	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
990282001807	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
990282001808	ABC-ATPase subunit  interface; other site
990282001809	dimer interface [polypeptide binding]; other site
990282001810	putative PBP binding regions; other site
990282001811	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
990282001812	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
990282001813	ABC-ATPase subunit  interface; other site
990282001814	dimer interface [polypeptide binding]; other site
990282001815	putative PBP binding regions; other site
990282001816	enterobactin exporter EntS; Provisional; Region: PRK10489
990282001817	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282001818	putative substrate translocation pore; other site
990282001819	ABC-type Fe2+-enterobactin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG4592
990282001820	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
990282001821	siderophore binding site; other site
990282001822	isochorismate synthase EntC; Provisional; Region: PRK15016
990282001823	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
990282001824	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
990282001825	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
990282001826	acyl-activating enzyme (AAE) consensus motif; other site
990282001827	active site
990282001828	AMP binding site [chemical binding]; other site
990282001829	substrate binding site [chemical binding]; other site
990282001830	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
990282001831	hydrophobic substrate binding pocket; other site
990282001832	Isochorismatase family; Region: Isochorismatase; pfam00857
990282001833	active site
990282001834	conserved cis-peptide bond; other site
990282001835	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
990282001836	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
990282001837	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
990282001838	putative NAD(P) binding site [chemical binding]; other site
990282001839	active site
990282001840	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
990282001841	CoenzymeA binding site [chemical binding]; other site
990282001842	subunit interaction site [polypeptide binding]; other site
990282001843	PHB binding site; other site
990282001844	carbon starvation protein A; Provisional; Region: PRK15015
990282001845	Carbon starvation protein CstA; Region: CstA; pfam02554
990282001846	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
990282001847	Uncharacterized small protein [Function unknown]; Region: COG2879
990282001848	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
990282001849	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
990282001850	putative active site [active]
990282001851	metal binding site [ion binding]; metal-binding site
990282001852	methionine aminotransferase; Validated; Region: PRK09082
990282001853	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
990282001854	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282001855	homodimer interface [polypeptide binding]; other site
990282001856	catalytic residue [active]
990282001857	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
990282001858	ParB-like nuclease domain; Region: ParBc; pfam02195
990282001859	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
990282001860	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
990282001861	Active Sites [active]
990282001862	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
990282001863	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
990282001864	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282001865	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
990282001866	dimerization interface [polypeptide binding]; other site
990282001867	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
990282001868	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
990282001869	dimerization domain [polypeptide binding]; other site
990282001870	dimer interface [polypeptide binding]; other site
990282001871	catalytic residues [active]
990282001872	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
990282001873	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
990282001874	dimer interface [polypeptide binding]; other site
990282001875	decamer (pentamer of dimers) interface [polypeptide binding]; other site
990282001876	catalytic triad [active]
990282001877	peroxidatic and resolving cysteines [active]
990282001878	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
990282001879	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
990282001880	catalytic residue [active]
990282001881	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
990282001882	catalytic residues [active]
990282001883	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
990282001884	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
990282001885	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
990282001886	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
990282001887	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
990282001888	putative [4Fe-4S] binding site [ion binding]; other site
990282001889	putative molybdopterin cofactor binding site [chemical binding]; other site
990282001890	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
990282001891	molybdopterin cofactor binding site; other site
990282001892	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
990282001893	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
990282001894	Ligand Binding Site [chemical binding]; other site
990282001895	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
990282001896	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
990282001897	NAD binding site [chemical binding]; other site
990282001898	catalytic Zn binding site [ion binding]; other site
990282001899	structural Zn binding site [ion binding]; other site
990282001900	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
990282001901	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
990282001902	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
990282001903	B1 nucleotide binding pocket [chemical binding]; other site
990282001904	B2 nucleotide binding pocket [chemical binding]; other site
990282001905	CAS motifs; other site
990282001906	active site
990282001907	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
990282001908	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
990282001909	transmembrane helices; other site
990282001910	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
990282001911	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
990282001912	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
990282001913	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
990282001914	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
990282001915	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
990282001916	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
990282001917	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
990282001918	putative active site [active]
990282001919	(T/H)XGH motif; other site
990282001920	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
990282001921	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
990282001922	putative active site [active]
990282001923	heme pocket [chemical binding]; other site
990282001924	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282001925	ATP binding site [chemical binding]; other site
990282001926	Mg2+ binding site [ion binding]; other site
990282001927	G-X-G motif; other site
990282001928	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
990282001929	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282001930	active site
990282001931	phosphorylation site [posttranslational modification]
990282001932	intermolecular recognition site; other site
990282001933	dimerization interface [polypeptide binding]; other site
990282001934	Transcriptional regulator; Region: CitT; pfam12431
990282001935	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
990282001936	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
990282001937	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
990282001938	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
990282001939	DNA-binding site [nucleotide binding]; DNA binding site
990282001940	RNA-binding motif; other site
990282001941	chromosome condensation membrane protein; Provisional; Region: PRK14196
990282001942	Predicted amidohydrolase [General function prediction only]; Region: COG0388
990282001943	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
990282001944	putative active site [active]
990282001945	catalytic triad [active]
990282001946	putative dimer interface [polypeptide binding]; other site
990282001947	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
990282001948	lipoyl synthase; Provisional; Region: PRK05481
990282001949	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282001950	FeS/SAM binding site; other site
990282001951	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
990282001952	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282001953	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
990282001954	substrate binding pocket [chemical binding]; other site
990282001955	dimerization interface [polypeptide binding]; other site
990282001956	lipoate-protein ligase B; Provisional; Region: PRK14342
990282001957	hypothetical protein; Provisional; Region: PRK04998
990282001958	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
990282001959	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
990282001960	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
990282001961	rare lipoprotein A; Provisional; Region: PRK10672
990282001962	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
990282001963	Sporulation related domain; Region: SPOR; pfam05036
990282001964	cell wall shape-determining protein; Provisional; Region: PRK10794
990282001965	penicillin-binding protein 2; Provisional; Region: PRK10795
990282001966	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
990282001967	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
990282001968	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
990282001969	ribosome-associated protein; Provisional; Region: PRK11538
990282001970	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
990282001971	catalytic core [active]
990282001972	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
990282001973	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
990282001974	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282001975	homodimer interface [polypeptide binding]; other site
990282001976	catalytic residue [active]
990282001977	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
990282001978	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
990282001979	active site
990282001980	(T/H)XGH motif; other site
990282001981	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
990282001982	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
990282001983	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
990282001984	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
990282001985	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
990282001986	HIGH motif; other site
990282001987	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
990282001988	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
990282001989	active site
990282001990	KMSKS motif; other site
990282001991	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
990282001992	tRNA binding surface [nucleotide binding]; other site
990282001993	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
990282001994	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
990282001995	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
990282001996	Propionate catabolism activator; Region: PrpR_N; pfam06506
990282001997	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
990282001998	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282001999	Walker A motif; other site
990282002000	ATP binding site [chemical binding]; other site
990282002001	Walker B motif; other site
990282002002	arginine finger; other site
990282002003	hypothetical protein; Provisional; Region: PRK11032
990282002004	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
990282002005	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
990282002006	Sel1-like repeats; Region: SEL1; smart00671
990282002007	Sel1-like repeats; Region: SEL1; smart00671
990282002008	Sel1-like repeats; Region: SEL1; smart00671
990282002009	Sel1-like repeats; Region: SEL1; smart00671
990282002010	Sel1-like repeats; Region: SEL1; smart00671
990282002011	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
990282002012	DnaJ molecular chaperone homology domain; Region: DnaJ; smart00271
990282002013	HSP70 interaction site [polypeptide binding]; other site
990282002014	DnaJ domain; Region: DnaJ; pfam00226
990282002015	HSP70 interaction site [polypeptide binding]; other site
990282002016	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
990282002017	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
990282002018	nucleotide binding site [chemical binding]; other site
990282002019	putative NEF/HSP70 interaction site [polypeptide binding]; other site
990282002020	SBD interface [polypeptide binding]; other site
990282002021	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
990282002022	active site
990282002023	tetramer interface [polypeptide binding]; other site
990282002024	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
990282002025	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
990282002026	Walker A/P-loop; other site
990282002027	ATP binding site [chemical binding]; other site
990282002028	Q-loop/lid; other site
990282002029	ABC transporter signature motif; other site
990282002030	Walker B; other site
990282002031	D-loop; other site
990282002032	H-loop/switch region; other site
990282002033	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
990282002034	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282002035	dimer interface [polypeptide binding]; other site
990282002036	conserved gate region; other site
990282002037	putative PBP binding loops; other site
990282002038	ABC-ATPase subunit interface; other site
990282002039	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
990282002040	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282002041	dimer interface [polypeptide binding]; other site
990282002042	conserved gate region; other site
990282002043	putative PBP binding loops; other site
990282002044	ABC-ATPase subunit interface; other site
990282002045	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
990282002046	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
990282002047	substrate binding pocket [chemical binding]; other site
990282002048	membrane-bound complex binding site; other site
990282002049	hinge residues; other site
990282002050	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
990282002051	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
990282002052	putative active site [active]
990282002053	catalytic triad [active]
990282002054	putative dimer interface [polypeptide binding]; other site
990282002055	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
990282002056	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
990282002057	Transporter associated domain; Region: CorC_HlyC; smart01091
990282002058	metal-binding heat shock protein; Provisional; Region: PRK00016
990282002059	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
990282002060	PhoH-like protein; Region: PhoH; pfam02562
990282002061	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
990282002062	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
990282002063	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282002064	FeS/SAM binding site; other site
990282002065	TRAM domain; Region: TRAM; pfam01938
990282002066	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
990282002067	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
990282002068	asparagine synthetase B; Provisional; Region: asnB; PRK09431
990282002069	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
990282002070	active site
990282002071	dimer interface [polypeptide binding]; other site
990282002072	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
990282002073	Ligand Binding Site [chemical binding]; other site
990282002074	Molecular Tunnel; other site
990282002075	UMP phosphatase; Provisional; Region: PRK10444
990282002076	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282002077	active site
990282002078	motif I; other site
990282002079	motif II; other site
990282002080	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282002081	MarR family; Region: MarR; pfam01047
990282002082	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
990282002083	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
990282002084	nucleotide binding site [chemical binding]; other site
990282002085	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
990282002086	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
990282002087	active site
990282002088	dimer interface [polypeptide binding]; other site
990282002089	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
990282002090	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
990282002091	active site
990282002092	trimer interface [polypeptide binding]; other site
990282002093	allosteric site; other site
990282002094	active site lid [active]
990282002095	hexamer (dimer of trimers) interface [polypeptide binding]; other site
990282002096	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
990282002097	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
990282002098	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
990282002099	active site turn [active]
990282002100	phosphorylation site [posttranslational modification]
990282002101	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
990282002102	HPr interaction site; other site
990282002103	glycerol kinase (GK) interaction site [polypeptide binding]; other site
990282002104	active site
990282002105	phosphorylation site [posttranslational modification]
990282002106	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
990282002107	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
990282002108	active site
990282002109	HIGH motif; other site
990282002110	nucleotide binding site [chemical binding]; other site
990282002111	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
990282002112	KMSKS motif; other site
990282002113	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
990282002114	outer membrane porin, OprD family; Region: OprD; pfam03573
990282002115	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
990282002116	YbfN-like lipoprotein; Region: YbfN; pfam13982
990282002117	citrate-proton symporter; Provisional; Region: PRK15075
990282002118	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282002119	putative substrate translocation pore; other site
990282002120	tricarballylate utilization protein B; Provisional; Region: PRK15033
990282002121	tricarballylate dehydrogenase; Validated; Region: PRK08274
990282002122	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
990282002123	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282002124	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282002125	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
990282002126	putative dimerization interface [polypeptide binding]; other site
990282002127	ferric uptake regulator; Provisional; Region: fur; PRK09462
990282002128	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
990282002129	metal binding site 2 [ion binding]; metal-binding site
990282002130	putative DNA binding helix; other site
990282002131	metal binding site 1 [ion binding]; metal-binding site
990282002132	dimer interface [polypeptide binding]; other site
990282002133	structural Zn2+ binding site [ion binding]; other site
990282002134	flavodoxin FldA; Validated; Region: PRK09267
990282002135	acyl-CoA esterase; Provisional; Region: PRK10673
990282002136	PGAP1-like protein; Region: PGAP1; pfam07819
990282002137	replication initiation regulator SeqA; Provisional; Region: PRK11187
990282002138	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
990282002139	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
990282002140	active site
990282002141	substrate binding site [chemical binding]; other site
990282002142	metal binding site [ion binding]; metal-binding site
990282002143	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
990282002144	putrescine transporter; Provisional; Region: potE; PRK10655
990282002145	ornithine decarboxylase; Provisional; Region: PRK13578
990282002146	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
990282002147	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
990282002148	homodimer interface [polypeptide binding]; other site
990282002149	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282002150	catalytic residue [active]
990282002151	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
990282002152	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
990282002153	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282002154	active site
990282002155	phosphorylation site [posttranslational modification]
990282002156	intermolecular recognition site; other site
990282002157	dimerization interface [polypeptide binding]; other site
990282002158	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
990282002159	DNA binding site [nucleotide binding]
990282002160	sensor protein KdpD; Provisional; Region: PRK10490
990282002161	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
990282002162	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
990282002163	Ligand Binding Site [chemical binding]; other site
990282002164	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
990282002165	GAF domain; Region: GAF_3; pfam13492
990282002166	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282002167	dimer interface [polypeptide binding]; other site
990282002168	phosphorylation site [posttranslational modification]
990282002169	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282002170	ATP binding site [chemical binding]; other site
990282002171	Mg2+ binding site [ion binding]; other site
990282002172	G-X-G motif; other site
990282002173	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
990282002174	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
990282002175	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
990282002176	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
990282002177	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
990282002178	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
990282002179	DNA photolyase; Region: DNA_photolyase; pfam00875
990282002180	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
990282002181	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282002182	putative substrate translocation pore; other site
990282002183	POT family; Region: PTR2; pfam00854
990282002184	Uncharacterized conserved protein [Function unknown]; Region: COG0327
990282002185	metal-binding protein; Provisional; Region: PRK10799
990282002186	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
990282002187	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
990282002188	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
990282002189	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
990282002190	putative active site [active]
990282002191	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
990282002192	active site
990282002193	DNA binding site [nucleotide binding]
990282002194	Int/Topo IB signature motif; other site
990282002195	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
990282002196	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
990282002197	UDP-galactopyranose mutase; Region: GLF; pfam03275
990282002198	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
990282002199	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
990282002200	active site
990282002201	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
990282002202	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
990282002203	putative ADP-binding pocket [chemical binding]; other site
990282002204	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
990282002205	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
990282002206	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
990282002207	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
990282002208	Walker A/P-loop; other site
990282002209	ATP binding site [chemical binding]; other site
990282002210	Q-loop/lid; other site
990282002211	ABC transporter signature motif; other site
990282002212	Walker B; other site
990282002213	D-loop; other site
990282002214	H-loop/switch region; other site
990282002215	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
990282002216	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
990282002217	active site
990282002218	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
990282002219	active site
990282002220	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG5610
990282002221	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
990282002222	endonuclease VIII; Provisional; Region: PRK10445
990282002223	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
990282002224	DNA binding site [nucleotide binding]
990282002225	catalytic residue [active]
990282002226	putative catalytic residues [active]
990282002227	H2TH interface [polypeptide binding]; other site
990282002228	intercalation triad [nucleotide binding]; other site
990282002229	substrate specificity determining residue; other site
990282002230	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
990282002231	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
990282002232	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
990282002233	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
990282002234	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
990282002235	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
990282002236	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
990282002237	dimer interface [polypeptide binding]; other site
990282002238	active site
990282002239	citrylCoA binding site [chemical binding]; other site
990282002240	NADH binding [chemical binding]; other site
990282002241	cationic pore residues; other site
990282002242	oxalacetate/citrate binding site [chemical binding]; other site
990282002243	coenzyme A binding site [chemical binding]; other site
990282002244	catalytic triad [active]
990282002245	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
990282002246	Iron-sulfur protein interface; other site
990282002247	proximal quinone binding site [chemical binding]; other site
990282002248	SdhD (CybS) interface [polypeptide binding]; other site
990282002249	proximal heme binding site [chemical binding]; other site
990282002250	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
990282002251	SdhC subunit interface [polypeptide binding]; other site
990282002252	proximal heme binding site [chemical binding]; other site
990282002253	cardiolipin binding site; other site
990282002254	Iron-sulfur protein interface; other site
990282002255	proximal quinone binding site [chemical binding]; other site
990282002256	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
990282002257	L-aspartate oxidase; Provisional; Region: PRK06175
990282002258	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
990282002259	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
990282002260	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
990282002261	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
990282002262	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
990282002263	TPP-binding site [chemical binding]; other site
990282002264	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
990282002265	dimer interface [polypeptide binding]; other site
990282002266	PYR/PP interface [polypeptide binding]; other site
990282002267	TPP binding site [chemical binding]; other site
990282002268	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
990282002269	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
990282002270	E3 interaction surface; other site
990282002271	lipoyl attachment site [posttranslational modification]; other site
990282002272	e3 binding domain; Region: E3_binding; pfam02817
990282002273	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
990282002274	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
990282002275	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
990282002276	CoA-ligase; Region: Ligase_CoA; pfam00549
990282002277	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
990282002278	CoA binding domain; Region: CoA_binding; smart00881
990282002279	CoA-ligase; Region: Ligase_CoA; pfam00549
990282002280	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
990282002281	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
990282002282	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
990282002283	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
990282002284	Predicted outer membrane lipoprotein [Function unknown]; Region: COG4890
990282002285	hypothetical protein; Provisional; Region: PRK10588
990282002286	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
990282002287	active site
990282002288	colicin uptake protein TolQ; Provisional; Region: PRK10801
990282002289	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
990282002290	colicin uptake protein TolR; Provisional; Region: PRK11024
990282002291	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
990282002292	TolA C-terminal; Region: TolA; pfam06519
990282002293	translocation protein TolB; Provisional; Region: tolB; PRK03629
990282002294	TolB amino-terminal domain; Region: TolB_N; pfam04052
990282002295	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
990282002296	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
990282002297	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
990282002298	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
990282002299	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
990282002300	ligand binding site [chemical binding]; other site
990282002301	tol-pal system protein YbgF; Provisional; Region: PRK10803
990282002302	Tetratricopeptide repeat; Region: TPR_6; pfam13174
990282002303	Tetratricopeptide repeat; Region: TPR_6; pfam13174
990282002304	quinolinate synthetase; Provisional; Region: PRK09375
990282002305	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
990282002306	zinc transporter ZitB; Provisional; Region: PRK03557
990282002307	YbgS-like protein; Region: YbgS; pfam13985
990282002308	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
990282002309	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
990282002310	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain [Energy production and conversion]; Region: FumA; COG1838
990282002311	fumarate hydratase; Provisional; Region: PRK06246
990282002312	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282002313	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282002314	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
990282002315	dimerization interface [polypeptide binding]; other site
990282002316	cell density-dependent motility repressor; Provisional; Region: PRK10082
990282002317	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282002318	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
990282002319	dimerization interface [polypeptide binding]; other site
990282002320	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
990282002321	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
990282002322	transmembrane helices; other site
990282002323	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
990282002324	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
990282002325	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
990282002326	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
990282002327	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
990282002328	dimer interface [polypeptide binding]; other site
990282002329	putative PBP binding regions; other site
990282002330	ABC-ATPase subunit  interface; other site
990282002331	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
990282002332	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
990282002333	Walker A/P-loop; other site
990282002334	ATP binding site [chemical binding]; other site
990282002335	Q-loop/lid; other site
990282002336	ABC transporter signature motif; other site
990282002337	Walker B; other site
990282002338	D-loop; other site
990282002339	H-loop/switch region; other site
990282002340	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
990282002341	catalytic core [active]
990282002342	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
990282002343	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
990282002344	active site
990282002345	catalytic residues [active]
990282002346	galactokinase; Provisional; Region: PRK05101
990282002347	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
990282002348	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
990282002349	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
990282002350	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
990282002351	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
990282002352	dimer interface [polypeptide binding]; other site
990282002353	active site
990282002354	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
990282002355	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
990282002356	NAD binding site [chemical binding]; other site
990282002357	homodimer interface [polypeptide binding]; other site
990282002358	active site
990282002359	substrate binding site [chemical binding]; other site
990282002360	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4714
990282002361	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
990282002362	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282002363	Walker A/P-loop; other site
990282002364	ATP binding site [chemical binding]; other site
990282002365	Q-loop/lid; other site
990282002366	ABC transporter signature motif; other site
990282002367	Walker B; other site
990282002368	D-loop; other site
990282002369	H-loop/switch region; other site
990282002370	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282002371	Walker A/P-loop; other site
990282002372	ATP binding site [chemical binding]; other site
990282002373	Q-loop/lid; other site
990282002374	ABC transporter signature motif; other site
990282002375	Walker B; other site
990282002376	D-loop; other site
990282002377	H-loop/switch region; other site
990282002378	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
990282002379	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
990282002380	molybdenum-pterin binding domain; Region: Mop; TIGR00638
990282002381	TOBE domain; Region: TOBE; pfam03459
990282002382	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
990282002383	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
990282002384	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
990282002385	substrate binding pocket [chemical binding]; other site
990282002386	membrane-bound complex binding site; other site
990282002387	hinge residues; other site
990282002388	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
990282002389	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282002390	dimer interface [polypeptide binding]; other site
990282002391	conserved gate region; other site
990282002392	putative PBP binding loops; other site
990282002393	ABC-ATPase subunit interface; other site
990282002394	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
990282002395	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282002396	Walker A/P-loop; other site
990282002397	ATP binding site [chemical binding]; other site
990282002398	Q-loop/lid; other site
990282002399	ABC transporter signature motif; other site
990282002400	Walker B; other site
990282002401	D-loop; other site
990282002402	H-loop/switch region; other site
990282002403	molybdenum-pterin binding domain; Region: Mop; TIGR00638
990282002404	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
990282002405	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282002406	active site
990282002407	motif I; other site
990282002408	motif II; other site
990282002409	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282002410	6-phosphogluconolactonase; Provisional; Region: PRK11028
990282002411	acyl-CoA thioesterase; Provisional; Region: PRK10531
990282002412	putative pectinesterase; Region: PLN02432; cl01911
990282002413	imidazolonepropionase; Validated; Region: PRK09356
990282002414	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
990282002415	active site
990282002416	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
990282002417	putative active site [active]
990282002418	putative metal binding site [ion binding]; other site
990282002419	histidine utilization repressor; Provisional; Region: PRK14999
990282002420	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282002421	DNA-binding site [nucleotide binding]; DNA binding site
990282002422	UTRA domain; Region: UTRA; pfam07702
990282002423	urocanate hydratase; Provisional; Region: PRK05414
990282002424	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
990282002425	active sites [active]
990282002426	tetramer interface [polypeptide binding]; other site
990282002427	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
990282002428	substrate binding site [chemical binding]; other site
990282002429	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
990282002430	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
990282002431	inhibitor-cofactor binding pocket; inhibition site
990282002432	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282002433	catalytic residue [active]
990282002434	biotin synthase; Provisional; Region: PRK15108
990282002435	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282002436	FeS/SAM binding site; other site
990282002437	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
990282002438	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
990282002439	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
990282002440	substrate-cofactor binding pocket; other site
990282002441	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282002442	catalytic residue [active]
990282002443	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
990282002444	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282002445	S-adenosylmethionine binding site [chemical binding]; other site
990282002446	AAA domain; Region: AAA_26; pfam13500
990282002447	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
990282002448	excinuclease ABC subunit B; Provisional; Region: PRK05298
990282002449	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
990282002450	ATP binding site [chemical binding]; other site
990282002451	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
990282002452	nucleotide binding region [chemical binding]; other site
990282002453	ATP-binding site [chemical binding]; other site
990282002454	Ultra-violet resistance protein B; Region: UvrB; pfam12344
990282002455	UvrB/uvrC motif; Region: UVR; pfam02151
990282002456	E3 ubiquitin-protein ligase SlrP; Provisional; Region: PRK15370
990282002457	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
990282002458	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
990282002459	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
990282002460	Leucine-rich repeats; other site
990282002461	Substrate binding site [chemical binding]; other site
990282002462	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
990282002463	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
990282002464	putative substrate binding pocket [chemical binding]; other site
990282002465	dimer interface [polypeptide binding]; other site
990282002466	phosphate binding site [ion binding]; other site
990282002467	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
990282002468	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282002469	FeS/SAM binding site; other site
990282002470	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
990282002471	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
990282002472	MPT binding site; other site
990282002473	trimer interface [polypeptide binding]; other site
990282002474	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
990282002475	trimer interface [polypeptide binding]; other site
990282002476	dimer interface [polypeptide binding]; other site
990282002477	putative active site [active]
990282002478	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
990282002479	MoaE interaction surface [polypeptide binding]; other site
990282002480	MoeB interaction surface [polypeptide binding]; other site
990282002481	thiocarboxylated glycine; other site
990282002482	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
990282002483	MoaE homodimer interface [polypeptide binding]; other site
990282002484	MoaD interaction [polypeptide binding]; other site
990282002485	active site residues [active]
990282002486	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
990282002487	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
990282002488	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
990282002489	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
990282002490	Predicted integral membrane protein [Function unknown]; Region: COG0392
990282002491	cardiolipin synthase 2; Provisional; Region: PRK11263
990282002492	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
990282002493	putative active site [active]
990282002494	catalytic site [active]
990282002495	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
990282002496	putative active site [active]
990282002497	catalytic site [active]
990282002498	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
990282002499	putative catalytic site [active]
990282002500	putative metal binding site [ion binding]; other site
990282002501	putative phosphate binding site [ion binding]; other site
990282002502	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
990282002503	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
990282002504	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
990282002505	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
990282002506	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
990282002507	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
990282002508	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
990282002509	Walker A/P-loop; other site
990282002510	ATP binding site [chemical binding]; other site
990282002511	Q-loop/lid; other site
990282002512	ABC transporter signature motif; other site
990282002513	Walker B; other site
990282002514	D-loop; other site
990282002515	H-loop/switch region; other site
990282002516	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
990282002517	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
990282002518	Walker A/P-loop; other site
990282002519	ATP binding site [chemical binding]; other site
990282002520	Q-loop/lid; other site
990282002521	ABC transporter signature motif; other site
990282002522	Walker B; other site
990282002523	D-loop; other site
990282002524	H-loop/switch region; other site
990282002525	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
990282002526	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
990282002527	HlyD family secretion protein; Region: HlyD_3; pfam13437
990282002528	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
990282002529	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
990282002530	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
990282002531	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
990282002532	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
990282002533	ATP binding site [chemical binding]; other site
990282002534	Mg++ binding site [ion binding]; other site
990282002535	motif III; other site
990282002536	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
990282002537	nucleotide binding region [chemical binding]; other site
990282002538	ATP-binding site [chemical binding]; other site
990282002539	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
990282002540	DEAD_2; Region: DEAD_2; pfam06733
990282002541	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
990282002542	glycosyl transferase family protein; Provisional; Region: PRK08136
990282002543	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
990282002544	hypothetical protein; Provisional; Region: PRK10259
990282002545	hypothetical protein; Provisional; Region: PRK11019
990282002546	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
990282002547	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
990282002548	putative mechanosensitive channel protein; Provisional; Region: PRK11465
990282002549	Mechanosensitive ion channel; Region: MS_channel; pfam00924
990282002550	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
990282002551	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
990282002552	Walker A/P-loop; other site
990282002553	ATP binding site [chemical binding]; other site
990282002554	Q-loop/lid; other site
990282002555	ABC transporter signature motif; other site
990282002556	Walker B; other site
990282002557	D-loop; other site
990282002558	H-loop/switch region; other site
990282002559	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
990282002560	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282002561	dimer interface [polypeptide binding]; other site
990282002562	conserved gate region; other site
990282002563	putative PBP binding loops; other site
990282002564	ABC-ATPase subunit interface; other site
990282002565	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
990282002566	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
990282002567	substrate binding pocket [chemical binding]; other site
990282002568	membrane-bound complex binding site; other site
990282002569	hinge residues; other site
990282002570	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
990282002571	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
990282002572	dimerization interface [polypeptide binding]; other site
990282002573	DPS ferroxidase diiron center [ion binding]; other site
990282002574	ion pore; other site
990282002575	threonine and homoserine efflux system; Provisional; Region: PRK10532
990282002576	EamA-like transporter family; Region: EamA; pfam00892
990282002577	outer membrane protein X; Provisional; Region: ompX; PRK09408
990282002578	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
990282002579	Sulfatase; Region: Sulfatase; pfam00884
990282002580	manganese transport regulator MntR; Provisional; Region: PRK11050
990282002581	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
990282002582	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
990282002583	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
990282002584	transmembrane helices; other site
990282002585	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
990282002586	L,D-transpeptidase; Provisional; Region: PRK10260
990282002587	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
990282002588	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
990282002589	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
990282002590	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282002591	Walker A/P-loop; other site
990282002592	ATP binding site [chemical binding]; other site
990282002593	ABC transporter signature motif; other site
990282002594	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
990282002595	Walker B; other site
990282002596	ABC transporter; Region: ABC_tran_2; pfam12848
990282002597	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
990282002598	Domain of unknown function (DUF4261); Region: DUF4261; pfam14080
990282002599	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
990282002600	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
990282002601	motif II; other site
990282002602	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282002603	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
990282002604	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
990282002605	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282002606	active site
990282002607	motif I; other site
990282002608	motif II; other site
990282002609	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282002610	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
990282002611	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
990282002612	dimer interface [polypeptide binding]; other site
990282002613	active site
990282002614	glycine loop; other site
990282002615	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
990282002616	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282002617	FeS/SAM binding site; other site
990282002618	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
990282002619	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
990282002620	ATP binding site [chemical binding]; other site
990282002621	substrate interface [chemical binding]; other site
990282002622	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
990282002623	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
990282002624	dimer interface [polypeptide binding]; other site
990282002625	putative functional site; other site
990282002626	putative MPT binding site; other site
990282002627	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
990282002628	catalytic nucleophile [active]
990282002629	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
990282002630	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
990282002631	Walker A/P-loop; other site
990282002632	ATP binding site [chemical binding]; other site
990282002633	Q-loop/lid; other site
990282002634	ABC transporter signature motif; other site
990282002635	Walker B; other site
990282002636	D-loop; other site
990282002637	H-loop/switch region; other site
990282002638	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
990282002639	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
990282002640	Walker A/P-loop; other site
990282002641	ATP binding site [chemical binding]; other site
990282002642	Q-loop/lid; other site
990282002643	ABC transporter signature motif; other site
990282002644	Walker B; other site
990282002645	D-loop; other site
990282002646	H-loop/switch region; other site
990282002647	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
990282002648	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
990282002649	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
990282002650	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
990282002651	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282002652	dimer interface [polypeptide binding]; other site
990282002653	conserved gate region; other site
990282002654	putative PBP binding loops; other site
990282002655	ABC-ATPase subunit interface; other site
990282002656	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
990282002657	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
990282002658	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282002659	dimer interface [polypeptide binding]; other site
990282002660	conserved gate region; other site
990282002661	putative PBP binding loops; other site
990282002662	ABC-ATPase subunit interface; other site
990282002663	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
990282002664	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
990282002665	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282002666	FeS/SAM binding site; other site
990282002667	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
990282002668	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
990282002669	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
990282002670	Ligand binding site [chemical binding]; other site
990282002671	Electron transfer flavoprotein domain; Region: ETF; pfam01012
990282002672	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
990282002673	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
990282002674	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
990282002675	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
990282002676	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
990282002677	active site
990282002678	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
990282002679	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
990282002680	Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187
990282002681	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
990282002682	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282002683	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282002684	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_1; cd08421
990282002685	putative dimerization interface [polypeptide binding]; other site
990282002686	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
990282002687	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
990282002688	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
990282002689	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
990282002690	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
990282002691	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
990282002692	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
990282002693	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
990282002694	putative C-terminal domain interface [polypeptide binding]; other site
990282002695	putative GSH binding site (G-site) [chemical binding]; other site
990282002696	putative dimer interface [polypeptide binding]; other site
990282002697	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
990282002698	putative N-terminal domain interface [polypeptide binding]; other site
990282002699	putative dimer interface [polypeptide binding]; other site
990282002700	putative substrate binding pocket (H-site) [chemical binding]; other site
990282002701	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
990282002702	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
990282002703	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
990282002704	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
990282002705	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
990282002706	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
990282002707	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
990282002708	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
990282002709	active site
990282002710	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
990282002711	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282002712	putative substrate translocation pore; other site
990282002713	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
990282002714	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282002715	active site
990282002716	motif I; other site
990282002717	motif II; other site
990282002718	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282002719	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282002720	putative substrate translocation pore; other site
990282002721	Major Facilitator Superfamily; Region: MFS_1; pfam07690
990282002722	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3226
990282002723	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
990282002724	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
990282002725	putative transporter; Provisional; Region: PRK04972
990282002726	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
990282002727	TrkA-C domain; Region: TrkA_C; pfam02080
990282002728	TrkA-C domain; Region: TrkA_C; pfam02080
990282002729	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
990282002730	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
990282002731	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
990282002732	GSH binding site [chemical binding]; other site
990282002733	catalytic residues [active]
990282002734	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
990282002735	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
990282002736	dimer interface [polypeptide binding]; other site
990282002737	FMN binding site [chemical binding]; other site
990282002738	NADPH bind site [chemical binding]; other site
990282002739	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
990282002740	RimK-like ATP-grasp domain; Region: RimK; pfam08443
990282002741	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
990282002742	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
990282002743	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
990282002744	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
990282002745	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282002746	Walker A/P-loop; other site
990282002747	ATP binding site [chemical binding]; other site
990282002748	Q-loop/lid; other site
990282002749	ABC transporter signature motif; other site
990282002750	Walker B; other site
990282002751	D-loop; other site
990282002752	H-loop/switch region; other site
990282002753	TOBE domain; Region: TOBE_2; pfam08402
990282002754	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
990282002755	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282002756	dimer interface [polypeptide binding]; other site
990282002757	conserved gate region; other site
990282002758	putative PBP binding loops; other site
990282002759	ABC-ATPase subunit interface; other site
990282002760	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
990282002761	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282002762	dimer interface [polypeptide binding]; other site
990282002763	conserved gate region; other site
990282002764	putative PBP binding loops; other site
990282002765	ABC-ATPase subunit interface; other site
990282002766	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
990282002767	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
990282002768	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282002769	S-adenosylmethionine binding site [chemical binding]; other site
990282002770	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
990282002771	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
990282002772	active site
990282002773	P-loop; other site
990282002774	phosphorylation site [posttranslational modification]
990282002775	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
990282002776	Sulfatase; Region: Sulfatase; cl17466
990282002777	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
990282002778	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
990282002779	substrate binding pocket [chemical binding]; other site
990282002780	membrane-bound complex binding site; other site
990282002781	hinge residues; other site
990282002782	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282002783	dimer interface [polypeptide binding]; other site
990282002784	conserved gate region; other site
990282002785	putative PBP binding loops; other site
990282002786	ABC-ATPase subunit interface; other site
990282002787	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
990282002788	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282002789	dimer interface [polypeptide binding]; other site
990282002790	conserved gate region; other site
990282002791	putative PBP binding loops; other site
990282002792	ABC-ATPase subunit interface; other site
990282002793	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
990282002794	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
990282002795	substrate binding pocket [chemical binding]; other site
990282002796	membrane-bound complex binding site; other site
990282002797	hinge residues; other site
990282002798	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
990282002799	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282002800	Walker A/P-loop; other site
990282002801	ATP binding site [chemical binding]; other site
990282002802	Q-loop/lid; other site
990282002803	ABC transporter signature motif; other site
990282002804	Walker B; other site
990282002805	D-loop; other site
990282002806	H-loop/switch region; other site
990282002807	putative lipoprotein; Provisional; Region: PRK10533
990282002808	hypothetical protein; Provisional; Region: PRK02877
990282002809	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
990282002810	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
990282002811	amidase catalytic site [active]
990282002812	Zn binding residues [ion binding]; other site
990282002813	substrate binding site [chemical binding]; other site
990282002814	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
990282002815	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
990282002816	NAD(P) binding site [chemical binding]; other site
990282002817	active site
990282002818	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
990282002819	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
990282002820	putative NAD(P) binding site [chemical binding]; other site
990282002821	putative active site [active]
990282002822	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
990282002823	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
990282002824	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
990282002825	tetramer interface [polypeptide binding]; other site
990282002826	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282002827	catalytic residue [active]
990282002828	pyruvate dehydrogenase; Provisional; Region: PRK09124
990282002829	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
990282002830	PYR/PP interface [polypeptide binding]; other site
990282002831	dimer interface [polypeptide binding]; other site
990282002832	tetramer interface [polypeptide binding]; other site
990282002833	TPP binding site [chemical binding]; other site
990282002834	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
990282002835	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
990282002836	TPP-binding site [chemical binding]; other site
990282002837	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
990282002838	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
990282002839	FAD binding pocket [chemical binding]; other site
990282002840	FAD binding motif [chemical binding]; other site
990282002841	phosphate binding motif [ion binding]; other site
990282002842	beta-alpha-beta structure motif; other site
990282002843	NAD binding pocket [chemical binding]; other site
990282002844	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
990282002845	catalytic loop [active]
990282002846	iron binding site [ion binding]; other site
990282002847	hybrid cluster protein; Provisional; Region: PRK05290
990282002848	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
990282002849	ACS interaction site; other site
990282002850	CODH interaction site; other site
990282002851	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
990282002852	hybrid metal cluster; other site
990282002853	Predicted membrane protein [Function unknown]; Region: COG2431
990282002854	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
990282002855	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
990282002856	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
990282002857	putative active site [active]
990282002858	putative metal-binding site [ion binding]; other site
990282002859	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
990282002860	macrolide transporter subunit MacA; Provisional; Region: PRK11578
990282002861	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
990282002862	HlyD family secretion protein; Region: HlyD_3; pfam13437
990282002863	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
990282002864	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
990282002865	Walker A/P-loop; other site
990282002866	ATP binding site [chemical binding]; other site
990282002867	Q-loop/lid; other site
990282002868	ABC transporter signature motif; other site
990282002869	Walker B; other site
990282002870	D-loop; other site
990282002871	H-loop/switch region; other site
990282002872	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
990282002873	FtsX-like permease family; Region: FtsX; pfam02687
990282002874	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
990282002875	DNA-binding site [nucleotide binding]; DNA binding site
990282002876	RNA-binding motif; other site
990282002877	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
990282002878	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
990282002879	Clp amino terminal domain; Region: Clp_N; pfam02861
990282002880	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282002881	Walker A motif; other site
990282002882	ATP binding site [chemical binding]; other site
990282002883	Walker B motif; other site
990282002884	arginine finger; other site
990282002885	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282002886	Walker A motif; other site
990282002887	ATP binding site [chemical binding]; other site
990282002888	Walker B motif; other site
990282002889	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
990282002890	Transposase IS200 like; Region: Y1_Tnp; pfam01797
990282002891	Integrase core domain; Region: rve; pfam00665
990282002892	Integrase core domain; Region: rve_3; pfam13683
990282002893	Helix-turn-helix domain; Region: HTH_28; pfam13518
990282002894	Isochorismatase family; Region: Isochorismatase; pfam00857
990282002895	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
990282002896	catalytic triad [active]
990282002897	dimer interface [polypeptide binding]; other site
990282002898	conserved cis-peptide bond; other site
990282002899	Pirin-related protein [General function prediction only]; Region: COG1741
990282002900	Pirin; Region: Pirin; pfam02678
990282002901	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
990282002902	LysR family transcriptional regulator; Provisional; Region: PRK14997
990282002903	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282002904	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
990282002905	putative effector binding pocket; other site
990282002906	putative dimerization interface [polypeptide binding]; other site
990282002907	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
990282002908	rRNA binding site [nucleotide binding]; other site
990282002909	predicted 30S ribosome binding site; other site
990282002910	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
990282002911	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
990282002912	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
990282002913	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282002914	Walker A/P-loop; other site
990282002915	ATP binding site [chemical binding]; other site
990282002916	Q-loop/lid; other site
990282002917	ABC transporter signature motif; other site
990282002918	Walker B; other site
990282002919	D-loop; other site
990282002920	H-loop/switch region; other site
990282002921	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
990282002922	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
990282002923	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282002924	Walker A/P-loop; other site
990282002925	ATP binding site [chemical binding]; other site
990282002926	Q-loop/lid; other site
990282002927	ABC transporter signature motif; other site
990282002928	Walker B; other site
990282002929	D-loop; other site
990282002930	H-loop/switch region; other site
990282002931	thioredoxin reductase; Provisional; Region: PRK10262
990282002932	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
990282002933	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
990282002934	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
990282002935	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
990282002936	putative DNA binding site [nucleotide binding]; other site
990282002937	putative Zn2+ binding site [ion binding]; other site
990282002938	AsnC family; Region: AsnC_trans_reg; pfam01037
990282002939	periplasmic chaperone LolA; Region: lolA; TIGR00547
990282002940	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
990282002941	recombination factor protein RarA; Reviewed; Region: PRK13342
990282002942	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282002943	Walker A motif; other site
990282002944	ATP binding site [chemical binding]; other site
990282002945	Walker B motif; other site
990282002946	arginine finger; other site
990282002947	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
990282002948	seryl-tRNA synthetase; Provisional; Region: PRK05431
990282002949	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
990282002950	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
990282002951	dimer interface [polypeptide binding]; other site
990282002952	active site
990282002953	motif 1; other site
990282002954	motif 2; other site
990282002955	motif 3; other site
990282002956	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
990282002957	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
990282002958	putative [Fe4-S4] binding site [ion binding]; other site
990282002959	putative molybdopterin cofactor binding site [chemical binding]; other site
990282002960	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
990282002961	putative molybdopterin cofactor binding site; other site
990282002962	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
990282002963	4Fe-4S binding domain; Region: Fer4; pfam00037
990282002964	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
990282002965	putative MFS family transporter protein; Provisional; Region: PRK03633
990282002966	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282002967	putative substrate translocation pore; other site
990282002968	inner membrane transporter YjeM; Provisional; Region: PRK15238
990282002969	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
990282002970	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282002971	FeS/SAM binding site; other site
990282002972	pathogenicity island 1 protein SopD2; Provisional; Region: PRK15380
990282002973	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
990282002974	Pyruvate formate lyase 1; Region: PFL1; cd01678
990282002975	coenzyme A binding site [chemical binding]; other site
990282002976	active site
990282002977	catalytic residues [active]
990282002978	glycine loop; other site
990282002979	formate transporter; Provisional; Region: PRK10805
990282002980	uncharacterized domain; Region: TIGR00702
990282002981	YcaO-like family; Region: YcaO; pfam02624
990282002982	Predicted membrane protein [Function unknown]; Region: COG2323
990282002983	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
990282002984	homodimer interface [polypeptide binding]; other site
990282002985	substrate-cofactor binding pocket; other site
990282002986	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282002987	catalytic residue [active]
990282002988	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
990282002989	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
990282002990	hinge; other site
990282002991	active site
990282002992	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
990282002993	cytidylate kinase; Provisional; Region: cmk; PRK00023
990282002994	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
990282002995	CMP-binding site; other site
990282002996	The sites determining sugar specificity; other site
990282002997	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
990282002998	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
990282002999	RNA binding site [nucleotide binding]; other site
990282003000	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
990282003001	RNA binding site [nucleotide binding]; other site
990282003002	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
990282003003	RNA binding site [nucleotide binding]; other site
990282003004	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
990282003005	RNA binding site [nucleotide binding]; other site
990282003006	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
990282003007	RNA binding site [nucleotide binding]; other site
990282003008	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
990282003009	IHF dimer interface [polypeptide binding]; other site
990282003010	IHF - DNA interface [nucleotide binding]; other site
990282003011	ComEC family competence protein; Provisional; Region: PRK11539
990282003012	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
990282003013	Competence protein; Region: Competence; pfam03772
990282003014	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
990282003015	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
990282003016	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
990282003017	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
990282003018	Walker A/P-loop; other site
990282003019	ATP binding site [chemical binding]; other site
990282003020	Q-loop/lid; other site
990282003021	ABC transporter signature motif; other site
990282003022	Walker B; other site
990282003023	D-loop; other site
990282003024	H-loop/switch region; other site
990282003025	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
990282003026	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
990282003027	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
990282003028	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
990282003029	hypothetical protein; Provisional; Region: PRK11827
990282003030	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
990282003031	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
990282003032	Ligand binding site; other site
990282003033	oligomer interface; other site
990282003034	hypothetical protein; Provisional; Region: PRK10593
990282003035	Uncharacterized conserved protein [Function unknown]; Region: COG1434
990282003036	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
990282003037	putative active site [active]
990282003038	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
990282003039	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282003040	S-adenosylmethionine binding site [chemical binding]; other site
990282003041	condesin subunit F; Provisional; Region: PRK05260
990282003042	condesin subunit E; Provisional; Region: PRK05256
990282003043	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
990282003044	P-loop containing region of AAA domain; Region: AAA_29; cl17516
990282003045	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
990282003046	murein L,D-transpeptidase; Provisional; Region: PRK10594
990282003047	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
990282003048	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
990282003049	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
990282003050	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
990282003051	Peptidase M15; Region: Peptidase_M15_3; cl01194
990282003052	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
990282003053	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
990282003054	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
990282003055	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282003056	homodimer interface [polypeptide binding]; other site
990282003057	catalytic residue [active]
990282003058	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
990282003059	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
990282003060	trimer interface [polypeptide binding]; other site
990282003061	eyelet of channel; other site
990282003062	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
990282003063	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
990282003064	putative dimer interface [polypeptide binding]; other site
990282003065	putative anticodon binding site; other site
990282003066	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
990282003067	homodimer interface [polypeptide binding]; other site
990282003068	motif 1; other site
990282003069	motif 2; other site
990282003070	active site
990282003071	motif 3; other site
990282003072	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
990282003073	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
990282003074	putative DNA binding site [nucleotide binding]; other site
990282003075	putative Zn2+ binding site [ion binding]; other site
990282003076	AsnC family; Region: AsnC_trans_reg; pfam01037
990282003077	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
990282003078	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
990282003079	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
990282003080	catalytic residue [active]
990282003081	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
990282003082	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
990282003083	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
990282003084	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
990282003085	active site
990282003086	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
990282003087	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
990282003088	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
990282003089	Int/Topo IB signature motif; other site
990282003090	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
990282003091	Protein of unknown function (DUF4060); Region: DUF4060; pfam13269
990282003092	RecT family; Region: RecT; pfam03837
990282003093	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
990282003094	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
990282003095	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
990282003096	non-specific DNA binding site [nucleotide binding]; other site
990282003097	salt bridge; other site
990282003098	sequence-specific DNA binding site [nucleotide binding]; other site
990282003099	Bacteriophage CII protein; Region: Phage_CII; pfam05269
990282003100	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
990282003101	primosomal protein DnaI; Provisional; Region: PRK02854
990282003102	putative replication protein; Provisional; Region: PRK12377
990282003103	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282003104	Walker A motif; other site
990282003105	ATP binding site [chemical binding]; other site
990282003106	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
990282003107	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
990282003108	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
990282003109	DinI-like family; Region: DinI; pfam06183
990282003110	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
990282003111	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
990282003112	Antitermination protein; Region: Antiterm; pfam03589
990282003113	Antitermination protein; Region: Antiterm; pfam03589
990282003114	PipA protein; Region: PipA; pfam07108
990282003115	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
990282003116	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
990282003117	catalytic residues [active]
990282003118	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
990282003119	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
990282003120	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
990282003121	Domain of unknown function (DUF1859); Region: DUF1859; pfam08948
990282003122	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
990282003123	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
990282003124	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
990282003125	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
990282003126	oligomer interface [polypeptide binding]; other site
990282003127	active site residues [active]
990282003128	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; cl01826
990282003129	Uncharacterized conserved protein [Function unknown]; Region: COG5471
990282003130	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; pfam13856
990282003131	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
990282003132	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
990282003133	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
990282003134	phage minor tail protein G; Region: phage_lambda_G; TIGR01674
990282003135	phage tail assembly protein T; Region: phage_lam_T; TIGR01715
990282003136	Phage-related minor tail protein [Function unknown]; Region: COG5281
990282003137	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
990282003138	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
990282003139	Phage-related protein [Function unknown]; Region: COG4718
990282003140	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
990282003141	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
990282003142	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
990282003143	E-class dimer interface [polypeptide binding]; other site
990282003144	P-class dimer interface [polypeptide binding]; other site
990282003145	active site
990282003146	Cu2+ binding site [ion binding]; other site
990282003147	Zn2+ binding site [ion binding]; other site
990282003148	Phage-related protein [Function unknown]; Region: gp18; COG4672
990282003149	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
990282003150	MPN+ (JAMM) motif; other site
990282003151	Zinc-binding site [ion binding]; other site
990282003152	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
990282003153	NlpC/P60 family; Region: NLPC_P60; cl17555
990282003154	Phage-related protein, tail component [Function unknown]; Region: COG4723
990282003155	Phage-related protein, tail component [Function unknown]; Region: COG4733
990282003156	Putative phage tail protein; Region: Phage-tail_3; pfam13550
990282003157	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
990282003158	Interdomain contacts; other site
990282003159	Cytokine receptor motif; other site
990282003160	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
990282003161	Fibronectin type III protein; Region: DUF3672; pfam12421
990282003162	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
990282003163	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
990282003164	Phage Tail Collar Domain; Region: Collar; pfam07484
990282003165	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
990282003166	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
990282003167	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
990282003168	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
990282003169	hypothetical protein; Provisional; Region: PRK09951
990282003170	DinI-like family; Region: DinI; cl11630
990282003171	aminopeptidase N; Provisional; Region: pepN; PRK14015
990282003172	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
990282003173	active site
990282003174	Zn binding site [ion binding]; other site
990282003175	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
990282003176	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
990282003177	quinone interaction residues [chemical binding]; other site
990282003178	active site
990282003179	catalytic residues [active]
990282003180	FMN binding site [chemical binding]; other site
990282003181	substrate binding site [chemical binding]; other site
990282003182	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
990282003183	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
990282003184	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
990282003185	MOSC domain; Region: MOSC; pfam03473
990282003186	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
990282003187	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
990282003188	catalytic loop [active]
990282003189	iron binding site [ion binding]; other site
990282003190	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
990282003191	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
990282003192	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
990282003193	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282003194	S-adenosylmethionine binding site [chemical binding]; other site
990282003195	ABC transporter ATPase component; Reviewed; Region: PRK11147
990282003196	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282003197	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282003198	Walker A/P-loop; other site
990282003199	Walker A/P-loop; other site
990282003200	ATP binding site [chemical binding]; other site
990282003201	ATP binding site [chemical binding]; other site
990282003202	Q-loop/lid; other site
990282003203	Q-loop/lid; other site
990282003204	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
990282003205	ABC transporter signature motif; other site
990282003206	Walker B; other site
990282003207	D-loop; other site
990282003208	ABC transporter; Region: ABC_tran_2; pfam12848
990282003209	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
990282003210	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
990282003211	Paraquat-inducible protein A; Region: PqiA; pfam04403
990282003212	Paraquat-inducible protein A; Region: PqiA; pfam04403
990282003213	paraquat-inducible protein B; Provisional; Region: PRK10807
990282003214	mce related protein; Region: MCE; pfam02470
990282003215	mce related protein; Region: MCE; pfam02470
990282003216	mce related protein; Region: MCE; pfam02470
990282003217	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
990282003218	Protein of unknown function (DUF330); Region: DUF330; pfam03886
990282003219	ribosome modulation factor; Provisional; Region: PRK14563
990282003220	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
990282003221	active site 1 [active]
990282003222	dimer interface [polypeptide binding]; other site
990282003223	active site 2 [active]
990282003224	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
990282003225	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
990282003226	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
990282003227	outer membrane protein A; Reviewed; Region: PRK10808
990282003228	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
990282003229	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
990282003230	ligand binding site [chemical binding]; other site
990282003231	cell division inhibitor SulA; Region: sula; TIGR00623
990282003232	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
990282003233	TfoX C-terminal domain; Region: TfoX_C; pfam04994
990282003234	TIGR01666 family membrane protein; Region: YCCS
990282003235	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
990282003236	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
990282003237	Predicted membrane protein [Function unknown]; Region: COG3304
990282003238	Domain of unknown function (DUF307); Region: DUF307; pfam03733
990282003239	Domain of unknown function (DUF307); Region: DUF307; pfam03733
990282003240	DNA helicase IV; Provisional; Region: helD; PRK11054
990282003241	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
990282003242	Part of AAA domain; Region: AAA_19; pfam13245
990282003243	Family description; Region: UvrD_C_2; pfam13538
990282003244	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
990282003245	active site
990282003246	dimer interfaces [polypeptide binding]; other site
990282003247	catalytic residues [active]
990282003248	hypothetical protein; Provisional; Region: PRK03641
990282003249	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
990282003250	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
990282003251	heat shock protein HspQ; Provisional; Region: PRK14129
990282003252	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
990282003253	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
990282003254	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
990282003255	putative RNA binding site [nucleotide binding]; other site
990282003256	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282003257	S-adenosylmethionine binding site [chemical binding]; other site
990282003258	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
990282003259	substrate binding site [chemical binding]; other site
990282003260	Cupin domain; Region: Cupin_2; cl17218
990282003261	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
990282003262	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282003263	acylphosphatase; Provisional; Region: PRK14426
990282003264	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
990282003265	sulfur transfer protein TusE; Provisional; Region: PRK11508
990282003266	YccA-like proteins; Region: YccA_like; cd10433
990282003267	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
990282003268	PipA protein; Region: PipA; pfam07108
990282003269	secreted effector protein PipB; Provisional; Region: PRK15197
990282003270	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
990282003271	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
990282003272	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
990282003273	type III secretion chaperone protein SigE; Provisional; Region: PRK15202
990282003274	inositol phosphate phosphatase SopB; Provisional; Region: PRK15378
990282003275	Enterobacterial virulence protein IpgD; Region: IpgD; pfam05925
990282003276	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
990282003277	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
990282003278	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
990282003279	HAMP domain; Region: HAMP; pfam00672
990282003280	dimerization interface [polypeptide binding]; other site
990282003281	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282003282	dimer interface [polypeptide binding]; other site
990282003283	phosphorylation site [posttranslational modification]
990282003284	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282003285	ATP binding site [chemical binding]; other site
990282003286	Mg2+ binding site [ion binding]; other site
990282003287	G-X-G motif; other site
990282003288	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
990282003289	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282003290	active site
990282003291	phosphorylation site [posttranslational modification]
990282003292	intermolecular recognition site; other site
990282003293	dimerization interface [polypeptide binding]; other site
990282003294	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
990282003295	DNA binding site [nucleotide binding]
990282003296	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
990282003297	active site
990282003298	homotetramer interface [polypeptide binding]; other site
990282003299	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
990282003300	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
990282003301	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
990282003302	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
990282003303	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
990282003304	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
990282003305	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
990282003306	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
990282003307	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
990282003308	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
990282003309	NAD binding site [chemical binding]; other site
990282003310	catalytic residues [active]
990282003311	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
990282003312	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
990282003313	putative active site [active]
990282003314	putative metal binding site [ion binding]; other site
990282003315	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
990282003316	putative substrate binding pocket [chemical binding]; other site
990282003317	trimer interface [polypeptide binding]; other site
990282003318	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
990282003319	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
990282003320	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282003321	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
990282003322	putative substrate translocation pore; other site
990282003323	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
990282003324	Cupin domain; Region: Cupin_2; pfam07883
990282003325	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282003326	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
990282003327	anti-adapter protein IraM; Provisional; Region: PRK09919
990282003328	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
990282003329	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
990282003330	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
990282003331	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
990282003332	HSP70 interaction site [polypeptide binding]; other site
990282003333	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
990282003334	substrate binding site [polypeptide binding]; other site
990282003335	dimer interface [polypeptide binding]; other site
990282003336	Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4233
990282003337	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
990282003338	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
990282003339	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
990282003340	DsbD alpha interface [polypeptide binding]; other site
990282003341	catalytic residues [active]
990282003342	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
990282003343	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
990282003344	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
990282003345	catalytic residues [active]
990282003346	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
990282003347	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
990282003348	catalytic residues [active]
990282003349	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
990282003350	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
990282003351	catalytic core [active]
990282003352	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
990282003353	hypothetical protein; Provisional; Region: PRK10174
990282003354	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
990282003355	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
990282003356	General stress protein [General function prediction only]; Region: GsiB; COG3729
990282003357	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
990282003358	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
990282003359	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
990282003360	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
990282003361	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
990282003362	Predicted transcriptional regulator [Transcription]; Region: COG3905
990282003363	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
990282003364	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
990282003365	Glutamate binding site [chemical binding]; other site
990282003366	NAD binding site [chemical binding]; other site
990282003367	catalytic residues [active]
990282003368	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
990282003369	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
990282003370	Na binding site [ion binding]; other site
990282003371	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
990282003372	hypothetical protein; Provisional; Region: PRK10536
990282003373	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
990282003374	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
990282003375	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
990282003376	putative active site [active]
990282003377	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
990282003378	Na binding site [ion binding]; other site
990282003379	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
990282003380	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
990282003381	putative active site cavity [active]
990282003382	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
990282003383	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
990282003384	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
990282003385	putative sialic acid transporter; Provisional; Region: PRK12307
990282003386	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282003387	putative substrate translocation pore; other site
990282003388	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
990282003389	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
990282003390	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
990282003391	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
990282003392	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
990282003393	putative ligand binding site [chemical binding]; other site
990282003394	NAD binding site [chemical binding]; other site
990282003395	dimerization interface [polypeptide binding]; other site
990282003396	catalytic site [active]
990282003397	putative hydrolase; Validated; Region: PRK09248
990282003398	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
990282003399	active site
990282003400	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
990282003401	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
990282003402	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
990282003403	curli assembly protein CsgF; Provisional; Region: PRK10050
990282003404	curli assembly protein CsgE; Provisional; Region: PRK10386
990282003405	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
990282003406	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282003407	DNA binding residues [nucleotide binding]
990282003408	dimerization interface [polypeptide binding]; other site
990282003409	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
990282003410	Curlin associated repeat; Region: Curlin_rpt; pfam07012
990282003411	Curlin associated repeat; Region: Curlin_rpt; pfam07012
990282003412	major curlin subunit; Provisional; Region: csgA; PRK10051
990282003413	Curlin associated repeat; Region: Curlin_rpt; pfam07012
990282003414	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
990282003415	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
990282003416	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
990282003417	putative ADP-ribose binding site [chemical binding]; other site
990282003418	putative active site [active]
990282003419	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
990282003420	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
990282003421	putative active site [active]
990282003422	catalytic site [active]
990282003423	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
990282003424	putative active site [active]
990282003425	catalytic site [active]
990282003426	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
990282003427	Acyltransferase family; Region: Acyl_transf_3; pfam01757
990282003428	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
990282003429	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
990282003430	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
990282003431	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
990282003432	Ligand binding site; other site
990282003433	DXD motif; other site
990282003434	lipoprotein; Provisional; Region: PRK10175
990282003435	secY/secA suppressor protein; Provisional; Region: PRK11467
990282003436	drug efflux system protein MdtG; Provisional; Region: PRK09874
990282003437	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282003438	putative substrate translocation pore; other site
990282003439	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
990282003440	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
990282003441	putative acyl-acceptor binding pocket; other site
990282003442	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
990282003443	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
990282003444	active site residue [active]
990282003445	hypothetical protein; Provisional; Region: PRK03757
990282003446	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
990282003447	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
990282003448	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
990282003449	hydroxyglutarate oxidase; Provisional; Region: PRK11728
990282003450	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
990282003451	DNA damage-inducible protein I; Provisional; Region: PRK10597
990282003452	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
990282003453	active site
990282003454	substrate binding pocket [chemical binding]; other site
990282003455	dimer interface [polypeptide binding]; other site
990282003456	lipoprotein; Provisional; Region: PRK10598
990282003457	glutaredoxin 2; Provisional; Region: PRK10387
990282003458	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
990282003459	C-terminal domain interface [polypeptide binding]; other site
990282003460	GSH binding site (G-site) [chemical binding]; other site
990282003461	catalytic residues [active]
990282003462	putative dimer interface [polypeptide binding]; other site
990282003463	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
990282003464	N-terminal domain interface [polypeptide binding]; other site
990282003465	multidrug resistance protein MdtH; Provisional; Region: PRK11646
990282003466	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282003467	putative substrate translocation pore; other site
990282003468	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
990282003469	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
990282003470	hypothetical protein; Provisional; Region: PRK11239
990282003471	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
990282003472	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
990282003473	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
990282003474	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
990282003475	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
990282003476	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
990282003477	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
990282003478	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
990282003479	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
990282003480	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
990282003481	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
990282003482	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
990282003483	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
990282003484	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
990282003485	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
990282003486	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
990282003487	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
990282003488	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
990282003489	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
990282003490	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
990282003491	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
990282003492	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
990282003493	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
990282003494	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
990282003495	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
990282003496	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
990282003497	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
990282003498	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
990282003499	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
990282003500	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
990282003501	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
990282003502	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
990282003503	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
990282003504	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
990282003505	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
990282003506	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
990282003507	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
990282003508	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
990282003509	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
990282003510	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
990282003511	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
990282003512	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
990282003513	homodimer interface [polypeptide binding]; other site
990282003514	oligonucleotide binding site [chemical binding]; other site
990282003515	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
990282003516	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
990282003517	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
990282003518	RNA binding surface [nucleotide binding]; other site
990282003519	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
990282003520	active site
990282003521	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
990282003522	Maf-like protein; Region: Maf; pfam02545
990282003523	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
990282003524	active site
990282003525	dimer interface [polypeptide binding]; other site
990282003526	hypothetical protein; Provisional; Region: PRK11193
990282003527	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
990282003528	putative phosphate acyltransferase; Provisional; Region: PRK05331
990282003529	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
990282003530	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
990282003531	dimer interface [polypeptide binding]; other site
990282003532	active site
990282003533	CoA binding pocket [chemical binding]; other site
990282003534	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
990282003535	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
990282003536	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
990282003537	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
990282003538	NAD(P) binding site [chemical binding]; other site
990282003539	homotetramer interface [polypeptide binding]; other site
990282003540	homodimer interface [polypeptide binding]; other site
990282003541	active site
990282003542	acyl carrier protein; Provisional; Region: acpP; PRK00982
990282003543	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
990282003544	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
990282003545	dimer interface [polypeptide binding]; other site
990282003546	active site
990282003547	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
990282003548	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
990282003549	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282003550	catalytic residue [active]
990282003551	conserved hypothetical protein, YceG family; Region: TIGR00247
990282003552	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
990282003553	dimerization interface [polypeptide binding]; other site
990282003554	thymidylate kinase; Validated; Region: tmk; PRK00698
990282003555	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
990282003556	TMP-binding site; other site
990282003557	ATP-binding site [chemical binding]; other site
990282003558	DNA polymerase III subunit delta'; Validated; Region: PRK07993
990282003559	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
990282003560	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
990282003561	active site
990282003562	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
990282003563	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
990282003564	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
990282003565	active site turn [active]
990282003566	phosphorylation site [posttranslational modification]
990282003567	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
990282003568	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
990282003569	N-terminal plug; other site
990282003570	ligand-binding site [chemical binding]; other site
990282003571	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
990282003572	nucleotide binding site/active site [active]
990282003573	HIT family signature motif; other site
990282003574	catalytic residue [active]
990282003575	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
990282003576	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
990282003577	putative dimer interface [polypeptide binding]; other site
990282003578	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
990282003579	thiamine kinase; Region: ycfN_thiK; TIGR02721
990282003580	thiamine kinase; Provisional; Region: thiK; PRK10271
990282003581	substrate binding site [chemical binding]; other site
990282003582	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
990282003583	beta-hexosaminidase; Provisional; Region: PRK05337
990282003584	hypothetical protein; Provisional; Region: PRK04940
990282003585	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
990282003586	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
990282003587	hypothetical protein; Provisional; Region: PRK11280
990282003588	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
990282003589	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
990282003590	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
990282003591	L,D-transpeptidase; Provisional; Region: PRK10190
990282003592	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
990282003593	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
990282003594	transcription-repair coupling factor; Provisional; Region: PRK10689
990282003595	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
990282003596	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
990282003597	ATP binding site [chemical binding]; other site
990282003598	putative Mg++ binding site [ion binding]; other site
990282003599	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
990282003600	nucleotide binding region [chemical binding]; other site
990282003601	ATP-binding site [chemical binding]; other site
990282003602	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
990282003603	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
990282003604	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
990282003605	FtsX-like permease family; Region: FtsX; pfam02687
990282003606	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
990282003607	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
990282003608	Walker A/P-loop; other site
990282003609	ATP binding site [chemical binding]; other site
990282003610	Q-loop/lid; other site
990282003611	ABC transporter signature motif; other site
990282003612	Walker B; other site
990282003613	D-loop; other site
990282003614	H-loop/switch region; other site
990282003615	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
990282003616	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
990282003617	FtsX-like permease family; Region: FtsX; pfam02687
990282003618	fructokinase; Reviewed; Region: PRK09557
990282003619	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
990282003620	nucleotide binding site [chemical binding]; other site
990282003621	NAD-dependent deacetylase; Provisional; Region: PRK00481
990282003622	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
990282003623	NAD+ binding site [chemical binding]; other site
990282003624	substrate binding site [chemical binding]; other site
990282003625	Zn binding site [ion binding]; other site
990282003626	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
990282003627	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
990282003628	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
990282003629	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282003630	dimer interface [polypeptide binding]; other site
990282003631	conserved gate region; other site
990282003632	putative PBP binding loops; other site
990282003633	ABC-ATPase subunit interface; other site
990282003634	Sif protein; Region: Sif; pfam06767
990282003635	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
990282003636	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282003637	dimer interface [polypeptide binding]; other site
990282003638	conserved gate region; other site
990282003639	putative PBP binding loops; other site
990282003640	ABC-ATPase subunit interface; other site
990282003641	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
990282003642	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282003643	Walker A/P-loop; other site
990282003644	ATP binding site [chemical binding]; other site
990282003645	Q-loop/lid; other site
990282003646	ABC transporter signature motif; other site
990282003647	Walker B; other site
990282003648	D-loop; other site
990282003649	H-loop/switch region; other site
990282003650	TOBE domain; Region: TOBE_2; pfam08402
990282003651	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
990282003652	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
990282003653	metal binding site [ion binding]; metal-binding site
990282003654	dimer interface [polypeptide binding]; other site
990282003655	Transposase IS200 like; Region: Y1_Tnp; pfam01797
990282003656	Uncharacterized conserved protein [Function unknown]; Region: COG2850
990282003657	Cupin-like domain; Region: Cupin_8; pfam13621
990282003658	sensor protein PhoQ; Provisional; Region: PRK10815
990282003659	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
990282003660	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
990282003661	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282003662	ATP binding site [chemical binding]; other site
990282003663	Mg2+ binding site [ion binding]; other site
990282003664	G-X-G motif; other site
990282003665	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
990282003666	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282003667	active site
990282003668	phosphorylation site [posttranslational modification]
990282003669	intermolecular recognition site; other site
990282003670	dimerization interface [polypeptide binding]; other site
990282003671	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
990282003672	DNA binding site [nucleotide binding]
990282003673	adenylosuccinate lyase; Provisional; Region: PRK09285
990282003674	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
990282003675	tetramer interface [polypeptide binding]; other site
990282003676	active site
990282003677	putative lysogenization regulator; Reviewed; Region: PRK00218
990282003678	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
990282003679	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
990282003680	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
990282003681	nudix motif; other site
990282003682	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
990282003683	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
990282003684	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
990282003685	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
990282003686	probable active site [active]
990282003687	isocitrate dehydrogenase; Validated; Region: PRK07362
990282003688	isocitrate dehydrogenase; Reviewed; Region: PRK07006
990282003689	Protein of unknown function (DUF3626); Region: DUF3626; pfam12294
990282003690	DinI-like family; Region: DinI; pfam06183
990282003691	Ricin-type beta-trefoil; Region: RICIN; smart00458
990282003692	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
990282003693	putative sugar binding sites [chemical binding]; other site
990282003694	Q-X-W motif; other site
990282003695	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
990282003696	DNA-binding site [nucleotide binding]; DNA binding site
990282003697	RNA-binding motif; other site
990282003698	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
990282003699	lysozyme inhibitor; Provisional; Region: PRK13791
990282003700	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
990282003701	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
990282003702	putative dimer interface [polypeptide binding]; other site
990282003703	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
990282003704	BNR repeat-like domain; Region: BNR_2; pfam13088
990282003705	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
990282003706	TRL-like protein family; Region: TRL; pfam13146
990282003707	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
990282003708	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
990282003709	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
990282003710	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282003711	dimer interface [polypeptide binding]; other site
990282003712	conserved gate region; other site
990282003713	ABC-ATPase subunit interface; other site
990282003714	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
990282003715	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282003716	dimer interface [polypeptide binding]; other site
990282003717	conserved gate region; other site
990282003718	putative PBP binding loops; other site
990282003719	ABC-ATPase subunit interface; other site
990282003720	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
990282003721	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
990282003722	Walker A/P-loop; other site
990282003723	ATP binding site [chemical binding]; other site
990282003724	Q-loop/lid; other site
990282003725	ABC transporter signature motif; other site
990282003726	Walker B; other site
990282003727	D-loop; other site
990282003728	H-loop/switch region; other site
990282003729	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282003730	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
990282003731	Walker A/P-loop; other site
990282003732	ATP binding site [chemical binding]; other site
990282003733	Q-loop/lid; other site
990282003734	ABC transporter signature motif; other site
990282003735	Walker B; other site
990282003736	D-loop; other site
990282003737	H-loop/switch region; other site
990282003738	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
990282003739	Mechanosensitive ion channel; Region: MS_channel; pfam00924
990282003740	Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026
990282003741	dimerization interface [polypeptide binding]; other site
990282003742	zinc/cadmium-binding protein; Provisional; Region: PRK10306
990282003743	aminoglycoside resistance protein; Provisional; Region: PRK13746
990282003744	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
990282003745	active site
990282003746	NTP binding site [chemical binding]; other site
990282003747	metal binding triad [ion binding]; metal-binding site
990282003748	antibiotic binding site [chemical binding]; other site
990282003749	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
990282003750	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282003751	DNA binding residues [nucleotide binding]
990282003752	transcriptional regulator MirA; Provisional; Region: PRK15043
990282003753	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
990282003754	DNA binding residues [nucleotide binding]
990282003755	dimer interface [polypeptide binding]; other site
990282003756	Pleckstrin homology-like domain; Region: PH-like; cl17171
990282003757	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
990282003758	chorismate mutase; Provisional; Region: PRK08055
990282003759	leucine export protein LeuE; Provisional; Region: PRK10958
990282003760	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
990282003761	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
990282003762	hypothetical protein; Provisional; Region: PRK10457
990282003763	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
990282003764	murein hydrolase B; Provisional; Region: PRK10760; cl17906
990282003765	Domain of unknown function (DUF333); Region: DUF333; pfam03891
990282003766	Uncharacterized conserved protein [Function unknown]; Region: COG3189
990282003767	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
990282003768	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282003769	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
990282003770	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282003771	Predicted membrane protein [Function unknown]; Region: COG2707
990282003772	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
990282003773	putative deacylase active site [active]
990282003774	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
990282003775	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
990282003776	metal binding site [ion binding]; metal-binding site
990282003777	active site
990282003778	I-site; other site
990282003779	hypothetical protein; Provisional; Region: PRK05325
990282003780	PrkA family serine protein kinase; Provisional; Region: PRK15455
990282003781	AAA ATPase domain; Region: AAA_16; pfam13191
990282003782	Walker A motif; other site
990282003783	ATP binding site [chemical binding]; other site
990282003784	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
990282003785	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
990282003786	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
990282003787	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282003788	FeS/SAM binding site; other site
990282003789	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
990282003790	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
990282003791	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
990282003792	active site
990282003793	catalytic tetrad [active]
990282003794	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
990282003795	active site
990282003796	phosphate binding residues; other site
990282003797	catalytic residues [active]
990282003798	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
990282003799	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
990282003800	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
990282003801	methionine sulfoxide reductase B; Provisional; Region: PRK00222
990282003802	SelR domain; Region: SelR; pfam01641
990282003803	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
990282003804	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
990282003805	Isochorismatase family; Region: Isochorismatase; pfam00857
990282003806	catalytic triad [active]
990282003807	metal binding site [ion binding]; metal-binding site
990282003808	conserved cis-peptide bond; other site
990282003809	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
990282003810	active site
990282003811	homodimer interface [polypeptide binding]; other site
990282003812	protease 4; Provisional; Region: PRK10949
990282003813	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
990282003814	tandem repeat interface [polypeptide binding]; other site
990282003815	oligomer interface [polypeptide binding]; other site
990282003816	active site residues [active]
990282003817	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
990282003818	tandem repeat interface [polypeptide binding]; other site
990282003819	oligomer interface [polypeptide binding]; other site
990282003820	active site residues [active]
990282003821	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
990282003822	putative FMN binding site [chemical binding]; other site
990282003823	selenophosphate synthetase; Provisional; Region: PRK00943
990282003824	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
990282003825	dimerization interface [polypeptide binding]; other site
990282003826	putative ATP binding site [chemical binding]; other site
990282003827	DNA topoisomerase III; Provisional; Region: PRK07726
990282003828	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
990282003829	active site
990282003830	putative interdomain interaction site [polypeptide binding]; other site
990282003831	putative metal-binding site [ion binding]; other site
990282003832	putative nucleotide binding site [chemical binding]; other site
990282003833	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
990282003834	domain I; other site
990282003835	DNA binding groove [nucleotide binding]
990282003836	phosphate binding site [ion binding]; other site
990282003837	domain II; other site
990282003838	domain III; other site
990282003839	nucleotide binding site [chemical binding]; other site
990282003840	catalytic site [active]
990282003841	domain IV; other site
990282003842	glutamate dehydrogenase; Provisional; Region: PRK09414
990282003843	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
990282003844	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
990282003845	NAD(P) binding site [chemical binding]; other site
990282003846	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
990282003847	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
990282003848	active site
990282003849	8-oxo-dGMP binding site [chemical binding]; other site
990282003850	nudix motif; other site
990282003851	metal binding site [ion binding]; metal-binding site
990282003852	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
990282003853	putative catalytic site [active]
990282003854	putative phosphate binding site [ion binding]; other site
990282003855	active site
990282003856	metal binding site A [ion binding]; metal-binding site
990282003857	DNA binding site [nucleotide binding]
990282003858	putative AP binding site [nucleotide binding]; other site
990282003859	putative metal binding site B [ion binding]; other site
990282003860	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
990282003861	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
990282003862	inhibitor-cofactor binding pocket; inhibition site
990282003863	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282003864	catalytic residue [active]
990282003865	arginine succinyltransferase; Provisional; Region: PRK10456
990282003866	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
990282003867	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
990282003868	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
990282003869	NAD(P) binding site [chemical binding]; other site
990282003870	catalytic residues [active]
990282003871	succinylarginine dihydrolase; Provisional; Region: PRK13281
990282003872	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
990282003873	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
990282003874	putative active site [active]
990282003875	Zn binding site [ion binding]; other site
990282003876	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
990282003877	dimer interface [polypeptide binding]; other site
990282003878	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
990282003879	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
990282003880	GIY-YIG motif/motif A; other site
990282003881	active site
990282003882	catalytic site [active]
990282003883	putative DNA binding site [nucleotide binding]; other site
990282003884	metal binding site [ion binding]; metal-binding site
990282003885	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
990282003886	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
990282003887	homodimer interface [polypeptide binding]; other site
990282003888	NAD binding pocket [chemical binding]; other site
990282003889	ATP binding pocket [chemical binding]; other site
990282003890	Mg binding site [ion binding]; other site
990282003891	active-site loop [active]
990282003892	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
990282003893	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
990282003894	active site
990282003895	P-loop; other site
990282003896	phosphorylation site [posttranslational modification]
990282003897	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
990282003898	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
990282003899	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
990282003900	methionine cluster; other site
990282003901	active site
990282003902	phosphorylation site [posttranslational modification]
990282003903	metal binding site [ion binding]; metal-binding site
990282003904	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
990282003905	Cupin domain; Region: Cupin_2; pfam07883
990282003906	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282003907	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
990282003908	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
990282003909	NAD binding site [chemical binding]; other site
990282003910	sugar binding site [chemical binding]; other site
990282003911	divalent metal binding site [ion binding]; other site
990282003912	tetramer (dimer of dimers) interface [polypeptide binding]; other site
990282003913	dimer interface [polypeptide binding]; other site
990282003914	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
990282003915	putative active site [active]
990282003916	YdjC motif; other site
990282003917	Mg binding site [ion binding]; other site
990282003918	putative homodimer interface [polypeptide binding]; other site
990282003919	hydroperoxidase II; Provisional; Region: katE; PRK11249
990282003920	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
990282003921	tetramer interface [polypeptide binding]; other site
990282003922	heme binding pocket [chemical binding]; other site
990282003923	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
990282003924	domain interactions; other site
990282003925	cell division modulator; Provisional; Region: PRK10113
990282003926	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
990282003927	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
990282003928	inner membrane protein; Provisional; Region: PRK11648
990282003929	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
990282003930	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
990282003931	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282003932	motif II; other site
990282003933	YniB-like protein; Region: YniB; pfam14002
990282003934	Phosphotransferase enzyme family; Region: APH; pfam01636
990282003935	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
990282003936	active site
990282003937	ATP binding site [chemical binding]; other site
990282003938	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
990282003939	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
990282003940	6-phosphofructokinase 2; Provisional; Region: PRK10294
990282003941	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
990282003942	putative substrate binding site [chemical binding]; other site
990282003943	putative ATP binding site [chemical binding]; other site
990282003944	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
990282003945	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
990282003946	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
990282003947	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
990282003948	active site
990282003949	substrate binding site [chemical binding]; other site
990282003950	Mg2+ binding site [ion binding]; other site
990282003951	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
990282003952	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
990282003953	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
990282003954	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
990282003955	active site
990282003956	dimer interface [polypeptide binding]; other site
990282003957	motif 1; other site
990282003958	motif 2; other site
990282003959	motif 3; other site
990282003960	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
990282003961	anticodon binding site; other site
990282003962	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
990282003963	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
990282003964	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
990282003965	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
990282003966	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
990282003967	23S rRNA binding site [nucleotide binding]; other site
990282003968	L21 binding site [polypeptide binding]; other site
990282003969	L13 binding site [polypeptide binding]; other site
990282003970	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
990282003971	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
990282003972	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
990282003973	dimer interface [polypeptide binding]; other site
990282003974	motif 1; other site
990282003975	active site
990282003976	motif 2; other site
990282003977	motif 3; other site
990282003978	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
990282003979	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
990282003980	putative tRNA-binding site [nucleotide binding]; other site
990282003981	B3/4 domain; Region: B3_4; pfam03483
990282003982	tRNA synthetase B5 domain; Region: B5; smart00874
990282003983	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
990282003984	dimer interface [polypeptide binding]; other site
990282003985	motif 1; other site
990282003986	motif 3; other site
990282003987	motif 2; other site
990282003988	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
990282003989	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
990282003990	IHF dimer interface [polypeptide binding]; other site
990282003991	IHF - DNA interface [nucleotide binding]; other site
990282003992	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
990282003993	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
990282003994	ABC-ATPase subunit  interface; other site
990282003995	dimer interface [polypeptide binding]; other site
990282003996	putative PBP binding regions; other site
990282003997	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
990282003998	catalytic residues [active]
990282003999	dimer interface [polypeptide binding]; other site
990282004000	ABC-type cobalamin transport system, ATPase component [Coenzyme metabolism]; Region: BtuD; COG4138
990282004001	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
990282004002	Walker A/P-loop; other site
990282004003	ATP binding site [chemical binding]; other site
990282004004	Q-loop/lid; other site
990282004005	ABC transporter signature motif; other site
990282004006	Walker B; other site
990282004007	D-loop; other site
990282004008	H-loop/switch region; other site
990282004009	NlpC/P60 family; Region: NLPC_P60; pfam00877
990282004010	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
990282004011	Uncharacterized conserved protein [Function unknown]; Region: COG0397
990282004012	hypothetical protein; Validated; Region: PRK00029
990282004013	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
990282004014	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
990282004015	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
990282004016	PEP synthetase regulatory protein; Provisional; Region: PRK05339
990282004017	phosphoenolpyruvate synthase; Validated; Region: PRK06464
990282004018	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
990282004019	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
990282004020	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
990282004021	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
990282004022	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
990282004023	acyl-activating enzyme (AAE) consensus motif; other site
990282004024	putative AMP binding site [chemical binding]; other site
990282004025	putative active site [active]
990282004026	putative CoA binding site [chemical binding]; other site
990282004027	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
990282004028	oxidoreductase; Provisional; Region: PRK10015
990282004029	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
990282004030	Electron transfer flavoprotein domain; Region: ETF; smart00893
990282004031	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
990282004032	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
990282004033	Ligand binding site [chemical binding]; other site
990282004034	Electron transfer flavoprotein domain; Region: ETF; pfam01012
990282004035	Cupin domain; Region: Cupin_2; pfam07883
990282004036	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
990282004037	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282004038	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
990282004039	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
990282004040	active site
990282004041	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
990282004042	Coenzyme A transferase; Region: CoA_trans; smart00882
990282004043	Coenzyme A transferase; Region: CoA_trans; cl17247
990282004044	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
990282004045	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
990282004046	active site
990282004047	catalytic residue [active]
990282004048	dimer interface [polypeptide binding]; other site
990282004049	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
990282004050	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
990282004051	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
990282004052	shikimate binding site; other site
990282004053	NAD(P) binding site [chemical binding]; other site
990282004054	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282004055	putative transporter; Provisional; Region: PRK03699
990282004056	putative substrate translocation pore; other site
990282004057	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282004058	Major Facilitator Superfamily; Region: MFS_1; pfam07690
990282004059	putative substrate translocation pore; other site
990282004060	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
990282004061	putative inner membrane protein; Provisional; Region: PRK10983
990282004062	Domain of unknown function DUF20; Region: UPF0118; pfam01594
990282004063	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
990282004064	FAD binding domain; Region: FAD_binding_4; pfam01565
990282004065	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
990282004066	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
990282004067	CoenzymeA binding site [chemical binding]; other site
990282004068	subunit interaction site [polypeptide binding]; other site
990282004069	PHB binding site; other site
990282004070	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
990282004071	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
990282004072	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
990282004073	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
990282004074	putative ABC transporter; Region: ycf24; CHL00085
990282004075	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
990282004076	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
990282004077	Walker A/P-loop; other site
990282004078	ATP binding site [chemical binding]; other site
990282004079	Q-loop/lid; other site
990282004080	ABC transporter signature motif; other site
990282004081	Walker B; other site
990282004082	D-loop; other site
990282004083	H-loop/switch region; other site
990282004084	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
990282004085	FeS assembly protein SufD; Region: sufD; TIGR01981
990282004086	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
990282004087	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
990282004088	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
990282004089	catalytic residue [active]
990282004090	cysteine desufuration protein SufE; Provisional; Region: PRK09296
990282004091	L,D-transpeptidase; Provisional; Region: PRK10190
990282004092	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
990282004093	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
990282004094	murein lipoprotein; Provisional; Region: PRK15396
990282004095	murein lipoprotein; Provisional; Region: PRK15396
990282004096	pyruvate kinase; Provisional; Region: PRK09206
990282004097	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
990282004098	domain interfaces; other site
990282004099	active site
990282004100	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
990282004101	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
990282004102	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
990282004103	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
990282004104	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
990282004105	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
990282004106	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
990282004107	substrate binding site [chemical binding]; other site
990282004108	dimer interface [polypeptide binding]; other site
990282004109	ATP binding site [chemical binding]; other site
990282004110	tetrathionate reductase subunit A; Provisional; Region: PRK14991
990282004111	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
990282004112	putative [Fe4-S4] binding site [ion binding]; other site
990282004113	putative molybdopterin cofactor binding site [chemical binding]; other site
990282004114	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
990282004115	putative molybdopterin cofactor binding site; other site
990282004116	tetrathionate reductase subunit C; Provisional; Region: PRK14992
990282004117	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
990282004118	tetrathionate reductase subunit B; Provisional; Region: PRK14993
990282004119	4Fe-4S binding domain; Region: Fer4; pfam00037
990282004120	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
990282004121	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
990282004122	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
990282004123	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282004124	dimer interface [polypeptide binding]; other site
990282004125	phosphorylation site [posttranslational modification]
990282004126	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282004127	ATP binding site [chemical binding]; other site
990282004128	Mg2+ binding site [ion binding]; other site
990282004129	G-X-G motif; other site
990282004130	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
990282004131	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282004132	active site
990282004133	phosphorylation site [posttranslational modification]
990282004134	intermolecular recognition site; other site
990282004135	dimerization interface [polypeptide binding]; other site
990282004136	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282004137	DNA binding residues [nucleotide binding]
990282004138	dimerization interface [polypeptide binding]; other site
990282004139	hypothetical protein; Provisional; Region: PRK10292
990282004140	Uncharacterized conserved protein [Function unknown]; Region: COG1683
990282004141	Uncharacterized conserved protein [Function unknown]; Region: COG3272
990282004142	Protein of unknown function (DUF1722); Region: DUF1722; cl01284
990282004143	transcriptional regulator MirA; Provisional; Region: PRK15043
990282004144	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
990282004145	DNA binding residues [nucleotide binding]
990282004146	two component system sensor kinase SsrB; Provisional; Region: PRK15369
990282004147	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282004148	active site
990282004149	phosphorylation site [posttranslational modification]
990282004150	intermolecular recognition site; other site
990282004151	dimerization interface [polypeptide binding]; other site
990282004152	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282004153	DNA binding residues [nucleotide binding]
990282004154	dimerization interface [polypeptide binding]; other site
990282004155	two component system sensor kinase SsrA; Provisional; Region: PRK15347
990282004156	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
990282004157	dimerization interface [polypeptide binding]; other site
990282004158	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282004159	dimer interface [polypeptide binding]; other site
990282004160	phosphorylation site [posttranslational modification]
990282004161	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282004162	ATP binding site [chemical binding]; other site
990282004163	Mg2+ binding site [ion binding]; other site
990282004164	G-X-G motif; other site
990282004165	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282004166	active site
990282004167	phosphorylation site [posttranslational modification]
990282004168	intermolecular recognition site; other site
990282004169	dimerization interface [polypeptide binding]; other site
990282004170	pathogenicity island chaperone protein SpiC; Provisional; Region: PRK15368
990282004171	outer membrane secretin SsaC; Provisional; Region: PRK15346
990282004172	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
990282004173	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
990282004174	type III secretion system protein SsaD; Provisional; Region: PRK15367
990282004175	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
990282004176	type III secretion system chaperone SsaE; Provisional; Region: PRK15366
990282004177	type III secretion system chaperone SseA; Provisional; Region: PRK15365
990282004178	pathogenicity island 2 effector protein SseB; Provisional; Region: PRK15364
990282004179	pathogenicity island 2 chaperone protein SscA; Provisional; Region: PRK15363
990282004180	pathogenicity island 2 effector protein SseC; Provisional; Region: PRK15362
990282004181	pathogenicity island 2 effector protein SseD; Provisional; Region: PRK15361
990282004182	pathogenicity island 2 effector protein SseE; Provisional; Region: PRK15360
990282004183	type III secretion system chaperone protein SscB; Provisional; Region: PRK15359
990282004184	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
990282004185	TPR motif; other site
990282004186	binding surface
990282004187	pathogenicity island 2 effector protein SseF; Provisional; Region: PRK15358
990282004188	pathogenicity island 2 effector protein SseG; Provisional; Region: PRK15357
990282004189	type III secretion system needle protein SsaG; Provisional; Region: PRK15344
990282004190	type III secretion system protein SsaH; Provisional; Region: PRK15356
990282004191	type III secretion system protein SsaI; Provisional; Region: PRK15355
990282004192	type III secretion system lipoprotein SsaJ; Provisional; Region: PRK15348
990282004193	Type III secretion system subunit; Region: T3SS_LEE_assoc; pfam13327
990282004194	type III secretion system protein SsaK; Provisional; Region: PRK15354
990282004195	type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499
990282004196	type III secretion system protein SsaL; Provisional; Region: PRK15345
990282004197	HrpJ-like domain; Region: HrpJ; pfam07201
990282004198	TyeA; Region: TyeA; cl07611
990282004199	type III secretion system protein SsaM; Provisional; Region: PRK15353
990282004200	secretion system apparatus protein SsaV; Provisional; Region: PRK12720
990282004201	FHIPEP family; Region: FHIPEP; pfam00771
990282004202	type III secretion system ATPase SsaN; Validated; Region: PRK07594
990282004203	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
990282004204	Walker A motif; other site
990282004205	ATP binding site [chemical binding]; other site
990282004206	Walker B motif; other site
990282004207	type III secretion system protein SsaO; Provisional; Region: PRK15352
990282004208	type III secretion system protein SsaP; Provisional; Region: PRK15351
990282004209	type III secretion system protein SsaQ; Validated; Region: PRK08035
990282004210	Uncharacterized protein conserved in bacteria (DUF2057); Region: DUF2057; cl11437
990282004211	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
990282004212	Type III secretory pathway, component EscR [Intracellular trafficking and secretion]; Region: EscR; COG4790
990282004213	type III secretion system protein SsaS; Provisional; Region: PRK15350
990282004214	type III secretion system protein SsaT; Provisional; Region: PRK15349
990282004215	secretion system apparatus protein SsaU; Reviewed; Region: PRK12721
990282004216	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
990282004217	multidrug efflux protein; Reviewed; Region: PRK01766
990282004218	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
990282004219	cation binding site [ion binding]; other site
990282004220	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
990282004221	Lumazine binding domain; Region: Lum_binding; pfam00677
990282004222	Lumazine binding domain; Region: Lum_binding; pfam00677
990282004223	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
990282004224	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282004225	S-adenosylmethionine binding site [chemical binding]; other site
990282004226	putative transporter; Provisional; Region: PRK11043
990282004227	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282004228	putative substrate translocation pore; other site
990282004229	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
990282004230	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282004231	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
990282004232	dimerization interface [polypeptide binding]; other site
990282004233	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
990282004234	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
990282004235	DNA binding site [nucleotide binding]
990282004236	domain linker motif; other site
990282004237	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
990282004238	dimerization interface [polypeptide binding]; other site
990282004239	ligand binding site [chemical binding]; other site
990282004240	superoxide dismutase; Provisional; Region: PRK10543
990282004241	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
990282004242	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
990282004243	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
990282004244	NlpC/P60 family; Region: NLPC_P60; pfam00877
990282004245	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
990282004246	putative GSH binding site [chemical binding]; other site
990282004247	catalytic residues [active]
990282004248	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
990282004249	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
990282004250	dimer interface [polypeptide binding]; other site
990282004251	catalytic site [active]
990282004252	putative active site [active]
990282004253	putative substrate binding site [chemical binding]; other site
990282004254	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
990282004255	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
990282004256	dimer interface [polypeptide binding]; other site
990282004257	active site
990282004258	metal binding site [ion binding]; metal-binding site
990282004259	glutathione binding site [chemical binding]; other site
990282004260	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
990282004261	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
990282004262	FMN binding site [chemical binding]; other site
990282004263	active site
990282004264	substrate binding site [chemical binding]; other site
990282004265	catalytic residue [active]
990282004266	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
990282004267	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
990282004268	Predicted Fe-S protein [General function prediction only]; Region: COG3313
990282004269	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
990282004270	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
990282004271	active site
990282004272	catalytic tetrad [active]
990282004273	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
990282004274	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
990282004275	E-class dimer interface [polypeptide binding]; other site
990282004276	P-class dimer interface [polypeptide binding]; other site
990282004277	active site
990282004278	Cu2+ binding site [ion binding]; other site
990282004279	Zn2+ binding site [ion binding]; other site
990282004280	Fusaric acid resistance protein family; Region: FUSC; pfam04632
990282004281	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
990282004282	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
990282004283	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
990282004284	HlyD family secretion protein; Region: HlyD_3; pfam13437
990282004285	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
990282004286	transcriptional regulator SlyA; Provisional; Region: PRK03573
990282004287	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
990282004288	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
990282004289	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
990282004290	lysozyme inhibitor; Provisional; Region: PRK11372
990282004291	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
990282004292	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
990282004293	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
990282004294	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
990282004295	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
990282004296	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
990282004297	active site
990282004298	HIGH motif; other site
990282004299	dimer interface [polypeptide binding]; other site
990282004300	KMSKS motif; other site
990282004301	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
990282004302	RNA binding surface [nucleotide binding]; other site
990282004303	pyridoxamine kinase; Validated; Region: PRK05756
990282004304	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
990282004305	dimer interface [polypeptide binding]; other site
990282004306	pyridoxal binding site [chemical binding]; other site
990282004307	ATP binding site [chemical binding]; other site
990282004308	glutathionine S-transferase; Provisional; Region: PRK10542
990282004309	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
990282004310	C-terminal domain interface [polypeptide binding]; other site
990282004311	GSH binding site (G-site) [chemical binding]; other site
990282004312	dimer interface [polypeptide binding]; other site
990282004313	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
990282004314	dimer interface [polypeptide binding]; other site
990282004315	N-terminal domain interface [polypeptide binding]; other site
990282004316	substrate binding pocket (H-site) [chemical binding]; other site
990282004317	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
990282004318	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282004319	putative substrate translocation pore; other site
990282004320	POT family; Region: PTR2; pfam00854
990282004321	endonuclease III; Provisional; Region: PRK10702
990282004322	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
990282004323	minor groove reading motif; other site
990282004324	helix-hairpin-helix signature motif; other site
990282004325	substrate binding pocket [chemical binding]; other site
990282004326	active site
990282004327	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
990282004328	electron transport complex RsxE subunit; Provisional; Region: PRK12405
990282004329	electron transport complex protein RnfG; Validated; Region: PRK01908
990282004330	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
990282004331	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
990282004332	SLBB domain; Region: SLBB; pfam10531
990282004333	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
990282004334	electron transport complex protein RnfB; Provisional; Region: PRK05113
990282004335	Putative Fe-S cluster; Region: FeS; cl17515
990282004336	4Fe-4S binding domain; Region: Fer4; pfam00037
990282004337	electron transport complex protein RsxA; Provisional; Region: PRK05151
990282004338	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
990282004339	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
990282004340	putative oxidoreductase; Provisional; Region: PRK11579
990282004341	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
990282004342	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
990282004343	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
990282004344	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
990282004345	active site
990282004346	purine riboside binding site [chemical binding]; other site
990282004347	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
990282004348	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
990282004349	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
990282004350	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
990282004351	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
990282004352	fumarate hydratase; Provisional; Region: PRK15389
990282004353	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
990282004354	Fumarase C-terminus; Region: Fumerase_C; pfam05683
990282004355	fumarate hydratase; Reviewed; Region: fumC; PRK00485
990282004356	Class II fumarases; Region: Fumarase_classII; cd01362
990282004357	active site
990282004358	tetramer interface [polypeptide binding]; other site
990282004359	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
990282004360	sensor protein RstB; Provisional; Region: PRK10604
990282004361	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
990282004362	dimerization interface [polypeptide binding]; other site
990282004363	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282004364	dimer interface [polypeptide binding]; other site
990282004365	phosphorylation site [posttranslational modification]
990282004366	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282004367	ATP binding site [chemical binding]; other site
990282004368	Mg2+ binding site [ion binding]; other site
990282004369	G-X-G motif; other site
990282004370	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
990282004371	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
990282004372	active site
990282004373	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
990282004374	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
990282004375	trimer interface [polypeptide binding]; other site
990282004376	eyelet of channel; other site
990282004377	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
990282004378	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282004379	active site
990282004380	phosphorylation site [posttranslational modification]
990282004381	intermolecular recognition site; other site
990282004382	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
990282004383	DNA binding site [nucleotide binding]
990282004384	GlpM protein; Region: GlpM; pfam06942
990282004385	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
990282004386	Spore germination protein; Region: Spore_permease; cl17796
990282004387	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
990282004388	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
990282004389	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
990282004390	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
990282004391	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
990282004392	ligand binding site [chemical binding]; other site
990282004393	homodimer interface [polypeptide binding]; other site
990282004394	NAD(P) binding site [chemical binding]; other site
990282004395	trimer interface B [polypeptide binding]; other site
990282004396	trimer interface A [polypeptide binding]; other site
990282004397	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
990282004398	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
990282004399	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
990282004400	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
990282004401	Domain of unknown function DUF20; Region: UPF0118; pfam01594
990282004402	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
990282004403	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
990282004404	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
990282004405	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
990282004406	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282004407	putative substrate translocation pore; other site
990282004408	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
990282004409	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282004410	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
990282004411	dimerization interface [polypeptide binding]; other site
990282004412	substrate binding pocket [chemical binding]; other site
990282004413	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
990282004414	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
990282004415	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
990282004416	putative dithiobiotin synthetase; Provisional; Region: PRK12374
990282004417	AAA domain; Region: AAA_26; pfam13500
990282004418	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
990282004419	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
990282004420	Cl- selectivity filter; other site
990282004421	Cl- binding residues [ion binding]; other site
990282004422	pore gating glutamate residue; other site
990282004423	dimer interface [polypeptide binding]; other site
990282004424	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
990282004425	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
990282004426	Walker A/P-loop; other site
990282004427	ATP binding site [chemical binding]; other site
990282004428	Q-loop/lid; other site
990282004429	ABC transporter signature motif; other site
990282004430	Walker B; other site
990282004431	D-loop; other site
990282004432	H-loop/switch region; other site
990282004433	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc; cd04582
990282004434	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282004435	dimer interface [polypeptide binding]; other site
990282004436	conserved gate region; other site
990282004437	ABC-ATPase subunit interface; other site
990282004438	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
990282004439	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282004440	dimer interface [polypeptide binding]; other site
990282004441	conserved gate region; other site
990282004442	putative PBP binding loops; other site
990282004443	ABC-ATPase subunit interface; other site
990282004444	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
990282004445	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
990282004446	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
990282004447	4Fe-4S binding domain; Region: Fer4; pfam00037
990282004448	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
990282004449	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
990282004450	putative [Fe4-S4] binding site [ion binding]; other site
990282004451	putative molybdopterin cofactor binding site [chemical binding]; other site
990282004452	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
990282004453	putative molybdopterin cofactor binding site; other site
990282004454	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
990282004455	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
990282004456	putative [Fe4-S4] binding site [ion binding]; other site
990282004457	putative molybdopterin cofactor binding site [chemical binding]; other site
990282004458	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
990282004459	putative molybdopterin cofactor binding site; other site
990282004460	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
990282004461	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
990282004462	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
990282004463	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282004464	Coenzyme A binding pocket [chemical binding]; other site
990282004465	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
990282004466	hypothetical protein; Provisional; Region: PRK13659
990282004467	hypothetical protein; Provisional; Region: PRK02237
990282004468	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
990282004469	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
990282004470	putative active site pocket [active]
990282004471	putative metal binding site [ion binding]; other site
990282004472	putative oxidoreductase; Provisional; Region: PRK10083
990282004473	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
990282004474	putative NAD(P) binding site [chemical binding]; other site
990282004475	catalytic Zn binding site [ion binding]; other site
990282004476	structural Zn binding site [ion binding]; other site
990282004477	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282004478	putative substrate translocation pore; other site
990282004479	metabolite-proton symporter; Region: 2A0106; TIGR00883
990282004480	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
990282004481	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
990282004482	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
990282004483	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
990282004484	Transcriptional regulators [Transcription]; Region: GntR; COG1802
990282004485	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282004486	DNA-binding site [nucleotide binding]; DNA binding site
990282004487	FCD domain; Region: FCD; pfam07729
990282004488	malonic semialdehyde reductase; Provisional; Region: PRK10538
990282004489	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
990282004490	putative NAD(P) binding site [chemical binding]; other site
990282004491	homodimer interface [polypeptide binding]; other site
990282004492	homotetramer interface [polypeptide binding]; other site
990282004493	active site
990282004494	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
990282004495	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
990282004496	active site
990282004497	Zn binding site [ion binding]; other site
990282004498	General stress protein [General function prediction only]; Region: GsiB; COG3729
990282004499	hypothetical protein; Validated; Region: PRK03657
990282004500	hypothetical protein; Provisional; Region: PRK10053
990282004501	putative transporter; Provisional; Region: PRK10054
990282004502	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282004503	putative substrate translocation pore; other site
990282004504	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
990282004505	EamA-like transporter family; Region: EamA; pfam00892
990282004506	MarB protein; Region: MarB; pfam13999
990282004507	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
990282004508	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282004509	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
990282004510	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
990282004511	inner membrane protein; Provisional; Region: PRK10995
990282004512	putative arabinose transporter; Provisional; Region: PRK03545
990282004513	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282004514	putative substrate translocation pore; other site
990282004515	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282004516	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282004517	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
990282004518	putative dimerization interface [polypeptide binding]; other site
990282004519	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
990282004520	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
990282004521	NAD(P) binding site [chemical binding]; other site
990282004522	catalytic residues [active]
990282004523	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
990282004524	glutaminase; Provisional; Region: PRK00971
990282004525	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
990282004526	Predicted membrane protein [Function unknown]; Region: COG3781
990282004527	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
990282004528	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
990282004529	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
990282004530	trimer interface [polypeptide binding]; other site
990282004531	eyelet of channel; other site
990282004532	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
990282004533	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
990282004534	Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion]; Region: FrhA; COG3259
990282004535	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
990282004536	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
990282004537	Rubredoxin [Energy production and conversion]; Region: COG1773
990282004538	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
990282004539	iron binding site [ion binding]; other site
990282004540	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
990282004541	HupF/HypC family; Region: HupF_HypC; cl00394
990282004542	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
990282004543	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
990282004544	putative substrate-binding site; other site
990282004545	nickel binding site [ion binding]; other site
990282004546	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
990282004547	hydrogenase 1 large subunit; Provisional; Region: PRK10170
990282004548	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
990282004549	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
990282004550	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
990282004551	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
990282004552	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
990282004553	active site
990282004554	Transcriptional regulators [Transcription]; Region: FadR; COG2186
990282004555	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282004556	DNA-binding site [nucleotide binding]; DNA binding site
990282004557	FCD domain; Region: FCD; pfam07729
990282004558	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
990282004559	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
990282004560	putative NAD(P) binding site [chemical binding]; other site
990282004561	catalytic Zn binding site [ion binding]; other site
990282004562	structural Zn binding site [ion binding]; other site
990282004563	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282004564	D-galactonate transporter; Region: 2A0114; TIGR00893
990282004565	putative substrate translocation pore; other site
990282004566	PhoPQ-activated pathogenicity-related protein [General function prediction only]; Region: PqaA; COG4287
990282004567	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282004568	Major Facilitator Superfamily; Region: MFS_1; pfam07690
990282004569	putative substrate translocation pore; other site
990282004570	hypothetical protein; Provisional; Region: PRK06184
990282004571	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
990282004572	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
990282004573	Transcriptional regulators [Transcription]; Region: MarR; COG1846
990282004574	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
990282004575	putative DNA binding site [nucleotide binding]; other site
990282004576	putative Zn2+ binding site [ion binding]; other site
990282004577	S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) [Translation, ribosomal structure and biogenesis]; Region: QueA; COG0809
990282004578	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
990282004579	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
990282004580	homotrimer interaction site [polypeptide binding]; other site
990282004581	putative active site [active]
990282004582	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
990282004583	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: StbD; COG2161
990282004584	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
990282004585	Transcriptional regulators [Transcription]; Region: PurR; COG1609
990282004586	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
990282004587	DNA binding site [nucleotide binding]
990282004588	domain linker motif; other site
990282004589	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
990282004590	dimerization interface (closed form) [polypeptide binding]; other site
990282004591	ligand binding site [chemical binding]; other site
990282004592	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
990282004593	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
990282004594	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
990282004595	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282004596	homodimer interface [polypeptide binding]; other site
990282004597	catalytic residue [active]
990282004598	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
990282004599	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
990282004600	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
990282004601	active site
990282004602	catalytic site [active]
990282004603	Maltooligosyl trehalose synthase [Carbohydrate transport and metabolism]; Region: TreY; COG3280
990282004604	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
990282004605	active site
990282004606	catalytic site [active]
990282004607	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
990282004608	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
990282004609	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
990282004610	catalytic site [active]
990282004611	active site
990282004612	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
990282004613	Protein of unknown function (DUF1264); Region: DUF1264; pfam06884
990282004614	acid-resistance protein; Provisional; Region: hdeB; PRK11566
990282004615	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
990282004616	biofilm-dependent modulation protein; Provisional; Region: PRK11436
990282004617	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
990282004618	malate dehydrogenase; Provisional; Region: PRK13529
990282004619	Malic enzyme, N-terminal domain; Region: malic; pfam00390
990282004620	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
990282004621	NAD(P) binding site [chemical binding]; other site
990282004622	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
990282004623	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
990282004624	NAD binding site [chemical binding]; other site
990282004625	substrate binding site [chemical binding]; other site
990282004626	catalytic Zn binding site [ion binding]; other site
990282004627	tetramer interface [polypeptide binding]; other site
990282004628	structural Zn binding site [ion binding]; other site
990282004629	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
990282004630	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
990282004631	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
990282004632	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
990282004633	aromatic amino acid exporter; Provisional; Region: PRK11689
990282004634	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
990282004635	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
990282004636	trimer interface [polypeptide binding]; other site
990282004637	eyelet of channel; other site
990282004638	Uncharacterized conserved protein [Function unknown]; Region: COG3791
990282004639	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
990282004640	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282004641	putative substrate translocation pore; other site
990282004642	TetR family transcriptional regulator; Provisional; Region: PRK14996
990282004643	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
990282004644	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
990282004645	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
990282004646	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
990282004647	[4Fe-4S] binding site [ion binding]; other site
990282004648	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
990282004649	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
990282004650	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
990282004651	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
990282004652	molybdopterin cofactor binding site; other site
990282004653	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
990282004654	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
990282004655	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
990282004656	hypothetical protein; Provisional; Region: PRK10281
990282004657	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
990282004658	L-asparagine permease; Provisional; Region: PRK15049
990282004659	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
990282004660	Uncharacterized conserved protein [Function unknown]; Region: COG3391
990282004661	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
990282004662	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
990282004663	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
990282004664	N-terminal plug; other site
990282004665	ligand-binding site [chemical binding]; other site
990282004666	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
990282004667	DNA-binding site [nucleotide binding]; DNA binding site
990282004668	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
990282004669	FCD domain; Region: FCD; pfam07729
990282004670	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
990282004671	Prostaglandin dehydrogenases; Region: PGDH; cd05288
990282004672	NAD(P) binding site [chemical binding]; other site
990282004673	substrate binding site [chemical binding]; other site
990282004674	dimer interface [polypeptide binding]; other site
990282004675	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
990282004676	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
990282004677	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
990282004678	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
990282004679	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfB; COG4457
990282004680	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfC; COG4458
990282004681	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
990282004682	1-pyrroline dehydrogenase; Region: ABALDH; TIGR03374
990282004683	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
990282004684	tetrameric interface [polypeptide binding]; other site
990282004685	NAD binding site [chemical binding]; other site
990282004686	catalytic residues [active]
990282004687	substrate binding site [chemical binding]; other site
990282004688	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
990282004689	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282004690	DNA-binding site [nucleotide binding]; DNA binding site
990282004691	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
990282004692	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282004693	homodimer interface [polypeptide binding]; other site
990282004694	catalytic residue [active]
990282004695	D-alanyl-D-alanine dipeptidase [Cell envelope biogenesis, outer membrane]; Region: DdpX; COG2173
990282004696	secreted effector protein SifB; Provisional; Region: sifB; PRK09499
990282004697	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
990282004698	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
990282004699	Peptidase family U32; Region: Peptidase_U32; pfam01136
990282004700	Collagenase; Region: DUF3656; pfam12392
990282004701	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
990282004702	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
990282004703	non-specific DNA binding site [nucleotide binding]; other site
990282004704	salt bridge; other site
990282004705	sequence-specific DNA binding site [nucleotide binding]; other site
990282004706	Cupin domain; Region: Cupin_2; pfam07883
990282004707	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
990282004708	benzoate transporter; Region: benE; TIGR00843
990282004709	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
990282004710	tellurite resistance protein TehB; Provisional; Region: PRK11207
990282004711	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282004712	S-adenosylmethionine binding site [chemical binding]; other site
990282004713	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
990282004714	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
990282004715	gating phenylalanine in ion channel; other site
990282004716	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
990282004717	putative trimer interface [polypeptide binding]; other site
990282004718	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
990282004719	putative trimer interface [polypeptide binding]; other site
990282004720	putative CoA binding site [chemical binding]; other site
990282004721	putative CoA binding site [chemical binding]; other site
990282004722	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
990282004723	putative trimer interface [polypeptide binding]; other site
990282004724	putative CoA binding site [chemical binding]; other site
990282004725	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
990282004726	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282004727	Coenzyme A binding pocket [chemical binding]; other site
990282004728	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
990282004729	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
990282004730	oligomer interface [polypeptide binding]; other site
990282004731	active site
990282004732	metal binding site [ion binding]; metal-binding site
990282004733	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
990282004734	active site
990282004735	P-loop; other site
990282004736	phosphorylation site [posttranslational modification]
990282004737	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
990282004738	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
990282004739	membrane complex biogenesis protein, BtpA family; Region: thylakoid_BtpA; TIGR00259
990282004740	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
990282004741	active site
990282004742	phosphorylation site [posttranslational modification]
990282004743	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
990282004744	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
990282004745	substrate binding site [chemical binding]; other site
990282004746	hexamer interface [polypeptide binding]; other site
990282004747	metal binding site [ion binding]; metal-binding site
990282004748	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
990282004749	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
990282004750	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
990282004751	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
990282004752	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282004753	Coenzyme A binding pocket [chemical binding]; other site
990282004754	L-lactate oxidase; Region: L_lactate_ox; TIGR02708
990282004755	L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2.  This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737
990282004756	teramer interface [polypeptide binding]; other site
990282004757	active site
990282004758	FMN binding site [chemical binding]; other site
990282004759	catalytic residues [active]
990282004760	Uncharacterized conserved protein [Function unknown]; Region: COG2353
990282004761	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
990282004762	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
990282004763	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
990282004764	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
990282004765	substrate binding pocket [chemical binding]; other site
990282004766	catalytic triad [active]
990282004767	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
990282004768	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
990282004769	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
990282004770	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282004771	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
990282004772	dimerization interface [polypeptide binding]; other site
990282004773	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
990282004774	dimer interface [polypeptide binding]; other site
990282004775	ligand binding site [chemical binding]; other site
990282004776	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
990282004777	HAMP domain; Region: HAMP; pfam00672
990282004778	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
990282004779	dimer interface [polypeptide binding]; other site
990282004780	putative CheW interface [polypeptide binding]; other site
990282004781	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
990282004782	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
990282004783	substrate binding site [chemical binding]; other site
990282004784	catalytic Zn binding site [ion binding]; other site
990282004785	NAD binding site [chemical binding]; other site
990282004786	structural Zn binding site [ion binding]; other site
990282004787	dimer interface [polypeptide binding]; other site
990282004788	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
990282004789	putative metal binding site [ion binding]; other site
990282004790	putative homodimer interface [polypeptide binding]; other site
990282004791	putative homotetramer interface [polypeptide binding]; other site
990282004792	putative homodimer-homodimer interface [polypeptide binding]; other site
990282004793	putative allosteric switch controlling residues; other site
990282004794	Sif protein; Region: Sif; cl11505
990282004795	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
990282004796	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
990282004797	active site
990282004798	catalytic triad [active]
990282004799	oxyanion hole [active]
990282004800	Predicted membrane protein [Function unknown]; Region: COG3326
990282004801	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
990282004802	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
990282004803	substrate binding pocket [chemical binding]; other site
990282004804	membrane-bound complex binding site; other site
990282004805	hinge residues; other site
990282004806	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
990282004807	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282004808	dimer interface [polypeptide binding]; other site
990282004809	conserved gate region; other site
990282004810	putative PBP binding loops; other site
990282004811	ABC-ATPase subunit interface; other site
990282004812	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
990282004813	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282004814	Walker A/P-loop; other site
990282004815	ATP binding site [chemical binding]; other site
990282004816	Q-loop/lid; other site
990282004817	ABC transporter signature motif; other site
990282004818	Walker B; other site
990282004819	D-loop; other site
990282004820	H-loop/switch region; other site
990282004821	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
990282004822	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282004823	dimer interface [polypeptide binding]; other site
990282004824	conserved gate region; other site
990282004825	putative PBP binding loops; other site
990282004826	ABC-ATPase subunit interface; other site
990282004827	Predicted membrane protein [Function unknown]; Region: COG5305
990282004828	Methyltransferase domain; Region: Methyltransf_12; pfam08242
990282004829	cytochrome b561; Provisional; Region: PRK11513
990282004830	Uncharacterized conserved protein [Function unknown]; Region: COG1434
990282004831	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
990282004832	putative active site [active]
990282004833	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
990282004834	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
990282004835	ATP binding site [chemical binding]; other site
990282004836	putative Mg++ binding site [ion binding]; other site
990282004837	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
990282004838	nucleotide binding region [chemical binding]; other site
990282004839	ATP-binding site [chemical binding]; other site
990282004840	Helicase associated domain (HA2); Region: HA2; pfam04408
990282004841	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
990282004842	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
990282004843	azoreductase; Reviewed; Region: PRK00170
990282004844	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
990282004845	Uncharacterized conserved protein [Function unknown]; Region: COG3791
990282004846	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
990282004847	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
990282004848	hypothetical protein; Provisional; Region: PRK10695
990282004849	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
990282004850	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
990282004851	putative ligand binding site [chemical binding]; other site
990282004852	putative NAD binding site [chemical binding]; other site
990282004853	catalytic site [active]
990282004854	heat-inducible protein; Provisional; Region: PRK10449
990282004855	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
990282004856	Domain of unknown function (DUF333); Region: DUF333; pfam03891
990282004857	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
990282004858	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
990282004859	dimer interface [polypeptide binding]; other site
990282004860	PYR/PP interface [polypeptide binding]; other site
990282004861	TPP binding site [chemical binding]; other site
990282004862	substrate binding site [chemical binding]; other site
990282004863	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
990282004864	Domain of unknown function; Region: EKR; smart00890
990282004865	4Fe-4S binding domain; Region: Fer4_6; pfam12837
990282004866	4Fe-4S binding domain; Region: Fer4; pfam00037
990282004867	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
990282004868	TPP-binding site [chemical binding]; other site
990282004869	dimer interface [polypeptide binding]; other site
990282004870	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
990282004871	Ligand Binding Site [chemical binding]; other site
990282004872	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
990282004873	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
990282004874	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
990282004875	Ligand Binding Site [chemical binding]; other site
990282004876	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
990282004877	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
990282004878	ATP binding site [chemical binding]; other site
990282004879	Mg++ binding site [ion binding]; other site
990282004880	motif III; other site
990282004881	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
990282004882	nucleotide binding region [chemical binding]; other site
990282004883	ATP-binding site [chemical binding]; other site
990282004884	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
990282004885	putative RNA binding site [nucleotide binding]; other site
990282004886	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
990282004887	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
990282004888	Cl binding site [ion binding]; other site
990282004889	oligomer interface [polypeptide binding]; other site
990282004890	HAMP domain; Region: HAMP; pfam00672
990282004891	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
990282004892	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
990282004893	dimer interface [polypeptide binding]; other site
990282004894	putative CheW interface [polypeptide binding]; other site
990282004895	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
990282004896	Smr domain; Region: Smr; pfam01713
990282004897	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
990282004898	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
990282004899	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
990282004900	DNA binding site [nucleotide binding]
990282004901	active site
990282004902	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
990282004903	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
990282004904	ligand binding site [chemical binding]; other site
990282004905	flexible hinge region; other site
990282004906	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
990282004907	putative switch regulator; other site
990282004908	non-specific DNA interactions [nucleotide binding]; other site
990282004909	DNA binding site [nucleotide binding]
990282004910	sequence specific DNA binding site [nucleotide binding]; other site
990282004911	putative cAMP binding site [chemical binding]; other site
990282004912	universal stress protein UspE; Provisional; Region: PRK11175
990282004913	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
990282004914	Ligand Binding Site [chemical binding]; other site
990282004915	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
990282004916	Ligand Binding Site [chemical binding]; other site
990282004917	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
990282004918	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
990282004919	Mechanosensitive ion channel; Region: MS_channel; pfam00924
990282004920	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
990282004921	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
990282004922	non-specific DNA binding site [nucleotide binding]; other site
990282004923	salt bridge; other site
990282004924	sequence-specific DNA binding site [nucleotide binding]; other site
990282004925	Cupin domain; Region: Cupin_2; pfam07883
990282004926	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
990282004927	B3/4 domain; Region: B3_4; pfam03483
990282004928	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: Tpx; COG2077
990282004929	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
990282004930	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
990282004931	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
990282004932	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
990282004933	oxidoreductase; Provisional; Region: PRK12742
990282004934	classical (c) SDRs; Region: SDR_c; cd05233
990282004935	NAD(P) binding site [chemical binding]; other site
990282004936	active site
990282004937	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
990282004938	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
990282004939	active site
990282004940	catalytic tetrad [active]
990282004941	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282004942	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282004943	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
990282004944	putative effector binding pocket; other site
990282004945	putative dimerization interface [polypeptide binding]; other site
990282004946	phenylcoumaran benzylic ether reductase (PCBER) like, atypical (a) SDRs; Region: PCBER_SDR_a; cd05259
990282004947	NmrA-like family; Region: NmrA; pfam05368
990282004948	NAD(P) binding site [chemical binding]; other site
990282004949	active site lysine
990282004950	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
990282004951	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
990282004952	peptide binding site [polypeptide binding]; other site
990282004953	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
990282004954	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
990282004955	putative active site [active]
990282004956	Zn binding site [ion binding]; other site
990282004957	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
990282004958	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
990282004959	active site
990282004960	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
990282004961	dimer interface [polypeptide binding]; other site
990282004962	catalytic triad [active]
990282004963	peroxidatic and resolving cysteines [active]
990282004964	Transposase IS200 like; Region: Y1_Tnp; pfam01797
990282004965	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
990282004966	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
990282004967	putative aromatic amino acid binding site; other site
990282004968	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282004969	Walker A motif; other site
990282004970	ATP binding site [chemical binding]; other site
990282004971	Walker B motif; other site
990282004972	arginine finger; other site
990282004973	hypothetical protein; Provisional; Region: PRK05415
990282004974	TIGR01620 family protein; Region: hyp_HI0043
990282004975	Predicted ATPase [General function prediction only]; Region: COG3106
990282004976	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
990282004977	active site residue [active]
990282004978	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
990282004979	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
990282004980	phage shock protein C; Region: phageshock_pspC; TIGR02978
990282004981	phage shock protein B; Provisional; Region: pspB; PRK09458
990282004982	phage shock protein PspA; Provisional; Region: PRK10698
990282004983	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
990282004984	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282004985	Walker A motif; other site
990282004986	ATP binding site [chemical binding]; other site
990282004987	Walker B motif; other site
990282004988	arginine finger; other site
990282004989	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
990282004990	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
990282004991	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
990282004992	peptide binding site [polypeptide binding]; other site
990282004993	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
990282004994	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282004995	dimer interface [polypeptide binding]; other site
990282004996	conserved gate region; other site
990282004997	putative PBP binding loops; other site
990282004998	ABC-ATPase subunit interface; other site
990282004999	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
990282005000	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
990282005001	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282005002	dimer interface [polypeptide binding]; other site
990282005003	conserved gate region; other site
990282005004	putative PBP binding loops; other site
990282005005	ABC-ATPase subunit interface; other site
990282005006	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
990282005007	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
990282005008	Walker A/P-loop; other site
990282005009	ATP binding site [chemical binding]; other site
990282005010	Q-loop/lid; other site
990282005011	ABC transporter signature motif; other site
990282005012	Walker B; other site
990282005013	D-loop; other site
990282005014	H-loop/switch region; other site
990282005015	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
990282005016	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
990282005017	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
990282005018	Walker A/P-loop; other site
990282005019	ATP binding site [chemical binding]; other site
990282005020	Q-loop/lid; other site
990282005021	ABC transporter signature motif; other site
990282005022	Walker B; other site
990282005023	D-loop; other site
990282005024	H-loop/switch region; other site
990282005025	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
990282005026	Protein kinase domain; Region: Pkinase; pfam00069
990282005027	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
990282005028	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
990282005029	NAD binding site [chemical binding]; other site
990282005030	homotetramer interface [polypeptide binding]; other site
990282005031	homodimer interface [polypeptide binding]; other site
990282005032	substrate binding site [chemical binding]; other site
990282005033	active site
990282005034	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
990282005035	Uncharacterized conserved protein [Function unknown]; Region: COG2128
990282005036	exoribonuclease II; Provisional; Region: PRK05054
990282005037	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
990282005038	RNB domain; Region: RNB; pfam00773
990282005039	S1 RNA binding domain; Region: S1; pfam00575
990282005040	RNase II stability modulator; Provisional; Region: PRK10060
990282005041	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
990282005042	putative active site [active]
990282005043	heme pocket [chemical binding]; other site
990282005044	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
990282005045	metal binding site [ion binding]; metal-binding site
990282005046	active site
990282005047	I-site; other site
990282005048	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
990282005049	hypothetical protein; Provisional; Region: PRK13658
990282005050	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
990282005051	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
990282005052	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
990282005053	lipoprotein; Provisional; Region: PRK10540
990282005054	translation initiation factor Sui1; Validated; Region: PRK06824
990282005055	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
990282005056	putative rRNA binding site [nucleotide binding]; other site
990282005057	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
990282005058	active site
990282005059	dimer interface [polypeptide binding]; other site
990282005060	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
990282005061	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
990282005062	binding surface
990282005063	TPR motif; other site
990282005064	Predicted membrane protein [Function unknown]; Region: COG3771
990282005065	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
990282005066	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
990282005067	active site
990282005068	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
990282005069	dimerization interface [polypeptide binding]; other site
990282005070	active site
990282005071	aconitate hydratase; Validated; Region: PRK09277
990282005072	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
990282005073	substrate binding site [chemical binding]; other site
990282005074	ligand binding site [chemical binding]; other site
990282005075	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
990282005076	substrate binding site [chemical binding]; other site
990282005077	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
990282005078	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282005079	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
990282005080	substrate binding site [chemical binding]; other site
990282005081	putative dimerization interface [polypeptide binding]; other site
990282005082	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
990282005083	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
990282005084	active site
990282005085	interdomain interaction site; other site
990282005086	putative metal-binding site [ion binding]; other site
990282005087	nucleotide binding site [chemical binding]; other site
990282005088	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
990282005089	domain I; other site
990282005090	DNA binding groove [nucleotide binding]
990282005091	phosphate binding site [ion binding]; other site
990282005092	domain II; other site
990282005093	domain III; other site
990282005094	nucleotide binding site [chemical binding]; other site
990282005095	catalytic site [active]
990282005096	domain IV; other site
990282005097	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
990282005098	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
990282005099	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
990282005100	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
990282005101	hypothetical protein; Provisional; Region: PRK11037
990282005102	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
990282005103	putative inner membrane peptidase; Provisional; Region: PRK11778
990282005104	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
990282005105	tandem repeat interface [polypeptide binding]; other site
990282005106	oligomer interface [polypeptide binding]; other site
990282005107	active site residues [active]
990282005108	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
990282005109	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
990282005110	NADP binding site [chemical binding]; other site
990282005111	homodimer interface [polypeptide binding]; other site
990282005112	active site
990282005113	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
990282005114	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; cl17276
990282005115	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
990282005116	homodimer interface [polypeptide binding]; other site
990282005117	Walker A motif; other site
990282005118	ATP binding site [chemical binding]; other site
990282005119	hydroxycobalamin binding site [chemical binding]; other site
990282005120	Walker B motif; other site
990282005121	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
990282005122	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
990282005123	RNA binding surface [nucleotide binding]; other site
990282005124	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
990282005125	probable active site [active]
990282005126	hypothetical protein; Provisional; Region: PRK11630
990282005127	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
990282005128	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
990282005129	active site
990282005130	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
990282005131	anthranilate synthase component I; Provisional; Region: PRK13564
990282005132	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
990282005133	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
990282005134	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
990282005135	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
990282005136	glutamine binding [chemical binding]; other site
990282005137	catalytic triad [active]
990282005138	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
990282005139	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
990282005140	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
990282005141	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
990282005142	active site
990282005143	ribulose/triose binding site [chemical binding]; other site
990282005144	phosphate binding site [ion binding]; other site
990282005145	substrate (anthranilate) binding pocket [chemical binding]; other site
990282005146	product (indole) binding pocket [chemical binding]; other site
990282005147	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
990282005148	active site
990282005149	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
990282005150	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
990282005151	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282005152	catalytic residue [active]
990282005153	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
990282005154	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
990282005155	substrate binding site [chemical binding]; other site
990282005156	active site
990282005157	catalytic residues [active]
990282005158	heterodimer interface [polypeptide binding]; other site
990282005159	General stress protein [General function prediction only]; Region: GsiB; COG3729
990282005160	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
990282005161	dimerization interface [polypeptide binding]; other site
990282005162	metal binding site [ion binding]; metal-binding site
990282005163	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
990282005164	dinuclear metal binding motif [ion binding]; other site
990282005165	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
990282005166	dimanganese center [ion binding]; other site
990282005167	outer membrane protein W; Provisional; Region: PRK10959
990282005168	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
990282005169	hypothetical protein; Provisional; Region: PRK02868
990282005170	intracellular septation protein A; Reviewed; Region: PRK00259
990282005171	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
990282005172	transport protein TonB; Provisional; Region: PRK10819
990282005173	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
990282005174	YciI-like protein; Reviewed; Region: PRK11370
990282005175	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
990282005176	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
990282005177	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
990282005178	putative active site [active]
990282005179	catalytic site [active]
990282005180	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
990282005181	putative active site [active]
990282005182	catalytic site [active]
990282005183	dsDNA-mimic protein; Reviewed; Region: PRK05094
990282005184	Ion transport protein; Region: Ion_trans; pfam00520
990282005185	Ion channel; Region: Ion_trans_2; pfam07885
990282005186	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
990282005187	Double zinc ribbon; Region: DZR; pfam12773
990282005188	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
990282005189	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
990282005190	Walker A/P-loop; other site
990282005191	ATP binding site [chemical binding]; other site
990282005192	Q-loop/lid; other site
990282005193	ABC transporter signature motif; other site
990282005194	Walker B; other site
990282005195	D-loop; other site
990282005196	H-loop/switch region; other site
990282005197	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
990282005198	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
990282005199	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
990282005200	Walker A/P-loop; other site
990282005201	ATP binding site [chemical binding]; other site
990282005202	Q-loop/lid; other site
990282005203	ABC transporter signature motif; other site
990282005204	Walker B; other site
990282005205	D-loop; other site
990282005206	H-loop/switch region; other site
990282005207	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
990282005208	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
990282005209	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
990282005210	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282005211	dimer interface [polypeptide binding]; other site
990282005212	conserved gate region; other site
990282005213	ABC-ATPase subunit interface; other site
990282005214	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
990282005215	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282005216	dimer interface [polypeptide binding]; other site
990282005217	conserved gate region; other site
990282005218	putative PBP binding loops; other site
990282005219	ABC-ATPase subunit interface; other site
990282005220	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
990282005221	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
990282005222	peptide binding site [polypeptide binding]; other site
990282005223	hypothetical protein; Provisional; Region: PRK11111
990282005224	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
990282005225	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
990282005226	putative catalytic cysteine [active]
990282005227	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
990282005228	putative active site [active]
990282005229	metal binding site [ion binding]; metal-binding site
990282005230	thymidine kinase; Provisional; Region: PRK04296
990282005231	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
990282005232	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
990282005233	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
990282005234	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
990282005235	active site
990282005236	tetramer interface; other site
990282005237	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282005238	active site
990282005239	response regulator of RpoS; Provisional; Region: PRK10693
990282005240	phosphorylation site [posttranslational modification]
990282005241	intermolecular recognition site; other site
990282005242	dimerization interface [polypeptide binding]; other site
990282005243	hypothetical protein; Provisional; Region: PRK10279
990282005244	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
990282005245	active site
990282005246	nucleophile elbow; other site
990282005247	SEC-C motif; Region: SEC-C; pfam02810
990282005248	hypothetical protein; Provisional; Region: PRK04233
990282005249	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
990282005250	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
990282005251	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
990282005252	putative active site [active]
990282005253	putative substrate binding site [chemical binding]; other site
990282005254	putative cosubstrate binding site; other site
990282005255	catalytic site [active]
990282005256	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
990282005257	Sel1-like repeats; Region: SEL1; smart00671
990282005258	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
990282005259	Sel1-like repeats; Region: SEL1; smart00671
990282005260	Sel1-like repeats; Region: SEL1; smart00671
990282005261	Sel1-like repeats; Region: SEL1; smart00671
990282005262	Sel1-like repeats; Region: SEL1; smart00671
990282005263	Sel1-like repeats; Region: SEL1; smart00671
990282005264	Sel1-like repeats; Region: SEL1; smart00671
990282005265	Sel1-like repeats; Region: SEL1; smart00671
990282005266	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
990282005267	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
990282005268	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
990282005269	4Fe-4S binding domain; Region: Fer4; cl02805
990282005270	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
990282005271	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
990282005272	[4Fe-4S] binding site [ion binding]; other site
990282005273	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
990282005274	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
990282005275	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
990282005276	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
990282005277	molybdopterin cofactor binding site; other site
990282005278	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
990282005279	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
990282005280	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
990282005281	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
990282005282	dimerization interface [polypeptide binding]; other site
990282005283	Histidine kinase; Region: HisKA_3; pfam07730
990282005284	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282005285	ATP binding site [chemical binding]; other site
990282005286	Mg2+ binding site [ion binding]; other site
990282005287	G-X-G motif; other site
990282005288	transcriptional regulator NarL; Provisional; Region: PRK10651
990282005289	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282005290	active site
990282005291	phosphorylation site [posttranslational modification]
990282005292	intermolecular recognition site; other site
990282005293	dimerization interface [polypeptide binding]; other site
990282005294	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282005295	DNA binding residues [nucleotide binding]
990282005296	dimerization interface [polypeptide binding]; other site
990282005297	putative invasin; Provisional; Region: PRK10177
990282005298	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
990282005299	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
990282005300	cation transport regulator; Reviewed; Region: chaB; PRK09582
990282005301	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
990282005302	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
990282005303	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
990282005304	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
990282005305	hypothetical protein; Provisional; Region: PRK10941
990282005306	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
990282005307	hypothetical protein; Provisional; Region: PRK10278
990282005308	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
990282005309	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282005310	peptide chain release factor 1; Validated; Region: prfA; PRK00591
990282005311	This domain is found in peptide chain release factors; Region: PCRF; smart00937
990282005312	RF-1 domain; Region: RF-1; pfam00472
990282005313	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
990282005314	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
990282005315	tRNA; other site
990282005316	putative tRNA binding site [nucleotide binding]; other site
990282005317	putative NADP binding site [chemical binding]; other site
990282005318	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
990282005319	Outer membrane lipoprotein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: LolB; COG3017
990282005320	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
990282005321	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
990282005322	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
990282005323	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
990282005324	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
990282005325	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
990282005326	active site
990282005327	putative transporter; Provisional; Region: PRK11660
990282005328	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
990282005329	Sulfate transporter family; Region: Sulfate_transp; pfam00916
990282005330	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
990282005331	hypothetical protein; Provisional; Region: PRK10692
990282005332	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
990282005333	putative active site [active]
990282005334	catalytic residue [active]
990282005335	GTP-binding protein YchF; Reviewed; Region: PRK09601
990282005336	YchF GTPase; Region: YchF; cd01900
990282005337	G1 box; other site
990282005338	GTP/Mg2+ binding site [chemical binding]; other site
990282005339	Switch I region; other site
990282005340	G2 box; other site
990282005341	Switch II region; other site
990282005342	G3 box; other site
990282005343	G4 box; other site
990282005344	G5 box; other site
990282005345	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
990282005346	Protein of unknown function (DUF2743); Region: DUF2743; pfam10899
990282005347	Protein of unknown function (DUF4427); Region: DUF4427; pfam14468
990282005348	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
990282005349	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
990282005350	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
990282005351	hydrogenase 1 large subunit; Provisional; Region: PRK10170
990282005352	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
990282005353	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
990282005354	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
990282005355	putative substrate-binding site; other site
990282005356	nickel binding site [ion binding]; other site
990282005357	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
990282005358	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
990282005359	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
990282005360	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
990282005361	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
990282005362	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
990282005363	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
990282005364	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
990282005365	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
990282005366	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
990282005367	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
990282005368	NAD(P) binding site [chemical binding]; other site
990282005369	trehalase; Provisional; Region: treA; PRK13271
990282005370	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
990282005371	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
990282005372	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
990282005373	Flagellar regulator YcgR; Region: YcgR; pfam07317
990282005374	PilZ domain; Region: PilZ; pfam07238
990282005375	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
990282005376	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
990282005377	N-acetyl-D-glucosamine binding site [chemical binding]; other site
990282005378	catalytic residue [active]
990282005379	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
990282005380	dimer interface [polypeptide binding]; other site
990282005381	catalytic triad [active]
990282005382	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
990282005383	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
990282005384	TrkA-C domain; Region: TrkA_C; pfam02080
990282005385	Transporter associated domain; Region: CorC_HlyC; smart01091
990282005386	alanine racemase; Reviewed; Region: dadX; PRK03646
990282005387	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
990282005388	active site
990282005389	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
990282005390	substrate binding site [chemical binding]; other site
990282005391	catalytic residues [active]
990282005392	dimer interface [polypeptide binding]; other site
990282005393	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
990282005394	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
990282005395	SpoVR family protein; Provisional; Region: PRK11767
990282005396	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
990282005397	fatty acid metabolism regulator; Provisional; Region: PRK04984
990282005398	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282005399	DNA-binding site [nucleotide binding]; DNA binding site
990282005400	FadR C-terminal domain; Region: FadR_C; pfam07840
990282005401	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
990282005402	transmembrane helices; other site
990282005403	disulfide bond formation protein B; Provisional; Region: PRK01749
990282005404	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
990282005405	GnsA/GnsB family; Region: GnsAB; pfam08178
990282005406	hypothetical protein; Provisional; Region: PRK05170
990282005407	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
990282005408	hypothetical protein; Provisional; Region: PRK10691
990282005409	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
990282005410	septum formation inhibitor; Reviewed; Region: minC; PRK03511
990282005411	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
990282005412	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
990282005413	cell division inhibitor MinD; Provisional; Region: PRK10818
990282005414	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
990282005415	Switch I; other site
990282005416	Switch II; other site
990282005417	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
990282005418	ribonuclease D; Provisional; Region: PRK10829
990282005419	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
990282005420	catalytic site [active]
990282005421	putative active site [active]
990282005422	putative substrate binding site [chemical binding]; other site
990282005423	HRDC domain; Region: HRDC; cl02578
990282005424	Transposase IS200 like; Region: Y1_Tnp; pfam01797
990282005425	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
990282005426	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
990282005427	acyl-activating enzyme (AAE) consensus motif; other site
990282005428	putative AMP binding site [chemical binding]; other site
990282005429	putative active site [active]
990282005430	putative CoA binding site [chemical binding]; other site
990282005431	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
990282005432	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
990282005433	Glycoprotease family; Region: Peptidase_M22; pfam00814
990282005434	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
990282005435	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
990282005436	DEAD_2; Region: DEAD_2; pfam06733
990282005437	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
990282005438	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
990282005439	homotrimer interaction site [polypeptide binding]; other site
990282005440	putative active site [active]
990282005441	hypothetical protein; Provisional; Region: PRK05114
990282005442	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
990282005443	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
990282005444	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
990282005445	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
990282005446	putative active site [active]
990282005447	putative CoA binding site [chemical binding]; other site
990282005448	nudix motif; other site
990282005449	metal binding site [ion binding]; metal-binding site
990282005450	L-serine deaminase; Provisional; Region: PRK15023
990282005451	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
990282005452	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
990282005453	phage resistance protein; Provisional; Region: PRK10551
990282005454	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
990282005455	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
990282005456	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
990282005457	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
990282005458	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
990282005459	Transporter associated domain; Region: CorC_HlyC; smart01091
990282005460	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
990282005461	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
990282005462	active pocket/dimerization site; other site
990282005463	active site
990282005464	phosphorylation site [posttranslational modification]
990282005465	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
990282005466	active site
990282005467	phosphorylation site [posttranslational modification]
990282005468	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
990282005469	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
990282005470	hypothetical protein; Provisional; Region: PRK11469
990282005471	Domain of unknown function DUF; Region: DUF204; pfam02659
990282005472	Domain of unknown function DUF; Region: DUF204; pfam02659
990282005473	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
990282005474	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282005475	S-adenosylmethionine binding site [chemical binding]; other site
990282005476	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
990282005477	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
990282005478	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
990282005479	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
990282005480	DNA-binding site [nucleotide binding]; DNA binding site
990282005481	RNA-binding motif; other site
990282005482	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
990282005483	YebO-like protein; Region: YebO; pfam13974
990282005484	PhoPQ regulatory protein; Provisional; Region: PRK10299
990282005485	YobH-like protein; Region: YobH; pfam13996
990282005486	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
990282005487	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
990282005488	dimerization interface [polypeptide binding]; other site
990282005489	putative Zn2+ binding site [ion binding]; other site
990282005490	putative DNA binding site [nucleotide binding]; other site
990282005491	Bacterial transcriptional regulator; Region: IclR; pfam01614
990282005492	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282005493	Major Facilitator Superfamily; Region: MFS_1; pfam07690
990282005494	putative substrate translocation pore; other site
990282005495	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282005496	heat shock protein HtpX; Provisional; Region: PRK05457
990282005497	carboxy-terminal protease; Provisional; Region: PRK11186
990282005498	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
990282005499	protein binding site [polypeptide binding]; other site
990282005500	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
990282005501	Catalytic dyad [active]
990282005502	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
990282005503	ProP expression regulator; Provisional; Region: PRK04950
990282005504	ProQ/FINO family; Region: ProQ; pfam04352
990282005505	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
990282005506	GAF domain; Region: GAF_2; pfam13185
990282005507	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
990282005508	Paraquat-inducible protein A; Region: PqiA; pfam04403
990282005509	Paraquat-inducible protein A; Region: PqiA; pfam04403
990282005510	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
990282005511	mce related protein; Region: MCE; pfam02470
990282005512	mce related protein; Region: MCE; pfam02470
990282005513	mce related protein; Region: MCE; pfam02470
990282005514	mce related protein; Region: MCE; pfam02470
990282005515	mce related protein; Region: MCE; pfam02470
990282005516	mce related protein; Region: MCE; pfam02470
990282005517	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
990282005518	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
990282005519	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
990282005520	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
990282005521	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
990282005522	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
990282005523	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
990282005524	type III secretion protein SopE2; Provisional; Region: PRK15280
990282005525	Salmonella type III secretion SopE effector N-terminus; Region: SecIII_SopE_N; pfam05364
990282005526	SopE GEF domain; Region: SopE_GEF; pfam07487
990282005527	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
990282005528	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282005529	Coenzyme A binding pocket [chemical binding]; other site
990282005530	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
990282005531	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
990282005532	MULE transposase domain; Region: MULE; pfam10551
990282005533	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
990282005534	DNA binding site [nucleotide binding]
990282005535	active site
990282005536	Int/Topo IB signature motif; other site
990282005537	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
990282005538	EamA-like transporter family; Region: EamA; pfam00892
990282005539	EamA-like transporter family; Region: EamA; pfam00892
990282005540	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
990282005541	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
990282005542	DNA-binding interface [nucleotide binding]; DNA binding site
990282005543	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cl00019
990282005544	ADP-ribose binding site [chemical binding]; other site
990282005545	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
990282005546	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
990282005547	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
990282005548	Predicted chitinase [General function prediction only]; Region: COG3179
990282005549	exonuclease VIII; Reviewed; Region: PRK09709
990282005550	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
990282005551	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
990282005552	dimer interface [polypeptide binding]; other site
990282005553	active site
990282005554	Int/Topo IB signature motif; other site
990282005555	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
990282005556	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
990282005557	hypothetical protein; Provisional; Region: PRK10301
990282005558	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
990282005559	Predicted amidohydrolase [General function prediction only]; Region: COG0388
990282005560	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
990282005561	exodeoxyribonuclease X; Provisional; Region: PRK07983
990282005562	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
990282005563	active site
990282005564	catalytic site [active]
990282005565	substrate binding site [chemical binding]; other site
990282005566	protease 2; Provisional; Region: PRK10115
990282005567	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
990282005568	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
990282005569	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
990282005570	putative metal binding site [ion binding]; other site
990282005571	hypothetical protein; Provisional; Region: PRK13680
990282005572	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
990282005573	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
990282005574	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
990282005575	ATP-grasp domain; Region: ATP-grasp; pfam02222
990282005576	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
990282005577	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
990282005578	active site
990282005579	intersubunit interface [polypeptide binding]; other site
990282005580	catalytic residue [active]
990282005581	phosphogluconate dehydratase; Validated; Region: PRK09054
990282005582	6-phosphogluconate dehydratase; Region: edd; TIGR01196
990282005583	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
990282005584	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
990282005585	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
990282005586	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
990282005587	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
990282005588	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
990282005589	putative active site [active]
990282005590	pyruvate kinase; Provisional; Region: PRK05826
990282005591	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
990282005592	domain interfaces; other site
990282005593	active site
990282005594	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
990282005595	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
990282005596	putative acyl-acceptor binding pocket; other site
990282005597	putative peptidase; Provisional; Region: PRK11649
990282005598	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
990282005599	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
990282005600	Peptidase family M23; Region: Peptidase_M23; pfam01551
990282005601	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
990282005602	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
990282005603	metal binding site [ion binding]; metal-binding site
990282005604	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
990282005605	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
990282005606	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
990282005607	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
990282005608	ABC-ATPase subunit  interface; other site
990282005609	dimer interface [polypeptide binding]; other site
990282005610	putative PBP binding regions; other site
990282005611	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
990282005612	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282005613	Walker A motif; other site
990282005614	ATP binding site [chemical binding]; other site
990282005615	Walker B motif; other site
990282005616	arginine finger; other site
990282005617	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
990282005618	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
990282005619	RuvA N terminal domain; Region: RuvA_N; pfam01330
990282005620	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
990282005621	hypothetical protein; Provisional; Region: PRK11470
990282005622	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
990282005623	active site
990282005624	putative DNA-binding cleft [nucleotide binding]; other site
990282005625	dimer interface [polypeptide binding]; other site
990282005626	hypothetical protein; Validated; Region: PRK00110
990282005627	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
990282005628	nudix motif; other site
990282005629	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
990282005630	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
990282005631	dimer interface [polypeptide binding]; other site
990282005632	anticodon binding site; other site
990282005633	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
990282005634	homodimer interface [polypeptide binding]; other site
990282005635	motif 1; other site
990282005636	active site
990282005637	motif 2; other site
990282005638	GAD domain; Region: GAD; pfam02938
990282005639	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
990282005640	active site
990282005641	motif 3; other site
990282005642	Isochorismatase family; Region: Isochorismatase; pfam00857
990282005643	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
990282005644	catalytic triad [active]
990282005645	conserved cis-peptide bond; other site
990282005646	hypothetical protein; Provisional; Region: PRK10302
990282005647	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
990282005648	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282005649	S-adenosylmethionine binding site [chemical binding]; other site
990282005650	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282005651	S-adenosylmethionine binding site [chemical binding]; other site
990282005652	copper homeostasis protein CutC; Provisional; Region: PRK11572
990282005653	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
990282005654	putative metal binding site [ion binding]; other site
990282005655	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
990282005656	arginyl-tRNA synthetase; Region: argS; TIGR00456
990282005657	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
990282005658	active site
990282005659	HIGH motif; other site
990282005660	KMSK motif region; other site
990282005661	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
990282005662	tRNA binding surface [nucleotide binding]; other site
990282005663	anticodon binding site; other site
990282005664	penicillin-binding protein 2; Provisional; Region: PRK10795
990282005665	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
990282005666	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
990282005667	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
990282005668	Flagellar protein FlhE; Region: FlhE; pfam06366
990282005669	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
990282005670	FHIPEP family; Region: FHIPEP; pfam00771
990282005671	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
990282005672	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
990282005673	chemotaxis regulator CheZ; Provisional; Region: PRK11166
990282005674	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
990282005675	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282005676	active site
990282005677	phosphorylation site [posttranslational modification]
990282005678	intermolecular recognition site; other site
990282005679	dimerization interface [polypeptide binding]; other site
990282005680	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
990282005681	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282005682	active site
990282005683	phosphorylation site [posttranslational modification]
990282005684	intermolecular recognition site; other site
990282005685	dimerization interface [polypeptide binding]; other site
990282005686	CheB methylesterase; Region: CheB_methylest; pfam01339
990282005687	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
990282005688	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
990282005689	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282005690	S-adenosylmethionine binding site [chemical binding]; other site
990282005691	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
990282005692	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
990282005693	dimer interface [polypeptide binding]; other site
990282005694	ligand binding site [chemical binding]; other site
990282005695	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
990282005696	dimerization interface [polypeptide binding]; other site
990282005697	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
990282005698	dimer interface [polypeptide binding]; other site
990282005699	putative CheW interface [polypeptide binding]; other site
990282005700	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
990282005701	putative CheA interaction surface; other site
990282005702	chemotaxis protein CheA; Provisional; Region: PRK10547
990282005703	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
990282005704	putative binding surface; other site
990282005705	active site
990282005706	CheY binding; Region: CheY-binding; pfam09078
990282005707	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
990282005708	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282005709	ATP binding site [chemical binding]; other site
990282005710	Mg2+ binding site [ion binding]; other site
990282005711	G-X-G motif; other site
990282005712	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
990282005713	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
990282005714	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
990282005715	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
990282005716	ligand binding site [chemical binding]; other site
990282005717	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
990282005718	flagellar motor protein MotA; Validated; Region: PRK09110
990282005719	transcriptional activator FlhC; Provisional; Region: PRK12722
990282005720	transcriptional activator FlhD; Provisional; Region: PRK02909
990282005721	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
990282005722	Ligand Binding Site [chemical binding]; other site
990282005723	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
990282005724	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
990282005725	active site
990282005726	homotetramer interface [polypeptide binding]; other site
990282005727	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
990282005728	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
990282005729	DJ-1 family protein; Region: not_thiJ; TIGR01383
990282005730	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
990282005731	conserved cys residue [active]
990282005732	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
990282005733	Ferritin-like domain; Region: Ferritin; pfam00210
990282005734	ferroxidase diiron center [ion binding]; other site
990282005735	hypothetical protein; Provisional; Region: PRK09273
990282005736	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
990282005737	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
990282005738	YecR-like lipoprotein; Region: YecR; pfam13992
990282005739	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
990282005740	Ferritin-like domain; Region: Ferritin; pfam00210
990282005741	ferroxidase diiron center [ion binding]; other site
990282005742	probable metal-binding protein; Region: matur_matur; TIGR03853
990282005743	tyrosine transporter TyrP; Provisional; Region: PRK15132
990282005744	aromatic amino acid transport protein; Region: araaP; TIGR00837
990282005745	hypothetical protein; Provisional; Region: PRK10396
990282005746	yecA family protein; Region: ygfB_yecA; TIGR02292
990282005747	SEC-C motif; Region: SEC-C; pfam02810
990282005748	glucose-6-phosphate 1-dehydrogenase; Region: PLN02640
990282005749	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
990282005750	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
990282005751	NlpC/P60 family; Region: NLPC_P60; cl17555
990282005752	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
990282005753	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
990282005754	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
990282005755	GIY-YIG motif/motif A; other site
990282005756	active site
990282005757	catalytic site [active]
990282005758	putative DNA binding site [nucleotide binding]; other site
990282005759	metal binding site [ion binding]; metal-binding site
990282005760	UvrB/uvrC motif; Region: UVR; pfam02151
990282005761	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
990282005762	Helix-hairpin-helix motif; Region: HHH; pfam00633
990282005763	response regulator; Provisional; Region: PRK09483
990282005764	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282005765	active site
990282005766	phosphorylation site [posttranslational modification]
990282005767	intermolecular recognition site; other site
990282005768	dimerization interface [polypeptide binding]; other site
990282005769	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282005770	DNA binding residues [nucleotide binding]
990282005771	dimerization interface [polypeptide binding]; other site
990282005772	hypothetical protein; Provisional; Region: PRK10613
990282005773	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
990282005774	Autoinducer binding domain; Region: Autoind_bind; pfam03472
990282005775	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282005776	DNA binding residues [nucleotide binding]
990282005777	dimerization interface [polypeptide binding]; other site
990282005778	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
990282005779	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
990282005780	Walker A/P-loop; other site
990282005781	ATP binding site [chemical binding]; other site
990282005782	Q-loop/lid; other site
990282005783	ABC transporter signature motif; other site
990282005784	Walker B; other site
990282005785	D-loop; other site
990282005786	H-loop/switch region; other site
990282005787	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
990282005788	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
990282005789	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282005790	dimer interface [polypeptide binding]; other site
990282005791	conserved gate region; other site
990282005792	putative PBP binding loops; other site
990282005793	ABC-ATPase subunit interface; other site
990282005794	D-cysteine desulfhydrase; Validated; Region: PRK03910
990282005795	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
990282005796	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282005797	catalytic residue [active]
990282005798	cystine transporter subunit; Provisional; Region: PRK11260
990282005799	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
990282005800	substrate binding pocket [chemical binding]; other site
990282005801	membrane-bound complex binding site; other site
990282005802	hinge residues; other site
990282005803	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
990282005804	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
990282005805	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
990282005806	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
990282005807	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
990282005808	DNA binding residues [nucleotide binding]
990282005809	Transposase IS200 like; Region: Y1_Tnp; pfam01797
990282005810	flagellin; Validated; Region: PRK08026
990282005811	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
990282005812	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
990282005813	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
990282005814	flagellar capping protein; Reviewed; Region: fliD; PRK08032
990282005815	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
990282005816	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
990282005817	flagellar protein FliS; Validated; Region: fliS; PRK05685
990282005818	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
990282005819	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
990282005820	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
990282005821	active site
990282005822	Na/Ca binding site [ion binding]; other site
990282005823	catalytic site [active]
990282005824	lipoprotein; Provisional; Region: PRK10397
990282005825	putative inner membrane protein; Provisional; Region: PRK11099
990282005826	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
990282005827	CPxP  motif; other site
990282005828	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
990282005829	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
990282005830	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
990282005831	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
990282005832	flagellar motor switch protein FliG; Region: fliG; TIGR00207
990282005833	FliG C-terminal domain; Region: FliG_C; pfam01706
990282005834	flagellar assembly protein H; Validated; Region: fliH; PRK05687
990282005835	Flagellar assembly protein FliH; Region: FliH; pfam02108
990282005836	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
990282005837	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
990282005838	Walker A motif/ATP binding site; other site
990282005839	Walker B motif; other site
990282005840	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
990282005841	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
990282005842	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
990282005843	flagellar hook-length control protein; Provisional; Region: PRK10118
990282005844	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
990282005845	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
990282005846	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
990282005847	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
990282005848	flagellar motor switch protein; Validated; Region: fliN; PRK05698
990282005849	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
990282005850	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
990282005851	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
990282005852	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
990282005853	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
990282005854	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282005855	DNA binding residues [nucleotide binding]
990282005856	dimerization interface [polypeptide binding]; other site
990282005857	hypothetical protein; Provisional; Region: PRK10708
990282005858	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
990282005859	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
990282005860	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282005861	active site
990282005862	motif I; other site
990282005863	motif II; other site
990282005864	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
990282005865	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
990282005866	metal binding site [ion binding]; metal-binding site
990282005867	active site
990282005868	I-site; other site
990282005869	Uncharacterized small protein [Function unknown]; Region: COG5475
990282005870	hypothetical protein; Provisional; Region: PRK10062
990282005871	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
990282005872	EamA-like transporter family; Region: EamA; pfam00892
990282005873	EamA-like transporter family; Region: EamA; pfam00892
990282005874	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
990282005875	additional DNA contacts [nucleotide binding]; other site
990282005876	mismatch recognition site; other site
990282005877	active site
990282005878	zinc binding site [ion binding]; other site
990282005879	DNA intercalation site [nucleotide binding]; other site
990282005880	DNA cytosine methylase; Provisional; Region: PRK10458
990282005881	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
990282005882	cofactor binding site; other site
990282005883	DNA binding site [nucleotide binding]
990282005884	substrate interaction site [chemical binding]; other site
990282005885	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
990282005886	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
990282005887	Zn2+ binding site [ion binding]; other site
990282005888	Mg2+ binding site [ion binding]; other site
990282005889	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
990282005890	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
990282005891	trimer interface [polypeptide binding]; other site
990282005892	eyelet of channel; other site
990282005893	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
990282005894	DNA-binding site [nucleotide binding]; DNA binding site
990282005895	RNA-binding motif; other site
990282005896	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
990282005897	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
990282005898	active site
990282005899	DNA binding site [nucleotide binding]
990282005900	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
990282005901	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
990282005902	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
990282005903	Catalytic site [active]
990282005904	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
990282005905	DNA-binding interface [nucleotide binding]; DNA binding site
990282005906	type III secretion system protein; Provisional; Region: PRK15383
990282005907	non-LEE encoded effector protein NleB; Provisional; Region: PRK15382
990282005908	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
990282005909	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
990282005910	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
990282005911	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; pfam10076
990282005912	potential frameshift: common BLAST hit: gi|194736844|ref|YP_002117168.1| tail protein
990282005913	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
990282005914	Baseplate J-like protein; Region: Baseplate_J; cl01294
990282005915	Phage protein GP46; Region: GP46; pfam07409
990282005916	Bacteriophage Mu Gp45 protein; Region: Phage_Mu_Gp45; pfam06890
990282005917	Mu-like prophage tail protein gpP [General function prediction only]; Region: COG4379
990282005918	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
990282005919	Mu-like prophage DNA circulation protein [General function prediction only]; Region: COG4228
990282005920	DNA circulation protein N-terminus; Region: DNA_circ_N; pfam07157
990282005921	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
990282005922	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
990282005923	Phage tail tube protein; Region: Tail_tube; pfam10618
990282005924	Mu-like prophage tail sheath protein gpL [General function prediction only]; Region: COG4386
990282005925	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
990282005926	Protein of unknown function (DUF2635); Region: DUF2635; pfam10948
990282005927	Phage head-tail joining protein; Region: Phage_H_T_join; pfam05521
990282005928	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
990282005929	oligomerization interface [polypeptide binding]; other site
990282005930	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
990282005931	Phage capsid family; Region: Phage_capsid; pfam05065
990282005932	Caudovirus prohead protease; Region: Peptidase_U35; cl01521
990282005933	Phage-related protein [Function unknown]; Region: COG4695
990282005934	Phage portal protein; Region: Phage_portal; pfam04860
990282005935	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
990282005936	Phage terminase, small subunit; Region: Terminase_4; pfam05119
990282005937	KilA-N domain; Region: KilA-N; pfam04383
990282005938	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
990282005939	Phage holin family (Lysis protein S); Region: Phage_holin_3; pfam05106
990282005940	Protein of unknown function (DUF968); Region: DUF968; pfam06147
990282005941	KilA-N domain; Region: KilA-N; pfam04383
990282005942	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
990282005943	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; pfam05869
990282005944	Helix-turn-helix domain; Region: HTH_36; pfam13730
990282005945	Ash protein family; Region: Phage_ASH; pfam10554
990282005946	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
990282005947	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
990282005948	non-specific DNA binding site [nucleotide binding]; other site
990282005949	salt bridge; other site
990282005950	sequence-specific DNA binding site [nucleotide binding]; other site
990282005951	Predicted transcriptional regulator [Transcription]; Region: COG2932
990282005952	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
990282005953	non-specific DNA binding site [nucleotide binding]; other site
990282005954	salt bridge; other site
990282005955	sequence-specific DNA binding site [nucleotide binding]; other site
990282005956	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
990282005957	Catalytic site [active]
990282005958	Uncharacterized conserved protein (DUF2303); Region: DUF2303; pfam10065
990282005959	HD domain; Region: HD_3; cl17350
990282005960	Protein of unknown function DUF262; Region: DUF262; pfam03235
990282005961	Uncharacterized conserved protein [Function unknown]; Region: COG1479
990282005962	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
990282005963	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
990282005964	active site
990282005965	catalytic site [active]
990282005966	substrate binding site [chemical binding]; other site
990282005967	Domain of unknown function (DUF4224); Region: DUF4224; pfam13986
990282005968	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
990282005969	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
990282005970	dimer interface [polypeptide binding]; other site
990282005971	active site
990282005972	Int/Topo IB signature motif; other site
990282005973	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
990282005974	putative protease; Region: PHA00666
990282005975	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
990282005976	Integrase; Region: Integrase_1; pfam12835
990282005977	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
990282005978	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
990282005979	Sel1-like repeats; Region: SEL1; smart00671
990282005980	Sel1-like repeats; Region: SEL1; smart00671
990282005981	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
990282005982	AMP nucleosidase; Provisional; Region: PRK08292
990282005983	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
990282005984	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
990282005985	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
990282005986	MATE family multidrug exporter; Provisional; Region: PRK10189
990282005987	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
990282005988	L,D-transpeptidase; Provisional; Region: PRK10190
990282005989	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
990282005990	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
990282005991	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
990282005992	putative dimer interface [polypeptide binding]; other site
990282005993	active site pocket [active]
990282005994	putative cataytic base [active]
990282005995	cobalamin synthase; Reviewed; Region: cobS; PRK00235
990282005996	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
990282005997	homotrimer interface [polypeptide binding]; other site
990282005998	Walker A motif; other site
990282005999	GTP binding site [chemical binding]; other site
990282006000	Walker B motif; other site
990282006001	cobyric acid synthase; Provisional; Region: PRK00784
990282006002	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
990282006003	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
990282006004	catalytic triad [active]
990282006005	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
990282006006	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
990282006007	Walker A/P-loop; other site
990282006008	ATP binding site [chemical binding]; other site
990282006009	Q-loop/lid; other site
990282006010	ABC transporter signature motif; other site
990282006011	Walker B; other site
990282006012	D-loop; other site
990282006013	H-loop/switch region; other site
990282006014	cobalt transport protein CbiQ; Provisional; Region: PRK15485
990282006015	cobalt transport protein CbiN; Provisional; Region: PRK02898
990282006016	cobalt transport protein CbiM; Validated; Region: PRK08319
990282006017	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
990282006018	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
990282006019	active site
990282006020	SAM binding site [chemical binding]; other site
990282006021	homodimer interface [polypeptide binding]; other site
990282006022	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
990282006023	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
990282006024	active site
990282006025	C-terminal domain interface [polypeptide binding]; other site
990282006026	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
990282006027	active site
990282006028	N-terminal domain interface [polypeptide binding]; other site
990282006029	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
990282006030	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
990282006031	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
990282006032	active site
990282006033	SAM binding site [chemical binding]; other site
990282006034	homodimer interface [polypeptide binding]; other site
990282006035	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
990282006036	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
990282006037	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
990282006038	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
990282006039	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
990282006040	active site
990282006041	SAM binding site [chemical binding]; other site
990282006042	homodimer interface [polypeptide binding]; other site
990282006043	cobalt-precorrin-6Y C(15)-methyltransferase; Validated; Region: PRK08287
990282006044	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282006045	S-adenosylmethionine binding site [chemical binding]; other site
990282006046	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
990282006047	active site
990282006048	putative homodimer interface [polypeptide binding]; other site
990282006049	SAM binding site [chemical binding]; other site
990282006050	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
990282006051	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
990282006052	Precorrin-8X methylmutase; Region: CbiC; pfam02570
990282006053	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
990282006054	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
990282006055	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
990282006056	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
990282006057	catalytic triad [active]
990282006058	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
990282006059	Sensory domain found in PocR; Region: PocR; pfam10114
990282006060	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282006061	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
990282006062	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282006063	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
990282006064	amphipathic channel; other site
990282006065	Asn-Pro-Ala signature motifs; other site
990282006066	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
990282006067	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
990282006068	Hexamer interface [polypeptide binding]; other site
990282006069	Putative hexagonal pore residue; other site
990282006070	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutL; COG4816
990282006071	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
990282006072	putative hexamer interface [polypeptide binding]; other site
990282006073	putative hexagonal pore; other site
990282006074	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
990282006075	putative hexamer interface [polypeptide binding]; other site
990282006076	putative hexagonal pore; other site
990282006077	Propanediol dehydratase, large subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduC; COG4909
990282006078	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
990282006079	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
990282006080	alpha-beta subunit interface [polypeptide binding]; other site
990282006081	alpha-gamma subunit interface [polypeptide binding]; other site
990282006082	active site
990282006083	substrate and K+ binding site; other site
990282006084	K+ binding site [ion binding]; other site
990282006085	cobalamin binding site [chemical binding]; other site
990282006086	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
990282006087	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
990282006088	Cell division protein FtsA; Region: FtsA; cl17206
990282006089	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
990282006090	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
990282006091	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
990282006092	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
990282006093	Hexamer interface [polypeptide binding]; other site
990282006094	Putative hexagonal pore residue; other site
990282006095	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
990282006096	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
990282006097	putative hexamer interface [polypeptide binding]; other site
990282006098	putative hexagonal pore; other site
990282006099	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
990282006100	Propanediol utilisation protein PduL; Region: PduL; pfam06130
990282006101	Propanediol utilisation protein PduL; Region: PduL; pfam06130
990282006102	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
990282006103	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
990282006104	Hexamer/Pentamer interface [polypeptide binding]; other site
990282006105	central pore; other site
990282006106	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
990282006107	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
990282006108	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
990282006109	putative catalytic cysteine [active]
990282006110	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
990282006111	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
990282006112	putative active site [active]
990282006113	metal binding site [ion binding]; metal-binding site
990282006114	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
990282006115	SLBB domain; Region: SLBB; pfam10531
990282006116	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
990282006117	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
990282006118	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
990282006119	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
990282006120	putative hexamer interface [polypeptide binding]; other site
990282006121	putative hexagonal pore; other site
990282006122	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
990282006123	putative hexamer interface [polypeptide binding]; other site
990282006124	putative hexagonal pore; other site
990282006125	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
990282006126	putative hexamer interface [polypeptide binding]; other site
990282006127	putative hexagonal pore; other site
990282006128	Ethanolamine utilisation - propanediol utilisation; Region: PduV-EutP; pfam10662
990282006129	G3 box; other site
990282006130	Switch II region; other site
990282006131	GTP/Mg2+ binding site [chemical binding]; other site
990282006132	G4 box; other site
990282006133	G5 box; other site
990282006134	propionate kinase; Reviewed; Region: PRK12397
990282006135	propionate/acetate kinase; Provisional; Region: PRK12379
990282006136	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
990282006137	hypothetical protein; Provisional; Region: PRK05423
990282006138	Predicted membrane protein [Function unknown]; Region: COG1289
990282006139	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
990282006140	DNA gyrase inhibitor; Provisional; Region: PRK10016
990282006141	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
990282006142	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
990282006143	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
990282006144	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
990282006145	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
990282006146	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
990282006147	4Fe-4S binding domain; Region: Fer4; cl02805
990282006148	thiosulfate reductase PhsA; Provisional; Region: PRK15488
990282006149	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
990282006150	The MopB_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_Thiosulfate-R-like; cd02755
990282006151	putative [Fe4-S4] binding site [ion binding]; other site
990282006152	putative molybdopterin cofactor binding site [chemical binding]; other site
990282006153	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
990282006154	The MopB_CT_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_CT_Thiosulfate-R-like; cd02778
990282006155	putative molybdopterin cofactor binding site; other site
990282006156	E3 ubiquitin-protein ligase SopA; Provisional; Region: PRK15377
990282006157	SopA-like central domain; Region: SopA; pfam13981
990282006158	SopA-like catalytic domain; Region: SopA_C; pfam13979
990282006159	exonuclease I; Provisional; Region: sbcB; PRK11779
990282006160	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
990282006161	active site
990282006162	catalytic site [active]
990282006163	substrate binding site [chemical binding]; other site
990282006164	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
990282006165	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
990282006166	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282006167	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
990282006168	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
990282006169	dimerization interface [polypeptide binding]; other site
990282006170	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
990282006171	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
990282006172	putative NAD(P) binding site [chemical binding]; other site
990282006173	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
990282006174	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
990282006175	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
990282006176	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
990282006177	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
990282006178	NAD binding site [chemical binding]; other site
990282006179	dimerization interface [polypeptide binding]; other site
990282006180	product binding site; other site
990282006181	substrate binding site [chemical binding]; other site
990282006182	zinc binding site [ion binding]; other site
990282006183	catalytic residues [active]
990282006184	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
990282006185	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
990282006186	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282006187	homodimer interface [polypeptide binding]; other site
990282006188	catalytic residue [active]
990282006189	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
990282006190	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282006191	active site
990282006192	motif I; other site
990282006193	motif II; other site
990282006194	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
990282006195	putative active site pocket [active]
990282006196	4-fold oligomerization interface [polypeptide binding]; other site
990282006197	metal binding residues [ion binding]; metal-binding site
990282006198	3-fold/trimer interface [polypeptide binding]; other site
990282006199	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
990282006200	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
990282006201	putative active site [active]
990282006202	oxyanion strand; other site
990282006203	catalytic triad [active]
990282006204	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
990282006205	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
990282006206	catalytic residues [active]
990282006207	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
990282006208	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
990282006209	substrate binding site [chemical binding]; other site
990282006210	glutamase interaction surface [polypeptide binding]; other site
990282006211	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
990282006212	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
990282006213	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
990282006214	metal binding site [ion binding]; metal-binding site
990282006215	chain length determinant protein WzzB; Provisional; Region: PRK15471
990282006216	Chain length determinant protein; Region: Wzz; pfam02706
990282006217	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
990282006218	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
990282006219	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
990282006220	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
990282006221	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
990282006222	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
990282006223	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
990282006224	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
990282006225	undecaprenyl-phosphate galactose phosphotransferase; Provisional; Region: PRK15204
990282006226	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
990282006227	Bacterial sugar transferase; Region: Bac_transf; pfam02397
990282006228	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
990282006229	ManB is a bacterial phosphomannomutase (PMM) that catalyzes the conversion of mannose 6-phosphate to mannose-1-phosphate in the second of three steps in the GDP-mannose pathway, in which GDP-D-mannose is synthesized from fructose-6-phosphate. In...; Region: ManB; cd03088
990282006230	active site
990282006231	substrate binding site [chemical binding]; other site
990282006232	metal binding site [ion binding]; metal-binding site
990282006233	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
990282006234	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
990282006235	Substrate binding site; other site
990282006236	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
990282006237	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
990282006238	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
990282006239	active site
990282006240	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
990282006241	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
990282006242	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
990282006243	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
990282006244	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
990282006245	active site
990282006246	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cd12082
990282006247	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
990282006248	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
990282006249	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
990282006250	NAD(P) binding site [chemical binding]; other site
990282006251	active site
990282006252	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
990282006253	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
990282006254	inhibitor-cofactor binding pocket; inhibition site
990282006255	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282006256	catalytic residue [active]
990282006257	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
990282006258	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
990282006259	NAD binding site [chemical binding]; other site
990282006260	homotetramer interface [polypeptide binding]; other site
990282006261	homodimer interface [polypeptide binding]; other site
990282006262	substrate binding site [chemical binding]; other site
990282006263	active site
990282006264	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
990282006265	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
990282006266	substrate binding site; other site
990282006267	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
990282006268	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
990282006269	catalytic loop [active]
990282006270	iron binding site [ion binding]; other site
990282006271	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
990282006272	FAD binding pocket [chemical binding]; other site
990282006273	FAD binding motif [chemical binding]; other site
990282006274	phosphate binding motif [ion binding]; other site
990282006275	beta-alpha-beta structure motif; other site
990282006276	NAD binding pocket [chemical binding]; other site
990282006277	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
990282006278	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
990282006279	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
990282006280	substrate binding site; other site
990282006281	tetramer interface; other site
990282006282	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
990282006283	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
990282006284	NADP binding site [chemical binding]; other site
990282006285	active site
990282006286	putative substrate binding site [chemical binding]; other site
990282006287	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
990282006288	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
990282006289	NAD binding site [chemical binding]; other site
990282006290	substrate binding site [chemical binding]; other site
990282006291	homodimer interface [polypeptide binding]; other site
990282006292	active site
990282006293	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
990282006294	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
990282006295	active site
990282006296	tetramer interface; other site
990282006297	colanic acid biosynthesis protein WcaM; Region: WcaM; TIGR04004
990282006298	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
990282006299	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
990282006300	putative ADP-binding pocket [chemical binding]; other site
990282006301	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
990282006302	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
990282006303	colanic acid exporter; Provisional; Region: PRK10459
990282006304	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
990282006305	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
990282006306	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
990282006307	phosphomannomutase CpsG; Provisional; Region: PRK15414
990282006308	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
990282006309	active site
990282006310	substrate binding site [chemical binding]; other site
990282006311	metal binding site [ion binding]; metal-binding site
990282006312	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
990282006313	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
990282006314	Substrate binding site; other site
990282006315	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
990282006316	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
990282006317	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
990282006318	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
990282006319	active site
990282006320	GDP-Mannose binding site [chemical binding]; other site
990282006321	dimer interface [polypeptide binding]; other site
990282006322	modified nudix motif
990282006323	metal binding site [ion binding]; metal-binding site
990282006324	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
990282006325	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
990282006326	NADP binding site [chemical binding]; other site
990282006327	active site
990282006328	putative substrate binding site [chemical binding]; other site
990282006329	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
990282006330	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
990282006331	NADP-binding site; other site
990282006332	homotetramer interface [polypeptide binding]; other site
990282006333	substrate binding site [chemical binding]; other site
990282006334	homodimer interface [polypeptide binding]; other site
990282006335	active site
990282006336	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
990282006337	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
990282006338	putative trimer interface [polypeptide binding]; other site
990282006339	putative active site [active]
990282006340	putative substrate binding site [chemical binding]; other site
990282006341	putative CoA binding site [chemical binding]; other site
990282006342	putative glycosyl transferase; Provisional; Region: PRK10063
990282006343	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
990282006344	metal-binding site
990282006345	putative colanic acid biosynthesis protein; Provisional; Region: wcaD; cl08075
990282006346	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
990282006347	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
990282006348	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
990282006349	putative acyl transferase; Provisional; Region: PRK10191
990282006350	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
990282006351	trimer interface [polypeptide binding]; other site
990282006352	active site
990282006353	substrate binding site [chemical binding]; other site
990282006354	CoA binding site [chemical binding]; other site
990282006355	putative glycosyl transferase; Provisional; Region: PRK10018
990282006356	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
990282006357	active site
990282006358	tyrosine kinase; Provisional; Region: PRK11519
990282006359	Chain length determinant protein; Region: Wzz; pfam02706
990282006360	Chain length determinant protein; Region: Wzz; cl15801
990282006361	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
990282006362	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
990282006363	Low molecular weight phosphatase family; Region: LMWPc; cd00115
990282006364	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
990282006365	active site
990282006366	polysaccharide export protein Wza; Provisional; Region: PRK15078
990282006367	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
990282006368	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
990282006369	FOG: CBS domain [General function prediction only]; Region: COG0517
990282006370	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
990282006371	Transporter associated domain; Region: CorC_HlyC; smart01091
990282006372	putative assembly protein; Provisional; Region: PRK10833
990282006373	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
990282006374	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
990282006375	trimer interface [polypeptide binding]; other site
990282006376	active site
990282006377	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
990282006378	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
990282006379	ATP-binding site [chemical binding]; other site
990282006380	Sugar specificity; other site
990282006381	Pyrimidine base specificity; other site
990282006382	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
990282006383	PAS domain S-box; Region: sensory_box; TIGR00229
990282006384	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
990282006385	putative active site [active]
990282006386	heme pocket [chemical binding]; other site
990282006387	PAS domain S-box; Region: sensory_box; TIGR00229
990282006388	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
990282006389	putative active site [active]
990282006390	heme pocket [chemical binding]; other site
990282006391	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
990282006392	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
990282006393	metal binding site [ion binding]; metal-binding site
990282006394	active site
990282006395	I-site; other site
990282006396	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
990282006397	putative chaperone; Provisional; Region: PRK11678
990282006398	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
990282006399	nucleotide binding site [chemical binding]; other site
990282006400	putative NEF/HSP70 interaction site [polypeptide binding]; other site
990282006401	SBD interface [polypeptide binding]; other site
990282006402	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
990282006403	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
990282006404	HlyD family secretion protein; Region: HlyD_3; pfam13437
990282006405	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
990282006406	Protein export membrane protein; Region: SecD_SecF; cl14618
990282006407	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
990282006408	putative transporter; Provisional; Region: PRK10504
990282006409	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282006410	putative substrate translocation pore; other site
990282006411	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
990282006412	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
990282006413	dimerization interface [polypeptide binding]; other site
990282006414	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282006415	dimer interface [polypeptide binding]; other site
990282006416	phosphorylation site [posttranslational modification]
990282006417	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282006418	ATP binding site [chemical binding]; other site
990282006419	Mg2+ binding site [ion binding]; other site
990282006420	G-X-G motif; other site
990282006421	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
990282006422	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282006423	active site
990282006424	phosphorylation site [posttranslational modification]
990282006425	intermolecular recognition site; other site
990282006426	dimerization interface [polypeptide binding]; other site
990282006427	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
990282006428	DNA binding site [nucleotide binding]
990282006429	PcfJ-like protein; Region: PcfJ; pfam14284
990282006430	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
990282006431	Domain of unknown function (DUF4034); Region: DUF4034; pfam13226
990282006432	putative protease; Provisional; Region: PRK15452
990282006433	Peptidase family U32; Region: Peptidase_U32; pfam01136
990282006434	type III secretion system protein; Provisional; Region: PRK15383
990282006435	non-LEE encoded effector protein NleB; Provisional; Region: PRK15382
990282006436	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
990282006437	lipid kinase; Reviewed; Region: PRK13054
990282006438	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
990282006439	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
990282006440	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
990282006441	putative active site; other site
990282006442	catalytic residue [active]
990282006443	nucleoside transporter; Region: 2A0110; TIGR00889
990282006444	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282006445	putative substrate translocation pore; other site
990282006446	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
990282006447	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
990282006448	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
990282006449	substrate binding site [chemical binding]; other site
990282006450	ATP binding site [chemical binding]; other site
990282006451	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
990282006452	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282006453	DNA-binding site [nucleotide binding]; DNA binding site
990282006454	UTRA domain; Region: UTRA; pfam07702
990282006455	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
990282006456	dimer interface [polypeptide binding]; other site
990282006457	substrate binding site [chemical binding]; other site
990282006458	ATP binding site [chemical binding]; other site
990282006459	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
990282006460	substrate binding site [chemical binding]; other site
990282006461	multimerization interface [polypeptide binding]; other site
990282006462	ATP binding site [chemical binding]; other site
990282006463	Predicted integral membrane protein [Function unknown]; Region: COG5455
990282006464	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
990282006465	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
990282006466	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
990282006467	PapC N-terminal domain; Region: PapC_N; pfam13954
990282006468	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
990282006469	PapC C-terminal domain; Region: PapC_C; pfam13953
990282006470	fimbrial chaperone protein PegB; Provisional; Region: PRK15218
990282006471	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
990282006472	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
990282006473	fimbrial chaperone protein; Provisional; Region: PRK15220
990282006474	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
990282006475	antiporter inner membrane protein; Provisional; Region: PRK11670
990282006476	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
990282006477	Walker A motif; other site
990282006478	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
990282006479	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
990282006480	active site
990282006481	HIGH motif; other site
990282006482	KMSKS motif; other site
990282006483	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
990282006484	tRNA binding surface [nucleotide binding]; other site
990282006485	anticodon binding site; other site
990282006486	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
990282006487	dimer interface [polypeptide binding]; other site
990282006488	putative tRNA-binding site [nucleotide binding]; other site
990282006489	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
990282006490	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
990282006491	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
990282006492	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
990282006493	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
990282006494	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
990282006495	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282006496	active site
990282006497	phosphorylation site [posttranslational modification]
990282006498	intermolecular recognition site; other site
990282006499	dimerization interface [polypeptide binding]; other site
990282006500	LytTr DNA-binding domain; Region: LytTR; pfam04397
990282006501	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
990282006502	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
990282006503	GAF domain; Region: GAF; pfam01590
990282006504	Histidine kinase; Region: His_kinase; pfam06580
990282006505	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282006506	ATP binding site [chemical binding]; other site
990282006507	Mg2+ binding site [ion binding]; other site
990282006508	G-X-G motif; other site
990282006509	transcriptional regulator MirA; Provisional; Region: PRK15043
990282006510	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
990282006511	DNA binding residues [nucleotide binding]
990282006512	hypothetical protein; Provisional; Region: PRK13681
990282006513	ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism]; Region: OpuBB; COG1174
990282006514	putative PBP binding loops; other site
990282006515	ABC-ATPase subunit interface; other site
990282006516	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
990282006517	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
990282006518	Walker A/P-loop; other site
990282006519	ATP binding site [chemical binding]; other site
990282006520	Q-loop/lid; other site
990282006521	ABC transporter signature motif; other site
990282006522	Walker B; other site
990282006523	D-loop; other site
990282006524	H-loop/switch region; other site
990282006525	CBS domain; Region: CBS; pfam00571
990282006526	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282006527	dimer interface [polypeptide binding]; other site
990282006528	conserved gate region; other site
990282006529	ABC-ATPase subunit interface; other site
990282006530	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
990282006531	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
990282006532	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
990282006533	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
990282006534	D-lactate dehydrogenase; Provisional; Region: PRK11183
990282006535	FAD binding domain; Region: FAD_binding_4; pfam01565
990282006536	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
990282006537	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
990282006538	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
990282006539	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
990282006540	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
990282006541	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
990282006542	oxidoreductase; Provisional; Region: PRK12743
990282006543	classical (c) SDRs; Region: SDR_c; cd05233
990282006544	NAD(P) binding site [chemical binding]; other site
990282006545	active site
990282006546	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
990282006547	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
990282006548	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
990282006549	FMN binding site [chemical binding]; other site
990282006550	active site
990282006551	catalytic residues [active]
990282006552	substrate binding site [chemical binding]; other site
990282006553	salicylate hydroxylase; Provisional; Region: PRK08163
990282006554	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
990282006555	GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042
990282006556	maleylacetoacetate isomerase; Region: maiA; TIGR01262
990282006557	C-terminal domain interface [polypeptide binding]; other site
990282006558	GSH binding site (G-site) [chemical binding]; other site
990282006559	putative dimer interface [polypeptide binding]; other site
990282006560	C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191
990282006561	dimer interface [polypeptide binding]; other site
990282006562	N-terminal domain interface [polypeptide binding]; other site
990282006563	maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site
990282006564	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
990282006565	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
990282006566	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
990282006567	Cupin domain; Region: Cupin_2; pfam07883
990282006568	Cupin domain; Region: Cupin_2; pfam07883
990282006569	benzoate transport; Region: 2A0115; TIGR00895
990282006570	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282006571	putative substrate translocation pore; other site
990282006572	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
990282006573	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282006574	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
990282006575	dimerization interface [polypeptide binding]; other site
990282006576	hypothetical protein; Provisional; Region: PRK01821
990282006577	hypothetical protein; Provisional; Region: PRK10711
990282006578	cytidine deaminase; Provisional; Region: PRK09027
990282006579	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
990282006580	active site
990282006581	catalytic motif [active]
990282006582	Zn binding site [ion binding]; other site
990282006583	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
990282006584	active site
990282006585	catalytic motif [active]
990282006586	Zn binding site [ion binding]; other site
990282006587	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
990282006588	putative active site [active]
990282006589	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
990282006590	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
990282006591	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
990282006592	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
990282006593	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
990282006594	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
990282006595	homodimer interface [polypeptide binding]; other site
990282006596	active site
990282006597	FMN binding site [chemical binding]; other site
990282006598	substrate binding site [chemical binding]; other site
990282006599	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
990282006600	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
990282006601	TM-ABC transporter signature motif; other site
990282006602	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
990282006603	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
990282006604	Walker A/P-loop; other site
990282006605	ATP binding site [chemical binding]; other site
990282006606	Q-loop/lid; other site
990282006607	ABC transporter signature motif; other site
990282006608	Walker B; other site
990282006609	D-loop; other site
990282006610	H-loop/switch region; other site
990282006611	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
990282006612	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
990282006613	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
990282006614	ligand binding site [chemical binding]; other site
990282006615	calcium binding site [ion binding]; other site
990282006616	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
990282006617	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
990282006618	DNA binding site [nucleotide binding]
990282006619	domain linker motif; other site
990282006620	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
990282006621	dimerization interface (closed form) [polypeptide binding]; other site
990282006622	ligand binding site [chemical binding]; other site
990282006623	Predicted membrane protein [Function unknown]; Region: COG2311
990282006624	hypothetical protein; Provisional; Region: PRK10835
990282006625	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
990282006626	GTP cyclohydrolase I; Provisional; Region: PLN03044
990282006627	active site
990282006628	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
990282006629	S-formylglutathione hydrolase; Region: PLN02442
990282006630	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
990282006631	non-specific DNA binding site [nucleotide binding]; other site
990282006632	salt bridge; other site
990282006633	sequence-specific DNA binding site [nucleotide binding]; other site
990282006634	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
990282006635	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
990282006636	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
990282006637	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
990282006638	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
990282006639	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282006640	motif II; other site
990282006641	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
990282006642	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282006643	putative substrate translocation pore; other site
990282006644	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
990282006645	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
990282006646	N-terminal plug; other site
990282006647	ligand-binding site [chemical binding]; other site
990282006648	lysine transporter; Provisional; Region: PRK10836
990282006649	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
990282006650	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282006651	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
990282006652	putative dimerization interface [polypeptide binding]; other site
990282006653	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
990282006654	endonuclease IV; Provisional; Region: PRK01060
990282006655	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
990282006656	AP (apurinic/apyrimidinic) site pocket; other site
990282006657	DNA interaction; other site
990282006658	Metal-binding active site; metal-binding site
990282006659	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
990282006660	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
990282006661	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
990282006662	active site
990282006663	P-loop; other site
990282006664	phosphorylation site [posttranslational modification]
990282006665	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
990282006666	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
990282006667	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
990282006668	putative substrate binding site [chemical binding]; other site
990282006669	putative ATP binding site [chemical binding]; other site
990282006670	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
990282006671	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
990282006672	active site
990282006673	phosphorylation site [posttranslational modification]
990282006674	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
990282006675	dimerization domain swap beta strand [polypeptide binding]; other site
990282006676	regulatory protein interface [polypeptide binding]; other site
990282006677	active site
990282006678	regulatory phosphorylation site [posttranslational modification]; other site
990282006679	sugar efflux transporter B; Provisional; Region: PRK15011
990282006680	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282006681	putative substrate translocation pore; other site
990282006682	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
990282006683	elongation factor P; Provisional; Region: PRK04542
990282006684	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
990282006685	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
990282006686	RNA binding site [nucleotide binding]; other site
990282006687	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
990282006688	RNA binding site [nucleotide binding]; other site
990282006689	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
990282006690	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
990282006691	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
990282006692	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
990282006693	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
990282006694	active site
990282006695	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
990282006696	NlpC/P60 family; Region: NLPC_P60; pfam00877
990282006697	phage resistance protein; Provisional; Region: PRK10551
990282006698	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
990282006699	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
990282006700	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
990282006701	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
990282006702	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
990282006703	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282006704	dimer interface [polypeptide binding]; other site
990282006705	conserved gate region; other site
990282006706	putative PBP binding loops; other site
990282006707	ABC-ATPase subunit interface; other site
990282006708	microcin C ABC transporter permease; Provisional; Region: PRK15021
990282006709	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282006710	dimer interface [polypeptide binding]; other site
990282006711	conserved gate region; other site
990282006712	ABC-ATPase subunit interface; other site
990282006713	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
990282006714	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
990282006715	Walker A/P-loop; other site
990282006716	ATP binding site [chemical binding]; other site
990282006717	Q-loop/lid; other site
990282006718	ABC transporter signature motif; other site
990282006719	Walker B; other site
990282006720	D-loop; other site
990282006721	H-loop/switch region; other site
990282006722	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
990282006723	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
990282006724	Walker A/P-loop; other site
990282006725	ATP binding site [chemical binding]; other site
990282006726	Q-loop/lid; other site
990282006727	ABC transporter signature motif; other site
990282006728	Walker B; other site
990282006729	D-loop; other site
990282006730	H-loop/switch region; other site
990282006731	hypothetical protein; Provisional; Region: PRK11835
990282006732	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282006733	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
990282006734	putative substrate translocation pore; other site
990282006735	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
990282006736	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
990282006737	RNA binding surface [nucleotide binding]; other site
990282006738	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
990282006739	active site
990282006740	uracil binding [chemical binding]; other site
990282006741	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
990282006742	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
990282006743	ATP binding site [chemical binding]; other site
990282006744	putative Mg++ binding site [ion binding]; other site
990282006745	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
990282006746	nucleotide binding region [chemical binding]; other site
990282006747	ATP-binding site [chemical binding]; other site
990282006748	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
990282006749	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
990282006750	5S rRNA interface [nucleotide binding]; other site
990282006751	CTC domain interface [polypeptide binding]; other site
990282006752	L16 interface [polypeptide binding]; other site
990282006753	Nucleoid-associated protein [General function prediction only]; Region: COG3081
990282006754	nucleoid-associated protein NdpA; Validated; Region: PRK00378
990282006755	hypothetical protein; Provisional; Region: PRK13689
990282006756	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
990282006757	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
990282006758	Sulfatase; Region: Sulfatase; cl17466
990282006759	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
990282006760	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
990282006761	Catalytic site [active]
990282006762	DinI-like family; Region: DinI; cl11630
990282006763	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
990282006764	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
990282006765	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
990282006766	Phage T4 tail fibre; Region: Phage_T4_gp36; pfam03903
990282006767	Phage head maturation protease [General function prediction only]; Region: COG3740
990282006768	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
990282006769	Phage-related protein [Function unknown]; Region: COG4695; cl01923
990282006770	Predicted P-loop ATPase [General function prediction only]; Region: COG4928
990282006771	KAP family P-loop domain; Region: KAP_NTPase; pfam07693
990282006772	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
990282006773	Protein of unknown function (DUF968); Region: DUF968; pfam06147
990282006774	E3 ubiquitin-protein ligase SspH2; Provisional; Region: PRK15387
990282006775	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
990282006776	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
990282006777	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
990282006778	Leucine-rich repeats; other site
990282006779	Substrate binding site [chemical binding]; other site
990282006780	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
990282006781	DinI-like family; Region: DinI; cl11630
990282006782	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
990282006783	transcriptional regulator NarP; Provisional; Region: PRK10403
990282006784	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282006785	active site
990282006786	phosphorylation site [posttranslational modification]
990282006787	intermolecular recognition site; other site
990282006788	dimerization interface [polypeptide binding]; other site
990282006789	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282006790	DNA binding residues [nucleotide binding]
990282006791	dimerization interface [polypeptide binding]; other site
990282006792	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
990282006793	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
990282006794	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
990282006795	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
990282006796	catalytic residues [active]
990282006797	central insert; other site
990282006798	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
990282006799	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
990282006800	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
990282006801	heme exporter protein CcmC; Region: ccmC; TIGR01191
990282006802	heme exporter protein CcmB; Region: ccmB; TIGR01190
990282006803	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
990282006804	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282006805	Walker A/P-loop; other site
990282006806	ATP binding site [chemical binding]; other site
990282006807	Q-loop/lid; other site
990282006808	ABC transporter signature motif; other site
990282006809	Walker B; other site
990282006810	D-loop; other site
990282006811	H-loop/switch region; other site
990282006812	cytochrome c-type protein NapC; Provisional; Region: PRK10617
990282006813	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
990282006814	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
990282006815	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
990282006816	4Fe-4S binding domain; Region: Fer4_5; pfam12801
990282006817	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
990282006818	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
990282006819	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
990282006820	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
990282006821	[4Fe-4S] binding site [ion binding]; other site
990282006822	molybdopterin cofactor binding site; other site
990282006823	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
990282006824	molybdopterin cofactor binding site; other site
990282006825	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
990282006826	ferredoxin-type protein; Provisional; Region: PRK10194
990282006827	4Fe-4S binding domain; Region: Fer4; cl02805
990282006828	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
990282006829	secondary substrate binding site; other site
990282006830	primary substrate binding site; other site
990282006831	inhibition loop; other site
990282006832	dimerization interface [polypeptide binding]; other site
990282006833	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
990282006834	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
990282006835	Walker A/P-loop; other site
990282006836	ATP binding site [chemical binding]; other site
990282006837	Q-loop/lid; other site
990282006838	ABC transporter signature motif; other site
990282006839	Walker B; other site
990282006840	D-loop; other site
990282006841	H-loop/switch region; other site
990282006842	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
990282006843	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
990282006844	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
990282006845	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282006846	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
990282006847	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
990282006848	DNA binding site [nucleotide binding]
990282006849	active site
990282006850	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
990282006851	ApbE family; Region: ApbE; pfam02424
990282006852	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
990282006853	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
990282006854	trimer interface [polypeptide binding]; other site
990282006855	eyelet of channel; other site
990282006856	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
990282006857	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282006858	ATP binding site [chemical binding]; other site
990282006859	G-X-G motif; other site
990282006860	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
990282006861	putative binding surface; other site
990282006862	active site
990282006863	transcriptional regulator RcsB; Provisional; Region: PRK10840
990282006864	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282006865	active site
990282006866	phosphorylation site [posttranslational modification]
990282006867	intermolecular recognition site; other site
990282006868	dimerization interface [polypeptide binding]; other site
990282006869	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282006870	DNA binding residues [nucleotide binding]
990282006871	dimerization interface [polypeptide binding]; other site
990282006872	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
990282006873	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282006874	dimer interface [polypeptide binding]; other site
990282006875	phosphorylation site [posttranslational modification]
990282006876	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282006877	ATP binding site [chemical binding]; other site
990282006878	Mg2+ binding site [ion binding]; other site
990282006879	G-X-G motif; other site
990282006880	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
990282006881	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282006882	active site
990282006883	phosphorylation site [posttranslational modification]
990282006884	intermolecular recognition site; other site
990282006885	dimerization interface [polypeptide binding]; other site
990282006886	DNA gyrase subunit A; Validated; Region: PRK05560
990282006887	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
990282006888	CAP-like domain; other site
990282006889	active site
990282006890	primary dimer interface [polypeptide binding]; other site
990282006891	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
990282006892	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
990282006893	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
990282006894	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
990282006895	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
990282006896	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
990282006897	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
990282006898	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
990282006899	active site pocket [active]
990282006900	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
990282006901	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282006902	putative substrate translocation pore; other site
990282006903	Transcriptional regulators [Transcription]; Region: GntR; COG1802
990282006904	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282006905	DNA-binding site [nucleotide binding]; DNA binding site
990282006906	FCD domain; Region: FCD; pfam07729
990282006907	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
990282006908	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282006909	S-adenosylmethionine binding site [chemical binding]; other site
990282006910	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
990282006911	ATP cone domain; Region: ATP-cone; pfam03477
990282006912	Class I ribonucleotide reductase; Region: RNR_I; cd01679
990282006913	active site
990282006914	dimer interface [polypeptide binding]; other site
990282006915	catalytic residues [active]
990282006916	effector binding site; other site
990282006917	R2 peptide binding site; other site
990282006918	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
990282006919	dimer interface [polypeptide binding]; other site
990282006920	putative radical transfer pathway; other site
990282006921	diiron center [ion binding]; other site
990282006922	tyrosyl radical; other site
990282006923	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
990282006924	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
990282006925	catalytic loop [active]
990282006926	iron binding site [ion binding]; other site
990282006927	Major Facilitator Superfamily; Region: MFS_1; pfam07690
990282006928	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282006929	putative substrate translocation pore; other site
990282006930	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
990282006931	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282006932	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
990282006933	dimerization interface [polypeptide binding]; other site
990282006934	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
990282006935	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
990282006936	active site
990282006937	catalytic site [active]
990282006938	metal binding site [ion binding]; metal-binding site
990282006939	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
990282006940	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282006941	putative substrate translocation pore; other site
990282006942	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
990282006943	hydroxyglutarate oxidase; Provisional; Region: PRK11728
990282006944	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
990282006945	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
990282006946	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
990282006947	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
990282006948	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
990282006949	Cysteine-rich domain; Region: CCG; pfam02754
990282006950	Cysteine-rich domain; Region: CCG; pfam02754
990282006951	deubiquitinase SseL; Provisional; Region: PRK14848
990282006952	hypothetical protein; Provisional; Region: PRK03673
990282006953	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
990282006954	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282006955	D-galactonate transporter; Region: 2A0114; TIGR00893
990282006956	putative substrate translocation pore; other site
990282006957	L-rhamnonate dehydratase; Provisional; Region: PRK15440
990282006958	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
990282006959	putative active site pocket [active]
990282006960	putative metal binding site [ion binding]; other site
990282006961	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
990282006962	Transcriptional regulator [Transcription]; Region: IclR; COG1414
990282006963	Bacterial transcriptional regulator; Region: IclR; pfam01614
990282006964	hypothetical protein; Provisional; Region: PRK03673
990282006965	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
990282006966	putative MPT binding site; other site
990282006967	Competence-damaged protein; Region: CinA; cl00666
990282006968	YfaZ precursor; Region: YfaZ; pfam07437
990282006969	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
990282006970	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
990282006971	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
990282006972	catalytic core [active]
990282006973	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
990282006974	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
990282006975	inhibitor-cofactor binding pocket; inhibition site
990282006976	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282006977	catalytic residue [active]
990282006978	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
990282006979	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
990282006980	Ligand binding site; other site
990282006981	Putative Catalytic site; other site
990282006982	DXD motif; other site
990282006983	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
990282006984	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
990282006985	active site
990282006986	substrate binding site [chemical binding]; other site
990282006987	cosubstrate binding site; other site
990282006988	catalytic site [active]
990282006989	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
990282006990	active site
990282006991	hexamer interface [polypeptide binding]; other site
990282006992	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
990282006993	NAD binding site [chemical binding]; other site
990282006994	substrate binding site [chemical binding]; other site
990282006995	active site
990282006996	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
990282006997	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
990282006998	putative active site [active]
990282006999	putative catalytic site [active]
990282007000	putative Zn binding site [ion binding]; other site
990282007001	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
990282007002	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
990282007003	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
990282007004	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
990282007005	signal transduction protein PmrD; Provisional; Region: PRK15450
990282007006	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
990282007007	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
990282007008	acyl-activating enzyme (AAE) consensus motif; other site
990282007009	putative AMP binding site [chemical binding]; other site
990282007010	putative active site [active]
990282007011	putative CoA binding site [chemical binding]; other site
990282007012	O-succinylbenzoate synthase [Coenzyme metabolism]; Region: MenC; COG1441
990282007013	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
990282007014	active site
990282007015	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
990282007016	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
990282007017	substrate binding site [chemical binding]; other site
990282007018	oxyanion hole (OAH) forming residues; other site
990282007019	trimer interface [polypeptide binding]; other site
990282007020	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
990282007021	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
990282007022	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
990282007023	dimer interface [polypeptide binding]; other site
990282007024	tetramer interface [polypeptide binding]; other site
990282007025	PYR/PP interface [polypeptide binding]; other site
990282007026	TPP binding site [chemical binding]; other site
990282007027	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
990282007028	TPP-binding site; other site
990282007029	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
990282007030	isochorismate synthases; Region: isochor_syn; TIGR00543
990282007031	hypothetical protein; Provisional; Region: PRK10404
990282007032	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282007033	Coenzyme A binding pocket [chemical binding]; other site
990282007034	ribonuclease BN; Region: true_RNase_BN; TIGR02649
990282007035	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
990282007036	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
990282007037	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282007038	active site
990282007039	phosphorylation site [posttranslational modification]
990282007040	intermolecular recognition site; other site
990282007041	dimerization interface [polypeptide binding]; other site
990282007042	von Willebrand factor; Region: vWF_A; pfam12450
990282007043	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
990282007044	VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subgroup; cd01465
990282007045	metal ion-dependent adhesion site (MIDAS); other site
990282007046	Domain of unknown function (DUF3520); Region: DUF3520; pfam12034
990282007047	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
990282007048	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
990282007049	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
990282007050	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
990282007051	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
990282007052	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
990282007053	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
990282007054	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
990282007055	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
990282007056	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
990282007057	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
990282007058	4Fe-4S binding domain; Region: Fer4; pfam00037
990282007059	4Fe-4S binding domain; Region: Fer4; pfam00037
990282007060	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
990282007061	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
990282007062	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
990282007063	catalytic loop [active]
990282007064	iron binding site [ion binding]; other site
990282007065	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
990282007066	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
990282007067	[4Fe-4S] binding site [ion binding]; other site
990282007068	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
990282007069	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
990282007070	SLBB domain; Region: SLBB; pfam10531
990282007071	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
990282007072	NADH dehydrogenase subunit E; Validated; Region: PRK07539
990282007073	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
990282007074	putative dimer interface [polypeptide binding]; other site
990282007075	[2Fe-2S] cluster binding site [ion binding]; other site
990282007076	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
990282007077	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
990282007078	NADH dehydrogenase subunit D; Validated; Region: PRK06075
990282007079	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
990282007080	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
990282007081	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
990282007082	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282007083	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
990282007084	putative dimerization interface [polypeptide binding]; other site
990282007085	aminotransferase AlaT; Validated; Region: PRK09265
990282007086	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
990282007087	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282007088	homodimer interface [polypeptide binding]; other site
990282007089	catalytic residue [active]
990282007090	5'-nucleotidase; Provisional; Region: PRK03826
990282007091	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
990282007092	transmembrane helices; other site
990282007093	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
990282007094	TrkA-C domain; Region: TrkA_C; pfam02080
990282007095	TrkA-C domain; Region: TrkA_C; pfam02080
990282007096	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
990282007097	putative phosphatase; Provisional; Region: PRK11587
990282007098	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282007099	motif II; other site
990282007100	hypothetical protein; Validated; Region: PRK05445
990282007101	hypothetical protein; Provisional; Region: PRK01816
990282007102	propionate/acetate kinase; Provisional; Region: PRK12379
990282007103	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
990282007104	phosphate acetyltransferase; Reviewed; Region: PRK05632
990282007105	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
990282007106	DRTGG domain; Region: DRTGG; pfam07085
990282007107	phosphate acetyltransferase; Region: pta; TIGR00651
990282007108	hypothetical protein; Provisional; Region: PRK11588
990282007109	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
990282007110	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
990282007111	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
990282007112	PYR/PP interface [polypeptide binding]; other site
990282007113	dimer interface [polypeptide binding]; other site
990282007114	TPP binding site [chemical binding]; other site
990282007115	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
990282007116	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
990282007117	TPP-binding site [chemical binding]; other site
990282007118	dimer interface [polypeptide binding]; other site
990282007119	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK12996
990282007120	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
990282007121	active site
990282007122	P-loop; other site
990282007123	phosphorylation site [posttranslational modification]
990282007124	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
990282007125	active site
990282007126	phosphorylation site [posttranslational modification]
990282007127	Transcriptional regulators [Transcription]; Region: PurR; COG1609
990282007128	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
990282007129	DNA binding site [nucleotide binding]
990282007130	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
990282007131	putative dimerization interface [polypeptide binding]; other site
990282007132	putative ligand binding site [chemical binding]; other site
990282007133	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
990282007134	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
990282007135	nudix motif; other site
990282007136	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
990282007137	active site
990282007138	metal binding site [ion binding]; metal-binding site
990282007139	homotetramer interface [polypeptide binding]; other site
990282007140	glutathione S-transferase; Provisional; Region: PRK15113
990282007141	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
990282007142	C-terminal domain interface [polypeptide binding]; other site
990282007143	GSH binding site (G-site) [chemical binding]; other site
990282007144	dimer interface [polypeptide binding]; other site
990282007145	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
990282007146	N-terminal domain interface [polypeptide binding]; other site
990282007147	putative dimer interface [polypeptide binding]; other site
990282007148	putative substrate binding pocket (H-site) [chemical binding]; other site
990282007149	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
990282007150	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
990282007151	C-terminal domain interface [polypeptide binding]; other site
990282007152	GSH binding site (G-site) [chemical binding]; other site
990282007153	dimer interface [polypeptide binding]; other site
990282007154	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
990282007155	N-terminal domain interface [polypeptide binding]; other site
990282007156	putative dimer interface [polypeptide binding]; other site
990282007157	active site
990282007158	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
990282007159	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
990282007160	putative NAD(P) binding site [chemical binding]; other site
990282007161	putative active site [active]
990282007162	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
990282007163	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
990282007164	Walker A/P-loop; other site
990282007165	ATP binding site [chemical binding]; other site
990282007166	Q-loop/lid; other site
990282007167	ABC transporter signature motif; other site
990282007168	Walker B; other site
990282007169	D-loop; other site
990282007170	H-loop/switch region; other site
990282007171	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
990282007172	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282007173	dimer interface [polypeptide binding]; other site
990282007174	conserved gate region; other site
990282007175	putative PBP binding loops; other site
990282007176	ABC-ATPase subunit interface; other site
990282007177	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
990282007178	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282007179	dimer interface [polypeptide binding]; other site
990282007180	conserved gate region; other site
990282007181	putative PBP binding loops; other site
990282007182	ABC-ATPase subunit interface; other site
990282007183	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
990282007184	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
990282007185	substrate binding pocket [chemical binding]; other site
990282007186	membrane-bound complex binding site; other site
990282007187	hinge residues; other site
990282007188	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
990282007189	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
990282007190	substrate binding pocket [chemical binding]; other site
990282007191	membrane-bound complex binding site; other site
990282007192	hinge residues; other site
990282007193	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
990282007194	Flavoprotein; Region: Flavoprotein; pfam02441
990282007195	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
990282007196	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
990282007197	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815
990282007198	dimer interface [polypeptide binding]; other site
990282007199	active site
990282007200	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
990282007201	substrate binding site [chemical binding]; other site
990282007202	catalytic residue [active]
990282007203	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
990282007204	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
990282007205	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
990282007206	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
990282007207	catalytic residue [active]
990282007208	PAS fold; Region: PAS_4; pfam08448
990282007209	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
990282007210	putative active site [active]
990282007211	heme pocket [chemical binding]; other site
990282007212	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
990282007213	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282007214	Walker A motif; other site
990282007215	ATP binding site [chemical binding]; other site
990282007216	Walker B motif; other site
990282007217	arginine finger; other site
990282007218	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
990282007219	amidophosphoribosyltransferase; Provisional; Region: PRK09246
990282007220	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
990282007221	active site
990282007222	tetramer interface [polypeptide binding]; other site
990282007223	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
990282007224	active site
990282007225	colicin V production protein; Provisional; Region: PRK10845
990282007226	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
990282007227	cell division protein DedD; Provisional; Region: PRK11633
990282007228	Sporulation related domain; Region: SPOR; pfam05036
990282007229	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
990282007230	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
990282007231	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
990282007232	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
990282007233	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
990282007234	hypothetical protein; Provisional; Region: PRK10847
990282007235	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
990282007236	Pseudouridylate synthase [Translation, ribosomal structure and biogenesis]; Region: TruA; COG0101
990282007237	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
990282007238	dimerization interface 3.5A [polypeptide binding]; other site
990282007239	active site
990282007240	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
990282007241	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
990282007242	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
990282007243	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
990282007244	ligand binding site [chemical binding]; other site
990282007245	NAD binding site [chemical binding]; other site
990282007246	catalytic site [active]
990282007247	homodimer interface [polypeptide binding]; other site
990282007248	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
990282007249	putative transporter; Provisional; Region: PRK12382
990282007250	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282007251	putative substrate translocation pore; other site
990282007252	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
990282007253	non-specific DNA binding site [nucleotide binding]; other site
990282007254	salt bridge; other site
990282007255	sequence-specific DNA binding site [nucleotide binding]; other site
990282007256	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
990282007257	CAAX protease self-immunity; Region: Abi; pfam02517
990282007258	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
990282007259	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
990282007260	dimer interface [polypeptide binding]; other site
990282007261	active site
990282007262	Uncharacterized conserved protein [Function unknown]; Region: COG4121
990282007263	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
990282007264	YfcL protein; Region: YfcL; pfam08891
990282007265	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
990282007266	hypothetical protein; Provisional; Region: PRK10621
990282007267	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
990282007268	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
990282007269	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
990282007270	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
990282007271	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
990282007272	Tetramer interface [polypeptide binding]; other site
990282007273	active site
990282007274	FMN-binding site [chemical binding]; other site
990282007275	HemK family putative methylases; Region: hemK_fam; TIGR00536
990282007276	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282007277	S-adenosylmethionine binding site [chemical binding]; other site
990282007278	hypothetical protein; Provisional; Region: PRK04946
990282007279	Smr domain; Region: Smr; pfam01713
990282007280	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
990282007281	catalytic core [active]
990282007282	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
990282007283	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
990282007284	substrate binding site [chemical binding]; other site
990282007285	oxyanion hole (OAH) forming residues; other site
990282007286	trimer interface [polypeptide binding]; other site
990282007287	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
990282007288	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
990282007289	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
990282007290	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
990282007291	dimer interface [polypeptide binding]; other site
990282007292	active site
990282007293	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
990282007294	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
990282007295	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
990282007296	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
990282007297	outer membrane protease; Reviewed; Region: PRK10993
990282007298	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
990282007299	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282007300	active site
990282007301	phosphorylation site [posttranslational modification]
990282007302	intermolecular recognition site; other site
990282007303	dimerization interface [polypeptide binding]; other site
990282007304	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
990282007305	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
990282007306	Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms]; Region: COG4192
990282007307	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
990282007308	dimerization interface [polypeptide binding]; other site
990282007309	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282007310	dimer interface [polypeptide binding]; other site
990282007311	phosphorylation site [posttranslational modification]
990282007312	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282007313	ATP binding site [chemical binding]; other site
990282007314	Mg2+ binding site [ion binding]; other site
990282007315	G-X-G motif; other site
990282007316	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
990282007317	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
990282007318	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
990282007319	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282007320	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282007321	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
990282007322	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
990282007323	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
990282007324	putative acyl-acceptor binding pocket; other site
990282007325	aminotransferase; Validated; Region: PRK08175
990282007326	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
990282007327	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282007328	homodimer interface [polypeptide binding]; other site
990282007329	catalytic residue [active]
990282007330	glucokinase; Provisional; Region: glk; PRK00292
990282007331	glucokinase, proteobacterial type; Region: glk; TIGR00749
990282007332	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
990282007333	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
990282007334	Cl- selectivity filter; other site
990282007335	Cl- binding residues [ion binding]; other site
990282007336	pore gating glutamate residue; other site
990282007337	dimer interface [polypeptide binding]; other site
990282007338	indolepyruvate decarboxylase, Erwinia family; Region: indolpyr_decarb; TIGR03393
990282007339	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
990282007340	dimer interface [polypeptide binding]; other site
990282007341	PYR/PP interface [polypeptide binding]; other site
990282007342	TPP binding site [chemical binding]; other site
990282007343	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
990282007344	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
990282007345	TPP-binding site [chemical binding]; other site
990282007346	dimer interface [polypeptide binding]; other site
990282007347	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
990282007348	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
990282007349	active site
990282007350	catalytic tetrad [active]
990282007351	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
990282007352	manganese transport protein MntH; Reviewed; Region: PRK00701
990282007353	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
990282007354	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
990282007355	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
990282007356	Nucleoside recognition; Region: Gate; pfam07670
990282007357	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
990282007358	MASE1; Region: MASE1; pfam05231
990282007359	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
990282007360	diguanylate cyclase; Region: GGDEF; smart00267
990282007361	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
990282007362	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
990282007363	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
990282007364	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
990282007365	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
990282007366	active site
990282007367	HIGH motif; other site
990282007368	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
990282007369	active site
990282007370	KMSKS motif; other site
990282007371	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
990282007372	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282007373	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
990282007374	putative dimerization interface [polypeptide binding]; other site
990282007375	putative substrate binding pocket [chemical binding]; other site
990282007376	XapX domain; Region: XapX; TIGR03510
990282007377	nucleoside transporter; Region: 2A0110; TIGR00889
990282007378	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282007379	putative substrate translocation pore; other site
990282007380	purine nucleoside phosphorylase; Provisional; Region: PRK08202
990282007381	hypothetical protein; Provisional; Region: PRK11528
990282007382	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282007383	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282007384	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
990282007385	putative dimerization interface [polypeptide binding]; other site
990282007386	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
990282007387	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
990282007388	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
990282007389	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
990282007390	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
990282007391	nucleotide binding pocket [chemical binding]; other site
990282007392	K-X-D-G motif; other site
990282007393	catalytic site [active]
990282007394	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
990282007395	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
990282007396	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
990282007397	Dimer interface [polypeptide binding]; other site
990282007398	BRCT sequence motif; other site
990282007399	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
990282007400	cell division protein ZipA; Provisional; Region: PRK03427
990282007401	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
990282007402	FtsZ protein binding site [polypeptide binding]; other site
990282007403	putative sulfate transport protein CysZ; Validated; Region: PRK04949
990282007404	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
990282007405	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
990282007406	dimer interface [polypeptide binding]; other site
990282007407	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282007408	catalytic residue [active]
990282007409	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
990282007410	dimerization domain swap beta strand [polypeptide binding]; other site
990282007411	regulatory protein interface [polypeptide binding]; other site
990282007412	active site
990282007413	regulatory phosphorylation site [posttranslational modification]; other site
990282007414	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
990282007415	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
990282007416	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
990282007417	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
990282007418	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
990282007419	HPr interaction site; other site
990282007420	glycerol kinase (GK) interaction site [polypeptide binding]; other site
990282007421	active site
990282007422	phosphorylation site [posttranslational modification]
990282007423	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
990282007424	dimer interface [polypeptide binding]; other site
990282007425	pyridoxamine kinase; Validated; Region: PRK05756
990282007426	pyridoxal binding site [chemical binding]; other site
990282007427	ATP binding site [chemical binding]; other site
990282007428	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
990282007429	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282007430	DNA-binding site [nucleotide binding]; DNA binding site
990282007431	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
990282007432	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282007433	homodimer interface [polypeptide binding]; other site
990282007434	catalytic residue [active]
990282007435	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
990282007436	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
990282007437	catalytic triad [active]
990282007438	hypothetical protein; Provisional; Region: PRK10318
990282007439	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
990282007440	Transglycosylase; Region: Transgly; cl17702
990282007441	cysteine synthase B; Region: cysM; TIGR01138
990282007442	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
990282007443	dimer interface [polypeptide binding]; other site
990282007444	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282007445	catalytic residue [active]
990282007446	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
990282007447	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
990282007448	Walker A/P-loop; other site
990282007449	ATP binding site [chemical binding]; other site
990282007450	Q-loop/lid; other site
990282007451	ABC transporter signature motif; other site
990282007452	Walker B; other site
990282007453	D-loop; other site
990282007454	H-loop/switch region; other site
990282007455	TOBE-like domain; Region: TOBE_3; pfam12857
990282007456	sulfate transport protein; Provisional; Region: cysT; CHL00187
990282007457	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282007458	dimer interface [polypeptide binding]; other site
990282007459	conserved gate region; other site
990282007460	putative PBP binding loops; other site
990282007461	ABC-ATPase subunit interface; other site
990282007462	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
990282007463	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282007464	dimer interface [polypeptide binding]; other site
990282007465	conserved gate region; other site
990282007466	putative PBP binding loops; other site
990282007467	ABC-ATPase subunit interface; other site
990282007468	thiosulfate transporter subunit; Provisional; Region: PRK10852
990282007469	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
990282007470	short chain dehydrogenase; Provisional; Region: PRK08226
990282007471	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
990282007472	NAD binding site [chemical binding]; other site
990282007473	homotetramer interface [polypeptide binding]; other site
990282007474	homodimer interface [polypeptide binding]; other site
990282007475	active site
990282007476	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
990282007477	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
990282007478	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
990282007479	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
990282007480	putative acetyltransferase; Provisional; Region: PRK03624
990282007481	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282007482	Coenzyme A binding pocket [chemical binding]; other site
990282007483	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
990282007484	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
990282007485	active site
990282007486	metal binding site [ion binding]; metal-binding site
990282007487	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
990282007488	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
990282007489	transcriptional regulator EutR; Provisional; Region: PRK10130
990282007490	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282007491	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282007492	carboxysome structural protein EutK; Provisional; Region: PRK15466
990282007493	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
990282007494	Hexamer interface [polypeptide binding]; other site
990282007495	Hexagonal pore residue; other site
990282007496	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
990282007497	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
990282007498	putative hexamer interface [polypeptide binding]; other site
990282007499	putative hexagonal pore; other site
990282007500	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
990282007501	putative hexamer interface [polypeptide binding]; other site
990282007502	putative hexagonal pore; other site
990282007503	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
990282007504	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
990282007505	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
990282007506	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
990282007507	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
990282007508	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
990282007509	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
990282007510	active site
990282007511	metal binding site [ion binding]; metal-binding site
990282007512	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
990282007513	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
990282007514	nucleotide binding site [chemical binding]; other site
990282007515	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
990282007516	putative catalytic cysteine [active]
990282007517	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
990282007518	Hexamer/Pentamer interface [polypeptide binding]; other site
990282007519	central pore; other site
990282007520	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
990282007521	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
990282007522	Hexamer interface [polypeptide binding]; other site
990282007523	Putative hexagonal pore residue; other site
990282007524	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
990282007525	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
990282007526	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
990282007527	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
990282007528	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
990282007529	G1 box; other site
990282007530	GTP/Mg2+ binding site [chemical binding]; other site
990282007531	G2 box; other site
990282007532	Switch I region; other site
990282007533	G3 box; other site
990282007534	Switch II region; other site
990282007535	G4 box; other site
990282007536	G5 box; other site
990282007537	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
990282007538	putative hexamer interface [polypeptide binding]; other site
990282007539	putative hexagonal pore; other site
990282007540	Transposase IS200 like; Region: Y1_Tnp; pfam01797
990282007541	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
990282007542	Malic enzyme, N-terminal domain; Region: malic; pfam00390
990282007543	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
990282007544	putative NAD(P) binding site [chemical binding]; other site
990282007545	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
990282007546	transaldolase-like protein; Provisional; Region: PTZ00411
990282007547	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
990282007548	active site
990282007549	dimer interface [polypeptide binding]; other site
990282007550	catalytic residue [active]
990282007551	transketolase; Reviewed; Region: PRK12753
990282007552	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
990282007553	TPP-binding site [chemical binding]; other site
990282007554	dimer interface [polypeptide binding]; other site
990282007555	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
990282007556	PYR/PP interface [polypeptide binding]; other site
990282007557	dimer interface [polypeptide binding]; other site
990282007558	TPP binding site [chemical binding]; other site
990282007559	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
990282007560	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
990282007561	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
990282007562	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
990282007563	dimer interface [polypeptide binding]; other site
990282007564	ADP-ribose binding site [chemical binding]; other site
990282007565	active site
990282007566	nudix motif; other site
990282007567	metal binding site [ion binding]; metal-binding site
990282007568	putative periplasmic esterase; Provisional; Region: PRK03642
990282007569	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
990282007570	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
990282007571	4Fe-4S binding domain; Region: Fer4; pfam00037
990282007572	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
990282007573	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
990282007574	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
990282007575	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
990282007576	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
990282007577	dimerization interface [polypeptide binding]; other site
990282007578	Histidine kinase; Region: HisKA_3; pfam07730
990282007579	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282007580	ATP binding site [chemical binding]; other site
990282007581	Mg2+ binding site [ion binding]; other site
990282007582	G-X-G motif; other site
990282007583	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
990282007584	Protein export membrane protein; Region: SecD_SecF; cl14618
990282007585	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
990282007586	ArsC family; Region: ArsC; pfam03960
990282007587	putative catalytic residues [active]
990282007588	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
990282007589	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
990282007590	metal binding site [ion binding]; metal-binding site
990282007591	dimer interface [polypeptide binding]; other site
990282007592	hypothetical protein; Provisional; Region: PRK13664
990282007593	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
990282007594	Helicase; Region: Helicase_RecD; pfam05127
990282007595	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
990282007596	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
990282007597	Predicted metalloprotease [General function prediction only]; Region: COG2321
990282007598	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
990282007599	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
990282007600	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
990282007601	ATP binding site [chemical binding]; other site
990282007602	active site
990282007603	substrate binding site [chemical binding]; other site
990282007604	lipoprotein; Provisional; Region: PRK11679
990282007605	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
990282007606	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
990282007607	dihydrodipicolinate synthase; Region: dapA; TIGR00674
990282007608	dimer interface [polypeptide binding]; other site
990282007609	active site
990282007610	catalytic residue [active]
990282007611	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
990282007612	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
990282007613	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
990282007614	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
990282007615	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
990282007616	catalytic triad [active]
990282007617	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
990282007618	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
990282007619	Domain of unknown function DUF20; Region: UPF0118; pfam01594
990282007620	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
990282007621	Peptidase family M48; Region: Peptidase_M48; cl12018
990282007622	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
990282007623	ArsC family; Region: ArsC; pfam03960
990282007624	catalytic residues [active]
990282007625	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
990282007626	DNA replication initiation factor; Provisional; Region: PRK08084
990282007627	uracil transporter; Provisional; Region: PRK10720
990282007628	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
990282007629	active site
990282007630	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
990282007631	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
990282007632	dimerization interface [polypeptide binding]; other site
990282007633	putative ATP binding site [chemical binding]; other site
990282007634	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
990282007635	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
990282007636	active site
990282007637	substrate binding site [chemical binding]; other site
990282007638	cosubstrate binding site; other site
990282007639	catalytic site [active]
990282007640	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
990282007641	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
990282007642	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
990282007643	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
990282007644	putative active site [active]
990282007645	catalytic site [active]
990282007646	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
990282007647	domain interface [polypeptide binding]; other site
990282007648	active site
990282007649	catalytic site [active]
990282007650	exopolyphosphatase; Provisional; Region: PRK10854
990282007651	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
990282007652	nucleotide binding site [chemical binding]; other site
990282007653	MASE1; Region: MASE1; pfam05231
990282007654	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
990282007655	diguanylate cyclase; Region: GGDEF; smart00267
990282007656	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
990282007657	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
990282007658	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
990282007659	Integrase core domain; Region: rve; pfam00665
990282007660	GMP synthase; Reviewed; Region: guaA; PRK00074
990282007661	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
990282007662	AMP/PPi binding site [chemical binding]; other site
990282007663	candidate oxyanion hole; other site
990282007664	catalytic triad [active]
990282007665	potential glutamine specificity residues [chemical binding]; other site
990282007666	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
990282007667	ATP Binding subdomain [chemical binding]; other site
990282007668	Ligand Binding sites [chemical binding]; other site
990282007669	Dimerization subdomain; other site
990282007670	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
990282007671	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
990282007672	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
990282007673	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
990282007674	active site
990282007675	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
990282007676	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
990282007677	generic binding surface II; other site
990282007678	generic binding surface I; other site
990282007679	AIDA autotransporter-like protein ShdA; Provisional; Region: PRK15319
990282007680	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
990282007681	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
990282007682	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
990282007683	Autotransporter beta-domain; Region: Autotransporter; smart00869
990282007684	outer membrane protein RatA; Provisional; Region: PRK15315
990282007685	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
990282007686	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
990282007687	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
990282007688	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
990282007689	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
990282007690	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
990282007691	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
990282007692	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
990282007693	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
990282007694	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
990282007695	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
990282007696	intimin-like protein SinH; Provisional; Region: PRK15318
990282007697	intimin-like protein SinH; Provisional; Region: PRK15318
990282007698	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
990282007699	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
990282007700	GTP-binding protein Der; Reviewed; Region: PRK00093
990282007701	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
990282007702	G1 box; other site
990282007703	GTP/Mg2+ binding site [chemical binding]; other site
990282007704	Switch I region; other site
990282007705	G2 box; other site
990282007706	Switch II region; other site
990282007707	G3 box; other site
990282007708	G4 box; other site
990282007709	G5 box; other site
990282007710	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
990282007711	G1 box; other site
990282007712	GTP/Mg2+ binding site [chemical binding]; other site
990282007713	Switch I region; other site
990282007714	G2 box; other site
990282007715	G3 box; other site
990282007716	Switch II region; other site
990282007717	G4 box; other site
990282007718	G5 box; other site
990282007719	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
990282007720	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
990282007721	Trp docking motif [polypeptide binding]; other site
990282007722	active site
990282007723	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
990282007724	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
990282007725	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
990282007726	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
990282007727	dimer interface [polypeptide binding]; other site
990282007728	motif 1; other site
990282007729	active site
990282007730	motif 2; other site
990282007731	motif 3; other site
990282007732	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
990282007733	anticodon binding site; other site
990282007734	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
990282007735	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
990282007736	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
990282007737	cytoskeletal protein RodZ; Provisional; Region: PRK10856
990282007738	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
990282007739	non-specific DNA binding site [nucleotide binding]; other site
990282007740	salt bridge; other site
990282007741	sequence-specific DNA binding site [nucleotide binding]; other site
990282007742	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
990282007743	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
990282007744	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282007745	FeS/SAM binding site; other site
990282007746	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
990282007747	active site
990282007748	multimer interface [polypeptide binding]; other site
990282007749	4Fe-4S binding domain; Region: Fer4; pfam00037
990282007750	hydrogenase 4 subunit H; Validated; Region: PRK08222
990282007751	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
990282007752	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
990282007753	4Fe-4S binding domain; Region: Fer4; pfam00037
990282007754	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
990282007755	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
990282007756	putative [Fe4-S4] binding site [ion binding]; other site
990282007757	putative molybdopterin cofactor binding site [chemical binding]; other site
990282007758	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
990282007759	putative molybdopterin cofactor binding site; other site
990282007760	penicillin-binding protein 1C; Provisional; Region: PRK11240
990282007761	Transglycosylase; Region: Transgly; pfam00912
990282007762	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
990282007763	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
990282007764	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
990282007765	MG2 domain; Region: A2M_N; pfam01835
990282007766	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
990282007767	surface patch; other site
990282007768	thioester region; other site
990282007769	specificity defining residues; other site
990282007770	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
990282007771	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
990282007772	active site residue [active]
990282007773	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
990282007774	active site residue [active]
990282007775	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
990282007776	aminopeptidase B; Provisional; Region: PRK05015
990282007777	Peptidase; Region: DUF3663; pfam12404
990282007778	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
990282007779	interface (dimer of trimers) [polypeptide binding]; other site
990282007780	Substrate-binding/catalytic site; other site
990282007781	Zn-binding sites [ion binding]; other site
990282007782	hypothetical protein; Provisional; Region: PRK10721
990282007783	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
990282007784	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
990282007785	catalytic loop [active]
990282007786	iron binding site [ion binding]; other site
990282007787	chaperone protein HscA; Provisional; Region: hscA; PRK05183
990282007788	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
990282007789	nucleotide binding site [chemical binding]; other site
990282007790	putative NEF/HSP70 interaction site [polypeptide binding]; other site
990282007791	SBD interface [polypeptide binding]; other site
990282007792	co-chaperone HscB; Provisional; Region: hscB; PRK05014
990282007793	DnaJ domain; Region: DnaJ; pfam00226
990282007794	HSP70 interaction site [polypeptide binding]; other site
990282007795	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
990282007796	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
990282007797	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
990282007798	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
990282007799	trimerization site [polypeptide binding]; other site
990282007800	active site
990282007801	cysteine desulfurase; Provisional; Region: PRK14012
990282007802	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
990282007803	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
990282007804	catalytic residue [active]
990282007805	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
990282007806	Rrf2 family protein; Region: rrf2_super; TIGR00738
990282007807	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
990282007808	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
990282007809	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
990282007810	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
990282007811	active site
990282007812	dimerization interface [polypeptide binding]; other site
990282007813	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
990282007814	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
990282007815	sulfite reductase, subunit A; Region: sulfite_red_A; TIGR02910
990282007816	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
990282007817	anaerobic sulfite reductase subunit B; Provisional; Region: PRK08221
990282007818	Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is...; Region: sulfite_reductase_like; cd06221
990282007819	FAD binding pocket [chemical binding]; other site
990282007820	FAD binding motif [chemical binding]; other site
990282007821	phosphate binding motif [ion binding]; other site
990282007822	beta-alpha-beta structure motif; other site
990282007823	NAD binding pocket [chemical binding]; other site
990282007824	Iron coordination center [ion binding]; other site
990282007825	sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912
990282007826	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
990282007827	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
990282007828	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
990282007829	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
990282007830	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
990282007831	PRD domain; Region: PRD; pfam00874
990282007832	PRD domain; Region: PRD; pfam00874
990282007833	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
990282007834	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282007835	putative substrate translocation pore; other site
990282007836	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
990282007837	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
990282007838	dimer interface [polypeptide binding]; other site
990282007839	active site
990282007840	glycine-pyridoxal phosphate binding site [chemical binding]; other site
990282007841	folate binding site [chemical binding]; other site
990282007842	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
990282007843	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
990282007844	heme-binding site [chemical binding]; other site
990282007845	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
990282007846	FAD binding pocket [chemical binding]; other site
990282007847	FAD binding motif [chemical binding]; other site
990282007848	phosphate binding motif [ion binding]; other site
990282007849	beta-alpha-beta structure motif; other site
990282007850	NAD binding pocket [chemical binding]; other site
990282007851	Heme binding  pocket [chemical binding]; other site
990282007852	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
990282007853	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
990282007854	DNA binding site [nucleotide binding]
990282007855	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
990282007856	lysine decarboxylase CadA; Provisional; Region: PRK15400
990282007857	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
990282007858	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
990282007859	homodimer interface [polypeptide binding]; other site
990282007860	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282007861	catalytic residue [active]
990282007862	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
990282007863	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
990282007864	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282007865	putative substrate translocation pore; other site
990282007866	POT family; Region: PTR2; pfam00854
990282007867	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
990282007868	Nitrogen regulatory protein P-II; Region: P-II; smart00938
990282007869	response regulator GlrR; Provisional; Region: PRK15115
990282007870	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282007871	active site
990282007872	phosphorylation site [posttranslational modification]
990282007873	intermolecular recognition site; other site
990282007874	dimerization interface [polypeptide binding]; other site
990282007875	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282007876	Walker A motif; other site
990282007877	ATP binding site [chemical binding]; other site
990282007878	Walker B motif; other site
990282007879	arginine finger; other site
990282007880	hypothetical protein; Provisional; Region: PRK10722
990282007881	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
990282007882	HAMP domain; Region: HAMP; pfam00672
990282007883	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282007884	dimer interface [polypeptide binding]; other site
990282007885	phosphorylation site [posttranslational modification]
990282007886	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282007887	ATP binding site [chemical binding]; other site
990282007888	Mg2+ binding site [ion binding]; other site
990282007889	G-X-G motif; other site
990282007890	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
990282007891	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
990282007892	dimerization interface [polypeptide binding]; other site
990282007893	ATP binding site [chemical binding]; other site
990282007894	Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of...; Region: PurL; cd02193
990282007895	dimerization interface [polypeptide binding]; other site
990282007896	ATP binding site [chemical binding]; other site
990282007897	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
990282007898	putative active site [active]
990282007899	catalytic triad [active]
990282007900	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
990282007901	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
990282007902	substrate binding pocket [chemical binding]; other site
990282007903	membrane-bound complex binding site; other site
990282007904	hinge residues; other site
990282007905	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
990282007906	N-acetyl-D-glucosamine binding site [chemical binding]; other site
990282007907	catalytic residue [active]
990282007908	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
990282007909	nucleoside/Zn binding site; other site
990282007910	dimer interface [polypeptide binding]; other site
990282007911	catalytic motif [active]
990282007912	hypothetical protein; Provisional; Region: PRK11590
990282007913	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
990282007914	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
990282007915	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
990282007916	active site turn [active]
990282007917	phosphorylation site [posttranslational modification]
990282007918	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
990282007919	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
990282007920	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
990282007921	putative active site [active]
990282007922	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
990282007923	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
990282007924	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
990282007925	putative active site [active]
990282007926	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
990282007927	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
990282007928	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
990282007929	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
990282007930	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282007931	putative substrate translocation pore; other site
990282007932	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282007933	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282007934	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
990282007935	dimerization interface [polypeptide binding]; other site
990282007936	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
990282007937	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
990282007938	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
990282007939	active site
990282007940	hydrophilic channel; other site
990282007941	dimerization interface [polypeptide binding]; other site
990282007942	catalytic residues [active]
990282007943	active site lid [active]
990282007944	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
990282007945	Recombination protein O N terminal; Region: RecO_N; pfam11967
990282007946	Recombination protein O C terminal; Region: RecO_C; pfam02565
990282007947	GTPase Era; Reviewed; Region: era; PRK00089
990282007948	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
990282007949	G1 box; other site
990282007950	GTP/Mg2+ binding site [chemical binding]; other site
990282007951	Switch I region; other site
990282007952	G2 box; other site
990282007953	Switch II region; other site
990282007954	G3 box; other site
990282007955	G4 box; other site
990282007956	G5 box; other site
990282007957	KH domain; Region: KH_2; pfam07650
990282007958	ribonuclease III; Reviewed; Region: rnc; PRK00102
990282007959	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
990282007960	dimerization interface [polypeptide binding]; other site
990282007961	active site
990282007962	metal binding site [ion binding]; metal-binding site
990282007963	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
990282007964	dsRNA binding site [nucleotide binding]; other site
990282007965	signal peptidase I; Provisional; Region: PRK10861
990282007966	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
990282007967	Catalytic site [active]
990282007968	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
990282007969	GTP-binding protein LepA; Provisional; Region: PRK05433
990282007970	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
990282007971	G1 box; other site
990282007972	putative GEF interaction site [polypeptide binding]; other site
990282007973	GTP/Mg2+ binding site [chemical binding]; other site
990282007974	Switch I region; other site
990282007975	G2 box; other site
990282007976	G3 box; other site
990282007977	Switch II region; other site
990282007978	G4 box; other site
990282007979	G5 box; other site
990282007980	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
990282007981	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
990282007982	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
990282007983	type III secretion protein GogB; Provisional; Region: PRK15386
990282007984	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
990282007985	Macro domain, Appr-1"-pase family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose...; Region: Macro_Appr_pase; cd02900
990282007986	ADP-ribose binding site [chemical binding]; other site
990282007987	putative active site [active]
990282007988	dimer interface [polypeptide binding]; other site
990282007989	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
990282007990	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
990282007991	Phage Tail Collar Domain; Region: Collar; pfam07484
990282007992	Phage-related protein, tail component [Function unknown]; Region: COG4733
990282007993	Putative phage tail protein; Region: Phage-tail_3; pfam13550
990282007994	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
990282007995	Interdomain contacts; other site
990282007996	Cytokine receptor motif; other site
990282007997	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
990282007998	Fibronectin type III protein; Region: DUF3672; pfam12421
990282007999	Phage-related protein, tail component [Function unknown]; Region: COG4723
990282008000	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
990282008001	MPN+ (JAMM) motif; other site
990282008002	Zinc-binding site [ion binding]; other site
990282008003	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
990282008004	NlpC/P60 family; Region: NLPC_P60; cl17555
990282008005	Phage-related protein [Function unknown]; Region: gp18; COG4672
990282008006	Phage-related protein [Function unknown]; Region: COG4718
990282008007	Phage-related minor tail protein [Function unknown]; Region: COG5281
990282008008	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
990282008009	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
990282008010	Minor tail protein T; Region: Phage_tail_T; pfam06223
990282008011	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
990282008012	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
990282008013	Phage tail protein; Region: Phage_tail_3; pfam08813
990282008014	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
990282008015	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
990282008016	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
990282008017	Probable transposase; Region: OrfB_IS605; pfam01385
990282008018	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
990282008019	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
990282008020	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; cl05094
990282008021	DNA packaging protein FI; Region: Packaging_FI; pfam14000
990282008022	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
990282008023	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
990282008024	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
990282008025	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
990282008026	tandem repeat interface [polypeptide binding]; other site
990282008027	oligomer interface [polypeptide binding]; other site
990282008028	active site residues [active]
990282008029	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
990282008030	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
990282008031	gpW; Region: gpW; pfam02831
990282008032	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
990282008033	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
990282008034	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
990282008035	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
990282008036	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
990282008037	catalytic residues [active]
990282008038	phage holin, lambda family; Region: holin_lambda; TIGR01594
990282008039	PipA protein; Region: PipA; pfam07108
990282008040	ORF6N domain; Region: ORF6N; pfam10543
990282008041	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
990282008042	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
990282008043	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
990282008044	DinI-like family; Region: DinI; pfam06183
990282008045	NFkB-p65-degrading zinc protease; Region: Peptidase_M85; pfam13678
990282008046	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
990282008047	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
990282008048	putative replication protein; Provisional; Region: PRK12377
990282008049	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282008050	Walker A motif; other site
990282008051	ATP binding site [chemical binding]; other site
990282008052	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
990282008053	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
990282008054	primosomal protein DnaI; Provisional; Region: PRK02854
990282008055	Bacteriophage CII protein; Region: Phage_CII; pfam05269
990282008056	transcriptional repressor DicA; Reviewed; Region: PRK09706
990282008057	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
990282008058	non-specific DNA binding site [nucleotide binding]; other site
990282008059	sequence-specific DNA binding site [nucleotide binding]; other site
990282008060	salt bridge; other site
990282008061	AAA domain; Region: AAA_31; pfam13614
990282008062	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
990282008063	P-loop; other site
990282008064	Magnesium ion binding site [ion binding]; other site
990282008065	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
990282008066	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
990282008067	exonuclease VIII; Reviewed; Region: PRK09709
990282008068	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
990282008069	RecT family; Region: RecT; pfam03837
990282008070	Protein of unknown function (DUF4060); Region: DUF4060; pfam13269
990282008071	integrase; Provisional; Region: PRK09692
990282008072	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
990282008073	active site
990282008074	Int/Topo IB signature motif; other site
990282008075	SoxR reducing system protein RseC; Provisional; Region: PRK10862
990282008076	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
990282008077	anti-sigma E factor; Provisional; Region: rseB; PRK09455
990282008078	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
990282008079	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
990282008080	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
990282008081	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
990282008082	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
990282008083	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
990282008084	DNA binding residues [nucleotide binding]
990282008085	L-aspartate oxidase; Provisional; Region: PRK09077
990282008086	L-aspartate oxidase; Provisional; Region: PRK06175
990282008087	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
990282008088	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
990282008089	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282008090	S-adenosylmethionine binding site [chemical binding]; other site
990282008091	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
990282008092	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
990282008093	ATP binding site [chemical binding]; other site
990282008094	Mg++ binding site [ion binding]; other site
990282008095	motif III; other site
990282008096	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
990282008097	nucleotide binding region [chemical binding]; other site
990282008098	ATP-binding site [chemical binding]; other site
990282008099	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282008100	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282008101	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
990282008102	dimerization interface [polypeptide binding]; other site
990282008103	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
990282008104	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
990282008105	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
990282008106	ligand binding site [chemical binding]; other site
990282008107	active site
990282008108	UGI interface [polypeptide binding]; other site
990282008109	catalytic site [active]
990282008110	putative methyltransferase; Provisional; Region: PRK10864
990282008111	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
990282008112	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
990282008113	thioredoxin 2; Provisional; Region: PRK10996
990282008114	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
990282008115	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
990282008116	catalytic residues [active]
990282008117	Uncharacterized conserved protein [Function unknown]; Region: COG3148
990282008118	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
990282008119	CoA binding domain; Region: CoA_binding_2; pfam13380
990282008120	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
990282008121	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
990282008122	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
990282008123	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282008124	Coenzyme A binding pocket [chemical binding]; other site
990282008125	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
990282008126	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
990282008127	domain interface [polypeptide binding]; other site
990282008128	putative active site [active]
990282008129	catalytic site [active]
990282008130	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
990282008131	domain interface [polypeptide binding]; other site
990282008132	putative active site [active]
990282008133	catalytic site [active]
990282008134	lipoprotein; Provisional; Region: PRK10759
990282008135	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
990282008136	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282008137	putative substrate translocation pore; other site
990282008138	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
990282008139	protein disaggregation chaperone; Provisional; Region: PRK10865
990282008140	Clp amino terminal domain; Region: Clp_N; pfam02861
990282008141	Clp amino terminal domain; Region: Clp_N; pfam02861
990282008142	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282008143	Walker A motif; other site
990282008144	ATP binding site [chemical binding]; other site
990282008145	Walker B motif; other site
990282008146	arginine finger; other site
990282008147	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282008148	Walker A motif; other site
990282008149	ATP binding site [chemical binding]; other site
990282008150	Walker B motif; other site
990282008151	arginine finger; other site
990282008152	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
990282008153	hypothetical protein; Provisional; Region: PRK10723
990282008154	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
990282008155	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
990282008156	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
990282008157	RNA binding surface [nucleotide binding]; other site
990282008158	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
990282008159	active site
990282008160	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
990282008161	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
990282008162	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
990282008163	30S subunit binding site; other site
990282008164	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
990282008165	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
990282008166	Prephenate dehydratase; Region: PDT; pfam00800
990282008167	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
990282008168	putative L-Phe binding site [chemical binding]; other site
990282008169	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
990282008170	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
990282008171	Chorismate mutase type II; Region: CM_2; cl00693
990282008172	prephenate dehydrogenase; Validated; Region: PRK08507
990282008173	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
990282008174	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
990282008175	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
990282008176	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
990282008177	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
990282008178	metal binding site [ion binding]; metal-binding site
990282008179	active site
990282008180	I-site; other site
990282008181	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
990282008182	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
990282008183	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
990282008184	RimM N-terminal domain; Region: RimM; pfam01782
990282008185	PRC-barrel domain; Region: PRC; pfam05239
990282008186	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
990282008187	signal recognition particle protein; Provisional; Region: PRK10867
990282008188	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
990282008189	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
990282008190	P loop; other site
990282008191	GTP binding site [chemical binding]; other site
990282008192	Signal peptide binding domain; Region: SRP_SPB; pfam02978
990282008193	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
990282008194	hypothetical protein; Provisional; Region: PRK11573
990282008195	Domain of unknown function DUF21; Region: DUF21; pfam01595
990282008196	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
990282008197	Transporter associated domain; Region: CorC_HlyC; smart01091
990282008198	potential frameshift: common BLAST hit: gi|198246197|ref|YP_002216690.1| heat shock protein GrpE
990282008199	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
990282008200	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
990282008201	recombination and repair protein; Provisional; Region: PRK10869
990282008202	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
990282008203	Walker A/P-loop; other site
990282008204	ATP binding site [chemical binding]; other site
990282008205	Q-loop/lid; other site
990282008206	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
990282008207	ABC transporter signature motif; other site
990282008208	Walker B; other site
990282008209	D-loop; other site
990282008210	H-loop/switch region; other site
990282008211	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
990282008212	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
990282008213	hypothetical protein; Validated; Region: PRK01777
990282008214	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
990282008215	putative coenzyme Q binding site [chemical binding]; other site
990282008216	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
990282008217	SmpB-tmRNA interface; other site
990282008218	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282008219	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282008220	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282008221	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282008222	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282008223	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282008224	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282008225	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282008226	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282008227	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282008228	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282008229	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
990282008230	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282008231	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282008232	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
990282008233	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282008234	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282008235	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
990282008236	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
990282008237	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
990282008238	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
990282008239	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282008240	Walker A/P-loop; other site
990282008241	ATP binding site [chemical binding]; other site
990282008242	Q-loop/lid; other site
990282008243	ABC transporter signature motif; other site
990282008244	Walker B; other site
990282008245	D-loop; other site
990282008246	H-loop/switch region; other site
990282008247	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
990282008248	HlyD family secretion protein; Region: HlyD_3; pfam13437
990282008249	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
990282008250	active site
990282008251	Int/Topo IB signature motif; other site
990282008252	SEC-C motif; Region: SEC-C; pfam02810
990282008253	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
990282008254	Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG5519
990282008255	Predicted ATP-binding protein involved in virulence [General function prediction only]; Region: COG3950
990282008256	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
990282008257	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
990282008258	non-specific DNA binding site [nucleotide binding]; other site
990282008259	salt bridge; other site
990282008260	sequence-specific DNA binding site [nucleotide binding]; other site
990282008261	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
990282008262	Phosphotransferase system sorbitol-specific component IIC [Carbohydrate transport and metabolism]; Region: SrlA; COG3730
990282008263	Phosphotransferase system sorbitol-specific component IIA [Carbohydrate transport and metabolism]; Region: SrlB; COG3731
990282008264	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
990282008265	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
990282008266	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
990282008267	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
990282008268	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
990282008269	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
990282008270	Domain of unknown function (DUF3883); Region: DUF3883; pfam13020
990282008271	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
990282008272	active site
990282008273	dimer interface [polypeptide binding]; other site
990282008274	magnesium binding site [ion binding]; other site
990282008275	Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with...; Region: SIS_PHI; cd05005
990282008276	tetramer interface [polypeptide binding]; other site
990282008277	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
990282008278	active site
990282008279	Thermophilic glucose-6-phosphate isomerase and related metalloenzymes [Carbohydrate transport and metabolism / General function prediction only]; Region: COG2140
990282008280	Glucose-6-phosphate isomerase (GPI); Region: GPI; pfam06560
990282008281	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
990282008282	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
990282008283	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
990282008284	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
990282008285	Integrase; Region: Integrase_1; pfam12835
990282008286	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
990282008287	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
990282008288	DNA-binding interface [nucleotide binding]; DNA binding site
990282008289	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3972
990282008290	Family description; Region: UvrD_C_2; pfam13538
990282008291	Transposase; Region: HTH_Tnp_1; cl17663
990282008292	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
990282008293	putative transposase OrfB; Reviewed; Region: PHA02517
990282008294	HTH-like domain; Region: HTH_21; pfam13276
990282008295	Integrase core domain; Region: rve; pfam00665
990282008296	Integrase core domain; Region: rve_2; pfam13333
990282008297	Repressor of phase-1 flagellin; Region: Flag1_repress; pfam03614
990282008298	flagellin; Validated; Region: PRK08026
990282008299	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
990282008300	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
990282008301	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
990282008302	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
990282008303	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
990282008304	catalytic residues [active]
990282008305	catalytic nucleophile [active]
990282008306	Presynaptic Site I dimer interface [polypeptide binding]; other site
990282008307	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
990282008308	Synaptic Flat tetramer interface [polypeptide binding]; other site
990282008309	Synaptic Site I dimer interface [polypeptide binding]; other site
990282008310	DNA binding site [nucleotide binding]
990282008311	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
990282008312	DNA-binding interface [nucleotide binding]; DNA binding site
990282008313	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
990282008314	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
990282008315	homodimer interface [polypeptide binding]; other site
990282008316	active site
990282008317	TDP-binding site; other site
990282008318	acceptor substrate-binding pocket; other site
990282008319	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
990282008320	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282008321	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
990282008322	Walker A/P-loop; other site
990282008323	ATP binding site [chemical binding]; other site
990282008324	Q-loop/lid; other site
990282008325	ABC transporter signature motif; other site
990282008326	Walker B; other site
990282008327	D-loop; other site
990282008328	H-loop/switch region; other site
990282008329	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
990282008330	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
990282008331	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282008332	Walker A/P-loop; other site
990282008333	ATP binding site [chemical binding]; other site
990282008334	Q-loop/lid; other site
990282008335	ABC transporter signature motif; other site
990282008336	Walker B; other site
990282008337	D-loop; other site
990282008338	H-loop/switch region; other site
990282008339	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
990282008340	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
990282008341	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
990282008342	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
990282008343	outer membrane receptor FepA; Provisional; Region: PRK13528
990282008344	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
990282008345	N-terminal plug; other site
990282008346	ligand-binding site [chemical binding]; other site
990282008347	secreted effector protein PipB2; Provisional; Region: PRK15196
990282008348	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
990282008349	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
990282008350	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
990282008351	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
990282008352	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
990282008353	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
990282008354	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
990282008355	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
990282008356	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
990282008357	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
990282008358	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
990282008359	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
990282008360	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282008361	dimer interface [polypeptide binding]; other site
990282008362	phosphorylation site [posttranslational modification]
990282008363	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282008364	ATP binding site [chemical binding]; other site
990282008365	Mg2+ binding site [ion binding]; other site
990282008366	G-X-G motif; other site
990282008367	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
990282008368	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282008369	active site
990282008370	phosphorylation site [posttranslational modification]
990282008371	intermolecular recognition site; other site
990282008372	dimerization interface [polypeptide binding]; other site
990282008373	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
990282008374	DNA binding site [nucleotide binding]
990282008375	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
990282008376	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
990282008377	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
990282008378	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
990282008379	substrate binding pocket [chemical binding]; other site
990282008380	active site
990282008381	iron coordination sites [ion binding]; other site
990282008382	Predicted dehydrogenase [General function prediction only]; Region: COG0579
990282008383	hydroxyglutarate oxidase; Provisional; Region: PRK11728
990282008384	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
990282008385	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
990282008386	tetramerization interface [polypeptide binding]; other site
990282008387	NAD(P) binding site [chemical binding]; other site
990282008388	catalytic residues [active]
990282008389	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
990282008390	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
990282008391	inhibitor-cofactor binding pocket; inhibition site
990282008392	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282008393	catalytic residue [active]
990282008394	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
990282008395	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
990282008396	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282008397	DNA-binding site [nucleotide binding]; DNA binding site
990282008398	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
990282008399	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
990282008400	bacterial OsmY and nodulation domain; Region: BON; smart00749
990282008401	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
990282008402	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
990282008403	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
990282008404	dimerization interface [polypeptide binding]; other site
990282008405	putative DNA binding site [nucleotide binding]; other site
990282008406	Transcriptional regulators [Transcription]; Region: MarR; COG1846
990282008407	putative Zn2+ binding site [ion binding]; other site
990282008408	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
990282008409	active site residue [active]
990282008410	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
990282008411	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
990282008412	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
990282008413	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
990282008414	hypothetical protein; Provisional; Region: PRK10556
990282008415	hypothetical protein; Provisional; Region: PRK10132
990282008416	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
990282008417	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282008418	DNA-binding site [nucleotide binding]; DNA binding site
990282008419	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
990282008420	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282008421	homodimer interface [polypeptide binding]; other site
990282008422	catalytic residue [active]
990282008423	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
990282008424	Uncharacterized conserved protein [Function unknown]; Region: COG2128
990282008425	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
990282008426	catalytic residues [active]
990282008427	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
990282008428	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
990282008429	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
990282008430	Class I ribonucleotide reductase; Region: RNR_I; cd01679
990282008431	active site
990282008432	dimer interface [polypeptide binding]; other site
990282008433	catalytic residues [active]
990282008434	effector binding site; other site
990282008435	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
990282008436	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
990282008437	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
990282008438	dimer interface [polypeptide binding]; other site
990282008439	putative radical transfer pathway; other site
990282008440	diiron center [ion binding]; other site
990282008441	tyrosyl radical; other site
990282008442	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
990282008443	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
990282008444	Walker A/P-loop; other site
990282008445	ATP binding site [chemical binding]; other site
990282008446	Q-loop/lid; other site
990282008447	ABC transporter signature motif; other site
990282008448	Walker B; other site
990282008449	D-loop; other site
990282008450	H-loop/switch region; other site
990282008451	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
990282008452	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
990282008453	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282008454	dimer interface [polypeptide binding]; other site
990282008455	conserved gate region; other site
990282008456	putative PBP binding loops; other site
990282008457	ABC-ATPase subunit interface; other site
990282008458	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
990282008459	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
990282008460	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
990282008461	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282008462	transcriptional repressor MprA; Provisional; Region: PRK10870
990282008463	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
990282008464	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
990282008465	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
990282008466	HlyD family secretion protein; Region: HlyD_3; pfam13437
990282008467	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
990282008468	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282008469	putative substrate translocation pore; other site
990282008470	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282008471	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
990282008472	S-ribosylhomocysteinase; Provisional; Region: PRK02260
990282008473	glutamate--cysteine ligase; Provisional; Region: PRK02107
990282008474	Predicted membrane protein [Function unknown]; Region: COG1238
990282008475	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
990282008476	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282008477	motif II; other site
990282008478	carbon storage regulator; Provisional; Region: PRK01712
990282008479	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
990282008480	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
990282008481	motif 1; other site
990282008482	active site
990282008483	motif 2; other site
990282008484	motif 3; other site
990282008485	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
990282008486	DHHA1 domain; Region: DHHA1; pfam02272
990282008487	recombination regulator RecX; Reviewed; Region: recX; PRK00117
990282008488	recombinase A; Provisional; Region: recA; PRK09354
990282008489	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
990282008490	hexamer interface [polypeptide binding]; other site
990282008491	Walker A motif; other site
990282008492	ATP binding site [chemical binding]; other site
990282008493	Walker B motif; other site
990282008494	hypothetical protein; Validated; Region: PRK03661
990282008495	Transglycosylase SLT domain; Region: SLT_2; pfam13406
990282008496	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
990282008497	N-acetyl-D-glucosamine binding site [chemical binding]; other site
990282008498	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
990282008499	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
990282008500	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
990282008501	Nucleoside recognition; Region: Gate; pfam07670
990282008502	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
990282008503	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
990282008504	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
990282008505	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
990282008506	putative NAD(P) binding site [chemical binding]; other site
990282008507	active site
990282008508	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
990282008509	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
990282008510	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
990282008511	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
990282008512	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
990282008513	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
990282008514	putative active site [active]
990282008515	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
990282008516	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
990282008517	GAF domain; Region: GAF; pfam01590
990282008518	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282008519	Walker A motif; other site
990282008520	ATP binding site [chemical binding]; other site
990282008521	Walker B motif; other site
990282008522	arginine finger; other site
990282008523	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
990282008524	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
990282008525	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
990282008526	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
990282008527	iron binding site [ion binding]; other site
990282008528	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
990282008529	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
990282008530	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
990282008531	Acylphosphatase; Region: Acylphosphatase; pfam00708
990282008532	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
990282008533	HypF finger; Region: zf-HYPF; pfam07503
990282008534	HypF finger; Region: zf-HYPF; pfam07503
990282008535	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
990282008536	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
990282008537	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
990282008538	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
990282008539	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
990282008540	nickel binding site [ion binding]; other site
990282008541	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
990282008542	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
990282008543	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
990282008544	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
990282008545	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
990282008546	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
990282008547	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
990282008548	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
990282008549	NADH dehydrogenase; Region: NADHdh; cl00469
990282008550	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
990282008551	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
990282008552	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
990282008553	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
990282008554	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
990282008555	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
990282008556	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
990282008557	hydrogenase assembly chaperone; Provisional; Region: PRK10409
990282008558	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
990282008559	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
990282008560	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
990282008561	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
990282008562	dimerization interface [polypeptide binding]; other site
990282008563	ATP binding site [chemical binding]; other site
990282008564	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
990282008565	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
990282008566	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
990282008567	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282008568	Walker A motif; other site
990282008569	ATP binding site [chemical binding]; other site
990282008570	Walker B motif; other site
990282008571	arginine finger; other site
990282008572	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
990282008573	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
990282008574	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
990282008575	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
990282008576	metal binding site [ion binding]; metal-binding site
990282008577	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
990282008578	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
990282008579	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
990282008580	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
990282008581	ABC-ATPase subunit  interface; other site
990282008582	dimer interface [polypeptide binding]; other site
990282008583	putative PBP binding regions; other site
990282008584	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
990282008585	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
990282008586	ABC-ATPase subunit  interface; other site
990282008587	dimer interface [polypeptide binding]; other site
990282008588	putative PBP binding regions; other site
990282008589	effector protein YopJ; Provisional; Region: PRK15371
990282008590	transcriptional activator SprB; Provisional; Region: PRK15320
990282008591	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
990282008592	transcriptional regulator SirC; Provisional; Region: PRK15044
990282008593	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282008594	putative type III secretion system effector protein OrgC; Provisional; Region: PRK15321
990282008595	invasion protein OrgB; Provisional; Region: PRK15322
990282008596	type III secretion apparatus protein OrgA/MxiK; Region: OrgA_MxiK; TIGR02555
990282008597	invasion protein OrgA; Provisional; Region: PRK15323
990282008598	type III secretion system lipoprotein PrgK; Provisional; Region: PRK15324
990282008599	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
990282008600	type III secretion system needle complex protein PrgI; Provisional; Region: PRK15326
990282008601	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327
990282008602	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
990282008603	transcriptional regulator HilD; Provisional; Region: PRK15185
990282008604	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282008605	invasion protein regulator; Provisional; Region: PRK12370
990282008606	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
990282008607	DNA binding site [nucleotide binding]
990282008608	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
990282008609	binding surface
990282008610	TPR motif; other site
990282008611	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
990282008612	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
990282008613	N-acetyl-D-glucosamine binding site [chemical binding]; other site
990282008614	catalytic residue [active]
990282008615	pathogenicity island 1 effector protein StpP; Provisional; Region: PRK15375
990282008616	SicP binding; Region: SicP-binding; pfam09119
990282008617	GTPase-activating protein (GAP) domain found in bacterial cytotoxins, ExoS, SptP, and YopE. Part of protein secretion system; stimulates Rac1- dependent cytoskeletal changes that promote bacterial internalization; Region: ToxGAP; cd00219
990282008618	switch II binding region; other site
990282008619	Rac1 P-loop interaction site [polypeptide binding]; other site
990282008620	GTP binding residues [chemical binding]; other site
990282008621	switch I binding region; other site
990282008622	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cd00047
990282008623	active site
990282008624	chaperone protein SicP; Provisional; Region: PRK15329
990282008625	putative acyl carrier protein IacP; Validated; Region: PRK08172
990282008626	pathogenicity island 1 effector protein SipA; Provisional; Region: PRK15376
990282008627	cell invasion protein SipD; Provisional; Region: PRK15330
990282008628	pathogenicity island 1 effector protein SipC; Provisional; Region: PRK15373
990282008629	pathogenicity island 1 effector protein SipB; Provisional; Region: PRK15374
990282008630	chaperone protein SicA; Provisional; Region: PRK15331
990282008631	Tetratricopeptide repeat; Region: TPR_3; pfam07720
990282008632	Tetratricopeptide repeat; Region: TPR_3; pfam07720
990282008633	type III secretion system protein SpaS; Validated; Region: PRK08156
990282008634	type III secretion system protein SpaR; Provisional; Region: PRK15332
990282008635	type III secretion system protein SpaQ; Provisional; Region: PRK15333
990282008636	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
990282008637	type III secretion system protein SpaO; Validated; Region: PRK08158
990282008638	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
990282008639	antigen presentation protein SpaN; Provisional; Region: PRK15334
990282008640	Surface presentation of antigens protein; Region: SPAN; pfam02510
990282008641	Salmonella surface presentation of antigen gene type M protein; Region: SPAM; pfam02090
990282008642	ATP synthase SpaL; Validated; Region: PRK08149
990282008643	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
990282008644	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
990282008645	Walker A motif; other site
990282008646	ATP binding site [chemical binding]; other site
990282008647	Walker B motif; other site
990282008648	type III secretion system chaperone SpaK; Provisional; Region: PRK15336
990282008649	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
990282008650	type III secretion system protein InvA; Provisional; Region: PRK15337
990282008651	type III secretion system regulator InvE; Provisional; Region: PRK15338
990282008652	type III secretion regulator YopN/LcrE/InvE/MxiC; Region: LcrE; TIGR02568
990282008653	type III secretion system outer membrane pore InvG; Provisional; Region: PRK15339
990282008654	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
990282008655	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
990282008656	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
990282008657	transcriptional regulator InvF; Provisional; Region: PRK15340
990282008658	InvH outer membrane lipoprotein; Region: InvH; pfam04741
990282008659	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
990282008660	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
990282008661	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
990282008662	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
990282008663	active site
990282008664	metal binding site [ion binding]; metal-binding site
990282008665	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
990282008666	MutS domain I; Region: MutS_I; pfam01624
990282008667	MutS domain II; Region: MutS_II; pfam05188
990282008668	MutS domain III; Region: MutS_III; pfam05192
990282008669	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
990282008670	Walker A/P-loop; other site
990282008671	ATP binding site [chemical binding]; other site
990282008672	Q-loop/lid; other site
990282008673	ABC transporter signature motif; other site
990282008674	Walker B; other site
990282008675	D-loop; other site
990282008676	H-loop/switch region; other site
990282008677	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
990282008678	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282008679	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282008680	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
990282008681	putative effector binding pocket; other site
990282008682	dimerization interface [polypeptide binding]; other site
990282008683	GntP family permease; Region: GntP_permease; pfam02447
990282008684	fructuronate transporter; Provisional; Region: PRK10034; cl15264
990282008685	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
990282008686	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
990282008687	putative NAD(P) binding site [chemical binding]; other site
990282008688	active site
990282008689	putative substrate binding site [chemical binding]; other site
990282008690	hypothetical protein; Provisional; Region: PRK09989
990282008691	putative aldolase; Validated; Region: PRK08130
990282008692	intersubunit interface [polypeptide binding]; other site
990282008693	active site
990282008694	Zn2+ binding site [ion binding]; other site
990282008695	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
990282008696	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
990282008697	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
990282008698	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
990282008699	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
990282008700	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
990282008701	MarR family; Region: MarR_2; cl17246
990282008702	Transcriptional regulators [Transcription]; Region: MarR; COG1846
990282008703	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
990282008704	Flavoprotein; Region: Flavoprotein; pfam02441
990282008705	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
990282008706	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
990282008707	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
990282008708	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
990282008709	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
990282008710	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
990282008711	DNA binding residues [nucleotide binding]
990282008712	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
990282008713	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
990282008714	Peptidase family M23; Region: Peptidase_M23; pfam01551
990282008715	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
990282008716	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282008717	S-adenosylmethionine binding site [chemical binding]; other site
990282008718	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
990282008719	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
990282008720	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
990282008721	Permutation of conserved domain; other site
990282008722	active site
990282008723	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
990282008724	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
990282008725	homotrimer interaction site [polypeptide binding]; other site
990282008726	zinc binding site [ion binding]; other site
990282008727	CDP-binding sites; other site
990282008728	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
990282008729	substrate binding site; other site
990282008730	dimer interface; other site
990282008731	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
990282008732	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
990282008733	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
990282008734	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
990282008735	ligand-binding site [chemical binding]; other site
990282008736	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
990282008737	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
990282008738	CysD dimerization site [polypeptide binding]; other site
990282008739	G1 box; other site
990282008740	putative GEF interaction site [polypeptide binding]; other site
990282008741	GTP/Mg2+ binding site [chemical binding]; other site
990282008742	Switch I region; other site
990282008743	G2 box; other site
990282008744	G3 box; other site
990282008745	Switch II region; other site
990282008746	G4 box; other site
990282008747	G5 box; other site
990282008748	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
990282008749	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
990282008750	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
990282008751	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
990282008752	Active Sites [active]
990282008753	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
990282008754	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
990282008755	metal binding site [ion binding]; metal-binding site
990282008756	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09648
990282008757	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
990282008758	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09727
990282008759	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
990282008760	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
990282008761	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cd09646
990282008762	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09731
990282008763	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
990282008764	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
990282008765	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
990282008766	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
990282008767	pathogenicity island 1 effector protein SopD; Provisional; Region: PRK15379
990282008768	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
990282008769	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
990282008770	Active Sites [active]
990282008771	sulfite reductase subunit beta; Provisional; Region: PRK13504
990282008772	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
990282008773	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
990282008774	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
990282008775	Flavodoxin; Region: Flavodoxin_1; pfam00258
990282008776	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
990282008777	FAD binding pocket [chemical binding]; other site
990282008778	FAD binding motif [chemical binding]; other site
990282008779	catalytic residues [active]
990282008780	NAD binding pocket [chemical binding]; other site
990282008781	phosphate binding motif [ion binding]; other site
990282008782	beta-alpha-beta structure motif; other site
990282008783	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
990282008784	active site
990282008785	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
990282008786	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
990282008787	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
990282008788	enolase; Provisional; Region: eno; PRK00077
990282008789	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
990282008790	dimer interface [polypeptide binding]; other site
990282008791	metal binding site [ion binding]; metal-binding site
990282008792	substrate binding pocket [chemical binding]; other site
990282008793	CTP synthetase; Validated; Region: pyrG; PRK05380
990282008794	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
990282008795	Catalytic site [active]
990282008796	active site
990282008797	UTP binding site [chemical binding]; other site
990282008798	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
990282008799	active site
990282008800	putative oxyanion hole; other site
990282008801	catalytic triad [active]
990282008802	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
990282008803	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
990282008804	homodimer interface [polypeptide binding]; other site
990282008805	metal binding site [ion binding]; metal-binding site
990282008806	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
990282008807	homodimer interface [polypeptide binding]; other site
990282008808	active site
990282008809	putative chemical substrate binding site [chemical binding]; other site
990282008810	metal binding site [ion binding]; metal-binding site
990282008811	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription]; Region: COG3609
990282008812	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
990282008813	HD domain; Region: HD_4; pfam13328
990282008814	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
990282008815	synthetase active site [active]
990282008816	NTP binding site [chemical binding]; other site
990282008817	metal binding site [ion binding]; metal-binding site
990282008818	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
990282008819	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
990282008820	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
990282008821	TRAM domain; Region: TRAM; pfam01938
990282008822	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282008823	S-adenosylmethionine binding site [chemical binding]; other site
990282008824	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
990282008825	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
990282008826	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
990282008827	dimerization interface [polypeptide binding]; other site
990282008828	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282008829	dimer interface [polypeptide binding]; other site
990282008830	phosphorylation site [posttranslational modification]
990282008831	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282008832	ATP binding site [chemical binding]; other site
990282008833	Mg2+ binding site [ion binding]; other site
990282008834	G-X-G motif; other site
990282008835	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
990282008836	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282008837	active site
990282008838	phosphorylation site [posttranslational modification]
990282008839	intermolecular recognition site; other site
990282008840	dimerization interface [polypeptide binding]; other site
990282008841	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
990282008842	putative binding surface; other site
990282008843	active site
990282008844	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
990282008845	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
990282008846	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
990282008847	active site
990282008848	tetramer interface [polypeptide binding]; other site
990282008849	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
990282008850	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
990282008851	active site
990282008852	tetramer interface [polypeptide binding]; other site
990282008853	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282008854	D-galactonate transporter; Region: 2A0114; TIGR00893
990282008855	putative substrate translocation pore; other site
990282008856	flavodoxin; Provisional; Region: PRK08105
990282008857	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
990282008858	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
990282008859	probable active site [active]
990282008860	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
990282008861	SecY interacting protein Syd; Provisional; Region: PRK04968
990282008862	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
990282008863	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
990282008864	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
990282008865	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
990282008866	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
990282008867	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
990282008868	serine transporter; Region: stp; TIGR00814
990282008869	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
990282008870	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
990282008871	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
990282008872	flap endonuclease-like protein; Provisional; Region: PRK09482
990282008873	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
990282008874	active site
990282008875	metal binding site 1 [ion binding]; metal-binding site
990282008876	putative 5' ssDNA interaction site; other site
990282008877	metal binding site 3; metal-binding site
990282008878	metal binding site 2 [ion binding]; metal-binding site
990282008879	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
990282008880	putative DNA binding site [nucleotide binding]; other site
990282008881	putative metal binding site [ion binding]; other site
990282008882	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
990282008883	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
990282008884	dimer interface [polypeptide binding]; other site
990282008885	active site
990282008886	metal binding site [ion binding]; metal-binding site
990282008887	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
990282008888	intersubunit interface [polypeptide binding]; other site
990282008889	active site
990282008890	Zn2+ binding site [ion binding]; other site
990282008891	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
990282008892	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282008893	putative substrate translocation pore; other site
990282008894	L-fucose isomerase; Provisional; Region: fucI; PRK10991
990282008895	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
990282008896	hexamer (dimer of trimers) interface [polypeptide binding]; other site
990282008897	trimer interface [polypeptide binding]; other site
990282008898	substrate binding site [chemical binding]; other site
990282008899	Mn binding site [ion binding]; other site
990282008900	L-fuculokinase; Provisional; Region: PRK10331
990282008901	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
990282008902	nucleotide binding site [chemical binding]; other site
990282008903	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
990282008904	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
990282008905	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
990282008906	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
990282008907	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
990282008908	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
990282008909	hypothetical protein; Provisional; Region: PRK10873
990282008910	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
990282008911	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282008912	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
990282008913	dimerization interface [polypeptide binding]; other site
990282008914	substrate binding pocket [chemical binding]; other site
990282008915	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
990282008916	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
990282008917	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
990282008918	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
990282008919	catalytic residue [active]
990282008920	CsdA-binding activator; Provisional; Region: PRK15019
990282008921	Predicted permeases [General function prediction only]; Region: RarD; COG2962
990282008922	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
990282008923	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
990282008924	putative ATP binding site [chemical binding]; other site
990282008925	putative substrate interface [chemical binding]; other site
990282008926	murein transglycosylase A; Provisional; Region: mltA; PRK11162
990282008927	murein hydrolase B; Provisional; Region: PRK10760; cl17906
990282008928	MltA specific insert domain; Region: MltA; pfam03562
990282008929	3D domain; Region: 3D; pfam06725
990282008930	AMIN domain; Region: AMIN; pfam11741
990282008931	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
990282008932	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
990282008933	active site
990282008934	metal binding site [ion binding]; metal-binding site
990282008935	N-acetylglutamate synthase; Validated; Region: PRK05279
990282008936	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
990282008937	putative feedback inhibition sensing region; other site
990282008938	putative nucleotide binding site [chemical binding]; other site
990282008939	putative substrate binding site [chemical binding]; other site
990282008940	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282008941	Coenzyme A binding pocket [chemical binding]; other site
990282008942	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
990282008943	AAA domain; Region: AAA_30; pfam13604
990282008944	Family description; Region: UvrD_C_2; pfam13538
990282008945	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
990282008946	protease3; Provisional; Region: PRK15101
990282008947	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
990282008948	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
990282008949	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
990282008950	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
990282008951	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
990282008952	hypothetical protein; Provisional; Region: PRK10332
990282008953	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
990282008954	hypothetical protein; Provisional; Region: PRK11521
990282008955	hypothetical protein; Provisional; Region: PRK10557
990282008956	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
990282008957	hypothetical protein; Provisional; Region: PRK10506
990282008958	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
990282008959	thymidylate synthase; Reviewed; Region: thyA; PRK01827
990282008960	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
990282008961	dimerization interface [polypeptide binding]; other site
990282008962	active site
990282008963	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
990282008964	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
990282008965	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
990282008966	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
990282008967	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
990282008968	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
990282008969	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
990282008970	putative active site [active]
990282008971	Ap4A binding site [chemical binding]; other site
990282008972	nudix motif; other site
990282008973	putative metal binding site [ion binding]; other site
990282008974	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
990282008975	putative DNA-binding cleft [nucleotide binding]; other site
990282008976	putative DNA clevage site; other site
990282008977	molecular lever; other site
990282008978	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
990282008979	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
990282008980	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
990282008981	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
990282008982	active site
990282008983	catalytic tetrad [active]
990282008984	lysophospholipid transporter LplT; Provisional; Region: PRK11195
990282008985	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282008986	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
990282008987	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
990282008988	putative acyl-acceptor binding pocket; other site
990282008989	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
990282008990	acyl-activating enzyme (AAE) consensus motif; other site
990282008991	putative AMP binding site [chemical binding]; other site
990282008992	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
990282008993	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
990282008994	DNA binding site [nucleotide binding]
990282008995	domain linker motif; other site
990282008996	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
990282008997	dimerization interface (closed form) [polypeptide binding]; other site
990282008998	ligand binding site [chemical binding]; other site
990282008999	Transcriptional regulators [Transcription]; Region: PurR; COG1609
990282009000	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
990282009001	DNA binding site [nucleotide binding]
990282009002	domain linker motif; other site
990282009003	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
990282009004	dimerization interface (closed form) [polypeptide binding]; other site
990282009005	ligand binding site [chemical binding]; other site
990282009006	diaminopimelate decarboxylase; Provisional; Region: PRK11165
990282009007	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
990282009008	active site
990282009009	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
990282009010	substrate binding site [chemical binding]; other site
990282009011	catalytic residues [active]
990282009012	dimer interface [polypeptide binding]; other site
990282009013	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
990282009014	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282009015	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
990282009016	dimerization interface [polypeptide binding]; other site
990282009017	putative racemase; Provisional; Region: PRK10200
990282009018	aspartate racemase; Region: asp_race; TIGR00035
990282009019	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
990282009020	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282009021	putative substrate translocation pore; other site
990282009022	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282009023	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
990282009024	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
990282009025	NADP binding site [chemical binding]; other site
990282009026	homodimer interface [polypeptide binding]; other site
990282009027	active site
990282009028	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
990282009029	putative acyltransferase; Provisional; Region: PRK05790
990282009030	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
990282009031	dimer interface [polypeptide binding]; other site
990282009032	active site
990282009033	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282009034	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282009035	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
990282009036	dimerization interface [polypeptide binding]; other site
990282009037	Predicted membrane protein [Function unknown]; Region: COG4125
990282009038	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
990282009039	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
990282009040	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
990282009041	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
990282009042	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
990282009043	putative metal binding site [ion binding]; other site
990282009044	putative homodimer interface [polypeptide binding]; other site
990282009045	putative homotetramer interface [polypeptide binding]; other site
990282009046	putative homodimer-homodimer interface [polypeptide binding]; other site
990282009047	putative allosteric switch controlling residues; other site
990282009048	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
990282009049	High-affinity nickel-transport protein; Region: NicO; cl00964
990282009050	transcriptional activator SprB; Provisional; Region: PRK15320
990282009051	Holliday junction DNA helicase RuvA; Provisional; Region: ruvA; PRK14600
990282009052	Protein of unknown function (DUF1401); Region: DUF1401; pfam07180
990282009053	Fimbrial protein; Region: Fimbrial; pfam00419
990282009054	fimbrial chaperone protein StdC; Provisional; Region: PRK15254
990282009055	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
990282009056	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
990282009057	fimbrial outer membrane usher protein StdB; Provisional; Region: PRK15255
990282009058	PapC N-terminal domain; Region: PapC_N; pfam13954
990282009059	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
990282009060	PapC C-terminal domain; Region: PapC_C; pfam13953
990282009061	fimbrial protein StdA; Provisional; Region: PRK15210
990282009062	hypothetical protein; Provisional; Region: PRK10316
990282009063	YfdX protein; Region: YfdX; pfam10938
990282009064	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
990282009065	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
990282009066	oligomeric interface; other site
990282009067	putative active site [active]
990282009068	homodimer interface [polypeptide binding]; other site
990282009069	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
990282009070	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
990282009071	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
990282009072	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
990282009073	Peptidase family M23; Region: Peptidase_M23; pfam01551
990282009074	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
990282009075	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
990282009076	active site
990282009077	metal binding site [ion binding]; metal-binding site
990282009078	nudix motif; other site
990282009079	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
990282009080	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
990282009081	dimer interface [polypeptide binding]; other site
990282009082	putative anticodon binding site; other site
990282009083	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
990282009084	motif 1; other site
990282009085	active site
990282009086	motif 2; other site
990282009087	motif 3; other site
990282009088	This domain is found in peptide chain release factors; Region: PCRF; smart00937
990282009089	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
990282009090	RF-1 domain; Region: RF-1; pfam00472
990282009091	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
990282009092	DHH family; Region: DHH; pfam01368
990282009093	DHHA1 domain; Region: DHHA1; pfam02272
990282009094	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
990282009095	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
990282009096	dimerization domain [polypeptide binding]; other site
990282009097	dimer interface [polypeptide binding]; other site
990282009098	catalytic residues [active]
990282009099	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
990282009100	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
990282009101	active site
990282009102	Int/Topo IB signature motif; other site
990282009103	flavodoxin FldB; Provisional; Region: PRK12359
990282009104	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
990282009105	hypothetical protein; Provisional; Region: PRK10878
990282009106	putative global regulator; Reviewed; Region: PRK09559
990282009107	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
990282009108	hemolysin; Provisional; Region: PRK15087
990282009109	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
990282009110	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
990282009111	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
990282009112	beta-galactosidase; Region: BGL; TIGR03356
990282009113	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; pfam13557
990282009114	glycine dehydrogenase; Provisional; Region: PRK05367
990282009115	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
990282009116	tetramer interface [polypeptide binding]; other site
990282009117	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282009118	catalytic residue [active]
990282009119	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
990282009120	tetramer interface [polypeptide binding]; other site
990282009121	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282009122	catalytic residue [active]
990282009123	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
990282009124	lipoyl attachment site [posttranslational modification]; other site
990282009125	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
990282009126	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
990282009127	oxidoreductase; Provisional; Region: PRK08013
990282009128	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
990282009129	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
990282009130	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
990282009131	proline aminopeptidase P II; Provisional; Region: PRK10879
990282009132	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
990282009133	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
990282009134	active site
990282009135	hypothetical protein; Reviewed; Region: PRK01736
990282009136	Z-ring-associated protein; Provisional; Region: PRK10972
990282009137	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
990282009138	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
990282009139	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
990282009140	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
990282009141	ligand binding site [chemical binding]; other site
990282009142	NAD binding site [chemical binding]; other site
990282009143	tetramer interface [polypeptide binding]; other site
990282009144	catalytic site [active]
990282009145	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
990282009146	L-serine binding site [chemical binding]; other site
990282009147	ACT domain interface; other site
990282009148	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
990282009149	tetramer (dimer of dimers) interface [polypeptide binding]; other site
990282009150	active site
990282009151	dimer interface [polypeptide binding]; other site
990282009152	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
990282009153	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282009154	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
990282009155	putative dimerization interface [polypeptide binding]; other site
990282009156	Uncharacterized conserved protein [Function unknown]; Region: COG2968
990282009157	oxidative stress defense protein; Provisional; Region: PRK11087
990282009158	arginine exporter protein; Provisional; Region: PRK09304
990282009159	mechanosensitive channel MscS; Provisional; Region: PRK10334
990282009160	Mechanosensitive ion channel; Region: MS_channel; pfam00924
990282009161	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
990282009162	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
990282009163	active site
990282009164	intersubunit interface [polypeptide binding]; other site
990282009165	zinc binding site [ion binding]; other site
990282009166	Na+ binding site [ion binding]; other site
990282009167	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
990282009168	Phosphoglycerate kinase; Region: PGK; pfam00162
990282009169	substrate binding site [chemical binding]; other site
990282009170	hinge regions; other site
990282009171	ADP binding site [chemical binding]; other site
990282009172	catalytic site [active]
990282009173	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
990282009174	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
990282009175	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
990282009176	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
990282009177	trimer interface [polypeptide binding]; other site
990282009178	putative Zn binding site [ion binding]; other site
990282009179	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
990282009180	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
990282009181	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
990282009182	Walker A/P-loop; other site
990282009183	ATP binding site [chemical binding]; other site
990282009184	Q-loop/lid; other site
990282009185	ABC transporter signature motif; other site
990282009186	Walker B; other site
990282009187	D-loop; other site
990282009188	H-loop/switch region; other site
990282009189	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
990282009190	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
990282009191	Walker A/P-loop; other site
990282009192	ATP binding site [chemical binding]; other site
990282009193	Q-loop/lid; other site
990282009194	ABC transporter signature motif; other site
990282009195	Walker B; other site
990282009196	D-loop; other site
990282009197	H-loop/switch region; other site
990282009198	transketolase; Reviewed; Region: PRK12753
990282009199	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
990282009200	TPP-binding site [chemical binding]; other site
990282009201	dimer interface [polypeptide binding]; other site
990282009202	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
990282009203	PYR/PP interface [polypeptide binding]; other site
990282009204	dimer interface [polypeptide binding]; other site
990282009205	TPP binding site [chemical binding]; other site
990282009206	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
990282009207	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
990282009208	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
990282009209	agmatinase; Region: agmatinase; TIGR01230
990282009210	oligomer interface [polypeptide binding]; other site
990282009211	putative active site [active]
990282009212	Mn binding site [ion binding]; other site
990282009213	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
990282009214	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
990282009215	Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055
990282009216	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
990282009217	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
990282009218	putative NAD(P) binding site [chemical binding]; other site
990282009219	catalytic Zn binding site [ion binding]; other site
990282009220	structural Zn binding site [ion binding]; other site
990282009221	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
990282009222	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
990282009223	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
990282009224	Transcriptional regulators [Transcription]; Region: FadR; COG2186
990282009225	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282009226	DNA-binding site [nucleotide binding]; DNA binding site
990282009227	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
990282009228	DNA phosphorothioation-dependent restriction protein DptH; Region: dnd_assoc_2; TIGR03237
990282009229	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
990282009230	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
990282009231	dimer interface [polypeptide binding]; other site
990282009232	active site
990282009233	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
990282009234	catalytic residues [active]
990282009235	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
990282009236	Virulence promoting factor; Region: YqgB; pfam11036
990282009237	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
990282009238	S-adenosylmethionine synthetase; Validated; Region: PRK05250
990282009239	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
990282009240	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
990282009241	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
990282009242	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
990282009243	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282009244	putative substrate translocation pore; other site
990282009245	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282009246	hypothetical protein; Provisional; Region: PRK04860
990282009247	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
990282009248	DNA-specific endonuclease I; Provisional; Region: PRK15137
990282009249	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
990282009250	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
990282009251	RNA methyltransferase, RsmE family; Region: TIGR00046
990282009252	glutathione synthetase; Provisional; Region: PRK05246
990282009253	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
990282009254	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
990282009255	hypothetical protein; Validated; Region: PRK00228
990282009256	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
990282009257	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
990282009258	Transcriptional regulator [Transcription]; Region: IclR; COG1414
990282009259	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
990282009260	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
990282009261	Walker A motif; other site
990282009262	ATP binding site [chemical binding]; other site
990282009263	Walker B motif; other site
990282009264	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
990282009265	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
990282009266	catalytic residue [active]
990282009267	YGGT family; Region: YGGT; pfam02325
990282009268	YGGT family; Region: YGGT; pfam02325
990282009269	hypothetical protein; Validated; Region: PRK05090
990282009270	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
990282009271	active site
990282009272	dimerization interface [polypeptide binding]; other site
990282009273	HemN family oxidoreductase; Provisional; Region: PRK05660
990282009274	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282009275	FeS/SAM binding site; other site
990282009276	HemN C-terminal domain; Region: HemN_C; pfam06969
990282009277	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
990282009278	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
990282009279	homodimer interface [polypeptide binding]; other site
990282009280	active site
990282009281	hypothetical protein; Provisional; Region: PRK10626
990282009282	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
990282009283	hypothetical protein; Provisional; Region: PRK11702
990282009284	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
990282009285	adenine DNA glycosylase; Provisional; Region: PRK10880
990282009286	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
990282009287	minor groove reading motif; other site
990282009288	helix-hairpin-helix signature motif; other site
990282009289	substrate binding pocket [chemical binding]; other site
990282009290	active site
990282009291	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
990282009292	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
990282009293	DNA binding and oxoG recognition site [nucleotide binding]
990282009294	oxidative damage protection protein; Provisional; Region: PRK05408
990282009295	murein transglycosylase C; Provisional; Region: mltC; PRK11671
990282009296	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
990282009297	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
990282009298	N-acetyl-D-glucosamine binding site [chemical binding]; other site
990282009299	catalytic residue [active]
990282009300	ornithine decarboxylase; Provisional; Region: PRK13578
990282009301	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
990282009302	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
990282009303	homodimer interface [polypeptide binding]; other site
990282009304	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282009305	catalytic residue [active]
990282009306	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
990282009307	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
990282009308	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253
990282009309	dimer interface [polypeptide binding]; other site
990282009310	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
990282009311	metal binding site [ion binding]; metal-binding site
990282009312	Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427
990282009313	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
990282009314	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
990282009315	FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2  has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal...; Region: FkbR2; cd03451
990282009316	putative active site [active]
990282009317	putative catalytic site [active]
990282009318	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
990282009319	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
990282009320	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282009321	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
990282009322	putative dimerization interface [polypeptide binding]; other site
990282009323	putative substrate binding pocket [chemical binding]; other site
990282009324	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
990282009325	Sulfatase; Region: Sulfatase; pfam00884
990282009326	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
990282009327	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282009328	FeS/SAM binding site; other site
990282009329	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
990282009330	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
990282009331	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282009332	DNA binding residues [nucleotide binding]
990282009333	dimerization interface [polypeptide binding]; other site
990282009334	Protein of unknown function (DUF3156); Region: DUF3156; pfam11354
990282009335	Amino acid permease; Region: AA_permease_2; pfam13520
990282009336	Predicted enzyme of the cupin superfamily [General function prediction only]; Region: COG3450
990282009337	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
990282009338	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
990282009339	Escherichia coli NAD+-dependent phenylacetaldehyde dehydrogenase PadA-like; Region: ALDH_PADH_NahF; cd07113
990282009340	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
990282009341	NAD(P) binding site [chemical binding]; other site
990282009342	catalytic residues [active]
990282009343	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
990282009344	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
990282009345	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
990282009346	active site
990282009347	catalytic site [active]
990282009348	Zn binding site [ion binding]; other site
990282009349	tetramer interface [polypeptide binding]; other site
990282009350	Predicted amidohydrolase [General function prediction only]; Region: COG0388
990282009351	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
990282009352	putative active site [active]
990282009353	catalytic triad [active]
990282009354	putative dimer interface [polypeptide binding]; other site
990282009355	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282009356	D-galactonate transporter; Region: 2A0114; TIGR00893
990282009357	putative substrate translocation pore; other site
990282009358	mannonate dehydratase; Provisional; Region: PRK03906
990282009359	mannonate dehydratase; Region: uxuA; TIGR00695
990282009360	D-mannonate oxidoreductase; Provisional; Region: PRK15037
990282009361	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
990282009362	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
990282009363	Glucuronate isomerase; Region: UxaC; pfam02614
990282009364	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
990282009365	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
990282009366	dimer interface [polypeptide binding]; other site
990282009367	putative CheW interface [polypeptide binding]; other site
990282009368	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
990282009369	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
990282009370	CHAP domain; Region: CHAP; pfam05257
990282009371	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
990282009372	putative S-transferase; Provisional; Region: PRK11752
990282009373	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
990282009374	C-terminal domain interface [polypeptide binding]; other site
990282009375	GSH binding site (G-site) [chemical binding]; other site
990282009376	dimer interface [polypeptide binding]; other site
990282009377	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
990282009378	dimer interface [polypeptide binding]; other site
990282009379	N-terminal domain interface [polypeptide binding]; other site
990282009380	active site
990282009381	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
990282009382	molybdate ABC transporter periplasmic molybdate-binding protein; Provisional; Region: PRK03537
990282009383	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
990282009384	putative ligand binding residues [chemical binding]; other site
990282009385	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
990282009386	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
990282009387	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
990282009388	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
990282009389	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
990282009390	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
990282009391	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
990282009392	putative substrate-binding site; other site
990282009393	nickel binding site [ion binding]; other site
990282009394	hydrogenase 2 large subunit; Provisional; Region: PRK10467
990282009395	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
990282009396	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
990282009397	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
990282009398	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
990282009399	4Fe-4S binding domain; Region: Fer4_6; pfam12837
990282009400	hydrogenase 2 small subunit; Provisional; Region: PRK10468
990282009401	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
990282009402	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
990282009403	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
990282009404	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
990282009405	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
990282009406	dimerization interface [polypeptide binding]; other site
990282009407	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
990282009408	dimer interface [polypeptide binding]; other site
990282009409	putative CheW interface [polypeptide binding]; other site
990282009410	hypothetical protein; Provisional; Region: PRK05208
990282009411	oxidoreductase; Provisional; Region: PRK07985
990282009412	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
990282009413	NAD binding site [chemical binding]; other site
990282009414	metal binding site [ion binding]; metal-binding site
990282009415	active site
990282009416	biopolymer transport protein ExbD; Provisional; Region: PRK11267
990282009417	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
990282009418	biopolymer transport protein ExbB; Provisional; Region: PRK10414
990282009419	cystathionine beta-lyase; Provisional; Region: PRK08114
990282009420	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
990282009421	homodimer interface [polypeptide binding]; other site
990282009422	substrate-cofactor binding pocket; other site
990282009423	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282009424	catalytic residue [active]
990282009425	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
990282009426	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
990282009427	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
990282009428	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
990282009429	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282009430	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282009431	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
990282009432	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
990282009433	dimer interface [polypeptide binding]; other site
990282009434	active site
990282009435	metal binding site [ion binding]; metal-binding site
990282009436	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
990282009437	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
990282009438	active site
990282009439	catalytic tetrad [active]
990282009440	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
990282009441	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
990282009442	transmembrane helices; other site
990282009443	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
990282009444	nucleotide binding site/active site [active]
990282009445	catalytic residue [active]
990282009446	hypothetical protein; Provisional; Region: PRK01254
990282009447	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
990282009448	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
990282009449	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
990282009450	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
990282009451	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
990282009452	DctM-like transporters; Region: DctM; pfam06808
990282009453	TRAP transporter, DctM subunit; Region: dctM; TIGR00786
990282009454	FtsI repressor; Provisional; Region: PRK10883
990282009455	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
990282009456	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
990282009457	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
990282009458	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
990282009459	putative acyl-acceptor binding pocket; other site
990282009460	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
990282009461	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
990282009462	CAP-like domain; other site
990282009463	active site
990282009464	primary dimer interface [polypeptide binding]; other site
990282009465	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
990282009466	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
990282009467	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282009468	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
990282009469	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
990282009470	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
990282009471	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282009472	active site
990282009473	phosphorylation site [posttranslational modification]
990282009474	intermolecular recognition site; other site
990282009475	dimerization interface [polypeptide binding]; other site
990282009476	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
990282009477	DNA binding site [nucleotide binding]
990282009478	sensor protein QseC; Provisional; Region: PRK10337
990282009479	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
990282009480	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282009481	dimer interface [polypeptide binding]; other site
990282009482	phosphorylation site [posttranslational modification]
990282009483	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282009484	ATP binding site [chemical binding]; other site
990282009485	Mg2+ binding site [ion binding]; other site
990282009486	G-X-G motif; other site
990282009487	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
990282009488	Uncharacterized conserved protein [Function unknown]; Region: COG1359
990282009489	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
990282009490	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282009491	ATP binding site [chemical binding]; other site
990282009492	Mg2+ binding site [ion binding]; other site
990282009493	G-X-G motif; other site
990282009494	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
990282009495	anchoring element; other site
990282009496	dimer interface [polypeptide binding]; other site
990282009497	ATP binding site [chemical binding]; other site
990282009498	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
990282009499	active site
990282009500	metal binding site [ion binding]; metal-binding site
990282009501	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
990282009502	esterase YqiA; Provisional; Region: PRK11071
990282009503	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
990282009504	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
990282009505	active site
990282009506	metal binding site [ion binding]; metal-binding site
990282009507	hexamer interface [polypeptide binding]; other site
990282009508	putative dehydrogenase; Provisional; Region: PRK11039
990282009509	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
990282009510	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
990282009511	dimer interface [polypeptide binding]; other site
990282009512	ADP-ribose binding site [chemical binding]; other site
990282009513	active site
990282009514	nudix motif; other site
990282009515	metal binding site [ion binding]; metal-binding site
990282009516	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
990282009517	hypothetical protein; Provisional; Region: PRK11653
990282009518	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
990282009519	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
990282009520	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
990282009521	putative active site [active]
990282009522	metal binding site [ion binding]; metal-binding site
990282009523	zinc transporter ZupT; Provisional; Region: PRK04201
990282009524	ZIP Zinc transporter; Region: Zip; pfam02535
990282009525	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
990282009526	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
990282009527	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
990282009528	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
990282009529	catalytic residues [active]
990282009530	hinge region; other site
990282009531	alpha helical domain; other site
990282009532	putative disulfide oxidoreductase; Provisional; Region: PRK04307
990282009533	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
990282009534	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
990282009535	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
990282009536	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
990282009537	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
990282009538	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
990282009539	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
990282009540	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
990282009541	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
990282009542	putative ribose interaction site [chemical binding]; other site
990282009543	putative ADP binding site [chemical binding]; other site
990282009544	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
990282009545	active site
990282009546	nucleotide binding site [chemical binding]; other site
990282009547	HIGH motif; other site
990282009548	KMSKS motif; other site
990282009549	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
990282009550	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
990282009551	metal binding triad; other site
990282009552	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
990282009553	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
990282009554	metal binding triad; other site
990282009555	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
990282009556	Uncharacterized conserved protein [Function unknown]; Region: COG3025
990282009557	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
990282009558	putative active site [active]
990282009559	putative metal binding residues [ion binding]; other site
990282009560	signature motif; other site
990282009561	putative triphosphate binding site [ion binding]; other site
990282009562	CHAD domain; Region: CHAD; pfam05235
990282009563	SH3 domain-containing protein; Provisional; Region: PRK10884
990282009564	Bacterial SH3 domain homologues; Region: SH3b; smart00287
990282009565	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
990282009566	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
990282009567	active site
990282009568	NTP binding site [chemical binding]; other site
990282009569	metal binding triad [ion binding]; metal-binding site
990282009570	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
990282009571	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
990282009572	Zn2+ binding site [ion binding]; other site
990282009573	Mg2+ binding site [ion binding]; other site
990282009574	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
990282009575	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
990282009576	homooctamer interface [polypeptide binding]; other site
990282009577	active site
990282009578	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
990282009579	UGMP family protein; Validated; Region: PRK09604
990282009580	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
990282009581	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
990282009582	DNA primase; Validated; Region: dnaG; PRK05667
990282009583	CHC2 zinc finger; Region: zf-CHC2; pfam01807
990282009584	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
990282009585	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
990282009586	active site
990282009587	metal binding site [ion binding]; metal-binding site
990282009588	interdomain interaction site; other site
990282009589	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
990282009590	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
990282009591	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
990282009592	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
990282009593	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
990282009594	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
990282009595	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
990282009596	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
990282009597	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
990282009598	DNA binding residues [nucleotide binding]
990282009599	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
990282009600	active site
990282009601	SUMO-1 interface [polypeptide binding]; other site
990282009602	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
990282009603	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
990282009604	FAD binding pocket [chemical binding]; other site
990282009605	FAD binding motif [chemical binding]; other site
990282009606	phosphate binding motif [ion binding]; other site
990282009607	NAD binding pocket [chemical binding]; other site
990282009608	Predicted transcriptional regulators [Transcription]; Region: COG1695
990282009609	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
990282009610	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
990282009611	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
990282009612	dimerization interface [polypeptide binding]; other site
990282009613	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
990282009614	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
990282009615	dimer interface [polypeptide binding]; other site
990282009616	putative CheW interface [polypeptide binding]; other site
990282009617	PAS fold; Region: PAS_3; pfam08447
990282009618	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
990282009619	putative active site [active]
990282009620	heme pocket [chemical binding]; other site
990282009621	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
990282009622	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
990282009623	dimer interface [polypeptide binding]; other site
990282009624	putative CheW interface [polypeptide binding]; other site
990282009625	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
990282009626	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
990282009627	inhibitor-cofactor binding pocket; inhibition site
990282009628	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282009629	catalytic residue [active]
990282009630	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
990282009631	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
990282009632	active site
990282009633	FMN binding site [chemical binding]; other site
990282009634	2,4-decadienoyl-CoA binding site; other site
990282009635	catalytic residue [active]
990282009636	4Fe-4S cluster binding site [ion binding]; other site
990282009637	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
990282009638	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
990282009639	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
990282009640	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282009641	S-adenosylmethionine binding site [chemical binding]; other site
990282009642	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
990282009643	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
990282009644	putative active site [active]
990282009645	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
990282009646	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
990282009647	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
990282009648	serine/threonine transporter SstT; Provisional; Region: PRK13628
990282009649	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
990282009650	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
990282009651	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
990282009652	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
990282009653	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
990282009654	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
990282009655	Predicted membrane protein [Function unknown]; Region: COG5393
990282009656	YqjK-like protein; Region: YqjK; pfam13997
990282009657	Predicted membrane protein [Function unknown]; Region: COG2259
990282009658	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
990282009659	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
990282009660	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
990282009661	putative dimer interface [polypeptide binding]; other site
990282009662	N-terminal domain interface [polypeptide binding]; other site
990282009663	putative substrate binding pocket (H-site) [chemical binding]; other site
990282009664	Predicted membrane protein [Function unknown]; Region: COG3152
990282009665	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282009666	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
990282009667	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
990282009668	dimerization interface [polypeptide binding]; other site
990282009669	Pirin-related protein [General function prediction only]; Region: COG1741
990282009670	Pirin; Region: Pirin; pfam02678
990282009671	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
990282009672	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
990282009673	serine transporter; Region: stp; TIGR00814
990282009674	L-serine dehydratase TdcG; Provisional; Region: PRK15040
990282009675	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
990282009676	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
990282009677	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
990282009678	Pyruvate formate lyase 1; Region: PFL1; cd01678
990282009679	coenzyme A binding site [chemical binding]; other site
990282009680	active site
990282009681	catalytic residues [active]
990282009682	glycine loop; other site
990282009683	propionate/acetate kinase; Provisional; Region: PRK12379
990282009684	Acetate kinase [Energy production and conversion]; Region: ackA; COG0282
990282009685	threonine/serine transporter TdcC; Provisional; Region: PRK13629
990282009686	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
990282009687	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
990282009688	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
990282009689	tetramer interface [polypeptide binding]; other site
990282009690	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282009691	catalytic residue [active]
990282009692	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
990282009693	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282009694	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
990282009695	putative substrate binding pocket [chemical binding]; other site
990282009696	putative dimerization interface [polypeptide binding]; other site
990282009697	glycerate kinase I; Provisional; Region: PRK10342
990282009698	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
990282009699	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
990282009700	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
990282009701	galactarate dehydratase; Region: galactar-dH20; TIGR03248
990282009702	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
990282009703	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
990282009704	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
990282009705	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
990282009706	substrate binding site [chemical binding]; other site
990282009707	ATP binding site [chemical binding]; other site
990282009708	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
990282009709	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
990282009710	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
990282009711	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
990282009712	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
990282009713	intersubunit interface [polypeptide binding]; other site
990282009714	active site
990282009715	zinc binding site [ion binding]; other site
990282009716	Na+ binding site [ion binding]; other site
990282009717	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
990282009718	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
990282009719	putative substrate binding site [chemical binding]; other site
990282009720	putative ATP binding site [chemical binding]; other site
990282009721	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
990282009722	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
990282009723	putative NAD(P) binding site [chemical binding]; other site
990282009724	catalytic Zn binding site [ion binding]; other site
990282009725	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
990282009726	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
990282009727	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
990282009728	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
990282009729	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
990282009730	putative SAM binding site [chemical binding]; other site
990282009731	putative homodimer interface [polypeptide binding]; other site
990282009732	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
990282009733	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
990282009734	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
990282009735	putative ligand binding site [chemical binding]; other site
990282009736	TIGR00252 family protein; Region: TIGR00252
990282009737	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
990282009738	dimer interface [polypeptide binding]; other site
990282009739	active site
990282009740	outer membrane lipoprotein; Provisional; Region: PRK11023
990282009741	BON domain; Region: BON; pfam04972
990282009742	BON domain; Region: BON; pfam04972
990282009743	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
990282009744	NADH(P)-binding; Region: NAD_binding_10; pfam13460
990282009745	NAD binding site [chemical binding]; other site
990282009746	active site
990282009747	intracellular protease, PfpI family; Region: PfpI; TIGR01382
990282009748	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
990282009749	proposed catalytic triad [active]
990282009750	conserved cys residue [active]
990282009751	hypothetical protein; Provisional; Region: PRK03467
990282009752	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
990282009753	GIY-YIG motif/motif A; other site
990282009754	putative active site [active]
990282009755	putative metal binding site [ion binding]; other site
990282009756	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
990282009757	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282009758	Coenzyme A binding pocket [chemical binding]; other site
990282009759	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
990282009760	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
990282009761	Peptidase family U32; Region: Peptidase_U32; pfam01136
990282009762	putative protease; Provisional; Region: PRK15447
990282009763	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
990282009764	hypothetical protein; Provisional; Region: PRK10508
990282009765	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
990282009766	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
990282009767	tryptophan permease; Provisional; Region: PRK10483
990282009768	aromatic amino acid transport protein; Region: araaP; TIGR00837
990282009769	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
990282009770	DEAD-like helicases superfamily; Region: DEXDc; smart00487
990282009771	ATP binding site [chemical binding]; other site
990282009772	Mg++ binding site [ion binding]; other site
990282009773	motif III; other site
990282009774	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
990282009775	nucleotide binding region [chemical binding]; other site
990282009776	ATP-binding site [chemical binding]; other site
990282009777	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
990282009778	putative RNA binding site [nucleotide binding]; other site
990282009779	lipoprotein NlpI; Provisional; Region: PRK11189
990282009780	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
990282009781	binding surface
990282009782	TPR motif; other site
990282009783	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
990282009784	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
990282009785	RNase E interface [polypeptide binding]; other site
990282009786	trimer interface [polypeptide binding]; other site
990282009787	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
990282009788	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
990282009789	RNase E interface [polypeptide binding]; other site
990282009790	trimer interface [polypeptide binding]; other site
990282009791	active site
990282009792	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
990282009793	putative nucleic acid binding region [nucleotide binding]; other site
990282009794	G-X-X-G motif; other site
990282009795	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
990282009796	RNA binding site [nucleotide binding]; other site
990282009797	domain interface; other site
990282009798	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
990282009799	16S/18S rRNA binding site [nucleotide binding]; other site
990282009800	S13e-L30e interaction site [polypeptide binding]; other site
990282009801	25S rRNA binding site [nucleotide binding]; other site
990282009802	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
990282009803	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
990282009804	RNA binding site [nucleotide binding]; other site
990282009805	active site
990282009806	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
990282009807	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
990282009808	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
990282009809	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
990282009810	translation initiation factor IF-2; Region: IF-2; TIGR00487
990282009811	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
990282009812	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
990282009813	G1 box; other site
990282009814	putative GEF interaction site [polypeptide binding]; other site
990282009815	GTP/Mg2+ binding site [chemical binding]; other site
990282009816	Switch I region; other site
990282009817	G2 box; other site
990282009818	G3 box; other site
990282009819	Switch II region; other site
990282009820	G4 box; other site
990282009821	G5 box; other site
990282009822	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
990282009823	Translation-initiation factor 2; Region: IF-2; pfam11987
990282009824	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
990282009825	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
990282009826	NusA N-terminal domain; Region: NusA_N; pfam08529
990282009827	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
990282009828	RNA binding site [nucleotide binding]; other site
990282009829	homodimer interface [polypeptide binding]; other site
990282009830	NusA-like KH domain; Region: KH_5; pfam13184
990282009831	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
990282009832	G-X-X-G motif; other site
990282009833	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
990282009834	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
990282009835	ribosome maturation protein RimP; Reviewed; Region: PRK00092
990282009836	hypothetical protein; Provisional; Region: PRK14641
990282009837	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
990282009838	putative oligomer interface [polypeptide binding]; other site
990282009839	putative RNA binding site [nucleotide binding]; other site
990282009840	argininosuccinate synthase; Validated; Region: PRK05370
990282009841	argininosuccinate synthase; Provisional; Region: PRK13820
990282009842	Domain of unknown function (DUF1963); Region: DUF1963; cl01600
990282009843	Preprotein translocase SecG subunit; Region: SecG; pfam03840
990282009844	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
990282009845	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
990282009846	active site
990282009847	substrate binding site [chemical binding]; other site
990282009848	metal binding site [ion binding]; metal-binding site
990282009849	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
990282009850	dihydropteroate synthase; Region: DHPS; TIGR01496
990282009851	substrate binding pocket [chemical binding]; other site
990282009852	dimer interface [polypeptide binding]; other site
990282009853	inhibitor binding site; inhibition site
990282009854	Transposase IS200 like; Region: Y1_Tnp; pfam01797
990282009855	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
990282009856	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282009857	Walker A motif; other site
990282009858	ATP binding site [chemical binding]; other site
990282009859	Walker B motif; other site
990282009860	arginine finger; other site
990282009861	Peptidase family M41; Region: Peptidase_M41; pfam01434
990282009862	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
990282009863	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282009864	S-adenosylmethionine binding site [chemical binding]; other site
990282009865	RNA-binding protein YhbY; Provisional; Region: PRK10343
990282009866	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
990282009867	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
990282009868	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
990282009869	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
990282009870	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
990282009871	GTPase CgtA; Reviewed; Region: obgE; PRK12298
990282009872	GTP1/OBG; Region: GTP1_OBG; pfam01018
990282009873	Obg GTPase; Region: Obg; cd01898
990282009874	G1 box; other site
990282009875	GTP/Mg2+ binding site [chemical binding]; other site
990282009876	Switch I region; other site
990282009877	G2 box; other site
990282009878	G3 box; other site
990282009879	Switch II region; other site
990282009880	G4 box; other site
990282009881	G5 box; other site
990282009882	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
990282009883	EamA-like transporter family; Region: EamA; pfam00892
990282009884	EamA-like transporter family; Region: EamA; pfam00892
990282009885	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
990282009886	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
990282009887	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
990282009888	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
990282009889	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
990282009890	substrate binding pocket [chemical binding]; other site
990282009891	chain length determination region; other site
990282009892	substrate-Mg2+ binding site; other site
990282009893	catalytic residues [active]
990282009894	aspartate-rich region 1; other site
990282009895	active site lid residues [active]
990282009896	aspartate-rich region 2; other site
990282009897	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
990282009898	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
990282009899	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
990282009900	hinge; other site
990282009901	active site
990282009902	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
990282009903	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
990282009904	anti sigma factor interaction site; other site
990282009905	regulatory phosphorylation site [posttranslational modification]; other site
990282009906	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
990282009907	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
990282009908	mce related protein; Region: MCE; pfam02470
990282009909	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
990282009910	conserved hypothetical integral membrane protein; Region: TIGR00056
990282009911	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
990282009912	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
990282009913	Walker A/P-loop; other site
990282009914	ATP binding site [chemical binding]; other site
990282009915	Q-loop/lid; other site
990282009916	ABC transporter signature motif; other site
990282009917	Walker B; other site
990282009918	D-loop; other site
990282009919	H-loop/switch region; other site
990282009920	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
990282009921	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
990282009922	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
990282009923	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
990282009924	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
990282009925	putative active site [active]
990282009926	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
990282009927	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
990282009928	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
990282009929	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
990282009930	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
990282009931	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
990282009932	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
990282009933	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
990282009934	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
990282009935	Walker A/P-loop; other site
990282009936	ATP binding site [chemical binding]; other site
990282009937	Q-loop/lid; other site
990282009938	ABC transporter signature motif; other site
990282009939	Walker B; other site
990282009940	D-loop; other site
990282009941	H-loop/switch region; other site
990282009942	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
990282009943	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
990282009944	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
990282009945	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
990282009946	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
990282009947	30S subunit binding site; other site
990282009948	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
990282009949	active site
990282009950	phosphorylation site [posttranslational modification]
990282009951	P-loop ATPase protein family; Region: ATP_bind_2; cl15794
990282009952	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
990282009953	dimerization domain swap beta strand [polypeptide binding]; other site
990282009954	regulatory protein interface [polypeptide binding]; other site
990282009955	active site
990282009956	regulatory phosphorylation site [posttranslational modification]; other site
990282009957	hypothetical protein; Provisional; Region: PRK10345
990282009958	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
990282009959	Transglycosylase; Region: Transgly; cl17702
990282009960	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
990282009961	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
990282009962	conserved cys residue [active]
990282009963	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
990282009964	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
990282009965	putative active site [active]
990282009966	heme pocket [chemical binding]; other site
990282009967	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282009968	dimer interface [polypeptide binding]; other site
990282009969	phosphorylation site [posttranslational modification]
990282009970	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282009971	ATP binding site [chemical binding]; other site
990282009972	Mg2+ binding site [ion binding]; other site
990282009973	G-X-G motif; other site
990282009974	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282009975	active site
990282009976	phosphorylation site [posttranslational modification]
990282009977	intermolecular recognition site; other site
990282009978	dimerization interface [polypeptide binding]; other site
990282009979	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
990282009980	putative binding surface; other site
990282009981	active site
990282009982	radical SAM protein, TIGR01212 family; Region: TIGR01212
990282009983	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282009984	FeS/SAM binding site; other site
990282009985	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
990282009986	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
990282009987	active site
990282009988	dimer interface [polypeptide binding]; other site
990282009989	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
990282009990	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
990282009991	active site
990282009992	FMN binding site [chemical binding]; other site
990282009993	substrate binding site [chemical binding]; other site
990282009994	3Fe-4S cluster binding site [ion binding]; other site
990282009995	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
990282009996	domain interface; other site
990282009997	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
990282009998	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
990282009999	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
990282010000	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
990282010001	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
990282010002	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
990282010003	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
990282010004	Na binding site [ion binding]; other site
990282010005	putative substrate binding site [chemical binding]; other site
990282010006	cytosine deaminase; Provisional; Region: PRK09230
990282010007	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
990282010008	active site
990282010009	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
990282010010	N-acetylmannosamine kinase; Provisional; Region: PRK05082
990282010011	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
990282010012	nucleotide binding site [chemical binding]; other site
990282010013	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
990282010014	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
990282010015	putative active site cavity [active]
990282010016	putative sialic acid transporter; Provisional; Region: PRK03893
990282010017	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282010018	putative substrate translocation pore; other site
990282010019	N-acetylneuraminate lyase; Provisional; Region: PRK04147
990282010020	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
990282010021	inhibitor site; inhibition site
990282010022	active site
990282010023	dimer interface [polypeptide binding]; other site
990282010024	catalytic residue [active]
990282010025	transcriptional regulator NanR; Provisional; Region: PRK03837
990282010026	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282010027	DNA-binding site [nucleotide binding]; DNA binding site
990282010028	FCD domain; Region: FCD; pfam07729
990282010029	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
990282010030	stringent starvation protein A; Provisional; Region: sspA; PRK09481
990282010031	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
990282010032	C-terminal domain interface [polypeptide binding]; other site
990282010033	putative GSH binding site (G-site) [chemical binding]; other site
990282010034	dimer interface [polypeptide binding]; other site
990282010035	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
990282010036	dimer interface [polypeptide binding]; other site
990282010037	N-terminal domain interface [polypeptide binding]; other site
990282010038	Family of unknown function (DUF695); Region: DUF695; pfam05117
990282010039	Protein of unknown function (DUF1260); Region: DUF1260; pfam06877
990282010040	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
990282010041	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
990282010042	23S rRNA interface [nucleotide binding]; other site
990282010043	L3 interface [polypeptide binding]; other site
990282010044	Predicted ATPase [General function prediction only]; Region: COG1485
990282010045	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
990282010046	hypothetical protein; Provisional; Region: PRK11677
990282010047	serine endoprotease; Provisional; Region: PRK10139
990282010048	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
990282010049	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
990282010050	protein binding site [polypeptide binding]; other site
990282010051	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
990282010052	serine endoprotease; Provisional; Region: PRK10898
990282010053	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
990282010054	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
990282010055	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
990282010056	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
990282010057	oxaloacetate decarboxylase; Provisional; Region: PRK14040
990282010058	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
990282010059	active site
990282010060	catalytic residues [active]
990282010061	metal binding site [ion binding]; metal-binding site
990282010062	homodimer binding site [polypeptide binding]; other site
990282010063	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
990282010064	carboxyltransferase (CT) interaction site; other site
990282010065	biotinylation site [posttranslational modification]; other site
990282010066	oxaloacetate decarboxylase subunit gamma; Provisional; Region: PRK02919
990282010067	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
990282010068	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
990282010069	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
990282010070	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
990282010071	transmembrane helices; other site
990282010072	Transcriptional regulators [Transcription]; Region: GntR; COG1802
990282010073	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282010074	DNA-binding site [nucleotide binding]; DNA binding site
990282010075	FCD domain; Region: FCD; pfam07729
990282010076	Transcriptional regulators [Transcription]; Region: GntR; COG1802
990282010077	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282010078	DNA-binding site [nucleotide binding]; DNA binding site
990282010079	malate dehydrogenase; Provisional; Region: PRK05086
990282010080	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
990282010081	NAD binding site [chemical binding]; other site
990282010082	dimerization interface [polypeptide binding]; other site
990282010083	Substrate binding site [chemical binding]; other site
990282010084	arginine repressor; Provisional; Region: PRK05066
990282010085	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
990282010086	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
990282010087	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
990282010088	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
990282010089	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
990282010090	RNAase interaction site [polypeptide binding]; other site
990282010091	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
990282010092	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
990282010093	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
990282010094	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
990282010095	HlyD family secretion protein; Region: HlyD_3; pfam13437
990282010096	efflux system membrane protein; Provisional; Region: PRK11594
990282010097	transcriptional regulator; Provisional; Region: PRK10632
990282010098	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282010099	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
990282010100	putative effector binding pocket; other site
990282010101	dimerization interface [polypeptide binding]; other site
990282010102	protease TldD; Provisional; Region: tldD; PRK10735
990282010103	hypothetical protein; Provisional; Region: PRK10899
990282010104	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
990282010105	ribonuclease G; Provisional; Region: PRK11712
990282010106	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
990282010107	homodimer interface [polypeptide binding]; other site
990282010108	oligonucleotide binding site [chemical binding]; other site
990282010109	Maf-like protein; Region: Maf; pfam02545
990282010110	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
990282010111	active site
990282010112	dimer interface [polypeptide binding]; other site
990282010113	rod shape-determining protein MreD; Provisional; Region: PRK11060
990282010114	rod shape-determining protein MreC; Region: mreC; TIGR00219
990282010115	rod shape-determining protein MreC; Region: MreC; pfam04085
990282010116	rod shape-determining protein MreB; Provisional; Region: PRK13927
990282010117	MreB and similar proteins; Region: MreB_like; cd10225
990282010118	nucleotide binding site [chemical binding]; other site
990282010119	Mg binding site [ion binding]; other site
990282010120	putative protofilament interaction site [polypeptide binding]; other site
990282010121	RodZ interaction site [polypeptide binding]; other site
990282010122	regulatory protein CsrD; Provisional; Region: PRK11059
990282010123	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
990282010124	metal binding site [ion binding]; metal-binding site
990282010125	active site
990282010126	I-site; other site
990282010127	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
990282010128	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
990282010129	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
990282010130	NADP binding site [chemical binding]; other site
990282010131	dimer interface [polypeptide binding]; other site
990282010132	TMAO/DMSO reductase; Reviewed; Region: PRK05363
990282010133	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
990282010134	Moco binding site; other site
990282010135	metal coordination site [ion binding]; other site
990282010136	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
990282010137	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
990282010138	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
990282010139	carboxyltransferase (CT) interaction site; other site
990282010140	biotinylation site [posttranslational modification]; other site
990282010141	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
990282010142	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
990282010143	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
990282010144	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
990282010145	hypothetical protein; Provisional; Region: PRK10633
990282010146	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
990282010147	Na binding site [ion binding]; other site
990282010148	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
990282010149	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
990282010150	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
990282010151	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
990282010152	FMN binding site [chemical binding]; other site
990282010153	active site
990282010154	catalytic residues [active]
990282010155	substrate binding site [chemical binding]; other site
990282010156	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
990282010157	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
990282010158	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
990282010159	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282010160	DNA methylase; Region: N6_N4_Mtase; pfam01555
990282010161	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
990282010162	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
990282010163	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
990282010164	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
990282010165	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
990282010166	metal binding site [ion binding]; metal-binding site
990282010167	active site
990282010168	I-site; other site
990282010169	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
990282010170	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
990282010171	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
990282010172	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
990282010173	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
990282010174	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
990282010175	HlyD family secretion protein; Region: HlyD_3; pfam13437
990282010176	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
990282010177	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
990282010178	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
990282010179	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
990282010180	trimer interface [polypeptide binding]; other site
990282010181	putative metal binding site [ion binding]; other site
990282010182	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
990282010183	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
990282010184	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
990282010185	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
990282010186	shikimate binding site; other site
990282010187	NAD(P) binding site [chemical binding]; other site
990282010188	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
990282010189	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
990282010190	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
990282010191	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
990282010192	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
990282010193	hypothetical protein; Validated; Region: PRK03430
990282010194	hypothetical protein; Provisional; Region: PRK10736
990282010195	DNA protecting protein DprA; Region: dprA; TIGR00732
990282010196	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
990282010197	active site
990282010198	catalytic residues [active]
990282010199	metal binding site [ion binding]; metal-binding site
990282010200	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
990282010201	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
990282010202	putative active site [active]
990282010203	substrate binding site [chemical binding]; other site
990282010204	putative cosubstrate binding site; other site
990282010205	catalytic site [active]
990282010206	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
990282010207	substrate binding site [chemical binding]; other site
990282010208	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
990282010209	putative RNA binding site [nucleotide binding]; other site
990282010210	16S rRNA methyltransferase B; Provisional; Region: PRK10901
990282010211	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282010212	S-adenosylmethionine binding site [chemical binding]; other site
990282010213	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
990282010214	TrkA-N domain; Region: TrkA_N; pfam02254
990282010215	TrkA-C domain; Region: TrkA_C; pfam02080
990282010216	TrkA-N domain; Region: TrkA_N; pfam02254
990282010217	TrkA-C domain; Region: TrkA_C; pfam02080
990282010218	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
990282010219	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
990282010220	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
990282010221	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
990282010222	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
990282010223	DNA binding residues [nucleotide binding]
990282010224	dimer interface [polypeptide binding]; other site
990282010225	metal binding site [ion binding]; metal-binding site
990282010226	hypothetical protein; Provisional; Region: PRK10203
990282010227	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
990282010228	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
990282010229	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
990282010230	alphaNTD homodimer interface [polypeptide binding]; other site
990282010231	alphaNTD - beta interaction site [polypeptide binding]; other site
990282010232	alphaNTD - beta' interaction site [polypeptide binding]; other site
990282010233	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
990282010234	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
990282010235	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
990282010236	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
990282010237	RNA binding surface [nucleotide binding]; other site
990282010238	30S ribosomal protein S11; Validated; Region: PRK05309
990282010239	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
990282010240	30S ribosomal protein S13; Region: bact_S13; TIGR03631
990282010241	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
990282010242	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
990282010243	SecY translocase; Region: SecY; pfam00344
990282010244	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
990282010245	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
990282010246	23S rRNA binding site [nucleotide binding]; other site
990282010247	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
990282010248	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
990282010249	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
990282010250	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
990282010251	23S rRNA interface [nucleotide binding]; other site
990282010252	5S rRNA interface [nucleotide binding]; other site
990282010253	L27 interface [polypeptide binding]; other site
990282010254	L5 interface [polypeptide binding]; other site
990282010255	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
990282010256	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
990282010257	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
990282010258	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
990282010259	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
990282010260	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
990282010261	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
990282010262	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
990282010263	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
990282010264	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
990282010265	RNA binding site [nucleotide binding]; other site
990282010266	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
990282010267	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
990282010268	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
990282010269	23S rRNA interface [nucleotide binding]; other site
990282010270	putative translocon interaction site; other site
990282010271	signal recognition particle (SRP54) interaction site; other site
990282010272	L23 interface [polypeptide binding]; other site
990282010273	trigger factor interaction site; other site
990282010274	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
990282010275	23S rRNA interface [nucleotide binding]; other site
990282010276	5S rRNA interface [nucleotide binding]; other site
990282010277	putative antibiotic binding site [chemical binding]; other site
990282010278	L25 interface [polypeptide binding]; other site
990282010279	L27 interface [polypeptide binding]; other site
990282010280	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
990282010281	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
990282010282	G-X-X-G motif; other site
990282010283	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
990282010284	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
990282010285	protein-rRNA interface [nucleotide binding]; other site
990282010286	putative translocon binding site; other site
990282010287	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
990282010288	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
990282010289	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
990282010290	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
990282010291	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
990282010292	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
990282010293	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
990282010294	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
990282010295	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
990282010296	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
990282010297	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
990282010298	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
990282010299	heme binding site [chemical binding]; other site
990282010300	ferroxidase pore; other site
990282010301	ferroxidase diiron center [ion binding]; other site
990282010302	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
990282010303	elongation factor Tu; Reviewed; Region: PRK00049
990282010304	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
990282010305	G1 box; other site
990282010306	GEF interaction site [polypeptide binding]; other site
990282010307	GTP/Mg2+ binding site [chemical binding]; other site
990282010308	Switch I region; other site
990282010309	G2 box; other site
990282010310	G3 box; other site
990282010311	Switch II region; other site
990282010312	G4 box; other site
990282010313	G5 box; other site
990282010314	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
990282010315	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
990282010316	Antibiotic Binding Site [chemical binding]; other site
990282010317	elongation factor G; Reviewed; Region: PRK00007
990282010318	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
990282010319	G1 box; other site
990282010320	putative GEF interaction site [polypeptide binding]; other site
990282010321	GTP/Mg2+ binding site [chemical binding]; other site
990282010322	Switch I region; other site
990282010323	G2 box; other site
990282010324	G3 box; other site
990282010325	Switch II region; other site
990282010326	G4 box; other site
990282010327	G5 box; other site
990282010328	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
990282010329	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
990282010330	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
990282010331	30S ribosomal protein S7; Validated; Region: PRK05302
990282010332	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
990282010333	S17 interaction site [polypeptide binding]; other site
990282010334	S8 interaction site; other site
990282010335	16S rRNA interaction site [nucleotide binding]; other site
990282010336	streptomycin interaction site [chemical binding]; other site
990282010337	23S rRNA interaction site [nucleotide binding]; other site
990282010338	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
990282010339	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
990282010340	sulfur relay protein TusC; Validated; Region: PRK00211
990282010341	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
990282010342	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
990282010343	YheO-like PAS domain; Region: PAS_6; pfam08348
990282010344	HTH domain; Region: HTH_22; pfam13309
990282010345	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
990282010346	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
990282010347	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
990282010348	phi X174 lysis protein; Provisional; Region: PRK02793
990282010349	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
990282010350	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
990282010351	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
990282010352	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
990282010353	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
990282010354	TrkA-N domain; Region: TrkA_N; pfam02254
990282010355	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
990282010356	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
990282010357	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282010358	Walker A/P-loop; other site
990282010359	ATP binding site [chemical binding]; other site
990282010360	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
990282010361	ABC transporter signature motif; other site
990282010362	Walker B; other site
990282010363	D-loop; other site
990282010364	ABC transporter; Region: ABC_tran_2; pfam12848
990282010365	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
990282010366	putative monooxygenase; Provisional; Region: PRK11118
990282010367	putative hydrolase; Provisional; Region: PRK10985
990282010368	SAM (Sterile alpha motif ); Region: SAM_superfamily; cl15755
990282010369	hypothetical protein; Provisional; Region: PRK04966
990282010370	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
990282010371	active site
990282010372	hypothetical protein; Provisional; Region: PRK10738
990282010373	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
990282010374	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
990282010375	ligand binding site [chemical binding]; other site
990282010376	flexible hinge region; other site
990282010377	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
990282010378	putative switch regulator; other site
990282010379	non-specific DNA interactions [nucleotide binding]; other site
990282010380	DNA binding site [nucleotide binding]
990282010381	sequence specific DNA binding site [nucleotide binding]; other site
990282010382	putative cAMP binding site [chemical binding]; other site
990282010383	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
990282010384	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
990282010385	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
990282010386	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
990282010387	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
990282010388	inhibitor-cofactor binding pocket; inhibition site
990282010389	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282010390	catalytic residue [active]
990282010391	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
990282010392	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
990282010393	glutamine binding [chemical binding]; other site
990282010394	catalytic triad [active]
990282010395	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
990282010396	cell filamentation protein Fic; Provisional; Region: PRK10347
990282010397	hypothetical protein; Provisional; Region: PRK10204
990282010398	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
990282010399	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
990282010400	substrate binding site [chemical binding]; other site
990282010401	putative transporter; Provisional; Region: PRK03699
990282010402	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282010403	putative substrate translocation pore; other site
990282010404	nitrite reductase subunit NirD; Provisional; Region: PRK14989
990282010405	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
990282010406	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
990282010407	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
990282010408	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
990282010409	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
990282010410	nitrite transporter NirC; Provisional; Region: PRK11562
990282010411	siroheme synthase; Provisional; Region: cysG; PRK10637
990282010412	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
990282010413	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
990282010414	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
990282010415	active site
990282010416	SAM binding site [chemical binding]; other site
990282010417	homodimer interface [polypeptide binding]; other site
990282010418	Autotransporter beta-domain; Region: Autotransporter; pfam03797
990282010419	Transposase IS200 like; Region: Y1_Tnp; pfam01797
990282010420	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
990282010421	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
990282010422	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
990282010423	active site
990282010424	HIGH motif; other site
990282010425	dimer interface [polypeptide binding]; other site
990282010426	KMSKS motif; other site
990282010427	phosphoglycolate phosphatase; Provisional; Region: PRK13222
990282010428	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282010429	motif II; other site
990282010430	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
990282010431	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
990282010432	substrate binding site [chemical binding]; other site
990282010433	hexamer interface [polypeptide binding]; other site
990282010434	metal binding site [ion binding]; metal-binding site
990282010435	DNA adenine methylase; Provisional; Region: PRK10904
990282010436	cell division protein DamX; Validated; Region: PRK10905
990282010437	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
990282010438	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
990282010439	active site
990282010440	dimer interface [polypeptide binding]; other site
990282010441	metal binding site [ion binding]; metal-binding site
990282010442	shikimate kinase; Reviewed; Region: aroK; PRK00131
990282010443	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
990282010444	ADP binding site [chemical binding]; other site
990282010445	magnesium binding site [ion binding]; other site
990282010446	putative shikimate binding site; other site
990282010447	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
990282010448	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
990282010449	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
990282010450	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
990282010451	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
990282010452	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
990282010453	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
990282010454	Transglycosylase; Region: Transgly; pfam00912
990282010455	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
990282010456	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
990282010457	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
990282010458	ADP-ribose binding site [chemical binding]; other site
990282010459	dimer interface [polypeptide binding]; other site
990282010460	active site
990282010461	nudix motif; other site
990282010462	metal binding site [ion binding]; metal-binding site
990282010463	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
990282010464	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
990282010465	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282010466	motif II; other site
990282010467	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
990282010468	RNA binding surface [nucleotide binding]; other site
990282010469	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
990282010470	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
990282010471	dimerization interface [polypeptide binding]; other site
990282010472	domain crossover interface; other site
990282010473	redox-dependent activation switch; other site
990282010474	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
990282010475	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
990282010476	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
990282010477	active site
990282010478	substrate-binding site [chemical binding]; other site
990282010479	metal-binding site [ion binding]
990282010480	ATP binding site [chemical binding]; other site
990282010481	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
990282010482	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
990282010483	dimerization interface [polypeptide binding]; other site
990282010484	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282010485	dimer interface [polypeptide binding]; other site
990282010486	phosphorylation site [posttranslational modification]
990282010487	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282010488	ATP binding site [chemical binding]; other site
990282010489	G-X-G motif; other site
990282010490	osmolarity response regulator; Provisional; Region: ompR; PRK09468
990282010491	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282010492	active site
990282010493	phosphorylation site [posttranslational modification]
990282010494	intermolecular recognition site; other site
990282010495	dimerization interface [polypeptide binding]; other site
990282010496	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
990282010497	DNA binding site [nucleotide binding]
990282010498	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
990282010499	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
990282010500	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
990282010501	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
990282010502	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
990282010503	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
990282010504	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
990282010505	RNA binding site [nucleotide binding]; other site
990282010506	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
990282010507	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
990282010508	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
990282010509	G1 box; other site
990282010510	GTP/Mg2+ binding site [chemical binding]; other site
990282010511	Switch I region; other site
990282010512	G2 box; other site
990282010513	G3 box; other site
990282010514	Switch II region; other site
990282010515	G4 box; other site
990282010516	G5 box; other site
990282010517	Nucleoside recognition; Region: Gate; pfam07670
990282010518	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
990282010519	Nucleoside recognition; Region: Gate; pfam07670
990282010520	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
990282010521	hypothetical protein; Provisional; Region: PRK09956
990282010522	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
990282010523	carboxylesterase BioH; Provisional; Region: PRK10349
990282010524	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
990282010525	DNA utilization protein GntX; Provisional; Region: PRK11595
990282010526	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
990282010527	active site
990282010528	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
990282010529	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
990282010530	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
990282010531	high-affinity gluconate transporter; Provisional; Region: PRK14984
990282010532	gluconate transporter; Region: gntP; TIGR00791
990282010533	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
990282010534	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
990282010535	maltodextrin phosphorylase; Provisional; Region: PRK14985
990282010536	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
990282010537	homodimer interface [polypeptide binding]; other site
990282010538	active site pocket [active]
990282010539	transcriptional regulator MalT; Provisional; Region: PRK04841
990282010540	AAA ATPase domain; Region: AAA_16; pfam13191
990282010541	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282010542	DNA binding residues [nucleotide binding]
990282010543	dimerization interface [polypeptide binding]; other site
990282010544	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
990282010545	DNA-damage-inducible protein J [DNA replication, recombination, and repair]; Region: RelB; COG3077
990282010546	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
990282010547	RNA 3' phosphate cyclase domain (class II). These proteins function as RNA cyclase to catalyze the ATP-dependent conversion of 3'-phosphate to a 2'.3'-cyclic phosphodiester at the end of RNA molecule. A conserved catalytic histidine...; Region: RNA_Cyclase_Class_II; cd00874
990282010548	putative active site [active]
990282010549	adenylation catalytic residue [active]
990282010550	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
990282010551	hypothetical protein; Reviewed; Region: PRK09588
990282010552	TROVE domain; Region: TROVE; pfam05731
990282010553	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
990282010554	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
990282010555	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282010556	Walker A motif; other site
990282010557	ATP binding site [chemical binding]; other site
990282010558	Walker B motif; other site
990282010559	arginine finger; other site
990282010560	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
990282010561	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
990282010562	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
990282010563	intramembrane serine protease GlpG; Provisional; Region: PRK10907
990282010564	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
990282010565	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
990282010566	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
990282010567	active site residue [active]
990282010568	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
990282010569	hypothetical protein; Provisional; Region: PRK09781
990282010570	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
990282010571	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
990282010572	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
990282010573	dimer interface [polypeptide binding]; other site
990282010574	active site
990282010575	metal binding site [ion binding]; metal-binding site
990282010576	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282010577	D-galactonate transporter; Region: 2A0114; TIGR00893
990282010578	putative substrate translocation pore; other site
990282010579	Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism / Carbohydrate transport and metabolism]; Region: IlvD; COG0129
990282010580	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
990282010581	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
990282010582	inhibitor site; inhibition site
990282010583	active site
990282010584	dimer interface [polypeptide binding]; other site
990282010585	catalytic residue [active]
990282010586	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
990282010587	Transcriptional regulator [Transcription]; Region: IclR; COG1414
990282010588	Bacterial transcriptional regulator; Region: IclR; pfam01614
990282010589	glycogen phosphorylase; Provisional; Region: PRK14986
990282010590	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
990282010591	homodimer interface [polypeptide binding]; other site
990282010592	active site pocket [active]
990282010593	glycogen synthase; Provisional; Region: glgA; PRK00654
990282010594	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
990282010595	ADP-binding pocket [chemical binding]; other site
990282010596	homodimer interface [polypeptide binding]; other site
990282010597	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
990282010598	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
990282010599	ligand binding site; other site
990282010600	oligomer interface; other site
990282010601	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
990282010602	dimer interface [polypeptide binding]; other site
990282010603	N-terminal domain interface [polypeptide binding]; other site
990282010604	sulfate 1 binding site; other site
990282010605	glycogen debranching enzyme; Provisional; Region: PRK03705
990282010606	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
990282010607	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
990282010608	active site
990282010609	catalytic site [active]
990282010610	glycogen branching enzyme; Provisional; Region: PRK05402
990282010611	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
990282010612	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
990282010613	active site
990282010614	catalytic site [active]
990282010615	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
990282010616	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
990282010617	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
990282010618	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
990282010619	low affinity gluconate transporter; Provisional; Region: PRK10472
990282010620	gluconate transporter; Region: gntP; TIGR00791
990282010621	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
990282010622	ATP-binding site [chemical binding]; other site
990282010623	Gluconate-6-phosphate binding site [chemical binding]; other site
990282010624	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
990282010625	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
990282010626	DNA binding site [nucleotide binding]
990282010627	domain linker motif; other site
990282010628	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
990282010629	putative ligand binding site [chemical binding]; other site
990282010630	putative dimerization interface [polypeptide binding]; other site
990282010631	Pirin-related protein [General function prediction only]; Region: COG1741
990282010632	Pirin; Region: Pirin; pfam02678
990282010633	putative oxidoreductase; Provisional; Region: PRK10206
990282010634	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
990282010635	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
990282010636	putative acetyltransferase YhhY; Provisional; Region: PRK10140
990282010637	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282010638	Coenzyme A binding pocket [chemical binding]; other site
990282010639	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
990282010640	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
990282010641	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
990282010642	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
990282010643	substrate binding site [chemical binding]; other site
990282010644	dimer interface [polypeptide binding]; other site
990282010645	ATP binding site [chemical binding]; other site
990282010646	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
990282010647	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
990282010648	Protein of unknown function, DUF606; Region: DUF606; pfam04657
990282010649	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
990282010650	active site
990282010651	substrate binding pocket [chemical binding]; other site
990282010652	homodimer interaction site [polypeptide binding]; other site
990282010653	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
990282010654	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
990282010655	hypothetical protein; Provisional; Region: PRK10350
990282010656	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
990282010657	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
990282010658	putative active site [active]
990282010659	catalytic site [active]
990282010660	putative metal binding site [ion binding]; other site
990282010661	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
990282010662	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
990282010663	Walker A/P-loop; other site
990282010664	ATP binding site [chemical binding]; other site
990282010665	Q-loop/lid; other site
990282010666	ABC transporter signature motif; other site
990282010667	Walker B; other site
990282010668	D-loop; other site
990282010669	H-loop/switch region; other site
990282010670	TOBE domain; Region: TOBE_2; pfam08402
990282010671	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
990282010672	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282010673	dimer interface [polypeptide binding]; other site
990282010674	conserved gate region; other site
990282010675	ABC-ATPase subunit interface; other site
990282010676	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
990282010677	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282010678	dimer interface [polypeptide binding]; other site
990282010679	conserved gate region; other site
990282010680	putative PBP binding loops; other site
990282010681	ABC-ATPase subunit interface; other site
990282010682	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
990282010683	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
990282010684	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
990282010685	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
990282010686	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
990282010687	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
990282010688	Walker A/P-loop; other site
990282010689	ATP binding site [chemical binding]; other site
990282010690	Q-loop/lid; other site
990282010691	ABC transporter signature motif; other site
990282010692	Walker B; other site
990282010693	D-loop; other site
990282010694	H-loop/switch region; other site
990282010695	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
990282010696	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
990282010697	Walker A/P-loop; other site
990282010698	ATP binding site [chemical binding]; other site
990282010699	Q-loop/lid; other site
990282010700	ABC transporter signature motif; other site
990282010701	Walker B; other site
990282010702	D-loop; other site
990282010703	H-loop/switch region; other site
990282010704	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
990282010705	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
990282010706	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
990282010707	TM-ABC transporter signature motif; other site
990282010708	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
990282010709	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
990282010710	TM-ABC transporter signature motif; other site
990282010711	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
990282010712	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
990282010713	dimerization interface [polypeptide binding]; other site
990282010714	ligand binding site [chemical binding]; other site
990282010715	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
990282010716	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
990282010717	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
990282010718	dimerization interface [polypeptide binding]; other site
990282010719	ligand binding site [chemical binding]; other site
990282010720	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
990282010721	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
990282010722	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
990282010723	DNA binding residues [nucleotide binding]
990282010724	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
990282010725	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
990282010726	cell division protein FtsE; Provisional; Region: PRK10908
990282010727	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282010728	Walker A/P-loop; other site
990282010729	ATP binding site [chemical binding]; other site
990282010730	Q-loop/lid; other site
990282010731	ABC transporter signature motif; other site
990282010732	Walker B; other site
990282010733	D-loop; other site
990282010734	H-loop/switch region; other site
990282010735	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
990282010736	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
990282010737	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
990282010738	P loop; other site
990282010739	GTP binding site [chemical binding]; other site
990282010740	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
990282010741	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282010742	S-adenosylmethionine binding site [chemical binding]; other site
990282010743	hypothetical protein; Provisional; Region: PRK10910
990282010744	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
990282010745	Predicted membrane protein [Function unknown]; Region: COG3714
990282010746	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
990282010747	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
990282010748	metal-binding site [ion binding]
990282010749	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
990282010750	Soluble P-type ATPase [General function prediction only]; Region: COG4087
990282010751	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
990282010752	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
990282010753	dimer interface [polypeptide binding]; other site
990282010754	ligand binding site [chemical binding]; other site
990282010755	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
990282010756	dimerization interface [polypeptide binding]; other site
990282010757	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
990282010758	dimer interface [polypeptide binding]; other site
990282010759	putative CheW interface [polypeptide binding]; other site
990282010760	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
990282010761	CPxP  motif; other site
990282010762	hypothetical protein; Provisional; Region: PRK11212
990282010763	hypothetical protein; Provisional; Region: PRK11615
990282010764	major facilitator superfamily transporter; Provisional; Region: PRK05122
990282010765	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282010766	putative substrate translocation pore; other site
990282010767	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
990282010768	Domain of unknown function DUF20; Region: UPF0118; pfam01594
990282010769	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
990282010770	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
990282010771	nickel responsive regulator; Provisional; Region: PRK02967
990282010772	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
990282010773	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
990282010774	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
990282010775	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
990282010776	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
990282010777	Walker A/P-loop; other site
990282010778	ATP binding site [chemical binding]; other site
990282010779	Q-loop/lid; other site
990282010780	ABC transporter signature motif; other site
990282010781	Walker B; other site
990282010782	D-loop; other site
990282010783	H-loop/switch region; other site
990282010784	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
990282010785	Walker A/P-loop; other site
990282010786	ATP binding site [chemical binding]; other site
990282010787	Q-loop/lid; other site
990282010788	ABC transporter signature motif; other site
990282010789	Walker B; other site
990282010790	D-loop; other site
990282010791	H-loop/switch region; other site
990282010792	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
990282010793	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
990282010794	HlyD family secretion protein; Region: HlyD; pfam00529
990282010795	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
990282010796	HlyD family secretion protein; Region: HlyD_3; pfam13437
990282010797	Predicted flavoproteins [General function prediction only]; Region: COG2081
990282010798	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
990282010799	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
990282010800	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
990282010801	universal stress protein UspB; Provisional; Region: PRK04960
990282010802	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
990282010803	Ligand Binding Site [chemical binding]; other site
990282010804	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
990282010805	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282010806	putative substrate translocation pore; other site
990282010807	POT family; Region: PTR2; pfam00854
990282010808	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282010809	S-adenosylmethionine binding site [chemical binding]; other site
990282010810	oligopeptidase A; Provisional; Region: PRK10911
990282010811	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
990282010812	active site
990282010813	Zn binding site [ion binding]; other site
990282010814	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
990282010815	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
990282010816	active site
990282010817	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
990282010818	glutathione reductase; Validated; Region: PRK06116
990282010819	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
990282010820	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
990282010821	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
990282010822	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
990282010823	active site
990282010824	homodimer interface [polypeptide binding]; other site
990282010825	homotetramer interface [polypeptide binding]; other site
990282010826	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
990282010827	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
990282010828	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
990282010829	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
990282010830	substrate binding site [chemical binding]; other site
990282010831	ATP binding site [chemical binding]; other site
990282010832	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
990282010833	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
990282010834	putative active site [active]
990282010835	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
990282010836	dimer interface [polypeptide binding]; other site
990282010837	active site
990282010838	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
990282010839	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282010840	DNA-binding site [nucleotide binding]; DNA binding site
990282010841	UTRA domain; Region: UTRA; pfam07702
990282010842	trehalase; Provisional; Region: treF; PRK13270
990282010843	Trehalase; Region: Trehalase; pfam01204
990282010844	Phage-related lysozyme (muraminidase) [General function prediction only]; Region: COG3772
990282010845	catalytic residue [active]
990282010846	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
990282010847	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282010848	DNA binding residues [nucleotide binding]
990282010849	dimerization interface [polypeptide binding]; other site
990282010850	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282010851	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282010852	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
990282010853	putative effector binding pocket; other site
990282010854	putative dimerization interface [polypeptide binding]; other site
990282010855	inner membrane protein YhjD; Region: TIGR00766
990282010856	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282010857	metabolite-proton symporter; Region: 2A0106; TIGR00883
990282010858	putative substrate translocation pore; other site
990282010859	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
990282010860	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
990282010861	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
990282010862	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
990282010863	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
990282010864	substrate binding site [chemical binding]; other site
990282010865	ATP binding site [chemical binding]; other site
990282010866	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
990282010867	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
990282010868	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
990282010869	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
990282010870	putative diguanylate cyclase; Provisional; Region: PRK13561
990282010871	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
990282010872	metal binding site [ion binding]; metal-binding site
990282010873	active site
990282010874	I-site; other site
990282010875	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
990282010876	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
990282010877	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
990282010878	TPR motif; other site
990282010879	binding surface
990282010880	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
990282010881	TPR motif; other site
990282010882	binding surface
990282010883	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
990282010884	binding surface
990282010885	TPR motif; other site
990282010886	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
990282010887	endo-1,4-D-glucanase; Provisional; Region: PRK11097
990282010888	cellulose synthase regulator protein; Provisional; Region: PRK11114
990282010889	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
990282010890	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
990282010891	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
990282010892	DXD motif; other site
990282010893	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
990282010894	PilZ domain; Region: PilZ; pfam07238
990282010895	cell division protein; Provisional; Region: PRK10037
990282010896	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
990282010897	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
990282010898	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
990282010899	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
990282010900	cellulose synthase operon protein YhjU; Region: cellulose_yhjU; TIGR03368
990282010901	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
990282010902	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
990282010903	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
990282010904	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
990282010905	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
990282010906	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
990282010907	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
990282010908	Walker A/P-loop; other site
990282010909	ATP binding site [chemical binding]; other site
990282010910	Q-loop/lid; other site
990282010911	ABC transporter signature motif; other site
990282010912	Walker B; other site
990282010913	D-loop; other site
990282010914	H-loop/switch region; other site
990282010915	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
990282010916	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
990282010917	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
990282010918	Walker A/P-loop; other site
990282010919	ATP binding site [chemical binding]; other site
990282010920	Q-loop/lid; other site
990282010921	ABC transporter signature motif; other site
990282010922	Walker B; other site
990282010923	D-loop; other site
990282010924	H-loop/switch region; other site
990282010925	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
990282010926	dipeptide transporter; Provisional; Region: PRK10913
990282010927	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
990282010928	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282010929	dimer interface [polypeptide binding]; other site
990282010930	conserved gate region; other site
990282010931	putative PBP binding loops; other site
990282010932	ABC-ATPase subunit interface; other site
990282010933	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
990282010934	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282010935	dimer interface [polypeptide binding]; other site
990282010936	conserved gate region; other site
990282010937	putative PBP binding loops; other site
990282010938	ABC-ATPase subunit interface; other site
990282010939	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
990282010940	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
990282010941	peptide binding site [polypeptide binding]; other site
990282010942	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
990282010943	Arylsulfotransferase (ASST); Region: Arylsulfotran_2; pfam14269
990282010944	Transcriptional regulators [Transcription]; Region: PurR; COG1609
990282010945	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
990282010946	DNA binding site [nucleotide binding]
990282010947	domain linker motif; other site
990282010948	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_8; cd06287
990282010949	putative dimerization interface [polypeptide binding]; other site
990282010950	putative ligand binding site [chemical binding]; other site
990282010951	phosphoethanolamine transferase; Provisional; Region: PRK11560
990282010952	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
990282010953	Sulfatase; Region: Sulfatase; pfam00884
990282010954	long polar fimbrial protein LpfE; Provisional; Region: PRK15205
990282010955	long polar fimbrial outer membrane usher protein LpfC; Provisional; Region: PRK15207
990282010956	PapC N-terminal domain; Region: PapC_N; pfam13954
990282010957	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
990282010958	PapC C-terminal domain; Region: PapC_C; pfam13953
990282010959	long polar fimbrial chaperone LpfB; Provisional; Region: PRK15208
990282010960	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
990282010961	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
990282010962	long polar fimbrial protein LpfA; Provisional; Region: PRK15209
990282010963	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
990282010964	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
990282010965	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282010966	Coenzyme A binding pocket [chemical binding]; other site
990282010967	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
990282010968	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
990282010969	molybdopterin cofactor binding site [chemical binding]; other site
990282010970	substrate binding site [chemical binding]; other site
990282010971	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
990282010972	molybdopterin cofactor binding site; other site
990282010973	putative outer membrane lipoprotein; Provisional; Region: PRK10510
990282010974	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
990282010975	ligand binding site [chemical binding]; other site
990282010976	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
990282010977	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
990282010978	dimerization interface [polypeptide binding]; other site
990282010979	ligand binding site [chemical binding]; other site
990282010980	NADP binding site [chemical binding]; other site
990282010981	catalytic site [active]
990282010982	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
990282010983	Predicted transcriptional regulator [Transcription]; Region: COG2944
990282010984	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
990282010985	salt bridge; other site
990282010986	non-specific DNA binding site [nucleotide binding]; other site
990282010987	sequence-specific DNA binding site [nucleotide binding]; other site
990282010988	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
990282010989	DNA-binding site [nucleotide binding]; DNA binding site
990282010990	RNA-binding motif; other site
990282010991	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
990282010992	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
990282010993	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
990282010994	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282010995	Coenzyme A binding pocket [chemical binding]; other site
990282010996	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
990282010997	DALR anticodon binding domain; Region: DALR_1; pfam05746
990282010998	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
990282010999	dimer interface [polypeptide binding]; other site
990282011000	motif 1; other site
990282011001	active site
990282011002	motif 2; other site
990282011003	motif 3; other site
990282011004	YsaB-like lipoprotein; Region: YsaB; pfam13983
990282011005	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
990282011006	Acyltransferase family; Region: Acyl_transf_3; pfam01757
990282011007	Predicted membrane protein [Function unknown]; Region: COG4682
990282011008	yiaA/B two helix domain; Region: YiaAB; cl01759
990282011009	yiaA/B two helix domain; Region: YiaAB; cl01759
990282011010	xylulokinase; Provisional; Region: PRK15027
990282011011	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
990282011012	N- and C-terminal domain interface [polypeptide binding]; other site
990282011013	active site
990282011014	MgATP binding site [chemical binding]; other site
990282011015	catalytic site [active]
990282011016	metal binding site [ion binding]; metal-binding site
990282011017	xylulose binding site [chemical binding]; other site
990282011018	homodimer interface [polypeptide binding]; other site
990282011019	xylose isomerase; Provisional; Region: PRK05474
990282011020	xylose isomerase; Region: xylose_isom_A; TIGR02630
990282011021	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
990282011022	putative dimerization interface [polypeptide binding]; other site
990282011023	Transcriptional regulators [Transcription]; Region: PurR; COG1609
990282011024	putative ligand binding site [chemical binding]; other site
990282011025	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282011026	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
990282011027	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282011028	hypothetical protein; Provisional; Region: PRK10356
990282011029	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
990282011030	alpha-amylase; Reviewed; Region: malS; PRK09505
990282011031	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
990282011032	active site
990282011033	catalytic site [active]
990282011034	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
990282011035	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
990282011036	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282011037	homodimer interface [polypeptide binding]; other site
990282011038	catalytic residue [active]
990282011039	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
990282011040	Transcriptional regulator [Transcription]; Region: IclR; COG1414
990282011041	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
990282011042	Bacterial transcriptional regulator; Region: IclR; pfam01614
990282011043	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
990282011044	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
990282011045	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
990282011046	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
990282011047	DctM-like transporters; Region: DctM; pfam06808
990282011048	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
990282011049	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
990282011050	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
990282011051	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
990282011052	putative N- and C-terminal domain interface [polypeptide binding]; other site
990282011053	putative active site [active]
990282011054	MgATP binding site [chemical binding]; other site
990282011055	catalytic site [active]
990282011056	metal binding site [ion binding]; metal-binding site
990282011057	putative xylulose binding site [chemical binding]; other site
990282011058	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
990282011059	active site
990282011060	dimer interface [polypeptide binding]; other site
990282011061	magnesium binding site [ion binding]; other site
990282011062	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
990282011063	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
990282011064	AP (apurinic/apyrimidinic) site pocket; other site
990282011065	DNA interaction; other site
990282011066	Metal-binding active site; metal-binding site
990282011067	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
990282011068	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
990282011069	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282011070	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
990282011071	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
990282011072	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
990282011073	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
990282011074	NAD(P) binding site [chemical binding]; other site
990282011075	catalytic residues [active]
990282011076	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
990282011077	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
990282011078	nucleotide binding site [chemical binding]; other site
990282011079	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
990282011080	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
990282011081	G1 box; other site
990282011082	putative GEF interaction site [polypeptide binding]; other site
990282011083	GTP/Mg2+ binding site [chemical binding]; other site
990282011084	Switch I region; other site
990282011085	G2 box; other site
990282011086	G3 box; other site
990282011087	Switch II region; other site
990282011088	G4 box; other site
990282011089	G5 box; other site
990282011090	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
990282011091	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
990282011092	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
990282011093	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
990282011094	selenocysteine synthase; Provisional; Region: PRK04311
990282011095	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
990282011096	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
990282011097	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
990282011098	catalytic residue [active]
990282011099	putative glutathione S-transferase; Provisional; Region: PRK10357
990282011100	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
990282011101	putative C-terminal domain interface [polypeptide binding]; other site
990282011102	putative GSH binding site (G-site) [chemical binding]; other site
990282011103	putative dimer interface [polypeptide binding]; other site
990282011104	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
990282011105	dimer interface [polypeptide binding]; other site
990282011106	N-terminal domain interface [polypeptide binding]; other site
990282011107	putative substrate binding pocket (H-site) [chemical binding]; other site
990282011108	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
990282011109	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
990282011110	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
990282011111	active site
990282011112	P-loop; other site
990282011113	phosphorylation site [posttranslational modification]
990282011114	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
990282011115	active site
990282011116	phosphorylation site [posttranslational modification]
990282011117	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
990282011118	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
990282011119	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
990282011120	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
990282011121	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
990282011122	hypothetical protein; Provisional; Region: PRK11020
990282011123	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
990282011124	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
990282011125	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
990282011126	trimer interface [polypeptide binding]; other site
990282011127	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
990282011128	Haemagglutinin; Region: HIM; pfam05662
990282011129	Haemagglutinin; Region: HIM; pfam05662
990282011130	YadA-like C-terminal region; Region: YadA; pfam03895
990282011131	L-lactate permease; Provisional; Region: PRK10420
990282011132	glycolate transporter; Provisional; Region: PRK09695
990282011133	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
990282011134	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282011135	DNA-binding site [nucleotide binding]; DNA binding site
990282011136	FCD domain; Region: FCD; pfam07729
990282011137	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
990282011138	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
990282011139	active site
990282011140	substrate binding site [chemical binding]; other site
990282011141	FMN binding site [chemical binding]; other site
990282011142	putative catalytic residues [active]
990282011143	putative rRNA methylase; Provisional; Region: PRK10358
990282011144	Transcriptional regulators [Transcription]; Region: PurR; COG1609
990282011145	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
990282011146	DNA binding site [nucleotide binding]
990282011147	domain linker motif; other site
990282011148	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
990282011149	putative dimerization interface [polypeptide binding]; other site
990282011150	putative ligand binding site [chemical binding]; other site
990282011151	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
990282011152	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
990282011153	active site pocket [active]
990282011154	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282011155	D-galactonate transporter; Region: 2A0114; TIGR00893
990282011156	putative substrate translocation pore; other site
990282011157	serine acetyltransferase; Provisional; Region: cysE; PRK11132
990282011158	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
990282011159	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
990282011160	trimer interface [polypeptide binding]; other site
990282011161	active site
990282011162	substrate binding site [chemical binding]; other site
990282011163	CoA binding site [chemical binding]; other site
990282011164	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
990282011165	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
990282011166	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
990282011167	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
990282011168	SecA binding site; other site
990282011169	Preprotein binding site; other site
990282011170	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
990282011171	GSH binding site [chemical binding]; other site
990282011172	catalytic residues [active]
990282011173	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
990282011174	active site residue [active]
990282011175	phosphoglyceromutase; Provisional; Region: PRK05434
990282011176	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
990282011177	AmiB activator; Provisional; Region: PRK11637
990282011178	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
990282011179	Peptidase family M23; Region: Peptidase_M23; pfam01551
990282011180	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
990282011181	NodB motif; other site
990282011182	putative active site [active]
990282011183	putative catalytic site [active]
990282011184	Zn binding site [ion binding]; other site
990282011185	putative glycosyl transferase; Provisional; Region: PRK10073
990282011186	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
990282011187	active site
990282011188	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
990282011189	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
990282011190	NAD(P) binding site [chemical binding]; other site
990282011191	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
990282011192	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
990282011193	substrate-cofactor binding pocket; other site
990282011194	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282011195	catalytic residue [active]
990282011196	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
990282011197	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
990282011198	NADP binding site [chemical binding]; other site
990282011199	homopentamer interface [polypeptide binding]; other site
990282011200	substrate binding site [chemical binding]; other site
990282011201	active site
990282011202	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
990282011203	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
990282011204	putative active site [active]
990282011205	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
990282011206	Glycosyltransferase family 9 (heptosyltransferase); Region: Glyco_transf_9; pfam01075
990282011207	putative active site [active]
990282011208	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
990282011209	O-antigen ligase RfaL; Provisional; Region: PRK15487
990282011210	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
990282011211	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
990282011212	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
990282011213	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
990282011214	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
990282011215	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
990282011216	Ligand binding site; other site
990282011217	metal-binding site
990282011218	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
990282011219	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
990282011220	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
990282011221	Ligand binding site; other site
990282011222	metal-binding site
990282011223	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
990282011224	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
990282011225	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
990282011226	putative ADP-binding pocket [chemical binding]; other site
990282011227	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
990282011228	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
990282011229	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
990282011230	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
990282011231	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
990282011232	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
990282011233	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
990282011234	putative active site [active]
990282011235	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
990282011236	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
990282011237	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
990282011238	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
990282011239	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
990282011240	active site
990282011241	(T/H)XGH motif; other site
990282011242	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
990282011243	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
990282011244	DNA binding site [nucleotide binding]
990282011245	catalytic residue [active]
990282011246	H2TH interface [polypeptide binding]; other site
990282011247	putative catalytic residues [active]
990282011248	turnover-facilitating residue; other site
990282011249	intercalation triad [nucleotide binding]; other site
990282011250	8OG recognition residue [nucleotide binding]; other site
990282011251	putative reading head residues; other site
990282011252	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
990282011253	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
990282011254	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
990282011255	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
990282011256	hypothetical protein; Reviewed; Region: PRK00024
990282011257	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
990282011258	MPN+ (JAMM) motif; other site
990282011259	Zinc-binding site [ion binding]; other site
990282011260	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
990282011261	Flavoprotein; Region: Flavoprotein; pfam02441
990282011262	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
990282011263	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
990282011264	trimer interface [polypeptide binding]; other site
990282011265	active site
990282011266	division inhibitor protein; Provisional; Region: slmA; PRK09480
990282011267	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
990282011268	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
990282011269	active site
990282011270	ribonuclease PH; Reviewed; Region: rph; PRK00173
990282011271	Ribonuclease PH; Region: RNase_PH_bact; cd11362
990282011272	hexamer interface [polypeptide binding]; other site
990282011273	active site
990282011274	hypothetical protein; Provisional; Region: PRK11820
990282011275	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
990282011276	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
990282011277	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282011278	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282011279	dimerization interface [polypeptide binding]; other site
990282011280	LysR substrate binding domain; Region: LysR_substrate; pfam03466
990282011281	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
990282011282	Predicted membrane protein [Function unknown]; Region: COG2860
990282011283	UPF0126 domain; Region: UPF0126; pfam03458
990282011284	UPF0126 domain; Region: UPF0126; pfam03458
990282011285	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
990282011286	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
990282011287	nucleotide binding pocket [chemical binding]; other site
990282011288	K-X-D-G motif; other site
990282011289	catalytic site [active]
990282011290	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
990282011291	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
990282011292	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
990282011293	catalytic site [active]
990282011294	G-X2-G-X-G-K; other site
990282011295	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
990282011296	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
990282011297	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
990282011298	Zn2+ binding site [ion binding]; other site
990282011299	Mg2+ binding site [ion binding]; other site
990282011300	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
990282011301	synthetase active site [active]
990282011302	NTP binding site [chemical binding]; other site
990282011303	metal binding site [ion binding]; metal-binding site
990282011304	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
990282011305	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
990282011306	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
990282011307	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
990282011308	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
990282011309	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
990282011310	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
990282011311	generic binding surface II; other site
990282011312	ssDNA binding site; other site
990282011313	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
990282011314	ATP binding site [chemical binding]; other site
990282011315	putative Mg++ binding site [ion binding]; other site
990282011316	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
990282011317	nucleotide binding region [chemical binding]; other site
990282011318	ATP-binding site [chemical binding]; other site
990282011319	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
990282011320	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
990282011321	AsmA family; Region: AsmA; pfam05170
990282011322	putative alpha-glucosidase; Provisional; Region: PRK10658
990282011323	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
990282011324	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
990282011325	active site
990282011326	homotrimer interface [polypeptide binding]; other site
990282011327	catalytic site [active]
990282011328	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
990282011329	putative transporter; Provisional; Region: PRK11462
990282011330	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
990282011331	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282011332	AAA domain; Region: AAA_23; pfam13476
990282011333	Walker A/P-loop; other site
990282011334	ATP binding site [chemical binding]; other site
990282011335	AAA domain; Region: AAA_21; pfam13304
990282011336	Methyltransferase domain; Region: Methyltransf_27; pfam13708
990282011337	Virulence protein [General function prediction only]; Region: COG3943
990282011338	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
990282011339	autotransport protein MisL; Provisional; Region: PRK15313
990282011340	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
990282011341	Autotransporter beta-domain; Region: Autotransporter; pfam03797
990282011342	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
990282011343	DNA binding site [nucleotide binding]
990282011344	Isochorismatase family; Region: Isochorismatase; pfam00857
990282011345	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
990282011346	catalytic triad [active]
990282011347	dimer interface [polypeptide binding]; other site
990282011348	conserved cis-peptide bond; other site
990282011349	magnesium-transporting ATPase; Provisional; Region: PRK15122
990282011350	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
990282011351	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
990282011352	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
990282011353	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282011354	motif II; other site
990282011355	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
990282011356	magnesium transport protein MgtC; Provisional; Region: PRK15385
990282011357	MgtC family; Region: MgtC; pfam02308
990282011358	EamA-like transporter family; Region: EamA; pfam00892
990282011359	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
990282011360	EamA-like transporter family; Region: EamA; pfam00892
990282011361	hypothetical protein; Provisional; Region: PRK09956
990282011362	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
990282011363	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
990282011364	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
990282011365	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
990282011366	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
990282011367	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
990282011368	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
990282011369	active site
990282011370	phosphorylation site [posttranslational modification]
990282011371	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
990282011372	active pocket/dimerization site; other site
990282011373	active site
990282011374	phosphorylation site [posttranslational modification]
990282011375	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
990282011376	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282011377	Walker A motif; other site
990282011378	ATP binding site [chemical binding]; other site
990282011379	Walker B motif; other site
990282011380	arginine finger; other site
990282011381	Transcriptional antiterminator [Transcription]; Region: COG3933
990282011382	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
990282011383	active site
990282011384	active pocket/dimerization site; other site
990282011385	phosphorylation site [posttranslational modification]
990282011386	PRD domain; Region: PRD; pfam00874
990282011387	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
990282011388	beta-galactosidase; Region: BGL; TIGR03356
990282011389	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
990282011390	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282011391	putative substrate translocation pore; other site
990282011392	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4737
990282011393	Predicted transcriptional regulator [Transcription]; Region: COG2944
990282011394	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
990282011395	non-specific DNA binding site [nucleotide binding]; other site
990282011396	salt bridge; other site
990282011397	sequence-specific DNA binding site [nucleotide binding]; other site
990282011398	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
990282011399	dimerization domain swap beta strand [polypeptide binding]; other site
990282011400	regulatory protein interface [polypeptide binding]; other site
990282011401	active site
990282011402	regulatory phosphorylation site [posttranslational modification]; other site
990282011403	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
990282011404	intersubunit interface [polypeptide binding]; other site
990282011405	active site
990282011406	zinc binding site [ion binding]; other site
990282011407	Na+ binding site [ion binding]; other site
990282011408	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
990282011409	uncharacterized subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_1; cd07774
990282011410	putative N- and C-terminal domain interface [polypeptide binding]; other site
990282011411	putative active site [active]
990282011412	putative MgATP binding site [chemical binding]; other site
990282011413	catalytic site [active]
990282011414	metal binding site [ion binding]; metal-binding site
990282011415	putative carbohydrate binding site [chemical binding]; other site
990282011416	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
990282011417	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
990282011418	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
990282011419	active site
990282011420	P-loop; other site
990282011421	phosphorylation site [posttranslational modification]
990282011422	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
990282011423	active site
990282011424	phosphorylation site [posttranslational modification]
990282011425	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
990282011426	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282011427	DNA-binding site [nucleotide binding]; DNA binding site
990282011428	UTRA domain; Region: UTRA; pfam07702
990282011429	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
990282011430	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
990282011431	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282011432	putative substrate translocation pore; other site
990282011433	regulatory protein UhpC; Provisional; Region: PRK11663
990282011434	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282011435	putative substrate translocation pore; other site
990282011436	sensory histidine kinase UhpB; Provisional; Region: PRK11644
990282011437	MASE1; Region: MASE1; pfam05231
990282011438	Histidine kinase; Region: HisKA_3; pfam07730
990282011439	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282011440	ATP binding site [chemical binding]; other site
990282011441	Mg2+ binding site [ion binding]; other site
990282011442	G-X-G motif; other site
990282011443	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
990282011444	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282011445	active site
990282011446	phosphorylation site [posttranslational modification]
990282011447	intermolecular recognition site; other site
990282011448	dimerization interface [polypeptide binding]; other site
990282011449	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282011450	DNA binding residues [nucleotide binding]
990282011451	dimerization interface [polypeptide binding]; other site
990282011452	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
990282011453	active site
990282011454	catalytic residues [active]
990282011455	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
990282011456	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282011457	putative substrate translocation pore; other site
990282011458	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
990282011459	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
990282011460	substrate binding site [chemical binding]; other site
990282011461	dimer interface [polypeptide binding]; other site
990282011462	ATP binding site [chemical binding]; other site
990282011463	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
990282011464	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
990282011465	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
990282011466	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
990282011467	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
990282011468	putative valine binding site [chemical binding]; other site
990282011469	dimer interface [polypeptide binding]; other site
990282011470	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
990282011471	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
990282011472	PYR/PP interface [polypeptide binding]; other site
990282011473	dimer interface [polypeptide binding]; other site
990282011474	TPP binding site [chemical binding]; other site
990282011475	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
990282011476	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
990282011477	TPP-binding site [chemical binding]; other site
990282011478	dimer interface [polypeptide binding]; other site
990282011479	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
990282011480	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
990282011481	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
990282011482	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282011483	putative substrate translocation pore; other site
990282011484	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
990282011485	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
990282011486	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282011487	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
990282011488	dimerization interface [polypeptide binding]; other site
990282011489	substrate binding pocket [chemical binding]; other site
990282011490	permease DsdX; Provisional; Region: PRK09921
990282011491	gluconate transporter; Region: gntP; TIGR00791
990282011492	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
990282011493	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
990282011494	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
990282011495	catalytic residue [active]
990282011496	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
990282011497	Domain of unknown function (DUF4008); Region: DUF4008; cl14869
990282011498	Domain of unknown function (DUF202); Region: DUF202; pfam02656
990282011499	Predicted membrane protein [Function unknown]; Region: COG2149
990282011500	putative transporter; Validated; Region: PRK03818
990282011501	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
990282011502	TrkA-C domain; Region: TrkA_C; pfam02080
990282011503	TrkA-C domain; Region: TrkA_C; pfam02080
990282011504	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
990282011505	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
990282011506	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
990282011507	putative dimer interface [polypeptide binding]; other site
990282011508	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
990282011509	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
990282011510	putative dimer interface [polypeptide binding]; other site
990282011511	hypothetical protein; Provisional; Region: PRK11616
990282011512	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
990282011513	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
990282011514	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
990282011515	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
990282011516	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
990282011517	catalytic residues [active]
990282011518	central insert; other site
990282011519	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
990282011520	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
990282011521	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
990282011522	heme exporter protein CcmC; Region: ccmC; TIGR01191
990282011523	heme exporter protein CcmB; Region: ccmB; TIGR01190
990282011524	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
990282011525	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282011526	Walker A/P-loop; other site
990282011527	ATP binding site [chemical binding]; other site
990282011528	Q-loop/lid; other site
990282011529	ABC transporter signature motif; other site
990282011530	Walker B; other site
990282011531	D-loop; other site
990282011532	H-loop/switch region; other site
990282011533	Haem-binding domain; Region: Haem_bd; pfam14376
990282011534	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
990282011535	chaperone protein TorD; Validated; Region: torD; PRK04976
990282011536	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
990282011537	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
990282011538	molybdopterin cofactor binding site [chemical binding]; other site
990282011539	substrate binding site [chemical binding]; other site
990282011540	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
990282011541	molybdopterin cofactor binding site; other site
990282011542	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
990282011543	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
990282011544	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
990282011545	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282011546	active site
990282011547	phosphorylation site [posttranslational modification]
990282011548	intermolecular recognition site; other site
990282011549	dimerization interface [polypeptide binding]; other site
990282011550	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
990282011551	DNA binding site [nucleotide binding]
990282011552	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
990282011553	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
990282011554	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
990282011555	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282011556	dimer interface [polypeptide binding]; other site
990282011557	phosphorylation site [posttranslational modification]
990282011558	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282011559	ATP binding site [chemical binding]; other site
990282011560	Mg2+ binding site [ion binding]; other site
990282011561	G-X-G motif; other site
990282011562	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282011563	active site
990282011564	phosphorylation site [posttranslational modification]
990282011565	intermolecular recognition site; other site
990282011566	dimerization interface [polypeptide binding]; other site
990282011567	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
990282011568	putative binding surface; other site
990282011569	active site
990282011570	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282011571	D-galactonate transporter; Region: 2A0114; TIGR00893
990282011572	putative substrate translocation pore; other site
990282011573	galactonate dehydratase; Provisional; Region: PRK14017
990282011574	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
990282011575	putative active site pocket [active]
990282011576	putative metal binding site [ion binding]; other site
990282011577	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
990282011578	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
990282011579	active site
990282011580	intersubunit interface [polypeptide binding]; other site
990282011581	catalytic residue [active]
990282011582	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
990282011583	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
990282011584	Transcriptional regulators [Transcription]; Region: FadR; COG2186
990282011585	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282011586	DNA-binding site [nucleotide binding]; DNA binding site
990282011587	FCD domain; Region: FCD; pfam07729
990282011588	sugar phosphate phosphatase; Provisional; Region: PRK10513
990282011589	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282011590	active site
990282011591	motif I; other site
990282011592	motif II; other site
990282011593	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282011594	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282011595	D-galactonate transporter; Region: 2A0114; TIGR00893
990282011596	putative substrate translocation pore; other site
990282011597	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282011598	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
990282011599	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
990282011600	active site pocket [active]
990282011601	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282011602	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282011603	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
990282011604	putative dimerization interface [polypeptide binding]; other site
990282011605	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
990282011606	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282011607	Mg2+ binding site [ion binding]; other site
990282011608	G-X-G motif; other site
990282011609	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
990282011610	anchoring element; other site
990282011611	dimer interface [polypeptide binding]; other site
990282011612	ATP binding site [chemical binding]; other site
990282011613	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
990282011614	active site
990282011615	putative metal-binding site [ion binding]; other site
990282011616	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
990282011617	recF protein; Region: recf; TIGR00611
990282011618	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282011619	Walker A/P-loop; other site
990282011620	ATP binding site [chemical binding]; other site
990282011621	Q-loop/lid; other site
990282011622	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282011623	ABC transporter signature motif; other site
990282011624	Walker B; other site
990282011625	D-loop; other site
990282011626	H-loop/switch region; other site
990282011627	DNA polymerase III subunit beta; Validated; Region: PRK05643
990282011628	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
990282011629	putative DNA binding surface [nucleotide binding]; other site
990282011630	dimer interface [polypeptide binding]; other site
990282011631	beta-clamp/clamp loader binding surface; other site
990282011632	beta-clamp/translesion DNA polymerase binding surface; other site
990282011633	DnaA N-terminal domain; Region: DnaA_N; pfam11638
990282011634	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
990282011635	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282011636	Walker A motif; other site
990282011637	ATP binding site [chemical binding]; other site
990282011638	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
990282011639	Walker B motif; other site
990282011640	arginine finger; other site
990282011641	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
990282011642	DnaA box-binding interface [nucleotide binding]; other site
990282011643	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
990282011644	ribonuclease P; Reviewed; Region: rnpA; PRK01732
990282011645	hypothetical protein; Validated; Region: PRK00041
990282011646	membrane protein insertase; Provisional; Region: PRK01318
990282011647	Carbohydrate Binding Module 6 (CBM6) and CBM35_like superfamily; Region: CBM6-CBM35-CBM36_like; cl14880
990282011648	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
990282011649	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
990282011650	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
990282011651	trmE is a tRNA modification GTPase; Region: trmE; cd04164
990282011652	G1 box; other site
990282011653	GTP/Mg2+ binding site [chemical binding]; other site
990282011654	Switch I region; other site
990282011655	G2 box; other site
990282011656	Switch II region; other site
990282011657	G3 box; other site
990282011658	G4 box; other site
990282011659	G5 box; other site
990282011660	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
990282011661	putative transferase, LIC12162 family; Region: o_ant_LIC12162; TIGR04331
990282011662	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
990282011663	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
990282011664	putative active site [active]
990282011665	putative NTP binding site [chemical binding]; other site
990282011666	putative nucleic acid binding site [nucleotide binding]; other site
990282011667	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
990282011668	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282011669	putative substrate translocation pore; other site
990282011670	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
990282011671	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282011672	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
990282011673	substrate binding pocket [chemical binding]; other site
990282011674	dimerization interface [polypeptide binding]; other site
990282011675	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
990282011676	Predicted flavoprotein [General function prediction only]; Region: COG0431
990282011677	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
990282011678	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
990282011679	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
990282011680	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282011681	active site
990282011682	motif I; other site
990282011683	motif II; other site
990282011684	transcriptional regulator PhoU; Provisional; Region: PRK11115
990282011685	PhoU domain; Region: PhoU; pfam01895
990282011686	PhoU domain; Region: PhoU; pfam01895
990282011687	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
990282011688	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
990282011689	Walker A/P-loop; other site
990282011690	ATP binding site [chemical binding]; other site
990282011691	Q-loop/lid; other site
990282011692	ABC transporter signature motif; other site
990282011693	Walker B; other site
990282011694	D-loop; other site
990282011695	H-loop/switch region; other site
990282011696	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
990282011697	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282011698	dimer interface [polypeptide binding]; other site
990282011699	conserved gate region; other site
990282011700	putative PBP binding loops; other site
990282011701	ABC-ATPase subunit interface; other site
990282011702	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
990282011703	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282011704	dimer interface [polypeptide binding]; other site
990282011705	conserved gate region; other site
990282011706	putative PBP binding loops; other site
990282011707	ABC-ATPase subunit interface; other site
990282011708	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
990282011709	substrate binding pocket [chemical binding]; other site
990282011710	membrane-bound complex binding site; other site
990282011711	hinge residues; other site
990282011712	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
990282011713	active site
990282011714	P-loop; other site
990282011715	phosphorylation site [posttranslational modification]
990282011716	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
990282011717	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
990282011718	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
990282011719	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
990282011720	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
990282011721	shikimate binding site; other site
990282011722	NAD(P) binding site [chemical binding]; other site
990282011723	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
990282011724	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
990282011725	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
990282011726	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
990282011727	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
990282011728	glutaminase active site [active]
990282011729	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
990282011730	dimer interface [polypeptide binding]; other site
990282011731	active site
990282011732	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
990282011733	dimer interface [polypeptide binding]; other site
990282011734	active site
990282011735	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
990282011736	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
990282011737	Substrate binding site; other site
990282011738	Mg++ binding site; other site
990282011739	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
990282011740	active site
990282011741	substrate binding site [chemical binding]; other site
990282011742	CoA binding site [chemical binding]; other site
990282011743	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
990282011744	Inhibitor of apoptosis-promoting Bax1; Region: Bax1-I; pfam01027
990282011745	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
990282011746	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
990282011747	gamma subunit interface [polypeptide binding]; other site
990282011748	epsilon subunit interface [polypeptide binding]; other site
990282011749	LBP interface [polypeptide binding]; other site
990282011750	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
990282011751	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
990282011752	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
990282011753	alpha subunit interaction interface [polypeptide binding]; other site
990282011754	Walker A motif; other site
990282011755	ATP binding site [chemical binding]; other site
990282011756	Walker B motif; other site
990282011757	inhibitor binding site; inhibition site
990282011758	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
990282011759	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
990282011760	core domain interface [polypeptide binding]; other site
990282011761	delta subunit interface [polypeptide binding]; other site
990282011762	epsilon subunit interface [polypeptide binding]; other site
990282011763	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
990282011764	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
990282011765	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
990282011766	beta subunit interaction interface [polypeptide binding]; other site
990282011767	Walker A motif; other site
990282011768	ATP binding site [chemical binding]; other site
990282011769	Walker B motif; other site
990282011770	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
990282011771	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
990282011772	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
990282011773	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
990282011774	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
990282011775	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
990282011776	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
990282011777	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
990282011778	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
990282011779	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
990282011780	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282011781	S-adenosylmethionine binding site [chemical binding]; other site
990282011782	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
990282011783	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
990282011784	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
990282011785	FMN-binding protein MioC; Provisional; Region: PRK09004
990282011786	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
990282011787	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
990282011788	putative DNA binding site [nucleotide binding]; other site
990282011789	putative Zn2+ binding site [ion binding]; other site
990282011790	AsnC family; Region: AsnC_trans_reg; pfam01037
990282011791	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
990282011792	dimer interface [polypeptide binding]; other site
990282011793	active site
990282011794	hypothetical protein; Provisional; Region: yieM; PRK10997
990282011795	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
990282011796	metal ion-dependent adhesion site (MIDAS); other site
990282011797	regulatory ATPase RavA; Provisional; Region: PRK13531
990282011798	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282011799	Walker A motif; other site
990282011800	ATP binding site [chemical binding]; other site
990282011801	Walker B motif; other site
990282011802	arginine finger; other site
990282011803	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
990282011804	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
990282011805	potassium uptake protein; Region: kup; TIGR00794
990282011806	D-ribose pyranase; Provisional; Region: PRK11797
990282011807	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
990282011808	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
990282011809	Walker A/P-loop; other site
990282011810	ATP binding site [chemical binding]; other site
990282011811	Q-loop/lid; other site
990282011812	ABC transporter signature motif; other site
990282011813	Walker B; other site
990282011814	D-loop; other site
990282011815	H-loop/switch region; other site
990282011816	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
990282011817	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
990282011818	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
990282011819	TM-ABC transporter signature motif; other site
990282011820	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
990282011821	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
990282011822	ligand binding site [chemical binding]; other site
990282011823	dimerization interface [polypeptide binding]; other site
990282011824	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
990282011825	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
990282011826	substrate binding site [chemical binding]; other site
990282011827	dimer interface [polypeptide binding]; other site
990282011828	ATP binding site [chemical binding]; other site
990282011829	transcriptional repressor RbsR; Provisional; Region: PRK10423
990282011830	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
990282011831	DNA binding site [nucleotide binding]
990282011832	domain linker motif; other site
990282011833	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
990282011834	dimerization interface [polypeptide binding]; other site
990282011835	ligand binding site [chemical binding]; other site
990282011836	putative transporter; Provisional; Region: PRK10504
990282011837	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282011838	putative substrate translocation pore; other site
990282011839	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282011840	Transcriptional regulators [Transcription]; Region: FadR; COG2186
990282011841	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282011842	DNA-binding site [nucleotide binding]; DNA binding site
990282011843	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
990282011844	transcriptional regulator HdfR; Provisional; Region: PRK03601
990282011845	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282011846	LysR substrate binding domain; Region: LysR_substrate; pfam03466
990282011847	dimerization interface [polypeptide binding]; other site
990282011848	hypothetical protein; Provisional; Region: PRK11027
990282011849	putative ATP-dependent protease; Provisional; Region: PRK09862
990282011850	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
990282011851	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282011852	Walker A motif; other site
990282011853	ATP binding site [chemical binding]; other site
990282011854	Walker B motif; other site
990282011855	arginine finger; other site
990282011856	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
990282011857	ilvG operon leader peptide; Provisional; Region: PRK10424
990282011858	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
990282011859	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
990282011860	PYR/PP interface [polypeptide binding]; other site
990282011861	dimer interface [polypeptide binding]; other site
990282011862	TPP binding site [chemical binding]; other site
990282011863	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
990282011864	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
990282011865	TPP-binding site [chemical binding]; other site
990282011866	dimer interface [polypeptide binding]; other site
990282011867	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
990282011868	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
990282011869	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
990282011870	homodimer interface [polypeptide binding]; other site
990282011871	substrate-cofactor binding pocket; other site
990282011872	catalytic residue [active]
990282011873	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
990282011874	threonine dehydratase; Reviewed; Region: PRK09224
990282011875	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
990282011876	tetramer interface [polypeptide binding]; other site
990282011877	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282011878	catalytic residue [active]
990282011879	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
990282011880	putative Ile/Val binding site [chemical binding]; other site
990282011881	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
990282011882	putative Ile/Val binding site [chemical binding]; other site
990282011883	Phage-related protein [Function unknown]; Region: COG4679
990282011884	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
990282011885	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282011886	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
990282011887	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
990282011888	putative dimerization interface [polypeptide binding]; other site
990282011889	ketol-acid reductoisomerase; Validated; Region: PRK05225
990282011890	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
990282011891	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
990282011892	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
990282011893	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
990282011894	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
990282011895	Nicotinamide mononucleotide transporter; Region: NMN_transporter; cl01256
990282011896	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
990282011897	Part of AAA domain; Region: AAA_19; pfam13245
990282011898	Family description; Region: UvrD_C_2; pfam13538
990282011899	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
990282011900	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
990282011901	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
990282011902	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
990282011903	ATP binding site [chemical binding]; other site
990282011904	Mg++ binding site [ion binding]; other site
990282011905	motif III; other site
990282011906	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
990282011907	nucleotide binding region [chemical binding]; other site
990282011908	ATP-binding site [chemical binding]; other site
990282011909	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
990282011910	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
990282011911	catalytic residues [active]
990282011912	transcription termination factor Rho; Provisional; Region: rho; PRK09376
990282011913	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
990282011914	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
990282011915	RNA binding site [nucleotide binding]; other site
990282011916	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
990282011917	multimer interface [polypeptide binding]; other site
990282011918	Walker A motif; other site
990282011919	ATP binding site [chemical binding]; other site
990282011920	Walker B motif; other site
990282011921	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
990282011922	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
990282011923	Mg++ binding site [ion binding]; other site
990282011924	putative catalytic motif [active]
990282011925	substrate binding site [chemical binding]; other site
990282011926	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
990282011927	Chain length determinant protein; Region: Wzz; pfam02706
990282011928	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
990282011929	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
990282011930	active site
990282011931	homodimer interface [polypeptide binding]; other site
990282011932	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
990282011933	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
990282011934	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
990282011935	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
990282011936	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
990282011937	NAD binding site [chemical binding]; other site
990282011938	substrate binding site [chemical binding]; other site
990282011939	homodimer interface [polypeptide binding]; other site
990282011940	active site
990282011941	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
990282011942	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
990282011943	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
990282011944	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
990282011945	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
990282011946	inhibitor-cofactor binding pocket; inhibition site
990282011947	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282011948	catalytic residue [active]
990282011949	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
990282011950	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
990282011951	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
990282011952	putative common antigen polymerase; Provisional; Region: PRK02975
990282011953	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
990282011954	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
990282011955	putative transport protein YifK; Provisional; Region: PRK10746
990282011956	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
990282011957	HemY protein N-terminus; Region: HemY_N; pfam07219
990282011958	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
990282011959	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
990282011960	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
990282011961	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
990282011962	active site
990282011963	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
990282011964	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
990282011965	domain interfaces; other site
990282011966	active site
990282011967	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
990282011968	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
990282011969	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
990282011970	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
990282011971	putative iron binding site [ion binding]; other site
990282011972	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
990282011973	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
990282011974	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
990282011975	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
990282011976	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
990282011977	hypothetical protein; Provisional; Region: PRK10963
990282011978	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
990282011979	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
990282011980	active site
990282011981	Int/Topo IB signature motif; other site
990282011982	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
990282011983	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282011984	motif II; other site
990282011985	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
990282011986	Part of AAA domain; Region: AAA_19; pfam13245
990282011987	Family description; Region: UvrD_C_2; pfam13538
990282011988	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
990282011989	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
990282011990	Cl binding site [ion binding]; other site
990282011991	oligomer interface [polypeptide binding]; other site
990282011992	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
990282011993	hypothetical protein; Provisional; Region: PRK11371
990282011994	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
990282011995	EamA-like transporter family; Region: EamA; cl17759
990282011996	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
990282011997	CoenzymeA binding site [chemical binding]; other site
990282011998	subunit interaction site [polypeptide binding]; other site
990282011999	PHB binding site; other site
990282012000	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
990282012001	dimerization interface [polypeptide binding]; other site
990282012002	substrate binding site [chemical binding]; other site
990282012003	active site
990282012004	calcium binding site [ion binding]; other site
990282012005	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
990282012006	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
990282012007	ATP binding site [chemical binding]; other site
990282012008	putative Mg++ binding site [ion binding]; other site
990282012009	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
990282012010	nucleotide binding region [chemical binding]; other site
990282012011	ATP-binding site [chemical binding]; other site
990282012012	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
990282012013	Helicase and RNase D C-terminal; Region: HRDC; smart00341
990282012014	threonine efflux system; Provisional; Region: PRK10229
990282012015	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
990282012016	lysophospholipase L2; Provisional; Region: PRK10749
990282012017	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
990282012018	putative hydrolase; Provisional; Region: PRK10976
990282012019	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282012020	active site
990282012021	motif I; other site
990282012022	motif II; other site
990282012023	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282012024	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
990282012025	EamA-like transporter family; Region: EamA; pfam00892
990282012026	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
990282012027	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282012028	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
990282012029	putative dimerization interface [polypeptide binding]; other site
990282012030	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
990282012031	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
990282012032	THF binding site; other site
990282012033	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
990282012034	substrate binding site [chemical binding]; other site
990282012035	THF binding site; other site
990282012036	zinc-binding site [ion binding]; other site
990282012037	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
990282012038	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282012039	FeS/SAM binding site; other site
990282012040	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
990282012041	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
990282012042	uridine phosphorylase; Provisional; Region: PRK11178
990282012043	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
990282012044	DNA recombination protein RmuC; Provisional; Region: PRK10361
990282012045	RmuC family; Region: RmuC; pfam02646
990282012046	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
990282012047	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282012048	S-adenosylmethionine binding site [chemical binding]; other site
990282012049	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
990282012050	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
990282012051	SCP-2 sterol transfer family; Region: SCP2; pfam02036
990282012052	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
990282012053	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
990282012054	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
990282012055	sec-independent translocase; Provisional; Region: PRK01770
990282012056	sec-independent translocase; Provisional; Region: tatB; PRK00404
990282012057	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
990282012058	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
990282012059	active site
990282012060	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
990282012061	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
990282012062	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
990282012063	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
990282012064	FMN reductase; Validated; Region: fre; PRK08051
990282012065	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
990282012066	FAD binding pocket [chemical binding]; other site
990282012067	FAD binding motif [chemical binding]; other site
990282012068	phosphate binding motif [ion binding]; other site
990282012069	beta-alpha-beta structure motif; other site
990282012070	NAD binding pocket [chemical binding]; other site
990282012071	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
990282012072	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
990282012073	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
990282012074	dimer interface [polypeptide binding]; other site
990282012075	active site
990282012076	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
990282012077	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
990282012078	substrate binding site [chemical binding]; other site
990282012079	oxyanion hole (OAH) forming residues; other site
990282012080	trimer interface [polypeptide binding]; other site
990282012081	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
990282012082	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
990282012083	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
990282012084	proline dipeptidase; Provisional; Region: PRK13607
990282012085	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
990282012086	active site
990282012087	hypothetical protein; Provisional; Region: PRK11568
990282012088	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
990282012089	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
990282012090	potassium transporter; Provisional; Region: PRK10750
990282012091	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
990282012092	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
990282012093	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
990282012094	Walker A motif; other site
990282012095	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
990282012096	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
990282012097	GTP binding site; other site
990282012098	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
990282012099	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
990282012100	serine/threonine protein kinase; Provisional; Region: PRK11768
990282012101	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
990282012102	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
990282012103	catalytic residues [active]
990282012104	hinge region; other site
990282012105	alpha helical domain; other site
990282012106	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
990282012107	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
990282012108	putative acyl-acceptor binding pocket; other site
990282012109	DNA polymerase I; Provisional; Region: PRK05755
990282012110	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
990282012111	active site
990282012112	metal binding site 1 [ion binding]; metal-binding site
990282012113	putative 5' ssDNA interaction site; other site
990282012114	metal binding site 3; metal-binding site
990282012115	metal binding site 2 [ion binding]; metal-binding site
990282012116	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
990282012117	putative DNA binding site [nucleotide binding]; other site
990282012118	putative metal binding site [ion binding]; other site
990282012119	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
990282012120	active site
990282012121	catalytic site [active]
990282012122	substrate binding site [chemical binding]; other site
990282012123	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
990282012124	active site
990282012125	DNA binding site [nucleotide binding]
990282012126	catalytic site [active]
990282012127	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
990282012128	G1 box; other site
990282012129	GTP/Mg2+ binding site [chemical binding]; other site
990282012130	Switch I region; other site
990282012131	G2 box; other site
990282012132	G3 box; other site
990282012133	Switch II region; other site
990282012134	G4 box; other site
990282012135	G5 box; other site
990282012136	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
990282012137	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
990282012138	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282012139	FeS/SAM binding site; other site
990282012140	HemN C-terminal domain; Region: HemN_C; pfam06969
990282012141	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
990282012142	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282012143	active site
990282012144	phosphorylation site [posttranslational modification]
990282012145	intermolecular recognition site; other site
990282012146	dimerization interface [polypeptide binding]; other site
990282012147	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282012148	Walker A motif; other site
990282012149	ATP binding site [chemical binding]; other site
990282012150	Walker B motif; other site
990282012151	arginine finger; other site
990282012152	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
990282012153	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
990282012154	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
990282012155	putative active site [active]
990282012156	heme pocket [chemical binding]; other site
990282012157	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282012158	dimer interface [polypeptide binding]; other site
990282012159	phosphorylation site [posttranslational modification]
990282012160	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282012161	ATP binding site [chemical binding]; other site
990282012162	Mg2+ binding site [ion binding]; other site
990282012163	G-X-G motif; other site
990282012164	glutamine synthetase; Provisional; Region: glnA; PRK09469
990282012165	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
990282012166	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
990282012167	GTP-binding protein; Provisional; Region: PRK10218
990282012168	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
990282012169	G1 box; other site
990282012170	putative GEF interaction site [polypeptide binding]; other site
990282012171	GTP/Mg2+ binding site [chemical binding]; other site
990282012172	Switch I region; other site
990282012173	G2 box; other site
990282012174	G3 box; other site
990282012175	Switch II region; other site
990282012176	G4 box; other site
990282012177	G5 box; other site
990282012178	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
990282012179	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
990282012180	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282012181	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
990282012182	active site
990282012183	motif I; other site
990282012184	motif II; other site
990282012185	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282012186	coproporphyrinogen III oxidase; Validated; Region: PRK08208
990282012187	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282012188	FeS/SAM binding site; other site
990282012189	HemN C-terminal domain; Region: HemN_C; pfam06969
990282012190	Sulfatase; Region: Sulfatase; cl17466
990282012191	YheC/D like ATP-grasp; Region: ATPgrasp_YheCD; pfam14398
990282012192	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
990282012193	Leucine-rich repeats; other site
990282012194	Substrate binding site [chemical binding]; other site
990282012195	outer membrane porin L; Provisional; Region: ompL; PRK09980
990282012196	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
990282012197	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282012198	putative substrate translocation pore; other site
990282012199	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
990282012200	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
990282012201	alpha-glucosidase; Provisional; Region: PRK10426
990282012202	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
990282012203	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
990282012204	putative active site [active]
990282012205	putative catalytic site [active]
990282012206	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
990282012207	active site
990282012208	catalytic residues [active]
990282012209	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
990282012210	dimerization interface [polypeptide binding]; other site
990282012211	putative active cleft [active]
990282012212	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
990282012213	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
990282012214	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
990282012215	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
990282012216	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
990282012217	substrate binding site [chemical binding]; other site
990282012218	ATP binding site [chemical binding]; other site
990282012219	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
990282012220	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
990282012221	putative DNA binding site [nucleotide binding]; other site
990282012222	putative Zn2+ binding site [ion binding]; other site
990282012223	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
990282012224	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
990282012225	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282012226	motif II; other site
990282012227	hypothetical protein; Reviewed; Region: PRK01637
990282012228	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
990282012229	putative active site [active]
990282012230	dimerization interface [polypeptide binding]; other site
990282012231	putative tRNAtyr binding site [nucleotide binding]; other site
990282012232	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282012233	Coenzyme A binding pocket [chemical binding]; other site
990282012234	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
990282012235	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
990282012236	non-specific DNA binding site [nucleotide binding]; other site
990282012237	salt bridge; other site
990282012238	sequence-specific DNA binding site [nucleotide binding]; other site
990282012239	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
990282012240	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
990282012241	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
990282012242	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
990282012243	Predicted transcriptional regulator [Transcription]; Region: COG2944
990282012244	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
990282012245	non-specific DNA binding site [nucleotide binding]; other site
990282012246	salt bridge; other site
990282012247	sequence-specific DNA binding site [nucleotide binding]; other site
990282012248	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
990282012249	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
990282012250	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
990282012251	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
990282012252	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
990282012253	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
990282012254	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
990282012255	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
990282012256	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
990282012257	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
990282012258	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
990282012259	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
990282012260	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
990282012261	non-specific DNA binding site [nucleotide binding]; other site
990282012262	salt bridge; other site
990282012263	sequence-specific DNA binding site [nucleotide binding]; other site
990282012264	Cupin domain; Region: Cupin_2; cl17218
990282012265	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
990282012266	lactaldehyde reductase; Region: lactal_redase; TIGR02638
990282012267	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
990282012268	dimer interface [polypeptide binding]; other site
990282012269	active site
990282012270	metal binding site [ion binding]; metal-binding site
990282012271	rhamnulose-1-phosphate aldolase; Provisional; Region: PRK03634
990282012272	intersubunit interface [polypeptide binding]; other site
990282012273	active site
990282012274	Zn2+ binding site [ion binding]; other site
990282012275	L-rhamnose isomerase; Provisional; Region: PRK01076
990282012276	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
990282012277	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
990282012278	N- and C-terminal domain interface [polypeptide binding]; other site
990282012279	active site
990282012280	putative catalytic site [active]
990282012281	metal binding site [ion binding]; metal-binding site
990282012282	ATP binding site [chemical binding]; other site
990282012283	rhamnulokinase; Provisional; Region: rhaB; PRK10640
990282012284	carbohydrate binding site [chemical binding]; other site
990282012285	transcriptional activator RhaS; Provisional; Region: PRK13503
990282012286	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
990282012287	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282012288	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282012289	transcriptional activator RhaR; Provisional; Region: PRK13502
990282012290	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
990282012291	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282012292	L-rhamnose-proton symport protein (RhaT); Region: RhaT; pfam06379
990282012293	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
990282012294	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
990282012295	DctM-like transporters; Region: DctM; pfam06808
990282012296	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
990282012297	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
990282012298	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
990282012299	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
990282012300	superoxide dismutase; Provisional; Region: PRK10925
990282012301	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
990282012302	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
990282012303	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
990282012304	MOSC domain; Region: MOSC; pfam03473
990282012305	3-alpha domain; Region: 3-alpha; pfam03475
990282012306	SnoaL-like domain; Region: SnoaL_2; pfam12680
990282012307	two-component sensor protein; Provisional; Region: cpxA; PRK09470
990282012308	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
990282012309	dimerization interface [polypeptide binding]; other site
990282012310	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282012311	dimer interface [polypeptide binding]; other site
990282012312	phosphorylation site [posttranslational modification]
990282012313	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282012314	ATP binding site [chemical binding]; other site
990282012315	Mg2+ binding site [ion binding]; other site
990282012316	G-X-G motif; other site
990282012317	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
990282012318	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282012319	active site
990282012320	intermolecular recognition site; other site
990282012321	dimerization interface [polypeptide binding]; other site
990282012322	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
990282012323	DNA binding site [nucleotide binding]
990282012324	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
990282012325	dimer interface [polypeptide binding]; other site
990282012326	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
990282012327	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
990282012328	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
990282012329	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
990282012330	active site
990282012331	ADP/pyrophosphate binding site [chemical binding]; other site
990282012332	dimerization interface [polypeptide binding]; other site
990282012333	allosteric effector site; other site
990282012334	fructose-1,6-bisphosphate binding site; other site
990282012335	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
990282012336	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
990282012337	substrate binding pocket [chemical binding]; other site
990282012338	membrane-bound complex binding site; other site
990282012339	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
990282012340	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
990282012341	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
990282012342	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
990282012343	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
990282012344	putative substrate binding site [chemical binding]; other site
990282012345	putative ATP binding site [chemical binding]; other site
990282012346	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
990282012347	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
990282012348	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282012349	DNA-binding site [nucleotide binding]; DNA binding site
990282012350	Alanine racemase, C-terminal domain; Region: Ala_racemase_C; cl08293
990282012351	UTRA domain; Region: UTRA; pfam07702
990282012352	CDP-diacylglycerol pyrophosphatase; Region: CDH; cl00934
990282012353	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
990282012354	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
990282012355	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
990282012356	putative N- and C-terminal domain interface [polypeptide binding]; other site
990282012357	putative active site [active]
990282012358	putative MgATP binding site [chemical binding]; other site
990282012359	catalytic site [active]
990282012360	metal binding site [ion binding]; metal-binding site
990282012361	putative carbohydrate binding site [chemical binding]; other site
990282012362	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
990282012363	transcriptional regulator LsrR; Provisional; Region: PRK15418
990282012364	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
990282012365	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
990282012366	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
990282012367	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
990282012368	Walker A/P-loop; other site
990282012369	ATP binding site [chemical binding]; other site
990282012370	Q-loop/lid; other site
990282012371	ABC transporter signature motif; other site
990282012372	Walker B; other site
990282012373	D-loop; other site
990282012374	H-loop/switch region; other site
990282012375	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
990282012376	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
990282012377	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
990282012378	TM-ABC transporter signature motif; other site
990282012379	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
990282012380	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
990282012381	TM-ABC transporter signature motif; other site
990282012382	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
990282012383	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
990282012384	ligand binding site [chemical binding]; other site
990282012385	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
990282012386	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
990282012387	putative active site; other site
990282012388	catalytic residue [active]
990282012389	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
990282012390	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
990282012391	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
990282012392	substrate binding site [chemical binding]; other site
990282012393	hexamer interface [polypeptide binding]; other site
990282012394	metal binding site [ion binding]; metal-binding site
990282012395	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
990282012396	triosephosphate isomerase; Provisional; Region: PRK14567
990282012397	substrate binding site [chemical binding]; other site
990282012398	dimer interface [polypeptide binding]; other site
990282012399	catalytic triad [active]
990282012400	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
990282012401	Predicted membrane protein [Function unknown]; Region: COG3152
990282012402	ferredoxin-NADP reductase; Provisional; Region: PRK10926
990282012403	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
990282012404	FAD binding pocket [chemical binding]; other site
990282012405	FAD binding motif [chemical binding]; other site
990282012406	phosphate binding motif [ion binding]; other site
990282012407	beta-alpha-beta structure motif; other site
990282012408	NAD binding pocket [chemical binding]; other site
990282012409	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
990282012410	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
990282012411	putative active site [active]
990282012412	glycerol kinase; Provisional; Region: glpK; PRK00047
990282012413	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
990282012414	N- and C-terminal domain interface [polypeptide binding]; other site
990282012415	active site
990282012416	MgATP binding site [chemical binding]; other site
990282012417	catalytic site [active]
990282012418	metal binding site [ion binding]; metal-binding site
990282012419	glycerol binding site [chemical binding]; other site
990282012420	homotetramer interface [polypeptide binding]; other site
990282012421	homodimer interface [polypeptide binding]; other site
990282012422	FBP binding site [chemical binding]; other site
990282012423	protein IIAGlc interface [polypeptide binding]; other site
990282012424	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
990282012425	amphipathic channel; other site
990282012426	Asn-Pro-Ala signature motifs; other site
990282012427	septal ring assembly protein ZapB; Provisional; Region: PRK15422
990282012428	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
990282012429	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
990282012430	UbiA prenyltransferase family; Region: UbiA; pfam01040
990282012431	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
990282012432	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282012433	Walker A motif; other site
990282012434	ATP binding site [chemical binding]; other site
990282012435	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
990282012436	Walker B motif; other site
990282012437	arginine finger; other site
990282012438	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
990282012439	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
990282012440	active site
990282012441	HslU subunit interaction site [polypeptide binding]; other site
990282012442	essential cell division protein FtsN; Provisional; Region: PRK10927
990282012443	cell division protein FtsN; Provisional; Region: PRK12757
990282012444	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
990282012445	DNA binding site [nucleotide binding]
990282012446	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
990282012447	domain linker motif; other site
990282012448	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
990282012449	dimerization interface [polypeptide binding]; other site
990282012450	ligand binding site [chemical binding]; other site
990282012451	primosome assembly protein PriA; Validated; Region: PRK05580
990282012452	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
990282012453	ATP binding site [chemical binding]; other site
990282012454	putative Mg++ binding site [ion binding]; other site
990282012455	helicase superfamily c-terminal domain; Region: HELICc; smart00490
990282012456	ATP-binding site [chemical binding]; other site
990282012457	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
990282012458	conserved hypothetical protein; Region: chp_urease_rgn; TIGR02117
990282012459	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
990282012460	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
990282012461	dimerization interface [polypeptide binding]; other site
990282012462	DNA binding site [nucleotide binding]
990282012463	corepressor binding sites; other site
990282012464	cystathionine gamma-synthase; Provisional; Region: PRK08045
990282012465	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
990282012466	homodimer interface [polypeptide binding]; other site
990282012467	substrate-cofactor binding pocket; other site
990282012468	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282012469	catalytic residue [active]
990282012470	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
990282012471	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
990282012472	putative catalytic residues [active]
990282012473	putative nucleotide binding site [chemical binding]; other site
990282012474	putative aspartate binding site [chemical binding]; other site
990282012475	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
990282012476	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
990282012477	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
990282012478	mechanosensitive channel MscS; Provisional; Region: PRK10334
990282012479	Conserved TM helix; Region: TM_helix; pfam05552
990282012480	Mechanosensitive ion channel; Region: MS_channel; pfam00924
990282012481	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
990282012482	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
990282012483	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
990282012484	active site
990282012485	metal binding site [ion binding]; metal-binding site
990282012486	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
990282012487	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
990282012488	FAD binding site [chemical binding]; other site
990282012489	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
990282012490	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
990282012491	heme binding site [chemical binding]; other site
990282012492	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
990282012493	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
990282012494	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
990282012495	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
990282012496	dimer interface [polypeptide binding]; other site
990282012497	active site
990282012498	metal binding site [ion binding]; metal-binding site
990282012499	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
990282012500	active site
990282012501	intersubunit interactions; other site
990282012502	catalytic residue [active]
990282012503	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
990282012504	dimerization domain swap beta strand [polypeptide binding]; other site
990282012505	regulatory protein interface [polypeptide binding]; other site
990282012506	active site
990282012507	regulatory phosphorylation site [posttranslational modification]; other site
990282012508	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
990282012509	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
990282012510	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
990282012511	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
990282012512	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
990282012513	active site
990282012514	phosphorylation site [posttranslational modification]
990282012515	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
990282012516	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
990282012517	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
990282012518	active site
990282012519	P-loop; other site
990282012520	phosphorylation site [posttranslational modification]
990282012521	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
990282012522	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
990282012523	dimer interface [polypeptide binding]; other site
990282012524	active site
990282012525	glycine loop; other site
990282012526	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282012527	FeS/SAM binding site; other site
990282012528	pyruvate formate lyase II activase; Provisional; Region: PRK10076
990282012529	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
990282012530	active site
990282012531	P-loop; other site
990282012532	phosphorylation site [posttranslational modification]
990282012533	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
990282012534	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282012535	hypothetical protein; Provisional; Region: PRK10649
990282012536	Sulfatase; Region: Sulfatase; pfam00884
990282012537	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
990282012538	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
990282012539	acetylornithine deacetylase; Provisional; Region: PRK05111
990282012540	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
990282012541	metal binding site [ion binding]; metal-binding site
990282012542	putative dimer interface [polypeptide binding]; other site
990282012543	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
990282012544	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
990282012545	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
990282012546	nucleotide binding site [chemical binding]; other site
990282012547	N-acetyl-L-glutamate binding site [chemical binding]; other site
990282012548	argininosuccinate lyase; Provisional; Region: PRK04833
990282012549	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
990282012550	active sites [active]
990282012551	tetramer interface [polypeptide binding]; other site
990282012552	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
990282012553	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282012554	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
990282012555	dimerization interface [polypeptide binding]; other site
990282012556	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
990282012557	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
990282012558	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
990282012559	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
990282012560	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
990282012561	hypothetical protein; Provisional; Region: PRK11056
990282012562	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
990282012563	Protein of unknown function (DUF3164); Region: DUF3164; pfam11363
990282012564	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282012565	S-adenosylmethionine binding site [chemical binding]; other site
990282012566	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
990282012567	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
990282012568	N-terminal plug; other site
990282012569	ligand-binding site [chemical binding]; other site
990282012570	glutamate racemase; Provisional; Region: PRK00865
990282012571	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
990282012572	FAD binding domain; Region: FAD_binding_4; pfam01565
990282012573	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
990282012574	Biotin operon repressor [Transcription]; Region: BirA; COG1654
990282012575	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
990282012576	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
990282012577	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
990282012578	pantothenate kinase; Provisional; Region: PRK05439
990282012579	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
990282012580	ATP-binding site [chemical binding]; other site
990282012581	CoA-binding site [chemical binding]; other site
990282012582	Mg2+-binding site [ion binding]; other site
990282012583	elongation factor Tu; Reviewed; Region: PRK00049
990282012584	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
990282012585	G1 box; other site
990282012586	GEF interaction site [polypeptide binding]; other site
990282012587	GTP/Mg2+ binding site [chemical binding]; other site
990282012588	Switch I region; other site
990282012589	G2 box; other site
990282012590	G3 box; other site
990282012591	Switch II region; other site
990282012592	G4 box; other site
990282012593	G5 box; other site
990282012594	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
990282012595	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
990282012596	Antibiotic Binding Site [chemical binding]; other site
990282012597	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
990282012598	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
990282012599	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
990282012600	putative homodimer interface [polypeptide binding]; other site
990282012601	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
990282012602	heterodimer interface [polypeptide binding]; other site
990282012603	homodimer interface [polypeptide binding]; other site
990282012604	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
990282012605	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
990282012606	23S rRNA interface [nucleotide binding]; other site
990282012607	L7/L12 interface [polypeptide binding]; other site
990282012608	putative thiostrepton binding site; other site
990282012609	L25 interface [polypeptide binding]; other site
990282012610	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
990282012611	mRNA/rRNA interface [nucleotide binding]; other site
990282012612	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
990282012613	23S rRNA interface [nucleotide binding]; other site
990282012614	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
990282012615	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
990282012616	core dimer interface [polypeptide binding]; other site
990282012617	peripheral dimer interface [polypeptide binding]; other site
990282012618	L10 interface [polypeptide binding]; other site
990282012619	L11 interface [polypeptide binding]; other site
990282012620	putative EF-Tu interaction site [polypeptide binding]; other site
990282012621	putative EF-G interaction site [polypeptide binding]; other site
990282012622	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
990282012623	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
990282012624	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
990282012625	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
990282012626	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
990282012627	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
990282012628	RPB3 interaction site [polypeptide binding]; other site
990282012629	RPB1 interaction site [polypeptide binding]; other site
990282012630	RPB11 interaction site [polypeptide binding]; other site
990282012631	RPB10 interaction site [polypeptide binding]; other site
990282012632	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
990282012633	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
990282012634	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
990282012635	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
990282012636	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
990282012637	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
990282012638	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
990282012639	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
990282012640	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
990282012641	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
990282012642	DNA binding site [nucleotide binding]
990282012643	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
990282012644	type III secretion system protein; Provisional; Region: PRK15384
990282012645	non-LEE encoded effector protein NleB; Provisional; Region: PRK15382
990282012646	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
990282012647	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282012648	FeS/SAM binding site; other site
990282012649	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
990282012650	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
990282012651	ThiS interaction site; other site
990282012652	putative active site [active]
990282012653	tetramer interface [polypeptide binding]; other site
990282012654	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
990282012655	thiS-thiF/thiG interaction site; other site
990282012656	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
990282012657	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
990282012658	ATP binding site [chemical binding]; other site
990282012659	substrate interface [chemical binding]; other site
990282012660	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
990282012661	thiamine phosphate binding site [chemical binding]; other site
990282012662	active site
990282012663	pyrophosphate binding site [ion binding]; other site
990282012664	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
990282012665	ThiC-associated domain; Region: ThiC-associated; pfam13667
990282012666	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
990282012667	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
990282012668	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
990282012669	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
990282012670	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
990282012671	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
990282012672	putative NADH binding site [chemical binding]; other site
990282012673	putative active site [active]
990282012674	nudix motif; other site
990282012675	putative metal binding site [ion binding]; other site
990282012676	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
990282012677	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
990282012678	substrate binding site [chemical binding]; other site
990282012679	active site
990282012680	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
990282012681	Active_site [active]
990282012682	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
990282012683	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
990282012684	IHF dimer interface [polypeptide binding]; other site
990282012685	IHF - DNA interface [nucleotide binding]; other site
990282012686	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
990282012687	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
990282012688	dimer interface [polypeptide binding]; other site
990282012689	sensor protein ZraS; Provisional; Region: PRK10364
990282012690	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282012691	dimer interface [polypeptide binding]; other site
990282012692	phosphorylation site [posttranslational modification]
990282012693	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282012694	ATP binding site [chemical binding]; other site
990282012695	Mg2+ binding site [ion binding]; other site
990282012696	G-X-G motif; other site
990282012697	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
990282012698	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282012699	active site
990282012700	phosphorylation site [posttranslational modification]
990282012701	intermolecular recognition site; other site
990282012702	dimerization interface [polypeptide binding]; other site
990282012703	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282012704	Walker A motif; other site
990282012705	ATP binding site [chemical binding]; other site
990282012706	Walker B motif; other site
990282012707	arginine finger; other site
990282012708	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
990282012709	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
990282012710	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
990282012711	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
990282012712	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
990282012713	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
990282012714	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
990282012715	purine monophosphate binding site [chemical binding]; other site
990282012716	dimer interface [polypeptide binding]; other site
990282012717	putative catalytic residues [active]
990282012718	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
990282012719	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
990282012720	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282012721	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
990282012722	Coenzyme A binding pocket [chemical binding]; other site
990282012723	homoserine O-succinyltransferase; Provisional; Region: PRK05368
990282012724	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
990282012725	proposed active site lysine [active]
990282012726	conserved cys residue [active]
990282012727	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
990282012728	malate synthase A; Region: malate_syn_A; TIGR01344
990282012729	active site
990282012730	isocitrate lyase; Provisional; Region: PRK15063
990282012731	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
990282012732	tetramer interface [polypeptide binding]; other site
990282012733	active site
990282012734	Mg2+/Mn2+ binding site [ion binding]; other site
990282012735	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
990282012736	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
990282012737	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
990282012738	transcriptional repressor IclR; Provisional; Region: PRK11569
990282012739	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
990282012740	Bacterial transcriptional regulator; Region: IclR; pfam01614
990282012741	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
990282012742	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
990282012743	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
990282012744	substrate binding pocket [chemical binding]; other site
990282012745	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
990282012746	B12 binding site [chemical binding]; other site
990282012747	cobalt ligand [ion binding]; other site
990282012748	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
990282012749	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
990282012750	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
990282012751	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
990282012752	active site pocket [active]
990282012753	oxyanion hole [active]
990282012754	catalytic triad [active]
990282012755	active site nucleophile [active]
990282012756	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
990282012757	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
990282012758	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
990282012759	RNA binding surface [nucleotide binding]; other site
990282012760	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
990282012761	probable active site [active]
990282012762	hypothetical protein; Provisional; Region: PRK10515
990282012763	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
990282012764	Sodium Bile acid symporter family; Region: SBF; pfam01758
990282012765	Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045
990282012766	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
990282012767	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
990282012768	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
990282012769	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
990282012770	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
990282012771	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
990282012772	Phage-related baseplate assembly protein [General function prediction only]; Region: COG3948
990282012773	Phage baseplate assembly protein W [General function prediction only]; Region: COG3628
990282012774	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
990282012775	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
990282012776	Ligand binding site; other site
990282012777	Putative Catalytic site; other site
990282012778	DXD motif; other site
990282012779	Predicted membrane protein [Function unknown]; Region: COG2246
990282012780	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
990282012781	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
990282012782	Phage protein D [General function prediction only]; Region: COG3500
990282012783	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
990282012784	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
990282012785	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
990282012786	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
990282012787	Phage tail tube protein FII [General function prediction only]; Region: COG3498
990282012788	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
990282012789	Gp37 protein; Region: Gp37; pfam09646
990282012790	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
990282012791	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
990282012792	N-acetyl-D-glucosamine binding site [chemical binding]; other site
990282012793	catalytic residue [active]
990282012794	Protein of unknown function (DUF4063); Region: DUF4063; pfam13272
990282012795	Uncharacterized conserved protein [Function unknown]; Region: COG5566
990282012796	aspartate kinase III; Validated; Region: PRK09084
990282012797	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
990282012798	nucleotide binding site [chemical binding]; other site
990282012799	substrate binding site [chemical binding]; other site
990282012800	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
990282012801	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
990282012802	dimer interface [polypeptide binding]; other site
990282012803	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
990282012804	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
990282012805	active site
990282012806	dimer interface [polypeptide binding]; other site
990282012807	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
990282012808	dimer interface [polypeptide binding]; other site
990282012809	active site
990282012810	Exopolysaccharide production protein YjbE; Region: YjbE; pfam11106
990282012811	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
990282012812	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
990282012813	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
990282012814	Predicted membrane protein [Function unknown]; Region: COG3223
990282012815	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
990282012816	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282012817	dimer interface [polypeptide binding]; other site
990282012818	conserved gate region; other site
990282012819	putative PBP binding loops; other site
990282012820	ABC-ATPase subunit interface; other site
990282012821	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
990282012822	dimer interface [polypeptide binding]; other site
990282012823	conserved gate region; other site
990282012824	putative PBP binding loops; other site
990282012825	ABC-ATPase subunit interface; other site
990282012826	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
990282012827	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
990282012828	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
990282012829	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
990282012830	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
990282012831	Walker A/P-loop; other site
990282012832	ATP binding site [chemical binding]; other site
990282012833	Q-loop/lid; other site
990282012834	ABC transporter signature motif; other site
990282012835	Walker B; other site
990282012836	D-loop; other site
990282012837	H-loop/switch region; other site
990282012838	TOBE domain; Region: TOBE_2; pfam08402
990282012839	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
990282012840	trimer interface; other site
990282012841	sugar binding site [chemical binding]; other site
990282012842	maltose regulon periplasmic protein; Provisional; Region: PRK10564
990282012843	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
990282012844	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
990282012845	UbiA prenyltransferase family; Region: UbiA; pfam01040
990282012846	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
990282012847	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
990282012848	putative acyl-acceptor binding pocket; other site
990282012849	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
990282012850	LexA repressor; Validated; Region: PRK00215
990282012851	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
990282012852	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
990282012853	Catalytic site [active]
990282012854	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
990282012855	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
990282012856	hypothetical protein; Provisional; Region: PRK10428
990282012857	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
990282012858	metal binding site 2 [ion binding]; metal-binding site
990282012859	putative DNA binding helix; other site
990282012860	metal binding site 1 [ion binding]; metal-binding site
990282012861	dimer interface [polypeptide binding]; other site
990282012862	structural Zn2+ binding site [ion binding]; other site
990282012863	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
990282012864	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
990282012865	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
990282012866	FMN binding site [chemical binding]; other site
990282012867	active site
990282012868	catalytic residues [active]
990282012869	substrate binding site [chemical binding]; other site
990282012870	phage shock protein G; Reviewed; Region: pspG; PRK09459
990282012871	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
990282012872	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
990282012873	NADP binding site [chemical binding]; other site
990282012874	dimer interface [polypeptide binding]; other site
990282012875	replicative DNA helicase; Provisional; Region: PRK08006
990282012876	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
990282012877	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
990282012878	Walker A motif; other site
990282012879	ATP binding site [chemical binding]; other site
990282012880	Walker B motif; other site
990282012881	DNA binding loops [nucleotide binding]
990282012882	alanine racemase; Reviewed; Region: alr; PRK00053
990282012883	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
990282012884	active site
990282012885	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
990282012886	substrate binding site [chemical binding]; other site
990282012887	catalytic residues [active]
990282012888	dimer interface [polypeptide binding]; other site
990282012889	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
990282012890	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
990282012891	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282012892	homodimer interface [polypeptide binding]; other site
990282012893	catalytic residue [active]
990282012894	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
990282012895	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282012896	active site
990282012897	motif I; other site
990282012898	motif II; other site
990282012899	Uncharacterized conserved protein [Function unknown]; Region: COG0432
990282012900	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
990282012901	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
990282012902	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
990282012903	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
990282012904	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
990282012905	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
990282012906	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
990282012907	dimer interface [polypeptide binding]; other site
990282012908	ssDNA binding site [nucleotide binding]; other site
990282012909	tetramer (dimer of dimers) interface [polypeptide binding]; other site
990282012910	hypothetical protein; Validated; Region: PRK09039
990282012911	Zinc finger-containing protein; Region: zf-C4H2; pfam10146
990282012912	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
990282012913	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
990282012914	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
990282012915	HlyD family secretion protein; Region: HlyD_3; pfam13437
990282012916	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
990282012917	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012918	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012919	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012920	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012921	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012922	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
990282012923	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
990282012924	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012925	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
990282012926	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
990282012927	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012928	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
990282012929	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012930	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
990282012931	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
990282012932	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012933	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
990282012934	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012935	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
990282012936	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
990282012937	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012938	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
990282012939	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
990282012940	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012941	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
990282012942	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012943	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012944	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
990282012945	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012946	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012947	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012948	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012949	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012950	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
990282012951	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012952	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
990282012953	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012954	Bacterial Ig-like domain (group 3); Region: Big_3_2; pfam12245
990282012955	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012956	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
990282012957	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
990282012958	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282012959	Walker A/P-loop; other site
990282012960	ATP binding site [chemical binding]; other site
990282012961	Q-loop/lid; other site
990282012962	ABC transporter signature motif; other site
990282012963	Walker B; other site
990282012964	D-loop; other site
990282012965	H-loop/switch region; other site
990282012966	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
990282012967	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
990282012968	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
990282012969	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
990282012970	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282012971	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
990282012972	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
990282012973	DNA binding residues [nucleotide binding]
990282012974	dimer interface [polypeptide binding]; other site
990282012975	[2Fe-2S] cluster binding site [ion binding]; other site
990282012976	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
990282012977	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
990282012978	putative C-terminal domain interface [polypeptide binding]; other site
990282012979	putative GSH binding site (G-site) [chemical binding]; other site
990282012980	putative dimer interface [polypeptide binding]; other site
990282012981	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
990282012982	putative N-terminal domain interface [polypeptide binding]; other site
990282012983	putative dimer interface [polypeptide binding]; other site
990282012984	putative substrate binding pocket (H-site) [chemical binding]; other site
990282012985	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
990282012986	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
990282012987	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
990282012988	Transcriptional regulator [Transcription]; Region: LysR; COG0583
990282012989	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282012990	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
990282012991	putative dimerization interface [polypeptide binding]; other site
990282012992	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
990282012993	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
990282012994	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
990282012995	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
990282012996	Na binding site [ion binding]; other site
990282012997	Predicted membrane protein [Function unknown]; Region: COG3162
990282012998	acetyl-CoA synthetase; Provisional; Region: PRK00174
990282012999	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
990282013000	active site
990282013001	CoA binding site [chemical binding]; other site
990282013002	acyl-activating enzyme (AAE) consensus motif; other site
990282013003	AMP binding site [chemical binding]; other site
990282013004	acetate binding site [chemical binding]; other site
990282013005	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
990282013006	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
990282013007	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
990282013008	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
990282013009	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
990282013010	heme lyase subunit NrfE; Provisional; Region: PRK10369
990282013011	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
990282013012	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
990282013013	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
990282013014	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
990282013015	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
990282013016	Sel1-like repeats; Region: SEL1; smart00671
990282013017	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
990282013018	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282013019	Coenzyme A binding pocket [chemical binding]; other site
990282013020	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
990282013021	dimer interface [polypeptide binding]; other site
990282013022	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
990282013023	hypothetical protein; Provisional; Region: PRK10220
990282013024	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
990282013025	PhnA protein; Region: PhnA; pfam03831
990282013026	proline/glycine betaine transporter; Provisional; Region: PRK10642
990282013027	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282013028	putative substrate translocation pore; other site
990282013029	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
990282013030	sensor protein BasS/PmrB; Provisional; Region: PRK10755
990282013031	HAMP domain; Region: HAMP; pfam00672
990282013032	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282013033	dimer interface [polypeptide binding]; other site
990282013034	phosphorylation site [posttranslational modification]
990282013035	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282013036	ATP binding site [chemical binding]; other site
990282013037	Mg2+ binding site [ion binding]; other site
990282013038	G-X-G motif; other site
990282013039	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
990282013040	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282013041	active site
990282013042	phosphorylation site [posttranslational modification]
990282013043	intermolecular recognition site; other site
990282013044	dimerization interface [polypeptide binding]; other site
990282013045	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
990282013046	DNA binding site [nucleotide binding]
990282013047	putative metal dependent hydrolase; Provisional; Region: PRK11598
990282013048	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
990282013049	Sulfatase; Region: Sulfatase; pfam00884
990282013050	arginine:agmatin antiporter; Provisional; Region: PRK10644
990282013051	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
990282013052	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282013053	arginine decarboxylase; Provisional; Region: PRK15029
990282013054	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
990282013055	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
990282013056	homodimer interface [polypeptide binding]; other site
990282013057	pyridoxal 5'-phosphate binding site [chemical binding]; other site
990282013058	catalytic residue [active]
990282013059	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
990282013060	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
990282013061	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282013062	alpha-galactosidase; Provisional; Region: PRK15076
990282013063	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
990282013064	NAD binding site [chemical binding]; other site
990282013065	sugar binding site [chemical binding]; other site
990282013066	divalent metal binding site [ion binding]; other site
990282013067	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
990282013068	dimer interface [polypeptide binding]; other site
990282013069	melibiose:sodium symporter; Provisional; Region: PRK10429
990282013070	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
990282013071	fumarate hydratase; Provisional; Region: PRK15389
990282013072	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
990282013073	Fumarase C-terminus; Region: Fumerase_C; pfam05683
990282013074	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
990282013075	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
990282013076	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
990282013077	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282013078	active site
990282013079	phosphorylation site [posttranslational modification]
990282013080	intermolecular recognition site; other site
990282013081	dimerization interface [polypeptide binding]; other site
990282013082	sensory histidine kinase DcuS; Provisional; Region: PRK11086
990282013083	PAS domain; Region: PAS; smart00091
990282013084	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282013085	ATP binding site [chemical binding]; other site
990282013086	Mg2+ binding site [ion binding]; other site
990282013087	G-X-G motif; other site
990282013088	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
990282013089	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
990282013090	putative [Fe4-S4] binding site [ion binding]; other site
990282013091	putative molybdopterin cofactor binding site [chemical binding]; other site
990282013092	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
990282013093	putative molybdopterin cofactor binding site; other site
990282013094	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
990282013095	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
990282013096	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
990282013097	Domain of unknown function (DUF1996); Region: DUF1996; pfam09362
990282013098	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
990282013099	SdiA-regulated; Region: SdiA-regulated; cd09971
990282013100	putative active site [active]
990282013101	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
990282013102	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282013103	DNA binding residues [nucleotide binding]
990282013104	dimerization interface [polypeptide binding]; other site
990282013105	AraC family transcriptional regulator; Provisional; Region: PRK15186
990282013106	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282013107	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
990282013108	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282013109	Coenzyme A binding pocket [chemical binding]; other site
990282013110	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
990282013111	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
990282013112	active site
990282013113	EthD domain; Region: EthD; pfam07110
990282013114	Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily; Region: HTH_MerR-like_sg3; cd01282
990282013115	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
990282013116	DNA binding residues [nucleotide binding]
990282013117	putative dimer interface [polypeptide binding]; other site
990282013118	putative transcriptional regulator; Provisional; Region: PRK11640
990282013119	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
990282013120	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
990282013121	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
990282013122	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
990282013123	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
990282013124	DsbD alpha interface [polypeptide binding]; other site
990282013125	catalytic residues [active]
990282013126	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
990282013127	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
990282013128	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
990282013129	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
990282013130	Aspartase; Region: Aspartase; cd01357
990282013131	active sites [active]
990282013132	tetramer interface [polypeptide binding]; other site
990282013133	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
990282013134	putative transporter; Provisional; Region: PRK11021
990282013135	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
990282013136	oligomerisation interface [polypeptide binding]; other site
990282013137	mobile loop; other site
990282013138	roof hairpin; other site
990282013139	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
990282013140	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
990282013141	ring oligomerisation interface [polypeptide binding]; other site
990282013142	ATP/Mg binding site [chemical binding]; other site
990282013143	stacking interactions; other site
990282013144	hinge regions; other site
990282013145	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
990282013146	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
990282013147	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282013148	FeS/SAM binding site; other site
990282013149	elongation factor P; Validated; Region: PRK00529
990282013150	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
990282013151	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
990282013152	RNA binding site [nucleotide binding]; other site
990282013153	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
990282013154	RNA binding site [nucleotide binding]; other site
990282013155	Predicted small secreted protein [Function unknown]; Region: COG5510
990282013156	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
990282013157	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
990282013158	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282013159	DNA binding residues [nucleotide binding]
990282013160	dimerization interface [polypeptide binding]; other site
990282013161	multidrug efflux system protein; Provisional; Region: PRK11431
990282013162	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
990282013163	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
990282013164	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
990282013165	Iron-sulfur protein interface; other site
990282013166	proximal quinone binding site [chemical binding]; other site
990282013167	C-subunit interface; other site
990282013168	distal quinone binding site; other site
990282013169	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
990282013170	D-subunit interface [polypeptide binding]; other site
990282013171	Iron-sulfur protein interface; other site
990282013172	proximal quinone binding site [chemical binding]; other site
990282013173	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
990282013174	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
990282013175	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
990282013176	L-aspartate oxidase; Provisional; Region: PRK06175
990282013177	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
990282013178	poxB regulator PoxA; Provisional; Region: PRK09350
990282013179	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
990282013180	motif 1; other site
990282013181	dimer interface [polypeptide binding]; other site
990282013182	active site
990282013183	motif 2; other site
990282013184	motif 3; other site
990282013185	inner membrane transporter YjeM; Provisional; Region: PRK15238
990282013186	Protein of unknown function (DUF2645); Region: DUF2645; pfam10840
990282013187	putative mechanosensitive channel protein; Provisional; Region: PRK10929
990282013188	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
990282013189	Mechanosensitive ion channel; Region: MS_channel; pfam00924
990282013190	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
990282013191	GTPase RsgA; Reviewed; Region: PRK12288
990282013192	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
990282013193	RNA binding site [nucleotide binding]; other site
990282013194	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
990282013195	GTPase/Zn-binding domain interface [polypeptide binding]; other site
990282013196	GTP/Mg2+ binding site [chemical binding]; other site
990282013197	G4 box; other site
990282013198	G5 box; other site
990282013199	G1 box; other site
990282013200	Switch I region; other site
990282013201	G2 box; other site
990282013202	G3 box; other site
990282013203	Switch II region; other site
990282013204	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
990282013205	catalytic site [active]
990282013206	putative active site [active]
990282013207	putative substrate binding site [chemical binding]; other site
990282013208	dimer interface [polypeptide binding]; other site
990282013209	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
990282013210	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
990282013211	substrate binding pocket [chemical binding]; other site
990282013212	membrane-bound complex binding site; other site
990282013213	hinge residues; other site
990282013214	epoxyqueuosine reductase; Region: TIGR00276
990282013215	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
990282013216	putative carbohydrate kinase; Provisional; Region: PRK10565
990282013217	Uncharacterized conserved protein [Function unknown]; Region: COG0062
990282013218	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
990282013219	putative substrate binding site [chemical binding]; other site
990282013220	putative ATP binding site [chemical binding]; other site
990282013221	ADP-binding protein; Provisional; Region: PRK10646
990282013222	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
990282013223	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
990282013224	active site
990282013225	metal binding site [ion binding]; metal-binding site
990282013226	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
990282013227	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282013228	ATP binding site [chemical binding]; other site
990282013229	Mg2+ binding site [ion binding]; other site
990282013230	G-X-G motif; other site
990282013231	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
990282013232	ATP binding site [chemical binding]; other site
990282013233	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
990282013234	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
990282013235	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
990282013236	bacterial Hfq-like; Region: Hfq; cd01716
990282013237	hexamer interface [polypeptide binding]; other site
990282013238	Sm1 motif; other site
990282013239	RNA binding site [nucleotide binding]; other site
990282013240	Sm2 motif; other site
990282013241	GTPase HflX; Provisional; Region: PRK11058
990282013242	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
990282013243	HflX GTPase family; Region: HflX; cd01878
990282013244	G1 box; other site
990282013245	GTP/Mg2+ binding site [chemical binding]; other site
990282013246	Switch I region; other site
990282013247	G2 box; other site
990282013248	G3 box; other site
990282013249	Switch II region; other site
990282013250	G4 box; other site
990282013251	G5 box; other site
990282013252	FtsH protease regulator HflK; Provisional; Region: PRK10930
990282013253	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
990282013254	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
990282013255	FtsH protease regulator HflC; Provisional; Region: PRK11029
990282013256	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
990282013257	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
990282013258	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
990282013259	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
990282013260	GDP-binding site [chemical binding]; other site
990282013261	ACT binding site; other site
990282013262	IMP binding site; other site
990282013263	Predicted transcriptional regulator [Transcription]; Region: COG1959
990282013264	transcriptional repressor NsrR; Provisional; Region: PRK11014
990282013265	exoribonuclease R; Provisional; Region: PRK11642
990282013266	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
990282013267	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
990282013268	RNB domain; Region: RNB; pfam00773
990282013269	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
990282013270	RNA binding site [nucleotide binding]; other site
990282013271	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
990282013272	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
990282013273	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
990282013274	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3789
990282013275	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
990282013276	Ion channel; Region: Ion_trans_2; pfam07885
990282013277	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
990282013278	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
990282013279	Predicted membrane protein [Function unknown]; Region: COG3766
990282013280	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
990282013281	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
990282013282	Predicted integral membrane protein [Function unknown]; Region: COG5463
990282013283	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
990282013284	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
990282013285	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
990282013286	FAD binding site [chemical binding]; other site
990282013287	substrate binding site [chemical binding]; other site
990282013288	catalytic residues [active]
990282013289	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
990282013290	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
990282013291	esterase; Provisional; Region: PRK10566
990282013292	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
990282013293	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
990282013294	transcriptional repressor UlaR; Provisional; Region: PRK13509
990282013295	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
990282013296	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
990282013297	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
990282013298	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
990282013299	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
990282013300	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
990282013301	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
990282013302	active site
990282013303	P-loop; other site
990282013304	phosphorylation site [posttranslational modification]
990282013305	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
990282013306	active site
990282013307	phosphorylation site [posttranslational modification]
990282013308	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
990282013309	active site
990282013310	dimer interface [polypeptide binding]; other site
990282013311	magnesium binding site [ion binding]; other site
990282013312	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
990282013313	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
990282013314	AP (apurinic/apyrimidinic) site pocket; other site
990282013315	DNA interaction; other site
990282013316	Metal-binding active site; metal-binding site
990282013317	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
990282013318	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
990282013319	intersubunit interface [polypeptide binding]; other site
990282013320	active site
990282013321	Zn2+ binding site [ion binding]; other site
990282013322	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
990282013323	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
990282013324	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
990282013325	dimer interface [polypeptide binding]; other site
990282013326	ssDNA binding site [nucleotide binding]; other site
990282013327	tetramer (dimer of dimers) interface [polypeptide binding]; other site
990282013328	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
990282013329	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
990282013330	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
990282013331	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
990282013332	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
990282013333	EamA-like transporter family; Region: EamA; pfam00892
990282013334	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
990282013335	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
990282013336	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
990282013337	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
990282013338	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
990282013339	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
990282013340	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
990282013341	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
990282013342	Hemerythrin-like domain; Region: Hr-like; cd12108
990282013343	Fe binding site [ion binding]; other site
990282013344	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
990282013345	EamA-like transporter family; Region: EamA; pfam00892
990282013346	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
990282013347	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
990282013348	NADP binding site [chemical binding]; other site
990282013349	Predicted transcriptional regulators [Transcription]; Region: COG1733
990282013350	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
990282013351	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
990282013352	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
990282013353	active site
990282013354	metal binding site [ion binding]; metal-binding site
990282013355	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
990282013356	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
990282013357	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
990282013358	active site
990282013359	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
990282013360	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
990282013361	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
990282013362	Domain of unknown function DUF21; Region: DUF21; pfam01595
990282013363	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
990282013364	Transporter associated domain; Region: CorC_HlyC; smart01091
990282013365	methionine sulfoxide reductase A; Provisional; Region: PRK00058
990282013366	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
990282013367	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
990282013368	Surface antigen; Region: Bac_surface_Ag; pfam01103
990282013369	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
990282013370	Family of unknown function (DUF490); Region: DUF490; pfam04357
990282013371	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
990282013372	putative active site pocket [active]
990282013373	dimerization interface [polypeptide binding]; other site
990282013374	putative catalytic residue [active]
990282013375	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282013376	D-galactonate transporter; Region: 2A0114; TIGR00893
990282013377	putative substrate translocation pore; other site
990282013378	putative metallo-dependent hydrolase; Provisional; Region: PRK12394
990282013379	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
990282013380	active site
990282013381	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
990282013382	dimer interface [polypeptide binding]; other site
990282013383	substrate binding site [chemical binding]; other site
990282013384	metal binding sites [ion binding]; metal-binding site
990282013385	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
990282013386	AMP binding site [chemical binding]; other site
990282013387	metal binding site [ion binding]; metal-binding site
990282013388	active site
990282013389	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
990282013390	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
990282013391	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
990282013392	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
990282013393	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
990282013394	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
990282013395	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
990282013396	putative active site [active]
990282013397	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
990282013398	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282013399	putative substrate translocation pore; other site
990282013400	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282013401	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
990282013402	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282013403	putative substrate translocation pore; other site
990282013404	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282013405	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
990282013406	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
990282013407	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
990282013408	tetrameric interface [polypeptide binding]; other site
990282013409	NAD binding site [chemical binding]; other site
990282013410	catalytic residues [active]
990282013411	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
990282013412	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
990282013413	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282013414	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
990282013415	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
990282013416	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
990282013417	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
990282013418	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
990282013419	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
990282013420	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
990282013421	major facilitator superfamily transporter; Provisional; Region: PRK05122
990282013422	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282013423	putative substrate translocation pore; other site
990282013424	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
990282013425	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
990282013426	substrate binding site [chemical binding]; other site
990282013427	ATP binding site [chemical binding]; other site
990282013428	Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863
990282013429	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892
990282013430	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
990282013431	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
990282013432	PYR/PP interface [polypeptide binding]; other site
990282013433	dimer interface [polypeptide binding]; other site
990282013434	TPP binding site [chemical binding]; other site
990282013435	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
990282013436	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
990282013437	TPP-binding site; other site
990282013438	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
990282013439	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
990282013440	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
990282013441	polyol permease family; Region: 2A0118; TIGR00897
990282013442	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282013443	putative substrate translocation pore; other site
990282013444	Predicted sugar epimerase [Carbohydrate transport and metabolism]; Region: COG4130
990282013445	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
990282013446	DNA interaction; other site
990282013447	Metal-binding active site; metal-binding site
990282013448	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
990282013449	hypothetical protein; Provisional; Region: PRK05255
990282013450	peptidase PmbA; Provisional; Region: PRK11040
990282013451	cytochrome b562; Provisional; Region: PRK15058
990282013452	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
990282013453	conserved hypothetical protein EF_0830/AHA_3911; Region: EF_0830; TIGR03577
990282013454	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
990282013455	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
990282013456	conserved hypothetical protein EF_0833/AHA_3914; Region: EF_0833; TIGR03579
990282013457	probable amidohydrolase EF_0837/AHA_3915; Region: EF_0837; TIGR03583
990282013458	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
990282013459	active site
990282013460	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
990282013461	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
990282013462	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
990282013463	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
990282013464	HTH domain; Region: HTH_11; pfam08279
990282013465	Mga helix-turn-helix domain; Region: Mga; pfam05043
990282013466	PRD domain; Region: PRD; pfam00874
990282013467	PRD domain; Region: PRD; pfam00874
990282013468	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
990282013469	active site
990282013470	P-loop; other site
990282013471	phosphorylation site [posttranslational modification]
990282013472	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
990282013473	active site
990282013474	phosphorylation site [posttranslational modification]
990282013475	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
990282013476	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
990282013477	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
990282013478	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282013479	FeS/SAM binding site; other site
990282013480	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
990282013481	ATP cone domain; Region: ATP-cone; pfam03477
990282013482	Class III ribonucleotide reductase; Region: RNR_III; cd01675
990282013483	effector binding site; other site
990282013484	active site
990282013485	Zn binding site [ion binding]; other site
990282013486	glycine loop; other site
990282013487	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
990282013488	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
990282013489	Ca binding site [ion binding]; other site
990282013490	active site
990282013491	catalytic site [active]
990282013492	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
990282013493	trehalose repressor; Provisional; Region: treR; PRK09492
990282013494	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
990282013495	DNA binding site [nucleotide binding]
990282013496	domain linker motif; other site
990282013497	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
990282013498	dimerization interface [polypeptide binding]; other site
990282013499	ligand binding site [chemical binding]; other site
990282013500	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
990282013501	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
990282013502	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
990282013503	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
990282013504	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
990282013505	Soluble P-type ATPase [General function prediction only]; Region: COG4087
990282013506	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
990282013507	Transposase; Region: HTH_Tnp_1; cl17663
990282013508	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
990282013509	homotrimer interaction site [polypeptide binding]; other site
990282013510	putative active site [active]
990282013511	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
990282013512	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
990282013513	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
990282013514	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
990282013515	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
990282013516	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
990282013517	pyrBI operon leader peptide; Provisional; Region: PRK10224
990282013518	Arginine repressor [Transcription]; Region: ArgR; COG1438
990282013519	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
990282013520	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
990282013521	Predicted membrane protein [Function unknown]; Region: COG1288
990282013522	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
990282013523	ornithine carbamoyltransferase; Validated; Region: PRK02102
990282013524	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
990282013525	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
990282013526	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
990282013527	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
990282013528	putative substrate binding site [chemical binding]; other site
990282013529	nucleotide binding site [chemical binding]; other site
990282013530	nucleotide binding site [chemical binding]; other site
990282013531	homodimer interface [polypeptide binding]; other site
990282013532	arginine deiminase; Provisional; Region: PRK01388
990282013533	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
990282013534	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
990282013535	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
990282013536	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
990282013537	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
990282013538	RNase E inhibitor protein; Provisional; Region: PRK11191
990282013539	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
990282013540	active site
990282013541	dinuclear metal binding site [ion binding]; other site
990282013542	dimerization interface [polypeptide binding]; other site
990282013543	Protein of unknown function (DUF3617); Region: DUF3617; pfam12276
990282013544	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
990282013545	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282013546	Coenzyme A binding pocket [chemical binding]; other site
990282013547	Predicted membrane protein [Function unknown]; Region: COG4269
990282013548	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
990282013549	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
990282013550	HIGH motif; other site
990282013551	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
990282013552	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
990282013553	active site
990282013554	KMSKS motif; other site
990282013555	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
990282013556	tRNA binding surface [nucleotide binding]; other site
990282013557	anticodon binding site; other site
990282013558	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
990282013559	DNA polymerase III subunit chi; Validated; Region: PRK05728
990282013560	multifunctional aminopeptidase A; Provisional; Region: PRK00913
990282013561	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
990282013562	interface (dimer of trimers) [polypeptide binding]; other site
990282013563	Substrate-binding/catalytic site; other site
990282013564	Zn-binding sites [ion binding]; other site
990282013565	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
990282013566	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
990282013567	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
990282013568	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
990282013569	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
990282013570	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
990282013571	DNA binding site [nucleotide binding]
990282013572	domain linker motif; other site
990282013573	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
990282013574	putative dimerization interface [polypeptide binding]; other site
990282013575	putative ligand binding site [chemical binding]; other site
990282013576	gluconate transporter; Region: gntP; TIGR00791
990282013577	fructuronate transporter; Provisional; Region: PRK10034; cl15264
990282013578	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
990282013579	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
990282013580	NADP binding site [chemical binding]; other site
990282013581	homodimer interface [polypeptide binding]; other site
990282013582	active site
990282013583	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
990282013584	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
990282013585	putative NAD(P) binding site [chemical binding]; other site
990282013586	catalytic Zn binding site [ion binding]; other site
990282013587	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
990282013588	ATP-binding site [chemical binding]; other site
990282013589	Gluconate-6-phosphate binding site [chemical binding]; other site
990282013590	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
990282013591	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
990282013592	putative NAD(P) binding site [chemical binding]; other site
990282013593	putative substrate binding site [chemical binding]; other site
990282013594	catalytic Zn binding site [ion binding]; other site
990282013595	structural Zn binding site [ion binding]; other site
990282013596	dimer interface [polypeptide binding]; other site
990282013597	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
990282013598	Part of AAA domain; Region: AAA_19; pfam13245
990282013599	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
990282013600	AAA domain; Region: AAA_12; pfam13087
990282013601	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
990282013602	putative active site [active]
990282013603	catalytic site [active]
990282013604	Uncharacterized conserved protein [Function unknown]; Region: COG4127
990282013605	Restriction endonuclease; Region: Mrr_cat; pfam04471
990282013606	conserved hypothetical protein; Region: Lon_rel_chp; TIGR02653
990282013607	Putative ATP-dependent Lon protease; Region: Lon_2; pfam13337
990282013608	TIGR02687 family protein; Region: TIGR02687
990282013609	PglZ domain; Region: PglZ; pfam08665
990282013610	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282013611	AAA domain; Region: AAA_21; pfam13304
990282013612	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282013613	Walker A/P-loop; other site
990282013614	Walker A/P-loop; other site
990282013615	ATP binding site [chemical binding]; other site
990282013616	ATP binding site [chemical binding]; other site
990282013617	Q-loop/lid; other site
990282013618	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
990282013619	Methyltransferase domain; Region: Methyltransf_26; pfam13659
990282013620	TIGR02680 family protein; Region: TIGR02680
990282013621	Domain of unknown function (DUF1788); Region: DUF1788; pfam08747
990282013622	Putative inner membrane protein (DUF1819); Region: DUF1819; pfam08849
990282013623	hypothetical protein; Provisional; Region: PRK12378
990282013624	Methyltransferase domain; Region: Methyltransf_23; pfam13489
990282013625	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282013626	S-adenosylmethionine binding site [chemical binding]; other site
990282013627	Methyltransferase domain; Region: Methyltransf_31; pfam13847
990282013628	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282013629	S-adenosylmethionine binding site [chemical binding]; other site
990282013630	hypothetical protein; Provisional; Region: PRK13687
990282013631	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4332
990282013632	Uncharacterized conserved protein [Function unknown]; Region: COG3439
990282013633	Dienelactone hydrolase family; Region: DLH; pfam01738
990282013634	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
990282013635	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
990282013636	DNA-binding site [nucleotide binding]; DNA binding site
990282013637	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
990282013638	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
990282013639	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
990282013640	active site
990282013641	HIGH motif; other site
990282013642	dimer interface [polypeptide binding]; other site
990282013643	KMSKS motif; other site
990282013644	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
990282013645	Aspartate racemase [Cell envelope biogenesis, outer membrane]; Region: RacX; COG1794
990282013646	aspartate racemase; Region: asp_race; TIGR00035
990282013647	cell density-dependent motility repressor; Provisional; Region: PRK10082
990282013648	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282013649	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
990282013650	dimerization interface [polypeptide binding]; other site
990282013651	isoaspartyl dipeptidase; Provisional; Region: PRK10657
990282013652	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
990282013653	active site
990282013654	hypothetical protein; Provisional; Region: PRK10519
990282013655	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
990282013656	Nucleoside recognition; Region: Gate; pfam07670
990282013657	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
990282013658	Predicted membrane protein [Function unknown]; Region: COG2733
990282013659	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
990282013660	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
990282013661	putative substrate translocation pore; other site
990282013662	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
990282013663	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
990282013664	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
990282013665	NAD(P) binding site [chemical binding]; other site
990282013666	catalytic residues [active]
990282013667	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
990282013668	endoribonuclease SymE; Provisional; Region: PRK13605
990282013669	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
990282013670	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
990282013671	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
990282013672	HsdM N-terminal domain; Region: HsdM_N; pfam12161
990282013673	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
990282013674	Methyltransferase domain; Region: Methyltransf_26; pfam13659
990282013675	type I restriction enzyme EcoKI subunit R; Provisional; Region: hsdR; PRK11448
990282013676	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
990282013677	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
990282013678	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
990282013679	ATP binding site [chemical binding]; other site
990282013680	putative Mg++ binding site [ion binding]; other site
990282013681	Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715
990282013682	Mrr N-terminal domain; Region: Mrr_N; pfam14338
990282013683	Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; Region: CH; cl00030
990282013684	Restriction endonuclease; Region: Mrr_cat; pfam04471
990282013685	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2929
990282013686	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3514
990282013687	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
990282013688	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
990282013689	P-loop, Walker A motif; other site
990282013690	Base recognition motif; other site
990282013691	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
990282013692	Uncharacterized small protein [Function unknown]; Region: COG2879
990282013693	carbon starvation protein A; Provisional; Region: PRK15015
990282013694	Carbon starvation protein CstA; Region: CstA; pfam02554
990282013695	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
990282013696	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
990282013697	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
990282013698	dimer interface [polypeptide binding]; other site
990282013699	ligand binding site [chemical binding]; other site
990282013700	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
990282013701	dimerization interface [polypeptide binding]; other site
990282013702	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
990282013703	dimer interface [polypeptide binding]; other site
990282013704	putative CheW interface [polypeptide binding]; other site
990282013705	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
990282013706	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282013707	Walker A motif; other site
990282013708	ATP binding site [chemical binding]; other site
990282013709	Walker B motif; other site
990282013710	arginine finger; other site
990282013711	Transcriptional antiterminator [Transcription]; Region: COG3933
990282013712	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
990282013713	active pocket/dimerization site; other site
990282013714	active site
990282013715	phosphorylation site [posttranslational modification]
990282013716	PRD domain; Region: PRD; pfam00874
990282013717	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
990282013718	active pocket/dimerization site; other site
990282013719	active site
990282013720	phosphorylation site [posttranslational modification]
990282013721	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
990282013722	active site
990282013723	phosphorylation site [posttranslational modification]
990282013724	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
990282013725	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
990282013726	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
990282013727	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
990282013728	dimer interface [polypeptide binding]; other site
990282013729	active site
990282013730	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
990282013731	dimer interface [polypeptide binding]; other site
990282013732	active site
990282013733	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
990282013734	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
990282013735	putative active site [active]
990282013736	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
990282013737	phosphoglycerol transferase I; Provisional; Region: PRK03776
990282013738	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
990282013739	hypothetical protein; Provisional; Region: PRK11667
990282013740	DNA replication protein DnaC; Validated; Region: PRK07952
990282013741	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
990282013742	Walker A motif; other site
990282013743	ATP binding site [chemical binding]; other site
990282013744	Walker B motif; other site
990282013745	primosomal protein DnaI; Provisional; Region: PRK02854
990282013746	hypothetical protein; Provisional; Region: PRK09917
990282013747	Uncharacterized conserved protein [Function unknown]; Region: COG2966
990282013748	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
990282013749	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
990282013750	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282013751	DNA binding residues [nucleotide binding]
990282013752	dimerization interface [polypeptide binding]; other site
990282013753	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
990282013754	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282013755	DNA binding residues [nucleotide binding]
990282013756	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
990282013757	putative deacylase active site [active]
990282013758	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
990282013759	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
990282013760	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
990282013761	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
990282013762	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
990282013763	metal binding site [ion binding]; metal-binding site
990282013764	active site
990282013765	I-site; other site
990282013766	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
990282013767	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
990282013768	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
990282013769	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
990282013770	S-adenosylmethionine binding site [chemical binding]; other site
990282013771	DNA polymerase III subunit psi; Validated; Region: PRK06856
990282013772	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
990282013773	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
990282013774	Coenzyme A binding pocket [chemical binding]; other site
990282013775	dUMP phosphatase; Provisional; Region: PRK09449
990282013776	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282013777	motif II; other site
990282013778	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
990282013779	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
990282013780	G1 box; other site
990282013781	putative GEF interaction site [polypeptide binding]; other site
990282013782	GTP/Mg2+ binding site [chemical binding]; other site
990282013783	Switch I region; other site
990282013784	G2 box; other site
990282013785	G3 box; other site
990282013786	Switch II region; other site
990282013787	G4 box; other site
990282013788	G5 box; other site
990282013789	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
990282013790	periplasmic protein; Provisional; Region: PRK10568
990282013791	BON domain; Region: BON; pfam04972
990282013792	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
990282013793	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
990282013794	active site
990282013795	nucleophile elbow; other site
990282013796	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
990282013797	active site
990282013798	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
990282013799	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
990282013800	FeS/SAM binding site; other site
990282013801	hypothetical protein; Provisional; Region: PRK10977
990282013802	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
990282013803	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
990282013804	intersubunit interface [polypeptide binding]; other site
990282013805	active site
990282013806	catalytic residue [active]
990282013807	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
990282013808	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
990282013809	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
990282013810	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
990282013811	phosphopentomutase; Provisional; Region: PRK05362
990282013812	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
990282013813	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
990282013814	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
990282013815	hypothetical protein; Provisional; Region: PRK15301
990282013816	putative fimbrial outer membrane usher protein; Provisional; Region: PRK15304
990282013817	PapC N-terminal domain; Region: PapC_N; pfam13954
990282013818	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
990282013819	PapC C-terminal domain; Region: PapC_C; pfam13953
990282013820	putative fimbrial chaperone protein; Provisional; Region: PRK09918
990282013821	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
990282013822	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
990282013823	hypothetical protein; Provisional; Region: PRK15302
990282013824	hypothetical protein; Provisional; Region: PRK15303
990282013825	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
990282013826	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
990282013827	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
990282013828	hypothetical protein; Provisional; Region: PRK11246
990282013829	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
990282013830	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
990282013831	motif II; other site
990282013832	DNA repair protein RadA; Region: sms; TIGR00416
990282013833	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
990282013834	Walker A motif/ATP binding site; other site
990282013835	ATP binding site [chemical binding]; other site
990282013836	Walker B motif; other site
990282013837	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
990282013838	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
990282013839	non-specific DNA binding site [nucleotide binding]; other site
990282013840	salt bridge; other site
990282013841	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
990282013842	sequence-specific DNA binding site [nucleotide binding]; other site
990282013843	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
990282013844	active site
990282013845	(T/H)XGH motif; other site
990282013846	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
990282013847	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
990282013848	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
990282013849	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
990282013850	ABC transporter; Region: ABC_tran_2; pfam12848
990282013851	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
990282013852	lytic murein transglycosylase; Provisional; Region: PRK11619
990282013853	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
990282013854	N-acetyl-D-glucosamine binding site [chemical binding]; other site
990282013855	catalytic residue [active]
990282013856	Trp operon repressor; Provisional; Region: PRK01381
990282013857	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
990282013858	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
990282013859	catalytic core [active]
990282013860	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
990282013861	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282013862	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
990282013863	hypothetical protein; Provisional; Region: PRK10756
990282013864	CreA protein; Region: CreA; pfam05981
990282013865	DNA-binding response regulator CreB; Provisional; Region: PRK11083
990282013866	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282013867	active site
990282013868	phosphorylation site [posttranslational modification]
990282013869	intermolecular recognition site; other site
990282013870	dimerization interface [polypeptide binding]; other site
990282013871	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
990282013872	DNA binding site [nucleotide binding]
990282013873	sensory histidine kinase CreC; Provisional; Region: PRK11100
990282013874	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
990282013875	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
990282013876	dimer interface [polypeptide binding]; other site
990282013877	phosphorylation site [posttranslational modification]
990282013878	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
990282013879	ATP binding site [chemical binding]; other site
990282013880	Mg2+ binding site [ion binding]; other site
990282013881	G-X-G motif; other site
990282013882	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
990282013883	putative major fimbrial protein SthE; Provisional; Region: PRK15292
990282013884	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
990282013885	putative fimbrial protein SthD; Provisional; Region: PRK15293
990282013886	putative fimbrial outer membrane usher protein SthC; Provisional; Region: PRK15294
990282013887	PapC N-terminal domain; Region: PapC_N; pfam13954
990282013888	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
990282013889	PapC C-terminal domain; Region: PapC_C; pfam13953
990282013890	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
990282013891	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
990282013892	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
990282013893	putative fimbrial protein SthA; Provisional; Region: PRK15296
990282013894	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
990282013895	Helix-turn-helix domain; Region: HTH_36; pfam13730
990282013896	two-component response regulator; Provisional; Region: PRK11173
990282013897	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
990282013898	active site
990282013899	phosphorylation site [posttranslational modification]
990282013900	intermolecular recognition site; other site
990282013901	dimerization interface [polypeptide binding]; other site
990282013902	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
990282013903	DNA binding site [nucleotide binding]
990282013904	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
990282013905	putative RNA methyltransferase; Provisional; Region: PRK10433
990282013906	plasmid maintenance protein CcdA; Provisional; Region: PRK13710
990282013907	plasmid maintenance protein CcdB; Provisional; Region: PRK13708
990282013908	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
990282013909	active site
990282013910	catalytic residues [active]
990282013911	DNA binding site [nucleotide binding]
990282013912	Int/Topo IB signature motif; other site
990282013913	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
990282013914	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
990282013915	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
990282013916	Transposase IS200 like; Region: Y1_Tnp; pfam01797
990282013917	virulence protein SpvD; Provisional; Region: PRK15250
990282013918	Salmonella virulence-associated 28kDa protein; Region: VRP3; pfam03536
990282013919	virulence protein SpvB; Provisional; Region: PRK15244
990282013920	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
990282013921	VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cl00173
990282013922	active site
990282013923	conformational flexibility of ligand binding pocket; other site
990282013924	ADP-ribosylating toxin turn-turn motif; other site
990282013925	virulence protein SpvA; Provisional; Region: PRK15212
990282013926	transcriptional regulator SpvR; Provisional; Region: PRK15243
990282013927	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
990282013928	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
990282013929	Homeodomain-like domain; Region: HTH_23; pfam13384
990282013930	Winged helix-turn helix; Region: HTH_29; pfam13551
990282013931	Homeodomain-like domain; Region: HTH_32; pfam13565
990282013932	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
990282013933	DDE superfamily endonuclease; Region: DDE_3; pfam13358
990282013934	Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]; Region: ExeA; COG3267
990282013935	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
990282013936	Walker A/P-loop; other site
990282013937	Integrase core domain; Region: rve; pfam00665
990282013938	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
990282013939	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
990282013940	catalytic residues [active]
990282013941	catalytic nucleophile [active]
990282013942	Presynaptic Site I dimer interface [polypeptide binding]; other site
990282013943	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
990282013944	Synaptic Flat tetramer interface [polypeptide binding]; other site
990282013945	Synaptic Site I dimer interface [polypeptide binding]; other site
990282013946	DNA binding site [nucleotide binding]
990282013947	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
990282013948	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
990282013949	active site clefts [active]
990282013950	zinc binding site [ion binding]; other site
990282013951	dimer interface [polypeptide binding]; other site
990282013952	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
990282013953	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
990282013954	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
990282013955	catalytic site [active]
990282013956	Uncharacterized conserved protein [Function unknown]; Region: COG5464
990282013957	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
990282013958	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
990282013959	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
990282013960	P-loop; other site
990282013961	Magnesium ion binding site [ion binding]; other site
990282013962	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
990282013963	Magnesium ion binding site [ion binding]; other site
990282013964	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
990282013965	ParB-like nuclease domain; Region: ParBc; pfam02195
990282013966	ParB family; Region: ParB; pfam08775
990282013967	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
990282013968	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
990282013969	active site
990282013970	DNA binding site [nucleotide binding]
990282013971	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
990282013972	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
990282013973	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
990282013974	Catalytic site [active]
990282013975	putative methylase; Provisional; Region: PRK13699
990282013976	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
990282013977	Antirestriction protein; Region: Antirestrict; pfam03230
990282013978	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
990282013979	DNA polymerase III, theta subunit; Region: DNA_pol3_theta; pfam06440
990282013980	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
990282013981	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
990282013982	dimer interface [polypeptide binding]; other site
990282013983	ssDNA binding site [nucleotide binding]; other site
990282013984	tetramer (dimer of dimers) interface [polypeptide binding]; other site
990282013985	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
990282013986	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
990282013987	ParB-like nuclease domain; Region: ParBc; pfam02195
990282013988	Plasmid SOS inhibition protein (PsiB); Region: PsiB; pfam06290
990282013989	PsiA protein; Region: PsiA; pfam06952
990282013990	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
990282013991	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
990282013992	N-acetyl-D-glucosamine binding site [chemical binding]; other site
990282013993	catalytic residue [active]
990282013994	conjugal transfer protein TraM; Provisional; Region: PRK13713
990282013995	conjugal transfer transcriptional regulator TraJ; Provisional; Region: PRK13719
990282013996	conjugal transfer protein TraY; Provisional; Region: PRK13740
990282013997	conjugal transfer pilin subunit TraA; Provisional; Region: PRK13734
990282013998	conjugal transfer pilus assembly protein TraL; Provisional; Region: PRK13707
990282013999	conjugal transfer pilus assembly protein TraE; Provisional; Region: PRK13726
990282014000	conjugal transfer protein TraK; Provisional; Region: PRK13736
990282014001	TraK protein; Region: TraK; pfam06586
990282014002	conjugal transfer pilus assembly protein TraB; Provisional; Region: PRK13729
990282014003	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
990282014004	TraP protein; Region: TraP; pfam07296
990282014005	conjugal transfer protein TrbD; Provisional; Region: PRK13724
990282014006	NTPase; Region: NTPase_1; cl17478
990282014007	conjugal transfer protein TraV; Provisional; Region: PRK13733
990282014008	Type IV conjugative transfer system lipoprotein (TraV); Region: TraV; pfam09676
990282014009	conjugal transfer protein TraR; Provisional; Region: PRK13715
990282014010	conjugal transfer ATP-binding protein TraC; Provisional; Region: PRK13721
990282014011	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
990282014012	Domain of unknown function DUF87; Region: DUF87; pfam01935
990282014013	conjugal transfer protein TrbI; Provisional; Region: PRK13717
990282014014	conjugal transfer pilus assembly protein TraW; Provisional; Region: PRK13738
990282014015	conjugal transfer pilus assembly protein TraU; Provisional; Region: PRK13737
990282014016	conjugal transfer pilus assembly protein TrbC; Provisional; Region: PRK13730
990282014017	conjugal transfer mating pair stabilization protein TraN; Reviewed; Region: PRK12355
990282014018	conjugal transfer protein TrbE; Provisional; Region: PRK13718
990282014019	conjugal pilus assembly protein TraF; Provisional; Region: PRK13703
990282014020	F plasmid transfer operon protein; Region: TraF; pfam13728
990282014021	conjugal transfer pilin chaperone TraQ; Provisional; Region: PRK13727
990282014022	conjugal transfer protein TrbB; Provisional; Region: PRK13728
990282014023	conjugal transfer pilus assembly protein TraH; Provisional; Region: PRK13723
990282014024	conjugal transfer mating pair stabilization protein TraG; Provisional; Region: PRK13735
990282014025	Plasmid conjugative transfer entry exclusion protein TraS; Region: TraS; pfam10624
990282014026	conjugal transfer surface exclusion protein TraT; Provisional; Region: PRK13731
990282014027	Enterobacterial TraT complement resistance protein; Region: TraT; pfam05818
990282014028	conjugal transfer protein TraD; Provisional; Region: PRK13700
990282014029	F sex factor protein N terminal; Region: TraD_N; pfam12615
990282014030	Bacterial conjugation protein TrwB,  ATP binding domain. TrwB is a homohexamer encoded by conjugative plasmids in Gram-negative bacteria. TrwB also has an all alpha domain which has been hypothesized to be responsible for DNA binding. TrwB is a component...; Region: TrwB; cd01127
990282014031	multimer interface [polypeptide binding]; other site
990282014032	Walker A motif; other site
990282014033	ATP binding site [chemical binding]; other site
990282014034	Walker B motif; other site
990282014035	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
990282014036	oligomeric interface; other site
990282014037	putative active site [active]
990282014038	homodimer interface [polypeptide binding]; other site
990282014039	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
990282014040	conjugal transfer nickase/helicase TraI; Provisional; Region: PRK13709
990282014041	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
990282014042	AAA domain; Region: AAA_30; pfam13604
990282014043	DNA helicase TraI; Region: TraI; pfam07057
990282014044	conjugal transfer pilus acetylation protein TraX; Provisional; Region: PRK13706
990282014045	conjugal transfer fertility inhibition protein FinO; Provisional; Region: PRK13754
990282014046	Fertility inhibition protein N terminal; Region: FinO_N; pfam12602
990282014047	FinO bacterial conjugation repressor domain;  the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which...; Region: FinO_conjug_rep; cd00236
990282014048	putative kissing complex interaction region; other site
990282014049	putative RNA binding sites [nucleotide binding]; other site
990282014050	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
990282014051	replication protein; Provisional; Region: PRK13702
990282014052	RepA leader peptide Tap; Provisional; Region: PRK14745
990282014053	replication protein; Provisional; Region: PRK13750
990282014054	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
990282014055	SdiA-regulated; Region: SdiA-regulated; cd09971
990282014056	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
990282014057	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
990282014058	resistance to complement killing; Provisional; Region: PRK15240
990282014059	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
990282014060	SdiA-regulated; Region: SdiA-regulated; cd09971
990282014061	putative active site [active]
990282014062	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
990282014063	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
990282014064	catalytic residues [active]
990282014065	hinge region; other site
990282014066	alpha helical domain; other site
990282014067	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
990282014068	DNA binding residues [nucleotide binding]
990282014069	dimerization interface [polypeptide binding]; other site
990282014070	FaeA-like protein; Region: FaeA; pfam04703
990282014071	fimbrial chaperone protein PefD; Provisional; Region: PRK15211
990282014072	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
990282014073	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
990282014074	fimbrial outer membrane usher protein PefC; Provisional; Region: PRK15213
990282014075	PapC N-terminal domain; Region: PapC_N; pfam13954
990282014076	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
990282014077	fimbrial protein PefA; Provisional; Region: PRK15214
990282014078	Adhesin biosynthesis transcription regulatory protein; Region: PapB; pfam03333
990282014079	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111