-- dump date 20140620_064703 -- class Genbank::CDS -- table cds_note -- id note YP_961408.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_961409.1 KEGG: shm:Shewmr7_0002 DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain YP_961410.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_961411.1 KEGG: son:SO0011 DNA gyrase subunit B; TIGRFAM: DNA gyrase, B subunit; PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein domain protein; TOPRIM domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein; SMART: DNA topoisomerase II YP_961412.1 PFAM: HDOD; KEGG: shm:Shewmr7_0007 putative signal transduction protein YP_961413.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_961414.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_961415.1 KEGG: shm:Shewmr7_0010 DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase YP_961416.1 PFAM: peptidase S9B, dipeptidylpeptidase IV domain protein; amidohydrolase; WD40 domain protein beta Propeller; KEGG: she:Shewmr4_0011 amidohydrolase YP_961417.1 KEGG: she:Shewmr4_0012 hypothetical protein YP_961418.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_961419.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_961420.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_961421.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_961422.1 PFAM: protein of unknown function UPF0029; KEGG: shm:Shewmr7_0018 protein of unknown function UPF0029 YP_961423.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: she:Shewmr4_0021 potassium uptake protein, TrkH family YP_961424.1 KEGG: shm:Shewmr7_0020 protoporphyrinogen oxidase YP_961425.1 PFAM: regulatory protein, ArsR; KEGG: shm:Shewmr7_0021 transcriptional regulator, ArsR family YP_961426.1 KEGG: she:Shewmr4_0024 protoporphyrinogen oxidase YP_961427.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: she:Shewmr4_0025 potassium uptake protein, TrkH family YP_961428.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_961429.1 TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: she:Shewmr4_0027 sun protein YP_961430.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: shm:Shewmr7_0026 methionyl-tRNA formyltransferase YP_961431.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_961432.1 PFAM: Peptidoglycan-binding LysM; KEGG: shm:Shewmr7_0028 peptidoglycan-binding LysM YP_961433.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: she:Shewmr4_0031 DNA protecting protein DprA YP_961434.1 PFAM: protein of unknown function DUF494; KEGG: son:SO0035 Smg protein YP_961435.1 PFAM: DNA topoisomerase, type IA, zn finger domain protein; KEGG: shm:Shewmr7_0031 DNA topoisomerase, type IA, zn finger domain protein YP_961436.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: son:SO0037 Sua5/YciO/YrdC/YwlC family protein YP_961437.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_961438.1 PFAM: globin; KEGG: son:SO0039 hypothetical globin YP_961439.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_961440.1 PFAM: protein of unknown function DUF1488; KEGG: shm:Shewmr7_0036 protein of unknown function DUF1488 YP_961441.1 KEGG: shm:Shewmr7_0037 carbonic anhydrase, family 3 YP_961442.1 KEGG: shm:Shewmr7_4007 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_961443.1 PFAM: alpha/beta hydrolase fold; KEGG: she:Shewmr4_3914 alpha/beta hydrolase fold YP_961444.1 PFAM: protein of unknown function DUF885; KEGG: shm:Shewmr7_4005 protein of unknown function DUF885 YP_961445.1 catalyzes the formation of inosine from adenosine YP_961446.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_961447.1 KEGG: shm:Shewmr7_4002 hypothetical protein YP_961448.1 PFAM: protein of unknown function DUF414; KEGG: son:SO4728 hypothetical protein YP_961449.1 KEGG: son:SO4727 hypothetical protein YP_961450.1 PFAM: cytochrome c, class I; KEGG: son:SO4666 cytochrome c YP_961451.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_961452.1 KEGG: shm:Shewmr7_3997 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2 YP_961453.1 PFAM: ThiJ/PfpI domain protein; KEGG: son:SO4670 enhancing lycopene biosynthesis protein YP_961454.1 PFAM: Rhomboid family protein; KEGG: shm:Shewmr7_3995 rhomboid family protein YP_961455.1 PFAM: Rhodanese domain protein; KEGG: shm:Shewmr7_3994 rhodanese domain protein YP_961456.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_961457.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_961458.1 PFAM: regulatory protein, TetR; KEGG: son:SO4675 transcriptional regulator, TetR family YP_961459.1 PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain protein; KEGG: she:Shewmr4_3898 three-deoxy-D-manno-octulosonic-acid transferase domain protein YP_961460.1 catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position YP_961461.1 PFAM: glycosyl transferase, family 9; KEGG: son:SO4678 heptosyl transferase, glycosyltransferase family 9 protein YP_961462.1 PFAM: glycosyl transferase, group 1; KEGG: son:SO4679 glycosyl transferase, group 1 family protein YP_961463.1 PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; KEGG: son:SO4680 hypothetical protein YP_961464.1 PFAM: glycosyl transferase, family 2; KEGG: bfs:BF0187 putative glycosyltransferase YP_961465.1 PFAM: glycosyl transferase, group 1; KEGG: she:Shewmr4_3889 glycosyl transferase, group 1 YP_961466.1 PFAM: sulfatase; KEGG: vvy:VV0298 predicted hydrolase YP_961467.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_961468.1 KEGG: shm:Shewmr7_3982 hypothetical protein YP_961469.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: shm:Shewmr7_3979 UDP-glucuronate 5'-epimerase YP_961470.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: son:SO4687 UDP-glucose 6-dehydrogenase YP_961471.1 PFAM: glycosyl transferase, family 2; KEGG: she:Shewmr4_3884 glycosyl transferase, family 2 YP_961472.1 KEGG: shm:Shewmr7_3976 hypothetical protein YP_961473.1 PFAM: glycosyl transferase, family 39; KEGG: shm:Shewmr7_3975 glycosyl transferase, family 39 YP_961474.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_961475.1 KEGG: son:SO4725 hypothetical protein YP_961476.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_961477.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin binding domain; molybdopterin-guanine dinucleotide biosynthesis MobB region; MoeA domain protein, domain I and II; MoeA domain protein, domain IV; KEGG: she:Shewmr4_3878 molybdopterin-guanine dinucleotide biosynthesis protein B YP_961478.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein A; KEGG: son:SO4722 molybdopterin-guanine dinucleotide biosynthesis protein YP_961479.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_3969 ABC transporter related YP_961480.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_3968 binding-protein-dependent transport systems inner membrane component YP_961481.1 PFAM: extracellular solute-binding protein, family 1; KEGG: she:Shewmr4_3874 extracellular solute-binding protein, family 1 YP_961482.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_3966 two component, sigma54 specific, transcriptional regulator, fis family YP_961483.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: shm:Shewmr7_3965 periplasmic sensor signal transduction histidine kinase YP_961484.1 KEGG: she:Shewmr4_3871 acetyltransferase, GNAT family YP_961485.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: son:SO4715 hypothetical protein YP_961486.1 KEGG: she:Shewmr4_3869 hypothetical protein YP_961487.1 TIGRFAM: isochorismate synthases; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: she:Shewmr4_3868 isochorismate synthases YP_961488.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: she:Shewmr4_3866 ABC transporter related YP_961489.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: son:SO4711 HD domain protein YP_961490.1 PFAM: Paraquat-inducible protein A; KEGG: shm:Shewmr7_3953 paraquat-inducible protein A YP_961491.1 KEGG: shm:Shewmr7_3947 hypothetical protein YP_961492.1 PFAM: conserved hypothetical protein 698; KEGG: shm:Shewmr7_3946 conserved hypothetical protein 698 YP_961493.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_961494.1 PFAM: helix-turn-helix domain protein; KEGG: shm:Shewmr7_3944 transcriptional regulator, XRE family YP_961495.1 PFAM: homocysteine S-methyltransferase; KEGG: ppu:PP_0658 homocysteine S-methyltransferase family protein YP_961496.1 PFAM: amino acid permease-associated region; KEGG: pmu:PM0162 arginine/ornithine antiporter, putative YP_961497.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_0950 TonB-dependent siderophore receptor YP_961498.1 converts protoheme IX and farnesyl diphosphate to heme O YP_961499.1 PFAM: cytochrome C oxidase subunit IV; KEGG: shm:Shewmr7_3917 cytochrome c oxidase subunit IV YP_961500.1 PFAM: cytochrome c oxidase, subunit III; KEGG: she:Shewmr4_3825 cytochrome c oxidase, subunit III YP_961501.1 PFAM: cytochrome c oxidase, subunit I; KEGG: shm:Shewmr7_3915 cytochrome-c oxidase YP_961502.1 TIGRFAM: ubiquinol oxidase, subunit II; PFAM: cytochrome c oxidase, subunit II; COX aromatic rich domain protein; KEGG: she:Shewmr4_3823 ubiquinol oxidase, subunit II YP_961503.1 KEGG: she:Shewmr4_3822 hypothetical protein YP_961504.1 KEGG: shm:Shewmr7_3912 diguanylate cyclase/phosphodiesterase with PAS/PAC and CHASE sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; CHASE domain protein; MASE1 domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_961505.1 KEGG: son:SO4656 hypothetical protein YP_961506.1 KEGG: shm:Shewmr7_3910 hypothetical protein YP_961507.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO4648 sensor histidine kinase YP_961508.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO4647 DNA-binding response regulator YP_961509.1 PFAM: Propeptide, PepSY amd peptidase M4; KEGG: shm:Shewmr7_3907 propeptide, PepSY amd peptidase M4 YP_961510.1 KEGG: shm:Shewmr7_3906 hypothetical protein YP_961511.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shm:Shewmr7_3905 redoxin domain protein YP_961512.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_3904 methyl-accepting chemotaxis sensory transducer YP_961513.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_961514.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_961515.1 TIGRFAM: transcription elongation factor GreB; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: she:Shewmr4_3810 transcription elongation factor GreB YP_961516.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase, RNase H domain protein fold; KEGG: son:SO4629 hypothetical protein YP_961517.1 PFAM: sulfatase; KEGG: shm:Shewmr7_3884 sulfatase YP_961518.1 KEGG: she:Shewmr4_3807 hypothetical protein YP_961519.1 TIGRFAM: bioH protein; PFAM: alpha/beta hydrolase fold; KEGG: shm:Shewmr7_3882 BioH protein YP_961520.1 KEGG: son:SO4625 competence protein ComF YP_961521.1 PFAM: regulatory protein, LuxR; KEGG: son:SO4624 transcriptional regulator, LuxR family YP_961522.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO4623 DNA-binding response regulator YP_961523.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4622 sensor histidine kinase YP_961524.1 KEGG: son:SO4621 hypothetical protein YP_961525.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FMN-binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO4620 fumarate reductase, flavoprotein subunit precursor YP_961526.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_961528.1 KEGG: rpe:RPE_0798 hypothetical protein YP_961530.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO4617 DNA-damage-inducible protein F YP_961531.1 PFAM: polysaccharide deacetylase; KEGG: she:Shewmr4_3801 polysaccharide deacetylase YP_961532.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; electron transport protein SCO1/SenC; KEGG: shm:Shewmr7_3873 electron transport protein SCO1/SenC YP_961533.1 converts protoheme IX and farnesyl diphosphate to heme O YP_961534.1 PFAM: cytochrome oxidase assembly; KEGG: son:SO4613 cytochrome oxidase assembly protein, putative YP_961535.1 KEGG: son:SO4612 hypothetical protein YP_961536.1 KEGG: she:Shewmr4_3796 hypothetical protein YP_961537.1 PFAM: cytochrome c oxidase, subunit III; KEGG: shm:Shewmr7_3867 cytochrome c oxidase, subunit III YP_961538.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_961539.1 PFAM: cytochrome c oxidase, subunit I; KEGG: shm:Shewmr7_3865 cytochrome-c oxidase YP_961540.1 PFAM: cytochrome c oxidase, subunit II; cytochrome c, class I; cytochrome C oxidase subunit II, transmembrane region; KEGG: she:Shewmr4_3791 cytochrome c oxidase, subunit II YP_961541.1 KEGG: she:Shewmr4_3790 hypothetical protein YP_961542.1 Represses a number of genes involved in the response to DNA damage YP_961543.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_961544.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter, transmembrane; KEGG: son:SO4601 tryptophan-specific transport protein YP_961545.1 PFAM: ribonuclease T2; KEGG: son:SO4599 ribonuclease, T2 family YP_961546.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_961547.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_961548.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_961549.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_961550.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_961551.1 KEGG: shm:Shewmr7_0182 NusG antitermination factor; TIGRFAM: transcription termination/antitermination factor NusG; PFAM: transcription antitermination protein NusG; KOW domain protein; SMART: NGN domain protein; KOW (Kyrpides, Ouzounis, Woese) domain protein YP_961552.1 binds directly to 23S ribosomal RNA YP_961553.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_961554.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_961555.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_961556.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_961557.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_961558.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_961559.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_961560.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_961561.2 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_961562.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_961563.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_961564.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_961565.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_961566.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_961567.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_961568.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_961569.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_961570.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_961571.1 one of the stabilizing components for the large ribosomal subunit YP_961572.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_961573.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_961574.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_961575.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_961576.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_961577.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_961578.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_961579.1 binds 5S rRNA along with protein L5 and L25 YP_961580.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_961581.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_961582.1 late assembly protein YP_961583.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_961584.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_961585.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_961586.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_961587.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_961588.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_961589.1 is a component of the macrolide binding site in the peptidyl transferase center YP_961590.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_961591.1 PFAM: Heme exporter protein D (CcmD); KEGG: shm:Shewmr7_0223 heme exporter protein D (CcmD) YP_961592.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein; KEGG: son:SO0261 heme exporter protein CcmC YP_961593.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: son:SO0262 heme exporter protein CcmB YP_961594.1 ATP-binding protein; required for proper cytochrome c maturation YP_961595.1 PFAM: cytochrome c, class I; KEGG: shm:Shewmr7_0227 cytochrome c, class I YP_961596.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: son:SO0265 cytochrome c-type biogenesis protein CcmH YP_961597.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: shm:Shewmr7_0229 cytochrome c-type biogenesis protein CcmF YP_961598.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: Redoxin domain protein; KEGG: son:SO0267 thiol:disulfide interchange protein DsbE YP_961599.1 PFAM: cytochrome C biogenesis protein; KEGG: son:SO0268 cytochrome c-type biogenesis protein CcmH YP_961600.1 PFAM: Redoxin domain protein; KEGG: shm:Shewmr7_0232 redoxin domain protein YP_961601.1 KEGG: shm:Shewmr7_3783 hypothetical protein YP_961602.1 KEGG: son:SO4490 hypothetical protein YP_961603.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; KEGG: bsu:BG12951 similar to 2-oxoglutarate/malate translocator YP_961604.1 TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; Fe-S type hydro-lyases tartrate/fumarate beta region; KEGG: ppr:PBPRA2409 putative fumarate hydratase, class I YP_961605.1 PFAM: response regulator receiver; Helix-turn-helix, type 11 domain protein; KEGG: vpa:VP1711 response regulator YP_961606.1 PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: bld:BLi01245 hypothetical protein YP_961607.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_961608.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_961609.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_961610.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_961611.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO4489 acetyltransferase, GNAT family YP_961612.1 PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: son:SO4488 sensor histidine kinase YP_961613.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3781 two component transcriptional regulator, winged helix family YP_961614.1 PFAM: Propeptide, PepSY amd peptidase M4; KEGG: shm:Shewmr7_3780 propeptide, PepSY amd peptidase M4 YP_961615.1 KEGG: son:SO4485 diheme cytochrome c YP_961616.1 KEGG: shm:Shewmr7_3778 cytochrome c-type protein Shp YP_961617.1 PFAM: cytochrome B561; KEGG: son:SO4483 cytochrome b, putative YP_961618.1 KEGG: she:Shewmr4_0245 hypothetical protein YP_961619.1 KEGG: son:SO4481 hypothetical protein YP_961620.1 PFAM: aldehyde dehydrogenase; KEGG: son:SO4480 aldehyde dehydrogenase YP_961621.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3771 GAF modulated sigma54 specific transcriptional regulator, fis family YP_961622.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4478 sensor protein CpxA YP_961623.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO4477 transcriptional regulatory protein CpxR YP_961624.1 PFAM: protein of unknown function, Spy-related; KEGG: she:Shewmr4_0253 protein of unknown function, Spy-related YP_961625.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: shm:Shewmr7_3767 cation diffusion facilitator family transporter YP_961626.1 KEGG: she:Shewmr4_0255 hypothetical protein YP_961627.1 KEGG: shm:Shewmr7_3764 nitrogen metabolism transcriptional regulator, NtrC, fis family; TIGRFAM: nitrogen regulation protein NR(I); PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_961628.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; KEGG: shm:Shewmr7_3763 signal transduction histidine kinase, nitrogen specific, NtrB YP_961629.1 KEGG: shm:Shewmr7_3762 hypothetical protein YP_961630.1 KEGG: sdn:Sden_1385 glutathione S-transferase-like protein YP_961631.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: vvu:VV20508 glutathione S-transferase YP_961632.1 PFAM: ThiJ/PfpI domain protein; KEGG: psb:Psyr_3319 ThiJ/PfpI YP_961633.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: son:SO4469 alcohol dehydrogenase, iron-containing YP_961634.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_3760 transcriptional regulator, TetR family YP_961635.1 PFAM: protein of unknown function DUF1255; KEGG: shm:Shewmr7_3759 protein of unknown function DUF1255 YP_961636.1 PFAM: chemotaxis sensory transducer; KEGG: shm:Shewmr7_3758 methyl-accepting chemotaxis sensory transducer YP_961637.1 PFAM: protein of unknown function DUF323; Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_3757 protein of unknown function DUF323 YP_961638.1 KEGG: son:SO4463 prolyl 4-hydroxylase, alpha subunit domain protein YP_961639.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_961640.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_961641.1 KEGG: she:Shewmr4_0265 hypothetical protein YP_961642.1 PFAM: PfkB domain protein; KEGG: son:SO4458 carbohydrate kinase, PfkB family YP_961643.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO4457 GGDEF domain protein YP_961644.1 PFAM: 3-alpha; MOSC domain containing protein; KEGG: she:Shewmr4_0269 MOSC domain containing protein YP_961645.1 KEGG: shm:Shewmr7_3751 hypothetical protein YP_961646.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_3750 methyl-accepting chemotaxis sensory transducer YP_961647.1 PFAM: FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase; KEGG: shm:Shewmr7_3749 electron-transferring-flavoprotein dehydrogenase YP_961648.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_961649.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_961650.1 TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: son:SO4450 molybdenum cofactor biosynthesis protein D YP_961651.1 PFAM: molybdopterin biosynthesis MoaE; KEGG: she:Shewmr4_0276 molybdopterin biosynthesis MoaE YP_961652.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; KEGG: she:Shewmr4_0277 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_961653.1 TIGRFAM: molybdate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_3743 molybdate ABC transporter, inner membrane subunit YP_961654.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_3742 ABC transporter related YP_961655.1 KEGG: shm:Shewmr7_3741 hypothetical protein YP_961656.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO4428 DNA-binding response regulator YP_961657.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4427 sensor histidine kinase YP_961658.1 TIGRFAM: pseudouridine synthase Rlu family protein, TIGR01621; PFAM: pseudouridine synthase; KEGG: she:Shewmr4_0283 pseudouridine synthase Rlu family protein, TIGR01621 YP_961659.1 PFAM: protein of unknown function UPF0057; KEGG: shm:Shewmr7_3736 protein of unknown function UPF0057 YP_961660.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_0286 TonB-dependent receptor YP_961661.1 KEGG: son:SO4421 hypothetical protein YP_961662.1 PFAM: peptidase M23B; KEGG: shm:Shewmr7_3731 peptidase M23B YP_961663.1 KEGG: son:SO4419 hypothetical protein YP_961664.1 PFAM: CHAP domain containing protein; KEGG: son:SO4418 trypanothione synthetase domain protein YP_961665.1 KEGG: she:Shewmr4_0294 hypothetical protein YP_961666.1 PFAM: aminotransferase, class V; KEGG: shm:Shewmr7_3724 aminotransferase, class V YP_961667.1 KEGG: son:SO4412 hypothetical protein YP_961668.1 KEGG: vch:VCA0021 hypothetical protein YP_961669.1 KEGG: vch:VCA0021 hypothetical protein YP_961670.1 KEGG: vfi:VF1233 hypothetical protein YP_961671.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_961672.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; KEGG: son:SO4408 virulence regulator BipA YP_961673.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO4407 GGDEF family protein YP_961674.1 KEGG: she:Shewmr4_0311 catalase/peroxidase HPI; TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase YP_961675.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_3712 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_961676.1 KEGG: shm:Shewmr7_3709 hypothetical protein YP_961677.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_961678.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_961679.1 TIGRFAM: thioesterase domain, putative; KEGG: son:SO4397 hypothetical acetyltransferase YP_961680.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap; KEGG: mag:amb2240 TPR repeat YP_961682.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_961683.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; KEGG: shm:Shewmr7_3700 transcriptional regulator, XRE family YP_961684.1 TIGRFAM: benzoate transporter; PFAM: Benzoate membrane transport protein; Xanthine/uracil/vitamin C permease; KEGG: shm:Shewmr7_3699 benzoate transporter YP_961685.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_3696 GCN5-related N-acetyltransferase YP_961686.1 SMART: HNH nuclease; KEGG: dar:Daro_1328 hypothetical protein YP_961687.1 PFAM: plasmid stabilization system; KEGG: shm:Shewmr7_3694 plasmid stabilization system YP_961688.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: shm:Shewmr7_3693 prevent-host-death family protein YP_961689.1 KEGG: she:Shewmr4_0334 hypothetical protein YP_961690.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_961691.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_961692.1 KEGG: son:SO4381 thioester dehydrase family protein YP_961693.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_961694.1 KEGG: she:Shewmr4_0339 hypothetical protein YP_961695.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; tryptophan halogenase; KEGG: shm:Shewmr7_3686 monooxygenase, FAD-binding protein YP_961696.1 KEGG: she:Shewmr4_0341 hypothetical protein YP_961697.1 KEGG: she:Shewmr4_0342 hypothetical protein YP_961698.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_3683 thioesterase superfamily protein YP_961699.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: she:Shewmr4_0344 histidine ammonia-lyase YP_961700.1 PFAM: glycosyl transferase, family 2; lipid A biosynthesis acyltransferase; KEGG: she:Shewmr4_0345 glycosyl transferase, family 2 YP_961701.1 KEGG: son:SO4372 thioester dehydrase family protein YP_961702.1 KEGG: shm:Shewmr7_3679 hypothetical protein YP_961703.1 KEGG: shm:Shewmr7_3678 hypothetical protein YP_961704.1 carries the fatty acid chain in fatty acid biosynthesis YP_961705.1 KEGG: son:SO4368 acyl carrier protein, putative YP_961706.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: she:Shewmr4_0351 phospholipid/glycerol acyltransferase YP_961707.1 KEGG: she:Shewmr4_0352 hypothetical protein YP_961708.1 KEGG: son:SO4365 hypothetical protein YP_961709.1 catalyzes branch migration in Holliday junction intermediates YP_961710.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function YP_961711.1 PFAM: OmpA/MotB domain protein; KEGG: she:Shewmr4_0916 OmpA/MotB domain protein YP_961714.1 PFAM: HipA domain protein; KEGG: vvy:VV0798 hypothetical protein YP_961715.1 PFAM: helix-turn-helix domain protein; KEGG: vvu:VV10402 predicted transcriptional regulator YP_961716.1 PFAM: transposase IS3/IS911 family protein; KEGG: bxe:Bxe_A0222 type I site-specific deoxyribonuclease HsdR YP_961717.1 PFAM: protein of unknown function UPF0150; KEGG: plu:plu2506 hypothetical protein YP_961718.1 KEGG: eca:ECA0367 putative DNA-binding protein YP_961719.1 TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; protein of unknown function UPF0174; Miro domain protein; KEGG: ilo:IL0536 predicted C-terminal GTPase domain fused to uncharaterized conserved domain YP_961721.1 PFAM: sigma-54 factor, interaction domain-containing protein; SMART: AAA ATPase; KEGG: ilo:IL0537 possible regulatory protein containing AAA-type ATPase domain YP_961722.1 TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; KEGG: noc:Noc_2903 type I restriction-modification system M subunit YP_961723.1 PFAM: restriction modification system DNA specificity domain; KEGG: mja:MJ0130m type I restriction-modification enzyme, S subunit YP_961726.1 KEGG: son:SO0380 type I restriction-modification system, R subunit; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like YP_961727.1 PFAM: protein of unknown function DUF45; KEGG: son:SO0379 hypothetical protein YP_961728.1 KEGG: bam:Bamb_0004 GTPase subunit of restriction endonuclease-like protein YP_961729.1 KEGG: ppr:PBPRC0061 hypothetical protein YP_961732.1 KEGG: son:SO4260 hypothetical protein YP_961733.1 PFAM: Prophage CP4-57 regulatory; KEGG: cps:CPS_2017 hypothetical protein YP_961735.1 PFAM: phage integrase family protein; KEGG: sdn:Sden_0317 phage integrase YP_961736.1 PFAM: YicC N-terminal domain protein; domain of unknown function DUF1732; KEGG: shm:Shewmr7_0351 hypothetical protein YP_961737.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_961738.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_961739.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_961740.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_961741.1 catalyzes the formation of dUMP from dUTP YP_961742.1 KEGG: shm:Shewmr7_0358 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein YP_961743.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_961744.1 required for 70S ribosome assembly YP_961745.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_961746.1 KEGG: pha:PSHAa2360 phage integrase YP_961747.1 KEGG: vch:VC0184 hypothetical protein YP_961748.1 PFAM: phage integrase family protein; KEGG: vch:VC0183 hypothetical protein YP_961750.1 KEGG: sec:SC146 hypothetical protein YP_961751.1 KEGG: sec:SC145 hypothetical protein YP_961752.1 KEGG: eba:ebB231 hypothetical protein YP_961753.1 PFAM: transcriptional regulator TrmB; Penicillinase repressor; KEGG: sfr:Sfri_2523 transcriptional repressor, CopY family protein YP_961754.1 PFAM: peptidase M56, BlaR1; KEGG: sfr:Sfri_2522 peptidase M56, BlaR1 YP_961755.1 KEGG: tcx:Tcr_2097 outer membrane efflux protein YP_961756.1 KEGG: tcx:Tcr_2096 secretion protein HlyD YP_961757.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: tcx:Tcr_2095 heavy metal efflux pump CzcA YP_961758.1 KEGG: sfr:Sfri_2521 hypothetical protein YP_961759.1 KEGG: sfr:Sfri_2520 hypothetical protein YP_961760.1 KEGG: sfr:Sfri_2519 hypothetical protein YP_961762.1 KEGG: shm:Shewmr7_2217 hypothetical protein YP_961763.1 PFAM: transposase IS3/IS911 family protein; KEGG: vch:VCA0792 transposase OrfAB, subunit A YP_961764.1 KEGG: sdy:SDY_4291 IS911 ORF2 YP_961765.1 KEGG: vch:VCA0791 transposase OrfAB, subunit B YP_961766.1 KEGG: shm:Shewmr7_2216 hypothetical protein YP_961767.1 KEGG: shm:Shewmr7_2215 hypothetical protein YP_961768.1 KEGG: noc:Noc_0575 hypothetical protein YP_961769.1 KEGG: plu:plu4649 transposase, IS4 family YP_961770.1 KEGG: noc:Noc_0575 hypothetical protein YP_961771.1 KEGG: nme:NMB1008 hypothetical protein YP_961772.1 KEGG: spd:SPD_0493 hypothetical protein YP_961773.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_961774.1 KEGG: son:SO4244 hypothetical protein YP_961775.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6, transmembrane; KEGG: son:SO4243 rarD protein YP_961776.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: she:Shewmr4_3591 uncharacterized domain 1 YP_961777.1 KEGG: she:Shewmr4_3590 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_961778.1 SMART: Tetratricopeptide domain protein; KEGG: she:Shewmr4_3589 response regulator receiver protein YP_961779.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_961780.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_961781.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_961782.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_961783.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: shm:Shewmr7_0372 membrane protein involved in aromatic hydrocarbon degradation YP_961784.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase, FGGY; KEGG: son:SO4230 glycerol kinase YP_961785.1 KEGG: shm:Shewmr7_0374 hypothetical protein YP_961786.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_961787.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: shm:Shewmr7_0378 S-adenosyl-methyltransferase MraW YP_961788.1 PFAM: cell division protein FtsL; KEGG: she:Shewmr4_3577 cell division protein FtsL YP_961789.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: son:SO4225 peptidoglycan synthetase FtsI YP_961790.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_961791.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: son:SO4223 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanine ligase YP_961792.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_961793.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_961794.1 TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: son:SO4220 cell division protein FtsW YP_961795.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_961796.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_961797.1 PFAM: cell division protein FtsQ; Polypeptide-transport-associated domain protein, FtsQ-type; KEGG: shm:Shewmr7_0388 polypeptide-transport-associated domain protein, FtsQ-type YP_961798.1 PFAM: cell division protein FtsA; KEGG: shm:Shewmr7_0389 cell division protein FtsA YP_961799.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_961800.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_961801.1 KEGG: shm:Shewmr7_0392 hypothetical protein YP_961802.1 PFAM: peptidase M23B; KEGG: shm:Shewmr7_0393 peptidase M23B YP_961803.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_961804.1 PFAM: Bile acid:sodium symporter; KEGG: shm:Shewmr7_3800 bile acid:sodium symporter YP_961805.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_961806.1 KEGG: she:Shewmr4_3731 hypothetical protein YP_961807.1 KEGG: son:SO4522 hypothetical protein YP_961808.1 IrgA; binds ferric enterobactin; irgA gene expression is repressed by Fur and induced by the divergently transcribed upstream gene irgB; outer membrane protein; involved in iron metabolism YP_961809.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO4524 transcriptional regulator, LysR family YP_961810.1 PFAM: Patatin; KEGG: shm:Shewmr7_3804 patatin YP_961811.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_3805 transcriptional regulator, LysR family YP_961812.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: shm:Shewmr7_3806 protein of unknown function DUF6, transmembrane YP_961813.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sfr:Sfri_0790 sulphate transporter YP_961814.1 PFAM: UspA domain protein; KEGG: sfr:Sfri_0791 UspA domain protein YP_961815.1 KEGG: sil:SPO2248 DnaK suppressor protein, putative YP_961816.1 PFAM: Resolvase, N-terminal domain; KEGG: sfr:Sfri_3477 resolvase, N-terminal domain protein YP_961817.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: sfr:Sfri_3472 prevent-host-death family protein YP_961818.1 TIGRFAM: Cd(II)/Pb(II)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; KEGG: abo:ABO_1367 transcriptional regulator, MerR family YP_961819.1 KEGG: abo:ABO_1368 cation efflux system permease, putative YP_961820.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_961821.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein; KEGG: bxe:Bxe_C0885 transposase, TnpA YP_961822.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: sec:SC2060 propanediol utilization: propanol dehydrogenase YP_961823.1 PFAM: aldehyde dehydrogenase; KEGG: stm:STM2051 CoA-dependent propionaldehyde dehydrogenase YP_961824.1 KEGG: ccr:CC2181 GlcG protein, putative YP_961825.1 PFAM: Ethanolamine utilization protein EutN/carboxysome structural protein Ccml; KEGG: ssn:SSO_2069 putative propanediol utilization protein: polyhedral bodies YP_961826.1 KEGG: sec:SC2056 propanediol utilization YP_961827.1 PFAM: Propanediol utilization protein; KEGG: sec:SC2055 propanediol utilization YP_961828.1 PFAM: microcompartments protein; KEGG: stt:t0828 putative propanediol utilization protein PduK YP_961829.1 PFAM: microcompartments protein; KEGG: ssn:SSO_2065 putative propanediol utilization protein: polyhedral bodies YP_961830.1 TIGRFAM: MIP family channel proteins; PFAM: major intrinsic protein; KEGG: stm:STM2037 Propanediol utilization: propanediol diffusion facilitator YP_961831.1 TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Radical SAM domain protein; KEGG: ecc:c4538 putative pyruvate formate-lyase 3 activating enzyme YP_961832.1 KEGG: ctc:CTC00936 formate acetyltransferase 2; TIGRFAM: pyruvate formate-lyase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL YP_961833.1 PFAM: microcompartments protein; KEGG: sec:SC2047 propanediol utilization: polyhedral bodies YP_961834.1 PFAM: microcompartments protein; KEGG: ssn:SSO_2058 putative propanediol utilization protein: polyhedral bodies YP_961835.1 TIGRFAM: PTS system, mannose/fructose/sorbose family, IID subunit; PFAM: PTS system mannose/fructose/sorbose family IID component; KEGG: bsu:BG10319 PTS fructose-specific enzyme IID component YP_961836.1 TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC subunit; PFAM: phosphotransferase system PTS, sorbose-specific IIC subunit; KEGG: bld:BLi02829 PTS fructose-specific enzyme IIC component; RBL00186 YP_961837.1 PFAM: PTS system sorbose subfamily IIB component; KEGG: bsu:BG10317 PTS fructose-specific enzyme IIB component YP_961838.1 PFAM: transposase, IS4 family protein; KEGG: sgl:SG1040 transposase YP_961839.1 PFAM: IS1 transposase; KEGG: sec:SC1834 IS1 transposase YP_961840.1 PFAM: phage integrase family protein; KEGG: ecc:c0291 hypothetical protein YP_961841.1 KEGG: sbo:SBO_P069 IS630 ORF YP_961842.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: stm:STM2036 Propanediol utilization: transcriptional regulation, AraC family YP_961843.1 TIGRFAM: Cd(II)/Pb(II)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; KEGG: abo:ABO_1367 transcriptional regulator, MerR family YP_961844.1 KEGG: abo:ABO_1368 cation efflux system permease, putative YP_961845.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_961846.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein; KEGG: bxe:Bxe_C0885 transposase, TnpA YP_961847.1 PFAM: transposase Tn3 family protein; KEGG: sfr:Sfri_3470 transposase Tn3 family protein YP_961848.1 TIGRFAM: RNA methyltransferase, TrmH family, group 2; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: shm:Shewmr7_3807 RNA methyltransferase, TrmH family, group 2 YP_961849.1 KEGG: she:Shewmr4_0915 hypothetical protein YP_961850.1 KEGG: she:Shewmr4_0329 hypothetical protein YP_961851.1 KEGG: she:Shewmr4_3739 hypothetical protein YP_961852.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: son:SO4537 peptidase, putative YP_961853.1 PFAM: peptidase M16 domain protein; KEGG: shm:Shewmr7_3814 peptidase M16 domain protein YP_961854.1 PFAM: peptidase M16 domain protein; KEGG: shm:Shewmr7_3815 peptidase M16 domain protein YP_961855.1 PFAM: cyclic nucleotide-binding; KEGG: son:SO4298 cyclic nucleotide binding protein, putative YP_961856.1 PFAM: purine and other phosphorylases, family 1; KEGG: son:SO4297 uridine phosphorylase, putative YP_961857.1 PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: son:SO4296 NupC family protein YP_961858.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: son:SO4295 NAD(P)H dehydrogenase (quinone) YP_961859.1 TIGRFAM: flagellar biosynthesis protein FlhA; PFAM: type III secretion FHIPEP protein; KEGG: sdn:Sden_3668 flagellar biosynthesis protein FlhA YP_961860.1 TIGRFAM: flagellar biosynthetic protein FlhB; PFAM: type III secretion exporter; KEGG: sdn:Sden_3667 flagellar biosynthetic protein FlhB YP_961861.1 TIGRFAM: flagellar biosynthetic protein FliR; PFAM: type III secretion system inner membrane R protein; KEGG: sdn:Sden_3666 flagellar biosynthetic protein FliR YP_961862.1 TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ, family 3; KEGG: sdn:Sden_3665 export protein FliQ, family 3 YP_961863.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_961864.1 TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; KEGG: sdn:Sden_3663 surface presentation of antigens (SpoA) protein YP_961865.1 KEGG: sdn:Sden_3662 hypothetical protein YP_961866.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: sdn:Sden_3661 sigma-54 factor, interaction region YP_961867.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: sdn:Sden_3660 flagellar hook-basal body complex protein (FliE) YP_961868.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; the Vibrio parahaemolyticus protein is associated with the lateral flagella YP_961869.1 One of three proteins involved in switching the direction of the flagellar rotation YP_961870.1 binds to and inhibits the function of flagella specific ATPase FliI YP_961871.1 KEGG: sdn:Sden_3656 ATPase FliI/YscN; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; H+-transporting two-sector ATPase, alpha/beta subunit domain protein; SMART: AAA ATPase YP_961872.1 KEGG: sdn:Sden_3655 hypothetical protein YP_961873.1 KEGG: sdn:Sden_3654 hypothetical protein YP_961874.1 KEGG: sdn:Sden_3653 hypothetical protein YP_961875.1 PFAM: SAF domain; KEGG: sdn:Sden_3652 flageller protein FlgA YP_961876.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_961877.1 TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: protein of unknown function DUF1078 domain protein; KEGG: sdn:Sden_3650 flagellar basal-body rod protein FlgC YP_961878.1 PFAM: flagellar hook capping protein; KEGG: sdn:Sden_3649 flagellar hook capping protein YP_961879.1 the hook connects flagellar basal body to the flagellar filament; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_961880.1 TIGRFAM: flagellar basal-body rod protein FlgF; PFAM: flagellar basal body rod protein; KEGG: sdn:Sden_3647 flagellar basal-body rod FlgF YP_961881.1 TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: sdn:Sden_3646 flagellar basal-body rod FlgG YP_961882.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_961883.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_961884.1 FlgJ; flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; like the lateral flagella FlgJ in Vibrio parahaemolyticus this protein does not contains a C-terminal muramidase domain YP_961885.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; KEGG: sdn:Sden_3642 flagellar hook-associated protein YP_961886.1 TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: sdn:Sden_3641 flagellin-like protein YP_961887.1 KEGG: sdn:Sden_3640 hypothetical protein YP_961888.1 PFAM: flagellin domain protein; KEGG: sdn:Sden_3639 flagellin-like protein YP_961889.1 PFAM: flagellin domain protein; KEGG: sdn:Sden_3639 flagellin-like protein YP_961890.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; KEGG: sdn:Sden_3638 flagellar hook-associated 2-like protein YP_961891.1 PFAM: flagellar protein FliS; KEGG: sdn:Sden_3637 flagellar protein FliS YP_961892.1 KEGG: sdn:Sden_3636 hypothetical protein YP_961893.1 PFAM: flagellar hook-length control protein; KEGG: sdn:Sden_3635 flagellar hook-length control protein YP_961894.1 PFAM: flagellar basal body-associated protein FliL; KEGG: sdn:Sden_3634 flagellar basal body-associated protein FliL YP_961895.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_961896.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: sdn:Sden_3632 MotA/TolQ/ExbB proton channel YP_961897.1 PFAM: OmpA/MotB domain protein; KEGG: sdn:Sden_3631 OmpA/MotB YP_961898.1 PFAM: type IV pilus assembly PilZ; KEGG: sdn:Sden_3630 type IV pilus assembly PilZ YP_961899.1 KEGG: sdn:Sden_3629 hypothetical protein YP_961900.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_961901.1 TIGRFAM: putative TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase, DuS; dihydroorotate dehydrogenase; KEGG: son:SO0394 tRNA-dihydrouridine synthase B YP_961902.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_961903.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit YP_961904.1 PFAM: fumarate reductase respiratory complex, transmembrane subunit; KEGG: she:Shewmr4_0403 fumarate reductase respiratory complex, transmembrane subunit YP_961905.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_961906.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_961907.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: she:Shewmr4_0406 antibiotic biosynthesis monooxygenase YP_961908.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: son:SO0401 alcohol dehydrogenase, zinc-containing YP_961909.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_0408 transcriptional regulator, LysR family YP_961910.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_961911.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: shm:Shewmr7_3615 thioredoxin YP_961912.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_961913.1 PFAM: Ppx/GppA phosphatase; KEGG: shm:Shewmr7_3613 Ppx/GppA phosphatase YP_961914.1 KEGG: shm:Shewmr7_3612 hypothetical protein YP_961915.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: she:Shewmr4_0414 mutator MutT protein YP_961916.1 PFAM: protein of unknown function DUF329; KEGG: shm:Shewmr7_3610 protein of unknown function DUF329 YP_961917.1 PFAM: protein of unknown function DUF1342; KEGG: she:Shewmr4_0416 protein of unknown function DUF1342 YP_961918.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_961919.1 PFAM: peptidase A24A, prepilin type IV; peptidase A24A domain protein; KEGG: son:SO0414 leader peptidase (prepilin peptidase) / N-methyltransferase YP_961920.1 PFAM: type II secretion system protein; KEGG: shm:Shewmr7_3606 type II secretion system protein YP_961921.1 TIGRFAM: type IV-A pilus assembly ATPase PilB; PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; KEGG: son:SO0416 type IV pilus biogenesis protein PilB YP_961922.1 KEGG: par:Psyc_0240 probable pilus assembly protein major pilin PilA YP_961923.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein; KEGG: bxe:Bxe_C0885 transposase, TnpA YP_961924.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_961925.1 KEGG: abo:ABO_1368 cation efflux system permease, putative YP_961926.1 TIGRFAM: Cd(II)/Pb(II)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; KEGG: abo:ABO_1367 transcriptional regulator, MerR family YP_961927.1 KEGG: shm:Shewmr7_3603 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase YP_961928.1 PFAM: N-acetylmuramoyl-L-alanine amidase, family 2; KEGG: son:SO0421 AmpD protein YP_961929.1 involved in regulation of beta-lactamase; putative signaling protein YP_961930.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_961931.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_961932.1 KEGG: son:SO0425 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_961933.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_961934.1 KEGG: she:Shewmr4_0431 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_961935.1 PFAM: surface antigen (D15); Patatin; KEGG: she:Shewmr4_0432 patatin YP_961936.1 PFAM: peptidase M13, neprilysin; peptidase M13; KEGG: son:SO0429 peptidase, M13 family YP_961937.1 KEGG: son:SO0430 hypothetical protein YP_961938.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_961939.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_961940.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_961942.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_961943.1 KEGG: son:SO0437 sensory box protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_961944.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_3588 short-chain dehydrogenase/reductase SDR YP_961945.1 KEGG: shm:Shewmr7_3587 hypothetical protein YP_961946.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_961947.1 involved in de novo purine biosynthesis YP_961948.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_961949.1 PFAM: permease; KEGG: son:SO0444 hypothetical protein YP_961950.1 PFAM: band 7 protein; KEGG: shm:Shewmr7_3581 band 7 protein YP_961951.1 KEGG: son:SO0447 hypothetical protein YP_961952.1 KEGG: son:SO0448 hypothetical protein YP_961953.1 PFAM: PepSY-associated TM helix domain protein; KEGG: shm:Shewmr7_3578 PepSY-associated TM helix domain protein YP_961954.1 PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_0452 major facilitator superfamily MFS_1 YP_961955.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: she:Shewmr4_0455 anion transporter YP_961956.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: son:SO0452 thioredoxin 2 YP_961957.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO0453 peptidyl-prolyl cis-trans isomerase FkbP YP_961958.1 KEGG: she:Shewmr4_0458 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein YP_961960.1 KEGG: shm:Shewmr7_2786 hypothetical protein YP_961961.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: sfr:Sfri_3694 twin-arginine translocation pathway signal YP_961962.1 PFAM: Tannase and feruloyl esterase; KEGG: sfr:Sfri_3696 feruloyl esterase YP_961963.1 PFAM: outer membrane porin; KEGG: shm:Shewmr7_2788 outer membrane porin YP_961964.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: shm:Shewmr7_2789 regulatory protein GntR, HTH YP_961965.1 KEGG: she:Shewmr4_0459 hypothetical protein YP_961966.1 TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: she:Shewmr4_0460 TRAP transporter, 4TM/12TM fusion protein YP_961967.1 TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: she:Shewmr4_0461 TRAP transporter solute receptor, TAXI family YP_961968.1 KEGG: shm:Shewmr7_3567 hypothetical protein YP_961969.1 PFAM: protein of unknown function DUF853, NPT hydrolase putative; KEGG: shm:Shewmr7_3566 protein of unknown function DUF853, NPT hydrolase putative YP_961970.1 PFAM: NUDIX hydrolase; KEGG: son:SO0464 MutT/nudix family protein YP_961971.1 KEGG: psb:Psyr_3988 hypothetical protein YP_961972.1 PFAM: glycosyl transferase, family 51; KEGG: bja:bll0910 penicillin-binding protein YP_961973.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_961974.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_961975.1 PFAM: 2-nitropropane dioxygenase, NPD; KEGG: she:Shewmr4_0476 2-nitropropane dioxygenase, NPD YP_961976.1 PFAM: protein of unknown function UPF0118; KEGG: she:Shewmr4_0479 protein of unknown function UPF0118 YP_961977.1 KEGG: shm:Shewmr7_3550 putative mitomycin resistance protein YP_961978.1 KEGG: son:SO0474 hypothetical protein YP_961979.1 PFAM: Redoxin domain protein; KEGG: shm:Shewmr7_3545 redoxin domain protein YP_961980.1 PFAM: cytochrome C biogenesis protein; KEGG: shm:Shewmr7_3544 cytochrome c biogenesis protein YP_961981.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: son:SO0478 cytochrome c-type biogenesis protein CcmF YP_961982.1 KEGG: she:Shewmr4_0488 cytochrome c, putative YP_961983.1 SMART: Rhodanese domain protein; KEGG: shm:Shewmr7_3541 rhodanese domain protein YP_961984.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type; KEGG: she:Shewmr4_0490 FKBP-type peptidyl-prolyl isomerase domain protein YP_961985.1 KEGG: son:SO0482 formate-dependent nitrite reductase, NrfG protein YP_961986.1 PFAM: NosL family protein; KEGG: son:SO0485 NosL protein YP_961987.1 PFAM: periplasmic copper-binding; SMART: Parallel beta-helix repeat; Carbohydrate-binding and sugar hydrolysis; KEGG: son:SO0486 copper ABC transporter, periplasmic copper-binding protein YP_961988.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0487 copper ABC transporter, ATP-binding protein YP_961989.1 KEGG: son:SO0488 copper ABC transporter, permease protein YP_961990.1 PFAM: transcriptional regulator domain protein; KEGG: shm:Shewmr7_3532 transcriptional regulator, CadC YP_961991.1 KEGG: she:Shewmr4_0502 conserved hypothetical flavoprotein oxygenase YP_961993.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_961994.1 TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: shm:Shewmr7_3525 UbiD family decarboxylases YP_961995.1 KEGG: she:Shewmr4_0507 hypothetical protein YP_961997.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: shm:Shewmr7_3522 short-chain dehydrogenase/reductase SDR YP_961998.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_961999.1 PFAM: Class I peptide chain release factor; KEGG: son:SO0513 hypothetical protein YP_962000.1 KEGG: son:SO0514 hypothetical protein YP_962001.1 KEGG: shm:Shewmr7_3517 hypothetical protein YP_962002.1 KEGG: she:Shewmr4_0515 hypothetical protein YP_962003.1 KEGG: shm:Shewmr7_3515 outer membrane efflux protein YP_962004.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO0519 cation efflux protein, putative YP_962005.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_3513 heavy metal efflux pump, CzcA family YP_962006.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: son:SO0521 hypothetical protein YP_962007.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_962008.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_0525 GCN5-related N-acetyltransferase YP_962009.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: son:SO0527 hypothetical protein YP_962010.1 KEGG: shm:Shewmr7_3496 redox-active disulfide protein 2 YP_962011.1 KEGG: son:SO0540 hypothetical protein YP_962012.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: son:SO0541 metallo-beta-lactamase family protein YP_962013.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: sdn:Sden_0649 amino acid carrier protein YP_962014.1 PFAM: protein of unknown function DUF1704; KEGG: son:SO0542 hypothetical protein YP_962015.1 KEGG: shm:Shewmr7_3488 hypothetical protein YP_962016.1 KEGG: she:Shewmr4_0543 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; CHASE domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_962017.1 PFAM: response regulator receiver; KEGG: she:Shewmr4_0544 response regulator receiver protein YP_962018.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; KEGG: son:SO0545 response regulator YP_962019.1 TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: son:SO0546 ribosomal protein S6 modification protein YP_962020.1 KEGG: she:Shewmr4_0547 hypothetical protein YP_962021.1 PFAM: histone family protein DNA-binding protein; KEGG: she:Shewmr4_0548 histone family protein DNA-binding protein YP_962022.1 PFAM: response regulator receiver; KEGG: shm:Shewmr7_3481 response regulator receiver protein YP_962023.1 KEGG: son:SO0550 hypothetical protein YP_962024.1 KEGG: shm:Shewmr7_3479 hypothetical protein YP_962025.1 KEGG: shm:Shewmr7_3477 hypothetical protein YP_962026.1 KEGG: shm:Shewmr7_3476 hypothetical protein YP_962027.1 PFAM: GGDEF domain containing protein; CBS domain containing protein; EAL domain protein; KEGG: shm:Shewmr7_3475 diguanylate cyclase/phosphodiesterase YP_962028.1 KEGG: shm:Shewmr7_3474 hypothetical protein YP_962029.1 PFAM: GumN family protein; KEGG: son:SO0557 hypothetical protein YP_962030.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO0558 smtA protein YP_962031.1 PFAM: MaoC domain protein dehydratase; KEGG: son:SO0559 MaoC domain protein YP_962032.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_962033.1 KEGG: she:Shewmr4_0564 hypothetical protein YP_962034.1 KEGG: shm:Shewmr7_3465 hypothetical protein YP_962035.1 KEGG: shm:Shewmr7_3464 hypothetical protein YP_962036.1 PFAM: periplasmic solute binding protein; KEGG: shm:Shewmr7_3463 periplasmic solute binding protein YP_962037.1 PFAM: ABC-3 protein; KEGG: shm:Shewmr7_3462 ABC-3 protein YP_962038.1 KEGG: she:Shewmr4_0569 1-acyl-sn-glycerol-3-phosphate acyltransferases; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; PFAM: phospholipid/glycerol acyltransferase YP_962039.1 PFAM: protein of unknown function DUF1260; KEGG: shm:Shewmr7_3460 protein of unknown function DUF1260 YP_962040.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_3459 diguanylate cyclase YP_962041.1 PFAM: response regulator receiver; KEGG: son:SO0570 response regulator YP_962042.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_962043.1 KEGG: son:SO0573 hypothetical protein YP_962044.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_962045.1 PFAM: PhoH family protein; SMART: AAA ATPase; Nucleotide binding protein, PINc; KEGG: shm:Shewmr7_3454 PhoH family protein YP_962046.1 KEGG: she:Shewmr4_0577 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Cache domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_962047.1 KEGG: son:SO0578 hypothetical protein YP_962048.1 PFAM: protein kinase; SMART: serine/threonine protein kinase; KEGG: shm:Shewmr7_3451 serine/threonine protein kinase YP_962049.1 KEGG: she:Shewmr4_0580 hypothetical protein YP_962050.1 catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide YP_962051.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: she:Shewmr4_0582 BFD domain protein (2Fe-2S)-binding domain protein YP_962052.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; KEGG: shm:Shewmr7_3447 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor YP_962053.1 KEGG: shm:Shewmr7_3445 hypothetical protein YP_962054.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: shm:Shewmr7_3444 glycerophosphoryl diester phosphodiesterase YP_962055.1 PFAM: MscS Mechanosensitive ion channel; KEGG: she:Shewmr4_0587 MscS mechanosensitive ion channel YP_962056.1 PFAM: protein of unknown function DUF6, transmembrane; UAA transporter; KEGG: shm:Shewmr7_3442 protein of unknown function DUF6, transmembrane YP_962057.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_962058.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_962059.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_962060.1 KEGG: shm:Shewmr7_3438 hypothetical protein YP_962061.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family N-terminal domain protein; KEGG: she:Shewmr4_0593 carbohydrate kinase, YjeF related protein YP_962062.1 PFAM: protein of unknown function UPF0079; KEGG: son:SO0599 conserved hypothetical protein TIGR00150 YP_962063.1 PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: she:Shewmr4_0595 N-acetylmuramoyl-L-alanine amidase YP_962064.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_962065.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_962066.1 TIGRFAM: RNA chaperone Hfq; PFAM: Like-Sm ribonucleoprotein, core; KEGG: shm:Shewmr7_3432 RNA chaperone Hfq YP_962067.1 PFAM: GTP-binding protein, HSR1-related; KEGG: son:SO0604 GTP-binding protein HflX YP_962068.1 TIGRFAM: HflK protein; PFAM: band 7 protein; KEGG: she:Shewmr4_0600 HflK protein YP_962069.1 TIGRFAM: HflC protein; PFAM: band 7 protein; KEGG: shm:Shewmr7_3429 HflC protein YP_962070.1 KEGG: shm:Shewmr7_3428 ubiquinol-cytochrome c reductase, iron-sulfur subunit; TIGRFAM: ubiquinol-cytochrome c reductase, iron-sulfur subunit; PFAM: Rieske [2Fe-2S] domain protein YP_962071.1 PFAM: Cytochrome b/b6, N-terminal domain; Cytochrome b/b6, C-terminal domain; KEGG: son:SO0609 ubiquinol-cytochrome c reductase, cytochrome b YP_962072.1 PFAM: cytochrome c1; KEGG: shm:Shewmr7_3426 cytochrome c1 YP_962073.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_962074.1 PFAM: Stringent starvation protein B; KEGG: shm:Shewmr7_3424 stringent starvation protein B YP_962075.1 KEGG: she:Shewmr4_3418 hypothetical protein YP_962076.1 PFAM: helix-turn-helix- domain containing protein, AraC type; response regulator receiver; KEGG: cps:CPS_0756 sensory box sensor histidine kinase/DNA-binding response regulator, AraC family YP_962077.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: cvi:CV0964 hypothetical protein YP_962078.1 KEGG: mhu:Mhun_1163 PKD YP_962079.1 PFAM: PKD domain containing protein; protein of unknown function DUF1566; KEGG: pat:Patl_3292 protein of unknown function DUF1566 YP_962080.1 PFAM: protein of unknown function DUF1566; KEGG: pat:Patl_3291 protein of unknown function DUF1566 YP_962081.1 PFAM: protein of unknown function DUF1566; KEGG: pat:Patl_3291 protein of unknown function DUF1566 YP_962082.1 KEGG: wsu:WS1457 hypothetical protein YP_962084.1 PFAM: peptidase M16 domain protein; KEGG: son:SO4022 peptidase, M16 family YP_962085.1 KEGG: son:SO4020 transcriptional regulator, LysR family YP_962086.1 PFAM: GCN5-related N-acetyltransferase; KEGG: vfi:VFA0653 IAA acetyltransferase YP_962087.1 KEGG: son:SO4019 hypothetical protein YP_962088.1 KEGG: she:Shewmr4_3415 hypothetical protein YP_962089.1 PFAM: Peptidoglycan-binding LysM; Lytic transglycosylase, catalytic; MLTD_N domain protein; KEGG: son:SO4017 transglycosylase, Slt family YP_962090.1 PFAM: protein kinase; leucine-rich repeat protein; SMART: tyrosine protein kinase; serine/threonine protein kinase; leucine-rich repeat-containing protein, typical subtype; KEGG: son:SO4016 hypothetical protein YP_962091.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO4015 hypothetical protein YP_962092.1 PFAM: acriflavin resistance protein; KEGG: son:SO4014 AcrB/AcrD/AcrF family protein YP_962093.1 KEGG: son:SO4013 hypothetical protein YP_962094.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: son:SO0640 alcohol dehydrogenase, zinc-containing YP_962095.1 KEGG: son:SO0691 hypothetical protein YP_962096.1 PFAM: Aldose 1-epimerase; KEGG: son:SO0693 aldose 1-epimerase YP_962097.1 KEGG: she:Shewmr4_3408 galactokinase; TIGRFAM: galactokinase; PFAM: GHMP kinase; GHMP kinase, C terminal domain protein YP_962098.1 PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: son:SO0695 glutathione-regulated potassium-efflux system protein KefC, putative YP_962099.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_962100.1 PFAM: CutA1 divalent ion tolerance protein; KEGG: shm:Shewmr7_0547 CutA1 divalent ion tolerance protein YP_962101.1 PFAM: FxsA cytoplasmic membrane protein; KEGG: shm:Shewmr7_0548 FxsA cytoplasmic membrane protein YP_962102.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: bbr:BB1960 hypothetical protein YP_962103.1 KEGG: shm:Shewmr7_0573 hypothetical protein YP_962104.1 PFAM: isochorismatase hydrolase; KEGG: she:Shewmr4_3363 isochorismatase hydrolase YP_962105.1 PFAM: nitrogen regulatory protein P-II; KEGG: son:SO0761 nitrogen regulatory protein P-II 1 YP_962106.1 PFAM: Rh family protein/ammonium transporter; KEGG: shm:Shewmr7_0592 Rh family protein/ammonium transporter YP_962107.1 KEGG: shm:Shewmr7_0593 hypothetical protein YP_962108.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_962109.1 KEGG: shm:Shewmr7_0596 hypothetical protein YP_962110.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0754 ABC transporter, ATP-binding protein YP_962111.1 KEGG: shm:Shewmr7_0598 hypothetical protein YP_962112.1 KEGG: son:SO0752 hypothetical protein YP_962113.1 PFAM: ferredoxin-dependent glutamate synthase; KEGG: shm:Shewmr7_0600 ferredoxin-dependent glutamate synthase YP_962114.1 PFAM: Phosphoglycerate mutase; KEGG: son:SO0749 hypothetical protein YP_962115.1 KEGG: son:SO0748 hypothetical protein YP_962116.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: son:SO0747 ferredoxin--NADP reductase YP_962117.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: shm:Shewmr7_0604 glutathione S-transferase, N-terminal domain protein YP_962118.1 KEGG: shm:Shewmr7_0605 hypothetical protein YP_962119.1 PFAM: extracellular solute-binding protein, family 1; KEGG: son:SO0744 iron(III) ABC transporter, periplasmic iron(III)-binding protein YP_962120.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO0743 iron(III) ABC transporter, permease protein YP_962121.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_0608 ABC transporter related YP_962122.1 KEGG: shm:Shewmr7_0609 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_962123.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: son:SO0740 melanin biosynthesis protein TyrA, putative YP_962124.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_0611 transcriptional regulator, LysR family YP_962125.1 PFAM: NAD-dependent epimerase/dehydratase; NmrA family protein; KEGG: shm:Shewmr7_0612 NAD-dependent epimerase/dehydratase YP_962126.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_962127.1 oxidizes malate to oxaloacetate YP_962128.1 PFAM: putative thiol-disulphide oxidoreductase DCC; KEGG: son:SO0771 hypothetical protein YP_962129.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: son:SO0772 oxidoreductase, short chain dehydrogenase/reductase family YP_962130.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: she:Shewmr4_3336 5-formyltetrahydrofolate cyclo-ligase YP_962131.1 PFAM: protein of unknown function DUF710; KEGG: son:SO0775 hypothetical protein YP_962132.1 TIGRFAM: yecA family protein; PFAM: protein of unknown function UPF0149; KEGG: shm:Shewmr7_0619 YecA family protein YP_962133.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; 2-polyprenyl-6-methoxyphenol 4-hydroxylase; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: she:Shewmr4_3333 2-polyprenyl-6-methoxyphenol 4-hydroxylase YP_962134.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: son:SO0778 oxidoreductase, FAD-binding, UbiH/Coq6 family YP_962135.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_962136.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_962137.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_962139.1 KEGG: plu:plu4649 transposase, IS4 family YP_962140.1 KEGG: san:gbs1341 hypothetical protein YP_962141.1 KEGG: san:gbs1342 hypothetical protein YP_962142.1 PFAM: NERD domain protein; KEGG: shm:Shewmr7_0627 hypothetical protein YP_962143.1 KEGG: pen:PSEEN2314 hypothetical protein YP_962144.1 KEGG: son:SO0788 hypothetical protein YP_962145.1 KEGG: son:SO0792 hypothetical protein YP_962146.1 KEGG: plu:plu4649 transposase, IS4 family YP_962147.1 KEGG: cps:CPS_2516 hypothetical protein YP_962148.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: shm:Shewmr7_3199 methyl-accepting chemotaxis sensory transducer YP_962149.1 TIGRFAM: uncharacterized domain; PFAM: OsmC family protein; protein of unknown function DUF181; KEGG: shm:Shewmr7_0632 uncharacterized domain YP_962150.1 KEGG: eba:ebA616 hypothetical protein YP_962151.1 KEGG: eba:ebB16 hypothetical protein YP_962153.1 KEGG: rpa:RPA2335 hypothetical protein YP_962154.1 KEGG: rpa:RPA2334 hypothetical protein YP_962155.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: eba:ebA609 putative cation transport ATPase YP_962156.1 KEGG: she:Shewmr4_3319 hypothetical protein YP_962157.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_3318 TonB-dependent receptor YP_962158.1 PFAM: protein of unknown function DUF985; KEGG: shm:Shewmr7_0636 protein of unknown function DUF985 YP_962159.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_962160.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: shm:Shewmr7_0637 alpha/beta hydrolase fold-3 domain protein YP_962161.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: shm:Shewmr7_0638 MATE efflux family protein YP_962162.1 KEGG: son:SO0804 hypothetical protein YP_962163.1 PFAM: CBS domain containing protein; KEGG: shm:Shewmr7_0640 CBS domain containing membrane protein YP_962164.1 PFAM: Alkaline phosphatase; KEGG: she:Shewmr4_3312 twin-arginine translocation pathway signal YP_962165.1 KEGG: shm:Shewmr7_0642 hypoxanthine-guanine phosphoribosyltransferase YP_962166.1 KEGG: she:Shewmr4_3309 hypothetical protein YP_962167.1 KEGG: sdn:Sden_0953 hypothetical protein YP_962168.1 TIGRFAM: Azurin; PFAM: blue (type 1) copper domain protein; KEGG: shm:Shewmr7_0645 blue (type 1) copper domain protein YP_962169.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_962170.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific YP_962171.1 KEGG: son:SO0813 hypothetical protein YP_962172.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_0651 TonB-dependent siderophore receptor YP_962173.1 KEGG: sfr:Sfri_1031 hypothetical protein YP_962174.1 PFAM: HDOD; KEGG: shm:Shewmr7_0652 putative signal transduction protein YP_962175.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_0653 transcriptional regulator, LysR family YP_962176.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_962177.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: sugar-specific permease, EIIA 1 domain; secretion protein HlyD family protein; KEGG: son:SO0820 HlyD family secretion protein YP_962178.1 PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: son:SO0821 ABC transporter, ATP-binding/permease protein YP_962179.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: son:SO0822 outer membrane efflux family protein YP_962180.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: dvu:DVU0416 GGDEF domain protein YP_962181.1 PFAM: peptidase M50; KEGG: shm:Shewmr7_0672 peptidase M50 YP_962182.1 KEGG: she:Shewmr4_3274 hypothetical protein YP_962183.1 PFAM: protein of unknown function DUF342; KEGG: she:Shewmr4_3273 protein of unknown function DUF342 YP_962184.1 PFAM: methyltransferase small; Methyltransferase small, N-terminal domain protein; KEGG: she:Shewmr4_0687 rRNA (guanine-N(2)-)-methyltransferase YP_962185.1 PFAM: Alkaline phosphatase; KEGG: shm:Shewmr7_3334 alkaline phosphatase YP_962186.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_962187.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_962188.1 PFAM: Endonuclease I; KEGG: she:Shewmr4_0691 deoxyribonuclease I YP_962189.1 PFAM: protein of unknown function DUF335, SprT; SMART: protein of unknown function SprT; KEGG: son:SO0834 sprT protein, putative YP_962190.1 KEGG: she:Shewmr4_0693 hypothetical protein YP_962191.1 PFAM: penicillin-binding protein, transpeptidase; KEGG: son:SO0837 beta-lactamase, putative YP_962192.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_0695 transcriptional regulator, LysR family YP_962193.1 PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: son:SO0840 acetyl-CoA carboxylase multifunctional enzyme accADC, carboxyl transferase subunit alpha/carboxyl transferase subunit beta/biotin carboxylase YP_962194.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_962195.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_3323 transcriptional regulator, LysR family YP_962196.1 KEGG: shm:Shewmr7_3322 hypothetical protein YP_962197.1 PFAM: Nitrate reductase cytochrome c-type subunit (NapB); KEGG: shm:Shewmr7_3321 nitrate reductase cytochrome c-type subunit (NapB) YP_962198.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA YP_962199.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway YP_962200.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_962201.1 PFAM: NapD family protein; KEGG: son:SO0849 napD protein YP_962202.1 KEGG: she:Shewmr4_0711 hypothetical protein YP_962203.1 PFAM: protein of unknown function DUF214; KEGG: son:SO0856 putative ABC transport system permease protein YP_962204.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_3309 ABC transporter related YP_962205.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: she:Shewmr4_0714 amino acid carrier protein YP_962206.1 KEGG: shm:Shewmr7_3307 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_962207.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: shm:Shewmr7_3306 response regulator receiver modulated metal dependent phosphohydrolase YP_962208.1 PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: son:SO0861 hypothetical protein YP_962209.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_962210.1 KEGG: she:Shewmr4_0719 hypothetical protein YP_962211.1 PFAM: regulatory protein, LuxR; KEGG: she:Shewmr4_0720 transcriptional regulator, LuxR family YP_962212.1 PFAM: Curlin associated repeat protein; KEGG: she:Shewmr4_0721 curlin associated repeat protein YP_962213.1 PFAM: Curlin associated repeat protein; KEGG: son:SO0866 minor curlin subunit CsgB, putative YP_962214.1 KEGG: she:Shewmr4_0724 hypothetical protein YP_962215.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_962216.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_962217.1 KEGG: son:SO0871 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK YP_962218.1 TIGRFAM: poly(A) polymerase; PFAM: Polynucleotide adenylyltransferase region; KEGG: she:Shewmr4_0728 poly(A) polymerase YP_962219.1 PFAM: glutamyl-tRNA synthetase, class Ic; KEGG: shm:Shewmr7_3293 glutamyl-tRNA synthetase, class Ic YP_962220.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger, DksA/TraR C4-type; KEGG: shm:Shewmr7_3292 transcriptional regulators, TraR/DksA family YP_962221.1 Regulatory factor involved in maltose metabolism YP_962222.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_962223.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO0877 acetyltransferase, GNAT family YP_962224.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: shm:Shewmr7_3288 phosphoribulokinase YP_962225.1 KEGG: shm:Shewmr7_3287 protein of unknown function UPF0270 YP_962226.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO0880 hypothetical protein YP_962227.1 KEGG: son:SO0881 hypothetical protein YP_962228.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: son:SO0882 oxidoreductase, GMC family YP_962229.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: son:SO0883 hypothetical protein YP_962230.1 KEGG: shm:Shewmr7_3282 hypothetical protein YP_962231.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0885 ABC transporter, ATP-binding protein YP_962232.1 KEGG: sdn:Sden_3177 hypothetical protein YP_962234.1 KEGG: son:SO1889 hypothetical protein YP_962235.1 KEGG: she:Shewmr4_2555 protein of unknown function DUF1568 YP_962236.1 KEGG: son:SO2169.1 hypothetical protein YP_962237.1 PFAM: Pirin domain protein domain protein; Pirin domain protein; KEGG: she:Shewmr4_0744 pirin domain protein domain protein YP_962238.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_962239.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; KEGG: pen:PSEEN3931 aerotaxis receptor YP_962240.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: she:Shewmr4_3129 DEAD/DEAH box helicase domain protein YP_962241.1 KEGG: shm:Shewmr7_0839 hypothetical protein YP_962242.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_962243.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_962244.1 TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: son:SO3778 adenylate cyclase CyaB, putative YP_962245.1 KEGG: son:SO3777 hypothetical protein YP_962246.1 PFAM: protein of unknown function DUF599; KEGG: son:SO3776 hypothetical protein YP_962249.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain YP_962250.1 PFAM: SH3, type 3 domain protein; SMART: SH3 domain protein domain protein; KEGG: shm:Shewmr7_0851 SH3 domain protein domain protein YP_962251.1 PFAM: phosphate transporter; KEGG: she:Shewmr4_3120 phosphate transporter YP_962252.1 PFAM: protein of unknown function DUF47; KEGG: shm:Shewmr7_0853 protein of unknown function DUF47 YP_962253.1 PFAM: adenylate cyclase; KEGG: she:Shewmr4_3118 adenylate cyclase YP_962254.1 PFAM: Ion transport protein; Ion transport 2 domain protein,; KEGG: son:SO3768 ion transporter YP_962255.1 KEGG: shm:Shewmr7_0856 hypothetical protein YP_962256.1 KEGG: son:SO3766 hypothetical protein YP_962257.1 PFAM: PspA/IM30 family protein; KEGG: son:SO3765 hypothetical protein YP_962258.1 KEGG: shm:Shewmr7_0859 hypothetical protein YP_962259.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_962260.1 KEGG: shm:Shewmr7_0861 protein of unknown function DUF350 YP_962261.1 KEGG: she:Shewmr4_3110 hypothetical protein YP_962262.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_962263.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: shm:Shewmr7_0864 diguanylate cyclase with GAF sensor YP_962264.1 PFAM: protein of unknown function DUF897; KEGG: she:Shewmr4_3107 protein of unknown function DUF897 YP_962265.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO3757 rubisco operon transcriptional regulator YP_962266.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_962267.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; K+-transporting ATPase, B subunit; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: xcb:XC_3531 potassium-transporting ATPase B chain YP_962268.1 PFAM: K+ transporting ATPase, KdpC subunit; KEGG: tte:TTE2010 K+-transporting ATPase, c chain YP_962269.1 PFAM: K+ transporting ATPase, KdpC subunit; KEGG: aci:ACIAD2976 potassium-transporting ATPase C chain YP_962270.1 KEGG: pfo:Pfl_3155 hypothetical protein YP_962271.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Osmosensitive K+ channel His kinase sensor; KEGG: xom:XOO_3621 two-component system sensor protein YP_962272.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: psb:Psyr_2051 response regulator receiver:transcriptional regulatory protein, C-terminal YP_962273.1 PFAM: AFG1-family ATPase; KEGG: she:Shewmr4_3102 AFG1-family ATPase YP_962274.1 KEGG: shm:Shewmr7_0880 hypothetical protein YP_962275.1 PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: son:SO3748 LysM domain protein YP_962276.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_962277.1 KEGG: shm:Shewmr7_0883 putative nitric oxide reductase (subunit B) transmembrane protein YP_962278.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_962279.1 TIGRFAM: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; PFAM: lipid A biosynthesis acyltransferase; KEGG: son:SO3746 lipid A biosynthesis lauroyl acyltransferase YP_962280.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_962281.1 KEGG: son:SO3744 hypothetical protein YP_962282.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_0888 transcriptional regulator, TetR family YP_962283.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_962284.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_962285.1 TIGRFAM: sulfite reductase [NADPH] flavoprotein, alpha chain; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; flavodoxin/nitric oxide synthase; KEGG: she:Shewmr4_3080 sulfite reductase (NADPH) flavoprotein, alpha chain YP_962286.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_962287.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_962288.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_962289.1 KEGG: son:SO3733 hypothetical protein YP_962290.1 KEGG: shm:Shewmr7_3211 hypothetical protein YP_962291.1 KEGG: son:SO0975 hypothetical protein YP_962292.1 PFAM: OsmC family protein; KEGG: shm:Shewmr7_3209 OsmC family protein YP_962293.1 PFAM: regulatory protein, MarR; KEGG: she:Shewmr4_0815 transcriptional regulator, MarR family YP_962294.1 PFAM: FAD dependent oxidoreductase; KEGG: shm:Shewmr7_3207 FAD dependent oxidoreductase YP_962295.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_962296.1 TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter; KEGG: she:Shewmr4_0823 chromate transporter, chromate ion transporter (CHR) family YP_962297.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: shm:Shewmr7_3199 methyl-accepting chemotaxis sensory transducer YP_962298.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: shm:Shewmr7_3198 formate dehydrogenase, alpha subunit YP_962299.1 TIGRFAM: peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein; KEGG: shm:Shewmr7_3197 peptide chain release factor 2 YP_962300.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_962301.1 KEGG: son:SO0994 hypothetical protein YP_962302.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_962303.1 PFAM: peptidase S41; KEGG: she:Shewmr4_3075 hypothetical protein YP_962304.1 PFAM: phospholipase A1; KEGG: shm:Shewmr7_0898 phospholipase A(1) YP_962305.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: shm:Shewmr7_0899 uroporphyrin-III C-methyltransferase YP_962306.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_962307.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_962308.1 PFAM: Citrate transporter; TrkA-C domain protein; KEGG: shm:Shewmr7_0902 TrkA-C domain protein YP_962309.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_962310.1 KEGG: shm:Shewmr7_0904 hypothetical protein YP_962311.1 KEGG: shm:Shewmr7_0906 protoporphyrinogen oxidase YP_962312.1 KEGG: son:SO3719 hypothetical protein YP_962313.1 PFAM: DSBA oxidoreductase; KEGG: shm:Shewmr7_0909 DsbA oxidoreductase YP_962314.1 PFAM: heat shock protein DnaJ domain protein; KEGG: shm:Shewmr7_0910 heat shock protein DnaJ domain protein YP_962315.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive YP_962316.1 KEGG: son:SO1508 hypothetical protein YP_962317.1 KEGG: rba:RB954 hypothetical protein YP_962318.1 KEGG: pfl:PFL_3339 hypothetical protein YP_962320.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_0917 ABC transporter related YP_962321.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO1043 amino acid ABC transporter, permease protein YP_962322.1 PFAM: extracellular solute-binding protein, family 3; KEGG: shm:Shewmr7_0919 extracellular solute-binding protein, family 3 YP_962323.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO1046 transcriptional regulator, LysR family YP_962324.1 PFAM: LrgA family protein; KEGG: shm:Shewmr7_0922 LrgA family protein YP_962325.1 PFAM: LrgB family protein; KEGG: shm:Shewmr7_0923 LrgB family protein YP_962326.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1049 acetyltransferase, GNAT family YP_962327.1 PFAM: carbon starvation protein CstA; KEGG: shm:Shewmr7_0925 carbon starvation protein CstA YP_962328.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_962329.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_962330.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: vpa:VPA1697 putative transcriptional regulator YP_962331.1 PFAM: phosphate transporter; KEGG: shm:Shewmr7_0927 phosphate transporter YP_962332.1 PFAM: protein of unknown function DUF72; KEGG: shm:Shewmr7_0928 protein of unknown function DUF72 YP_962333.1 KEGG: shm:Shewmr7_0929 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_962334.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: son:SO1056 methyl-accepting chemotaxis protein YP_962335.1 KEGG: plu:plu4649 transposase, IS4 family YP_962336.1 KEGG: shm:Shewmr7_0930 methyl-accepting chemotaxis sensory transducer YP_962337.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: shm:Shewmr7_0932 aminopeptidase N YP_962338.1 TIGRFAM: membrane lipoprotein lipid attachment site; KEGG: shm:Shewmr7_0935 hypothetical protein YP_962339.1 PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: son:SO1061 TPR domain protein YP_962340.1 KEGG: she:Shewmr4_3037 peptide deformylase; TIGRFAM: peptide deformylase; PFAM: formylmethionine deformylase YP_962341.1 PFAM: SlyX family protein; KEGG: she:Shewmr4_3036 SlyX family protein YP_962342.1 PFAM: WD-40 repeat protein; KEGG: son:SO1064 hypothetical WD domain protein YP_962343.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type; KEGG: she:Shewmr4_3034 peptidylprolyl isomerase, FKBP-type YP_962344.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: she:Shewmr4_3033 endonuclease/exonuclease/phosphatase YP_962345.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_0943 uncharacterized domain 1 YP_962346.1 KEGG: sdn:Sden_3091 hypothetical protein YP_962347.1 PFAM: dienelactone hydrolase; KEGG: son:SO1006 dienelactone hydrolase family protein YP_962348.1 PFAM: Abortive infection protein; KEGG: pat:Patl_0909 hypothetical protein YP_962349.1 KEGG: son:SO3708 hypothetical protein YP_962350.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: rxy:Rxyl_0136 transcriptional regulator, GntR family YP_962351.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mxa:MXAN_1748 acetyltransferase, GNAT family YP_962352.1 KEGG: she:Shewmr4_0079 MORN variant repeat protein YP_962353.1 KEGG: zmo:ZMO1197 glutamate racemase; TIGRFAM: glutamate racemase; PFAM: Asp/Glu racemase YP_962355.1 KEGG: shm:Shewmr7_3165 hypothetical protein YP_962356.1 KEGG: son:SO3696 hypothetical protein YP_962357.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_962358.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: she:Shewmr4_0861 efflux transporter, RND family, MFP subunit YP_962359.1 KEGG: shm:Shewmr7_3160 hypothetical protein YP_962360.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_3159 ABC transporter related YP_962361.1 PFAM: protein of unknown function DUF214; KEGG: sdn:Sden_2849 protein of unknown function DUF214 YP_962362.1 PFAM: protein of unknown function DUF214; KEGG: sfr:Sfri_0900 protein of unknown function DUF214 YP_962363.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: she:Shewmr4_0866 two component, sigma54 specific, transcriptional regulator, fis family YP_962364.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO3688 nitrogen regulation protein NtrY, putative YP_962365.1 KEGG: she:Shewmr4_0868 curli production assembly/transport component CsgE, putative YP_962366.1 KEGG: she:Shewmr4_0869 curli production assembly/transport component CsgF, putative YP_962367.1 PFAM: Curli production assembly/transport component CsgG; KEGG: shm:Shewmr7_3152 curli production assembly/transport component CsgG YP_962368.1 PFAM: regulatory protein, TetR; KEGG: she:Shewmr4_0871 transcriptional regulator, TetR family YP_962369.1 PFAM: aldehyde dehydrogenase; KEGG: shm:Shewmr7_3150 aldehyde dehydrogenase YP_962370.1 KEGG: she:Shewmr4_0873 hypothetical protein YP_962371.1 PFAM: UspA domain protein; KEGG: shm:Shewmr7_3148 UspA domain protein YP_962372.1 KEGG: she:Shewmr4_0876 extracellular solute-binding protein, family 3 YP_962373.1 KEGG: she:Shewmr4_0878 hypothetical protein YP_962374.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: shm:Shewmr7_0989 xanthine/uracil/vitamin C permease YP_962375.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_962376.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_962377.1 KEGG: she:Shewmr4_0954 hypothetical protein YP_962378.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: son:SO1124 conserved hypothetical protein TIGR00011 YP_962379.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: she:Shewmr4_0956 protein of unknown function DUF6, transmembrane YP_962380.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_962381.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_962382.1 KEGG: pfo:Pfl_4766 chemotaxis sensory transducer, PAS/Pac sensor; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_962383.1 KEGG: she:Shewmr4_0835 hypothetical protein YP_962384.1 KEGG: sil:SPO1693 hypothetical protein YP_962386.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_962387.1 PFAM: Phosphoglycerate mutase; KEGG: she:Shewmr4_0839 phosphoglycerate mutase YP_962388.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1033 iron-compound ABC transporter, ATP-binding protein, putative YP_962389.1 PFAM: transport system permease protein; KEGG: she:Shewmr4_0841 transport system permease protein YP_962390.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_962391.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_962392.1 PFAM: cobalbumin biosynthesis enzyme; KEGG: shm:Shewmr7_3178 cobalbumin biosynthesis enzyme YP_962393.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_962394.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_962395.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: son:SO2036 site-specific recombinase, phage integrase family YP_962396.1 PFAM: putative transposase; KEGG: son:SO2212 transposase, IS91 family, putative YP_962398.1 KEGG: shm:Shewmr7_3175 hypothetical protein YP_962399.1 PFAM: periplasmic binding protein; KEGG: son:SO3709 ABC transporter, periplasmic substrate-binding protein, putative YP_962400.1 PFAM: aldehyde dehydrogenase; KEGG: ppu:PP_2488 succinic-semialdehyde dehydrogenase, putative YP_962401.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_962402.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_0998 DEAD/DEAH box helicase domain protein YP_962403.1 PFAM: peptidase M48, Ste24p; KEGG: son:SO1137 hypothetical protein YP_962404.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: she:Shewmr4_0963 peptidylprolyl isomerase, FKBP-type YP_962405.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_962406.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_962407.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_962408.1 PFAM: pseudouridine synthase; KEGG: sfr:Sfri_3001 pseudouridine synthase YP_962409.1 KEGG: son:SO1143 hypothetical protein YP_962410.1 PFAM: chemotaxis sensory transducer; KEGG: son:SO1144 methyl-accepting chemotaxis protein YP_962411.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: son:SO1145 magnesium transporter YP_962412.1 KEGG: son:SO1146 hypothetical protein YP_962413.1 KEGG: son:SO1148 hypothetical protein YP_962414.1 KEGG: plu:plu4649 transposase, IS4 family YP_962415.1 KEGG: she:Shewmr4_0969 endonuclease/exonuclease/phosphatase YP_962416.1 SMART: PUA domain containing protein; KEGG: son:SO1149 hypothetical SAM-dependent methyltransferase YP_962417.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_962418.1 PFAM: protein of unknown function DUF808; KEGG: she:Shewmr4_0975 protein of unknown function DUF808 YP_962419.1 PFAM: 3'-5' exonuclease; KEGG: shm:Shewmr7_1014 3'-5' exonuclease YP_962420.1 KEGG: shm:Shewmr7_1015 hypothetical protein YP_962421.1 PFAM: SEC-C motif domain protein; KEGG: ppr:PBPRA1441 hypothetical protein YP_962422.1 KEGG: shm:Shewmr7_1016 phage integrase family protein YP_962424.1 KEGG: son:SOA0063 ISSod8, transposase YP_962425.1 KEGG: shm:Shewmr7_1043 hypothetical protein YP_962426.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_0979 TonB-dependent siderophore receptor YP_962427.1 PFAM: protein of unknown function DUF1624; KEGG: she:Shewmr4_0980 hypothetical protein YP_962428.1 PFAM: Ferritin, Dps family protein; KEGG: shm:Shewmr7_1046 ferritin, Dps family protein YP_962429.1 KEGG: shm:Shewmr7_1047 hypothetical protein YP_962430.1 TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; FR47 domain protein; KEGG: son:SO1160 ribosomal-protein-alanine acetyltransferase YP_962431.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_962432.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_962433.1 PFAM: protein of unknown function DUF493; KEGG: shm:Shewmr7_1051 protein of unknown function DUF493 YP_962434.1 PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: son:SO1164 D-alanyl-D-alanine carboxypeptidase YP_962435.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; Sporulation domain protein; KEGG: she:Shewmr4_0988 rare lipoprotein A YP_962436.1 TIGRFAM: lytic murein transglycosylase B; KEGG: shm:Shewmr7_1054 lytic murein transglycosylase B YP_962437.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: shm:Shewmr7_1055 rod shape-determining protein RodA YP_962438.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: shm:Shewmr7_1056 peptidoglycan glycosyltransferase YP_962439.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_962440.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: shm:Shewmr7_1058 iojap-like protein YP_962441.1 KEGG: shm:Shewmr7_1059 nicotinate (nicotinamide) nucleotide adenylyltransferase; TIGRFAM: cytidyltransferase-related domain; nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase YP_962442.1 KEGG: son:SO1172 DNA polymerase III delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta YP_962443.1 PFAM: Rare lipoprotein B; KEGG: shm:Shewmr7_1061 rare lipoprotein B YP_962444.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_962445.1 PFAM: protein of unknown function DUF1451; KEGG: shm:Shewmr7_1063 protein of unknown function DUF1451 YP_962446.1 KEGG: sde:Sde_2848 histidine kinase YP_962447.1 KEGG: shm:Shewmr7_1064 methylation site containing protein YP_962448.1 KEGG: son:SO1176 hypothetical protein YP_962449.1 Transfers the fatty acyl group on membrane lipoproteins YP_962450.1 PFAM: CBS domain containing protein; transporter-associated region; KEGG: shm:Shewmr7_1066 CBS domain containing protein YP_962451.1 PFAM: protein of unknown function UPF0054; KEGG: she:Shewmr4_1002 protein of unknown function UPF0054 YP_962452.1 PFAM: PhoH family protein; KEGG: she:Shewmr4_1003 PhoH family protein YP_962453.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_962454.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase, FAD-binding; KEGG: shm:Shewmr7_1071 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family YP_962455.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_962456.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_962457.1 KEGG: son:SO1187 hypothetical protein YP_962458.1 PFAM: PepSY-associated TM helix domain protein; KEGG: shm:Shewmr7_1075 hypothetical protein YP_962459.1 KEGG: shm:Shewmr7_1076 lysozyme YP_962460.1 KEGG: shm:Shewmr7_1077 hypothetical protein YP_962461.1 TIGRFAM: transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: son:SO1191 transcription elongation factor GreA YP_962462.1 KEGG: son:SO1192 hypothetical protein YP_962463.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_962464.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_962465.1 PFAM: protein of unknown function UPF0044; KEGG: shm:Shewmr7_1082 protein of unknown function UPF0044 YP_962466.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_962467.1 KEGG: she:Shewmr4_1019 ATP-dependent metalloprotease FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_962468.1 KEGG: shm:Shewmr7_1085 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase, DHPS YP_962469.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_962470.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_962471.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: son:SO1201 preprotein translocase, SecG subunit YP_962472.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_962473.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_962474.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_962475.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_962476.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_962477.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_962478.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: shm:Shewmr7_1095 diguanylate cyclase/phosphodiesterase YP_962479.1 KEGG: son:SO1209 polyribonucleotide nucleotidyltransferase; PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH, type 1, domain protein; SMART: KH domain protein YP_962480.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_962481.1 PFAM: phage integrase family protein; KEGG: eci:UTI89_C5085 integrase-like protein YP_962483.1 KEGG: dar:Daro_2530 hypothetical protein YP_962486.1 PFAM: UMUC domain protein DNA-repair protein; KEGG: stt:t4291 UV protection protein YP_962487.1 PFAM: peptidase S24, S26A and S26B; KEGG: sdy:SDY_1220 UmuD YP_962488.1 PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: rfe:RF_p34 DNA polymerase III subunit epsilon YP_962490.1 KEGG: shm:Shewmr7_1781 hypothetical protein YP_962491.1 PFAM: N-6 DNA methylase; KEGG: shm:Shewmr7_1782 N-6 DNA methylase YP_962492.1 KEGG: hit:NTHI0192 putative type I site-specific restriction-modification system, S subunit YP_962493.1 KEGG: shm:Shewmr7_1784 hypothetical protein YP_962494.1 PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_1787 type III restriction enzyme, res subunit YP_962495.1 KEGG: shm:Shewmr7_1788 ATP-binding region, ATPase-like protein YP_962496.1 KEGG: shm:Shewmr7_1789 hypothetical protein YP_962497.1 KEGG: shm:Shewmr7_1790 hypothetical protein YP_962498.1 PFAM: membrane-bound metal-dependent hydrolase; KEGG: shm:Shewmr7_1791 membrane-bound metal-dependent hydrolase YP_962499.1 KEGG: shm:Shewmr7_1792 hypothetical protein YP_962500.1 KEGG: shm:Shewmr7_1793 hypothetical protein YP_962501.1 KEGG: shm:Shewmr7_1794 hypothetical protein YP_962502.1 PFAM: Relaxase; SMART: metal-dependent phosphohydrolase, HD region; KEGG: dar:Daro_2306 relaxase YP_962503.1 KEGG: rfr:Rfer_4266 hypothetical protein YP_962509.1 KEGG: eba:p1B162 sex pilus assembly protein YP_962510.1 KEGG: sty:HCM1.71 putative periplasmic protein YP_962511.1 PFAM: TraB pilus assembly family protein; KEGG: eba:p1B160 sex pilus assembly protein YP_962512.1 KEGG: eba:p1B157 pilus assembly protein YP_962514.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper ion binding protein; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: xcv:XCV2336 copper-translocating P-type ATPase YP_962515.1 TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; KEGG: xcv:XCV2335 transcriptional regulator, MerR family YP_962516.1 PFAM: IstB domain protein ATP-binding protein; IstB ATP binding N-terminal domain protein; SMART: AAA ATPase; KEGG: hch:HCH_06235 IstB helper protein, IS21 family YP_962517.1 PFAM: Integrase, catalytic region; KEGG: hch:HCH_06236 transposase, IS21 family YP_962518.1 KEGG: bxe:Bxe_A4439 heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase YP_962519.1 PFAM: Integrase, catalytic region; KEGG: ecc:c5144 hypothetical protein YP_962520.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: gvi:gll4066 putative transposase YP_962521.1 PFAM: Integrase, catalytic region; KEGG: vpa:VP1787 putative transposase YP_962522.1 PFAM: transposase IS3/IS911 family protein; KEGG: ssn:SSO_P025 IS3 ORF1 YP_962523.1 TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; KEGG: xcv:XCV2335 transcriptional regulator, MerR family YP_962524.1 PFAM: regulatory protein, ArsR; KEGG: xcv:XCV2337 transcriptional regulator, ArsR family YP_962525.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: xcv:XCV2338 cobalt-zinc-cadmium resistance protein YP_962526.1 PFAM: regulatory protein, ArsR; KEGG: xcv:XCV2337 transcriptional regulator, ArsR family YP_962527.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: pcr:Pcryo_1347 heavy metal translocating P-type ATPase YP_962528.1 PFAM: Integrase, catalytic region; KEGG: vpa:VP1787 putative transposase YP_962529.1 PFAM: transposase IS3/IS911 family protein; KEGG: ssn:SSO_P025 IS3 ORF1 YP_962530.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sec:SC0394 putative cation efflux pump YP_962531.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: stm:STM0351 putative cation efflux system protein YP_962532.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: sec:SC0393 outer membrane efflux protein-like protein YP_962533.1 KEGG: rpd:RPD_2310 hydrophobe/amphiphile efflux-1 HAE1 YP_962534.1 KEGG: stm:STM0355 putative Copper chaperone YP_962535.1 KEGG: ppr:PBPRA1824 hypothetical protein YP_962536.1 KEGG: psp:PSPPH_1359 thiol:disulfide interchange protein DsbC YP_962537.1 KEGG: eba:p1B154 sex pilus assembly protein YP_962539.1 KEGG: sty:HCM1.98 putative pilin maturation protein YP_962540.1 KEGG: sty:HCM1.99 plasmid transfer protein YP_962541.1 PFAM: TraU family protein; KEGG: sty:HCM1.100 plasmid transfer protein YP_962542.1 PFAM: Mating pair stabilisation TraN; KEGG: sty:HCM1.101 plasmid transfer protein YP_962544.1 KEGG: bca:BCE_1701 hypothetical protein YP_962546.1 PFAM: Endonuclease I; KEGG: sbo:SBO_3045 DNA-specific endonuclease I YP_962549.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: abo:ABO_0430 single-stranded DNA-binding protein YP_962550.1 TIGRFAM: phage recombination protein Bet; PFAM: RecT protein; KEGG: ecp:ECP_1141 bacteriophage recombination protein YP_962551.1 KEGG: eba:p1B105 hypothetical protein YP_962552.1 PFAM: ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: dvu:DVU2037 CobS protein, putative YP_962554.1 KEGG: lip:LI0186 hypothetical protein YP_962556.1 PFAM: von Willebrand factor, type A; VWA containing CoxE family protein; KEGG: gsu:GSU2161 hypothetical protein YP_962557.1 PFAM: DNA repair protein RadC; KEGG: vvy:VV2251 DNA repair protein YP_962559.1 PFAM: Phage P4 alpha, zinc-binding domain protein; KEGG: dar:Daro_2694 hypothetical protein YP_962561.1 KEGG: sdn:Sden_0608 hypothetical protein YP_962562.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: sde:Sde_1955 cation efflux system protein YP_962563.1 PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: sde:Sde_1956 hypothetical protein YP_962564.1 PFAM: outer membrane efflux protein; KEGG: sde:Sde_1958 aconitate hydratase 1 YP_962566.1 KEGG: abo:ABO_1368 cation efflux system permease, putative YP_962567.1 TIGRFAM: Cd(II)/Pb(II)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; KEGG: sde:Sde_1961 putative transcriptional regulator, MerR family YP_962568.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: tcx:Tcr_1429 cation diffusion facilitator family transporter YP_962569.1 PFAM: protein of unknown function UPF0060; KEGG: abo:ABO_1373 hypothetical protein YP_962570.1 KEGG: eba:p1B150 sex pilus assembly protein YP_962571.1 PFAM: TraH family protein; KEGG: stm:PSLT100 pilus assembly protein YP_962572.1 PFAM: TraG domain protein; KEGG: eba:p1B148 sex pilus assembly YP_962574.1 KEGG: rfr:Rfer_3701 flagellar regulon master regulator subunit FlhC YP_962576.1 PFAM: Lytic transglycosylase, catalytic; KEGG: net:Neut_0100 lytic transglycosylase, catalytic YP_962577.1 KEGG: tcx:Tcr_0792 hypothetical protein YP_962579.1 KEGG: par:Psyc_0471 hypothetical protein YP_962580.1 PFAM: helix-turn-helix domain protein; peptidase S24, S26A and S26B; bacteriophage CI repressor; KEGG: sfv:SFV_0270 putative prophage repressor CI YP_962581.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_962582.1 KEGG: sfr:Sfri_0998 hypothetical protein YP_962583.1 PFAM: TatD-related deoxyribonuclease; KEGG: son:SO1213 hydrolase, TatD family YP_962584.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: shm:Shewmr7_1100 nucleoside transporter YP_962585.1 PFAM: nucleoside-specific channel-forming protein, Tsx; KEGG: shm:Shewmr7_1101 nucleoside-specific channel-forming protein, Tsx YP_962586.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_962587.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_962588.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_962589.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_962590.1 KEGG: son:SO1222 membrane protein YP_962591.1 KEGG: she:Shewmr4_1042 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase YP_962592.1 KEGG: shm:Shewmr7_1108 alpha/beta hydrolase fold YP_962593.1 PFAM: type IV pilus assembly PilZ; KEGG: she:Shewmr4_1044 type IV pilus assembly PilZ YP_962594.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_962595.1 PFAM: type IV pilus assembly PilZ; KEGG: shm:Shewmr7_1111 type IV pilus assembly PilZ YP_962596.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: son:SO1236 xanthine/uracil permease family protein YP_962597.1 PFAM: CBS domain containing protein; KEGG: shm:Shewmr7_1120 CBS domain containing protein YP_962598.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: shm:Shewmr7_1121 phospholipid/glycerol acyltransferase YP_962599.1 PFAM: metallophosphoesterase; KEGG: son:SO1239 hypothetical protein YP_962600.1 KEGG: ilo:IL2089 predicted ATPase, possibly involved in inorganic ion transport YP_962601.1 PFAM: nucleoside recognition domain protein; KEGG: shm:Shewmr7_1129 nucleoside recognition domain protein YP_962602.1 KEGG: she:Shewmr4_1059 hypothetical protein YP_962603.1 PFAM: peptidase U32; KEGG: son:SO1248 hypothetical peptidase YP_962604.1 PFAM: peptidase U32; KEGG: she:Shewmr4_1061 peptidase U32 YP_962605.1 KEGG: shm:Shewmr7_1134 sterol-binding domain protein YP_962606.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_1135 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_962607.1 PFAM: peptidase U32; KEGG: son:SO1252 peptidase, U32 family YP_962608.1 PFAM: HDOD; KEGG: shm:Shewmr7_1137 putative signal transduction protein YP_962609.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: she:Shewmr4_1066 diguanylate cyclase/phosphodiesterase YP_962610.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_1139 thioesterase superfamily protein YP_962611.1 PFAM: response regulator receiver; CheW domain protein; KEGG: vpa:VPA0746 chemotaxis protein CheV YP_962612.1 PFAM: adenylosuccinate synthetase; KEGG: shm:Shewmr7_1140 adenylosuccinate synthase YP_962613.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_1141 transcriptional regulator, LysR family YP_962614.1 KEGG: she:Shewmr4_1070 extracellular solute-binding protein, family 3 YP_962615.1 PFAM: OsmC family protein; KEGG: shm:Shewmr7_1143 OsmC family protein YP_962616.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_1144 transcriptional regulator, TetR family YP_962617.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_1073 efflux transporter, RND family, MFP subunit YP_962618.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_1074 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family YP_962619.1 PFAM: protein of unknown function DUF88; KEGG: sdn:Sden_0372 protein of unknown function DUF88 YP_962620.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: son:SO3488 transcriptional regulator, AraC/XylS family YP_962621.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_1082 drug resistance transporter, Bcr/CflA subfamily YP_962622.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_1149 acriflavin resistance protein YP_962623.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_1150 efflux transporter, RND family, MFP subunit YP_962624.1 KEGG: pfl:PFL_0312 hypothetical protein YP_962625.1 KEGG: shm:Shewmr7_1155 putative protein-disulfide isomerase YP_962626.1 PFAM: beta-lactamase domain protein; KEGG: son:SO3474 metallo-beta-lactamase family protein YP_962627.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_1157 transcriptional regulator, LysR family YP_962628.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_962629.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_962630.1 PFAM: ATP-cone domain protein; KEGG: shm:Shewmr7_1161 ribonucleotide reductase regulator NrdR-like protein YP_962631.1 KEGG: son:SO3469 riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase, zinc-binding; bifunctional deaminase-reductase domain protein YP_962632.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_962633.1 PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; KEGG: shm:Shewmr7_1164 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_962634.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_962635.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_962636.1 KEGG: she:Shewmr4_1101 thiamine-monophosphate kinase; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein domain protein YP_962637.1 PFAM: phosphatidylglycerophosphatase A; KEGG: shm:Shewmr7_1168 phosphatidylglycerophosphatase YP_962638.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: she:Shewmr4_1104 DNA repair protein RecN YP_962639.1 PFAM: Auxin Efflux Carrier; KEGG: shm:Shewmr7_1171 auxin efflux carrier YP_962640.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO3460 transcriptional regulator, LysR family YP_962641.1 PFAM: protein of unknown function DUF416; KEGG: she:Shewmr4_1108 protein of unknown function DUF416 YP_962642.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_962643.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_962644.1 KEGG: son:SO3455 GTP pyrophosphokinase; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; RelA/SpoT domain protein YP_962645.1 KEGG: eba:ebA5435 conserved hypothetical protein, probable DNA/RNA helicase YP_962646.1 KEGG: cps:CPS_1152 hypothetical protein YP_962647.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_962648.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_962649.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis YP_962650.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_962651.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_962652.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_962653.1 PFAM: Septum formation initiator; KEGG: shm:Shewmr7_1187 septum formation initiator YP_962654.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_962655.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_962656.1 PFAM: tRNA pseudouridine synthase D, TruD; KEGG: shm:Shewmr7_1190 pseudouridylate synthase YP_962657.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_962658.1 KEGG: son:SO3434 protein-L-isoaspartate O-methyltransferase; TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_962659.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; KEGG: shm:Shewmr7_1193 peptidase M23B YP_962660.1 TIGRFAM: RNA polymerase sigma factor RpoS; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70 region 1.2; KEGG: son:SO3432 RNA polymerase sigma-38 factor YP_962661.1 This protein performs the mismatch recognition step during the DNA repair process YP_962662.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_962663.1 PFAM: regulatory protein RecX; KEGG: shm:Shewmr7_1197 regulatory protein RecX YP_962664.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_962665.1 KEGG: shm:Shewmr7_1199 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase YP_962666.1 affects carbohydrate metabolism; has regulatory role in many processes YP_962667.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_962668.1 PFAM: DNA polymerase III chi subunit, HolC; KEGG: she:Shewmr4_1131 DNA polymerase III chi subunit, HolC YP_962669.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: shm:Shewmr7_1203 sigma 54 modulation protein/ribosomal protein S30EA YP_962670.1 PFAM: cytochrome B561; KEGG: she:Shewmr4_1133 cytochrome b561 YP_962671.1 PFAM: cytochrome c, class II; KEGG: shm:Shewmr7_1205 cytochrome c, class II YP_962672.1 TIGRFAM: trp operon repressor; PFAM: Trp repressor; KEGG: son:SO3419 trp operon repressor YP_962673.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO3417 peptidyl-prolyl cis-trans isomerase SlyD YP_962674.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_962675.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_962676.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_962677.1 SMART: extracellular solute-binding protein, family 3; KEGG: son:SO3412 extracellular solute-binding proteins, family 3 protein YP_962678.1 PFAM: peptidase S41; WD40 domain protein beta Propeller; SMART: PDZ/DHR/GLGF domain protein; KEGG: son:SO3411 protease, putative YP_962679.1 PFAM: OsmC family protein; KEGG: son:SO3409 OsmC/Ohr family protein YP_962680.1 KEGG: she:Shewmr4_1146 hypothetical protein YP_962681.1 PFAM: PepSY-associated TM helix domain protein; KEGG: son:SO3407 hypothetical protein YP_962682.1 KEGG: shm:Shewmr7_1219 hypothetical protein YP_962683.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; KEGG: she:Shewmr4_1149 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor YP_962684.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: shm:Shewmr7_1221 sigma 54 modulation protein/ribosomal protein S30EA YP_962685.1 PFAM: protein of unknown function DUF28; KEGG: son:SO3401 hypothetical protein YP_962686.1 PFAM: chemotaxis sensory transducer; KEGG: shm:Shewmr7_1226 methyl-accepting chemotaxis sensory transducer YP_962687.1 KEGG: shm:Shewmr7_1227 hypothetical protein YP_962688.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_1228 transcriptional regulator, TetR family YP_962689.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: she:Shewmr4_1158 NADH:flavin oxidoreductase/NADH oxidase YP_962690.1 KEGG: shm:Shewmr7_1230 peptidase S16, lon domain protein YP_962691.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO3388 ATP-dependent RNA helicase, DEAD box family YP_962692.1 KEGG: she:Shewmr4_1162 hypothetical protein YP_962693.1 PFAM: protein of unknown function DUF523; Protein of unknown function DUF1722; KEGG: shm:Shewmr7_1234 protein of unknown function DUF1722 YP_962694.1 PFAM: regulatory protein, MerR; KEGG: son:SO3385 transcriptional regulator, MerR family YP_962695.1 PFAM: DNA photolyase, FAD-binding; DNA photolyase domain protein; KEGG: she:Shewmr4_1165 deoxyribodipyrimidine photo-lyase YP_962696.1 KEGG: shm:Shewmr7_1237 transcriptional regulator-related protein YP_962697.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: she:Shewmr4_1167 short-chain dehydrogenase/reductase SDR YP_962698.1 PFAM: amine oxidase; KEGG: shm:Shewmr7_1239 amine oxidase YP_962699.1 PFAM: protein of unknown function DUF1365; KEGG: she:Shewmr4_1169 protein of unknown function DUF1365 YP_962700.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_1241 cyclopropane-fatty-acyl-phospholipid synthase YP_962701.1 KEGG: son:SO3378 hypothetical protein YP_962702.1 KEGG: son:SO3377 hypothetical protein YP_962703.1 KEGG: shm:Shewmr7_1244 hypothetical protein YP_962704.1 KEGG: shm:Shewmr7_1246 hypothetical protein YP_962705.1 PFAM: cytochrome B561; KEGG: she:Shewmr4_1177 cytochrome b561 YP_962706.1 PFAM: YceI family protein; KEGG: son:SO3370 hypothetical protein YP_962707.1 PFAM: Fe(II) trafficking protein YggX; KEGG: son:SO3369 hypothetical protein YP_962708.1 TIGRFAM: A/G-specific adenine glycosylase; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: shm:Shewmr7_1251 A/G-specific adenine glycosylase YP_962709.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_962710.1 PFAM: protein of unknown function DUF469; KEGG: son:SO3366 hypothetical protein YP_962711.1 catalyzes the formation of glutamate from glutamine YP_962712.1 KEGG: shm:Shewmr7_1255 hypothetical protein YP_962713.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_1256 transcriptional regulator, LysR family YP_962714.1 PFAM: protein of unknown function DUF885; KEGG: she:Shewmr4_1186 protein of unknown function DUF885 YP_962715.1 KEGG: she:Shewmr4_1187 putative oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB YP_962716.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_962717.1 KEGG: shm:Shewmr7_1260 hypothetical protein YP_962718.1 PFAM: protein of unknown function DUF167; KEGG: son:SO3356 hypothetical protein YP_962719.1 PFAM: protein of unknown function YGGT; KEGG: she:Shewmr4_1191 protein of unknown function YGGT YP_962720.1 KEGG: son:SO3354 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_962721.1 PFAM: alanine racemase domain protein; KEGG: shm:Shewmr7_1264 protein of unknown function UPF0001 YP_962722.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: son:SO3351 twitching motility protein PilT YP_962723.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: shm:Shewmr7_1266 twitching motility protein YP_962724.1 PFAM: glutathione peroxidase; KEGG: shm:Shewmr7_1267 glutathione peroxidase YP_962725.1 PFAM: ferrochelatase; KEGG: shm:Shewmr7_1268 ferrochelatase YP_962726.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_962727.1 PFAM: protein of unknown function DUF179; KEGG: son:SO3346 putative transcriptional regulator YP_962728.1 involved in start site selection during the initiation of translation YP_962729.1 KEGG: shm:Shewmr7_1272 hypothetical protein YP_962730.1 KEGG: son:SO3343 hypothetical protein YP_962731.1 PFAM: protein of unknown function UPF0126; KEGG: shm:Shewmr7_1274 protein of unknown function UPF0126 YP_962732.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shm:Shewmr7_1275 redoxin domain protein YP_962733.1 PFAM: MscS Mechanosensitive ion channel; KEGG: shm:Shewmr7_1276 MscS mechanosensitive ion channel YP_962734.1 PFAM: OmpA/MotB domain protein; KEGG: son:SO3339 OmpA family protein YP_962735.1 PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: she:Shewmr4_1207 threonine aldolase YP_962736.1 PFAM: protein of unknown function DUF980; KEGG: she:Shewmr4_1210 protein of unknown function DUF980 YP_962737.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO3334 GGDEF family protein YP_962738.1 PFAM: extracellular solute-binding protein, family 1; KEGG: she:Shewmr4_1212 extracellular solute-binding protein, family 1 YP_962739.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO3328 acetyltransferase, GNAT family YP_962740.1 KEGG: she:Shewmr4_1216 hypothetical protein YP_962741.1 KEGG: shm:Shewmr7_1288 NrfJ-related protein YP_962742.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_1289 GCN5-related N-acetyltransferase YP_962743.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_1219 GCN5-related N-acetyltransferase YP_962744.1 PFAM: Pirin domain protein domain protein; Cupin 2, conserved barrel domain protein; KEGG: shm:Shewmr7_1291 pirin domain protein domain protein YP_962745.1 PFAM: DoxX family protein; KEGG: shm:Shewmr7_1292 DoxX family protein YP_962746.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_1222 transcriptional regulator, LysR family YP_962747.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: shm:Shewmr7_1294 metallophosphoesterase YP_962748.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; KEGG: shm:Shewmr7_1295 protein of unknown function DUF21 YP_962749.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_962750.1 KEGG: she:Shewmr4_1226 type IV pilus biogenesis/stability protein PilW; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_962751.1 KEGG: she:Shewmr4_1227 hypothetical protein YP_962752.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_962753.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_962754.1 KEGG: shm:Shewmr7_1301 hypothetical protein YP_962755.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_962756.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_962757.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_962758.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_962759.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_962760.1 PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: she:Shewmr4_1236 CMP/dCMP deaminase, zinc-binding YP_962761.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_962762.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_962763.1 PFAM: cytochrome bd ubiquinol oxidase, subunit I; KEGG: shm:Shewmr7_1310 cytochrome bd ubiquinol oxidase, subunit I YP_962764.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II; KEGG: son:SO3285 cytochrome bd-I oxidase subunit II YP_962765.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: shm:Shewmr7_1312 cyd operon protein YbgT YP_962766.1 KEGG: she:Shewmr4_1960 hypothetical protein YP_962767.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_1243 methyl-accepting chemotaxis sensory transducer YP_962768.1 PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_1245 acriflavin resistance protein YP_962769.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO3278 hypothetical protein YP_962770.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_1317 transcriptional regulator, TetR family YP_962771.1 KEGG: she:Shewmr4_1248 hypothetical protein YP_962772.1 KEGG: shm:Shewmr7_1319 hypothetical protein YP_962773.1 KEGG: shm:Shewmr7_1320 hypothetical protein YP_962774.1 PFAM: protein of unknown function DUF115; KEGG: son:SO3273 hypothetical protein YP_962775.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: son:SO3271 polysaccharide biosynthesis protein YP_962776.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: son:SO3270 polysaccharide biosynthesis protein YP_962777.1 PFAM: acylneuraminate cytidylyltransferase; KEGG: par:Psyc_0656 putative acylneuraminate cytidylyltransferase YP_962778.1 KEGG: pfl:PFL_1624 FlaR protein (FlaR) YP_962779.1 PFAM: N-acetylneuraminic acid synthase, N-terminal domain; SAF domain; KEGG: pfl:PFL_1625 NeuB family protein YP_962780.1 KEGG: sus:Acid_6945 GCN5-related N-acetyltransferase YP_962781.1 KEGG: sus:Acid_1361 acyl carrier protein YP_962782.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: sus:Acid_1362 short-chain dehydrogenase/reductase SDR YP_962783.1 PFAM: AMP-dependent synthetase and ligase; KEGG: rha:RHA1_ro07030 possible acyl-CoA synthetase YP_962784.1 PFAM: acyl-protein synthetase, LuxE; KEGG: sus:Acid_1364 acyl-protein synthetase, LuxE YP_962785.1 KEGG: sus:Acid_1365 hypothetical protein YP_962786.1 KEGG: bfr:BF2579 putative cholinephosphotransferase YP_962787.1 PFAM: Methyltransferase type 12; KEGG: pau:PA14_50330 hypothetical protein YP_962788.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_962789.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_962790.1 KEGG: plu:plu4649 transposase, IS4 family YP_962791.1 KEGG: pau:PA14_50320 hypothetical protein YP_962792.1 KEGG: pau:PA14_50310 possible sugar nucleotidyltransferase YP_962793.1 KEGG: son:SO3260 hypothetical protein YP_962794.1 KEGG: son:SO3259 hypothetical protein YP_962795.1 KEGG: she:Shewmr4_1251 hypothetical protein YP_962796.1 KEGG: shm:Shewmr7_1322 hypothetical protein YP_962797.1 PFAM: protein of unknown function DUF400; KEGG: son:SO3256 hypothetical protein YP_962798.1 PFAM: FlgN family protein; KEGG: shm:Shewmr7_1324 FlgN family protein YP_962799.1 PFAM: Anti-sigma-28 factor, FlgM family protein; KEGG: shm:Shewmr7_1325 anti-sigma-28 factor, FlgM YP_962800.1 required for the assembly of the flagellar basal body P-ring YP_962801.1 PFAM: response regulator receiver; CheW domain protein; KEGG: son:SO3252 chemotaxis protein CheV YP_962802.1 PFAM: MCP methyltransferase, CheR-type; Methyltransferase type 12; KEGG: son:SO3251 chemotaxis protein methyltransferase CheR YP_962803.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod YP_962804.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_962805.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_962806.1 the hook connects flagellar basal body to the flagellar filament YP_962807.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_962808.1 makes up the distal portion of the flagellar basal body rod YP_962809.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod YP_962810.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_962811.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_962812.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: shm:Shewmr7_1338 flagellar hook-associated protein FlgK YP_962813.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes. YP_962814.1 PFAM: flagellin domain protein; KEGG: sdn:Sden_1314 flagellin-like protein YP_962815.1 PFAM: flagellin domain protein; KEGG: sdn:Sden_1315 flagellin-like protein YP_962816.1 PFAM: flagellar protein FlaG protein; KEGG: son:SO3236 flagellin FlaG YP_962817.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; KEGG: son:SO3235 flagellar hook-associated protein FliD YP_962818.1 KEGG: son:SO3234 hypothetical protein YP_962819.1 flagellin specific chaperone YP_962820.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; flagellar regulatory FleQ domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_1345 sigma54 specific transcriptional regulator, fis family YP_962821.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; SMART: PAS domain containing protein; KEGG: son:SO3231 flagellar regulatory protein B YP_962822.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: she:Shewmr4_1280 two component, sigma54 specific, transcriptional regulator, fis family YP_962823.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: she:Shewmr4_1281 flagellar hook-basal body complex subunit FliE YP_962824.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_962825.1 One of three proteins involved in switching the direction of the flagellar rotation YP_962826.1 binds to and inhibits the function of flagella specific ATPase FliI YP_962827.1 involved in type III protein export during flagellum assembly YP_962828.1 TIGRFAM: flagellar export protein FliJ; KEGG: shm:Shewmr7_1353 flagellar export protein FliJ YP_962829.1 PFAM: flagellar hook-length control protein; KEGG: son:SO3223 flagellar hook-length control protein FliK YP_962830.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_962831.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_962832.1 One of three proteins involved in switching the direction of the flagellar rotation YP_962833.1 PFAM: flagellar biosynthesis protein, FliO; KEGG: she:Shewmr4_1291 flagellar biosynthesis protein, FliO YP_962834.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_962835.1 TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ, family 3; KEGG: son:SO3217 flagellar biosynthetic protein FliQ YP_962836.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_962837.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_962838.1 membrane protein involved in the flagellar export apparatus YP_962839.1 positive regulator of class III flagellar genes YP_962840.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: shm:Shewmr7_1365 cobyrinic acid a,c-diamide synthase YP_962841.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_962842.1 PFAM: response regulator receiver; KEGG: sfr:Sfri_1200 response regulator receiver protein YP_962843.1 PFAM: Chemotaxis phosphatase, CheZ; KEGG: shm:Shewmr7_1368 chemotaxis phosphatase, CheZ YP_962844.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: she:Shewmr4_1302 CheA signal transduction histidine kinases YP_962845.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_962846.1 KEGG: she:Shewmr4_1304 hypothetical protein YP_962847.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: son:SO3204 ParA family protein YP_962848.1 PFAM: CheW domain protein; KEGG: she:Shewmr4_1306 CheW protein YP_962849.1 PFAM: CheW domain protein; KEGG: shm:Shewmr7_1374 CheW protein YP_962850.1 KEGG: shm:Shewmr7_1375 hypothetical protein YP_962851.1 KEGG: shm:Shewmr7_1376 FlhB domain protein YP_962852.1 KEGG: she:Shewmr4_1310 hypothetical protein YP_962853.1 PFAM: VacJ family lipoprotein; KEGG: shm:Shewmr7_1378 VacJ family lipoprotein YP_962854.1 PFAM: response regulator receiver; KEGG: shm:Shewmr7_1379 response regulator receiver protein YP_962855.1 TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor, type I/II extracellular region; major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_1380 amino acid/peptide transporter YP_962856.1 KEGG: son:SO3194 transcriptional activator rfaH, putative; TIGRFAM: transcriptional activator RfaH; PFAM: transcription antitermination protein NusG; SMART: NGN domain protein YP_962857.1 PFAM: polysaccharide export protein; KEGG: she:Shewmr4_1315 polysaccharide export protein YP_962858.1 PFAM: lipopolysaccharide biosynthesis; KEGG: shm:Shewmr7_1384 lipopolysaccharide biosynthesis YP_962859.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose YP_962860.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sfr:Sfri_2829 glucose-1-phosphate thymidylyltransferase YP_962861.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: sdn:Sden_2661 dTDP-4-dehydrorhamnose reductase YP_962862.1 KEGG: sbo:SBO_0865 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_962863.1 PFAM: polysaccharide biosynthesis protein; KEGG: she:Shewmr4_1320 polysaccharide biosynthesis protein YP_962864.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: she:Shewmr4_1321 DegT/DnrJ/EryC1/StrS aminotransferase YP_962865.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: she:Shewmr4_1322 acetyltransferase RfbO, CysE/LacA/LpxA/NodL family YP_962866.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: pen:PSEEN4077 chloramphenicol acetyltransferase YP_962867.1 PFAM: glycosyl transferase, family 2; KEGG: plt:Plut_0769 glycosyltransferase involved in cell wall biogenesis-like YP_962868.1 PFAM: transposase, IS4 family protein; KEGG: sak:SAK_2050 IS10R, transposase YP_962869.1 KEGG: shm:Shewmr7_1399 dTDP-glucose 4,6-dehydratase YP_962870.1 PFAM: Excinuclease ABC, C subunit domain protein; KEGG: nme:NMB0047 putative endonuclease YP_962871.1 KEGG: she:Shewmr4_1339 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_962872.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase, family 4; KEGG: shm:Shewmr7_1396 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase YP_962874.1 PFAM: copper resistance lipoprotein NlpE; KEGG: son:SO3163 lipoprotein YP_962875.1 PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein; KEGG: son:SO3162 sensor histidine kinase YP_962876.1 PFAM: Excinuclease ABC, C subunit domain protein; KEGG: nme:NMB0047 putative endonuclease YP_962877.1 PFAM: protein of unknown function DUF940, membrane lipoprotein putative; KEGG: shm:Shewmr7_1405 protein of unknown function DUF940, membrane lipoprotein putative YP_962878.1 PFAM: protein of unknown function DUF1017; KEGG: shm:Shewmr7_1406 protein of unknown function DUF1017 YP_962879.1 KEGG: she:Shewmr4_1342 lipoprotein, putative YP_962880.1 KEGG: she:Shewmr4_1343 hypothetical protein YP_962881.1 PFAM: Patatin; KEGG: shm:Shewmr7_1409 patatin YP_962882.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_962883.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: shm:Shewmr7_1411 transferase hexapeptide repeat containing protein YP_962884.1 PFAM: protein of unknown function UPF0066; KEGG: she:Shewmr4_1347 protein of unknown function UPF0066 YP_962885.1 KEGG: shm:Shewmr7_1413 lipoprotein, putative YP_962886.1 KEGG: son:SO3149 hypothetical protein YP_962887.1 PFAM: amidohydrolase; KEGG: shm:Shewmr7_1415 amidohydrolase YP_962888.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: shm:Shewmr7_1416 histone family protein nucleoid-structuring protein H-NS YP_962889.1 PFAM: electron transfer flavoprotein beta-subunit; KEGG: shm:Shewmr7_1417 electron transfer flavoprotein beta-subunit YP_962890.1 PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit; KEGG: shm:Shewmr7_1418 electron transfer flavoprotein, alpha subunit YP_962891.1 PFAM: Na+/H+ antiporter NhaC; KEGG: shm:Shewmr7_1419 Na+/H+ antiporter NhaC YP_962892.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: shm:Shewmr7_1420 peptidyl-dipeptidase DCP YP_962893.1 KEGG: she:Shewmr4_1356 hypothetical protein YP_962894.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_962895.1 KEGG: she:Shewmr4_1358 hypothetical protein YP_962896.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_1424 two component, sigma54 specific, transcriptional regulator, fis family YP_962897.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_1360 periplasmic sensor signal transduction histidine kinase YP_962898.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: shm:Shewmr7_1426 TRAP dicarboxylate transporter, DctM subunit YP_962899.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: she:Shewmr4_1362 tripartite ATP-independent periplasmic transporter, DctQ component YP_962900.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: shm:Shewmr7_1428 TRAP dicarboxylate transporter, DctP subunit YP_962901.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_962902.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: she:Shewmr4_1366 ABC transporter related YP_962903.1 PFAM: helix-turn-helix- domain containing protein, AraC type; HhH-GPD family protein; Ada, metal-binding domain protein; AlkA domain protein; KEGG: son:SO3127 Ada regulatory protein, putative YP_962904.1 KEGG: shm:Shewmr7_1433 methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase YP_962905.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_1434 DEAD/DEAH box helicase domain protein YP_962906.1 PFAM: Dual specificity protein phosphatase; KEGG: son:SO3124 tyrosine-specific protein phosphatase, putative YP_962907.1 PFAM: response regulator receiver; CheW domain protein; KEGG: shm:Shewmr7_1437 response regulator receiver modulated CheW protein YP_962908.1 involved in the import of serine and threonine coupled with the import of sodium YP_962909.1 PFAM: NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30; KEGG: son:SO3121 hypothetical protein YP_962910.1 PFAM: oxidoreductase domain protein; KEGG: shm:Shewmr7_1440 twin-arginine translocation pathway signal YP_962911.1 KEGG: son:SO3119 hypothetical protein YP_962912.1 PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_1442 pseudouridylate synthase YP_962913.1 PFAM: protein of unknown function DUF479; KEGG: shm:Shewmr7_1444 protein of unknown function DUF479 YP_962914.1 KEGG: son:SO3115 hypothetical protein YP_962915.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_962916.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_962917.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_962918.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_962919.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_962920.1 KEGG: shm:Shewmr7_1451 hypothetical protein YP_962921.1 TIGRFAM: siroheme synthase; KEGG: son:SO3108 precorrin-2 oxidase / ferrochelatase YP_962922.1 PFAM: YaeQ family protein; KEGG: son:SO3107 hypothetical protein YP_962923.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; Proprotein convertase, P; protease-associated PA domain protein; peptidase domain protein; proteinase inhibitor I9, subtilisin propeptide; KEGG: shm:Shewmr7_1455 peptidase S8 and S53, subtilisin, kexin, sedolisin YP_962924.1 PFAM: Rhodanese domain protein; KEGG: son:SO3105 phage shock protein E YP_962925.1 KEGG: shm:Shewmr7_1457 hypothetical protein YP_962926.1 PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_1393 acriflavin resistance protein YP_962927.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_1394 efflux transporter, RND family, MFP subunit YP_962928.1 PFAM: protein of unknown function DUF541; KEGG: shm:Shewmr7_1460 protein of unknown function DUF541 YP_962929.1 KEGG: shm:Shewmr7_1461 hypothetical protein YP_962930.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: son:SO3099 long-chain fatty acid transport protein, putative YP_962931.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: shm:Shewmr7_1463 sodium/proline symporter YP_962932.1 KEGG: she:Shewmr4_1399 hypothetical protein YP_962933.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_962934.1 KEGG: shm:Shewmr7_1466 hypothetical protein YP_962935.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: von Willebrand factor, type A; Tetratricopeptide domain protein; KEGG: she:Shewmr4_1402 tetratricopeptide TPR_2 repeat protein YP_962936.1 PFAM: von Willebrand factor, type A; KEGG: shm:Shewmr7_1468 von Willebrand factor, type A YP_962937.1 KEGG: shm:Shewmr7_1469 hypothetical protein YP_962938.1 PFAM: protein of unknown function DUF58; KEGG: son:SO3091 hypothetical protein YP_962939.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; KEGG: shm:Shewmr7_1471 ATPase associated with various cellular activities, AAA_3 YP_962940.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_962941.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_962942.1 KEGG: son:SO3087 hypothetical protein YP_962943.1 KEGG: she:Shewmr4_1410 hypothetical protein YP_962944.1 KEGG: she:Shewmr4_1411 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; Two component regulator three Y domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_962945.1 PFAM: peptidase M16 domain protein; KEGG: shm:Shewmr7_1477 peptidase M16 domain protein YP_962946.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase; KEGG: she:Shewmr4_1413 phosphohistidine phosphatase, SixA YP_962947.1 PFAM: Smr protein/MutS2; KEGG: son:SO3081 Smr domain protein YP_962948.1 involved in methylation of ribosomal protein L3 YP_962949.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_962950.1 PFAM: nucleoside:H+ symporter; major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_1482 major facilitator superfamily MFS_1 YP_962951.1 PFAM: ATP-NAD/AcoX kinase; KEGG: son:SO3077 hypothetical protein YP_962952.1 KEGG: she:Shewmr4_1419 hypothetical protein YP_962953.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: shm:Shewmr7_1485 tRNA/rRNA methyltransferase (SpoU) YP_962954.1 PFAM: FAD dependent oxidoreductase; KEGG: she:Shewmr4_1421 FAD dependent oxidoreductase YP_962955.1 PFAM: beta-ketoacyl synthase; KEGG: shm:Shewmr7_1487 beta-ketoacyl synthase YP_962956.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: son:SO3071 erythronate-4-phosphate dehydrogenase YP_962957.1 KEGG: shm:Shewmr7_1489 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region YP_962958.1 KEGG: shm:Shewmr7_1490 hypothetical protein YP_962959.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_962960.1 KEGG: she:Shewmr4_1427 FolC bifunctional protein; TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein YP_962961.1 PFAM: Sporulation domain protein; KEGG: shm:Shewmr7_1493 sporulation domain protein YP_962962.1 PFAM: Colicin V production protein; KEGG: son:SO3065 colicin V production protein YP_962963.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_962964.1 decatenates replicating daughter chromosomes YP_962965.1 PFAM: porin, Gram-negative type; KEGG: son:SO3060 outer membrane porin, putative YP_962966.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: son:SO3059 formate hydrogenlyase transcriptional activator, putative YP_962967.1 TIGRFAM: flavocytochrome c; PFAM: monooxygenase, FAD-binding; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO3058 flavocytochrome c flavin subunit, putative YP_962968.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: son:SO3057 Pal/histidase family protein YP_962969.1 KEGG: son:SO3056 tetraheme cytochrome c YP_962970.1 PFAM: alpha/beta hydrolase fold; KEGG: she:Shewmr4_1434 alpha/beta hydrolase fold YP_962971.1 PFAM: beta-lactamase domain protein; KEGG: shm:Shewmr7_1500 beta-lactamase domain protein YP_962972.1 PFAM: protein of unknown function DUF182; KEGG: she:Shewmr4_1437 protein of unknown function DUF182 YP_962973.1 KEGG: she:Shewmr4_1438 hypothetical protein YP_962974.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: shm:Shewmr7_1504 (2Fe-2S)-binding domain protein YP_962975.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: son:SO3048 isoquinoline 1-oxidoreductase, beta subunit, putative YP_962976.1 PFAM: protein of unknown function DUF1097; KEGG: shm:Shewmr7_1506 protein of unknown function DUF1097 YP_962977.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_1442 methyl-accepting chemotaxis sensory transducer YP_962978.1 KEGG: son:SO3045 hypothetical protein YP_962979.1 KEGG: shm:Shewmr7_1510 hypothetical protein YP_962980.1 KEGG: rpe:RPE_3539 hypothetical protein YP_962981.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_962982.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_962983.1 Involved in cell division; probably involved in intracellular septation YP_962984.1 PFAM: ferric iron reductase; KEGG: son:SO3034 ferric iron reductase protein, putative YP_962985.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_1517 TonB-dependent siderophore receptor YP_962986.1 PFAM: IucA/IucC family protein; KEGG: she:Shewmr4_1452 IucA/IucC family protein YP_962987.1 KEGG: son:SO3031 siderophore biosynthesis protein, putative YP_962988.1 KEGG: shm:Shewmr7_1520 L-lysine 6-monooxygenase (NADPH) YP_962989.1 KEGG: son:SO3029 hypothetical protein YP_962990.1 KEGG: she:Shewmr4_1456 hypothetical protein YP_962991.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_962992.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_962993.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_962994.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_962995.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_962996.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_962997.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; KEGG: she:Shewmr4_1463 PHP C-terminal domain protein YP_962998.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: son:SO3016 Sua5/YciO/YrdC/YwlC family protein YP_962999.1 PFAM: chromosome segregation and condensation protein ScpA; KEGG: son:SO3015 putative segregation and condensation protein A YP_963000.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB; KEGG: shm:Shewmr7_1532 putative transcriptional regulator YP_963001.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: shm:Shewmr7_1533 pseudouridine synthase, Rsu YP_963002.1 KEGG: son:SO2936 hypothetical protein YP_963003.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_1534 short-chain dehydrogenase/reductase SDR YP_963004.1 KEGG: she:Shewmr4_1469 hypothetical protein YP_963005.1 SohB; periplasmic protein; member of the peptidase S49 family YP_963006.1 KEGG: shm:Shewmr7_1542 hypothetical protein YP_963007.1 PFAM: lipolytic enzyme, G-D-S-L family; KEGG: she:Shewmr4_1478 arylesterase YP_963008.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: she:Shewmr4_1479 ABC transporter related YP_963009.1 PFAM: protein of unknown function DUF214; KEGG: son:SO2926 ABC transporter, permease, putative YP_963010.1 PFAM: sodium/glutamate symporter; KEGG: son:SO2923 sodium/glutamate symporter YP_963011.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; domain of unknown function DUF1731; KEGG: shm:Shewmr7_1548 hypothetical protein YP_963012.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_963013.1 PFAM: protein of unknown function UPF0118; KEGG: shm:Shewmr7_1550 protein of unknown function UPF0118 YP_963014.1 KEGG: son:SO2919 hypothetical protein YP_963015.1 KEGG: shm:Shewmr7_1553 hypothetical protein YP_963016.1 KEGG: son:SO2917 hypothetical protein YP_963017.1 KEGG: plu:plu4649 transposase, IS4 family YP_963018.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_963019.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_963020.1 PFAM: protein of unknown function DUF412; KEGG: son:SO2914 hypothetical protein YP_963021.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_963022.1 KEGG: son:SO2912 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL YP_963023.1 KEGG: sfr:Sfri_2472 hypothetical protein YP_963024.1 PFAM: formate/nitrite transporter; CBS domain containing protein; KEGG: sfr:Sfri_2470 formate/nitrite transporter YP_963025.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sfr:Sfri_2469 transcriptional regulator, LysR family protein YP_963026.1 PFAM: C4-dicarboxylate anaerobic carrier; KEGG: shm:Shewmr7_1563 C4-dicarboxylate anaerobic carrier YP_963027.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_2471 TonB-dependent receptor YP_963028.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: son:SO2906 hypothetical protein YP_963029.1 PFAM: O-methyltransferase, family 2; KEGG: shm:Shewmr7_1566 methyltransferase type 12 YP_963030.1 TIGRFAM: cysteine synthases; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: son:SO2903 cysteine synthase A YP_963031.1 PFAM: RDD domain containing protein; KEGG: she:Shewmr4_1501 RDD domain containing protein YP_963032.1 catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_963033.1 putative role in sulfur assimilation YP_963034.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; KEGG: son:SO2898 SMC family protein YP_963035.1 TIGRFAM: cell division protein ZipA; PFAM: ZipA, C-terminal FtsZ-binding region; KEGG: she:Shewmr4_1507 cell division protein ZipA YP_963036.1 KEGG: son:SO2896 DNA ligase, NAD-dependent; TIGRFAM: DNA ligase, NAD-dependent; PFAM: helix-hairpin-helix motif; BRCT domain protein; zinc-finger, NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase, OB-fold; NAD-dependent DNA ligase, adenylation; SMART: Helix-hairpin-helix DNA-binding, class 1; NAD-dependent DNA ligase-like YP_963037.1 KEGG: son:SO2863 hypothetical protein YP_963038.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; KEGG: she:Shewmr4_1510 metal dependent phosphohydrolase YP_963039.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: shm:Shewmr7_1578 NAD-dependent epimerase/dehydratase YP_963040.1 PFAM: DSBA oxidoreductase; KEGG: son:SO2860 thiol:disulfide interchange protein, DsbA family YP_963041.1 KEGG: son:SO2858 hypothetical protein YP_963042.1 PFAM: Na+/solute symporter; KEGG: shm:Shewmr7_1581 Na+/solute symporter YP_963043.1 PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294, nucleotidyltransferase putative; KEGG: shm:Shewmr7_1582 cyclic nucleotide-binding protein YP_963044.1 PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: she:Shewmr4_1516 exonuclease, RNase T and DNA polymerase III YP_963045.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis YP_963046.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: she:Shewmr4_1521 transcriptional regulator, GntR family YP_963047.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_963048.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_963049.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_2435 type III restriction enzyme, res subunit YP_963050.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_963051.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO2742 sensor histidine kinase/response regulator YP_963052.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: vch:VC1248 methyl-accepting chemotaxis protein YP_963053.1 TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: son:SO2741 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_963054.1 KEGG: shm:Shewmr7_2431 biotin synthase; TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_963055.1 PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: son:SO2739 8-amino-7-oxononanoate synthase YP_963056.1 TIGRFAM: biotin biosynthesis protein BioC; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: she:Shewmr4_2357 biotin biosynthesis protein BioC YP_963057.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_963058.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: dar:Daro_4029 TonB-dependent receptor YP_963059.1 PFAM: CobN/magnesium chelatase; KEGG: mma:MM1602 cobalamin biosynthesis protein CobN YP_963060.1 KEGG: mbu:Mbur_2259 hypothetical protein YP_963061.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: mac:MA4426 MotA/TolQ/ExbB proton channel family protein YP_963062.1 KEGG: shm:Shewmr7_2427 hypothetical protein YP_963063.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_963064.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_963065.1 putative metalloprotease YP_963066.1 KEGG: shm:Shewmr7_2388 cytochrome c3 YP_963067.1 PFAM: regulatory protein, LuxR; KEGG: shm:Shewmr7_2386 transcriptional regulator, LuxR family YP_963068.1 KEGG: son:SO2890 hypothetical protein YP_963069.1 PFAM: protein of unknown function DUF307; KEGG: son:SO1977 hypothetical protein YP_963070.1 KEGG: son:SO1978 hypothetical protein YP_963071.1 PFAM: NUDIX hydrolase; KEGG: son:SO1979 MutT/nudix family protein YP_963072.1 KEGG: son:SO1980 phosphoribosyl transferase domain protein; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase YP_963073.1 PFAM: Nicotinate phosphoribosyltransferase and related; KEGG: son:SO1981 hypothetical protein YP_963074.1 KEGG: shm:Shewmr7_2350 hypothetical protein YP_963075.1 KEGG: shm:Shewmr7_2349 hypothetical protein YP_963076.1 TIGRFAM: anti-sigma factor, putative, ChrR family; KEGG: she:Shewmr4_2276 anti-ECFsigma factor, ChrR YP_963077.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: son:SO1986 RNA polymerase sigma-70 factor, ECF subfamily YP_963078.1 PFAM: peptidase S16, lon domain protein; KEGG: shm:Shewmr7_2346 peptidase S16, lon domain protein YP_963079.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO1988 hypothetical methyltransferase YP_963080.1 PFAM: response regulator receiver; CheW domain protein; KEGG: she:Shewmr4_2272 response regulator receiver modulated CheW protein YP_963081.1 KEGG: shm:Shewmr7_2343 hypothetical protein YP_963082.1 KEGG: shm:Shewmr7_2342 hypothetical protein YP_963083.1 TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: she:Shewmr4_2269 lytic murein transglycosylase YP_963084.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO1995 peptidyl-prolyl cis-trans isomerase, FkbP family YP_963085.1 PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: shm:Shewmr7_2339 peptidase M1, membrane alanine aminopeptidase YP_963086.1 KEGG: shm:Shewmr7_2338 hypothetical protein YP_963087.1 PFAM: phospholipase/Carboxylesterase; KEGG: son:SO1999 phospholipase/carboxylesterase family protein YP_963088.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_963089.1 KEGG: shm:Shewmr7_2334 transcriptional regulators, TraR/DksA family YP_963090.1 PFAM: dihydrouridine synthase, DuS; KEGG: shm:Shewmr7_2333 dihydrouridine synthase, DuS YP_963091.1 KEGG: shm:Shewmr7_2332 hypothetical protein YP_963092.1 PFAM: protein of unknown function DUF692; KEGG: son:SO2008 hypothetical protein YP_963093.1 KEGG: she:Shewmr4_2258 hypothetical protein YP_963094.1 KEGG: shm:Shewmr7_2329 hypothetical protein YP_963095.1 PFAM: protein of unknown function DUF454; KEGG: she:Shewmr4_2256 protein of unknown function DUF454 YP_963096.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_963097.1 KEGG: son:SO2013 DNA polymerase III, gamma and tau subunits; TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase YP_963098.1 PFAM: conserved hypothetical protein 103; KEGG: she:Shewmr4_2253 conserved hypothetical protein 103 YP_963099.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_963100.1 molecular chaperone YP_963101.1 PFAM: Thioredoxin domain; KEGG: she:Shewmr4_2250 thioredoxin domain YP_963102.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_963103.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_963104.1 PFAM: PfkB domain protein; KEGG: son:SO2020 inosine-guanosine kinase YP_963105.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_963106.1 KEGG: shm:Shewmr7_2317 hypothetical protein YP_963107.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2297 transcriptional regulator, LysR family YP_963108.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: shm:Shewmr7_2296 NADH:flavin oxidoreductase/NADH oxidase YP_963109.1 PFAM: sulfatase; KEGG: she:Shewmr4_2219 sulfatase YP_963110.2 PFAM: protein of unknown function DUF1414; KEGG: shm:Shewmr7_2294 protein of unknown function DUF1414 YP_963111.1 PFAM: 37 kDa nucleoid-associated protein; KEGG: son:SO2177 hypothetical protein YP_963112.1 PFAM: Di-haem cytochrome c peroxidase; KEGG: son:SO2178 cytochrome c551 peroxidase YP_963113.1 KEGG: shm:Shewmr7_2291 hypothetical protein YP_963114.1 PFAM: peptidase M23B; KEGG: son:SO2180 peptidase, M23/M37 family YP_963115.1 KEGG: shm:Shewmr7_2289 hypothetical protein YP_963116.1 PFAM: protein of unknown function DUF991; KEGG: son:SO2182 hypothetical protein YP_963117.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: shm:Shewmr7_2287 hypothetical protein YP_963118.1 PFAM: Ion transport protein; Ion transport 2 domain protein,; KEGG: she:Shewmr4_2209 ion transport protein YP_963119.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; virulence factor MVIN family protein; KEGG: she:Shewmr4_1623 MATE efflux family protein YP_963120.1 KEGG: son:SO1921 hypothetical protein YP_963121.1 PFAM: uncharacterized conserved protein UCP029143; KEGG: she:Shewmr4_1625 uncharacterized conserved protein UCP029143 YP_963122.1 PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_1627 acriflavin resistance protein YP_963123.1 PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_1628 acriflavin resistance protein YP_963124.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO1925 HlyD family secretion protein YP_963125.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_963126.1 PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: shm:Shewmr7_1706 succinate dehydrogenase, cytochrome b subunit YP_963127.1 KEGG: she:Shewmr4_1632 conserved hypothetical succinate dehydrogenase, hydrophobic subunit YP_963128.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_963129.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_963130.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_963131.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: she:Shewmr4_1636 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase YP_963132.1 catalyzes the interconversion of succinyl-CoA and succinate YP_963133.1 TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: son:SO1933 succinyl-CoA synthetase alpha chain YP_963134.1 PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: shm:Shewmr7_1714 GreA/GreB family elongation factor YP_963135.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1936 acetyltransferase, GNAT family YP_963136.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_963137.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_963138.1 KEGG: she:Shewmr4_1643 hypothetical protein YP_963139.1 KEGG: son:SO1940 hypothetical protein YP_963140.1 TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2+ transporter protein, CorA family protein; KEGG: shm:Shewmr7_1720 magnesium and cobalt transport protein CorA YP_963141.1 KEGG: son:SO1942 HDIG domain protein; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_963142.1 SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: son:SO1944 hypothetical protein YP_963143.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO1945 sensor protein PhoQ YP_963144.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_1655 two component transcriptional regulator, winged helix family YP_963145.1 KEGG: she:Shewmr4_1581 hypothetical protein YP_963146.1 PFAM: sodium:dicarboxylate symporter; KEGG: she:Shewmr4_1582 sodium:dicarboxylate symporter YP_963147.1 PFAM: Ig domain protein, group 1 domain protein; KEGG: sdn:Sden_2330 Ig-like, group 1 YP_963148.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_963149.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_963150.1 KEGG: she:Shewmr4_1586 hypothetical protein YP_963151.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_963152.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: she:Shewmr4_1588 two component transcriptional regulator, LuxR family YP_963153.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_1664 thioesterase superfamily protein YP_963154.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_963155.1 PFAM: protein of unknown function DUF299; KEGG: shm:Shewmr7_1666 protein of unknown function DUF299 YP_963156.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_963157.1 PFAM: FAD linked oxidase domain protein; KEGG: she:Shewmr4_1593 FAD linked oxidase domain protein YP_963158.1 PFAM: transposase Tn5, dimerisation domain protein; KEGG: ppr:PBPRB0910 hypothetical transposase YP_963159.1 PFAM: protein of unknown function DUF1285; KEGG: son:SO2642 hypothetical protein YP_963160.1 PFAM: regulatory protein, MarR; KEGG: son:SO2640 transcriptional regulator, MarR family YP_963161.1 KEGG: shm:Shewmr7_1672 hypothetical protein YP_963162.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: she:Shewmr4_1598 Glu/Leu/Phe/Val dehydrogenase, dimerisation region YP_963163.1 KEGG: son:SO2637 hypothetical protein YP_963164.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji, jmjC domain protein; KEGG: she:Shewmr4_1600 cupin 4 family protein YP_963165.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_963166.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_963167.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_963168.1 PFAM: NUDIX hydrolase; KEGG: son:SO2631 MutT/nudix family protein YP_963169.1 PFAM: pseudouridine synthase; KEGG: she:Shewmr4_1605 pseudouridine synthase, Rsu YP_963170.1 KEGG: shm:Shewmr7_1681 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type YP_963171.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_963172.1 KEGG: son:SO2626 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_963173.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_963174.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_963175.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_963176.1 PFAM: 17 kDa surface antigen; KEGG: she:Shewmr4_1652 17 kDa surface antigen YP_963177.1 PFAM: protein of unknown function DUF34; KEGG: son:SO2621 conserved hypothetical protein TIGR00486 YP_963178.1 PFAM: Auxin Efflux Carrier; KEGG: she:Shewmr4_1654 auxin efflux carrier YP_963179.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_963180.1 KEGG: son:SO2618 ATP-binding protein, Mrp/Nbp35 family YP_963181.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_963182.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_963183.1 PFAM: aminotransferase, class IV; KEGG: son:SO2615 4-amino-4-deoxychorismate lyase YP_963184.1 PFAM: aminodeoxychorismate lyase; KEGG: shm:Shewmr7_1735 aminodeoxychorismate lyase YP_963185.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_963186.1 TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: she:Shewmr4_1662 DNA polymerase III, delta prime subunit YP_963187.1 KEGG: shm:Shewmr7_1738 type IV pilus biogenesis protein PilZ YP_963188.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: shm:Shewmr7_1739 hydrolase, TatD family YP_963189.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_963190.1 PFAM: nucleoside recognition domain protein; KEGG: she:Shewmr4_1666 nucleoside recognition domain protein YP_963191.1 PFAM: Mammalian cell entry related domain protein; KEGG: she:Shewmr4_1667 mammalian cell entry related domain protein YP_963192.1 PFAM: Paraquat-inducible protein A; KEGG: shm:Shewmr7_1743 paraquat-inducible protein A YP_963193.1 PFAM: Paraquat-inducible protein A; KEGG: she:Shewmr4_1669 paraquat-inducible protein A YP_963194.1 PFAM: YebG family protein; KEGG: shm:Shewmr7_1745 YebG family protein YP_963195.1 PFAM: GAF domain protein; KEGG: shm:Shewmr7_1746 putative GAF sensor protein YP_963196.1 affects solute and DNA transport through an unknown mechanism YP_963197.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_963198.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: she:Shewmr4_1674 aminopeptidase N YP_963199.1 KEGG: son:SO2598 hypothetical protein YP_963200.1 PFAM: protein of unknown function DUF1302; KEGG: son:SO2597 hypothetical protein YP_963201.1 PFAM: protein of unknown function DUF1329; KEGG: she:Shewmr4_1677 protein of unknown function DUF1329 YP_963202.1 KEGG: son:SO2595 BNR repeat protein YP_963203.1 KEGG: shm:Shewmr7_1754 hypothetical protein YP_963204.1 PFAM: NAD-glutamate dehydrogenase; KEGG: shm:Shewmr7_1755 NAD-glutamate dehydrogenase YP_963205.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_963206.1 PFAM: protein of unknown function DUF1379; KEGG: she:Shewmr4_1682 protein of unknown function DUF1379 YP_963207.1 KEGG: vpa:VP1842 RelB protein YP_963210.1 PFAM: uncharacterized conserved protein UCP025560; KEGG: shm:Shewmr7_2188 uncharacterized conserved protein UCP025560 YP_963211.1 KEGG: son:SO2063 hypothetical protein YP_963212.1 KEGG: she:Shewmr4_1791 hypothetical protein YP_963213.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter, transmembrane; KEGG: she:Shewmr4_1792 aromatic amino acid transporter YP_963214.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_963215.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_963216.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_963217.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_963218.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_963219.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_963220.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_963221.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_963222.1 PFAM: protein of unknown function DUF938; KEGG: son:SO2050 hypothetical protein YP_963223.1 PFAM: FAD dependent oxidoreductase; KEGG: shm:Shewmr7_2193 FAD dependent oxidoreductase YP_963224.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2192 transcriptional regulator, LysR family YP_963225.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: shm:Shewmr7_2191 alcohol dehydrogenase, zinc-binding domain protein YP_963226.1 PFAM: putative esterase; KEGG: shm:Shewmr7_2190 carboxylesterase YP_963227.1 KEGG: shm:Shewmr7_1804 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_963228.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_963229.1 PFAM: protein of unknown function UPF0227; KEGG: son:SO2251 conserved hypothetical protein YP_963230.1 PFAM: protein of unknown function UPF0167; KEGG: son:SO0898 hypothetical protein YP_963231.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pat:Patl_0928 GCN5-related N-acetyltransferase YP_963232.1 KEGG: atc:AGR_L_16 hypothetical protein YP_963233.1 KEGG: atc:AGR_L_17 hypothetical protein YP_963234.1 PFAM: putative transposase; KEGG: son:SO2212 transposase, IS91 family, putative YP_963235.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: son:SO2036 site-specific recombinase, phage integrase family YP_963236.1 KEGG: she:Shewmr4_1443 hypothetical protein YP_963237.1 KEGG: son:SO1424 hypothetical protein YP_963238.1 KEGG: son:SO1425 hypothetical protein YP_963239.1 PFAM: transposase Tn5, dimerisation domain protein; KEGG: ppr:PBPRB0910 hypothetical transposase YP_963240.1 catalyzes the hydrolysis of acylphosphate YP_963241.1 KEGG: son:SO2254 hypothetical protein YP_963242.1 KEGG: shm:Shewmr7_1810 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_963243.1 KEGG: son:SO2256 hypothetical protein YP_963244.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: she:Shewmr4_1732 lipoprotein releasing system, transmembrane protein, LolC/E family YP_963245.1 KEGG: shm:Shewmr7_1813 lipoprotein releasing system, ATP-binding protein; TIGRFAM: lipoprotein releasing system, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase YP_963246.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: she:Shewmr4_1734 lipoprotein releasing system, transmembrane protein, LolC/E family YP_963247.1 PFAM: inositol monophosphatase; KEGG: shm:Shewmr7_1815 inositol-phosphate phosphatase YP_963248.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: son:SO2261 RNA methyltransferase, TrmH family, group 1 YP_963249.1 TIGRFAM: serine O-acetyltransferase; KEGG: shm:Shewmr7_1817 serine O-acetyltransferase YP_963250.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; iron-sulfur cluster assembly transcription factor IscR; PFAM: protein of unknown function UPF0074; KEGG: son:SO2263 Rrf2 family protein YP_963251.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_963252.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: shm:Shewmr7_1820 FeS cluster assembly scaffold IscU YP_963253.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; iron-sulfur cluster assembly protein IscA; PFAM: HesB/YadR/YfhF-family protein; KEGG: shm:Shewmr7_1821 iron-sulfur cluster assembly protein IscA YP_963254.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_963255.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_963256.1 TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: shm:Shewmr7_1824 ferredoxin, 2Fe-2S type, ISC system YP_963257.1 TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: shm:Shewmr7_1825 alpha-L-glutamate ligases, RimK family YP_963258.1 PFAM: protein of unknown function DUF528; KEGG: shm:Shewmr7_1826 protein of unknown function DUF528 YP_963259.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_963260.1 PFAM: heat shock protein Hsp20; KEGG: son:SO2277 16 kDa heat shock protein A YP_963261.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_963262.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: she:Shewmr4_1750 acetolactate synthase, large subunit, biosynthetic type YP_963264.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_1751 drug resistance transporter, Bcr/CflA subfamily YP_963265.1 KEGG: she:Shewmr4_1752 alkaline phosphatase YP_963266.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: she:Shewmr4_1753 transcriptional regulator, GntR family YP_963267.1 KEGG: shm:Shewmr7_1834 lysine exporter protein (LysE/YggA) YP_963268.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; sulphate transporter; KEGG: she:Shewmr4_1755 sulphate transporter YP_963269.1 KEGG: shm:Shewmr7_1836 hypothetical protein YP_963270.1 PFAM: Rhodanese domain protein; KEGG: she:Shewmr4_1760 rhodanese domain protein YP_963271.1 KEGG: shm:Shewmr7_1839 hypothetical protein YP_963272.1 KEGG: son:SO2479 hypothetical protein YP_963273.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_963274.1 PFAM: carbonic anhydrase; KEGG: she:Shewmr4_1854 carbonate dehydratase YP_963275.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO2473 hydrolase, alpha/beta fold family YP_963276.1 PFAM: peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins; KEGG: son:SO2472 D-alanyl-D-alanine carboxypeptidase-related protein YP_963277.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_963278.1 PFAM: arsenate reductase; KEGG: shm:Shewmr7_2120 hypothetical protein YP_963279.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis protein domain protein; KEGG: vvu:VV21623 methyl-accepting chemotaxis protein YP_963280.1 KEGG: plu:plu4649 transposase, IS4 family YP_963281.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_963282.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein; KEGG: she:Shewmr4_1764 phosphoenolpyruvate-protein phosphotransferase YP_963283.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: son:SO2238 phosphocarrier protein HPr YP_963284.1 KEGG: shm:Shewmr7_1844 hypothetical protein YP_963285.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: shm:Shewmr7_1845 methyl-accepting chemotaxis sensory transducer YP_963286.1 KEGG: son:SO2241 hypothetical protein YP_963287.1 KEGG: son:SO2245 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_963288.1 KEGG: son:SO2146 hypothetical protein YP_963289.1 KEGG: shm:Shewmr7_1851 exodeoxyribonuclease V, alpha subunit; TIGRFAM: exodeoxyribonuclease V, alpha subunit; SMART: AAA ATPase YP_963290.1 TIGRFAM: exodeoxyribonuclease V, beta subunit; PFAM: UvrD/REP helicase; KEGG: shm:Shewmr7_1852 exodeoxyribonuclease V, beta subunit YP_963291.1 TIGRFAM: exodeoxyribonuclease V, gamma subunit; PFAM: Exodeoxyribonuclease V, RecC subunit; KEGG: she:Shewmr4_1775 exodeoxyribonuclease V, gamma subunit YP_963292.1 PFAM: transglutaminase domain protein; KEGG: son:SO2150 transglutaminase family protein YP_963293.1 PFAM: protein of unknown function DUF58; KEGG: shm:Shewmr7_1855 protein of unknown function DUF58 YP_963294.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; KEGG: son:SO2153 MoxR protein YP_963295.1 PFAM: EAL domain protein; KEGG: she:Shewmr4_2112 diguanylate phosphodiesterase YP_963296.1 PFAM: Lytic transglycosylase, catalytic; KEGG: shm:Shewmr7_1863 lytic transglycosylase, catalytic YP_963297.1 PFAM: protein of unknown function DUF195; KEGG: son:SO2041 hypothetical protein YP_963298.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_963299.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_963300.1 KEGG: son:SO2044 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_963301.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: shm:Shewmr7_1868 cation diffusion facilitator family transporter YP_963302.1 PFAM: regulatory protein, MarR; KEGG: shm:Shewmr7_1869 transcriptional regulator, MarR family YP_963303.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller; KEGG: son:SO2047 prolyl oligopeptidase family protein YP_963304.1 PFAM: sulfatase; protein of unknown function DUF1705; KEGG: she:Shewmr4_2103 sulfatase YP_963305.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_1872 diguanylate cyclase YP_963306.1 PFAM: UspA domain protein; KEGG: pat:Patl_2285 UspA YP_963307.1 PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: pat:Patl_2284 sodium/hydrogen exchanger YP_963308.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC, N-terminal domain; zinc finger, HypF domain protein; KEGG: son:SO2094 hydrogenase maturation protein HypF YP_963309.1 KEGG: son:SO2095 hypothetical protein YP_963310.1 TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; PFAM: peptidase M52, hydrogen uptake protein; KEGG: son:SO2096 hydrogenase expression/formation protein YP_963311.1 TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: shm:Shewmr7_2157 Ni/Fe-hydrogenase, b-type cytochrome subunit YP_963312.1 PFAM: nickel-dependent hydrogenase, large subunit; KEGG: son:SO2098 hydrogenase large chain YP_963313.1 KEGG: son:SO2099 hydrogenase small chain; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Nickel-iron dehydrogenase small subunit, N-terminal domain protein YP_963314.1 PFAM: Redoxin domain protein; KEGG: shm:Shewmr7_2154 redoxin domain protein YP_963315.1 KEGG: shm:Shewmr7_2153 lipoprotein, putative YP_963316.1 KEGG: shm:Shewmr7_2152 hypothetical protein YP_963317.1 PFAM: ApbE family lipoprotein; KEGG: son:SO2103 ApbE family protein YP_963318.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO2104 DNA-binding response regulator YgiX, putative YP_963319.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO2105 sensor protein YgiY, putative YP_963320.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_963321.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_963322.1 converts asparagine to aspartate and ammonia YP_963323.1 TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; KEGG: she:Shewmr4_1909 signal peptide peptidase SppA, 67K type YP_963324.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_1910 NADH:flavin oxidoreductase/NADH oxidase YP_963325.1 PFAM: YCII-related protein; KEGG: hne:HNE_0837 YCII domain protein YP_963326.1 PFAM: ferredoxin; KEGG: shm:Shewmr7_2064 ferredoxin YP_963327.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_963328.1 Catalyzes the rate-limiting step in dNTP synthesis YP_963329.1 KEGG: shm:Shewmr7_2061 HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_963330.1 Involved in ubiquinone biosynthesis YP_963331.1 TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal repeat, beta-propeller; KEGG: she:Shewmr4_1919 DNA gyrase, A subunit YP_963332.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_963333.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_963334.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_963335.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_963336.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; beta-phosphoglucomutase family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_1994 HAD-superfamily hydrolase, subfamily IA, variant 3 YP_963337.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: shm:Shewmr7_1993 GntR domain protein YP_963338.1 PFAM: glycoside hydrolase, family 43; KEGG: she:Shewmr4_1982 glycoside hydrolase, family 43 YP_963339.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_963340.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: she:Shewmr4_1984 short-chain dehydrogenase/reductase SDR YP_963341.1 PFAM: Aldose 1-epimerase; KEGG: shm:Shewmr7_1989 aldose 1-epimerase YP_963342.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: shm:Shewmr7_1988 periplasmic binding protein/LacI transcriptional regulator YP_963343.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_1987 ABC transporter related YP_963344.1 PFAM: inner-membrane translocator; KEGG: shm:Shewmr7_1986 inner-membrane translocator YP_963345.1 membrane component of a putative sugar ABC transporter system YP_963346.1 PFAM: glycoside hydrolase, family 43; KEGG: shm:Shewmr7_1984 alpha-N-arabinofuranosidase YP_963347.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: pfl:PFL_1735 methyl-accepting chemotaxis protein YP_963348.1 PFAM: glycoside hydrolase, family 43; KEGG: sde:Sde_0777 ribosomal protein L11 methyltransferase YP_963349.1 TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_1994 sugar (glycoside-pentoside-hexuronide) transporter YP_963350.1 PFAM: glycoside hydrolase, family 43; KEGG: shm:Shewmr7_1980 arabinan endo-1,5-alpha-L-arabinosidase YP_963351.1 PFAM: Ricin B lectin; glycoside hydrolase, family 43; KEGG: she:Shewmr4_1996 glycoside hydrolase, family 43 YP_963352.1 PFAM: protein of unknown function DUF81; KEGG: she:Shewmr4_1997 protein of unknown function DUF81 YP_963353.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_1977 TonB-dependent receptor YP_963354.1 PFAM: glycoside hydrolase, family 43; KEGG: she:Shewmr4_1999 glycoside hydrolase, family 43 YP_963355.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: shm:Shewmr7_1974 SMP-30/gluconolaconase/LRE domain protein YP_963356.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_963357.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_963358.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_963359.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_963360.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_963361.1 PFAM: protein of unknown function DUF1049; KEGG: shm:Shewmr7_2052 protein of unknown function DUF1049 YP_963362.1 KEGG: son:SO2399 hypothetical protein YP_963363.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_963364.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: shm:Shewmr7_2049 short-chain dehydrogenase/reductase SDR YP_963365.1 KEGG: she:Shewmr4_1930 hypothetical protein YP_963366.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: she:Shewmr4_1931 acyl-CoA dehydrogenase domain protein YP_963367.1 KEGG: shm:Shewmr7_2044 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C YP_963368.1 KEGG: shm:Shewmr7_2043 hypothetical protein YP_963369.1 KEGG: shm:Shewmr7_2042 hypothetical protein YP_963370.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_963371.1 multidrug efflux protein involved in adaptation to low energy shock YP_963372.1 PFAM: beta-lactamase; KEGG: shm:Shewmr7_2039 beta-lactamase YP_963373.1 PFAM: DTW domain containing protein; KEGG: son:SO2387 conserved hypothetical protein YP_963374.1 PFAM: protein of unknown function DUF839; KEGG: shm:Shewmr7_2034 twin-arginine translocation pathway signal YP_963375.1 KEGG: she:Shewmr4_1945 hypothetical protein YP_963376.1 KEGG: shm:Shewmr7_2030 ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_963377.1 KEGG: vfi:VF0709 hypothetical protein YP_963378.1 serine protease inhibitor, inhibits trypsin and other proteases YP_963379.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: shm:Shewmr7_2025 MATE efflux family protein YP_963380.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_963381.1 KEGG: shm:Shewmr7_2023 hypothetical protein YP_963382.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_963383.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_963384.1 PFAM: ribosomal protein L35; KEGG: sdn:Sden_1707 ribosomal protein L35 YP_963385.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_963386.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO2303 thioredoxin reductase YP_963387.1 TIGRFAM: alanine dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Shikimate/quinate 5-dehydrogenase; alanine dehydrogenase/PNT domain protein; KEGG: shm:Shewmr7_2015 alanine dehydrogenase YP_963388.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_963389.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: shm:Shewmr7_2013 cell divisionFtsK/SpoIIIE YP_963390.1 PFAM: outer membrane lipoprotein carrier protein LolA; KEGG: shm:Shewmr7_2012 outer membrane lipoprotein carrier protein LolA YP_963391.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: son:SO2308 ATPase, AAA family YP_963392.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_963393.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_963394.1 KEGG: shm:Shewmr7_2008 hypothetical protein YP_963395.1 PFAM: DsrC family protein; KEGG: she:Shewmr4_1969 DsrC family protein YP_963396.1 PFAM: DsrH family protein; KEGG: son:SO2378 putative uncharacterized protein involved in oxidation of intracellular sulfur YP_963397.1 PFAM: DsrE family protein; KEGG: shm:Shewmr7_2005 DsrE family protein YP_963398.1 PFAM: DsrE family protein; KEGG: shm:Shewmr7_2004 DsrE family protein YP_963399.1 PFAM: protein of unknown function UPF0005; KEGG: son:SO2375 membrane protein, putative YP_963400.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_1974 transcriptional regulator, LysR family YP_963401.1 uncharacterized member of the major facilitator superfamily (MFS) YP_963403.1 KEGG: rpc:RPC_3570 sec-C metal-binding protein YP_963404.1 KEGG: ppr:PBPRB_2026 hypothetical protein YP_963405.1 KEGG: psb:Psyr_4515 hypothetical protein YP_963406.1 PFAM: transposase Tn3 family protein; KEGG: pol:Bpro_2512 transposase Tn3 YP_963409.1 PFAM: phage integrase family protein; KEGG: xcv:XCV2438 cointegrate resolution protein S YP_963410.1 KEGG: vch:VCA0487 hypothetical protein YP_963411.1 KEGG: vch:VCA0486 hypothetical protein YP_963412.1 KEGG: pol:Bpro_2488 cointegrate resolution protein T YP_963413.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: mxa:MXAN_0073 thioesterase family domain protein YP_963414.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: sfr:Sfri_1524 thioesterase superfamily protein YP_963415.1 PFAM: aldo/keto reductase; KEGG: rsp:RSP_3201 putative oxidoreductase YP_963416.1 PFAM: regulatory protein, TetR; KEGG: ret:RHE_CH02697 probable transcriptional regulator protein, TetR family YP_963417.1 KEGG: jan:Jann_4157 anti-sigma factor, ChrR YP_963418.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: pat:Patl_4128 glutathione S-transferase-like YP_963419.1 KEGG: ilo:IL1253 hypothetical protein YP_963421.1 KEGG: sfr:Sfri_3147 transposase, IS4 family protein YP_963422.1 PFAM: Integrase, catalytic region; KEGG: vpa:VP1787 putative transposase YP_963423.1 PFAM: transposase, IS4 family protein; KEGG: lpn:lpg1315 transposase YP_963424.1 PFAM: chemotaxis sensory transducer; KEGG: ilo:IL1068 methyl-accepting chemotaxis protein with ligand-binding sensor domain and HAMP domain YP_963425.1 PFAM: regulatory protein, TetR; KEGG: ret:RHE_CH00601 probable transcriptional regulator protein, TetR family YP_963426.1 PFAM: Endoribonuclease L-PSP; KEGG: atc:AGR_C_2721 hypothetical protein YP_963427.1 PFAM: transposase, IS4 family protein; KEGG: lpn:lpg1315 transposase YP_963428.1 KEGG: son:SO2365 hypothetical protein YP_963429.1 CcoN; FixN YP_963430.1 CcoO; FixO YP_963431.1 PFAM: Cbb3-type cytochrome oxidase component; KEGG: shm:Shewmr7_1967 Cbb3-type cytochrome oxidase component YP_963432.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III; PFAM: cytochrome c, class I; KEGG: shm:Shewmr7_1966 cytochrome c oxidase, cbb3-type, subunit III YP_963433.1 KEGG: son:SO2360 hypothetical protein YP_963434.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: she:Shewmr4_2011 heavy metal translocating P-type ATPase YP_963435.1 TIGRFAM: cytochrome oxidase maturation protein, cbb3-type; PFAM: cytochrome oxidase maturation protein cbb3-type; KEGG: shm:Shewmr7_1963 cytochrome oxidase maturation protein, cbb3-type YP_963436.1 KEGG: son:SO2357 hypothetical protein YP_963437.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_963438.1 with UspC and UspD is involved in resistance to UV irradiation YP_963439.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_963440.1 KEGG: son:SO2353 hypothetical protein YP_963441.1 KEGG: she:Shewmr4_2018 bax protein, putative YP_963442.1 PFAM: protein of unknown function UPF0052 and CofD; KEGG: shm:Shewmr7_1956 hypothetical protein YP_963443.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_963444.1 PFAM: protein of unknown function DUF1315; KEGG: son:SO2422 hypothetical protein YP_963445.1 KEGG: shm:Shewmr7_2072 hypothetical protein YP_963446.1 PFAM: peptidase M14, carboxypeptidase A; KEGG: shm:Shewmr7_2073 peptidase M14, carboxypeptidase A YP_963447.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO2426 DNA-binding response regulator YP_963448.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_963449.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_963450.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_1903 TonB-dependent receptor YP_963451.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_963452.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_963453.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_963454.1 PFAM: protein of unknown function DUF28; KEGG: shm:Shewmr7_2079 protein of unknown function DUF28 YP_963455.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_963456.1 KEGG: she:Shewmr4_1897 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: extracellular solute-binding protein, family 3 YP_963457.1 TIGRFAM: putative methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: she:Shewmr4_1896 putative methyltransferase YP_963458.1 TIGRFAM: putative methyltransferase; PFAM: methyltransferase, putative; Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_2083 putative methyltransferase YP_963459.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: shm:Shewmr7_2087 hypothetical protein YP_963460.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2438 transcriptional regulator, LysR family YP_963461.1 KEGG: shm:Shewmr7_2090 SrpA-related protein YP_963462.1 KEGG: son:SO2439.2 hypothetical methyl-accepting chemotaxis protein YP_963463.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_963464.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_963465.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: son:SO2442 thiS protein, putative YP_963466.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: she:Shewmr4_1883 UBA/ThiF-type NAD/FAD binding protein YP_963467.1 KEGG: shm:Shewmr7_2096 thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1 YP_963468.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_963469.1 KEGG: son:SO2446 hypothetical protein YP_963470.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: she:Shewmr4_1879 channel protein, hemolysin III family YP_963471.1 PFAM: DTW domain containing protein; KEGG: sfr:Sfri_1306 DTW domain containing protein YP_963472.1 PFAM: NUDIX hydrolase; KEGG: son:SO2448 MutT/nudix family protein YP_963473.1 KEGG: cvi:CV2953 hypothetical protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_963474.1 KEGG: son:SO2449 hypothetical protein YP_963475.1 PFAM: UspA domain protein; KEGG: sfr:Sfri_2734 hypothetical protein YP_963476.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: she:Shewmr4_1875 transcriptional regulator, AraC family YP_963477.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: shm:Shewmr7_2104 alkylhydroperoxidase like protein, AhpD family YP_963478.1 KEGG: shm:Shewmr7_2105 hypothetical protein YP_963479.1 PFAM: YCII-related protein; KEGG: son:SO2457 hypothetical protein YP_963480.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: shm:Shewmr7_2110 transcriptional regulator, AraC family YP_963481.1 PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: shm:Shewmr7_2111 sodium/sulphate symporter YP_963482.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji, jmjC domain protein; KEGG: cps:CPS_2133 hypothetical protein YP_963483.1 KEGG: son:SO2234 hypothetical protein YP_963484.1 KEGG: rba:RB11509 hypothetical protein YP_963485.1 TIGRFAM: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family; PFAM: NapC/NirT cytochrome c domain protein; KEGG: shm:Shewmr7_2133 periplasmic nitrate (or nitrite) reductase C-type cytochrome, NapC/NirT family YP_963486.1 PFAM: Nitrate reductase cytochrome c-type subunit (NapB); KEGG: she:Shewmr4_1843 nitrate reductase cytochrome c-type subunit (NapB) YP_963487.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_963488.1 PFAM: NapD family protein; KEGG: shm:Shewmr7_2136 NapD family protein YP_963489.1 PFAM: periplasmic nitrate reductase NapE; KEGG: shm:Shewmr7_2137 periplasmic nitrate reductase NapE YP_963490.1 KEGG: shm:Shewmr7_2138 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD-like helicases-like YP_963491.1 PFAM: CBS domain containing protein; KEGG: shm:Shewmr7_2139 putative signal transduction protein with CBS domains YP_963492.1 PFAM: peptidase T2, asparaginase 2; KEGG: shm:Shewmr7_2140 peptidase T2, asparaginase 2 YP_963493.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: son:SO2114 hypothetical protein YP_963494.1 PFAM: protein of unknown function DUF490; KEGG: she:Shewmr4_1835 protein of unknown function DUF490 YP_963495.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_963496.1 KEGG: son:SO2111 hypothetical protein YP_963497.1 PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: son:SO2110 hypothetical protein YP_963498.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: son:SO2109 hypothetical protein YP_963499.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent YP_963500.1 KEGG: she:Shewmr4_2022 hypothetical protein YP_963501.1 KEGG: son:SO2345 glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_963502.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_963503.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: shm:Shewmr7_1949 catalytic domain of components of various dehydrogenase complexes YP_963504.1 PFAM: Transketolase, central region; Transketolase domain protein; KEGG: shm:Shewmr7_1948 transketolase, central region YP_963505.1 PFAM: dehydrogenase, E1 component; KEGG: shm:Shewmr7_1947 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) YP_963506.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_963507.1 KEGG: shm:Shewmr7_1945 peptide methionine sulfoxide reductase; TIGRFAM: peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A YP_963508.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_963509.1 negative modulator of the initiation of chromosome replication YP_963510.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: shm:Shewmr7_1942 alpha/beta hydrolase fold YP_963511.1 KEGG: shm:Shewmr7_1941 hypothetical protein YP_963512.1 KEGG: shm:Shewmr7_1940 CopG domain protein DNA-binding domain protein YP_963513.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_963514.1 KEGG: shm:Shewmr7_1938 hypothetical protein YP_963515.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_963516.1 KEGG: she:Shewmr4_1801 hypothetical protein YP_963517.1 PFAM: Na+/H+ antiporter NhaC; KEGG: shm:Shewmr7_1936 Na+/H+ antiporter NhaC YP_963518.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_963519.1 KEGG: shm:Shewmr7_1934 metal dependent phosphohydrolase YP_963520.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_963521.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_963522.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_963523.1 TIGRFAM: 6-phosphogluconolactonase; KEGG: son:SO2488 6-phosphogluconolactonase YP_963524.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_963525.1 Represses the expression of the zwf, eda, glp and gap YP_963526.1 PFAM: pyruvate kinase; KEGG: shm:Shewmr7_1927 pyruvate kinase YP_963527.1 PFAM: transposase Tn5, dimerisation domain protein; KEGG: ppr:PBPRB0910 hypothetical transposase YP_963528.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_963529.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_1925 transcriptional regulator, TetR family YP_963530.1 PFAM: Smr protein/MutS2; KEGG: she:Shewmr4_2052 Smr protein/MutS2 YP_963531.1 KEGG: she:Shewmr4_2053 hypothetical protein YP_963532.1 PFAM: SEC-C motif domain protein; KEGG: shm:Shewmr7_1921 sec-C motif domain protein YP_963533.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; PAS fold domain protein; KEGG: she:Shewmr4_2055 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) YP_963534.1 KEGG: son:SO2499 hypothetical protein YP_963535.1 KEGG: she:Shewmr4_2057 hypothetical protein YP_963536.1 KEGG: son:SO2501 radical activating enzyme YP_963537.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_963538.1 PFAM: Rhomboid family protein; KEGG: she:Shewmr4_2060 rhomboid family protein YP_963539.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_963540.1 PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: shm:Shewmr7_1912 diguanylate cyclase/phosphodiesterase YP_963541.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: shm:Shewmr7_1911 electron transport complex, RnfABCDGE type, A subunit YP_963542.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_963543.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_963544.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_963545.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_963546.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_963547.1 KEGG: she:Shewmr4_2070 endonuclease III; TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_963548.1 KEGG: she:Shewmr4_2075 hypothetical protein YP_963549.1 PFAM: Propeptide, PepSY amd peptidase M4; PepSY-associated TM helix domain protein; KEGG: shm:Shewmr7_1899 PepSY-associated TM helix domain protein YP_963550.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: ilo:IL2511 outer membrane receptor for ferric siderophore YP_963551.1 KEGG: shm:Shewmr7_1896 hypothetical protein YP_963552.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO2525 ABC transporter, ATP-binding protein YP_963553.1 KEGG: pfl:PFL_3338 hypothetical protein YP_963554.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: she:Shewmr4_2098 CoA-binding domain protein YP_963555.1 TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K; KEGG: son:SO2093 hydrogenase accessory protein HypB YP_963556.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: son:SO2092 hydrogenase assembly chaperone hypC/hupF YP_963557.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: son:SO2091 hydrogenase expression/formation protein HypD YP_963558.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: shm:Shewmr7_2164 hydrogenase expression/formation protein HypE YP_963559.1 TIGRFAM: hydrogenase nickel insertion protein HypA; PFAM: hydrogenase expression/synthesis, HypA; KEGG: shm:Shewmr7_2165 hydrogenase nickel insertion protein HypA YP_963560.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_963561.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_963562.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_963563.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_963564.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_2170 methyl-accepting chemotaxis sensory transducer YP_963565.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_1806 TonB-dependent receptor YP_963566.1 KEGG: shm:Shewmr7_2388 cytochrome c3 YP_963567.1 SMART: helicase c2; KEGG: shm:Shewmr7_2172 helicase C2 YP_963568.1 TIGRFAM: CRISPR-associated protein, Csy4 family; KEGG: zmo:ZMO0685 hypothetical protein YP_963569.1 TIGRFAM: CRISPR-associated protein, Csy3 family; KEGG: lpf:lpl2841 hypothetical protein YP_963570.1 TIGRFAM: CRISPR-associated protein, Csy2 family; KEGG: lpf:plpl0049 hypothetical protein YP_963571.1 TIGRFAM: CRISPR-associated protein, Csy1 family; KEGG: lpf:lpl2839 hypothetical protein YP_963572.1 TIGRFAM: CRISPR-associated helicase Cas3 family; KEGG: lpf:lpl2838 hypothetical protein YP_963573.1 TIGRFAM: CRISPR-associated protein Cas1; KEGG: ppr:PBPRB1995 hypothetical protein YP_963574.1 PFAM: beta-lactamase; KEGG: pae:PA2315 hypothetical protein YP_963575.1 PFAM: major facilitator superfamily MFS_1; KEGG: pfo:Pfl_3692 general substrate transporter YP_963576.1 PFAM: major facilitator superfamily MFS_1; KEGG: bur:Bcep18194_A4906 major facilitator superfamily (MFS_1) transporter YP_963577.1 KEGG: psb:Psyr_4511 hypothetical protein YP_963578.1 PFAM: protein of unknown function DUF955; KEGG: ilo:IL2196 predicted metal-dependent peptidase YP_963581.1 PFAM: Resolvase, N-terminal domain; Resolvase helix-turn-helix domain protein; KEGG: gsu:GSU1711 integrative genetic element Gsu5, resolvase YP_963582.1 KEGG: vch:VC0508 hypothetical protein YP_963583.1 PFAM: DNA repair protein RadC; KEGG: vvy:VV2251 DNA repair protein YP_963586.1 TIGRFAM: phage/plasmid primase, P4 family; PFAM: Poxvirus D5 protein; TOPRIM domain protein; DNA primase catalytic core, N-terminal domain; KEGG: lin:lin2587 similar to bacteriophage protein YP_963587.1 SMART: protein phosphatase 2C domain protein; KEGG: sty:STY4824 hypothetical protein YP_963588.1 PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: stt:t4520 protein kinase YP_963589.1 PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: stt:t4519 protein kinase YP_963590.1 PFAM: phage integrase family protein; KEGG: vpa:VP0643 hypothetical protein YP_963591.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Nitrate and nitrite sensing domain protein; KEGG: shm:Shewmr7_1760 methyl-accepting chemotaxis sensory transducer YP_963592.1 PFAM: multiple antibiotic resistance (MarC)-related proteins; KEGG: son:SO2137 multiple antibiotic resistance protein YP_963593.1 PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: she:Shewmr4_1683 iron-containing alcohol dehydrogenase YP_963594.1 KEGG: she:Shewmr4_2121 hypothetical protein YP_963595.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_2122 GCN5-related N-acetyltransferase YP_963596.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: shm:Shewmr7_2199 peptidase S9, prolyl oligopeptidase active site domain protein YP_963597.1 TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; Fe-S type hydro-lyases tartrate/fumarate beta region; KEGG: son:SO2222 fumarate hydratase, class I, anaerobic, putative YP_963598.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein; KEGG: son:SO2221 para-aminobenzoate synthase, component I YP_963599.1 PFAM: NUDIX hydrolase; KEGG: she:Shewmr4_2126 NUDIX hydrolase YP_963600.1 KEGG: shm:Shewmr7_2203 hypothetical protein YP_963601.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_963602.1 SMART: extracellular solute-binding protein, family 3; KEGG: dvu:DVU0852 extracellular solute-binding protein, putative YP_963603.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_963604.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; PAS fold domain protein; KEGG: she:Shewmr4_2130 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) YP_963605.1 PFAM: Fmu (Sun) domain protein; KEGG: she:Shewmr4_2131 Fmu (Sun) domain protein YP_963606.1 KEGG: cgb:cg2479 hypothetical protein YP_963607.1 KEGG: shm:Shewmr7_2218 hypothetical protein YP_963608.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_963609.1 PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase; KEGG: shm:Shewmr7_2220 methylated-DNA-(protein)-cysteine S-methyltransferase YP_963610.1 KEGG: son:SO2533 hypothetical protein YP_963611.1 PFAM: glutamine amidotransferase, class-II; KEGG: shm:Shewmr7_2222 glutamine amidotransferase, class-II YP_963612.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_963613.1 PFAM: PRC-barrel domain protein; KEGG: net:Neut_2352 PRC-barrel domain protein YP_963614.1 KEGG: rfr:Rfer_1879 hypothetical protein YP_963615.1 PFAM: transport-associated; KEGG: son:SO2549 hypothetical protein YP_963616.1 KEGG: son:SO2550 transcriptional regulator-related protein YP_963617.1 PFAM: cyclic nucleotide-binding; KEGG: son:SO2551 transcriptional regulator-related protein YP_963618.1 KEGG: son:SO2552 hypothetical protein YP_963619.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria; KEGG: son:SO2553 hyperosmotically inducible periplasmic protein YP_963620.1 KEGG: son:SO2554 hypothetical protein YP_963621.1 PFAM: OmpA/MotB domain protein; KEGG: noc:Noc_2042 OmpA/MotB YP_963622.1 KEGG: shm:Shewmr7_2233 hypothetical protein YP_963623.1 KEGG: son:SO2559 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_963624.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_963625.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2236 transcriptional regulator, LysR family YP_963626.1 PFAM: Methyltransferase type 11; KEGG: she:Shewmr4_2160 methyltransferase type 11 YP_963627.1 PFAM: beta-lactamase domain protein; KEGG: shm:Shewmr7_2238 hydroxyacylglutathione hydrolase YP_963628.1 PFAM: Peptidoglycan-binding LysM; Lytic transglycosylase, catalytic; MLTD_N domain protein; KEGG: shm:Shewmr7_2239 MLTD_N domain protein YP_963629.1 KEGG: shm:Shewmr7_2240 intracellular proteinase inhibitor domain protein YP_963630.1 PFAM: AsmA family protein; KEGG: shm:Shewmr7_2241 AsmA family protein YP_963631.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_963632.1 KEGG: son:SO2569 hypothetical protein YP_963633.1 PFAM: protein of unknown function DUF885; KEGG: son:SO2570 lipoprotein, putative YP_963634.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO2571 ATP-dependent RNA helicase, DEAD box family YP_963635.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: she:Shewmr4_2169 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_963636.1 PFAM: protein of unknown function UPF0153; KEGG: she:Shewmr4_2170 protein of unknown function UPF0153 YP_963637.1 PFAM: protein of unknown function DUF709; KEGG: son:SO2575 hypothetical protein YP_963638.1 blocks the formation of polar Z-ring septums YP_963639.1 TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: shm:Shewmr7_2251 septum site-determining protein MinD YP_963640.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_963641.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: she:Shewmr4_2176 ribonuclease D YP_963642.1 Activates fatty acids by binding to coenzyme A YP_963643.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: shm:Shewmr7_2255 alpha/beta hydrolase fold YP_963644.1 KEGG: shm:Shewmr7_2256 hypothetical protein YP_963645.1 KEGG: she:Shewmr4_2180 hypothetical protein YP_963646.1 KEGG: shm:Shewmr7_2258 hypothetical protein YP_963647.1 PFAM: peptidase M22, glycoprotease; KEGG: son:SO2586 hypothetical protein YP_963648.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_963649.1 this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae YP_963650.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: shm:Shewmr7_2262 2OG-Fe(II) oxygenase YP_963651.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_963652.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ppr:PBPRB1061 hypothetical protein YP_963653.1 KEGG: shm:Shewmr7_3172 hypothetical protein YP_963654.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: she:Shewmr4_2189 protein tyrosine phosphatase YP_963655.1 catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_963656.1 PFAM: diacylglycerol kinase; KEGG: shm:Shewmr7_2269 diacylglycerol kinase YP_963657.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2202 transcriptional regulator, LysR family YP_963658.1 PFAM: protein of unknown function DUF413; KEGG: she:Shewmr4_2194 protein of unknown function DUF413 YP_963659.1 TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: son:SO2200 ribosomal protein S6 modification protein, putative YP_963660.1 KEGG: shm:Shewmr7_2273 hypothetical protein YP_963661.1 PFAM: peptidase M28; KEGG: she:Shewmr4_2197 peptidase M28 YP_963662.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: she:Shewmr4_2198 diguanylate cyclase YP_963663.1 TIGRFAM: sortase family protein; PFAM: peptidase C60, sortase A and B; KEGG: she:Shewmr4_2199 sortase family protein YP_963664.1 KEGG: shm:Shewmr7_2277 vault protein inter-alpha-trypsin domain protein; TIGRFAM: LPXTG-motif cell wall anchor domain; PFAM: von Willebrand factor, type A; Vault protein inter-alpha-trypsin domain protein; SMART: Vault protein inter-alpha-trypsin, metazoa YP_963665.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO2193 DNA-binding response regulator YP_963666.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: shm:Shewmr7_2280 periplasmic sensor signal transduction histidine kinase YP_963667.1 catalyzes the formation of L-homocysteine from cystathionine YP_963668.1 PFAM: CreA family protein; KEGG: she:Shewmr4_2205 CreA family protein YP_963669.1 KEGG: she:Shewmr4_2206 hypothetical protein YP_963670.1 PFAM: Polyphosphate kinase; KEGG: she:Shewmr4_2207 polyphosphate kinase YP_963671.1 PFAM: Ppx/GppA phosphatase; KEGG: she:Shewmr4_2208 Ppx/GppA phosphatase YP_963672.1 PFAM: major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_1697 major facilitator superfamily MFS_1 YP_963673.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_1621 transcriptional regulator, LysR family YP_963674.1 KEGG: son:SO1913 hypothetical protein YP_963675.1 KEGG: she:Shewmr4_1619 acyl-CoA thioesterase II; TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase YP_963676.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: she:Shewmr4_1618 short-chain dehydrogenase/reductase SDR YP_963677.1 TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; KEGG: son:SO1910 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_963678.1 PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B; KEGG: son:SO1909 hypothetical protein YP_963679.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_1689 transcriptional regulator, LysR family YP_963680.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_963681.1 PFAM: small multidrug resistance protein; KEGG: son:SO1901 sugE protein YP_963682.1 PFAM: AMP-dependent synthetase and ligase; KEGG: she:Shewmr4_2319 AMP-dependent synthetase and ligase YP_963683.1 PFAM: regulatory protein, MerR; KEGG: shm:Shewmr7_2393 transcriptional regulator, MerR family YP_963684.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: son:SO1897 isovaleryl-CoA dehydrogenase YP_963685.1 PFAM: carboxyl transferase; KEGG: she:Shewmr4_2323 propionyl-CoA carboxylase YP_963686.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: son:SO1895 enoyl-CoA hydratase YP_963687.1 PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: son:SO1894 3-methylcrotonyl-CoA carboxylase alpha subunit YP_963688.1 PFAM: pyruvate carboxyltransferase; KEGG: she:Shewmr4_2326 pyruvate carboxyltransferase YP_963689.1 KEGG: son:SO1892 acetate CoA-transferase, subunit A; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_963690.1 KEGG: son:SO1891 3-oxoacid CoA-transferase subunit B; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_963693.1 PFAM: ThiJ/PfpI domain protein; KEGG: son:SO1887 hypothetical protein YP_963694.1 KEGG: shm:Shewmr7_2405 hypothetical protein YP_963695.1 PFAM: protein of unknown function DUF81; KEGG: she:Shewmr4_2333 protein of unknown function DUF81 YP_963696.1 PFAM: glucose sorbosone dehydrogenase; KEGG: ilo:IL2579 glucose dehydrogenase, putative YP_963697.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_2335 GCN5-related N-acetyltransferase YP_963698.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_2409 acriflavin resistance protein YP_963699.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_2410 efflux transporter, RND family, MFP subunit YP_963700.1 PFAM: NlpBDapX family lipoprotein; KEGG: son:SO1880 lipoprotein-34 NlpB YP_963701.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_963702.1 KEGG: son:SO1878 glycine cleavage system transcriptional repressor, putative YP_963703.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_963704.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: son:SO2865 L-lysine exporter, putative YP_963705.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_963706.1 PFAM: protein of unknown function UPF0118; KEGG: shm:Shewmr7_2417 protein of unknown function UPF0118 YP_963707.1 PFAM: SirA family protein; KEGG: shm:Shewmr7_2418 SirA family protein YP_963708.1 PFAM: peptidase M48, Ste24p; Tetratricopeptide TPR_2 repeat protein; KEGG: shm:Shewmr7_2419 peptidase M48, Ste24p YP_963709.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase; KEGG: son:SO2871 arsenate reductase, putative YP_963710.1 KEGG: shm:Shewmr7_2421 hypothetical protein YP_963711.1 KEGG: son:SO2876 hypothetical protein YP_963712.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_963713.1 KEGG: she:Shewmr4_1575 hypothetical protein YP_963714.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: she:Shewmr4_1574 uracil-xanthine permease YP_963715.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: shm:Shewmr7_1648 glutaredoxin-like protein YP_963716.1 PFAM: manganese and iron superoxide dismutase; KEGG: shm:Shewmr7_1647 superoxide dismutase YP_963717.1 PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: shm:Shewmr7_1646 putative serine protein kinase, PrkA YP_963718.1 PFAM: protein of unknown function DUF444; KEGG: shm:Shewmr7_1645 protein of unknown function DUF444 YP_963719.1 PFAM: SpoVR family protein; KEGG: son:SO2884 hypothetical protein YP_963720.1 Multifunctional regulator of fatty acid metabolism YP_963721.1 involved in regulation of intracellular pH under alkaline conditions YP_963722.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_963723.1 KEGG: she:Shewmr4_1565 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein YP_963724.1 activates fatty acids by binding to coenzyme A YP_963725.1 KEGG: son:SO1970 hypothetical protein YP_963726.1 PFAM: protein of unknown function DUF55; KEGG: son:SO1969 hypothetical protein YP_963727.1 KEGG: shm:Shewmr7_2360 hypothetical protein YP_963728.1 KEGG: son:SO1967 hypothetical protein YP_963729.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_2471 TonB-dependent receptor YP_963730.1 PFAM: protein of unknown function DUF124; KEGG: she:Shewmr4_2289 protein of unknown function DUF124 YP_963731.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO1965 transcriptional regulator, LysR family YP_963732.1 PFAM: homogentisate 1,2-dioxygenase; KEGG: shm:Shewmr7_2363 homogentisate 1,2-dioxygenase YP_963733.1 KEGG: son:SO1962 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_963734.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: she:Shewmr4_2295 lysine exporter protein (LysE/YggA) YP_963735.1 PFAM: protein of unknown function DUF482; KEGG: son:SO1953 hypothetical protein YP_963736.1 KEGG: shm:Shewmr7_2369 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_963737.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_2373 GCN5-related N-acetyltransferase YP_963738.1 PFAM: nitroreductase; KEGG: shm:Shewmr7_2374 nitroreductase YP_963739.1 KEGG: son:SO2711 hypothetical protein YP_963740.1 PFAM: aminoglycoside phosphotransferase; KEGG: son:SO2712 hypothetical protein YP_963741.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: shm:Shewmr7_2378 nicotinamide mononucleotide transporter PnuC YP_963742.1 KEGG: son:SO2714 hypothetical protein YP_963743.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO2715 TonB-dependent receptor YP_963744.1 PFAM: cyclic nucleotide-binding; KEGG: son:SO2717 cyclic nucleotide binding protein, putative YP_963745.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO2718 hypothetical protein YP_963746.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_963747.1 KEGG: she:Shewmr4_1960 hypothetical protein YP_963748.1 PFAM: protein of unknown function DUF1425; KEGG: son:SO2720 hypothetical protein YP_963749.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_2383 uncharacterized domain 1 YP_963750.1 PFAM: histidine triad (HIT) protein; KEGG: shm:Shewmr7_2384 histidine triad (HIT) protein YP_963751.1 PFAM: peptidase M61 domain protein; KEGG: shm:Shewmr7_2385 peptidase M61 domain protein YP_963752.1 KEGG: shm:Shewmr7_1637 hypothetical protein YP_963753.1 PFAM: YceI family protein; KEGG: shm:Shewmr7_1636 YceI family protein YP_963754.1 PFAM: protein of unknown function DUF188; KEGG: she:Shewmr4_1560 protein of unknown function DUF188 YP_963755.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_963756.1 PFAM: S-adenosylmethionine decarboxylase; KEGG: son:SO1871 S-adenosylmethionine decarboxylase proenzyme, putative YP_963757.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_963758.1 KEGG: she:Shewmr4_1555 hypothetical protein YP_963759.1 PFAM: protein of unknown function DUF480; KEGG: son:SO1867 hypothetical protein YP_963760.1 KEGG: son:SO1866 hypothetical protein YP_963761.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1865 ABC transporter, ATP-binding protein YP_963762.1 KEGG: she:Shewmr4_1549 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_963763.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_963764.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_963765.1 KEGG: shm:Shewmr7_1613 conserved hypothetical ATP-dependent protease YP_963766.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_963767.1 PFAM: ribosome modulation factor; KEGG: shm:Shewmr7_1611 ribosome modulation factor YP_963768.1 KEGG: shm:Shewmr7_1610 hypothetical protein YP_963769.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_963770.1 PFAM: glutaredoxin; glutaredoxin 2; KEGG: she:Shewmr4_1541 glutaredoxin 2 YP_963771.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_963772.1 PFAM: heat shock protein DnaJ domain protein; KEGG: son:SO1850 DnaJ domain protein YP_963773.1 KEGG: son:SO1849 hypothetical protein YP_963774.1 KEGG: she:Shewmr4_1537 hypothetical protein YP_963775.1 KEGG: shm:Shewmr7_1603 hypothetical protein YP_963776.1 KEGG: son:SO1845 hypothetical protein YP_963777.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); KEGG: ava:Ava_3254 RNA-directed DNA polymerase (reverse transcriptase) YP_963778.1 PFAM: PKD domain containing protein; Endonuclease/exonuclease/phosphatase; KEGG: son:SO1844 extracellular nuclease, putative YP_963779.1 KEGG: shm:Shewmr7_1600 hypothetical protein YP_963780.1 KEGG: shm:Shewmr7_1599 hypothetical protein YP_963781.1 KEGG: son:SO1840 hypothetical protein YP_963782.1 KEGG: son:SO1839 hypothetical protein YP_963783.1 KEGG: shm:Shewmr7_1597 hypothetical protein YP_963784.1 KEGG: shm:Shewmr7_1596 hypothetical protein YP_963785.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_1595 GCN5-related N-acetyltransferase YP_963786.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_1594 GCN5-related N-acetyltransferase YP_963787.1 SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: shm:Shewmr7_1593 prolyl 4-hydroxylase, alpha subunit YP_963788.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: shm:Shewmr7_1592 peptidyl-dipeptidase DCP YP_963789.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_963790.1 KEGG: shm:Shewmr7_1590 hypothetical protein YP_963791.1 TIGRFAM: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_2438 hypothetical protein YP_963792.1 TIGRFAM: OmpA domain protein; PFAM: OmpA/MotB domain protein; KEGG: shm:Shewmr7_2439 OmpA/MotB domain protein YP_963793.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_963794.1 PFAM: TolA family protein; KEGG: she:Shewmr4_2369 TolA family protein YP_963795.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: she:Shewmr4_2370 biopolymer transport protein ExbD/TolR YP_963796.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: shm:Shewmr7_2443 MotA/TolQ/ExbB proton channel YP_963797.1 TIGRFAM: 4-hydroxybenzoyl-CoA thioesterase; PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_2444 4-hydroxybenzoyl-CoA thioesterase YP_963798.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller; KEGG: shm:Shewmr7_2445 prolyl oligopeptidase YP_963799.1 PFAM: OmpA/MotB domain protein; KEGG: she:Shewmr4_2374 OmpA/MotB domain protein YP_963800.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_963801.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shm:Shewmr7_2448 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_963802.1 PFAM: Gluconate transporter; Na+/H+ antiporter NhaC; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: son:SO2757 membrane protein, putative YP_963803.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_963804.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_963805.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_963806.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO2762 nagD protein YP_963807.1 PFAM: peptidase M28; KEGG: shm:Shewmr7_2455 peptidase M28 YP_963808.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_963809.1 PFAM: Patatin; KEGG: sfr:Sfri_0718 patatin YP_963810.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_2386 TonB-dependent siderophore receptor YP_963811.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: she:Shewmr4_2387 acyl-CoA dehydrogenase domain protein YP_963812.1 PFAM: Aldose 1-epimerase; KEGG: shm:Shewmr7_2460 aldose 1-epimerase YP_963813.1 PFAM: oxidoreductase domain protein; NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: she:Shewmr4_2391 6-phosphogluconate dehydrogenase, NAD-binding YP_963814.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_2462 thioesterase superfamily protein YP_963815.1 KEGG: shm:Shewmr7_2463 hypothetical protein YP_963816.1 PFAM: beta-ketoacyl synthase; KEGG: son:SO2774 3-oxoacyl-(acyl-carrier-protein) synthase II YP_963817.1 carries the fatty acid chain in fatty acid biosynthesis YP_963818.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: son:SO2776 3-oxoacyl-[acyl-carrier protein] reductase YP_963819.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein; KEGG: shm:Shewmr7_2467 malonyl CoA-acyl carrier protein transacylase YP_963820.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_963821.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_963822.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_963823.1 PFAM: protein of unknown function DUF177; KEGG: shm:Shewmr7_2471 protein of unknown function DUF177 YP_963824.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: son:SO2782 maf protein, putative YP_963825.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: she:Shewmr4_2403 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_963826.1 KEGG: shm:Shewmr7_2474 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_963827.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: she:Shewmr4_2405 ribonuclease, Rne/Rng family YP_963828.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: shm:Shewmr7_2477 cold-shock DNA-binding domain protein YP_963829.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_963830.1 KEGG: son:SO2789 hypothetical protein YP_963831.1 KEGG: son:SO2938 hypothetical protein YP_963832.1 KEGG: son:SO2939 hypothetical protein YP_963834.1 PFAM: Carbohydrate-binding family V/XII; Fibronectin, type III domain protein; KEGG: son:SO2940 prophage LambdaSo, host specificity protein J, putative YP_963835.1 PFAM: bacteriophage lambda tail assembly I; KEGG: son:SO2941 prophage LambdaSo, tail assembly protein I YP_963836.1 KEGG: sec:SC2612 hypothetical protein YP_963837.1 KEGG: ecs:ECs1200 DNA-binding protein YP_963838.1 PFAM: Arc domain protein DNA binding domain protein; KEGG: pau:PA14_20290 DNA binding-protein YP_963839.1 KEGG: dvu:DVU0290 lipoprotein, putative YP_963840.1 PFAM: NLP/P60 protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: son:SO2948 prophage LambdaSo, tail assembly protein K, putative YP_963841.1 PFAM: phage minor tail protein L; KEGG: son:SO2949 prophage LambdaSo, minor tail protein L YP_963843.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); KEGG: ana:alr3497 hypothetical protein YP_963844.1 KEGG: par:Psyc_0448 hypothetical protein YP_963846.1 PFAM: phage minor tail family protein; KEGG: son:SO2952 prophage LambdaSo, minor tail protein M, putative YP_963848.1 TIGRFAM: phage tail tape measure protein, lambda family; PFAM: Prophage tail length tape measure; KEGG: son:SO2953 prophage LambdaSo, tail length tape meausure protein YP_963849.1 KEGG: son:SO2954 hypothetical protein YP_963850.1 KEGG: son:SO2955 hypothetical protein YP_963851.1 KEGG: son:SO2956 prophage LambdaSo, major tail protein V, putative YP_963852.1 KEGG: son:SO2957 hypothetical protein YP_963853.1 TIGRFAM: phage protein, HK97 gp10 family; PFAM: TP901-1 ORF40 family protein; KEGG: son:SO2958 hypothetical protein YP_963854.1 PFAM: phage head-tail adaptor, putative; KEGG: son:SO2960 hypothetical protein YP_963855.1 KEGG: son:SO2961 hypothetical protein YP_963856.1 KEGG: son:SO2962 hypothetical protein YP_963857.1 TIGRFAM: phage major capsid protein, HK97 family; PFAM: phage major capsid protein, HK97; KEGG: son:SO2963 prophage LambdaSo, major capsid protein, HK97 family YP_963858.1 PFAM: peptidase S14, ClpP; KEGG: son:SO2964 ClpP protease family protein YP_963859.1 TIGRFAM: phage portal protein, HK97 family; PFAM: phage portal protein; KEGG: son:SO2965 prophage LambdaSo, portal protein, HK97 family YP_963860.1 KEGG: son:SO2966 hypothetical protein YP_963861.1 PFAM: phage Terminase; KEGG: son:SO2967 hypothetical phage terminase large subunit YP_963862.1 TIGRFAM: phage terminase, small subunit, putative, P27 family; PFAM: phage terminase, small subunit, putative, P27; KEGG: son:SO2968 hypothetical phage terminase, small subunit YP_963863.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: son:SO2969 prophage LambdaSo, holin, putative YP_963864.1 KEGG: son:SO2970 hypothetical protein YP_963865.1 KEGG: son:SO2971 hypothetical protein YP_963866.1 KEGG: son:SO2972 hypothetical protein YP_963867.1 KEGG: son:SO2973 prophage LambdaSo, lysozyme, putative YP_963868.1 KEGG: shm:Shewmr7_0731 hypothetical protein YP_963870.1 KEGG: son:SO2976 hypothetical protein YP_963873.1 PFAM: phage integrase family protein; KEGG: son:SO2978 prophage LambdaSo, site-specific recombinase, phage integrase family YP_963874.1 KEGG: son:SO2979 hypothetical protein YP_963875.1 TIGRFAM: uncharacterized phage protein; KEGG: son:SO2980 hypothetical protein YP_963876.1 KEGG: son:SO2981 hypothetical protein YP_963877.1 KEGG: son:SO2982 hypothetical protein YP_963878.1 KEGG: son:SO2983 hypothetical protein YP_963879.1 KEGG: son:SO2984 hypothetical protein YP_963880.1 TIGRFAM: phage replication protein O; PFAM: phage replication protein O domain protein; KEGG: son:SO2985 prophage LambdaSo, replication protein O YP_963881.1 KEGG: son:SO2986 hypothetical protein YP_963882.1 KEGG: son:SO2987 hypothetical protein YP_963883.1 KEGG: son:SO2988 hypothetical protein YP_963884.1 PFAM: helix-turn-helix domain protein; KEGG: son:SO2989 prophage LambdaSo, transcriptional regulator, Cro/CI family YP_963885.1 PFAM: helix-turn-helix domain protein; peptidase S24, S26A and S26B; KEGG: pst:PSPTO_0571 repressor protein C2 YP_963886.1 KEGG: son:SO2991 hypothetical protein YP_963887.1 KEGG: sth:STH1713 ATP-dependent DNA helicase; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_963888.1 PFAM: bacteriophage lambda tail assembly I; KEGG: son:SO2941 prophage LambdaSo, tail assembly protein I YP_963890.1 KEGG: son:SO2997 hypothetical protein YP_963891.1 KEGG: son:SO2998 hypothetical protein YP_963892.1 KEGG: sdn:Sden_3274 hypothetical protein YP_963893.1 KEGG: ecs:ECs4955 hypothetical protein YP_963895.1 KEGG: son:SO2999 hypothetical protein YP_963896.1 KEGG: son:SO3000 hypothetical protein YP_963897.1 KEGG: psb:Psyr_2841 hypothetical protein YP_963898.1 KEGG: son:SO3003 hypothetical protein YP_963900.1 PFAM: DNA N-6-adenine-methyltransferase; KEGG: eci:UTI89_C1294 putative DNA N-6-adenine-methyltransferase of bacteriophage YP_963901.1 PFAM: C-5 cytosine-specific DNA methylase; KEGG: son:SO3006 prophage LambdaSo, type II DNA modification methyltransferase, putative YP_963902.1 KEGG: bce:BC1874 phage protein YP_963903.1 KEGG: pat:Patl_0687 hypothetical protein YP_963904.1 KEGG: son:SO3007 hypothetical protein YP_963906.1 KEGG: pst:PSPTO_3428 hypothetical protein YP_963907.1 PFAM: phage integrase family protein; KEGG: sfr:Sfri_1639 phage integrase family protein YP_963908.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_963909.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_963910.1 PFAM: protein of unknown function DUF1289; KEGG: son:SO2792 hypothetical protein YP_963911.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: she:Shewmr4_2413 glyoxalase/bleomycin resistance protein/dioxygenase YP_963912.1 KEGG: she:Shewmr4_2414 hypothetical protein YP_963913.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: son:SO2795 glyoxalase family protein YP_963914.1 PFAM: protein of unknown function DUF748; KEGG: she:Shewmr4_2416 protein of unknown function DUF748 YP_963915.1 PFAM: glutaredoxin; Glutathione S-transferase, N-terminal domain; KEGG: shm:Shewmr7_2487 glutaredoxin YP_963916.1 KEGG: she:Shewmr4_2418 hypothetical protein YP_963917.1 KEGG: son:SO2799 lipoprotein, putative YP_963918.1 PFAM: protein of unknown function DUF343; KEGG: son:SO2800 hypothetical protein YP_963919.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_963920.1 KEGG: son:SO2802 ABC transporter, ATP-binding protein MsbA; TIGRFAM: lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_963921.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG: shm:Shewmr7_2493 DNA internalization-related competence protein ComEC/Rec2 YP_963922.1 KEGG: shm:Shewmr7_2494 hypothetical protein YP_963923.1 PFAM: phosphate-starvation-inducible E; KEGG: shm:Shewmr7_2496 phosphate-starvation-inducible E YP_963924.1 PFAM: type IV pilus assembly PilZ; KEGG: shm:Shewmr7_2497 type IV pilus assembly PilZ YP_963925.1 KEGG: son:SO2808 hypothetical protein YP_963926.1 KEGG: shm:Shewmr7_2499 RepA domain protein YP_963927.1 KEGG: shm:Shewmr7_2500 hypothetical protein YP_963928.1 PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type, transmembrane region; KEGG: son:SO2822 sensor histidine kinase YP_963929.1 unknown function; when overproduced it confers drug-resistance YP_963930.1 PFAM: carbon starvation protein CstA; KEGG: she:Shewmr4_2433 carbon starvation protein CstA YP_963931.1 KEGG: she:Shewmr4_2434 hypothetical protein YP_963932.1 KEGG: son:SO2829 hypothetical protein YP_963933.1 KEGG: son:SO2830 hypothetical protein YP_963934.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_963935.1 KEGG: she:Shewmr4_2439 hypothetical protein YP_963936.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_963937.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_963938.1 KEGG: shm:Shewmr7_2512 hypothetical protein YP_963939.1 PFAM: Patatin; KEGG: son:SO2836 hypothetical protein YP_963940.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: she:Shewmr4_2444 DEAD/DEAH box helicase domain protein YP_963941.1 KEGG: son:SO2839 hypothetical protein YP_963942.1 PFAM: protein of unknown function DUF45; KEGG: son:SO2840 hypothetical protein YP_963943.1 KEGG: son:SO2841 hypothetical protein YP_963944.1 PFAM: peptidase M23B; Opacity-associated protein A; KEGG: shm:Shewmr7_2518 peptidase M23B YP_963945.1 PFAM: SMC domain protein; KEGG: she:Shewmr4_2449 SMC domain protein YP_963946.1 TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase; KEGG: shm:Shewmr7_2520 nuclease SbcCD, D subunit YP_963947.1 PFAM: protein of unknown function DUF81; KEGG: son:SO2846 hypothetical protein YP_963948.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2522 transcriptional regulator, LysR family YP_963949.1 KEGG: plu:plu4649 transposase, IS4 family YP_963950.1 PFAM: protein of unknown function DUF1260; KEGG: son:SO1836 hypothetical protein YP_963951.1 KEGG: shm:Shewmr7_2524 RNA-binding S4 domain protein YP_963952.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1834 acetyltransferase, GNAT family YP_963953.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: shm:Shewmr7_2526 PpiC-type peptidyl-prolyl cis-trans isomerase YP_963954.1 PFAM: protein of unknown function DUF885; KEGG: she:Shewmr4_2457 protein of unknown function DUF885 YP_963955.1 PFAM: GGDEF domain containing protein; KEGG: son:SO1830 GGDEF domain protein YP_963956.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_2529 TPR repeat-containing protein YP_963957.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: shm:Shewmr7_2530 TonB family protein YP_963958.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: shm:Shewmr7_2531 biopolymer transport protein ExbD/TolR YP_963959.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: she:Shewmr4_2462 MotA/TolQ/ExbB proton channel YP_963960.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: shm:Shewmr7_2533 MotA/TolQ/ExbB proton channel YP_963961.1 KEGG: shm:Shewmr7_2534 hypothetical protein YP_963962.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pha:PSHAb0158 putative TonB-dependent receptor with TonB-box YP_963963.1 PFAM: porin, Gram-negative type; KEGG: she:Shewmr4_2468 porin, gram-negative type YP_963964.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_963965.1 helicase involved in DNA repair and perhaps also replication YP_963966.1 PFAM: protein of unknown function DUF81; KEGG: shm:Shewmr7_2539 protein of unknown function DUF81 YP_963967.1 KEGG: she:Shewmr4_2472 primosomal replication protein N'', putative YP_963968.1 KEGG: she:Shewmr4_2473 hypothetical protein YP_963969.1 KEGG: son:SO1814 hypothetical protein YP_963970.1 KEGG: shm:Shewmr7_2544 competence protein ComEA helix-hairpin-helix repeat protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding, class 1 YP_963971.1 KEGG: she:Shewmr4_2477 methionine gamma-lyase; TIGRFAM: methionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_963972.1 PFAM: conserved hypothetical protein 1620; KEGG: she:Shewmr4_2478 conserved hypothetical protein 1620 YP_963973.1 PFAM: protein of unknown function DUF463, YcjX family protein; KEGG: she:Shewmr4_2479 protein of unknown function DUF463, YcjX family protein YP_963974.1 PFAM: PspC domain protein; KEGG: shm:Shewmr7_2548 phage shock protein C, PspC YP_963975.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_963976.1 PFAM: PspA/IM30 family protein; KEGG: son:SO1807 phage shock protein A YP_963977.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_2551 transcriptional regulator, fis family YP_963978.1 PFAM: extracellular solute-binding protein, family 5; KEGG: shm:Shewmr7_2552 extracellular solute-binding protein, family 5 YP_963979.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: she:Shewmr4_2485 binding-protein-dependent transport systems inner membrane component YP_963980.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2554 binding-protein-dependent transport systems inner membrane component YP_963981.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; KEGG: shm:Shewmr7_2555 oligopeptide/dipeptide ABC transporter, ATPase subunit YP_963982.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1801 peptide ABC transporter, ATP-binding protein YP_963983.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_963984.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: she:Shewmr4_2491 PpiC-type peptidyl-prolyl cis-trans isomerase YP_963985.1 PFAM: histone family protein DNA-binding protein; KEGG: shm:Shewmr7_2560 histone family protein DNA-binding protein YP_963986.1 KEGG: shm:Shewmr7_2561 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16, lon domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_963987.1 binds and unfolds substrates as part of the ClpXP protease YP_963988.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_963989.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_963990.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_963991.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_963992.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: son:SO1790 peptidyl-prolyl cis-trans isomerase B YP_963993.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_963994.1 PFAM: tRNA--hydroxylase; KEGG: she:Shewmr4_2501 tRNA--hydroxylase YP_963995.1 PFAM: protein of unknown function DUF1282; KEGG: she:Shewmr4_2502 protein of unknown function DUF1282 YP_963996.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_963997.1 TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; nucleoside recognition domain protein; Miro domain protein; KEGG: son:SO1784 ferrous iron transport protein B YP_963998.1 PFAM: FeoA family protein; KEGG: shm:Shewmr7_2573 FeoA family protein YP_963999.1 KEGG: son:SO1779 decaheme cytochrome c YP_964000.1 KEGG: shm:Shewmr7_2578 decaheme cytochrome c YP_964001.1 TIGRFAM: cytochrome C family protein; KEGG: son:SO1777 decaheme cytochrome c MtrA YP_964002.1 KEGG: she:Shewmr4_2512 outer membrane protein precursor MtrB YP_964003.1 KEGG: she:Shewmr4_2513 hypothetical protein YP_964004.1 KEGG: shm:Shewmr7_2582 phage SPO1 DNA polymerase domain protein YP_964005.1 PFAM: sugar diacid recognition domain protein; KEGG: shm:Shewmr7_2584 transcriptional regulator, CdaR YP_964006.1 PFAM: Catalase domain protein; KEGG: she:Shewmr4_2517 catalase domain protein YP_964007.1 PFAM: Gluconate transporter; Citrate transporter; KEGG: shm:Shewmr7_2586 gluconate transporter YP_964008.1 PFAM: glycerate kinase; KEGG: shm:Shewmr7_2587 glycerate kinase YP_964009.1 PFAM: Pyridoxal-dependent decarboxylase; KEGG: she:Shewmr4_2520 pyridoxal-dependent decarboxylase YP_964010.1 PFAM: transposase, mutator type; KEGG: son:SO4497 ISSod5, transposase YP_964011.1 KEGG: she:Shewmr4_1779 transposase IS116/IS110/IS902 family protein YP_964012.1 KEGG: she:Shewmr4_2525 hypothetical protein YP_964014.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: she:Shewmr4_1779 transposase IS116/IS110/IS902 family protein YP_964015.1 KEGG: cps:CPS_2655 hypothetical protein YP_964016.1 KEGG: son:SO1765 hypothetical protein YP_964017.1 PFAM: protein of unknown function DUF1706; KEGG: son:SO1764 hypothetical protein YP_964018.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: son:SO1763 streptogramin A acetyl transferase YP_964019.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: son:SO1762 transcriptional regulator, AraC/XylS family YP_964020.1 PFAM: AzlC family protein; KEGG: she:Shewmr4_2528 AzlC family protein YP_964021.1 PFAM: branched-chain amino acid transport; KEGG: son:SO1759 hypothetical protein YP_964022.1 PFAM: Helix-turn-helix, type 11 domain protein; KEGG: she:Shewmr4_2538 helix-turn-helix, type 11 domain protein YP_964023.1 PFAM: transcription activator, effector binding; KEGG: son:SO1757 hypothetical protein YP_964024.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: shm:Shewmr7_2607 glyoxalase/bleomycin resistance protein/dioxygenase YP_964025.1 PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: she:Shewmr4_2541 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I YP_964026.1 PFAM: Integral membrane protein TerC; KEGG: son:SO1747 membrane protein, putative YP_964027.1 KEGG: shm:Shewmr7_2611 hypothetical protein YP_964028.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility C-terminal domain; KEGG: shm:Shewmr7_2612 3-beta hydroxysteroid dehydrogenase/isomerase YP_964029.1 Catalyzes the specific recognition and activation of amino acids during peptide synthesis YP_964030.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO1743 hydrolase, alpha/beta hydrolase fold family YP_964031.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_964032.1 KEGG: son:SO1741 hypothetical protein YP_964033.1 PFAM: protein of unknown function DUF1289; KEGG: shm:Shewmr7_2617 protein of unknown function DUF1289 YP_964034.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: son:SO1738 hypothetical protein YP_964035.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: she:Shewmr4_2552 choline/carnitine/betaine transporter YP_964036.1 KEGG: son:SO1736 hypothetical protein YP_964037.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: son:SO1734 glyoxalase family protein YP_964038.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: ilo:IL0610 methyl-accepting chemotaxis protein (contains HAMP domain) YP_964039.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_964040.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_964041.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: she:Shewmr4_2559 phosphate ABC transporter, inner membrane subunit PstA YP_964042.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2627 binding-protein-dependent transport systems inner membrane component YP_964043.1 PFAM: amino acid-binding ACT domain protein; KEGG: son:SO1722 ACT domain protein YP_964044.1 KEGG: shm:Shewmr7_2631 hypothetical protein YP_964046.1 KEGG: shm:Shewmr7_2632 hypothetical protein YP_964047.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shm:Shewmr7_2634 lysine exporter protein (LysE/YggA) YP_964048.1 PFAM: protein of unknown function DUF1415; KEGG: shm:Shewmr7_2635 protein of unknown function DUF1415 YP_964050.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: ppu:PP_5020 methyl-accepting chemotaxis transducer YP_964051.1 KEGG: son:SO1711 hypothetical protein YP_964052.1 KEGG: son:SO1710 hypothetical protein YP_964053.1 PFAM: acetyl-CoA hydrolase/transferase; KEGG: son:SO1708 4-hydroxybutyrate coenzyme A transferase YP_964054.1 PFAM: ABC-2 type transporter; KEGG: shm:Shewmr7_2640 ABC-2 type transporter YP_964055.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: she:Shewmr4_2574 ABC transporter related YP_964056.1 PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_2575 secretion protein HlyD family protein YP_964057.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_2643 transcriptional regulator, TetR family YP_964058.1 KEGG: shm:Shewmr7_2644 hypothetical protein YP_964059.1 PFAM: transcriptional regulator domain protein; Tetratricopeptide TPR_2 repeat protein; KEGG: shm:Shewmr7_2647 transcriptional regulator, CadC YP_964060.1 KEGG: she:Shewmr4_2581 hypothetical protein YP_964061.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: son:SO4548 transposase, IS110 family YP_964062.1 KEGG: shm:Shewmr7_1178 protein of unknown function DUF1568 YP_964063.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: she:Shewmr4_2582 diguanylate cyclase YP_964064.1 PFAM: FAD linked oxidase domain protein; Berberine/berberine domain protein; KEGG: shm:Shewmr7_2650 FAD linked oxidase domain protein YP_964065.1 PFAM: Lipocalin-related protein and Bos/Can/Equ allergen; Lipocalin family protein; KEGG: son:SO1691 lipoprotein Blc YP_964066.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1690 ABC transporter, ATP-binding protein YP_964067.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: she:Shewmr4_2587 copper-translocating P-type ATPase YP_964068.1 PFAM: regulatory protein, MerR; KEGG: she:Shewmr4_2588 transcriptional regulator, MerR family YP_964069.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; KEGG: she:Shewmr4_2589 peptidase S9, prolyl oligopeptidase active site domain protein YP_964070.1 KEGG: shm:Shewmr7_2657 hypothetical protein YP_964071.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_964072.1 KEGG: shm:Shewmr7_2659 3-hydroxyisobutyrate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding YP_964073.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: shm:Shewmr7_2660 enoyl-CoA hydratase/isomerase YP_964074.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_964075.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: shm:Shewmr7_2662 acyl-CoA dehydrogenase domain protein YP_964076.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: she:Shewmr4_2596 methylmalonate-semialdehyde dehydrogenase YP_964077.1 KEGG: she:Shewmr4_2597 acetyl-CoA acetyltransferases; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase YP_964078.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: vch:VCA0220 hemolysin secretion protein HylB YP_964079.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_964080.1 KEGG: shm:Shewmr7_2666 hypothetical protein YP_964081.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: son:SO1674 short chain dehydrogenase family protein YP_964082.1 receptor for colicin S4 YP_964083.1 PFAM: protein of unknown function DUF925; KEGG: she:Shewmr4_2602 protein of unknown function DUF925 YP_964084.1 TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: son:SO1671 glutathione S-transferase family protein YP_964085.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: son:SO1670 fumarylacetoacetate hydrolase family protein YP_964086.1 PFAM: sigma-54 factor, interaction domain-containing protein; amino acid-binding ACT domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_2672 transcriptional regulator, TyrR YP_964087.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_964088.1 phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin YP_964089.1 KEGG: shm:Shewmr7_2675 UTP-glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase YP_964090.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: she:Shewmr4_2609 UDP-glucose 4-epimerase YP_964091.1 TIGRFAM: ferredoxin-type protein NapF; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_2677 ferredoxin-type protein NapF YP_964092.1 PFAM: protein of unknown function DUF583; KEGG: shm:Shewmr7_2678 protein of unknown function DUF583 YP_964093.1 PFAM: regulatory protein, LysR; KEGG: son:SO1661 transcriptional regulator, LysR family YP_964094.1 KEGG: son:SO1659 decaheme cytochrome c YP_964097.1 TIGRFAM: YD repeat protein; KEGG: shm:Shewmr7_1124 YD repeat protein YP_964099.1 TIGRFAM: YD repeat protein; PFAM: Fibronectin, type III domain protein; YD repeat-containing protein; FG-GAP repeat protein; KEGG: shm:Shewmr7_1124 YD repeat protein YP_964100.1 PFAM: phage integrase family protein; KEGG: shm:Shewmr7_3899 phage integrase family protein YP_964101.1 KEGG: shm:Shewmr7_2681 hypothetical protein YP_964102.1 PFAM: protein of unknown function DUF218; KEGG: son:SO1657 hypothetical protein YP_964103.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_964104.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: shm:Shewmr7_2684 3'(2'),5'-bisphosphate nucleotidase YP_964105.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; KEGG: she:Shewmr4_2619 PHP C-terminal domain protein YP_964106.1 PFAM: SNF2-related protein; helicase domain protein; zinc finger, SWIM domain protein; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_2687 SNF2-related protein YP_964107.1 PFAM: protein of unknown function DUF885; KEGG: she:Shewmr4_2621 protein of unknown function DUF885 YP_964108.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: shm:Shewmr7_2689 cold-shock DNA-binding domain protein YP_964109.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO1646 GGDEF family protein YP_964110.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; KEGG: she:Shewmr4_2625 tRNA(Ile)-lysidine synthetase YP_964111.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_964112.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_964113.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_964114.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_964115.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_964116.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_964117.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: shm:Shewmr7_2699 outer membrane chaperone Skp (OmpH) YP_964118.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: shm:Shewmr7_2700 surface antigen (D15) YP_964119.1 TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: shm:Shewmr7_2701 putative membrane-associated zinc metalloprotease YP_964120.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_964121.1 PFAM: phosphatidate cytidylyltransferase; KEGG: shm:Shewmr7_2703 phosphatidate cytidylyltransferase YP_964122.1 KEGG: son:SO1633 undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_964123.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_964124.1 Catalyzes the phosphorylation of UMP to UDP YP_964125.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_964126.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_964127.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_964128.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_964129.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_964130.1 KEGG: shm:Shewmr7_2713 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: CBS domain containing protein; GAF domain protein; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_964131.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_964132.1 TIGRFAM: PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS, EIIB protein; phosphotransferase system, EIIC; KEGG: shm:Shewmr7_2715 PTS system, glucose-like IIB subunint YP_964133.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_964135.1 PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_2717 pseudouridylate synthase YP_964136.1 PFAM: protein of unknown function DUF446; KEGG: shm:Shewmr7_2718 protein of unknown function DUF446 YP_964137.1 KEGG: she:Shewmr4_2652 hypothetical protein YP_964138.1 KEGG: son:SO1617 hypothetical protein YP_964139.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1614 acetyltransferase, GNAT family YP_964140.1 KEGG: son:SO1613 hypothetical protein YP_964141.1 KEGG: shm:Shewmr7_2724 hypothetical protein YP_964142.1 KEGG: shm:Shewmr7_2725 hypothetical protein YP_964143.1 KEGG: son:SO1610 hypothetical protein YP_964144.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_964145.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_964146.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: shm:Shewmr7_2731 4'-phosphopantetheinyl transferase YP_964147.1 KEGG: shm:Shewmr7_2732 transcriptional regulator, putative YP_964148.1 PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_2733 beta-ketoacyl synthase YP_964149.1 KEGG: shm:Shewmr7_2734 omega-3 polyunsaturated fatty acid synthase PfaB YP_964150.1 PFAM: beta-ketoacyl synthase; Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; KEGG: she:Shewmr4_2668 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ YP_964151.1 KEGG: shm:Shewmr7_2736 2-nitropropane dioxygenase, NPD YP_964152.1 PFAM: protein of unknown function DUF1328; KEGG: shm:Shewmr7_2739 protein of unknown function DUF1328 YP_964153.1 KEGG: shm:Shewmr7_2740 hypothetical protein YP_964154.1 PFAM: Dual specificity protein phosphatase; diacylglycerol kinase, catalytic region; KEGG: she:Shewmr4_2673 dual specificity protein phosphatase YP_964155.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_2742 sigma54 specific transcriptional regulator, fis family YP_964156.1 KEGG: shm:Shewmr7_2743 hypothetical protein YP_964157.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria; KEGG: shm:Shewmr7_2744 transport-associated YP_964158.1 KEGG: son:SO1589 hypothetical protein YP_964159.1 KEGG: she:Shewmr4_2686 hypothetical protein YP_964160.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: son:SO1585 fumarylacetoacetate hydrolase family protein YP_964161.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: sdn:Sden_2638 chemotaxis sensory transducer YP_964162.1 PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: son:SO1583 hypothetical protein YP_964163.1 PFAM: regulatory protein, MarR; KEGG: shm:Shewmr7_2759 transcriptional regulator, MarR family YP_964164.1 PFAM: major facilitator superfamily MFS_1; KEGG: pau:PA14_03550 putative MFS transporter YP_964165.1 PFAM: PhnA protein-like; SMART: PhnA protein N-terminal, proteobacterial; KEGG: son:SO1581 PhnA protein YP_964166.1 TIGRFAM: TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO1580 TonB-dependent heme receptor YP_964167.1 KEGG: she:Shewmr4_2693 hypothetical protein YP_964168.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: shm:Shewmr7_2764 glutathione S-transferase, N-terminal domain protein YP_964169.1 PFAM: Fmu (Sun) domain protein; KEGG: son:SO1575 NOL1/NOP2/sun family putative RNA methylase YP_964170.1 KEGG: she:Shewmr4_2698 hypothetical protein YP_964171.1 PFAM: YfaZ family protein; KEGG: she:Shewmr4_2702 YfaZ family protein YP_964172.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_2703 GCN5-related N-acetyltransferase YP_964173.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: she:Shewmr4_2704 MgtE intracellular region YP_964174.1 PFAM: glutathione peroxidase; KEGG: she:Shewmr4_2705 glutathione peroxidase YP_964175.1 PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: son:SO1561 peptidase, M1 family YP_964176.1 TIGRFAM: phosphate binding protein; KEGG: she:Shewmr4_2707 phosphate binding protein YP_964177.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: son:SO1559 phosphate regulon sensor protein PhoR YP_964178.1 TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_2777 two component transcriptional regulator, winged helix family YP_964179.1 PFAM: porin, Gram-negative type; KEGG: son:SO1557 outer membrane porin, putative YP_964180.1 Required for efficient pilin antigenic variation YP_964181.1 PFAM: peptidase M61 domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: she:Shewmr4_2712 peptidase M61 domain protein YP_964182.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_2781 TPR repeat-containing protein YP_964183.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_2782 diguanylate cyclase YP_964184.1 PFAM: conserved hypothetical protein 730; KEGG: shm:Shewmr7_2783 conserved hypothetical protein 730 YP_964185.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_964186.1 KEGG: she:Shewmr4_2717 hypothetical protein YP_964187.1 PFAM: transposase IS66; KEGG: pha:PSHAa0410 transposase YP_964188.1 PFAM: IS66 Orf2 family protein; KEGG: pha:PSHAa0409 hypothetical protein YP_964190.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; KEGG: she:Shewmr4_2719 peptidase S9, prolyl oligopeptidase active site domain protein YP_964191.1 catalyzes the formation of 2-oxoglutarate from isocitrate YP_964192.1 KEGG: son:SO1536 hypothetical protein YP_964193.1 PFAM: protein of unknown function DUF423; KEGG: son:SO1535 hypothetical protein YP_964194.1 KEGG: shm:Shewmr7_2794 hypothetical protein YP_964195.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_964196.1 KEGG: shm:Shewmr7_2796 hypothetical protein YP_964197.1 Required for the synthesis of the thiazole moiety YP_964198.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; Vibrio parahaemolyticus protein is associated with the polar flagella YP_964199.1 Homologous to MotA in E. coli and Salmonella. With PomB forms the ion channels that couple flagellar rotation to sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. YP_964200.1 TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII, small subunit; KEGG: shm:Shewmr7_2802 exodeoxyribonuclease VII, small subunit YP_964201.1 PFAM: Polyprenyl synthetase; KEGG: son:SO1526 geranyltranstransferase YP_964202.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_964203.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_964204.1 catalyzes the phosphorylation of NAD to NADP YP_964205.1 PFAM: L-lactate permease; KEGG: son:SO1522 L-lactate permease, putative YP_964206.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; FAD linked oxidase domain protein; KEGG: son:SO1521 iron-sulfur cluster-binding protein YP_964207.1 PFAM: protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: she:Shewmr4_2736 protein of unknown function DUF224, cysteine-rich region domain protein YP_964208.1 KEGG: shm:Shewmr7_2810 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_964209.1 PFAM: protein of unknown function DUF162; KEGG: she:Shewmr4_2738 protein of unknown function DUF162 YP_964210.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_2812 AAA ATPase, central domain protein YP_964214.1 KEGG: she:Shewmr4_1443 hypothetical protein YP_964215.1 KEGG: shm:Shewmr7_2824 hypothetical protein YP_964216.1 PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO1506 MATE efflux family protein YP_964217.1 PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_2748 major facilitator superfamily MFS_1 YP_964218.1 KEGG: son:SO1504 hypothetical protein YP_964219.1 SMART: extracellular solute-binding protein, family 3; KEGG: son:SO1503 ABC transporter, periplasmic substrate-binding protein, putative YP_964220.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein; KEGG: son:SO1502 cobalamin synthesis protein/P47K family protein YP_964221.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO1501 ATP-dependent RNA helicase, DEAD box family YP_964222.1 KEGG: shm:Shewmr7_2831 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; 5TM Receptors of the LytS-YhcK type, transmembrane region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_964223.1 PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein; KEGG: shm:Shewmr7_2832 starch synthase YP_964224.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_964225.1 KEGG: she:Shewmr4_2756 glycogen/starch/alpha-glucan phosphorylases; TIGRFAM: glycogen/starch/alpha-glucan phosphorylases; PFAM: glycosyl transferase, family 35 YP_964226.1 KEGG: son:SO1495 glycogen operon protein; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_964227.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_964228.1 KEGG: shm:Shewmr7_2837 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase, family 77 YP_964229.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: shm:Shewmr7_2838 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_964230.1 PFAM: regulatory protein, MarR; KEGG: she:Shewmr4_2761 transcriptional regulator, MarR family YP_964231.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: son:SO1490 alcohol dehydrogenase II YP_964232.1 KEGG: shm:Shewmr7_2841 hypothetical protein YP_964233.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sfr:Sfri_3431 NADH dehydrogenase YP_964234.1 KEGG: son:SO1487 hypothetical protein YP_964235.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_2843 thioesterase superfamily protein YP_964236.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: son:SO1484 isocitrate lyase YP_964237.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_964238.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO1482 TonB-dependent receptor, putative YP_964239.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: shm:Shewmr7_2847 potassium efflux system protein YP_964240.1 KEGG: plu:plu4649 transposase, IS4 family YP_964241.1 KEGG: she:Shewmr4_2770 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: Tetratricopeptide domain protein YP_964242.1 KEGG: shm:Shewmr7_2849 hypothetical protein YP_964243.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: she:Shewmr4_2772 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase YP_964244.1 PFAM: SmpA/OmlA domain protein; KEGG: shm:Shewmr7_2851 SmpA/OmlA domain protein YP_964245.1 PFAM: protein of unknown function UPF0125; KEGG: shm:Shewmr7_2852 protein of unknown function UPF0125 YP_964246.1 PFAM: cyclase/dehydrase; KEGG: shm:Shewmr7_2853 cyclase/dehydrase YP_964247.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_964248.1 KEGG: noc:Noc_0165 hypothetical protein YP_964249.1 KEGG: shm:Shewmr7_0743 hypothetical protein YP_964250.1 KEGG: shm:Shewmr7_0742 hypothetical protein YP_964251.1 KEGG: shm:Shewmr7_0741 hypothetical protein YP_964252.1 KEGG: shm:Shewmr7_0740 hypothetical protein YP_964253.1 KEGG: shm:Shewmr7_0739 hypothetical protein YP_964254.1 KEGG: shm:Shewmr7_0738 putative bacteriophage protein YP_964255.1 KEGG: shm:Shewmr7_0737 hypothetical protein YP_964256.1 TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: shm:Shewmr7_0736 phage tail tape measure protein, TP901 family YP_964257.1 KEGG: shm:Shewmr7_0735 hypothetical protein YP_964258.1 KEGG: shm:Shewmr7_0734 hypothetical protein YP_964259.1 KEGG: shm:Shewmr7_0733 hypothetical protein YP_964260.1 PFAM: protein of unknown function DUF847; KEGG: spt:SPA1608 hypothetical protein YP_964261.1 PFAM: zinc finger, DksA/TraR C4-type; KEGG: shm:Shewmr7_0730 transcriptional regulators, TraR/DksA family YP_964262.1 KEGG: shm:Shewmr7_0729 prophage PSPPH06, putative tail tube protein YP_964263.1 KEGG: shm:Shewmr7_0728 hypothetical protein YP_964264.1 KEGG: hch:HCH_06771 hypothetical protein YP_964265.1 KEGG: shm:Shewmr7_0726 hypothetical protein YP_964266.1 KEGG: shm:Shewmr7_0725 hypothetical protein YP_964267.1 KEGG: shm:Shewmr7_0724 putative phage gene YP_964268.1 KEGG: shm:Shewmr7_0723 hypothetical protein YP_964269.1 TIGRFAM: phage major capsid protein, P2 family; PFAM: phage major capsid protein, P2; KEGG: shm:Shewmr7_0722 phage major capsid protein, P2 family YP_964270.1 PFAM: phage capsid scaffolding; KEGG: shm:Shewmr7_0721 phage capsid scaffolding YP_964271.1 PFAM: protein of unknown function DUF264; putative terminase ATPase subunit; KEGG: shm:Shewmr7_0720 protein of unknown function DUF264 YP_964272.1 TIGRFAM: phage portal protein, PBSX family; PFAM: phage portal protein; KEGG: shm:Shewmr7_0719 phage portal protein, PBSX family YP_964274.1 KEGG: eba:ebA2310 conserved hypothetical protein, predicted prevent-host-death family protein YP_964275.1 PFAM: phage transcriptional activator, Ogr/delta; KEGG: shm:Shewmr7_0718 phage transcriptional activator, Ogr/delta YP_964276.1 PFAM: bacteriophage replication gene A; KEGG: spt:SPA2623 putative phage gene YP_964277.1 KEGG: mag:amb2057 site-specific DNA methylase YP_964279.1 KEGG: shm:Shewmr7_0705 hypothetical protein YP_964280.1 PFAM: phage regulatory CII family protein; KEGG: shm:Shewmr7_0702 phage regulatory CII family protein YP_964281.1 KEGG: yps:YPTB1770 putative regulator for prophage CP-933T (Escherichia coli O157:H7) YP_964282.1 PFAM: bacteriophage CI repressor; KEGG: shm:Shewmr7_0700 bacteriophage CI repressor YP_964283.1 KEGG: pat:Patl_0676 hypothetical protein YP_964284.1 KEGG: mmp:MMP0423 hypothetical protein YP_964287.1 PFAM: phage integrase family protein; KEGG: stm:STM2739 phage tail-like protein YP_964288.1 PFAM: KAP P-loop domain protein; KEGG: she:Shewmr4_3681 kap P-loop domain protein YP_964290.1 PFAM: UspA domain protein; KEGG: sfr:Sfri_0791 UspA domain protein YP_964291.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sfr:Sfri_0790 sulphate transporter YP_964292.1 KEGG: hch:HCH_00506 hypothetical protein YP_964293.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfr:Sfri_4001 major facilitator superfamily MFS_1 YP_964294.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate YP_964295.1 KEGG: cps:CPS_3356 redox-active disulfide protein 2 YP_964296.1 PFAM: permease; KEGG: sfr:Sfri_1725 permease YP_964297.1 PFAM: regulatory protein, ArsR; KEGG: son:SO0532 arsenical resistence operon repressor YP_964298.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: sfr:Sfri_4004 transcriptional regulator, ArsR family protein YP_964299.1 PFAM: regulatory protein, ArsR; KEGG: son:SO0502 transcriptional regulator, ArsR family YP_964300.1 PFAM: permease; KEGG: son:SO0503 hypothetical protein YP_964301.1 PFAM: peptidase S24, S26A and S26B; SMART: helix-turn-helix domain protein; KEGG: aeh:Mlg_1999 putative phage repressor YP_964302.1 KEGG: sgl:SG0361 hypothetical protein YP_964303.1 KEGG: cvi:CV2153 hypothetical protein YP_964304.1 PFAM: Integrase, catalytic region; MuA-transposase/repressor protein CI, DNA-binding; KEGG: pol:Bpro_3752 integrase, catalytic region YP_964305.1 KEGG: pol:Bpro_3753 prophage MuSo1, DNA transposition protein, putative YP_964306.1 KEGG: son:SO0645 hypothetical protein YP_964307.1 KEGG: mag:amb0449 hypothetical protein YP_964308.1 KEGG: son:SO0647 hypothetical protein YP_964310.1 KEGG: pat:Patl_1844 hypothetical protein YP_964311.1 KEGG: ecs:ECs4974 putative major head subunit YP_964312.1 KEGG: son:SO0652 prophage MuSo1, positive regulator of late transcription, putative YP_964314.1 TIGRFAM: phage tape measure protein; KEGG: vvy:VV2164 phage-related minor tail protein YP_964315.1 PFAM: glutathione synthase, ATP-binding; KEGG: vfi:VF0976 glutathione synthetase YP_964316.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: dsy:DSY4609 putative oxidoreductase iron-sulfur subunit YP_964317.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: dsy:DSY4131 putative anaerobic dehydrogenase YP_964318.1 PFAM: Arsenical resistance operon trans-acting repressor ArsD; KEGG: dar:Daro_2638 arsenical resistance operon trans-acting repressor ArsD YP_964319.1 KEGG: dar:Daro_2637 anion-transporting ATPase; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase; SMART: AAA ATPase YP_964320.1 TIGRFAM: arsenical pump membrane protein; PFAM: Arsenical pump membrane protein; Citrate transporter; KEGG: sbo:SBO_3500 arsenical pump membrane protein YP_964321.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase; KEGG: sbo:SBO_3501 arsenate reductase YP_964322.1 PFAM: cytochrome c biogenesis protein, transmembrane region; KEGG: bth:BT0800 hypothetical protein YP_964323.1 KEGG: mhu:Mhun_0869 hypothetical protein YP_964324.1 TIGRFAM: redox-active disulfide protein 2; KEGG: plt:Plut_1705 redox-active disulfide protein 2 YP_964325.1 PFAM: regulatory protein, ArsR; KEGG: dps:DP0944 similar to ArsR-family transcription regulator YP_964326.1 PFAM: protein of unknown function DUF1063; KEGG: shm:Shewmr7_2876 protein of unknown function DUF1063 YP_964327.1 PFAM: YheO domain protein; KEGG: son:SO1402 hypothetical protein YP_964328.1 KEGG: shm:Shewmr7_2878 hypothetical protein YP_964329.1 PFAM: protein of unknown function DUF368; KEGG: shm:Shewmr7_2879 protein of unknown function DUF368 YP_964330.1 KEGG: shm:Shewmr7_2880 hypothetical protein YP_964331.1 PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: son:SO1397 cytosine deaminase YP_964332.1 PFAM: protein of unknown function DUF405; protein of unknown function DUF418; KEGG: son:SO1396 hypothetical protein YP_964333.1 PFAM: protein of unknown function DUF1294; KEGG: son:SO1395 membrane protein,putative YP_964334.1 PFAM: short chain fatty acid transporter; KEGG: shm:Shewmr7_2886 short chain fatty acid transporter YP_964335.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO1390 peptidyl-prolyl cis-trans isomerase, FKBP-type YP_964336.1 PFAM: ROK family protein; KEGG: son:SO1389 ROK family protein YP_964337.1 PFAM: peptidase M24; KEGG: shm:Shewmr7_2890 peptidase M24 YP_964338.1 KEGG: son:SO1387 HD domain protein YP_964339.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; KEGG: shm:Shewmr7_2891 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor YP_964340.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO1383 ATP-dependent RNA helicase, DEAD box family YP_964341.1 KEGG: shm:Shewmr7_2893 hypothetical protein YP_964342.1 KEGG: shm:Shewmr7_2895 hypothetical protein YP_964343.1 KEGG: son:SO1379 hypothetical protein YP_964344.1 TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein; KEGG: son:SO1378 ThiJ/PfpI family protein YP_964346.1 PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase-like; KEGG: ecj:JW5272 predicted oxidoreductase YP_964347.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: sbo:SBO_1458 putative oxidoreductase, Fe-S subunit YP_964348.1 KEGG: shm:Shewmr7_2577 decaheme cytochrome c YP_964349.1 PFAM: band 7 protein; KEGG: son:SO1377 hypothetical protein YP_964350.1 PFAM: protein of unknown function DUF1449; KEGG: shm:Shewmr7_2900 protein of unknown function DUF1449 YP_964351.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1374 acetyltransferase, GNAT family YP_964352.1 PFAM: protein of unknown function DUF486; KEGG: she:Shewmr4_2821 protein of unknown function DUF486 YP_964353.1 KEGG: shm:Shewmr7_2905 hypothetical protein YP_964354.1 PFAM: RDD domain containing protein; KEGG: she:Shewmr4_2823 RDD domain containing protein YP_964355.1 PFAM: permease YjgP/YjgQ family protein; KEGG: shm:Shewmr7_2907 permease YjgP/YjgQ family protein YP_964356.1 PFAM: permease YjgP/YjgQ family protein; KEGG: she:Shewmr4_2826 permease YjgP/YjgQ family protein YP_964357.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_964358.1 TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: she:Shewmr4_2828 chorismate mutase YP_964359.1 KEGG: she:Shewmr4_2830 hypothetical protein YP_964360.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: shm:Shewmr7_2913 oxidoreductase FAD-binding domain protein YP_964361.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_964362.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_964363.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_964364.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_964365.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_964366.1 Essential for efficient processing of 16S rRNA YP_964367.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_964368.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_964369.1 PFAM: cytochrome c assembly protein; KEGG: shm:Shewmr7_2922 cytochrome c assembly protein YP_964370.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: she:Shewmr4_2841 protein of unknown function DUF21 YP_964371.1 PFAM: protein of unknown function DUF962; KEGG: shm:Shewmr7_2925 protein of unknown function DUF962 YP_964372.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_964373.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_964374.1 TIGRFAM: DNA repair protein RecO; PFAM: Recombination protein O, RecO; KEGG: son:SO1350 DNA repair protein RecO YP_964375.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_964376.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_964377.1 KEGG: shm:Shewmr7_2931 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B YP_964378.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_964379.1 PFAM: Positive regulator of sigma(E), RseC/MucC; KEGG: she:Shewmr4_2851 positive regulator of sigma E, RseC/MucC YP_964380.1 PFAM: MucB/RseB family protein; KEGG: son:SO1344 sigma-E factor regulatory protein RseB YP_964381.1 PFAM: Anti sigma-E protein RseA family protein; Anti sigma-E protein RseA domain protein; KEGG: she:Shewmr4_2853 anti sigma-E protein, RseA YP_964382.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_964383.1 catalyzes the formation of oxaloacetate from L-aspartate YP_964384.1 KEGG: son:SO1340 hypothetical protein YP_964385.1 PFAM: protein of unknown function DUF339; KEGG: shm:Shewmr7_2939 protein of unknown function DUF339 YP_964386.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_964387.1 KEGG: son:SO1337 hypothetical protein YP_964388.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_964389.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_964390.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_964391.1 PFAM: protein of unknown function DUF81; KEGG: son:SO1333 hypothetical protein YP_964392.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; GAF domain protein; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein; KEGG: she:Shewmr4_2864 PTSINtr with GAF domain, PtsP YP_964393.1 hydrolyzes diadenosine polyphosphate YP_964394.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_964395.1 KEGG: shm:Shewmr7_2949 putative adenylate/guanylate cyclase YP_964396.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2950 transcriptional regulator, LysR family YP_964397.1 PFAM: Hpt domain protein; KEGG: shm:Shewmr7_2951 Hpt protein YP_964398.1 KEGG: shm:Shewmr7_2952 conserved hypothetical radical SAM protein; TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_964399.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_964400.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_964401.1 PFAM: purine and other phosphorylases, family 1; KEGG: she:Shewmr4_2874 methylthioadenosine nucleosidase YP_964402.1 PFAM: cobalamin biosynthesis protein CbiB; KEGG: son:SO1321 CobD-related protein YP_964403.1 KEGG: shm:Shewmr7_2958 hypothetical protein YP_964404.1 PFAM: protein of unknown function UPF0126; KEGG: shm:Shewmr7_2959 protein of unknown function UPF0126 YP_964405.1 KEGG: she:Shewmr4_2878 hypothetical protein YP_964406.1 KEGG: son:SO1317 hypothetical protein YP_964407.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_964408.1 PFAM: peptidase M23B; Opacity-associated protein A, N-terminal domain protein; KEGG: she:Shewmr4_2881 peptidase M23B YP_964409.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_964410.1 KEGG: shm:Shewmr7_2969 hypothetical protein YP_964411.1 KEGG: she:Shewmr4_2888 hypothetical protein YP_964412.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_964413.1 KEGG: she:Shewmr4_2890 hypothetical protein YP_964414.1 PFAM: Cl- channel, voltage-gated family protein; KEGG: shm:Shewmr7_2973 Cl-channel, voltage-gated family protein YP_964415.1 Catalyzes the conversion of carbamoyl phosphate and l-aspartate to yield orthophosphate and n-carbamoyl-l-aspartate YP_964416.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_964417.1 PFAM: Citrate transporter; KEGG: she:Shewmr4_2894 citrate transporter YP_964418.1 KEGG: she:Shewmr4_2895 general secretion pathway protein B YP_964419.1 PFAM: Peptidoglycan-binding domain 1 protein; SMART: AAA ATPase; KEGG: she:Shewmr4_2896 peptidoglycan-binding domain 1 protein YP_964420.1 PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: shm:Shewmr7_2979 metal dependent phosphohydrolase YP_964421.1 KEGG: shm:Shewmr7_2980 major outer membrane lipoprotein, putative YP_964422.1 KEGG: son:SO1294 ribosomal RNA large subunit methyltransferase A, putative YP_964423.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_964424.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: she:Shewmr4_2901 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_964425.1 TIGRFAM: dihydroneopterin aldolase; KEGG: shm:Shewmr7_2984 dihydroneopterin aldolase YP_964426.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_964427.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_964428.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_964429.1 PFAM: GatB/Yqey domain protein; KEGG: she:Shewmr4_2906 GatB/YqeY domain protein YP_964430.1 KEGG: shm:Shewmr7_2989 DNA primase; TIGRFAM: DNA primase; PFAM: zinc finger, CHC2-family protein; TOPRIM domain protein; DNA primase DnaG, DnaB-binding; DNA primase catalytic core, N-terminal domain; SMART: Toprim sub domain protein YP_964431.1 TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma factor RpoD domain protein; PFAM: sigma-70 1.1 domain protein; sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70, non-essential domain protein; sigma-70 region 1.2; KEGG: she:Shewmr4_2908 RNA polymerase, sigma 70 subunit, RpoD YP_964432.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_2991 methyl-accepting chemotaxis sensory transducer YP_964433.1 TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor, type I/II extracellular region; major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_2992 amino acid/peptide transporter YP_964434.1 PFAM: luciferase family protein; KEGG: she:Shewmr4_2911 luciferase family protein YP_964435.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_964436.1 KEGG: son:SO1275 succinate-semialdehyde dehydrogenase (NADP+); TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_964437.1 PFAM: FAD dependent oxidoreductase; KEGG: shm:Shewmr7_2996 FAD dependent oxidoreductase YP_964438.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2997 binding-protein-dependent transport systems inner membrane component YP_964439.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2998 binding-protein-dependent transport systems inner membrane component YP_964440.1 KEGG: shm:Shewmr7_2999 spermidine/putrescine ABC transporter ATPase subunit; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_964441.1 PFAM: extracellular solute-binding protein, family 1; KEGG: she:Shewmr4_2918 extracellular solute-binding protein, family 1 YP_964442.1 PFAM: glutamine synthetase, catalytic region; KEGG: she:Shewmr4_2919 glutamate--ammonia ligase YP_964443.1 PFAM: peptidase C26; KEGG: she:Shewmr4_2920 peptidase C26 YP_964444.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; KEGG: son:SO1265 transcriptional regulator, putative YP_964445.1 PFAM: FAD dependent oxidoreductase; KEGG: son:SO1264 hypothetical oxidoreductase YP_964446.1 KEGG: son:SO1262 hypothetical protein YP_964447.1 PFAM: Rhodanese domain protein; KEGG: son:SO1261 mercaptopyruvate sulfurtransferase YP_964448.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; KEGG: shm:Shewmr7_3007 rare lipoprotein A YP_964449.1 KEGG: xcv:XCV0132 putative secreted protein YP_964450.1 PFAM: aldehyde dehydrogenase; KEGG: she:Shewmr4_2926 aldehyde dehydrogenase (NAD(+)) YP_964451.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_964452.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: she:Shewmr4_2928 methylmalonate-semialdehyde dehydrogenase YP_964453.1 PFAM: protein of unknown function DUF861, cupin_3; KEGG: shm:Shewmr7_3011 protein of unknown function DUF861, cupin_3 YP_964454.1 KEGG: shm:Shewmr7_3012 hypothetical protein YP_964455.1 TIGRFAM: glucose/galactose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: son:SO3503 glucose/galactose transporter YP_964456.1 KEGG: she:Shewmr4_2933 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase YP_964457.1 PFAM: sugar isomerase (SIS); KEGG: shm:Shewmr7_3016 glutamine--fructose-6-phosphate transaminase (isomerizing) YP_964458.1 PFAM: ATPase, BadF/BadG/BcrA/BcrD type; KEGG: shm:Shewmr7_3017 ATPase, BadF/BadG/BcrA/BcrD type YP_964459.1 PFAM: glycoside hydrolase, family 20; Carbohydrate-binding, chitobiase/hexosaminidase-type domain protein; glycoside hydrolase, family 20 domain protein; KEGG: she:Shewmr4_2936 beta-N-acetylhexosaminidase YP_964460.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_3024 TonB-dependent receptor YP_964461.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: shm:Shewmr7_3025 transcriptional regulator, LacI family YP_964462.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: shm:Shewmr7_3026 NADH dehydrogenase YP_964463.1 PFAM: nitrogen regulatory protein P-II; KEGG: shm:Shewmr7_3027 nitrogen regulatory protein P-II YP_964464.1 KEGG: shm:Shewmr7_3028 methylation site containing protein YP_964465.1 KEGG: shm:Shewmr7_3029 methylation site containing protein YP_964466.1 KEGG: she:Shewmr4_2948 hypothetical protein YP_964467.1 KEGG: shm:Shewmr7_3031 methylation site containing protein YP_964468.1 KEGG: she:Shewmr4_2950 type IV pilin biogenesis protein, putative YP_964469.1 KEGG: she:Shewmr4_2951 type IV pilus assembly protein PilX YP_964470.1 KEGG: shm:Shewmr7_3034 prepilin-type cleavage/methylation-like protein YP_964471.1 TIGRFAM: type IV pilus modification protein PilV; KEGG: shm:Shewmr7_3035 type IV pilus modification protein PilV YP_964472.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_964473.1 KEGG: shm:Shewmr7_3037 peptidylprolyl isomerase, FKBP-type YP_964474.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_964475.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_964476.1 KEGG: she:Shewmr4_2958 riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase YP_964477.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: she:Shewmr4_2959 integral membrane protein MviN YP_964478.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_964479.1 PFAM: regulatory protein, ArsR; KEGG: shm:Shewmr7_3043 transcriptional regulator, ArsR family YP_964480.1 PFAM: peptidase M20; peptidase M28; KEGG: she:Shewmr4_2962 peptidase M28 YP_964481.1 PFAM: protein of unknown function DUF328; KEGG: shm:Shewmr7_3045 protein of unknown function DUF328 YP_964482.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: she:Shewmr4_2964 amino acid carrier protein YP_964483.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: son:SO3542 putative phosphoketolase YP_964484.1 PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: son:SO3545 OmpA family protein YP_964485.1 KEGG: shm:Shewmr7_3049 transaldolase; TIGRFAM: transaldolase; PFAM: Transaldolase YP_964486.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_964487.1 KEGG: shm:Shewmr7_3051 hypothetical protein YP_964488.1 PFAM: Hemerythrin HHE cation binding domain protein; KEGG: shm:Shewmr7_3052 hemerythrin HHE cation binding domain protein YP_964489.1 KEGG: she:Shewmr4_2971 hypothetical protein YP_964490.1 PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2; KEGG: shm:Shewmr7_3054 RNA polymerase, sigma-24 subunit, ECF subfamily YP_964491.1 PFAM: von Willebrand factor, type A; KEGG: son:SO3552 von Willebrand factor type A domain protein YP_964492.1 putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_964493.1 KEGG: she:Shewmr4_2975 phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_964494.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_964495.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: shm:Shewmr7_3059 diguanylate cyclase with GAF sensor YP_964496.1 KEGG: she:Shewmr4_2978 hypothetical protein YP_964497.1 KEGG: shm:Shewmr7_3061 hypothetical protein YP_964498.1 involved in the first step of glutathione biosynthesis YP_964499.1 PFAM: peptidase M16 domain protein; KEGG: she:Shewmr4_2981 peptidase M16 domain protein YP_964500.1 KEGG: she:Shewmr4_2982 hypothetical protein YP_964501.1 PFAM: sodium:dicarboxylate symporter; KEGG: shm:Shewmr7_3065 sodium:dicarboxylate symporter YP_964502.1 KEGG: shm:Shewmr7_3066 hypothetical protein YP_964503.1 KEGG: she:Shewmr4_2985 sodium ion-translocating decarboxylase, beta subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit YP_964504.1 catalyzes the formation of pyruvate from oxaloacetate YP_964505.1 TIGRFAM: sodium pump decarboxylases, gamma subunit; PFAM: sodium pump decarboxylase, gamma subunit; KEGG: she:Shewmr4_2987 sodium pump decarboxylases, gamma subunit YP_964506.1 KEGG: son:SO2875 ISSod10, transposase OrfB YP_964507.1 KEGG: son:SO0211 ISSod10, transposase OrfA YP_964508.1 KEGG: son:SO3575 CDP-diacylglycerol--serine O-phosphatidyltransferase, putative; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_964509.1 KEGG: shm:Shewmr7_3071 hypothetical protein YP_964510.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3072 ATPase AAA-2 domain protein YP_964511.1 PFAM: protein of unknown function DUF152; KEGG: son:SO3578 conserved hypothetical protein TIGR00726 YP_964512.1 KEGG: shm:Shewmr7_3074 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_964513.1 KEGG: shm:Shewmr7_3075 putative lipoprotein YP_964514.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_3076 methyl-accepting chemotaxis sensory transducer YP_964515.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: she:Shewmr4_2997 pseudouridine synthase, Rsu YP_964516.1 PFAM: Helix-turn-helix, type 11 domain protein; KEGG: she:Shewmr4_2998 putative transcriptional regulator YP_964517.1 PFAM: NADPH-dependent FMN reductase; KEGG: shm:Shewmr7_3080 NADPH-dependent FMN reductase YP_964518.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: shm:Shewmr7_3081 glyoxalase/bleomycin resistance protein/dioxygenase YP_964519.1 KEGG: son:SO3587 hypothetical protein YP_964520.1 PFAM: GPR1/FUN34/yaaH family protein; KEGG: son:SO3588 gpr1/fun34/YaaH family protein YP_964521.1 KEGG: shm:Shewmr7_3084 hypothetical protein YP_964522.1 PFAM: MltA-interacting MipA family protein; KEGG: son:SO3592 putative outer membrane protein YP_964523.1 KEGG: shm:Shewmr7_3086 hypothetical protein YP_964524.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3087 two component transcriptional regulator, winged helix family YP_964525.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_3007 periplasmic sensor signal transduction histidine kinase YP_964526.1 PFAM: protein of unknown function DUF1289; KEGG: shm:Shewmr7_3089 protein of unknown function DUF1289 YP_964527.1 KEGG: she:Shewmr4_3009 hypothetical protein YP_964528.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_964529.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein, family 1; KEGG: she:Shewmr4_3012 sulfate ABC transporter, periplasmic sulfate-binding protein YP_964530.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO3600 sulfate ABC transporter, permease protein YP_964531.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysW; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO3601 sulfate ABC transporter, permease protein YP_964532.1 KEGG: son:SO3602 sulfate ABC transporter, ATP-binding protein; TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_964533.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_964534.1 PFAM: pseudouridine synthase; KEGG: sdn:Sden_0688 pseudouridine synthase YP_964535.1 KEGG: she:Shewmr4_3021 hypothetical protein YP_964536.1 PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_3103 tetratricopeptide TPR_2 repeat protein YP_964539.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: she:Shewmr4_0913 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_964540.1 KEGG: shm:Shewmr7_3108 hypothetical protein YP_964541.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_964542.1 PFAM: Nucleotidyl transferase; KEGG: son:SO3634 nucleotidyltransferase family protein YP_964543.1 PFAM: aminoglycoside phosphotransferase; KEGG: she:Shewmr4_0909 aminoglycoside phosphotransferase YP_964544.1 PFAM: OstA family protein; Organic solvent tolerance protein; KEGG: shm:Shewmr7_3112 organic solvent tolerance protein YP_964545.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: she:Shewmr4_0907 PpiC-type peptidyl-prolyl cis-trans isomerase YP_964546.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_964547.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_964548.1 protein associated with Co2+ and Mg2+ efflux YP_964549.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_964550.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_0902 methyl-accepting chemotaxis sensory transducer YP_964551.1 KEGG: son:SO3645 hypothetical protein YP_964552.1 PFAM: dihydrofolate reductase region; KEGG: shm:Shewmr7_3120 dihydrofolate reductase YP_964553.1 KEGG: son:SO3647 hypothetical protein YP_964554.1 PFAM: protein of unknown function DUF1212; KEGG: she:Shewmr4_0898 protein of unknown function DUF1212 YP_964555.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_964556.1 involved in the peptidyltransferase reaction during translation YP_964557.1 PFAM: ribosomal protein L21; KEGG: sdn:Sden_2927 ribosomal protein L21 YP_964558.1 PFAM: Polyprenyl synthetase; KEGG: shm:Shewmr7_3126 trans-hexaprenyltranstransferase YP_964559.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_964560.1 KEGG: son:SO3655 pilin, putative YP_964561.1 KEGG: son:SO3656 hypothetical protein YP_964562.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shm:Shewmr7_3132 lysine exporter protein (LysE/YggA) YP_964563.1 KEGG: she:Shewmr4_0888 thiol:disulfide interchange protein, putative YP_964564.1 KEGG: she:Shewmr4_0887 transcriptional regulator, fis family; TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; AAA ATPase YP_964565.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_3136 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_964566.1 PFAM: AMP-dependent synthetase and ligase; KEGG: shm:Shewmr7_3139 AMP-dependent synthetase and ligase YP_964567.1 KEGG: she:Shewmr4_0882 lipid A ABC exporter family, fused ATPase and inner membrane subunits; TIGRFAM: lipid A ABC exporter family, fused ATPase and inner membrane subunits; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_964568.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding; KEGG: son:SO3667 hypothetical protein YP_964569.1 PFAM: protein of unknown function DUF1008; KEGG: son:SO3668 hypothetical protein YP_964570.1 TIGRFAM: TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO3669 heme transport protein YP_964571.1 TIGRFAM: TonB family protein; KEGG: son:SO3670 TonB1 protein YP_964572.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: son:SO3671 TonB system transport protein ExbB1 YP_964573.1 KEGG: son:SO3672 TonB system transport protein ExbD1 YP_964574.1 TIGRFAM: Hg(II)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; KEGG: sfr:Sfri_3492 transcriptional regulator, MerR family protein YP_964575.1 PFAM: Mercuric transport protein MerT; KEGG: sfr:Sfri_3491 mercuric transport protein MerT YP_964576.1 TIGRFAM: mercuric transport protein periplasmic component; PFAM: Heavy metal transport/detoxification protein; KEGG: sfr:Sfri_3490 mercuric transport protein periplasmic component YP_964577.1 TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; Heavy metal transport/detoxification protein; KEGG: sfr:Sfri_3488 mercuric reductase YP_964578.1 PFAM: Resolvase, N-terminal domain; Resolvase helix-turn-helix domain protein; KEGG: xac:XACb0071 Tn5045 resolvase YP_964579.1 KEGG: stm:PSLT044 putative integrase protein YP_964580.1 SMART: AAA ATPase; KEGG: psp:PSPPH_B0059 ExeA-like protein YP_964582.1 KEGG: son:SO3672 TonB system transport protein ExbD1 YP_964583.1 PFAM: periplasmic binding protein; KEGG: son:SO3673 hemin ABC transporter, periplasmic hemin-binding protein YP_964584.1 PFAM: transport system permease protein; KEGG: son:SO3674 hemin ABC transporter, permease protein YP_964585.1 with HmuTU is involved in the transport of hemin YP_964586.1 KEGG: son:SO3676 hypothetical protein YP_964588.1 PFAM: protein of unknown function DUF1568; KEGG: son:SO1890 hypothetical protein YP_964589.1 KEGG: sfr:Sfri_0964 hypothetical protein YP_964590.1 PFAM: peptidase M17, leucyl aminopeptidase domain protein; KEGG: shm:Shewmr7_0987 peptidase M17, leucyl aminopeptidase domain protein YP_964591.1 KEGG: she:Shewmr4_0948 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_964592.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: ilo:IL2191 predicted permease, DMT superfamily YP_964593.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: ilo:IL2190 transcriptional regulator, LysR family YP_964594.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_964595.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_0946 methyl-accepting chemotaxis sensory transducer YP_964596.1 TIGRFAM: bacterioferritin; PFAM: Ferritin, Dps family protein; KEGG: son:SO1112 bacterioferritin subunit 1 YP_964597.1 TIGRFAM: bacterioferritin; PFAM: Ferritin, Dps family protein; KEGG: shm:Shewmr7_0982 bacterioferritin YP_964598.1 PFAM: protein of unknown function DUF539; KEGG: shm:Shewmr7_0981 protein of unknown function DUF539 YP_964599.1 PFAM: ApbE family lipoprotein; KEGG: she:Shewmr4_0942 ApbE family lipoprotein YP_964600.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_964601.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_964602.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_964603.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_964604.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_964605.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_964606.1 PFAM: TonB-dependent receptor; KEGG: she:Shewmr4_0935 TonB-dependent receptor YP_964607.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_964608.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: shm:Shewmr7_0971 TRAP dicarboxylate transporter-DctP subunit YP_964609.1 PFAM: BolA family protein; KEGG: shm:Shewmr7_0970 BolA family protein YP_964610.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: shm:Shewmr7_0969 2OG-Fe(II) oxygenase YP_964611.1 PFAM: methyltransferase small; Methyltransferase type 11; Methyltransferase type 12; KEGG: she:Shewmr4_0930 rRNA (guanine-N(2)-)-methyltransferase YP_964612.1 KEGG: son:SO1096 hypothetical protein YP_964613.1 KEGG: shm:Shewmr7_0966 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_964614.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: shm:Shewmr7_0965 transcriptional regulator, GntR family YP_964615.1 PFAM: cytochrome bd ubiquinol oxidase, subunit I; KEGG: shm:Shewmr7_0964 cytochrome bd ubiquinol oxidase, subunit I YP_964616.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II; KEGG: shm:Shewmr7_0963 cytochrome d ubiquinol oxidase, subunit II YP_964617.1 KEGG: son:SO1094 hypothetical transcription elongation factor YP_964618.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: shm:Shewmr7_0961 transcriptional regulator, AraC family YP_964619.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: son:SO1091 hypothetical protein YP_964620.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_0924 methyl-accepting chemotaxis sensory transducer YP_964621.1 PFAM: Na+/H+ antiporter NhaC; KEGG: shm:Shewmr7_0954 Na+/H+ antiporter NhaC YP_964622.1 KEGG: she:Shewmr4_0918 hypothetical protein YP_964623.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: shm:Shewmr7_0952 pseudouridine synthase, Rsu YP_964624.1 KEGG: sal:Sala_1423 hypothetical protein YP_964625.1 KEGG: shm:Shewmr7_0949 hypothetical protein YP_964626.1 PFAM: aromatic amino acid permease; Amino acid transporter, transmembrane; KEGG: shm:Shewmr7_0948 aromatic amino acid permease YP_964627.1 PFAM: protein of unknown function UPF0016; KEGG: she:Shewmr4_3028 protein of unknown function UPF0016 YP_964628.1 KEGG: son:SO1004 hypothetical protein YP_964629.1 KEGG: son:SO1003 hypothetical protein YP_964630.1 PFAM: sodium/calcium exchanger membrane region; KEGG: son:SO1001 calcium/proton antiporter YP_964631.1 PFAM: Rhomboid family protein; KEGG: son:SO1000 rhomboid family protein YP_964632.1 KEGG: son:SO0973 hypothetical protein YP_964633.1 PFAM: Methyltransferase type 12; KEGG: son:SO0972 hypothetical protein YP_964634.1 KEGG: she:Shewmr4_0809 hypothetical protein YP_964635.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO0970 fumarate reductase flavoprotein subunit precursor YP_964636.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: shm:Shewmr7_3216 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein YP_964637.1 PFAM: dienelactone hydrolase; KEGG: she:Shewmr4_0806 dienelactone hydrolase YP_964640.1 KEGG: psb:Psyr_4989 hypothetical protein YP_964641.1 KEGG: shm:Shewmr7_3219 hypothetical protein YP_964642.1 PFAM: Spermine synthase; KEGG: shm:Shewmr7_3220 spermine synthase YP_964643.1 PFAM: peptidase M17, leucyl aminopeptidase domain protein; KEGG: shm:Shewmr7_3221 leucyl aminopeptidase YP_964644.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: son:SO0958 alkyl hydroperoxide reductase, C subunit YP_964645.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glutaredoxin; KEGG: son:SO0956 alkyl hydroperoxide reductase, F subunit YP_964646.1 KEGG: son:SO0955 hypothetical protein YP_964647.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO0954 acetyltransferase, GNAT family YP_964648.1 KEGG: son:SO0953 hypothetical protein YP_964649.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: shm:Shewmr7_3226 single-stranded-DNA-specific exonuclease RecJ YP_964650.1 KEGG: shm:Shewmr7_3227 thiol:disulfide interchange protein DsbC YP_964651.1 TIGRFAM: tyrosine recombinase XerD; PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: shm:Shewmr7_3228 tyrosine recombinase XerD YP_964652.1 PFAM: branched-chain amino acid transport system II carrier protein; KEGG: she:Shewmr4_0794 branched-chain amino acid transport system II carrier protein YP_964653.1 PFAM: O-methyltransferase, family 3; Methyltransferase type 11; Methyltransferase type 12; KEGG: she:Shewmr4_0793 methyltransferase small YP_964654.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_964655.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_3234 efflux transporter, RND family, MFP subunit YP_964656.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_3235 acriflavin resistance protein YP_964657.1 PFAM: Radical SAM domain protein; KEGG: son:SO0944 hypothetical protein YP_964658.1 KEGG: she:Shewmr4_0786 putative PAS/PAC sensor protein YP_964659.1 KEGG: shm:Shewmr7_3238 hypothetical protein YP_964660.1 KEGG: she:Shewmr4_0784 hypothetical protein YP_964661.1 PFAM: transcriptional regulator domain protein; KEGG: son:SO0940 transcriptional regulator-related protein YP_964662.1 KEGG: shm:Shewmr7_3241 cytochrome c, putative YP_964663.1 KEGG: she:Shewmr4_0781 hypothetical protein YP_964664.1 KEGG: she:Shewmr4_0778 Na+/H+ antiporter YP_964665.1 PFAM: protein of unknown function DUF481; KEGG: shm:Shewmr7_3246 protein of unknown function DUF481 YP_964666.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_964667.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_964668.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_964669.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_964670.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_964671.1 KEGG: shm:Shewmr7_3252 hypothetical protein YP_964672.1 PFAM: transposase IS66; KEGG: pha:PSHAa0410 transposase YP_964673.1 PFAM: IS66 Orf2 family protein; KEGG: pha:PSHAa0409 hypothetical protein YP_964675.1 PFAM: protein of unknown function DUF1568; KEGG: shm:Shewmr7_1178 protein of unknown function DUF1568 YP_964676.1 KEGG: shm:Shewmr7_3253 hypothetical protein YP_964677.1 KEGG: shm:Shewmr7_3255 acetyltransferase, GNAT family YP_964678.1 KEGG: she:Shewmr4_0766 hypothetical protein YP_964679.1 PFAM: protein of unknown function DUF306, Meta and HslJ; KEGG: shm:Shewmr7_3258 protein of unknown function DUF306, MetA and HslJ YP_964680.1 PFAM: sodium:dicarboxylate symporter; KEGG: shm:Shewmr7_3259 sodium:dicarboxylate symporter YP_964681.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_3261 GCN5-related N-acetyltransferase YP_964682.1 PFAM: aromatic amino acid permease; KEGG: son:SO0919 serine transporter, putative YP_964683.1 PFAM: peptidase S45, penicillin amidase; KEGG: shm:Shewmr7_3263 peptidase S45, penicillin amidase YP_964684.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_964685.1 PFAM: GCN5-related N-acetyltransferase; regulatory protein, MarR; KEGG: shm:Shewmr7_3265 transcriptional regulator, MarR family with acetyltransferase activity YP_964686.1 SMART: AAA ATPase; KEGG: rfr:Rfer_3382 hypothetical protein YP_964687.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_964688.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_964689.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_964690.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_964691.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_964692.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_964693.1 PFAM: aldo/keto reductase; KEGG: shm:Shewmr7_3273 aldo/keto reductase YP_964694.1 PFAM: MltA-interacting MipA family protein; KEGG: sfr:Sfri_3058 MltA-interacting MipA family protein YP_964695.1 KEGG: sfr:Sfri_3059 hypothetical protein YP_964696.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: sdn:Sden_0558 ATP-binding region, ATPase-like protein YP_964697.1 PFAM: transcriptional regulator domain protein; KEGG: sdn:Sden_0557 response regulator receiver YP_964698.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sdn:Sden_0557 response regulator receiver YP_964699.1 KEGG: sfr:Sfri_3063 hypothetical protein YP_964700.1 PFAM: MltA-interacting MipA family protein; KEGG: sfr:Sfri_3064 MltA-interacting MipA family protein YP_964701.1 TIGRFAM: cysteine desulfurases, SufS subfamily; PFAM: aminotransferase, class V; aminotransferase, class I and II; KEGG: son:SO3789 aminotransferase, class V YP_964702.1 PFAM: Fe-S metabolism associated SufE; KEGG: shm:Shewmr7_0835 Fe-S metabolism associated SufE YP_964703.1 PFAM: peptidase M19, renal dipeptidase; KEGG: shm:Shewmr7_0834 twin-arginine translocation pathway signal YP_964704.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: shm:Shewmr7_0832 cupin 2, conserved barrel domain protein YP_964705.1 KEGG: shm:Shewmr7_0831 hypothetical protein YP_964706.1 PFAM: peptidase U32; KEGG: shm:Shewmr7_0828 peptidase U32 YP_964707.1 PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_0827 pseudouridylate synthase YP_964708.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_964709.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; KEGG: son:SO1915 serine protease, subtilase family YP_964710.1 PFAM: ABC-2 type transporter; KEGG: she:Shewmr4_3143 ABC-2 type transporter YP_964711.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO3802 ABC transporter, ATP-binding protein YP_964712.1 KEGG: shm:Shewmr7_0822 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_964713.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; KEGG: shm:Shewmr7_0821 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_964714.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: shm:Shewmr7_0820 UDP-N-acetylmuramate YP_964715.1 KEGG: she:Shewmr4_3148 hypothetical protein YP_964716.1 KEGG: she:Shewmr4_3149 sterol desaturase family protein YP_964717.1 KEGG: she:Shewmr4_3150 hypothetical protein YP_964718.1 KEGG: shm:Shewmr7_0816 OmpA domain protein transmembrane region-containing protein YP_964719.1 PFAM: uncharacterized lipoprotein; KEGG: shm:Shewmr7_0815 uncharacterized lipoprotein YP_964720.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: shm:Shewmr7_0814 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_964721.1 KEGG: shm:Shewmr7_0813 hypothetical protein YP_964722.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO3814 AmpG protein, putative YP_964723.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_964724.1 PFAM: VanZ family protein; KEGG: she:Shewmr4_3157 VanZ family protein YP_964725.1 KEGG: she:Shewmr4_3158 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein YP_964726.1 PFAM: nitrogen regulatory protein P-II; KEGG: shm:Shewmr7_0808 nitrogen regulatory protein P-II YP_964727.1 PFAM: EAL domain protein; KEGG: son:SO3821 rtn protein YP_964728.1 PFAM: protein of unknown function DUF819; KEGG: sfr:Sfri_2589 protein of unknown function DUF819 YP_964729.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sfr:Sfri_2588 transcriptional regulator, LysR family protein YP_964730.1 KEGG: she:Shewmr4_3227 outer membrane porin, putative YP_964731.1 PFAM: transposase Tn5, dimerisation domain protein; KEGG: ppr:PBPRB0910 hypothetical transposase YP_964732.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_964733.1 PFAM: protein of unknown function DUF819; KEGG: shm:Shewmr7_0802 protein of unknown function DUF819 YP_964734.1 KEGG: shm:Shewmr7_0801 hypothetical protein YP_964735.1 PFAM: Invasion gene expression up-regulator, SirB; KEGG: shm:Shewmr7_0800 invasion gene expression up-regulator, SirB YP_964736.1 KEGG: shm:Shewmr7_0799 GCN5-related N-acetyltransferase YP_964738.1 KEGG: cgb:cg1190 hypothetical protein YP_964739.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: she:Shewmr4_3168 modification methylase, HemK family YP_964740.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_964741.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_964742.1 PFAM: outer membrane lipoprotein LolB; KEGG: son:SO3835 outer membrane lipoprotein LolB YP_964743.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_964744.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_964745.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_0792 methyl-accepting chemotaxis sensory transducer YP_964746.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: son:SO3840 RNA polymerase sigma-70 factor, ECF subfamily YP_964747.1 KEGG: she:Shewmr4_3176 hypothetical protein YP_964748.1 KEGG: she:Shewmr4_3177 hypothetical protein YP_964749.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: shm:Shewmr7_0788 pseudouridine synthase, Rsu YP_964750.1 PFAM: peptidase M13, neprilysin; peptidase M13; KEGG: she:Shewmr4_3179 endothelin-converting enzyme 1 YP_964751.1 KEGG: she:Shewmr4_3180 hypothetical protein YP_964752.1 KEGG: she:Shewmr4_3181 hypothetical protein YP_964753.1 KEGG: shm:Shewmr7_0784 hypothetical protein YP_964754.1 PFAM: membrane-flanked domain; KEGG: son:SO3849 hypothetical protein YP_964755.1 KEGG: she:Shewmr4_3186 putative manganese transporter YP_964756.1 PFAM: protein of unknown function DUF1456; KEGG: shm:Shewmr7_0779 protein of unknown function DUF1456 YP_964757.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_964758.1 KEGG: son:SO3856 hypothetical protein YP_964759.1 TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: shm:Shewmr7_0771 putative iron-sulfur cluster binding protein YP_964760.1 PFAM: porin, Gram-negative type; KEGG: son:SO3896 outer membrane porin, putative YP_964761.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: she:Shewmr4_3226 UBA/ThiF-type NAD/FAD binding protein YP_964762.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO3894 sensor histidine kinase YP_964763.1 KEGG: she:Shewmr4_3224 hypothetical protein YP_964764.1 KEGG: sfr:Sfri_0507 hypothetical protein YP_964765.1 TIGRFAM: hemerythrin-like metal-binding protein; PFAM: chemotaxis sensory transducer; Hemerythrin HHE cation binding domain protein; KEGG: son:SO3890 methyl-accepting chemotaxis protein YP_964766.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_964767.1 KEGG: shm:Shewmr7_0759 L-sorbosone dehydrogenase, putative YP_964768.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_964769.1 PFAM: protein of unknown function UPF0227; KEGG: she:Shewmr4_3232 protein of unknown function UPF0227 YP_964770.1 PFAM: metallophosphoesterase; Calcineurin phosphoesterase C-terminal domain protein; KEGG: she:Shewmr4_3233 calcineurin phosphoesterase C-terminal domain protein YP_964771.1 PFAM: protein of unknown function DUF1249; KEGG: son:SO3902 hypothetical protein YP_964772.1 PFAM: NUDIX hydrolase; KEGG: son:SO3903 ADP-ribose pyrophosphatase YP_964773.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_964774.1 KEGG: she:Shewmr4_3237 hypothetical protein YP_964775.1 KEGG: shm:Shewmr7_0751 hypothetical protein YP_964776.1 PFAM: protein of unknown function DUF461; KEGG: son:SO3907 hypothetical protein YP_964777.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: shm:Shewmr7_0749 enoyl-CoA hydratase/isomerase YP_964778.1 KEGG: she:Shewmr4_3241 phage shock protein C, PspC YP_964779.1 KEGG: shm:Shewmr7_0747 hypothetical protein YP_964780.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase, DuS; KEGG: she:Shewmr4_3243 TIM-barrel protein, YjbN family YP_964781.1 KEGG: shm:Shewmr7_0696 putative chemotaxis protein CheX YP_964782.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_964783.1 KEGG: son:SO3917 replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase, N-terminal domain protein; DnaB domain protein helicase, C-terminal domain protein; SMART: AAA ATPase YP_964784.1 KEGG: shm:Shewmr7_0691 hypothetical protein YP_964785.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_964786.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_964787.1 binds single-stranded DNA at the primosome assembly site YP_964788.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_964789.1 PFAM: protein of unknown function DUF481; KEGG: she:Shewmr4_3261 protein of unknown function DUF481 YP_964790.1 PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_3262 major facilitator superfamily MFS_1 YP_964791.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_964792.1 KEGG: shm:Shewmr7_0683 ribonuclease R; TIGRFAM: VacB and RNase II family 3'-5' exoribonucleases; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; Ribonuclease B, OB region N-terminal domain; Ribonuclease R winged-helix domain protein; SMART: Cold shock protein YP_964793.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: shm:Shewmr7_0682 Sel1 domain protein repeat-containing protein YP_964794.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_964795.1 KEGG: shm:Shewmr7_0680 hypothetical protein YP_964796.1 forms a direct contact with the tRNA during translation YP_964797.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_964798.1 PFAM: AFG1-family ATPase; KEGG: she:Shewmr4_3270 AFG1-family ATPase YP_964799.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: she:Shewmr4_3271 protease Do YP_964800.1 TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: son:SO3943 protease DegS YP_964801.1 PFAM: Radical SAM domain protein; KEGG: vpa:VPA0443 hypothetical protein YP_964802.1 PFAM: Radical SAM domain protein; KEGG: vpa:VPA0442 hypothetical protein YP_964804.1 PFAM: protein of unknown function DUF1234; KEGG: son:SO4650 hypothetical protein YP_964805.1 KEGG: son:SO4651 hypothetical protein YP_964806.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein, family 1; KEGG: son:SO4652 sulfate ABC transporter, periplasmic sulfate-binding protein YP_964807.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO4653 sulfate ABC transporter, permease protein YP_964808.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysW; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO4654 sulfate ABC transporter, permease protein YP_964809.1 KEGG: son:SO4655 sulfate ABC transporter, ATP-binding protein; TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_964810.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: dge:Dgeo_0011 methionine gamma-lyase YP_964811.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: ilo:IL0163 2OG-Fe(II) oxygenase superfamily protein YP_964812.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_964813.1 PFAM: BolA family protein; KEGG: shm:Shewmr7_3338 BolA family protein YP_964814.1 KEGG: son:SO3950 SpoIIAA family protein YP_964815.1 PFAM: toluene tolerance family protein; KEGG: shm:Shewmr7_3340 toluene tolerance family protein YP_964816.1 PFAM: Mammalian cell entry related domain protein; KEGG: son:SO3952 mce-related protein YP_964817.1 PFAM: protein of unknown function DUF140; KEGG: son:SO3953 putative membrane protein YP_964818.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_3343 ABC transporter related YP_964819.1 KEGG: shm:Shewmr7_3344 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_964820.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_964821.1 PFAM: protein of unknown function DUF1239; KEGG: son:SO3958 hypothetical protein YP_964822.1 PFAM: OstA family protein; KEGG: son:SO3959 hypothetical protein YP_964823.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_3348 ABC transporter related YP_964824.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_964825.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: shm:Shewmr7_3350 sigma 54 modulation protein/ribosomal protein S30EA YP_964826.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: shm:Shewmr7_3351 PTS IIA-like nitrogen-regulatory protein PtsN YP_964827.1 PFAM: uncharacterized P-loop ATPase protein UPF0042; KEGG: shm:Shewmr7_3352 uncharacterized P-loop ATPase protein UPF0042 YP_964828.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: she:Shewmr4_0669 phosphocarrier, HPr family YP_964829.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: son:SO3966 magnesium transporter YP_964830.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; KEGG: she:Shewmr4_0667 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_964831.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen; KEGG: she:Shewmr4_0666 OmpA/MotB domain protein YP_964832.1 PFAM: transposase IS3/IS911 family protein; KEGG: shm:Shewmr7_3357 transposase IS3/IS911 family protein YP_964833.1 PFAM: protein of unknown function RIO1; KEGG: shm:Shewmr7_3358 protein of unknown function RIO1 YP_964834.1 KEGG: shm:Shewmr7_3360 hypothetical protein YP_964835.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_964836.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_964837.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO0702 MATE efflux family protein YP_964838.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0701 transcriptional regulator, LysR family YP_964839.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_0551 efflux transporter, RND family, MFP subunit YP_964840.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_0550 acriflavin resistance protein YP_964841.1 KEGG: son:SO0764 hypothetical protein YP_964842.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: she:Shewmr4_3366 lysine exporter protein (LysE/YggA) YP_964843.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: shm:Shewmr7_0586 transcriptional regulator, AraC family YP_964844.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO0737 TonB-dependent receptor, putative YP_964845.1 KEGG: son:SO0735 hypothetical protein YP_964846.1 PFAM: transcriptional regulator PadR family protein; KEGG: son:SO0734 hypothetical protein YP_964847.1 PFAM: Thioredoxin domain; KEGG: she:Shewmr4_3375 thioredoxin domain YP_964848.1 KEGG: son:SO0728 hypothetical protein YP_964849.1 PFAM: protein of unknown function DUF134; Sigma-70, region 4 type 2; KEGG: son:SO0727 hypothetical protein YP_964850.1 KEGG: she:Shewmr4_3376 hypothetical protein YP_964851.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: she:Shewmr4_3377 ABC transporter related YP_964852.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_964853.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase, dimerisation and phosphoacceptor region; KEGG: shm:Shewmr7_3364 signal transduction histidine kinase, nitrate/nitrite-specific, NarQ YP_964854.1 PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: shm:Shewmr7_3365 two component transcriptional regulator, LuxR family YP_964855.1 PFAM: uncharacterized conserved protein UCP006287; KEGG: she:Shewmr4_0656 uncharacterized conserved protein UCP006287 YP_964856.1 PFAM: Mg2+ transporter protein, CorA family protein; KEGG: shm:Shewmr7_3367 Mg2 transporter protein, CorA family protein YP_964857.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_964858.1 KEGG: son:SO3987 hypothetical protein YP_964859.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3371 two component transcriptional regulator, winged helix family YP_964860.1 PFAM: peptidase S15; peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9B, dipeptidylpeptidase IV domain protein; KEGG: shm:Shewmr7_3372 peptidase S9B, dipeptidylpeptidase IV domain protein YP_964861.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_964863.1 PFAM: IS66 Orf2 family protein; KEGG: pha:PSHAa0409 hypothetical protein YP_964864.1 PFAM: transposase IS66; KEGG: pha:PSHAa0410 transposase YP_964865.1 PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: nmu:Nmul_A0119 cytidine/deoxycytidylate deaminase, zinc-binding region YP_964866.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria; KEGG: nmu:Nmul_A1193 transport-associated YP_964867.1 PFAM: uncharacterized protein UPF0114; KEGG: son:SO3997 hypothetical protein YP_964868.1 PFAM: chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: pha:PSHAa2387 chemotaxis sensory protein YP_964869.1 PFAM: sodium:dicarboxylate symporter; KEGG: she:Shewmr4_0642 sodium:dicarboxylate symporter YP_964870.1 KEGG: son:SO4005 hypothetical protein YP_964871.1 KEGG: shm:Shewmr7_3380 hypothetical protein YP_964872.1 KEGG: shm:Shewmr7_3381 hypothetical protein YP_964873.1 KEGG: she:Shewmr4_0638 hypothetical protein YP_964874.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: she:Shewmr4_0637 two component transcriptional regulator, LuxR family YP_964875.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_0636 periplasmic sensor signal transduction histidine kinase YP_964876.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: she:Shewmr4_0635 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_964877.1 PFAM: Polysulphide reductase, NrfD; KEGG: she:Shewmr4_0634 polysulphide reductase, NrfD YP_964878.1 PFAM: molydopterin dinucleotide-binding region; KEGG: she:Shewmr4_0633 molydopterin dinucleotide-binding region YP_964879.1 KEGG: she:Shewmr4_0632 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_964880.1 KEGG: son:SO4011 hypothetical protein YP_964881.1 KEGG: son:SO4012 hypothetical protein YP_964882.1 KEGG: shm:Shewmr7_3401 hypothetical protein YP_964883.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: son:SO0635 peptidyl-prolyl cis-trans isomerase C YP_964884.1 KEGG: she:Shewmr4_0624 penicillin-binding protein 1B; TIGRFAM: penicillin-binding protein 1B; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_964885.1 KEGG: shm:Shewmr7_3407 ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; Helicase ATP-dependent, C-terminal domain protein; SMART: DEAD-like helicases-like YP_964886.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: she:Shewmr4_0621 diguanylate cyclase/phosphodiesterase YP_964887.1 KEGG: son:SO0625 hypothetical protein YP_964888.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_964889.1 KEGG: shm:Shewmr7_3413 hypothetical protein YP_964890.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3414 two component transcriptional regulator, winged helix family YP_964891.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: shm:Shewmr7_3415 periplasmic sensor signal transduction histidine kinase YP_964892.1 KEGG: she:Shewmr4_0614 hypothetical protein YP_964893.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_964894.1 PFAM: arginine N-succinyltransferase beta subunit; KEGG: shm:Shewmr7_3418 arginine N-succinyltransferase YP_964895.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_964896.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: shm:Shewmr7_3420 alpha/beta hydrolase fold-3 domain protein YP_964897.1 PFAM: HDOD; KEGG: she:Shewmr4_0609 putative signal transduction protein YP_964898.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9B, dipeptidylpeptidase IV domain protein; KEGG: shm:Shewmr7_3422 peptidase S9, prolyl oligopeptidase active site domain protein YP_964899.1 TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: she:Shewmr4_0607 glutamine amidotransferase of anthranilate synthase YP_964900.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: son:SO4028 single-strand binding protein YP_964901.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO4029 transporter, putative YP_964902.1 TIGRFAM: excinuclease ABC, A subunit; PFAM: ABC transporter related; KEGG: son:SO4030 excinuclease ABC, A subunit YP_964903.1 PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO4034 ATP-dependent RNA helicase DeaD YP_964904.1 KEGG: she:Shewmr4_3425 hypothetical protein YP_964905.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO4039 hydrolase, haloacid dehalogenase-like family YP_964906.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: son:SO4040 integral membrane domain protein YP_964907.1 KEGG: son:SO4042 hydratase/decarboxylase family protein YP_964908.1 TIGRFAM: TonB family protein; KEGG: son:SO4043 TonB domain protein YP_964909.1 KEGG: son:SO4044 hypothetical protein YP_964910.1 KEGG: psp:PSPPH_1876 hypothetical protein YP_964912.1 PFAM: cytochrome c, class I; KEGG: son:SO4047 cytochrome c family protein YP_964913.1 KEGG: shm:Shewmr7_0519 cytochrome c family protein YP_964914.1 KEGG: she:Shewmr4_3433 hypothetical protein YP_964915.1 PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_0517 secretion protein HlyD family protein YP_964916.1 PFAM: regulatory protein, MarR; KEGG: she:Shewmr4_3435 transcriptional regulator, MarR family YP_964917.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: son:SO4053 methyl-accepting chemotaxis protein YP_964918.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_964919.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_964920.1 KEGG: son:SO4056 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_964921.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_964922.1 PFAM: protein of unknown function DUF81; KEGG: son:SO4058 hypothetical protein YP_964923.1 PFAM: Polysulphide reductase, NrfD; KEGG: son:SO4060 polysulfide reductase, subunit C YP_964924.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4061 polysulfide reductase, subunit B YP_964925.1 KEGG: she:Shewmr4_3445 pentapeptide repeat protein YP_964926.1 KEGG: shm:Shewmr7_0505 hypothetical protein YP_964927.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_964928.1 PFAM: transposase Tn5, dimerisation domain protein; KEGG: plu:plu4494 transposase, IS4 family YP_964929.1 KEGG: she:Shewmr4_2242 diguanylate phosphodiesterase YP_964930.1 PFAM: MORN variant repeat protein; KEGG: fnu:FN2119 hypothetical exported 24-amino acid repeat protein YP_964931.1 PFAM: OmpA domain protein transmembrane region-containing protein; KEGG: sfr:Sfri_0734 OmpA domain protein transmembrane region-containing protein YP_964932.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_3717 TonB-dependent siderophore receptor YP_964933.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_0501 methyltransferase type 11 YP_964934.1 PFAM: EAL domain protein; KEGG: tcx:Tcr_0028 diguanylate phosphodiesterase (EAL domain) YP_964935.1 PFAM: protein of unknown function DUF541; KEGG: shm:Shewmr7_0500 protein of unknown function DUF541 YP_964936.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_964937.1 TIGRFAM: fumarate hydratase, class II; PFAM: fumarate lyase; KEGG: chu:CHU_3664 fumarate hydratase/aspartate ammonia-lyase YP_964938.1 PFAM: protein of unknown function DUF331; KEGG: shm:Shewmr7_0498 protein of unknown function DUF331 YP_964939.1 KEGG: shm:Shewmr7_0497 hypothetical protein YP_964940.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO4077 TonB-dependent receptor, putative YP_964941.1 PFAM: peptidase U62, modulator of DNA gyrase; KEGG: she:Shewmr4_3455 peptidase U62, modulator of DNA gyrase YP_964942.1 PFAM: protein of unknown function DUF615; KEGG: shm:Shewmr7_0494 protein of unknown function DUF615 YP_964943.1 PFAM: Ig domain protein, group 1 domain protein; KEGG: shm:Shewmr7_0493 Ig domain protein, group 1 domain protein YP_964944.1 PFAM: MgtC/SapB transporter; KEGG: pcr:Pcryo_2508 MgtC/SapB transporter YP_964945.1 PFAM: Catalase domain protein; KEGG: nmu:Nmul_A1515 catalase YP_964946.1 KEGG: bam:Bamb_5633 hypothetical protein YP_964947.1 KEGG: pfo:Pfl_3517 hypothetical protein YP_964948.1 PFAM: amino acid permease-associated region; KEGG: she:Shewmr4_3458 amino acid permease-associated region YP_964949.1 PFAM: Ion transport protein; KEGG: sde:Sde_1761 cold shock protein YP_964950.1 PFAM: ABC-2 type transporter; KEGG: she:Shewmr4_3461 ABC-2 type transporter YP_964951.1 PFAM: ABC-2 type transporter; KEGG: son:SO4088 conserved hypothetical protein YP_964952.1 PFAM: secretion protein HlyD family protein; KEGG: son:SO4089 HlyD family secretion protein YP_964953.1 PFAM: outer membrane efflux protein; KEGG: shm:Shewmr7_0487 outer membrane efflux protein YP_964954.1 PFAM: peptidase U62, modulator of DNA gyrase; KEGG: son:SO4091 TldD protein YP_964955.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: son:SO4092 hydrolase, carbon-nitrogen family YP_964956.1 KEGG: she:Shewmr4_3467 hypothetical protein YP_964957.1 involved in the processing of the 5'end of 16S rRNA YP_964958.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: shm:Shewmr7_0482 maf protein YP_964959.1 PFAM: Rod shape-determining protein MreD; KEGG: son:SO4096 rod shape-determining protein MreD YP_964960.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_964961.1 functions in MreBCD complex in some organisms YP_964962.1 KEGG: shm:Shewmr7_0478 MSHA biogenesis protein MshQ YP_964963.1 KEGG: shm:Shewmr7_0477 MSHA biogenesis protein MshP YP_964964.1 KEGG: son:SO4102 MSHA biogenesis protein MshO YP_964965.1 KEGG: shm:Shewmr7_0475 methylation site containing protein YP_964966.1 KEGG: son:SO4104 MSHA pilin protein MshC YP_964967.1 KEGG: she:Shewmr4_3478 methylation site containing protein YP_964968.1 KEGG: she:Shewmr4_3479 methylation site containing protein YP_964969.1 KEGG: son:SO4106 MSHA pilin protein MshB YP_964970.1 KEGG: son:SO4107 hypothetical protein YP_964971.1 PFAM: type II secretion system protein; KEGG: son:SO4108 MSHA biogenesis protein MshG YP_964972.1 PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; KEGG: shm:Shewmr7_0469 type II secretion system protein E YP_964973.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: son:SO4110 MSHA biogenesis protein MshN, putative YP_964974.1 KEGG: she:Shewmr4_3485 MSHA biogenesis protein MshM YP_964975.1 TIGRFAM: pilus (MSHA type) biogenesis protein MshL; PFAM: type II and III secretion system protein; Secretin domain protein; Secretin/TonB, short N-terminal domain; KEGG: she:Shewmr4_3486 pilus (MSHA type) biogenesis protein MshL YP_964976.1 KEGG: shm:Shewmr7_0465 MSHA biogenesis protein MshK YP_964977.1 KEGG: shm:Shewmr7_0464 MSHA biogenesis protein MshJ YP_964978.1 KEGG: shm:Shewmr7_0463 hypothetical protein YP_964979.1 KEGG: son:SO4114.2 hypothetical biogenesis protein MshI YP_964980.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_964981.1 PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: shm:Shewmr7_0460 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) YP_964982.2 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_964983.1 KEGG: son:SO4121 hypothetical protein YP_964984.1 KEGG: she:Shewmr4_3495 primosomal protein N'; TIGRFAM: primosomal protein N'; PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_964985.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_964986.1 PFAM: Sporulation domain protein; KEGG: son:SO4124 cell division protein FtsN, putative YP_964987.1 KEGG: son:SO4126 hypothetical protein YP_964988.1 PFAM: band 7 protein; KEGG: son:SO4128 SPFH domain/Band 7 family protein YP_964989.1 PFAM: band 7 protein; KEGG: son:SO4129 SPFH domain/Band 7 family protein YP_964990.1 PFAM: protein of unknown function DUF107; KEGG: shm:Shewmr7_0449 protein of unknown function DUF107 YP_964991.1 KEGG: shm:Shewmr7_0448 hypothetical protein YP_964992.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_964993.1 PFAM: protein of unknown function DUF465; KEGG: son:SO4134 hypothetical protein YP_964994.1 PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: son:SO4136 decarboxylase, pyridoxal-dependent YP_964995.1 KEGG: shm:Shewmr7_0444 hypothetical protein YP_964996.1 PFAM: MscS Mechanosensitive ion channel; KEGG: she:Shewmr4_3509 MscS mechanosensitive ion channel YP_964997.1 KEGG: son:SO4139 hypothetical protein YP_964998.1 KEGG: pat:Patl_1924 hypothetical protein YP_964999.1 PFAM: Xanthine/uracil/vitamin C permease; KEGG: son:SO4150 transporter, putative YP_965000.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_3516 histidine kinase YP_965001.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: shm:Shewmr7_0436 two component transcriptional regulator, LuxR family YP_965002.1 KEGG: she:Shewmr4_3518 hypothetical protein YP_965003.1 PFAM: bifunctional deaminase-reductase domain protein; KEGG: lpn:lpg1988 dihydrofolate reductase YP_965004.1 KEGG: son:SO4159 hypothetical protein YP_965005.1 heat shock protein involved in degradation of misfolded proteins YP_965006.1 heat shock protein involved in degradation of misfolded proteins YP_965007.1 PFAM: protein of unknown function DUF971; KEGG: she:Shewmr4_3523 protein of unknown function DUF971 YP_965008.1 KEGG: shm:Shewmr7_0431 hypothetical protein YP_965009.1 PFAM: deoxyribodipyrimidine photolyase-related protein; KEGG: shm:Shewmr7_0429 deoxyribodipyrimidine photolyase-related protein YP_965010.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: she:Shewmr4_3527 short-chain dehydrogenase/reductase SDR YP_965011.1 KEGG: she:Shewmr4_3528 hypothetical protein YP_965012.1 PFAM: response regulator receiver; helix-turn-helix, Fis-type; KEGG: she:Shewmr4_3529 response regulator receiver protein YP_965013.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_3530 periplasmic sensor signal transduction histidine kinase YP_965014.1 PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_0418 pseudouridine synthase YP_965015.1 KEGG: son:SO4182 ATP-dependent protease La (LON) domain protein, putative YP_965016.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_3540 TonB-dependent receptor YP_965017.1 PFAM: conserved hypothetical protein 22; KEGG: shm:Shewmr7_0414 conserved hypothetical protein 22 YP_965018.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_965019.1 KEGG: shm:Shewmr7_0412 DedA family protein YP_965020.1 PFAM: chemotaxis sensory transducer; KEGG: ilo:IL1068 methyl-accepting chemotaxis protein with ligand-binding sensor domain and HAMP domain YP_965021.1 KEGG: she:Shewmr4_3545 hypothetical protein YP_965022.1 KEGG: shm:Shewmr7_0410 hypothetical protein YP_965023.1 PFAM: phosphoesterase, PA-phosphatase related; KEGG: son:SO4195 PAP2 family protein YP_965024.1 KEGG: shm:Shewmr7_0408 hypothetical protein YP_965025.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_965026.1 PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: she:Shewmr4_3550 arginase/agmatinase/formiminoglutamase YP_965027.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferases; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO4199 ubiquinone/menaquinone biosynthesis methlytransferase UbiE YP_965028.1 PFAM: protein of unknown function DUF1243; KEGG: son:SO4200 conserved hypothetical protein YP_965029.1 TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: ABC-1 domain protein; KEGG: shm:Shewmr7_0403 2-polyprenylphenol 6-hydroxylase YP_965030.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: shm:Shewmr7_0402 twin-arginine translocation protein, TatA/E family subunit YP_965031.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; KEGG: shm:Shewmr7_0401 twin-arginine translocation protein, TatB subunit YP_965032.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: she:Shewmr4_3556 sec-independent protein translocase, TatC subunit YP_965033.1 KEGG: son:SO4205 hypothetical protein YP_965034.1 PFAM: TatD-related deoxyribonuclease; KEGG: shm:Shewmr7_0398 TatD-related deoxyribonuclease YP_965035.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Diverse 7TM receptor, extracellular region 2; Diverse 7TM receptor, transmembrane region; KEGG: son:SO4207 GGDEF domain protein YP_965036.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_965037.1 KEGG: sfr:Sfri_1559 ISSod10, transposase OrfB YP_965038.1 PFAM: RNP-1 like RNA-binding protein; KEGG: shm:Shewmr7_0175 RNP-1 like RNA-binding protein YP_965039.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_965040.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_965041.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_965042.1 PFAM: fatty acid desaturase; KEGG: son:SO0197 fatty acid desaturase, family 1 YP_965043.1 catalyzes the formation of selenophosphate from selenide and ATP YP_965044.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_965045.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: son:SO0194 acyltransferase family protein YP_965046.1 PFAM: regulatory protein, TetR; KEGG: she:Shewmr4_0172 transcriptional regulator, TetR family YP_965047.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_0166 GCN5-related N-acetyltransferase YP_965048.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: shm:Shewmr7_0165 3'(2'),5'-bisphosphate nucleotidase YP_965049.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_965050.1 PFAM: Fibronectin, type III domain protein; Ig family protein; SMART: Dystroglycan-type cadherin domain protein; KEGG: son:SO0189 fibronectin type III domain protein YP_965051.1 PFAM: phage Tail Collar domain protein; KEGG: sdn:Sden_3729 phage tail collar YP_965052.1 PFAM: GCN5-related N-acetyltransferase; KEGG: hch:HCH_06057 acetyltransferase YP_965053.1 KEGG: son:SO0181 hypothetical protein YP_965054.1 PFAM: Phytanoyl-CoA dioxygenase; KEGG: son:SO0180 hypothetical protein YP_965055.1 PFAM: Aspartyl/Asparaginyl beta-hydroxylase; KEGG: son:SO0179 hypothetical protein YP_965056.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_0162 HAD-superfamily hydrolase, subfamily IA, variant 3 YP_965057.1 PFAM: type II secretion system protein N; KEGG: shm:Shewmr7_0161 type II secretion system protein N YP_965058.1 PFAM: General secretion pathway M protein; KEGG: son:SO0175 general secretion pathway protein M YP_965059.1 TIGRFAM: general secretion pathway protein L; PFAM: General secretion pathway L; KEGG: she:Shewmr4_0164 general secretion pathway protein L YP_965060.1 PFAM: General secretion pathway protein K; KEGG: she:Shewmr4_0163 general secretion pathway protein K YP_965061.1 TIGRFAM: general secretion pathway protein J; KEGG: son:SO0172 general secretion pathway protein J YP_965062.1 TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: shm:Shewmr7_0156 general secretion pathway protein I YP_965063.1 TIGRFAM: general secretion pathway protein H; KEGG: son:SO0170 general secretion pathway protein H YP_965064.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: shm:Shewmr7_0154 general secretion pathway protein G YP_965065.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein; KEGG: son:SO0168 general secretion pathway protein F YP_965066.1 KEGG: shm:Shewmr7_0152 general secretory pathway protein E; TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_965067.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: shm:Shewmr7_0151 general secretion pathway protein D YP_965068.1 TIGRFAM: general secretion pathway protein C; KEGG: she:Shewmr4_0155 general secretion pathway protein C YP_965069.1 PFAM: RNA-binding S4 domain protein; KEGG: shm:Shewmr7_0149 RNA-binding S4 domain protein YP_965070.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_965071.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_965072.1 KEGG: tde:TDE0520 hypothetical protein YP_965074.1 KEGG: son:SOA0067 hypothetical protein YP_965075.1 PFAM: Hemerythrin HHE cation binding domain protein; KEGG: she:Shewmr4_0398 hemerythrin HHE cation binding domain protein YP_965076.1 PFAM: AAA-4 family protein; KEGG: shm:Shewmr7_3628 putative transcriptional regulator YP_965077.1 PFAM: HupE/UreJ protein; KEGG: she:Shewmr4_0396 HupE/UreJ protein YP_965078.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: she:Shewmr4_0395 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_965079.1 TIGRFAM: tyrosine recombinase XerC; PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: son:SO4306 integrase/recombinase XerC YP_965080.1 PFAM: protein of unknown function DUF484; KEGG: shm:Shewmr7_3632 protein of unknown function DUF484 YP_965081.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_965082.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: shm:Shewmr7_3634 diaminopimelate decarboxylase YP_965083.1 KEGG: shm:Shewmr7_3635 hypothetical protein YP_965084.1 PFAM: Frataxin family protein; KEGG: shm:Shewmr7_3636 frataxin family protein YP_965085.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_965086.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_965087.1 PFAM: Uroporphyrinogen III synthase HEM4; KEGG: son:SO4314 uroporphyrinogen-III synthase YP_965088.1 PFAM: protein of unknown function DUF513, hemX; KEGG: shm:Shewmr7_3640 protein of unknown function DUF513, HemX YP_965089.1 PFAM: HemY domain protein; KEGG: she:Shewmr4_0385 HemY domain protein YP_965090.1 TIGRFAM: putative outer membrane adhesin like proteiin; PFAM: Hemolysin-type calcium-binding region; KEGG: shm:Shewmr7_3642 putative outer membrane adhesin like protein YP_965091.1 PFAM: transposase, IS4 family protein; KEGG: sak:SAK_2050 IS10R, transposase YP_965092.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_3644 type I secretion membrane fusion protein, HlyD family YP_965093.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: shm:Shewmr7_3645 type I secretion outer membrane protein, TolC family YP_965094.1 PFAM: OmpA/MotB domain protein; KEGG: she:Shewmr4_0380 OmpA/MotB domain protein YP_965095.1 KEGG: shm:Shewmr7_3647 hypothetical protein YP_965096.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: shm:Shewmr7_3648 diguanylate cyclase/phosphodiesterase YP_965097.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: she:Shewmr4_0377 diguanylate cyclase/phosphodiesterase with GAF sensor YP_965098.1 TIGRFAM: ATP-dependent DNA helicase Rep; PFAM: UvrD/REP helicase; KEGG: she:Shewmr4_0376 ATP-dependent DNA helicase Rep YP_965099.1 PFAM: protein of unknown function DUF526; KEGG: son:SO4329 hypothetical protein YP_965100.1 KEGG: shm:Shewmr7_3653 hypothetical protein YP_965101.1 PFAM: NnrS family protein; KEGG: sfr:Sfri_3037 NnrS family protein YP_965102.1 PFAM: cytochrome c552; KEGG: sfr:Sfri_3036 nitrite reductase (cytochrome; ammonia-forming) YP_965103.1 PFAM: Inner membrane CreD family protein; KEGG: shm:Shewmr7_3656 inner membrane CreD family protein YP_965104.1 PFAM: phosphoesterase, PA-phosphatase related; KEGG: shm:Shewmr7_3657 phosphoesterase, PA-phosphatase related YP_965105.1 PFAM: import inner membrane translocase, subunit Tim44; KEGG: son:SO4340 hypothetical protein YP_965107.1 KEGG: bur:Bcep18194_B1335 hypothetical protein YP_965109.1 PFAM: aminotransferase, class V; KEGG: son:SO4343 aminotransferase, class V YP_965110.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_965111.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_965112.1 PFAM: amino acid-binding ACT domain protein; KEGG: shm:Shewmr7_3663 acetolactate synthase small subunit YP_965113.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_965114.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_965115.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_965116.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: shm:Shewmr7_3667 protein of unknown function DUF21 YP_965117.1 PFAM: protein of unknown function UPF0153; KEGG: she:Shewmr4_0357 protein of unknown function UPF0153 YP_965118.1 PFAM: helix-hairpin-helix motif; KEGG: sdn:Sden_0291 ERCC4 YP_965119.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_965120.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_0340 transcriptional regulator, LysR family YP_965121.1 KEGG: shm:Shewmr7_0339 hypothetical protein YP_965122.1 KEGG: shm:Shewmr7_0338 hypothetical protein YP_965123.1 PFAM: helix-turn-helix domain protein; KEGG: shm:Shewmr7_0337 transcriptional regulator, XRE family YP_965124.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: shm:Shewmr7_0336 filamentation induced by cAMP protein Fic YP_965125.1 KEGG: son:SO0366 hypothetical protein YP_965126.1 PFAM: aminoglycoside phosphotransferase; KEGG: shm:Shewmr7_0333 aminoglycoside phosphotransferase YP_965127.1 KEGG: she:Shewmr4_3611 hypothetical protein YP_965128.1 KEGG: shm:Shewmr7_0331 hypothetical protein YP_965129.1 Essential for recycling GMP and indirectly, cGMP YP_965130.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_965131.1 KEGG: son:SO0359 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; metal-dependent phosphohydrolase, HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase, HD region YP_965132.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: son:SO0358 endoribonuclease L-PSP, putative YP_965133.1 PFAM: AMP-dependent synthetase and ligase; KEGG: son:SO0355 AMP-binding protein YP_965134.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: shm:Shewmr7_0325 Na+/Ca+ antiporter, CaCA family YP_965135.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: hne:HNE_1653 TonB-dependent receptor YP_965136.1 KEGG: shm:Shewmr7_0321 hypothetical protein YP_965137.1 PFAM: superoxide dismutase, copper/zinc binding; KEGG: vch:VC1583 superoxide dismutase, Cu-Zn YP_965138.1 KEGG: son:SO0349 magnesium chelatase family protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_965139.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: son:SO0348 acyltransferase family protein YP_965140.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: she:Shewmr4_3626 phospholipid/glycerol acyltransferase YP_965141.1 PFAM: protein of unknown function DUF523; KEGG: she:Shewmr4_3627 protein of unknown function DUF523 YP_965142.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: shm:Shewmr7_0316 transcriptional regulator, GntR family YP_965143.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_965144.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_965145.2 Catalyzes the conversion of citrate to isocitrate YP_965146.1 TIGRFAM: putative AcnD-accessory protein PrpF; PFAM: protein of unknown function DUF453; KEGG: shm:Shewmr7_0312 putative AcnD-accessory protein PrpF YP_965147.1 KEGG: sil:SPO1470 isocitrate lyase family protein YP_965148.1 KEGG: shm:Shewmr7_0311 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; Two component regulator three Y domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_965149.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_965150.1 PFAM: Modulator of Rho-dependent transcription termination; KEGG: shm:Shewmr7_0308 transcriptional antiterminator, Rof YP_965151.1 KEGG: son:SO0338 hypothetical protein YP_965152.1 PFAM: Endoribonuclease L-PSP; KEGG: son:SO0337 hypothetical translation initiation inhibitor, YjgF family YP_965153.1 PFAM: Na+/H+ antiporter NhaC; KEGG: she:Shewmr4_3639 Na+/H+ antiporter NhaC YP_965154.1 PFAM: protein of unknown function DUF904; KEGG: shm:Shewmr7_0304 protein of unknown function DUF904 YP_965155.1 PFAM: protein of unknown function DUF1107; KEGG: son:SO0334 hypothetical protein YP_965156.1 PFAM: DSBA oxidoreductase; KEGG: son:SO0333 thiol:disulfide interchange protein DsbA YP_965157.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_965158.1 KEGG: she:Shewmr4_3644 hypothetical protein YP_965159.1 PFAM: protein of unknown function UPF0061; KEGG: she:Shewmr4_3645 protein of unknown function UPF0061 YP_965160.1 KEGG: shm:Shewmr7_0298 hypothetical protein YP_965161.1 KEGG: shm:Shewmr7_0297 hypothetical protein YP_965162.1 PFAM: DsrE family protein; KEGG: shm:Shewmr7_0296 DsrE family protein YP_965163.1 KEGG: shm:Shewmr7_0295 hypothetical protein YP_965164.1 KEGG: she:Shewmr4_3650 hypothetical protein YP_965165.1 KEGG: shm:Shewmr7_0293 hypothetical protein YP_965166.1 PFAM: periplasmic binding protein; KEGG: ppu:PP_2591 ferric siderophore ABC transporter, periplasmic siderophore-binding protein YP_965167.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pen:PSEEN2494 ferric siderophore ABC transporter, ATP-binding protein BauE YP_965168.1 PFAM: transport system permease protein; KEGG: pen:PSEEN2495 ferric siderophore ABC transporter, permease protein BauC YP_965169.1 PFAM: transport system permease protein; ABC-3 protein; KEGG: ppu:PP_2594 ferric siderophore ABC transporter, permease protein YP_965170.1 KEGG: rha:RHA1_ro03859 probable tetracycline repressor YP_965171.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: rru:Rru_A2312 TonB-dependent receptor YP_965172.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bur:Bcep18194_B0675 ABC efflux pump, fused inner membrane and ATPase subunits YP_965173.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: nfa:nfa28020 putative ABC transporter YP_965174.1 KEGG: son:SO0321 hypothetical protein YP_965175.1 PFAM: acyltransferase 3; KEGG: she:Shewmr4_3653 acyltransferase 3 YP_965176.1 KEGG: she:Shewmr4_3654 hypothetical protein YP_965177.1 PFAM: protein of unknown function DUF1232; KEGG: she:Shewmr4_3655 protein of unknown function DUF1232 YP_965178.1 KEGG: shm:Shewmr7_0279 hypothetical protein YP_965179.1 KEGG: plu:plu4649 transposase, IS4 family YP_965180.1 PFAM: Orn/Lys/Arg decarboxylase, major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: she:Shewmr4_3667 ornithine decarboxylase YP_965181.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system YP_965182.1 PFAM: porin, Gram-negative type; KEGG: she:Shewmr4_3669 porin, gram-negative type YP_965183.1 PFAM: Radical SAM domain protein; Radical SAM N-terminal domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: son:SO0311 hypothetical Fe-S oxidoreductase YP_965184.1 KEGG: shm:Shewmr7_0274 hypothetical protein YP_965185.1 PFAM: protein of unknown function DUF1212; KEGG: son:SO0308 hypothetical protein YP_965186.1 KEGG: she:Shewmr4_3673 hypothetical protein YP_965187.1 PFAM: ThiJ/PfpI domain protein; KEGG: lbl:LBL_2610 transcriptional regulator, ThiJ/PfpI family protein YP_965188.1 PFAM: regulatory protein, TetR; KEGG: btk:BT9727_2867 transcriptional regulator, TetR family YP_965189.1 KEGG: sdn:Sden_0547 hypothetical protein YP_965190.1 KEGG: sdn:Sden_0546 putative orphan protein YP_965191.1 KEGG: sdn:Sden_0545 hypothetical protein YP_965192.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: shm:Shewmr7_0262 protein of unknown function UPF0011 YP_965193.1 PFAM: LppC family lipoprotein; KEGG: she:Shewmr4_3684 LppC family lipoprotein YP_965194.1 PFAM: protein of unknown function UPF0102; KEGG: shm:Shewmr7_0260 protein of unknown function UPF0102 YP_965195.1 TIGRFAM: phosphoheptose isomerase; KEGG: shm:Shewmr7_0259 phosphoheptose isomerase YP_965196.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria; KEGG: shm:Shewmr7_0258 transport-associated YP_965197.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: shm:Shewmr7_0257 protein of unknown function DUF6, transmembrane YP_965198.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_0256 transcriptional regulator, LysR family YP_965199.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_965200.1 TIGRFAM: phosphoglycolate phosphatase ; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_0254 phosphoglycolate phosphatase YP_965201.1 PFAM: ribulose-phosphate 3-epimerase; Orotidine 5'-phosphate decarboxylase; KEGG: shm:Shewmr7_0253 ribulose-phosphate 3-epimerase YP_965202.1 KEGG: shm:Shewmr7_0252 hypothetical protein YP_965203.1 KEGG: she:Shewmr4_3695 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_965204.1 PFAM: Sporulation domain protein; KEGG: son:SO0288 DamX domain protein YP_965205.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_965206.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_965207.1 TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; Secretin/TonB, short N-terminal domain; KEGG: she:Shewmr4_3699 type IV pilus secretin PilQ YP_965208.1 PFAM: Pilus assembly protein, PilQ; KEGG: shm:Shewmr7_0245 pilus assembly protein, PilQ YP_965209.1 PFAM: Pilus assembly protein, PilO; KEGG: shm:Shewmr7_0244 pilus assembly protein, PilO YP_965210.1 PFAM: transposase, IS4 family protein; KEGG: sak:SAK_2050 IS10R, transposase YP_965211.1 PFAM: Fimbrial assembly family protein; KEGG: shm:Shewmr7_0243 fimbrial assembly family protein YP_965212.1 TIGRFAM: type IV pilus assembly protein PilM; KEGG: son:SO0281 type IV pilus biogenesis protein PilM YP_965213.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; KEGG: shm:Shewmr7_0241 penicillin-binding protein, 1A family YP_965214.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_965215.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_965216.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_965217.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_965218.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_965219.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_965220.1 PFAM: protein of unknown function DUF1439; KEGG: shm:Shewmr7_0234 protein of unknown function DUF1439 YP_965221.1 TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: son:SO0272 competence/damage-inducible protein CinA YP_965222.1 TIGRFAM: DNA binding domain, excisionase family; KEGG: she:Shewmr4_3713 DNA binding domain, excisionase family YP_965223.1 PFAM: formate dehydrogenase, subunit FdhD; KEGG: she:Shewmr4_3714 formate dehydrogenase, subunit FdhD YP_965224.1 KEGG: son:SO4504 hypothetical protein YP_965225.1 KEGG: shm:Shewmr7_3787 hypothetical protein YP_965226.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4506 iron-sulfur cluster-binding protein YP_965227.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: shm:Shewmr7_3789 cytoplasmic chaperone TorD family protein YP_965228.1 KEGG: son:SO4508 hypothetical protein YP_965229.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: son:SO4509 formate dehydrogenase, alpha subunit YP_965230.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4510 formate dehydrogenase, iron-sulfur subunit YP_965231.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: shm:Shewmr7_3793 formate dehydrogenase, gamma subunit YP_965232.1 KEGG: son:SO4512 hypothetical protein YP_965233.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: shm:Shewmr7_3795 twin-arginine translocation pathway signal YP_965234.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_3796 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_965235.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: she:Shewmr4_3726 formate dehydrogenase, gamma subunit YP_965236.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_3798 TonB-dependent receptor YP_965237.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_3819 methyltransferase type 11 YP_965238.1 KEGG: she:Shewmr4_3747 hypothetical protein YP_965239.1 KEGG: son:SO4552 sensory box protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_965240.1 PFAM: DTW domain containing protein; KEGG: son:SO4554 hypothetical protein YP_965241.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: son:SO4555 drug resistance transporter, Bcr/CflA family protein YP_965242.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO4556 transcriptional regulator, LysR family YP_965243.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: son:SO4557 methyl-accepting chemotaxis protein YP_965244.1 KEGG: shm:Shewmr7_3826 hypothetical protein YP_965245.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: she:Shewmr4_3754 Sel1 domain protein repeat-containing protein YP_965246.1 KEGG: shm:Shewmr7_3828 hypothetical protein YP_965247.1 KEGG: she:Shewmr4_3756 hypothetical protein YP_965248.1 PFAM: protein of unknown function DUF1332; KEGG: shm:Shewmr7_3830 protein of unknown function DUF1332 YP_965249.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_965250.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: son:SO4567 transcriptional regulator, AsnC family YP_965251.1 PFAM: Polysulphide reductase, NrfD; KEGG: son:SO4568 formate-dependent nitrite reductase, nrfD protein YP_965252.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: she:Shewmr4_3763 twin-arginine translocation pathway signal YP_965253.1 KEGG: she:Shewmr4_3764 formate-dependent nitrite reductase YP_965254.1 KEGG: she:Shewmr4_3765 hypothetical protein YP_965255.1 PFAM: regulatory protein, LysR; KEGG: shm:Shewmr7_3839 transcriptional regulator, LysR family YP_965256.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_965257.1 PFAM: alpha/beta hydrolase fold; KEGG: shm:Shewmr7_3841 alpha/beta hydrolase fold YP_965258.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_965259.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: son:SO4576 O-succinylbenzoic acid--CoA ligase YP_965260.1 PFAM: EAL domain protein; response regulator receiver; KEGG: pau:PA14_12810 probable two-component response regulator YP_965261.1 PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: pfo:Pfl_4515 two component transcriptional regulator, LuxR family YP_965262.1 KEGG: psb:Psyr_2113 PAS; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold domain protein; SMART: extracellular solute-binding protein, family 3 YP_965263.1 PFAM: pili assembly chaperone; KEGG: rme:Rmet_1663 pili assembly chaperone YP_965264.1 KEGG: yps:YPTB0157 hypothetical protein YP_965265.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: pae:PA2130 probable fimbrial biogenesis usher protein YP_965266.1 PFAM: pili assembly chaperone; KEGG: pau:PA14_37040 chaperone CupA2 YP_965267.1 PFAM: Fimbrial protein; KEGG: bam:Bamb_2833 fimbrial protein YP_965268.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_965269.1 PFAM: protein of unknown function DUF214; KEGG: she:Shewmr4_3772 protein of unknown function DUF214 YP_965270.1 KEGG: shm:Shewmr7_3846 cell division ATP-binding protein FtsE; TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: AAA ATPase YP_965271.1 KEGG: son:SO4586 cell division protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54, G- domain; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase YP_965272.1 TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: she:Shewmr4_3775 putative methyltransferase YP_965273.1 PFAM: protein of unknown function DUF1145; KEGG: son:SO4588 hypothetical protein YP_965274.1 PFAM: NapC/NirT cytochrome c domain protein; KEGG: son:SO4591 tetraheme cytochrome c YP_965275.1 KEGG: son:SOA0156 hypothetical protein YP_965276.1 KEGG: son:SOA0155 hypothetical protein YP_965277.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: son:SOA0154 heavy metal efflux protein, putative YP_965278.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: son:SOA0153 heavy metal efflux pump, CzcA family YP_965279.1 KEGG: gme:Gmet_1465 hypothetical protein YP_965280.1 PFAM: AbgT putative transporter; short chain fatty acid transporter; KEGG: son:SO0160 transporter, putative YP_965282.1 PFAM: sodium:dicarboxylate symporter; KEGG: she:Shewmr4_0147 sodium:dicarboxylate symporter YP_965283.1 KEGG: shm:Shewmr7_0141 hypothetical protein YP_965284.1 PFAM: peptidase M14, carboxypeptidase A; KEGG: she:Shewmr4_0145 peptidase M14, carboxypeptidase A YP_965285.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_0139 methyltransferase type 11 YP_965286.1 KEGG: shm:Shewmr7_0138 lipoprotein, putative YP_965287.1 KEGG: shm:Shewmr7_0137 hypothetical protein YP_965289.1 KEGG: plu:plu4649 transposase, IS4 family YP_965290.1 KEGG: vch:VCA0487 hypothetical protein YP_965291.1 KEGG: vch:VCA0486 hypothetical protein YP_965292.1 PFAM: glycosyl transferase, family 51; KEGG: gbe:GbCGDNIH1_0281 multimodular transpeptidase-transglycosylase PBP 1A YP_965293.1 KEGG: son:SO0148 hypothetical protein YP_965294.1 PFAM: Excinuclease ABC, C subunit domain protein; KEGG: son:SO0145 hypothetical URI domain endonuclease YP_965295.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller; KEGG: she:Shewmr4_0136 oligopeptidase B YP_965296.1 DHBP synthase; functions during riboflavin biosynthesis YP_965297.1 KEGG: shm:Shewmr7_0128 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_965298.1 PFAM: Ferritin, Dps family protein; KEGG: son:SO0139 ferritin YP_965299.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV; KEGG: shm:Shewmr7_0126 molybdenum cofactor synthesis domain YP_965300.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_965301.1 KEGG: she:Shewmr4_0130 hypothetical protein YP_965302.1 PFAM: protein of unknown function DUF890; KEGG: shm:Shewmr7_0122 protein of unknown function DUF890 YP_965303.1 PFAM: flagellar basal body-associated protein FliL; KEGG: she:Shewmr4_0127 flagellar basal body-associated protein FliL YP_965304.1 PFAM: Chorismate lyase; KEGG: son:SO0131 putative chorismate--pyruvate lyase YP_965305.1 PFAM: PKD domain containing protein; peptidase M6, immune inhibitor A; KEGG: shm:Shewmr7_0119 peptidase M6, immune inhibitor A YP_965306.1 PFAM: multiple antibiotic resistance (MarC)-related proteins; KEGG: son:SO0129 conserved hypothetical protein TIGR00427 YP_965307.1 KEGG: shm:Shewmr7_0117 hypothetical protein YP_965308.1 PFAM: protein of unknown function DUF833; KEGG: shm:Shewmr7_0116 protein of unknown function DUF833 YP_965309.1 KEGG: shm:Shewmr7_0115 hypothetical protein YP_965310.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: shm:Shewmr7_0114 phospholipid/glycerol acyltransferase YP_965311.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shm:Shewmr7_0113 lysine exporter protein (LysE/YggA) YP_965312.1 PFAM: MscS Mechanosensitive ion channel; KEGG: shm:Shewmr7_0112 MscS mechanosensitive ion channel YP_965313.1 PFAM: protein of unknown function DUF1090; KEGG: son:SO0119 hypothetical protein YP_965314.1 PFAM: Redoxin domain protein; KEGG: ppr:PBPRB1492 hypothetical thioredoxin YP_965315.1 PFAM: DSBA oxidoreductase; KEGG: vfi:VF2492 copper sensitivity protein ScsC YP_965316.1 KEGG: vpa:VP2006 putative suppressor for copper-sensitivity B precursor YP_965318.1 KEGG: shm:Shewmr7_0110 hypothetical protein YP_965319.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ppr:PBPRA1918 putative glyoxalase family protein YP_965320.1 KEGG: shm:Shewmr7_0108 hypothetical protein YP_965321.1 PFAM: peptidase M48, Ste24p; KEGG: son:SO0110 hypothetical protease YP_965323.1 KEGG: pol:Bpro_1650 hypothetical protein YP_965324.1 PFAM: protein of unknown function DUF548; KEGG: shm:Shewmr7_3921 protein of unknown function DUF548 YP_965325.1 PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: pat:Patl_2246 diguanylate cyclase/phosphodiesterase YP_965326.1 PFAM: protein of unknown function DUF519; KEGG: shm:Shewmr7_3922 protein of unknown function DUF519 YP_965327.1 PFAM: Lytic transglycosylase, catalytic; KEGG: son:SO4660 transglycosylase SLT domain protein YP_965328.1 PFAM: LemA family protein; KEGG: son:SO4662 lemA protein YP_965329.1 PFAM: C4-dicarboxylate anaerobic carrier; AbgT putative transporter; KEGG: she:Shewmr4_3833 AbgT putative transporter YP_965330.1 KEGG: shm:Shewmr7_3927 hypothetical protein YP_965331.1 KEGG: she:Shewmr4_3835 hypothetical protein YP_965332.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_3929 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family YP_965333.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_3837 efflux transporter, RND family, MFP subunit YP_965334.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: she:Shewmr4_3840 glutathione S-transferase, N-terminal domain protein YP_965335.1 KEGG: shm:Shewmr7_3934 hypothetical protein YP_965336.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: son:SO4699 oligopeptidase A YP_965337.1 KEGG: son:SO4700 hypothetical protein YP_965338.1 KEGG: son:SO4701 hypothetical protein YP_965339.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_965340.1 KEGG: ret:RHE_CH02008 hypothetical protein YP_965342.1 PFAM: transposase, IS4 family protein; KEGG: shm:Shewmr7_3098 transposase, IS4 family protein YP_965343.1 PFAM: phage integrase family protein; KEGG: sdn:Sden_3590 transposase, putative YP_965344.1 KEGG: sdn:Sden_3587 hypothetical protein YP_965345.1 KEGG: sdn:Sden_3586 hypothetical protein YP_965346.1 KEGG: sdn:Sden_3584 hypothetical protein YP_965347.1 KEGG: sdn:Sden_3583 hypothetical protein YP_965348.1 KEGG: vpa:VP1086 hypothetical protein YP_965349.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: fra:Francci3_0885 UBA/ThiF-type NAD/FAD binding fold YP_965350.1 KEGG: rme:Rmet_3357 hypothetical protein YP_965351.1 KEGG: shm:Shewmr7_1788 ATP-binding region, ATPase-like protein YP_965352.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: shm:Shewmr7_3940 sodium/proline symporter YP_965353.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_965354.1 TIGRFAM: gamma-glutamyl phosphate reductase; KEGG: shm:Shewmr7_3942 gamma-glutamyl phosphate reductase YP_965355.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_965356.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_965357.1 TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein; KEGG: she:Shewmr4_0098 transcriptional regulator, histidine utilization repressor, GntR family YP_965358.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_965359.1 PFAM: Siderophore-interacting protein; FAD-binding 9, siderophore-interacting domain protein; KEGG: shm:Shewmr7_0091 FAD-binding 9, siderophore-interacting domain protein YP_965360.1 PFAM: regulatory protein, MarR; KEGG: shm:Shewmr7_0090 transcriptional regulator, MarR family YP_965361.1 KEGG: shm:Shewmr7_0143 hypothetical protein YP_965362.1 KEGG: son:SO0090 hypothetical protein YP_965364.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: csa:Csal_2061 glycerophosphoryl diester phosphodiesterase YP_965365.1 KEGG: son:SO0085 hypothetical protein YP_965366.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO0084 HAD-superfamily hydrolase, subfamily IA, variant 1 family protein YP_965367.1 KEGG: sdn:Sden_0075 hypothetical protein YP_965368.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: shm:Shewmr7_0084 glutathione-dependent formaldehyde-activating, GFA YP_965369.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_0081 thioesterase superfamily protein YP_965370.1 KEGG: she:Shewmr4_0083 hypothetical protein YP_965371.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_0078 thioesterase superfamily protein YP_965372.1 KEGG: she:Shewmr4_0079 MORN variant repeat protein YP_965373.1 PFAM: AMP-dependent synthetase and ligase; KEGG: she:Shewmr4_0078 AMP-dependent synthetase and ligase YP_965374.1 KEGG: son:SO0074 hypothetical protein YP_965375.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0073 ABC transporter, ATP-binding protein YP_965376.1 PFAM: regulatory protein GntR, HTH; KEGG: son:SO0072 transcriptional regulator, GntR family YP_965377.1 PFAM: alpha/beta hydrolase fold; TAP domain protein; KEGG: she:Shewmr4_0074 TAP domain protein YP_965378.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0070 ATP-binding transport protein NatA YP_965379.1 KEGG: son:SO0069 transport protein, putative YP_965380.1 KEGG: son:SO0068 hypothetical protein YP_965381.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_965382.1 PFAM: NLP/P60 protein; KEGG: shm:Shewmr7_0059 NLP/P60 protein YP_965383.1 KEGG: eca:ECA0549 putative plasmid transfer protein YP_965384.1 PFAM: Pirin domain protein domain protein; Pirin domain protein; KEGG: shm:Shewmr7_0053 pirin domain protein domain protein YP_965385.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: shm:Shewmr7_0052 periplasmic sensor signal transduction histidine kinase YP_965386.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO0059 transcriptional regulatory protein KdpE YP_965387.1 PFAM: TrkA-N domain protein; KEGG: shm:Shewmr7_0050 TrkA-N domain protein YP_965388.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: shm:Shewmr7_0049 potassium uptake protein, TrkH family YP_965389.1 KEGG: sde:Sde_2764 hypothetical protein YP_965390.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_0049 HI0933 family protein YP_965391.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_965392.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_965393.1 PFAM: Rhodanese domain protein; KEGG: shm:Shewmr7_0044 rhodanese domain protein YP_965394.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_965395.1 PFAM: peptidase M23B; KEGG: shm:Shewmr7_0042 peptidase M23B YP_965396.1 KEGG: she:Shewmr4_0043 carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_965397.1 PFAM: protein of unknown function DUF610, YibQ; KEGG: shm:Shewmr7_0040 protein of unknown function DUF610, YibQ YP_965398.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: she:Shewmr4_0041 transcriptional regulator, BadM/Rrf2 family YP_965399.1 PFAM: protein of unknown function UPF0153; KEGG: son:SO0044 hypothetical protein YP_965400.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4737 iron-sulfur cluster-binding protein YP_965401.1 KEGG: she:Shewmr4_3917 hypothetical protein YP_965402.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_965403.1 KEGG: she:Shewmr4_3919 hypothetical protein YP_965404.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_965405.1 PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein; KEGG: son:SO4742 transcriptional regulator, DeoR family YP_965406.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO4743 TonB-dependent receptor, putative YP_965407.1 KEGG: she:Shewmr4_3923 UDP-N-acetylglucosamine pyrophosphorylase; TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase YP_965408.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_965409.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_965410.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_965411.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_965412.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_965413.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_965414.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_965415.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_965416.1 PFAM: ATP synthase I chain; KEGG: shm:Shewmr7_4024 ATP synthase I chain YP_965417.1 TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: shm:Shewmr7_4025 ParB-like partition proteins YP_965418.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: shm:Shewmr7_4026 cobyrinic acid a,c-diamide synthase YP_965419.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_965420.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_965421.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_965422.1 PFAM: TGF-beta receptor, type I/II extracellular region; KEGG: she:Shewmr4_3938 TGF-beta receptor, type I/II extracellular region YP_965423.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: rso:RSp0312 probable multidrug efflux system transmembrane protein YP_965424.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: rso:RSp0313 probable multidrug efflux system protein YP_965425.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RS05454 probable two component response regulator transcription regulator protein YP_965426.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: rru:Rru_A2930 periplasmic sensor signal transduction histidine kinase YP_965427.1 KEGG: sdn:Sden_3021 integrase, catalytic region YP_965429.1 PFAM: Resolvase, N-terminal domain; Resolvase helix-turn-helix domain protein; KEGG: rha:RHA1_ro03159 resolvase YP_965430.1 PFAM: Eco57I restriction endonuclease; KEGG: ssn:SSO_1583 putative methylase YP_965431.1 PFAM: BsuBIPstI restriction endonuclease domain protein; KEGG: ssn:SSO_1584 putative restriction endonuclease YP_965432.1 KEGG: plu:plu0130 hypothetical protein YP_965434.1 PFAM: phage integrase family protein; KEGG: tcx:Tcr_0833 hypothetical protein YP_965436.1 KEGG: ana:alr8557 hypothetical protein YP_965438.1 PFAM: TraH family protein; KEGG: eci:UTI89_P132 putative ATP-binding F pilus assembly protein YP_965439.1 PFAM: TraG domain protein; KEGG: eba:p1B148 sex pilus assembly YP_965442.1 TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell YP_965444.1 PFAM: plasmid encoded RepA protein; KEGG: xac:XACb0056 replication protein A YP_965445.1 TIGRFAM: DNA binding domain, excisionase family YP_965446.1 PFAM: phage integrase family protein; KEGG: pgi:PG0874 mobilizable transposon, int protein YP_965447.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_965448.1 PFAM: 60 kDa inner membrane insertion protein; KEGG: shm:Shewmr7_4032 60 kDa inner membrane insertion protein YP_965449.1 PFAM: protein of unknown function DUF37; KEGG: son:SO0005 conserved hypothetical protein TIGR00278 YP_965450.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_965451.1 in Escherichia coli transcription of this gene is enhanced by polyamines