-- dump date   	20140620_061741
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
85569000001	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
85569000002	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
85569000003	putative catalytic residues [active]
85569000004	putative nucleotide binding site [chemical binding]; other site
85569000005	putative aspartate binding site [chemical binding]; other site
85569000006	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
85569000007	dimer interface [polypeptide binding]; other site
85569000008	putative threonine allosteric regulatory site; other site
85569000009	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
85569000010	putative threonine allosteric regulatory site; other site
85569000011	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
85569000012	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
85569000013	homoserine kinase; Provisional; Region: PRK01212
85569000014	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
85569000015	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
85569000016	threonine synthase; Validated; Region: PRK09225
85569000017	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
85569000018	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
85569000019	catalytic residue [active]
85569000020	hypothetical protein; Validated; Region: PRK02101
85569000021	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
85569000022	transaldolase-like protein; Provisional; Region: PTZ00411
85569000023	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
85569000024	active site
85569000025	dimer interface [polypeptide binding]; other site
85569000026	catalytic residue [active]
85569000027	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
85569000028	MPT binding site; other site
85569000029	trimer interface [polypeptide binding]; other site
85569000030	hypothetical protein; Provisional; Region: PRK10659
85569000031	hypothetical protein; Provisional; Region: PRK10236
85569000032	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
85569000033	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
85569000034	Protein of unknown function (DUF2541); Region: DUF2541; pfam10807
85569000035	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
85569000036	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
85569000037	nucleotide binding site [chemical binding]; other site
85569000038	NEF interaction site [polypeptide binding]; other site
85569000039	SBD interface [polypeptide binding]; other site
85569000040	chaperone protein DnaJ; Provisional; Region: PRK10767
85569000041	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
85569000042	HSP70 interaction site [polypeptide binding]; other site
85569000043	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
85569000044	substrate binding site [polypeptide binding]; other site
85569000045	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
85569000046	Zn binding sites [ion binding]; other site
85569000047	dimer interface [polypeptide binding]; other site
85569000048	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569000049	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569000050	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
85569000051	dimerization interface [polypeptide binding]; other site
85569000052	Lysozyme family protein [General function prediction only]; Region: zliS; COG3926
85569000053	Glycosyl hydrolase 108; Region: Glyco_hydro_108; pfam05838
85569000054	Predicted Peptidoglycan domain; Region: PG_binding_3; pfam09374
85569000055	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
85569000056	Chitinase [Carbohydrate transport and metabolism]; Region: ChiA; COG3325
85569000057	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
85569000058	active site
85569000059	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
85569000060	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
85569000061	aromatic chitin/cellulose binding site residues [chemical binding]; other site
85569000062	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
85569000063	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
85569000064	fimbrial protein BcfA; Provisional; Region: PRK15187
85569000065	fimbrial chaperone protein BcfB; Provisional; Region: PRK15188
85569000066	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
85569000067	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
85569000068	outer membrane usher protein; Provisional; Region: PRK15193
85569000069	PapC N-terminal domain; Region: PapC_N; pfam13954
85569000070	Outer membrane usher protein; Region: Usher; pfam00577
85569000071	PapC C-terminal domain; Region: PapC_C; pfam13953
85569000072	fimbrial protein BcfD; Provisional; Region: PRK15189
85569000073	fimbrial protein BcfE; Provisional; Region: PRK15190
85569000074	fimbrial protein BcfF; Provisional; Region: PRK15191
85569000075	fimbrial chaperone BcfG; Provisional; Region: PRK15192
85569000076	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
85569000077	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
85569000078	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
85569000079	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
85569000080	catalytic residues [active]
85569000081	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
85569000082	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569000083	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569000084	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
85569000085	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
85569000086	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
85569000087	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
85569000088	active site
85569000089	metal binding site [ion binding]; metal-binding site
85569000090	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
85569000091	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; pfam03502
85569000092	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
85569000093	Sulfatase; Region: Sulfatase; pfam00884
85569000094	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
85569000095	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569000096	FeS/SAM binding site; other site
85569000097	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
85569000098	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
85569000099	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
85569000100	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
85569000101	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
85569000102	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569000103	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
85569000104	putative dimerization interface [polypeptide binding]; other site
85569000105	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
85569000106	Glycosyl hydrolases family 31; Region: Glyco_hydro_31; pfam01055
85569000107	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
85569000108	putative active site [active]
85569000109	putative catalytic site [active]
85569000110	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
85569000111	putative symporter YagG; Provisional; Region: PRK09669; cl15392
85569000112	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
85569000113	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
85569000114	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
85569000115	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
85569000116	active site
85569000117	Riboflavin kinase; Region: Flavokinase; smart00904
85569000118	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
85569000119	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
85569000120	active site
85569000121	HIGH motif; other site
85569000122	KMSKS motif; other site
85569000123	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
85569000124	tRNA binding surface [nucleotide binding]; other site
85569000125	anticodon binding site; other site
85569000126	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
85569000127	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
85569000128	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
85569000129	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
85569000130	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Region: lytB_ispH; cd13944
85569000131	Fe-S cluster binding site [ion binding]; other site
85569000132	substrate binding site [chemical binding]; other site
85569000133	catalytic site [active]
85569000134	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
85569000135	active site
85569000136	tetramer interface [polypeptide binding]; other site
85569000137	Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms]; Region: CitB; COG4565
85569000138	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569000139	active site
85569000140	phosphorylation site [posttranslational modification]
85569000141	intermolecular recognition site; other site
85569000142	dimerization interface [polypeptide binding]; other site
85569000143	Transcriptional regulator; Region: CitT; pfam12431
85569000144	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
85569000145	Sensory domain of two-component sensor kinase; Region: Cache_3; pfam14827
85569000146	PAS domain; Region: PAS; smart00091
85569000147	Sensor_kinase_SpoOB-type, alpha-helical domain; Region: SPOB_a; pfam14689
85569000148	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569000149	ATP binding site [chemical binding]; other site
85569000150	Mg2+ binding site [ion binding]; other site
85569000151	G-X-G motif; other site
85569000152	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15477
85569000153	Na+/citrate symporter [Energy production and conversion]; Region: CitS; COG3493
85569000154	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
85569000155	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
85569000156	putative active site [active]
85569000157	(T/H)XGH motif; other site
85569000158	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
85569000159	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
85569000160	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
85569000161	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
85569000162	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
85569000163	triphosphoribosyl-dephospho-CoA synthase CitG; Region: citrate_citG; TIGR03125
85569000164	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
85569000165	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
85569000166	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
85569000167	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
85569000168	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
85569000169	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
85569000170	catalytic site [active]
85569000171	subunit interface [polypeptide binding]; other site
85569000172	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
85569000173	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
85569000174	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
85569000175	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; smart01096
85569000176	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
85569000177	ATP-grasp domain; Region: ATP-grasp_4; cl17255
85569000178	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
85569000179	IMP binding site; other site
85569000180	dimer interface [polypeptide binding]; other site
85569000181	interdomain contacts; other site
85569000182	partial ornithine binding site; other site
85569000183	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
85569000184	carnitine operon protein CaiE; Provisional; Region: PRK13627
85569000185	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
85569000186	putative trimer interface [polypeptide binding]; other site
85569000187	putative metal binding site [ion binding]; other site
85569000188	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
85569000189	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
85569000190	substrate binding site [chemical binding]; other site
85569000191	oxyanion hole (OAH) forming residues; other site
85569000192	trimer interface [polypeptide binding]; other site
85569000193	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
85569000194	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
85569000195	acyl-activating enzyme (AAE) consensus motif; other site
85569000196	putative AMP binding site [chemical binding]; other site
85569000197	putative active site [active]
85569000198	putative CoA binding site [chemical binding]; other site
85569000199	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
85569000200	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
85569000201	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
85569000202	active site
85569000203	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
85569000204	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
85569000205	Ligand binding site [chemical binding]; other site
85569000206	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
85569000207	Electron transfer flavoprotein domain; Region: ETF; pfam01012
85569000208	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
85569000209	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569000210	putative oxidoreductase FixC; Provisional; Region: PRK10157
85569000211	ferredoxin-like protein FixX; Provisional; Region: PRK15449
85569000212	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569000213	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
85569000214	putative substrate translocation pore; other site
85569000215	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
85569000216	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
85569000217	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
85569000218	Sulfatase; Region: Sulfatase; cl19157
85569000219	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
85569000220	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
85569000221	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
85569000222	TrkA-N domain; Region: TrkA_N; pfam02254
85569000223	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
85569000224	folate binding site [chemical binding]; other site
85569000225	NADP+ binding site [chemical binding]; other site
85569000226	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
85569000227	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
85569000228	active site
85569000229	metal binding site [ion binding]; metal-binding site
85569000230	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
85569000231	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
85569000232	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
85569000233	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
85569000234	SurA N-terminal domain; Region: SurA_N; pfam09312
85569000235	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
85569000236	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
85569000237	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
85569000238	OstA-like protein; Region: OstA; pfam03968
85569000239	Organic solvent tolerance protein; Region: OstA_C; pfam04453
85569000240	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
85569000241	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
85569000242	putative metal binding site [ion binding]; other site
85569000243	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
85569000244	HSP70 interaction site [polypeptide binding]; other site
85569000245	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
85569000246	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
85569000247	active site
85569000248	ATP-dependent helicase HepA; Validated; Region: PRK04914
85569000249	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
85569000250	ATP binding site [chemical binding]; other site
85569000251	putative Mg++ binding site [ion binding]; other site
85569000252	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
85569000253	nucleotide binding region [chemical binding]; other site
85569000254	ATP-binding site [chemical binding]; other site
85569000255	RNA polymerase recycling family C-terminal; Region: RapA_C; pfam12137
85569000256	DNA polymerase II; Reviewed; Region: PRK05762
85569000257	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
85569000258	active site
85569000259	catalytic site [active]
85569000260	substrate binding site [chemical binding]; other site
85569000261	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
85569000262	active site
85569000263	metal-binding site
85569000264	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
85569000265	putative active site [active]
85569000266	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
85569000267	intersubunit interface [polypeptide binding]; other site
85569000268	active site
85569000269	Zn2+ binding site [ion binding]; other site
85569000270	L-arabinose isomerase; Provisional; Region: PRK02929
85569000271	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
85569000272	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
85569000273	trimer interface [polypeptide binding]; other site
85569000274	putative substrate binding site [chemical binding]; other site
85569000275	putative metal binding site [ion binding]; other site
85569000276	ribulokinase; Provisional; Region: PRK04123
85569000277	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
85569000278	N- and C-terminal domain interface [polypeptide binding]; other site
85569000279	active site
85569000280	MgATP binding site [chemical binding]; other site
85569000281	catalytic site [active]
85569000282	metal binding site [ion binding]; metal-binding site
85569000283	carbohydrate binding site [chemical binding]; other site
85569000284	homodimer interface [polypeptide binding]; other site
85569000285	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
85569000286	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
85569000287	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569000288	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569000289	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
85569000290	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
85569000291	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569000292	Walker A/P-loop; other site
85569000293	ATP binding site [chemical binding]; other site
85569000294	Q-loop/lid; other site
85569000295	ABC transporter signature motif; other site
85569000296	Walker B; other site
85569000297	D-loop; other site
85569000298	H-loop/switch region; other site
85569000299	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
85569000300	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569000301	dimer interface [polypeptide binding]; other site
85569000302	conserved gate region; other site
85569000303	putative PBP binding loops; other site
85569000304	ABC-ATPase subunit interface; other site
85569000305	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569000306	dimer interface [polypeptide binding]; other site
85569000307	conserved gate region; other site
85569000308	putative PBP binding loops; other site
85569000309	ABC-ATPase subunit interface; other site
85569000310	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
85569000311	transcriptional regulator SgrR; Provisional; Region: PRK13626
85569000312	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
85569000313	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
85569000314	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
85569000315	substrate binding site [chemical binding]; other site
85569000316	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
85569000317	substrate binding site [chemical binding]; other site
85569000318	ligand binding site [chemical binding]; other site
85569000319	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
85569000320	2-isopropylmalate synthase; Validated; Region: PRK00915
85569000321	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
85569000322	active site
85569000323	catalytic residues [active]
85569000324	metal binding site [ion binding]; metal-binding site
85569000325	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
85569000326	leu operon leader peptide; Provisional; Region: PRK14744
85569000327	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
85569000328	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569000329	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
85569000330	putative substrate binding pocket [chemical binding]; other site
85569000331	putative dimerization interface [polypeptide binding]; other site
85569000332	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
85569000333	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
85569000334	dimer interface [polypeptide binding]; other site
85569000335	PYR/PP interface [polypeptide binding]; other site
85569000336	TPP binding site [chemical binding]; other site
85569000337	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
85569000338	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
85569000339	TPP-binding site [chemical binding]; other site
85569000340	dimer interface [polypeptide binding]; other site
85569000341	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
85569000342	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
85569000343	putative valine binding site [chemical binding]; other site
85569000344	dimer interface [polypeptide binding]; other site
85569000345	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
85569000346	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
85569000347	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
85569000348	DNA binding site [nucleotide binding]
85569000349	domain linker motif; other site
85569000350	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
85569000351	dimerization interface [polypeptide binding]; other site
85569000352	ligand binding site [chemical binding]; other site
85569000353	mraZ protein; Region: TIGR00242
85569000354	MraZ protein; Region: MraZ; pfam02381
85569000355	MraZ protein; Region: MraZ; pfam02381
85569000356	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
85569000357	cell division protein FtsL; Provisional; Region: PRK10772
85569000358	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
85569000359	Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717
85569000360	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
85569000361	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
85569000362	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
85569000363	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
85569000364	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
85569000365	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
85569000366	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
85569000367	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
85569000368	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
85569000369	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
85569000370	Mg++ binding site [ion binding]; other site
85569000371	putative catalytic motif [active]
85569000372	putative substrate binding site [chemical binding]; other site
85569000373	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
85569000374	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
85569000375	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
85569000376	cell division protein FtsW; Provisional; Region: PRK10774
85569000377	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
85569000378	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
85569000379	active site
85569000380	homodimer interface [polypeptide binding]; other site
85569000381	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
85569000382	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
85569000383	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
85569000384	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
85569000385	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
85569000386	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
85569000387	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
85569000388	cell division protein FtsQ; Provisional; Region: PRK10775
85569000389	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
85569000390	Cell division protein FtsQ; Region: FtsQ; pfam03799
85569000391	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
85569000392	Cell division protein FtsA; Region: FtsA; pfam14450
85569000393	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
85569000394	Cell division protein FtsA; Region: FtsA; pfam14450
85569000395	cell division protein FtsZ; Validated; Region: PRK09330
85569000396	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
85569000397	nucleotide binding site [chemical binding]; other site
85569000398	SulA interaction site; other site
85569000399	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
85569000400	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
85569000401	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
85569000402	SecA regulator SecM; Provisional; Region: PRK02943
85569000403	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
85569000404	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
85569000405	SecA Wing and Scaffold domain; Region: SecA_SW; pfam07516
85569000406	SEC-C motif; Region: SEC-C; pfam02810
85569000407	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
85569000408	active site
85569000409	8-oxo-dGMP binding site [chemical binding]; other site
85569000410	nudix motif; other site
85569000411	metal binding site [ion binding]; metal-binding site
85569000412	DNA gyrase inhibitor; Reviewed; Region: PRK00418
85569000413	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
85569000414	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
85569000415	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
85569000416	CoA-binding site [chemical binding]; other site
85569000417	ATP-binding [chemical binding]; other site
85569000418	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
85569000419	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
85569000420	active site
85569000421	type IV pilin biogenesis protein; Provisional; Region: PRK10573
85569000422	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
85569000423	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
85569000424	hypothetical protein; Provisional; Region: PRK10436
85569000425	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
85569000426	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
85569000427	Walker A motif; other site
85569000428	ATP binding site [chemical binding]; other site
85569000429	Walker B motif; other site
85569000430	putative major pilin subunit; Provisional; Region: PRK10574
85569000431	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
85569000432	Pilin (bacterial filament); Region: Pilin; pfam00114
85569000433	nicotinate-nucleotide pyrophosphorylase; Region: nadC; TIGR00078
85569000434	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
85569000435	dimerization interface [polypeptide binding]; other site
85569000436	active site
85569000437	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
85569000438	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
85569000439	amidase catalytic site [active]
85569000440	Zn binding residues [ion binding]; other site
85569000441	substrate binding site [chemical binding]; other site
85569000442	regulatory protein AmpE; Provisional; Region: PRK10987
85569000443	Glycosyl hydrolase family 43; Region: GH43_1; cd08980
85569000444	active site
85569000445	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
85569000446	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569000447	putative substrate translocation pore; other site
85569000448	aromatic amino acid transporter; Provisional; Region: PRK10238
85569000449	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
85569000450	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
85569000451	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569000452	DNA-binding site [nucleotide binding]; DNA binding site
85569000453	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
85569000454	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
85569000455	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
85569000456	dimer interface [polypeptide binding]; other site
85569000457	TPP-binding site [chemical binding]; other site
85569000458	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
85569000459	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
85569000460	E3 interaction surface; other site
85569000461	lipoyl attachment site [posttranslational modification]; other site
85569000462	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
85569000463	E3 interaction surface; other site
85569000464	lipoyl attachment site [posttranslational modification]; other site
85569000465	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
85569000466	E3 interaction surface; other site
85569000467	lipoyl attachment site [posttranslational modification]; other site
85569000468	e3 binding domain; Region: E3_binding; pfam02817
85569000469	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
85569000470	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
85569000471	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569000472	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
85569000473	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
85569000474	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
85569000475	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
85569000476	Aconitate B N-terminal domain; Region: Aconitase_B_N; pfam11791
85569000477	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
85569000478	substrate binding site [chemical binding]; other site
85569000479	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
85569000480	substrate binding site [chemical binding]; other site
85569000481	ligand binding site [chemical binding]; other site
85569000482	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3112
85569000483	2-keto-3-deoxygluconate permease; Provisional; Region: PRK12460
85569000484	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
85569000485	4-hydroxythreonine-4-phosphate dehydrogenase 2; Provisional; Region: pdxA; PRK03371
85569000486	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
85569000487	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
85569000488	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
85569000489	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569000490	S-adenosylmethionine binding site [chemical binding]; other site
85569000491	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
85569000492	multicopper oxidase; Provisional; Region: PRK10965
85569000493	Cupredoxin superfamily; Region: Cupredoxin; cl19115
85569000494	The second Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_2_CueO_FtsP; cd13867
85569000495	Domain 1 interface [polypeptide binding]; other site
85569000496	Domain 3 interface [polypeptide binding]; other site
85569000497	The third Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_3_CueO_FtsP; cd13890
85569000498	Domain 2 interface [polypeptide binding]; other site
85569000499	Domain 1 interface [polypeptide binding]; other site
85569000500	Type 1 (T1) Cu binding site [ion binding]; other site
85569000501	trinuclear Cu binding site [ion binding]; other site
85569000502	Glucose dehydrogenase [Carbohydrate transport and metabolism]; Region: Gcd; COG4993
85569000503	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
85569000504	Trp docking motif [polypeptide binding]; other site
85569000505	putative active site [active]
85569000506	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
85569000507	active site
85569000508	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
85569000509	active site clefts [active]
85569000510	zinc binding site [ion binding]; other site
85569000511	dimer interface [polypeptide binding]; other site
85569000512	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
85569000513	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569000514	Walker A/P-loop; other site
85569000515	ATP binding site [chemical binding]; other site
85569000516	Q-loop/lid; other site
85569000517	ABC transporter signature motif; other site
85569000518	Walker B; other site
85569000519	D-loop; other site
85569000520	H-loop/switch region; other site
85569000521	inner membrane transport permease; Provisional; Region: PRK15066
85569000522	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
85569000523	putative fimbrial protein StiH; Provisional; Region: PRK15297
85569000524	fimbrial outer membrane usher protein StiC; Provisional; Region: PRK15298
85569000525	PapC N-terminal domain; Region: PapC_N; pfam13954
85569000526	Outer membrane usher protein; Region: Usher; pfam00577
85569000527	PapC C-terminal domain; Region: PapC_C; pfam13953
85569000528	fimbrial protein StiA; Provisional; Region: PRK15300
85569000529	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
85569000530	active pocket/dimerization site; other site
85569000531	active site
85569000532	phosphorylation site [posttranslational modification]
85569000533	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
85569000534	putative active site [active]
85569000535	putative metal binding site [ion binding]; other site
85569000536	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
85569000537	tetramerization interface [polypeptide binding]; other site
85569000538	active site
85569000539	Pantoate-beta-alanine ligase; Region: PanC; cd00560
85569000540	active site
85569000541	ATP-binding site [chemical binding]; other site
85569000542	pantoate-binding site; other site
85569000543	HXXH motif; other site
85569000544	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
85569000545	oligomerization interface [polypeptide binding]; other site
85569000546	active site
85569000547	metal binding site [ion binding]; metal-binding site
85569000548	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
85569000549	catalytic center binding site [active]
85569000550	ATP binding site [chemical binding]; other site
85569000551	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
85569000552	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
85569000553	active site
85569000554	NTP binding site [chemical binding]; other site
85569000555	metal binding triad [ion binding]; metal-binding site
85569000556	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
85569000557	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
85569000558	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
85569000559	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
85569000560	active site
85569000561	nucleotide binding site [chemical binding]; other site
85569000562	HIGH motif; other site
85569000563	KMSKS motif; other site
85569000564	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
85569000565	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
85569000566	2'-5' RNA ligase; Provisional; Region: PRK15124
85569000567	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
85569000568	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
85569000569	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
85569000570	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
85569000571	ATP binding site [chemical binding]; other site
85569000572	putative Mg++ binding site [ion binding]; other site
85569000573	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
85569000574	nucleotide binding region [chemical binding]; other site
85569000575	ATP-binding site [chemical binding]; other site
85569000576	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
85569000577	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
85569000578	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
85569000579	Transmembrane domain of transglycosylase PBP1 at N-terminal; Region: PBP1_TM; pfam14812
85569000580	Bifunctional transglycosylase second domain; Region: UB2H; pfam14814
85569000581	Transglycosylase; Region: Transgly; pfam00912
85569000582	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
85569000583	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
85569000584	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
85569000585	N-terminal plug; other site
85569000586	ligand-binding site [chemical binding]; other site
85569000587	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
85569000588	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
85569000589	Walker A/P-loop; other site
85569000590	ATP binding site [chemical binding]; other site
85569000591	Q-loop/lid; other site
85569000592	ABC transporter signature motif; other site
85569000593	Walker B; other site
85569000594	D-loop; other site
85569000595	H-loop/switch region; other site
85569000596	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
85569000597	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
85569000598	siderophore binding site; other site
85569000599	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
85569000600	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
85569000601	ABC-ATPase subunit  interface; other site
85569000602	dimer interface [polypeptide binding]; other site
85569000603	putative PBP binding regions; other site
85569000604	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
85569000605	ABC-ATPase subunit  interface; other site
85569000606	dimer interface [polypeptide binding]; other site
85569000607	putative PBP binding regions; other site
85569000608	putative fimbrial subunit StfA; Provisional; Region: PRK15283
85569000609	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
85569000610	PapC N-terminal domain; Region: PapC_N; pfam13954
85569000611	Outer membrane usher protein; Region: Usher; pfam00577
85569000612	PapC C-terminal domain; Region: PapC_C; pfam13953
85569000613	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
85569000614	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
85569000615	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
85569000616	putative minor fimbrial subunit StfE; Provisional; Region: PRK15286
85569000617	putative minor fimbrial subunit StfF; Provisional; Region: PRK15287
85569000618	putative minor fimbrial subunit StfG; Provisional; Region: PRK15288
85569000619	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
85569000620	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
85569000621	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
85569000622	inhibitor-cofactor binding pocket; inhibition site
85569000623	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569000624	catalytic residue [active]
85569000625	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
85569000626	Cl- selectivity filter; other site
85569000627	Cl- binding residues [ion binding]; other site
85569000628	pore gating glutamate residue; other site
85569000629	dimer interface [polypeptide binding]; other site
85569000630	H+/Cl- coupling transport residue; other site
85569000631	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
85569000632	hypothetical protein; Provisional; Region: PRK10578
85569000633	UPF0126 domain; Region: UPF0126; pfam03458
85569000634	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
85569000635	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
85569000636	cobalamin binding residues [chemical binding]; other site
85569000637	putative BtuC binding residues; other site
85569000638	dimer interface [polypeptide binding]; other site
85569000639	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
85569000640	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
85569000641	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
85569000642	Zn2+ binding site [ion binding]; other site
85569000643	Mg2+ binding site [ion binding]; other site
85569000644	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
85569000645	serine endoprotease; Provisional; Region: PRK10942
85569000646	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
85569000647	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
85569000648	protein binding site [polypeptide binding]; other site
85569000649	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
85569000650	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
85569000651	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
85569000652	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
85569000653	hypothetical protein; Provisional; Region: PRK13677
85569000654	shikimate transporter; Provisional; Region: PRK09952
85569000655	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569000656	putative substrate translocation pore; other site
85569000657	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
85569000658	Tetrahydrodipicolinate N-succinyltransferase N-terminal; Region: THDPS_N_2; pfam14805
85569000659	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
85569000660	trimer interface [polypeptide binding]; other site
85569000661	active site
85569000662	substrate binding site [chemical binding]; other site
85569000663	CoA binding site [chemical binding]; other site
85569000664	PII uridylyl-transferase; Provisional; Region: PRK05007
85569000665	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
85569000666	metal binding triad; other site
85569000667	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
85569000668	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
85569000669	Zn2+ binding site [ion binding]; other site
85569000670	Mg2+ binding site [ion binding]; other site
85569000671	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
85569000672	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
85569000673	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
85569000674	active site
85569000675	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
85569000676	rRNA interaction site [nucleotide binding]; other site
85569000677	S8 interaction site; other site
85569000678	putative laminin-1 binding site; other site
85569000679	elongation factor Ts; Provisional; Region: tsf; PRK09377
85569000680	UBA/TS-N domain; Region: UBA; pfam00627
85569000681	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
85569000682	putative nucleotide binding site [chemical binding]; other site
85569000683	uridine monophosphate binding site [chemical binding]; other site
85569000684	homohexameric interface [polypeptide binding]; other site
85569000685	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
85569000686	hinge region; other site
85569000687	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
85569000688	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
85569000689	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
85569000690	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
85569000691	Cis (Z)-Isoprenyl Diphosphate Synthases; Region: Cis_IPPS; cd00475
85569000692	active site
85569000693	dimer interface [polypeptide binding]; other site
85569000694	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
85569000695	zinc metallopeptidase RseP; Provisional; Region: PRK10779
85569000696	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
85569000697	active site
85569000698	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
85569000699	protein binding site [polypeptide binding]; other site
85569000700	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
85569000701	protein binding site [polypeptide binding]; other site
85569000702	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
85569000703	putative substrate binding region [chemical binding]; other site
85569000704	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
85569000705	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
85569000706	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
85569000707	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
85569000708	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
85569000709	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
85569000710	Surface antigen; Region: Bac_surface_Ag; pfam01103
85569000711	periplasmic chaperone; Provisional; Region: PRK10780
85569000712	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
85569000713	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
85569000714	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
85569000715	trimer interface [polypeptide binding]; other site
85569000716	active site
85569000717	UDP-GlcNAc binding site [chemical binding]; other site
85569000718	lipid binding site [chemical binding]; lipid-binding site
85569000719	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
85569000720	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
85569000721	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
85569000722	active site
85569000723	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
85569000724	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
85569000725	Bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
85569000726	RNA/DNA hybrid binding site [nucleotide binding]; other site
85569000727	active site
85569000728	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
85569000729	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
85569000730	putative active site [active]
85569000731	putative PHP Thumb interface [polypeptide binding]; other site
85569000732	Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733
85569000733	Helix-hairpin-helix motif; Region: HHH_6; pfam14579
85569000734	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
85569000735	generic binding surface II; other site
85569000736	generic binding surface I; other site
85569000737	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
85569000738	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
85569000739	Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some...; Region: chitinase_glyco_hydro_19; cd00325
85569000740	putative sugar binding site [chemical binding]; other site
85569000741	catalytic residues [active]
85569000742	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
85569000743	lysine decarboxylase LdcC; Provisional; Region: PRK15399
85569000744	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
85569000745	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
85569000746	homodimer interface [polypeptide binding]; other site
85569000747	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569000748	catalytic residue [active]
85569000749	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
85569000750	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
85569000751	putative metal binding site [ion binding]; other site
85569000752	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
85569000753	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
85569000754	TilS substrate binding domain; Region: TilS; pfam09179
85569000755	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
85569000756	Rho-binding antiterminator; Provisional; Region: PRK11625
85569000757	hypothetical protein; Provisional; Region: PRK04964
85569000758	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
85569000759	hypothetical protein; Provisional; Region: PRK09256
85569000760	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
85569000761	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
85569000762	NlpE N-terminal domain; Region: NlpE; cl19736
85569000763	prolyl-tRNA synthetase; Provisional; Region: PRK09194
85569000764	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
85569000765	dimer interface [polypeptide binding]; other site
85569000766	motif 1; other site
85569000767	active site
85569000768	motif 2; other site
85569000769	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
85569000770	putative deacylase active site [active]
85569000771	motif 3; other site
85569000772	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
85569000773	anticodon binding site; other site
85569000774	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
85569000775	homodimer interaction site [polypeptide binding]; other site
85569000776	cofactor binding site; other site
85569000777	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
85569000778	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
85569000779	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569000780	dimer interface [polypeptide binding]; other site
85569000781	conserved gate region; other site
85569000782	putative PBP binding loops; other site
85569000783	ABC-ATPase subunit interface; other site
85569000784	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
85569000785	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
85569000786	Walker A/P-loop; other site
85569000787	ATP binding site [chemical binding]; other site
85569000788	Q-loop/lid; other site
85569000789	ABC transporter signature motif; other site
85569000790	Walker B; other site
85569000791	D-loop; other site
85569000792	H-loop/switch region; other site
85569000793	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
85569000794	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
85569000795	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569000796	active site
85569000797	motif I; other site
85569000798	motif II; other site
85569000799	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
85569000800	active site
85569000801	catalytic tetrad [active]
85569000802	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569000803	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569000804	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
85569000805	putative effector binding pocket; other site
85569000806	dimerization interface [polypeptide binding]; other site
85569000807	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
85569000808	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569000809	putative substrate translocation pore; other site
85569000810	hypothetical protein; Provisional; Region: PRK05421
85569000811	putative catalytic site [active]
85569000812	putative metal binding site [ion binding]; other site
85569000813	putative phosphate binding site [ion binding]; other site
85569000814	putative catalytic site [active]
85569000815	putative phosphate binding site [ion binding]; other site
85569000816	putative metal binding site [ion binding]; other site
85569000817	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569000818	S-adenosylmethionine binding site [chemical binding]; other site
85569000819	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
85569000820	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
85569000821	N-acetyl-D-glucosamine binding site [chemical binding]; other site
85569000822	catalytic residue [active]
85569000823	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
85569000824	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
85569000825	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
85569000826	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569000827	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
85569000828	RNA/DNA hybrid binding site [nucleotide binding]; other site
85569000829	active site
85569000830	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
85569000831	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
85569000832	active site
85569000833	catalytic site [active]
85569000834	substrate binding site [chemical binding]; other site
85569000835	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
85569000836	ImpA-related N-terminal; Region: ImpA-rel_N; cl19907
85569000837	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
85569000838	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3518
85569000839	Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only]; Region: ImpE; COG4455
85569000840	ImpE protein; Region: ImpE; pfam07024
85569000841	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
85569000842	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569000843	Walker A motif; other site
85569000844	ATP binding site [chemical binding]; other site
85569000845	Walker B motif; other site
85569000846	arginine finger; other site
85569000847	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569000848	Walker A motif; other site
85569000849	ATP binding site [chemical binding]; other site
85569000850	Walker B motif; other site
85569000851	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
85569000852	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
85569000853	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
85569000854	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
85569000855	Domain of unknown function (DUF4285); Region: DUF4285; pfam14113
85569000856	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
85569000857	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
85569000858	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
85569000859	hypothetical protein; Provisional; Region: PRK08126
85569000860	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
85569000861	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
85569000862	ligand binding site [chemical binding]; other site
85569000863	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
85569000864	ImcF-related N-terminal domain; Region: ImcF-related_N; pfam14331
85569000865	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
85569000866	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
85569000867	Uncharacterized protein conserved in bacteria (DUF2094); Region: DUF2094; cl01611
85569000868	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4893
85569000869	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501
85569000870	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
85569000871	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
85569000872	Uncharacterized conserved protein [Function unknown]; Region: COG5435
85569000873	PAAR motif; Region: PAAR_motif; pfam05488
85569000874	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
85569000875	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
85569000876	Immunity protein 14; Region: Imm14; pfam15428
85569000877	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; cl07446
85569000878	Toxin SymE, type I toxin-antitoxin system; Region: SymE_toxin; pfam08845
85569000879	Transposase; Region: HTH_Tnp_1; cl17663
85569000880	Saf-pilin pilus formation protein SafA; Provisional; Region: PRK15221
85569000881	pili assembly chaperone protein SafB; Provisional; Region: PRK15224
85569000882	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
85569000883	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
85569000884	pilin outer membrane usher protein SafC; Provisional; Region: PRK15223
85569000885	PapC N-terminal domain; Region: PapC_N; pfam13954
85569000886	Outer membrane usher protein; Region: Usher; pfam00577
85569000887	PapC C-terminal domain; Region: PapC_C; pfam13953
85569000888	putative pilin structural protein SafD; Provisional; Region: PRK15222
85569000889	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
85569000890	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
85569000891	putative active site [active]
85569000892	putative metal binding site [ion binding]; other site
85569000893	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569000894	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569000895	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
85569000896	dimerization interface [polypeptide binding]; other site
85569000897	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
85569000898	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
85569000899	dimer interface [polypeptide binding]; other site
85569000900	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
85569000901	putative active site [active]
85569000902	catalytic triad [active]
85569000903	dimer interface [polypeptide binding]; other site
85569000904	multimer interface [polypeptide binding]; other site
85569000905	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
85569000906	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
85569000907	active site
85569000908	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
85569000909	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
85569000910	putative active site [active]
85569000911	Glutamine amidotransferases class-II; Region: GATase_2; pfam00310
85569000912	putative dimer interface [polypeptide binding]; other site
85569000913	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
85569000914	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
85569000915	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
85569000916	active site
85569000917	DNA polymerase IV; Validated; Region: PRK02406
85569000918	DNA binding site [nucleotide binding]
85569000919	Uncharacterized conserved protein [Function unknown]; Region: RtcB; cl17455
85569000920	tRNA-splicing ligase RtcB; Region: RtcB; pfam01139
85569000921	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
85569000922	putative peptide chain release factor H; Region: release_prfH; TIGR03072
85569000923	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
85569000924	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
85569000925	metal binding site [ion binding]; metal-binding site
85569000926	dimer interface [polypeptide binding]; other site
85569000927	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
85569000928	active site
85569000929	Putative lysophospholipase; Region: Hydrolase_4; cl19140
85569000930	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
85569000931	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
85569000932	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
85569000933	trimer interface [polypeptide binding]; other site
85569000934	eyelet of channel; other site
85569000935	gamma-glutamyl kinase; Provisional; Region: PRK05429
85569000936	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
85569000937	nucleotide binding site [chemical binding]; other site
85569000938	homotetrameric interface [polypeptide binding]; other site
85569000939	putative phosphate binding site [ion binding]; other site
85569000940	putative allosteric binding site; other site
85569000941	PUA domain; Region: PUA; pfam01472
85569000942	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
85569000943	putative catalytic cysteine [active]
85569000944	integrase; Provisional; Region: int; PHA02601
85569000945	P22-like integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial and phage integrases, including those similar to phage P22-like integrases, DLP12 and APSE-1; Region: INT_P22_C; cd01192
85569000946	Int/Topo IB signature motif; other site
85569000947	Helix-turn-helix domain; Region: HTH_17; pfam12728
85569000948	ASCH domain; Region: ASCH; pfam04266
85569000949	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
85569000950	Protein of unknown function (DUF551); Region: DUF551; pfam04448
85569000951	Protein of unknown function (DUF2856); Region: DUF2856; pfam11043
85569000952	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
85569000953	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
85569000954	Rad52/22 family double-strand break repair protein; Region: Rad52_Rad22; cl01936
85569000955	Suppressor of G2 allele of skp1 and related proteins [General function prediction only]; Region: SGT1; COG5091
85569000956	Lambda Phage CIII; Region: Lambda_CIII; pfam02061
85569000957	hypothetical protein; Region: PHA01516
85569000958	Antirestriction protein Ral; Region: Ral; pfam11058
85569000959	Superinfection exclusion protein B; Region: SieB; pfam14163
85569000960	P63C domain; Region: P63C; pfam10546
85569000961	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569000962	non-specific DNA binding site [nucleotide binding]; other site
85569000963	Predicted transcriptional regulator [Transcription]; Region: COG2932
85569000964	salt bridge; other site
85569000965	sequence-specific DNA binding site [nucleotide binding]; other site
85569000966	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
85569000967	Catalytic site [active]
85569000968	Bacteriophage CII protein; Region: Phage_CII; pfam05269
85569000969	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
85569000970	replicative DNA helicase; Region: DnaB; TIGR00665
85569000971	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
85569000972	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
85569000973	Walker A motif; other site
85569000974	ATP binding site [chemical binding]; other site
85569000975	Walker B motif; other site
85569000976	DNA binding loops [nucleotide binding]
85569000977	NinB protein; Region: NinB; pfam05772
85569000978	hypothetical protein; Region: PHA01519
85569000979	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
85569000980	Antitermination protein; Region: Antiterm; pfam03589
85569000981	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cl19048
85569000982	Antitermination protein; Region: Antiterm; pfam03589
85569000983	Bacteriophage Rz lysis protein; Region: Phage_lysis; pfam03245
85569000984	Terminase-like family; Region: Terminase_6; pfam03237
85569000985	Bacteriophage terminase large (ATPase) subunit and inactivated derivatives [General function prediction only]; Region: COG5565
85569000986	Bacteriophage, scaffolding protein; Region: Phage-scaffold; pfam09306
85569000987	coat protein; Region: PHA01511
85569000988	P22 tail accessory factor; Region: P22_Tail-4; pfam11650
85569000989	Phage stabilisation protein; Region: Phage_stabilize; pfam11134
85569000990	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
85569000991	head assembly protein; Region: PHA00771
85569000992	Head binding; Region: Head_binding; pfam09008
85569000993	Salmonella phage P22 tail-spike; Region: PhageP22-tail; pfam09251
85569000994	O-antigen conversion protein C; Region: PHA01514
85569000995	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
85569000996	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
85569000997	Ligand binding site; other site
85569000998	Putative Catalytic site; other site
85569000999	DXD motif; other site
85569001000	Predicted membrane protein [Function unknown]; Region: COG2246
85569001001	HTH-like domain; Region: HTH_21; pfam13276
85569001002	Integrase core domain; Region: rve; pfam00665
85569001003	Integrase core domain; Region: rve_3; pfam13683
85569001004	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
85569001005	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
85569001006	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569001007	putative substrate translocation pore; other site
85569001008	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
85569001009	substrate binding site [chemical binding]; other site
85569001010	ligand binding site [chemical binding]; other site
85569001011	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
85569001012	substrate binding site [chemical binding]; other site
85569001013	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
85569001014	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
85569001015	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
85569001016	Putative lysophospholipase; Region: Hydrolase_4; cl19140
85569001017	YjzC-like protein; Region: YjzC; pfam14168
85569001018	fimbrial assembly chaperone StbE; Provisional; Region: PRK15246
85569001019	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
85569001020	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
85569001021	putative fimbrial usher protein StbD; Provisional; Region: PRK15247
85569001022	fimbrial outer membrane usher protein StbC; Provisional; Region: PRK15248
85569001023	PapC N-terminal domain; Region: PapC_N; pfam13954
85569001024	Outer membrane usher protein; Region: Usher; pfam00577
85569001025	PapC C-terminal domain; Region: PapC_C; pfam13953
85569001026	fimbrial chaperone protein StbB; Provisional; Region: PRK15249
85569001027	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
85569001028	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
85569001029	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
85569001030	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
85569001031	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
85569001032	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
85569001033	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
85569001034	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
85569001035	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
85569001036	DNA binding site [nucleotide binding]
85569001037	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
85569001038	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
85569001039	DNA binding residues [nucleotide binding]
85569001040	dimerization interface [polypeptide binding]; other site
85569001041	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
85569001042	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
85569001043	Outer membrane efflux protein; Region: OEP; pfam02321
85569001044	Outer membrane efflux protein; Region: OEP; pfam02321
85569001045	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
85569001046	MMPL family; Region: MMPL; cl14618
85569001047	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
85569001048	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
85569001049	HlyD family secretion protein; Region: HlyD_3; pfam13437
85569001050	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
85569001051	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
85569001052	metal-binding site [ion binding]
85569001053	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
85569001054	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569001055	motif II; other site
85569001056	Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044
85569001057	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
85569001058	DNA binding residues [nucleotide binding]
85569001059	dimer interface [polypeptide binding]; other site
85569001060	copper binding site [ion binding]; other site
85569001061	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
85569001062	metal-binding site [ion binding]
85569001063	putative sialic acid transporter; Region: 2A0112; TIGR00891
85569001064	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569001065	putative substrate translocation pore; other site
85569001066	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
85569001067	DNA methylase; Region: N6_N4_Mtase; cl17433
85569001068	DNA methylase; Region: N6_N4_Mtase; pfam01555
85569001069	type III restriction-modification system StyLTI enzyme res; Provisional; Region: PRK15483
85569001070	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
85569001071	ATP binding site [chemical binding]; other site
85569001072	VRR-NUC domain; Region: VRR_NUC; pfam08774
85569001073	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
85569001074	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
85569001075	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
85569001076	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569001077	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
85569001078	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
85569001079	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
85569001080	N-terminal plug; other site
85569001081	ligand-binding site [chemical binding]; other site
85569001082	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
85569001083	hypothetical protein; Provisional; Region: PRK09929
85569001084	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
85569001085	Propionate catabolism activator; Region: PrpR_N; pfam06506
85569001086	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569001087	Walker A motif; other site
85569001088	ATP binding site [chemical binding]; other site
85569001089	Walker B motif; other site
85569001090	arginine finger; other site
85569001091	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
85569001092	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
85569001093	tetramer interface [polypeptide binding]; other site
85569001094	active site
85569001095	Mg2+/Mn2+ binding site [ion binding]; other site
85569001096	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
85569001097	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
85569001098	dimer interface [polypeptide binding]; other site
85569001099	active site
85569001100	citrylCoA binding site [chemical binding]; other site
85569001101	oxalacetate/citrate binding site [chemical binding]; other site
85569001102	coenzyme A binding site [chemical binding]; other site
85569001103	catalytic triad [active]
85569001104	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
85569001105	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
85569001106	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
85569001107	acyl-activating enzyme (AAE) consensus motif; other site
85569001108	AMP binding site [chemical binding]; other site
85569001109	active site
85569001110	CoA binding site [chemical binding]; other site
85569001111	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
85569001112	dimer interface [polypeptide binding]; other site
85569001113	active site
85569001114	Schiff base residues; other site
85569001115	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
85569001116	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
85569001117	Autotransporter beta-domain; Region: Autotransporter; pfam03797
85569001118	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
85569001119	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
85569001120	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
85569001121	ligand binding site [chemical binding]; other site
85569001122	flexible hinge region; other site
85569001123	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
85569001124	microcin B17 transporter; Reviewed; Region: PRK11098
85569001125	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
85569001126	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
85569001127	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
85569001128	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
85569001129	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
85569001130	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
85569001131	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3921
85569001132	Extensin-like protein C-terminus; Region: Extensin-like_C; pfam06904
85569001133	drug efflux system protein MdtG; Provisional; Region: PRK09874
85569001134	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569001135	putative substrate translocation pore; other site
85569001136	anti-RssB factor; Provisional; Region: PRK10244
85569001137	hypothetical protein; Provisional; Region: PRK11505
85569001138	psiF repeat; Region: PsiF_repeat; pfam07769
85569001139	psiF repeat; Region: PsiF_repeat; pfam07769
85569001140	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
85569001141	MASE2 domain; Region: MASE2; pfam05230
85569001142	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
85569001143	metal binding site [ion binding]; metal-binding site
85569001144	active site
85569001145	I-site; other site
85569001146	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
85569001147	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
85569001148	Pyrroline-5-carboxylate reductase dimerization; Region: P5CR_dimer; pfam14748
85569001149	hypothetical protein; Validated; Region: PRK00124
85569001150	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
85569001151	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
85569001152	ADP binding site [chemical binding]; other site
85569001153	magnesium binding site [ion binding]; other site
85569001154	putative shikimate binding site; other site
85569001155	hypothetical protein; Provisional; Region: PRK10380
85569001156	hypothetical protein; Provisional; Region: PRK10481
85569001157	hypothetical protein; Provisional; Region: PRK10579
85569001158	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
85569001159	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
85569001160	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
85569001161	nucleotide binding site [chemical binding]; other site
85569001162	MFS transport protein AraJ; Provisional; Region: PRK10091
85569001163	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569001164	putative substrate translocation pore; other site
85569001165	exonuclease subunit SbcC; Provisional; Region: PRK10246
85569001166	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569001167	Walker A/P-loop; other site
85569001168	ATP binding site [chemical binding]; other site
85569001169	Q-loop/lid; other site
85569001170	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569001171	ABC transporter signature motif; other site
85569001172	Walker B; other site
85569001173	D-loop; other site
85569001174	H-loop/switch region; other site
85569001175	exonuclease subunit SbcD; Provisional; Region: PRK10966
85569001176	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
85569001177	active site
85569001178	metal binding site [ion binding]; metal-binding site
85569001179	DNA binding site [nucleotide binding]
85569001180	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
85569001181	transcriptional regulator PhoB; Provisional; Region: PRK10161
85569001182	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569001183	active site
85569001184	phosphorylation site [posttranslational modification]
85569001185	intermolecular recognition site; other site
85569001186	dimerization interface [polypeptide binding]; other site
85569001187	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
85569001188	DNA binding site [nucleotide binding]
85569001189	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
85569001190	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
85569001191	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
85569001192	putative active site [active]
85569001193	heme pocket [chemical binding]; other site
85569001194	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569001195	dimer interface [polypeptide binding]; other site
85569001196	phosphorylation site [posttranslational modification]
85569001197	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569001198	ATP binding site [chemical binding]; other site
85569001199	Mg2+ binding site [ion binding]; other site
85569001200	G-X-G motif; other site
85569001201	Transposase IS200 like; Region: Y1_Tnp; pfam01797
85569001202	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
85569001203	putative proline-specific permease; Provisional; Region: proY; PRK10580
85569001204	Spore germination protein; Region: Spore_permease; cl17796
85569001205	maltodextrin glucosidase; Provisional; Region: PRK10785
85569001206	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
85569001207	homodimer interface [polypeptide binding]; other site
85569001208	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
85569001209	active site
85569001210	homodimer interface [polypeptide binding]; other site
85569001211	catalytic site [active]
85569001212	peroxidase; Provisional; Region: PRK15000
85569001213	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
85569001214	dimer interface [polypeptide binding]; other site
85569001215	decamer (pentamer of dimers) interface [polypeptide binding]; other site
85569001216	catalytic triad [active]
85569001217	peroxidatic and resolving cysteines [active]
85569001218	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
85569001219	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
85569001220	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
85569001221	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
85569001222	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
85569001223	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
85569001224	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
85569001225	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
85569001226	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
85569001227	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
85569001228	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
85569001229	Protein export membrane protein; Region: SecD_SecF; pfam02355
85569001230	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
85569001231	Predicted transcriptional regulator [Transcription]; Region: COG2378
85569001232	HTH domain; Region: HTH_11; pfam08279
85569001233	WYL domain; Region: WYL; pfam13280
85569001234	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
85569001235	active site
85569001236	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
85569001237	hypothetical protein; Provisional; Region: PRK11530
85569001238	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
85569001239	ATP cone domain; Region: ATP-cone; pfam03477
85569001240	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
85569001241	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
85569001242	catalytic motif [active]
85569001243	Zn binding site [ion binding]; other site
85569001244	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
85569001245	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
85569001246	homopentamer interface [polypeptide binding]; other site
85569001247	active site
85569001248	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
85569001249	thiamine monophosphate kinase; Provisional; Region: PRK05731
85569001250	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
85569001251	ATP binding site [chemical binding]; other site
85569001252	dimerization interface [polypeptide binding]; other site
85569001253	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
85569001254	tetramer interfaces [polypeptide binding]; other site
85569001255	binuclear metal-binding site [ion binding]; other site
85569001256	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
85569001257	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
85569001258	active site
85569001259	catalytic tetrad [active]
85569001260	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
85569001261	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
85569001262	TPP-binding site; other site
85569001263	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
85569001264	PYR/PP interface [polypeptide binding]; other site
85569001265	dimer interface [polypeptide binding]; other site
85569001266	TPP binding site [chemical binding]; other site
85569001267	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
85569001268	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
85569001269	substrate binding pocket [chemical binding]; other site
85569001270	chain length determination region; other site
85569001271	active site lid residues [active]
85569001272	substrate-Mg2+ binding site; other site
85569001273	catalytic residues [active]
85569001274	aspartate-rich region 1; other site
85569001275	aspartate-rich region 2; other site
85569001276	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
85569001277	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
85569001278	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
85569001279	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
85569001280	Ligand Binding Site [chemical binding]; other site
85569001281	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
85569001282	active site residue [active]
85569001283	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
85569001284	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569001285	dimer interface [polypeptide binding]; other site
85569001286	conserved gate region; other site
85569001287	putative PBP binding loops; other site
85569001288	ABC-ATPase subunit interface; other site
85569001289	2-aminoethylphosphonate transport system permease PhnU; Provisional; Region: PRK15050
85569001290	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569001291	dimer interface [polypeptide binding]; other site
85569001292	conserved gate region; other site
85569001293	putative PBP binding loops; other site
85569001294	ABC-ATPase subunit interface; other site
85569001295	2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Region: PhnT; TIGR03258
85569001296	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569001297	Walker A/P-loop; other site
85569001298	ATP binding site [chemical binding]; other site
85569001299	Q-loop/lid; other site
85569001300	ABC transporter signature motif; other site
85569001301	Walker B; other site
85569001302	D-loop; other site
85569001303	H-loop/switch region; other site
85569001304	TOBE domain; Region: TOBE_2; pfam08402
85569001305	2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional; Region: PRK15046
85569001306	transcriptional regulator protein; Region: phnR; TIGR03337
85569001307	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569001308	DNA-binding site [nucleotide binding]; DNA binding site
85569001309	UTRA domain; Region: UTRA; pfam07702
85569001310	2-aminoethylphosphonate--pyruvate transaminase; Region: transamin_PhnW; TIGR02326
85569001311	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
85569001312	catalytic residue [active]
85569001313	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
85569001314	phosphonoacetaldehyde hydrolase; Region: phosphonatase; TIGR01422
85569001315	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569001316	motif II; other site
85569001317	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
85569001318	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
85569001319	conserved cys residue [active]
85569001320	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
85569001321	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
85569001322	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
85569001323	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
85569001324	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569001325	Major Facilitator Superfamily; Region: MFS_1; pfam07690
85569001326	putative substrate translocation pore; other site
85569001327	Exodeoxyribonuclease V, gamma subunit; Region: Exonuc_V_gamma; cl19914
85569001328	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
85569001329	Sel1 repeat; Region: Sel1; pfam08238
85569001330	Sel1-like repeats; Region: SEL1; smart00671
85569001331	Protoheme IX farnesyltransferase; Region: PT_UbiA_Cox10; cd13957
85569001332	putative active site [active]
85569001333	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
85569001334	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
85569001335	Subunit III/IV interface [polypeptide binding]; other site
85569001336	Subunit I/III interface [polypeptide binding]; other site
85569001337	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
85569001338	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
85569001339	D-pathway; other site
85569001340	Putative ubiquinol binding site [chemical binding]; other site
85569001341	Low-spin heme (heme b) binding site [chemical binding]; other site
85569001342	Putative water exit pathway; other site
85569001343	Binuclear center (heme o3/CuB) [ion binding]; other site
85569001344	K-pathway; other site
85569001345	Putative proton exit pathway; other site
85569001346	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
85569001347	The cupredoxin domain of Ubiquinol oxidase subunit II; Region: CuRO_UO_II; cd04212
85569001348	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
85569001349	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569001350	Major Facilitator Superfamily; Region: MFS_1; pfam07690
85569001351	putative substrate translocation pore; other site
85569001352	hypothetical protein; Provisional; Region: PRK11627
85569001353	transcriptional regulator BolA; Provisional; Region: PRK11628
85569001354	trigger factor; Provisional; Region: tig; PRK01490
85569001355	Bacterial trigger factor protein (TF); Region: Trigger_N; pfam05697
85569001356	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
85569001357	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
85569001358	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
85569001359	oligomer interface [polypeptide binding]; other site
85569001360	active site residues [active]
85569001361	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
85569001362	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
85569001363	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569001364	Walker A motif; other site
85569001365	ATP binding site [chemical binding]; other site
85569001366	Walker B motif; other site
85569001367	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
85569001368	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
85569001369	ATP-dependent protease La (LON) domain; Region: LON; pfam02190
85569001370	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569001371	Walker A motif; other site
85569001372	ATP binding site [chemical binding]; other site
85569001373	Walker B motif; other site
85569001374	arginine finger; other site
85569001375	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
85569001376	periplasmic folding chaperone; Provisional; Region: PRK10788
85569001377	SurA N-terminal domain; Region: SurA_N_3; cl07813
85569001378	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
85569001379	DNA uptake protein and related DNA-binding proteins [DNA replication, recombination, and repair]; Region: ComEA; COG1555
85569001380	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
85569001381	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
85569001382	active site
85569001383	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
85569001384	Ligand Binding Site [chemical binding]; other site
85569001385	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
85569001386	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
85569001387	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
85569001388	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
85569001389	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
85569001390	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569001391	active site
85569001392	motif I; other site
85569001393	motif II; other site
85569001394	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
85569001395	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
85569001396	catalytic residue [active]
85569001397	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
85569001398	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
85569001399	putative DNA binding site [nucleotide binding]; other site
85569001400	putative Zn2+ binding site [ion binding]; other site
85569001401	AsnC family; Region: AsnC_trans_reg; pfam01037
85569001402	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
85569001403	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
85569001404	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569001405	Walker A/P-loop; other site
85569001406	ATP binding site [chemical binding]; other site
85569001407	Q-loop/lid; other site
85569001408	ABC transporter signature motif; other site
85569001409	Walker B; other site
85569001410	D-loop; other site
85569001411	H-loop/switch region; other site
85569001412	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
85569001413	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
85569001414	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569001415	Walker A/P-loop; other site
85569001416	ATP binding site [chemical binding]; other site
85569001417	Q-loop/lid; other site
85569001418	ABC transporter signature motif; other site
85569001419	Walker B; other site
85569001420	D-loop; other site
85569001421	H-loop/switch region; other site
85569001422	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
85569001423	ammonium transporter; Provisional; Region: PRK10666
85569001424	acyl-CoA thioesterase II; Provisional; Region: PRK10526
85569001425	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
85569001426	active site
85569001427	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
85569001428	catalytic triad [active]
85569001429	dimer interface [polypeptide binding]; other site
85569001430	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
85569001431	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
85569001432	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
85569001433	DNA binding site [nucleotide binding]
85569001434	active site
85569001435	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
85569001436	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
85569001437	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
85569001438	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
85569001439	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
85569001440	Inner membrane protein YlaC; Region: YlaC; pfam10777
85569001441	maltose O-acetyltransferase; Provisional; Region: PRK10092
85569001442	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
85569001443	active site
85569001444	substrate binding site [chemical binding]; other site
85569001445	trimer interface [polypeptide binding]; other site
85569001446	CoA binding site [chemical binding]; other site
85569001447	gene expression modulator; Provisional; Region: PRK10945
85569001448	Hha toxicity attenuator; Provisional; Region: PRK10667
85569001449	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
85569001450	MMPL family; Region: MMPL; cl14618
85569001451	MMPL family; Region: MMPL; cl14618
85569001452	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
85569001453	Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169
85569001454	HlyD family secretion protein; Region: HlyD_3; pfam13437
85569001455	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
85569001456	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
85569001457	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
85569001458	hypothetical protein; Provisional; Region: PRK11281
85569001459	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
85569001460	Mechanosensitive ion channel; Region: MS_channel; pfam00924
85569001461	hypothetical protein; Provisional; Region: PRK11038
85569001462	Uncharacterized conserved protein [Function unknown]; Region: COG5464
85569001463	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
85569001464	primosomal replication protein N''; Provisional; Region: PRK10093
85569001465	hypothetical protein; Provisional; Region: PRK10527
85569001466	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
85569001467	active site
85569001468	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
85569001469	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569001470	Walker A motif; other site
85569001471	ATP binding site [chemical binding]; other site
85569001472	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl18944
85569001473	Walker B motif; other site
85569001474	arginine finger; other site
85569001475	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
85569001476	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
85569001477	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
85569001478	hypothetical protein; Validated; Region: PRK00153
85569001479	recombination protein RecR; Reviewed; Region: recR; PRK00076
85569001480	RecR protein; Region: RecR; pfam02132
85569001481	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
85569001482	putative active site [active]
85569001483	putative metal-binding site [ion binding]; other site
85569001484	tetramer interface [polypeptide binding]; other site
85569001485	heat shock protein 90; Provisional; Region: PRK05218
85569001486	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569001487	ATP binding site [chemical binding]; other site
85569001488	Mg2+ binding site [ion binding]; other site
85569001489	G-X-G motif; other site
85569001490	Hsp90 protein; Region: HSP90; pfam00183
85569001491	adenylate kinase; Reviewed; Region: adk; PRK00279
85569001492	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
85569001493	AMP-binding site [chemical binding]; other site
85569001494	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
85569001495	ferrochelatase; Reviewed; Region: hemH; PRK00035
85569001496	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
85569001497	C-terminal domain interface [polypeptide binding]; other site
85569001498	active site
85569001499	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
85569001500	active site
85569001501	N-terminal domain interface [polypeptide binding]; other site
85569001502	acetyl esterase; Provisional; Region: PRK10162
85569001503	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
85569001504	inosine/guanosine kinase; Provisional; Region: PRK15074
85569001505	substrate binding site [chemical binding]; other site
85569001506	ATP binding site [chemical binding]; other site
85569001507	putative cation:proton antiport protein; Provisional; Region: PRK10669
85569001508	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
85569001509	TrkA-N domain; Region: TrkA_N; pfam02254
85569001510	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569001511	Major Facilitator Superfamily; Region: MFS_1; pfam07690
85569001512	putative substrate translocation pore; other site
85569001513	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
85569001514	putative deacylase active site [active]
85569001515	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
85569001516	copper exporting ATPase; Provisional; Region: copA; PRK10671
85569001517	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
85569001518	metal-binding site [ion binding]
85569001519	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
85569001520	metal-binding site [ion binding]
85569001521	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
85569001522	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569001523	motif II; other site
85569001524	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
85569001525	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
85569001526	DNA binding residues [nucleotide binding]
85569001527	dimer interface [polypeptide binding]; other site
85569001528	copper binding site [ion binding]; other site
85569001529	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
85569001530	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
85569001531	Paraslipin or slipin-2 (SLP-2, a subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_paraslipin; cd08829
85569001532	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
85569001533	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
85569001534	Walker A/P-loop; other site
85569001535	ATP binding site [chemical binding]; other site
85569001536	Q-loop/lid; other site
85569001537	ABC transporter signature motif; other site
85569001538	Walker B; other site
85569001539	D-loop; other site
85569001540	H-loop/switch region; other site
85569001541	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390
85569001542	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
85569001543	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
85569001544	Tetratricopeptide repeat; Region: TPR_20; pfam14561
85569001545	short chain dehydrogenase; Validated; Region: PRK06182
85569001546	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
85569001547	NADP binding site [chemical binding]; other site
85569001548	active site
85569001549	steroid binding site; other site
85569001550	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
85569001551	active site
85569001552	catalytic triad [active]
85569001553	oxyanion hole [active]
85569001554	switch loop; other site
85569001555	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
85569001556	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
85569001557	Walker A/P-loop; other site
85569001558	ATP binding site [chemical binding]; other site
85569001559	Q-loop/lid; other site
85569001560	ABC transporter signature motif; other site
85569001561	Walker B; other site
85569001562	D-loop; other site
85569001563	H-loop/switch region; other site
85569001564	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
85569001565	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
85569001566	FtsX-like permease family; Region: FtsX; pfam02687
85569001567	FtsX-like permease family; Region: FtsX; pfam02687
85569001568	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
85569001569	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
85569001570	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
85569001571	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
85569001572	Walker A/P-loop; other site
85569001573	ATP binding site [chemical binding]; other site
85569001574	Q-loop/lid; other site
85569001575	ABC transporter signature motif; other site
85569001576	Walker B; other site
85569001577	D-loop; other site
85569001578	H-loop/switch region; other site
85569001579	NIL domain; Region: NIL; pfam09383
85569001580	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569001581	dimer interface [polypeptide binding]; other site
85569001582	conserved gate region; other site
85569001583	putative PBP binding loops; other site
85569001584	ABC-ATPase subunit interface; other site
85569001585	Predicted ATPase [General function prediction only]; Region: COG2603
85569001586	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
85569001587	active site residue [active]
85569001588	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
85569001589	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569001590	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
85569001591	dimerization interface [polypeptide binding]; other site
85569001592	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
85569001593	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
85569001594	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
85569001595	Bacterial transcriptional regulator; Region: IclR; pfam01614
85569001596	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
85569001597	PYR/PP interface [polypeptide binding]; other site
85569001598	dimer interface [polypeptide binding]; other site
85569001599	TPP binding site [chemical binding]; other site
85569001600	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
85569001601	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
85569001602	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
85569001603	putative substrate binding site [chemical binding]; other site
85569001604	nucleotide binding site [chemical binding]; other site
85569001605	nucleotide binding site [chemical binding]; other site
85569001606	homodimer interface [polypeptide binding]; other site
85569001607	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) [Nucleotide transport and metabolism]; Region: PurK; COG0026
85569001608	ATP-grasp domain; Region: ATP-grasp; pfam02222
85569001609	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
85569001610	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
85569001611	putative active site [active]
85569001612	putative metal binding site [ion binding]; other site
85569001613	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
85569001614	substrate binding site [chemical binding]; other site
85569001615	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
85569001616	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
85569001617	active site
85569001618	HIGH motif; other site
85569001619	KMSKS motif; other site
85569001620	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
85569001621	tRNA binding surface [nucleotide binding]; other site
85569001622	anticodon binding site; other site
85569001623	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4727
85569001624	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
85569001625	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
85569001626	RNA binding surface [nucleotide binding]; other site
85569001627	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
85569001628	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
85569001629	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
85569001630	homodimer interface [polypeptide binding]; other site
85569001631	NADP binding site [chemical binding]; other site
85569001632	substrate binding site [chemical binding]; other site
85569001633	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
85569001634	fimbrial protein FimI; Provisional; Region: PRK15200
85569001635	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
85569001636	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
85569001637	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
85569001638	outer membrane usher protein FimD; Provisional; Region: PRK15198
85569001639	PapC N-terminal domain; Region: PapC_N; pfam13954
85569001640	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
85569001641	PapC C-terminal domain; Region: PapC_C; pfam13953
85569001642	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
85569001643	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
85569001644	transcriptional regulator FimZ; Provisional; Region: PRK09935
85569001645	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569001646	active site
85569001647	phosphorylation site [posttranslational modification]
85569001648	intermolecular recognition site; other site
85569001649	dimerization interface [polypeptide binding]; other site
85569001650	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569001651	DNA binding residues [nucleotide binding]
85569001652	dimerization interface [polypeptide binding]; other site
85569001653	putative diguanylate cyclase; Provisional; Region: PRK13561
85569001654	fimbriae regulatory protein FimW; Provisional; Region: PRK15201
85569001655	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569001656	DNA binding residues [nucleotide binding]
85569001657	dimerization interface [polypeptide binding]; other site
85569001658	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
85569001659	Transposase; Region: HTH_Tnp_1; cl17663
85569001660	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
85569001661	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
85569001662	Ligand binding site; other site
85569001663	Putative Catalytic site; other site
85569001664	DXD motif; other site
85569001665	Predicted membrane protein [Function unknown]; Region: COG2246
85569001666	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569001667	ATP binding site [chemical binding]; other site
85569001668	Mg2+ binding site [ion binding]; other site
85569001669	G-X-G motif; other site
85569001670	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
85569001671	Cupin; Region: Cupin_6; pfam12852
85569001672	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
85569001673	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569001674	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569001675	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
85569001676	Squalene epoxidase; Region: SE; cl17314
85569001677	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
85569001678	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
85569001679	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
85569001680	Predicted membrane protein [Function unknown]; Region: COG3059
85569001681	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
85569001682	phenylalanine transporter; Provisional; Region: PRK10249
85569001683	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
85569001684	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
85569001685	Mechanosensitive ion channel; Region: MS_channel; pfam00924
85569001686	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
85569001687	Triacylglycerol lipase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: Triacylglycerol_lipase_like; cd01847
85569001688	active site
85569001689	catalytic triad [active]
85569001690	oxyanion hole [active]
85569001691	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
85569001692	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
85569001693	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569001694	Walker A motif; other site
85569001695	ATP binding site [chemical binding]; other site
85569001696	Walker B motif; other site
85569001697	arginine finger; other site
85569001698	Transcriptional antiterminator [Transcription]; Region: COG3933
85569001699	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
85569001700	active pocket/dimerization site; other site
85569001701	active site
85569001702	phosphorylation site [posttranslational modification]
85569001703	PRD domain; Region: PRD; pfam00874
85569001704	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
85569001705	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
85569001706	putative active site [active]
85569001707	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
85569001708	dimer interface [polypeptide binding]; other site
85569001709	active site
85569001710	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
85569001711	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
85569001712	dimer interface [polypeptide binding]; other site
85569001713	active site
85569001714	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
85569001715	dimer interface [polypeptide binding]; other site
85569001716	active site
85569001717	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
85569001718	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
85569001719	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
85569001720	active site
85569001721	phosphorylation site [posttranslational modification]
85569001722	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
85569001723	active pocket/dimerization site; other site
85569001724	active site
85569001725	phosphorylation site [posttranslational modification]
85569001726	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
85569001727	dimer interface [polypeptide binding]; other site
85569001728	FMN binding site [chemical binding]; other site
85569001729	hypothetical protein; Provisional; Region: PRK10250
85569001730	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
85569001731	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
85569001732	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
85569001733	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569001734	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569001735	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
85569001736	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
85569001737	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
85569001738	outer membrane receptor FepA; Provisional; Region: PRK13524
85569001739	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
85569001740	N-terminal plug; other site
85569001741	ligand-binding site [chemical binding]; other site
85569001742	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
85569001743	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
85569001744	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819; cl19187
85569001745	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
85569001746	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
85569001747	Condensation domain; Region: Condensation; cl19241
85569001748	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
85569001749	acyl-activating enzyme (AAE) consensus motif; other site
85569001750	AMP binding site [chemical binding]; other site
85569001751	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
85569001752	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
85569001753	LPS O-antigen length regulator; Provisional; Region: PRK10381
85569001754	Chain length determinant protein; Region: Wzz; pfam02706
85569001755	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
85569001756	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
85569001757	Walker A/P-loop; other site
85569001758	ATP binding site [chemical binding]; other site
85569001759	Q-loop/lid; other site
85569001760	ABC transporter signature motif; other site
85569001761	Walker B; other site
85569001762	D-loop; other site
85569001763	H-loop/switch region; other site
85569001764	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
85569001765	ABC-ATPase subunit  interface; other site
85569001766	dimer interface [polypeptide binding]; other site
85569001767	putative PBP binding regions; other site
85569001768	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
85569001769	ABC-ATPase subunit  interface; other site
85569001770	dimer interface [polypeptide binding]; other site
85569001771	putative PBP binding regions; other site
85569001772	enterobactin exporter EntS; Provisional; Region: PRK10489
85569001773	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569001774	putative substrate translocation pore; other site
85569001775	ABC-type Fe2+-enterobactin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG4592
85569001776	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
85569001777	siderophore binding site; other site
85569001778	isochorismate synthase EntC; Provisional; Region: PRK15016
85569001779	chorismate binding enzyme; Region: Chorismate_bind; cl10555
85569001780	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
85569001781	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
85569001782	acyl-activating enzyme (AAE) consensus motif; other site
85569001783	active site
85569001784	AMP binding site [chemical binding]; other site
85569001785	substrate binding site [chemical binding]; other site
85569001786	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
85569001787	hydrophobic substrate binding pocket; other site
85569001788	active site
85569001789	conserved cis-peptide bond; other site
85569001790	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
85569001791	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
85569001792	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
85569001793	putative NAD(P) binding site [chemical binding]; other site
85569001794	active site
85569001795	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
85569001796	CoenzymeA binding site [chemical binding]; other site
85569001797	subunit interaction site [polypeptide binding]; other site
85569001798	PHB binding site; other site
85569001799	carbon starvation protein A; Provisional; Region: PRK15015
85569001800	Carbon starvation protein CstA; Region: CstA; pfam02554
85569001801	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
85569001802	Uncharacterized small protein [Function unknown]; Region: COG2879
85569001803	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
85569001804	putative active site [active]
85569001805	metal binding site [ion binding]; metal-binding site
85569001806	methionine aminotransferase; Validated; Region: PRK09082
85569001807	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
85569001808	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569001809	homodimer interface [polypeptide binding]; other site
85569001810	catalytic residue [active]
85569001811	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
85569001812	ParB-like nuclease domain; Region: ParBc; pfam02195
85569001813	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
85569001814	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
85569001815	Active Sites [active]
85569001816	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
85569001817	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
85569001818	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569001819	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
85569001820	dimerization interface [polypeptide binding]; other site
85569001821	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
85569001822	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
85569001823	dimerization domain [polypeptide binding]; other site
85569001824	dimer interface [polypeptide binding]; other site
85569001825	catalytic residues [active]
85569001826	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
85569001827	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
85569001828	dimer interface [polypeptide binding]; other site
85569001829	decamer (pentamer of dimers) interface [polypeptide binding]; other site
85569001830	catalytic triad [active]
85569001831	peroxidatic and resolving cysteines [active]
85569001832	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
85569001833	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
85569001834	catalytic residue [active]
85569001835	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
85569001836	catalytic residues [active]
85569001837	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569001838	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
85569001839	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
85569001840	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
85569001841	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
85569001842	putative [4Fe-4S] binding site [ion binding]; other site
85569001843	putative molybdopterin cofactor binding site [chemical binding]; other site
85569001844	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
85569001845	molybdopterin cofactor binding site; other site
85569001846	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
85569001847	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
85569001848	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
85569001849	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
85569001850	Ligand Binding Site [chemical binding]; other site
85569001851	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
85569001852	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
85569001853	NAD binding site [chemical binding]; other site
85569001854	catalytic Zn binding site [ion binding]; other site
85569001855	structural Zn binding site [ion binding]; other site
85569001856	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
85569001857	Rnk N-terminus; Region: Rnk_N; pfam14760
85569001858	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
85569001859	ribonuclease I; Provisional; Region: PRK10095
85569001860	CAS motifs; other site
85569001861	active site
85569001862	anion transporter; Region: dass; TIGR00785
85569001863	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
85569001864	transmembrane helices; other site
85569001865	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
85569001866	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
85569001867	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
85569001868	Coenzyme A transferase; Region: CoA_trans; cl17247
85569001869	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
85569001870	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
85569001871	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
85569001872	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
85569001873	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
85569001874	putative active site [active]
85569001875	(T/H)XGH motif; other site
85569001876	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
85569001877	Sensory domain of two-component sensor kinase; Region: Cache_3; pfam14827
85569001878	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
85569001879	putative active site [active]
85569001880	heme pocket [chemical binding]; other site
85569001881	Sensor_kinase_SpoOB-type, alpha-helical domain; Region: SPOB_a; pfam14689
85569001882	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569001883	ATP binding site [chemical binding]; other site
85569001884	Mg2+ binding site [ion binding]; other site
85569001885	G-X-G motif; other site
85569001886	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
85569001887	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569001888	active site
85569001889	phosphorylation site [posttranslational modification]
85569001890	intermolecular recognition site; other site
85569001891	dimerization interface [polypeptide binding]; other site
85569001892	Transcriptional regulator; Region: CitT; pfam12431
85569001893	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
85569001894	C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; COG3069
85569001895	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
85569001896	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
85569001897	DNA-binding site [nucleotide binding]; DNA binding site
85569001898	RNA-binding motif; other site
85569001899	chromosome condensation membrane protein; Provisional; Region: PRK14196
85569001900	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
85569001901	putative active site [active]
85569001902	catalytic triad [active]
85569001903	putative dimer interface [polypeptide binding]; other site
85569001904	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
85569001905	lipoyl synthase; Provisional; Region: PRK05481
85569001906	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569001907	FeS/SAM binding site; other site
85569001908	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
85569001909	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569001910	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
85569001911	dimerization interface [polypeptide binding]; other site
85569001912	lipoate-protein ligase B; Provisional; Region: PRK14342
85569001913	hypothetical protein; Provisional; Region: PRK04998
85569001914	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
85569001915	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
85569001916	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
85569001917	rare lipoprotein A; Provisional; Region: PRK10672
85569001918	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
85569001919	Sporulation related domain; Region: SPOR; pfam05036
85569001920	cell wall shape-determining protein; Provisional; Region: PRK10794
85569001921	penicillin-binding protein 2; Provisional; Region: PRK10795
85569001922	Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717
85569001923	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
85569001924	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
85569001925	ribosome-associated protein; Provisional; Region: PRK11538
85569001926	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
85569001927	catalytic core [active]
85569001928	threonine-phosphate decarboxylase; Provisional; Region: PRK08056
85569001929	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
85569001930	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569001931	homodimer interface [polypeptide binding]; other site
85569001932	catalytic residue [active]
85569001933	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
85569001934	active site
85569001935	(T/H)XGH motif; other site
85569001936	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
85569001937	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
85569001938	Processivity clamp loader gamma complex DNA pol III C-term; Region: DNA_pol3_delt_C; pfam14840
85569001939	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
85569001940	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
85569001941	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
85569001942	HIGH motif; other site
85569001943	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
85569001944	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
85569001945	active site
85569001946	KMSKS motif; other site
85569001947	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
85569001948	tRNA binding surface [nucleotide binding]; other site
85569001949	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
85569001950	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
85569001951	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
85569001952	Propionate catabolism activator; Region: PrpR_N; pfam06506
85569001953	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
85569001954	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569001955	Walker A motif; other site
85569001956	ATP binding site [chemical binding]; other site
85569001957	Walker B motif; other site
85569001958	arginine finger; other site
85569001959	hypothetical protein; Provisional; Region: PRK11032
85569001960	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
85569001961	Sel1-like repeats; Region: SEL1; smart00671
85569001962	Sel1-like repeats; Region: SEL1; smart00671
85569001963	Sel1-like repeats; Region: SEL1; smart00671
85569001964	Sel1-like repeats; Region: SEL1; smart00671
85569001965	Sel1-like repeats; Region: SEL1; smart00671
85569001966	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
85569001967	Sel1 repeat; Region: Sel1; pfam08238
85569001968	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
85569001969	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
85569001970	HSP70 interaction site [polypeptide binding]; other site
85569001971	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
85569001972	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
85569001973	HSP70 interaction site [polypeptide binding]; other site
85569001974	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
85569001975	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
85569001976	nucleotide binding site [chemical binding]; other site
85569001977	putative NEF/HSP70 interaction site [polypeptide binding]; other site
85569001978	SBD interface [polypeptide binding]; other site
85569001979	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
85569001980	active site
85569001981	tetramer interface [polypeptide binding]; other site
85569001982	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
85569001983	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
85569001984	Walker A/P-loop; other site
85569001985	ATP binding site [chemical binding]; other site
85569001986	Q-loop/lid; other site
85569001987	ABC transporter signature motif; other site
85569001988	Walker B; other site
85569001989	D-loop; other site
85569001990	H-loop/switch region; other site
85569001991	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765
85569001992	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569001993	dimer interface [polypeptide binding]; other site
85569001994	conserved gate region; other site
85569001995	putative PBP binding loops; other site
85569001996	ABC-ATPase subunit interface; other site
85569001997	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765
85569001998	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569001999	dimer interface [polypeptide binding]; other site
85569002000	conserved gate region; other site
85569002001	putative PBP binding loops; other site
85569002002	ABC-ATPase subunit interface; other site
85569002003	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
85569002004	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
85569002005	substrate binding pocket [chemical binding]; other site
85569002006	membrane-bound complex binding site; other site
85569002007	hinge residues; other site
85569002008	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
85569002009	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
85569002010	putative active site [active]
85569002011	catalytic triad [active]
85569002012	putative dimer interface [polypeptide binding]; other site
85569002013	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
85569002014	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
85569002015	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
85569002016	Transporter associated domain; Region: CorC_HlyC; smart01091
85569002017	metal-binding heat shock protein; Provisional; Region: PRK00016
85569002018	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
85569002019	PhoH-like protein; Region: PhoH; pfam02562
85569002020	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
85569002021	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
85569002022	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569002023	FeS/SAM binding site; other site
85569002024	TRAM domain; Region: TRAM; pfam01938
85569002025	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
85569002026	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
85569002027	asparagine synthetase B; Provisional; Region: asnB; PRK09431
85569002028	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
85569002029	active site
85569002030	dimer interface [polypeptide binding]; other site
85569002031	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
85569002032	Ligand Binding Site [chemical binding]; other site
85569002033	Molecular Tunnel; other site
85569002034	UMP phosphatase; Provisional; Region: PRK10444
85569002035	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569002036	active site
85569002037	motif I; other site
85569002038	motif II; other site
85569002039	MarR family; Region: MarR_2; cl17246
85569002040	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
85569002041	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
85569002042	nucleotide binding site [chemical binding]; other site
85569002043	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
85569002044	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
85569002045	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
85569002046	active site
85569002047	dimer interface [polypeptide binding]; other site
85569002048	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
85569002049	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
85569002050	active site
85569002051	trimer interface [polypeptide binding]; other site
85569002052	allosteric site; other site
85569002053	active site lid [active]
85569002054	hexamer (dimer of trimers) interface [polypeptide binding]; other site
85569002055	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
85569002056	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
85569002057	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
85569002058	active site turn [active]
85569002059	phosphorylation site [posttranslational modification]
85569002060	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
85569002061	HPr interaction site; other site
85569002062	glycerol kinase (GK) interaction site [polypeptide binding]; other site
85569002063	active site
85569002064	phosphorylation site [posttranslational modification]
85569002065	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
85569002066	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
85569002067	active site
85569002068	HIGH motif; other site
85569002069	KMSKS motif; other site
85569002070	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
85569002071	outer membrane porin, OprD family; Region: OprD; pfam03573
85569002072	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
85569002073	YbfN-like lipoprotein; Region: YbfN; pfam13982
85569002074	citrate-proton symporter; Provisional; Region: PRK15075
85569002075	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569002076	putative substrate translocation pore; other site
85569002077	tricarballylate utilization protein B; Provisional; Region: PRK15033
85569002078	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
85569002079	tricarballylate dehydrogenase; Validated; Region: PRK08274
85569002080	precorrin 3B synthase CobZ; Region: CobZ_N-term; TIGR02485
85569002081	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569002082	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569002083	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
85569002084	dimerization interface [polypeptide binding]; other site
85569002085	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
85569002086	metal binding site 2 [ion binding]; metal-binding site
85569002087	putative DNA binding helix; other site
85569002088	metal binding site 1 [ion binding]; metal-binding site
85569002089	dimer interface [polypeptide binding]; other site
85569002090	structural Zn2+ binding site [ion binding]; other site
85569002091	flavodoxin FldA; Validated; Region: PRK09267
85569002092	LexA regulated protein; Provisional; Region: PRK11675
85569002093	acyl-CoA esterase; Provisional; Region: PRK10673
85569002094	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
85569002095	replication initiation regulator SeqA; Provisional; Region: PRK11187
85569002096	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
85569002097	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
85569002098	active site
85569002099	substrate binding site [chemical binding]; other site
85569002100	metal binding site [ion binding]; metal-binding site
85569002101	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
85569002102	putrescine transporter; Provisional; Region: potE; PRK10655
85569002103	ornithine decarboxylase; Provisional; Region: PRK13578
85569002104	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
85569002105	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
85569002106	homodimer interface [polypeptide binding]; other site
85569002107	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569002108	catalytic residue [active]
85569002109	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
85569002110	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
85569002111	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569002112	active site
85569002113	phosphorylation site [posttranslational modification]
85569002114	intermolecular recognition site; other site
85569002115	dimerization interface [polypeptide binding]; other site
85569002116	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
85569002117	DNA binding site [nucleotide binding]
85569002118	sensor protein KdpD; Provisional; Region: PRK10490
85569002119	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
85569002120	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
85569002121	Ligand Binding Site [chemical binding]; other site
85569002122	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
85569002123	GAF domain; Region: GAF_3; pfam13492
85569002124	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569002125	dimer interface [polypeptide binding]; other site
85569002126	phosphorylation site [posttranslational modification]
85569002127	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569002128	ATP binding site [chemical binding]; other site
85569002129	Mg2+ binding site [ion binding]; other site
85569002130	G-X-G motif; other site
85569002131	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
85569002132	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
85569002133	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
85569002134	Soluble P-type ATPase [General function prediction only]; Region: COG4087
85569002135	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
85569002136	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
85569002137	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
85569002138	DNA photolyase; Region: DNA_photolyase; pfam00875
85569002139	FAD binding domain of DNA photolyase; Region: FAD_binding_7; pfam03441
85569002140	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
85569002141	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569002142	putative substrate translocation pore; other site
85569002143	metal-binding protein; Provisional; Region: PRK10799
85569002144	Allophanate hydrolase subunit 1; Region: AHS1; cl19310
85569002145	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
85569002146	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
85569002147	putative active site [active]
85569002148	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
85569002149	active site
85569002150	DNA binding site [nucleotide binding]
85569002151	Int/Topo IB signature motif; other site
85569002152	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
85569002153	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
85569002154	UDP-galactopyranose mutase; Region: GLF; pfam03275
85569002155	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
85569002156	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
85569002157	active site
85569002158	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
85569002159	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
85569002160	putative ADP-binding pocket [chemical binding]; other site
85569002161	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
85569002162	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
85569002163	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
85569002164	Walker A/P-loop; other site
85569002165	ATP binding site [chemical binding]; other site
85569002166	Q-loop/lid; other site
85569002167	ABC transporter signature motif; other site
85569002168	Walker B; other site
85569002169	D-loop; other site
85569002170	H-loop/switch region; other site
85569002171	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
85569002172	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
85569002173	active site
85569002174	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
85569002175	active site
85569002176	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG5610
85569002177	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
85569002178	endonuclease VIII; Provisional; Region: PRK10445
85569002179	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
85569002180	DNA binding site [nucleotide binding]
85569002181	catalytic residue [active]
85569002182	putative catalytic residues [active]
85569002183	H2TH interface [polypeptide binding]; other site
85569002184	intercalation triad [nucleotide binding]; other site
85569002185	substrate specificity determining residue; other site
85569002186	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
85569002187	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
85569002188	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
85569002189	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
85569002190	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
85569002191	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
85569002192	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
85569002193	dimer interface [polypeptide binding]; other site
85569002194	active site
85569002195	citrylCoA binding site [chemical binding]; other site
85569002196	NADH binding [chemical binding]; other site
85569002197	cationic pore residues; other site
85569002198	oxalacetate/citrate binding site [chemical binding]; other site
85569002199	coenzyme A binding site [chemical binding]; other site
85569002200	catalytic triad [active]
85569002201	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
85569002202	Iron-sulfur protein interface; other site
85569002203	proximal quinone binding site [chemical binding]; other site
85569002204	SdhD (CybS) interface [polypeptide binding]; other site
85569002205	proximal heme binding site [chemical binding]; other site
85569002206	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
85569002207	SdhC subunit interface [polypeptide binding]; other site
85569002208	proximal heme binding site [chemical binding]; other site
85569002209	cardiolipin binding site; other site
85569002210	Iron-sulfur protein interface; other site
85569002211	proximal quinone binding site [chemical binding]; other site
85569002212	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
85569002213	L-aspartate oxidase; Provisional; Region: PRK06175
85569002214	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
85569002215	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
85569002216	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
85569002217	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
85569002218	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
85569002219	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
85569002220	TPP-binding site [chemical binding]; other site
85569002221	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
85569002222	dimer interface [polypeptide binding]; other site
85569002223	PYR/PP interface [polypeptide binding]; other site
85569002224	TPP binding site [chemical binding]; other site
85569002225	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
85569002226	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
85569002227	E3 interaction surface; other site
85569002228	lipoyl attachment site [posttranslational modification]; other site
85569002229	e3 binding domain; Region: E3_binding; pfam02817
85569002230	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
85569002231	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
85569002232	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
85569002233	CoA-ligase; Region: Ligase_CoA; pfam00549
85569002234	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
85569002235	CoA binding domain; Region: CoA_binding; pfam02629
85569002236	CoA-ligase; Region: Ligase_CoA; pfam00549
85569002237	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
85569002238	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
85569002239	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
85569002240	Predicted outer membrane lipoprotein [Function unknown]; Region: COG4890
85569002241	hypothetical protein; Provisional; Region: PRK10588
85569002242	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
85569002243	active site
85569002244	colicin uptake protein TolQ; Provisional; Region: PRK10801
85569002245	colicin uptake protein TolR; Provisional; Region: PRK11024
85569002246	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
85569002247	TolA C-terminal; Region: TolA; pfam06519
85569002248	translocation protein TolB; Provisional; Region: tolB; PRK03629
85569002249	TolB amino-terminal domain; Region: TolB_N; pfam04052
85569002250	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
85569002251	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
85569002252	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
85569002253	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
85569002254	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
85569002255	ligand binding site [chemical binding]; other site
85569002256	tol-pal system protein YbgF; Provisional; Region: PRK10803
85569002257	YfhG lipoprotein; Region: Lipoprotein_20; cl08141
85569002258	Tetratricopeptide repeat; Region: TPR_6; pfam13174
85569002259	Tetratricopeptide repeat; Region: TPR_6; pfam13174
85569002260	quinolinate synthetase; Provisional; Region: PRK09375
85569002261	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
85569002262	zinc transporter ZitB; Provisional; Region: PRK03557
85569002263	YbgS-like protein; Region: YbgS; pfam13985
85569002264	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
85569002265	Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain [Energy production and conversion]; Region: FumA; COG1838
85569002266	fumarate hydratase; Provisional; Region: PRK06246
85569002267	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569002268	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569002269	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
85569002270	dimerization interface [polypeptide binding]; other site
85569002271	cell density-dependent motility repressor; Provisional; Region: PRK10082
85569002272	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569002273	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
85569002274	dimerization interface [polypeptide binding]; other site
85569002275	oxaloacetate decarboxylase; Provisional; Region: PRK14040
85569002276	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
85569002277	active site
85569002278	catalytic residues [active]
85569002279	metal binding site [ion binding]; metal-binding site
85569002280	homodimer binding site [polypeptide binding]; other site
85569002281	Conserved carboxylase domain; Region: PYC_OADA; pfam02436
85569002282	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
85569002283	carboxyltransferase (CT) interaction site; other site
85569002284	biotinylation site [posttranslational modification]; other site
85569002285	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15476
85569002286	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
85569002287	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
85569002288	ABC-ATPase subunit  interface; other site
85569002289	dimer interface [polypeptide binding]; other site
85569002290	putative PBP binding regions; other site
85569002291	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
85569002292	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
85569002293	Walker A/P-loop; other site
85569002294	ATP binding site [chemical binding]; other site
85569002295	Q-loop/lid; other site
85569002296	ABC transporter signature motif; other site
85569002297	Walker B; other site
85569002298	D-loop; other site
85569002299	H-loop/switch region; other site
85569002300	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
85569002301	catalytic core [active]
85569002302	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
85569002303	active site
85569002304	catalytic residues [active]
85569002305	galactokinase; Provisional; Region: PRK05101
85569002306	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
85569002307	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
85569002308	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
85569002309	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
85569002310	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
85569002311	dimer interface [polypeptide binding]; other site
85569002312	active site
85569002313	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
85569002314	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
85569002315	NAD binding site [chemical binding]; other site
85569002316	homodimer interface [polypeptide binding]; other site
85569002317	active site
85569002318	substrate binding site [chemical binding]; other site
85569002319	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4714
85569002320	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
85569002321	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569002322	Walker A/P-loop; other site
85569002323	ATP binding site [chemical binding]; other site
85569002324	Q-loop/lid; other site
85569002325	ABC transporter signature motif; other site
85569002326	Walker B; other site
85569002327	D-loop; other site
85569002328	H-loop/switch region; other site
85569002329	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569002330	Walker A/P-loop; other site
85569002331	ATP binding site [chemical binding]; other site
85569002332	Q-loop/lid; other site
85569002333	ABC transporter signature motif; other site
85569002334	Walker B; other site
85569002335	D-loop; other site
85569002336	H-loop/switch region; other site
85569002337	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
85569002338	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
85569002339	molybdenum-pterin binding domain; Region: Mop; TIGR00638
85569002340	TOBE domain; Region: TOBE; pfam03459
85569002341	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
85569002342	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
85569002343	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
85569002344	substrate binding pocket [chemical binding]; other site
85569002345	membrane-bound complex binding site; other site
85569002346	hinge residues; other site
85569002347	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
85569002348	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569002349	dimer interface [polypeptide binding]; other site
85569002350	conserved gate region; other site
85569002351	putative PBP binding loops; other site
85569002352	ABC-ATPase subunit interface; other site
85569002353	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
85569002354	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569002355	Walker A/P-loop; other site
85569002356	ATP binding site [chemical binding]; other site
85569002357	Q-loop/lid; other site
85569002358	ABC transporter signature motif; other site
85569002359	Walker B; other site
85569002360	D-loop; other site
85569002361	H-loop/switch region; other site
85569002362	molybdenum-pterin binding domain; Region: Mop; TIGR00638
85569002363	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
85569002364	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569002365	active site
85569002366	motif I; other site
85569002367	motif II; other site
85569002368	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
85569002369	S-adenosyl-l-methionine hydroxide adenosyltransferase; Region: SAM_adeno_trans; cl17774
85569002370	6-phosphogluconolactonase; Provisional; Region: PRK11028
85569002371	acyl-CoA thioesterase; Provisional; Region: PRK10531
85569002372	Pectinesterase; Region: Pectinesterase; cl01911
85569002373	imidazolonepropionase; Validated; Region: PRK09356
85569002374	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
85569002375	active site
85569002376	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
85569002377	putative active site [active]
85569002378	putative metal binding site [ion binding]; other site
85569002379	histidine utilization repressor; Provisional; Region: PRK14999
85569002380	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569002381	DNA-binding site [nucleotide binding]; DNA binding site
85569002382	UTRA domain; Region: UTRA; pfam07702
85569002383	urocanate hydratase; Provisional; Region: PRK05414
85569002384	Aromatic amino acid lyase; Region: Lyase_aromatic; pfam00221
85569002385	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
85569002386	active sites [active]
85569002387	tetramer interface [polypeptide binding]; other site
85569002388	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
85569002389	substrate binding site [chemical binding]; other site
85569002390	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
85569002391	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
85569002392	inhibitor-cofactor binding pocket; inhibition site
85569002393	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569002394	catalytic residue [active]
85569002395	biotin synthase; Provisional; Region: PRK15108
85569002396	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569002397	FeS/SAM binding site; other site
85569002398	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
85569002399	8-amino-7-oxononanoate synthase; Region: bioF; TIGR00858
85569002400	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
85569002401	substrate-cofactor binding pocket; other site
85569002402	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569002403	catalytic residue [active]
85569002404	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
85569002405	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569002406	S-adenosylmethionine binding site [chemical binding]; other site
85569002407	AAA domain; Region: AAA_26; pfam13500
85569002408	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
85569002409	excinuclease ABC subunit B; Provisional; Region: PRK05298
85569002410	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
85569002411	ATP binding site [chemical binding]; other site
85569002412	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
85569002413	nucleotide binding region [chemical binding]; other site
85569002414	ATP-binding site [chemical binding]; other site
85569002415	Ultra-violet resistance protein B; Region: UvrB; pfam12344
85569002416	UvrB/uvrC motif; Region: UVR; pfam02151
85569002417	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
85569002418	phosphate binding site [ion binding]; other site
85569002419	putative substrate binding pocket [chemical binding]; other site
85569002420	dimer interface [polypeptide binding]; other site
85569002421	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
85569002422	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569002423	FeS/SAM binding site; other site
85569002424	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
85569002425	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
85569002426	MPT binding site; other site
85569002427	trimer interface [polypeptide binding]; other site
85569002428	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
85569002429	trimer interface [polypeptide binding]; other site
85569002430	dimer interface [polypeptide binding]; other site
85569002431	putative active site [active]
85569002432	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
85569002433	MoaE interaction surface [polypeptide binding]; other site
85569002434	MoeB interaction surface [polypeptide binding]; other site
85569002435	thiocarboxylated glycine; other site
85569002436	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
85569002437	MoaE homodimer interface [polypeptide binding]; other site
85569002438	MoaD interaction [polypeptide binding]; other site
85569002439	active site residues [active]
85569002440	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
85569002441	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
85569002442	Predicted integral membrane protein [Function unknown]; Region: COG0392
85569002443	cardiolipin synthase 2; Provisional; Region: PRK11263
85569002444	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
85569002445	putative active site [active]
85569002446	catalytic site [active]
85569002447	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
85569002448	putative active site [active]
85569002449	catalytic site [active]
85569002450	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
85569002451	putative catalytic site [active]
85569002452	putative metal binding site [ion binding]; other site
85569002453	putative phosphate binding site [ion binding]; other site
85569002454	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
85569002455	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; cl19580
85569002456	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
85569002457	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
85569002458	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
85569002459	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
85569002460	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
85569002461	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
85569002462	Walker A/P-loop; other site
85569002463	ATP binding site [chemical binding]; other site
85569002464	Q-loop/lid; other site
85569002465	ABC transporter signature motif; other site
85569002466	Walker B; other site
85569002467	D-loop; other site
85569002468	H-loop/switch region; other site
85569002469	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
85569002470	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
85569002471	Walker A/P-loop; other site
85569002472	ATP binding site [chemical binding]; other site
85569002473	Q-loop/lid; other site
85569002474	ABC transporter signature motif; other site
85569002475	Walker B; other site
85569002476	D-loop; other site
85569002477	H-loop/switch region; other site
85569002478	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
85569002479	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
85569002480	HlyD family secretion protein; Region: HlyD_3; pfam13437
85569002481	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
85569002482	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
85569002483	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
85569002484	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
85569002485	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
85569002486	ATP binding site [chemical binding]; other site
85569002487	Mg++ binding site [ion binding]; other site
85569002488	motif III; other site
85569002489	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
85569002490	nucleotide binding region [chemical binding]; other site
85569002491	ATP-binding site [chemical binding]; other site
85569002492	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
85569002493	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
85569002494	DEAD_2; Region: DEAD_2; pfam06733
85569002495	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
85569002496	glycosyl transferase family protein; Provisional; Region: PRK08136
85569002497	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
85569002498	hypothetical protein; Provisional; Region: PRK10259
85569002499	hypothetical protein; Provisional; Region: PRK11019
85569002500	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
85569002501	putative mechanosensitive channel protein; Provisional; Region: PRK11465
85569002502	Mechanosensitive ion channel; Region: MS_channel; pfam00924
85569002503	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
85569002504	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
85569002505	Walker A/P-loop; other site
85569002506	ATP binding site [chemical binding]; other site
85569002507	Q-loop/lid; other site
85569002508	ABC transporter signature motif; other site
85569002509	Walker B; other site
85569002510	D-loop; other site
85569002511	H-loop/switch region; other site
85569002512	glutamine ABC transporter permease protein; Reviewed; Region: glnP; PRK09494
85569002513	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569002514	dimer interface [polypeptide binding]; other site
85569002515	conserved gate region; other site
85569002516	putative PBP binding loops; other site
85569002517	ABC-ATPase subunit interface; other site
85569002518	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
85569002519	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
85569002520	substrate binding pocket [chemical binding]; other site
85569002521	membrane-bound complex binding site; other site
85569002522	hinge residues; other site
85569002523	Ferritin-like domain; Region: Ferritin; pfam00210
85569002524	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
85569002525	dimerization interface [polypeptide binding]; other site
85569002526	DPS ferroxidase diiron center [ion binding]; other site
85569002527	ion pore; other site
85569002528	threonine and homoserine efflux system; Provisional; Region: PRK10532
85569002529	EamA-like transporter family; Region: EamA; pfam00892
85569002530	outer membrane protein X; Provisional; Region: ompX; PRK09408
85569002531	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
85569002532	Sulfatase; Region: Sulfatase; pfam00884
85569002533	manganese transport regulator MntR; Provisional; Region: PRK11050
85569002534	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
85569002535	Iron dependent repressor, metal binding and dimerization domain; Region: Fe_dep_repr_C; pfam02742
85569002536	L,D-transpeptidase; Provisional; Region: PRK10260
85569002537	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
85569002538	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
85569002539	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
85569002540	ABC transporter; Region: ABC_tran_2; pfam12848
85569002541	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
85569002542	Domain of unknown function (DUF4261); Region: DUF4261; pfam14080
85569002543	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569002544	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
85569002545	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
85569002546	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569002547	active site
85569002548	motif I; other site
85569002549	motif II; other site
85569002550	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
85569002551	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
85569002552	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
85569002553	dimer interface [polypeptide binding]; other site
85569002554	active site
85569002555	glycine loop; other site
85569002556	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
85569002557	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl18962
85569002558	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
85569002559	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
85569002560	ATP binding site [chemical binding]; other site
85569002561	substrate interface [chemical binding]; other site
85569002562	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
85569002563	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
85569002564	dimer interface [polypeptide binding]; other site
85569002565	putative functional site; other site
85569002566	putative MPT binding site; other site
85569002567	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
85569002568	catalytic nucleophile [active]
85569002569	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
85569002570	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
85569002571	Walker A/P-loop; other site
85569002572	ATP binding site [chemical binding]; other site
85569002573	Q-loop/lid; other site
85569002574	ABC transporter signature motif; other site
85569002575	Walker B; other site
85569002576	D-loop; other site
85569002577	H-loop/switch region; other site
85569002578	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
85569002579	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
85569002580	Walker A/P-loop; other site
85569002581	ATP binding site [chemical binding]; other site
85569002582	Q-loop/lid; other site
85569002583	ABC transporter signature motif; other site
85569002584	Walker B; other site
85569002585	D-loop; other site
85569002586	H-loop/switch region; other site
85569002587	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
85569002588	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
85569002589	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
85569002590	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
85569002591	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569002592	dimer interface [polypeptide binding]; other site
85569002593	conserved gate region; other site
85569002594	putative PBP binding loops; other site
85569002595	ABC-ATPase subunit interface; other site
85569002596	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
85569002597	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
85569002598	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569002599	dimer interface [polypeptide binding]; other site
85569002600	conserved gate region; other site
85569002601	putative PBP binding loops; other site
85569002602	ABC-ATPase subunit interface; other site
85569002603	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
85569002604	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
85569002605	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569002606	FeS/SAM binding site; other site
85569002607	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
85569002608	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
85569002609	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
85569002610	Ligand binding site [chemical binding]; other site
85569002611	electron transfer flavoprotein subunit alpha; Provisional; Region: PLN00022
85569002612	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
85569002613	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
85569002614	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
85569002615	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
85569002616	active site
85569002617	Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644
85569002618	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569002619	Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187
85569002620	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569002621	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569002622	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_1; cd08421
85569002623	putative dimerization interface [polypeptide binding]; other site
85569002624	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
85569002625	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
85569002626	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
85569002627	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
85569002628	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
85569002629	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; cl19645
85569002630	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
85569002631	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
85569002632	putative C-terminal domain interface [polypeptide binding]; other site
85569002633	putative GSH binding site (G-site) [chemical binding]; other site
85569002634	putative dimer interface [polypeptide binding]; other site
85569002635	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
85569002636	N-terminal domain interface [polypeptide binding]; other site
85569002637	dimer interface [polypeptide binding]; other site
85569002638	substrate binding pocket (H-site) [chemical binding]; other site
85569002639	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
85569002640	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
85569002641	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
85569002642	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
85569002643	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
85569002644	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
85569002645	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
85569002646	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
85569002647	active site
85569002648	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
85569002649	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569002650	putative substrate translocation pore; other site
85569002651	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
85569002652	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569002653	active site
85569002654	motif I; other site
85569002655	motif II; other site
85569002656	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569002657	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
85569002658	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569002659	putative substrate translocation pore; other site
85569002660	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3226
85569002661	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
85569002662	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
85569002663	putative transporter; Provisional; Region: PRK04972
85569002664	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
85569002665	TrkA-C domain; Region: TrkA_C; pfam02080
85569002666	TrkA-C domain; Region: TrkA_C; pfam02080
85569002667	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
85569002668	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
85569002669	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
85569002670	GSH binding site [chemical binding]; other site
85569002671	catalytic residues [active]
85569002672	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
85569002673	dimer interface [polypeptide binding]; other site
85569002674	FMN binding site [chemical binding]; other site
85569002675	NADPH bind site [chemical binding]; other site
85569002676	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
85569002677	RimK-like ATP-grasp domain; Region: RimK; pfam08443
85569002678	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
85569002679	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
85569002680	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
85569002681	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569002682	Walker A/P-loop; other site
85569002683	ATP binding site [chemical binding]; other site
85569002684	Q-loop/lid; other site
85569002685	ABC transporter signature motif; other site
85569002686	Walker B; other site
85569002687	D-loop; other site
85569002688	H-loop/switch region; other site
85569002689	TOBE domain; Region: TOBE_2; pfam08402
85569002690	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569002691	dimer interface [polypeptide binding]; other site
85569002692	conserved gate region; other site
85569002693	putative PBP binding loops; other site
85569002694	ABC-ATPase subunit interface; other site
85569002695	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
85569002696	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569002697	dimer interface [polypeptide binding]; other site
85569002698	conserved gate region; other site
85569002699	putative PBP binding loops; other site
85569002700	ABC-ATPase subunit interface; other site
85569002701	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
85569002702	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
85569002703	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569002704	S-adenosylmethionine binding site [chemical binding]; other site
85569002705	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
85569002706	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
85569002707	active site
85569002708	P-loop; other site
85569002709	phosphorylation site [posttranslational modification]
85569002710	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
85569002711	Sulfatase; Region: Sulfatase; cl19157
85569002712	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
85569002713	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
85569002714	substrate binding pocket [chemical binding]; other site
85569002715	membrane-bound complex binding site; other site
85569002716	hinge residues; other site
85569002717	arginine transporter permease subunit ArtM; Provisional; Region: artM; PRK11122
85569002718	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569002719	dimer interface [polypeptide binding]; other site
85569002720	conserved gate region; other site
85569002721	putative PBP binding loops; other site
85569002722	ABC-ATPase subunit interface; other site
85569002723	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
85569002724	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569002725	dimer interface [polypeptide binding]; other site
85569002726	conserved gate region; other site
85569002727	putative PBP binding loops; other site
85569002728	ABC-ATPase subunit interface; other site
85569002729	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
85569002730	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
85569002731	substrate binding pocket [chemical binding]; other site
85569002732	membrane-bound complex binding site; other site
85569002733	hinge residues; other site
85569002734	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
85569002735	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569002736	Walker A/P-loop; other site
85569002737	ATP binding site [chemical binding]; other site
85569002738	Q-loop/lid; other site
85569002739	ABC transporter signature motif; other site
85569002740	Walker B; other site
85569002741	D-loop; other site
85569002742	H-loop/switch region; other site
85569002743	putative lipoprotein; Provisional; Region: PRK10533
85569002744	hypothetical protein; Provisional; Region: PRK02877
85569002745	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
85569002746	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
85569002747	amidase catalytic site [active]
85569002748	Zn binding residues [ion binding]; other site
85569002749	substrate binding site [chemical binding]; other site
85569002750	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
85569002751	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
85569002752	NAD(P) binding site [chemical binding]; other site
85569002753	active site
85569002754	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
85569002755	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
85569002756	putative NAD(P) binding site [chemical binding]; other site
85569002757	putative active site [active]
85569002758	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
85569002759	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
85569002760	Beta-eliminating lyase; Region: Beta_elim_lyase; pfam01212
85569002761	tetramer interface [polypeptide binding]; other site
85569002762	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569002763	catalytic residue [active]
85569002764	pyruvate dehydrogenase; Provisional; Region: PRK09124
85569002765	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
85569002766	PYR/PP interface [polypeptide binding]; other site
85569002767	dimer interface [polypeptide binding]; other site
85569002768	tetramer interface [polypeptide binding]; other site
85569002769	TPP binding site [chemical binding]; other site
85569002770	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
85569002771	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
85569002772	TPP-binding site [chemical binding]; other site
85569002773	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
85569002774	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
85569002775	FAD binding pocket [chemical binding]; other site
85569002776	FAD binding motif [chemical binding]; other site
85569002777	phosphate binding motif [ion binding]; other site
85569002778	beta-alpha-beta structure motif; other site
85569002779	NAD binding pocket [chemical binding]; other site
85569002780	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
85569002781	catalytic loop [active]
85569002782	iron binding site [ion binding]; other site
85569002783	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
85569002784	cubane metal cluster [ion binding]; other site
85569002785	hybrid metal cluster; other site
85569002786	Predicted membrane protein [Function unknown]; Region: COG2431
85569002787	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
85569002788	AAA domain; Region: AAA_21; pfam13304
85569002789	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
85569002790	putative active site [active]
85569002791	putative metal-binding site [ion binding]; other site
85569002792	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
85569002793	macrolide transporter subunit MacA; Provisional; Region: PRK11578
85569002794	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
85569002795	HlyD family secretion protein; Region: HlyD_3; pfam13437
85569002796	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
85569002797	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
85569002798	Walker A/P-loop; other site
85569002799	ATP binding site [chemical binding]; other site
85569002800	Q-loop/lid; other site
85569002801	ABC transporter signature motif; other site
85569002802	Walker B; other site
85569002803	D-loop; other site
85569002804	H-loop/switch region; other site
85569002805	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
85569002806	FtsX-like permease family; Region: FtsX; pfam02687
85569002807	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
85569002808	DNA-binding site [nucleotide binding]; DNA binding site
85569002809	RNA-binding motif; other site
85569002810	Uncharacterized conserved protein [Function unknown]; Region: COG2127
85569002811	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
85569002812	Clp amino terminal domain; Region: Clp_N; pfam02861
85569002813	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569002814	Walker A motif; other site
85569002815	ATP binding site [chemical binding]; other site
85569002816	Walker B motif; other site
85569002817	arginine finger; other site
85569002818	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569002819	Walker A motif; other site
85569002820	ATP binding site [chemical binding]; other site
85569002821	Walker B motif; other site
85569002822	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
85569002823	Transposase IS200 like; Region: Y1_Tnp; pfam01797
85569002824	Integrase core domain; Region: rve; pfam00665
85569002825	Integrase core domain; Region: rve_3; pfam13683
85569002826	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
85569002827	Helix-turn-helix domain; Region: HTH_28; pfam13518
85569002828	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
85569002829	catalytic triad [active]
85569002830	dimer interface [polypeptide binding]; other site
85569002831	conserved cis-peptide bond; other site
85569002832	Pirin-related protein [General function prediction only]; Region: COG1741
85569002833	Pirin; Region: Pirin; pfam02678
85569002834	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
85569002835	LysR family transcriptional regulator; Provisional; Region: PRK14997
85569002836	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569002837	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
85569002838	putative effector binding pocket; other site
85569002839	putative dimerization interface [polypeptide binding]; other site
85569002840	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
85569002841	rRNA binding site [nucleotide binding]; other site
85569002842	predicted 30S ribosome binding site; other site
85569002843	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
85569002844	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
85569002845	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
85569002846	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
85569002847	Walker A/P-loop; other site
85569002848	ATP binding site [chemical binding]; other site
85569002849	Q-loop/lid; other site
85569002850	ABC transporter signature motif; other site
85569002851	Walker B; other site
85569002852	D-loop; other site
85569002853	H-loop/switch region; other site
85569002854	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
85569002855	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
85569002856	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569002857	Walker A/P-loop; other site
85569002858	ATP binding site [chemical binding]; other site
85569002859	Q-loop/lid; other site
85569002860	ABC transporter signature motif; other site
85569002861	Walker B; other site
85569002862	D-loop; other site
85569002863	H-loop/switch region; other site
85569002864	thioredoxin reductase; Provisional; Region: PRK10262
85569002865	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569002866	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
85569002867	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
85569002868	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
85569002869	putative DNA binding site [nucleotide binding]; other site
85569002870	putative Zn2+ binding site [ion binding]; other site
85569002871	AsnC family; Region: AsnC_trans_reg; pfam01037
85569002872	DNA translocase FtsK; Provisional; Region: PRK10263
85569002873	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569002874	variable surface protein Vir28; Provisional; Region: PTZ00249
85569002875	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
85569002876	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
85569002877	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
85569002878	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl19192
85569002879	recombination factor protein RarA; Reviewed; Region: PRK13342
85569002880	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569002881	Walker A motif; other site
85569002882	ATP binding site [chemical binding]; other site
85569002883	Walker B motif; other site
85569002884	arginine finger; other site
85569002885	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
85569002886	seryl-tRNA synthetase; Provisional; Region: PRK05431
85569002887	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
85569002888	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
85569002889	dimer interface [polypeptide binding]; other site
85569002890	active site
85569002891	motif 1; other site
85569002892	motif 2; other site
85569002893	motif 3; other site
85569002894	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
85569002895	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
85569002896	putative [Fe4-S4] binding site [ion binding]; other site
85569002897	putative molybdopterin cofactor binding site [chemical binding]; other site
85569002898	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
85569002899	putative molybdopterin cofactor binding site; other site
85569002900	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
85569002901	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
85569002902	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
85569002903	putative MFS family transporter protein; Provisional; Region: PRK03633
85569002904	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569002905	putative substrate translocation pore; other site
85569002906	inner membrane transporter YjeM; Provisional; Region: PRK15238
85569002907	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
85569002908	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569002909	FeS/SAM binding site; other site
85569002910	integrase; Provisional; Region: int; PHA02601
85569002911	pathogenicity island 1 protein SopD2; Provisional; Region: PRK15380
85569002912	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
85569002913	Pyruvate formate lyase 1; Region: PFL1; cd01678
85569002914	coenzyme A binding site [chemical binding]; other site
85569002915	active site
85569002916	catalytic residues [active]
85569002917	glycine loop; other site
85569002918	formate transporter; Provisional; Region: PRK10805
85569002919	uncharacterized domain; Region: TIGR00702
85569002920	Predicted membrane protein [Function unknown]; Region: COG2323
85569002921	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
85569002922	homodimer interface [polypeptide binding]; other site
85569002923	substrate-cofactor binding pocket; other site
85569002924	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569002925	catalytic residue [active]
85569002926	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
85569002927	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
85569002928	putative active site [active]
85569002929	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
85569002930	cytidylate kinase; Provisional; Region: cmk; PRK00023
85569002931	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
85569002932	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
85569002933	active site
85569002934	CMP-binding site; other site
85569002935	The sites determining sugar specificity; other site
85569002936	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
85569002937	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
85569002938	RNA binding site [nucleotide binding]; other site
85569002939	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
85569002940	RNA binding site [nucleotide binding]; other site
85569002941	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
85569002942	RNA binding site [nucleotide binding]; other site
85569002943	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
85569002944	RNA binding site [nucleotide binding]; other site
85569002945	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
85569002946	RNA binding site [nucleotide binding]; other site
85569002947	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
85569002948	RNA binding site [nucleotide binding]; other site
85569002949	Beta subunit of integration host factor (IHFB); Region: IHF_B; cd13836
85569002950	dimer interface [polypeptide binding]; other site
85569002951	DNA binding site [nucleotide binding]
85569002952	ComEC family competence protein; Provisional; Region: PRK11539
85569002953	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
85569002954	Competence protein; Region: Competence; pfam03772
85569002955	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
85569002956	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
85569002957	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
85569002958	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
85569002959	Walker A/P-loop; other site
85569002960	ATP binding site [chemical binding]; other site
85569002961	Q-loop/lid; other site
85569002962	ABC transporter signature motif; other site
85569002963	Walker B; other site
85569002964	D-loop; other site
85569002965	H-loop/switch region; other site
85569002966	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
85569002967	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
85569002968	hypothetical protein; Provisional; Region: PRK11827
85569002969	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
85569002970	Ligand binding site; other site
85569002971	oligomer interface; other site
85569002972	hypothetical protein; Provisional; Region: PRK10593
85569002973	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
85569002974	putative active site [active]
85569002975	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
85569002976	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569002977	S-adenosylmethionine binding site [chemical binding]; other site
85569002978	condesin subunit F; Provisional; Region: PRK05260
85569002979	condesin subunit E; Provisional; Region: PRK05256
85569002980	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
85569002981	P-loop containing region of AAA domain; Region: AAA_29; cl17516
85569002982	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
85569002983	murein L,D-transpeptidase; Provisional; Region: PRK10594
85569002984	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
85569002985	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
85569002986	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
85569002987	Peptidase M15; Region: Peptidase_M15_3; cl01194
85569002988	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
85569002989	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
85569002990	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
85569002991	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569002992	homodimer interface [polypeptide binding]; other site
85569002993	catalytic residue [active]
85569002994	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
85569002995	trimer interface [polypeptide binding]; other site
85569002996	eyelet of channel; other site
85569002997	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
85569002998	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
85569002999	putative dimer interface [polypeptide binding]; other site
85569003000	putative anticodon binding site; other site
85569003001	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
85569003002	homodimer interface [polypeptide binding]; other site
85569003003	motif 1; other site
85569003004	motif 2; other site
85569003005	active site
85569003006	motif 3; other site
85569003007	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
85569003008	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
85569003009	putative DNA binding site [nucleotide binding]; other site
85569003010	putative Zn2+ binding site [ion binding]; other site
85569003011	AsnC family; Region: AsnC_trans_reg; pfam01037
85569003012	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
85569003013	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
85569003014	catalytic residue [active]
85569003015	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
85569003016	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
85569003017	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
85569003018	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
85569003019	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
85569003020	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
85569003021	active site
85569003022	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
85569003023	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
85569003024	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
85569003025	Int/Topo IB signature motif; other site
85569003026	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
85569003027	Protein of unknown function (DUF4060); Region: DUF4060; pfam13269
85569003028	RecT family; Region: RecT; pfam03837
85569003029	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
85569003030	exonuclease VIII; Reviewed; Region: PRK09709
85569003031	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
85569003032	Helix-turn-helix; Region: HTH_3; pfam01381
85569003033	Bacteriophage CII protein; Region: Phage_CII; pfam05269
85569003034	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
85569003035	primosomal protein DnaI; Provisional; Region: PRK02854
85569003036	putative replication protein; Provisional; Region: PRK12377
85569003037	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569003038	Walker A motif; other site
85569003039	ATP binding site [chemical binding]; other site
85569003040	Walker B motif; other site
85569003041	arginine finger; other site
85569003042	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
85569003043	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
85569003044	DinI-like family; Region: DinI; pfam06183
85569003045	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
85569003046	Antitermination protein; Region: Antiterm; pfam03589
85569003047	Antitermination protein; Region: Antiterm; pfam03589
85569003048	PipA protein; Region: PipA; pfam07108
85569003049	phage holin, lambda family; Region: holin_lambda; TIGR01594
85569003050	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
85569003051	catalytic residues [active]
85569003052	Bacteriophage Rz lysis protein; Region: Phage_lysis; pfam03245
85569003053	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
85569003054	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
85569003055	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
85569003056	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_1; cd07016
85569003057	oligomer interface [polypeptide binding]; other site
85569003058	active site residues [active]
85569003059	Mu-like prophage major head subunit gpT; Region: Mu-like_gpT; cl01826
85569003060	Uncharacterized conserved protein [Function unknown]; Region: COG5471
85569003061	ATP-binding sugar transporter from pro-phage; Region: Gifsy-2; pfam13856
85569003062	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
85569003063	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
85569003064	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
85569003065	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
85569003066	phage minor tail protein G; Region: phage_lambda_G; TIGR01674
85569003067	phage tail assembly protein T; Region: phage_lam_T; TIGR01715
85569003068	Phage-related minor tail protein [Function unknown]; Region: COG5281
85569003069	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
85569003070	phage tail tape measure protein, lambda family; Region: tape_meas_lam_C; TIGR01541
85569003071	Phage-related protein [Function unknown]; Region: COG4718
85569003072	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
85569003073	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
85569003074	E-class dimer interface [polypeptide binding]; other site
85569003075	P-class dimer interface [polypeptide binding]; other site
85569003076	active site
85569003077	Cu2+ binding site [ion binding]; other site
85569003078	Zn2+ binding site [ion binding]; other site
85569003079	Phage-related protein [Function unknown]; Region: gp18; COG4672
85569003080	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
85569003081	MPN+ (JAMM) motif; other site
85569003082	Zinc-binding site [ion binding]; other site
85569003083	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
85569003084	NlpC/P60 family; Region: NLPC_P60; cl17555
85569003085	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
85569003086	Phage-related protein, tail component [Function unknown]; Region: COG4723
85569003087	Phage-related protein, tail component [Function unknown]; Region: COG4733
85569003088	Phage-related protein, tail component [Function unknown]; Region: COG4733
85569003089	Putative phage tail protein; Region: Phage-tail_3; pfam13550
85569003090	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
85569003091	Interdomain contacts; other site
85569003092	Cytokine receptor motif; other site
85569003093	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
85569003094	Fibronectin type III protein; Region: DUF3672; pfam12421
85569003095	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
85569003096	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
85569003097	Phage Tail Collar Domain; Region: Collar; pfam07484
85569003098	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
85569003099	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
85569003100	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
85569003101	pathogenicity island 2 effector protein SseI; Provisional; Region: PRK15372
85569003102	Dermonecrotoxin of the Papain-like fold; Region: Tox-PLDMTX; pfam15645
85569003103	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
85569003104	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
85569003105	hypothetical protein; Provisional; Region: PRK09951
85569003106	DinI-like family; Region: DinI; cl11630
85569003107	aminopeptidase N; Provisional; Region: pepN; PRK14015
85569003108	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
85569003109	active site
85569003110	Zn binding site [ion binding]; other site
85569003111	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
85569003112	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
85569003113	quinone interaction residues [chemical binding]; other site
85569003114	active site
85569003115	catalytic residues [active]
85569003116	FMN binding site [chemical binding]; other site
85569003117	substrate binding site [chemical binding]; other site
85569003118	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
85569003119	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
85569003120	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
85569003121	MOSC domain; Region: MOSC; pfam03473
85569003122	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
85569003123	catalytic loop [active]
85569003124	iron binding site [ion binding]; other site
85569003125	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
85569003126	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
85569003127	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
85569003128	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569003129	S-adenosylmethionine binding site [chemical binding]; other site
85569003130	ABC transporter ATPase component; Reviewed; Region: PRK11147
85569003131	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
85569003132	ABC transporter; Region: ABC_tran_2; pfam12848
85569003133	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
85569003134	The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013
85569003135	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
85569003136	Paraquat-inducible protein A; Region: PqiA; pfam04403
85569003137	Paraquat-inducible protein A; Region: PqiA; pfam04403
85569003138	paraquat-inducible protein B; Provisional; Region: PRK10807
85569003139	mce related protein; Region: MCE; pfam02470
85569003140	mce related protein; Region: MCE; pfam02470
85569003141	mce related protein; Region: MCE; pfam02470
85569003142	Biogenesis of lysosome-related organelles complex-1 subunit 2; Region: BLOC1_2; pfam10046
85569003143	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
85569003144	ribosome modulation factor; Provisional; Region: PRK14563
85569003145	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
85569003146	active site 1 [active]
85569003147	dimer interface [polypeptide binding]; other site
85569003148	active site 2 [active]
85569003149	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
85569003150	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
85569003151	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
85569003152	outer membrane protein A; Reviewed; Region: PRK10808
85569003153	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
85569003154	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
85569003155	ligand binding site [chemical binding]; other site
85569003156	cell division inhibitor SulA; Region: sula; TIGR00623
85569003157	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
85569003158	TfoX C-terminal domain; Region: TfoX_C; pfam04994
85569003159	TIGR01666 family membrane protein; Region: YCCS
85569003160	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
85569003161	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
85569003162	Predicted membrane protein [Function unknown]; Region: COG3304
85569003163	Domain of unknown function (DUF307); Region: DUF307; pfam03733
85569003164	Domain of unknown function (DUF307); Region: DUF307; pfam03733
85569003165	DNA helicase IV; Provisional; Region: helD; PRK11054
85569003166	DNA helicase IV / RNA helicase N terminal; Region: Helicase_IV_N; pfam12462
85569003167	Part of AAA domain; Region: AAA_19; pfam13245
85569003168	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
85569003169	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
85569003170	active site
85569003171	dimer interfaces [polypeptide binding]; other site
85569003172	catalytic residues [active]
85569003173	hypothetical protein; Provisional; Region: PRK03641
85569003174	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
85569003175	heat shock protein HspQ; Provisional; Region: PRK14129
85569003176	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
85569003177	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
85569003178	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
85569003179	putative RNA binding site [nucleotide binding]; other site
85569003180	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569003181	S-adenosylmethionine binding site [chemical binding]; other site
85569003182	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
85569003183	substrate binding site [chemical binding]; other site
85569003184	Cupin domain; Region: Cupin_2; cl17218
85569003185	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
85569003186	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569003187	acylphosphatase; Provisional; Region: PRK14426
85569003188	sulfur transfer protein TusE; Provisional; Region: PRK11508
85569003189	YccA-like proteins; Region: YccA_like; cd10433
85569003190	PipA protein; Region: PipA; pfam07108
85569003191	secreted effector protein PipB; Provisional; Region: PRK15197
85569003192	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
85569003193	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
85569003194	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
85569003195	type III secretion chaperone protein SigE; Provisional; Region: PRK15202
85569003196	Enterobacterial virulence protein IpgD; Region: IpgD; pfam05925
85569003197	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
85569003198	Dipeptidase [Amino acid transport and metabolism]; Region: PepD; COG4690
85569003199	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
85569003200	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569003201	dimerization interface [polypeptide binding]; other site
85569003202	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569003203	dimer interface [polypeptide binding]; other site
85569003204	phosphorylation site [posttranslational modification]
85569003205	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569003206	ATP binding site [chemical binding]; other site
85569003207	Mg2+ binding site [ion binding]; other site
85569003208	G-X-G motif; other site
85569003209	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
85569003210	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569003211	active site
85569003212	phosphorylation site [posttranslational modification]
85569003213	intermolecular recognition site; other site
85569003214	dimerization interface [polypeptide binding]; other site
85569003215	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
85569003216	DNA binding site [nucleotide binding]
85569003217	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
85569003218	active site
85569003219	homotetramer interface [polypeptide binding]; other site
85569003220	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
85569003221	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
85569003222	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
85569003223	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
85569003224	Transcriptional regulators [Transcription]; Region: MarR; COG1846
85569003225	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
85569003226	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
85569003227	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
85569003228	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
85569003229	NAD binding site [chemical binding]; other site
85569003230	catalytic residues [active]
85569003231	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
85569003232	putative active site [active]
85569003233	putative metal binding site [ion binding]; other site
85569003234	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
85569003235	putative substrate binding pocket [chemical binding]; other site
85569003236	trimer interface [polypeptide binding]; other site
85569003237	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
85569003238	2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Region: HpaI; TIGR02311
85569003239	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
85569003240	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569003241	putative substrate translocation pore; other site
85569003242	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
85569003243	Cupin domain; Region: Cupin_2; pfam07883
85569003244	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569003245	Metal-dependent hydrolases of the beta-lactamase superfamily III [General function prediction only]; Region: ElaC; COG1234
85569003246	anti-adapter protein IraM; Provisional; Region: PRK09919
85569003247	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
85569003248	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
85569003249	HSP70 interaction site [polypeptide binding]; other site
85569003250	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
85569003251	substrate binding site [polypeptide binding]; other site
85569003252	dimer interface [polypeptide binding]; other site
85569003253	Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4233
85569003254	Thiol:disulfide interchange protein [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4232
85569003255	Sulfite exporter TauE/SafE; Region: TauE; cl19196
85569003256	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
85569003257	DsbD alpha interface [polypeptide binding]; other site
85569003258	catalytic residues [active]
85569003259	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
85569003260	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
85569003261	DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC...; Region: DsbA_Com1_like; cd03023
85569003262	catalytic residues [active]
85569003263	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
85569003264	catalytic residues [active]
85569003265	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
85569003266	catalytic core [active]
85569003267	hypothetical protein; Provisional; Region: PRK10174
85569003268	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
85569003269	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
85569003270	General stress protein [General function prediction only]; Region: GsiB; COG3729
85569003271	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
85569003272	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
85569003273	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
85569003274	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
85569003275	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
85569003276	Predicted transcriptional regulator [Transcription]; Region: COG3905
85569003277	DNA-binding domain of Proline dehydrogenase; Region: Pro_dh-DNA_bdg; pfam14850
85569003278	Proline dehydrogenase; Region: Pro_dh; pfam01619
85569003279	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
85569003280	Glutamate binding site [chemical binding]; other site
85569003281	NAD binding site [chemical binding]; other site
85569003282	catalytic residues [active]
85569003283	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
85569003284	Na binding site [ion binding]; other site
85569003285	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
85569003286	hypothetical protein; Provisional; Region: PRK10536
85569003287	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
85569003288	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
85569003289	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
85569003290	putative active site [active]
85569003291	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
85569003292	Na binding site [ion binding]; other site
85569003293	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
85569003294	putative active site cavity [active]
85569003295	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
85569003296	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
85569003297	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
85569003298	putative sialic acid transporter; Provisional; Region: PRK12307
85569003299	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569003300	putative substrate translocation pore; other site
85569003301	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
85569003302	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
85569003303	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
85569003304	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
85569003305	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
85569003306	putative ligand binding site [chemical binding]; other site
85569003307	NAD binding site [chemical binding]; other site
85569003308	dimerization interface [polypeptide binding]; other site
85569003309	catalytic site [active]
85569003310	putative hydrolase; Validated; Region: PRK09248
85569003311	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
85569003312	active site
85569003313	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
85569003314	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
85569003315	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
85569003316	curli assembly protein CsgF; Provisional; Region: PRK10050
85569003317	curli assembly protein CsgE; Provisional; Region: PRK10386
85569003318	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
85569003319	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569003320	DNA binding residues [nucleotide binding]
85569003321	dimerization interface [polypeptide binding]; other site
85569003322	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
85569003323	Curlin associated repeat; Region: Curlin_rpt; pfam07012
85569003324	Curlin associated repeat; Region: Curlin_rpt; pfam07012
85569003325	major curlin subunit; Provisional; Region: csgA; PRK10051
85569003326	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
85569003327	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
85569003328	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
85569003329	putative ADP-ribose binding site [chemical binding]; other site
85569003330	putative active site [active]
85569003331	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
85569003332	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
85569003333	putative active site [active]
85569003334	catalytic site [active]
85569003335	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
85569003336	putative active site [active]
85569003337	catalytic site [active]
85569003338	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
85569003339	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
85569003340	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
85569003341	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
85569003342	Ligand binding site; other site
85569003343	DXD motif; other site
85569003344	lipoprotein; Provisional; Region: PRK10175
85569003345	secY/secA suppressor protein; Provisional; Region: PRK11467
85569003346	drug efflux system protein MdtG; Provisional; Region: PRK09874
85569003347	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569003348	putative substrate translocation pore; other site
85569003349	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
85569003350	putative acyl-acceptor binding pocket; other site
85569003351	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
85569003352	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
85569003353	active site residue [active]
85569003354	hypothetical protein; Provisional; Region: PRK03757
85569003355	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
85569003356	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
85569003357	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
85569003358	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
85569003359	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
85569003360	DNA damage-inducible protein I; Provisional; Region: PRK10597
85569003361	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
85569003362	active site
85569003363	substrate binding pocket [chemical binding]; other site
85569003364	dimer interface [polypeptide binding]; other site
85569003365	lipoprotein; Provisional; Region: PRK10598
85569003366	glutaredoxin 2; Provisional; Region: PRK10387
85569003367	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
85569003368	C-terminal domain interface [polypeptide binding]; other site
85569003369	GSH binding site (G-site) [chemical binding]; other site
85569003370	catalytic residues [active]
85569003371	putative dimer interface [polypeptide binding]; other site
85569003372	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
85569003373	N-terminal domain interface [polypeptide binding]; other site
85569003374	multidrug resistance protein MdtH; Provisional; Region: PRK11646
85569003375	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569003376	putative substrate translocation pore; other site
85569003377	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
85569003378	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
85569003379	hypothetical protein; Provisional; Region: PRK11239
85569003380	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
85569003381	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
85569003382	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
85569003383	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
85569003384	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
85569003385	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
85569003386	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
85569003387	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
85569003388	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
85569003389	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
85569003390	flagellar basal body rod protein FlgB; Provisional; Region: flgB; cl19173
85569003391	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
85569003392	flagellar basal body rod protein FlgB; Provisional; Region: flgB; cl19173
85569003393	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
85569003394	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
85569003395	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
85569003396	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
85569003397	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
85569003398	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
85569003399	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
85569003400	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
85569003401	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
85569003402	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
85569003403	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
85569003404	flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12694
85569003405	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
85569003406	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
85569003407	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
85569003408	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
85569003409	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
85569003410	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
85569003411	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
85569003412	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
85569003413	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
85569003414	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
85569003415	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
85569003416	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
85569003417	ribonuclease E; Reviewed; Region: rne; PRK10811
85569003418	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
85569003419	homodimer interface [polypeptide binding]; other site
85569003420	oligonucleotide binding site [chemical binding]; other site
85569003421	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
85569003422	Protein of unknown function (DUF3157); Region: DUF3157; pfam11355
85569003423	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
85569003424	Protein of unknown function (DUF2655); Region: DUF2655; pfam10848
85569003425	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
85569003426	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
85569003427	RNA binding surface [nucleotide binding]; other site
85569003428	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
85569003429	active site
85569003430	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
85569003431	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
85569003432	active site
85569003433	dimer interface [polypeptide binding]; other site
85569003434	hypothetical protein; Provisional; Region: PRK11193
85569003435	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
85569003436	putative phosphate acyltransferase; Provisional; Region: PRK05331
85569003437	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
85569003438	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
85569003439	dimer interface [polypeptide binding]; other site
85569003440	active site
85569003441	CoA binding pocket [chemical binding]; other site
85569003442	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
85569003443	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
85569003444	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
85569003445	NAD(P) binding site [chemical binding]; other site
85569003446	homotetramer interface [polypeptide binding]; other site
85569003447	homodimer interface [polypeptide binding]; other site
85569003448	active site
85569003449	acyl carrier protein; Provisional; Region: acpP; PRK00982
85569003450	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
85569003451	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
85569003452	dimer interface [polypeptide binding]; other site
85569003453	active site
85569003454	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
85569003455	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569003456	catalytic residue [active]
85569003457	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
85569003458	dimerization interface [polypeptide binding]; other site
85569003459	thymidylate kinase; Validated; Region: tmk; PRK00698
85569003460	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
85569003461	TMP-binding site; other site
85569003462	ATP-binding site [chemical binding]; other site
85569003463	DNA polymerase III subunit delta'; Validated; Region: PRK07993
85569003464	DNA polymerase III subunit delta'; Validated; Region: PRK08485
85569003465	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
85569003466	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
85569003467	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
85569003468	active site
85569003469	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
85569003470	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
85569003471	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
85569003472	active site turn [active]
85569003473	phosphorylation site [posttranslational modification]
85569003474	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
85569003475	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
85569003476	N-terminal plug; other site
85569003477	ligand-binding site [chemical binding]; other site
85569003478	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
85569003479	nucleotide binding site/active site [active]
85569003480	HIT family signature motif; other site
85569003481	catalytic residue [active]
85569003482	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
85569003483	putative dimer interface [polypeptide binding]; other site
85569003484	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
85569003485	Phosphotransferase enzyme family; Region: APH; pfam01636
85569003486	active site
85569003487	ATP binding site [chemical binding]; other site
85569003488	thiamine kinase; Provisional; Region: thiK; PRK10271
85569003489	substrate binding site [chemical binding]; other site
85569003490	beta-hexosaminidase; Provisional; Region: PRK05337
85569003491	hypothetical protein; Provisional; Region: PRK04940
85569003492	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
85569003493	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
85569003494	hypothetical protein; Provisional; Region: PRK11280
85569003495	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
85569003496	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
85569003497	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cl00532
85569003498	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
85569003499	L,D-transpeptidase; Provisional; Region: PRK10260
85569003500	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
85569003501	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
85569003502	transcription-repair coupling factor; Provisional; Region: PRK10689
85569003503	Bifunctional transglycosylase second domain; Region: UB2H; pfam14814
85569003504	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
85569003505	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
85569003506	ATP binding site [chemical binding]; other site
85569003507	putative Mg++ binding site [ion binding]; other site
85569003508	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
85569003509	nucleotide binding region [chemical binding]; other site
85569003510	ATP-binding site [chemical binding]; other site
85569003511	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
85569003512	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
85569003513	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
85569003514	FtsX-like permease family; Region: FtsX; pfam02687
85569003515	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
85569003516	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
85569003517	Walker A/P-loop; other site
85569003518	ATP binding site [chemical binding]; other site
85569003519	Q-loop/lid; other site
85569003520	ABC transporter signature motif; other site
85569003521	Walker B; other site
85569003522	D-loop; other site
85569003523	H-loop/switch region; other site
85569003524	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
85569003525	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
85569003526	FtsX-like permease family; Region: FtsX; pfam02687
85569003527	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
85569003528	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
85569003529	nucleotide binding site [chemical binding]; other site
85569003530	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
85569003531	NAD+ binding site [chemical binding]; other site
85569003532	substrate binding site [chemical binding]; other site
85569003533	Zn binding site [ion binding]; other site
85569003534	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
85569003535	spermidine/putrescine ABC transporter membrane protein; Reviewed; Region: potC; PRK09500
85569003536	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569003537	dimer interface [polypeptide binding]; other site
85569003538	conserved gate region; other site
85569003539	putative PBP binding loops; other site
85569003540	ABC-ATPase subunit interface; other site
85569003541	secreted effector protein SifA; Reviewed; Region: sifA; PRK09498
85569003542	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
85569003543	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569003544	dimer interface [polypeptide binding]; other site
85569003545	conserved gate region; other site
85569003546	putative PBP binding loops; other site
85569003547	ABC-ATPase subunit interface; other site
85569003548	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
85569003549	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
85569003550	Walker A/P-loop; other site
85569003551	ATP binding site [chemical binding]; other site
85569003552	Q-loop/lid; other site
85569003553	ABC transporter signature motif; other site
85569003554	Walker B; other site
85569003555	D-loop; other site
85569003556	H-loop/switch region; other site
85569003557	TOBE domain; Region: TOBE_2; pfam08402
85569003558	Uncharacterized conserved protein [Function unknown]; Region: COG2850
85569003559	sensor protein PhoQ; Provisional; Region: PRK10815
85569003560	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
85569003561	HAMP domain; Region: HAMP; pfam00672
85569003562	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
85569003563	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569003564	ATP binding site [chemical binding]; other site
85569003565	Mg2+ binding site [ion binding]; other site
85569003566	G-X-G motif; other site
85569003567	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
85569003568	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569003569	active site
85569003570	phosphorylation site [posttranslational modification]
85569003571	intermolecular recognition site; other site
85569003572	dimerization interface [polypeptide binding]; other site
85569003573	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
85569003574	DNA binding site [nucleotide binding]
85569003575	adenylosuccinate lyase; Provisional; Region: PRK09285
85569003576	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
85569003577	tetramer interface [polypeptide binding]; other site
85569003578	active site
85569003579	putative lysogenization regulator; Reviewed; Region: PRK00218
85569003580	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
85569003581	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
85569003582	Ligand Binding Site [chemical binding]; other site
85569003583	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
85569003584	nudix motif; other site
85569003585	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
85569003586	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
85569003587	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
85569003588	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
85569003589	probable active site [active]
85569003590	isocitrate dehydrogenase; Reviewed; Region: PRK07006
85569003591	Protein of unknown function (DUF3626); Region: DUF3626; pfam12294
85569003592	DinI-like family; Region: DinI; pfam06183
85569003593	Ricin-type beta-trefoil; Region: RICIN; smart00458
85569003594	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
85569003595	putative sugar binding sites [chemical binding]; other site
85569003596	Q-X-W motif; other site
85569003597	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
85569003598	DNA-binding site [nucleotide binding]; DNA binding site
85569003599	RNA-binding motif; other site
85569003600	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
85569003601	lysozyme inhibitor; Provisional; Region: PRK13791
85569003602	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
85569003603	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
85569003604	putative dimer interface [polypeptide binding]; other site
85569003605	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
85569003606	BNR repeat-like domain; Region: BNR_2; pfam13088
85569003607	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
85569003608	TRL-like protein family; Region: TRL; pfam13146
85569003609	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
85569003610	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
85569003611	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
85569003612	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569003613	dimer interface [polypeptide binding]; other site
85569003614	conserved gate region; other site
85569003615	putative PBP binding loops; other site
85569003616	ABC-ATPase subunit interface; other site
85569003617	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
85569003618	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569003619	dimer interface [polypeptide binding]; other site
85569003620	conserved gate region; other site
85569003621	putative PBP binding loops; other site
85569003622	ABC-ATPase subunit interface; other site
85569003623	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569003624	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
85569003625	Walker A/P-loop; other site
85569003626	ATP binding site [chemical binding]; other site
85569003627	Q-loop/lid; other site
85569003628	ABC transporter signature motif; other site
85569003629	Walker B; other site
85569003630	D-loop; other site
85569003631	H-loop/switch region; other site
85569003632	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569003633	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
85569003634	Walker A/P-loop; other site
85569003635	ATP binding site [chemical binding]; other site
85569003636	Q-loop/lid; other site
85569003637	ABC transporter signature motif; other site
85569003638	Walker B; other site
85569003639	D-loop; other site
85569003640	H-loop/switch region; other site
85569003641	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
85569003642	Mechanosensitive ion channel; Region: MS_channel; pfam00924
85569003643	Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026
85569003644	dimerization interface [polypeptide binding]; other site
85569003645	zinc/cadmium-binding protein; Provisional; Region: PRK10306
85569003646	aminoglycoside resistance protein; Provisional; Region: PRK13746
85569003647	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
85569003648	active site
85569003649	NTP binding site [chemical binding]; other site
85569003650	metal binding triad [ion binding]; metal-binding site
85569003651	antibiotic binding site [chemical binding]; other site
85569003652	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
85569003653	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
85569003654	DNA binding residues [nucleotide binding]
85569003655	transcriptional regulator MirA; Provisional; Region: PRK15043
85569003656	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
85569003657	DNA binding residues [nucleotide binding]
85569003658	dimer interface [polypeptide binding]; other site
85569003659	Pleckstrin homology-like domain; Region: PH-like; cl17171
85569003660	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
85569003661	chorismate mutase; Provisional; Region: PRK08055
85569003662	leucine export protein LeuE; Provisional; Region: PRK10958
85569003663	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
85569003664	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
85569003665	Uncharacterized conserved protein [Function unknown]; Region: COG3189
85569003666	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
85569003667	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569003668	putative substrate translocation pore; other site
85569003669	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
85569003670	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
85569003671	Predicted membrane protein [Function unknown]; Region: COG2707
85569003672	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
85569003673	putative deacylase active site [active]
85569003674	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
85569003675	metal binding site [ion binding]; metal-binding site
85569003676	active site
85569003677	I-site; other site
85569003678	hypothetical protein; Provisional; Region: PRK05325
85569003679	PrkA family serine protein kinase; Provisional; Region: PRK15455
85569003680	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569003681	Walker A motif; other site
85569003682	ATP binding site [chemical binding]; other site
85569003683	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
85569003684	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
85569003685	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
85569003686	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569003687	FeS/SAM binding site; other site
85569003688	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
85569003689	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
85569003690	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
85569003691	active site
85569003692	catalytic tetrad [active]
85569003693	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
85569003694	active site
85569003695	phosphate binding residues; other site
85569003696	catalytic residues [active]
85569003697	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
85569003698	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
85569003699	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
85569003700	methionine sulfoxide reductase B; Provisional; Region: PRK00222
85569003701	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
85569003702	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
85569003703	catalytic triad [active]
85569003704	metal binding site [ion binding]; metal-binding site
85569003705	conserved cis-peptide bond; other site
85569003706	cytoplasmic asparaginase I; Provisional; Region: ansA; PRK09461
85569003707	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
85569003708	active site
85569003709	homodimer interface [polypeptide binding]; other site
85569003710	protease 4; Provisional; Region: PRK10949
85569003711	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
85569003712	tandem repeat interface [polypeptide binding]; other site
85569003713	oligomer interface [polypeptide binding]; other site
85569003714	active site residues [active]
85569003715	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
85569003716	tandem repeat interface [polypeptide binding]; other site
85569003717	oligomer interface [polypeptide binding]; other site
85569003718	active site residues [active]
85569003719	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
85569003720	putative FMN binding site [chemical binding]; other site
85569003721	selenophosphate synthetase; Provisional; Region: PRK00943
85569003722	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
85569003723	dimerization interface [polypeptide binding]; other site
85569003724	putative ATP binding site [chemical binding]; other site
85569003725	DNA topoisomerase III; Provisional; Region: PRK07726
85569003726	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
85569003727	active site
85569003728	putative interdomain interaction site [polypeptide binding]; other site
85569003729	putative metal-binding site [ion binding]; other site
85569003730	putative nucleotide binding site [chemical binding]; other site
85569003731	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
85569003732	domain I; other site
85569003733	DNA binding groove [nucleotide binding]
85569003734	phosphate binding site [ion binding]; other site
85569003735	domain II; other site
85569003736	domain III; other site
85569003737	nucleotide binding site [chemical binding]; other site
85569003738	catalytic site [active]
85569003739	domain IV; other site
85569003740	glutamate dehydrogenase; Provisional; Region: PRK09414
85569003741	Glu/Leu/Phe/Val dehydrogenase, dimerization domain; Region: ELFV_dehydrog_N; pfam02812
85569003742	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
85569003743	NAD(P) binding site [chemical binding]; other site
85569003744	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
85569003745	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
85569003746	active site
85569003747	8-oxo-dGMP binding site [chemical binding]; other site
85569003748	nudix motif; other site
85569003749	metal binding site [ion binding]; metal-binding site
85569003750	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
85569003751	putative catalytic site [active]
85569003752	putative phosphate binding site [ion binding]; other site
85569003753	active site
85569003754	metal binding site A [ion binding]; metal-binding site
85569003755	DNA binding site [nucleotide binding]
85569003756	putative AP binding site [nucleotide binding]; other site
85569003757	putative metal binding site B [ion binding]; other site
85569003758	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
85569003759	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
85569003760	inhibitor-cofactor binding pocket; inhibition site
85569003761	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569003762	catalytic residue [active]
85569003763	arginine succinyltransferase; Provisional; Region: PRK10456
85569003764	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
85569003765	NAD(P) binding site [chemical binding]; other site
85569003766	catalytic residues [active]
85569003767	succinylarginine dihydrolase; Provisional; Region: PRK13281
85569003768	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
85569003769	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
85569003770	putative active site [active]
85569003771	Zn binding site [ion binding]; other site
85569003772	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
85569003773	dimer interface [polypeptide binding]; other site
85569003774	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
85569003775	homodimer interface [polypeptide binding]; other site
85569003776	NAD binding pocket [chemical binding]; other site
85569003777	ATP binding pocket [chemical binding]; other site
85569003778	Mg binding site [ion binding]; other site
85569003779	active-site loop [active]
85569003780	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
85569003781	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
85569003782	active site
85569003783	P-loop; other site
85569003784	phosphorylation site [posttranslational modification]
85569003785	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
85569003786	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
85569003787	methionine cluster; other site
85569003788	active site
85569003789	phosphorylation site [posttranslational modification]
85569003790	metal binding site [ion binding]; metal-binding site
85569003791	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
85569003792	Cupin domain; Region: Cupin_2; cl17218
85569003793	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569003794	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
85569003795	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
85569003796	NAD binding site [chemical binding]; other site
85569003797	sugar binding site [chemical binding]; other site
85569003798	divalent metal binding site [ion binding]; other site
85569003799	tetramer (dimer of dimers) interface [polypeptide binding]; other site
85569003800	dimer interface [polypeptide binding]; other site
85569003801	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
85569003802	putative active site [active]
85569003803	YdjC motif; other site
85569003804	Mg binding site [ion binding]; other site
85569003805	putative homodimer interface [polypeptide binding]; other site
85569003806	Transposase IS200 like; Region: Y1_Tnp; pfam01797
85569003807	hydroperoxidase II; Provisional; Region: katE; PRK11249
85569003808	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
85569003809	tetramer interface [polypeptide binding]; other site
85569003810	heme binding pocket [chemical binding]; other site
85569003811	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
85569003812	domain interactions; other site
85569003813	cell division modulator; Provisional; Region: PRK10113
85569003814	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
85569003815	inner membrane protein; Provisional; Region: PRK11648
85569003816	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
85569003817	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
85569003818	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569003819	motif II; other site
85569003820	YniB-like protein; Region: YniB; pfam14002
85569003821	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3001
85569003822	Phosphotransferase enzyme family; Region: APH; pfam01636
85569003823	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
85569003824	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
85569003825	putative substrate binding site [chemical binding]; other site
85569003826	putative ATP binding site [chemical binding]; other site
85569003827	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
85569003828	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3528
85569003829	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
85569003830	active site
85569003831	substrate binding site [chemical binding]; other site
85569003832	Mg2+ binding site [ion binding]; other site
85569003833	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
85569003834	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
85569003835	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
85569003836	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
85569003837	active site
85569003838	dimer interface [polypeptide binding]; other site
85569003839	motif 1; other site
85569003840	motif 2; other site
85569003841	motif 3; other site
85569003842	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
85569003843	anticodon binding site; other site
85569003844	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
85569003845	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
85569003846	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
85569003847	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
85569003848	23S rRNA binding site [nucleotide binding]; other site
85569003849	L21 binding site [polypeptide binding]; other site
85569003850	L13 binding site [polypeptide binding]; other site
85569003851	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
85569003852	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
85569003853	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
85569003854	dimer interface [polypeptide binding]; other site
85569003855	motif 1; other site
85569003856	active site
85569003857	motif 2; other site
85569003858	motif 3; other site
85569003859	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
85569003860	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
85569003861	putative tRNA-binding site [nucleotide binding]; other site
85569003862	B3/4 domain; Region: B3_4; pfam03483
85569003863	tRNA synthetase B5 domain; Region: B5; smart00874
85569003864	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
85569003865	dimer interface [polypeptide binding]; other site
85569003866	motif 1; other site
85569003867	motif 3; other site
85569003868	motif 2; other site
85569003869	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
85569003870	Alpha subunit of integration host factor (IHFA); Region: IHF_A; cd13835
85569003871	DNA binding site [nucleotide binding]
85569003872	dimer interface [polypeptide binding]; other site
85569003873	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
85569003874	ABC-ATPase subunit  interface; other site
85569003875	dimer interface [polypeptide binding]; other site
85569003876	putative PBP binding regions; other site
85569003877	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
85569003878	catalytic residues [active]
85569003879	dimer interface [polypeptide binding]; other site
85569003880	ABC-type cobalamin transport system, ATPase component [Coenzyme metabolism]; Region: BtuD; COG4138
85569003881	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
85569003882	Walker A/P-loop; other site
85569003883	ATP binding site [chemical binding]; other site
85569003884	Q-loop/lid; other site
85569003885	ABC transporter signature motif; other site
85569003886	Walker B; other site
85569003887	D-loop; other site
85569003888	H-loop/switch region; other site
85569003889	NlpC/P60 family; Region: NLPC_P60; pfam00877
85569003890	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
85569003891	hypothetical protein; Validated; Region: PRK00029
85569003892	hypothetical protein; Provisional; Region: PRK10183
85569003893	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
85569003894	PEP synthetase regulatory protein; Provisional; Region: PRK05339
85569003895	phosphoenolpyruvate synthase; Validated; Region: PRK06464
85569003896	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
85569003897	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
85569003898	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
85569003899	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
85569003900	CoA binding site [chemical binding]; other site
85569003901	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
85569003902	acyl-activating enzyme (AAE) consensus motif; other site
85569003903	active site
85569003904	AMP binding site [chemical binding]; other site
85569003905	CoA binding site [chemical binding]; other site
85569003906	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
85569003907	oxidoreductase; Provisional; Region: PRK10015
85569003908	putative oxidoreductase FixC; Provisional; Region: PRK10157
85569003909	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
85569003910	Electron transfer flavoprotein domain; Region: ETF; pfam01012
85569003911	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
85569003912	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
85569003913	Ligand binding site [chemical binding]; other site
85569003914	Cupin domain; Region: Cupin_2; pfam07883
85569003915	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
85569003916	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
85569003917	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
85569003918	active site
85569003919	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
85569003920	Coenzyme A transferase; Region: CoA_trans; smart00882
85569003921	Coenzyme A transferase; Region: CoA_trans; cl17247
85569003922	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
85569003923	active site
85569003924	catalytic residue [active]
85569003925	dimer interface [polypeptide binding]; other site
85569003926	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
85569003927	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
85569003928	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
85569003929	shikimate binding site; other site
85569003930	NAD(P) binding site [chemical binding]; other site
85569003931	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569003932	putative transporter; Provisional; Region: PRK03699
85569003933	putative substrate translocation pore; other site
85569003934	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569003935	Major Facilitator Superfamily; Region: MFS_1; pfam07690
85569003936	putative substrate translocation pore; other site
85569003937	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
85569003938	putative inner membrane protein; Provisional; Region: PRK10983
85569003939	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
85569003940	FAD binding domain; Region: FAD_binding_4; pfam01565
85569003941	FAD linked oxidases, C-terminal domain; Region: FAD-oxidase_C; pfam02913
85569003942	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
85569003943	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
85569003944	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
85569003945	CoenzymeA binding site [chemical binding]; other site
85569003946	subunit interaction site [polypeptide binding]; other site
85569003947	PHB binding site; other site
85569003948	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
85569003949	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
85569003950	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
85569003951	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
85569003952	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
85569003953	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
85569003954	Walker A/P-loop; other site
85569003955	ATP binding site [chemical binding]; other site
85569003956	Q-loop/lid; other site
85569003957	ABC transporter signature motif; other site
85569003958	Walker B; other site
85569003959	D-loop; other site
85569003960	H-loop/switch region; other site
85569003961	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
85569003962	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
85569003963	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
85569003964	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
85569003965	catalytic residue [active]
85569003966	cysteine desufuration protein SufE; Provisional; Region: PRK09296
85569003967	L,D-transpeptidase; Provisional; Region: PRK10260
85569003968	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
85569003969	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
85569003970	murein lipoprotein; Provisional; Region: PRK15396
85569003971	murein lipoprotein; Provisional; Region: PRK15396
85569003972	pyruvate kinase; Provisional; Region: PRK09206
85569003973	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
85569003974	active site
85569003975	domain interfaces; other site
85569003976	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
85569003977	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
85569003978	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
85569003979	Putative lysophospholipase; Region: Hydrolase_4; cl19140
85569003980	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
85569003981	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
85569003982	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
85569003983	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
85569003984	substrate binding site [chemical binding]; other site
85569003985	dimer interface [polypeptide binding]; other site
85569003986	ATP binding site [chemical binding]; other site
85569003987	tetrathionate reductase subunit A; Provisional; Region: PRK14991
85569003988	The MopB_Tetrathionate-Ra CD contains tetrathionate reductase, subunit A, (TtrA) and other related proteins. The Salmonella enterica tetrathionate reductase catalyses the reduction of trithionate but not sulfur or thiosulfate. Members of this CD belong...; Region: MopB_Tetrathionate-Ra; cd02758
85569003989	putative [Fe4-S4] binding site [ion binding]; other site
85569003990	putative molybdopterin cofactor binding site [chemical binding]; other site
85569003991	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
85569003992	putative molybdopterin cofactor binding site; other site
85569003993	tetrathionate reductase subunit C; Provisional; Region: PRK14992
85569003994	tetrathionate reductase subunit B; Provisional; Region: PRK14993
85569003995	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
85569003996	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
85569003997	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
85569003998	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569003999	dimer interface [polypeptide binding]; other site
85569004000	phosphorylation site [posttranslational modification]
85569004001	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569004002	ATP binding site [chemical binding]; other site
85569004003	Mg2+ binding site [ion binding]; other site
85569004004	G-X-G motif; other site
85569004005	Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566
85569004006	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569004007	active site
85569004008	phosphorylation site [posttranslational modification]
85569004009	intermolecular recognition site; other site
85569004010	dimerization interface [polypeptide binding]; other site
85569004011	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569004012	DNA binding residues [nucleotide binding]
85569004013	dimerization interface [polypeptide binding]; other site
85569004014	hypothetical protein; Provisional; Region: PRK10292
85569004015	Uncharacterized conserved protein [Function unknown]; Region: COG1683
85569004016	Uncharacterized conserved protein [Function unknown]; Region: COG3272
85569004017	transcriptional regulator MirA; Provisional; Region: PRK15043
85569004018	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
85569004019	DNA binding residues [nucleotide binding]
85569004020	two component system sensor kinase SsrB; Provisional; Region: PRK15369
85569004021	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569004022	active site
85569004023	phosphorylation site [posttranslational modification]
85569004024	intermolecular recognition site; other site
85569004025	dimerization interface [polypeptide binding]; other site
85569004026	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569004027	DNA binding residues [nucleotide binding]
85569004028	dimerization interface [polypeptide binding]; other site
85569004029	two component system sensor kinase SsrA; Provisional; Region: PRK15347
85569004030	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569004031	dimerization interface [polypeptide binding]; other site
85569004032	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569004033	dimer interface [polypeptide binding]; other site
85569004034	phosphorylation site [posttranslational modification]
85569004035	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569004036	ATP binding site [chemical binding]; other site
85569004037	Mg2+ binding site [ion binding]; other site
85569004038	G-X-G motif; other site
85569004039	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569004040	active site
85569004041	phosphorylation site [posttranslational modification]
85569004042	intermolecular recognition site; other site
85569004043	dimerization interface [polypeptide binding]; other site
85569004044	pathogenicity island chaperone protein SpiC; Provisional; Region: PRK15368
85569004045	outer membrane secretin SsaC; Provisional; Region: PRK15346
85569004046	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
85569004047	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
85569004048	type III secretion system protein SsaD; Provisional; Region: PRK15367
85569004049	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
85569004050	type III secretion system chaperone SseA; Provisional; Region: PRK15365
85569004051	pathogenicity island 2 effector protein SseB; Provisional; Region: PRK15364
85569004052	pathogenicity island 2 chaperone protein SscA; Provisional; Region: PRK15363
85569004053	pathogenicity island 2 effector protein SseC; Provisional; Region: PRK15362
85569004054	Secretion system effector C (SseC) like family; Region: SseC; pfam04888
85569004055	pathogenicity island 2 effector protein SseD; Provisional; Region: PRK15361
85569004056	pathogenicity island 2 effector protein SseE; Provisional; Region: PRK15360
85569004057	type III secretion system chaperone protein SscB; Provisional; Region: PRK15359
85569004058	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
85569004059	TPR motif; other site
85569004060	binding surface
85569004061	pathogenicity island 2 effector protein SseF; Provisional; Region: PRK15358
85569004062	pathogenicity island 2 effector protein SseG; Provisional; Region: PRK15357
85569004063	type III secretion system needle protein SsaG; Provisional; Region: PRK15344
85569004064	type III secretion system protein SsaI; Provisional; Region: PRK15355
85569004065	type III secretion system lipoprotein SsaJ; Provisional; Region: PRK15348
85569004066	Type III secretion system subunit; Region: T3SS_LEE_assoc; pfam13327
85569004067	type III secretion system protein SsaK; Provisional; Region: PRK15354
85569004068	type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499
85569004069	type III secretion system protein SsaL; Provisional; Region: PRK15345
85569004070	HrpJ-like domain; Region: HrpJ; pfam07201
85569004071	TyeA; Region: TyeA; cl07611
85569004072	type III secretion system protein SsaM; Provisional; Region: PRK15353
85569004073	secretion system apparatus protein SsaV; Provisional; Region: PRK12720
85569004074	type III secretion system ATPase SsaN; Validated; Region: PRK07594
85569004075	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
85569004076	Walker A motif/ATP binding site; other site
85569004077	Walker B motif; other site
85569004078	type III secretion system protein SsaO; Provisional; Region: PRK15352
85569004079	type III secretion system protein SsaP; Provisional; Region: PRK15351
85569004080	type III secretion system protein SsaQ; Validated; Region: PRK08035
85569004081	Uncharacterized protein conserved in bacteria (DUF2057); Region: DUF2057; cl11437
85569004082	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
85569004083	Type III secretory pathway, component EscR [Intracellular trafficking and secretion]; Region: EscR; COG4790
85569004084	type III secretion system protein SsaS; Provisional; Region: PRK15350
85569004085	type III secretion system protein SsaT; Provisional; Region: PRK15349
85569004086	secretion system apparatus protein SsaU; Reviewed; Region: PRK12721
85569004087	multidrug efflux protein; Reviewed; Region: PRK01766
85569004088	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
85569004089	cation binding site [ion binding]; other site
85569004090	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
85569004091	Lumazine binding domain; Region: Lum_binding; pfam00677
85569004092	Lumazine binding domain; Region: Lum_binding; pfam00677
85569004093	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
85569004094	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569004095	S-adenosylmethionine binding site [chemical binding]; other site
85569004096	putative transporter; Provisional; Region: PRK11043
85569004097	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569004098	putative substrate translocation pore; other site
85569004099	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
85569004100	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569004101	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
85569004102	dimerization interface [polypeptide binding]; other site
85569004103	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
85569004104	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
85569004105	DNA binding site [nucleotide binding]
85569004106	domain linker motif; other site
85569004107	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
85569004108	dimerization interface [polypeptide binding]; other site
85569004109	ligand binding site [chemical binding]; other site
85569004110	superoxide dismutase; Provisional; Region: PRK10543
85569004111	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
85569004112	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
85569004113	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
85569004114	NlpC/P60 family; Region: NLPC_P60; pfam00877
85569004115	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
85569004116	putative GSH binding site [chemical binding]; other site
85569004117	catalytic residues [active]
85569004118	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
85569004119	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
85569004120	dimer interface [polypeptide binding]; other site
85569004121	catalytic site [active]
85569004122	putative active site [active]
85569004123	putative substrate binding site [chemical binding]; other site
85569004124	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
85569004125	dimer interface [polypeptide binding]; other site
85569004126	active site
85569004127	metal binding site [ion binding]; metal-binding site
85569004128	glutathione binding site [chemical binding]; other site
85569004129	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
85569004130	FMN binding site [chemical binding]; other site
85569004131	active site
85569004132	substrate binding site [chemical binding]; other site
85569004133	catalytic residue [active]
85569004134	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
85569004135	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
85569004136	Predicted Fe-S protein [General function prediction only]; Region: COG3313
85569004137	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
85569004138	active site
85569004139	catalytic tetrad [active]
85569004140	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
85569004141	E-class dimer interface [polypeptide binding]; other site
85569004142	P-class dimer interface [polypeptide binding]; other site
85569004143	active site
85569004144	Cu2+ binding site [ion binding]; other site
85569004145	Zn2+ binding site [ion binding]; other site
85569004146	Fusaric acid resistance protein family; Region: FUSC; pfam04632
85569004147	Fusaric acid resistance protein-like; Region: FUSC_2; cl19401
85569004148	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
85569004149	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
85569004150	HlyD family secretion protein; Region: HlyD_3; pfam13437
85569004151	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
85569004152	transcriptional regulator SlyA; Provisional; Region: PRK03573
85569004153	Transcriptional regulators [Transcription]; Region: MarR; COG1846
85569004154	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
85569004155	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
85569004156	lysozyme inhibitor; Provisional; Region: PRK11372
85569004157	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
85569004158	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
85569004159	Pyridoxine 5'-phosphate oxidase C-terminal dimerization region; Region: PNPOx_C; pfam10590
85569004160	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
85569004161	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
85569004162	active site
85569004163	HIGH motif; other site
85569004164	dimer interface [polypeptide binding]; other site
85569004165	KMSKS motif; other site
85569004166	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
85569004167	RNA binding surface [nucleotide binding]; other site
85569004168	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
85569004169	dimer interface [polypeptide binding]; other site
85569004170	pyridoxal binding site [chemical binding]; other site
85569004171	ATP binding site [chemical binding]; other site
85569004172	glutathionine S-transferase; Provisional; Region: PRK10542
85569004173	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
85569004174	C-terminal domain interface [polypeptide binding]; other site
85569004175	GSH binding site (G-site) [chemical binding]; other site
85569004176	dimer interface [polypeptide binding]; other site
85569004177	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
85569004178	dimer interface [polypeptide binding]; other site
85569004179	N-terminal domain interface [polypeptide binding]; other site
85569004180	substrate binding pocket (H-site) [chemical binding]; other site
85569004181	putative tripeptide transporter permease; Reviewed; Region: tppB; PRK09584
85569004182	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
85569004183	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569004184	putative substrate translocation pore; other site
85569004185	endonuclease III; Provisional; Region: PRK10702
85569004186	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
85569004187	minor groove reading motif; other site
85569004188	helix-hairpin-helix signature motif; other site
85569004189	substrate binding pocket [chemical binding]; other site
85569004190	active site
85569004191	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
85569004192	electron transport complex RsxE subunit; Provisional; Region: PRK12405
85569004193	electron transport complex protein RnfG; Validated; Region: PRK01908
85569004194	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
85569004195	electron transport complex protein RnfC; Provisional; Region: PRK05035
85569004196	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
85569004197	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
85569004198	SLBB domain; Region: SLBB; pfam10531
85569004199	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
85569004200	electron transport complex protein RnfB; Provisional; Region: PRK05113
85569004201	Putative Fe-S cluster; Region: FeS; cl17515
85569004202	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569004203	electron transport complex protein RsxA; Provisional; Region: PRK05151
85569004204	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
85569004205	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
85569004206	putative oxidoreductase; Provisional; Region: PRK11579
85569004207	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
85569004208	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
85569004209	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
85569004210	active site
85569004211	purine riboside binding site [chemical binding]; other site
85569004212	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
85569004213	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
85569004214	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
85569004215	fumarate hydratase; Provisional; Region: PRK15389
85569004216	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
85569004217	Fumarase C-terminus; Region: Fumerase_C; pfam05683
85569004218	fumarate hydratase; Reviewed; Region: fumC; PRK00485
85569004219	Class II fumarases; Region: Fumarase_classII; cd01362
85569004220	active site
85569004221	tetramer interface [polypeptide binding]; other site
85569004222	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
85569004223	sensor protein RstB; Provisional; Region: PRK10604
85569004224	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569004225	dimerization interface [polypeptide binding]; other site
85569004226	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569004227	dimer interface [polypeptide binding]; other site
85569004228	phosphorylation site [posttranslational modification]
85569004229	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569004230	ATP binding site [chemical binding]; other site
85569004231	Mg2+ binding site [ion binding]; other site
85569004232	G-X-G motif; other site
85569004233	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
85569004234	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
85569004235	active site
85569004236	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
85569004237	trimer interface [polypeptide binding]; other site
85569004238	eyelet of channel; other site
85569004239	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
85569004240	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569004241	active site
85569004242	phosphorylation site [posttranslational modification]
85569004243	intermolecular recognition site; other site
85569004244	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
85569004245	DNA binding site [nucleotide binding]
85569004246	GlpM protein; Region: GlpM; cl01212
85569004247	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
85569004248	Spore germination protein; Region: Spore_permease; cl17796
85569004249	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
85569004250	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
85569004251	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
85569004252	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
85569004253	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
85569004254	ligand binding site [chemical binding]; other site
85569004255	homodimer interface [polypeptide binding]; other site
85569004256	NAD(P) binding site [chemical binding]; other site
85569004257	trimer interface B [polypeptide binding]; other site
85569004258	trimer interface A [polypeptide binding]; other site
85569004259	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
85569004260	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
85569004261	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
85569004262	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
85569004263	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
85569004264	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
85569004265	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
85569004266	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569004267	putative substrate translocation pore; other site
85569004268	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
85569004269	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569004270	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
85569004271	dimerization interface [polypeptide binding]; other site
85569004272	substrate binding pocket [chemical binding]; other site
85569004273	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
85569004274	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
85569004275	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
85569004276	nucleotide binding site [chemical binding]; other site
85569004277	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
85569004278	putative dithiobiotin synthetase; Provisional; Region: PRK12374
85569004279	AAA domain; Region: AAA_26; pfam13500
85569004280	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
85569004281	Cl- selectivity filter; other site
85569004282	Cl- binding residues [ion binding]; other site
85569004283	pore gating glutamate residue; other site
85569004284	dimer interface [polypeptide binding]; other site
85569004285	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
85569004286	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569004287	Walker A/P-loop; other site
85569004288	ATP binding site [chemical binding]; other site
85569004289	Q-loop/lid; other site
85569004290	ABC transporter signature motif; other site
85569004291	Walker B; other site
85569004292	D-loop; other site
85569004293	H-loop/switch region; other site
85569004294	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc; cd04582
85569004295	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569004296	dimer interface [polypeptide binding]; other site
85569004297	conserved gate region; other site
85569004298	putative PBP binding loops; other site
85569004299	ABC-ATPase subunit interface; other site
85569004300	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
85569004301	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569004302	dimer interface [polypeptide binding]; other site
85569004303	conserved gate region; other site
85569004304	putative PBP binding loops; other site
85569004305	ABC-ATPase subunit interface; other site
85569004306	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
85569004307	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
85569004308	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
85569004309	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
85569004310	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
85569004311	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
85569004312	putative [Fe4-S4] binding site [ion binding]; other site
85569004313	putative molybdopterin cofactor binding site [chemical binding]; other site
85569004314	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
85569004315	putative molybdopterin cofactor binding site; other site
85569004316	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
85569004317	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
85569004318	putative [Fe4-S4] binding site [ion binding]; other site
85569004319	putative molybdopterin cofactor binding site [chemical binding]; other site
85569004320	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
85569004321	putative molybdopterin cofactor binding site; other site
85569004322	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
85569004323	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
85569004324	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
85569004325	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569004326	Coenzyme A binding pocket [chemical binding]; other site
85569004327	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
85569004328	hypothetical protein; Provisional; Region: PRK13659
85569004329	hypothetical protein; Provisional; Region: PRK02237
85569004330	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
85569004331	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
85569004332	putative active site pocket [active]
85569004333	putative metal binding site [ion binding]; other site
85569004334	putative oxidoreductase; Provisional; Region: PRK10083
85569004335	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
85569004336	putative NAD(P) binding site [chemical binding]; other site
85569004337	catalytic Zn binding site [ion binding]; other site
85569004338	structural Zn binding site [ion binding]; other site
85569004339	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569004340	putative substrate translocation pore; other site
85569004341	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
85569004342	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
85569004343	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
85569004344	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
85569004345	Transcriptional regulators [Transcription]; Region: GntR; COG1802
85569004346	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569004347	DNA-binding site [nucleotide binding]; DNA binding site
85569004348	FCD domain; Region: FCD; pfam07729
85569004349	malonic semialdehyde reductase; Provisional; Region: PRK10538
85569004350	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
85569004351	putative NAD(P) binding site [chemical binding]; other site
85569004352	homodimer interface [polypeptide binding]; other site
85569004353	homotetramer interface [polypeptide binding]; other site
85569004354	active site
85569004355	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
85569004356	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
85569004357	active site
85569004358	Zn binding site [ion binding]; other site
85569004359	General stress protein [General function prediction only]; Region: GsiB; COG3729
85569004360	hypothetical protein; Validated; Region: PRK03657
85569004361	hypothetical protein; Provisional; Region: PRK10053
85569004362	putative transporter; Provisional; Region: PRK10054
85569004363	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569004364	putative substrate translocation pore; other site
85569004365	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
85569004366	EamA-like transporter family; Region: EamA; pfam00892
85569004367	EamA-like transporter family; Region: EamA; pfam00892
85569004368	MarB protein; Region: MarB; pfam13999
85569004369	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
85569004370	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569004371	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569004372	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
85569004373	Transcriptional regulators [Transcription]; Region: MarR; COG1846
85569004374	inner membrane protein; Provisional; Region: PRK10995
85569004375	putative arabinose transporter; Provisional; Region: PRK03545
85569004376	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569004377	putative substrate translocation pore; other site
85569004378	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569004379	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569004380	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
85569004381	putative dimerization interface [polypeptide binding]; other site
85569004382	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
85569004383	NAD(P) binding site [chemical binding]; other site
85569004384	catalytic residues [active]
85569004385	glutaminase; Provisional; Region: PRK00971
85569004386	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
85569004387	Predicted membrane protein [Function unknown]; Region: COG3781
85569004388	Ketosteroid isomerase homolog [Function unknown]; Region: COG4319
85569004389	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
85569004390	eyelet of channel; other site
85569004391	trimer interface [polypeptide binding]; other site
85569004392	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
85569004393	Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Region: Complex1_49kDa; cl19174
85569004394	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
85569004395	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
85569004396	Rubredoxin [Energy production and conversion]; Region: COG1773
85569004397	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
85569004398	iron binding site [ion binding]; other site
85569004399	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
85569004400	HupF/HypC family; Region: HupF_HypC; cl00394
85569004401	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
85569004402	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
85569004403	putative substrate-binding site; other site
85569004404	nickel binding site [ion binding]; other site
85569004405	Ni,Fe-hydrogenase I cytochrome b subunit [Energy production and conversion]; Region: HyaC; COG1969
85569004406	hydrogenase 1 large subunit; Provisional; Region: PRK10170
85569004407	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
85569004408	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
85569004409	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
85569004410	NiFe/NiFeSe hydrogenase small subunit C-terminal; Region: NiFe_hyd_SSU_C; pfam14720
85569004411	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
85569004412	active site
85569004413	Transcriptional regulators [Transcription]; Region: FadR; COG2186
85569004414	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569004415	DNA-binding site [nucleotide binding]; DNA binding site
85569004416	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
85569004417	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
85569004418	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
85569004419	putative NAD(P) binding site [chemical binding]; other site
85569004420	catalytic Zn binding site [ion binding]; other site
85569004421	structural Zn binding site [ion binding]; other site
85569004422	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569004423	D-galactonate transporter; Region: 2A0114; TIGR00893
85569004424	putative substrate translocation pore; other site
85569004425	PhoPQ-activated pathogenicity-related protein [General function prediction only]; Region: PqaA; COG4287
85569004426	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569004427	Major Facilitator Superfamily; Region: MFS_1; pfam07690
85569004428	putative substrate translocation pore; other site
85569004429	hypothetical protein; Provisional; Region: PRK06184
85569004430	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569004431	CRISPR/Cas system-associated transcriptional regulator CasRa; Region: CasRa_I-A; cd09655
85569004432	Transcriptional regulators [Transcription]; Region: MarR; COG1846
85569004433	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
85569004434	putative DNA binding site [nucleotide binding]; other site
85569004435	putative Zn2+ binding site [ion binding]; other site
85569004436	S-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase) [Translation, ribosomal structure and biogenesis]; Region: QueA; COG0809
85569004437	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
85569004438	homotrimer interaction site [polypeptide binding]; other site
85569004439	putative active site [active]
85569004440	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
85569004441	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: StbD; COG2161
85569004442	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
85569004443	Winged helix-turn helix; Region: HTH_29; pfam13551
85569004444	Helix-turn-helix domain; Region: HTH_28; pfam13518
85569004445	Homeodomain-like domain; Region: HTH_32; pfam13565
85569004446	Transcriptional regulators [Transcription]; Region: PurR; COG1609
85569004447	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
85569004448	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
85569004449	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
85569004450	Na+/H+ antiporter family; Region: Na_H_antiporter; pfam03553
85569004451	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
85569004452	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
85569004453	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569004454	homodimer interface [polypeptide binding]; other site
85569004455	catalytic residue [active]
85569004456	glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100
85569004457	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
85569004458	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
85569004459	active site
85569004460	catalytic site [active]
85569004461	Maltooligosyl trehalose synthase [Carbohydrate transport and metabolism]; Region: TreY; COG3280
85569004462	Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336
85569004463	active site
85569004464	catalytic site [active]
85569004465	N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853
85569004466	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
85569004467	Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325
85569004468	catalytic site [active]
85569004469	active site
85569004470	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
85569004471	Protein of unknown function (DUF1264); Region: DUF1264; pfam06884
85569004472	acid-resistance protein; Provisional; Region: hdeB; PRK11566
85569004473	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
85569004474	biofilm-dependent modulation protein; Provisional; Region: PRK11436
85569004475	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
85569004476	malate dehydrogenase; Provisional; Region: PRK13529
85569004477	Malic enzyme, N-terminal domain; Region: malic; pfam00390
85569004478	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
85569004479	NAD(P) binding site [chemical binding]; other site
85569004480	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
85569004481	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
85569004482	NAD binding site [chemical binding]; other site
85569004483	substrate binding site [chemical binding]; other site
85569004484	catalytic Zn binding site [ion binding]; other site
85569004485	tetramer interface [polypeptide binding]; other site
85569004486	structural Zn binding site [ion binding]; other site
85569004487	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
85569004488	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
85569004489	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
85569004490	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
85569004491	aromatic amino acid exporter; Provisional; Region: PRK11689
85569004492	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
85569004493	trimer interface [polypeptide binding]; other site
85569004494	eyelet of channel; other site
85569004495	Uncharacterized conserved protein [Function unknown]; Region: COG3791
85569004496	methyl viologen resistance protein SmvA; Provisional; Region: PRK14995
85569004497	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569004498	putative substrate translocation pore; other site
85569004499	TetR family transcriptional regulator; Provisional; Region: PRK14996
85569004500	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
85569004501	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
85569004502	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
85569004503	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
85569004504	Respiratory nitrate reductase alpha N-terminal; Region: Nitr_red_alph_N; pfam14710
85569004505	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
85569004506	[4Fe-4S] binding site [ion binding]; other site
85569004507	molybdopterin cofactor binding site [chemical binding]; other site
85569004508	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
85569004509	molybdopterin cofactor binding site; other site
85569004510	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
85569004511	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
85569004512	Respiratory nitrate reductase beta C-terminal; Region: Nitr_red_bet_C; pfam14711
85569004513	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
85569004514	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
85569004515	hypothetical protein; Provisional; Region: PRK10281
85569004516	phenazine biosynthesis protein PhzF family; Region: PhzF_family; TIGR00654
85569004517	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
85569004518	L-asparagine permease; Provisional; Region: PRK15049
85569004519	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
85569004520	Uncharacterized conserved protein [Function unknown]; Region: COG3391
85569004521	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
85569004522	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
85569004523	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
85569004524	N-terminal plug; other site
85569004525	ligand-binding site [chemical binding]; other site
85569004526	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
85569004527	DNA-binding site [nucleotide binding]; DNA binding site
85569004528	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
85569004529	FCD domain; Region: FCD; pfam07729
85569004530	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
85569004531	Prostaglandin dehydrogenases; Region: PGDH; cd05288
85569004532	NAD(P) binding site [chemical binding]; other site
85569004533	substrate binding site [chemical binding]; other site
85569004534	dimer interface [polypeptide binding]; other site
85569004535	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
85569004536	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569004537	Coenzyme A binding pocket [chemical binding]; other site
85569004538	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
85569004539	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
85569004540	large tegument protein UL36; Provisional; Region: PHA03247
85569004541	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfB; COG4457
85569004542	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfC; COG4458
85569004543	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
85569004544	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
85569004545	tetrameric interface [polypeptide binding]; other site
85569004546	NAD binding site [chemical binding]; other site
85569004547	catalytic residues [active]
85569004548	substrate binding site [chemical binding]; other site
85569004549	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
85569004550	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569004551	DNA-binding site [nucleotide binding]; DNA binding site
85569004552	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
85569004553	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569004554	homodimer interface [polypeptide binding]; other site
85569004555	catalytic residue [active]
85569004556	D-alanyl-D-alanine dipeptidase [Cell envelope biogenesis, outer membrane]; Region: DdpX; COG2173
85569004557	secreted effector protein SifB; Provisional; Region: sifB; PRK09499
85569004558	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
85569004559	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
85569004560	Collagenase; Region: DUF3656; pfam12392
85569004561	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
85569004562	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569004563	non-specific DNA binding site [nucleotide binding]; other site
85569004564	salt bridge; other site
85569004565	sequence-specific DNA binding site [nucleotide binding]; other site
85569004566	Cupin domain; Region: Cupin_2; pfam07883
85569004567	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
85569004568	benzoate transporter; Region: benE; TIGR00843
85569004569	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
85569004570	tellurite resistance protein TehB; Provisional; Region: PRK11207
85569004571	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569004572	S-adenosylmethionine binding site [chemical binding]; other site
85569004573	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
85569004574	gating phenylalanine in ion channel; other site
85569004575	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
85569004576	putative trimer interface [polypeptide binding]; other site
85569004577	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
85569004578	putative trimer interface [polypeptide binding]; other site
85569004579	putative CoA binding site [chemical binding]; other site
85569004580	putative CoA binding site [chemical binding]; other site
85569004581	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
85569004582	putative trimer interface [polypeptide binding]; other site
85569004583	putative CoA binding site [chemical binding]; other site
85569004584	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
85569004585	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569004586	Coenzyme A binding pocket [chemical binding]; other site
85569004587	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
85569004588	oligomer interface [polypeptide binding]; other site
85569004589	active site
85569004590	metal binding site [ion binding]; metal-binding site
85569004591	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
85569004592	active site
85569004593	P-loop; other site
85569004594	phosphorylation site [posttranslational modification]
85569004595	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
85569004596	membrane complex biogenesis protein, BtpA family; Region: thylakoid_BtpA; TIGR00259
85569004597	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
85569004598	active site
85569004599	phosphorylation site [posttranslational modification]
85569004600	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
85569004601	substrate binding site [chemical binding]; other site
85569004602	hexamer interface [polypeptide binding]; other site
85569004603	metal binding site [ion binding]; metal-binding site
85569004604	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
85569004605	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
85569004606	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
85569004607	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
85569004608	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569004609	Coenzyme A binding pocket [chemical binding]; other site
85569004610	L-Lactate oxidase (LOX) FMN-binding domain. LOX is a member of the family of FMN-containing alpha-hydroxyacid oxidases and catalyzes the oxidation of l-lactate using molecular oxygen to generate pyruvate and H2O2.  This family occurs in both prokaryotes...; Region: LOX_like_FMN; cd04737
85569004611	teramer interface [polypeptide binding]; other site
85569004612	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
85569004613	active site
85569004614	FMN binding site [chemical binding]; other site
85569004615	catalytic residues [active]
85569004616	Uncharacterized conserved protein [Function unknown]; Region: COG2353
85569004617	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
85569004618	Carboxylesterase type B [Lipid metabolism]; Region: PnbA; COG2272
85569004619	substrate binding pocket [chemical binding]; other site
85569004620	catalytic triad [active]
85569004621	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
85569004622	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
85569004623	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569004624	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
85569004625	dimerization interface [polypeptide binding]; other site
85569004626	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
85569004627	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
85569004628	dimer interface [polypeptide binding]; other site
85569004629	ligand binding site [chemical binding]; other site
85569004630	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569004631	dimerization interface [polypeptide binding]; other site
85569004632	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
85569004633	dimer interface [polypeptide binding]; other site
85569004634	putative CheW interface [polypeptide binding]; other site
85569004635	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
85569004636	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
85569004637	substrate binding site [chemical binding]; other site
85569004638	catalytic Zn binding site [ion binding]; other site
85569004639	NAD binding site [chemical binding]; other site
85569004640	structural Zn binding site [ion binding]; other site
85569004641	dimer interface [polypeptide binding]; other site
85569004642	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
85569004643	putative metal binding site [ion binding]; other site
85569004644	putative homodimer interface [polypeptide binding]; other site
85569004645	putative homotetramer interface [polypeptide binding]; other site
85569004646	putative homodimer-homodimer interface [polypeptide binding]; other site
85569004647	putative allosteric switch controlling residues; other site
85569004648	Sif protein; Region: Sif; cl11505
85569004649	Phospholipase/lecithinase/hemolysin [Lipid metabolism / General function prediction only]; Region: COG3240
85569004650	Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846
85569004651	active site
85569004652	catalytic triad [active]
85569004653	oxyanion hole [active]
85569004654	Predicted membrane protein [Function unknown]; Region: COG3326
85569004655	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
85569004656	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
85569004657	substrate binding pocket [chemical binding]; other site
85569004658	membrane-bound complex binding site; other site
85569004659	hinge residues; other site
85569004660	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765
85569004661	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569004662	dimer interface [polypeptide binding]; other site
85569004663	conserved gate region; other site
85569004664	putative PBP binding loops; other site
85569004665	ABC-ATPase subunit interface; other site
85569004666	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
85569004667	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569004668	Walker A/P-loop; other site
85569004669	ATP binding site [chemical binding]; other site
85569004670	Q-loop/lid; other site
85569004671	ABC transporter signature motif; other site
85569004672	Walker B; other site
85569004673	D-loop; other site
85569004674	H-loop/switch region; other site
85569004675	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765
85569004676	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569004677	dimer interface [polypeptide binding]; other site
85569004678	conserved gate region; other site
85569004679	putative PBP binding loops; other site
85569004680	ABC-ATPase subunit interface; other site
85569004681	Predicted membrane protein [Function unknown]; Region: COG5305
85569004682	Methyltransferase domain; Region: Methyltransf_12; pfam08242
85569004683	cytochrome b561; Provisional; Region: PRK11513
85569004684	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
85569004685	putative active site [active]
85569004686	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
85569004687	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
85569004688	ATP binding site [chemical binding]; other site
85569004689	putative Mg++ binding site [ion binding]; other site
85569004690	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
85569004691	nucleotide binding region [chemical binding]; other site
85569004692	ATP-binding site [chemical binding]; other site
85569004693	Helicase associated domain (HA2); Region: HA2; pfam04408
85569004694	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
85569004695	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
85569004696	azoreductase; Reviewed; Region: PRK00170
85569004697	Uncharacterized conserved protein [Function unknown]; Region: COG3791
85569004698	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
85569004699	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
85569004700	hypothetical protein; Provisional; Region: PRK10695
85569004701	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
85569004702	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
85569004703	putative ligand binding site [chemical binding]; other site
85569004704	putative NAD binding site [chemical binding]; other site
85569004705	catalytic site [active]
85569004706	heat-inducible protein; Provisional; Region: PRK10449
85569004707	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
85569004708	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
85569004709	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
85569004710	dimer interface [polypeptide binding]; other site
85569004711	PYR/PP interface [polypeptide binding]; other site
85569004712	TPP binding site [chemical binding]; other site
85569004713	substrate binding site [chemical binding]; other site
85569004714	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
85569004715	Domain of unknown function; Region: EKR; pfam10371
85569004716	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
85569004717	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
85569004718	TPP-binding site [chemical binding]; other site
85569004719	dimer interface [polypeptide binding]; other site
85569004720	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
85569004721	Ligand Binding Site [chemical binding]; other site
85569004722	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
85569004723	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
85569004724	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
85569004725	Ligand Binding Site [chemical binding]; other site
85569004726	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
85569004727	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
85569004728	ATP binding site [chemical binding]; other site
85569004729	Mg++ binding site [ion binding]; other site
85569004730	motif III; other site
85569004731	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
85569004732	nucleotide binding region [chemical binding]; other site
85569004733	ATP-binding site [chemical binding]; other site
85569004734	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
85569004735	putative RNA binding site [nucleotide binding]; other site
85569004736	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
85569004737	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
85569004738	Cl binding site [ion binding]; other site
85569004739	oligomer interface [polypeptide binding]; other site
85569004740	HAMP domain; Region: HAMP; pfam00672
85569004741	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
85569004742	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cl19050
85569004743	dimer interface [polypeptide binding]; other site
85569004744	putative CheW interface [polypeptide binding]; other site
85569004745	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
85569004746	Smr domain; Region: Smr; pfam01713
85569004747	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
85569004748	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
85569004749	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
85569004750	DNA binding site [nucleotide binding]
85569004751	active site
85569004752	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
85569004753	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
85569004754	ligand binding site [chemical binding]; other site
85569004755	flexible hinge region; other site
85569004756	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
85569004757	putative switch regulator; other site
85569004758	non-specific DNA interactions [nucleotide binding]; other site
85569004759	DNA binding site [nucleotide binding]
85569004760	sequence specific DNA binding site [nucleotide binding]; other site
85569004761	putative cAMP binding site [chemical binding]; other site
85569004762	universal stress protein UspE; Provisional; Region: PRK11175
85569004763	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
85569004764	Ligand Binding Site [chemical binding]; other site
85569004765	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
85569004766	Ligand Binding Site [chemical binding]; other site
85569004767	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
85569004768	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
85569004769	Mechanosensitive ion channel; Region: MS_channel; pfam00924
85569004770	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
85569004771	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569004772	non-specific DNA binding site [nucleotide binding]; other site
85569004773	salt bridge; other site
85569004774	sequence-specific DNA binding site [nucleotide binding]; other site
85569004775	Cupin domain; Region: Cupin_2; pfam07883
85569004776	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
85569004777	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: Tpx; COG2077
85569004778	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
85569004779	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
85569004780	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569004781	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
85569004782	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
85569004783	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
85569004784	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
85569004785	oxidoreductase; Provisional; Region: PRK12742
85569004786	classical (c) SDRs; Region: SDR_c; cd05233
85569004787	NAD(P) binding site [chemical binding]; other site
85569004788	active site
85569004789	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
85569004790	active site
85569004791	catalytic tetrad [active]
85569004792	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569004793	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569004794	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
85569004795	putative effector binding pocket; other site
85569004796	putative dimerization interface [polypeptide binding]; other site
85569004797	phenylcoumaran benzylic ether reductase (PCBER) like, atypical (a) SDRs; Region: PCBER_SDR_a; cd05259
85569004798	NAD(P) binding site [chemical binding]; other site
85569004799	active site lysine
85569004800	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
85569004801	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
85569004802	peptide binding site [polypeptide binding]; other site
85569004803	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
85569004804	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
85569004805	putative active site [active]
85569004806	Zn binding site [ion binding]; other site
85569004807	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
85569004808	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
85569004809	active site
85569004810	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
85569004811	dimer interface [polypeptide binding]; other site
85569004812	catalytic triad [active]
85569004813	peroxidatic and resolving cysteines [active]
85569004814	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
85569004815	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
85569004816	putative aromatic amino acid binding site; other site
85569004817	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
85569004818	putative active site [active]
85569004819	heme pocket [chemical binding]; other site
85569004820	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569004821	Walker A motif; other site
85569004822	ATP binding site [chemical binding]; other site
85569004823	Walker B motif; other site
85569004824	arginine finger; other site
85569004825	hypothetical protein; Provisional; Region: PRK05415
85569004826	Predicted membrane protein [Function unknown]; Region: COG3768
85569004827	Predicted ATPase [General function prediction only]; Region: COG3106
85569004828	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
85569004829	active site residue [active]
85569004830	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
85569004831	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
85569004832	phage shock protein C; Region: phageshock_pspC; TIGR02978
85569004833	phage shock protein B; Provisional; Region: pspB; PRK09458
85569004834	phage shock protein PspA; Provisional; Region: PRK10698
85569004835	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
85569004836	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
85569004837	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569004838	Walker A motif; other site
85569004839	ATP binding site [chemical binding]; other site
85569004840	Walker B motif; other site
85569004841	arginine finger; other site
85569004842	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
85569004843	antimicrobial peptide ABC transporter periplasmic binding protein SapA; Provisional; Region: PRK15109
85569004844	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
85569004845	peptide binding site [polypeptide binding]; other site
85569004846	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569004847	dimer interface [polypeptide binding]; other site
85569004848	conserved gate region; other site
85569004849	putative PBP binding loops; other site
85569004850	ABC-ATPase subunit interface; other site
85569004851	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
85569004852	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
85569004853	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569004854	dimer interface [polypeptide binding]; other site
85569004855	conserved gate region; other site
85569004856	putative PBP binding loops; other site
85569004857	ABC-ATPase subunit interface; other site
85569004858	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
85569004859	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
85569004860	Walker A/P-loop; other site
85569004861	ATP binding site [chemical binding]; other site
85569004862	Q-loop/lid; other site
85569004863	ABC transporter signature motif; other site
85569004864	Walker B; other site
85569004865	D-loop; other site
85569004866	H-loop/switch region; other site
85569004867	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
85569004868	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
85569004869	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
85569004870	Walker A/P-loop; other site
85569004871	ATP binding site [chemical binding]; other site
85569004872	Q-loop/lid; other site
85569004873	ABC transporter signature motif; other site
85569004874	Walker B; other site
85569004875	D-loop; other site
85569004876	H-loop/switch region; other site
85569004877	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
85569004878	Protein kinase domain; Region: Pkinase; pfam00069
85569004879	Enoyl-[acyl-carrier-protein]; Region: FabI; COG0623
85569004880	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
85569004881	NAD binding site [chemical binding]; other site
85569004882	homotetramer interface [polypeptide binding]; other site
85569004883	homodimer interface [polypeptide binding]; other site
85569004884	substrate binding site [chemical binding]; other site
85569004885	active site
85569004886	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
85569004887	Uncharacterized conserved protein [Function unknown]; Region: COG2128
85569004888	Uncharacterized conserved protein [Function unknown]; Region: COG2128
85569004889	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
85569004890	exoribonuclease II; Provisional; Region: PRK05054
85569004891	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
85569004892	RNB domain; Region: RNB; pfam00773
85569004893	S1 RNA binding domain; Region: S1; pfam00575
85569004894	RNase II stability modulator; Provisional; Region: PRK10060
85569004895	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
85569004896	putative active site [active]
85569004897	heme pocket [chemical binding]; other site
85569004898	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
85569004899	metal binding site [ion binding]; metal-binding site
85569004900	active site
85569004901	I-site; other site
85569004902	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
85569004903	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
85569004904	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
85569004905	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
85569004906	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
85569004907	putative rRNA binding site [nucleotide binding]; other site
85569004908	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
85569004909	active site
85569004910	dimer interface [polypeptide binding]; other site
85569004911	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
85569004912	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
85569004913	TPR motif; other site
85569004914	binding surface
85569004915	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
85569004916	binding surface
85569004917	TPR motif; other site
85569004918	Predicted membrane protein [Function unknown]; Region: COG3771
85569004919	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
85569004920	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
85569004921	active site
85569004922	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
85569004923	dimerization interface [polypeptide binding]; other site
85569004924	active site
85569004925	aconitate hydratase; Validated; Region: PRK09277
85569004926	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
85569004927	substrate binding site [chemical binding]; other site
85569004928	ligand binding site [chemical binding]; other site
85569004929	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
85569004930	substrate binding site [chemical binding]; other site
85569004931	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
85569004932	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569004933	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
85569004934	substrate binding site [chemical binding]; other site
85569004935	putative dimerization interface [polypeptide binding]; other site
85569004936	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
85569004937	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
85569004938	active site
85569004939	interdomain interaction site; other site
85569004940	putative metal-binding site [ion binding]; other site
85569004941	nucleotide binding site [chemical binding]; other site
85569004942	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
85569004943	domain I; other site
85569004944	DNA binding groove [nucleotide binding]
85569004945	phosphate binding site [ion binding]; other site
85569004946	domain II; other site
85569004947	domain III; other site
85569004948	nucleotide binding site [chemical binding]; other site
85569004949	catalytic site [active]
85569004950	domain IV; other site
85569004951	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
85569004952	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
85569004953	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
85569004954	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
85569004955	hypothetical protein; Provisional; Region: PRK11037
85569004956	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
85569004957	putative inner membrane peptidase; Provisional; Region: PRK11778
85569004958	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
85569004959	tandem repeat interface [polypeptide binding]; other site
85569004960	oligomer interface [polypeptide binding]; other site
85569004961	active site residues [active]
85569004962	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
85569004963	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
85569004964	NADP binding site [chemical binding]; other site
85569004965	homodimer interface [polypeptide binding]; other site
85569004966	active site
85569004967	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
85569004968	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
85569004969	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
85569004970	homodimer interface [polypeptide binding]; other site
85569004971	Walker A motif; other site
85569004972	ATP binding site [chemical binding]; other site
85569004973	hydroxycobalamin binding site [chemical binding]; other site
85569004974	Walker B motif; other site
85569004975	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
85569004976	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
85569004977	RNA binding surface [nucleotide binding]; other site
85569004978	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
85569004979	probable active site [active]
85569004980	hypothetical protein; Provisional; Region: PRK11630
85569004981	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
85569004982	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
85569004983	active site
85569004984	anthranilate synthase component I; Provisional; Region: PRK13564
85569004985	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
85569004986	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
85569004987	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
85569004988	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
85569004989	glutamine binding [chemical binding]; other site
85569004990	catalytic triad [active]
85569004991	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
85569004992	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
85569004993	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
85569004994	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
85569004995	active site
85569004996	ribulose/triose binding site [chemical binding]; other site
85569004997	phosphate binding site [ion binding]; other site
85569004998	substrate (anthranilate) binding pocket [chemical binding]; other site
85569004999	product (indole) binding pocket [chemical binding]; other site
85569005000	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
85569005001	active site
85569005002	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
85569005003	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569005004	catalytic residue [active]
85569005005	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
85569005006	substrate binding site [chemical binding]; other site
85569005007	active site
85569005008	catalytic residues [active]
85569005009	heterodimer interface [polypeptide binding]; other site
85569005010	General stress protein [General function prediction only]; Region: GsiB; COG3729
85569005011	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
85569005012	dimerization interface [polypeptide binding]; other site
85569005013	metal binding site [ion binding]; metal-binding site
85569005014	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
85569005015	dinuclear metal binding motif [ion binding]; other site
85569005016	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
85569005017	dimanganese center [ion binding]; other site
85569005018	outer membrane protein W; Provisional; Region: PRK10959
85569005019	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
85569005020	hypothetical protein; Provisional; Region: PRK02868
85569005021	intracellular septation protein A; Reviewed; Region: PRK00259
85569005022	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
85569005023	transport protein TonB; Provisional; Region: PRK10819
85569005024	Gram-negative bacterial TonB protein C-terminal; Region: TonB_C; pfam03544
85569005025	YciI-like protein; Reviewed; Region: PRK11370
85569005026	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
85569005027	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
85569005028	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
85569005029	putative active site [active]
85569005030	catalytic site [active]
85569005031	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
85569005032	putative active site [active]
85569005033	catalytic site [active]
85569005034	dsDNA-mimic protein; Reviewed; Region: PRK05094
85569005035	Ion transport protein; Region: Ion_trans; pfam00520
85569005036	Ion channel; Region: Ion_trans_2; pfam07885
85569005037	Double zinc ribbon; Region: DZR; pfam12773
85569005038	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
85569005039	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
85569005040	Walker A/P-loop; other site
85569005041	ATP binding site [chemical binding]; other site
85569005042	Q-loop/lid; other site
85569005043	ABC transporter signature motif; other site
85569005044	Walker B; other site
85569005045	D-loop; other site
85569005046	H-loop/switch region; other site
85569005047	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
85569005048	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
85569005049	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
85569005050	Walker A/P-loop; other site
85569005051	ATP binding site [chemical binding]; other site
85569005052	Q-loop/lid; other site
85569005053	ABC transporter signature motif; other site
85569005054	Walker B; other site
85569005055	D-loop; other site
85569005056	H-loop/switch region; other site
85569005057	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
85569005058	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
85569005059	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
85569005060	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569005061	dimer interface [polypeptide binding]; other site
85569005062	conserved gate region; other site
85569005063	putative PBP binding loops; other site
85569005064	ABC-ATPase subunit interface; other site
85569005065	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
85569005066	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569005067	dimer interface [polypeptide binding]; other site
85569005068	conserved gate region; other site
85569005069	putative PBP binding loops; other site
85569005070	ABC-ATPase subunit interface; other site
85569005071	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
85569005072	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
85569005073	peptide binding site [polypeptide binding]; other site
85569005074	hypothetical protein; Provisional; Region: PRK11111
85569005075	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
85569005076	Coenzyme A acylating aldehyde dehydrogenase (ACDH), Ethanolamine utilization protein EutE, and related proteins; Region: ALDH_F20_ACDH_EutE-like; cd07081
85569005077	putative catalytic cysteine [active]
85569005078	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
85569005079	putative active site [active]
85569005080	metal binding site [ion binding]; metal-binding site
85569005081	thymidine kinase; Provisional; Region: PRK04296
85569005082	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
85569005083	DNA-binding protein H-NS [General function prediction only]; Region: Hns; COG2916
85569005084	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
85569005085	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
85569005086	active site
85569005087	tetramer interface; other site
85569005088	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569005089	active site
85569005090	response regulator of RpoS; Provisional; Region: PRK10693
85569005091	phosphorylation site [posttranslational modification]
85569005092	intermolecular recognition site; other site
85569005093	dimerization interface [polypeptide binding]; other site
85569005094	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
85569005095	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
85569005096	active site
85569005097	nucleophile elbow; other site
85569005098	hypothetical protein; Provisional; Region: PRK01617
85569005099	SEC-C motif; Region: SEC-C; cl19389
85569005100	SEC-C motif; Region: SEC-C; cl19389
85569005101	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
85569005102	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
85569005103	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
85569005104	putative active site [active]
85569005105	putative substrate binding site [chemical binding]; other site
85569005106	putative cosubstrate binding site; other site
85569005107	catalytic site [active]
85569005108	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
85569005109	Sel1-like repeats; Region: SEL1; smart00671
85569005110	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
85569005111	Sel1-like repeats; Region: SEL1; smart00671
85569005112	Sel1-like repeats; Region: SEL1; smart00671
85569005113	Sel1-like repeats; Region: SEL1; smart00671
85569005114	Sel1-like repeats; Region: SEL1; smart00671
85569005115	Sel1-like repeats; Region: SEL1; smart00671
85569005116	Sel1-like repeats; Region: SEL1; smart00671
85569005117	Sel1-like repeats; Region: SEL1; smart00671
85569005118	Sel1-like repeats; Region: SEL1; smart00671
85569005119	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
85569005120	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
85569005121	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
85569005122	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
85569005123	Respiratory nitrate reductase beta C-terminal; Region: Nitr_red_bet_C; pfam14711
85569005124	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
85569005125	Respiratory nitrate reductase alpha N-terminal; Region: Nitr_red_alph_N; pfam14710
85569005126	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
85569005127	[4Fe-4S] binding site [ion binding]; other site
85569005128	molybdopterin cofactor binding site [chemical binding]; other site
85569005129	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
85569005130	molybdopterin cofactor binding site; other site
85569005131	lysophospholipid transporter LplT; Provisional; Region: PRK11195; cl19150
85569005132	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
85569005133	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
85569005134	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
85569005135	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569005136	dimerization interface [polypeptide binding]; other site
85569005137	Histidine kinase; Region: HisKA_3; pfam07730
85569005138	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569005139	ATP binding site [chemical binding]; other site
85569005140	Mg2+ binding site [ion binding]; other site
85569005141	G-X-G motif; other site
85569005142	transcriptional regulator NarL; Provisional; Region: PRK10651
85569005143	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569005144	active site
85569005145	phosphorylation site [posttranslational modification]
85569005146	intermolecular recognition site; other site
85569005147	dimerization interface [polypeptide binding]; other site
85569005148	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569005149	DNA binding residues [nucleotide binding]
85569005150	dimerization interface [polypeptide binding]; other site
85569005151	putative invasin; Provisional; Region: PRK10177
85569005152	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
85569005153	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
85569005154	cation transport regulator; Reviewed; Region: chaB; PRK09582
85569005155	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
85569005156	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
85569005157	Transposase IS200 like; Region: Y1_Tnp; pfam01797
85569005158	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
85569005159	hypothetical protein; Provisional; Region: PRK10941
85569005160	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
85569005161	hypothetical protein; Provisional; Region: PRK10278
85569005162	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
85569005163	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569005164	S-adenosylmethionine binding site [chemical binding]; other site
85569005165	peptide chain release factor 1; Validated; Region: prfA; PRK00591
85569005166	This domain is found in peptide chain release factors; Region: PCRF; smart00937
85569005167	RF-1 domain; Region: RF-1; pfam00472
85569005168	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
85569005169	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
85569005170	tRNA; other site
85569005171	putative tRNA binding site [nucleotide binding]; other site
85569005172	putative NADP binding site [chemical binding]; other site
85569005173	Glutamyl-tRNAGlu reductase, dimerization domain; Region: GlutR_dimer; pfam00745
85569005174	Outer membrane lipoprotein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: LolB; COG3017
85569005175	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
85569005176	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
85569005177	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
85569005178	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
85569005179	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
85569005180	active site
85569005181	putative transporter; Provisional; Region: PRK11660
85569005182	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
85569005183	Sulfate transporter family; Region: Sulfate_transp; pfam00916
85569005184	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
85569005185	hypothetical protein; Provisional; Region: PRK10692
85569005186	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
85569005187	putative active site [active]
85569005188	catalytic residue [active]
85569005189	GTP-binding protein YchF; Reviewed; Region: PRK09601
85569005190	YchF GTPase; Region: YchF; cd01900
85569005191	G1 box; other site
85569005192	GTP/Mg2+ binding site [chemical binding]; other site
85569005193	Switch I region; other site
85569005194	G2 box; other site
85569005195	Switch II region; other site
85569005196	G3 box; other site
85569005197	G4 box; other site
85569005198	G5 box; other site
85569005199	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
85569005200	Protein of unknown function (DUF2743); Region: DUF2743; pfam10899
85569005201	Protein of unknown function (DUF4427); Region: DUF4427; pfam14468
85569005202	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
85569005203	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
85569005204	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
85569005205	NiFe/NiFeSe hydrogenase small subunit C-terminal; Region: NiFe_hyd_SSU_C; pfam14720
85569005206	hydrogenase 1 large subunit; Provisional; Region: PRK10170
85569005207	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
85569005208	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
85569005209	putative substrate-binding site; other site
85569005210	nickel binding site [ion binding]; other site
85569005211	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
85569005212	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
85569005213	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
85569005214	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
85569005215	hypothetical protein; Provisional; Region: PRK14749
85569005216	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
85569005217	Glu/Leu/Phe/Val dehydrogenase, dimerization domain; Region: ELFV_dehydrog_N; pfam02812
85569005218	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
85569005219	NAD(P) binding site [chemical binding]; other site
85569005220	trehalase; Provisional; Region: treA; PRK13271
85569005221	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
85569005222	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
85569005223	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
85569005224	Flagellar regulator YcgR; Region: YcgR; pfam07317
85569005225	PilZ domain; Region: PilZ; pfam07238
85569005226	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
85569005227	N-acetyl-D-glucosamine binding site [chemical binding]; other site
85569005228	catalytic residue [active]
85569005229	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
85569005230	dimer interface [polypeptide binding]; other site
85569005231	catalytic triad [active]
85569005232	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
85569005233	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
85569005234	TrkA-C domain; Region: TrkA_C; pfam02080
85569005235	Transporter associated domain; Region: CorC_HlyC; smart01091
85569005236	alanine racemase; Reviewed; Region: dadX; PRK03646
85569005237	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
85569005238	active site
85569005239	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
85569005240	substrate binding site [chemical binding]; other site
85569005241	catalytic residues [active]
85569005242	dimer interface [polypeptide binding]; other site
85569005243	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
85569005244	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569005245	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569005246	SpoVR family protein; Provisional; Region: PRK11767
85569005247	fatty acid metabolism regulator; Provisional; Region: PRK04984
85569005248	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569005249	DNA-binding site [nucleotide binding]; DNA binding site
85569005250	FadR C-terminal domain; Region: FadR_C; pfam07840
85569005251	sodium/proton antiporter; Reviewed; Region: nhaB; PRK09547
85569005252	disulfide bond formation protein B; Provisional; Region: PRK01749
85569005253	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
85569005254	GnsA/GnsB family; Region: GnsAB; pfam08178
85569005255	autotransport protein MisL; Provisional; Region: PRK15313
85569005256	hypothetical protein; Provisional; Region: PRK05170
85569005257	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
85569005258	hypothetical protein; Provisional; Region: PRK10691
85569005259	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
85569005260	septum formation inhibitor; Reviewed; Region: minC; PRK03511
85569005261	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
85569005262	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
85569005263	cell division inhibitor MinD; Provisional; Region: PRK10818
85569005264	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
85569005265	P-loop; other site
85569005266	ADP binding residues [chemical binding]; other site
85569005267	Switch I; other site
85569005268	Switch II; other site
85569005269	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
85569005270	ribonuclease D; Provisional; Region: PRK10829
85569005271	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
85569005272	catalytic site [active]
85569005273	putative active site [active]
85569005274	putative substrate binding site [chemical binding]; other site
85569005275	HRDC domain; Region: HRDC; cl02578
85569005276	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
85569005277	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
85569005278	acyl-activating enzyme (AAE) consensus motif; other site
85569005279	putative AMP binding site [chemical binding]; other site
85569005280	putative active site [active]
85569005281	putative CoA binding site [chemical binding]; other site
85569005282	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
85569005283	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
85569005284	Glycoprotease family; Region: Peptidase_M22; pfam00814
85569005285	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
85569005286	CRISPR/Cas system-associated DinG family helicase Csf4; Region: Csf4_U; cd09708
85569005287	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
85569005288	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
85569005289	homotrimer interaction site [polypeptide binding]; other site
85569005290	putative active site [active]
85569005291	hypothetical protein; Provisional; Region: PRK05114
85569005292	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
85569005293	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
85569005294	chorismate binding enzyme; Region: Chorismate_bind; cl10555
85569005295	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
85569005296	putative active site [active]
85569005297	putative CoA binding site [chemical binding]; other site
85569005298	nudix motif; other site
85569005299	metal binding site [ion binding]; metal-binding site
85569005300	L-serine deaminase; Provisional; Region: PRK15023
85569005301	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
85569005302	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
85569005303	phage resistance protein; Provisional; Region: PRK10551
85569005304	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
85569005305	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
85569005306	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
85569005307	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
85569005308	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
85569005309	Transporter associated domain; Region: CorC_HlyC; smart01091
85569005310	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
85569005311	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
85569005312	active pocket/dimerization site; other site
85569005313	active site
85569005314	phosphorylation site [posttranslational modification]
85569005315	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
85569005316	active site
85569005317	phosphorylation site [posttranslational modification]
85569005318	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
85569005319	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
85569005320	hypothetical protein; Provisional; Region: PRK02913
85569005321	hypothetical protein; Provisional; Region: PRK11469
85569005322	Domain of unknown function DUF; Region: DUF204; pfam02659
85569005323	Domain of unknown function DUF; Region: DUF204; pfam02659
85569005324	Methyltransferase domain; Region: Methyltransf_31; pfam13847
85569005325	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569005326	S-adenosylmethionine binding site [chemical binding]; other site
85569005327	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
85569005328	Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717
85569005329	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
85569005330	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
85569005331	DNA-binding site [nucleotide binding]; DNA binding site
85569005332	RNA-binding motif; other site
85569005333	YobH-like protein; Region: YobH; pfam13996
85569005334	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
85569005335	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
85569005336	dimerization interface [polypeptide binding]; other site
85569005337	putative Zn2+ binding site [ion binding]; other site
85569005338	putative DNA binding site [nucleotide binding]; other site
85569005339	Bacterial transcriptional regulator; Region: IclR; pfam01614
85569005340	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569005341	Major Facilitator Superfamily; Region: MFS_1; pfam07690
85569005342	putative substrate translocation pore; other site
85569005343	heat shock protein HtpX; Provisional; Region: PRK05457
85569005344	carboxy-terminal protease; Provisional; Region: PRK11186
85569005345	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
85569005346	protein binding site [polypeptide binding]; other site
85569005347	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
85569005348	Catalytic dyad [active]
85569005349	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
85569005350	ProP expression regulator; Provisional; Region: PRK04950
85569005351	putative RNA binding sites [nucleotide binding]; other site
85569005352	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
85569005353	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
85569005354	Paraquat-inducible protein A; Region: PqiA; pfam04403
85569005355	Paraquat-inducible protein A; Region: PqiA; pfam04403
85569005356	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
85569005357	mce related protein; Region: MCE; pfam02470
85569005358	mce related protein; Region: MCE; pfam02470
85569005359	mce related protein; Region: MCE; pfam02470
85569005360	mce related protein; Region: MCE; pfam02470
85569005361	mce related protein; Region: MCE; pfam02470
85569005362	mce related protein; Region: MCE; pfam02470
85569005363	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
85569005364	Methyltransferase domain; Region: Methyltransf_26; pfam13659
85569005365	Uncharacterized conserved protein [Function unknown]; Region: COG3270
85569005366	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
85569005367	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
85569005368	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
85569005369	type III secretion protein SopE2; Provisional; Region: PRK15280
85569005370	Salmonella type III secretion SopE effector N-terminus; Region: SecIII_SopE_N; pfam05364
85569005371	SopE GEF domain; Region: SopE_GEF; pfam07487
85569005372	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
85569005373	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569005374	Coenzyme A binding pocket [chemical binding]; other site
85569005375	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
85569005376	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
85569005377	DNA binding site [nucleotide binding]
85569005378	active site
85569005379	Int/Topo IB signature motif; other site
85569005380	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
85569005381	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
85569005382	EamA-like transporter family; Region: EamA; pfam00892
85569005383	EamA-like transporter family; Region: EamA; pfam00892
85569005384	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
85569005385	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
85569005386	DNA-binding interface [nucleotide binding]; DNA binding site
85569005387	Phage-encoded virulence factor; Region: PAGK; pfam15284
85569005388	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cl00019
85569005389	ADP-ribose binding site [chemical binding]; other site
85569005390	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
85569005391	Protein of unknown function (DUF1441); Region: DUF1441; pfam07278
85569005392	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
85569005393	Predicted chitinase [General function prediction only]; Region: COG3179
85569005394	exonuclease VIII; Reviewed; Region: PRK09709
85569005395	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
85569005396	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
85569005397	dimer interface [polypeptide binding]; other site
85569005398	active site
85569005399	Int/Topo IB signature motif; other site
85569005400	lipopolysaccharide 1,2-N-acetylglucosaminetransferase; Provisional; Region: PRK15484
85569005401	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
85569005402	Methyltransferase domain; Region: Methyltransf_12; pfam08242
85569005403	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
85569005404	Phage Tail Collar Domain; Region: Collar; pfam07484
85569005405	Protein of unknown function (DUF2612); Region: DUF2612; pfam11041
85569005406	Baseplate J-like protein; Region: Baseplate_J; cl01294
85569005407	Phage-related baseplate assembly protein; Region: Phage_base_V; cl17812
85569005408	Predicted solute binding protein [General function prediction only]; Region: COG3889
85569005409	Tim44-like domain; Region: Tim44; cl09208
85569005410	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
85569005411	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
85569005412	N-acetyl-D-glucosamine binding site [chemical binding]; other site
85569005413	catalytic residue [active]
85569005414	Protein of unknown function (DUF3383); Region: DUF3383; pfam11863
85569005415	Uncharacterized protein conserved in bacteria (DUF2213); Region: DUF2213; pfam09979
85569005416	Uncharacterized protein, homolog of phage Mu protein gp30 [Function unknown]; Region: COG2369
85569005417	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
85569005418	Protein of unknown function (DUF1073); Region: DUF1073; pfam06381
85569005419	phage-related protein, HI1409 family; Region: phge_rel_HI1409; TIGR01555
85569005420	Phage terminase large subunit; Region: Terminase_3; cl12054
85569005421	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
85569005422	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
85569005423	catalytic residues [active]
85569005424	Transposase IS200 like; Region: Y1_Tnp; pfam01797
85569005425	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
85569005426	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
85569005427	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
85569005428	Replication protein P; Region: Phage_lambda_P; pfam06992
85569005429	Protein of unknown function (DUF1376); Region: DUF1376; cl01531
85569005430	primosomal protein DnaI; Provisional; Region: PRK02854
85569005431	transcriptional repressor DicA; Reviewed; Region: PRK09706
85569005432	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569005433	non-specific DNA binding site [nucleotide binding]; other site
85569005434	salt bridge; other site
85569005435	sequence-specific DNA binding site [nucleotide binding]; other site
85569005436	exonuclease VIII; Reviewed; Region: PRK09709
85569005437	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
85569005438	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
85569005439	recombination and repair protein RecT; Reviewed; Region: recT; PRK09846
85569005440	Excisionase-like protein; Region: Exc; pfam07825
85569005441	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
85569005442	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
85569005443	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
85569005444	dimer interface [polypeptide binding]; other site
85569005445	active site
85569005446	Int/Topo IB signature motif; other site
85569005447	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
85569005448	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
85569005449	hypothetical protein; Provisional; Region: PRK10301
85569005450	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
85569005451	Predicted amidohydrolase [General function prediction only]; Region: COG0388
85569005452	exodeoxyribonuclease X; Provisional; Region: PRK07983
85569005453	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
85569005454	active site
85569005455	catalytic site [active]
85569005456	substrate binding site [chemical binding]; other site
85569005457	protease 2; Provisional; Region: PRK10115
85569005458	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
85569005459	Protein of unknown function (DUF533); Region: DUF533; pfam04391
85569005460	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
85569005461	putative metal binding site [ion binding]; other site
85569005462	hypothetical protein; Provisional; Region: PRK13680
85569005463	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
85569005464	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
85569005465	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
85569005466	ATP-grasp domain; Region: ATP-grasp; pfam02222
85569005467	Entner-Doudoroff aldolase; Region: eda; TIGR01182
85569005468	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
85569005469	active site
85569005470	intersubunit interface [polypeptide binding]; other site
85569005471	catalytic residue [active]
85569005472	phosphogluconate dehydratase; Validated; Region: PRK09054
85569005473	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
85569005474	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
85569005475	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
85569005476	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
85569005477	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
85569005478	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
85569005479	putative active site [active]
85569005480	pyruvate kinase; Provisional; Region: PRK05826
85569005481	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
85569005482	domain interfaces; other site
85569005483	active site
85569005484	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
85569005485	putative acyl-acceptor binding pocket; other site
85569005486	putative peptidase; Provisional; Region: PRK11649
85569005487	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
85569005488	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
85569005489	Peptidase family M23; Region: Peptidase_M23; pfam01551
85569005490	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
85569005491	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
85569005492	metal binding site [ion binding]; metal-binding site
85569005493	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
85569005494	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
85569005495	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
85569005496	ABC-ATPase subunit  interface; other site
85569005497	dimer interface [polypeptide binding]; other site
85569005498	putative PBP binding regions; other site
85569005499	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
85569005500	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569005501	Walker A motif; other site
85569005502	ATP binding site [chemical binding]; other site
85569005503	Walker B motif; other site
85569005504	arginine finger; other site
85569005505	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
85569005506	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
85569005507	RuvA N terminal domain; Region: RuvA_N; pfam01330
85569005508	Helix-hairpin-helix domain; Region: HHH_5; pfam14520
85569005509	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
85569005510	hypothetical protein; Provisional; Region: PRK11470
85569005511	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
85569005512	active site
85569005513	putative DNA-binding cleft [nucleotide binding]; other site
85569005514	dimer interface [polypeptide binding]; other site
85569005515	hypothetical protein; Validated; Region: PRK00110
85569005516	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
85569005517	nudix motif; other site
85569005518	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
85569005519	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
85569005520	dimer interface [polypeptide binding]; other site
85569005521	anticodon binding site; other site
85569005522	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
85569005523	homodimer interface [polypeptide binding]; other site
85569005524	motif 1; other site
85569005525	active site
85569005526	motif 2; other site
85569005527	GAD domain; Region: GAD; pfam02938
85569005528	motif 3; other site
85569005529	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
85569005530	catalytic triad [active]
85569005531	conserved cis-peptide bond; other site
85569005532	hypothetical protein; Provisional; Region: PRK10302
85569005533	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
85569005534	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569005535	S-adenosylmethionine binding site [chemical binding]; other site
85569005536	tRNA (mo5U34)-methyltransferase; Region: TIGR00452
85569005537	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569005538	S-adenosylmethionine binding site [chemical binding]; other site
85569005539	copper homeostasis protein CutC; Provisional; Region: PRK11572
85569005540	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
85569005541	putative metal binding site [ion binding]; other site
85569005542	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
85569005543	arginyl-tRNA synthetase; Region: argS; TIGR00456
85569005544	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
85569005545	active site
85569005546	HIGH motif; other site
85569005547	KMSK motif region; other site
85569005548	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
85569005549	tRNA binding surface [nucleotide binding]; other site
85569005550	anticodon binding site; other site
85569005551	penicillin-binding protein 2; Provisional; Region: PRK10795
85569005552	Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717
85569005553	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
85569005554	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
85569005555	Flagellar protein FlhE; Region: FlhE; pfam06366
85569005556	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
85569005557	FlhB HrpN YscU SpaS Family; Region: Bac_export_2; cl19167
85569005558	chemotaxis regulator CheZ; Provisional; Region: PRK11166
85569005559	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569005560	active site
85569005561	phosphorylation site [posttranslational modification]
85569005562	intermolecular recognition site; other site
85569005563	dimerization interface [polypeptide binding]; other site
85569005564	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
85569005565	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569005566	active site
85569005567	phosphorylation site [posttranslational modification]
85569005568	intermolecular recognition site; other site
85569005569	dimerization interface [polypeptide binding]; other site
85569005570	CheB methylesterase; Region: CheB_methylest; pfam01339
85569005571	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
85569005572	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
85569005573	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569005574	S-adenosylmethionine binding site [chemical binding]; other site
85569005575	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
85569005576	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
85569005577	dimer interface [polypeptide binding]; other site
85569005578	ligand binding site [chemical binding]; other site
85569005579	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569005580	dimerization interface [polypeptide binding]; other site
85569005581	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
85569005582	dimer interface [polypeptide binding]; other site
85569005583	putative CheW interface [polypeptide binding]; other site
85569005584	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
85569005585	putative CheA interaction surface; other site
85569005586	chemotaxis protein CheA; Provisional; Region: PRK10547
85569005587	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
85569005588	putative binding surface; other site
85569005589	active site
85569005590	CheY binding; Region: CheY-binding; pfam09078
85569005591	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
85569005592	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569005593	ATP binding site [chemical binding]; other site
85569005594	Mg2+ binding site [ion binding]; other site
85569005595	G-X-G motif; other site
85569005596	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
85569005597	flagellar motor protein MotB; Validated; Region: motB; PRK09041
85569005598	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
85569005599	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
85569005600	ligand binding site [chemical binding]; other site
85569005601	flagellar motor protein MotA; Validated; Region: PRK09110
85569005602	transcriptional activator FlhC; Provisional; Region: PRK12722
85569005603	transcriptional activator FlhD; Provisional; Region: PRK02909
85569005604	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
85569005605	Ligand Binding Site [chemical binding]; other site
85569005606	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
85569005607	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
85569005608	active site
85569005609	homotetramer interface [polypeptide binding]; other site
85569005610	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569005611	HAD-superfamily hydrolase, subfamily IIB; Region: HAD-SF-IIB; TIGR01484
85569005612	active site
85569005613	motif I; other site
85569005614	motif II; other site
85569005615	DJ-1 family protein; Region: not_thiJ; TIGR01383
85569005616	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
85569005617	conserved cys residue [active]
85569005618	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
85569005619	Ferritin-like domain; Region: Ferritin; pfam00210
85569005620	ferroxidase diiron center [ion binding]; other site
85569005621	hypothetical protein; Provisional; Region: PRK09273
85569005622	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
85569005623	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
85569005624	YecR-like lipoprotein; Region: YecR; pfam13992
85569005625	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
85569005626	Ferritin-like domain; Region: Ferritin; pfam00210
85569005627	ferroxidase diiron center [ion binding]; other site
85569005628	probable metal-binding protein; Region: matur_matur; TIGR03853
85569005629	tyrosine transporter TyrP; Provisional; Region: PRK15132
85569005630	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
85569005631	hypothetical protein; Provisional; Region: PRK10396
85569005632	yecA family protein; Region: ygfB_yecA; TIGR02292
85569005633	SEC-C motif; Region: SEC-C; pfam02810
85569005634	glucose-6-phosphate 1-dehydrogenase; Region: PLN02640
85569005635	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
85569005636	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
85569005637	NlpC/P60 family; Region: NLPC_P60; cl17555
85569005638	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
85569005639	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
85569005640	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
85569005641	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
85569005642	GIY-YIG motif/motif A; other site
85569005643	active site
85569005644	catalytic site [active]
85569005645	putative DNA binding site [nucleotide binding]; other site
85569005646	metal binding site [ion binding]; metal-binding site
85569005647	UvrB/uvrC motif; Region: UVR; pfam02151
85569005648	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
85569005649	Helix-hairpin-helix domain; Region: HHH_5; pfam14520
85569005650	response regulator; Provisional; Region: PRK09483
85569005651	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569005652	active site
85569005653	phosphorylation site [posttranslational modification]
85569005654	intermolecular recognition site; other site
85569005655	dimerization interface [polypeptide binding]; other site
85569005656	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569005657	DNA binding residues [nucleotide binding]
85569005658	dimerization interface [polypeptide binding]; other site
85569005659	hypothetical protein; Provisional; Region: PRK10613
85569005660	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
85569005661	Autoinducer binding domain; Region: Autoind_bind; pfam03472
85569005662	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569005663	DNA binding residues [nucleotide binding]
85569005664	dimerization interface [polypeptide binding]; other site
85569005665	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
85569005666	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
85569005667	Walker A/P-loop; other site
85569005668	ATP binding site [chemical binding]; other site
85569005669	Q-loop/lid; other site
85569005670	ABC transporter signature motif; other site
85569005671	Walker B; other site
85569005672	D-loop; other site
85569005673	H-loop/switch region; other site
85569005674	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
85569005675	amino acid ABC transporter permease; Provisional; Region: PRK15100
85569005676	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569005677	dimer interface [polypeptide binding]; other site
85569005678	conserved gate region; other site
85569005679	putative PBP binding loops; other site
85569005680	ABC-ATPase subunit interface; other site
85569005681	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
85569005682	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569005683	catalytic residue [active]
85569005684	cystine transporter subunit; Provisional; Region: PRK11260
85569005685	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
85569005686	substrate binding pocket [chemical binding]; other site
85569005687	membrane-bound complex binding site; other site
85569005688	hinge residues; other site
85569005689	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
85569005690	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
85569005691	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
85569005692	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
85569005693	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
85569005694	DNA binding residues [nucleotide binding]
85569005695	Transposase IS200 like; Region: Y1_Tnp; pfam01797
85569005696	flagellin; Validated; Region: PRK08026
85569005697	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
85569005698	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
85569005699	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
85569005700	flagellar capping protein; Reviewed; Region: fliD; PRK08032
85569005701	Flagellar hook-associated protein 2 N-terminus; Region: FliD_N; pfam02465
85569005702	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
85569005703	flagellar protein FliS; Validated; Region: fliS; PRK05685
85569005704	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
85569005705	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
85569005706	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
85569005707	active site
85569005708	Na/Ca binding site [ion binding]; other site
85569005709	catalytic site [active]
85569005710	lipoprotein; Provisional; Region: PRK10397
85569005711	putative inner membrane protein; Provisional; Region: PRK11099
85569005712	Predicted transporter component [General function prediction only]; Region: COG2391
85569005713	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
85569005714	CPxP  motif; other site
85569005715	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
85569005716	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
85569005717	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
85569005718	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
85569005719	flagellar motor switch protein FliG; Region: fliG; TIGR00207
85569005720	FliG N-terminal domain; Region: FliG_N; pfam14842
85569005721	FliG middle domain; Region: FliG_M; pfam14841
85569005722	FliG C-terminal domain; Region: FliG_C; pfam01706
85569005723	flagellar assembly protein H; Validated; Region: fliH; PRK05687
85569005724	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
85569005725	Flagellar assembly protein FliH; Region: FliH; pfam02108
85569005726	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
85569005727	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
85569005728	Walker A motif/ATP binding site; other site
85569005729	Walker B motif; other site
85569005730	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
85569005731	flagellar hook-length control protein; Provisional; Region: PRK10118
85569005732	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
85569005733	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
85569005734	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
85569005735	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
85569005736	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
85569005737	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
85569005738	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
85569005739	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
85569005740	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
85569005741	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
85569005742	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569005743	DNA binding residues [nucleotide binding]
85569005744	dimerization interface [polypeptide binding]; other site
85569005745	hypothetical protein; Provisional; Region: PRK10708
85569005746	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
85569005747	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
85569005748	mannosyl-3-phosphoglycerate phosphatase family; Region: HAD-SF-IIB-MPGP; TIGR01486
85569005749	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569005750	active site
85569005751	motif I; other site
85569005752	motif II; other site
85569005753	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
85569005754	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
85569005755	metal binding site [ion binding]; metal-binding site
85569005756	active site
85569005757	I-site; other site
85569005758	Uncharacterized small protein [Function unknown]; Region: COG5475
85569005759	hypothetical protein; Provisional; Region: PRK10062
85569005760	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
85569005761	EamA-like transporter family; Region: EamA; pfam00892
85569005762	EamA-like transporter family; Region: EamA; pfam00892
85569005763	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
85569005764	additional DNA contacts [nucleotide binding]; other site
85569005765	mismatch recognition site; other site
85569005766	active site
85569005767	zinc binding site [ion binding]; other site
85569005768	DNA intercalation site [nucleotide binding]; other site
85569005769	DNA cytosine methylase; Provisional; Region: PRK10458
85569005770	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
85569005771	cofactor binding site; other site
85569005772	DNA binding site [nucleotide binding]
85569005773	substrate interaction site [chemical binding]; other site
85569005774	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
85569005775	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
85569005776	Zn2+ binding site [ion binding]; other site
85569005777	Mg2+ binding site [ion binding]; other site
85569005778	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
85569005779	trimer interface [polypeptide binding]; other site
85569005780	eyelet of channel; other site
85569005781	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
85569005782	DNA-binding site [nucleotide binding]; DNA binding site
85569005783	RNA-binding motif; other site
85569005784	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
85569005785	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
85569005786	active site
85569005787	DNA binding site [nucleotide binding]
85569005788	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
85569005789	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
85569005790	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
85569005791	Catalytic site [active]
85569005792	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
85569005793	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
85569005794	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
85569005795	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; cl01542
85569005796	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
85569005797	Phage protein GP46; Region: GP46; pfam07409
85569005798	Bacteriophage Mu Gp45 protein; Region: Phage_Mu_Gp45; pfam06890
85569005799	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
85569005800	DNA circularisation protein N-terminus; Region: DNA_circ_N; pfam07157
85569005801	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
85569005802	Phage tail tube protein; Region: Tail_tube; pfam10618
85569005803	Mu-like prophage tail sheath protein gpL [General function prediction only]; Region: COG4386
85569005804	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
85569005805	Phage head-tail joining protein; Region: Phage_H_T_join; pfam05521
85569005806	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
85569005807	oligomerization interface [polypeptide binding]; other site
85569005808	Predicted phage phi-C31 gp36 major capsid-like protein [General function prediction only]; Region: COG4653
85569005809	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
85569005810	Caudovirus prohead protease; Region: Peptidase_U35; cl01521
85569005811	Phage portal protein; Region: Phage_portal; pfam04860
85569005812	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
85569005813	Phage Terminase; Region: Terminase_1; cl19862
85569005814	Phage terminase, small subunit; Region: Terminase_4; pfam05119
85569005815	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
85569005816	active site
85569005817	Predicted chitinase [General function prediction only]; Region: COG3179
85569005818	catalytic residue [active]
85569005819	Protein of unknown function (DUF754); Region: DUF754; pfam05449
85569005820	Antitermination protein; Region: Antiterm; pfam03589
85569005821	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cl19048
85569005822	Zn binding sites [ion binding]; other site
85569005823	Antitermination protein; Region: Antiterm; pfam03589
85569005824	Protein of unknown function (DUF968); Region: DUF968; pfam06147
85569005825	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
85569005826	active site
85569005827	KilA-N domain; Region: KilA-N; pfam04383
85569005828	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
85569005829	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; pfam05869
85569005830	PerC transcriptional activator; Region: PerC; pfam06069
85569005831	Helix-turn-helix domain; Region: HTH_36; pfam13730
85569005832	Ash protein family; Region: Phage_ASH; pfam10554
85569005833	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
85569005834	Predicted transcriptional regulator [Transcription]; Region: COG2932
85569005835	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569005836	non-specific DNA binding site [nucleotide binding]; other site
85569005837	salt bridge; other site
85569005838	sequence-specific DNA binding site [nucleotide binding]; other site
85569005839	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
85569005840	Catalytic site [active]
85569005841	Uncharacterized conserved protein (DUF2303); Region: DUF2303; pfam10065
85569005842	HD domain; Region: HD_3; cl17350
85569005843	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
85569005844	active site
85569005845	catalytic site [active]
85569005846	substrate binding site [chemical binding]; other site
85569005847	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
85569005848	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
85569005849	dimer interface [polypeptide binding]; other site
85569005850	active site
85569005851	Int/Topo IB signature motif; other site
85569005852	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
85569005853	putative protease; Region: PHA00666
85569005854	Phage integrase, N-terminal; Region: Phage_int_SAM_2; pfam12834
85569005855	Integrase; Region: Integrase_1; pfam12835
85569005856	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
85569005857	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
85569005858	Sel1 repeat; Region: Sel1; pfam08238
85569005859	Sel1-like repeats; Region: SEL1; smart00671
85569005860	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
85569005861	AMP nucleosidase; Provisional; Region: PRK08292
85569005862	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
85569005863	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
85569005864	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
85569005865	MATE family multidrug exporter; Provisional; Region: PRK10189
85569005866	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
85569005867	L,D-transpeptidase; Provisional; Region: PRK10190
85569005868	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
85569005869	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
85569005870	putative dimer interface [polypeptide binding]; other site
85569005871	active site pocket [active]
85569005872	putative cataytic base [active]
85569005873	cobalamin synthase; Reviewed; Region: cobS; PRK00235
85569005874	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
85569005875	homotrimer interface [polypeptide binding]; other site
85569005876	Walker A motif; other site
85569005877	GTP binding site [chemical binding]; other site
85569005878	Walker B motif; other site
85569005879	cobyric acid synthase; Provisional; Region: PRK00784
85569005880	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
85569005881	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
85569005882	catalytic triad [active]
85569005883	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13638
85569005884	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
85569005885	Walker A/P-loop; other site
85569005886	ATP binding site [chemical binding]; other site
85569005887	Q-loop/lid; other site
85569005888	ABC transporter signature motif; other site
85569005889	Walker B; other site
85569005890	D-loop; other site
85569005891	H-loop/switch region; other site
85569005892	cobalt transport protein CbiQ; Provisional; Region: PRK15485
85569005893	cobalt transport protein CbiN; Provisional; Region: PRK02898
85569005894	cobalt transport protein CbiM; Validated; Region: PRK08319
85569005895	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
85569005896	active site
85569005897	SAM binding site [chemical binding]; other site
85569005898	homodimer interface [polypeptide binding]; other site
85569005899	Cobalamin biosynthesis protein CbiK, Co2+ chelatase [Coenzyme metabolism]; Region: CbiK; COG4822
85569005900	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
85569005901	active site
85569005902	C-terminal domain interface [polypeptide binding]; other site
85569005903	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
85569005904	active site
85569005905	N-terminal domain interface [polypeptide binding]; other site
85569005906	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
85569005907	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
85569005908	active site
85569005909	SAM binding site [chemical binding]; other site
85569005910	homodimer interface [polypeptide binding]; other site
85569005911	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
85569005912	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
85569005913	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
85569005914	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
85569005915	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
85569005916	active site
85569005917	SAM binding site [chemical binding]; other site
85569005918	homodimer interface [polypeptide binding]; other site
85569005919	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569005920	S-adenosylmethionine binding site [chemical binding]; other site
85569005921	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
85569005922	active site
85569005923	putative homodimer interface [polypeptide binding]; other site
85569005924	SAM binding site [chemical binding]; other site
85569005925	Cobalamin biosynthesis protein CbiD [Coenzyme metabolism]; Region: CbiD; COG1903
85569005926	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
85569005927	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
85569005928	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
85569005929	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
85569005930	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
85569005931	catalytic triad [active]
85569005932	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
85569005933	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569005934	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
85569005935	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569005936	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
85569005937	amphipathic channel; other site
85569005938	Asn-Pro-Ala signature motifs; other site
85569005939	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
85569005940	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
85569005941	Hexamer interface [polypeptide binding]; other site
85569005942	Hexagonal pore residue; other site
85569005943	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutL; COG4816
85569005944	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduB_repeat1; cd07047
85569005945	putative hexamer interface [polypeptide binding]; other site
85569005946	putative hexagonal pore; other site
85569005947	1,2-propanediol utilization protein B (PduB), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduB_repeat2; cd07048
85569005948	putative hexamer interface [polypeptide binding]; other site
85569005949	putative hexagonal pore; other site
85569005950	Dehydratase large subunit. This family contains the large (alpha) subunit of B12-dependent glycerol dehydratases (GDHs) and B12-dependent diol dehydratases (DDHs). GDH is isofunctional with DDH. These enzymes can each catalyze the conversion of 1; Region: Dehydratase_LU; cd03687
85569005951	alpha-alpha subunit/dimer interface [polypeptide binding]; other site
85569005952	alpha-beta subunit interface [polypeptide binding]; other site
85569005953	alpha-gamma subunit interface [polypeptide binding]; other site
85569005954	active site
85569005955	substrate and K+ binding site; other site
85569005956	K+ binding site [ion binding]; other site
85569005957	cobalamin binding site [chemical binding]; other site
85569005958	propanediol dehydratase medium subunit; Provisional; Region: pduD; PRK15042
85569005959	Propanediol dehydratase, small subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduE; COG4910
85569005960	Cell division protein FtsA; Region: FtsA; cl17206
85569005961	Diol dehydratase reactivase ATPase-like domain; Region: DDR; pfam08841
85569005962	Dehydratase medium subunit; Region: Dehydratase_MU; pfam02288
85569005963	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
85569005964	1,2-propanediol utilization protein K (PduK), Bacterial Micro-Compartment (BMC) domain repeat 1l; Region: BMC_PduK; cd07056
85569005965	putative hexamer interface [polypeptide binding]; other site
85569005966	putative hexagonal pore; other site
85569005967	Propanediol utilization protein [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduL; COG4869
85569005968	Propanediol utilisation protein PduL; Region: PduL; pfam06130
85569005969	Propanediol utilisation protein PduL; Region: PduL; pfam06130
85569005970	putative propanediol utilization protein PduM; Provisional; Region: PRK15428
85569005971	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
85569005972	Hexamer/Pentamer interface [polypeptide binding]; other site
85569005973	central pore; other site
85569005974	cob(I)alamin adenosyltransferase [Coenzyme transport and    metabolism]; Region: COG2096
85569005975	Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193
85569005976	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
85569005977	putative catalytic cysteine [active]
85569005978	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
85569005979	putative active site [active]
85569005980	metal binding site [ion binding]; metal-binding site
85569005981	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
85569005982	SLBB domain; Region: SLBB; pfam10531
85569005983	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
85569005984	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
85569005985	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
85569005986	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
85569005987	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
85569005988	putative hexamer interface [polypeptide binding]; other site
85569005989	putative hexagonal pore; other site
85569005990	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
85569005991	putative hexamer interface [polypeptide binding]; other site
85569005992	putative hexagonal pore; other site
85569005993	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
85569005994	putative hexamer interface [polypeptide binding]; other site
85569005995	putative hexagonal pore; other site
85569005996	Ethanolamine utilisation - propanediol utilisation; Region: PduV-EutP; pfam10662
85569005997	G3 box; other site
85569005998	Switch II region; other site
85569005999	GTP/Mg2+ binding site [chemical binding]; other site
85569006000	G4 box; other site
85569006001	G5 box; other site
85569006002	propionate kinase; Reviewed; Region: PRK12397
85569006003	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
85569006004	hypothetical protein; Provisional; Region: PRK05423
85569006005	Predicted membrane protein [Function unknown]; Region: COG1289
85569006006	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
85569006007	DNA gyrase inhibitor; Provisional; Region: PRK10016
85569006008	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
85569006009	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
85569006010	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
85569006011	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
85569006012	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
85569006013	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
85569006014	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
85569006015	thiosulfate reductase PhsA; Provisional; Region: PRK15488
85569006016	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
85569006017	The MopB_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_Thiosulfate-R-like; cd02755
85569006018	putative [Fe4-S4] binding site [ion binding]; other site
85569006019	putative molybdopterin cofactor binding site [chemical binding]; other site
85569006020	The MopB_CT_Thiosulfate-R-like CD contains thiosulfate-, sulfur-, and polysulfide-reductases, and other related proteins. Thiosulfate reductase catalyzes the cleavage of sulfur-sulfur bonds in thiosulfate. Polysulfide reductase is a membrane-bound enzyme...; Region: MopB_CT_Thiosulfate-R-like; cd02778
85569006021	putative molybdopterin cofactor binding site; other site
85569006022	E3 ubiquitin-protein ligase SopA; Provisional; Region: PRK15377
85569006023	SopA-like central domain; Region: SopA; pfam13981
85569006024	SopA-like catalytic domain; Region: SopA_C; pfam13979
85569006025	exonuclease I; Provisional; Region: sbcB; PRK11779
85569006026	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
85569006027	active site
85569006028	catalytic site [active]
85569006029	substrate binding site [chemical binding]; other site
85569006030	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
85569006031	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
85569006032	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
85569006033	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569006034	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
85569006035	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
85569006036	dimerization interface [polypeptide binding]; other site
85569006037	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
85569006038	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
85569006039	putative NAD(P) binding site [chemical binding]; other site
85569006040	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
85569006041	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
85569006042	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
85569006043	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
85569006044	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
85569006045	NAD binding site [chemical binding]; other site
85569006046	dimerization interface [polypeptide binding]; other site
85569006047	product binding site; other site
85569006048	substrate binding site [chemical binding]; other site
85569006049	zinc binding site [ion binding]; other site
85569006050	catalytic residues [active]
85569006051	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
85569006052	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
85569006053	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569006054	homodimer interface [polypeptide binding]; other site
85569006055	catalytic residue [active]
85569006056	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
85569006057	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569006058	active site
85569006059	motif I; other site
85569006060	motif II; other site
85569006061	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
85569006062	putative active site pocket [active]
85569006063	4-fold oligomerization interface [polypeptide binding]; other site
85569006064	metal binding residues [ion binding]; metal-binding site
85569006065	3-fold/trimer interface [polypeptide binding]; other site
85569006066	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13142
85569006067	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
85569006068	putative active site [active]
85569006069	oxyanion strand; other site
85569006070	catalytic triad [active]
85569006071	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
85569006072	catalytic residues [active]
85569006073	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
85569006074	substrate binding site [chemical binding]; other site
85569006075	glutamase interaction surface [polypeptide binding]; other site
85569006076	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
85569006077	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
85569006078	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
85569006079	metal binding site [ion binding]; metal-binding site
85569006080	chain length determinant protein WzzB; Provisional; Region: PRK15471
85569006081	Chain length determinant protein; Region: Wzz; pfam02706
85569006082	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
85569006083	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
85569006084	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl19126
85569006085	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
85569006086	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
85569006087	Transposase IS200 like; Region: Y1_Tnp; pfam01797
85569006088	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
85569006089	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
85569006090	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
85569006091	undecaprenyl-phosphate galactose phosphotransferase; Provisional; Region: PRK15204
85569006092	CoA binding domain; Region: CoA_binding; cl17356
85569006093	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
85569006094	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
85569006095	ManB is a bacterial phosphomannomutase (PMM) that catalyzes the conversion of mannose 6-phosphate to mannose-1-phosphate in the second of three steps in the GDP-mannose pathway, in which GDP-D-mannose is synthesized from fructose-6-phosphate. In...; Region: ManB; cd03088
85569006096	active site
85569006097	substrate binding site [chemical binding]; other site
85569006098	metal binding site [ion binding]; metal-binding site
85569006099	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
85569006100	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
85569006101	Substrate binding site; other site
85569006102	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
85569006103	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
85569006104	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
85569006105	active site
85569006106	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
85569006107	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
85569006108	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
85569006109	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
85569006110	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
85569006111	active site
85569006112	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cd12082
85569006113	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
85569006114	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
85569006115	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
85569006116	NAD(P) binding site [chemical binding]; other site
85569006117	active site
85569006118	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
85569006119	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
85569006120	inhibitor-cofactor binding pocket; inhibition site
85569006121	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569006122	catalytic residue [active]
85569006123	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
85569006124	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
85569006125	NAD binding site [chemical binding]; other site
85569006126	homotetramer interface [polypeptide binding]; other site
85569006127	homodimer interface [polypeptide binding]; other site
85569006128	substrate binding site [chemical binding]; other site
85569006129	active site
85569006130	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
85569006131	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
85569006132	substrate binding site; other site
85569006133	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
85569006134	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
85569006135	catalytic loop [active]
85569006136	iron binding site [ion binding]; other site
85569006137	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
85569006138	FAD binding pocket [chemical binding]; other site
85569006139	FAD binding motif [chemical binding]; other site
85569006140	phosphate binding motif [ion binding]; other site
85569006141	beta-alpha-beta structure motif; other site
85569006142	NAD binding pocket [chemical binding]; other site
85569006143	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
85569006144	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
85569006145	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
85569006146	substrate binding site; other site
85569006147	tetramer interface; other site
85569006148	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
85569006149	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
85569006150	NADP binding site [chemical binding]; other site
85569006151	active site
85569006152	putative substrate binding site [chemical binding]; other site
85569006153	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
85569006154	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
85569006155	NAD binding site [chemical binding]; other site
85569006156	substrate binding site [chemical binding]; other site
85569006157	homodimer interface [polypeptide binding]; other site
85569006158	active site
85569006159	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
85569006160	active site
85569006161	tetramer interface; other site
85569006162	colanic acid biosynthesis protein WcaM; Region: WcaM; TIGR04004
85569006163	colanic acid biosynthesis glycosyltransferase WcaL; Provisional; Region: PRK15427
85569006164	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
85569006165	putative ADP-binding pocket [chemical binding]; other site
85569006166	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
85569006167	colanic acid exporter; Provisional; Region: PRK10459
85569006168	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
85569006169	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
85569006170	CoA-binding domain; Region: CoA_binding_3; pfam13727
85569006171	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
85569006172	phosphomannomutase CpsG; Provisional; Region: PRK15414
85569006173	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
85569006174	active site
85569006175	substrate binding site [chemical binding]; other site
85569006176	metal binding site [ion binding]; metal-binding site
85569006177	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
85569006178	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
85569006179	Substrate binding site; other site
85569006180	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
85569006181	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
85569006182	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
85569006183	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
85569006184	active site
85569006185	GDP-Mannose binding site [chemical binding]; other site
85569006186	modified nudix motif
85569006187	dimer interface [polypeptide binding]; other site
85569006188	metal binding site [ion binding]; metal-binding site
85569006189	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
85569006190	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
85569006191	NADP binding site [chemical binding]; other site
85569006192	active site
85569006193	putative substrate binding site [chemical binding]; other site
85569006194	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
85569006195	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
85569006196	NADP-binding site; other site
85569006197	homotetramer interface [polypeptide binding]; other site
85569006198	substrate binding site [chemical binding]; other site
85569006199	homodimer interface [polypeptide binding]; other site
85569006200	active site
85569006201	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
85569006202	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
85569006203	putative trimer interface [polypeptide binding]; other site
85569006204	putative active site [active]
85569006205	putative substrate binding site [chemical binding]; other site
85569006206	putative CoA binding site [chemical binding]; other site
85569006207	colanic acid biosynthesis glycosyl transferase WcaE; Region: wcaE; TIGR04009
85569006208	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
85569006209	metal-binding site
85569006210	putative colanic acid biosynthesis protein; Provisional; Region: wcaD; cl08075
85569006211	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
85569006212	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
85569006213	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
85569006214	putative acyl transferase; Provisional; Region: PRK10191
85569006215	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
85569006216	trimer interface [polypeptide binding]; other site
85569006217	active site
85569006218	substrate binding site [chemical binding]; other site
85569006219	CoA binding site [chemical binding]; other site
85569006220	putative glycosyl transferase; Provisional; Region: PRK10018
85569006221	colanic acid biosynthesis glycosyl transferase WcaA; Region: WcaA; TIGR04017
85569006222	active site
85569006223	tyrosine kinase; Provisional; Region: PRK11519
85569006224	Chain length determinant protein; Region: Wzz; pfam02706
85569006225	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
85569006226	AAA domain; Region: AAA_31; pfam13614
85569006227	Low molecular weight phosphatase family; Region: LMWPc; cd00115
85569006228	active site
85569006229	polysaccharide export protein Wza; Provisional; Region: PRK15078
85569006230	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
85569006231	SLBB domain; Region: SLBB; pfam10531
85569006232	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
85569006233	FOG: CBS domain [General function prediction only]; Region: COG0517
85569006234	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
85569006235	Transporter associated domain; Region: CorC_HlyC; smart01091
85569006236	putative assembly protein; Provisional; Region: PRK10833
85569006237	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
85569006238	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
85569006239	trimer interface [polypeptide binding]; other site
85569006240	active site
85569006241	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
85569006242	ATP-binding site [chemical binding]; other site
85569006243	Sugar specificity; other site
85569006244	Pyrimidine base specificity; other site
85569006245	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
85569006246	putative diguanylate cyclase; Provisional; Region: PRK09776
85569006247	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
85569006248	putative active site [active]
85569006249	heme pocket [chemical binding]; other site
85569006250	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
85569006251	putative active site [active]
85569006252	heme pocket [chemical binding]; other site
85569006253	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
85569006254	metal binding site [ion binding]; metal-binding site
85569006255	active site
85569006256	I-site; other site
85569006257	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
85569006258	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
85569006259	AlkA N-terminal domain; Region: AlkA_N; pfam06029
85569006260	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
85569006261	minor groove reading motif; other site
85569006262	helix-hairpin-helix signature motif; other site
85569006263	substrate binding pocket [chemical binding]; other site
85569006264	active site
85569006265	putative chaperone; Provisional; Region: PRK11678
85569006266	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
85569006267	nucleotide binding site [chemical binding]; other site
85569006268	putative NEF/HSP70 interaction site [polypeptide binding]; other site
85569006269	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
85569006270	SBD interface [polypeptide binding]; other site
85569006271	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
85569006272	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
85569006273	HlyD family secretion protein; Region: HlyD_3; pfam13437
85569006274	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
85569006275	MMPL family; Region: MMPL; cl14618
85569006276	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
85569006277	MMPL family; Region: MMPL; cl14618
85569006278	putative transporter; Provisional; Region: PRK10504
85569006279	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569006280	putative substrate translocation pore; other site
85569006281	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
85569006282	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569006283	dimerization interface [polypeptide binding]; other site
85569006284	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569006285	dimer interface [polypeptide binding]; other site
85569006286	phosphorylation site [posttranslational modification]
85569006287	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569006288	ATP binding site [chemical binding]; other site
85569006289	Mg2+ binding site [ion binding]; other site
85569006290	G-X-G motif; other site
85569006291	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
85569006292	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569006293	active site
85569006294	phosphorylation site [posttranslational modification]
85569006295	intermolecular recognition site; other site
85569006296	dimerization interface [polypeptide binding]; other site
85569006297	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
85569006298	DNA binding site [nucleotide binding]
85569006299	PcfJ-like protein; Region: PcfJ; pfam14284
85569006300	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
85569006301	Domain of unknown function (DUF4034); Region: DUF4034; pfam13226
85569006302	putative protease; Provisional; Region: PRK15452
85569006303	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
85569006304	type III secretion system protein; Provisional; Region: PRK15383
85569006305	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
85569006306	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
85569006307	putative active site; other site
85569006308	catalytic residue [active]
85569006309	Nucleoside H+ symporter; Region: Nuc_H_symport; pfam03825
85569006310	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569006311	putative substrate translocation pore; other site
85569006312	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
85569006313	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
85569006314	substrate binding site [chemical binding]; other site
85569006315	ATP binding site [chemical binding]; other site
85569006316	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
85569006317	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569006318	DNA-binding site [nucleotide binding]; DNA binding site
85569006319	UTRA domain; Region: UTRA; pfam07702
85569006320	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
85569006321	dimer interface [polypeptide binding]; other site
85569006322	substrate binding site [chemical binding]; other site
85569006323	ATP binding site [chemical binding]; other site
85569006324	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
85569006325	substrate binding site [chemical binding]; other site
85569006326	multimerization interface [polypeptide binding]; other site
85569006327	ATP binding site [chemical binding]; other site
85569006328	Predicted integral membrane protein [Function unknown]; Region: COG5455
85569006329	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
85569006330	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
85569006331	PapC N-terminal domain; Region: PapC_N; pfam13954
85569006332	Outer membrane usher protein; Region: Usher; pfam00577
85569006333	PapC C-terminal domain; Region: PapC_C; pfam13953
85569006334	putative fimbrial assembly chaperone protein StcB; Provisional; Region: PRK15253
85569006335	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
85569006336	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
85569006337	fimbrial chaperone protein; Provisional; Region: PRK15220
85569006338	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
85569006339	antiporter inner membrane protein; Provisional; Region: PRK11670
85569006340	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
85569006341	Walker A motif; other site
85569006342	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
85569006343	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
85569006344	active site
85569006345	HIGH motif; other site
85569006346	KMSKS motif; other site
85569006347	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
85569006348	tRNA binding surface [nucleotide binding]; other site
85569006349	anticodon binding site; other site
85569006350	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
85569006351	dimer interface [polypeptide binding]; other site
85569006352	putative tRNA-binding site [nucleotide binding]; other site
85569006353	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
85569006354	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
85569006355	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
85569006356	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
85569006357	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
85569006358	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
85569006359	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569006360	active site
85569006361	phosphorylation site [posttranslational modification]
85569006362	intermolecular recognition site; other site
85569006363	dimerization interface [polypeptide binding]; other site
85569006364	LytTr DNA-binding domain; Region: LytTR; pfam04397
85569006365	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
85569006366	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
85569006367	GAF domain; Region: GAF; pfam01590
85569006368	Histidine kinase; Region: His_kinase; pfam06580
85569006369	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569006370	ATP binding site [chemical binding]; other site
85569006371	Mg2+ binding site [ion binding]; other site
85569006372	G-X-G motif; other site
85569006373	transcriptional regulator MirA; Provisional; Region: PRK15043
85569006374	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
85569006375	DNA binding residues [nucleotide binding]
85569006376	hypothetical protein; Provisional; Region: PRK13681
85569006377	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569006378	dimer interface [polypeptide binding]; other site
85569006379	conserved gate region; other site
85569006380	putative PBP binding loops; other site
85569006381	ABC-ATPase subunit interface; other site
85569006382	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
85569006383	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569006384	Walker A/P-loop; other site
85569006385	ATP binding site [chemical binding]; other site
85569006386	Q-loop/lid; other site
85569006387	ABC transporter signature motif; other site
85569006388	Walker B; other site
85569006389	D-loop; other site
85569006390	H-loop/switch region; other site
85569006391	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
85569006392	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569006393	dimer interface [polypeptide binding]; other site
85569006394	conserved gate region; other site
85569006395	putative PBP binding loops; other site
85569006396	ABC-ATPase subunit interface; other site
85569006397	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
85569006398	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
85569006399	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
85569006400	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
85569006401	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
85569006402	D-lactate dehydrogenase; Provisional; Region: PRK11183
85569006403	FAD binding domain; Region: FAD_binding_4; cl19922
85569006404	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
85569006405	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
85569006406	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
85569006407	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
85569006408	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
85569006409	oxidoreductase; Provisional; Region: PRK12743
85569006410	classical (c) SDRs; Region: SDR_c; cd05233
85569006411	NAD(P) binding site [chemical binding]; other site
85569006412	active site
85569006413	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
85569006414	Outer membrane efflux protein; Region: OEP; pfam02321
85569006415	Outer membrane efflux protein; Region: OEP; pfam02321
85569006416	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
85569006417	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
85569006418	FMN binding site [chemical binding]; other site
85569006419	active site
85569006420	catalytic residues [active]
85569006421	substrate binding site [chemical binding]; other site
85569006422	salicylate hydroxylase; Provisional; Region: PRK08163
85569006423	Squalene epoxidase; Region: SE; cl17314
85569006424	GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042
85569006425	maleylacetoacetate isomerase; Region: maiA; TIGR01262
85569006426	C-terminal domain interface [polypeptide binding]; other site
85569006427	GSH binding site (G-site) [chemical binding]; other site
85569006428	putative dimer interface [polypeptide binding]; other site
85569006429	C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191
85569006430	dimer interface [polypeptide binding]; other site
85569006431	N-terminal domain interface [polypeptide binding]; other site
85569006432	maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site
85569006433	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
85569006434	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
85569006435	gentisate 1,2-dioxygenase; Region: gentisate_1_2; TIGR02272
85569006436	Cupin domain; Region: Cupin_2; pfam07883
85569006437	Cupin domain; Region: Cupin_2; cl17218
85569006438	benzoate transport; Region: 2A0115; TIGR00895
85569006439	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569006440	putative substrate translocation pore; other site
85569006441	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
85569006442	hypothetical protein; Provisional; Region: PRK01821
85569006443	hypothetical protein; Provisional; Region: PRK10711
85569006444	cytidine deaminase; Provisional; Region: PRK09027
85569006445	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
85569006446	active site
85569006447	catalytic motif [active]
85569006448	Zn binding site [ion binding]; other site
85569006449	Cytidine and deoxycytidylate deaminase zinc-binding region; Region: dCMP_cyt_deam_2; pfam08211
85569006450	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
85569006451	active site
85569006452	catalytic motif [active]
85569006453	Zn binding site [ion binding]; other site
85569006454	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
85569006455	putative active site [active]
85569006456	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
85569006457	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
85569006458	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster; Region: Fer4_20; pfam14691
85569006459	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569006460	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
85569006461	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
85569006462	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
85569006463	homodimer interface [polypeptide binding]; other site
85569006464	active site
85569006465	FMN binding site [chemical binding]; other site
85569006466	substrate binding site [chemical binding]; other site
85569006467	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569006468	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
85569006469	TM-ABC transporter signature motif; other site
85569006470	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
85569006471	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
85569006472	Walker A/P-loop; other site
85569006473	ATP binding site [chemical binding]; other site
85569006474	Q-loop/lid; other site
85569006475	ABC transporter signature motif; other site
85569006476	Walker B; other site
85569006477	D-loop; other site
85569006478	H-loop/switch region; other site
85569006479	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
85569006480	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
85569006481	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
85569006482	ligand binding site [chemical binding]; other site
85569006483	calcium binding site [ion binding]; other site
85569006484	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
85569006485	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
85569006486	DNA binding site [nucleotide binding]
85569006487	domain linker motif; other site
85569006488	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
85569006489	dimerization interface (closed form) [polypeptide binding]; other site
85569006490	ligand binding site [chemical binding]; other site
85569006491	Predicted membrane protein [Function unknown]; Region: COG2311
85569006492	hypothetical protein; Provisional; Region: PRK10835
85569006493	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
85569006494	homodecamer interface [polypeptide binding]; other site
85569006495	active site
85569006496	putative catalytic site residues [active]
85569006497	zinc binding site [ion binding]; other site
85569006498	GTP-CH-I/GFRP interaction surface; other site
85569006499	Predicted esterase [General function prediction only]; Region: COG0627
85569006500	S-formylglutathione hydrolase; Region: PLN02442
85569006501	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
85569006502	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569006503	non-specific DNA binding site [nucleotide binding]; other site
85569006504	salt bridge; other site
85569006505	sequence-specific DNA binding site [nucleotide binding]; other site
85569006506	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
85569006507	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
85569006508	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
85569006509	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
85569006510	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
85569006511	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569006512	motif II; other site
85569006513	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
85569006514	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569006515	putative substrate translocation pore; other site
85569006516	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
85569006517	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
85569006518	N-terminal plug; other site
85569006519	ligand-binding site [chemical binding]; other site
85569006520	lysine transporter; Provisional; Region: PRK10836
85569006521	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
85569006522	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
85569006523	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569006524	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
85569006525	putative dimerization interface [polypeptide binding]; other site
85569006526	conserved hypothetical integral membrane protein; Region: TIGR00698
85569006527	Endonuclease IV [DNA replication, recombination, and repair]; Region: Nfo; COG0648
85569006528	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
85569006529	AP (apurinic/apyrimidinic) site pocket; other site
85569006530	DNA interaction; other site
85569006531	Metal-binding active site; metal-binding site
85569006532	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
85569006533	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
85569006534	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
85569006535	active site
85569006536	P-loop; other site
85569006537	phosphorylation site [posttranslational modification]
85569006538	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
85569006539	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
85569006540	putative substrate binding site [chemical binding]; other site
85569006541	putative ATP binding site [chemical binding]; other site
85569006542	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
85569006543	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
85569006544	active site
85569006545	phosphorylation site [posttranslational modification]
85569006546	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
85569006547	dimerization domain swap beta strand [polypeptide binding]; other site
85569006548	regulatory protein interface [polypeptide binding]; other site
85569006549	active site
85569006550	regulatory phosphorylation site [posttranslational modification]; other site
85569006551	sugar efflux transporter B; Provisional; Region: PRK15011
85569006552	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569006553	putative substrate translocation pore; other site
85569006554	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
85569006555	elongation factor P; Provisional; Region: PRK04542
85569006556	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
85569006557	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
85569006558	RNA binding site [nucleotide binding]; other site
85569006559	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
85569006560	RNA binding site [nucleotide binding]; other site
85569006561	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
85569006562	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
85569006563	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; cl08458
85569006564	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
85569006565	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
85569006566	active site
85569006567	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
85569006568	NlpC/P60 family; Region: NLPC_P60; pfam00877
85569006569	phage resistance protein; Provisional; Region: PRK10551
85569006570	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
85569006571	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
85569006572	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
85569006573	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
85569006574	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
85569006575	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569006576	dimer interface [polypeptide binding]; other site
85569006577	conserved gate region; other site
85569006578	putative PBP binding loops; other site
85569006579	ABC-ATPase subunit interface; other site
85569006580	microcin C ABC transporter permease; Provisional; Region: PRK15021
85569006581	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569006582	dimer interface [polypeptide binding]; other site
85569006583	conserved gate region; other site
85569006584	putative PBP binding loops; other site
85569006585	ABC-ATPase subunit interface; other site
85569006586	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
85569006587	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
85569006588	Walker A/P-loop; other site
85569006589	ATP binding site [chemical binding]; other site
85569006590	Q-loop/lid; other site
85569006591	ABC transporter signature motif; other site
85569006592	Walker B; other site
85569006593	D-loop; other site
85569006594	H-loop/switch region; other site
85569006595	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
85569006596	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
85569006597	Walker A/P-loop; other site
85569006598	ATP binding site [chemical binding]; other site
85569006599	Q-loop/lid; other site
85569006600	ABC transporter signature motif; other site
85569006601	Walker B; other site
85569006602	D-loop; other site
85569006603	H-loop/switch region; other site
85569006604	hypothetical protein; Provisional; Region: PRK11835
85569006605	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569006606	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
85569006607	putative substrate translocation pore; other site
85569006608	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
85569006609	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
85569006610	RNA binding surface [nucleotide binding]; other site
85569006611	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
85569006612	active site
85569006613	uracil binding [chemical binding]; other site
85569006614	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
85569006615	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
85569006616	ATP binding site [chemical binding]; other site
85569006617	putative Mg++ binding site [ion binding]; other site
85569006618	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
85569006619	nucleotide binding region [chemical binding]; other site
85569006620	ATP-binding site [chemical binding]; other site
85569006621	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
85569006622	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
85569006623	5S rRNA interface [nucleotide binding]; other site
85569006624	CTC domain interface [polypeptide binding]; other site
85569006625	L16 interface [polypeptide binding]; other site
85569006626	nucleoid-associated protein NdpA; Validated; Region: PRK00378
85569006627	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
85569006628	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
85569006629	Sulfatase; Region: Sulfatase; cl19157
85569006630	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
85569006631	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
85569006632	Catalytic site [active]
85569006633	DinI-like family; Region: DinI; cl11630
85569006634	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
85569006635	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
85569006636	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
85569006637	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
85569006638	Phage T4 tail fibre; Region: Phage_T4_gp36; pfam03903
85569006639	Phage head maturation protease [General function prediction only]; Region: COG3740
85569006640	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
85569006641	Phage portal protein; Region: Phage_portal; cl19194
85569006642	Predicted P-loop ATPase [General function prediction only]; Region: COG4928
85569006643	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
85569006644	Protein of unknown function (DUF968); Region: DUF968; pfam06147
85569006645	E3 ubiquitin-protein ligase SspH2; Provisional; Region: PRK15387
85569006646	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
85569006647	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
85569006648	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
85569006649	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
85569006650	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cd00116
85569006651	Leucine-rich repeats; other site
85569006652	C-terminal novel E3 ligase, LRR-interacting; Region: NEL; pfam14496
85569006653	DinI-like family; Region: DinI; cl11630
85569006654	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
85569006655	transcriptional regulator NarP; Provisional; Region: PRK10403
85569006656	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569006657	active site
85569006658	phosphorylation site [posttranslational modification]
85569006659	intermolecular recognition site; other site
85569006660	dimerization interface [polypeptide binding]; other site
85569006661	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569006662	DNA binding residues [nucleotide binding]
85569006663	dimerization interface [polypeptide binding]; other site
85569006664	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
85569006665	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
85569006666	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
85569006667	catalytic residues [active]
85569006668	central insert; other site
85569006669	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
85569006670	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
85569006671	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
85569006672	heme exporter protein CcmC; Region: ccmC; TIGR01191
85569006673	heme exporter protein CcmB; Region: ccmB; TIGR01190
85569006674	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
85569006675	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
85569006676	Walker A/P-loop; other site
85569006677	ATP binding site [chemical binding]; other site
85569006678	Q-loop/lid; other site
85569006679	ABC transporter signature motif; other site
85569006680	Walker B; other site
85569006681	D-loop; other site
85569006682	H-loop/switch region; other site
85569006683	cytochrome c-type protein NapC; Provisional; Region: PRK10617
85569006684	cytochrome c nitrate reductase, small subunit; Region: cytochr_NrfH; TIGR03153
85569006685	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
85569006686	UbiA family of prenyltransferases (PTases); Region: PT_UbiA; cl00337
85569006687	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
85569006688	4Fe-4S binding domain; Region: Fer4_5; pfam12801
85569006689	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569006690	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
85569006691	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569006692	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569006693	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569006694	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
85569006695	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
85569006696	[4Fe-4S] binding site [ion binding]; other site
85569006697	molybdopterin cofactor binding site; other site
85569006698	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
85569006699	molybdopterin cofactor binding site; other site
85569006700	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
85569006701	ferredoxin-type protein; Provisional; Region: PRK10194
85569006702	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569006703	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
85569006704	secondary substrate binding site; other site
85569006705	primary substrate binding site; other site
85569006706	inhibition loop; other site
85569006707	dimerization interface [polypeptide binding]; other site
85569006708	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
85569006709	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
85569006710	Walker A/P-loop; other site
85569006711	ATP binding site [chemical binding]; other site
85569006712	Q-loop/lid; other site
85569006713	ABC transporter signature motif; other site
85569006714	Walker B; other site
85569006715	D-loop; other site
85569006716	H-loop/switch region; other site
85569006717	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
85569006718	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
85569006719	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
85569006720	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569006721	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
85569006722	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
85569006723	DNA binding site [nucleotide binding]
85569006724	active site
85569006725	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
85569006726	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
85569006727	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
85569006728	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569006729	ATP binding site [chemical binding]; other site
85569006730	G-X-G motif; other site
85569006731	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
85569006732	putative binding surface; other site
85569006733	active site
85569006734	transcriptional regulator RcsB; Provisional; Region: PRK10840
85569006735	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569006736	active site
85569006737	phosphorylation site [posttranslational modification]
85569006738	intermolecular recognition site; other site
85569006739	dimerization interface [polypeptide binding]; other site
85569006740	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569006741	DNA binding residues [nucleotide binding]
85569006742	dimerization interface [polypeptide binding]; other site
85569006743	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
85569006744	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569006745	dimer interface [polypeptide binding]; other site
85569006746	phosphorylation site [posttranslational modification]
85569006747	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569006748	ATP binding site [chemical binding]; other site
85569006749	Mg2+ binding site [ion binding]; other site
85569006750	G-X-G motif; other site
85569006751	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
85569006752	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569006753	active site
85569006754	phosphorylation site [posttranslational modification]
85569006755	intermolecular recognition site; other site
85569006756	dimerization interface [polypeptide binding]; other site
85569006757	DNA gyrase subunit A; Validated; Region: PRK05560
85569006758	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
85569006759	CAP-like domain; other site
85569006760	active site
85569006761	primary dimer interface [polypeptide binding]; other site
85569006762	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
85569006763	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
85569006764	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
85569006765	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
85569006766	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
85569006767	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
85569006768	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
85569006769	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
85569006770	active site pocket [active]
85569006771	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
85569006772	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569006773	putative substrate translocation pore; other site
85569006774	Transcriptional regulators [Transcription]; Region: GntR; COG1802
85569006775	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569006776	DNA-binding site [nucleotide binding]; DNA binding site
85569006777	FCD domain; Region: FCD; pfam07729
85569006778	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
85569006779	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569006780	S-adenosylmethionine binding site [chemical binding]; other site
85569006781	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
85569006782	ATP cone domain; Region: ATP-cone; pfam03477
85569006783	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
85569006784	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
85569006785	dimer interface [polypeptide binding]; other site
85569006786	putative radical transfer pathway; other site
85569006787	diiron center [ion binding]; other site
85569006788	tyrosyl radical; other site
85569006789	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
85569006790	catalytic loop [active]
85569006791	iron binding site [ion binding]; other site
85569006792	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
85569006793	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569006794	putative substrate translocation pore; other site
85569006795	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
85569006796	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569006797	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
85569006798	dimerization interface [polypeptide binding]; other site
85569006799	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
85569006800	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
85569006801	active site
85569006802	catalytic site [active]
85569006803	metal binding site [ion binding]; metal-binding site
85569006804	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
85569006805	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569006806	putative substrate translocation pore; other site
85569006807	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
85569006808	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569006809	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
85569006810	FAD binding domain; Region: FAD_binding_2; pfam00890
85569006811	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
85569006812	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
85569006813	Cysteine-rich domain; Region: CCG; pfam02754
85569006814	Cysteine-rich domain; Region: CCG; pfam02754
85569006815	deubiquitinase SseL; Provisional; Region: PRK14848
85569006816	hypothetical protein; Provisional; Region: PRK03673
85569006817	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
85569006818	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
85569006819	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569006820	putative substrate translocation pore; other site
85569006821	L-rhamnonate dehydratase; Provisional; Region: PRK15440
85569006822	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
85569006823	putative active site pocket [active]
85569006824	putative metal binding site [ion binding]; other site
85569006825	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
85569006826	Transcriptional regulator [Transcription]; Region: IclR; COG1414
85569006827	Bacterial transcriptional regulator; Region: IclR; pfam01614
85569006828	hypothetical protein; Provisional; Region: PRK03673
85569006829	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
85569006830	putative MPT binding site; other site
85569006831	Competence-damaged protein; Region: CinA; cl00666
85569006832	YfaZ precursor; Region: YfaZ; pfam07437
85569006833	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
85569006834	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
85569006835	catalytic core [active]
85569006836	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
85569006837	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
85569006838	inhibitor-cofactor binding pocket; inhibition site
85569006839	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569006840	catalytic residue [active]
85569006841	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
85569006842	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
85569006843	Ligand binding site; other site
85569006844	Putative Catalytic site; other site
85569006845	DXD motif; other site
85569006846	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
85569006847	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
85569006848	active site
85569006849	substrate binding site [chemical binding]; other site
85569006850	cosubstrate binding site; other site
85569006851	catalytic site [active]
85569006852	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
85569006853	active site
85569006854	hexamer interface [polypeptide binding]; other site
85569006855	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
85569006856	NAD binding site [chemical binding]; other site
85569006857	substrate binding site [chemical binding]; other site
85569006858	active site
85569006859	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
85569006860	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
85569006861	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
85569006862	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
85569006863	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
85569006864	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
85569006865	Polymyxin resistance protein PmrD; Region: PmrD; pfam11183
85569006866	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
85569006867	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
85569006868	acyl-activating enzyme (AAE) consensus motif; other site
85569006869	putative AMP binding site [chemical binding]; other site
85569006870	putative active site [active]
85569006871	putative CoA binding site [chemical binding]; other site
85569006872	O-succinylbenzoate synthase [Coenzyme metabolism]; Region: MenC; COG1441
85569006873	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
85569006874	active site
85569006875	dihydroxynaphthoic acid synthetase; Validated; Region: PRK07396
85569006876	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
85569006877	substrate binding site [chemical binding]; other site
85569006878	oxyanion hole (OAH) forming residues; other site
85569006879	trimer interface [polypeptide binding]; other site
85569006880	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
85569006881	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Region: menH_SHCHC; TIGR03695
85569006882	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
85569006883	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
85569006884	dimer interface [polypeptide binding]; other site
85569006885	tetramer interface [polypeptide binding]; other site
85569006886	PYR/PP interface [polypeptide binding]; other site
85569006887	TPP binding site [chemical binding]; other site
85569006888	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
85569006889	TPP-binding site; other site
85569006890	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
85569006891	isochorismate synthases; Region: isochor_syn; TIGR00543
85569006892	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569006893	Coenzyme A binding pocket [chemical binding]; other site
85569006894	ribonuclease BN; Region: true_RNase_BN; TIGR02649
85569006895	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
85569006896	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569006897	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
85569006898	active site
85569006899	phosphorylation site [posttranslational modification]
85569006900	intermolecular recognition site; other site
85569006901	dimerization interface [polypeptide binding]; other site
85569006902	von Willebrand factor; Region: vWF_A; pfam12450
85569006903	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
85569006904	VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subgroup; cd01465
85569006905	metal ion-dependent adhesion site (MIDAS); other site
85569006906	Domain of unknown function (DUF3520); Region: DUF3520; pfam12034
85569006907	NADH dehydrogenase subunit 2; Provisional; Region: ND2; MTH00200
85569006908	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
85569006909	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
85569006910	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
85569006911	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
85569006912	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
85569006913	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
85569006914	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
85569006915	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
85569006916	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
85569006917	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569006918	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
85569006919	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
85569006920	NADH dehydrogenase subunit G; Validated; Region: PRK08166
85569006921	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
85569006922	catalytic loop [active]
85569006923	iron binding site [ion binding]; other site
85569006924	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
85569006925	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
85569006926	[4Fe-4S] binding site [ion binding]; other site
85569006927	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
85569006928	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
85569006929	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
85569006930	SLBB domain; Region: SLBB; pfam10531
85569006931	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
85569006932	NADH:ubiquinone oxidoreductase 24 kD subunit [Energy production and conversion]; Region: NuoE; COG1905
85569006933	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
85569006934	putative dimer interface [polypeptide binding]; other site
85569006935	[2Fe-2S] cluster binding site [ion binding]; other site
85569006936	NADH:ubiquinone oxidoreductase 27 kD subunit [Energy production and conversion]; Region: NuoC; COG0852
85569006937	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
85569006938	Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Region: Complex1_49kDa; cl19174
85569006939	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
85569006940	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
85569006941	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
85569006942	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569006943	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
85569006944	putative dimerization interface [polypeptide binding]; other site
85569006945	aminotransferase AlaT; Validated; Region: PRK09265
85569006946	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
85569006947	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569006948	homodimer interface [polypeptide binding]; other site
85569006949	catalytic residue [active]
85569006950	5'-nucleotidase; Provisional; Region: PRK03826
85569006951	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
85569006952	transmembrane helices; other site
85569006953	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
85569006954	TrkA-C domain; Region: TrkA_C; pfam02080
85569006955	TrkA-C domain; Region: TrkA_C; pfam02080
85569006956	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
85569006957	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
85569006958	putative phosphatase; Provisional; Region: PRK11587
85569006959	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569006960	active site
85569006961	motif I; other site
85569006962	motif II; other site
85569006963	hypothetical protein; Validated; Region: PRK05445
85569006964	hypothetical protein; Provisional; Region: PRK01816
85569006965	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
85569006966	phosphate acetyltransferase; Reviewed; Region: PRK05632
85569006967	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
85569006968	DRTGG domain; Region: DRTGG; pfam07085
85569006969	phosphate acetyltransferase; Region: pta; TIGR00651
85569006970	hypothetical protein; Provisional; Region: PRK11588
85569006971	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
85569006972	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
85569006973	PYR/PP interface [polypeptide binding]; other site
85569006974	dimer interface [polypeptide binding]; other site
85569006975	TPP binding site [chemical binding]; other site
85569006976	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
85569006977	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
85569006978	TPP-binding site [chemical binding]; other site
85569006979	dimer interface [polypeptide binding]; other site
85569006980	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK12996
85569006981	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
85569006982	active site
85569006983	P-loop; other site
85569006984	phosphorylation site [posttranslational modification]
85569006985	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
85569006986	active site
85569006987	phosphorylation site [posttranslational modification]
85569006988	Transcriptional regulators [Transcription]; Region: PurR; COG1609
85569006989	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
85569006990	DNA binding site [nucleotide binding]
85569006991	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
85569006992	putative dimerization interface [polypeptide binding]; other site
85569006993	putative ligand binding site [chemical binding]; other site
85569006994	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
85569006995	nudix motif; other site
85569006996	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
85569006997	active site
85569006998	metal binding site [ion binding]; metal-binding site
85569006999	homotetramer interface [polypeptide binding]; other site
85569007000	glutathione S-transferase; Provisional; Region: PRK15113
85569007001	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
85569007002	C-terminal domain interface [polypeptide binding]; other site
85569007003	GSH binding site (G-site) [chemical binding]; other site
85569007004	dimer interface [polypeptide binding]; other site
85569007005	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
85569007006	N-terminal domain interface [polypeptide binding]; other site
85569007007	putative dimer interface [polypeptide binding]; other site
85569007008	putative substrate binding pocket (H-site) [chemical binding]; other site
85569007009	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
85569007010	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
85569007011	C-terminal domain interface [polypeptide binding]; other site
85569007012	GSH binding site (G-site) [chemical binding]; other site
85569007013	dimer interface [polypeptide binding]; other site
85569007014	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
85569007015	N-terminal domain interface [polypeptide binding]; other site
85569007016	putative dimer interface [polypeptide binding]; other site
85569007017	active site
85569007018	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
85569007019	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
85569007020	putative NAD(P) binding site [chemical binding]; other site
85569007021	putative active site [active]
85569007022	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
85569007023	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
85569007024	Walker A/P-loop; other site
85569007025	ATP binding site [chemical binding]; other site
85569007026	Q-loop/lid; other site
85569007027	ABC transporter signature motif; other site
85569007028	Walker B; other site
85569007029	D-loop; other site
85569007030	H-loop/switch region; other site
85569007031	ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism]; Region: ArtM; COG4160
85569007032	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569007033	dimer interface [polypeptide binding]; other site
85569007034	conserved gate region; other site
85569007035	putative PBP binding loops; other site
85569007036	ABC-ATPase subunit interface; other site
85569007037	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
85569007038	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569007039	dimer interface [polypeptide binding]; other site
85569007040	conserved gate region; other site
85569007041	putative PBP binding loops; other site
85569007042	ABC-ATPase subunit interface; other site
85569007043	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
85569007044	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
85569007045	substrate binding pocket [chemical binding]; other site
85569007046	membrane-bound complex binding site; other site
85569007047	hinge residues; other site
85569007048	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
85569007049	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
85569007050	substrate binding pocket [chemical binding]; other site
85569007051	membrane-bound complex binding site; other site
85569007052	hinge residues; other site
85569007053	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
85569007054	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
85569007055	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
85569007056	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
85569007057	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815
85569007058	dimer interface [polypeptide binding]; other site
85569007059	active site
85569007060	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
85569007061	substrate binding site [chemical binding]; other site
85569007062	catalytic residue [active]
85569007063	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
85569007064	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
85569007065	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
85569007066	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
85569007067	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
85569007068	catalytic residue [active]
85569007069	PAS fold; Region: PAS_4; pfam08448
85569007070	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
85569007071	putative active site [active]
85569007072	heme pocket [chemical binding]; other site
85569007073	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
85569007074	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569007075	Walker A motif; other site
85569007076	ATP binding site [chemical binding]; other site
85569007077	Walker B motif; other site
85569007078	arginine finger; other site
85569007079	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
85569007080	amidophosphoribosyltransferase; Provisional; Region: PRK09246
85569007081	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
85569007082	active site
85569007083	tetramer interface [polypeptide binding]; other site
85569007084	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
85569007085	active site
85569007086	colicin V production protein; Provisional; Region: PRK10845
85569007087	cell division protein DedD; Provisional; Region: PRK11633
85569007088	Sporulation related domain; Region: SPOR; pfam05036
85569007089	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
85569007090	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
85569007091	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
85569007092	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
85569007093	hypothetical protein; Provisional; Region: PRK10847
85569007094	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
85569007095	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
85569007096	dimerization interface 3.5A [polypeptide binding]; other site
85569007097	active site
85569007098	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
85569007099	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118
85569007100	Semialdehyde dehydrogenase, dimerization domain; Region: Semialdhyde_dhC; pfam02774
85569007101	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
85569007102	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
85569007103	ligand binding site [chemical binding]; other site
85569007104	NAD binding site [chemical binding]; other site
85569007105	catalytic site [active]
85569007106	homodimer interface [polypeptide binding]; other site
85569007107	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
85569007108	putative transporter; Provisional; Region: PRK12382
85569007109	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569007110	putative substrate translocation pore; other site
85569007111	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569007112	non-specific DNA binding site [nucleotide binding]; other site
85569007113	salt bridge; other site
85569007114	sequence-specific DNA binding site [nucleotide binding]; other site
85569007115	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
85569007116	CAAX protease self-immunity; Region: Abi; pfam02517
85569007117	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
85569007118	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
85569007119	dimer interface [polypeptide binding]; other site
85569007120	active site
85569007121	Uncharacterized conserved protein [Function unknown]; Region: COG4121
85569007122	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
85569007123	tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain; Region: MnmC_Cterm; TIGR03197
85569007124	YfcL protein; Region: YfcL; pfam08891
85569007125	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
85569007126	hypothetical protein; Provisional; Region: PRK10621
85569007127	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
85569007128	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
85569007129	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
85569007130	Tetramer interface [polypeptide binding]; other site
85569007131	active site
85569007132	FMN-binding site [chemical binding]; other site
85569007133	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK11805
85569007134	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569007135	S-adenosylmethionine binding site [chemical binding]; other site
85569007136	hypothetical protein; Provisional; Region: PRK04946
85569007137	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
85569007138	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
85569007139	catalytic core [active]
85569007140	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
85569007141	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
85569007142	substrate binding site [chemical binding]; other site
85569007143	oxyanion hole (OAH) forming residues; other site
85569007144	trimer interface [polypeptide binding]; other site
85569007145	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
85569007146	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
85569007147	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
85569007148	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
85569007149	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
85569007150	dimer interface [polypeptide binding]; other site
85569007151	active site
85569007152	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
85569007153	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
85569007154	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
85569007155	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
85569007156	Outer membrane protease [Cell envelope biogenesis, outer membrane]; Region: OmpT; COG4571
85569007157	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
85569007158	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569007159	active site
85569007160	phosphorylation site [posttranslational modification]
85569007161	intermolecular recognition site; other site
85569007162	dimerization interface [polypeptide binding]; other site
85569007163	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl18944
85569007164	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
85569007165	Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms]; Region: COG4192
85569007166	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569007167	dimerization interface [polypeptide binding]; other site
85569007168	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569007169	dimer interface [polypeptide binding]; other site
85569007170	phosphorylation site [posttranslational modification]
85569007171	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569007172	ATP binding site [chemical binding]; other site
85569007173	Mg2+ binding site [ion binding]; other site
85569007174	G-X-G motif; other site
85569007175	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
85569007176	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
85569007177	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569007178	putative substrate translocation pore; other site
85569007179	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
85569007180	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
85569007181	putative acyl-acceptor binding pocket; other site
85569007182	aminotransferase; Validated; Region: PRK08175
85569007183	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
85569007184	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569007185	homodimer interface [polypeptide binding]; other site
85569007186	catalytic residue [active]
85569007187	glucokinase; Provisional; Region: glk; PRK00292
85569007188	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
85569007189	Cl- selectivity filter; other site
85569007190	Cl- binding residues [ion binding]; other site
85569007191	pore gating glutamate residue; other site
85569007192	dimer interface [polypeptide binding]; other site
85569007193	Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes [Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only]; Region: COG3961
85569007194	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
85569007195	dimer interface [polypeptide binding]; other site
85569007196	PYR/PP interface [polypeptide binding]; other site
85569007197	TPP binding site [chemical binding]; other site
85569007198	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
85569007199	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
85569007200	TPP-binding site [chemical binding]; other site
85569007201	dimer interface [polypeptide binding]; other site
85569007202	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
85569007203	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
85569007204	active site
85569007205	catalytic tetrad [active]
85569007206	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
85569007207	manganese transport protein MntH; Reviewed; Region: PRK00701
85569007208	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
85569007209	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
85569007210	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
85569007211	Nucleoside recognition; Region: Gate; pfam07670
85569007212	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
85569007213	MASE1; Region: MASE1; pfam05231
85569007214	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
85569007215	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
85569007216	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
85569007217	Winged helix-turn helix; Region: HTH_29; pfam13551
85569007218	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569007219	salt bridge; other site
85569007220	non-specific DNA binding site [nucleotide binding]; other site
85569007221	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
85569007222	sequence-specific DNA binding site [nucleotide binding]; other site
85569007223	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
85569007224	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
85569007225	active site
85569007226	HIGH motif; other site
85569007227	KMSKS motif; other site
85569007228	Protein of unknown function (DUF3150); Region: DUF3150; pfam11348
85569007229	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
85569007230	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569007231	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
85569007232	putative dimerization interface [polypeptide binding]; other site
85569007233	putative substrate binding pocket [chemical binding]; other site
85569007234	purine nucleoside phosphorylase; Provisional; Region: PRK08202
85569007235	Purine nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pnp; COG0005
85569007236	hypothetical protein; Provisional; Region: PRK11528
85569007237	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569007238	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569007239	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
85569007240	putative dimerization interface [polypeptide binding]; other site
85569007241	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
85569007242	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
85569007243	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
85569007244	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
85569007245	nucleotide binding pocket [chemical binding]; other site
85569007246	K-X-D-G motif; other site
85569007247	catalytic site [active]
85569007248	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
85569007249	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
85569007250	Helix-hairpin-helix domain; Region: HHH_5; pfam14520
85569007251	Helix-hairpin-helix motif; Region: HHH_2; pfam12826
85569007252	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
85569007253	Dimer interface [polypeptide binding]; other site
85569007254	BRCT sequence motif; other site
85569007255	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
85569007256	cell division protein ZipA; Provisional; Region: PRK03427
85569007257	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
85569007258	FtsZ protein binding site [polypeptide binding]; other site
85569007259	putative sulfate transport protein CysZ; Validated; Region: PRK04949
85569007260	cysteine synthase; Region: PLN02565
85569007261	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
85569007262	dimer interface [polypeptide binding]; other site
85569007263	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569007264	catalytic residue [active]
85569007265	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
85569007266	dimerization domain swap beta strand [polypeptide binding]; other site
85569007267	regulatory protein interface [polypeptide binding]; other site
85569007268	active site
85569007269	regulatory phosphorylation site [posttranslational modification]; other site
85569007270	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
85569007271	PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524
85569007272	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
85569007273	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
85569007274	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
85569007275	HPr interaction site; other site
85569007276	glycerol kinase (GK) interaction site [polypeptide binding]; other site
85569007277	active site
85569007278	phosphorylation site [posttranslational modification]
85569007279	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
85569007280	dimer interface [polypeptide binding]; other site
85569007281	pyridoxal binding site [chemical binding]; other site
85569007282	ATP binding site [chemical binding]; other site
85569007283	transcriptional regulatory protein PtsJ; Provisional; Region: PRK15481
85569007284	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569007285	DNA-binding site [nucleotide binding]; DNA binding site
85569007286	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
85569007287	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569007288	homodimer interface [polypeptide binding]; other site
85569007289	catalytic residue [active]
85569007290	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
85569007291	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
85569007292	catalytic triad [active]
85569007293	hypothetical protein; Provisional; Region: PRK10318
85569007294	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
85569007295	Transglycosylase; Region: Transgly; cl19357
85569007296	cysteine synthase; Region: PLN02565
85569007297	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
85569007298	dimer interface [polypeptide binding]; other site
85569007299	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569007300	catalytic residue [active]
85569007301	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
85569007302	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569007303	Walker A/P-loop; other site
85569007304	ATP binding site [chemical binding]; other site
85569007305	Q-loop/lid; other site
85569007306	ABC transporter signature motif; other site
85569007307	Walker B; other site
85569007308	D-loop; other site
85569007309	H-loop/switch region; other site
85569007310	TOBE-like domain; Region: TOBE_3; pfam12857
85569007311	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
85569007312	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569007313	dimer interface [polypeptide binding]; other site
85569007314	conserved gate region; other site
85569007315	putative PBP binding loops; other site
85569007316	ABC-ATPase subunit interface; other site
85569007317	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
85569007318	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569007319	dimer interface [polypeptide binding]; other site
85569007320	conserved gate region; other site
85569007321	putative PBP binding loops; other site
85569007322	ABC-ATPase subunit interface; other site
85569007323	thiosulfate transporter subunit; Provisional; Region: PRK10852
85569007324	short chain dehydrogenase; Provisional; Region: PRK08226
85569007325	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
85569007326	NAD binding site [chemical binding]; other site
85569007327	homotetramer interface [polypeptide binding]; other site
85569007328	homodimer interface [polypeptide binding]; other site
85569007329	active site
85569007330	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
85569007331	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
85569007332	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
85569007333	putative acetyltransferase; Provisional; Region: PRK03624
85569007334	Uncharacterized conserved protein [Function unknown]; Region: COG3375
85569007335	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569007336	Coenzyme A binding pocket [chemical binding]; other site
85569007337	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
85569007338	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
85569007339	active site
85569007340	metal binding site [ion binding]; metal-binding site
85569007341	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
85569007342	transcriptional regulator EutR; Provisional; Region: PRK10130
85569007343	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569007344	carboxysome structural protein EutK; Provisional; Region: PRK15466
85569007345	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
85569007346	Hexamer interface [polypeptide binding]; other site
85569007347	Hexagonal pore residue; other site
85569007348	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
85569007349	Bacterial Micro-Compartment (BMC) domain; Region: BMC; cl01982
85569007350	Hexamer interface [polypeptide binding]; other site
85569007351	Hexagonal pore residue; other site
85569007352	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
85569007353	putative hexamer interface [polypeptide binding]; other site
85569007354	putative hexagonal pore; other site
85569007355	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
85569007356	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
85569007357	Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition [Amino acid transport and metabolism]; Region: EutA; COG4819
85569007358	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
85569007359	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
85569007360	active site
85569007361	metal binding site [ion binding]; metal-binding site
85569007362	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
85569007363	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
85569007364	nucleotide binding site [chemical binding]; other site
85569007365	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
85569007366	nucleotide binding site [chemical binding]; other site
85569007367	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
85569007368	putative catalytic cysteine [active]
85569007369	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
85569007370	Hexamer/Pentamer interface [polypeptide binding]; other site
85569007371	central pore; other site
85569007372	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
85569007373	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
85569007374	Hexamer interface [polypeptide binding]; other site
85569007375	Hexagonal pore residue; other site
85569007376	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
85569007377	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
85569007378	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
85569007379	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
85569007380	G1 box; other site
85569007381	GTP/Mg2+ binding site [chemical binding]; other site
85569007382	G2 box; other site
85569007383	Switch I region; other site
85569007384	G3 box; other site
85569007385	Switch II region; other site
85569007386	G4 box; other site
85569007387	G5 box; other site
85569007388	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
85569007389	putative hexamer interface [polypeptide binding]; other site
85569007390	putative hexagonal pore; other site
85569007391	Transposase IS200 like; Region: Y1_Tnp; pfam01797
85569007392	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
85569007393	Malic enzyme, N-terminal domain; Region: malic; pfam00390
85569007394	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
85569007395	putative NAD(P) binding site [chemical binding]; other site
85569007396	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
85569007397	transaldolase-like protein; Provisional; Region: PTZ00411
85569007398	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
85569007399	active site
85569007400	dimer interface [polypeptide binding]; other site
85569007401	catalytic residue [active]
85569007402	transketolase; Reviewed; Region: PRK12753
85569007403	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
85569007404	TPP-binding site [chemical binding]; other site
85569007405	dimer interface [polypeptide binding]; other site
85569007406	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
85569007407	PYR/PP interface [polypeptide binding]; other site
85569007408	dimer interface [polypeptide binding]; other site
85569007409	TPP binding site [chemical binding]; other site
85569007410	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
85569007411	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
85569007412	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
85569007413	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
85569007414	dimer interface [polypeptide binding]; other site
85569007415	ADP-ribose binding site [chemical binding]; other site
85569007416	active site
85569007417	nudix motif; other site
85569007418	metal binding site [ion binding]; metal-binding site
85569007419	putative periplasmic esterase; Provisional; Region: PRK03642
85569007420	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
85569007421	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569007422	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster; Region: Fer4_20; pfam14691
85569007423	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569007424	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
85569007425	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
85569007426	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
85569007427	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569007428	dimerization interface [polypeptide binding]; other site
85569007429	Histidine kinase; Region: HisKA_3; pfam07730
85569007430	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569007431	ATP binding site [chemical binding]; other site
85569007432	Mg2+ binding site [ion binding]; other site
85569007433	G-X-G motif; other site
85569007434	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
85569007435	MMPL family; Region: MMPL; cl14618
85569007436	MMPL family; Region: MMPL; cl14618
85569007437	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
85569007438	putative catalytic residues [active]
85569007439	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
85569007440	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
85569007441	metal binding site [ion binding]; metal-binding site
85569007442	dimer interface [polypeptide binding]; other site
85569007443	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
85569007444	Domain of unknown function (DUF1726); Region: DUF1726; pfam08351
85569007445	Helicase; Region: Helicase_RecD; pfam05127
85569007446	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
85569007447	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
85569007448	Predicted metalloprotease [General function prediction only]; Region: COG2321
85569007449	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
85569007450	ATP binding site [chemical binding]; other site
85569007451	active site
85569007452	substrate binding site [chemical binding]; other site
85569007453	lipoprotein; Provisional; Region: PRK11679
85569007454	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
85569007455	dimer interface [polypeptide binding]; other site
85569007456	active site
85569007457	catalytic residue [active]
85569007458	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
85569007459	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
85569007460	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
85569007461	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
85569007462	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
85569007463	catalytic triad [active]
85569007464	Transposase IS200 like; Region: Y1_Tnp; pfam01797
85569007465	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
85569007466	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
85569007467	Peptidase family M48; Region: Peptidase_M48; cl12018
85569007468	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
85569007469	catalytic residues [active]
85569007470	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
85569007471	DNA replication initiation factor; Provisional; Region: PRK08084
85569007472	uracil transporter; Provisional; Region: PRK10720
85569007473	uracil-xanthine permease; Region: ncs2; TIGR00801
85569007474	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
85569007475	active site
85569007476	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
85569007477	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
85569007478	dimerization interface [polypeptide binding]; other site
85569007479	putative ATP binding site [chemical binding]; other site
85569007480	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
85569007481	active site
85569007482	substrate binding site [chemical binding]; other site
85569007483	cosubstrate binding site; other site
85569007484	catalytic site [active]
85569007485	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
85569007486	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
85569007487	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
85569007488	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
85569007489	putative active site [active]
85569007490	catalytic site [active]
85569007491	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
85569007492	domain interface [polypeptide binding]; other site
85569007493	active site
85569007494	catalytic site [active]
85569007495	exopolyphosphatase; Provisional; Region: PRK10854
85569007496	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
85569007497	nucleotide binding site [chemical binding]; other site
85569007498	MASE1; Region: MASE1; pfam05231
85569007499	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
85569007500	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
85569007501	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
85569007502	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
85569007503	Integrase core domain; Region: rve; pfam00665
85569007504	GMP synthase; Reviewed; Region: guaA; PRK00074
85569007505	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
85569007506	AMP/PPi binding site [chemical binding]; other site
85569007507	candidate oxyanion hole; other site
85569007508	catalytic triad [active]
85569007509	potential glutamine specificity residues [chemical binding]; other site
85569007510	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
85569007511	ATP Binding subdomain [chemical binding]; other site
85569007512	Ligand Binding sites [chemical binding]; other site
85569007513	Dimerization subdomain; other site
85569007514	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
85569007515	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
85569007516	active site
85569007517	Domain in cystathionine beta-synthase and other proteins; Region: CBS; smart00116
85569007518	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
85569007519	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
85569007520	generic binding surface II; other site
85569007521	generic binding surface I; other site
85569007522	AIDA autotransporter-like protein ShdA; Provisional; Region: PRK15319
85569007523	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
85569007524	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
85569007525	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
85569007526	Autotransporter beta-domain; Region: Autotransporter; smart00869
85569007527	outer membrane protein RatA; Provisional; Region: PRK15315
85569007528	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
85569007529	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
85569007530	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
85569007531	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
85569007532	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
85569007533	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
85569007534	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
85569007535	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
85569007536	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
85569007537	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
85569007538	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
85569007539	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
85569007540	intimin-like protein SinH; Provisional; Region: PRK15318
85569007541	zinc-ribbons; Region: zinc-ribbons_6; pfam07191
85569007542	GTP-binding protein Der; Reviewed; Region: PRK00093
85569007543	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
85569007544	G1 box; other site
85569007545	GTP/Mg2+ binding site [chemical binding]; other site
85569007546	Switch I region; other site
85569007547	G2 box; other site
85569007548	Switch II region; other site
85569007549	G3 box; other site
85569007550	G4 box; other site
85569007551	G5 box; other site
85569007552	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
85569007553	G1 box; other site
85569007554	GTP/Mg2+ binding site [chemical binding]; other site
85569007555	Switch I region; other site
85569007556	G2 box; other site
85569007557	G3 box; other site
85569007558	Switch II region; other site
85569007559	G4 box; other site
85569007560	G5 box; other site
85569007561	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal; Region: KH_dom-like; pfam14714
85569007562	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
85569007563	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
85569007564	Trp docking motif [polypeptide binding]; other site
85569007565	active site
85569007566	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
85569007567	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4649
85569007568	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
85569007569	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
85569007570	dimer interface [polypeptide binding]; other site
85569007571	motif 1; other site
85569007572	active site
85569007573	motif 2; other site
85569007574	motif 3; other site
85569007575	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
85569007576	anticodon binding site; other site
85569007577	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
85569007578	1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Region: ispG_gcpE; TIGR00612
85569007579	cytoskeletal protein RodZ; Provisional; Region: PRK10856
85569007580	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569007581	non-specific DNA binding site [nucleotide binding]; other site
85569007582	salt bridge; other site
85569007583	sequence-specific DNA binding site [nucleotide binding]; other site
85569007584	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
85569007585	23S rRNA m2A2503 methyltransferase; Region: TIGR00048
85569007586	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569007587	FeS/SAM binding site; other site
85569007588	Nucleoside diphosphate kinase; Region: NDK; pfam00334
85569007589	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
85569007590	active site
85569007591	multimer interface [polypeptide binding]; other site
85569007592	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569007593	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569007594	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
85569007595	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
85569007596	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
85569007597	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
85569007598	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
85569007599	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
85569007600	putative [Fe4-S4] binding site [ion binding]; other site
85569007601	putative molybdopterin cofactor binding site [chemical binding]; other site
85569007602	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
85569007603	putative molybdopterin cofactor binding site; other site
85569007604	penicillin-binding protein 1C; Provisional; Region: PRK11240
85569007605	Transglycosylase; Region: Transgly; pfam00912
85569007606	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
85569007607	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
85569007608	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
85569007609	MG2 domain; Region: A2M_N; pfam01835
85569007610	Alpha-2-macroglobulin family N-terminal region; Region: A2M_N_2; pfam07703
85569007611	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
85569007612	surface patch; other site
85569007613	thioester region; other site
85569007614	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
85569007615	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
85569007616	active site residue [active]
85569007617	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
85569007618	active site residue [active]
85569007619	SseB protein N-terminal domain; Region: SseB; pfam07179
85569007620	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
85569007621	SseB protein C-terminal domain; Region: SseB_C; pfam14581
85569007622	aminopeptidase B; Provisional; Region: PRK05015
85569007623	Peptidase; Region: DUF3663; pfam12404
85569007624	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
85569007625	interface (dimer of trimers) [polypeptide binding]; other site
85569007626	Substrate-binding/catalytic site; other site
85569007627	Zn-binding sites [ion binding]; other site
85569007628	hypothetical protein; Provisional; Region: PRK10721
85569007629	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
85569007630	catalytic loop [active]
85569007631	iron binding site [ion binding]; other site
85569007632	chaperone protein HscA; Provisional; Region: hscA; PRK05183
85569007633	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
85569007634	nucleotide binding site [chemical binding]; other site
85569007635	putative NEF/HSP70 interaction site [polypeptide binding]; other site
85569007636	SBD interface [polypeptide binding]; other site
85569007637	co-chaperone HscB; Provisional; Region: hscB; PRK05014
85569007638	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
85569007639	HSP70 interaction site [polypeptide binding]; other site
85569007640	HSCB C-terminal oligomerization domain; Region: HSCB_C; pfam07743
85569007641	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
85569007642	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
85569007643	trimerization site [polypeptide binding]; other site
85569007644	active site
85569007645	cysteine desulfurase; Provisional; Region: PRK14012
85569007646	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
85569007647	catalytic residue [active]
85569007648	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
85569007649	Rrf2 family protein; Region: rrf2_super; TIGR00738
85569007650	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
85569007651	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
85569007652	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
85569007653	active site
85569007654	dimerization interface [polypeptide binding]; other site
85569007655	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
85569007656	Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144
85569007657	anaerobic sulfite reductase subunit A; Provisional; Region: PRK15055
85569007658	sulfite reductase, subunit A; Region: sulfite_red_A; TIGR02910
85569007659	anaerobic sulfite reductase subunit B; Provisional; Region: PRK08221
85569007660	Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is...; Region: sulfite_reductase_like; cd06221
85569007661	FAD binding pocket [chemical binding]; other site
85569007662	FAD binding motif [chemical binding]; other site
85569007663	phosphate binding motif [ion binding]; other site
85569007664	beta-alpha-beta structure motif; other site
85569007665	NAD binding pocket [chemical binding]; other site
85569007666	Iron coordination center [ion binding]; other site
85569007667	sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912
85569007668	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
85569007669	Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077
85569007670	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569007671	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
85569007672	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
85569007673	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
85569007674	PRD domain; Region: PRD; pfam00874
85569007675	PRD domain; Region: PRD; pfam00874
85569007676	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569007677	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
85569007678	putative substrate translocation pore; other site
85569007679	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
85569007680	dimer interface [polypeptide binding]; other site
85569007681	active site
85569007682	glycine-pyridoxal phosphate binding site [chemical binding]; other site
85569007683	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
85569007684	folate binding site [chemical binding]; other site
85569007685	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
85569007686	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
85569007687	heme-binding site [chemical binding]; other site
85569007688	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
85569007689	FAD binding pocket [chemical binding]; other site
85569007690	FAD binding motif [chemical binding]; other site
85569007691	phosphate binding motif [ion binding]; other site
85569007692	beta-alpha-beta structure motif; other site
85569007693	NAD binding pocket [chemical binding]; other site
85569007694	Heme binding  pocket [chemical binding]; other site
85569007695	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
85569007696	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
85569007697	DNA binding site [nucleotide binding]
85569007698	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
85569007699	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
85569007700	lysine decarboxylase CadA; Provisional; Region: PRK15400
85569007701	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
85569007702	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
85569007703	homodimer interface [polypeptide binding]; other site
85569007704	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569007705	catalytic residue [active]
85569007706	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
85569007707	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
85569007708	POT family; Region: PTR2; cl17359
85569007709	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569007710	putative substrate translocation pore; other site
85569007711	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
85569007712	response regulator GlrR; Provisional; Region: PRK15115
85569007713	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569007714	active site
85569007715	phosphorylation site [posttranslational modification]
85569007716	intermolecular recognition site; other site
85569007717	dimerization interface [polypeptide binding]; other site
85569007718	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569007719	Walker A motif; other site
85569007720	ATP binding site [chemical binding]; other site
85569007721	Walker B motif; other site
85569007722	arginine finger; other site
85569007723	hypothetical protein; Provisional; Region: PRK10722
85569007724	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
85569007725	HAMP domain; Region: HAMP; pfam00672
85569007726	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569007727	dimer interface [polypeptide binding]; other site
85569007728	phosphorylation site [posttranslational modification]
85569007729	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569007730	ATP binding site [chemical binding]; other site
85569007731	Mg2+ binding site [ion binding]; other site
85569007732	G-X-G motif; other site
85569007733	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
85569007734	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
85569007735	dimerization interface [polypeptide binding]; other site
85569007736	ATP binding site [chemical binding]; other site
85569007737	Formylglycinamide ribonucleotide amidotransferase (FGAR-AT) catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, phosphate, and glutamate in the fourth step of...; Region: PurL; cd02193
85569007738	dimerization interface [polypeptide binding]; other site
85569007739	ATP binding site [chemical binding]; other site
85569007740	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
85569007741	putative active site [active]
85569007742	catalytic triad [active]
85569007743	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
85569007744	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
85569007745	substrate binding pocket [chemical binding]; other site
85569007746	membrane-bound complex binding site; other site
85569007747	hinge residues; other site
85569007748	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
85569007749	N-acetyl-D-glucosamine binding site [chemical binding]; other site
85569007750	catalytic residue [active]
85569007751	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
85569007752	nucleoside/Zn binding site; other site
85569007753	dimer interface [polypeptide binding]; other site
85569007754	catalytic motif [active]
85569007755	hypothetical protein; Provisional; Region: PRK11590
85569007756	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
85569007757	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
85569007758	active site turn [active]
85569007759	phosphorylation site [posttranslational modification]
85569007760	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
85569007761	N-acetylmuramic acid 6-phosphate etherase; Region: TIGR00274
85569007762	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
85569007763	putative active site [active]
85569007764	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
85569007765	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
85569007766	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
85569007767	putative active site [active]
85569007768	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
85569007769	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
85569007770	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
85569007771	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
85569007772	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569007773	putative substrate translocation pore; other site
85569007774	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569007775	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569007776	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
85569007777	dimerization interface [polypeptide binding]; other site
85569007778	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
85569007779	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
85569007780	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
85569007781	active site
85569007782	hydrophilic channel; other site
85569007783	dimerization interface [polypeptide binding]; other site
85569007784	catalytic residues [active]
85569007785	active site lid [active]
85569007786	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
85569007787	Recombination protein O N terminal; Region: RecO_N; pfam11967
85569007788	Recombination protein O C terminal; Region: RecO_C; pfam02565
85569007789	GTPase Era; Reviewed; Region: era; PRK00089
85569007790	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
85569007791	G1 box; other site
85569007792	GTP/Mg2+ binding site [chemical binding]; other site
85569007793	Switch I region; other site
85569007794	G2 box; other site
85569007795	Switch II region; other site
85569007796	G3 box; other site
85569007797	G4 box; other site
85569007798	G5 box; other site
85569007799	KH domain; Region: KH_2; pfam07650
85569007800	ribonuclease III; Reviewed; Region: rnc; PRK00102
85569007801	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
85569007802	dimerization interface [polypeptide binding]; other site
85569007803	active site
85569007804	metal binding site [ion binding]; metal-binding site
85569007805	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
85569007806	dsRNA binding site [nucleotide binding]; other site
85569007807	signal peptidase I; Provisional; Region: PRK10861
85569007808	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
85569007809	Catalytic site [active]
85569007810	GTP-binding protein LepA; Provisional; Region: PRK05433
85569007811	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
85569007812	G1 box; other site
85569007813	putative GEF interaction site [polypeptide binding]; other site
85569007814	GTP/Mg2+ binding site [chemical binding]; other site
85569007815	Switch I region; other site
85569007816	G2 box; other site
85569007817	G3 box; other site
85569007818	Switch II region; other site
85569007819	G4 box; other site
85569007820	G5 box; other site
85569007821	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
85569007822	Elongation Factor G, domain II; Region: EFG_II; pfam14492
85569007823	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
85569007824	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
85569007825	type III secretion protein GogB; Provisional; Region: PRK15386
85569007826	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
85569007827	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
85569007828	DNA-binding interface [nucleotide binding]; DNA binding site
85569007829	Phage-encoded virulence factor; Region: PAGK; pfam15284
85569007830	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
85569007831	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cl00019
85569007832	ADP-ribose binding site [chemical binding]; other site
85569007833	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
85569007834	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
85569007835	Phage Tail Collar Domain; Region: Collar; pfam07484
85569007836	Phage-related protein, tail component [Function unknown]; Region: COG4733
85569007837	Putative phage tail protein; Region: Phage-tail_3; pfam13550
85569007838	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
85569007839	Interdomain contacts; other site
85569007840	Cytokine receptor motif; other site
85569007841	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
85569007842	Fibronectin type III protein; Region: DUF3672; pfam12421
85569007843	Phage-related protein, tail component [Function unknown]; Region: COG4723
85569007844	Mpr1p, Pad1p N-terminal (MPN) domains; Region: MPN; cl13996
85569007845	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
85569007846	NlpC/P60 family; Region: NLPC_P60; cl17555
85569007847	Phage-related protein [Function unknown]; Region: gp18; COG4672
85569007848	Phage-related protein [Function unknown]; Region: COG4718
85569007849	Phage-related minor tail protein [Function unknown]; Region: COG5281
85569007850	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
85569007851	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
85569007852	Minor tail protein T; Region: Phage_tail_T; pfam06223
85569007853	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
85569007854	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
85569007855	Phage tail protein; Region: Phage_tail_3; pfam08813
85569007856	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
85569007857	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
85569007858	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
85569007859	DNA packaging protein FI; Region: Packaging_FI; pfam14000
85569007860	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
85569007861	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
85569007862	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
85569007863	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
85569007864	tandem repeat interface [polypeptide binding]; other site
85569007865	oligomer interface [polypeptide binding]; other site
85569007866	active site residues [active]
85569007867	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
85569007868	gpW; Region: gpW; pfam02831
85569007869	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
85569007870	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
85569007871	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
85569007872	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
85569007873	Predicted chitinase [General function prediction only]; Region: COG3179
85569007874	catalytic residue [active]
85569007875	Protein of unknown function (DUF754); Region: DUF754; pfam05449
85569007876	subtilase cytotoxin subunit B-like protein; Provisional; Region: PRK15265; cl14664
85569007877	Pertussis toxin, subunit 1; Region: Pertussis_S1; cl03779
85569007878	Protein of unknown function (DUF1133); Region: DUF1133; pfam06576
85569007879	Protein of unknown function (DUF968); Region: DUF968; pfam06147
85569007880	KilA-N domain; Region: KilA-N; pfam04383
85569007881	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
85569007882	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; cl05442
85569007883	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; cl05442
85569007884	PerC transcriptional activator; Region: PerC; pfam06069
85569007885	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569007886	DNA-binding site [nucleotide binding]; DNA binding site
85569007887	Ash protein family; Region: Phage_ASH; pfam10554
85569007888	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
85569007889	Predicted transcriptional regulator [Transcription]; Region: COG2932
85569007890	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569007891	non-specific DNA binding site [nucleotide binding]; other site
85569007892	salt bridge; other site
85569007893	sequence-specific DNA binding site [nucleotide binding]; other site
85569007894	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
85569007895	Catalytic site [active]
85569007896	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
85569007897	exonuclease VIII; Reviewed; Region: PRK09709
85569007898	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
85569007899	RecT family; Region: RecT; pfam03837
85569007900	Protein of unknown function (DUF4060); Region: DUF4060; pfam13269
85569007901	integrase; Provisional; Region: PRK09692
85569007902	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
85569007903	active site
85569007904	Int/Topo IB signature motif; other site
85569007905	SoxR reducing system protein RseC; Provisional; Region: PRK10862
85569007906	anti-sigma E factor; Provisional; Region: rseB; PRK09455
85569007907	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
85569007908	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
85569007909	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
85569007910	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
85569007911	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
85569007912	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
85569007913	DNA binding residues [nucleotide binding]
85569007914	L-aspartate oxidase; Provisional; Region: PRK09077
85569007915	L-aspartate oxidase; Provisional; Region: PRK06175
85569007916	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
85569007917	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
85569007918	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569007919	S-adenosylmethionine binding site [chemical binding]; other site
85569007920	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
85569007921	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
85569007922	ATP binding site [chemical binding]; other site
85569007923	Mg++ binding site [ion binding]; other site
85569007924	motif III; other site
85569007925	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
85569007926	nucleotide binding region [chemical binding]; other site
85569007927	ATP-binding site [chemical binding]; other site
85569007928	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569007929	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569007930	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
85569007931	dimerization interface [polypeptide binding]; other site
85569007932	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
85569007933	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
85569007934	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
85569007935	ligand binding site [chemical binding]; other site
85569007936	active site
85569007937	UGI interface [polypeptide binding]; other site
85569007938	catalytic site [active]
85569007939	putative methyltransferase; Provisional; Region: PRK10864
85569007940	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
85569007941	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
85569007942	thioredoxin 2; Provisional; Region: PRK10996
85569007943	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
85569007944	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
85569007945	catalytic residues [active]
85569007946	Uncharacterized conserved protein [Function unknown]; Region: COG3148
85569007947	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
85569007948	CoA binding domain; Region: CoA_binding_2; pfam13380
85569007949	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
85569007950	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
85569007951	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
85569007952	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569007953	Coenzyme A binding pocket [chemical binding]; other site
85569007954	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
85569007955	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
85569007956	domain interface [polypeptide binding]; other site
85569007957	putative active site [active]
85569007958	catalytic site [active]
85569007959	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
85569007960	domain interface [polypeptide binding]; other site
85569007961	putative active site [active]
85569007962	catalytic site [active]
85569007963	lipoprotein; Provisional; Region: PRK10759
85569007964	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
85569007965	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569007966	putative substrate translocation pore; other site
85569007967	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
85569007968	protein disaggregation chaperone; Provisional; Region: PRK10865
85569007969	Clp amino terminal domain; Region: Clp_N; pfam02861
85569007970	Clp amino terminal domain; Region: Clp_N; pfam02861
85569007971	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569007972	Walker A motif; other site
85569007973	ATP binding site [chemical binding]; other site
85569007974	Walker B motif; other site
85569007975	arginine finger; other site
85569007976	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
85569007977	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569007978	Walker A motif; other site
85569007979	ATP binding site [chemical binding]; other site
85569007980	Walker B motif; other site
85569007981	arginine finger; other site
85569007982	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
85569007983	hypothetical protein; Provisional; Region: PRK10723
85569007984	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
85569007985	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
85569007986	RNA binding surface [nucleotide binding]; other site
85569007987	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
85569007988	active site
85569007989	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
85569007990	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
85569007991	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
85569007992	30S subunit binding site; other site
85569007993	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
85569007994	Chorismate mutase type II; Region: CM_2; cl00693
85569007995	Prephenate dehydratase; Region: PDT; pfam00800
85569007996	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
85569007997	putative L-Phe binding site [chemical binding]; other site
85569007998	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
85569007999	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
85569008000	Chorismate mutase type II; Region: CM_2; cl00693
85569008001	prephenate dehydrogenase; Validated; Region: PRK08507
85569008002	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
85569008003	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
85569008004	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
85569008005	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
85569008006	metal binding site [ion binding]; metal-binding site
85569008007	active site
85569008008	I-site; other site
85569008009	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
85569008010	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
85569008011	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
85569008012	RimM N-terminal domain; Region: RimM; pfam01782
85569008013	PRC-barrel domain; Region: PRC; pfam05239
85569008014	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
85569008015	signal recognition particle protein; Provisional; Region: PRK10867
85569008016	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
85569008017	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
85569008018	P loop; other site
85569008019	GTP binding site [chemical binding]; other site
85569008020	Signal peptide binding domain; Region: SRP_SPB; pfam02978
85569008021	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
85569008022	hypothetical protein; Provisional; Region: PRK11573
85569008023	Domain of unknown function DUF21; Region: DUF21; pfam01595
85569008024	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
85569008025	Transporter associated domain; Region: CorC_HlyC; smart01091
85569008026	Uncharacterized protein conserved in bacteria (DUF2317); Region: DUF2317; cl19511
85569008027	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
85569008028	dimer interface [polypeptide binding]; other site
85569008029	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
85569008030	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
85569008031	recombination and repair protein; Provisional; Region: PRK10869
85569008032	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
85569008033	Walker A/P-loop; other site
85569008034	ATP binding site [chemical binding]; other site
85569008035	Q-loop/lid; other site
85569008036	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
85569008037	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
85569008038	ABC transporter signature motif; other site
85569008039	Walker B; other site
85569008040	D-loop; other site
85569008041	H-loop/switch region; other site
85569008042	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
85569008043	hypothetical protein; Validated; Region: PRK01777
85569008044	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
85569008045	putative coenzyme Q binding site [chemical binding]; other site
85569008046	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
85569008047	SmpB-tmRNA interface; other site
85569008048	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
85569008049	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008050	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008051	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008052	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008053	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008054	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008055	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008056	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008057	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008058	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008059	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008060	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
85569008061	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008062	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008063	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
85569008064	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008065	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008066	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
85569008067	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008068	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008069	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
85569008070	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008071	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569008072	type I secretion C-terminal target domain (VC_A0849 subclass); Region: T1SS_VCA0849; TIGR03661
85569008073	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
85569008074	Outer membrane efflux protein; Region: OEP; pfam02321
85569008075	Outer membrane efflux protein; Region: OEP; pfam02321
85569008076	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
85569008077	putative active site [active]
85569008078	type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375
85569008079	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
85569008080	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569008081	Walker A/P-loop; other site
85569008082	ATP binding site [chemical binding]; other site
85569008083	Q-loop/lid; other site
85569008084	ABC transporter signature motif; other site
85569008085	Walker B; other site
85569008086	D-loop; other site
85569008087	H-loop/switch region; other site
85569008088	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
85569008089	HlyD family secretion protein; Region: HlyD_3; pfam13437
85569008090	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
85569008091	active site
85569008092	Int/Topo IB signature motif; other site
85569008093	SEC-C motif; Region: SEC-C; pfam02810
85569008094	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
85569008095	Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG5519
85569008096	Predicted ATP-binding protein involved in virulence [General function prediction only]; Region: COG3950
85569008097	AAA domain; Region: AAA_21; pfam13304
85569008098	ABC transporter signature motif; other site
85569008099	Walker B; other site
85569008100	D-loop; other site
85569008101	H-loop/switch region; other site
85569008102	Protein of unknown function (DUF4435); Region: DUF4435; pfam14491
85569008103	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
85569008104	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569008105	non-specific DNA binding site [nucleotide binding]; other site
85569008106	salt bridge; other site
85569008107	sequence-specific DNA binding site [nucleotide binding]; other site
85569008108	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
85569008109	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; pfam03608
85569008110	Phosphotransferase system sorbitol-specific component IIA [Carbohydrate transport and metabolism]; Region: SrlB; COG3731
85569008111	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
85569008112	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
85569008113	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
85569008114	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
85569008115	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
85569008116	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
85569008117	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
85569008118	active site
85569008119	dimer interface [polypeptide binding]; other site
85569008120	magnesium binding site [ion binding]; other site
85569008121	Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with...; Region: SIS_PHI; cd05005
85569008122	tetramer interface [polypeptide binding]; other site
85569008123	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
85569008124	active site
85569008125	Glucose-6-phosphate isomerase (GPI); Region: GPI; pfam06560
85569008126	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
85569008127	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
85569008128	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
85569008129	active site turn [active]
85569008130	phosphorylation site [posttranslational modification]
85569008131	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
85569008132	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
85569008133	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
85569008134	Phage integrase, N-terminal; Region: Phage_int_SAM_2; pfam12834
85569008135	Integrase; Region: Integrase_1; pfam12835
85569008136	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
85569008137	Transposase; Region: HTH_Tnp_1; pfam01527
85569008138	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3972
85569008139	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
85569008140	Transposase; Region: HTH_Tnp_1; cl17663
85569008141	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
85569008142	Repressor of phase-1 flagellin; Region: Flag1_repress; pfam03614
85569008143	flagellin; Validated; Region: PRK08026
85569008144	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
85569008145	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
85569008146	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
85569008147	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
85569008148	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
85569008149	catalytic residues [active]
85569008150	catalytic nucleophile [active]
85569008151	Presynaptic Site I dimer interface [polypeptide binding]; other site
85569008152	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
85569008153	Synaptic Flat tetramer interface [polypeptide binding]; other site
85569008154	Synaptic Site I dimer interface [polypeptide binding]; other site
85569008155	DNA binding site [nucleotide binding]
85569008156	Helix-turn-helix domain of Hin and related proteins; Region: HTH_Hin_like; cd00569
85569008157	DNA-binding interface [nucleotide binding]; DNA binding site
85569008158	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
85569008159	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
85569008160	homodimer interface [polypeptide binding]; other site
85569008161	active site
85569008162	TDP-binding site; other site
85569008163	acceptor substrate-binding pocket; other site
85569008164	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
85569008165	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
85569008166	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569008167	Walker A/P-loop; other site
85569008168	ATP binding site [chemical binding]; other site
85569008169	Q-loop/lid; other site
85569008170	ABC transporter signature motif; other site
85569008171	Walker B; other site
85569008172	D-loop; other site
85569008173	H-loop/switch region; other site
85569008174	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
85569008175	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
85569008176	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569008177	Walker A/P-loop; other site
85569008178	ATP binding site [chemical binding]; other site
85569008179	Q-loop/lid; other site
85569008180	ABC transporter signature motif; other site
85569008181	Walker B; other site
85569008182	D-loop; other site
85569008183	H-loop/switch region; other site
85569008184	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
85569008185	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
85569008186	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819; cl19187
85569008187	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
85569008188	outer membrane receptor FepA; Provisional; Region: PRK13528
85569008189	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
85569008190	N-terminal plug; other site
85569008191	ligand-binding site [chemical binding]; other site
85569008192	secreted effector protein PipB2; Provisional; Region: PRK15196
85569008193	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
85569008194	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
85569008195	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
85569008196	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
85569008197	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
85569008198	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
85569008199	antimicrobial resistance protein Mig-14; Provisional; Region: PRK15312
85569008200	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
85569008201	Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521
85569008202	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
85569008203	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569008204	dimer interface [polypeptide binding]; other site
85569008205	phosphorylation site [posttranslational modification]
85569008206	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569008207	ATP binding site [chemical binding]; other site
85569008208	Mg2+ binding site [ion binding]; other site
85569008209	G-X-G motif; other site
85569008210	transcriptional regulatory protein TctD; Provisional; Region: PRK15479
85569008211	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569008212	active site
85569008213	phosphorylation site [posttranslational modification]
85569008214	intermolecular recognition site; other site
85569008215	dimerization interface [polypeptide binding]; other site
85569008216	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
85569008217	DNA binding site [nucleotide binding]
85569008218	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
85569008219	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
85569008220	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3333
85569008221	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
85569008222	substrate binding pocket [chemical binding]; other site
85569008223	active site
85569008224	iron coordination sites [ion binding]; other site
85569008225	hydroxyglutarate oxidase; Provisional; Region: PRK11728
85569008226	Predicted dehydrogenase [General function prediction only]; Region: COG0579
85569008227	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
85569008228	tetramerization interface [polypeptide binding]; other site
85569008229	NAD(P) binding site [chemical binding]; other site
85569008230	catalytic residues [active]
85569008231	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
85569008232	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
85569008233	inhibitor-cofactor binding pocket; inhibition site
85569008234	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569008235	catalytic residue [active]
85569008236	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
85569008237	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
85569008238	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
85569008239	helix_turn_helix gluconate operon transcriptional repressor; Region: HTH_GNTR; smart00345
85569008240	DNA-binding site [nucleotide binding]; DNA binding site
85569008241	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
85569008242	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
85569008243	bacterial OsmY and nodulation domain; Region: BON; smart00749
85569008244	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
85569008245	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
85569008246	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
85569008247	dimerization interface [polypeptide binding]; other site
85569008248	putative DNA binding site [nucleotide binding]; other site
85569008249	Transcriptional regulators [Transcription]; Region: MarR; COG1846
85569008250	putative Zn2+ binding site [ion binding]; other site
85569008251	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
85569008252	active site residue [active]
85569008253	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
85569008254	Domain in histone-like proteins of HNS family; Region: HNS; cl19571
85569008255	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
85569008256	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
85569008257	hypothetical protein; Provisional; Region: PRK10556
85569008258	hypothetical protein; Provisional; Region: PRK10132
85569008259	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
85569008260	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569008261	DNA-binding site [nucleotide binding]; DNA binding site
85569008262	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
85569008263	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569008264	homodimer interface [polypeptide binding]; other site
85569008265	catalytic residue [active]
85569008266	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
85569008267	Uncharacterized conserved protein [Function unknown]; Region: COG2128
85569008268	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
85569008269	catalytic residues [active]
85569008270	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
85569008271	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
85569008272	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
85569008273	Class I ribonucleotide reductase; Region: RNR_I; cd01679
85569008274	active site
85569008275	dimer interface [polypeptide binding]; other site
85569008276	catalytic residues [active]
85569008277	effector binding site; other site
85569008278	R2 peptide binding site; other site
85569008279	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
85569008280	dimer interface [polypeptide binding]; other site
85569008281	putative radical transfer pathway; other site
85569008282	diiron center [ion binding]; other site
85569008283	tyrosyl radical; other site
85569008284	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
85569008285	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
85569008286	Walker A/P-loop; other site
85569008287	ATP binding site [chemical binding]; other site
85569008288	Q-loop/lid; other site
85569008289	ABC transporter signature motif; other site
85569008290	Walker B; other site
85569008291	D-loop; other site
85569008292	H-loop/switch region; other site
85569008293	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
85569008294	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
85569008295	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569008296	dimer interface [polypeptide binding]; other site
85569008297	conserved gate region; other site
85569008298	putative PBP binding loops; other site
85569008299	ABC-ATPase subunit interface; other site
85569008300	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
85569008301	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
85569008302	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569008303	putative substrate translocation pore; other site
85569008304	transcriptional repressor MprA; Provisional; Region: PRK10870
85569008305	Transcriptional regulators [Transcription]; Region: MarR; COG1846
85569008306	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
85569008307	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
85569008308	HlyD family secretion protein; Region: HlyD_3; pfam13437
85569008309	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
85569008310	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569008311	putative substrate translocation pore; other site
85569008312	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
85569008313	S-ribosylhomocysteinase; Provisional; Region: PRK02260
85569008314	glutamate--cysteine ligase; Provisional; Region: PRK02107
85569008315	Predicted membrane protein [Function unknown]; Region: COG1238
85569008316	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
85569008317	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569008318	active site
85569008319	motif I; other site
85569008320	motif II; other site
85569008321	carbon storage regulator; Provisional; Region: PRK01712
85569008322	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
85569008323	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
85569008324	motif 1; other site
85569008325	active site
85569008326	motif 2; other site
85569008327	motif 3; other site
85569008328	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
85569008329	DHHA1 domain; Region: DHHA1; pfam02272
85569008330	recombination regulator RecX; Reviewed; Region: recX; PRK00117
85569008331	recombinase A; Provisional; Region: recA; PRK09354
85569008332	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
85569008333	hexamer interface [polypeptide binding]; other site
85569008334	Walker A motif; other site
85569008335	ATP binding site [chemical binding]; other site
85569008336	Walker B motif; other site
85569008337	hypothetical protein; Validated; Region: PRK03661
85569008338	murein hydrolase B; Provisional; Region: PRK10760
85569008339	lytic murein transglycosylase B; Region: MltB; TIGR02282
85569008340	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
85569008341	N-acetyl-D-glucosamine binding site [chemical binding]; other site
85569008342	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
85569008343	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
85569008344	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
85569008345	Nucleoside recognition; Region: Gate; pfam07670
85569008346	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
85569008347	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
85569008348	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
85569008349	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
85569008350	putative NAD(P) binding site [chemical binding]; other site
85569008351	active site
85569008352	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
85569008353	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
85569008354	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
85569008355	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
85569008356	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
85569008357	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
85569008358	putative active site [active]
85569008359	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
85569008360	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
85569008361	GAF domain; Region: GAF; pfam01590
85569008362	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569008363	Walker A motif; other site
85569008364	ATP binding site [chemical binding]; other site
85569008365	Walker B motif; other site
85569008366	arginine finger; other site
85569008367	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
85569008368	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
85569008369	NADPH-dependent FMN reductase; Region: FMN_red; cl00438
85569008370	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
85569008371	iron binding site [ion binding]; other site
85569008372	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
85569008373	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569008374	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
85569008375	Acylphosphatase; Region: Acylphosphatase; pfam00708
85569008376	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
85569008377	HypF finger; Region: zf-HYPF; pfam07503
85569008378	HypF finger; Region: zf-HYPF; pfam07503
85569008379	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
85569008380	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
85569008381	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569008382	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
85569008383	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
85569008384	nickel binding site [ion binding]; other site
85569008385	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
85569008386	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
85569008387	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
85569008388	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569008389	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
85569008390	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
85569008391	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
85569008392	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
85569008393	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
85569008394	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
85569008395	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
85569008396	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569008397	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569008398	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
85569008399	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
85569008400	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
85569008401	hydrogenase assembly chaperone; Provisional; Region: PRK10409
85569008402	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
85569008403	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
85569008404	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
85569008405	dimerization interface [polypeptide binding]; other site
85569008406	ATP binding site [chemical binding]; other site
85569008407	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
85569008408	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
85569008409	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
85569008410	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569008411	Walker A motif; other site
85569008412	ATP binding site [chemical binding]; other site
85569008413	Walker B motif; other site
85569008414	arginine finger; other site
85569008415	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
85569008416	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
85569008417	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
85569008418	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
85569008419	metal binding site [ion binding]; metal-binding site
85569008420	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
85569008421	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
85569008422	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
85569008423	ABC-ATPase subunit  interface; other site
85569008424	dimer interface [polypeptide binding]; other site
85569008425	putative PBP binding regions; other site
85569008426	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
85569008427	ABC-ATPase subunit  interface; other site
85569008428	dimer interface [polypeptide binding]; other site
85569008429	putative PBP binding regions; other site
85569008430	effector protein YopJ; Provisional; Region: PRK15371
85569008431	transcriptional activator SprB; Provisional; Region: PRK15320
85569008432	transcriptional regulator SirC; Provisional; Region: PRK15044
85569008433	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569008434	putative type III secretion system effector protein OrgC; Provisional; Region: PRK15321
85569008435	invasion protein OrgB; Provisional; Region: PRK15322
85569008436	invasion protein OrgA; Provisional; Region: PRK15323
85569008437	type III secretion system lipoprotein PrgK; Provisional; Region: PRK15324
85569008438	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
85569008439	type III secretion system needle complex protein PrgI; Provisional; Region: PRK15326
85569008440	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327
85569008441	transcriptional regulator HilD; Provisional; Region: PRK15185
85569008442	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569008443	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569008444	invasion protein regulator; Provisional; Region: PRK12370
85569008445	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
85569008446	DNA binding site [nucleotide binding]
85569008447	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
85569008448	binding surface
85569008449	TPR motif; other site
85569008450	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
85569008451	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
85569008452	N-acetyl-D-glucosamine binding site [chemical binding]; other site
85569008453	catalytic residue [active]
85569008454	pathogenicity island 1 effector protein StpP; Provisional; Region: PRK15375
85569008455	SicP binding; Region: SicP-binding; pfam09119
85569008456	GTPase-activating protein (GAP) domain found in bacterial cytotoxins, ExoS, SptP, and YopE. Part of protein secretion system; stimulates Rac1- dependent cytoskeletal changes that promote bacterial internalization; Region: ToxGAP; cd00219
85569008457	switch II binding region; other site
85569008458	Rac1 P-loop interaction site [polypeptide binding]; other site
85569008459	GTP binding residues [chemical binding]; other site
85569008460	switch I binding region; other site
85569008461	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cd00047
85569008462	active site
85569008463	chaperone protein SicP; Provisional; Region: PRK15329
85569008464	putative acyl carrier protein IacP; Validated; Region: PRK08172
85569008465	pathogenicity island 1 effector protein SipA; Provisional; Region: PRK15376
85569008466	cell invasion protein SipD; Provisional; Region: PRK15330
85569008467	pathogenicity island 1 effector protein SipC; Provisional; Region: PRK15373
85569008468	pathogenicity island 1 effector protein SipB; Provisional; Region: PRK15374
85569008469	Secretion system effector C (SseC) like family; Region: SseC; pfam04888
85569008470	chaperone protein SicA; Provisional; Region: PRK15331
85569008471	Tetratricopeptide repeat; Region: TPR_3; pfam07720
85569008472	Tetratricopeptide repeat; Region: TPR_3; pfam07720
85569008473	type III secretion system protein SpaS; Validated; Region: PRK08156
85569008474	type III secretion system protein SpaR; Provisional; Region: PRK15332
85569008475	type III secretion system protein SpaQ; Provisional; Region: PRK15333
85569008476	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
85569008477	type III secretion system protein SpaO; Validated; Region: PRK08158
85569008478	type III secretion system apparatus protein YscQ/HrcQ; Region: SpaO_YscQ; TIGR02551
85569008479	Surface presentation of antigens protein; Region: SPAN; cl19597
85569008480	Salmonella surface presentation of antigen gene type M protein; Region: SPAM; pfam02090
85569008481	ATP synthase SpaL; Validated; Region: PRK08149
85569008482	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
85569008483	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
85569008484	Walker A motif; other site
85569008485	ATP binding site [chemical binding]; other site
85569008486	Walker B motif; other site
85569008487	type III secretion system chaperone SpaK; Provisional; Region: PRK15336
85569008488	type III secretion system protein InvA; Provisional; Region: PRK15337
85569008489	type III secretion system regulator InvE; Provisional; Region: PRK15338
85569008490	type III secretion regulator YopN/LcrE/InvE/MxiC; Region: LcrE; TIGR02568
85569008491	type III secretion system outer membrane pore InvG; Provisional; Region: PRK15339
85569008492	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
85569008493	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
85569008494	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
85569008495	transcriptional regulator InvF; Provisional; Region: PRK15340
85569008496	InvH outer membrane lipoprotein; Region: InvH; pfam04741
85569008497	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
85569008498	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
85569008499	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
85569008500	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
85569008501	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
85569008502	active site
85569008503	metal binding site [ion binding]; metal-binding site
85569008504	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
85569008505	MutS domain I; Region: MutS_I; pfam01624
85569008506	MutS domain II; Region: MutS_II; pfam05188
85569008507	MutS domain III; Region: MutS_III; pfam05192
85569008508	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
85569008509	Walker A/P-loop; other site
85569008510	ATP binding site [chemical binding]; other site
85569008511	Q-loop/lid; other site
85569008512	ABC transporter signature motif; other site
85569008513	Walker B; other site
85569008514	D-loop; other site
85569008515	H-loop/switch region; other site
85569008516	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460
85569008517	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569008518	Major Facilitator Superfamily; Region: MFS_1; pfam07690
85569008519	putative substrate translocation pore; other site
85569008520	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569008521	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569008522	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
85569008523	putative effector binding pocket; other site
85569008524	dimerization interface [polypeptide binding]; other site
85569008525	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
85569008526	GntP family permease; Region: GntP_permease; pfam02447
85569008527	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
85569008528	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
85569008529	putative NAD(P) binding site [chemical binding]; other site
85569008530	active site
85569008531	putative substrate binding site [chemical binding]; other site
85569008532	Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; Region: Hfi; COG3622
85569008533	hypothetical protein; Provisional; Region: PRK09989
85569008534	putative aldolase; Validated; Region: PRK08130
85569008535	intersubunit interface [polypeptide binding]; other site
85569008536	active site
85569008537	Zn2+ binding site [ion binding]; other site
85569008538	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
85569008539	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
85569008540	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
85569008541	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833
85569008542	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
85569008543	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
85569008544	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
85569008545	Transcriptional regulators [Transcription]; Region: MarR; COG1846
85569008546	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
85569008547	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
85569008548	3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases [Coenzyme metabolism]; Region: UbiD; COG0043
85569008549	Protein of unknown function (DUF1062); Region: DUF1062; cl01786
85569008550	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
85569008551	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
85569008552	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
85569008553	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
85569008554	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
85569008555	DNA binding residues [nucleotide binding]
85569008556	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
85569008557	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
85569008558	Peptidase family M23; Region: Peptidase_M23; pfam01551
85569008559	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569008560	S-adenosylmethionine binding site [chemical binding]; other site
85569008561	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
85569008562	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
85569008563	Permutation of conserved domain; other site
85569008564	active site
85569008565	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
85569008566	homotrimer interaction site [polypeptide binding]; other site
85569008567	zinc binding site [ion binding]; other site
85569008568	CDP-binding sites; other site
85569008569	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
85569008570	substrate binding site; other site
85569008571	dimer interface; other site
85569008572	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
85569008573	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
85569008574	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
85569008575	ligand-binding site [chemical binding]; other site
85569008576	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
85569008577	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
85569008578	CysD dimerization site [polypeptide binding]; other site
85569008579	G1 box; other site
85569008580	putative GEF interaction site [polypeptide binding]; other site
85569008581	GTP/Mg2+ binding site [chemical binding]; other site
85569008582	Switch I region; other site
85569008583	G2 box; other site
85569008584	G3 box; other site
85569008585	Switch II region; other site
85569008586	G4 box; other site
85569008587	G5 box; other site
85569008588	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
85569008589	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
85569008590	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
85569008591	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
85569008592	Active Sites [active]
85569008593	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
85569008594	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
85569008595	metal binding site [ion binding]; metal-binding site
85569008596	putative ssRNA endonuclease; Provisional; Region: PRK11558
85569008597	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
85569008598	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09727
85569008599	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
85569008600	CT1975-like protein; Region: Cas_CT1975; pfam09344
85569008601	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09731
85569008602	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
85569008603	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
85569008604	CRISPR-associated helicase Cas3 [Defense mechanisms]; Region: COG1203
85569008605	CRISPR/Cas system-associated protein Cas3; Region: Cas3_I; cd09639
85569008606	pathogenicity island 1 effector protein SopD; Provisional; Region: PRK15379
85569008607	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
85569008608	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
85569008609	Active Sites [active]
85569008610	sulfite reductase subunit beta; Provisional; Region: PRK13504
85569008611	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
85569008612	Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077
85569008613	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
85569008614	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569008615	Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369
85569008616	Flavodoxin; Region: Flavodoxin_1; pfam00258
85569008617	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
85569008618	FAD binding pocket [chemical binding]; other site
85569008619	FAD binding motif [chemical binding]; other site
85569008620	catalytic residues [active]
85569008621	NAD binding pocket [chemical binding]; other site
85569008622	phosphate binding motif [ion binding]; other site
85569008623	beta-alpha-beta structure motif; other site
85569008624	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
85569008625	active site
85569008626	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
85569008627	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
85569008628	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
85569008629	enolase; Provisional; Region: eno; PRK00077
85569008630	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
85569008631	dimer interface [polypeptide binding]; other site
85569008632	metal binding site [ion binding]; metal-binding site
85569008633	substrate binding pocket [chemical binding]; other site
85569008634	CTP synthetase; Validated; Region: pyrG; PRK05380
85569008635	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
85569008636	Catalytic site [active]
85569008637	active site
85569008638	UTP binding site [chemical binding]; other site
85569008639	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
85569008640	active site
85569008641	putative oxyanion hole; other site
85569008642	catalytic triad [active]
85569008643	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
85569008644	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
85569008645	homodimer interface [polypeptide binding]; other site
85569008646	metal binding site [ion binding]; metal-binding site
85569008647	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
85569008648	homodimer interface [polypeptide binding]; other site
85569008649	active site
85569008650	putative chemical substrate binding site [chemical binding]; other site
85569008651	metal binding site [ion binding]; metal-binding site
85569008652	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain [Transcription]; Region: COG3609
85569008653	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
85569008654	HD domain; Region: HD_4; pfam13328
85569008655	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
85569008656	synthetase active site [active]
85569008657	NTP binding site [chemical binding]; other site
85569008658	metal binding site [ion binding]; metal-binding site
85569008659	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
85569008660	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
85569008661	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
85569008662	TRAM domain; Region: TRAM; pfam01938
85569008663	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569008664	S-adenosylmethionine binding site [chemical binding]; other site
85569008665	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
85569008666	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
85569008667	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569008668	dimerization interface [polypeptide binding]; other site
85569008669	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569008670	dimer interface [polypeptide binding]; other site
85569008671	phosphorylation site [posttranslational modification]
85569008672	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569008673	ATP binding site [chemical binding]; other site
85569008674	Mg2+ binding site [ion binding]; other site
85569008675	G-X-G motif; other site
85569008676	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
85569008677	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569008678	active site
85569008679	phosphorylation site [posttranslational modification]
85569008680	intermolecular recognition site; other site
85569008681	dimerization interface [polypeptide binding]; other site
85569008682	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
85569008683	putative binding surface; other site
85569008684	active site
85569008685	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
85569008686	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
85569008687	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
85569008688	active site
85569008689	tetramer interface [polypeptide binding]; other site
85569008690	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
85569008691	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
85569008692	active site
85569008693	tetramer interface [polypeptide binding]; other site
85569008694	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569008695	D-galactonate transporter; Region: 2A0114; TIGR00893
85569008696	putative substrate translocation pore; other site
85569008697	flavodoxin; Provisional; Region: PRK08105
85569008698	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
85569008699	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
85569008700	probable active site [active]
85569008701	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
85569008702	SecY interacting protein Syd; Provisional; Region: PRK04968
85569008703	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
85569008704	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
85569008705	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
85569008706	Domain of unknown function (DUF4478); Region: DUF4478; pfam14793
85569008707	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
85569008708	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
85569008709	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
85569008710	serine transporter; Region: stp; TIGR00814
85569008711	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
85569008712	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
85569008713	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
85569008714	flap endonuclease-like protein; Provisional; Region: PRK09482
85569008715	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
85569008716	active site
85569008717	metal binding site 1 [ion binding]; metal-binding site
85569008718	putative 5' ssDNA interaction site; other site
85569008719	metal binding site 3; metal-binding site
85569008720	metal binding site 2 [ion binding]; metal-binding site
85569008721	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
85569008722	putative DNA binding site [nucleotide binding]; other site
85569008723	putative metal binding site [ion binding]; other site
85569008724	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
85569008725	dimer interface [polypeptide binding]; other site
85569008726	active site
85569008727	metal binding site [ion binding]; metal-binding site
85569008728	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
85569008729	intersubunit interface [polypeptide binding]; other site
85569008730	active site
85569008731	Zn2+ binding site [ion binding]; other site
85569008732	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
85569008733	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569008734	putative substrate translocation pore; other site
85569008735	L-fucose isomerase; Provisional; Region: fucI; PRK10991
85569008736	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
85569008737	hexamer (dimer of trimers) interface [polypeptide binding]; other site
85569008738	trimer interface [polypeptide binding]; other site
85569008739	substrate binding site [chemical binding]; other site
85569008740	Mn binding site [ion binding]; other site
85569008741	L-fuculokinase; Provisional; Region: PRK10331
85569008742	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
85569008743	nucleotide binding site [chemical binding]; other site
85569008744	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
85569008745	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
85569008746	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
85569008747	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
85569008748	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
85569008749	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
85569008750	hypothetical protein; Provisional; Region: PRK10873
85569008751	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
85569008752	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569008753	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
85569008754	dimerization interface [polypeptide binding]; other site
85569008755	substrate binding pocket [chemical binding]; other site
85569008756	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
85569008757	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
85569008758	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
85569008759	catalytic residue [active]
85569008760	CsdA-binding activator; Provisional; Region: PRK15019
85569008761	Predicted permeases [General function prediction only]; Region: RarD; COG2962
85569008762	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
85569008763	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
85569008764	putative ATP binding site [chemical binding]; other site
85569008765	putative substrate interface [chemical binding]; other site
85569008766	murein transglycosylase A; Provisional; Region: mltA; PRK11162
85569008767	MltA specific insert domain; Region: MltA; smart00925
85569008768	3D domain; Region: 3D; pfam06725
85569008769	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
85569008770	AMIN domain; Region: AMIN; pfam11741
85569008771	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
85569008772	active site
85569008773	metal binding site [ion binding]; metal-binding site
85569008774	N-acetylglutamate synthase; Validated; Region: PRK05279
85569008775	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
85569008776	putative feedback inhibition sensing region; other site
85569008777	putative nucleotide binding site [chemical binding]; other site
85569008778	putative substrate binding site [chemical binding]; other site
85569008779	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569008780	Coenzyme A binding pocket [chemical binding]; other site
85569008781	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
85569008782	AAA domain; Region: AAA_30; pfam13604
85569008783	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
85569008784	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
85569008785	Protein of unknown function (DUF770); Region: DUF770; cl01402
85569008786	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
85569008787	protease3; Provisional; Region: PRK15101
85569008788	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
85569008789	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
85569008790	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
85569008791	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
85569008792	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
85569008793	hypothetical protein; Provisional; Region: PRK10332
85569008794	Tfp pilus assembly protein PilV [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilV; COG4967
85569008795	hypothetical protein; Provisional; Region: PRK11521
85569008796	hypothetical protein; Provisional; Region: PRK10557
85569008797	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
85569008798	hypothetical protein; Provisional; Region: PRK10506
85569008799	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
85569008800	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
85569008801	dimerization interface [polypeptide binding]; other site
85569008802	active site
85569008803	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
85569008804	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
85569008805	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
85569008806	PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524
85569008807	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
85569008808	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
85569008809	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
85569008810	putative active site [active]
85569008811	Ap4A binding site [chemical binding]; other site
85569008812	nudix motif; other site
85569008813	putative metal binding site [ion binding]; other site
85569008814	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
85569008815	putative DNA-binding cleft [nucleotide binding]; other site
85569008816	putative DNA clevage site; other site
85569008817	molecular lever; other site
85569008818	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
85569008819	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
85569008820	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
85569008821	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
85569008822	active site
85569008823	catalytic tetrad [active]
85569008824	lysophospholipid transporter LplT; Provisional; Region: PRK11195
85569008825	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569008826	putative substrate translocation pore; other site
85569008827	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
85569008828	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
85569008829	putative acyl-acceptor binding pocket; other site
85569008830	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
85569008831	acyl-activating enzyme (AAE) consensus motif; other site
85569008832	putative AMP binding site [chemical binding]; other site
85569008833	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
85569008834	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
85569008835	DNA binding site [nucleotide binding]
85569008836	domain linker motif; other site
85569008837	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
85569008838	dimerization interface (closed form) [polypeptide binding]; other site
85569008839	ligand binding site [chemical binding]; other site
85569008840	Transcriptional regulators [Transcription]; Region: PurR; COG1609
85569008841	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
85569008842	DNA binding site [nucleotide binding]
85569008843	domain linker motif; other site
85569008844	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
85569008845	dimerization interface (closed form) [polypeptide binding]; other site
85569008846	ligand binding site [chemical binding]; other site
85569008847	diaminopimelate decarboxylase; Provisional; Region: PRK11165
85569008848	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
85569008849	active site
85569008850	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
85569008851	substrate binding site [chemical binding]; other site
85569008852	catalytic residues [active]
85569008853	dimer interface [polypeptide binding]; other site
85569008854	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
85569008855	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569008856	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
85569008857	dimerization interface [polypeptide binding]; other site
85569008858	putative racemase; Provisional; Region: PRK10200
85569008859	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
85569008860	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569008861	putative substrate translocation pore; other site
85569008862	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
85569008863	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
85569008864	NADP binding site [chemical binding]; other site
85569008865	homodimer interface [polypeptide binding]; other site
85569008866	active site
85569008867	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
85569008868	putative acyltransferase; Provisional; Region: PRK05790
85569008869	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
85569008870	dimer interface [polypeptide binding]; other site
85569008871	active site
85569008872	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569008873	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569008874	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
85569008875	dimerization interface [polypeptide binding]; other site
85569008876	Predicted membrane protein [Function unknown]; Region: COG4125
85569008877	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
85569008878	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
85569008879	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
85569008880	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
85569008881	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
85569008882	putative metal binding site [ion binding]; other site
85569008883	putative homodimer interface [polypeptide binding]; other site
85569008884	putative homotetramer interface [polypeptide binding]; other site
85569008885	putative homodimer-homodimer interface [polypeptide binding]; other site
85569008886	putative allosteric switch controlling residues; other site
85569008887	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
85569008888	transcriptional activator SprB; Provisional; Region: PRK15320
85569008889	Protein of unknown function (DUF1401); Region: DUF1401; pfam07180
85569008890	Fimbrial protein; Region: Fimbrial; pfam00419
85569008891	fimbrial chaperone protein StdC; Provisional; Region: PRK15254
85569008892	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
85569008893	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
85569008894	fimbrial outer membrane usher protein StdB; Provisional; Region: PRK15255
85569008895	PapC N-terminal domain; Region: PapC_N; pfam13954
85569008896	Outer membrane usher protein; Region: Usher; pfam00577
85569008897	PapC C-terminal domain; Region: PapC_C; pfam13953
85569008898	fimbrial protein StdA; Provisional; Region: PRK15210
85569008899	hypothetical protein; Provisional; Region: PRK10316
85569008900	YfdX protein; Region: YfdX; pfam10938
85569008901	Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane]; Region: COG3637
85569008902	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
85569008903	oligomeric interface; other site
85569008904	putative active site [active]
85569008905	homodimer interface [polypeptide binding]; other site
85569008906	Virulence-associated protein and related proteins [Function unknown]; Region: VagC; COG4456
85569008907	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
85569008908	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
85569008909	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
85569008910	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
85569008911	Peptidase family M23; Region: Peptidase_M23; pfam01551
85569008912	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
85569008913	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
85569008914	active site
85569008915	metal binding site [ion binding]; metal-binding site
85569008916	nudix motif; other site
85569008917	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
85569008918	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
85569008919	dimer interface [polypeptide binding]; other site
85569008920	putative anticodon binding site; other site
85569008921	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
85569008922	motif 1; other site
85569008923	active site
85569008924	motif 2; other site
85569008925	motif 3; other site
85569008926	peptide chain release factor 2; Provisional; Region: PRK08787
85569008927	This domain is found in peptide chain release factors; Region: PCRF; smart00937
85569008928	RF-1 domain; Region: RF-1; pfam00472
85569008929	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
85569008930	DHH family; Region: DHH; pfam01368
85569008931	DHHA1 domain; Region: DHHA1; pfam02272
85569008932	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
85569008933	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
85569008934	dimerization domain [polypeptide binding]; other site
85569008935	dimer interface [polypeptide binding]; other site
85569008936	catalytic residues [active]
85569008937	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
85569008938	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
85569008939	active site
85569008940	Int/Topo IB signature motif; other site
85569008941	flavodoxin FldB; Provisional; Region: PRK12359
85569008942	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
85569008943	hypothetical protein; Provisional; Region: PRK10878
85569008944	putative global regulator; Reviewed; Region: PRK09559
85569008945	Aminomethyltransferase folate-binding domain; Region: GCV_T; pfam01571
85569008946	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
85569008947	hemolysin; Provisional; Region: PRK15087
85569008948	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
85569008949	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
85569008950	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
85569008951	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; pfam13557
85569008952	glycine dehydrogenase; Provisional; Region: PRK05367
85569008953	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
85569008954	tetramer interface [polypeptide binding]; other site
85569008955	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569008956	catalytic residue [active]
85569008957	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
85569008958	tetramer interface [polypeptide binding]; other site
85569008959	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569008960	catalytic residue [active]
85569008961	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
85569008962	lipoyl attachment site [posttranslational modification]; other site
85569008963	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
85569008964	Aminomethyltransferase folate-binding domain; Region: GCV_T; pfam01571
85569008965	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
85569008966	oxidoreductase; Provisional; Region: PRK08013
85569008967	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
85569008968	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
85569008969	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
85569008970	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
85569008971	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
85569008972	active site
85569008973	hypothetical protein; Reviewed; Region: PRK01736
85569008974	Z-ring-associated protein; Provisional; Region: PRK10972
85569008975	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; cl00360
85569008976	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
85569008977	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
85569008978	ligand binding site [chemical binding]; other site
85569008979	NAD binding site [chemical binding]; other site
85569008980	tetramer interface [polypeptide binding]; other site
85569008981	catalytic site [active]
85569008982	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
85569008983	L-serine binding site [chemical binding]; other site
85569008984	ACT domain interface; other site
85569008985	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
85569008986	tetramer (dimer of dimers) interface [polypeptide binding]; other site
85569008987	active site
85569008988	dimer interface [polypeptide binding]; other site
85569008989	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
85569008990	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569008991	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
85569008992	putative dimerization interface [polypeptide binding]; other site
85569008993	oxidative stress defense protein; Provisional; Region: PRK11087
85569008994	arginine exporter protein; Provisional; Region: PRK09304
85569008995	mechanosensitive channel MscS; Provisional; Region: PRK10334
85569008996	Mechanosensitive ion channel; Region: MS_channel; pfam00924
85569008997	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
85569008998	active site
85569008999	intersubunit interface [polypeptide binding]; other site
85569009000	zinc binding site [ion binding]; other site
85569009001	Na+ binding site [ion binding]; other site
85569009002	phosphoglycerate kinase; Provisional; Region: pgk; PRK00073
85569009003	substrate binding site [chemical binding]; other site
85569009004	hinge regions; other site
85569009005	ADP binding site [chemical binding]; other site
85569009006	catalytic site [active]
85569009007	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
85569009008	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
85569009009	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
85569009010	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
85569009011	trimer interface [polypeptide binding]; other site
85569009012	putative Zn binding site [ion binding]; other site
85569009013	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
85569009014	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
85569009015	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
85569009016	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
85569009017	Walker A/P-loop; other site
85569009018	ATP binding site [chemical binding]; other site
85569009019	Q-loop/lid; other site
85569009020	ABC transporter signature motif; other site
85569009021	Walker B; other site
85569009022	D-loop; other site
85569009023	H-loop/switch region; other site
85569009024	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
85569009025	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
85569009026	Walker A/P-loop; other site
85569009027	ATP binding site [chemical binding]; other site
85569009028	Q-loop/lid; other site
85569009029	ABC transporter signature motif; other site
85569009030	Walker B; other site
85569009031	D-loop; other site
85569009032	H-loop/switch region; other site
85569009033	transketolase; Reviewed; Region: PRK12753
85569009034	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
85569009035	TPP-binding site [chemical binding]; other site
85569009036	dimer interface [polypeptide binding]; other site
85569009037	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
85569009038	PYR/PP interface [polypeptide binding]; other site
85569009039	dimer interface [polypeptide binding]; other site
85569009040	TPP binding site [chemical binding]; other site
85569009041	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
85569009042	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
85569009043	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
85569009044	oligomer interface [polypeptide binding]; other site
85569009045	putative active site [active]
85569009046	Mn binding site [ion binding]; other site
85569009047	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
85569009048	Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055
85569009049	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
85569009050	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
85569009051	putative NAD(P) binding site [chemical binding]; other site
85569009052	catalytic Zn binding site [ion binding]; other site
85569009053	structural Zn binding site [ion binding]; other site
85569009054	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
85569009055	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
85569009056	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
85569009057	Transcriptional regulators [Transcription]; Region: FadR; COG2186
85569009058	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569009059	DNA-binding site [nucleotide binding]; DNA binding site
85569009060	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
85569009061	DNA phosphorothioation-dependent restriction protein DptH; Region: dnd_assoc_2; TIGR03237
85569009062	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
85569009063	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
85569009064	dimer interface [polypeptide binding]; other site
85569009065	active site
85569009066	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
85569009067	catalytic residues [active]
85569009068	substrate binding site [chemical binding]; other site
85569009069	Virulence promoting factor; Region: YqgB; pfam11036
85569009070	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
85569009071	S-adenosylmethionine synthetase; Validated; Region: PRK05250
85569009072	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
85569009073	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
85569009074	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
85569009075	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
85569009076	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569009077	putative substrate translocation pore; other site
85569009078	hypothetical protein; Provisional; Region: PRK04860
85569009079	DNA-specific endonuclease I; Provisional; Region: PRK15137
85569009080	RNA methyltransferase, RsmE family; Region: TIGR00046
85569009081	glutathione synthetase; Provisional; Region: PRK05246
85569009082	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
85569009083	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
85569009084	hypothetical protein; Validated; Region: PRK00228
85569009085	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
85569009086	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
85569009087	Transcriptional regulator [Transcription]; Region: IclR; COG1414
85569009088	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
85569009089	Walker A motif; other site
85569009090	ATP binding site [chemical binding]; other site
85569009091	Walker B motif; other site
85569009092	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
85569009093	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
85569009094	catalytic residue [active]
85569009095	YGGT family; Region: YGGT; pfam02325
85569009096	Predicted integral membrane protein [Function unknown]; Region: COG0762
85569009097	hypothetical protein; Validated; Region: PRK05090
85569009098	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
85569009099	active site
85569009100	dimerization interface [polypeptide binding]; other site
85569009101	HemN family oxidoreductase; Provisional; Region: PRK05660
85569009102	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569009103	FeS/SAM binding site; other site
85569009104	HemN C-terminal domain; Region: HemN_C; pfam06969
85569009105	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
85569009106	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
85569009107	active site
85569009108	homodimer interface [polypeptide binding]; other site
85569009109	hypothetical protein; Provisional; Region: PRK10626
85569009110	hypothetical protein; Provisional; Region: PRK11702
85569009111	Predicted S-adenosylmethionine-dependent methyltransferase [General function prediction only]; Region: COG0220
85569009112	adenine DNA glycosylase; Provisional; Region: PRK10880
85569009113	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
85569009114	minor groove reading motif; other site
85569009115	helix-hairpin-helix signature motif; other site
85569009116	substrate binding pocket [chemical binding]; other site
85569009117	active site
85569009118	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
85569009119	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
85569009120	DNA binding and oxoG recognition site [nucleotide binding]
85569009121	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2924
85569009122	murein transglycosylase C; Provisional; Region: mltC; PRK11671
85569009123	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
85569009124	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
85569009125	N-acetyl-D-glucosamine binding site [chemical binding]; other site
85569009126	catalytic residue [active]
85569009127	ornithine decarboxylase; Provisional; Region: PRK13578
85569009128	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
85569009129	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
85569009130	homodimer interface [polypeptide binding]; other site
85569009131	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569009132	catalytic residue [active]
85569009133	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
85569009134	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
85569009135	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253
85569009136	dimer interface [polypeptide binding]; other site
85569009137	metal binding site [ion binding]; metal-binding site
85569009138	Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427
85569009139	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
85569009140	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
85569009141	FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2  has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal...; Region: FkbR2; cd03451
85569009142	putative active site [active]
85569009143	putative catalytic site [active]
85569009144	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
85569009145	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
85569009146	putative dimerization interface [polypeptide binding]; other site
85569009147	putative substrate binding pocket [chemical binding]; other site
85569009148	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
85569009149	Sulfatase; Region: Sulfatase; pfam00884
85569009150	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
85569009151	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569009152	FeS/SAM binding site; other site
85569009153	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
85569009154	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
85569009155	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569009156	DNA binding residues [nucleotide binding]
85569009157	dimerization interface [polypeptide binding]; other site
85569009158	Protein of unknown function (DUF3156); Region: DUF3156; pfam11354
85569009159	Amino acid permease; Region: AA_permease_2; pfam13520
85569009160	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
85569009161	Predicted enzyme of the cupin superfamily [General function prediction only]; Region: COG3450
85569009162	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
85569009163	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
85569009164	Escherichia coli NAD+-dependent phenylacetaldehyde dehydrogenase PadA-like; Region: ALDH_PADH_NahF; cd07113
85569009165	NAD(P) binding site [chemical binding]; other site
85569009166	catalytic residues [active]
85569009167	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
85569009168	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
85569009169	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
85569009170	active site
85569009171	catalytic site [active]
85569009172	Zn binding site [ion binding]; other site
85569009173	tetramer interface [polypeptide binding]; other site
85569009174	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
85569009175	putative active site [active]
85569009176	catalytic triad [active]
85569009177	putative dimer interface [polypeptide binding]; other site
85569009178	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569009179	D-galactonate transporter; Region: 2A0114; TIGR00893
85569009180	putative substrate translocation pore; other site
85569009181	mannonate dehydratase; Provisional; Region: PRK03906
85569009182	mannonate dehydratase; Region: uxuA; TIGR00695
85569009183	D-mannonate oxidoreductase; Provisional; Region: PRK15037
85569009184	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
85569009185	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
85569009186	glucuronate isomerase; Reviewed; Region: PRK02925
85569009187	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cl19050
85569009188	dimer interface [polypeptide binding]; other site
85569009189	putative CheW interface [polypeptide binding]; other site
85569009190	Chemoreceptor zinc-binding domain; Region: CZB; pfam13682
85569009191	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
85569009192	CHAP domain; Region: CHAP; pfam05257
85569009193	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
85569009194	putative S-transferase; Provisional; Region: PRK11752
85569009195	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
85569009196	C-terminal domain interface [polypeptide binding]; other site
85569009197	GSH binding site (G-site) [chemical binding]; other site
85569009198	dimer interface [polypeptide binding]; other site
85569009199	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
85569009200	dimer interface [polypeptide binding]; other site
85569009201	N-terminal domain interface [polypeptide binding]; other site
85569009202	active site
85569009203	molybdate ABC transporter periplasmic molybdate-binding protein; Provisional; Region: PRK03537
85569009204	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
85569009205	putative ligand binding residues [chemical binding]; other site
85569009206	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
85569009207	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
85569009208	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
85569009209	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
85569009210	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
85569009211	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
85569009212	putative substrate-binding site; other site
85569009213	nickel binding site [ion binding]; other site
85569009214	hydrogenase 2 large subunit; Provisional; Region: PRK10467
85569009215	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
85569009216	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
85569009217	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
85569009218	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
85569009219	hydrogenase 2 small subunit; Provisional; Region: PRK10468
85569009220	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
85569009221	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
85569009222	NiFe/NiFeSe hydrogenase small subunit C-terminal; Region: NiFe_hyd_SSU_C; pfam14720
85569009223	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
85569009224	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
85569009225	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569009226	dimerization interface [polypeptide binding]; other site
85569009227	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
85569009228	dimer interface [polypeptide binding]; other site
85569009229	putative CheW interface [polypeptide binding]; other site
85569009230	hypothetical protein; Provisional; Region: PRK05208
85569009231	oxidoreductase; Provisional; Region: PRK07985
85569009232	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
85569009233	NAD binding site [chemical binding]; other site
85569009234	metal binding site [ion binding]; metal-binding site
85569009235	active site
85569009236	biopolymer transport protein ExbD; Provisional; Region: PRK11267
85569009237	biopolymer transport protein ExbB; Provisional; Region: PRK10414
85569009238	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
85569009239	homodimer interface [polypeptide binding]; other site
85569009240	substrate-cofactor binding pocket; other site
85569009241	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569009242	catalytic residue [active]
85569009243	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
85569009244	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
85569009245	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
85569009246	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569009247	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569009248	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
85569009249	dimer interface [polypeptide binding]; other site
85569009250	active site
85569009251	metal binding site [ion binding]; metal-binding site
85569009252	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
85569009253	active site
85569009254	catalytic tetrad [active]
85569009255	anion transporter; Region: dass; TIGR00785
85569009256	Sodium:sulfate symporter transmembrane region; Region: Na_sulph_symp; pfam00939
85569009257	transmembrane helices; other site
85569009258	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
85569009259	nucleotide binding site/active site [active]
85569009260	catalytic residue [active]
85569009261	hypothetical protein; Provisional; Region: PRK01254
85569009262	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
85569009263	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
85569009264	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
85569009265	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
85569009266	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
85569009267	DctM-like transporters; Region: DctM; pfam06808
85569009268	TRAP transporter, DctM subunit; Region: dctM; TIGR00786
85569009269	FtsI repressor; Provisional; Region: PRK10883
85569009270	Sulfur oxidation protein SoxY; Region: SoxY; cl19207
85569009271	The first Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_1_CueO_FtsP; cd04232
85569009272	Domain 2 interface [polypeptide binding]; other site
85569009273	Domain 3 interface [polypeptide binding]; other site
85569009274	trinuclear Cu binding site [ion binding]; other site
85569009275	The second Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_2_CueO_FtsP; cd13867
85569009276	Domain 1 interface [polypeptide binding]; other site
85569009277	Domain 3 interface [polypeptide binding]; other site
85569009278	The third Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_3_CueO_FtsP; cd13890
85569009279	Domain 2 interface [polypeptide binding]; other site
85569009280	Domain 1 interface [polypeptide binding]; other site
85569009281	Type 1 (T1) Cu binding site [ion binding]; other site
85569009282	trinuclear Cu binding site [ion binding]; other site
85569009283	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
85569009284	putative acyl-acceptor binding pocket; other site
85569009285	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
85569009286	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
85569009287	CAP-like domain; other site
85569009288	active site
85569009289	primary dimer interface [polypeptide binding]; other site
85569009290	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
85569009291	Helix-turn-helix domain; Region: HTH_18; pfam12833
85569009292	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569009293	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
85569009294	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
85569009295	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
85569009296	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569009297	active site
85569009298	phosphorylation site [posttranslational modification]
85569009299	intermolecular recognition site; other site
85569009300	dimerization interface [polypeptide binding]; other site
85569009301	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
85569009302	DNA binding site [nucleotide binding]
85569009303	sensor protein QseC; Provisional; Region: PRK10337
85569009304	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569009305	dimer interface [polypeptide binding]; other site
85569009306	phosphorylation site [posttranslational modification]
85569009307	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569009308	ATP binding site [chemical binding]; other site
85569009309	Mg2+ binding site [ion binding]; other site
85569009310	G-X-G motif; other site
85569009311	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
85569009312	Uncharacterized conserved protein [Function unknown]; Region: COG1359
85569009313	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
85569009314	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569009315	ATP binding site [chemical binding]; other site
85569009316	Mg2+ binding site [ion binding]; other site
85569009317	G-X-G motif; other site
85569009318	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
85569009319	anchoring element; other site
85569009320	dimer interface [polypeptide binding]; other site
85569009321	ATP binding site [chemical binding]; other site
85569009322	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
85569009323	active site
85569009324	metal binding site [ion binding]; metal-binding site
85569009325	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
85569009326	esterase YqiA; Provisional; Region: PRK11071
85569009327	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
85569009328	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
85569009329	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
85569009330	active site
85569009331	metal binding site [ion binding]; metal-binding site
85569009332	hexamer interface [polypeptide binding]; other site
85569009333	putative dehydrogenase; Provisional; Region: PRK11039
85569009334	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
85569009335	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
85569009336	dimer interface [polypeptide binding]; other site
85569009337	ADP-ribose binding site [chemical binding]; other site
85569009338	active site
85569009339	nudix motif; other site
85569009340	metal binding site [ion binding]; metal-binding site
85569009341	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
85569009342	hypothetical protein; Provisional; Region: PRK11653
85569009343	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
85569009344	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
85569009345	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
85569009346	putative active site [active]
85569009347	metal binding site [ion binding]; metal-binding site
85569009348	zinc transporter ZupT; Provisional; Region: PRK04201
85569009349	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
85569009350	Arylsulfotransferase (ASST); Region: Arylsulfotrans; cl19972
85569009351	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
85569009352	catalytic residues [active]
85569009353	hinge region; other site
85569009354	alpha helical domain; other site
85569009355	putative disulfide oxidoreductase; Provisional; Region: PRK04307
85569009356	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
85569009357	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
85569009358	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
85569009359	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
85569009360	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
85569009361	Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_flotillin; cd03399
85569009362	core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_like; cl19107
85569009363	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
85569009364	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
85569009365	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
85569009366	putative ribose interaction site [chemical binding]; other site
85569009367	putative ADP binding site [chemical binding]; other site
85569009368	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
85569009369	active site
85569009370	nucleotide binding site [chemical binding]; other site
85569009371	HIGH motif; other site
85569009372	KMSKS motif; other site
85569009373	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
85569009374	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
85569009375	metal binding triad; other site
85569009376	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
85569009377	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
85569009378	metal binding triad; other site
85569009379	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; cl19627
85569009380	Uncharacterized conserved protein [Function unknown]; Region: COG3025
85569009381	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
85569009382	putative active site [active]
85569009383	putative metal binding residues [ion binding]; other site
85569009384	signature motif; other site
85569009385	putative triphosphate binding site [ion binding]; other site
85569009386	CHAD domain; Region: CHAD; pfam05235
85569009387	SH3 domain-containing protein; Provisional; Region: PRK10884
85569009388	Bacterial SH3 domain homologues; Region: SH3b; smart00287
85569009389	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
85569009390	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
85569009391	active site
85569009392	NTP binding site [chemical binding]; other site
85569009393	metal binding triad [ion binding]; metal-binding site
85569009394	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
85569009395	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
85569009396	Zn2+ binding site [ion binding]; other site
85569009397	Mg2+ binding site [ion binding]; other site
85569009398	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
85569009399	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
85569009400	homooctamer interface [polypeptide binding]; other site
85569009401	active site
85569009402	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
85569009403	UGMP family protein; Validated; Region: PRK09604
85569009404	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
85569009405	nucleotide binding site [chemical binding]; other site
85569009406	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
85569009407	DNA primase; Validated; Region: dnaG; PRK05667
85569009408	CHC2 zinc finger; Region: zf-CHC2; pfam01807
85569009409	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
85569009410	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
85569009411	active site
85569009412	metal binding site [ion binding]; metal-binding site
85569009413	interdomain interaction site; other site
85569009414	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
85569009415	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; smart00766
85569009416	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
85569009417	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
85569009418	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
85569009419	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
85569009420	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
85569009421	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
85569009422	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
85569009423	DNA binding residues [nucleotide binding]
85569009424	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
85569009425	active site
85569009426	SUMO-1 interface [polypeptide binding]; other site
85569009427	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
85569009428	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
85569009429	FAD binding pocket [chemical binding]; other site
85569009430	FAD binding motif [chemical binding]; other site
85569009431	phosphate binding motif [ion binding]; other site
85569009432	NAD binding pocket [chemical binding]; other site
85569009433	Predicted transcriptional regulators [Transcription]; Region: COG1695
85569009434	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
85569009435	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144
85569009436	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569009437	dimerization interface [polypeptide binding]; other site
85569009438	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cl19050
85569009439	dimer interface [polypeptide binding]; other site
85569009440	putative CheW interface [polypeptide binding]; other site
85569009441	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
85569009442	PAS fold; Region: PAS_3; pfam08447
85569009443	putative active site [active]
85569009444	heme pocket [chemical binding]; other site
85569009445	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
85569009446	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
85569009447	dimer interface [polypeptide binding]; other site
85569009448	putative CheW interface [polypeptide binding]; other site
85569009449	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
85569009450	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
85569009451	inhibitor-cofactor binding pocket; inhibition site
85569009452	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569009453	catalytic residue [active]
85569009454	mycofactocin system FadH/OYE family oxidoreductase 2; Region: mycofact_OYE_2; TIGR03997
85569009455	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
85569009456	active site
85569009457	FMN binding site [chemical binding]; other site
85569009458	2,4-decadienoyl-CoA binding site; other site
85569009459	catalytic residue [active]
85569009460	4Fe-4S cluster binding site [ion binding]; other site
85569009461	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569009462	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
85569009463	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569009464	S-adenosylmethionine binding site [chemical binding]; other site
85569009465	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
85569009466	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
85569009467	putative active site [active]
85569009468	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
85569009469	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
85569009470	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
85569009471	serine/threonine transporter SstT; Provisional; Region: PRK13628
85569009472	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
85569009473	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
85569009474	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
85569009475	Predicted membrane protein [Function unknown]; Region: COG5393
85569009476	YqjK-like protein; Region: YqjK; pfam13997
85569009477	Predicted membrane protein [Function unknown]; Region: COG2259
85569009478	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
85569009479	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
85569009480	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
85569009481	putative dimer interface [polypeptide binding]; other site
85569009482	N-terminal domain interface [polypeptide binding]; other site
85569009483	putative substrate binding pocket (H-site) [chemical binding]; other site
85569009484	Predicted membrane protein [Function unknown]; Region: COG3152
85569009485	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569009486	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
85569009487	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
85569009488	dimerization interface [polypeptide binding]; other site
85569009489	Pirin-related protein [General function prediction only]; Region: COG1741
85569009490	Pirin; Region: Pirin; pfam02678
85569009491	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
85569009492	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
85569009493	serine transporter; Region: stp; TIGR00814
85569009494	L-serine dehydratase TdcG; Provisional; Region: PRK15040
85569009495	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
85569009496	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
85569009497	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
85569009498	Pyruvate formate lyase 1; Region: PFL1; cd01678
85569009499	coenzyme A binding site [chemical binding]; other site
85569009500	active site
85569009501	catalytic residues [active]
85569009502	glycine loop; other site
85569009503	propionate/acetate kinase; Provisional; Region: PRK12379
85569009504	threonine/serine transporter TdcC; Provisional; Region: PRK13629
85569009505	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
85569009506	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
85569009507	tetramer interface [polypeptide binding]; other site
85569009508	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569009509	catalytic residue [active]
85569009510	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
85569009511	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569009512	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
85569009513	putative substrate binding pocket [chemical binding]; other site
85569009514	putative dimerization interface [polypeptide binding]; other site
85569009515	glycerate kinase I; Provisional; Region: PRK10342
85569009516	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
85569009517	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
85569009518	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833
85569009519	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
85569009520	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
85569009521	substrate binding site [chemical binding]; other site
85569009522	ATP binding site [chemical binding]; other site
85569009523	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
85569009524	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
85569009525	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
85569009526	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
85569009527	intersubunit interface [polypeptide binding]; other site
85569009528	active site
85569009529	zinc binding site [ion binding]; other site
85569009530	Na+ binding site [ion binding]; other site
85569009531	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
85569009532	putative substrate binding site [chemical binding]; other site
85569009533	putative ATP binding site [chemical binding]; other site
85569009534	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
85569009535	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
85569009536	active site
85569009537	P-loop; other site
85569009538	phosphorylation site [posttranslational modification]
85569009539	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
85569009540	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
85569009541	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
85569009542	active site
85569009543	phosphorylation site [posttranslational modification]
85569009544	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
85569009545	dimerization domain swap beta strand [polypeptide binding]; other site
85569009546	regulatory protein interface [polypeptide binding]; other site
85569009547	active site
85569009548	regulatory phosphorylation site [posttranslational modification]; other site
85569009549	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
85569009550	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
85569009551	active site
85569009552	phosphorylation site [posttranslational modification]
85569009553	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
85569009554	active site
85569009555	P-loop; other site
85569009556	phosphorylation site [posttranslational modification]
85569009557	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
85569009558	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
85569009559	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
85569009560	putative NAD(P) binding site [chemical binding]; other site
85569009561	catalytic Zn binding site [ion binding]; other site
85569009562	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
85569009563	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
85569009564	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
85569009565	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
85569009566	putative SAM binding site [chemical binding]; other site
85569009567	putative homodimer interface [polypeptide binding]; other site
85569009568	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
85569009569	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
85569009570	putative ligand binding site [chemical binding]; other site
85569009571	TIGR00252 family protein; Region: TIGR00252
85569009572	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
85569009573	dimer interface [polypeptide binding]; other site
85569009574	active site
85569009575	outer membrane lipoprotein; Provisional; Region: PRK11023
85569009576	BON domain; Region: BON; pfam04972
85569009577	BON domain; Region: BON; pfam04972
85569009578	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
85569009579	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
85569009580	NAD(P) binding site [chemical binding]; other site
85569009581	active site
85569009582	intracellular protease, PfpI family; Region: PfpI; TIGR01382
85569009583	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
85569009584	proposed catalytic triad [active]
85569009585	conserved cys residue [active]
85569009586	hypothetical protein; Provisional; Region: PRK03467
85569009587	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
85569009588	GIY-YIG motif/motif A; other site
85569009589	putative active site [active]
85569009590	putative metal binding site [ion binding]; other site
85569009591	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
85569009592	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569009593	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
85569009594	Coenzyme A binding pocket [chemical binding]; other site
85569009595	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
85569009596	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
85569009597	putative protease; Provisional; Region: PRK15447
85569009598	hypothetical protein; Provisional; Region: PRK10508
85569009599	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
85569009600	tryptophan permease; Provisional; Region: PRK10483
85569009601	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
85569009602	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
85569009603	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
85569009604	ATP binding site [chemical binding]; other site
85569009605	Mg++ binding site [ion binding]; other site
85569009606	motif III; other site
85569009607	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
85569009608	nucleotide binding region [chemical binding]; other site
85569009609	ATP-binding site [chemical binding]; other site
85569009610	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
85569009611	putative RNA binding site [nucleotide binding]; other site
85569009612	Cold shock protein DEAD box A; Region: DEADboxA; pfam12343
85569009613	lipoprotein NlpI; Provisional; Region: PRK11189
85569009614	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
85569009615	binding surface
85569009616	TPR motif; other site
85569009617	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
85569009618	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
85569009619	RNase E interface [polypeptide binding]; other site
85569009620	trimer interface [polypeptide binding]; other site
85569009621	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
85569009622	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
85569009623	RNase E interface [polypeptide binding]; other site
85569009624	trimer interface [polypeptide binding]; other site
85569009625	active site
85569009626	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
85569009627	putative nucleic acid binding region [nucleotide binding]; other site
85569009628	G-X-X-G motif; other site
85569009629	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
85569009630	RNA binding site [nucleotide binding]; other site
85569009631	domain interface; other site
85569009632	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
85569009633	16S/18S rRNA binding site [nucleotide binding]; other site
85569009634	S13e-L30e interaction site [polypeptide binding]; other site
85569009635	25S rRNA binding site [nucleotide binding]; other site
85569009636	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
85569009637	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
85569009638	RNA binding site [nucleotide binding]; other site
85569009639	active site
85569009640	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
85569009641	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
85569009642	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
85569009643	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
85569009644	translation initiation factor IF-2; Validated; Region: infB; PRK05306
85569009645	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
85569009646	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
85569009647	G1 box; other site
85569009648	putative GEF interaction site [polypeptide binding]; other site
85569009649	GTP/Mg2+ binding site [chemical binding]; other site
85569009650	Switch I region; other site
85569009651	G2 box; other site
85569009652	G3 box; other site
85569009653	Switch II region; other site
85569009654	G4 box; other site
85569009655	G5 box; other site
85569009656	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
85569009657	Translation-initiation factor 2; Region: IF-2; pfam11987
85569009658	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
85569009659	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
85569009660	NusA N-terminal domain; Region: NusA_N; pfam08529
85569009661	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
85569009662	RNA binding site [nucleotide binding]; other site
85569009663	homodimer interface [polypeptide binding]; other site
85569009664	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
85569009665	G-X-X-G motif; other site
85569009666	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
85569009667	G-X-X-G motif; other site
85569009668	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
85569009669	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
85569009670	hypothetical protein; Provisional; Region: PRK14641
85569009671	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
85569009672	putative oligomer interface [polypeptide binding]; other site
85569009673	putative RNA binding site [nucleotide binding]; other site
85569009674	argininosuccinate synthase; Validated; Region: PRK05370
85569009675	Domain of unknown function (DUF1963); Region: DUF1963; cl01600
85569009676	Preprotein translocase SecG subunit; Region: SecG; pfam03840
85569009677	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
85569009678	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
85569009679	active site
85569009680	substrate binding site [chemical binding]; other site
85569009681	metal binding site [ion binding]; metal-binding site
85569009682	Dihydropteroate synthase and related enzymes [Coenzyme metabolism]; Region: FolP; COG0294
85569009683	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
85569009684	substrate binding pocket [chemical binding]; other site
85569009685	dimer interface [polypeptide binding]; other site
85569009686	inhibitor binding site; inhibition site
85569009687	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
85569009688	FtsH Extracellular; Region: FtsH_ext; pfam06480
85569009689	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569009690	Walker A motif; other site
85569009691	ATP binding site [chemical binding]; other site
85569009692	Walker B motif; other site
85569009693	arginine finger; other site
85569009694	Peptidase family M41; Region: Peptidase_M41; pfam01434
85569009695	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569009696	S-adenosylmethionine binding site [chemical binding]; other site
85569009697	RNA-binding protein YhbY; Provisional; Region: PRK10343
85569009698	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
85569009699	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
85569009700	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
85569009701	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
85569009702	D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Cell envelope biogenesis, outer membrane]; Region: DacB; COG2027
85569009703	GTPase CgtA; Reviewed; Region: obgE; PRK12298
85569009704	GTP1/OBG; Region: GTP1_OBG; pfam01018
85569009705	Obg GTPase; Region: Obg; cd01898
85569009706	G1 box; other site
85569009707	GTP/Mg2+ binding site [chemical binding]; other site
85569009708	Switch I region; other site
85569009709	G2 box; other site
85569009710	G3 box; other site
85569009711	Switch II region; other site
85569009712	G4 box; other site
85569009713	G5 box; other site
85569009714	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
85569009715	EamA-like transporter family; Region: EamA; pfam00892
85569009716	EamA-like transporter family; Region: EamA; pfam00892
85569009717	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
85569009718	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
85569009719	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
85569009720	substrate binding pocket [chemical binding]; other site
85569009721	chain length determination region; other site
85569009722	substrate-Mg2+ binding site; other site
85569009723	catalytic residues [active]
85569009724	aspartate-rich region 1; other site
85569009725	active site lid residues [active]
85569009726	aspartate-rich region 2; other site
85569009727	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
85569009728	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Region: EPSP_synthase; pfam00275
85569009729	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
85569009730	hinge; other site
85569009731	active site
85569009732	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
85569009733	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
85569009734	anti sigma factor interaction site; other site
85569009735	regulatory phosphorylation site [posttranslational modification]; other site
85569009736	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
85569009737	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
85569009738	mce related protein; Region: MCE; pfam02470
85569009739	conserved hypothetical integral membrane protein; Region: TIGR00056
85569009740	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
85569009741	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
85569009742	Walker A/P-loop; other site
85569009743	ATP binding site [chemical binding]; other site
85569009744	Q-loop/lid; other site
85569009745	ABC transporter signature motif; other site
85569009746	Walker B; other site
85569009747	D-loop; other site
85569009748	H-loop/switch region; other site
85569009749	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
85569009750	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
85569009751	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
85569009752	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
85569009753	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
85569009754	putative active site [active]
85569009755	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
85569009756	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
85569009757	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
85569009758	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
85569009759	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
85569009760	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
85569009761	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
85569009762	Walker A/P-loop; other site
85569009763	ATP binding site [chemical binding]; other site
85569009764	Q-loop/lid; other site
85569009765	ABC transporter signature motif; other site
85569009766	Walker B; other site
85569009767	D-loop; other site
85569009768	H-loop/switch region; other site
85569009769	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
85569009770	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
85569009771	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
85569009772	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
85569009773	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
85569009774	30S subunit binding site; other site
85569009775	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
85569009776	active site
85569009777	phosphorylation site [posttranslational modification]
85569009778	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
85569009779	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
85569009780	dimerization domain swap beta strand [polypeptide binding]; other site
85569009781	regulatory protein interface [polypeptide binding]; other site
85569009782	active site
85569009783	regulatory phosphorylation site [posttranslational modification]; other site
85569009784	hypothetical protein; Provisional; Region: PRK10345
85569009785	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
85569009786	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
85569009787	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
85569009788	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
85569009789	conserved cys residue [active]
85569009790	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
85569009791	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
85569009792	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
85569009793	putative active site [active]
85569009794	heme pocket [chemical binding]; other site
85569009795	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569009796	dimer interface [polypeptide binding]; other site
85569009797	phosphorylation site [posttranslational modification]
85569009798	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569009799	ATP binding site [chemical binding]; other site
85569009800	Mg2+ binding site [ion binding]; other site
85569009801	G-X-G motif; other site
85569009802	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569009803	active site
85569009804	phosphorylation site [posttranslational modification]
85569009805	intermolecular recognition site; other site
85569009806	dimerization interface [polypeptide binding]; other site
85569009807	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
85569009808	putative binding surface; other site
85569009809	active site
85569009810	radical SAM protein, TIGR01212 family; Region: TIGR01212
85569009811	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569009812	FeS/SAM binding site; other site
85569009813	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
85569009814	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
85569009815	active site
85569009816	dimer interface [polypeptide binding]; other site
85569009817	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
85569009818	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
85569009819	active site
85569009820	FMN binding site [chemical binding]; other site
85569009821	substrate binding site [chemical binding]; other site
85569009822	3Fe-4S cluster binding site [ion binding]; other site
85569009823	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
85569009824	domain interface; other site
85569009825	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
85569009826	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster; Region: Fer4_20; pfam14691
85569009827	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569009828	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
85569009829	Protein of unknown function (DUF1016); Region: DUF1016; cl19557
85569009830	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
85569009831	Na binding site [ion binding]; other site
85569009832	putative substrate binding site [chemical binding]; other site
85569009833	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
85569009834	Cytosine deaminase and related metal-dependent hydrolases [Nucleotide transport and metabolism / General function prediction only]; Region: SsnA; COG0402
85569009835	active site
85569009836	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
85569009837	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
85569009838	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
85569009839	nucleotide binding site [chemical binding]; other site
85569009840	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
85569009841	putative active site cavity [active]
85569009842	putative sialic acid transporter; Provisional; Region: PRK03893
85569009843	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569009844	putative substrate translocation pore; other site
85569009845	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
85569009846	inhibitor site; inhibition site
85569009847	active site
85569009848	dimer interface [polypeptide binding]; other site
85569009849	catalytic residue [active]
85569009850	transcriptional regulator NanR; Provisional; Region: PRK03837
85569009851	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569009852	DNA-binding site [nucleotide binding]; DNA binding site
85569009853	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
85569009854	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
85569009855	stringent starvation protein A; Provisional; Region: sspA; PRK09481
85569009856	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
85569009857	C-terminal domain interface [polypeptide binding]; other site
85569009858	putative GSH binding site (G-site) [chemical binding]; other site
85569009859	dimer interface [polypeptide binding]; other site
85569009860	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
85569009861	dimer interface [polypeptide binding]; other site
85569009862	N-terminal domain interface [polypeptide binding]; other site
85569009863	Family of unknown function (DUF695); Region: DUF695; pfam05117
85569009864	Regulator of ribonuclease activity B; Region: RraB; pfam06877
85569009865	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
85569009866	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
85569009867	23S rRNA interface [nucleotide binding]; other site
85569009868	L3 interface [polypeptide binding]; other site
85569009869	Predicted ATPase [General function prediction only]; Region: COG1485
85569009870	hypothetical protein; Provisional; Region: PRK11677
85569009871	serine endoprotease; Provisional; Region: PRK10139
85569009872	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
85569009873	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
85569009874	protein binding site [polypeptide binding]; other site
85569009875	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
85569009876	serine endoprotease; Provisional; Region: PRK10898
85569009877	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
85569009878	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
85569009879	protein binding site [polypeptide binding]; other site
85569009880	Triphosphoribosyl-dephospho-CoA synthetase [Coenzyme metabolism]; Region: CitG; COG1767
85569009881	oxaloacetate decarboxylase subunit beta; Provisional; Region: PRK15477
85569009882	oxaloacetate decarboxylase; Provisional; Region: PRK14040
85569009883	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
85569009884	active site
85569009885	catalytic residues [active]
85569009886	metal binding site [ion binding]; metal-binding site
85569009887	homodimer binding site [polypeptide binding]; other site
85569009888	Conserved carboxylase domain; Region: PYC_OADA; pfam02436
85569009889	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
85569009890	carboxyltransferase (CT) interaction site; other site
85569009891	biotinylation site [posttranslational modification]; other site
85569009892	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
85569009893	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
85569009894	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
85569009895	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
85569009896	transmembrane helices; other site
85569009897	Transcriptional regulators [Transcription]; Region: GntR; COG1802
85569009898	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569009899	DNA-binding site [nucleotide binding]; DNA binding site
85569009900	FCD domain; Region: FCD; pfam07729
85569009901	Transcriptional regulators [Transcription]; Region: GntR; COG1802
85569009902	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
85569009903	DNA-binding site [nucleotide binding]; DNA binding site
85569009904	malate dehydrogenase; Provisional; Region: PRK05086
85569009905	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
85569009906	NAD binding site [chemical binding]; other site
85569009907	dimerization interface [polypeptide binding]; other site
85569009908	Substrate binding site [chemical binding]; other site
85569009909	arginine repressor; Provisional; Region: PRK05066
85569009910	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
85569009911	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
85569009912	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
85569009913	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
85569009914	Barstar, RNAse (barnase) inhibitor [Transcription]; Region: COG2732
85569009915	RNAase interaction site [polypeptide binding]; other site
85569009916	Predicted membrane protein [Function unknown]; Region: COG1289
85569009917	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
85569009918	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
85569009919	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
85569009920	HlyD family secretion protein; Region: HlyD_3; pfam13437
85569009921	efflux system membrane protein; Provisional; Region: PRK11594
85569009922	transcriptional regulator; Provisional; Region: PRK10632
85569009923	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569009924	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
85569009925	putative effector binding pocket; other site
85569009926	dimerization interface [polypeptide binding]; other site
85569009927	protease TldD; Provisional; Region: tldD; PRK10735
85569009928	hypothetical protein; Provisional; Region: PRK10899
85569009929	Protein of unknown function; Region: DUF3971; pfam13116
85569009930	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
85569009931	ribonuclease G; Provisional; Region: PRK11712
85569009932	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
85569009933	homodimer interface [polypeptide binding]; other site
85569009934	oligonucleotide binding site [chemical binding]; other site
85569009935	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
85569009936	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
85569009937	active site
85569009938	dimer interface [polypeptide binding]; other site
85569009939	rod shape-determining protein MreD; Provisional; Region: PRK11060
85569009940	rod shape-determining protein MreC; Region: mreC; TIGR00219
85569009941	rod shape-determining protein MreB; Provisional; Region: PRK13927
85569009942	MreB and similar proteins; Region: MreB_like; cd10225
85569009943	nucleotide binding site [chemical binding]; other site
85569009944	Mg binding site [ion binding]; other site
85569009945	putative protofilament interaction site [polypeptide binding]; other site
85569009946	RodZ interaction site [polypeptide binding]; other site
85569009947	regulatory protein CsrD; Provisional; Region: PRK11059
85569009948	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
85569009949	metal binding site [ion binding]; metal-binding site
85569009950	nucleotidyl binding site; other site
85569009951	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
85569009952	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
85569009953	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
85569009954	NADP binding site [chemical binding]; other site
85569009955	dimer interface [polypeptide binding]; other site
85569009956	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
85569009957	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
85569009958	Moco binding site; other site
85569009959	metal coordination site [ion binding]; other site
85569009960	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
85569009961	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
85569009962	carboxyltransferase (CT) interaction site; other site
85569009963	biotinylation site [posttranslational modification]; other site
85569009964	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
85569009965	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
85569009966	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
85569009967	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
85569009968	hypothetical protein; Provisional; Region: PRK10633
85569009969	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
85569009970	Na binding site [ion binding]; other site
85569009971	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
85569009972	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569009973	S-adenosylmethionine binding site [chemical binding]; other site
85569009974	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
85569009975	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
85569009976	FMN binding site [chemical binding]; other site
85569009977	active site
85569009978	catalytic residues [active]
85569009979	substrate binding site [chemical binding]; other site
85569009980	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
85569009981	putative methyltransferase; Provisional; Region: PRK11524
85569009982	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569009983	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
85569009984	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
85569009985	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
85569009986	Cytochrome oxidase subunit II; Region: Cyto_ox_2; cl12219
85569009987	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
85569009988	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
85569009989	metal binding site [ion binding]; metal-binding site
85569009990	active site
85569009991	I-site; other site
85569009992	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
85569009993	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
85569009994	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
85569009995	HlyD family secretion protein; Region: HlyD_3; pfam13437
85569009996	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
85569009997	MMPL family; Region: MMPL; cl14618
85569009998	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
85569009999	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
85569010000	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
85569010001	trimer interface [polypeptide binding]; other site
85569010002	putative metal binding site [ion binding]; other site
85569010003	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
85569010004	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
85569010005	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
85569010006	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
85569010007	shikimate binding site; other site
85569010008	NAD(P) binding site [chemical binding]; other site
85569010009	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
85569010010	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
85569010011	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
85569010012	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
85569010013	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
85569010014	hypothetical protein; Validated; Region: PRK03430
85569010015	hypothetical protein; Provisional; Region: PRK10736
85569010016	DNA protecting protein DprA; Region: dprA; TIGR00732
85569010017	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
85569010018	active site
85569010019	catalytic residues [active]
85569010020	metal binding site [ion binding]; metal-binding site
85569010021	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
85569010022	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
85569010023	putative active site [active]
85569010024	substrate binding site [chemical binding]; other site
85569010025	putative cosubstrate binding site; other site
85569010026	catalytic site [active]
85569010027	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
85569010028	substrate binding site [chemical binding]; other site
85569010029	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
85569010030	putative RNA binding site [nucleotide binding]; other site
85569010031	16S rRNA methyltransferase B; Provisional; Region: PRK10901
85569010032	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569010033	S-adenosylmethionine binding site [chemical binding]; other site
85569010034	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
85569010035	TrkA-N domain; Region: TrkA_N; pfam02254
85569010036	TrkA-C domain; Region: TrkA_C; pfam02080
85569010037	TrkA-N domain; Region: TrkA_N; pfam02254
85569010038	TrkA-C domain; Region: TrkA_C; pfam02080
85569010039	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
85569010040	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
85569010041	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
85569010042	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
85569010043	DNA binding residues [nucleotide binding]
85569010044	dimer interface [polypeptide binding]; other site
85569010045	metal binding site [ion binding]; metal-binding site
85569010046	hypothetical protein; Provisional; Region: PRK10203
85569010047	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
85569010048	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
85569010049	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
85569010050	alphaNTD homodimer interface [polypeptide binding]; other site
85569010051	alphaNTD - beta interaction site [polypeptide binding]; other site
85569010052	alphaNTD - beta' interaction site [polypeptide binding]; other site
85569010053	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
85569010054	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
85569010055	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
85569010056	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
85569010057	RNA binding surface [nucleotide binding]; other site
85569010058	30S ribosomal protein S11; Validated; Region: PRK05309
85569010059	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
85569010060	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
85569010061	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
85569010062	SecY translocase; Region: SecY; pfam00344
85569010063	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
85569010064	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
85569010065	23S rRNA binding site [nucleotide binding]; other site
85569010066	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
85569010067	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
85569010068	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
85569010069	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
85569010070	23S rRNA interface [nucleotide binding]; other site
85569010071	5S rRNA interface [nucleotide binding]; other site
85569010072	L27 interface [polypeptide binding]; other site
85569010073	L5 interface [polypeptide binding]; other site
85569010074	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
85569010075	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
85569010076	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
85569010077	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
85569010078	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
85569010079	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
85569010080	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
85569010081	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
85569010082	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
85569010083	RNA binding site [nucleotide binding]; other site
85569010084	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
85569010085	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
85569010086	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
85569010087	23S rRNA interface [nucleotide binding]; other site
85569010088	5S rRNA interface [nucleotide binding]; other site
85569010089	putative antibiotic binding site [chemical binding]; other site
85569010090	L25 interface [polypeptide binding]; other site
85569010091	L27 interface [polypeptide binding]; other site
85569010092	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
85569010093	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
85569010094	G-X-X-G motif; other site
85569010095	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
85569010096	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
85569010097	putative translocon binding site; other site
85569010098	protein-rRNA interface [nucleotide binding]; other site
85569010099	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
85569010100	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
85569010101	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
85569010102	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
85569010103	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
85569010104	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
85569010105	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
85569010106	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
85569010107	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
85569010108	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
85569010109	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
85569010110	Ferritin-like domain; Region: Ferritin; pfam00210
85569010111	heme binding site [chemical binding]; other site
85569010112	ferroxidase pore; other site
85569010113	ferroxidase diiron center [ion binding]; other site
85569010114	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
85569010115	elongation factor Tu; Reviewed; Region: PRK00049
85569010116	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
85569010117	G1 box; other site
85569010118	GEF interaction site [polypeptide binding]; other site
85569010119	GTP/Mg2+ binding site [chemical binding]; other site
85569010120	Switch I region; other site
85569010121	G2 box; other site
85569010122	G3 box; other site
85569010123	Switch II region; other site
85569010124	G4 box; other site
85569010125	G5 box; other site
85569010126	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
85569010127	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
85569010128	Antibiotic Binding Site [chemical binding]; other site
85569010129	elongation factor G; Reviewed; Region: PRK00007
85569010130	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
85569010131	G1 box; other site
85569010132	putative GEF interaction site [polypeptide binding]; other site
85569010133	GTP/Mg2+ binding site [chemical binding]; other site
85569010134	Switch I region; other site
85569010135	G2 box; other site
85569010136	G3 box; other site
85569010137	Switch II region; other site
85569010138	G4 box; other site
85569010139	G5 box; other site
85569010140	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
85569010141	Elongation Factor G, domain II; Region: EFG_II; pfam14492
85569010142	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
85569010143	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
85569010144	30S ribosomal protein S7; Validated; Region: PRK05302
85569010145	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
85569010146	S17 interaction site [polypeptide binding]; other site
85569010147	S8 interaction site; other site
85569010148	16S rRNA interaction site [nucleotide binding]; other site
85569010149	streptomycin interaction site [chemical binding]; other site
85569010150	23S rRNA interaction site [nucleotide binding]; other site
85569010151	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
85569010152	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
85569010153	sulfur relay protein TusC; Validated; Region: PRK00211
85569010154	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
85569010155	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
85569010156	YheO-like PAS domain; Region: PAS_6; pfam08348
85569010157	HTH domain; Region: HTH_22; pfam13309
85569010158	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
85569010159	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
85569010160	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
85569010161	phi X174 lysis protein; Provisional; Region: PRK02793
85569010162	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10737
85569010163	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
85569010164	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
85569010165	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
85569010166	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
85569010167	TrkA-N domain; Region: TrkA_N; pfam02254
85569010168	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
85569010169	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
85569010170	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
85569010171	ABC transporter; Region: ABC_tran_2; pfam12848
85569010172	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
85569010173	putative monooxygenase; Provisional; Region: PRK11118
85569010174	Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]; Region: COG0429
85569010175	putative hydrolase; Provisional; Region: PRK10985
85569010176	Uncharacterized protein family (UPF0270); Region: UPF0270; cl01180
85569010177	phosphoribulokinase; Provisional; Region: PRK15453
85569010178	active site
85569010179	hypothetical protein; Provisional; Region: PRK10738
85569010180	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
85569010181	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
85569010182	ligand binding site [chemical binding]; other site
85569010183	flexible hinge region; other site
85569010184	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
85569010185	putative switch regulator; other site
85569010186	non-specific DNA interactions [nucleotide binding]; other site
85569010187	DNA binding site [nucleotide binding]
85569010188	sequence specific DNA binding site [nucleotide binding]; other site
85569010189	putative cAMP binding site [chemical binding]; other site
85569010190	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
85569010191	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
85569010192	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
85569010193	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
85569010194	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
85569010195	inhibitor-cofactor binding pocket; inhibition site
85569010196	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569010197	catalytic residue [active]
85569010198	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
85569010199	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
85569010200	glutamine binding [chemical binding]; other site
85569010201	catalytic triad [active]
85569010202	cell filamentation protein Fic; Provisional; Region: PRK10347
85569010203	hypothetical protein; Provisional; Region: PRK10204
85569010204	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
85569010205	substrate binding site [chemical binding]; other site
85569010206	putative transporter; Provisional; Region: PRK03699
85569010207	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569010208	putative substrate translocation pore; other site
85569010209	nitrite reductase subunit NirD; Provisional; Region: PRK14989
85569010210	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
85569010211	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
85569010212	Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077
85569010213	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
85569010214	nitrite transporter NirC; Provisional; Region: PRK11562
85569010215	siroheme synthase; Provisional; Region: cysG; PRK10637
85569010216	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
85569010217	Sirohaem biosynthesis protein central; Region: Sirohm_synth_M; pfam14824
85569010218	Sirohaem synthase dimerization region; Region: CysG_dimeriser; pfam10414
85569010219	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
85569010220	active site
85569010221	SAM binding site [chemical binding]; other site
85569010222	homodimer interface [polypeptide binding]; other site
85569010223	Autotransporter beta-domain; Region: Autotransporter; pfam03797
85569010224	Transposase IS200 like; Region: Y1_Tnp; pfam01797
85569010225	tryptophanyl-tRNA synthetase; Reviewed; Region: PRK00927
85569010226	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
85569010227	active site
85569010228	HIGH motif; other site
85569010229	dimer interface [polypeptide binding]; other site
85569010230	KMSKS motif; other site
85569010231	phosphoglycolate phosphatase; Provisional; Region: PRK13222
85569010232	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
85569010233	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569010234	motif II; other site
85569010235	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
85569010236	substrate binding site [chemical binding]; other site
85569010237	hexamer interface [polypeptide binding]; other site
85569010238	metal binding site [ion binding]; metal-binding site
85569010239	DNA adenine methylase; Provisional; Region: PRK10904
85569010240	cell division protein DamX; Validated; Region: PRK10905
85569010241	Sporulation related domain; Region: SPOR; pfam05036
85569010242	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
85569010243	active site
85569010244	dimer interface [polypeptide binding]; other site
85569010245	metal binding site [ion binding]; metal-binding site
85569010246	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
85569010247	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
85569010248	ADP binding site [chemical binding]; other site
85569010249	magnesium binding site [ion binding]; other site
85569010250	putative shikimate binding site; other site
85569010251	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
85569010252	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
85569010253	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
85569010254	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
85569010255	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
85569010256	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
85569010257	Transglycosylase; Region: Transgly; pfam00912
85569010258	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
85569010259	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
85569010260	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
85569010261	ADP-ribose binding site [chemical binding]; other site
85569010262	dimer interface [polypeptide binding]; other site
85569010263	active site
85569010264	nudix motif; other site
85569010265	metal binding site [ion binding]; metal-binding site
85569010266	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
85569010267	GMP/IMP nucleotidase; Provisional; Region: PRK14988
85569010268	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
85569010269	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569010270	motif II; other site
85569010271	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
85569010272	RNA binding surface [nucleotide binding]; other site
85569010273	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
85569010274	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
85569010275	dimerization interface [polypeptide binding]; other site
85569010276	domain crossover interface; other site
85569010277	redox-dependent activation switch; other site
85569010278	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
85569010279	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
85569010280	active site
85569010281	substrate-binding site [chemical binding]; other site
85569010282	metal-binding site [ion binding]
85569010283	ATP binding site [chemical binding]; other site
85569010284	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
85569010285	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569010286	dimerization interface [polypeptide binding]; other site
85569010287	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569010288	dimer interface [polypeptide binding]; other site
85569010289	phosphorylation site [posttranslational modification]
85569010290	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569010291	ATP binding site [chemical binding]; other site
85569010292	Mg2+ binding site [ion binding]; other site
85569010293	G-X-G motif; other site
85569010294	osmolarity response regulator; Provisional; Region: ompR; PRK09468
85569010295	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569010296	active site
85569010297	phosphorylation site [posttranslational modification]
85569010298	intermolecular recognition site; other site
85569010299	dimerization interface [polypeptide binding]; other site
85569010300	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
85569010301	DNA binding site [nucleotide binding]
85569010302	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
85569010303	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
85569010304	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
85569010305	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
85569010306	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
85569010307	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
85569010308	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
85569010309	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
85569010310	RNA binding site [nucleotide binding]; other site
85569010311	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
85569010312	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
85569010313	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
85569010314	G1 box; other site
85569010315	GTP/Mg2+ binding site [chemical binding]; other site
85569010316	Switch I region; other site
85569010317	G2 box; other site
85569010318	G3 box; other site
85569010319	Switch II region; other site
85569010320	G4 box; other site
85569010321	G5 box; other site
85569010322	Nucleoside recognition; Region: Gate; pfam07670
85569010323	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
85569010324	Nucleoside recognition; Region: Gate; pfam07670
85569010325	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
85569010326	hypothetical protein; Provisional; Region: PRK09956
85569010327	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
85569010328	carboxylesterase BioH; Provisional; Region: PRK10349
85569010329	Putative lysophospholipase; Region: Hydrolase_4; cl19140
85569010330	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
85569010331	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
85569010332	active site
85569010333	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
85569010334	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
85569010335	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
85569010336	high-affinity gluconate transporter; Provisional; Region: PRK14984
85569010337	GntP family permease; Region: GntP_permease; pfam02447
85569010338	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
85569010339	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
85569010340	maltodextrin phosphorylase; Provisional; Region: PRK14985
85569010341	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
85569010342	homodimer interface [polypeptide binding]; other site
85569010343	active site pocket [active]
85569010344	transcriptional regulator MalT; Provisional; Region: PRK04841
85569010345	AAA ATPase domain; Region: AAA_16; pfam13191
85569010346	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569010347	DNA binding residues [nucleotide binding]
85569010348	dimerization interface [polypeptide binding]; other site
85569010349	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
85569010350	DNA-damage-inducible protein J [DNA replication, recombination, and repair]; Region: RelB; COG3077
85569010351	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
85569010352	RNA 3' phosphate cyclase domain (class II). These proteins function as RNA cyclase to catalyze the ATP-dependent conversion of 3'-phosphate to a 2'.3'-cyclic phosphodiester at the end of RNA molecule. A conserved catalytic histidine...; Region: RNA_Cyclase_Class_II; cd00874
85569010353	putative active site [active]
85569010354	adenylation catalytic residue [active]
85569010355	Uncharacterized conserved protein [Function unknown]; Region: RtcB; COG1690
85569010356	tRNA-splicing ligase RtcB; Region: RtcB; pfam01139
85569010357	TROVE domain; Region: TROVE; pfam05731
85569010358	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
85569010359	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
85569010360	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569010361	Walker A motif; other site
85569010362	ATP binding site [chemical binding]; other site
85569010363	Walker B motif; other site
85569010364	arginine finger; other site
85569010365	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
85569010366	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
85569010367	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
85569010368	intramembrane serine protease GlpG; Provisional; Region: PRK10907
85569010369	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
85569010370	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
85569010371	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
85569010372	active site residue [active]
85569010373	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
85569010374	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
85569010375	hypothetical protein; Provisional; Region: PRK09781
85569010376	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
85569010377	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
85569010378	dimer interface [polypeptide binding]; other site
85569010379	active site
85569010380	metal binding site [ion binding]; metal-binding site
85569010381	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569010382	D-galactonate transporter; Region: 2A0114; TIGR00893
85569010383	putative substrate translocation pore; other site
85569010384	Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism / Carbohydrate transport and metabolism]; Region: IlvD; COG0129
85569010385	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
85569010386	inhibitor site; inhibition site
85569010387	active site
85569010388	dimer interface [polypeptide binding]; other site
85569010389	catalytic residue [active]
85569010390	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
85569010391	Transcriptional regulator [Transcription]; Region: IclR; COG1414
85569010392	Bacterial transcriptional regulator; Region: IclR; pfam01614
85569010393	glycogen phosphorylase; Provisional; Region: PRK14986
85569010394	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
85569010395	homodimer interface [polypeptide binding]; other site
85569010396	active site pocket [active]
85569010397	glycogen synthase; Provisional; Region: glgA; PRK00654
85569010398	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
85569010399	ADP-binding pocket [chemical binding]; other site
85569010400	homodimer interface [polypeptide binding]; other site
85569010401	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
85569010402	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
85569010403	ligand binding site; other site
85569010404	oligomer interface; other site
85569010405	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
85569010406	dimer interface [polypeptide binding]; other site
85569010407	N-terminal domain interface [polypeptide binding]; other site
85569010408	sulfate 1 binding site; other site
85569010409	glycogen debranching enzyme; Provisional; Region: PRK03705
85569010410	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
85569010411	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
85569010412	active site
85569010413	catalytic site [active]
85569010414	glycogen branching enzyme; Provisional; Region: PRK05402
85569010415	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
85569010416	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
85569010417	active site
85569010418	catalytic site [active]
85569010419	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
85569010420	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
85569010421	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118
85569010422	Semialdehyde dehydrogenase, dimerization domain; Region: Semialdhyde_dhC; pfam02774
85569010423	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
85569010424	low affinity gluconate transporter; Provisional; Region: PRK10472
85569010425	GntP family permease; Region: GntP_permease; pfam02447
85569010426	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
85569010427	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
85569010428	ATP-binding site [chemical binding]; other site
85569010429	Gluconate-6-phosphate binding site [chemical binding]; other site
85569010430	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
85569010431	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
85569010432	DNA binding site [nucleotide binding]
85569010433	domain linker motif; other site
85569010434	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
85569010435	putative ligand binding site [chemical binding]; other site
85569010436	putative dimerization interface [polypeptide binding]; other site
85569010437	Pirin-related protein [General function prediction only]; Region: COG1741
85569010438	Pirin; Region: Pirin; pfam02678
85569010439	putative oxidoreductase; Provisional; Region: PRK10206
85569010440	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
85569010441	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
85569010442	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
85569010443	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569010444	Coenzyme A binding pocket [chemical binding]; other site
85569010445	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
85569010446	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
85569010447	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
85569010448	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
85569010449	substrate binding site [chemical binding]; other site
85569010450	dimer interface [polypeptide binding]; other site
85569010451	ATP binding site [chemical binding]; other site
85569010452	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
85569010453	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
85569010454	Protein of unknown function, DUF606; Region: DUF606; pfam04657
85569010455	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
85569010456	active site
85569010457	substrate binding pocket [chemical binding]; other site
85569010458	homodimer interaction site [polypeptide binding]; other site
85569010459	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
85569010460	hypothetical protein; Provisional; Region: PRK10350
85569010461	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
85569010462	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
85569010463	putative active site [active]
85569010464	catalytic site [active]
85569010465	putative metal binding site [ion binding]; other site
85569010466	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
85569010467	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
85569010468	Walker A/P-loop; other site
85569010469	ATP binding site [chemical binding]; other site
85569010470	Q-loop/lid; other site
85569010471	ABC transporter signature motif; other site
85569010472	Walker B; other site
85569010473	D-loop; other site
85569010474	H-loop/switch region; other site
85569010475	TOBE domain; Region: TOBE_2; pfam08402
85569010476	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
85569010477	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569010478	dimer interface [polypeptide binding]; other site
85569010479	conserved gate region; other site
85569010480	ABC-ATPase subunit interface; other site
85569010481	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
85569010482	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569010483	dimer interface [polypeptide binding]; other site
85569010484	conserved gate region; other site
85569010485	putative PBP binding loops; other site
85569010486	ABC-ATPase subunit interface; other site
85569010487	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
85569010488	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
85569010489	Prophage maintenance system killer protein [General function prediction only]; Region: Doc; COG3654
85569010490	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
85569010491	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
85569010492	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
85569010493	Walker A/P-loop; other site
85569010494	ATP binding site [chemical binding]; other site
85569010495	Q-loop/lid; other site
85569010496	ABC transporter signature motif; other site
85569010497	Walker B; other site
85569010498	D-loop; other site
85569010499	H-loop/switch region; other site
85569010500	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
85569010501	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
85569010502	Walker A/P-loop; other site
85569010503	ATP binding site [chemical binding]; other site
85569010504	Q-loop/lid; other site
85569010505	ABC transporter signature motif; other site
85569010506	Walker B; other site
85569010507	D-loop; other site
85569010508	H-loop/switch region; other site
85569010509	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
85569010510	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
85569010511	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
85569010512	TM-ABC transporter signature motif; other site
85569010513	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
85569010514	TM-ABC transporter signature motif; other site
85569010515	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
85569010516	dimerization interface [polypeptide binding]; other site
85569010517	Receptor family ligand binding region; Region: ANF_receptor; pfam01094
85569010518	ligand binding site [chemical binding]; other site
85569010519	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
85569010520	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
85569010521	dimerization interface [polypeptide binding]; other site
85569010522	Receptor family ligand binding region; Region: ANF_receptor; pfam01094
85569010523	ligand binding site [chemical binding]; other site
85569010524	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
85569010525	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
85569010526	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
85569010527	DNA binding residues [nucleotide binding]
85569010528	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
85569010529	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
85569010530	cell division protein FtsE; Provisional; Region: PRK10908
85569010531	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569010532	Walker A/P-loop; other site
85569010533	ATP binding site [chemical binding]; other site
85569010534	Q-loop/lid; other site
85569010535	ABC transporter signature motif; other site
85569010536	Walker B; other site
85569010537	D-loop; other site
85569010538	H-loop/switch region; other site
85569010539	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
85569010540	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
85569010541	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
85569010542	P loop; other site
85569010543	GTP binding site [chemical binding]; other site
85569010544	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569010545	S-adenosylmethionine binding site [chemical binding]; other site
85569010546	hypothetical protein; Provisional; Region: PRK10910
85569010547	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
85569010548	Predicted membrane protein [Function unknown]; Region: COG3714
85569010549	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
85569010550	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
85569010551	metal-binding site [ion binding]
85569010552	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
85569010553	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
85569010554	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
85569010555	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
85569010556	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
85569010557	dimer interface [polypeptide binding]; other site
85569010558	ligand binding site [chemical binding]; other site
85569010559	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569010560	dimerization interface [polypeptide binding]; other site
85569010561	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
85569010562	dimer interface [polypeptide binding]; other site
85569010563	putative CheW interface [polypeptide binding]; other site
85569010564	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
85569010565	CPxP  motif; other site
85569010566	hypothetical protein; Provisional; Region: PRK11212
85569010567	hypothetical protein; Provisional; Region: PRK11615
85569010568	major facilitator superfamily transporter; Provisional; Region: PRK05122
85569010569	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569010570	putative substrate translocation pore; other site
85569010571	Domain of unknown function DUF20; Region: UPF0118; cl00465
85569010572	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
85569010573	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
85569010574	nickel responsive regulator; Provisional; Region: PRK02967
85569010575	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
85569010576	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
85569010577	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
85569010578	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
85569010579	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
85569010580	Walker A/P-loop; other site
85569010581	ATP binding site [chemical binding]; other site
85569010582	Q-loop/lid; other site
85569010583	ABC transporter signature motif; other site
85569010584	Walker B; other site
85569010585	D-loop; other site
85569010586	H-loop/switch region; other site
85569010587	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569010588	Walker A/P-loop; other site
85569010589	ATP binding site [chemical binding]; other site
85569010590	Q-loop/lid; other site
85569010591	ABC transporter signature motif; other site
85569010592	Walker B; other site
85569010593	D-loop; other site
85569010594	H-loop/switch region; other site
85569010595	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
85569010596	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
85569010597	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
85569010598	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
85569010599	HlyD family secretion protein; Region: HlyD_3; pfam13437
85569010600	Predicted flavoproteins [General function prediction only]; Region: COG2081
85569010601	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569010602	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
85569010603	universal stress protein UspB; Provisional; Region: PRK04960
85569010604	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
85569010605	Ligand Binding Site [chemical binding]; other site
85569010606	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
85569010607	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569010608	putative substrate translocation pore; other site
85569010609	putative methyltransferase; Provisional; Region: PRK10742
85569010610	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569010611	S-adenosylmethionine binding site [chemical binding]; other site
85569010612	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
85569010613	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
85569010614	active site
85569010615	Zn binding site [ion binding]; other site
85569010616	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
85569010617	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
85569010618	active site
85569010619	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
85569010620	glutathione reductase; Validated; Region: PRK06116
85569010621	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569010622	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
85569010623	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
85569010624	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
85569010625	active site
85569010626	homotetramer interface [polypeptide binding]; other site
85569010627	homodimer interface [polypeptide binding]; other site
85569010628	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
85569010629	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
85569010630	substrate binding site [chemical binding]; other site
85569010631	ATP binding site [chemical binding]; other site
85569010632	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
85569010633	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
85569010634	putative active site [active]
85569010635	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
85569010636	dimer interface [polypeptide binding]; other site
85569010637	active site
85569010638	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
85569010639	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569010640	DNA-binding site [nucleotide binding]; DNA binding site
85569010641	UTRA domain; Region: UTRA; pfam07702
85569010642	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
85569010643	trehalase; Provisional; Region: treF; PRK13270
85569010644	Phage-related lysozyme (muraminidase) [General function prediction only]; Region: COG3772
85569010645	catalytic residue [active]
85569010646	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
85569010647	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl19078
85569010648	active site
85569010649	phosphorylation site [posttranslational modification]
85569010650	dimerization interface [polypeptide binding]; other site
85569010651	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569010652	DNA binding residues [nucleotide binding]
85569010653	dimerization interface [polypeptide binding]; other site
85569010654	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569010655	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569010656	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
85569010657	putative effector binding pocket; other site
85569010658	putative dimerization interface [polypeptide binding]; other site
85569010659	inner membrane protein YhjD; Region: TIGR00766
85569010660	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569010661	metabolite-proton symporter; Region: 2A0106; TIGR00883
85569010662	putative substrate translocation pore; other site
85569010663	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
85569010664	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
85569010665	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
85569010666	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
85569010667	substrate binding site [chemical binding]; other site
85569010668	ATP binding site [chemical binding]; other site
85569010669	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
85569010670	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
85569010671	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
85569010672	putative diguanylate cyclase; Provisional; Region: PRK13561
85569010673	HAMP domain; Region: HAMP; pfam00672
85569010674	diguanylate cyclase; Region: GGDEF; smart00267
85569010675	metal binding site [ion binding]; metal-binding site
85569010676	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
85569010677	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
85569010678	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
85569010679	TPR motif; other site
85569010680	binding surface
85569010681	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
85569010682	TPR motif; other site
85569010683	binding surface
85569010684	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
85569010685	binding surface
85569010686	TPR motif; other site
85569010687	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
85569010688	endo-1,4-D-glucanase; Provisional; Region: PRK11097
85569010689	cellulose synthase regulator protein; Provisional; Region: PRK11114
85569010690	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
85569010691	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
85569010692	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
85569010693	DXD motif; other site
85569010694	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
85569010695	PilZ domain; Region: PilZ; pfam07238
85569010696	cell division protein; Provisional; Region: PRK10037
85569010697	YhjQ protein; Region: YhjQ; pfam06564
85569010698	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
85569010699	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
85569010700	Protein of unknown function (DUF2636); Region: DUF2636; pfam11120
85569010701	cellulose synthase operon protein YhjU; Region: cellulose_yhjU; TIGR03368
85569010702	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
85569010703	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
85569010704	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
85569010705	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
85569010706	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
85569010707	Walker A/P-loop; other site
85569010708	ATP binding site [chemical binding]; other site
85569010709	Q-loop/lid; other site
85569010710	ABC transporter signature motif; other site
85569010711	Walker B; other site
85569010712	D-loop; other site
85569010713	H-loop/switch region; other site
85569010714	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
85569010715	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
85569010716	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
85569010717	Walker A/P-loop; other site
85569010718	ATP binding site [chemical binding]; other site
85569010719	Q-loop/lid; other site
85569010720	ABC transporter signature motif; other site
85569010721	Walker B; other site
85569010722	D-loop; other site
85569010723	H-loop/switch region; other site
85569010724	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
85569010725	dipeptide transporter; Provisional; Region: PRK10913
85569010726	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
85569010727	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569010728	dimer interface [polypeptide binding]; other site
85569010729	conserved gate region; other site
85569010730	putative PBP binding loops; other site
85569010731	ABC-ATPase subunit interface; other site
85569010732	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
85569010733	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569010734	dimer interface [polypeptide binding]; other site
85569010735	conserved gate region; other site
85569010736	putative PBP binding loops; other site
85569010737	ABC-ATPase subunit interface; other site
85569010738	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
85569010739	antimicrobial peptide ABC transporter periplasmic binding protein SapA; Provisional; Region: PRK15109
85569010740	peptide binding site [polypeptide binding]; other site
85569010741	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
85569010742	Sulfate transporter family; Region: Sulfate_transp; cl19250
85569010743	Arylsulfotransferase (ASST); Region: Arylsulfotrans; cl19972
85569010744	Transcriptional regulators [Transcription]; Region: PurR; COG1609
85569010745	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
85569010746	DNA binding site [nucleotide binding]
85569010747	domain linker motif; other site
85569010748	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_8; cd06287
85569010749	putative dimerization interface [polypeptide binding]; other site
85569010750	putative ligand binding site [chemical binding]; other site
85569010751	phosphoethanolamine transferase; Provisional; Region: PRK11560
85569010752	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
85569010753	Sulfatase; Region: Sulfatase; pfam00884
85569010754	long polar fimbrial protein LpfE; Provisional; Region: PRK15205
85569010755	long polar fimbrial protein LpfD; Provisional; Region: PRK15206
85569010756	long polar fimbrial outer membrane usher protein LpfC; Provisional; Region: PRK15207
85569010757	PapC N-terminal domain; Region: PapC_N; pfam13954
85569010758	Outer membrane usher protein; Region: Usher; pfam00577
85569010759	PapC C-terminal domain; Region: PapC_C; pfam13953
85569010760	long polar fimbrial chaperone LpfB; Provisional; Region: PRK15208
85569010761	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
85569010762	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
85569010763	long polar fimbrial protein LpfA; Provisional; Region: PRK15209
85569010764	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
85569010765	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
85569010766	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
85569010767	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569010768	Coenzyme A binding pocket [chemical binding]; other site
85569010769	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
85569010770	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
85569010771	molybdopterin cofactor binding site [chemical binding]; other site
85569010772	substrate binding site [chemical binding]; other site
85569010773	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
85569010774	molybdopterin cofactor binding site; other site
85569010775	putative outer membrane lipoprotein; Provisional; Region: PRK10510
85569010776	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
85569010777	ligand binding site [chemical binding]; other site
85569010778	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
85569010779	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
85569010780	dimerization interface [polypeptide binding]; other site
85569010781	ligand binding site [chemical binding]; other site
85569010782	NADP binding site [chemical binding]; other site
85569010783	catalytic site [active]
85569010784	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
85569010785	Predicted transcriptional regulator [Transcription]; Region: COG2944
85569010786	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569010787	salt bridge; other site
85569010788	non-specific DNA binding site [nucleotide binding]; other site
85569010789	sequence-specific DNA binding site [nucleotide binding]; other site
85569010790	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
85569010791	DNA-binding site [nucleotide binding]; DNA binding site
85569010792	RNA-binding motif; other site
85569010793	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
85569010794	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
85569010795	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
85569010796	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569010797	Coenzyme A binding pocket [chemical binding]; other site
85569010798	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
85569010799	Glycyl-tRNA synthetase beta subunit; Region: tRNA_synt_2f; pfam02092
85569010800	DALR anticodon binding domain; Region: DALR_1; pfam05746
85569010801	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
85569010802	dimer interface [polypeptide binding]; other site
85569010803	motif 1; other site
85569010804	active site
85569010805	motif 2; other site
85569010806	motif 3; other site
85569010807	YsaB-like lipoprotein; Region: YsaB; pfam13983
85569010808	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
85569010809	xylulokinase; Provisional; Region: PRK15027
85569010810	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
85569010811	N- and C-terminal domain interface [polypeptide binding]; other site
85569010812	active site
85569010813	MgATP binding site [chemical binding]; other site
85569010814	catalytic site [active]
85569010815	metal binding site [ion binding]; metal-binding site
85569010816	xylulose binding site [chemical binding]; other site
85569010817	homodimer interface [polypeptide binding]; other site
85569010818	xylose isomerase; Provisional; Region: PRK05474
85569010819	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
85569010820	putative dimerization interface [polypeptide binding]; other site
85569010821	Transcriptional regulators [Transcription]; Region: PurR; COG1609
85569010822	putative ligand binding site [chemical binding]; other site
85569010823	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569010824	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
85569010825	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569010826	hypothetical protein; Provisional; Region: PRK10356
85569010827	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
85569010828	alpha-amylase; Reviewed; Region: malS; PRK09505
85569010829	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
85569010830	active site
85569010831	catalytic site [active]
85569010832	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
85569010833	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
85569010834	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569010835	homodimer interface [polypeptide binding]; other site
85569010836	catalytic residue [active]
85569010837	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
85569010838	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
85569010839	Transcriptional regulator [Transcription]; Region: IclR; COG1414
85569010840	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
85569010841	Bacterial transcriptional regulator; Region: IclR; pfam01614
85569010842	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
85569010843	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
85569010844	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
85569010845	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
85569010846	DctM-like transporters; Region: DctM; pfam06808
85569010847	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
85569010848	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
85569010849	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
85569010850	putative N- and C-terminal domain interface [polypeptide binding]; other site
85569010851	putative active site [active]
85569010852	MgATP binding site [chemical binding]; other site
85569010853	catalytic site [active]
85569010854	metal binding site [ion binding]; metal-binding site
85569010855	putative xylulose binding site [chemical binding]; other site
85569010856	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
85569010857	active site
85569010858	dimer interface [polypeptide binding]; other site
85569010859	magnesium binding site [ion binding]; other site
85569010860	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
85569010861	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
85569010862	AP (apurinic/apyrimidinic) site pocket; other site
85569010863	DNA interaction; other site
85569010864	Metal-binding active site; metal-binding site
85569010865	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
85569010866	intersubunit interface [polypeptide binding]; other site
85569010867	active site
85569010868	Zn2+ binding site [ion binding]; other site
85569010869	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
85569010870	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
85569010871	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569010872	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
85569010873	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II and Staphylococcus aureus AldA1 (SACOL0154)-like; Region: ALDH_ACDHII_AcoD-like; cd07559
85569010874	NAD(P) binding site [chemical binding]; other site
85569010875	catalytic residues [active]
85569010876	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
85569010877	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
85569010878	nucleotide binding site [chemical binding]; other site
85569010879	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
85569010880	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
85569010881	G1 box; other site
85569010882	putative GEF interaction site [polypeptide binding]; other site
85569010883	GTP/Mg2+ binding site [chemical binding]; other site
85569010884	Switch I region; other site
85569010885	G2 box; other site
85569010886	G3 box; other site
85569010887	Switch II region; other site
85569010888	G4 box; other site
85569010889	G5 box; other site
85569010890	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
85569010891	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
85569010892	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
85569010893	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
85569010894	selenocysteine synthase; Provisional; Region: PRK04311
85569010895	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
85569010896	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
85569010897	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
85569010898	catalytic residue [active]
85569010899	putative glutathione S-transferase; Provisional; Region: PRK10357
85569010900	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
85569010901	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
85569010902	dimer interface [polypeptide binding]; other site
85569010903	N-terminal domain interface [polypeptide binding]; other site
85569010904	putative substrate binding pocket (H-site) [chemical binding]; other site
85569010905	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
85569010906	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
85569010907	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
85569010908	active site
85569010909	P-loop; other site
85569010910	phosphorylation site [posttranslational modification]
85569010911	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
85569010912	active site
85569010913	phosphorylation site [posttranslational modification]
85569010914	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
85569010915	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
85569010916	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
85569010917	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
85569010918	hypothetical protein; Provisional; Region: PRK11020
85569010919	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
85569010920	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
85569010921	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
85569010922	trimer interface [polypeptide binding]; other site
85569010923	Predicted membrane protein [Function unknown]; Region: COG1511
85569010924	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
85569010925	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
85569010926	Coiled stalk of trimeric autotransporter adhesin; Region: YadA_stalk; pfam05662
85569010927	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
85569010928	trimer interface [polypeptide binding]; other site
85569010929	Coiled stalk of trimeric autotransporter adhesin; Region: YadA_stalk; pfam05662
85569010930	YadA-like C-terminal region; Region: YadA_anchor; pfam03895
85569010931	L-lactate permease; Provisional; Region: PRK10420
85569010932	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
85569010933	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569010934	DNA-binding site [nucleotide binding]; DNA binding site
85569010935	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
85569010936	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
85569010937	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
85569010938	active site
85569010939	substrate binding site [chemical binding]; other site
85569010940	FMN binding site [chemical binding]; other site
85569010941	putative catalytic residues [active]
85569010942	putative rRNA methylase; Provisional; Region: PRK10358
85569010943	Transcriptional regulators [Transcription]; Region: PurR; COG1609
85569010944	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
85569010945	DNA binding site [nucleotide binding]
85569010946	domain linker motif; other site
85569010947	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
85569010948	putative dimerization interface [polypeptide binding]; other site
85569010949	putative ligand binding site [chemical binding]; other site
85569010950	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
85569010951	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
85569010952	active site pocket [active]
85569010953	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569010954	D-galactonate transporter; Region: 2A0114; TIGR00893
85569010955	putative substrate translocation pore; other site
85569010956	serine acetyltransferase; Provisional; Region: cysE; PRK11132
85569010957	Serine acetyltransferase, N-terminal; Region: SATase_N; smart00971
85569010958	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
85569010959	trimer interface [polypeptide binding]; other site
85569010960	active site
85569010961	substrate binding site [chemical binding]; other site
85569010962	CoA binding site [chemical binding]; other site
85569010963	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
85569010964	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
85569010965	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
85569010966	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
85569010967	SecA binding site; other site
85569010968	Preprotein binding site; other site
85569010969	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
85569010970	GSH binding site [chemical binding]; other site
85569010971	catalytic residues [active]
85569010972	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
85569010973	active site residue [active]
85569010974	phosphoglyceromutase; Provisional; Region: PRK05434
85569010975	AmiB activator; Provisional; Region: PRK11637
85569010976	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
85569010977	Peptidase family M23; Region: Peptidase_M23; pfam01551
85569010978	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
85569010979	NodB motif; other site
85569010980	putative active site [active]
85569010981	putative catalytic site [active]
85569010982	Zn binding site [ion binding]; other site
85569010983	putative glycosyl transferase; Provisional; Region: PRK10073
85569010984	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
85569010985	active site
85569010986	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
85569010987	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
85569010988	NAD(P) binding site [chemical binding]; other site
85569010989	8-amino-7-oxononanoate synthase; Region: bioF; TIGR00858
85569010990	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
85569010991	substrate-cofactor binding pocket; other site
85569010992	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569010993	catalytic residue [active]
85569010994	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
85569010995	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
85569010996	NADP binding site [chemical binding]; other site
85569010997	homopentamer interface [polypeptide binding]; other site
85569010998	substrate binding site [chemical binding]; other site
85569010999	active site
85569011000	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
85569011001	putative active site [active]
85569011002	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
85569011003	putative active site [active]
85569011004	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
85569011005	O-antigen ligase RfaL; Provisional; Region: PRK15487
85569011006	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
85569011007	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
85569011008	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; cl17526
85569011009	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
85569011010	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
85569011011	Ligand binding site; other site
85569011012	metal-binding site
85569011013	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
85569011014	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
85569011015	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
85569011016	Ligand binding site; other site
85569011017	metal-binding site
85569011018	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
85569011019	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
85569011020	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
85569011021	putative ADP-binding pocket [chemical binding]; other site
85569011022	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
85569011023	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
85569011024	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
85569011025	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
85569011026	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
85569011027	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
85569011028	putative active site [active]
85569011029	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
85569011030	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
85569011031	Glycosyl transferases group 1; Region: Glycos_transf_1; cl19138
85569011032	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
85569011033	active site
85569011034	(T/H)XGH motif; other site
85569011035	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
85569011036	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
85569011037	DNA binding site [nucleotide binding]
85569011038	catalytic residue [active]
85569011039	H2TH interface [polypeptide binding]; other site
85569011040	putative catalytic residues [active]
85569011041	turnover-facilitating residue; other site
85569011042	intercalation triad [nucleotide binding]; other site
85569011043	8OG recognition residue [nucleotide binding]; other site
85569011044	putative reading head residues; other site
85569011045	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
85569011046	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
85569011047	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
85569011048	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
85569011049	hypothetical protein; Reviewed; Region: PRK00024
85569011050	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
85569011051	MPN+ (JAMM) motif; other site
85569011052	Zinc-binding site [ion binding]; other site
85569011053	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
85569011054	Flavoprotein; Region: Flavoprotein; cl19190
85569011055	DNA / pantothenate metabolizm flavoprotein; Region: DFP; pfam04127
85569011056	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
85569011057	trimer interface [polypeptide binding]; other site
85569011058	active site
85569011059	division inhibitor protein; Provisional; Region: slmA; PRK09480
85569011060	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
85569011061	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
85569011062	active site
85569011063	ribonuclease PH; Reviewed; Region: rph; PRK00173
85569011064	Ribonuclease PH; Region: RNase_PH_bact; cd11362
85569011065	hexamer interface [polypeptide binding]; other site
85569011066	active site
85569011067	hypothetical protein; Provisional; Region: PRK11820
85569011068	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
85569011069	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
85569011070	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569011071	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569011072	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
85569011073	dimerization interface [polypeptide binding]; other site
85569011074	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
85569011075	Predicted membrane protein [Function unknown]; Region: COG2860
85569011076	UPF0126 domain; Region: UPF0126; pfam03458
85569011077	UPF0126 domain; Region: UPF0126; pfam03458
85569011078	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
85569011079	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
85569011080	nucleotide binding pocket [chemical binding]; other site
85569011081	K-X-D-G motif; other site
85569011082	catalytic site [active]
85569011083	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
85569011084	Guanylate kinase; Region: Guanylate_kin; pfam00625
85569011085	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
85569011086	catalytic site [active]
85569011087	G-X2-G-X-G-K; other site
85569011088	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
85569011089	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
85569011090	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
85569011091	Zn2+ binding site [ion binding]; other site
85569011092	Mg2+ binding site [ion binding]; other site
85569011093	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
85569011094	synthetase active site [active]
85569011095	NTP binding site [chemical binding]; other site
85569011096	metal binding site [ion binding]; metal-binding site
85569011097	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
85569011098	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
85569011099	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
85569011100	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
85569011101	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
85569011102	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
85569011103	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
85569011104	generic binding surface II; other site
85569011105	ssDNA binding site; other site
85569011106	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
85569011107	ATP binding site [chemical binding]; other site
85569011108	putative Mg++ binding site [ion binding]; other site
85569011109	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
85569011110	nucleotide binding region [chemical binding]; other site
85569011111	ATP-binding site [chemical binding]; other site
85569011112	Sodium/glutamate symporter; Region: Glt_symporter; cl19414
85569011113	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
85569011114	Sulfate transporter family; Region: Sulfate_transp; cl19250
85569011115	AsmA family; Region: AsmA; pfam05170
85569011116	putative alpha-glucosidase; Provisional; Region: PRK10658
85569011117	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
85569011118	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
85569011119	active site
85569011120	homotrimer interface [polypeptide binding]; other site
85569011121	catalytic site [active]
85569011122	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
85569011123	putative transporter; Provisional; Region: PRK11462
85569011124	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
85569011125	AAA ATPase domain; Region: AAA_15; pfam13175
85569011126	AAA domain; Region: AAA_23; pfam13476
85569011127	Walker A/P-loop; other site
85569011128	ATP binding site [chemical binding]; other site
85569011129	AAA domain; Region: AAA_21; pfam13304
85569011130	Methyltransferase domain; Region: Methyltransf_27; pfam13708
85569011131	Virulence protein [General function prediction only]; Region: COG3943
85569011132	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
85569011133	Transposase; Region: HTH_Tnp_1; cl17663
85569011134	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
85569011135	autotransport protein MisL; Provisional; Region: PRK15313
85569011136	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
85569011137	Autotransporter beta-domain; Region: Autotransporter; pfam03797
85569011138	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
85569011139	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
85569011140	DNA binding site [nucleotide binding]
85569011141	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
85569011142	catalytic triad [active]
85569011143	conserved cis-peptide bond; other site
85569011144	magnesium-transporting ATPase; Provisional; Region: PRK15122
85569011145	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
85569011146	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
85569011147	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
85569011148	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569011149	active site
85569011150	motif I; other site
85569011151	motif II; other site
85569011152	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
85569011153	magnesium transport protein MgtC; Provisional; Region: PRK15385
85569011154	MgtC family; Region: MgtC; pfam02308
85569011155	EamA-like transporter family; Region: EamA; pfam00892
85569011156	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
85569011157	EamA-like transporter family; Region: EamA; pfam00892
85569011158	hypothetical protein; Provisional; Region: PRK09956
85569011159	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
85569011160	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
85569011161	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945
85569011162	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
85569011163	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
85569011164	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
85569011165	active site
85569011166	phosphorylation site [posttranslational modification]
85569011167	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
85569011168	active pocket/dimerization site; other site
85569011169	active site
85569011170	phosphorylation site [posttranslational modification]
85569011171	Predicted transcriptional regulators [Transcription]; Region: ArsR; COG0640
85569011172	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
85569011173	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569011174	Walker A motif; other site
85569011175	ATP binding site [chemical binding]; other site
85569011176	Walker B motif; other site
85569011177	arginine finger; other site
85569011178	Transcriptional antiterminator [Transcription]; Region: COG3933
85569011179	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
85569011180	active site
85569011181	active pocket/dimerization site; other site
85569011182	phosphorylation site [posttranslational modification]
85569011183	PRD domain; Region: PRD; pfam00874
85569011184	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
85569011185	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
85569011186	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
85569011187	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569011188	putative substrate translocation pore; other site
85569011189	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4737
85569011190	Predicted transcriptional regulator [Transcription]; Region: COG2944
85569011191	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569011192	non-specific DNA binding site [nucleotide binding]; other site
85569011193	salt bridge; other site
85569011194	sequence-specific DNA binding site [nucleotide binding]; other site
85569011195	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
85569011196	dimerization domain swap beta strand [polypeptide binding]; other site
85569011197	regulatory protein interface [polypeptide binding]; other site
85569011198	active site
85569011199	regulatory phosphorylation site [posttranslational modification]; other site
85569011200	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
85569011201	intersubunit interface [polypeptide binding]; other site
85569011202	active site
85569011203	zinc binding site [ion binding]; other site
85569011204	Na+ binding site [ion binding]; other site
85569011205	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
85569011206	uncharacterized subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_1; cd07774
85569011207	putative N- and C-terminal domain interface [polypeptide binding]; other site
85569011208	putative active site [active]
85569011209	putative MgATP binding site [chemical binding]; other site
85569011210	catalytic site [active]
85569011211	metal binding site [ion binding]; metal-binding site
85569011212	putative carbohydrate binding site [chemical binding]; other site
85569011213	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
85569011214	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
85569011215	active site
85569011216	P-loop; other site
85569011217	phosphorylation site [posttranslational modification]
85569011218	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
85569011219	active site
85569011220	phosphorylation site [posttranslational modification]
85569011221	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
85569011222	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569011223	DNA-binding site [nucleotide binding]; DNA binding site
85569011224	UTRA domain; Region: UTRA; pfam07702
85569011225	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
85569011226	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
85569011227	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569011228	putative substrate translocation pore; other site
85569011229	regulatory protein UhpC; Provisional; Region: PRK11663
85569011230	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569011231	putative substrate translocation pore; other site
85569011232	sensory histidine kinase UhpB; Provisional; Region: PRK11644
85569011233	MASE1; Region: MASE1; pfam05231
85569011234	Histidine kinase; Region: HisKA_3; pfam07730
85569011235	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569011236	ATP binding site [chemical binding]; other site
85569011237	Mg2+ binding site [ion binding]; other site
85569011238	G-X-G motif; other site
85569011239	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
85569011240	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569011241	active site
85569011242	phosphorylation site [posttranslational modification]
85569011243	intermolecular recognition site; other site
85569011244	dimerization interface [polypeptide binding]; other site
85569011245	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569011246	DNA binding residues [nucleotide binding]
85569011247	dimerization interface [polypeptide binding]; other site
85569011248	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
85569011249	active site
85569011250	catalytic residues [active]
85569011251	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
85569011252	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569011253	putative substrate translocation pore; other site
85569011254	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
85569011255	substrate binding site [chemical binding]; other site
85569011256	dimer interface [polypeptide binding]; other site
85569011257	ATP binding site [chemical binding]; other site
85569011258	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
85569011259	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
85569011260	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
85569011261	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
85569011262	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
85569011263	putative valine binding site [chemical binding]; other site
85569011264	dimer interface [polypeptide binding]; other site
85569011265	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
85569011266	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
85569011267	PYR/PP interface [polypeptide binding]; other site
85569011268	dimer interface [polypeptide binding]; other site
85569011269	TPP binding site [chemical binding]; other site
85569011270	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
85569011271	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
85569011272	TPP-binding site [chemical binding]; other site
85569011273	dimer interface [polypeptide binding]; other site
85569011274	Toxin TisB, type I toxin-antitoxin system; Region: TisB_toxin; pfam13939
85569011275	phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340
85569011276	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
85569011277	EamA-like transporter family; Region: EamA; pfam00892
85569011278	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
85569011279	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569011280	putative substrate translocation pore; other site
85569011281	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
85569011282	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
85569011283	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569011284	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
85569011285	dimerization interface [polypeptide binding]; other site
85569011286	substrate binding pocket [chemical binding]; other site
85569011287	permease DsdX; Provisional; Region: PRK09921
85569011288	GntP family permease; Region: GntP_permease; pfam02447
85569011289	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
85569011290	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
85569011291	catalytic residue [active]
85569011292	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
85569011293	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
85569011294	Domain of unknown function (DUF202); Region: DUF202; pfam02656
85569011295	Predicted membrane protein [Function unknown]; Region: COG2149
85569011296	putative transporter; Validated; Region: PRK03818
85569011297	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
85569011298	TrkA-C domain; Region: TrkA_C; pfam02080
85569011299	TrkA-C domain; Region: TrkA_C; pfam02080
85569011300	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
85569011301	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
85569011302	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
85569011303	putative dimer interface [polypeptide binding]; other site
85569011304	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
85569011305	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
85569011306	putative dimer interface [polypeptide binding]; other site
85569011307	hypothetical protein; Provisional; Region: PRK11616
85569011308	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
85569011309	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
85569011310	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
85569011311	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
85569011312	catalytic residues [active]
85569011313	central insert; other site
85569011314	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
85569011315	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
85569011316	heme exporter protein CcmB; Region: ccmB; TIGR01190
85569011317	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
85569011318	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
85569011319	Walker A/P-loop; other site
85569011320	ATP binding site [chemical binding]; other site
85569011321	Q-loop/lid; other site
85569011322	ABC transporter signature motif; other site
85569011323	Walker B; other site
85569011324	D-loop; other site
85569011325	H-loop/switch region; other site
85569011326	Haem-binding domain; Region: Haem_bd; pfam14376
85569011327	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
85569011328	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
85569011329	chaperone protein TorD; Validated; Region: torD; PRK04976
85569011330	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
85569011331	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
85569011332	molybdopterin cofactor binding site [chemical binding]; other site
85569011333	substrate binding site [chemical binding]; other site
85569011334	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
85569011335	molybdopterin cofactor binding site; other site
85569011336	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
85569011337	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
85569011338	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
85569011339	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569011340	active site
85569011341	phosphorylation site [posttranslational modification]
85569011342	intermolecular recognition site; other site
85569011343	dimerization interface [polypeptide binding]; other site
85569011344	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
85569011345	DNA binding site [nucleotide binding]
85569011346	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
85569011347	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
85569011348	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
85569011349	HAMP domain; Region: HAMP; pfam00672
85569011350	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569011351	dimer interface [polypeptide binding]; other site
85569011352	phosphorylation site [posttranslational modification]
85569011353	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569011354	ATP binding site [chemical binding]; other site
85569011355	Mg2+ binding site [ion binding]; other site
85569011356	G-X-G motif; other site
85569011357	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569011358	active site
85569011359	phosphorylation site [posttranslational modification]
85569011360	intermolecular recognition site; other site
85569011361	dimerization interface [polypeptide binding]; other site
85569011362	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
85569011363	putative binding surface; other site
85569011364	active site
85569011365	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569011366	D-galactonate transporter; Region: 2A0114; TIGR00893
85569011367	putative substrate translocation pore; other site
85569011368	galactonate dehydratase; Provisional; Region: PRK14017
85569011369	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
85569011370	putative active site pocket [active]
85569011371	putative metal binding site [ion binding]; other site
85569011372	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
85569011373	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
85569011374	active site
85569011375	intersubunit interface [polypeptide binding]; other site
85569011376	catalytic residue [active]
85569011377	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
85569011378	Transcriptional regulators [Transcription]; Region: FadR; COG2186
85569011379	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569011380	DNA-binding site [nucleotide binding]; DNA binding site
85569011381	FCD domain; Region: FCD; pfam07729
85569011382	sugar phosphate phosphatase; Provisional; Region: PRK10513
85569011383	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569011384	active site
85569011385	motif I; other site
85569011386	motif II; other site
85569011387	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569011388	D-galactonate transporter; Region: 2A0114; TIGR00893
85569011389	putative substrate translocation pore; other site
85569011390	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
85569011391	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
85569011392	active site pocket [active]
85569011393	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569011394	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569011395	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
85569011396	putative dimerization interface [polypeptide binding]; other site
85569011397	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
85569011398	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569011399	ATP binding site [chemical binding]; other site
85569011400	Mg2+ binding site [ion binding]; other site
85569011401	G-X-G motif; other site
85569011402	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
85569011403	anchoring element; other site
85569011404	dimer interface [polypeptide binding]; other site
85569011405	ATP binding site [chemical binding]; other site
85569011406	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
85569011407	active site
85569011408	putative metal-binding site [ion binding]; other site
85569011409	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
85569011410	recF protein; Region: recf; TIGR00611
85569011411	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569011412	Walker A/P-loop; other site
85569011413	ATP binding site [chemical binding]; other site
85569011414	Q-loop/lid; other site
85569011415	ABC transporter signature motif; other site
85569011416	Walker B; other site
85569011417	D-loop; other site
85569011418	H-loop/switch region; other site
85569011419	DNA polymerase III subunit beta; Validated; Region: PRK05643
85569011420	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
85569011421	putative DNA binding surface [nucleotide binding]; other site
85569011422	dimer interface [polypeptide binding]; other site
85569011423	beta-clamp/clamp loader binding surface; other site
85569011424	beta-clamp/translesion DNA polymerase binding surface; other site
85569011425	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
85569011426	DnaA N-terminal domain; Region: DnaA_N; pfam11638
85569011427	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569011428	Walker A motif; other site
85569011429	ATP binding site [chemical binding]; other site
85569011430	Walker B motif; other site
85569011431	arginine finger; other site
85569011432	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
85569011433	DnaA box-binding interface [nucleotide binding]; other site
85569011434	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
85569011435	ribonuclease P; Reviewed; Region: rnpA; PRK01732
85569011436	hypothetical protein; Validated; Region: PRK00041
85569011437	membrane protein insertase; Provisional; Region: PRK01318
85569011438	YidC periplasmic domain; Region: YidC_periplas; pfam14849
85569011439	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
85569011440	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
85569011441	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
85569011442	trmE is a tRNA modification GTPase; Region: trmE; cd04164
85569011443	G1 box; other site
85569011444	GTP/Mg2+ binding site [chemical binding]; other site
85569011445	Switch I region; other site
85569011446	G2 box; other site
85569011447	Switch II region; other site
85569011448	G3 box; other site
85569011449	G4 box; other site
85569011450	G5 box; other site
85569011451	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
85569011452	Phage integrase SAM-like domain; Region: Phage_int_SAM_5; pfam13102
85569011453	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
85569011454	Int/Topo IB signature motif; other site
85569011455	DNA binding domain, excisionase family; Region: excise; TIGR01764
85569011456	Plasmid encoded RepA protein; Region: RepA_C; pfam04796
85569011457	putative metalloprotease; Provisional; Region: PHA03081
85569011458	Helix-turn-helix domain; Region: HTH_17; pfam12728
85569011459	conjugal transfer mating pair stabilization protein TraN; Provisional; Region: PRK14876
85569011460	Type-1V conjugative transfer system mating pair stabilisation; Region: TraN; cl19475
85569011461	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
85569011462	Conjugative relaxosome accessory transposon protein; Region: TraH; pfam06122
85569011463	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
85569011464	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
85569011465	active site
85569011466	catalytic residues [active]
85569011467	DNA binding site [nucleotide binding]
85569011468	Int/Topo IB signature motif; other site
85569011469	Part of AAA domain; Region: AAA_19; pfam13245
85569011470	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
85569011471	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
85569011472	AAA ATPase domain; Region: AAA_15; pfam13175
85569011473	AAA domain; Region: AAA_23; pfam13476
85569011474	Walker A/P-loop; other site
85569011475	Walker A/P-loop; other site
85569011476	ATP binding site [chemical binding]; other site
85569011477	Q-loop/lid; other site
85569011478	ABC transporter signature motif; other site
85569011479	AAA domain; Region: AAA_21; pfam13304
85569011480	Walker B; other site
85569011481	D-loop; other site
85569011482	H-loop/switch region; other site
85569011483	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
85569011484	putative active site [active]
85569011485	putative metal-binding site [ion binding]; other site
85569011486	Peptidase S8 family domain in Subtilisin-like proteins; Region: Peptidases_S8_Subtilisin_like_2; cd04847
85569011487	Subtilase family; Region: Peptidase_S8; pfam00082
85569011488	active site
85569011489	catalytic triad [active]
85569011490	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569011491	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
85569011492	Walker A motif; other site
85569011493	ATP binding site [chemical binding]; other site
85569011494	Walker B motif; other site
85569011495	arginine finger; other site
85569011496	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
85569011497	multiple promoter invertase; Provisional; Region: mpi; PRK13413
85569011498	catalytic residues [active]
85569011499	catalytic nucleophile [active]
85569011500	Presynaptic Site I dimer interface [polypeptide binding]; other site
85569011501	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
85569011502	Synaptic Flat tetramer interface [polypeptide binding]; other site
85569011503	Synaptic Site I dimer interface [polypeptide binding]; other site
85569011504	DNA binding site [nucleotide binding]
85569011505	Helix-turn-helix domain of Hin and related proteins; Region: HTH_Hin_like; cd00569
85569011506	DNA-binding interface [nucleotide binding]; DNA binding site
85569011507	integrase/recombinase; Provisional; Region: PRK15417
85569011508	IntI (E2) integrases, site-specific tyrosine recombinases, DNA breaking-rejoining enzymes, N- and C-terminal domains. This CD includes integrases which are components of multiresistant integrons and mediate recombination between a proximal attI site and...; Region: INT_IntI; cd01193
85569011509	Int/Topo IB signature motif; other site
85569011510	aminoglycoside resistance protein; Provisional; Region: PRK13746
85569011511	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
85569011512	active site
85569011513	NTP binding site [chemical binding]; other site
85569011514	metal binding triad [ion binding]; metal-binding site
85569011515	antibiotic binding site [chemical binding]; other site
85569011516	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
85569011517	Small Multidrug Resistance protein; Region: Multi_Drug_Res; pfam00893
85569011518	Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  DHPS, a...; Region: Pterin_binding; cl00219
85569011519	Dihydropteroate synthase and related enzymes [Coenzyme metabolism]; Region: FolP; COG0294
85569011520	substrate binding pocket [chemical binding]; other site
85569011521	Protein of unknown function (DUF3363); Region: DUF3363; pfam11843
85569011522	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
85569011523	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569011524	putative substrate translocation pore; other site
85569011525	tetracycline repressor protein TetR; Provisional; Region: PRK13756
85569011526	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
85569011527	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
85569011528	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569011529	putative substrate translocation pore; other site
85569011530	Major Facilitator Superfamily; Region: MFS_1; pfam07690
85569011531	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569011532	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569011533	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
85569011534	dimerization interface [polypeptide binding]; other site
85569011535	substrate binding pocket [chemical binding]; other site
85569011536	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
85569011537	Putative transposase; Region: Y2_Tnp; pfam04986
85569011538	Phage integrase, N-terminal SAM-like domain; Region: Phage_int_SAM_4; pfam13495
85569011539	chaperonin_like superfamily. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. There are 2 main chaperonin groups. The symmetry of type I...; Region: chaperonin_like; cl02777
85569011540	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl19191
85569011541	Small Multidrug Resistance protein; Region: Multi_Drug_Res; pfam00893
85569011542	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
85569011543	Dihydropteroate synthase and related enzymes [Coenzyme metabolism]; Region: FolP; COG0294
85569011544	substrate binding pocket [chemical binding]; other site
85569011545	dimer interface [polypeptide binding]; other site
85569011546	inhibitor binding site; inhibition site
85569011547	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
85569011548	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569011549	Coenzyme A binding pocket [chemical binding]; other site
85569011550	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
85569011551	Integrase core domain; Region: rve; pfam00665
85569011552	Uncharacterized ACR, COG1753; Region: DUF217; cl00762
85569011553	putative transferase, LIC12162 family; Region: o_ant_LIC12162; TIGR04331
85569011554	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
85569011555	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
85569011556	putative active site [active]
85569011557	putative NTP binding site [chemical binding]; other site
85569011558	putative nucleic acid binding site [nucleotide binding]; other site
85569011559	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
85569011560	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569011561	putative substrate translocation pore; other site
85569011562	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
85569011563	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569011564	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
85569011565	substrate binding pocket [chemical binding]; other site
85569011566	dimerization interface [polypeptide binding]; other site
85569011567	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
85569011568	Predicted flavoprotein [General function prediction only]; Region: COG0431
85569011569	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
85569011570	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
85569011571	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569011572	active site
85569011573	motif I; other site
85569011574	motif II; other site
85569011575	transcriptional regulator PhoU; Provisional; Region: PRK11115
85569011576	PhoU domain; Region: PhoU; pfam01895
85569011577	PhoU domain; Region: PhoU; pfam01895
85569011578	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
85569011579	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
85569011580	Walker A/P-loop; other site
85569011581	ATP binding site [chemical binding]; other site
85569011582	Q-loop/lid; other site
85569011583	ABC transporter signature motif; other site
85569011584	Walker B; other site
85569011585	D-loop; other site
85569011586	H-loop/switch region; other site
85569011587	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
85569011588	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569011589	dimer interface [polypeptide binding]; other site
85569011590	conserved gate region; other site
85569011591	putative PBP binding loops; other site
85569011592	ABC-ATPase subunit interface; other site
85569011593	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
85569011594	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569011595	dimer interface [polypeptide binding]; other site
85569011596	conserved gate region; other site
85569011597	putative PBP binding loops; other site
85569011598	ABC-ATPase subunit interface; other site
85569011599	phosphate ABC transporter periplasmic substrate-binding protein PstS; Provisional; Region: PRK10918
85569011600	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
85569011601	substrate binding pocket [chemical binding]; other site
85569011602	membrane-bound complex binding site; other site
85569011603	hinge residues; other site
85569011604	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
85569011605	active site
85569011606	P-loop; other site
85569011607	phosphorylation site [posttranslational modification]
85569011608	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; cl17425
85569011609	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
85569011610	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
85569011611	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
85569011612	shikimate binding site; other site
85569011613	NAD(P) binding site [chemical binding]; other site
85569011614	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
85569011615	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
85569011616	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
85569011617	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
85569011618	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
85569011619	glutaminase active site [active]
85569011620	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
85569011621	dimer interface [polypeptide binding]; other site
85569011622	active site
85569011623	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
85569011624	dimer interface [polypeptide binding]; other site
85569011625	active site
85569011626	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
85569011627	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
85569011628	Substrate binding site; other site
85569011629	Mg++ binding site; other site
85569011630	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
85569011631	active site
85569011632	substrate binding site [chemical binding]; other site
85569011633	CoA binding site [chemical binding]; other site
85569011634	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
85569011635	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
85569011636	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
85569011637	gamma subunit interface [polypeptide binding]; other site
85569011638	epsilon subunit interface [polypeptide binding]; other site
85569011639	LBP interface [polypeptide binding]; other site
85569011640	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
85569011641	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
85569011642	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
85569011643	alpha subunit interaction interface [polypeptide binding]; other site
85569011644	Walker A motif; other site
85569011645	ATP binding site [chemical binding]; other site
85569011646	Walker B motif; other site
85569011647	inhibitor binding site; inhibition site
85569011648	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
85569011649	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
85569011650	core domain interface [polypeptide binding]; other site
85569011651	delta subunit interface [polypeptide binding]; other site
85569011652	epsilon subunit interface [polypeptide binding]; other site
85569011653	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
85569011654	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
85569011655	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
85569011656	beta subunit interaction interface [polypeptide binding]; other site
85569011657	Walker A motif; other site
85569011658	ATP binding site [chemical binding]; other site
85569011659	Walker B motif; other site
85569011660	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
85569011661	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
85569011662	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
85569011663	F0F1 ATP synthase subunit B; Provisional; Region: PRK14471; cl17192
85569011664	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
85569011665	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
85569011666	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
85569011667	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569011668	S-adenosylmethionine binding site [chemical binding]; other site
85569011669	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
85569011670	tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137
85569011671	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
85569011672	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
85569011673	FMN-binding protein MioC; Provisional; Region: PRK09004
85569011674	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
85569011675	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
85569011676	putative DNA binding site [nucleotide binding]; other site
85569011677	putative Zn2+ binding site [ion binding]; other site
85569011678	AsnC family; Region: AsnC_trans_reg; pfam01037
85569011679	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
85569011680	dimer interface [polypeptide binding]; other site
85569011681	active site
85569011682	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2425
85569011683	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
85569011684	metal ion-dependent adhesion site (MIDAS); other site
85569011685	regulatory ATPase RavA; Provisional; Region: PRK13531
85569011686	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569011687	Walker A motif; other site
85569011688	ATP binding site [chemical binding]; other site
85569011689	Walker B motif; other site
85569011690	arginine finger; other site
85569011691	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
85569011692	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
85569011693	D-ribose pyranase; Provisional; Region: PRK11797
85569011694	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
85569011695	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
85569011696	Walker A/P-loop; other site
85569011697	ATP binding site [chemical binding]; other site
85569011698	Q-loop/lid; other site
85569011699	ABC transporter signature motif; other site
85569011700	Walker B; other site
85569011701	D-loop; other site
85569011702	H-loop/switch region; other site
85569011703	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
85569011704	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
85569011705	TM-ABC transporter signature motif; other site
85569011706	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
85569011707	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
85569011708	ligand binding site [chemical binding]; other site
85569011709	dimerization interface [polypeptide binding]; other site
85569011710	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
85569011711	substrate binding site [chemical binding]; other site
85569011712	dimer interface [polypeptide binding]; other site
85569011713	ATP binding site [chemical binding]; other site
85569011714	transcriptional repressor RbsR; Provisional; Region: PRK10423
85569011715	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
85569011716	DNA binding site [nucleotide binding]
85569011717	domain linker motif; other site
85569011718	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
85569011719	dimerization interface [polypeptide binding]; other site
85569011720	ligand binding site [chemical binding]; other site
85569011721	Transcriptional regulators [Transcription]; Region: FadR; COG2186
85569011722	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569011723	DNA-binding site [nucleotide binding]; DNA binding site
85569011724	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
85569011725	transcriptional regulator HdfR; Provisional; Region: PRK03601
85569011726	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569011727	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
85569011728	dimerization interface [polypeptide binding]; other site
85569011729	hypothetical protein; Provisional; Region: PRK11027
85569011730	putative ATP-dependent protease; Provisional; Region: PRK09862
85569011731	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
85569011732	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569011733	Walker A motif; other site
85569011734	ATP binding site [chemical binding]; other site
85569011735	Walker B motif; other site
85569011736	arginine finger; other site
85569011737	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
85569011738	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
85569011739	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
85569011740	PYR/PP interface [polypeptide binding]; other site
85569011741	dimer interface [polypeptide binding]; other site
85569011742	TPP binding site [chemical binding]; other site
85569011743	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
85569011744	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
85569011745	TPP-binding site [chemical binding]; other site
85569011746	dimer interface [polypeptide binding]; other site
85569011747	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
85569011748	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
85569011749	homodimer interface [polypeptide binding]; other site
85569011750	substrate-cofactor binding pocket; other site
85569011751	catalytic residue [active]
85569011752	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
85569011753	threonine dehydratase; Reviewed; Region: PRK09224
85569011754	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
85569011755	tetramer interface [polypeptide binding]; other site
85569011756	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569011757	catalytic residue [active]
85569011758	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
85569011759	putative Ile/Val binding site [chemical binding]; other site
85569011760	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
85569011761	putative Ile/Val binding site [chemical binding]; other site
85569011762	Phage-related protein [Function unknown]; Region: COG4679
85569011763	Uncharacterized conserved small protein [Function unknown]; Region: COG5606
85569011764	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569011765	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
85569011766	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
85569011767	putative dimerization interface [polypeptide binding]; other site
85569011768	ketol-acid reductoisomerase; Validated; Region: PRK05225
85569011769	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
85569011770	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
85569011771	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
85569011772	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
85569011773	Nicotinamide mononucleotide transporter; Region: NMN_transporter; cl01256
85569011774	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
85569011775	Part of AAA domain; Region: AAA_19; pfam13245
85569011776	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
85569011777	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
85569011778	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
85569011779	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
85569011780	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
85569011781	ATP binding site [chemical binding]; other site
85569011782	Mg++ binding site [ion binding]; other site
85569011783	motif III; other site
85569011784	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
85569011785	nucleotide binding region [chemical binding]; other site
85569011786	ATP-binding site [chemical binding]; other site
85569011787	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
85569011788	catalytic residues [active]
85569011789	transcription termination factor Rho; Provisional; Region: rho; PRK09376
85569011790	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
85569011791	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
85569011792	RNA binding site [nucleotide binding]; other site
85569011793	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
85569011794	multimer interface [polypeptide binding]; other site
85569011795	Walker A motif; other site
85569011796	ATP binding site [chemical binding]; other site
85569011797	Walker B motif; other site
85569011798	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Region: ECA_wecA; TIGR02380
85569011799	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
85569011800	Mg++ binding site [ion binding]; other site
85569011801	putative catalytic motif [active]
85569011802	substrate binding site [chemical binding]; other site
85569011803	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
85569011804	Chain length determinant protein; Region: Wzz; pfam02706
85569011805	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
85569011806	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
85569011807	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
85569011808	active site
85569011809	homodimer interface [polypeptide binding]; other site
85569011810	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
85569011811	UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; Region: UDPG_MGDP_dh_N; pfam03721
85569011812	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
85569011813	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
85569011814	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
85569011815	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
85569011816	NAD binding site [chemical binding]; other site
85569011817	substrate binding site [chemical binding]; other site
85569011818	homodimer interface [polypeptide binding]; other site
85569011819	active site
85569011820	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
85569011821	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
85569011822	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
85569011823	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
85569011824	inhibitor-cofactor binding pocket; inhibition site
85569011825	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569011826	catalytic residue [active]
85569011827	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
85569011828	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
85569011829	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
85569011830	putative common antigen polymerase; Provisional; Region: PRK02975
85569011831	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
85569011832	putative transport protein YifK; Provisional; Region: PRK10746
85569011833	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
85569011834	HemY protein N-terminus; Region: HemY_N; pfam07219
85569011835	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
85569011836	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
85569011837	active site
85569011838	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
85569011839	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
85569011840	domain interfaces; other site
85569011841	active site
85569011842	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
85569011843	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
85569011844	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
85569011845	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
85569011846	putative iron binding site [ion binding]; other site
85569011847	Protein of unknown function (DUF3021); Region: DUF3021; pfam11457
85569011848	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
85569011849	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
85569011850	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
85569011851	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
85569011852	hypothetical protein; Provisional; Region: PRK10963
85569011853	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
85569011854	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
85569011855	active site
85569011856	Int/Topo IB signature motif; other site
85569011857	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
85569011858	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
85569011859	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569011860	motif II; other site
85569011861	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
85569011862	Part of AAA domain; Region: AAA_19; pfam13245
85569011863	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
85569011864	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
85569011865	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
85569011866	Cl binding site [ion binding]; other site
85569011867	oligomer interface [polypeptide binding]; other site
85569011868	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
85569011869	hypothetical protein; Provisional; Region: PRK11371
85569011870	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
85569011871	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
85569011872	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
85569011873	Thioesterase-like superfamily; Region: 4HBT_3; pfam13622
85569011874	CoenzymeA binding site [chemical binding]; other site
85569011875	subunit interaction site [polypeptide binding]; other site
85569011876	PHB binding site; other site
85569011877	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
85569011878	dimerization interface [polypeptide binding]; other site
85569011879	substrate binding site [chemical binding]; other site
85569011880	active site
85569011881	calcium binding site [ion binding]; other site
85569011882	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
85569011883	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
85569011884	ATP binding site [chemical binding]; other site
85569011885	putative Mg++ binding site [ion binding]; other site
85569011886	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
85569011887	nucleotide binding region [chemical binding]; other site
85569011888	ATP-binding site [chemical binding]; other site
85569011889	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
85569011890	HRDC domain; Region: HRDC; pfam00570
85569011891	threonine efflux system; Provisional; Region: PRK10229
85569011892	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
85569011893	lysophospholipase L2; Provisional; Region: PRK10749
85569011894	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
85569011895	putative hydrolase; Provisional; Region: PRK10976
85569011896	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569011897	active site
85569011898	motif I; other site
85569011899	motif II; other site
85569011900	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
85569011901	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
85569011902	EamA-like transporter family; Region: EamA; pfam00892
85569011903	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
85569011904	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569011905	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
85569011906	putative dimerization interface [polypeptide binding]; other site
85569011907	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
85569011908	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
85569011909	THF binding site; other site
85569011910	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
85569011911	substrate binding site [chemical binding]; other site
85569011912	THF binding site; other site
85569011913	zinc-binding site [ion binding]; other site
85569011914	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
85569011915	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569011916	FeS/SAM binding site; other site
85569011917	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
85569011918	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
85569011919	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
85569011920	uridine phosphorylase; Provisional; Region: PRK11178
85569011921	DNA recombination protein RmuC; Provisional; Region: PRK10361
85569011922	RmuC family; Region: RmuC; pfam02646
85569011923	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
85569011924	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569011925	S-adenosylmethionine binding site [chemical binding]; other site
85569011926	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
85569011927	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
85569011928	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
85569011929	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
85569011930	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
85569011931	sec-independent translocase; Provisional; Region: PRK01770
85569011932	sec-independent translocase; Provisional; Region: tatB; PRK00404
85569011933	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
85569011934	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
85569011935	active site
85569011936	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
85569011937	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
85569011938	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
85569011939	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
85569011940	FMN reductase; Validated; Region: fre; PRK08051
85569011941	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
85569011942	FAD binding pocket [chemical binding]; other site
85569011943	FAD binding motif [chemical binding]; other site
85569011944	phosphate binding motif [ion binding]; other site
85569011945	beta-alpha-beta structure motif; other site
85569011946	NAD binding pocket [chemical binding]; other site
85569011947	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
85569011948	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
85569011949	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
85569011950	dimer interface [polypeptide binding]; other site
85569011951	active site
85569011952	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
85569011953	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
85569011954	substrate binding site [chemical binding]; other site
85569011955	oxyanion hole (OAH) forming residues; other site
85569011956	trimer interface [polypeptide binding]; other site
85569011957	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
85569011958	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
85569011959	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
85569011960	proline dipeptidase; Provisional; Region: PRK13607
85569011961	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
85569011962	active site
85569011963	hypothetical protein; Provisional; Region: PRK11568
85569011964	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
85569011965	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
85569011966	potassium transporter; Provisional; Region: PRK10750
85569011967	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
85569011968	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
85569011969	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
85569011970	Walker A motif; other site
85569011971	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
85569011972	GTP binding site; other site
85569011973	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
85569011974	serine/threonine protein kinase; Provisional; Region: PRK11768
85569011975	Phosphotransferase enzyme family; Region: APH; pfam01636
85569011976	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
85569011977	catalytic residues [active]
85569011978	hinge region; other site
85569011979	alpha helical domain; other site
85569011980	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
85569011981	putative acyl-acceptor binding pocket; other site
85569011982	DNA polymerase I; Provisional; Region: PRK05755
85569011983	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
85569011984	active site
85569011985	metal binding site 1 [ion binding]; metal-binding site
85569011986	putative 5' ssDNA interaction site; other site
85569011987	metal binding site 3; metal-binding site
85569011988	metal binding site 2 [ion binding]; metal-binding site
85569011989	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
85569011990	putative DNA binding site [nucleotide binding]; other site
85569011991	putative metal binding site [ion binding]; other site
85569011992	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
85569011993	active site
85569011994	catalytic site [active]
85569011995	substrate binding site [chemical binding]; other site
85569011996	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
85569011997	active site
85569011998	DNA binding site [nucleotide binding]
85569011999	catalytic site [active]
85569012000	Predicted GTPase [General function prediction only]; Region: COG0218
85569012001	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
85569012002	G1 box; other site
85569012003	GTP/Mg2+ binding site [chemical binding]; other site
85569012004	Switch I region; other site
85569012005	G2 box; other site
85569012006	G3 box; other site
85569012007	Switch II region; other site
85569012008	G4 box; other site
85569012009	G5 box; other site
85569012010	Vault protein inter-alpha-trypsin domain; Region: VIT; cl02699
85569012011	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
85569012012	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
85569012013	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569012014	FeS/SAM binding site; other site
85569012015	HemN C-terminal domain; Region: HemN_C; pfam06969
85569012016	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
85569012017	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569012018	active site
85569012019	phosphorylation site [posttranslational modification]
85569012020	intermolecular recognition site; other site
85569012021	dimerization interface [polypeptide binding]; other site
85569012022	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569012023	Walker A motif; other site
85569012024	ATP binding site [chemical binding]; other site
85569012025	Walker B motif; other site
85569012026	arginine finger; other site
85569012027	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
85569012028	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
85569012029	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
85569012030	putative active site [active]
85569012031	heme pocket [chemical binding]; other site
85569012032	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569012033	dimer interface [polypeptide binding]; other site
85569012034	phosphorylation site [posttranslational modification]
85569012035	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569012036	ATP binding site [chemical binding]; other site
85569012037	Mg2+ binding site [ion binding]; other site
85569012038	G-X-G motif; other site
85569012039	glutamine synthetase; Provisional; Region: glnA; PRK09469
85569012040	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
85569012041	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
85569012042	GTP-binding protein; Provisional; Region: PRK10218
85569012043	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
85569012044	G1 box; other site
85569012045	putative GEF interaction site [polypeptide binding]; other site
85569012046	GTP/Mg2+ binding site [chemical binding]; other site
85569012047	Switch I region; other site
85569012048	G2 box; other site
85569012049	G3 box; other site
85569012050	Switch II region; other site
85569012051	G4 box; other site
85569012052	G5 box; other site
85569012053	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
85569012054	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
85569012055	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
85569012056	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569012057	active site
85569012058	motif I; other site
85569012059	motif II; other site
85569012060	Radical SAM superfamily; Region: Radical_SAM; pfam04055
85569012061	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569012062	FeS/SAM binding site; other site
85569012063	coproporphyrinogen III oxidase; Validated; Region: PRK08208
85569012064	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569012065	FeS/SAM binding site; other site
85569012066	HemN C-terminal domain; Region: HemN_C; pfam06969
85569012067	Sulfatase; Region: Sulfatase; cl19157
85569012068	ATP-grasp domain; Region: ATP-grasp_4; cl17255
85569012069	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cd00116
85569012070	Leucine-rich repeats; other site
85569012071	Substrate binding site [chemical binding]; other site
85569012072	outer membrane porin L; Provisional; Region: ompL; PRK09980
85569012073	putative symporter YagG; Provisional; Region: PRK09669; cl15392
85569012074	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
85569012075	alpha-glucosidase; Provisional; Region: PRK10426
85569012076	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
85569012077	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
85569012078	putative active site [active]
85569012079	putative catalytic site [active]
85569012080	putative aldose-1-epimerase; Provisional; Region: PRK15172
85569012081	active site
85569012082	catalytic residues [active]
85569012083	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
85569012084	dimerization interface [polypeptide binding]; other site
85569012085	putative active cleft [active]
85569012086	Class I aldolases; Region: Aldolase_Class_I; cd00945
85569012087	catalytic residue [active]
85569012088	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
85569012089	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
85569012090	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833
85569012091	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
85569012092	substrate binding site [chemical binding]; other site
85569012093	ATP binding site [chemical binding]; other site
85569012094	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
85569012095	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
85569012096	putative DNA binding site [nucleotide binding]; other site
85569012097	putative Zn2+ binding site [ion binding]; other site
85569012098	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
85569012099	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
85569012100	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569012101	motif II; other site
85569012102	hypothetical protein; Reviewed; Region: PRK01637
85569012103	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
85569012104	putative active site [active]
85569012105	dimerization interface [polypeptide binding]; other site
85569012106	putative tRNAtyr binding site [nucleotide binding]; other site
85569012107	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569012108	Coenzyme A binding pocket [chemical binding]; other site
85569012109	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
85569012110	Predicted transcription regulator containing HTH domain [Transcription]; Region: COG5499
85569012111	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
85569012112	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569012113	non-specific DNA binding site [nucleotide binding]; other site
85569012114	salt bridge; other site
85569012115	sequence-specific DNA binding site [nucleotide binding]; other site
85569012116	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
85569012117	Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144
85569012118	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
85569012119	Predicted transcriptional regulator [Transcription]; Region: COG2944
85569012120	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569012121	non-specific DNA binding site [nucleotide binding]; other site
85569012122	salt bridge; other site
85569012123	sequence-specific DNA binding site [nucleotide binding]; other site
85569012124	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
85569012125	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
85569012126	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
85569012127	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
85569012128	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
85569012129	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
85569012130	Predicted coiled-coil domain-containing protein (DUF2360); Region: DUF2360; pfam10152
85569012131	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
85569012132	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
85569012133	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
85569012134	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
85569012135	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569012136	non-specific DNA binding site [nucleotide binding]; other site
85569012137	salt bridge; other site
85569012138	sequence-specific DNA binding site [nucleotide binding]; other site
85569012139	Cupin domain; Region: Cupin_2; cl17218
85569012140	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
85569012141	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
85569012142	dimer interface [polypeptide binding]; other site
85569012143	active site
85569012144	metal binding site [ion binding]; metal-binding site
85569012145	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
85569012146	intersubunit interface [polypeptide binding]; other site
85569012147	active site
85569012148	Zn2+ binding site [ion binding]; other site
85569012149	L-rhamnose isomerase; Provisional; Region: PRK01076
85569012150	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
85569012151	N- and C-terminal domain interface [polypeptide binding]; other site
85569012152	active site
85569012153	putative catalytic site [active]
85569012154	metal binding site [ion binding]; metal-binding site
85569012155	ATP binding site [chemical binding]; other site
85569012156	rhamnulokinase; Provisional; Region: rhaB; PRK10640
85569012157	carbohydrate binding site [chemical binding]; other site
85569012158	transcriptional activator RhaS; Provisional; Region: PRK13503
85569012159	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
85569012160	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569012161	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569012162	transcriptional activator RhaR; Provisional; Region: PRK13502
85569012163	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
85569012164	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569012165	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569012166	L-rhamnose-proton symport protein (RhaT); Region: RhaT; pfam06379
85569012167	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; pfam06178
85569012168	Transposase IS200 like; Region: Y1_Tnp; pfam01797
85569012169	DctM-like transporters; Region: DctM; pfam06808
85569012170	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
85569012171	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
85569012172	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
85569012173	superoxide dismutase; Provisional; Region: PRK10925
85569012174	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
85569012175	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
85569012176	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
85569012177	MOSC domain; Region: MOSC; pfam03473
85569012178	3-alpha domain; Region: 3-alpha; pfam03475
85569012179	SnoaL-like domain; Region: SnoaL_2; pfam12680
85569012180	two-component sensor protein; Provisional; Region: cpxA; PRK09470
85569012181	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569012182	dimerization interface [polypeptide binding]; other site
85569012183	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569012184	dimer interface [polypeptide binding]; other site
85569012185	phosphorylation site [posttranslational modification]
85569012186	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569012187	ATP binding site [chemical binding]; other site
85569012188	Mg2+ binding site [ion binding]; other site
85569012189	G-X-G motif; other site
85569012190	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
85569012191	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569012192	active site
85569012193	intermolecular recognition site; other site
85569012194	dimerization interface [polypeptide binding]; other site
85569012195	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
85569012196	DNA binding site [nucleotide binding]
85569012197	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
85569012198	dimer interface [polypeptide binding]; other site
85569012199	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
85569012200	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
85569012201	active site
85569012202	ADP/pyrophosphate binding site [chemical binding]; other site
85569012203	dimerization interface [polypeptide binding]; other site
85569012204	allosteric effector site; other site
85569012205	fructose-1,6-bisphosphate binding site; other site
85569012206	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
85569012207	substrate binding pocket [chemical binding]; other site
85569012208	membrane-bound complex binding site; other site
85569012209	hinge residues; other site
85569012210	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
85569012211	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
85569012212	putative symporter YagG; Provisional; Region: PRK09669; cl15392
85569012213	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
85569012214	putative substrate binding site [chemical binding]; other site
85569012215	putative ATP binding site [chemical binding]; other site
85569012216	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
85569012217	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
85569012218	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569012219	DNA-binding site [nucleotide binding]; DNA binding site
85569012220	Alanine racemase, C-terminal domain; Region: Ala_racemase_C; cl08293
85569012221	UTRA domain; Region: UTRA; pfam07702
85569012222	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
85569012223	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
85569012224	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
85569012225	putative N- and C-terminal domain interface [polypeptide binding]; other site
85569012226	putative active site [active]
85569012227	putative MgATP binding site [chemical binding]; other site
85569012228	catalytic site [active]
85569012229	metal binding site [ion binding]; metal-binding site
85569012230	putative carbohydrate binding site [chemical binding]; other site
85569012231	transcriptional regulator LsrR; Provisional; Region: PRK15418
85569012232	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
85569012233	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
85569012234	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
85569012235	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
85569012236	Walker A/P-loop; other site
85569012237	ATP binding site [chemical binding]; other site
85569012238	Q-loop/lid; other site
85569012239	ABC transporter signature motif; other site
85569012240	Walker B; other site
85569012241	D-loop; other site
85569012242	H-loop/switch region; other site
85569012243	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
85569012244	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
85569012245	TM-ABC transporter signature motif; other site
85569012246	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
85569012247	TM-ABC transporter signature motif; other site
85569012248	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
85569012249	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
85569012250	ligand binding site [chemical binding]; other site
85569012251	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
85569012252	putative active site; other site
85569012253	catalytic residue [active]
85569012254	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
85569012255	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
85569012256	substrate binding site [chemical binding]; other site
85569012257	hexamer interface [polypeptide binding]; other site
85569012258	metal binding site [ion binding]; metal-binding site
85569012259	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
85569012260	substrate binding site [chemical binding]; other site
85569012261	dimer interface [polypeptide binding]; other site
85569012262	catalytic triad [active]
85569012263	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
85569012264	Predicted membrane protein [Function unknown]; Region: COG3152
85569012265	ferredoxin-NADP reductase; Provisional; Region: PRK10926
85569012266	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
85569012267	FAD binding pocket [chemical binding]; other site
85569012268	FAD binding motif [chemical binding]; other site
85569012269	phosphate binding motif [ion binding]; other site
85569012270	beta-alpha-beta structure motif; other site
85569012271	NAD binding pocket [chemical binding]; other site
85569012272	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
85569012273	putative active site [active]
85569012274	glycerol kinase; Provisional; Region: glpK; PRK00047
85569012275	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
85569012276	N- and C-terminal domain interface [polypeptide binding]; other site
85569012277	active site
85569012278	MgATP binding site [chemical binding]; other site
85569012279	catalytic site [active]
85569012280	metal binding site [ion binding]; metal-binding site
85569012281	glycerol binding site [chemical binding]; other site
85569012282	homotetramer interface [polypeptide binding]; other site
85569012283	homodimer interface [polypeptide binding]; other site
85569012284	FBP binding site [chemical binding]; other site
85569012285	protein IIAGlc interface [polypeptide binding]; other site
85569012286	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
85569012287	amphipathic channel; other site
85569012288	Asn-Pro-Ala signature motifs; other site
85569012289	septal ring assembly protein ZapB; Provisional; Region: PRK15422
85569012290	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
85569012291	1,4-Dihydroxy-2-naphthoate octaprenyltransferase; Region: PT_UbiA_UBIAD1; cd13962
85569012292	putative active site [active]
85569012293	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
85569012294	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569012295	Walker A motif; other site
85569012296	ATP binding site [chemical binding]; other site
85569012297	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569012298	Walker B motif; other site
85569012299	arginine finger; other site
85569012300	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
85569012301	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
85569012302	active site
85569012303	HslU subunit interaction site [polypeptide binding]; other site
85569012304	essential cell division protein FtsN; Provisional; Region: PRK10927
85569012305	Sporulation related domain; Region: SPOR; pfam05036
85569012306	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
85569012307	DNA binding site [nucleotide binding]
85569012308	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
85569012309	domain linker motif; other site
85569012310	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
85569012311	dimerization interface [polypeptide binding]; other site
85569012312	ligand binding site [chemical binding]; other site
85569012313	primosome assembly protein PriA; Validated; Region: PRK05580
85569012314	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
85569012315	ATP binding site [chemical binding]; other site
85569012316	putative Mg++ binding site [ion binding]; other site
85569012317	helicase superfamily c-terminal domain; Region: HELICc; smart00490
85569012318	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
85569012319	conserved hypothetical protein; Region: chp_urease_rgn; TIGR02117
85569012320	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
85569012321	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
85569012322	dimerization interface [polypeptide binding]; other site
85569012323	DNA binding site [nucleotide binding]
85569012324	corepressor binding sites; other site
85569012325	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
85569012326	homodimer interface [polypeptide binding]; other site
85569012327	substrate-cofactor binding pocket; other site
85569012328	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569012329	catalytic residue [active]
85569012330	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
85569012331	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
85569012332	putative catalytic residues [active]
85569012333	putative nucleotide binding site [chemical binding]; other site
85569012334	putative aspartate binding site [chemical binding]; other site
85569012335	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
85569012336	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
85569012337	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
85569012338	mechanosensitive channel MscS; Provisional; Region: PRK10334
85569012339	Conserved TM helix; Region: TM_helix; pfam05552
85569012340	Mechanosensitive ion channel; Region: MS_channel; pfam00924
85569012341	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
85569012342	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
85569012343	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
85569012344	active site
85569012345	metal binding site [ion binding]; metal-binding site
85569012346	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
85569012347	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
85569012348	FAD binding site [chemical binding]; other site
85569012349	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
85569012350	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
85569012351	heme binding site [chemical binding]; other site
85569012352	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
85569012353	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
85569012354	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
85569012355	dimer interface [polypeptide binding]; other site
85569012356	active site
85569012357	metal binding site [ion binding]; metal-binding site
85569012358	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
85569012359	active site
85569012360	intersubunit interactions; other site
85569012361	catalytic residue [active]
85569012362	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
85569012363	dimerization domain swap beta strand [polypeptide binding]; other site
85569012364	regulatory protein interface [polypeptide binding]; other site
85569012365	active site
85569012366	regulatory phosphorylation site [posttranslational modification]; other site
85569012367	PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524
85569012368	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
85569012369	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
85569012370	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
85569012371	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
85569012372	active site
85569012373	phosphorylation site [posttranslational modification]
85569012374	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
85569012375	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
85569012376	active site
85569012377	P-loop; other site
85569012378	phosphorylation site [posttranslational modification]
85569012379	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
85569012380	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
85569012381	dimer interface [polypeptide binding]; other site
85569012382	active site
85569012383	glycine loop; other site
85569012384	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
85569012385	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569012386	FeS/SAM binding site; other site
85569012387	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
85569012388	active site
85569012389	P-loop; other site
85569012390	phosphorylation site [posttranslational modification]
85569012391	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569012392	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
85569012393	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569012394	hypothetical protein; Provisional; Region: PRK10649
85569012395	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
85569012396	Sulfatase; Region: Sulfatase; pfam00884
85569012397	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
85569012398	acetylornithine deacetylase (ArgE); Region: AcOrn-deacetyl; TIGR01892
85569012399	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
85569012400	metal binding site [ion binding]; metal-binding site
85569012401	putative dimer interface [polypeptide binding]; other site
85569012402	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
85569012403	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118
85569012404	Semialdehyde dehydrogenase, dimerization domain; Region: Semialdhyde_dhC; pfam02774
85569012405	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
85569012406	nucleotide binding site [chemical binding]; other site
85569012407	N-acetyl-L-glutamate binding site [chemical binding]; other site
85569012408	argininosuccinate lyase; Provisional; Region: PRK04833
85569012409	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
85569012410	active sites [active]
85569012411	tetramer interface [polypeptide binding]; other site
85569012412	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
85569012413	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569012414	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
85569012415	dimerization interface [polypeptide binding]; other site
85569012416	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
85569012417	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
85569012418	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
85569012419	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
85569012420	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
85569012421	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
85569012422	hypothetical protein; Provisional; Region: PRK11056
85569012423	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
85569012424	Protein of unknown function (DUF3164); Region: DUF3164; pfam11363
85569012425	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569012426	S-adenosylmethionine binding site [chemical binding]; other site
85569012427	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
85569012428	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
85569012429	N-terminal plug; other site
85569012430	ligand-binding site [chemical binding]; other site
85569012431	glutamate racemase; Provisional; Region: PRK00865
85569012432	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
85569012433	FAD binding domain; Region: FAD_binding_4; pfam01565
85569012434	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
85569012435	Biotin operon repressor [Transcription]; Region: BirA; COG1654
85569012436	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
85569012437	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
85569012438	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
85569012439	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
85569012440	ATP-binding site [chemical binding]; other site
85569012441	CoA-binding site [chemical binding]; other site
85569012442	Mg2+-binding site [ion binding]; other site
85569012443	elongation factor Tu; Reviewed; Region: PRK00049
85569012444	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
85569012445	G1 box; other site
85569012446	GEF interaction site [polypeptide binding]; other site
85569012447	GTP/Mg2+ binding site [chemical binding]; other site
85569012448	Switch I region; other site
85569012449	G2 box; other site
85569012450	G3 box; other site
85569012451	Switch II region; other site
85569012452	G4 box; other site
85569012453	G5 box; other site
85569012454	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
85569012455	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
85569012456	Antibiotic Binding Site [chemical binding]; other site
85569012457	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
85569012458	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
85569012459	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
85569012460	putative homodimer interface [polypeptide binding]; other site
85569012461	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
85569012462	heterodimer interface [polypeptide binding]; other site
85569012463	homodimer interface [polypeptide binding]; other site
85569012464	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
85569012465	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
85569012466	23S rRNA interface [nucleotide binding]; other site
85569012467	L7/L12 interface [polypeptide binding]; other site
85569012468	putative thiostrepton binding site; other site
85569012469	L25 interface [polypeptide binding]; other site
85569012470	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
85569012471	mRNA/rRNA interface [nucleotide binding]; other site
85569012472	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
85569012473	23S rRNA interface [nucleotide binding]; other site
85569012474	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
85569012475	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
85569012476	core dimer interface [polypeptide binding]; other site
85569012477	peripheral dimer interface [polypeptide binding]; other site
85569012478	L10 interface [polypeptide binding]; other site
85569012479	L11 interface [polypeptide binding]; other site
85569012480	putative EF-Tu interaction site [polypeptide binding]; other site
85569012481	putative EF-G interaction site [polypeptide binding]; other site
85569012482	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
85569012483	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
85569012484	RPB12 interaction site [polypeptide binding]; other site
85569012485	RNA polymerase beta subunit; Region: RNA_pol_Rpb2_1; cl19478
85569012486	RPB1 interaction site [polypeptide binding]; other site
85569012487	RNA polymerase beta subunit external 1 domain; Region: RNA_pol_Rpb2_45; pfam10385
85569012488	RPB10 interaction site [polypeptide binding]; other site
85569012489	RPB11 interaction site [polypeptide binding]; other site
85569012490	RPB3 interaction site [polypeptide binding]; other site
85569012491	Largest subunit (beta') of bacterial DNA-dependent RNA polymerase (RNAP), N-terminal domain; Region: RNAP_beta'_N; cd01609
85569012492	beta and beta' interface [polypeptide binding]; other site
85569012493	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
85569012494	beta' and sigma factor interface [polypeptide binding]; other site
85569012495	Zn-binding [ion binding]; other site
85569012496	active site region [active]
85569012497	catalytic site [active]
85569012498	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
85569012499	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
85569012500	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
85569012501	G-loop; other site
85569012502	DNA binding site [nucleotide binding]
85569012503	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
85569012504	type III secretion system protein; Provisional; Region: PRK15384
85569012505	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
85569012506	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569012507	FeS/SAM binding site; other site
85569012508	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
85569012509	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
85569012510	ThiS interaction site; other site
85569012511	putative active site [active]
85569012512	tetramer interface [polypeptide binding]; other site
85569012513	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
85569012514	thiS-thiF/thiG interaction site; other site
85569012515	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
85569012516	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
85569012517	ATP binding site [chemical binding]; other site
85569012518	substrate interface [chemical binding]; other site
85569012519	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
85569012520	thiamine phosphate binding site [chemical binding]; other site
85569012521	active site
85569012522	pyrophosphate binding site [ion binding]; other site
85569012523	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
85569012524	ThiC-associated domain; Region: ThiC-associated; pfam13667
85569012525	ThiC family; Region: ThiC; pfam01964
85569012526	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
85569012527	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
85569012528	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
85569012529	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
85569012530	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
85569012531	putative NADH binding site [chemical binding]; other site
85569012532	putative active site [active]
85569012533	nudix motif; other site
85569012534	putative metal binding site [ion binding]; other site
85569012535	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
85569012536	substrate binding site [chemical binding]; other site
85569012537	active site
85569012538	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
85569012539	Active_site [active]
85569012540	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
85569012541	histone-like DNA-binding protein HU; Region: HU; cd13831
85569012542	dimer interface [polypeptide binding]; other site
85569012543	DNA binding site [nucleotide binding]
85569012544	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
85569012545	zinc resistance protein; Provisional; Region: zraP; PRK11546
85569012546	dimer interface [polypeptide binding]; other site
85569012547	sensor protein ZraS; Provisional; Region: PRK10364
85569012548	Sensory domain of two-component sensor kinase; Region: Cache_3; pfam14827
85569012549	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569012550	dimer interface [polypeptide binding]; other site
85569012551	phosphorylation site [posttranslational modification]
85569012552	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569012553	ATP binding site [chemical binding]; other site
85569012554	Mg2+ binding site [ion binding]; other site
85569012555	G-X-G motif; other site
85569012556	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
85569012557	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569012558	active site
85569012559	phosphorylation site [posttranslational modification]
85569012560	intermolecular recognition site; other site
85569012561	dimerization interface [polypeptide binding]; other site
85569012562	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569012563	Walker A motif; other site
85569012564	ATP binding site [chemical binding]; other site
85569012565	Walker B motif; other site
85569012566	arginine finger; other site
85569012567	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
85569012568	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
85569012569	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
85569012570	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
85569012571	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
85569012572	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
85569012573	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
85569012574	purine monophosphate binding site [chemical binding]; other site
85569012575	dimer interface [polypeptide binding]; other site
85569012576	putative catalytic residues [active]
85569012577	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
85569012578	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
85569012579	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569012580	Coenzyme A binding pocket [chemical binding]; other site
85569012581	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
85569012582	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
85569012583	proposed active site lysine [active]
85569012584	conserved cys residue [active]
85569012585	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
85569012586	active site
85569012587	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
85569012588	tetramer interface [polypeptide binding]; other site
85569012589	active site
85569012590	Mg2+/Mn2+ binding site [ion binding]; other site
85569012591	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
85569012592	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
85569012593	transcriptional repressor IclR; Provisional; Region: PRK11569
85569012594	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
85569012595	Bacterial transcriptional regulator; Region: IclR; pfam01614
85569012596	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
85569012597	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
85569012598	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
85569012599	substrate binding pocket [chemical binding]; other site
85569012600	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
85569012601	B12 binding site [chemical binding]; other site
85569012602	cobalt ligand [ion binding]; other site
85569012603	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
85569012604	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
85569012605	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
85569012606	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
85569012607	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
85569012608	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
85569012609	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
85569012610	RNA binding surface [nucleotide binding]; other site
85569012611	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
85569012612	probable active site [active]
85569012613	hypothetical protein; Provisional; Region: PRK10515
85569012614	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
85569012615	Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045
85569012616	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
85569012617	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
85569012618	Phage-related tail fibre protein [General function prediction only]; Region: COG5301
85569012619	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
85569012620	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
85569012621	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
85569012622	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
85569012623	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
85569012624	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
85569012625	Phage-related baseplate assembly protein [General function prediction only]; Region: COG3948
85569012626	Phage baseplate assembly protein W [General function prediction only]; Region: COG3628
85569012627	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
85569012628	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
85569012629	Ligand binding site; other site
85569012630	Putative Catalytic site; other site
85569012631	DXD motif; other site
85569012632	Predicted membrane protein [Function unknown]; Region: COG2246
85569012633	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
85569012634	Phage protein D [General function prediction only]; Region: COG3500
85569012635	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
85569012636	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
85569012637	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
85569012638	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
85569012639	Phage tail tube protein FII [General function prediction only]; Region: COG3498
85569012640	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
85569012641	Gp37 protein; Region: Gp37; pfam09646
85569012642	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
85569012643	N-acetyl-D-glucosamine binding site [chemical binding]; other site
85569012644	catalytic residue [active]
85569012645	Protein of unknown function (DUF4063); Region: DUF4063; pfam13272
85569012646	Uncharacterized conserved protein [Function unknown]; Region: COG5566
85569012647	aspartate kinase III; Validated; Region: PRK09084
85569012648	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
85569012649	nucleotide binding site [chemical binding]; other site
85569012650	substrate binding site [chemical binding]; other site
85569012651	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
85569012652	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
85569012653	dimer interface [polypeptide binding]; other site
85569012654	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
85569012655	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
85569012656	active site
85569012657	dimer interface [polypeptide binding]; other site
85569012658	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
85569012659	dimer interface [polypeptide binding]; other site
85569012660	active site
85569012661	Exopolysaccharide production protein YjbE; Region: YjbE; pfam11106
85569012662	Group 4 capsule polysaccharide formation lipoprotein gfcB; Region: Cap_synth_GfcB; pfam11102
85569012663	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
85569012664	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
85569012665	Predicted membrane protein [Function unknown]; Region: COG3223
85569012666	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
85569012667	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569012668	dimer interface [polypeptide binding]; other site
85569012669	conserved gate region; other site
85569012670	putative PBP binding loops; other site
85569012671	ABC-ATPase subunit interface; other site
85569012672	maltose transporter membrane protein; Provisional; Region: malF; PRK10999
85569012673	Maltose transport system permease protein MalF P2 domain; Region: MalF_P2; pfam14785
85569012674	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
85569012675	dimer interface [polypeptide binding]; other site
85569012676	conserved gate region; other site
85569012677	putative PBP binding loops; other site
85569012678	ABC-ATPase subunit interface; other site
85569012679	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
85569012680	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
85569012681	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
85569012682	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
85569012683	Walker A/P-loop; other site
85569012684	ATP binding site [chemical binding]; other site
85569012685	Q-loop/lid; other site
85569012686	ABC transporter signature motif; other site
85569012687	Walker B; other site
85569012688	D-loop; other site
85569012689	H-loop/switch region; other site
85569012690	TOBE domain; Region: TOBE_2; pfam08402
85569012691	maltoporin; Provisional; Region: lamB; PRK09360
85569012692	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
85569012693	trimer interface; other site
85569012694	sugar binding site [chemical binding]; other site
85569012695	maltose regulon periplasmic protein; Provisional; Region: PRK10564
85569012696	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
85569012697	4-Hydroxybenzoate polyprenyltransferase; Region: PT_UbiA_COQ2; cd13959
85569012698	putative active site [active]
85569012699	Glycerol-3-phosphate O-acyltransferase [Lipid metabolism]; Region: PlsB; COG2937
85569012700	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
85569012701	putative acyl-acceptor binding pocket; other site
85569012702	Integral membrane diacylglycerol kinase; Region: DAGK_IM; cd14264
85569012703	putative active site [active]
85569012704	trimer interface [polypeptide binding]; other site
85569012705	putative active site [active]
85569012706	Zn binding site [ion binding]; other site
85569012707	LexA repressor; Validated; Region: PRK00215
85569012708	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
85569012709	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
85569012710	Catalytic site [active]
85569012711	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
85569012712	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
85569012713	hypothetical protein; Provisional; Region: PRK10428
85569012714	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
85569012715	metal binding site 2 [ion binding]; metal-binding site
85569012716	putative DNA binding helix; other site
85569012717	metal binding site 1 [ion binding]; metal-binding site
85569012718	dimer interface [polypeptide binding]; other site
85569012719	structural Zn2+ binding site [ion binding]; other site
85569012720	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
85569012721	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
85569012722	Dihydrouridine synthase (Dus); Region: Dus; pfam01207
85569012723	FMN binding site [chemical binding]; other site
85569012724	active site
85569012725	catalytic residues [active]
85569012726	substrate binding site [chemical binding]; other site
85569012727	phage shock protein G; Reviewed; Region: pspG; PRK09459
85569012728	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
85569012729	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
85569012730	NADP binding site [chemical binding]; other site
85569012731	dimer interface [polypeptide binding]; other site
85569012732	replicative DNA helicase; Provisional; Region: PRK08006
85569012733	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
85569012734	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
85569012735	Walker A motif; other site
85569012736	ATP binding site [chemical binding]; other site
85569012737	Walker B motif; other site
85569012738	DNA binding loops [nucleotide binding]
85569012739	alanine racemase; Reviewed; Region: alr; PRK00053
85569012740	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
85569012741	active site
85569012742	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
85569012743	substrate binding site [chemical binding]; other site
85569012744	catalytic residues [active]
85569012745	dimer interface [polypeptide binding]; other site
85569012746	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
85569012747	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
85569012748	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569012749	homodimer interface [polypeptide binding]; other site
85569012750	catalytic residue [active]
85569012751	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
85569012752	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569012753	active site
85569012754	motif I; other site
85569012755	motif II; other site
85569012756	Uncharacterized conserved protein [Function unknown]; Region: COG0432
85569012757	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
85569012758	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
85569012759	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
85569012760	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
85569012761	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
85569012762	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
85569012763	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
85569012764	dimer interface [polypeptide binding]; other site
85569012765	ssDNA binding site [nucleotide binding]; other site
85569012766	tetramer (dimer of dimers) interface [polypeptide binding]; other site
85569012767	putative single-stranded DNA-binding protein; Region: PHA01740
85569012768	hypothetical protein; Validated; Region: PRK09039
85569012769	Zinc finger-containing protein; Region: zf-C4H2; pfam10146
85569012770	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
85569012771	Outer membrane efflux protein; Region: OEP; pfam02321
85569012772	Outer membrane efflux protein; Region: OEP; pfam02321
85569012773	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
85569012774	Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169
85569012775	HlyD family secretion protein; Region: HlyD_3; pfam13437
85569012776	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
85569012777	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012778	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012779	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
85569012780	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012781	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012782	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012783	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
85569012784	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
85569012785	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012786	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
85569012787	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
85569012788	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012789	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
85569012790	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012791	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
85569012792	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
85569012793	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012794	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
85569012795	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012796	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
85569012797	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
85569012798	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012799	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
85569012800	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012801	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
85569012802	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
85569012803	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012804	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012805	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012806	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
85569012807	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012808	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012809	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012810	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012811	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012812	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012813	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012814	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
85569012815	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012816	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012817	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
85569012818	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012819	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012820	Bacterial Ig-like domain (group 3); Region: Big_3_2; pfam12245
85569012821	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012822	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012823	Bacterial Ig-like domain (group 3); Region: Big_3_3; pfam13750
85569012824	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
85569012825	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012826	Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754
85569012827	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
85569012828	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
85569012829	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569012830	Walker A/P-loop; other site
85569012831	ATP binding site [chemical binding]; other site
85569012832	Q-loop/lid; other site
85569012833	ABC transporter signature motif; other site
85569012834	Walker B; other site
85569012835	D-loop; other site
85569012836	H-loop/switch region; other site
85569012837	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
85569012838	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
85569012839	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
85569012840	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
85569012841	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569012842	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
85569012843	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
85569012844	DNA binding residues [nucleotide binding]
85569012845	dimer interface [polypeptide binding]; other site
85569012846	[2Fe-2S] cluster binding site [ion binding]; other site
85569012847	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
85569012848	GST_N family, Saccharomyces cerevisiae GTT1-like subfamily; composed of predominantly uncharacterized proteins with similarity to the S. cerevisiae GST protein, GTT1, and the Schizosaccharomyces pombe GST-III. GSTs are cytosolic dimeric proteins involved...; Region: GST_N_GTT1_like; cd03046
85569012849	putative C-terminal domain interface [polypeptide binding]; other site
85569012850	putative GSH binding site (G-site) [chemical binding]; other site
85569012851	putative dimer interface [polypeptide binding]; other site
85569012852	C-terminal, alpha helical domain of GTT1-like Glutathione S-transferases; Region: GST_C_GTT1_like; cd03189
85569012853	putative N-terminal domain interface [polypeptide binding]; other site
85569012854	putative dimer interface [polypeptide binding]; other site
85569012855	putative substrate binding pocket (H-site) [chemical binding]; other site
85569012856	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
85569012857	Sulfate transporter family; Region: Sulfate_transp; cl19250
85569012858	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
85569012859	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
85569012860	Transcriptional regulator [Transcription]; Region: LysR; COG0583
85569012861	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569012862	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
85569012863	putative dimerization interface [polypeptide binding]; other site
85569012864	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
85569012865	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
85569012866	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
85569012867	Na binding site [ion binding]; other site
85569012868	Predicted membrane protein [Function unknown]; Region: COG3162
85569012869	acetyl-CoA synthetase; Provisional; Region: PRK00174
85569012870	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
85569012871	active site
85569012872	CoA binding site [chemical binding]; other site
85569012873	acyl-activating enzyme (AAE) consensus motif; other site
85569012874	AMP binding site [chemical binding]; other site
85569012875	acetate binding site [chemical binding]; other site
85569012876	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
85569012877	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
85569012878	Cytochrome c3; Region: Cytochrom_c3_2; pfam14537
85569012879	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
85569012880	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
85569012881	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
85569012882	heme lyase subunit NrfE; Provisional; Region: PRK10369
85569012883	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
85569012884	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
85569012885	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
85569012886	binding surface
85569012887	TPR motif; other site
85569012888	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
85569012889	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
85569012890	Sel1-like repeats; Region: SEL1; smart00671
85569012891	Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555
85569012892	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569012893	Coenzyme A binding pocket [chemical binding]; other site
85569012894	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
85569012895	dimer interface [polypeptide binding]; other site
85569012896	hypothetical protein; Provisional; Region: PRK10220
85569012897	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
85569012898	PhnA protein; Region: PhnA; pfam03831
85569012899	proline/glycine betaine transporter; Provisional; Region: PRK10642
85569012900	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569012901	putative substrate translocation pore; other site
85569012902	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
85569012903	sensor protein BasS/PmrB; Provisional; Region: PRK10755
85569012904	HAMP domain; Region: HAMP; pfam00672
85569012905	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569012906	dimer interface [polypeptide binding]; other site
85569012907	phosphorylation site [posttranslational modification]
85569012908	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569012909	ATP binding site [chemical binding]; other site
85569012910	Mg2+ binding site [ion binding]; other site
85569012911	G-X-G motif; other site
85569012912	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
85569012913	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569012914	active site
85569012915	phosphorylation site [posttranslational modification]
85569012916	intermolecular recognition site; other site
85569012917	dimerization interface [polypeptide binding]; other site
85569012918	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
85569012919	DNA binding site [nucleotide binding]
85569012920	putative metal dependent hydrolase; Provisional; Region: PRK11598
85569012921	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
85569012922	Sulfatase; Region: Sulfatase; pfam00884
85569012923	arginine:agmatin antiporter; Provisional; Region: PRK10644
85569012924	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569012925	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
85569012926	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569012927	arginine decarboxylase; Provisional; Region: PRK15029
85569012928	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
85569012929	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
85569012930	homodimer interface [polypeptide binding]; other site
85569012931	pyridoxal 5'-phosphate binding site [chemical binding]; other site
85569012932	catalytic residue [active]
85569012933	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
85569012934	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
85569012935	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569012936	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569012937	alpha-galactosidase; Provisional; Region: PRK15076
85569012938	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
85569012939	NAD binding site [chemical binding]; other site
85569012940	sugar binding site [chemical binding]; other site
85569012941	divalent metal binding site [ion binding]; other site
85569012942	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
85569012943	dimer interface [polypeptide binding]; other site
85569012944	melibiose:sodium symporter; Provisional; Region: PRK10429
85569012945	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
85569012946	fumarate hydratase; Provisional; Region: PRK15389
85569012947	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
85569012948	Fumarase C-terminus; Region: Fumerase_C; pfam05683
85569012949	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
85569012950	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
85569012951	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569012952	active site
85569012953	phosphorylation site [posttranslational modification]
85569012954	intermolecular recognition site; other site
85569012955	dimerization interface [polypeptide binding]; other site
85569012956	sensory histidine kinase DcuS; Provisional; Region: PRK11086
85569012957	Sensory domain of two-component sensor kinase; Region: Cache_3; pfam14827
85569012958	PAS domain; Region: PAS; smart00091
85569012959	Signal transduction histidine kinase; Region: H_kinase_N; pfam12282
85569012960	Sensor_kinase_SpoOB-type, alpha-helical domain; Region: SPOB_a; pfam14689
85569012961	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569012962	ATP binding site [chemical binding]; other site
85569012963	Mg2+ binding site [ion binding]; other site
85569012964	G-X-G motif; other site
85569012965	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
85569012966	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
85569012967	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
85569012968	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
85569012969	Domain of unknown function (DUF1996); Region: DUF1996; pfam09362
85569012970	SdiA-regulated; Region: SdiA-regulated; cd09971
85569012971	putative active site [active]
85569012972	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
85569012973	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
85569012974	DNA binding residues [nucleotide binding]
85569012975	dimerization interface [polypeptide binding]; other site
85569012976	AraC family transcriptional regulator; Provisional; Region: PRK15186
85569012977	Protein of unknown function (DUF4238); Region: DUF4238; pfam14022
85569012978	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569012979	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569012980	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
85569012981	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569012982	Coenzyme A binding pocket [chemical binding]; other site
85569012983	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
85569012984	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
85569012985	active site
85569012986	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
85569012987	Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily; Region: HTH_MerR-like_sg3; cd01282
85569012988	DNA binding residues [nucleotide binding]
85569012989	putative dimer interface [polypeptide binding]; other site
85569012990	putative transcriptional regulator; Provisional; Region: PRK11640
85569012991	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
85569012992	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
85569012993	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
85569012994	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
85569012995	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
85569012996	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
85569012997	DsbD alpha interface [polypeptide binding]; other site
85569012998	catalytic residues [active]
85569012999	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
85569013000	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
85569013001	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
85569013002	Aspartase; Region: Aspartase; cd01357
85569013003	active sites [active]
85569013004	tetramer interface [polypeptide binding]; other site
85569013005	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
85569013006	putative transporter; Provisional; Region: PRK11021
85569013007	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
85569013008	oligomerisation interface [polypeptide binding]; other site
85569013009	mobile loop; other site
85569013010	roof hairpin; other site
85569013011	chaperonin GroEL; Reviewed; Region: groEL; PRK12850
85569013012	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
85569013013	ring oligomerisation interface [polypeptide binding]; other site
85569013014	ATP/Mg binding site [chemical binding]; other site
85569013015	stacking interactions; other site
85569013016	hinge regions; other site
85569013017	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
85569013018	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
85569013019	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569013020	FeS/SAM binding site; other site
85569013021	elongation factor P; Validated; Region: PRK00529
85569013022	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
85569013023	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
85569013024	RNA binding site [nucleotide binding]; other site
85569013025	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
85569013026	RNA binding site [nucleotide binding]; other site
85569013027	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
85569013028	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
85569013029	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569013030	DNA binding residues [nucleotide binding]
85569013031	dimerization interface [polypeptide binding]; other site
85569013032	multidrug efflux system protein; Provisional; Region: PRK11431
85569013033	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
85569013034	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
85569013035	Iron-sulfur protein interface; other site
85569013036	proximal quinone binding site [chemical binding]; other site
85569013037	C-subunit interface; other site
85569013038	distal quinone binding site; other site
85569013039	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
85569013040	D-subunit interface [polypeptide binding]; other site
85569013041	Iron-sulfur protein interface; other site
85569013042	proximal quinone binding site [chemical binding]; other site
85569013043	distal quinone binding site [chemical binding]; other site
85569013044	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
85569013045	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
85569013046	catalytic loop [active]
85569013047	iron binding site [ion binding]; other site
85569013048	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
85569013049	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
85569013050	L-aspartate oxidase; Provisional; Region: PRK06175
85569013051	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
85569013052	poxB regulator PoxA; Provisional; Region: PRK09350
85569013053	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
85569013054	motif 1; other site
85569013055	dimer interface [polypeptide binding]; other site
85569013056	active site
85569013057	motif 2; other site
85569013058	motif 3; other site
85569013059	inner membrane transporter YjeM; Provisional; Region: PRK15238
85569013060	Protein of unknown function (DUF2645); Region: DUF2645; pfam10840
85569013061	putative mechanosensitive channel protein; Provisional; Region: PRK10929
85569013062	Mu-like prophage I protein; Region: Mu-like_Pro; cl19864
85569013063	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
85569013064	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
85569013065	Mechanosensitive ion channel; Region: MS_channel; pfam00924
85569013066	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
85569013067	GTPase RsgA; Reviewed; Region: PRK12288
85569013068	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
85569013069	RNA binding site [nucleotide binding]; other site
85569013070	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
85569013071	GTPase/Zn-binding domain interface [polypeptide binding]; other site
85569013072	GTP/Mg2+ binding site [chemical binding]; other site
85569013073	G4 box; other site
85569013074	G5 box; other site
85569013075	G1 box; other site
85569013076	Switch I region; other site
85569013077	G2 box; other site
85569013078	G3 box; other site
85569013079	Switch II region; other site
85569013080	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
85569013081	catalytic site [active]
85569013082	putative active site [active]
85569013083	putative substrate binding site [chemical binding]; other site
85569013084	dimer interface [polypeptide binding]; other site
85569013085	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
85569013086	substrate binding pocket [chemical binding]; other site
85569013087	membrane-bound complex binding site; other site
85569013088	hinge residues; other site
85569013089	epoxyqueuosine reductase; Region: TIGR00276
85569013090	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
85569013091	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
85569013092	putative carbohydrate kinase; Provisional; Region: PRK10565
85569013093	Uncharacterized conserved protein [Function unknown]; Region: COG0062
85569013094	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
85569013095	putative substrate binding site [chemical binding]; other site
85569013096	putative ATP binding site [chemical binding]; other site
85569013097	ADP-binding protein; Provisional; Region: PRK10646
85569013098	GTPase SAR1 and related small G proteins [General function prediction only]; Region: COG1100
85569013099	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
85569013100	AMIN domain; Region: AMIN; pfam11741
85569013101	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
85569013102	active site
85569013103	metal binding site [ion binding]; metal-binding site
85569013104	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
85569013105	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569013106	ATP binding site [chemical binding]; other site
85569013107	Mg2+ binding site [ion binding]; other site
85569013108	G-X-G motif; other site
85569013109	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
85569013110	ATP binding site [chemical binding]; other site
85569013111	MutL C terminal dimerization domain; Region: MutL_C; pfam08676
85569013112	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
85569013113	bacterial Hfq-like; Region: Hfq; cd01716
85569013114	hexamer interface [polypeptide binding]; other site
85569013115	Sm1 motif; other site
85569013116	RNA binding site [nucleotide binding]; other site
85569013117	Sm2 motif; other site
85569013118	GTPase HflX; Provisional; Region: PRK11058
85569013119	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
85569013120	HflX GTPase family; Region: HflX; cd01878
85569013121	G1 box; other site
85569013122	GTP/Mg2+ binding site [chemical binding]; other site
85569013123	Switch I region; other site
85569013124	G2 box; other site
85569013125	G3 box; other site
85569013126	Switch II region; other site
85569013127	G4 box; other site
85569013128	G5 box; other site
85569013129	FtsH protease regulator HflK; Provisional; Region: PRK10930
85569013130	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
85569013131	High frequency of lysogenization K (HflK) family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_HflK; cd03404
85569013132	HflC protein; Region: hflC; TIGR01932
85569013133	High frequency of lysogenization C (HflC) family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_HflC; cd03405
85569013134	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
85569013135	GDP-binding site [chemical binding]; other site
85569013136	ACT binding site; other site
85569013137	IMP binding site; other site
85569013138	transcriptional repressor NsrR; Provisional; Region: PRK11014
85569013139	Rrf2 family protein; Region: rrf2_super; TIGR00738
85569013140	exoribonuclease R; Provisional; Region: PRK11642
85569013141	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
85569013142	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
85569013143	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
85569013144	This domain is the catalytic domain of ribonuclease II; Region: RNB; smart00955
85569013145	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
85569013146	RNA binding site [nucleotide binding]; other site
85569013147	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
85569013148	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
85569013149	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
85569013150	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3789
85569013151	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
85569013152	Ion channel; Region: Ion_trans_2; pfam07885
85569013153	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
85569013154	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
85569013155	Predicted membrane protein [Function unknown]; Region: COG3766
85569013156	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
85569013157	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
85569013158	Predicted integral membrane protein [Function unknown]; Region: COG5463
85569013159	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
85569013160	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
85569013161	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
85569013162	FAD binding site [chemical binding]; other site
85569013163	substrate binding site [chemical binding]; other site
85569013164	catalytic residues [active]
85569013165	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
85569013166	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
85569013167	esterase; Provisional; Region: PRK10566
85569013168	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
85569013169	transcriptional repressor UlaR; Provisional; Region: PRK13509
85569013170	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
85569013171	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
85569013172	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
85569013173	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
85569013174	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
85569013175	active site
85569013176	P-loop; other site
85569013177	phosphorylation site [posttranslational modification]
85569013178	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
85569013179	active site
85569013180	phosphorylation site [posttranslational modification]
85569013181	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
85569013182	active site
85569013183	dimer interface [polypeptide binding]; other site
85569013184	magnesium binding site [ion binding]; other site
85569013185	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
85569013186	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
85569013187	AP (apurinic/apyrimidinic) site pocket; other site
85569013188	DNA interaction; other site
85569013189	Metal-binding active site; metal-binding site
85569013190	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
85569013191	intersubunit interface [polypeptide binding]; other site
85569013192	active site
85569013193	Zn2+ binding site [ion binding]; other site
85569013194	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
85569013195	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
85569013196	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
85569013197	dimer interface [polypeptide binding]; other site
85569013198	ssDNA binding site [nucleotide binding]; other site
85569013199	tetramer (dimer of dimers) interface [polypeptide binding]; other site
85569013200	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
85569013201	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
85569013202	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
85569013203	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
85569013204	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
85569013205	EamA-like transporter family; Region: EamA; pfam00892
85569013206	EamA-like transporter family; Region: EamA; pfam00892
85569013207	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
85569013208	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
85569013209	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
85569013210	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
85569013211	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
85569013212	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
85569013213	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
85569013214	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
85569013215	Hemerythrin-like domain; Region: Hr-like; cd12108
85569013216	Fe binding site [ion binding]; other site
85569013217	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
85569013218	EamA-like transporter family; Region: EamA; pfam00892
85569013219	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
85569013220	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
85569013221	NADP binding site [chemical binding]; other site
85569013222	Predicted transcriptional regulators [Transcription]; Region: COG1733
85569013223	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
85569013224	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
85569013225	active site
85569013226	metal binding site [ion binding]; metal-binding site
85569013227	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
85569013228	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
85569013229	active site
85569013230	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
85569013231	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
85569013232	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
85569013233	Domain of unknown function DUF21; Region: DUF21; pfam01595
85569013234	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
85569013235	Transporter associated domain; Region: CorC_HlyC; smart01091
85569013236	methionine sulfoxide reductase A; Provisional; Region: PRK00058
85569013237	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
85569013238	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
85569013239	Surface antigen; Region: Bac_surface_Ag; pfam01103
85569013240	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
85569013241	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
85569013242	Family of unknown function (DUF490); Region: DUF490; pfam04357
85569013243	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
85569013244	putative active site pocket [active]
85569013245	dimerization interface [polypeptide binding]; other site
85569013246	putative catalytic residue [active]
85569013247	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569013248	D-galactonate transporter; Region: 2A0114; TIGR00893
85569013249	putative substrate translocation pore; other site
85569013250	putative metallo-dependent hydrolase; Provisional; Region: PRK12394
85569013251	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
85569013252	active site
85569013253	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
85569013254	dimer interface [polypeptide binding]; other site
85569013255	substrate binding site [chemical binding]; other site
85569013256	metal binding sites [ion binding]; metal-binding site
85569013257	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
85569013258	AMP binding site [chemical binding]; other site
85569013259	metal binding site [ion binding]; metal-binding site
85569013260	active site
85569013261	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
85569013262	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
85569013263	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
85569013264	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
85569013265	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
85569013266	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
85569013267	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
85569013268	putative active site [active]
85569013269	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
85569013270	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569013271	putative substrate translocation pore; other site
85569013272	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
85569013273	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569013274	putative substrate translocation pore; other site
85569013275	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
85569013276	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
85569013277	tetrameric interface [polypeptide binding]; other site
85569013278	NAD binding site [chemical binding]; other site
85569013279	catalytic residues [active]
85569013280	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
85569013281	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569013282	Helix-turn-helix domain; Region: HTH_18; pfam12833
85569013283	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569013284	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
85569013285	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
85569013286	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
85569013287	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
85569013288	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
85569013289	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
85569013290	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
85569013291	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
85569013292	major facilitator superfamily transporter; Provisional; Region: PRK05122
85569013293	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569013294	putative substrate translocation pore; other site
85569013295	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
85569013296	substrate binding site [chemical binding]; other site
85569013297	ATP binding site [chemical binding]; other site
85569013298	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892
85569013299	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
85569013300	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
85569013301	PYR/PP interface [polypeptide binding]; other site
85569013302	dimer interface [polypeptide binding]; other site
85569013303	TPP binding site [chemical binding]; other site
85569013304	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
85569013305	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
85569013306	TPP-binding site; other site
85569013307	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
85569013308	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
85569013309	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
85569013310	polyol permease family; Region: 2A0118; TIGR00897
85569013311	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569013312	putative substrate translocation pore; other site
85569013313	Predicted sugar epimerase [Carbohydrate transport and metabolism]; Region: COG4130
85569013314	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
85569013315	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
85569013316	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
85569013317	hypothetical protein; Provisional; Region: PRK05255
85569013318	peptidase PmbA; Provisional; Region: PRK11040
85569013319	cytochrome b562; Provisional; Region: PRK15058
85569013320	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
85569013321	Glycine-rich SFCGS; Region: Gly_rich_SFCGS; pfam14272
85569013322	conserved hypothetical protein EF_0831/AHA_3912; Region: EF_0831; TIGR03578
85569013323	conserved hypothetical protein EF_0832/AHA_3913; Region: EF_0832; TIGR03580
85569013324	Domain of unknown function (DUF4310); Region: DUF4310; pfam14187
85569013325	probable amidohydrolase EF_0837/AHA_3915; Region: EF_0837; TIGR03583
85569013326	Metallo-dependent hydrolases, subgroup B is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_B; cd01307
85569013327	active site
85569013328	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
85569013329	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
85569013330	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
85569013331	HTH domain; Region: HTH_11; pfam08279
85569013332	Mga helix-turn-helix domain; Region: Mga; pfam05043
85569013333	PRD domain; Region: PRD; pfam00874
85569013334	PRD domain; Region: PRD; pfam00874
85569013335	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
85569013336	active site
85569013337	P-loop; other site
85569013338	phosphorylation site [posttranslational modification]
85569013339	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
85569013340	active site
85569013341	phosphorylation site [posttranslational modification]
85569013342	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
85569013343	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
85569013344	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
85569013345	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569013346	FeS/SAM binding site; other site
85569013347	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
85569013348	ATP cone domain; Region: ATP-cone; pfam03477
85569013349	Class III ribonucleotide reductase; Region: RNR_III; cd01675
85569013350	effector binding site; other site
85569013351	active site
85569013352	Zn binding site [ion binding]; other site
85569013353	glycine loop; other site
85569013354	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
85569013355	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
85569013356	Ca binding site [ion binding]; other site
85569013357	active site
85569013358	catalytic site [active]
85569013359	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
85569013360	trehalose repressor; Provisional; Region: treR; PRK09492
85569013361	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
85569013362	DNA binding site [nucleotide binding]
85569013363	domain linker motif; other site
85569013364	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
85569013365	dimerization interface [polypeptide binding]; other site
85569013366	ligand binding site [chemical binding]; other site
85569013367	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
85569013368	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
85569013369	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
85569013370	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
85569013371	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569013372	motif II; other site
85569013373	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
85569013374	Transposase; Region: HTH_Tnp_1; cl17663
85569013375	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
85569013376	homotrimer interaction site [polypeptide binding]; other site
85569013377	putative active site [active]
85569013378	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
85569013379	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
85569013380	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
85569013381	aspartate carbamoyltransferase; Region: asp_carb_tr; TIGR00670
85569013382	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
85569013383	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
85569013384	pyrBI operon leader peptide; Provisional; Region: PRK10224
85569013385	Arginine repressor [Transcription]; Region: ArgR; COG1438
85569013386	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
85569013387	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
85569013388	Predicted membrane protein [Function unknown]; Region: COG1288
85569013389	ornithine carbamoyltransferase; Validated; Region: PRK02102
85569013390	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
85569013391	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
85569013392	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
85569013393	putative substrate binding site [chemical binding]; other site
85569013394	nucleotide binding site [chemical binding]; other site
85569013395	nucleotide binding site [chemical binding]; other site
85569013396	homodimer interface [polypeptide binding]; other site
85569013397	arginine deiminase; Provisional; Region: PRK01388
85569013398	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
85569013399	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
85569013400	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
85569013401	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
85569013402	RNase E inhibitor protein; Provisional; Region: PRK11191
85569013403	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
85569013404	active site
85569013405	dinuclear metal binding site [ion binding]; other site
85569013406	dimerization interface [polypeptide binding]; other site
85569013407	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
85569013408	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569013409	Coenzyme A binding pocket [chemical binding]; other site
85569013410	Predicted membrane protein [Function unknown]; Region: COG4269
85569013411	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
85569013412	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
85569013413	active site
85569013414	HIGH motif; other site
85569013415	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
85569013416	KMSKS motif; other site
85569013417	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
85569013418	tRNA binding surface [nucleotide binding]; other site
85569013419	anticodon binding site; other site
85569013420	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
85569013421	DNA polymerase III subunit chi; Validated; Region: PRK05728
85569013422	multifunctional aminopeptidase A; Provisional; Region: PRK00913
85569013423	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
85569013424	interface (dimer of trimers) [polypeptide binding]; other site
85569013425	Substrate-binding/catalytic site; other site
85569013426	Zn-binding sites [ion binding]; other site
85569013427	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
85569013428	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
85569013429	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
85569013430	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
85569013431	DNA binding site [nucleotide binding]
85569013432	domain linker motif; other site
85569013433	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
85569013434	putative dimerization interface [polypeptide binding]; other site
85569013435	putative ligand binding site [chemical binding]; other site
85569013436	gluconate transporter; Region: gntP; TIGR00791
85569013437	GntP family permease; Region: GntP_permease; pfam02447
85569013438	gluconate 5-dehydrogenase; Provisional; Region: PRK07097
85569013439	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
85569013440	NADP binding site [chemical binding]; other site
85569013441	homodimer interface [polypeptide binding]; other site
85569013442	active site
85569013443	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
85569013444	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
85569013445	putative NAD(P) binding site [chemical binding]; other site
85569013446	catalytic Zn binding site [ion binding]; other site
85569013447	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
85569013448	AAA domain; Region: AAA_33; pfam13671
85569013449	ATP-binding site [chemical binding]; other site
85569013450	Gluconate-6-phosphate binding site [chemical binding]; other site
85569013451	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
85569013452	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
85569013453	putative NAD(P) binding site [chemical binding]; other site
85569013454	putative substrate binding site [chemical binding]; other site
85569013455	catalytic Zn binding site [ion binding]; other site
85569013456	structural Zn binding site [ion binding]; other site
85569013457	dimer interface [polypeptide binding]; other site
85569013458	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
85569013459	replicative DNA helicase; Provisional; Region: PRK05973
85569013460	Part of AAA domain; Region: AAA_19; pfam13245
85569013461	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
85569013462	AAA domain; Region: AAA_12; pfam13087
85569013463	C-terminal domain of Escherichia coli uncharacterized protein yjhR and similar proteins; Region: PLDc_yjhR_C_like; cd09118
85569013464	putative active site [active]
85569013465	catalytic site [active]
85569013466	Uncharacterized conserved protein [Function unknown]; Region: COG4127
85569013467	conserved hypothetical protein; Region: Lon_rel_chp; TIGR02653
85569013468	Putative ATP-dependent Lon protease; Region: Lon_2; pfam13337
85569013469	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
85569013470	TIGR02687 family protein; Region: TIGR02687
85569013471	PglZ domain; Region: PglZ; pfam08665
85569013472	Protein of unknown function (DUF4435); Region: DUF4435; pfam14491
85569013473	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
85569013474	Predicted ATPases [General function prediction only]; Region: COG1106
85569013475	Walker A/P-loop; other site
85569013476	ATP binding site [chemical binding]; other site
85569013477	AAA domain; Region: AAA_21; pfam13304
85569013478	ABC transporter signature motif; other site
85569013479	Walker B; other site
85569013480	D-loop; other site
85569013481	H-loop/switch region; other site
85569013482	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
85569013483	Methyltransferase domain; Region: Methyltransf_26; pfam13659
85569013484	TIGR02680 family protein; Region: TIGR02680
85569013485	Domain of unknown function (DUF1788); Region: DUF1788; pfam08747
85569013486	Putative inner membrane protein (DUF1819); Region: DUF1819; pfam08849
85569013487	hypothetical protein; Provisional; Region: PRK12378
85569013488	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569013489	S-adenosylmethionine binding site [chemical binding]; other site
85569013490	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
85569013491	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569013492	S-adenosylmethionine binding site [chemical binding]; other site
85569013493	hypothetical protein; Provisional; Region: PRK13687
85569013494	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4332
85569013495	Uncharacterized conserved protein [Function unknown]; Region: COG3439
85569013496	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
85569013497	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
85569013498	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
85569013499	DNA-binding site [nucleotide binding]; DNA binding site
85569013500	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
85569013501	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
85569013502	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
85569013503	active site
85569013504	HIGH motif; other site
85569013505	dimer interface [polypeptide binding]; other site
85569013506	KMSKS motif; other site
85569013507	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
85569013508	Aspartate racemase [Cell envelope biogenesis, outer membrane]; Region: RacX; COG1794
85569013509	cell density-dependent motility repressor; Provisional; Region: PRK10082
85569013510	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569013511	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
85569013512	dimerization interface [polypeptide binding]; other site
85569013513	isoaspartyl dipeptidase; Provisional; Region: PRK10657
85569013514	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
85569013515	active site
85569013516	hypothetical protein; Provisional; Region: PRK10519
85569013517	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
85569013518	Nucleoside recognition; Region: Gate; pfam07670
85569013519	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569013520	Major Facilitator Superfamily; Region: MFS_1; pfam07690
85569013521	putative substrate translocation pore; other site
85569013522	Predicted membrane protein [Function unknown]; Region: COG2733
85569013523	Protein of unknown function (DUF445); Region: DUF445; pfam04286
85569013524	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
85569013525	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
85569013526	putative substrate translocation pore; other site
85569013527	hypothetical protein; Provisional; Region: PRK09956
85569013528	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
85569013529	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
85569013530	NAD(P) binding site [chemical binding]; other site
85569013531	catalytic residues [active]
85569013532	endoribonuclease SymE; Provisional; Region: PRK13605
85569013533	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
85569013534	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
85569013535	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
85569013536	HsdM N-terminal domain; Region: HsdM_N; pfam12161
85569013537	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
85569013538	Methyltransferase domain; Region: Methyltransf_26; pfam13659
85569013539	type I restriction enzyme EcoKI subunit R; Provisional; Region: hsdR; PRK11448
85569013540	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
85569013541	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
85569013542	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
85569013543	ATP binding site [chemical binding]; other site
85569013544	putative Mg++ binding site [ion binding]; other site
85569013545	Helicase conserved C-terminal domain; Region: Helicase_C; pfam00271
85569013546	EcoEI R protein C-terminal; Region: EcoEI_R_C; pfam08463
85569013547	Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715
85569013548	Mrr N-terminal domain; Region: Mrr_N; pfam14338
85569013549	Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like...; Region: CH; cl00030
85569013550	Restriction endonuclease; Region: Mrr_cat; pfam04471
85569013551	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2929
85569013552	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3514
85569013553	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
85569013554	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
85569013555	P-loop, Walker A motif; other site
85569013556	Base recognition motif; other site
85569013557	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
85569013558	Uncharacterized small protein [Function unknown]; Region: COG2879
85569013559	carbon starvation protein A; Provisional; Region: PRK15015
85569013560	Carbon starvation protein CstA; Region: CstA; pfam02554
85569013561	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
85569013562	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
85569013563	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
85569013564	dimer interface [polypeptide binding]; other site
85569013565	ligand binding site [chemical binding]; other site
85569013566	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569013567	dimerization interface [polypeptide binding]; other site
85569013568	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
85569013569	dimer interface [polypeptide binding]; other site
85569013570	putative CheW interface [polypeptide binding]; other site
85569013571	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
85569013572	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569013573	Walker A motif; other site
85569013574	ATP binding site [chemical binding]; other site
85569013575	Walker B motif; other site
85569013576	arginine finger; other site
85569013577	Transcriptional antiterminator [Transcription]; Region: COG3933
85569013578	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
85569013579	active pocket/dimerization site; other site
85569013580	active site
85569013581	phosphorylation site [posttranslational modification]
85569013582	PRD domain; Region: PRD; pfam00874
85569013583	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
85569013584	active pocket/dimerization site; other site
85569013585	active site
85569013586	phosphorylation site [posttranslational modification]
85569013587	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
85569013588	active site
85569013589	phosphorylation site [posttranslational modification]
85569013590	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
85569013591	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
85569013592	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
85569013593	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
85569013594	dimer interface [polypeptide binding]; other site
85569013595	active site
85569013596	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
85569013597	dimer interface [polypeptide binding]; other site
85569013598	active site
85569013599	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
85569013600	A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS_1; cd05710
85569013601	putative active site [active]
85569013602	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
85569013603	phosphoglycerol transferase I; Provisional; Region: PRK03776
85569013604	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
85569013605	hypothetical protein; Provisional; Region: PRK11667
85569013606	DNA replication protein DnaC; Validated; Region: PRK07952
85569013607	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569013608	Walker A motif; other site
85569013609	ATP binding site [chemical binding]; other site
85569013610	Walker B motif; other site
85569013611	primosomal protein DnaI; Provisional; Region: PRK02854
85569013612	hypothetical protein; Provisional; Region: PRK09917
85569013613	Uncharacterized conserved protein [Function unknown]; Region: COG2966
85569013614	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
85569013615	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
85569013616	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569013617	DNA binding residues [nucleotide binding]
85569013618	dimerization interface [polypeptide binding]; other site
85569013619	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
85569013620	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569013621	DNA binding residues [nucleotide binding]
85569013622	dimerization interface [polypeptide binding]; other site
85569013623	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
85569013624	putative deacylase active site [active]
85569013625	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
85569013626	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
85569013627	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
85569013628	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
85569013629	metal binding site [ion binding]; metal-binding site
85569013630	active site
85569013631	I-site; other site
85569013632	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
85569013633	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
85569013634	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
85569013635	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
85569013636	S-adenosylmethionine binding site [chemical binding]; other site
85569013637	DNA polymerase III subunit psi; Validated; Region: PRK06856
85569013638	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
85569013639	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
85569013640	Coenzyme A binding pocket [chemical binding]; other site
85569013641	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
85569013642	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569013643	motif II; other site
85569013644	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
85569013645	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
85569013646	G1 box; other site
85569013647	putative GEF interaction site [polypeptide binding]; other site
85569013648	GTP/Mg2+ binding site [chemical binding]; other site
85569013649	Switch I region; other site
85569013650	G2 box; other site
85569013651	G3 box; other site
85569013652	Switch II region; other site
85569013653	G4 box; other site
85569013654	G5 box; other site
85569013655	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
85569013656	Elongation Factor G, domain II; Region: EFG_II; pfam14492
85569013657	periplasmic protein; Provisional; Region: PRK10568
85569013658	BON domain; Region: BON; pfam04972
85569013659	BON domain; Region: BON; pfam04972
85569013660	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
85569013661	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
85569013662	active site
85569013663	nucleophile elbow; other site
85569013664	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
85569013665	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
85569013666	FeS/SAM binding site; other site
85569013667	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
85569013668	hypothetical protein; Provisional; Region: PRK10977
85569013669	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
85569013670	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
85569013671	intersubunit interface [polypeptide binding]; other site
85569013672	active site
85569013673	catalytic residue [active]
85569013674	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
85569013675	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
85569013676	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
85569013677	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
85569013678	phosphopentomutase; Provisional; Region: PRK05362
85569013679	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
85569013680	hypothetical protein; Provisional; Region: PRK15301
85569013681	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
85569013682	PapC C-terminal domain; Region: PapC_C; pfam13953
85569013683	PapC N-terminal domain; Region: PapC_N; pfam13954
85569013684	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
85569013685	putative fimbrial chaperone protein; Provisional; Region: PRK09918
85569013686	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
85569013687	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
85569013688	hypothetical protein; Provisional; Region: PRK15302
85569013689	hypothetical protein; Provisional; Region: PRK15303
85569013690	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
85569013691	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
85569013692	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
85569013693	hypothetical protein; Provisional; Region: PRK11246
85569013694	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
85569013695	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
85569013696	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
85569013697	motif II; other site
85569013698	DNA repair protein RadA; Region: sms; TIGR00416
85569013699	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
85569013700	Walker A motif/ATP binding site; other site
85569013701	ATP binding site [chemical binding]; other site
85569013702	Walker B motif; other site
85569013703	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
85569013704	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
85569013705	non-specific DNA binding site [nucleotide binding]; other site
85569013706	salt bridge; other site
85569013707	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
85569013708	sequence-specific DNA binding site [nucleotide binding]; other site
85569013709	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
85569013710	active site
85569013711	(T/H)XGH motif; other site
85569013712	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
85569013713	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
85569013714	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
85569013715	The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013
85569013716	ABC transporter; Region: ABC_tran_2; pfam12848
85569013717	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
85569013718	lytic murein transglycosylase; Provisional; Region: PRK11619
85569013719	Soluble lytic murein transglycosylase L domain; Region: SLT_L; pfam14718
85569013720	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
85569013721	N-acetyl-D-glucosamine binding site [chemical binding]; other site
85569013722	catalytic residue [active]
85569013723	Trp operon repressor; Provisional; Region: PRK01381
85569013724	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
85569013725	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
85569013726	catalytic core [active]
85569013727	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
85569013728	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569013729	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569013730	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
85569013731	hypothetical protein; Provisional; Region: PRK10756
85569013732	DNA-binding response regulator CreB; Provisional; Region: PRK11083
85569013733	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569013734	active site
85569013735	phosphorylation site [posttranslational modification]
85569013736	intermolecular recognition site; other site
85569013737	dimerization interface [polypeptide binding]; other site
85569013738	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
85569013739	DNA binding site [nucleotide binding]
85569013740	sensory histidine kinase CreC; Provisional; Region: PRK11100
85569013741	Sensory domain of two-component sensor kinase; Region: Cache_3; pfam14827
85569013742	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
85569013743	dimerization interface [polypeptide binding]; other site
85569013744	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
85569013745	dimer interface [polypeptide binding]; other site
85569013746	phosphorylation site [posttranslational modification]
85569013747	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
85569013748	ATP binding site [chemical binding]; other site
85569013749	Mg2+ binding site [ion binding]; other site
85569013750	G-X-G motif; other site
85569013751	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
85569013752	putative major fimbrial protein SthE; Provisional; Region: PRK15292
85569013753	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
85569013754	putative fimbrial protein SthD; Provisional; Region: PRK15293
85569013755	putative fimbrial outer membrane usher protein SthC; Provisional; Region: PRK15294
85569013756	PapC N-terminal domain; Region: PapC_N; pfam13954
85569013757	Outer membrane usher protein; Region: Usher; pfam00577
85569013758	PapC C-terminal domain; Region: PapC_C; pfam13953
85569013759	fimbrial assembly chaperone SthB; Provisional; Region: PRK15295
85569013760	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
85569013761	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
85569013762	putative fimbrial protein SthA; Provisional; Region: PRK15296
85569013763	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
85569013764	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
85569013765	two-component response regulator; Provisional; Region: PRK11173
85569013766	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
85569013767	active site
85569013768	phosphorylation site [posttranslational modification]
85569013769	intermolecular recognition site; other site
85569013770	dimerization interface [polypeptide binding]; other site
85569013771	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
85569013772	DNA binding site [nucleotide binding]
85569013773	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
85569013774	putative RNA methyltransferase; Provisional; Region: PRK10433
85569013775	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
85569013776	replication protein; Provisional; Region: PRK13702
85569013777	RepA leader peptide Tap; Provisional; Region: PRK14745
85569013778	replication protein; Provisional; Region: PRK13750
85569013779	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
85569013780	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
85569013781	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
85569013782	resistance to complement killing; Provisional; Region: PRK15240
85569013783	SdiA-regulated; Region: SdiA-regulated; cd09971
85569013784	putative active site [active]
85569013785	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
85569013786	catalytic residues [active]
85569013787	hinge region; other site
85569013788	alpha helical domain; other site
85569013789	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
85569013790	DNA binding residues [nucleotide binding]
85569013791	dimerization interface [polypeptide binding]; other site
85569013792	FaeA-like protein; Region: FaeA; pfam04703
85569013793	fimbrial chaperone protein PefD; Provisional; Region: PRK15211
85569013794	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
85569013795	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
85569013796	fimbrial outer membrane usher protein PefC; Provisional; Region: PRK15213
85569013797	PapC N-terminal domain; Region: PapC_N; pfam13954
85569013798	Outer membrane usher protein; Region: Usher; pfam00577
85569013799	fimbrial protein PefA; Provisional; Region: PRK15214
85569013800	Adhesin biosynthesis transcription regulatory protein; Region: PapB; pfam03333
85569013801	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
85569013802	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
85569013803	plasmid maintenance protein CcdA; Provisional; Region: PRK13710
85569013804	plasmid maintenance protein CcdB; Provisional; Region: PRK13708
85569013805	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
85569013806	active site
85569013807	catalytic residues [active]
85569013808	DNA binding site [nucleotide binding]
85569013809	Int/Topo IB signature motif; other site
85569013810	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
85569013811	Protein of unknown function (DUF1401); Region: DUF1401; pfam07180
85569013812	bacteriophage N4 receptor, outer membrane subunit; Provisional; Region: PRK09782
85569013813	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
85569013814	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
85569013815	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
85569013816	Transposase IS200 like; Region: Y1_Tnp; pfam01797
85569013817	virulence protein SpvD; Provisional; Region: PRK15250
85569013818	type III effector phosphothreonine lyase; Provisional; Region: PRK15245
85569013819	virulence protein SpvB; Provisional; Region: PRK15244
85569013820	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
85569013821	VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cl00173
85569013822	active site
85569013823	conformational flexibility of ligand binding pocket; other site
85569013824	ADP-ribosylating toxin turn-turn motif; other site
85569013825	virulence protein SpvA; Provisional; Region: PRK15212
85569013826	transcriptional regulator SpvR; Provisional; Region: PRK15243
85569013827	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
85569013828	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
85569013829	Homeodomain-like domain; Region: HTH_23; pfam13384
85569013830	Winged helix-turn helix; Region: HTH_29; pfam13551
85569013831	Homeodomain-like domain; Region: HTH_32; pfam13565
85569013832	DDE superfamily endonuclease; Region: DDE_3; pfam13358
85569013833	Type II secretory pathway, component ExeA (predicted ATPase) [Intracellular trafficking and secretion]; Region: ExeA; COG3267
85569013834	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
85569013835	Walker A motif; other site
85569013836	ATP binding site [chemical binding]; other site
85569013837	Walker B motif; other site
85569013838	Integrase core domain; Region: rve; pfam00665
85569013839	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
85569013840	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
85569013841	catalytic residues [active]
85569013842	catalytic nucleophile [active]
85569013843	Presynaptic Site I dimer interface [polypeptide binding]; other site
85569013844	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
85569013845	Synaptic Flat tetramer interface [polypeptide binding]; other site
85569013846	Synaptic Site I dimer interface [polypeptide binding]; other site
85569013847	DNA binding site [nucleotide binding]
85569013848	Helix-turn-helix domain of Hin and related proteins; Region: HTH_Hin_like; cl17393
85569013849	DNA-binding interface [nucleotide binding]; DNA binding site
85569013850	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
85569013851	active site clefts [active]
85569013852	zinc binding site [ion binding]; other site
85569013853	dimer interface [polypeptide binding]; other site
85569013854	Plasmid replication region DNA-binding N-term; Region: KfrA_N; pfam11740
85569013855	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
85569013856	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
85569013857	catalytic site [active]
85569013858	Protein of unknown function (DUF2913); Region: DUF2913; pfam11140
85569013859	Uncharacterized conserved protein [Function unknown]; Region: COG5464
85569013860	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
85569013861	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
85569013862	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
85569013863	P-loop; other site
85569013864	Magnesium ion binding site [ion binding]; other site
85569013865	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
85569013866	ParB-like nuclease domain; Region: ParBc; pfam02195
85569013867	ParB family; Region: ParB; pfam08775
85569013868	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
85569013869	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
85569013870	active site
85569013871	DNA binding site [nucleotide binding]
85569013872	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
85569013873	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
85569013874	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
85569013875	Catalytic site [active]
85569013876	putative methylase; Provisional; Region: PRK13699
85569013877	Antirestriction protein; Region: Antirestrict; pfam03230
85569013878	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
85569013879	DNA polymerase III, theta subunit; Region: DNA_pol3_theta; pfam06440
85569013880	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
85569013881	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
85569013882	dimer interface [polypeptide binding]; other site
85569013883	ssDNA binding site [nucleotide binding]; other site
85569013884	tetramer (dimer of dimers) interface [polypeptide binding]; other site
85569013885	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
85569013886	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
85569013887	ParB-like nuclease domain; Region: ParBc; pfam02195
85569013888	Bacteriophage replication protein O; Region: Phage_rep_O; cl04545
85569013889	Plasmid SOS inhibition protein (PsiB); Region: PsiB; pfam06290
85569013890	PsiA protein; Region: PsiA; pfam06952
85569013891	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
85569013892	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
85569013893	N-acetyl-D-glucosamine binding site [chemical binding]; other site
85569013894	catalytic residue [active]
85569013895	conjugal transfer protein TraM; Provisional; Region: PRK13713
85569013896	conjugal transfer transcriptional regulator TraJ; Provisional; Region: PRK13719
85569013897	PAS domain; Region: PAS_8; pfam13188
85569013898	conjugal transfer pilin subunit TraA; Provisional; Region: PRK13734
85569013899	conjugal transfer pilus assembly protein TraL; Provisional; Region: PRK13707
85569013900	conjugal transfer pilus assembly protein TraE; Provisional; Region: PRK13726
85569013901	conjugal transfer protein TraK; Provisional; Region: PRK13736
85569013902	conjugal transfer pilus assembly protein TraB; Provisional; Region: PRK13729
85569013903	Aflatoxin regulatory protein; Region: AflR; pfam08493
85569013904	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
85569013905	TraP protein; Region: TraP; pfam07296
85569013906	conjugal transfer protein TrbD; Provisional; Region: PRK13724
85569013907	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
85569013908	conjugal transfer protein TraV; Provisional; Region: PRK13733
85569013909	conjugal transfer protein TraR; Provisional; Region: PRK13715
85569013910	conjugal transfer ATP-binding protein TraC; Provisional; Region: PRK13721
85569013911	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
85569013912	Domain of unknown function DUF87; Region: DUF87; cl19135
85569013913	conjugal transfer protein TrbI; Provisional; Region: PRK13717
85569013914	conjugal transfer pilus assembly protein TraW; Provisional; Region: PRK13738
85569013915	conjugal transfer pilus assembly protein TraU; Provisional; Region: PRK13737
85569013916	conjugal transfer pilus assembly protein TrbC; Provisional; Region: PRK13730
85569013917	conjugal transfer mating pair stabilization protein TraN; Reviewed; Region: PRK12355
85569013918	type-F conjugative transfer system mating-pair stabilization protein TraN; Region: TraN_Ftype; TIGR02750
85569013919	conjugal transfer protein TrbE; Provisional; Region: PRK13718
85569013920	conjugal pilus assembly protein TraF; Provisional; Region: PRK13703
85569013921	conjugal transfer pilin chaperone TraQ; Provisional; Region: PRK13727
85569013922	conjugal transfer protein TrbB; Provisional; Region: PRK13728
85569013923	conjugal transfer pilus assembly protein TraH; Provisional; Region: PRK13723
85569013924	conjugal transfer mating pair stabilization protein TraG; Provisional; Region: PRK13735
85569013925	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
85569013926	Plasmid conjugative transfer entry exclusion protein TraS; Region: TraS; pfam10624
85569013927	conjugal transfer surface exclusion protein TraT; Provisional; Region: PRK13731
85569013928	type IV conjugative transfer system coupling protein TraD; Region: TraD_Ftype; TIGR02759
85569013929	F sex factor protein N terminal; Region: TraD_N; pfam12615
85569013930	Bacterial conjugation protein TrwB,  ATP binding domain. TrwB is a homohexamer encoded by conjugative plasmids in Gram-negative bacteria. TrwB also has an all alpha domain which has been hypothesized to be responsible for DNA binding. TrwB is a component...; Region: TrwB; cd01127
85569013931	multimer interface [polypeptide binding]; other site
85569013932	Walker A motif; other site
85569013933	ATP binding site [chemical binding]; other site
85569013934	Walker B motif; other site
85569013935	conjugal transfer nickase/helicase TraI; Provisional; Region: PRK13709
85569013936	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
85569013937	AAA domain; Region: AAA_30; pfam13604
85569013938	DNA helicase TraI; Region: TraI; pfam07057
85569013939	conjugal transfer pilus acetylation protein TraX; Provisional; Region: PRK13706
85569013940	conjugal transfer fertility inhibition protein FinO; Provisional; Region: PRK13754
85569013941	Fertility inhibition protein N terminal; Region: FinO_N; pfam12602
85569013942	FinO bacterial conjugation repressor domain;  the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which...; Region: FinO_conjug_rep; cl15270
85569013943	putative kissing complex interaction region; other site
85569013944	putative RNA binding sites [nucleotide binding]; other site