-- dump date 20140620_063330 -- class Genbank::CDS -- table cds_note -- id note YP_001041605.1 CcoN; FixN YP_001041606.1 CcoO; FixO YP_001041613.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_001041614.1 with UspC and UspD is involved in resistance to UV irradiation YP_001041615.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001041619.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001041620.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent YP_001041623.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001041627.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_001041629.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001041630.1 negative modulator of the initiation of chromosome replication YP_001041634.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001041636.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001041639.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001041641.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_001041642.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001041643.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001041645.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001041646.1 Represses the expression of the zwf, eda, glp and gap YP_001041648.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001041659.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_001041661.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001041664.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001041665.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001041666.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_001041667.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_001041668.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_001041674.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001041675.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001041687.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001041692.1 KEGG: shn:Shewana3_4164 type I site-specific deoxyribonuclease, HsdR family; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like YP_001041693.1 PFAM: transposase Tn5, dimerisation domain protein; KEGG: vvy:VV0556 putative Tn5 transposase YP_001041694.1 KEGG: plu:plu3294 regulatory protein recX (oraA protein) YP_001041695.1 KEGG: plu:plu3295 hypothetical protein YP_001041697.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: bhe:BH07080 hypothetical genomic island protein YP_001041698.1 KEGG: rru:Rru_A3195 helix-turn-helix protein, CopG YP_001041700.1 KEGG: psp:PSPPH_A0040 hypothetical protein YP_001041702.1 KEGG: cph:Cpha266_0459 conserved hypothetical protein YP_001041704.1 PFAM: Ig domain protein, group 2 domain protein; KEGG: lil:LA3075 surface protein Lk90-like protein YP_001041705.1 PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: vpa:VP0764 outer membrane protein OmpA YP_001041706.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001041707.1 PFAM: Resolvase, N-terminal domain; KEGG: ppr:PBPRC0052 putative site-specific recombinase YP_001041708.1 PFAM: protein of unknown function DUF1526; KEGG: rru:Rru_A0597 protein of unknown function DUF1526 YP_001041709.1 KEGG: eca:ECA0588 putative plasmid-related protein YP_001041714.1 KEGG: son:SOA0058 hypothetical protein YP_001041715.1 KEGG: net:Neut_0119 conserved hypothetical protein YP_001041716.1 KEGG: bxe:Bxe_A1173 hypothetical protein YP_001041717.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001041718.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001041719.1 KEGG: vfi:VFB13 hypothetical protein YP_001041721.1 KEGG: son:SOA0058 hypothetical protein YP_001041722.1 PFAM: helix-turn-helix domain protein; peptidase S24, S26A and S26B; KEGG: vfi:VFB18 DNA-binding protein RDGA YP_001041723.1 PFAM: Resolvase, N-terminal domain; Resolvase helix-turn-helix domain protein; KEGG: plu:plu3296 hypothetical protein YP_001041724.1 PFAM: transposase Tn3 family protein; KEGG: neu:NE0835 transposase Tn3 family YP_001041725.1 KEGG: pfa:PF11_0207 hypothetical protein YP_001041726.1 TIGRFAM: death-on-curing family protein; PFAM: Death-on-curing protein; KEGG: vch:VCA0475 doc protein YP_001041727.1 KEGG: vch:VCA0474 acetyltransferase, putative YP_001041728.1 KEGG: pfl:PFL_4684 hypothetical protein YP_001041729.1 KEGG: psb:Psyr_1473 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase, type IA, central domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein YP_001041731.1 KEGG: xcv:XCV2288 single-strand DNA-binding protein YP_001041733.1 PFAM: protein of unknown function DUF417; KEGG: vch:VC1587 hypothetical protein YP_001041734.1 KEGG: ppr:PBPRC0031 hypothetical protein YP_001041736.1 PFAM: phage integrase family protein YP_001041737.1 TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: Addiction module toxin, Txe/YoeB; KEGG: yps:pYptb0009 hypothetical protein YP_001041738.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: ppr:PBPRB0955 hypothetical protein YP_001041739.1 TIGRFAM: DNA binding domain, excisionase family; KEGG: mca:MCA2639 hypothetical protein YP_001041740.1 KEGG: mgm:Mmc1_0694 hypothetical protein YP_001041741.1 PFAM: transposase, mutator type; KEGG: son:SO4497 ISSod5, transposase YP_001041743.1 KEGG: shm:Shewmr7_3098 transposase, IS4 family protein YP_001041744.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001041745.1 KEGG: pha:PSHAa0412 hypothetical protein YP_001041746.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001041747.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001041748.1 KEGG: mlo:mll6233 transposase YP_001041749.1 KEGG: shm:Shewmr7_3098 transposase, IS4 family protein YP_001041750.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bma:BMAA1940 transcriptional regulator, LysR family YP_001041751.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001041752.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_3021 integrase, catalytic region YP_001041753.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001041754.1 KEGG: vfi:VF1228 conserved hypothetical protein YP_001041755.1 KEGG: ppr:PBPRB1864 conserved hypothetical protein YP_001041756.1 PFAM: Resolvase, N-terminal domain; KEGG: son:SOA0026 site-specific recombinase, resolvase family YP_001041757.1 KEGG: shn:Shewana3_4160 S-adenosylhomocysteine hydrolase YP_001041758.1 KEGG: shn:Shewana3_4161 conserved hypothetical protein YP_001041759.1 TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; KEGG: yps:YPTB0537 putative type I restriction-modification system, methyltransferase subunit (N-6 DNA methylase) YP_001041760.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_3021 integrase, catalytic region YP_001041761.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001041762.1 PFAM: restriction modification system DNA specificity domain; KEGG: stl:stu0708 type I restriction-modification system specificty subunit YP_001041763.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001041764.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001041765.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001041766.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001041767.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001041768.2 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001041769.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001041770.1 KEGG: shm:Shewmr7_0182 NusG antitermination factor; TIGRFAM: transcription termination/antitermination factor NusG; PFAM: transcription antitermination protein NusG; KOW domain protein; SMART: NGN domain protein; KOW (Kyrpides, Ouzounis, Woese) domain protein YP_001041771.1 binds directly to 23S ribosomal RNA YP_001041772.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001041773.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001041774.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001048407.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001048408.1 KEGG: shm:Shewmr7_0002 DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain YP_001048409.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001048410.1 KEGG: son:SO0011 DNA gyrase subunit B; TIGRFAM: DNA gyrase, B subunit; PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein domain protein; TOPRIM domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein; SMART: DNA topoisomerase II YP_001048411.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: son:SO0012 glutathione S-transferase family protein YP_001048412.1 KEGG: son:SO0714 monoheme cytochrome c YP_001048413.1 PFAM: oxidoreductase, molybdopterin binding; Mo-co oxidoreductase dimerisation domain; KEGG: son:SO0715 oxidoreductase, molybdopterin-binding YP_001048414.1 KEGG: son:SO0716 monoheme cytochrome c, putative YP_001048415.1 KEGG: son:SO0717 monoheme cytochrome c YP_001048416.1 TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; KEGG: saz:Sama_0022 UreA carboxylase YP_001048417.1 PFAM: HDOD; KEGG: shn:Shewana3_0015 putative signal transduction protein YP_001048418.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001048419.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001048420.1 KEGG: shn:Shewana3_0018 DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase YP_001048421.1 PFAM: amidohydrolase; KEGG: shn:Shewana3_0019 amidohydrolase YP_001048422.1 PFAM: WD40 domain protein beta Propeller; KEGG: she:Shewmr4_0011 amidohydrolase YP_001048423.1 KEGG: she:Shewmr4_0012 hypothetical protein YP_001048424.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_001048425.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001048426.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001048427.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_001048428.1 PFAM: protein of unknown function UPF0029; KEGG: she:Shewmr4_0020 protein of unknown function UPF0029 YP_001048429.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: shn:Shewana3_0027 potassium uptake protein, TrkH family YP_001048430.1 KEGG: shn:Shewana3_0028 protoporphyrinogen oxidase YP_001048431.1 PFAM: regulatory protein, ArsR; KEGG: shn:Shewana3_0029 transcriptional regulator, ArsR family YP_001048432.1 KEGG: shn:Shewana3_0030 protoporphyrinogen oxidase YP_001048433.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: shm:Shewmr7_0023 potassium uptake protein, TrkH family YP_001048434.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001048435.1 TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: shn:Shewana3_0033 sun protein YP_001048436.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: shm:Shewmr7_0026 methionyl-tRNA formyltransferase YP_001048437.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001048438.1 PFAM: Peptidoglycan-binding LysM; KEGG: shm:Shewmr7_0028 peptidoglycan-binding LysM YP_001048439.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: son:SO0034 DNA processing protein DprA, putative YP_001048440.1 PFAM: protein of unknown function DUF494; KEGG: son:SO0035 Smg protein YP_001048441.1 PFAM: DNA topoisomerase, type IA, zn finger domain protein; KEGG: shm:Shewmr7_0031 DNA topoisomerase, type IA, zn finger domain protein YP_001048442.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: son:SO0037 Sua5/YciO/YrdC/YwlC family protein YP_001048443.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001048444.1 PFAM: globin; KEGG: son:SO0039 hypothetical globin YP_001048445.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001048446.1 PFAM: protein of unknown function DUF1488; KEGG: son:SO0041 hypothetical protein YP_001048447.1 KEGG: shn:Shewana3_0045 carbonic anhydrase, family 3 YP_001048448.1 KEGG: shn:Shewana3_4120 diguanylate phosphodiesterase; TIGRFAM: PAS sensor protein; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001048449.1 PFAM: alpha/beta hydrolase fold; KEGG: shn:Shewana3_4119 alpha/beta hydrolase fold YP_001048450.1 PFAM: protein of unknown function DUF885; KEGG: shn:Shewana3_4118 protein of unknown function DUF885 YP_001048451.1 catalyzes the formation of inosine from adenosine YP_001048452.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001048453.1 KEGG: shn:Shewana3_4115 conserved hypothetical protein YP_001048454.1 PFAM: protein of unknown function DUF414; KEGG: shn:Shewana3_4114 protein of unknown function DUF414 YP_001048455.1 KEGG: son:SO4727 hypothetical protein YP_001048456.1 PFAM: cytochrome c, class I; KEGG: shn:Shewana3_4111 cytochrome c, class I YP_001048457.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001048458.1 KEGG: shn:Shewana3_4109 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2 YP_001048459.1 PFAM: ThiJ/PfpI domain protein; KEGG: shn:Shewana3_4108 ThiJ/PfpI domain protein YP_001048460.1 PFAM: Rhomboid family protein; KEGG: shn:Shewana3_4107 rhomboid family protein YP_001048461.1 PFAM: Rhodanese domain protein; KEGG: shn:Shewana3_4106 rhodanese domain protein YP_001048462.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_001048463.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_001048464.1 PFAM: regulatory protein, TetR; KEGG: son:SO4675 transcriptional regulator, TetR family YP_001048465.1 PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain protein; KEGG: shn:Shewana3_4102 coproporphyrinogen oxidase YP_001048466.1 catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position YP_001048467.1 PFAM: glycosyl transferase, family 9; KEGG: son:SO4678 heptosyl transferase, glycosyltransferase family 9 protein YP_001048468.1 KEGG: saz:Sama_0103 conserved hypothetical protein YP_001048469.1 KEGG: rba:RB9243 hypothetical protein-putative glycosyltransferase YP_001048470.1 PFAM: glycosyl transferase, family 2; KEGG: sdn:Sden_0205 glycosyl transferase, family 2 YP_001048471.1 PFAM: glycosyl transferase, group 1; KEGG: pha:PSHAa2452 glycosyl transferase YP_001048472.1 PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: saz:Sama_2261 UDP-N-acetylglucosamine 2-epimerase YP_001048473.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001048474.1 KEGG: shn:Shewana3_4090 conserved hypothetical protein YP_001048475.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: shm:Shewmr7_3979 UDP-glucuronate 5'-epimerase YP_001048476.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; KEGG: son:SO4687 UDP-glucose 6-dehydrogenase YP_001048477.1 PFAM: glycosyl transferase, family 2; KEGG: she:Shewmr4_3884 glycosyl transferase, family 2 YP_001048478.1 KEGG: shn:Shewana3_4086 conserved hypothetical protein YP_001048479.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001048480.1 KEGG: shn:Shewana3_4083 conserved hypothetical protein YP_001048481.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001048482.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin binding domain; molybdopterin-guanine dinucleotide biosynthesis MobB region; MoeA domain protein, domain I and II; MoeA domain protein, domain IV; KEGG: shn:Shewana3_4081 molybdopterin-guanine dinucleotide biosynthesis protein B YP_001048483.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein A; KEGG: son:SO4722 molybdopterin-guanine dinucleotide biosynthesis protein YP_001048484.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shn:Shewana3_4079 ABC transporter related YP_001048485.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: she:Shewmr4_3875 binding-protein-dependent transport systems inner membrane component YP_001048486.1 KEGG: shn:Shewana3_4077 extracellular solute-binding protein, family 1 YP_001048487.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_3966 two component, sigma54 specific, transcriptional regulator, fis family YP_001048488.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: shn:Shewana3_4075 ATP-binding region, ATPase domain protein domain protein YP_001048489.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_3871 acetyltransferase, GNAT family YP_001048490.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: son:SO4715 hypothetical protein YP_001048491.1 KEGG: she:Shewmr4_3869 hypothetical protein YP_001048492.1 TIGRFAM: isochorismate synthases; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: she:Shewmr4_3868 isochorismate synthases YP_001048493.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_3867 TonB-dependent receptor, plug YP_001048494.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_3959 ABC transporter related YP_001048495.1 PFAM: cobalt transport protein; KEGG: she:Shewmr4_3865 cobalt transport protein YP_001048496.1 KEGG: shm:Shewmr7_3957 hypothetical protein YP_001048497.1 KEGG: she:Shewmr4_3863 hypothetical protein YP_001048498.1 KEGG: shm:Shewmr7_3956 hypothetical protein YP_001048499.1 KEGG: shm:Shewmr7_3955 hypothetical protein YP_001048500.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: son:SO4711 HD domain protein YP_001048501.1 PFAM: Paraquat-inducible protein A; KEGG: shm:Shewmr7_3953 paraquat-inducible protein A YP_001048502.1 KEGG: shn:Shewana3_4067 conserved hypothetical protein YP_001048503.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: shn:Shewana3_4066 heavy metal efflux pump, CzcA family YP_001048504.1 KEGG: shn:Shewana3_4065 hypothetical protein YP_001048505.1 KEGG: shm:Shewmr7_3949 hypothetical protein YP_001048506.1 SMART: regulatory protein, LuxR; KEGG: shn:Shewana3_4063 transcriptional regulator, LuxR family YP_001048507.1 KEGG: shm:Shewmr7_3947 hypothetical protein YP_001048508.1 PFAM: conserved hypothetical protein 698; KEGG: shm:Shewmr7_3946 conserved hypothetical protein 698 YP_001048509.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001048510.1 PFAM: helix-turn-helix domain protein; KEGG: shm:Shewmr7_3944 transcriptional regulator, XRE family YP_001048511.1 KEGG: pha:PSHAa0008 hypothetical protein YP_001048512.1 KEGG: sdn:Sden_2357 hypothetical protein YP_001048513.1 PFAM: PepSY-associated TM helix domain protein; KEGG: shm:Shewmr7_1218 PepSY-associated TM helix domain protein YP_001048514.1 KEGG: bbr:BB3605 putative iron uptake protein YP_001048515.1 PFAM: acriflavin resistance protein; KEGG: csa:Csal_2405 acriflavin resistance protein YP_001048516.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: hne:HNE_2191 efflux transporter, RND family, MFP subunit YP_001048517.1 KEGG: xcv:XCV0280 putative secreted protein YP_001048518.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pen:PSEEN2529 TonB-dependent siderophore receptor YP_001048519.1 TIGRFAM: gamma-glutamyl phosphate reductase; KEGG: shm:Shewmr7_3942 gamma-glutamyl phosphate reductase YP_001048520.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001048521.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: she:Shewmr4_3847 sodium/proline symporter YP_001048522.1 PFAM: Fusaric acid resistance protein conserved region; KEGG: pha:PSHAa1079 hypothetical protein ; membrane protein YP_001048523.1 PFAM: secretion protein HlyD family protein; KEGG: abo:ABO_1136 efflux transporter, membrane fusion protein, putative YP_001048524.1 PFAM: protein of unknown function DUF1656; KEGG: pha:PSHAa1077 hypothetical protein YP_001048525.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001048526.1 KEGG: son:SO4701 hypothetical protein YP_001048527.1 KEGG: son:SO4700 hypothetical protein YP_001048528.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: son:SO4699 oligopeptidase A YP_001048529.1 KEGG: shm:Shewmr7_3934 hypothetical protein YP_001048530.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: she:Shewmr4_3840 glutathione S-transferase, N-terminal domain protein YP_001048531.1 KEGG: shm:Shewmr7_3932 conserved hypothetical 3-methyladenine DNA glycosylase YP_001048532.1 KEGG: shn:Shewana3_4047 conserved hypothetical protein YP_001048533.1 KEGG: aeh:Mlg_2336 hypothetical protein YP_001048534.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001048535.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001048536.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_3021 integrase, catalytic region YP_001048537.1 PFAM: lipolytic enzyme, G-D-S-L family; KEGG: cvi:CV2266 probable SPI2 translocated effector YP_001048538.1 KEGG: vpa:VPA1321 cytotoxic necrotizing factor YP_001048539.1 TIGRFAM: transcription elongation factor GreB; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: she:Shewmr4_3810 transcription elongation factor GreB YP_001048540.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase, RNase H domain protein fold; KEGG: son:SO4629 hypothetical protein YP_001048541.1 PFAM: sulfatase; KEGG: son:SO4628 sulfatase YP_001048542.1 KEGG: she:Shewmr4_3807 hypothetical protein YP_001048543.1 TIGRFAM: bioH protein; PFAM: alpha/beta hydrolase fold; KEGG: shn:Shewana3_4010 BioH protein YP_001048544.1 KEGG: shm:Shewmr7_3881 competence protein ComF YP_001048545.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_001048546.1 PFAM: peptidase S15; peptidase S9, prolyl oligopeptidase active site domain protein; phospholipase/Carboxylesterase; KEGG: she:Shewmr4_3803 peptidase S9, prolyl oligopeptidase active site domain protein YP_001048547.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: she:Shewmr4_3802 MATE efflux family protein YP_001048548.1 PFAM: polysaccharide deacetylase; KEGG: she:Shewmr4_3801 polysaccharide deacetylase YP_001048549.1 PFAM: electron transport protein SCO1/SenC; KEGG: shn:Shewana3_3999 electron transport protein SCO1/SenC YP_001048550.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001048551.1 PFAM: cytochrome oxidase assembly; KEGG: son:SO4613 cytochrome oxidase assembly protein, putative YP_001048552.1 KEGG: son:SO4612 hypothetical protein YP_001048553.1 KEGG: she:Shewmr4_3796 hypothetical protein YP_001048554.1 PFAM: cytochrome c oxidase, subunit III; KEGG: shm:Shewmr7_3867 cytochrome c oxidase, subunit III YP_001048555.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_001048556.1 PFAM: cytochrome c oxidase, subunit I; KEGG: son:SO4607 cytochrome c oxidase, subunit I YP_001048557.1 PFAM: cytochrome c oxidase, subunit II; cytochrome c, class I; cytochrome C oxidase subunit II, transmembrane region; KEGG: shm:Shewmr7_3864 cytochrome c oxidase, subunit II YP_001048558.1 KEGG: shm:Shewmr7_3863 hypothetical protein YP_001048559.1 Represses a number of genes involved in the response to DNA damage YP_001048560.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_001048561.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; KEGG: she:Shewmr4_3787 aromatic amino acid transporter YP_001048562.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: shm:Shewmr7_3859 glyoxalase/bleomycin resistance protein/dioxygenase YP_001048563.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shn:Shewana3_3985 methyl-accepting chemotaxis sensory transducer YP_001048564.1 PFAM: ribonuclease T2; KEGG: son:SO4599 ribonuclease, T2 family YP_001048565.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: son:SOA0153 heavy metal efflux pump, CzcA family YP_001048566.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: son:SOA0154 heavy metal efflux protein, putative YP_001048567.1 KEGG: son:SOA0155 hypothetical protein YP_001048568.1 KEGG: son:SOA0156 hypothetical protein YP_001048569.1 KEGG: son:SOA0157 hypothetical protein YP_001048570.1 KEGG: son:SOA0158 hypothetical protein YP_001048571.1 PFAM: NapC/NirT cytochrome c domain protein; KEGG: saz:Sama_3471 tetraheme cytochrome c YP_001048572.1 PFAM: protein of unknown function DUF1145; KEGG: shn:Shewana3_3974 protein of unknown function DUF1145 YP_001048573.1 TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: she:Shewmr4_3775 putative methyltransferase YP_001048574.1 KEGG: shm:Shewmr7_3847 signal recognition particle-docking protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54, G- domain; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase YP_001048575.1 KEGG: shn:Shewana3_3971 cell division ATP-binding protein FtsE; TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: AAA ATPase YP_001048576.1 PFAM: protein of unknown function DUF214; KEGG: son:SO4584 cell division ABC transporter, permease protein FtsX YP_001048577.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001048578.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: son:SO4576 O-succinylbenzoic acid--CoA ligase YP_001048579.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_001048580.1 PFAM: alpha/beta hydrolase fold; KEGG: shn:Shewana3_3966 alpha/beta hydrolase fold YP_001048581.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_001048582.1 PFAM: regulatory protein, LysR; KEGG: shn:Shewana3_3964 transcriptional regulator, LysR family YP_001048583.1 KEGG: shn:Shewana3_3963 hypothetical protein YP_001048584.1 KEGG: she:Shewmr4_3764 formate-dependent nitrite reductase YP_001048585.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: she:Shewmr4_3763 twin-arginine translocation pathway signal YP_001048586.1 PFAM: Polysulphide reductase, NrfD; KEGG: shn:Shewana3_3960 polysulphide reductase, NrfD YP_001048587.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: shn:Shewana3_3959 transcriptional regulator, AsnC family YP_001048588.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_001048589.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: shm:Shewmr7_3832 TonB family protein YP_001048590.1 PFAM: HDOD; KEGG: shn:Shewana3_3956 putative signal transduction protein YP_001048591.1 PFAM: protein of unknown function DUF1332; KEGG: son:SO4562 hypothetical protein YP_001048592.1 KEGG: she:Shewmr4_3756 hypothetical protein YP_001048593.1 KEGG: shm:Shewmr7_3828 hypothetical protein YP_001048594.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: she:Shewmr4_3754 Sel1 domain protein repeat-containing protein YP_001048595.1 KEGG: shm:Shewmr7_3826 hypothetical protein YP_001048596.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_3825 methyl-accepting chemotaxis sensory transducer YP_001048597.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_3825 methyl-accepting chemotaxis sensory transducer YP_001048598.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_3824 transcriptional regulator, LysR family YP_001048599.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_3750 drug resistance transporter, Bcr/CflA subfamily YP_001048600.1 KEGG: sfr:Sfri_3123 hypothetical protein YP_001048601.1 PFAM: DTW domain containing protein; KEGG: shn:Shewana3_3947 DTW domain containing protein YP_001048602.1 KEGG: son:SO4552 sensory box protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001048603.1 KEGG: she:Shewmr4_3747 hypothetical protein YP_001048604.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shn:Shewana3_3944 methyltransferase type 11 YP_001048605.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: hch:HCH_05533 uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides YP_001048606.1 PFAM: NIPSNAP family containing protein; KEGG: hch:HCH_05534 hypothetical protein YP_001048607.1 PFAM: regulatory protein, ArsR; KEGG: hch:HCH_05536 predicted transcriptional regulator YP_001048608.1 KEGG: sfr:Sfri_0292 hypothetical protein YP_001048609.1 KEGG: shn:Shewana3_3941 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001048610.1 PFAM: peptidase M16 domain protein; KEGG: son:SO4537.2 hypothetical Zn-dependent peptidase YP_001048611.1 PFAM: peptidase M16 domain protein; KEGG: shm:Shewmr7_3814 peptidase M16 domain protein YP_001048612.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: shm:Shewmr7_3813 peptidase S9, prolyl oligopeptidase active site domain protein YP_001048613.1 KEGG: shn:Shewana3_3937 conserved hypothetical protein YP_001048614.1 TIGRFAM: RNA methyltransferase, TrmH family, group 2; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: shn:Shewana3_3934 RNA methyltransferase, TrmH family, group 2 YP_001048615.1 KEGG: son:SO4528 hypothetical protein YP_001048616.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: shm:Shewmr7_3806 protein of unknown function DUF6, transmembrane YP_001048617.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_3805 transcriptional regulator, LysR family YP_001048618.1 PFAM: Patatin; KEGG: shn:Shewana3_3931 patatin YP_001048619.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO4524 transcriptional regulator, LysR family YP_001048620.1 IrgA; binds ferric enterobactin; irgA gene expression is repressed by Fur and induced by the divergently transcribed upstream gene irgB; outer membrane protein; involved in iron metabolism YP_001048621.1 KEGG: shn:Shewana3_3927 conserved hypothetical protein YP_001048622.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001048623.1 PFAM: Bile acid:sodium symporter; KEGG: son:SO4519 sodium-dependent transporter YP_001048624.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: hch:HCH_06539 FOG: TPR repeat, SEL1 subfamily YP_001048625.1 KEGG: abo:ABO_1732 hypothetical protein YP_001048626.1 KEGG: abo:ABO_1733 hypothetical protein YP_001048627.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001048628.1 PFAM: Heme exporter protein D (CcmD); KEGG: shn:Shewana3_0228 heme exporter protein D (CcmD) YP_001048629.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein; KEGG: son:SO0261 heme exporter protein CcmC YP_001048630.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: son:SO0262 heme exporter protein CcmB YP_001048631.1 ATP-binding protein; required for proper cytochrome c maturation YP_001048632.1 PFAM: cytochrome c, class I; KEGG: shn:Shewana3_0232 cytochrome c, class I YP_001048633.1 SMART: Tetratricopeptide domain protein; KEGG: she:Shewmr4_0233 TPR repeat-containing protein YP_001048634.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: shm:Shewmr7_0229 cytochrome c-type biogenesis protein CcmF YP_001048635.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: son:SO0267 thiol:disulfide interchange protein DsbE YP_001048636.1 PFAM: cytochrome C biogenesis protein; KEGG: shn:Shewana3_0236 cytochrome c biogenesis protein YP_001048637.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shn:Shewana3_0237 redoxin domain protein YP_001048638.1 KEGG: shm:Shewmr7_3783 hypothetical protein YP_001048639.1 KEGG: son:SO4490 hypothetical protein YP_001048640.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO4489 acetyltransferase, GNAT family YP_001048641.1 PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: son:SO4488 sensor histidine kinase YP_001048642.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shn:Shewana3_0241 two component transcriptional regulator, winged helix family YP_001048643.1 PFAM: Propeptide, PepSY amd peptidase M4; KEGG: shn:Shewana3_0242 propeptide, PepSY amd peptidase M4 YP_001048644.1 KEGG: shn:Shewana3_0243 diheme cytochrome c YP_001048645.1 PFAM: cytochrome c, monohaem; KEGG: shn:Shewana3_0244 cytochrome c-type protein Shp YP_001048646.1 PFAM: cytochrome B561; KEGG: she:Shewmr4_0244 cytochrome b561 YP_001048647.1 KEGG: shn:Shewana3_0246 conserved hypothetical protein YP_001048648.1 KEGG: son:SO4481 hypothetical protein YP_001048649.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shn:Shewana3_0248 transcriptional regulator, LysR family YP_001048650.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: shm:Shewmr7_3773 short-chain dehydrogenase/reductase SDR YP_001048651.1 PFAM: aldehyde dehydrogenase; KEGG: son:SO4480 aldehyde dehydrogenase YP_001048652.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3771 GAF modulated sigma54 specific transcriptional regulator, fis family YP_001048653.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: she:Shewmr4_2154 alcohol dehydrogenase, zinc-binding domain protein YP_001048654.1 KEGG: shm:Shewmr7_2230 flavocytochrome c YP_001048655.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001048656.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001048657.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: shm:Shewmr7_2230 flavocytochrome c YP_001048658.1 KEGG: shm:Shewmr7_2229 tetraheme cytochrome c YP_001048659.1 KEGG: shm:Shewmr7_2228 hypothetical protein YP_001048660.1 KEGG: shm:Shewmr7_2227 hypothetical protein YP_001048661.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2226 transcriptional regulator, LysR family YP_001048662.1 KEGG: shm:Shewmr7_2225 putative transcriptional regulator, TetR family YP_001048663.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4478 sensor protein CpxA YP_001048664.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shn:Shewana3_0253 two component transcriptional regulator, winged helix family YP_001048665.1 PFAM: protein of unknown function, Spy-related; KEGG: she:Shewmr4_0253 protein of unknown function, Spy-related YP_001048666.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: she:Shewmr4_0254 cation diffusion facilitator family transporter YP_001048667.1 KEGG: she:Shewmr4_0255 hypothetical protein YP_001048668.1 KEGG: she:Shewmr4_0257 nitrogen metabolism transcriptional regulator, NtrC, fis family; TIGRFAM: nitrogen regulation protein NR(I); PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001048669.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; KEGG: shn:Shewana3_0259 signal transduction histidine kinase, nitrogen specific, NtrB YP_001048670.1 KEGG: son:SO4470 hypothetical protein YP_001048671.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: sdn:Sden_1385 glutathione S-transferase-like protein YP_001048672.1 PFAM: ThiJ/PfpI domain protein; KEGG: sfr:Sfri_0805 ThiJ/PfpI domain protein YP_001048673.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: shn:Shewana3_0261 iron-containing alcohol dehydrogenase YP_001048674.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_3760 transcriptional regulator, TetR family YP_001048675.1 PFAM: protein of unknown function DUF1255; KEGG: shm:Shewmr7_3759 protein of unknown function DUF1255 YP_001048676.1 PFAM: chemotaxis sensory transducer; KEGG: shn:Shewana3_0264 methyl-accepting chemotaxis sensory transducer YP_001048677.1 PFAM: protein of unknown function DUF323; Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_3757 protein of unknown function DUF323 YP_001048678.1 KEGG: shm:Shewmr7_3756 hypothetical protein YP_001048679.1 KEGG: son:SO4461 hypothetical protein YP_001048680.1 PFAM: PfkB domain protein; KEGG: son:SO4458 carbohydrate kinase, PfkB family YP_001048681.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: she:Shewmr4_0268 diguanylate cyclase YP_001048682.1 PFAM: 3-alpha; MOSC domain containing protein; KEGG: she:Shewmr4_0269 MOSC domain containing protein YP_001048683.1 KEGG: shn:Shewana3_0271 conserved hypothetical protein YP_001048684.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_3750 methyl-accepting chemotaxis sensory transducer YP_001048685.1 PFAM: FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase; KEGG: shn:Shewana3_0273 electron transfer flavoprotein-ubiquinone oxidoreductase YP_001048686.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001048687.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001048688.1 TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: son:SO4450 molybdenum cofactor biosynthesis protein D YP_001048689.1 PFAM: molybdopterin biosynthesis MoaE; KEGG: she:Shewmr4_0276 molybdopterin biosynthesis MoaE YP_001048690.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; KEGG: she:Shewmr4_0277 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_001048691.1 TIGRFAM: molybdate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_3743 molybdate ABC transporter, inner membrane subunit YP_001048692.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shn:Shewana3_0280 ABC transporter related YP_001048693.1 KEGG: son:SO4430 hypothetical protein YP_001048694.1 KEGG: shn:Shewana3_0281 conserved hypothetical protein YP_001048695.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shn:Shewana3_0282 two component transcriptional regulator, winged helix family YP_001048696.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4427 sensor histidine kinase YP_001048697.1 TIGRFAM: pseudouridine synthase Rlu family protein, TIGR01621; PFAM: pseudouridine synthase; KEGG: shn:Shewana3_0284 pseudouridine synthase Rlu family protein, TIGR01621 YP_001048698.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO4425 GGDEF family protein YP_001048699.1 PFAM: protein of unknown function UPF0057; KEGG: shn:Shewana3_0285 protein of unknown function UPF0057 YP_001048700.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_0286 TonB-dependent receptor YP_001048701.1 KEGG: shm:Shewmr7_3732 hypothetical protein YP_001048702.1 PFAM: peptidase M23B; KEGG: son:SO4420 peptidase, M23/M37 family YP_001048703.1 KEGG: shn:Shewana3_0289 conserved hypothetical protein YP_001048704.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_001048705.1 KEGG: son:SO4414 hypothetical protein YP_001048706.1 PFAM: aminotransferase, class V; KEGG: shn:Shewana3_0295 aminotransferase, class V YP_001048707.1 PFAM: sodium:dicarboxylate symporter; KEGG: shm:Shewmr7_3722 sodium:dicarboxylate symporter YP_001048708.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_001048709.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; KEGG: sdn:Sden_3455 GTP-binding protein TypA YP_001048710.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO4407 GGDEF family protein YP_001048711.1 PFAM: sulfatase; KEGG: lbl:LBL_1125 alkaline phosphatase YP_001048712.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_3712 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001048713.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: aha:AHA_1948 2OG-Fe(II) oxygenase superfamily protein YP_001048714.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: aha:AHA_1947 methionine gamma-lyase YP_001048715.1 KEGG: shn:Shewana3_0309 conserved hypothetical protein YP_001048716.1 KEGG: she:Shewmr4_0315 hypothetical protein YP_001048717.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_001048718.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO4400 proline iminopeptidase, putative YP_001048719.1 KEGG: son:SO4399 hypothetical protein YP_001048720.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001048721.1 TIGRFAM: thioesterase domain, putative; KEGG: she:Shewmr4_0320 thioesterase domain, putative YP_001048722.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_001048723.1 KEGG: son:SO4395 hypothetical protein YP_001048724.1 PFAM: Rhodanese domain protein; KEGG: shn:Shewana3_0318 rhodanese domain protein YP_001048725.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; KEGG: she:Shewmr4_0324 transcriptional regulator, XRE family with cupin sensor YP_001048726.1 TIGRFAM: benzoate transporter; PFAM: Benzoate membrane transport protein; Xanthine/uracil/vitamin C permease; KEGG: shm:Shewmr7_3699 benzoate transporter YP_001048727.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_3696 GCN5-related N-acetyltransferase YP_001048728.1 KEGG: shn:Shewana3_0325 conserved hypothetical protein YP_001048729.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001048730.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001048731.1 KEGG: son:SO4381 thioester dehydrase family protein YP_001048732.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001048733.1 KEGG: shn:Shewana3_0330 conserved hypothetical protein YP_001048734.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; tryptophan halogenase; KEGG: shm:Shewmr7_3686 monooxygenase, FAD-binding protein YP_001048735.1 KEGG: son:SO4377 hypothetical protein YP_001048736.1 KEGG: shm:Shewmr7_3684 hypothetical protein YP_001048737.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_3683 thioesterase superfamily protein YP_001048738.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: she:Shewmr4_0344 histidine ammonia-lyase YP_001048739.1 PFAM: glycosyl transferase, family 2; lipid A biosynthesis acyltransferase; KEGG: she:Shewmr4_0345 glycosyl transferase, family 2 YP_001048740.1 KEGG: son:SO4372 thioester dehydrase family protein YP_001048741.1 KEGG: shn:Shewana3_0338 aconitate hydratase YP_001048742.1 KEGG: shm:Shewmr7_3678 hypothetical protein YP_001048743.1 carries the fatty acid chain in fatty acid biosynthesis YP_001048744.1 KEGG: shn:Shewana3_0344 acyl carrier protein, putative YP_001048745.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: she:Shewmr4_0351 phospholipid/glycerol acyltransferase YP_001048746.1 KEGG: son:SO4366 hypothetical protein YP_001048747.1 KEGG: son:SO4365 hypothetical protein YP_001048748.1 catalyzes branch migration in Holliday junction intermediates YP_001048749.1 PFAM: regulatory protein, LuxR; response regulator receiver; Bacterio-opsin activator, HTH domain protein; Sigma-70, region 4 type 2; KEGG: son:SO0351 DNA-binding response regulator, LuxR family YP_001048750.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region; KEGG: shn:Shewana3_3817 putative signal transduction histidine kinase YP_001048751.1 PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: son:SO0353 TPR domain protein YP_001048752.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: shm:Shewmr7_0325 Na+/Ca+ antiporter, CaCA family YP_001048753.1 PFAM: AMP-dependent synthetase and ligase; KEGG: son:SO0355 AMP-binding protein YP_001048754.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: shn:Shewana3_3813 putative endoribonuclease L-PSP YP_001048755.1 KEGG: son:SO0359 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; metal-dependent phosphohydrolase, HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase, HD region YP_001048756.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001048757.1 Essential for recycling GMP and indirectly, cGMP YP_001048758.1 KEGG: shn:Shewana3_3809 conserved hypothetical protein YP_001048759.1 KEGG: she:Shewmr4_3611 hypothetical protein YP_001048760.1 PFAM: aminoglycoside phosphotransferase; KEGG: shm:Shewmr7_0333 aminoglycoside phosphotransferase YP_001048761.1 PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_3609 twin-arginine translocation pathway signal YP_001048762.1 KEGG: sfr:Sfri_3844 hypothetical protein YP_001048763.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: shm:Shewmr7_0336 filamentation induced by cAMP protein Fic YP_001048764.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; SMART: DEAD-like helicases-like; KEGG: son:SO0368 helicase YP_001048765.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shn:Shewana3_3800 transcriptional regulator, LysR family YP_001048766.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_001048767.1 PFAM: helix-hairpin-helix motif; ERCC4 domain protein; SMART: Helix-hairpin-helix DNA-binding, class 1; KEGG: sdn:Sden_0291 ERCC4 YP_001048768.1 KEGG: shm:Shewmr7_3560 hypothetical protein YP_001048769.1 PFAM: helix-turn-helix domain protein; KEGG: sdn:Sden_0306 transciptional regulator YP_001048770.1 PFAM: YicC N-terminal domain protein; domain of unknown function DUF1732; KEGG: shm:Shewmr7_0351 hypothetical protein YP_001048771.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001048772.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001048773.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001048774.1 PFAM: peptidase S15; peptidase S9, prolyl oligopeptidase active site domain protein; dienelactone hydrolase; KEGG: shm:Shewmr7_0355 peptidase S9, prolyl oligopeptidase active site domain protein YP_001048775.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_001048776.1 catalyzes the formation of dUMP from dUTP YP_001048777.1 KEGG: shn:Shewana3_3771 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein YP_001048778.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001048779.1 required for 70S ribosome assembly YP_001048780.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001048781.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_001048782.1 KEGG: son:SO4244 hypothetical protein YP_001048783.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6, transmembrane; KEGG: son:SO4243 rarD protein YP_001048784.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: she:Shewmr4_3591 uncharacterized domain 1 YP_001048785.1 KEGG: shn:Shewana3_3763 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001048786.1 SMART: Tetratricopeptide domain protein; KEGG: she:Shewmr4_3589 response regulator receiver protein YP_001048787.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001048788.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001048789.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001048790.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001048791.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: shn:Shewana3_3757 membrane protein involved in aromatic hydrocarbon degradation YP_001048792.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase, FGGY; KEGG: shn:Shewana3_3756 glycerol kinase YP_001048793.1 KEGG: shm:Shewmr7_0374 hypothetical protein YP_001048794.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001048795.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: she:Shewmr4_3578 S-adenosyl-methyltransferase MraW YP_001048796.1 PFAM: cell division protein FtsL; KEGG: she:Shewmr4_3577 cell division protein FtsL YP_001048797.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: shn:Shewana3_3749 succinate dehydrogenase (ubiquinone) YP_001048798.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001048799.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: son:SO4223 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanine ligase YP_001048800.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001048801.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001048802.1 TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: shn:Shewana3_3744 cell division protein FtsW YP_001048803.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001048804.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001048805.1 PFAM: cell division protein FtsQ; Polypeptide-transport-associated domain protein, FtsQ-type; KEGG: son:SO4217 cell division protein FtsQ YP_001048806.1 PFAM: cell division protein FtsA; KEGG: shn:Shewana3_3740 cell division protein FtsA YP_001048807.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001048808.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001048809.1 KEGG: shn:Shewana3_3737 conserved hypothetical protein YP_001048810.1 PFAM: peptidase M23B; KEGG: shn:Shewana3_3736 peptidase M23B YP_001048811.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001048812.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_001048814.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001048815.1 KEGG: shm:Shewmr7_3589 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; PFAM: PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001048816.1 PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: son:SO0437 sensory box protein YP_001048817.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: shn:Shewana3_0437 short-chain dehydrogenase/reductase SDR YP_001048818.1 KEGG: son:SO0439 hypothetical protein YP_001048819.1 KEGG: son:SO0440 hypothetical protein YP_001048820.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001048821.1 involved in de novo purine biosynthesis YP_001048822.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_001048823.1 PFAM: permease; KEGG: she:Shewmr4_0447 permease YP_001048824.1 PFAM: band 7 protein; KEGG: shn:Shewana3_0444 band 7 protein YP_001048825.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: ppr:PBPRB1023 hypothetical ribosomal small subunit pseudouridine synthase A YP_001048826.1 PFAM: major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_3577 major facilitator superfamily MFS_1 YP_001048827.1 KEGG: shm:Shewmr7_3575 hypothetical protein YP_001048828.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: she:Shewmr4_0455 anion transporter YP_001048829.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: shm:Shewmr7_3573 thioredoxin YP_001048830.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO0453 peptidyl-prolyl cis-trans isomerase FkbP YP_001048831.1 KEGG: she:Shewmr4_0458 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein YP_001048832.1 KEGG: shn:Shewana3_0455 conserved hypothetical protein YP_001048833.1 TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: she:Shewmr4_0460 TRAP transporter, 4TM/12TM fusion protein YP_001048834.1 TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: shn:Shewana3_0457 response regulator receiver protein YP_001048835.1 KEGG: son:SO0458 hypothetical protein YP_001048836.1 PFAM: protein of unknown function DUF853, NPT hydrolase putative; KEGG: shn:Shewana3_0459 protein of unknown function DUF853, NPT hydrolase putative YP_001048837.1 KEGG: son:SO0461 hypothetical protein YP_001048838.1 KEGG: she:Shewmr4_0465 hypothetical protein YP_001048839.1 PFAM: protein of unknown function, zinc metallopeptidase putative; KEGG: shn:Shewana3_0462 protein of unknown function, zinc metallopeptidase putative YP_001048840.1 PFAM: NUDIX hydrolase; KEGG: son:SO0464 MutT/nudix family protein YP_001048841.1 KEGG: psb:Psyr_3988 hypothetical protein YP_001048842.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_001048843.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_001048844.1 periplasmic sensory protein associated with the TorRS two-component regulatory system YP_001048845.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mca:MCA2808 hypothetical protein YP_001048846.1 PFAM: dihydroorotate dehydrogenase; 2-nitropropane dioxygenase, NPD; KEGG: shn:Shewana3_0474 2-nitropropane dioxygenase, NPD YP_001048847.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shm:Shewmr7_3552 redoxin domain protein YP_001048848.1 PFAM: protein of unknown function UPF0118; KEGG: shn:Shewana3_0477 protein of unknown function UPF0118 YP_001048849.1 KEGG: shm:Shewmr7_3550 putative mitomycin resistance protein YP_001048850.1 KEGG: son:SO0474 hypothetical protein YP_001048851.1 PFAM: peptidase M13, neprilysin; peptidase M13; KEGG: she:Shewmr4_0499 endothelin-converting enzyme 1 YP_001048852.1 PFAM: fatty acid cistrans isomerase; KEGG: shm:Shewmr7_3530 fatty acid cistrans isomerase YP_001048853.1 KEGG: son:SO0492 hypothetical flavoprotein oxygenase YP_001048854.1 KEGG: she:Shewmr4_0503 hypothetical protein YP_001048855.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001048856.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001048857.1 KEGG: bbr:BB1936 adhesin YP_001048858.1 KEGG: son:SO0492 hypothetical flavoprotein oxygenase YP_001048859.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfr:Sfri_4014 transposase IS3/IS911 family protein YP_001048860.1 PFAM: Integrase, catalytic region; KEGG: sfr:Sfri_4013 integrase, catalytic region YP_001048861.1 PFAM: transposase, IS4 family protein; KEGG: she:Shewmr4_2240 transposase, IS4 family protein YP_001048862.1 KEGG: ppr:PBPRA1420 hypothetical protein YP_001048863.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_001048864.1 TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: shn:Shewana3_0506 UbiD family decarboxylases YP_001048865.1 KEGG: she:Shewmr4_0507 hypothetical protein YP_001048866.1 PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_0508 major facilitator superfamily MFS_1 YP_001048867.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR; KEGG: shn:Shewana3_0509 short-chain dehydrogenase/reductase SDR YP_001048868.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: son:SO0511 acetyl-CoA carboxylase, biotin carboxyl carrier protein YP_001048869.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001048870.1 PFAM: Class I peptide chain release factor; KEGG: shn:Shewana3_0512 class I peptide chain release factor YP_001048871.1 KEGG: son:SO0514 hypothetical protein YP_001048872.1 KEGG: shn:Shewana3_0514 conserved hypothetical protein YP_001048873.1 KEGG: she:Shewmr4_0515 hypothetical protein YP_001048874.1 KEGG: shm:Shewmr7_3515 outer membrane efflux protein YP_001048875.1 KEGG: son:SO0518 outer membrane efflux family protein, putative YP_001048876.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO0519 cation efflux protein, putative YP_001048877.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: shn:Shewana3_0518 heavy metal efflux pump, CzcA family YP_001048878.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: son:SO0521 hypothetical protein YP_001048879.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_001048880.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shn:Shewana3_0521 transcriptional regulator, LysR family YP_001048881.1 PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_3509 secretion protein HlyD family protein YP_001048882.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_3508 drug resistance transporter, EmrB/QacA subfamily YP_001048883.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_0525 GCN5-related N-acetyltransferase YP_001048884.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: son:SO0527 hypothetical protein YP_001048885.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: shm:Shewmr7_3501 radical SAM domain protein YP_001048886.1 PFAM: isochorismatase hydrolase; KEGG: bch:Bcen2424_4740 isochorismatase hydrolase YP_001048887.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein; KEGG: bxe:Bxe_A0705 transcriptional regulator, AraC family YP_001048888.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shn:Shewana3_0530 transcriptional regulator, LysR family YP_001048889.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shn:Shewana3_0531 lysine exporter protein (LysE/YggA) YP_001048890.1 PFAM: regulatory protein, ArsR; KEGG: son:SO0532 arsenical resistence operon repressor YP_001048891.1 PFAM: permease; KEGG: she:Shewmr4_0534 permease YP_001048892.1 KEGG: son:SO0536 redox-active disulfide protein 2 YP_001048893.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate YP_001048894.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO0539 transporter, putative YP_001048895.1 KEGG: son:SO0540 hypothetical protein YP_001048896.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: sdn:Sden_0649 amino acid carrier protein YP_001048897.1 PFAM: protein of unknown function DUF1704; KEGG: son:SO0542 hypothetical protein YP_001048898.1 KEGG: shn:Shewana3_0540 hypothetical protein YP_001048899.1 KEGG: shm:Shewmr7_3488 hypothetical protein YP_001048900.1 KEGG: shm:Shewmr7_3487 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; CHASE domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001048901.1 PFAM: response regulator receiver; KEGG: shn:Shewana3_0543 response regulator receiver protein YP_001048902.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; KEGG: shn:Shewana3_0544 response regulator receiver modulated diguanylate cyclase/phosphodiesterase YP_001048903.1 TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: shn:Shewana3_0545 alpha-L-glutamate ligases, RimK family YP_001048904.1 KEGG: she:Shewmr4_0547 hypothetical protein YP_001048905.1 PFAM: histone family protein DNA-binding protein; KEGG: she:Shewmr4_0548 histone family protein DNA-binding protein YP_001048906.1 PFAM: response regulator receiver; KEGG: shm:Shewmr7_3481 response regulator receiver protein YP_001048907.1 KEGG: son:SO0550 hypothetical protein YP_001048908.1 KEGG: shm:Shewmr7_3479 hypothetical protein YP_001048909.1 KEGG: son:SO0552 hypothetical protein YP_001048910.1 KEGG: shm:Shewmr7_3477 hypothetical protein YP_001048911.1 KEGG: she:Shewmr4_0554 hypothetical protein YP_001048912.1 PFAM: GGDEF domain containing protein; CBS domain containing protein; EAL domain protein; KEGG: shn:Shewana3_0554 diguanylate cyclase/phosphodiesterase YP_001048913.1 KEGG: shn:Shewana3_0555 conserved hypothetical protein YP_001048914.1 PFAM: GumN family protein; KEGG: shn:Shewana3_0556 GumN family protein YP_001048915.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO0558 smtA protein YP_001048916.1 PFAM: MaoC domain protein dehydratase; KEGG: shn:Shewana3_0558 MaoC domain protein dehydratase YP_001048917.1 PFAM: aldo/keto reductase; KEGG: she:Shewmr4_0560 aldo/keto reductase YP_001048918.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_001048919.1 PFAM: MscS Mechanosensitive ion channel; KEGG: shm:Shewmr7_3468 MscS mechanosensitive ion channel YP_001048920.1 KEGG: son:SO0560.2 hypothetical small-conductance mechanosensitive channel YP_001048921.1 KEGG: son:SO0562 hypothetical protein YP_001048922.1 KEGG: son:SO0563 hypothetical protein YP_001048923.1 KEGG: shm:Shewmr7_3465 hypothetical protein YP_001048924.1 KEGG: shn:Shewana3_0565 conserved hypothetical protein YP_001048925.1 PFAM: periplasmic solute binding protein; KEGG: shn:Shewana3_0566 periplasmic solute binding protein YP_001048926.1 PFAM: ABC-3 protein; KEGG: shn:Shewana3_0567 ABC-3 protein YP_001048927.1 KEGG: shn:Shewana3_0568 1-acyl-sn-glycerol-3-phosphate acyltransferases; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; PFAM: phospholipid/glycerol acyltransferase YP_001048928.1 PFAM: protein of unknown function DUF1260; KEGG: shm:Shewmr7_3460 protein of unknown function DUF1260 YP_001048929.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_3459 diguanylate cyclase YP_001048930.1 PFAM: response regulator receiver; KEGG: shm:Shewmr7_3458 response regulator receiver protein YP_001048931.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001048932.1 KEGG: son:SO0573 hypothetical protein YP_001048933.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_001048934.1 PFAM: PhoH family protein; SMART: AAA ATPase; Nucleotide binding protein, PINc; KEGG: shn:Shewana3_0575 PhoH family protein YP_001048935.1 KEGG: shm:Shewmr7_3453 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Cache domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001048936.1 KEGG: son:SO0578 hypothetical protein YP_001048937.1 PFAM: protein kinase; SMART: serine/threonine protein kinase; KEGG: shm:Shewmr7_3451 serine/threonine protein kinase YP_001048938.1 KEGG: she:Shewmr4_0580 hypothetical protein YP_001048939.1 catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide YP_001048940.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: shn:Shewana3_0581 BFD domain protein (2Fe-2S)-binding domain protein YP_001048941.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; KEGG: she:Shewmr4_0583 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor YP_001048942.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: son:SO0585 D-isomer specific 2-hydroxyacid dehydrogenase family protein YP_001048943.1 KEGG: shn:Shewana3_0584 conserved hypothetical protein YP_001048944.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: son:SO0587 glycerophosphoryl diester phosphodiesterase YP_001048945.1 PFAM: MscS Mechanosensitive ion channel; KEGG: shm:Shewmr7_3443 MscS mechanosensitive ion channel YP_001048946.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: shn:Shewana3_0587 protein of unknown function DUF6, transmembrane YP_001048947.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_001048948.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001048949.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001048950.1 KEGG: shn:Shewana3_0591 conserved hypothetical protein YP_001048951.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family N-terminal domain protein; KEGG: son:SO0598 YjeF protein YP_001048952.1 PFAM: protein of unknown function UPF0079; KEGG: shn:Shewana3_0593 protein of unknown function UPF0079 YP_001048953.1 PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: she:Shewmr4_0595 N-acetylmuramoyl-L-alanine amidase YP_001048954.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001048955.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001048956.1 TIGRFAM: RNA chaperone Hfq; PFAM: Like-Sm ribonucleoprotein, core; KEGG: shn:Shewana3_0597 RNA chaperone Hfq YP_001048957.1 PFAM: GTP-binding protein, HSR1-related; KEGG: son:SO0604 GTP-binding protein HflX YP_001048958.1 TIGRFAM: HflK protein; PFAM: band 7 protein; KEGG: shn:Shewana3_0599 HflK protein YP_001048959.1 TIGRFAM: HflC protein; PFAM: band 7 protein; KEGG: shm:Shewmr7_3429 HflC protein YP_001048960.1 KEGG: shn:Shewana3_0601 ubiquinol-cytochrome c reductase, iron-sulfur subunit; TIGRFAM: ubiquinol-cytochrome c reductase, iron-sulfur subunit; PFAM: Rieske [2Fe-2S] domain protein YP_001048961.1 PFAM: Cytochrome b/b6, N-terminal domain; Cytochrome b/b6, C-terminal domain; KEGG: shm:Shewmr7_3427 cytochrome b/b6, N-terminal domain protein YP_001048962.1 PFAM: cytochrome c1; KEGG: shm:Shewmr7_3426 cytochrome c1 YP_001048963.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_001048964.1 PFAM: Stringent starvation protein B; KEGG: shm:Shewmr7_3424 stringent starvation protein B YP_001048965.1 TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: she:Shewmr4_0607 glutamine amidotransferase of anthranilate synthase YP_001048966.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9B, dipeptidylpeptidase IV domain protein; KEGG: shn:Shewana3_0607 peptidase S9, prolyl oligopeptidase active site domain protein YP_001048967.1 PFAM: HDOD; KEGG: son:SO0615 hypothetical protein YP_001048968.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: shn:Shewana3_0609 alpha/beta hydrolase fold-3 domain protein YP_001048969.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_001048970.1 PFAM: arginine N-succinyltransferase beta subunit; KEGG: shn:Shewana3_0611 arginine N-succinyltransferase beta subunit YP_001048971.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_001048972.1 KEGG: she:Shewmr4_0614 hypothetical protein YP_001048973.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: shn:Shewana3_0614 ATP-binding region, ATPase domain protein domain protein YP_001048974.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO0622 DNA-binding response regulator YP_001048975.1 KEGG: shn:Shewana3_0616 conserved hypothetical protein YP_001048976.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_001048977.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: son:SO0625 hypothetical protein YP_001048978.1 TIGRFAM: 2'-5' RNA ligase; PFAM: 2',5' RNA ligase; KEGG: shm:Shewmr7_3410 2'-5' RNA ligase YP_001048979.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: she:Shewmr4_0621 diguanylate cyclase/phosphodiesterase YP_001048980.1 KEGG: son:SO0632 ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; Helicase ATP-dependent, C-terminal domain protein; SMART: DEAD-like helicases-like YP_001048981.1 KEGG: she:Shewmr4_0624 penicillin-binding protein 1B; TIGRFAM: penicillin-binding protein 1B; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_001048982.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: son:SO0635 peptidyl-prolyl cis-trans isomerase C YP_001048983.1 KEGG: shn:Shewana3_0628 conserved hypothetical protein YP_001048984.1 KEGG: son:SO4012 hypothetical protein YP_001048985.1 KEGG: shn:Shewana3_0631 conserved hypothetical protein YP_001048986.1 KEGG: shn:Shewana3_0632 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001048987.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: shn:Shewana3_0633 molydopterin dinucleotide-binding region YP_001048988.1 PFAM: Polysulphide reductase, NrfD; KEGG: she:Shewmr4_0634 polysulphide reductase, NrfD YP_001048989.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: she:Shewmr4_0635 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001048990.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: shn:Shewana3_0636 ATP-binding region, ATPase domain protein domain protein YP_001048991.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: she:Shewmr4_0637 two component transcriptional regulator, LuxR family YP_001048992.1 KEGG: she:Shewmr4_0638 hypothetical protein YP_001048993.1 KEGG: shn:Shewana3_0639 conserved hypothetical protein YP_001048994.1 KEGG: shm:Shewmr7_3380 hypothetical protein YP_001048995.1 KEGG: son:SO4005 hypothetical protein YP_001048996.1 PFAM: sodium:dicarboxylate symporter; KEGG: shn:Shewana3_0642 sodium:dicarboxylate symporter YP_001048997.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001048998.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001048999.1 KEGG: shn:Shewana3_3517 extracellular solute-binding protein, family 1 YP_001049000.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_0607 binding-protein-dependent transport systems inner membrane component YP_001049001.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: she:Shewmr4_3345 ABC transporter related YP_001049002.1 KEGG: shn:Shewana3_3514 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_001049003.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: shm:Shewmr7_0610 Dyp-type peroxidase family YP_001049004.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shn:Shewana3_3512 transcriptional regulator, LysR family YP_001049005.1 PFAM: NAD-dependent epimerase/dehydratase; NmrA family protein; KEGG: son:SO0768 putative NADH-flavin reductase YP_001049006.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_001049007.1 oxidizes malate to oxaloacetate YP_001049008.1 PFAM: putative thiol-disulphide oxidoreductase DCC; KEGG: son:SO0771 hypothetical protein YP_001049009.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: she:Shewmr4_3337 short-chain dehydrogenase/reductase SDR YP_001049010.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: shn:Shewana3_3506 5-formyltetrahydrofolate cyclo-ligase YP_001049011.1 PFAM: protein of unknown function DUF710; KEGG: shn:Shewana3_3505 fructose-bisphosphatase YP_001049012.1 TIGRFAM: yecA family protein; PFAM: protein of unknown function UPF0149; KEGG: she:Shewmr4_3334 YecA family protein YP_001049013.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; 2-polyprenyl-6-methoxyphenol 4-hydroxylase; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: son:SO0777 2-octaprenyl-6-methoxyphenol hydroxylase YP_001049014.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: son:SO0778 oxidoreductase, FAD-binding, UbiH/Coq6 family YP_001049015.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001049016.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001049017.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001049018.1 PFAM: regulatory protein, TetR; KEGG: msu:MS2295 AcrR protein YP_001049019.1 KEGG: ter:Tery_1993 hypothetical protein YP_001049020.1 KEGG: pfo:Pfl_2244 hypothetical protein YP_001049021.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; KEGG: pst:PSPTO_3079 hypothetical protein YP_001049022.1 KEGG: bam:Bamb_1127 nucleoside-diphosphate-sugar epimerase-like protein YP_001049023.1 KEGG: bja:bll3378 hypothetical protein YP_001049024.1 PFAM: flavin reductase domain protein, FMN-binding; KEGG: bam:Bamb_1242 flavin reductase domain protein, FMN-binding YP_001049025.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: psb:Psyr_2934 NADH:flavin oxidoreductase/NADH oxidase YP_001049026.1 PFAM: tRNA synthetase, class II (G, H, P and S); Anticodon-binding domain protein; KEGG: hch:HCH_02794 threonyl-tRNA synthetase YP_001049028.1 KEGG: pen:PSEEN5201 hypothetical protein YP_001049029.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: xfa:XF1752 transcriptional regulator (LysR family) YP_001049030.1 PFAM: major facilitator superfamily MFS_1; KEGG: pae:PA2219 membrane protein OpdE YP_001049031.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ecj:JW0317 predicted oxidoreductase, Zn-dependent and NAD(P)-binding YP_001049032.1 KEGG: saz:Sama_2710 conserved hypothetical protein YP_001049033.1 KEGG: rso:RSc0206 hypothetical signal peptide protein YP_001049034.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: pha:PSHAa2463 hypothetical protein YP_001049035.1 KEGG: abo:ABO_1660 hypothetical protein YP_001049036.1 KEGG: son:SO0788 hypothetical protein YP_001049037.1 KEGG: son:SO0792 hypothetical protein YP_001049038.1 KEGG: cps:CPS_2516 hypothetical protein YP_001049039.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: she:Shewmr4_3323 methyl-accepting chemotaxis sensory transducer YP_001049040.1 KEGG: son:SO0793 hypothetical protein YP_001049041.1 TIGRFAM: uncharacterized domain; PFAM: OsmC family protein; protein of unknown function DUF181; KEGG: sfr:Sfri_0738 uncharacterized domain YP_001049042.1 KEGG: sde:Sde_0322 hypothetical protein YP_001049043.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shn:Shewana3_3488 diguanylate cyclase YP_001049044.1 PFAM: protein of unknown function DUF985; KEGG: shn:Shewana3_3487 protein of unknown function DUF985 YP_001049045.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001049046.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: shn:Shewana3_3486 alpha/beta hydrolase fold-3 domain protein YP_001049047.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: shm:Shewmr7_0638 MATE efflux family protein YP_001049048.1 PFAM: CBS domain containing protein; KEGG: shn:Shewana3_3483 CBS domain containing membrane protein YP_001049049.1 PFAM: Alkaline phosphatase; KEGG: shn:Shewana3_3482 alkaline phosphatase YP_001049050.1 KEGG: son:SO0807 hypoxanthine-guanine phosphoribosyltransferase YP_001049051.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: she:Shewmr4_3310 glycerophosphoryl diester phosphodiesterase YP_001049052.1 KEGG: she:Shewmr4_3309 hypothetical protein YP_001049053.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001049054.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_3021 integrase, catalytic region YP_001049055.1 KEGG: sdn:Sden_0953 hypothetical protein YP_001049056.1 TIGRFAM: Azurin; PFAM: blue (type 1) copper domain protein; KEGG: shn:Shewana3_3478 blue (type 1) copper domain protein YP_001049057.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_001049058.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific YP_001049059.1 KEGG: shn:Shewana3_3474 conserved hypothetical protein YP_001049060.1 KEGG: shm:Shewmr7_0650 hypothetical protein YP_001049061.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_0651 TonB-dependent siderophore receptor YP_001049062.1 PFAM: HDOD; KEGG: shn:Shewana3_3471 putative signal transduction protein YP_001049063.1 PFAM: transposase, IS4 family protein; KEGG: son:SO3544 ISSod7, transposase YP_001049064.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_0653 transcriptional regulator, LysR family YP_001049065.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001049066.1 KEGG: eca:ECA1971 hypothetical protein YP_001049067.1 TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: shn:Shewana3_0745 putative iron-sulfur cluster binding protein YP_001049068.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shn:Shewana3_0747 diguanylate cyclase YP_001049069.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001049070.1 KEGG: shn:Shewana3_0747 diguanylate cyclase YP_001049071.1 PFAM: phosphoesterase, PA-phosphatase related; KEGG: she:Shewmr4_3190 phosphoesterase, PA-phosphatase related YP_001049072.1 KEGG: son:SO3856 hypothetical protein YP_001049073.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_001049074.1 PFAM: protein of unknown function DUF1456; KEGG: shm:Shewmr7_0779 protein of unknown function DUF1456 YP_001049075.1 KEGG: she:Shewmr4_3186 putative manganese transporter YP_001049076.1 PFAM: membrane-flanked domain; KEGG: son:SO3849 hypothetical protein YP_001049077.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shn:Shewana3_0754 TonB-dependent receptor YP_001049078.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: shm:Shewmr7_0783 glutathione S-transferase, N-terminal domain protein YP_001049079.1 KEGG: shm:Shewmr7_0784 hypothetical protein YP_001049080.1 KEGG: shn:Shewana3_0757 conserved hypothetical protein YP_001049081.1 KEGG: shm:Shewmr7_0786 hypothetical protein YP_001049082.1 PFAM: peptidase M13, neprilysin; peptidase M13; KEGG: she:Shewmr4_3179 endothelin-converting enzyme 1 YP_001049083.1 KEGG: aha:AHA_3355 nodulation protein L YP_001049084.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: she:Shewmr4_3178 pseudouridine synthase, Rsu YP_001049085.1 KEGG: shm:Shewmr7_0789 hypothetical protein YP_001049086.1 KEGG: shn:Shewana3_0762 conserved hypothetical protein YP_001049087.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: she:Shewmr4_3175 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001049088.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shn:Shewana3_0764 methyl-accepting chemotaxis sensory transducer YP_001049089.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001049090.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001049091.1 PFAM: outer membrane lipoprotein LolB; KEGG: son:SO3835 outer membrane lipoprotein LolB YP_001049092.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001049093.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001049094.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: she:Shewmr4_3168 modification methylase, HemK family YP_001049095.1 KEGG: saz:Sama_2552 OmpA-like transmembrane domain protein YP_001049096.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_0771 pantoate--beta-alanine ligase YP_001049097.1 PFAM: Invasion gene expression up-regulator, SirB; KEGG: shn:Shewana3_0772 invasion gene expression up-regulator, SirB YP_001049098.1 KEGG: shm:Shewmr7_0801 hypothetical protein YP_001049099.1 PFAM: protein of unknown function DUF819; KEGG: shn:Shewana3_0774 protein of unknown function DUF819 YP_001049100.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001049101.1 KEGG: son:SO3822 hypothetical protein YP_001049102.1 PFAM: EAL domain protein; KEGG: shn:Shewana3_0777 EAL domain protein YP_001049103.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: shm:Shewmr7_0807 ammonium transporter YP_001049104.1 PFAM: nitrogen regulatory protein P-II; KEGG: son:SO3819 nitrogen regulatory protein P-II YP_001049105.1 KEGG: she:Shewmr4_3158 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein YP_001049106.1 PFAM: VanZ family protein; KEGG: shn:Shewana3_0781 VanZ family protein YP_001049107.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001049108.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO3814 AmpG protein, putative YP_001049109.1 KEGG: she:Shewmr4_3154 hypothetical protein YP_001049110.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: shn:Shewana3_0785 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001049111.1 PFAM: Uncharacterized lipoprotein; KEGG: shm:Shewmr7_0815 uncharacterized lipoprotein YP_001049112.1 KEGG: son:SO3810 OmpA-like transmembrane domain protein YP_001049113.1 KEGG: she:Shewmr4_3150 hypothetical protein YP_001049114.1 KEGG: shm:Shewmr7_0818 sterol desaturase family protein YP_001049115.1 KEGG: shm:Shewmr7_0819 hypothetical protein YP_001049116.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: shm:Shewmr7_0820 UDP-N-acetylmuramate YP_001049117.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; KEGG: shn:Shewana3_0792 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001049118.1 KEGG: shn:Shewana3_0793 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_001049119.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO3802 ABC transporter, ATP-binding protein YP_001049120.1 PFAM: ABC-2 type transporter; KEGG: son:SO3801 ABC transporter, permease protein YP_001049121.1 PFAM: transposase, IS4 family protein; KEGG: son:SO3544 ISSod7, transposase YP_001049122.1 PFAM: Integrase, catalytic region; KEGG: sfr:Sfri_4013 integrase, catalytic region YP_001049123.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfr:Sfri_4014 transposase IS3/IS911 family protein YP_001049124.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; PKD domain containing protein; protease-associated PA domain protein; KEGG: shn:Shewana3_1690 protease-associated PA domain protein YP_001049125.1 KEGG: aeh:Mlg_2336 hypothetical protein YP_001049126.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001049127.1 KEGG: shm:Shewmr7_0825 protease-associated PA domain protein YP_001049128.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_001049129.1 PFAM: pseudouridine synthase; KEGG: she:Shewmr4_3139 pseudouridylate synthase YP_001049130.1 PFAM: peptidase U32; KEGG: shm:Shewmr7_0828 peptidase U32 YP_001049131.1 PFAM: protein of unknown function DUF1696; KEGG: shm:Shewmr7_0829 protein of unknown function DUF1696 YP_001049132.1 PFAM: Abortive infection protein; KEGG: shn:Shewana3_0802 abortive infection protein YP_001049133.1 KEGG: son:SO3794 hypothetical protein YP_001049134.1 KEGG: son:SO3793 hypothetical protein YP_001049135.1 KEGG: shn:Shewana3_0804 cupin 2, conserved barrel domain protein YP_001049136.1 KEGG: she:Shewmr4_3134 hypothetical protein YP_001049137.1 PFAM: peptidase M19, renal dipeptidase; KEGG: shn:Shewana3_0806 peptidase M19, renal dipeptidase YP_001049138.1 PFAM: Fe-S metabolism associated SufE; KEGG: she:Shewmr4_3132 Fe-S metabolism associated SufE YP_001049139.1 TIGRFAM: cysteine desulfurases, SufS subfamily; PFAM: aminotransferase, class V; aminotransferase, class I and II; KEGG: son:SO3789 aminotransferase, class V YP_001049140.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shn:Shewana3_3383 TonB-dependent receptor, plug YP_001049141.1 KEGG: shn:Shewana3_3382 hypothetical protein YP_001049142.1 PFAM: MltA-interacting MipA family protein; KEGG: sfr:Sfri_3064 MltA-interacting MipA family protein YP_001049143.1 KEGG: sfr:Sfri_3063 hypothetical protein YP_001049144.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sdn:Sden_0557 response regulator receiver YP_001049145.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: sfr:Sfri_3061 periplasmic sensor signal transduction histidine kinase YP_001049146.1 KEGG: sfr:Sfri_3059 hypothetical protein YP_001049147.1 PFAM: MltA-interacting MipA family protein; KEGG: sfr:Sfri_3058 MltA-interacting MipA family protein YP_001049148.1 PFAM: aldo/keto reductase; KEGG: shm:Shewmr7_3273 aldo/keto reductase YP_001049149.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001049150.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001049151.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001049152.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_001049153.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_001049154.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001049155.1 PFAM: Amidohydrolase 3; KEGG: mac:MA0761 exoenzymes regulatory protein precursor YP_001049156.1 KEGG: son:SO0915 ankyrin domain protein YP_001049157.1 PFAM: GCN5-related N-acetyltransferase; regulatory protein, MarR; KEGG: shn:Shewana3_3368 transcriptional regulator, MarR family with acetyltransferase activity YP_001049158.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_001049159.1 PFAM: peptidase S45, penicillin amidase; KEGG: shm:Shewmr7_3263 peptidase S45, penicillin amidase YP_001049160.1 PFAM: aromatic amino acid permease; KEGG: shm:Shewmr7_3262 amino acid transporter, transmembrane YP_001049161.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO0920 acetyltransferase, GNAT family YP_001049162.1 KEGG: son:SO0921 hypothetical protein YP_001049163.1 PFAM: sodium:dicarboxylate symporter; KEGG: shn:Shewana3_3362 sodium:dicarboxylate symporter YP_001049164.1 PFAM: protein of unknown function DUF306, Meta and HslJ; KEGG: shm:Shewmr7_3258 protein of unknown function DUF306, MetA and HslJ YP_001049165.1 KEGG: shm:Shewmr7_3257 hypothetical protein YP_001049166.1 KEGG: shm:Shewmr7_3256 GGDEF domain protein YP_001049167.1 KEGG: shn:Shewana3_3358 acetyltransferase, GNAT family YP_001049168.1 KEGG: shm:Shewmr7_3253 hypothetical protein YP_001049169.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdn:Sden_1378 GCN5-related N-acetyltransferase YP_001049170.1 KEGG: sfr:Sfri_1956 type I site-specific deoxyribonuclease, HsdR family protein; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like YP_001049172.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001049173.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001049174.1 PFAM: Uncharacterized protein UPF0114; KEGG: sdn:Sden_0436 uncharacterized protein UPF0114 YP_001049175.1 KEGG: son:SO3996 hypothetical protein YP_001049177.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001049178.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001049179.1 PFAM: peptidase S15; peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9B, dipeptidylpeptidase IV domain protein; KEGG: shn:Shewana3_0649 peptidase S9B, dipeptidylpeptidase IV domain protein YP_001049180.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shn:Shewana3_0650 two component transcriptional regulator, winged helix family YP_001049181.1 KEGG: shn:Shewana3_0651 conserved hypothetical protein YP_001049182.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_001049183.1 PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: son:SO3985 hypothetical protein YP_001049184.1 PFAM: Mg2+ transporter protein, CorA family protein; KEGG: shn:Shewana3_0654 Mg2 transporter protein, CorA family protein YP_001049185.1 PFAM: Uncharacterised conserved protein UCP006287; KEGG: son:SO3983 hypothetical protein YP_001049186.1 PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: shn:Shewana3_0656 two component transcriptional regulator, LuxR family YP_001049187.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase, dimerisation and phosphoacceptor region; KEGG: shn:Shewana3_0657 signal transduction histidine kinase, nitrate/nitrite-specific, NarQ YP_001049188.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_001049189.1 KEGG: sfr:Sfri_3123 hypothetical protein YP_001049190.1 PFAM: isochorismatase hydrolase; KEGG: she:Shewmr4_3363 isochorismatase hydrolase YP_001049191.1 PFAM: nitrogen regulatory protein P-II; KEGG: son:SO0761 nitrogen regulatory protein P-II 1 YP_001049192.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: shn:Shewana3_3531 Rh family protein/ammonium transporter YP_001049193.1 KEGG: she:Shewmr4_3360 hypothetical protein YP_001049194.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: she:Shewmr4_3359 tetratricopeptide TPR_2 repeat protein YP_001049195.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001049196.1 KEGG: shn:Shewana3_3527 conserved hypothetical protein YP_001049197.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: she:Shewmr4_3356 ABC transporter related YP_001049198.1 KEGG: shm:Shewmr7_0598 hypothetical protein YP_001049199.1 KEGG: son:SO0752 hypothetical protein YP_001049200.1 PFAM: ferredoxin-dependent glutamate synthase; KEGG: shm:Shewmr7_0600 ferredoxin-dependent glutamate synthase YP_001049201.1 PFAM: Phosphoglycerate mutase; KEGG: son:SO0749 hypothetical protein YP_001049202.1 KEGG: son:SO0748 hypothetical protein YP_001049203.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: she:Shewmr4_3350 oxidoreductase FAD/NAD(P)-binding domain protein YP_001049204.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: shn:Shewana3_3519 glutathione S-transferase, N-terminal domain protein YP_001049205.1 KEGG: shm:Shewmr7_0605 hypothetical protein YP_001049206.1 KEGG: shn:Shewana3_3517 extracellular solute-binding protein, family 1 YP_001049207.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001049208.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001049210.1 PFAM: restriction modification system DNA specificity domain; KEGG: sfr:Sfri_1954 restriction modification system DNA specificity domain YP_001049211.1 KEGG: aeh:Mlg_2336 hypothetical protein YP_001049212.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001049213.1 KEGG: lil:LA3198 type I restriction enzyme EcoprrI specificity protein YP_001049214.1 PFAM: protein of unknown function DUF1016; KEGG: neu:NE2308 hypothetical protein YP_001049215.1 TIGRFAM: type I restriction-modification system, M subunit; PFAM: putative RNA methylase; N-6 DNA methylase; KEGG: sfr:Sfri_1953 type I restriction-modification system, M subunit YP_001049216.1 KEGG: sfr:Sfri_1952 hypothetical protein YP_001049217.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF955; KEGG: sfr:Sfri_1951 helix-turn-helix domain protein YP_001049218.1 PFAM: phage integrase family protein; KEGG: sfr:Sfri_1950 phage integrase family protein YP_001049219.1 KEGG: shn:Shewana3_2432 hypothetical protein YP_001049220.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001049221.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001049222.2 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_001049223.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001049224.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_001049225.1 PFAM: protein of unknown function DUF481; KEGG: shn:Shewana3_3349 protein of unknown function DUF481 YP_001049226.1 PFAM: Citrate transporter; KEGG: shn:Shewana3_3348 Na+/H+ antiporter YP_001049227.1 PFAM: transcriptional regulator domain protein; KEGG: shm:Shewmr7_3240 transcriptional regulator, CadC YP_001049228.1 KEGG: she:Shewmr4_0784 hypothetical protein YP_001049229.1 KEGG: son:SO0942 hypothetical protein YP_001049230.1 KEGG: she:Shewmr4_0786 putative PAS/PAC sensor protein YP_001049231.1 PFAM: Radical SAM domain protein; KEGG: shm:Shewmr7_3236 radical SAM domain protein YP_001049232.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_3235 acriflavin resistance protein YP_001049233.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shn:Shewana3_3337 efflux transporter, RND family, MFP subunit YP_001049234.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_001049235.1 KEGG: shn:Shewana3_3333 methyltransferase small YP_001049236.1 PFAM: branched-chain amino acid transport system II carrier protein; KEGG: shn:Shewana3_3332 branched-chain amino acid transport system II carrier protein YP_001049237.1 TIGRFAM: tyrosine recombinase XerD; PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: shn:Shewana3_3331 tyrosine recombinase XerD YP_001049238.1 KEGG: shm:Shewmr7_3227 thiol:disulfide interchange protein DsbC YP_001049239.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: shm:Shewmr7_3226 single-stranded-DNA-specific exonuclease RecJ YP_001049240.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_0799 GCN5-related N-acetyltransferase YP_001049241.1 KEGG: sdn:Sden_1933 hypothetical protein YP_001049242.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO0956 alkyl hydroperoxide reductase, F subunit YP_001049243.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: son:SO0958 alkyl hydroperoxide reductase, C subunit YP_001049244.1 PFAM: peptidase M17, leucyl aminopeptidase domain protein; KEGG: shm:Shewmr7_3221 leucyl aminopeptidase YP_001049245.1 KEGG: shm:Shewmr7_3220 spermine synthase YP_001049246.1 KEGG: shn:Shewana3_3322 conserved hypothetical protein YP_001049247.1 PFAM: PepSY-associated TM helix domain protein; KEGG: sfr:Sfri_0270 hypothetical protein YP_001049248.1 KEGG: sdn:Sden_0345 PepSY-associated TM helix YP_001049249.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: ilo:IL1228 outer membrane protein YP_001049250.1 KEGG: sdn:Sden_3531 hypothetical protein YP_001049251.1 PFAM: dienelactone hydrolase; KEGG: she:Shewmr4_0806 dienelactone hydrolase YP_001049252.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: shn:Shewana3_3319 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001049253.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: shn:Shewana3_3318 flavocytochrome c YP_001049254.1 KEGG: she:Shewmr4_0809 hypothetical protein YP_001049255.1 PFAM: Tellurite resistance protein TehB; Methyltransferase type 12; KEGG: shm:Shewmr7_3213 methyltransferase type 12 YP_001049256.1 KEGG: shn:Shewana3_3315 conserved hypothetical protein YP_001049257.1 KEGG: shn:Shewana3_3314 conserved hypothetical protein YP_001049258.1 KEGG: shm:Shewmr7_3210 hypothetical protein YP_001049259.1 PFAM: OsmC family protein; KEGG: shm:Shewmr7_3209 OsmC family protein YP_001049260.1 PFAM: regulatory protein, MarR; KEGG: shn:Shewana3_3311 transcriptional regulator, MarR family YP_001049261.1 PFAM: FAD dependent oxidoreductase; KEGG: shn:Shewana3_3310 FAD dependent oxidoreductase YP_001049262.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_001049263.1 TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter; KEGG: shn:Shewana3_3300 chromate transporter, chromate ion transporter (CHR) family YP_001049264.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: shn:Shewana3_3299 methyl-accepting chemotaxis sensory transducer YP_001049265.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: shm:Shewmr7_3198 formate dehydrogenase, alpha subunit YP_001049266.1 TIGRFAM: peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein; KEGG: shm:Shewmr7_3197 peptide chain release factor 2 YP_001049267.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001049268.1 PFAM: carbon starvation protein CstA; KEGG: shn:Shewana3_0888 carbon starvation protein CstA YP_001049269.1 KEGG: hch:HCH_03207 catalase/peroxidase HPI; TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase YP_001049270.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: sfr:Sfri_1868 uncharacterized domain 1 YP_001049271.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_001049272.1 PFAM: phosphate transporter; KEGG: shn:Shewana3_0892 phosphate transporter YP_001049273.1 KEGG: son:SO1053 hypothetical protein YP_001049274.1 PFAM: protein of unknown function DUF72; KEGG: shn:Shewana3_0893 protein of unknown function DUF72 YP_001049275.1 KEGG: shn:Shewana3_0894 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001049276.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_3042 methyl-accepting chemotaxis sensory transducer YP_001049277.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: shm:Shewmr7_0932 aminopeptidase N YP_001049278.1 TIGRFAM: membrane lipoprotein lipid attachment site; KEGG: shn:Shewana3_0898 conserved hypothetical protein YP_001049279.1 PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: son:SO1061 TPR domain protein YP_001049280.1 KEGG: shm:Shewmr7_0937 peptide deformylase; TIGRFAM: peptide deformylase; PFAM: formylmethionine deformylase YP_001049281.1 PFAM: SlyX family protein; KEGG: son:SO1063 SlyX protein YP_001049282.1 PFAM: WD-40 repeat protein; KEGG: shn:Shewana3_0902 WD-40 repeat protein YP_001049283.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type; KEGG: she:Shewmr4_3034 peptidylprolyl isomerase, FKBP-type YP_001049284.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: she:Shewmr4_3033 endonuclease/exonuclease/phosphatase YP_001049285.1 KEGG: she:Shewmr4_3032 hypothetical protein YP_001049286.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_0943 uncharacterized domain 1 YP_001049287.1 KEGG: saz:Sama_2943 conserved hypothetical protein YP_001049288.1 PFAM: Catalase domain protein; KEGG: she:Shewmr4_3029 catalase YP_001049289.1 PFAM: protein of unknown function UPF0016; KEGG: shn:Shewana3_0909 protein of unknown function UPF0016 YP_001049290.1 GbpA; plays a role mediating bacterial attachment and colonization of zooplankton and/or intestinal epithelium; in Vibrio cholerae this protein probably binds directly N-acetylglucosamine residues in chitin, glycoproteins and lipids on intestinal epithelial cells YP_001049291.1 PFAM: aromatic amino acid permease; Amino acid transporter, transmembrane; KEGG: shn:Shewana3_0912 aromatic amino acid permease YP_001049292.1 KEGG: shn:Shewana3_0913 conserved hypothetical protein YP_001049293.1 KEGG: shn:Shewana3_4378 hypothetical protein YP_001049294.1 PFAM: transposase, IS4 family protein; KEGG: shm:Shewmr7_3098 transposase, IS4 family protein YP_001049295.1 PFAM: OmpA/MotB domain protein; KEGG: shn:Shewana3_0915 OmpA/MotB domain protein YP_001049296.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: shm:Shewmr7_0952 pseudouridine synthase, Rsu YP_001049297.1 PFAM: Na+/H+ antiporter NhaC; KEGG: shn:Shewana3_0918 Na+/H+ antiporter NhaC YP_001049298.1 KEGG: shn:Shewana3_0919 conserved hypothetical protein YP_001049299.1 PFAM: FMN-binding domain protein; KEGG: shn:Shewana3_0920 FMN-binding domain protein YP_001049300.1 KEGG: shm:Shewmr7_0957 ApbE family protein, putative YP_001049301.1 KEGG: shn:Shewana3_0922 conserved hypothetical protein YP_001049302.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shn:Shewana3_0923 methyl-accepting chemotaxis sensory transducer YP_001049303.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: shn:Shewana3_0924 protein of unknown function DUF6, transmembrane YP_001049304.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: shn:Shewana3_0925 transcriptional regulator, AraC family YP_001049305.1 KEGG: shn:Shewana3_0926 GreA/GreB family elongation factor YP_001049306.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001049307.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II; KEGG: shn:Shewana3_0927 cytochrome d ubiquinol oxidase, subunit II YP_001049308.1 PFAM: cytochrome bd ubiquinol oxidase, subunit I; KEGG: shn:Shewana3_0928 cytochrome bd ubiquinol oxidase, subunit I YP_001049309.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: shm:Shewmr7_0965 transcriptional regulator, GntR family YP_001049310.1 KEGG: shm:Shewmr7_0966 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_001049311.1 KEGG: son:SO1096 hypothetical protein YP_001049312.1 PFAM: methyltransferase small; KEGG: shn:Shewana3_0932 methyltransferase small YP_001049313.1 KEGG: shm:Shewmr7_0969 2OG-Fe(II) oxygenase YP_001049314.1 PFAM: BolA family protein; KEGG: shm:Shewmr7_0970 BolA family protein YP_001049315.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: she:Shewmr4_0933 TRAP dicarboxylate transporter-DctP subunit YP_001049316.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_001049317.1 PFAM: TonB-dependent receptor; KEGG: she:Shewmr4_0935 TonB-dependent receptor YP_001049318.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001049319.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001049320.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001049321.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_001049322.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_001049323.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001049324.1 PFAM: ApbE family lipoprotein; KEGG: shm:Shewmr7_0980 ApbE family lipoprotein YP_001049325.1 PFAM: protein of unknown function DUF539; KEGG: shn:Shewana3_0945 protein of unknown function DUF539 YP_001049326.1 TIGRFAM: bacterioferritin; PFAM: Ferritin, Dps family protein; KEGG: shn:Shewana3_0946 bacterioferritin YP_001049327.1 TIGRFAM: bacterioferritin; PFAM: Ferritin, Dps family protein; KEGG: son:SO1112 bacterioferritin subunit 1 YP_001049328.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shn:Shewana3_0948 methyl-accepting chemotaxis sensory transducer YP_001049329.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001049330.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: shn:Shewana3_2723 protein of unknown function DUF6, transmembrane YP_001049331.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: ilo:IL2343 methyl-accepting chemotaxis protein (contains HAMP domain) YP_001049332.1 KEGG: vch:VCA0032 hypothetical protein YP_001049333.1 KEGG: shn:Shewana3_0950 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001049334.1 PFAM: peptidase M17, leucyl aminopeptidase domain protein; KEGG: shn:Shewana3_0951 dihydrofolate reductase YP_001049335.1 KEGG: sfr:Sfri_0964 hypothetical protein YP_001049337.1 KEGG: shn:Shewana3_3243 conserved hypothetical protein YP_001049338.1 KEGG: son:SO3676 hypothetical protein YP_001049339.1 with HmuTU is involved in the transport of hemin YP_001049340.1 PFAM: transport system permease protein; ABC-3 protein; KEGG: shn:Shewana3_3240 transport system permease protein YP_001049341.1 PFAM: periplasmic binding protein; KEGG: shn:Shewana3_3239 periplasmic binding protein YP_001049342.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: shn:Shewana3_3238 biopolymer transport protein ExbD/TolR YP_001049343.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: shn:Shewana3_3237 MotA/TolQ/ExbB proton channel YP_001049344.1 TIGRFAM: TonB family protein; KEGG: shn:Shewana3_3236 TonB family protein YP_001049345.1 TIGRFAM: TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shn:Shewana3_3235 TonB-dependent heme/hemoglobin receptor family protein YP_001049346.1 PFAM: protein of unknown function DUF1008; KEGG: son:SO3668 hypothetical protein YP_001049347.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding; KEGG: son:SO3667 hypothetical protein YP_001049348.1 KEGG: shm:Shewmr7_3140 lipid A ABC exporter family, fused ATPase and inner membrane subunits; TIGRFAM: lipid A ABC exporter family, fused ATPase and inner membrane subunits; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001049349.1 PFAM: AMP-dependent synthetase and ligase; KEGG: shn:Shewana3_3231 AMP-dependent synthetase and ligase YP_001049350.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shn:Shewana3_3228 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001049351.1 KEGG: she:Shewmr4_0887 transcriptional regulator, fis family; TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; AAA ATPase YP_001049352.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_3096 TonB-dependent receptor YP_001049353.1 KEGG: she:Shewmr4_0888 thiol:disulfide interchange protein, putative YP_001049354.1 PFAM: peptidase S10, serine carboxypeptidase; KEGG: shn:Shewana3_3225 peptidase S10, serine carboxypeptidase YP_001049355.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shn:Shewana3_3224 lysine exporter protein (LysE/YggA) YP_001049356.1 KEGG: son:SO3656 hypothetical protein YP_001049357.1 KEGG: son:SO3655 pilin, putative YP_001049358.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001049359.1 PFAM: Polyprenyl synthetase; KEGG: she:Shewmr4_0894 trans-hexaprenyltranstransferase YP_001049360.1 PFAM: ribosomal protein L21; KEGG: sfr:Sfri_3089 ribosomal protein L21 YP_001049361.1 involved in the peptidyltransferase reaction during translation YP_001049362.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001049363.1 PFAM: protein of unknown function DUF1212; KEGG: she:Shewmr4_0898 protein of unknown function DUF1212 YP_001049364.1 KEGG: son:SO3647 hypothetical protein YP_001049365.1 PFAM: dihydrofolate reductase region; KEGG: shm:Shewmr7_3120 dihydrofolate reductase YP_001049366.1 KEGG: shm:Shewmr7_3119 hypothetical protein YP_001049367.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shn:Shewana3_3212 methyl-accepting chemotaxis sensory transducer YP_001049368.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_001049369.1 protein associated with Co2+ and Mg2+ efflux YP_001049370.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001049371.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001049372.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: shn:Shewana3_3207 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001049373.1 PFAM: OstA family protein; Organic solvent tolerance protein; KEGG: shn:Shewana3_3206 organic solvent tolerance protein YP_001049374.1 PFAM: aminoglycoside phosphotransferase; KEGG: shn:Shewana3_3205 aminoglycoside phosphotransferase YP_001049375.1 PFAM: Nucleotidyl transferase; KEGG: son:SO3634 nucleotidyltransferase family protein YP_001049376.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_001049377.1 KEGG: shn:Shewana3_3202 conserved hypothetical protein YP_001049378.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: shn:Shewana3_3201 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001049379.1 SMART: Tetratricopeptide domain protein; KEGG: shn:Shewana3_3199 tetratricopeptide domain protein YP_001049380.1 KEGG: she:Shewmr4_3021 hypothetical protein YP_001049381.1 PFAM: pseudouridine synthase; KEGG: sdn:Sden_0688 pseudouridine synthase YP_001049382.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001049383.1 KEGG: shn:Shewana3_3194 conserved hypothetical protein YP_001049384.1 PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_3096 secretion protein HlyD family protein YP_001049385.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: she:Shewmr4_3019 AAA ATPase, central domain protein YP_001049386.1 KEGG: son:SO3597 hypothetical protein YP_001049387.1 KEGG: son:SO3602 sulfate ABC transporter, ATP-binding protein; TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001049388.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysW; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shn:Shewana3_3191 sulfate ABC transporter, inner membrane subunit CysW YP_001049389.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO3600 sulfate ABC transporter, permease protein YP_001049390.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein, family 1; KEGG: she:Shewmr4_3012 sulfate ABC transporter, periplasmic sulfate-binding protein YP_001049391.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_001049392.1 KEGG: shn:Shewana3_3187 conserved hypothetical protein YP_001049393.1 PFAM: protein of unknown function DUF1289; KEGG: shn:Shewana3_3186 protein of unknown function DUF1289 YP_001049394.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: shn:Shewana3_3185 ATP-binding region, ATPase domain protein domain protein YP_001049395.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shn:Shewana3_3184 two component transcriptional regulator, winged helix family YP_001049396.1 KEGG: shn:Shewana3_3183 conserved hypothetical protein YP_001049397.1 PFAM: MltA-interacting MipA family protein; KEGG: shn:Shewana3_3182 MltA-interacting MipA family protein YP_001049398.1 KEGG: shn:Shewana3_3181 conserved hypothetical protein YP_001049399.1 PFAM: GPR1/FUN34/yaaH family protein; KEGG: son:SO3588 gpr1/fun34/YaaH family protein YP_001049400.1 KEGG: son:SO3587 hypothetical protein YP_001049401.1 KEGG: aha:AHA_0121 tellurite resistance protein TehB YP_001049402.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: shn:Shewana3_3178 glyoxalase/bleomycin resistance protein/dioxygenase YP_001049403.1 PFAM: NADPH-dependent FMN reductase; KEGG: shn:Shewana3_3177 NADPH-dependent FMN reductase YP_001049404.1 PFAM: Helix-turn-helix, type 11 domain protein; KEGG: she:Shewmr4_2998 putative transcriptional regulator YP_001049405.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: ppr:PBPRA2309 hypothetical protein YP_001049406.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: she:Shewmr4_2997 pseudouridine synthase, Rsu YP_001049407.1 PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: shn:Shewana3_3174 globin YP_001049408.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shn:Shewana3_3173 methyl-accepting chemotaxis sensory transducer YP_001049409.1 KEGG: shm:Shewmr7_3075 putative lipoprotein YP_001049410.1 KEGG: shn:Shewana3_3171 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001049411.1 PFAM: protein of unknown function DUF152; KEGG: son:SO3578 conserved hypothetical protein TIGR00726 YP_001049412.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: son:SO3577 clpB protein YP_001049413.1 KEGG: shn:Shewana3_3168 conserved hypothetical protein YP_001049414.1 KEGG: son:SO3575 CDP-diacylglycerol--serine O-phosphatidyltransferase, putative; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001049415.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001049416.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001049417.1 TIGRFAM: sodium pump decarboxylases, gamma subunit; PFAM: sodium pump decarboxylase, gamma subunit; KEGG: shn:Shewana3_3166 sodium pump decarboxylases, gamma subunit YP_001049418.1 catalyzes the formation of pyruvate from oxaloacetate YP_001049419.1 KEGG: shm:Shewmr7_3067 sodium ion-translocating decarboxylase, beta subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit YP_001049420.1 KEGG: shm:Shewmr7_3066 hypothetical protein YP_001049421.1 PFAM: sodium:dicarboxylate symporter; KEGG: shn:Shewana3_3163 sodium:dicarboxylate symporter YP_001049422.1 KEGG: she:Shewmr4_2982 hypothetical protein YP_001049423.1 PFAM: peptidase M16 domain protein; KEGG: shn:Shewana3_3161 peptidase M16 domain protein YP_001049424.1 involved in the first step of glutathione biosynthesis YP_001049425.1 KEGG: shn:Shewana3_3159 conserved hypothetical protein YP_001049426.1 KEGG: shm:Shewmr7_3060 hypothetical protein YP_001049427.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: shm:Shewmr7_3059 diguanylate cyclase with GAF sensor YP_001049428.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001049429.1 KEGG: son:SO3554 phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_001049430.1 putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_001049431.1 PFAM: von Willebrand factor, type A; KEGG: shn:Shewana3_3153 von Willebrand factor, type A YP_001049432.1 PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2; KEGG: shn:Shewana3_3152 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001049433.1 KEGG: shn:Shewana3_3151 conserved hypothetical protein YP_001049434.1 PFAM: Hemerythrin HHE cation binding domain protein; KEGG: shn:Shewana3_3150 hemerythrin HHE cation binding domain protein YP_001049435.1 KEGG: shn:Shewana3_3149 conserved hypothetical protein YP_001049436.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001049437.1 KEGG: she:Shewmr4_2967 transaldolase; TIGRFAM: transaldolase; PFAM: Transaldolase YP_001049438.1 PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: son:SO3545 OmpA family protein YP_001049439.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: son:SO3542 putative phosphoketolase YP_001049440.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: shn:Shewana3_3144 amino acid carrier protein YP_001049441.1 PFAM: protein of unknown function DUF328; KEGG: shm:Shewmr7_3045 protein of unknown function DUF328 YP_001049442.1 PFAM: peptidase M20; peptidase M28; KEGG: she:Shewmr4_2962 peptidase M28 YP_001049443.1 PFAM: regulatory protein, ArsR; KEGG: shn:Shewana3_3141 transcriptional regulator, ArsR family YP_001049444.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001049445.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: she:Shewmr4_2959 integral membrane protein MviN YP_001049446.1 KEGG: shn:Shewana3_3137 riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase YP_001049447.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001049448.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001049449.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: shn:Shewana3_3134 peptidylprolyl isomerase, FKBP-type YP_001049450.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001049451.1 TIGRFAM: type IV pilus modification protein PilV; KEGG: son:SO3528 type IV pilus assembly protein PilV YP_001049452.1 KEGG: son:SO3527 type IV pilus assembly protein PilW YP_001049453.1 KEGG: son:SO3526 type IV pilus assembly protein PilX YP_001049454.1 KEGG: shn:Shewana3_3129 type IV pilin biogenesis protein, putative YP_001049455.1 KEGG: son:SO3524 type IV pilus biogenesis protein PilE YP_001049456.1 KEGG: son:SO3523 hypothetical protein YP_001049457.1 KEGG: son:SO3521 type IV pilus biogenesis protein, putative YP_001049458.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001049459.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001049460.1 KEGG: son:SO3520 type IV pilus biogenesis protein, putative YP_001049461.1 PFAM: nitrogen regulatory protein P-II; KEGG: saz:Sama_0935 nitrogen regulatory protein P-II YP_001049462.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: shm:Shewmr7_3026 NADH dehydrogenase YP_001049463.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: shm:Shewmr7_3025 transcriptional regulator, LacI family YP_001049464.1 PFAM: TonB-dependent receptor, plug; KEGG: she:Shewmr4_2942 TonB-dependent receptor YP_001049465.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_3021 integrase, catalytic region YP_001049466.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001049467.1 PFAM: TonB-dependent receptor; KEGG: son:SO3514 hypothetical TonB-dependent receptor YP_001049468.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001049469.1 PFAM: SapC family protein; KEGG: sfr:Sfri_2877 SapC family protein YP_001049470.1 PFAM: tryptophan halogenase; KEGG: cps:CPS_1023 putative tryptophan halogenase YP_001049471.1 PFAM: FAD dependent oxidoreductase; tryptophan halogenase; KEGG: shm:Shewmr7_3023 tryptophan halogenase YP_001049472.1 PFAM: protein of unknown function DUF81; KEGG: shm:Shewmr7_3021 protein of unknown function DUF81 YP_001049473.1 KEGG: shn:Shewana3_3117 hypothetical protein YP_001049474.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shn:Shewana3_3116 methyl-accepting chemotaxis sensory transducer YP_001049475.1 PFAM: ATPase, BadF/BadG/BcrA/BcrD type; KEGG: shn:Shewana3_3114 ATPase, BadF/BadG/BcrA/BcrD type YP_001049476.1 PFAM: sugar isomerase (SIS); KEGG: shn:Shewana3_3113 sugar isomerase (SIS) YP_001049477.1 KEGG: she:Shewmr4_2933 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase YP_001049478.1 KEGG: she:Shewmr4_2932 hypothetical protein YP_001049479.1 TIGRFAM: glucose/galactose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: son:SO3503 glucose/galactose transporter YP_001049480.1 KEGG: shn:Shewana3_3109 conserved hypothetical protein YP_001049481.1 PFAM: protein of unknown function DUF861, cupin_3; KEGG: shm:Shewmr7_3011 protein of unknown function DUF861, cupin_3 YP_001049482.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: shn:Shewana3_3107 methylmalonate-semialdehyde dehydrogenase YP_001049483.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_001049484.1 PFAM: aldehyde dehydrogenase; KEGG: she:Shewmr4_2926 aldehyde dehydrogenase (NAD(+)) YP_001049485.1 PFAM: transposase, IS4 family protein; KEGG: shm:Shewmr7_3098 transposase, IS4 family protein YP_001049486.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001049487.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001049489.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; KEGG: shn:Shewana3_3104 rare lipoprotein A YP_001049490.1 PFAM: Rhodanese domain protein; KEGG: shm:Shewmr7_3006 3-mercaptopyruvate sulfurtransferase YP_001049491.1 PFAM: Rhodanese domain protein; KEGG: son:SO1261 mercaptopyruvate sulfurtransferase YP_001049492.1 KEGG: shn:Shewana3_3102 conserved hypothetical protein YP_001049493.1 PFAM: FAD dependent oxidoreductase; KEGG: she:Shewmr4_2922 FAD dependent oxidoreductase YP_001049494.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; KEGG: shn:Shewana3_3100 transcriptional regulator, XRE family YP_001049495.1 KEGG: son:SO1485 hypothetical protein YP_001049496.1 PFAM: peptidase C26; KEGG: shn:Shewana3_3099 peptidase C26 YP_001049497.1 PFAM: glutamine synthetase, catalytic region; KEGG: shn:Shewana3_3098 glutamine synthetase, catalytic region YP_001049498.1 PFAM: extracellular solute-binding protein, family 1; KEGG: shm:Shewmr7_3000 extracellular solute-binding protein, family 1 YP_001049499.1 KEGG: shn:Shewana3_3096 spermidine/putrescine ABC transporter ATPase subunit; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001049500.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2998 binding-protein-dependent transport systems inner membrane component YP_001049501.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2997 binding-protein-dependent transport systems inner membrane component YP_001049502.1 PFAM: FAD dependent oxidoreductase; KEGG: shm:Shewmr7_2996 FAD dependent oxidoreductase YP_001049503.1 KEGG: son:SO1275 succinate-semialdehyde dehydrogenase (NADP+); TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_001049504.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_001049505.1 PFAM: luciferase family protein; KEGG: shn:Shewana3_3090 luciferase family protein YP_001049506.1 KEGG: son:SO1485 hypothetical protein YP_001049507.1 TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor, type I/II extracellular region; major facilitator superfamily MFS_1; KEGG: son:SO1277 proton-dependent oligopeptide transporter (POT) family protein YP_001049508.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_3021 integrase, catalytic region YP_001049509.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001049510.1 KEGG: sfr:Sfri_1308 hypothetical protein YP_001049511.1 PFAM: tryptophan halogenase; KEGG: sfr:Sfri_1309 tryptophan halogenase YP_001049512.1 SMART: transcription factor jumonji, jmjC domain protein; KEGG: sfr:Sfri_1310 transcription factor jumonji, JmjC domain protein YP_001049513.1 PFAM: SapC family protein; KEGG: sfr:Sfri_1311 SapC family protein YP_001049514.1 PFAM: tryptophan halogenase; KEGG: sfr:Sfri_1312 tryptophan halogenase YP_001049515.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_1313 TonB-dependent receptor, plug YP_001049516.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001049517.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001049518.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: sdn:Sden_2609 periplasmic binding protein/LacI transcriptional regulator YP_001049519.1 TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfr:Sfri_1315 sugar (glycoside-pentoside-hexuronide) transporter YP_001049520.1 PFAM: glycoside hydrolase, family 1; KEGG: sdn:Sden_2607 beta-glucosidase YP_001049521.1 TIGRFAM: glucose/galactose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfr:Sfri_1317 glucose/galactose transporter YP_001049522.1 PFAM: glycoside hydrolase, family 3 domain protein; KEGG: sfr:Sfri_1318 beta-glucosidase YP_001049523.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_001049524.1 PFAM: phage integrase family protein; KEGG: pst:PSPTO_0287 site-specific recombinase, phage integrase family YP_001049525.1 KEGG: hsa:30833 5', 3'-nucleotidase, cytosolic YP_001049526.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001049527.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001049528.1 KEGG: saz:Sama_0306 conserved hypothetical protein YP_001049529.1 KEGG: gvi:glr4338 hypothetical protein YP_001049530.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001049531.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001049532.1 TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma factor RpoD domain protein; PFAM: sigma-70 1.1 domain protein; sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70, non-essential domain protein; sigma-70 region 1.2; KEGG: shm:Shewmr7_2990 RNA polymerase, sigma 70 subunit, RpoD YP_001049533.1 KEGG: shm:Shewmr7_2989 DNA primase; TIGRFAM: DNA primase; PFAM: zinc finger, CHC2-family protein; TOPRIM domain protein; DNA primase DnaG, DnaB-binding; DNA primase catalytic core, N-terminal domain; SMART: Toprim sub domain protein YP_001049534.1 PFAM: GatB/Yqey domain protein; KEGG: son:SO1287 hypothetical protein YP_001049535.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001049536.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001049537.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001049538.1 TIGRFAM: dihydroneopterin aldolase; KEGG: son:SO1291 dihydroneopterin aldolase YP_001049539.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: she:Shewmr4_2901 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_001049540.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001049541.1 KEGG: shn:Shewana3_3078 ribosomal RNA large subunit methyltransferase A, putative YP_001049542.1 KEGG: shn:Shewana3_3077 major outer membrane lipoprotein, putative YP_001049543.1 PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase, HD sub domain; KEGG: shn:Shewana3_3076 metal dependent phosphohydrolase YP_001049544.1 PFAM: Peptidoglycan-binding domain 1 protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_2978 peptidoglycan-binding domain 1 protein YP_001049545.1 KEGG: shn:Shewana3_3074 general secretion pathway protein B YP_001049546.1 PFAM: Citrate transporter; KEGG: shn:Shewana3_3073 citrate transporter YP_001049547.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001049548.1 Catalyzes the conversion of carbamoyl phosphate and l-aspartate to yield orthophosphate and n-carbamoyl-l-aspartate YP_001049549.1 PFAM: Cl- channel, voltage-gated family protein; KEGG: shn:Shewana3_3069 Cl-channel, voltage-gated family protein YP_001049550.1 KEGG: she:Shewmr4_2890 hypothetical protein YP_001049551.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_001049552.1 PFAM: transposase, IS4 family protein; KEGG: son:SO3544 ISSod7, transposase YP_001049553.1 KEGG: she:Shewmr4_2888 hypothetical protein YP_001049554.1 KEGG: shn:Shewana3_3065 conserved hypothetical protein YP_001049555.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure YP_001049556.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001049557.1 PFAM: peptidase M23B; Opacity-associated protein A, N-terminal domain protein; KEGG: shn:Shewana3_3059 peptidase M23B YP_001049558.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001049559.1 KEGG: she:Shewmr4_2879 hypothetical protein YP_001049560.1 KEGG: she:Shewmr4_2878 hypothetical protein YP_001049561.1 PFAM: protein of unknown function UPF0126; KEGG: shn:Shewana3_3055 protein of unknown function UPF0126 YP_001049562.1 KEGG: shn:Shewana3_3054 conserved hypothetical protein YP_001049563.1 PFAM: purine and other phosphorylases, family 1; KEGG: shn:Shewana3_3052 purine and other phosphorylases, family 1 YP_001049564.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001049565.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_001049566.1 KEGG: shn:Shewana3_3048 conserved hypothetical radical SAM protein; TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001049567.1 PFAM: Hpt domain protein; KEGG: shn:Shewana3_3047 Hpt protein YP_001049568.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2950 transcriptional regulator, LysR family YP_001049569.1 KEGG: shn:Shewana3_3045 adenylate cyclase-related protein YP_001049570.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_001049571.1 hydrolyzes diadenosine polyphosphate YP_001049572.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; GAF domain protein; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein; KEGG: shm:Shewmr7_2946 PTSINtr with GAF domain, PtsP YP_001049573.1 PFAM: protein of unknown function DUF81; KEGG: shm:Shewmr7_2945 protein of unknown function DUF81 YP_001049574.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001049575.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001049576.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_001049577.1 KEGG: shn:Shewana3_3037 conserved hypothetical protein YP_001049578.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_001049579.1 PFAM: protein of unknown function DUF339; KEGG: shn:Shewana3_3035 protein of unknown function DUF339 YP_001049580.1 KEGG: shm:Shewmr7_2938 hypothetical protein YP_001049581.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001049582.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001049583.1 PFAM: Anti sigma-E protein RseA family protein; Anti sigma-E protein RseA domain protein; KEGG: she:Shewmr4_2853 anti sigma-E protein, RseA YP_001049584.1 PFAM: MucB/RseB family protein; KEGG: shn:Shewana3_3030 sigma E regulatory protein, MucB/RseB YP_001049585.1 PFAM: Positive regulator of sigma(E), RseC/MucC; KEGG: shn:Shewana3_3029 positive regulator of sigma E, RseC/MucC YP_001049586.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001049587.1 KEGG: shn:Shewana3_3027 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B YP_001049588.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001049589.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001049590.1 TIGRFAM: DNA repair protein RecO; PFAM: Recombination protein O, RecO; KEGG: son:SO1350 DNA repair protein RecO YP_001049591.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001049592.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001049593.1 PFAM: protein of unknown function DUF962; KEGG: shm:Shewmr7_2925 protein of unknown function DUF962 YP_001049594.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: shn:Shewana3_3020 protein of unknown function DUF21 YP_001049595.1 PFAM: cytochrome c assembly protein; KEGG: shn:Shewana3_3019 cytochrome c assembly protein YP_001049596.2 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_001049597.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001049598.1 Essential for efficient processing of 16S rRNA YP_001049599.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001049600.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001049601.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_001049602.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_001049603.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_001049604.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: shm:Shewmr7_2913 oxidoreductase FAD-binding domain protein YP_001049605.1 KEGG: shn:Shewana3_3009 conserved hypothetical protein YP_001049606.1 PFAM: sodium/hydrogen exchanger; KEGG: shm:Shewmr7_2911 sodium/hydrogen exchanger YP_001049607.1 TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: she:Shewmr4_2828 chorismate mutase YP_001049608.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: shn:Shewana3_1133 sigma 54 modulation protein/ribosomal protein S30EA YP_001049609.1 PFAM: cytochrome B561; KEGG: she:Shewmr4_1133 cytochrome b561 YP_001049610.1 PFAM: cytochrome c, class II; KEGG: shn:Shewana3_1135 cytochrome c, class II YP_001049611.1 TIGRFAM: trp operon repressor; PFAM: Trp repressor; KEGG: shn:Shewana3_1136 Trp operon repressor YP_001049612.1 KEGG: shn:Shewana3_1137 conserved hypothetical protein YP_001049613.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO3417 peptidyl-prolyl cis-trans isomerase SlyD YP_001049614.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001049615.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001049616.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001049617.1 KEGG: shm:Shewmr7_1212 hypothetical protein YP_001049618.1 PFAM: extracellular solute-binding protein, family 3; KEGG: shn:Shewana3_1143 extracellular solute-binding protein, family 3 YP_001049619.1 PFAM: peptidase S41; WD40 domain protein beta Propeller; SMART: PDZ/DHR/GLGF domain protein; KEGG: shn:Shewana3_1144 peptidase S41 YP_001049620.1 KEGG: shm:Shewmr7_1215 hypothetical protein YP_001049621.1 PFAM: OsmC family protein; KEGG: shm:Shewmr7_1216 OsmC family protein YP_001049622.1 KEGG: shn:Shewana3_1147 conserved hypothetical protein YP_001049623.1 PFAM: PepSY-associated TM helix domain protein; KEGG: shm:Shewmr7_1218 PepSY-associated TM helix domain protein YP_001049624.1 KEGG: shm:Shewmr7_1219 hypothetical protein YP_001049625.1 KEGG: shn:Shewana3_1150 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein YP_001049626.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: shm:Shewmr7_1221 sigma 54 modulation protein/ribosomal protein S30EA YP_001049627.1 KEGG: rso:RS05433 probable transmembrane protein YP_001049628.1 PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: shn:Shewana3_1152 two component transcriptional regulator, LuxR family YP_001049629.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region; KEGG: shn:Shewana3_1153 putative signal transduction histidine kinase YP_001049630.1 KEGG: sdn:Sden_3053 hypothetical protein YP_001049631.1 PFAM: Carotenoid oxygenase; KEGG: sdn:Sden_3052 carotenoid oxygenase YP_001049632.1 PFAM: protein of unknown function DUF28; KEGG: son:SO3401 hypothetical protein YP_001049633.1 PFAM: chemotaxis sensory transducer; KEGG: shn:Shewana3_1156 methyl-accepting chemotaxis sensory transducer YP_001049634.1 KEGG: shn:Shewana3_1157 conserved hypothetical protein YP_001049635.1 PFAM: regulatory protein, TetR; KEGG: she:Shewmr4_1157 transcriptional regulator, TetR family YP_001049636.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: shm:Shewmr7_1229 NADH:flavin oxidoreductase/NADH oxidase YP_001049637.1 KEGG: shm:Shewmr7_1230 peptidase S16, lon domain protein YP_001049638.1 KEGG: shn:Shewana3_1161 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001049639.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: shn:Shewana3_1162 DEAD/DEAH box helicase domain protein YP_001049640.1 KEGG: aeh:Mlg_2336 hypothetical protein YP_001049641.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001049642.1 KEGG: shn:Shewana3_0363 conserved hypothetical protein YP_001049643.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001049644.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001049645.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001049646.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001049648.1 PFAM: helix-turn-helix domain protein; KEGG: nar:Saro_2731 transcriptional regulator, XRE family YP_001049649.1 KEGG: ehi:82.t00025 Viral A-type inclusion protein repeat, putative Pfam: Nha1_C ERM KE2 WXG100 Vicilin_N TBPIP Myosin_tail_1 Filament YscO Rad50_zn_hook Bacillus_HBL HAP1_N Laminin_I EzrA DUF164 TPR_MLP1_2 DUF948 MpPF2 MSG Spectrin LMP PROSITE: GLU_RICH LYS_RICH YP_001049650.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001049651.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001049652.1 KEGG: bfr:BF2854 hypothetical protein YP_001049653.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001049654.1 KEGG: bps:BPSL0143 hypothetical protein YP_001049655.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001049656.1 PFAM: bacteriophage CI repressor; KEGG: shm:Shewmr7_0700 bacteriophage CI repressor YP_001049657.1 KEGG: yps:YPTB1770 putative regulator for prophage CP-933T (Escherichia coli O157:H7) YP_001049658.1 PFAM: phage regulatory CII family protein; KEGG: shm:Shewmr7_0702 phage regulatory CII family protein YP_001049659.1 KEGG: shm:Shewmr7_0705 hypothetical protein YP_001049662.1 KEGG: shm:Shewmr7_0708 hypothetical protein YP_001049663.1 KEGG: sdn:Sden_3277 hypothetical protein YP_001049664.1 PFAM: bacteriophage replication gene A; KEGG: spt:SPA2623 putative phage gene YP_001049665.1 PFAM: phage transcriptional activator, Ogr/delta; KEGG: shm:Shewmr7_0718 phage transcriptional activator, Ogr/delta YP_001049666.1 KEGG: eba:ebA2310 conserved hypothetical protein, predicted prevent-host-death family protein YP_001049668.1 TIGRFAM: phage portal protein, PBSX family; PFAM: phage portal protein; KEGG: shm:Shewmr7_0719 phage portal protein, PBSX family YP_001049669.1 PFAM: protein of unknown function DUF264; putative terminase ATPase subunit; KEGG: shm:Shewmr7_0720 protein of unknown function DUF264 YP_001049670.1 PFAM: phage capsid scaffolding; KEGG: shm:Shewmr7_0721 phage capsid scaffolding YP_001049671.1 TIGRFAM: phage major capsid protein, P2 family; PFAM: phage major capsid protein, P2; KEGG: shm:Shewmr7_0722 phage major capsid protein, P2 family YP_001049672.1 KEGG: shm:Shewmr7_0723 hypothetical protein YP_001049673.1 KEGG: shm:Shewmr7_0724 putative phage gene YP_001049674.1 KEGG: shm:Shewmr7_0725 hypothetical protein YP_001049675.1 KEGG: shm:Shewmr7_0726 hypothetical protein YP_001049676.1 KEGG: hch:HCH_06771 hypothetical protein YP_001049677.1 KEGG: shm:Shewmr7_0728 hypothetical protein YP_001049678.1 KEGG: shm:Shewmr7_0729 prophage PSPPH06, putative tail tube protein YP_001049679.1 KEGG: shm:Shewmr7_0730 transcriptional regulators, TraR/DksA family YP_001049680.1 PFAM: glycoside hydrolase, family 24; KEGG: sfr:Sfri_1671 glycoside hydrolase, family 24 YP_001049681.1 KEGG: son:SO2972 hypothetical protein YP_001049682.1 KEGG: sdn:Sden_3254 hypothetical protein YP_001049683.1 KEGG: shm:Shewmr7_0735 hypothetical protein YP_001049685.1 TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: shm:Shewmr7_0736 phage tail tape measure protein, TP901 family YP_001049686.1 KEGG: shm:Shewmr7_0737 hypothetical protein YP_001049687.1 KEGG: shm:Shewmr7_0738 putative bacteriophage protein YP_001049688.1 KEGG: shm:Shewmr7_0739 hypothetical protein YP_001049689.1 KEGG: shm:Shewmr7_0740 hypothetical protein YP_001049690.1 KEGG: shm:Shewmr7_0741 hypothetical protein YP_001049691.1 KEGG: shm:Shewmr7_0742 hypothetical protein YP_001049692.1 KEGG: shm:Shewmr7_0743 hypothetical protein YP_001049693.1 KEGG: shm:Shewmr7_0743 hypothetical protein YP_001049694.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001049695.1 PFAM: cyclase/dehydrase; KEGG: shn:Shewana3_2951 cyclase/dehydrase YP_001049696.1 PFAM: protein of unknown function UPF0125; KEGG: shn:Shewana3_2950 protein of unknown function UPF0125 YP_001049697.1 PFAM: SmpA/OmlA domain protein; KEGG: shm:Shewmr7_2851 SmpA/OmlA domain protein YP_001049698.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: shn:Shewana3_2948 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase YP_001049699.1 KEGG: son:SO1479 hypothetical protein YP_001049700.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO1480 GGDEF family protein YP_001049701.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: son:SO1481 glutathione-regulated potassium-efflux system protein YP_001049702.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shn:Shewana3_2944 TonB-dependent receptor YP_001049703.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001049704.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: son:SO1484 isocitrate lyase YP_001049705.1 PFAM: thioesterase superfamily protein; KEGG: shn:Shewana3_2941 thioesterase superfamily protein YP_001049706.1 KEGG: son:SO1487 hypothetical protein YP_001049707.1 KEGG: she:Shewmr4_2763 hypothetical protein YP_001049708.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: shm:Shewmr7_2840 iron-containing alcohol dehydrogenase YP_001049709.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001049710.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_001049711.1 catalyzes the formation of betaine from betaine aldehyde YP_001049712.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_001049713.1 KEGG: sfr:Sfri_1945 putative transporter, BCCT family protein YP_001049714.1 KEGG: sfr:Sfri_1944 hypothetical protein YP_001049715.1 PFAM: regulatory protein, MarR; KEGG: shn:Shewana3_2937 transcriptional regulator, MarR family YP_001049716.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: shn:Shewana3_2936 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001049717.1 KEGG: shn:Shewana3_2935 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase, family 77 YP_001049718.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001049719.1 KEGG: shm:Shewmr7_2835 glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001049720.1 KEGG: shn:Shewana3_2932 glycogen/starch/alpha-glucan phosphorylases; TIGRFAM: glycogen/starch/alpha-glucan phosphorylases; PFAM: glycosyl transferase, family 35 YP_001049721.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001049722.1 PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein; KEGG: she:Shewmr4_2754 starch synthase YP_001049723.1 KEGG: shn:Shewana3_2929 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; 5TM Receptors of the LytS-YhcK type, transmembrane region; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001049724.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO1501 ATP-dependent RNA helicase, DEAD box family YP_001049725.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein; KEGG: shn:Shewana3_2927 cobalamin synthesis protein, P47K YP_001049726.1 SMART: extracellular solute-binding protein, family 3; KEGG: son:SO1503 ABC transporter, periplasmic substrate-binding protein, putative YP_001049727.1 KEGG: shn:Shewana3_2925 conserved hypothetical protein YP_001049728.1 PFAM: major facilitator superfamily MFS_1; KEGG: shn:Shewana3_2924 major facilitator superfamily MFS_1 YP_001049729.1 PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO1506 MATE efflux family protein YP_001049730.1 KEGG: shn:Shewana3_2922 conserved hypothetical protein YP_001049731.1 KEGG: son:SO1508 hypothetical protein YP_001049732.1 KEGG: shm:Shewmr7_2813 hypothetical protein YP_001049733.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_2812 AAA ATPase, central domain protein YP_001049734.1 PFAM: Integrase, catalytic region; KEGG: sfr:Sfri_4013 integrase, catalytic region YP_001049735.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfr:Sfri_4014 transposase IS3/IS911 family protein YP_001049736.1 KEGG: shm:Shewmr7_2812 AAA ATPase, central domain protein YP_001049737.1 PFAM: protein of unknown function DUF162; KEGG: she:Shewmr4_2738 protein of unknown function DUF162 YP_001049738.1 PFAM: protein of unknown function DUF162; KEGG: shm:Shewmr7_2810 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001049739.1 PFAM: protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: she:Shewmr4_2736 protein of unknown function DUF224, cysteine-rich region domain protein YP_001049740.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; FAD linked oxidase domain protein; KEGG: shn:Shewana3_2905 FAD linked oxidase domain protein YP_001049741.1 PFAM: L-lactate permease; KEGG: shm:Shewmr7_2807 L-lactate permease YP_001049742.1 catalyzes the phosphorylation of NAD to NADP YP_001049743.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001049744.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001049745.1 PFAM: Polyprenyl synthetase; KEGG: son:SO1526 geranyltranstransferase YP_001049746.1 TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII, small subunit; KEGG: shn:Shewana3_2899 exodeoxyribonuclease VII, small subunit YP_001049747.1 Homologous to MotA in E. coli and Salmonella. With PomB forms the ion channels that couple flagellar rotation to sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. YP_001049748.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; Vibrio parahaemolyticus protein is associated with the polar flagella YP_001049749.1 Required for the synthesis of the thiazole moiety YP_001049750.1 KEGG: shm:Shewmr7_2796 hypothetical protein YP_001049751.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_001049752.1 KEGG: shm:Shewmr7_2794 hypothetical protein YP_001049753.1 PFAM: protein of unknown function DUF423; KEGG: shn:Shewana3_2892 protein of unknown function DUF423 YP_001049754.1 KEGG: son:SO1536 hypothetical protein YP_001049755.1 catalyzes the formation of 2-oxoglutarate from isocitrate YP_001049756.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; KEGG: she:Shewmr4_2719 peptidase S9, prolyl oligopeptidase active site domain protein YP_001049757.1 KEGG: she:Shewmr4_2717 hypothetical protein YP_001049758.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_001049759.1 PFAM: conserved hypothetical protein 730; KEGG: son:SO1550 hypothetical protein YP_001049760.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_2782 diguanylate cyclase YP_001049761.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_2781 TPR repeat-containing protein YP_001049762.1 PFAM: peptidase M61 domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: shn:Shewana3_2882 peptidase M61 domain protein YP_001049763.1 Required for efficient pilin antigenic variation YP_001049764.1 PFAM: porin, Gram-negative type; KEGG: she:Shewmr4_2710 porin, gram-negative type YP_001049765.1 TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shn:Shewana3_2879 two component transcriptional regulator, winged helix family YP_001049766.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: shn:Shewana3_2878 putative PAS/PAC sensor protein YP_001049767.1 TIGRFAM: phosphate binding protein; KEGG: shm:Shewmr7_2775 phosphate binding protein YP_001049768.1 PFAM: Integrase, catalytic region; KEGG: shm:Shewmr7_3980 integrase, catalytic region YP_001049769.1 KEGG: shm:Shewmr7_3734 transposase YP_001049770.1 PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: son:SO1561 peptidase, M1 family YP_001049771.1 PFAM: glutathione peroxidase; KEGG: she:Shewmr4_2705 glutathione peroxidase YP_001049772.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: she:Shewmr4_2704 MgtE intracellular region YP_001049773.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_2873 GCN5-related N-acetyltransferase YP_001049774.1 PFAM: YfaZ family protein; KEGG: she:Shewmr4_2702 YfaZ family protein YP_001049775.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: shn:Shewana3_2871 protein of unknown function DUF6, transmembrane YP_001049776.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Diverse 7TM receptor, extracellular region 2; Diverse 7TM receptor, transmembrane region; KEGG: shn:Shewana3_2870 diguanylate cyclase YP_001049777.1 KEGG: shn:Shewana3_2869 conserved hypothetical protein YP_001049778.1 KEGG: shn:Shewana3_2868 conserved hypothetical protein YP_001049779.1 PFAM: Fmu (Sun) domain protein; KEGG: son:SO1575 NOL1/NOP2/sun family putative RNA methylase YP_001049780.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: shn:Shewana3_2866 glutathione S-transferase, N-terminal domain protein YP_001049781.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: shn:Shewana3_2865 glutathione S-transferase, N-terminal domain protein YP_001049782.1 PFAM: regulatory protein, TetR; KEGG: son:SO1578 transcriptional regulator, TetR family YP_001049783.1 KEGG: she:Shewmr4_2693 hypothetical protein YP_001049784.1 TIGRFAM: TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shn:Shewana3_2862 TonB-dependent heme/hemoglobin receptor family protein YP_001049785.1 PFAM: PhnA protein-like; SMART: PhnA protein N-terminal, proteobacterial; KEGG: son:SO1581 PhnA protein YP_001049786.1 PFAM: major facilitator superfamily MFS_1; KEGG: shn:Shewana3_2860 major facilitator superfamily MFS_1 YP_001049787.1 PFAM: regulatory protein, MarR; KEGG: shn:Shewana3_2859 transcriptional regulator, MarR family YP_001049788.1 PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: son:SO1583 hypothetical protein YP_001049789.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: sdn:Sden_2638 chemotaxis sensory transducer YP_001049790.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: shn:Shewana3_2857 fumarylacetoacetate (FAA) hydrolase YP_001049791.1 KEGG: son:SO1588 hypothetical protein YP_001049792.1 PFAM: glycoside hydrolase, family 20; Carbohydrate-binding, chitobiase/hexosaminidase-type domain protein; KEGG: saz:Sama_0943 beta-N-acetylhexosaminidase YP_001049793.1 PFAM: ROK family protein; KEGG: bfr:BF1751 ROK family transcriptional repressor YP_001049794.1 PFAM: major facilitator superfamily MFS_1; KEGG: aba:Acid345_0005 major facilitator superfamily (MFS) transporter YP_001049795.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: hch:HCH_04392 hypothetical protein YP_001049796.1 PFAM: tryptophan halogenase; KEGG: pat:Patl_0803 tryptophan halogenase YP_001049797.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: cps:CPS_1021 TonB-dependent receptor YP_001049798.1 PFAM: polysaccharide deacetylase; KEGG: vpa:VP2638 deacetylase DA1 YP_001049799.1 KEGG: son:SO1589 hypothetical protein YP_001049800.1 KEGG: son:SO1590 hypothetical protein YP_001049801.1 PFAM: transposase, IS4 family protein; KEGG: son:SO3544 ISSod7, transposase YP_001049802.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria; KEGG: shm:Shewmr7_2744 transport-associated YP_001049803.1 KEGG: shn:Shewana3_2850 hypothetical protein YP_001049804.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shn:Shewana3_2849 sigma54 specific transcriptional regulator, fis family YP_001049805.1 KEGG: pat:Patl_1754 hypothetical protein YP_001049806.1 PFAM: Dual specificity protein phosphatase; diacylglycerol kinase, catalytic region; KEGG: shm:Shewmr7_2741 diacylglycerol kinase, catalytic region YP_001049807.1 KEGG: shn:Shewana3_2847 conserved hypothetical protein YP_001049808.1 PFAM: protein of unknown function DUF1328; KEGG: shm:Shewmr7_2739 protein of unknown function DUF1328 YP_001049809.1 KEGG: shm:Shewmr7_2736 2-nitropropane dioxygenase, NPD YP_001049810.1 PFAM: beta-ketoacyl synthase; Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; KEGG: she:Shewmr4_2668 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ YP_001049811.1 KEGG: shn:Shewana3_2841 omega-3 polyunsaturated fatty acid synthase PfaB YP_001049812.1 PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; KR; KEGG: she:Shewmr4_2666 beta-ketoacyl synthase YP_001049813.1 KEGG: shm:Shewmr7_2732 transcriptional regulator, putative YP_001049814.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: shm:Shewmr7_2731 4'-phosphopantetheinyl transferase YP_001049815.1 KEGG: shn:Shewana3_2837 lipoprotein, putative YP_001049816.1 PFAM: beta-lactamase domain protein; KEGG: son:SO1606 metallo-beta-lactamase superfamily protein YP_001049817.1 PFAM: regulatory protein, LysR; KEGG: son:SO1607 transcriptional regulator, LysR family YP_001049818.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_001049819.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_001049820.1 KEGG: shn:Shewana3_2833 conserved hypothetical protein YP_001049821.1 KEGG: shm:Shewmr7_2725 hypothetical protein YP_001049822.1 KEGG: son:SO1612 hypothetical protein YP_001049823.1 KEGG: son:SO1613 hypothetical protein YP_001049824.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_2829 GCN5-related N-acetyltransferase YP_001049825.1 KEGG: son:SO1615 hypothetical protein YP_001049826.1 KEGG: son:SO1617 hypothetical protein YP_001049827.1 KEGG: shm:Shewmr7_2719 hypothetical protein YP_001049828.1 PFAM: protein of unknown function DUF446; KEGG: shm:Shewmr7_2718 protein of unknown function DUF446 YP_001049829.1 PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_2717 pseudouridylate synthase YP_001049830.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001049831.1 TIGRFAM: PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS, EIIB protein; phosphotransferase system, EIIC; KEGG: she:Shewmr4_2648 PTS system, glucose-like IIB subunint YP_001049832.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001049833.1 PFAM: CBS domain containing protein; GAF domain protein; metal-dependent phosphohydrolase, HD sub domain; HDOD; SMART: metal-dependent phosphohydrolase, HD region; KEGG: shn:Shewana3_2820 metal dependent phosphohydrolase YP_001049834.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001049835.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001049836.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001049837.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001049838.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001049839.1 Catalyzes the phosphorylation of UMP to UDP YP_001049840.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001049841.1 KEGG: son:SO1633 undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_001049842.1 PFAM: phosphatidate cytidylyltransferase; KEGG: shn:Shewana3_2810 phosphatidate cytidylyltransferase YP_001049843.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001049844.1 TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: shn:Shewana3_2808 putative membrane-associated zinc metalloprotease YP_001049845.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: shm:Shewmr7_2700 surface antigen (D15) YP_001049846.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: shn:Shewana3_2806 outer membrane chaperone Skp (OmpH) YP_001049847.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001049848.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001049849.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001049850.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001049851.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001049852.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001049853.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; tRNA(Ile)-lysidine synthetase domain protein; KEGG: shm:Shewmr7_2692 tRNA(Ile)-lysidine synthetase YP_001049854.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: she:Shewmr4_2624 diguanylate cyclase YP_001049855.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; sodium/hydrogen exchanger; KEGG: shn:Shewana3_2797 potassium efflux system protein YP_001049856.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: shm:Shewmr7_2689 cold-shock DNA-binding domain protein YP_001049857.1 PFAM: protein of unknown function DUF885; KEGG: shn:Shewana3_2796 protein of unknown function DUF885 YP_001049858.1 PFAM: SNF2-related protein; helicase domain protein; zinc finger, SWIM domain protein; SMART: DEAD-like helicases-like; KEGG: shn:Shewana3_2795 SNF2-related protein YP_001049859.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; KEGG: she:Shewmr4_2619 PHP C-terminal domain protein YP_001049860.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; KEGG: she:Shewmr4_2618 dTDP-4-dehydrorhamnose reductase YP_001049861.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: shm:Shewmr7_2684 3'(2'),5'-bisphosphate nucleotidase YP_001049862.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_001049863.1 PFAM: protein of unknown function DUF218; KEGG: she:Shewmr4_2615 protein of unknown function DUF218 YP_001049864.1 KEGG: shm:Shewmr7_2681 hypothetical protein YP_001049865.1 KEGG: shn:Shewana3_2787 decaheme cytochrome c YP_001049866.1 PFAM: regulatory protein, LysR; KEGG: shn:Shewana3_2786 transcriptional regulator, LysR family YP_001049867.1 PFAM: protein of unknown function DUF583; KEGG: shn:Shewana3_2785 protein of unknown function DUF583 YP_001049868.1 TIGRFAM: ferredoxin-type protein NapF; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO1663 ferredoxin-type protein NapF YP_001049869.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: she:Shewmr4_2609 UDP-glucose 4-epimerase YP_001049870.1 KEGG: son:SO1665 UTP--glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase YP_001049871.1 phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin YP_001049872.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_001049873.1 PFAM: sigma-54 factor, interaction domain-containing protein; amino acid-binding ACT domain protein; SMART: AAA ATPase; KEGG: son:SO1669 transcriptional regulatory protein TyrR YP_001049874.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: shn:Shewana3_2778 fumarylacetoacetate (FAA) hydrolase YP_001049875.1 TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: shn:Shewana3_2777 response regulator receiver protein YP_001049876.1 PFAM: protein of unknown function DUF925; KEGG: son:SO1672 hypothetical protein YP_001049877.1 receptor for colicin S4 YP_001049878.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: son:SO1674 short chain dehydrogenase family protein YP_001049879.1 KEGG: shn:Shewana3_2773 conserved hypothetical protein YP_001049880.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_001049881.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: aha:AHA_3859 hemolysin secretion protein YP_001049882.1 KEGG: shm:Shewmr7_2664 acetyl-CoA acetyltransferases; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase YP_001049883.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: shn:Shewana3_2770 methylmalonate-semialdehyde dehydrogenase YP_001049884.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: shn:Shewana3_2769 acyl-CoA dehydrogenase domain protein YP_001049885.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001049886.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: shm:Shewmr7_2660 enoyl-CoA hydratase/isomerase YP_001049887.1 KEGG: shn:Shewana3_2766 3-hydroxyisobutyrate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding YP_001049888.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001049889.1 KEGG: shm:Shewmr7_2657 hypothetical protein YP_001049890.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; KEGG: she:Shewmr4_2589 peptidase S9, prolyl oligopeptidase active site domain protein YP_001049891.1 PFAM: regulatory protein, MerR; KEGG: shm:Shewmr7_2655 transcriptional regulator, MerR family YP_001049892.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: shm:Shewmr7_2654 copper-translocating P-type ATPase YP_001049893.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_2653 ABC transporter related YP_001049894.1 PFAM: Lipocalin-related protein and Bos/Can/Equ allergen; Lipocalin family protein; KEGG: son:SO1691 lipoprotein Blc YP_001049895.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: shn:Shewana3_2759 protein of unknown function DUF6, transmembrane YP_001049896.1 KEGG: shn:Shewana3_2759 protein of unknown function DUF6, transmembrane YP_001049897.1 PFAM: FAD linked oxidase domain protein; KEGG: she:Shewmr4_2583 FAD linked oxidase domain protein YP_001049898.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001049899.1 KEGG: son:SO1694 FAD-binding protein YP_001049900.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shn:Shewana3_2757 diguanylate cyclase YP_001049901.1 KEGG: shn:Shewana3_2756 conserved hypothetical protein YP_001049902.1 PFAM: transcriptional regulator domain protein; Tetratricopeptide TPR_2 repeat protein; KEGG: shn:Shewana3_2755 transcriptional regulator, CadC YP_001049903.1 KEGG: son:SO1700 hypothetical protein YP_001049904.1 KEGG: shn:Shewana3_2753 conserved hypothetical protein YP_001049905.1 KEGG: shm:Shewmr7_2644 hypothetical protein YP_001049906.1 PFAM: regulatory protein, TetR; KEGG: shn:Shewana3_2751 transcriptional regulator, TetR family YP_001049907.1 PFAM: secretion protein HlyD family protein; KEGG: shn:Shewana3_2750 secretion protein HlyD family protein YP_001049908.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shn:Shewana3_2749 ABC transporter related YP_001049909.1 PFAM: ABC-2 type transporter; KEGG: shn:Shewana3_2748 ABC-2 type transporter YP_001049910.1 TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; KEGG: ilo:IL0811 signal peptidase I YP_001049911.1 PFAM: acetyl-CoA hydrolase/transferase; KEGG: she:Shewmr4_2572 acetyl-CoA hydrolase/transferase YP_001049912.1 KEGG: shn:Shewana3_2746 hypothetical protein YP_001049913.1 PFAM: beta-lactamase; KEGG: sus:Acid_1314 beta-lactamase YP_001049914.1 PFAM: GCN5-related N-acetyltransferase; KEGG: aha:AHA_1360 acetyltransferase, GNAT family YP_001049915.1 PFAM: protein of unknown function DUF1415; KEGG: shm:Shewmr7_2635 protein of unknown function DUF1415 YP_001049916.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shm:Shewmr7_2634 lysine exporter protein (LysE/YggA) YP_001049917.1 KEGG: she:Shewmr4_2566 hypothetical protein YP_001049918.1 KEGG: she:Shewmr4_2564 hypothetical protein YP_001049919.1 KEGG: shm:Shewmr7_2630 putative esterase YP_001049920.1 PFAM: amino acid-binding ACT domain protein; KEGG: shn:Shewana3_2735 amino acid-binding ACT domain protein YP_001049921.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2627 binding-protein-dependent transport systems inner membrane component YP_001049922.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: she:Shewmr4_2559 phosphate ABC transporter, inner membrane subunit PstA YP_001049923.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001049924.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_001049925.1 KEGG: she:Shewmr4_2556 hypothetical protein YP_001049927.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: son:SO1734 glyoxalase family protein YP_001049928.1 KEGG: shm:Shewmr7_2620 hypothetical protein YP_001049929.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: shn:Shewana3_2719 choline/carnitine/betaine transporter YP_001049930.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: shn:Shewana3_2718 HNH endonuclease YP_001049931.1 PFAM: protein of unknown function DUF1289; KEGG: shm:Shewmr7_2617 protein of unknown function DUF1289 YP_001049932.1 KEGG: son:SO1741 hypothetical protein YP_001049933.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001049934.1 PFAM: alpha/beta hydrolase fold; KEGG: shn:Shewana3_2714 alpha/beta hydrolase fold YP_001049935.1 Catalyzes the specific recognition and activation of amino acids during peptide synthesis YP_001049936.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility C-terminal domain; KEGG: shn:Shewana3_2712 3-beta hydroxysteroid dehydrogenase/isomerase YP_001049937.1 KEGG: son:SO1746 hypothetical protein YP_001049938.1 TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor, type I/II extracellular region; major facilitator superfamily MFS_1; KEGG: sdn:Sden_0945 amino acid/peptide transporter YP_001049939.1 KEGG: saz:Sama_1098 hypothetical protein YP_001049940.1 PFAM: Integral membrane protein TerC; KEGG: son:SO1747 membrane protein, putative YP_001049941.1 KEGG: shn:Shewana3_2709 conserved hypothetical protein YP_001049942.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1750 ABC transporter, ATP-binding protein YP_001049943.1 KEGG: son:SO1751 hypothetical protein YP_001049944.1 PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: she:Shewmr4_2541 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I YP_001049945.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: shn:Shewana3_2706 glyoxalase/bleomycin resistance protein/dioxygenase YP_001049946.1 PFAM: transcription activator, effector binding; KEGG: shn:Shewana3_2705 transcription activator, effector binding YP_001049947.1 PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein; KEGG: she:Shewmr4_2538 helix-turn-helix, type 11 domain protein YP_001049948.1 PFAM: Aerolysin/hemolysin/leukocidin toxin; KEGG: sdn:Sden_2258 aerolysin/hemolysin/leukocidin toxin YP_001049949.1 PFAM: branched-chain amino acid transport; KEGG: son:SO1759 hypothetical protein YP_001049950.1 PFAM: AzlC family protein; KEGG: shn:Shewana3_2694 AzlC family protein YP_001049951.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: son:SO1762 transcriptional regulator, AraC/XylS family YP_001049952.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: son:SO1763 streptogramin A acetyl transferase YP_001049953.1 KEGG: son:SO1765 hypothetical protein YP_001049954.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001049955.1 KEGG: she:Shewmr4_2525 hypothetical protein YP_001049956.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); HAD-superfamily subfamily IB hydrolase, TIGR01490; KEGG: vpa:VPA0093 hypothetical protein YP_001049957.1 PFAM: Pyridoxal-dependent decarboxylase; KEGG: she:Shewmr4_2520 pyridoxal-dependent decarboxylase YP_001049958.1 PFAM: glycerate kinase; KEGG: shm:Shewmr7_2587 glycerate kinase YP_001049959.1 PFAM: Gluconate transporter; Citrate transporter; KEGG: shm:Shewmr7_2586 gluconate transporter YP_001049960.1 PFAM: Catalase domain protein; KEGG: shn:Shewana3_2683 catalase domain protein YP_001049961.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001049962.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001049963.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: mpu:MYPU_3960 type III restriction-modification system: methylase YP_001049964.1 TIGRFAM: mobile mystery protein B; PFAM: filamentation induced by cAMP protein Fic; KEGG: shn:Shewana3_4245 mobile mystery protein B YP_001049965.1 TIGRFAM: mobile mystery protein A; PFAM: helix-turn-helix domain protein; KEGG: shn:Shewana3_4246 transcriptional regulator, XRE family YP_001049966.1 PFAM: phage integrase family protein; KEGG: son:SOA0045 site-specific recombinase, phage integrase family YP_001049967.1 PFAM: phage integrase family protein; KEGG: son:SOA0044 site-specific recombinase, phage integrase family YP_001049968.1 KEGG: shm:Shewmr7_2582 phage SPO1 DNA polymerase domain protein YP_001049969.1 KEGG: shm:Shewmr7_2581 hypothetical protein YP_001049970.1 KEGG: shn:Shewana3_2678 outer membrane protein precursor MtrB YP_001049971.1 TIGRFAM: cytochrome C family protein; KEGG: son:SO1777 decaheme cytochrome c MtrA YP_001049972.1 KEGG: shn:Shewana3_2676 decaheme cytochrome c YP_001049973.1 KEGG: shn:Shewana3_2675 decaheme cytochrome c YP_001049974.1 KEGG: shn:Shewana3_2674 decaheme cytochrome c MtrF YP_001049975.1 KEGG: she:Shewmr4_2507 outer membrane protein, putative YP_001049976.1 TIGRFAM: cytochrome C family protein; KEGG: shn:Shewana3_2672 cytochrome c family protein YP_001049977.1 PFAM: FeoA family protein; KEGG: shn:Shewana3_2671 FeoA family protein YP_001049978.1 TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; nucleoside recognition domain protein; Miro domain protein; KEGG: shm:Shewmr7_2572 ferrous iron transport protein B YP_001049979.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001049980.1 PFAM: protein of unknown function DUF1282; KEGG: she:Shewmr4_2502 protein of unknown function DUF1282 YP_001049981.1 PFAM: tRNA--hydroxylase; KEGG: shn:Shewana3_2667 tRNA hydroxylase YP_001049982.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_001049983.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: son:SO1790 peptidyl-prolyl cis-trans isomerase B YP_001049984.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001049985.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001049986.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001049987.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001049988.1 binds and unfolds substrates as part of the ClpXP protease YP_001049989.1 KEGG: son:SO1796 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16, lon domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001049990.1 PFAM: histone family protein DNA-binding protein; KEGG: shm:Shewmr7_2560 histone family protein DNA-binding protein YP_001049991.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: shn:Shewana3_2657 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001049992.1 PFAM: TOBE domain protein; KEGG: shn:Shewana3_2656 molybdenum-pterin binding YP_001049993.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_001049994.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1801 peptide ABC transporter, ATP-binding protein YP_001049995.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; KEGG: son:SO1802 peptide ABC transporter, ATP-binding protein YP_001049996.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shn:Shewana3_2652 binding-protein-dependent transport systems inner membrane component YP_001049997.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shn:Shewana3_2651 binding-protein-dependent transport systems inner membrane component YP_001049998.1 PFAM: extracellular solute-binding protein, family 5; KEGG: shn:Shewana3_2650 acetate kinase YP_001049999.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_2551 transcriptional regulator, fis family YP_001050000.1 PFAM: PspA/IM30 family protein; KEGG: son:SO1807 phage shock protein A YP_001050001.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_001050002.1 PFAM: PspC domain protein; KEGG: shm:Shewmr7_2548 phage shock protein C, PspC YP_001050003.1 PFAM: protein of unknown function DUF463, YcjX family protein; KEGG: she:Shewmr4_2479 protein of unknown function DUF463, YcjX family protein YP_001050004.1 PFAM: conserved hypothetical protein 1620; KEGG: shn:Shewana3_2644 conserved hypothetical protein 1620 YP_001050005.1 KEGG: she:Shewmr4_2477 methionine gamma-lyase; TIGRFAM: methionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001050006.1 TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; SMART: Helix-hairpin-helix DNA-binding, class 1; KEGG: son:SO1813 DNA-binding protein, putative YP_001050007.1 KEGG: she:Shewmr4_2475 hypothetical protein YP_001050008.1 PFAM: histone deacetylase superfamily; KEGG: son:SO1815 histone deacetylase/AcuC/AphA family protein YP_001050009.1 KEGG: shn:Shewana3_2633 conserved hypothetical protein YP_001050010.1 KEGG: son:SO1817 primosomal replication protein N'', putative YP_001050011.1 PFAM: protein of unknown function DUF81; KEGG: shm:Shewmr7_2539 protein of unknown function DUF81 YP_001050012.1 helicase involved in DNA repair and perhaps also replication YP_001050013.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_001050014.1 PFAM: porin, Gram-negative type; KEGG: she:Shewmr4_2468 porin, gram-negative type YP_001050015.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pat:Patl_2993 TonB-dependent receptor YP_001050016.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: pha:PSHAb0158 putative TonB-dependent receptor with TonB-box YP_001050017.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001050018.1 PFAM: transposase, IS4 family protein; KEGG: son:SO4437 ISSod3, transposase YP_001050019.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001050020.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001050021.1 KEGG: shn:Shewana3_2626 conserved hypothetical protein YP_001050022.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: shn:Shewana3_2625 MotA/TolQ/ExbB proton channel YP_001050023.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: she:Shewmr4_2462 MotA/TolQ/ExbB proton channel YP_001050024.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: shn:Shewana3_2623 biopolymer transport protein ExbD/TolR YP_001050025.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: shn:Shewana3_2622 TonB family protein YP_001050026.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: shn:Shewana3_2621 TPR repeat-containing protein YP_001050027.1 PFAM: GGDEF domain containing protein; KEGG: son:SO1830 GGDEF domain protein YP_001050028.1 PFAM: protein of unknown function DUF885; KEGG: shn:Shewana3_2619 protein of unknown function DUF885 YP_001050029.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: shn:Shewana3_2618 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001050030.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_2455 GCN5-related N-acetyltransferase YP_001050031.1 KEGG: shn:Shewana3_2616 RNA-binding S4 domain protein YP_001050032.1 PFAM: protein of unknown function DUF1260; KEGG: shm:Shewmr7_2523 protein of unknown function DUF1260 YP_001050033.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shn:Shewana3_2614 transcriptional regulator, LysR family YP_001050034.1 PFAM: protein of unknown function DUF81; KEGG: shn:Shewana3_2613 protein of unknown function DUF81 YP_001050035.1 TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase; KEGG: she:Shewmr4_2450 nuclease SbcCD, D subunit YP_001050036.1 PFAM: SMC domain protein; KEGG: shn:Shewana3_2611 exonuclease SbcC, putative YP_001050037.1 PFAM: peptidase M23B; KEGG: shm:Shewmr7_2518 peptidase M23B YP_001050038.1 KEGG: shn:Shewana3_2609 conserved hypothetical protein YP_001050039.1 PFAM: protein of unknown function DUF45; KEGG: son:SO2840 hypothetical protein YP_001050040.1 KEGG: shn:Shewana3_2607 conserved hypothetical protein YP_001050041.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: she:Shewmr4_2444 DEAD/DEAH box helicase domain protein YP_001050042.1 PFAM: Patatin; KEGG: shn:Shewana3_2605 patatin YP_001050043.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ppr:PBPRB1158 hypothetical alcohol dehydrogenase, zinc-containing YP_001050044.1 PFAM: regulatory protein, MarR; KEGG: ppr:PBPRB1157 putative transcriptional regulator, MarR family YP_001050045.1 KEGG: shm:Shewmr7_2512 hypothetical protein YP_001050046.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_001050047.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_001050048.1 KEGG: shn:Shewana3_2601 conserved hypothetical protein YP_001050049.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_001050050.1 KEGG: shm:Shewmr7_2507 hypothetical protein YP_001050051.1 KEGG: shn:Shewana3_2598 conserved hypothetical protein YP_001050052.1 KEGG: shn:Shewana3_2596 conserved hypothetical protein YP_001050053.1 unknown function; when overproduced it confers drug-resistance YP_001050054.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type, transmembrane region; KEGG: shn:Shewana3_2593 signal transduction histidine kinase, LytS YP_001050055.1 KEGG: shm:Shewmr7_2500 hypothetical protein YP_001050056.1 KEGG: shm:Shewmr7_2499 RepA domain protein YP_001050057.1 KEGG: shn:Shewana3_2590 conserved hypothetical protein YP_001050058.1 PFAM: type IV pilus assembly PilZ; KEGG: son:SO2807 hypothetical protein YP_001050059.1 PFAM: phosphate-starvation-inducible E; KEGG: shn:Shewana3_2588 phosphate-starvation-inducible E YP_001050060.1 PFAM: NnrS family protein; KEGG: shn:Shewana3_2587 NnrS family protein YP_001050061.1 KEGG: son:SO2804 hypothetical protein YP_001050062.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG: shn:Shewana3_2585 DNA internalization-related competence protein ComEC/Rec2 YP_001050063.1 KEGG: shn:Shewana3_2584 lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; TIGRFAM: lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001050064.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001050065.1 PFAM: protein of unknown function DUF343; KEGG: shn:Shewana3_2582 protein of unknown function DUF343 YP_001050066.1 KEGG: she:Shewmr4_2419 lipoprotein, putative YP_001050067.1 KEGG: she:Shewmr4_2418 hypothetical protein YP_001050068.1 PFAM: glutaredoxin; Glutathione S-transferase, N-terminal domain; KEGG: shn:Shewana3_2579 glutaredoxin YP_001050069.1 PFAM: protein of unknown function DUF748; KEGG: shn:Shewana3_2578 protein of unknown function DUF748 YP_001050070.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: son:SO2795 glyoxalase family protein YP_001050071.1 KEGG: she:Shewmr4_2414 hypothetical protein YP_001050072.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: son:SO2793 glyoxalase family protein YP_001050073.1 PFAM: protein of unknown function DUF1289; KEGG: she:Shewmr4_2412 protein of unknown function DUF1289 YP_001050074.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001050075.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_001050077.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pen:PSEEN2698 hypothetical protein YP_001050078.1 KEGG: sil:SPO3420 hypothetical protein YP_001050079.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: rpc:RPC_3420 glutathione-dependent formaldehyde-activating, GFA YP_001050081.1 PFAM: DinB family protein; KEGG: pfl:PFL_3815 DinB family protein YP_001050082.1 PFAM: major facilitator superfamily MFS_1; KEGG: pfo:Pfl_3663 twin-arginine translocation pathway signal YP_001050083.1 PFAM: helix-turn-helix, HxlR type; KEGG: pfl:PFL_3943 hypothetical protein YP_001050084.1 KEGG: she:Shewmr4_2409 hypothetical protein YP_001050085.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_001050086.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: shn:Shewana3_2569 cold-shock DNA-binding domain protein YP_001050087.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: shn:Shewana3_2568 sulphate transporter YP_001050088.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: she:Shewmr4_2405 ribonuclease, Rne/Rng family YP_001050089.1 KEGG: shn:Shewana3_2566 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001050090.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_2473 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_001050091.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: son:SO2782 maf protein, putative YP_001050092.1 PFAM: protein of unknown function DUF177; KEGG: shn:Shewana3_2563 protein of unknown function DUF177 YP_001050093.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001050094.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001050095.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001050096.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein; KEGG: shm:Shewmr7_2467 malonyl CoA-acyl carrier protein transacylase YP_001050097.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: son:SO2776 3-oxoacyl-[acyl-carrier protein] reductase YP_001050098.1 carries the fatty acid chain in fatty acid biosynthesis YP_001050099.1 PFAM: beta-ketoacyl synthase; KEGG: son:SO2774 3-oxoacyl-(acyl-carrier-protein) synthase II YP_001050100.1 KEGG: shn:Shewana3_2556 conserved hypothetical protein YP_001050101.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_2462 thioesterase superfamily protein YP_001050102.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: she:Shewmr4_2391 6-phosphogluconate dehydrogenase, NAD-binding YP_001050103.1 PFAM: Aldose 1-epimerase; KEGG: son:SO2769 hypothetical protein YP_001050104.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: shn:Shewana3_2552 acyl-CoA dehydrogenase domain protein YP_001050105.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_3021 integrase, catalytic region YP_001050106.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001050107.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shn:Shewana3_2551 TonB-dependent siderophore receptor YP_001050108.1 PFAM: Patatin; KEGG: shn:Shewana3_2550 patatin YP_001050109.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_001050110.1 PFAM: peptidase M28; KEGG: shn:Shewana3_2548 peptidase M28 YP_001050111.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO2762 nagD protein YP_001050112.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001050113.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001050114.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001050115.1 PFAM: Gluconate transporter; Citrate transporter; Na+/H+ antiporter NhaC; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: shn:Shewana3_2542 Na+/H+ antiporter NhaC YP_001050116.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shn:Shewana3_2541 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_001050117.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_001050118.1 PFAM: OmpA/MotB domain protein; KEGG: shm:Shewmr7_2446 OmpA/MotB domain protein YP_001050119.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller; KEGG: shm:Shewmr7_2445 prolyl oligopeptidase YP_001050120.1 TIGRFAM: 4-hydroxybenzoyl-CoA thioesterase; PFAM: thioesterase superfamily protein; KEGG: shn:Shewana3_2535 4-hydroxybenzoyl-CoA thioesterase YP_001050121.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: shn:Shewana3_2534 MotA/TolQ/ExbB proton channel YP_001050122.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: shn:Shewana3_2533 biopolymer transport protein ExbD/TolR YP_001050123.1 PFAM: TolA family protein; KEGG: shn:Shewana3_2532 TolA family protein YP_001050124.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001050125.1 TIGRFAM: OmpA domain protein; PFAM: OmpA/MotB domain protein; KEGG: shn:Shewana3_2530 OmpA/MotB domain protein YP_001050126.1 PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: shm:Shewmr7_2438 hypothetical protein YP_001050127.1 PFAM: porin; KEGG: shm:Shewmr7_2437 hypothetical protein YP_001050128.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_001050129.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_2435 type III restriction enzyme, res subunit YP_001050130.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001050131.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: shn:Shewana3_2522 putative PAS/PAC sensor protein YP_001050132.1 KEGG: shm:Shewmr7_2016 hypothetical protein YP_001050133.1 TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: son:SO2741 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_001050134.1 KEGG: son:SO2740 biotin synthase; TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_001050135.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; aminotransferase class-III; KEGG: shm:Shewmr7_2430 8-amino-7-oxononanoate synthase YP_001050136.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_2429 biotin biosynthesis protein BioC YP_001050137.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001050138.1 PFAM: histone family protein DNA-binding protein; KEGG: she:Shewmr4_1550 histone family protein DNA-binding protein YP_001050139.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_1627 ABC transporter related YP_001050140.1 KEGG: son:SO1866 hypothetical protein YP_001050141.1 PFAM: protein of unknown function DUF480; KEGG: shn:Shewana3_1622 protein of unknown function DUF480 YP_001050142.1 KEGG: shn:Shewana3_1623 conserved hypothetical protein YP_001050143.1 KEGG: shm:Shewmr7_1631 hypothetical protein YP_001050144.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001050145.1 PFAM: S-adenosylmethionine decarboxylase; KEGG: shn:Shewana3_1625 S-adenosylmethionine decarboxylase YP_001050146.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001050147.1 PFAM: protein of unknown function DUF188; KEGG: shn:Shewana3_1627 protein of unknown function DUF188 YP_001050148.1 PFAM: YceI family protein; KEGG: shn:Shewana3_1628 YceI family protein YP_001050149.1 KEGG: shn:Shewana3_1629 conserved hypothetical protein YP_001050150.1 KEGG: shn:Shewana3_1630 conserved hypothetical protein YP_001050151.1 KEGG: shm:Shewmr7_1640 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein YP_001050152.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_001050153.1 involved in regulation of intracellular pH under alkaline conditions YP_001050154.1 Multifunctional regulator of fatty acid metabolism YP_001050155.1 PFAM: SpoVR family protein; KEGG: shm:Shewmr7_1644 SpoVR family protein YP_001050156.1 PFAM: protein of unknown function DUF444; KEGG: shm:Shewmr7_1645 protein of unknown function DUF444 YP_001050157.1 PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: shm:Shewmr7_1646 putative serine protein kinase, PrkA YP_001050158.1 PFAM: manganese and iron superoxide dismutase; KEGG: shn:Shewana3_1639 manganese and iron superoxide dismutase YP_001050159.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: shn:Shewana3_1640 glutaredoxin-like protein YP_001050160.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: shn:Shewana3_1641 uracil-xanthine permease YP_001050161.1 KEGG: shn:Shewana3_1642 conserved hypothetical protein YP_001050162.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_001050163.1 KEGG: son:SO2876 hypothetical protein YP_001050164.1 KEGG: son:SO2872 hypothetical protein YP_001050165.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: shn:Shewana3_1648 arsenate reductase YP_001050166.1 PFAM: peptidase M48, Ste24p; Tetratricopeptide TPR_2 repeat protein; KEGG: she:Shewmr4_2347 peptidase M48, Ste24p YP_001050167.1 PFAM: SirA family protein; KEGG: shn:Shewana3_1650 SirA family protein YP_001050168.1 PFAM: protein of unknown function UPF0118; KEGG: shn:Shewana3_1651 protein of unknown function UPF0118 YP_001050169.1 KEGG: shn:Shewana3_2511 cytochrome c3 YP_001050170.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: saz:Sama_1445 hypothetical protein YP_001050171.1 PFAM: cytochrome B561; KEGG: shn:Shewana3_2510 cytochrome b561 YP_001050172.1 PFAM: regulatory protein, LuxR; KEGG: shn:Shewana3_2509 transcriptional regulator, LuxR family YP_001050173.1 PFAM: peptidase M61 domain protein; KEGG: she:Shewmr4_2315 peptidase M61 domain protein YP_001050174.1 PFAM: histidine triad (HIT) protein; KEGG: shn:Shewana3_2507 histidine triad (HIT) protein YP_001050175.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_2383 uncharacterized domain 1 YP_001050176.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: shn:Shewana3_2505 thioesterase superfamily protein YP_001050177.1 PFAM: protein of unknown function DUF1425; KEGG: shn:Shewana3_2504 protein of unknown function DUF1425 YP_001050178.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_2310 TonB-dependent receptor YP_001050179.1 KEGG: son:SO2714 hypothetical protein YP_001050180.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: shn:Shewana3_2498 nicotinamide mononucleotide transporter PnuC YP_001050181.1 PFAM: Choline/ethanolamine kinase; aminoglycoside phosphotransferase; KEGG: son:SO2712 hypothetical protein YP_001050182.1 KEGG: son:SO2711 hypothetical protein YP_001050183.1 PFAM: DoxX family protein; KEGG: shn:Shewana3_2495 DoxX family protein YP_001050184.1 PFAM: nitroreductase; KEGG: shm:Shewmr7_2374 nitroreductase YP_001050185.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_2373 GCN5-related N-acetyltransferase YP_001050186.1 SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: shm:Shewmr7_1593 prolyl 4-hydroxylase, alpha subunit YP_001050187.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_1594 GCN5-related N-acetyltransferase YP_001050188.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_1595 GCN5-related N-acetyltransferase YP_001050189.1 KEGG: she:Shewmr4_1529 hypothetical protein YP_001050190.1 KEGG: shm:Shewmr7_1597 hypothetical protein YP_001050191.1 KEGG: son:SO1839 hypothetical protein YP_001050192.1 KEGG: son:SO1840 hypothetical protein YP_001050193.1 KEGG: shn:Shewana3_1593 hypothetical protein YP_001050194.1 KEGG: she:Shewmr4_1533 hypothetical protein YP_001050195.1 PFAM: PKD domain containing protein; Endonuclease/exonuclease/phosphatase; KEGG: son:SO1844 extracellular nuclease, putative YP_001050196.1 KEGG: shn:Shewana3_2432 hypothetical protein YP_001050197.1 KEGG: dps:DP2303 hypothetical protein YP_001050200.1 KEGG: sru:SRU_2817 hypothetical protein YP_001050202.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001050203.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001050204.1 KEGG: shn:Shewana3_1597 conserved hypothetical protein YP_001050205.1 KEGG: she:Shewmr4_1537 hypothetical protein YP_001050206.1 KEGG: son:SO1849 hypothetical protein YP_001050207.1 PFAM: heat shock protein DnaJ domain protein; KEGG: son:SO1850 DnaJ domain protein YP_001050208.1 PFAM: Ppx/GppA phosphatase; KEGG: shn:Shewana3_2418 Ppx/GppA phosphatase YP_001050209.1 PFAM: Polyphosphate kinase; KEGG: she:Shewmr4_2207 polyphosphate kinase YP_001050210.1 KEGG: shn:Shewana3_2416 conserved hypothetical protein YP_001050211.1 PFAM: CreA family protein; KEGG: she:Shewmr4_2205 CreA family protein YP_001050212.1 PFAM: transposase, IS4 family protein; KEGG: shm:Shewmr7_3098 transposase, IS4 family protein YP_001050213.1 catalyzes the formation of L-homocysteine from cystathionine YP_001050214.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: shn:Shewana3_2413 ATP-binding region, ATPase domain protein domain protein YP_001050215.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO2193 DNA-binding response regulator YP_001050216.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein; KEGG: gsu:GSU2471 group II intron, maturase YP_001050217.1 PFAM: OmpA/MotB domain protein; KEGG: shn:Shewana3_2411 OmpA/MotB domain protein YP_001050218.1 PFAM: von Willebrand factor, type A; Vault protein inter-alpha-trypsin domain protein; SMART: Vault protein inter-alpha-trypsin, metazoa; KEGG: shn:Shewana3_2410 vault protein inter-alpha-trypsin domain protein YP_001050219.1 TIGRFAM: sortase family protein; PFAM: peptidase C60, sortase A and B; KEGG: she:Shewmr4_2199 sortase family protein YP_001050220.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: she:Shewmr4_2198 diguanylate cyclase YP_001050221.1 PFAM: peptidase M28; KEGG: she:Shewmr4_2197 peptidase M28 YP_001050222.1 KEGG: shm:Shewmr7_2273 hypothetical protein YP_001050223.1 TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: son:SO2200 ribosomal protein S6 modification protein, putative YP_001050224.1 PFAM: protein of unknown function DUF413; KEGG: son:SO2201 hypothetical protein YP_001050225.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shn:Shewana3_2403 transcriptional regulator, LysR family YP_001050226.1 PFAM: diacylglycerol kinase; KEGG: shn:Shewana3_2402 diacylglycerol kinase YP_001050227.1 catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_001050228.1 PFAM: protein of unknown function DUF450; KEGG: sfr:Sfri_4039 protein of unknown function DUF450 YP_001050229.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: shn:Shewana3_2399 protein tyrosine phosphatase YP_001050230.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_001050231.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: shm:Shewmr7_2262 2OG-Fe(II) oxygenase YP_001050232.1 this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae YP_001050233.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001050234.1 PFAM: peptidase M22, glycoprotease; KEGG: she:Shewmr4_2182 peptidase M22, glycoprotease YP_001050235.1 KEGG: shm:Shewmr7_2258 hypothetical protein YP_001050236.1 KEGG: she:Shewmr4_2180 hypothetical protein YP_001050237.1 KEGG: shm:Shewmr7_2256 hypothetical protein YP_001050238.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: shm:Shewmr7_2255 alpha/beta hydrolase fold YP_001050239.1 Activates fatty acids by binding to coenzyme A YP_001050240.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: she:Shewmr4_2176 ribonuclease D YP_001050241.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001050242.1 TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: shm:Shewmr7_2251 septum site-determining protein MinD YP_001050243.1 blocks the formation of polar Z-ring septums YP_001050244.1 PFAM: protein of unknown function DUF709; KEGG: shm:Shewmr7_2249 protein of unknown function DUF709 YP_001050245.1 TIGRFAM: lytic murein transglycosylase; KEGG: she:Shewmr4_2171 putative transglycosylase YP_001050246.1 PFAM: protein of unknown function UPF0153; KEGG: she:Shewmr4_2170 protein of unknown function UPF0153 YP_001050247.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shn:Shewana3_1862 methyl-accepting chemotaxis sensory transducer YP_001050248.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001050249.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001050250.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001050251.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_001050252.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: pfl:PFL_4865 phenazine biosynthesis protein PhzF family YP_001050253.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: ppu:PP_0648 hypothetical protein YP_001050254.1 TIGRFAM: hydrogenase nickel insertion protein HypA; PFAM: hydrogenase expression/synthesis, HypA; KEGG: shm:Shewmr7_2165 hydrogenase nickel insertion protein HypA YP_001050255.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: she:Shewmr4_1813 hydrogenase expression/formation protein HypE YP_001050256.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: son:SO2091 hydrogenase expression/formation protein HypD YP_001050257.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: son:SO2092 hydrogenase assembly chaperone hypC/hupF YP_001050258.1 TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K; KEGG: son:SO2093 hydrogenase accessory protein HypB YP_001050259.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC, N-terminal domain; zinc finger, HypF domain protein; KEGG: shn:Shewana3_1875 (NiFe) hydrogenase maturation protein HypF YP_001050260.1 KEGG: son:SO2095 hypothetical protein YP_001050261.1 TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52, hydrogen uptake protein; KEGG: shn:Shewana3_1877 hydrogenase expression/formation protein YP_001050262.1 TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: shn:Shewana3_1878 Ni/Fe-hydrogenase, b-type cytochrome subunit YP_001050263.1 PFAM: nickel-dependent hydrogenase, large subunit; KEGG: son:SO2098 hydrogenase large chain YP_001050264.1 KEGG: son:SO2099 hydrogenase small chain; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Nickel-iron dehydrogenase small subunit, N-terminal domain protein YP_001050265.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; Thioredoxin domain; KEGG: shm:Shewmr7_2154 redoxin domain protein YP_001050266.1 KEGG: shn:Shewana3_1882 lipoprotein, putative YP_001050267.1 KEGG: she:Shewmr4_1825 hypothetical protein YP_001050268.1 PFAM: ApbE family lipoprotein; KEGG: she:Shewmr4_1826 ApbE family lipoprotein YP_001050269.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_2150 two component transcriptional regulator, winged helix family YP_001050270.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO2105 sensor protein YgiY, putative YP_001050271.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_001050272.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_001050273.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: she:Shewmr4_1831 peptidoglycan-binding domain 1 protein YP_001050274.1 PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: shn:Shewana3_1890 protein of unknown function DUF882 YP_001050275.1 KEGG: she:Shewmr4_1833 hypothetical protein YP_001050276.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001050277.1 PFAM: protein of unknown function DUF490; KEGG: she:Shewmr4_1835 protein of unknown function DUF490 YP_001050278.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: son:SO2114 hypothetical protein YP_001050279.1 PFAM: peptidase T2, asparaginase 2; KEGG: shm:Shewmr7_2140 peptidase T2, asparaginase 2 YP_001050280.1 KEGG: hch:HCH_03663 predicted membrane protein YP_001050281.1 PFAM: CBS domain containing protein; KEGG: shm:Shewmr7_2139 putative signal transduction protein with CBS domains YP_001050282.1 KEGG: shn:Shewana3_1897 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD-like helicases-like YP_001050283.1 PFAM: periplasmic nitrate reductase NapE; KEGG: shm:Shewmr7_2137 periplasmic nitrate reductase NapE YP_001050284.1 PFAM: NapD family protein; KEGG: shn:Shewana3_1899 NapD family protein YP_001050285.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001050286.1 PFAM: Nitrate reductase cytochrome c-type subunit (NapB); KEGG: shn:Shewana3_1901 nitrate reductase cytochrome c-type subunit (NapB) YP_001050287.1 TIGRFAM: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family; PFAM: NapC/NirT cytochrome c domain protein; KEGG: shn:Shewana3_1902 periplasmic nitrate (or nitrite) reductase C-type cytochrome, NapC/NirT family YP_001050288.1 KEGG: cph:Cpha266_1691 conserved hypothetical protein YP_001050289.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001050290.1 KEGG: shm:Shewmr7_2203 hypothetical protein YP_001050291.1 PFAM: NUDIX hydrolase; KEGG: shm:Shewmr7_2202 NUDIX hydrolase YP_001050292.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein; KEGG: son:SO2221 para-aminobenzoate synthase, component I YP_001050293.1 TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; Fe-S type hydro-lyases tartrate/fumarate beta region; KEGG: son:SO2222 fumarate hydratase, class I, anaerobic, putative YP_001050294.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: shn:Shewana3_2301 peptidase S9, prolyl oligopeptidase active site domain protein YP_001050295.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_2300 GCN5-related N-acetyltransferase YP_001050296.1 KEGG: she:Shewmr4_2121 hypothetical protein YP_001050297.1 PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: she:Shewmr4_1683 iron-containing alcohol dehydrogenase YP_001050298.1 PFAM: multiple antibiotic resistance (MarC)-related proteins; KEGG: son:SO2137 multiple antibiotic resistance protein YP_001050299.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_1685 methyl-accepting chemotaxis sensory transducer YP_001050300.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001050301.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001050302.1 PFAM: phage integrase family protein; KEGG: vpa:VP2136 putative pore-forming cytotoxin integrase YP_001050303.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_3021 integrase, catalytic region YP_001050304.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001050305.1 KEGG: csa:Csal_1356 phage integrase YP_001050306.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001050307.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001050308.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfr:Sfri_4014 transposase IS3/IS911 family protein YP_001050309.1 PFAM: Integrase, catalytic region; KEGG: sfr:Sfri_4013 integrase, catalytic region YP_001050310.1 PFAM: regulatory protein GntR, HTH; KEGG: cvi:CV1900 probable transcriptional regulator YP_001050311.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: plu:plu2271 hypothetical protein YP_001050312.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: mfa:Mfla_2576 protein of unknown function DUF6, transmembrane YP_001050313.1 PFAM: regulatory protein, MerR; KEGG: bam:Bamb_6119 transcriptional regulator, MerR family YP_001050314.1 KEGG: aeh:Mlg_2336 hypothetical protein YP_001050315.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001050316.1 PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: cvi:CV2599 probable two-component response regulator, LuxR family YP_001050317.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: ypn:YPN_3413 two-component sensor/regulator YP_001050319.1 TIGRFAM: type III secretion outer membrane pore, YscC/HrcC family; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: ypn:YPN_3412 type III secretion protein YP_001050320.1 TIGRFAM: type III secretion apparatus protein, YscD/HrpQ family; KEGG: cvi:CV2596 probable type-III secretion protein YP_001050321.1 KEGG: cvi:CV2581 hypothetical protein YP_001050322.1 PFAM: EspA family secreted protein; KEGG: sec:SC1419 secretion system effector SseB YP_001050323.1 PFAM: EspA family secreted protein; KEGG: cvi:CV2582 probable secreted protein EspA YP_001050324.1 TIGRFAM: type III secretion low calcium response chaperone LcrH/SycD; KEGG: cvi:CV2578 type III secretion system CesD protein YP_001050325.1 KEGG: cvi:CV2577 secretion system effector YP_001050326.1 KEGG: spt:SPA1452 putative pathogenicity island effector protein YP_001050327.1 KEGG: cvi:CV2574 secretion system effector SseE YP_001050328.1 KEGG: sgl:SG0475 hypothetical protein YP_001050329.1 TIGRFAM: type III secretion low calcium response chaperone LcrH/SycD; KEGG: spt:SPA1450 putative pathogenicity island protein YP_001050330.1 KEGG: stm:STM1404 secreted effector protein YP_001050331.1 SMART: helix-turn-helix- domain containing protein, AraC type; KEGG: yps:YPTB0315 putative AraC-family regulatory protein YP_001050332.1 TIGRFAM: type III secretion system needle protein; KEGG: cvi:CV2585 secretion system apparatus YP_001050333.1 TIGRFAM: type III secretion system protein, SsaH family; KEGG: sgl:SG1293 putative type III secretion apparatus YP_001050334.1 TIGRFAM: type III secretion apparatus protein, YscI/HrpB family YP_001050335.1 TIGRFAM: type III secretion apparatus lipoprotein, YscJ/HrcJ family; PFAM: secretory protein YscJ/FliF family protein; KEGG: cvi:CV2588 type III secretion system apparatus lipoprotein YP_001050336.1 KEGG: cvi:CV2589 hypothetical protein YP_001050337.1 KEGG: ypn:YPN_3404 type III secretion system apparatus protein YP_001050338.1 TIGRFAM: type III secretion effector delivery regulator, TyeA family; PFAM: SepL/SsaL family protein; KEGG: cvi:CV2590 secretion system apparatus YP_001050339.1 PFAM: Tir chaperone family protein; KEGG: stm:STM2879 secretion chaparone YP_001050340.1 KEGG: bte:BTH_II0849 BopA protein YP_001050341.1 KEGG: sec:SC1434 secretion system apparatus SsaM YP_001050342.1 with SsaC forms part of a protein export system across the inner and outer cell membranes; part of the Salmonella pathogenicity island 2; part of the type III secretion system YP_001050343.1 KEGG: cvi:CV2603 probable type III secretion system ATP synthase; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; SMART: AAA ATPase YP_001050347.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response YP_001050348.1 TIGRFAM: type III secretion protein, HrpO family; PFAM: export protein FliQ, family 3; KEGG: cvi:CV2608 type III secretion apparatus protein EscS YP_001050349.1 TIGRFAM: type III secretion protein SpaR/YscT/HrcT; PFAM: type III secretion system inner membrane R protein; KEGG: cvi:CV2609 type III secretion system EscT protein YP_001050350.1 member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli YP_001050351.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: plu:plu2249 hypothetical protein YP_001050352.1 KEGG: ppu:PP_1659 hypothetical protein YP_001050353.1 KEGG: ppu:PP_1660 hypothetical protein YP_001050354.1 PFAM: glucose-methanol-choline oxidoreductase; FAD dependent oxidoreductase; KEGG: ppu:PP_1661 dehydrogenase subunit, putative YP_001050355.1 KEGG: ftn:FTN_0878 hypothetical protein YP_001050356.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: sfr:Sfri_2502 protein of unknown function DUF6, transmembrane YP_001050357.1 TIGRFAM: isoaspartyl dipeptidase; PFAM: amidohydrolase; KEGG: saz:Sama_2391 isoaspartyl dipeptidase YP_001050358.1 PFAM: C4-dicarboxylate anaerobic carrier; KEGG: saz:Sama_2392 putative S-transferase YP_001050359.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: saz:Sama_2393 TonB-dependent receptor YP_001050360.1 KEGG: saz:Sama_2394 cyanophycinase-related exopeptidase-like protein YP_001050361.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: son:SO2572 peptidyl-prolyl cis-trans isomerase B YP_001050362.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO2571 ATP-dependent RNA helicase, DEAD box family YP_001050363.1 PFAM: protein of unknown function DUF885; KEGG: son:SO2570 lipoprotein, putative YP_001050364.1 KEGG: son:SO2569 hypothetical protein YP_001050365.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001050366.1 PFAM: AsmA family protein; KEGG: shn:Shewana3_2372 AsmA protein YP_001050367.1 KEGG: shm:Shewmr7_2240 intracellular proteinase inhibitor domain protein YP_001050368.1 PFAM: Peptidoglycan-binding LysM; Lytic transglycosylase, catalytic; MLTD_N domain protein; KEGG: shn:Shewana3_2370 MLTD_N domain protein YP_001050369.1 PFAM: beta-lactamase domain protein; KEGG: son:SO2563 metallo-beta-lactamase family protein YP_001050370.1 PFAM: Methyltransferase type 11; KEGG: she:Shewmr4_2160 methyltransferase type 11 YP_001050371.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2236 transcriptional regulator, LysR family YP_001050372.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001050373.1 KEGG: shm:Shewmr7_2234 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_001050374.1 KEGG: shm:Shewmr7_2233 hypothetical protein YP_001050375.1 KEGG: son:SO2875 ISSod10, transposase OrfB YP_001050377.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001050378.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_3021 integrase, catalytic region YP_001050379.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_3021 integrase, catalytic region YP_001050380.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001050381.1 PFAM: transposase, IS4 family protein; KEGG: shm:Shewmr7_3098 transposase, IS4 family protein YP_001050382.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: pfo:Pfl_2176 putative diguanylate cyclase (GGDEF domain) with GAF sensor domain YP_001050383.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: cvi:CV3341 probable sensory transduction protein YP_001050384.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: cvi:CV3340 two-component sensor histidine kinase protein YP_001050385.1 PFAM: phosphate-selective porin O and P; KEGG: sdn:Sden_0638 phosphate-selective porin O and P YP_001050386.1 KEGG: sfr:Sfri_4034 FMN-binding domain protein YP_001050387.1 PFAM: PepSY-associated TM helix domain protein; KEGG: sfr:Sfri_4033 PepSY-associated TM helix domain protein YP_001050388.1 KEGG: vpa:VP1886 hypothetical protein YP_001050389.1 KEGG: psp:PSPPH_A0095 plasmid stabilization system protein, RelE/ParE family YP_001050390.1 KEGG: son:SOA0026 site-specific recombinase, resolvase family YP_001050391.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001050392.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001050393.1 KEGG: shn:Shewana3_1936 thiamine biosynthesis protein ThiC YP_001050394.1 KEGG: shm:Shewmr7_2096 thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1 YP_001050395.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: she:Shewmr4_1883 UBA/ThiF-type NAD/FAD binding protein YP_001050396.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: son:SO2442 thiS protein, putative YP_001050397.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001050398.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_001050399.1 KEGG: shm:Shewmr7_2091 conserved hypothetical methyl-accepting chemotaxis protein YP_001050400.1 KEGG: shn:Shewana3_1943 protein-glutamate O-methyltransferase YP_001050401.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2438 transcriptional regulator, LysR family YP_001050402.1 KEGG: shn:Shewana3_1946 response regulator receiver protein YP_001050403.1 TIGRFAM: alpha-L-glutamate ligase-like protein; KEGG: she:Shewmr4_1892 alpha-L-glutamate ligase-like protein YP_001050404.1 KEGG: shm:Shewmr7_2085 gonadoliberin III-related protein YP_001050405.1 PFAM: protein of unknown function DUF785; KEGG: shn:Shewana3_1949 protein of unknown function DUF785 YP_001050406.1 TIGRFAM: putative methyltransferase; PFAM: methyltransferase, putative; Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_2083 putative methyltransferase YP_001050407.1 TIGRFAM: putative methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shn:Shewana3_1951 putative methyltransferase YP_001050408.1 KEGG: shn:Shewana3_1952 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: extracellular solute-binding protein, family 3 YP_001050409.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001050410.1 PFAM: protein of unknown function DUF28; KEGG: shn:Shewana3_1954 protein of unknown function DUF28 YP_001050411.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001050412.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001050413.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001050414.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001050415.1 PFAM: TonB-dependent receptor, plug; KEGG: shm:Shewmr7_2075 TonB-dependent receptor YP_001050416.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001050417.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001050418.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001050419.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001050420.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO2426 DNA-binding response regulator YP_001050421.1 PFAM: peptidase M14, carboxypeptidase A; KEGG: shn:Shewana3_1960 peptidase M14, carboxypeptidase A YP_001050422.1 KEGG: shn:Shewana3_1961 conserved hypothetical protein YP_001050423.1 PFAM: protein of unknown function DUF1315; KEGG: shm:Shewmr7_2071 protein of unknown function DUF1315 YP_001050424.1 converts asparagine to aspartate and ammonia YP_001050425.1 TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; KEGG: shm:Shewmr7_2069 signal peptide peptidase SppA, 67K type YP_001050426.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_1910 NADH:flavin oxidoreductase/NADH oxidase YP_001050427.1 PFAM: ferredoxin; KEGG: shn:Shewana3_1967 ferredoxin YP_001050428.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_001050429.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001050430.1 KEGG: shn:Shewana3_1970 HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001050431.1 Involved in ubiquinone biosynthesis YP_001050432.1 TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal repeat, beta-propeller; KEGG: she:Shewmr4_1919 DNA gyrase, A subunit YP_001050433.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001050434.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2409 transcriptional regulator, LysR family YP_001050435.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Radical SAM domain protein; KEGG: son:SO2408 radical activating enzyme YP_001050436.1 KEGG: son:SO2407 hypothetical protein YP_001050437.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001050438.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001050439.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001050440.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001050441.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001050442.1 PFAM: protein of unknown function DUF1049; KEGG: shn:Shewana3_1979 protein of unknown function DUF1049 YP_001050443.1 KEGG: son:SO2399 hypothetical protein YP_001050444.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001050445.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: shm:Shewmr7_2049 short-chain dehydrogenase/reductase SDR YP_001050446.1 KEGG: she:Shewmr4_1930 hypothetical protein YP_001050447.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: she:Shewmr4_1931 acyl-CoA dehydrogenase domain protein YP_001050448.1 KEGG: shn:Shewana3_1985 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C YP_001050449.1 KEGG: shn:Shewana3_1986 conserved hypothetical protein YP_001050450.1 KEGG: shn:Shewana3_1987 conserved hypothetical protein YP_001050451.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_001050452.1 PFAM: transposase Tn3 family protein; KEGG: rme:Rmet_6188 transposase Tn3 YP_001050453.1 PFAM: transposase Tn3 family protein; KEGG: ppd:Ppro_3715 transposase Tn3 family protein YP_001050454.1 PFAM: Resolvase, N-terminal domain; Resolvase helix-turn-helix domain protein; KEGG: plu:plu3296 hypothetical protein YP_001050455.1 multidrug efflux protein involved in adaptation to low energy shock YP_001050456.1 PFAM: beta-lactamase; KEGG: shn:Shewana3_1990 beta-lactamase YP_001050457.1 PFAM: DTW domain containing protein; KEGG: son:SO2387 conserved hypothetical protein YP_001050458.1 PFAM: protein of unknown function DUF839; KEGG: shn:Shewana3_1995 protein of unknown function DUF839 YP_001050459.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001050460.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001050461.1 KEGG: shn:Shewana3_1996 phage integrase family protein YP_001050462.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001050463.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001050464.1 KEGG: shn:Shewana3_1997 conserved hypothetical protein YP_001050465.1 KEGG: she:Shewmr4_1945 hypothetical protein YP_001050466.1 KEGG: son:SO2380 RecQ domain protein; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001050467.1 KEGG: vfi:VF0709 hypothetical protein YP_001050468.1 serine protease inhibitor, inhibits trypsin and other proteases YP_001050469.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: shn:Shewana3_2231 cation diffusion facilitator family transporter YP_001050470.1 PFAM: regulatory protein, MarR; KEGG: son:SO2046 transcriptional regulator, MarR family YP_001050471.1 PFAM: sulfatase; protein of unknown function DUF1705; KEGG: she:Shewmr4_2103 sulfatase YP_001050472.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_1872 diguanylate cyclase YP_001050473.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: shm:Shewmr7_1876 CoA-binding domain protein YP_001050474.1 PFAM: chemotaxis sensory transducer; KEGG: son:SO2117 methyl-accepting chemotaxis protein YP_001050475.1 KEGG: son:SO2118 SpoIIAA family protein YP_001050476.1 PFAM: response regulator receiver; KEGG: son:SO2119 response regulator YP_001050477.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001050478.1 PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: son:SO2119 response regulator YP_001050479.1 PFAM: response regulator receiver; KEGG: shm:Shewmr7_1880 response regulator receiver protein YP_001050480.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Hpt domain protein; KEGG: shn:Shewana3_2218 CheA signal transduction histidine kinases YP_001050481.1 PFAM: CheW domain protein; KEGG: shn:Shewana3_2217 CheW protein YP_001050482.1 PFAM: chemotaxis sensory transducer; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: shn:Shewana3_2216 methyl-accepting chemotaxis sensory transducer YP_001050483.1 PFAM: MCP methyltransferase, CheR-type; KEGG: she:Shewmr4_2090 MCP methyltransferase, CheR-type YP_001050484.1 catalyzes the conversion of glutamine residues to glutamate on methyl-accepting chemotaxis receptors YP_001050485.1 PFAM: CheB methylesterase; response regulator receiver; KEGG: shn:Shewana3_2213 response regulator receiver modulated CheB methylesterase YP_001050486.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; Hpt domain protein; KEGG: shn:Shewana3_2212 diguanylate cyclase YP_001050487.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: she:Shewmr4_1722 methyltransferase type 12 YP_001050488.1 SMART: HNH nuclease; KEGG: aha:AHA_1441 hypothetical protein YP_001050489.1 KEGG: sfr:Sfri_3140 hypothetical protein YP_001050490.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO2525 ABC transporter, ATP-binding protein YP_001050491.1 KEGG: sdn:Sden_1749 hypothetical protein YP_001050492.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: she:Shewmr4_2080 transcriptional regulator, AraC family YP_001050493.1 KEGG: shn:Shewana3_2202 putative transcriptional regulator, XRE family YP_001050494.1 PFAM: EAL domain protein; response regulator receiver; KEGG: shn:Shewana3_2201 response regulator receiver modulated diguanylate phosphodiesterase YP_001050496.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: shn:Shewana3_2200 response regulator receiver protein YP_001050497.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sfr:Sfri_0198 diguanylate cyclase YP_001050498.1 KEGG: shm:Shewmr7_1896 hypothetical protein YP_001050499.1 KEGG: shn:Shewana3_2198 conserved hypothetical protein YP_001050500.1 PFAM: PepSY-associated TM helix domain protein; KEGG: she:Shewmr4_2076 PepSY-associated TM helix domain protein YP_001050501.1 KEGG: she:Shewmr4_2075 hypothetical protein YP_001050502.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_0950 TonB-dependent siderophore receptor YP_001050503.1 KEGG: ilo:IL1219 hypothetical protein YP_001050504.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001050505.1 PFAM: CsbD family protein; KEGG: rfr:Rfer_3274 CsbD-like YP_001050506.1 KEGG: rfr:Rfer_1879 hypothetical protein YP_001050507.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001050508.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001050509.1 KEGG: nmu:Nmul_A2196 hypothetical protein YP_001050510.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: she:Shewmr4_1951 MATE efflux family protein YP_001050511.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001050512.1 KEGG: shn:Shewana3_2041 conserved hypothetical protein YP_001050514.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001050515.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001050516.1 PFAM: ribosomal protein L35; KEGG: sfr:Sfri_2026 ribosomal protein L35 YP_001050517.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001050518.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_1959 thioredoxin reductase YP_001050519.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001050520.1 TIGRFAM: alanine dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Shikimate/quinate 5-dehydrogenase; alanine dehydrogenase/PNT domain protein; KEGG: shm:Shewmr7_2015 alanine dehydrogenase YP_001050521.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_001050522.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: shm:Shewmr7_2013 cell divisionFtsK/SpoIIIE YP_001050523.1 PFAM: outer membrane lipoprotein carrier protein LolA; KEGG: shm:Shewmr7_2012 outer membrane lipoprotein carrier protein LolA YP_001050524.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: shn:Shewana3_2052 AAA ATPase, central domain protein YP_001050525.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001050526.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001050527.1 KEGG: shn:Shewana3_2055 conserved hypothetical protein YP_001050528.1 PFAM: DsrC family protein; KEGG: shn:Shewana3_2056 formate dehydrogenase YP_001050529.1 PFAM: DsrH family protein; KEGG: son:SO2378 putative uncharacterized protein involved in oxidation of intracellular sulfur YP_001050530.1 PFAM: DsrE family protein; KEGG: son:SO2377 putative uncharacterized protein involved in oxidation of intracellular sulfur YP_001050531.1 PFAM: DsrE family protein; KEGG: shm:Shewmr7_2004 DsrE family protein YP_001050532.1 PFAM: protein of unknown function UPF0005; KEGG: shn:Shewana3_2060 protein of unknown function UPF0005 YP_001050533.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_1974 transcriptional regulator, LysR family YP_001050534.1 uncharacterized member of the major facilitator superfamily (MFS) YP_001050535.1 KEGG: shn:Shewana3_2063 conserved hypothetical protein YP_001050536.1 PFAM: multi antimicrobial extrusion protein MatE; KEGG: bha:BH2163 hypothetical protein YP_001050537.1 KEGG: shn:Shewana3_2084 permease YP_001050538.1 PFAM: Resolvase, N-terminal domain; Resolvase helix-turn-helix domain protein; KEGG: plu:plu3296 hypothetical protein YP_001050539.1 PFAM: transposase Tn3 family protein; KEGG: neu:NE0835 transposase Tn3 family YP_001050540.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; peptidase C39, bacteriocin processing; SMART: AAA ATPase; KEGG: sdn:Sden_0474 ABC transporter related YP_001050541.1 KEGG: xft:PD1851 endo-1,4-beta-glucanase YP_001050543.1 PFAM: secretion protein HlyD family protein; KEGG: sdn:Sden_0476 secretion protein HlyD YP_001050544.1 PFAM: transposase, IS4 family protein; KEGG: shn:Shewana3_4282 transposase, IS4 family protein YP_001050545.1 PFAM: Resolvase, N-terminal domain; KEGG: son:SOA0026 site-specific recombinase, resolvase family YP_001050546.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001050548.1 PFAM: transposase Tn3 family protein; KEGG: mfa:Mfla_1495 transposase Tn3 YP_001050550.1 KEGG: vfi:VFA0580 hypothetical protein YP_001050554.1 PFAM: Zonular occludens toxin; KEGG: ype:YPO2279 putative phage-related membrane protein YP_001050556.1 KEGG: hdu:HD1452.1 RstR-like phage repressor protein YP_001050557.1 TIGRFAM: phage/plasmid replication protein, gene II/X family; PFAM: phage/plasmid replication protein, gene II/X; KEGG: vch:VC1475 phage replication protein Cri YP_001050560.1 PFAM: Collagen triple helix repeat; KEGG: lme:LEUM_1748 hypothetical protein YP_001050561.1 PFAM: Zonular occludens toxin; KEGG: cps:CPS_0881 zona occludens toxin-like protein YP_001050562.1 PFAM: phage integrase family protein; KEGG: shn:Shewana3_2104 phage integrase family protein YP_001050563.1 KEGG: shm:Shewmr7_1972 hypothetical protein YP_001050564.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: shm:Shewmr7_1971 response regulator receiver modulated metal dependent phosphohydrolase YP_001050565.1 KEGG: shn:Shewana3_2106 conserved hypothetical protein YP_001050566.1 CcoN; FixN YP_001050567.1 CcoO; FixO YP_001050568.1 PFAM: Cbb3-type cytochrome oxidase component; KEGG: shn:Shewana3_2109 Cbb3-type cytochrome oxidase component YP_001050569.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III; PFAM: cytochrome c, class I; KEGG: son:SO2361 cytochrome c oxidase, cbb3-type, subunit III YP_001050570.1 KEGG: shm:Shewmr7_1965 hypothetical protein YP_001050571.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: shn:Shewana3_2112 heavy metal translocating P-type ATPase YP_001050572.1 TIGRFAM: cytochrome oxidase maturation protein, cbb3-type; PFAM: cytochrome oxidase maturation protein cbb3-type; KEGG: son:SO2358 cytochrome oxidase maturation protein, cbb3-type YP_001050573.1 KEGG: son:SO2357 hypothetical protein YP_001050574.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_001050575.1 with UspC and UspD is involved in resistance to UV irradiation YP_001050576.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001050577.1 KEGG: shn:Shewana3_2118 conserved hypothetical protein YP_001050578.1 KEGG: shm:Shewmr7_1957 bax protein, putative YP_001050579.1 PFAM: protein of unknown function UPF0052 and CofD; KEGG: shn:Shewana3_2120 conserved hypothetical protein YP_001050580.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001050581.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent YP_001050582.1 KEGG: she:Shewmr4_2022 hypothetical protein YP_001050583.1 KEGG: son:SO2345 glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001050584.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001050585.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: shm:Shewmr7_1949 catalytic domain of components of various dehydrogenase complexes YP_001050586.1 PFAM: Transketolase, central region; Transketolase domain protein; KEGG: shn:Shewana3_2130 transketolase, central region YP_001050587.1 PFAM: dehydrogenase, E1 component; KEGG: shn:Shewana3_2131 dehydrogenase, E1 component YP_001050588.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_001050589.1 KEGG: shn:Shewana3_2133 peptide methionine sulfoxide reductase; TIGRFAM: peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A YP_001050590.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001050591.1 negative modulator of the initiation of chromosome replication YP_001050592.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: shm:Shewmr7_1942 alpha/beta hydrolase fold YP_001050593.1 KEGG: shn:Shewana3_2137 conserved hypothetical protein YP_001050594.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: shn:Shewana3_2138 CopG domain protein DNA-binding domain protein YP_001050595.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001050596.1 KEGG: shm:Shewmr7_1938 hypothetical protein YP_001050597.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001050598.1 PFAM: glutamine synthetase, catalytic region; KEGG: cvi:CV4298 probable glutamine synthetase YP_001050599.1 PFAM: Na+/H+ antiporter NhaC; KEGG: shm:Shewmr7_1936 Na+/H+ antiporter NhaC YP_001050600.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001050601.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; KEGG: shn:Shewana3_2146 response regulator receiver protein YP_001050602.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_001050603.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001050604.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001050605.1 TIGRFAM: 6-phosphogluconolactonase; KEGG: son:SO2488 6-phosphogluconolactonase YP_001050606.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001050607.1 Represses the expression of the zwf, eda, glp and gap YP_001050608.1 PFAM: pyruvate kinase; KEGG: shn:Shewana3_2153 pyruvate kinase YP_001050609.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001050610.1 PFAM: regulatory protein, TetR; KEGG: shn:Shewana3_2155 transcriptional regulator, TetR family YP_001050611.1 PFAM: peptidase M2, peptidyl-dipeptidase A; KEGG: she:Shewmr4_2051 peptidyl-dipeptidase A YP_001050612.1 PFAM: Smr protein/MutS2; KEGG: she:Shewmr4_2052 Smr protein/MutS2 YP_001050613.1 KEGG: shn:Shewana3_2158 conserved hypothetical protein YP_001050614.1 PFAM: SEC-C motif domain protein; KEGG: she:Shewmr4_2054 sec-C motif domain protein YP_001050615.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: shm:Shewmr7_1920 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) YP_001050616.1 KEGG: shn:Shewana3_2161 conserved hypothetical protein YP_001050617.1 KEGG: shm:Shewmr7_1918 hypothetical protein YP_001050618.1 PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: sdn:Sden_2013 pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001050619.1 KEGG: son:SO2501 radical activating enzyme YP_001050620.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_001050621.1 PFAM: Rhomboid family protein; KEGG: shn:Shewana3_2165 rhomboid family protein YP_001050622.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001050623.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: shm:Shewmr7_1912 diguanylate cyclase/phosphodiesterase YP_001050624.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: shn:Shewana3_2168 electron transport complex, RnfABCDGE type, A subunit YP_001050625.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001050626.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001050627.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_001050628.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_001050629.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_001050630.1 KEGG: shm:Shewmr7_1905 endonuclease III; TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_001050631.1 KEGG: shn:Shewana3_2194 conserved hypothetical protein YP_001050632.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: pae:PA3845 probable transcriptional regulator YP_001050633.1 KEGG: bps:BPSL2082 hypothetical protein YP_001050634.1 KEGG: son:SO2044 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001050635.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001050636.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001050637.1 PFAM: protein of unknown function DUF195; KEGG: son:SO2041 hypothetical protein YP_001050638.1 PFAM: Lytic transglycosylase, catalytic; KEGG: shm:Shewmr7_1863 lytic transglycosylase, catalytic YP_001050639.1 PFAM: EAL domain protein; KEGG: shn:Shewana3_2237 diguanylate phosphodiesterase YP_001050640.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; KEGG: shn:Shewana3_2242 ATPase associated with various cellular activities, AAA_3 YP_001050641.1 PFAM: protein of unknown function DUF58; KEGG: shm:Shewmr7_1855 protein of unknown function DUF58 YP_001050642.1 PFAM: transglutaminase domain protein; KEGG: shn:Shewana3_2244 transglutaminase domain protein YP_001050643.1 TIGRFAM: exodeoxyribonuclease V, gamma subunit; PFAM: Exodeoxyribonuclease V, RecC subunit; KEGG: she:Shewmr4_1775 exodeoxyribonuclease V, gamma subunit YP_001050644.1 TIGRFAM: exodeoxyribonuclease V, beta subunit; PFAM: UvrD/REP helicase; KEGG: shn:Shewana3_2246 exodeoxyribonuclease V, beta subunit YP_001050645.1 TIGRFAM: exodeoxyribonuclease V, alpha subunit; KEGG: shn:Shewana3_2247 exodeoxyribonuclease V, alpha subunit YP_001050646.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1883 acetyltransferase, GNAT family YP_001050647.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: saz:Sama_1668 GGDEF domain-like protein YP_001050648.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001050649.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: she:Shewmr4_2130 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) YP_001050650.1 PFAM: Fmu (Sun) domain protein; KEGG: shm:Shewmr7_2207 Fmu (Sun) domain protein YP_001050651.1 TIGRFAM: glucose/galactose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: shn:Shewana3_2310 glucose/galactose transporter YP_001050652.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: shm:Shewmr7_2209 alpha amylase, catalytic region YP_001050653.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_2134 TonB-dependent receptor YP_001050654.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: shm:Shewmr7_2211 alpha amylase, catalytic region YP_001050655.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: shm:Shewmr7_2212 alpha amylase, catalytic region YP_001050656.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: shm:Shewmr7_2213 glyoxalase/bleomycin resistance protein/dioxygenase YP_001050657.1 KEGG: shm:Shewmr7_2214 hypothetical protein YP_001050658.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: chu:CHU_2249 pyruvate dehydrogenase (pyruvate oxidase) YP_001050659.1 PFAM: FAD dependent oxidoreductase; KEGG: mkm:Mkms_0778 amine oxidase YP_001050660.1 KEGG: bch:Bcen2424_5572 hypothetical protein YP_001050661.1 KEGG: sfr:Sfri_1817 glycine betaine/L-proline ABC transporter, ATPase subunit; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase YP_001050662.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfr:Sfri_1818 binding-protein-dependent transport systems inner membrane component YP_001050663.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine YP_001050664.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: vch:VCA0355 hypothetical protein YP_001050665.1 KEGG: son:SO2529 hypothetical protein YP_001050666.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001050667.1 PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase; KEGG: shm:Shewmr7_2220 methylated-DNA-(protein)-cysteine S-methyltransferase YP_001050668.1 KEGG: son:SO2533 hypothetical protein YP_001050669.1 PFAM: glutamine amidotransferase, class-II; KEGG: son:SO2535 hypothetical amidotransferase YP_001050670.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001050671.1 PFAM: Acetamidase/Formamidase; KEGG: sus:Acid_5428 acetamidase/formamidase YP_001050672.1 PFAM: sodium/hydrogen exchanger; KEGG: shn:Shewana3_2324 sodium/hydrogen exchanger YP_001050673.1 KEGG: shn:Shewana3_2352 hypothetical protein YP_001050674.1 KEGG: shn:Shewana3_2353 hypothetical protein YP_001050675.1 PFAM: phage integrase family protein; KEGG: shn:Shewana3_2354 phage integrase family protein YP_001050676.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: shn:Shewana3_2355 metal dependent phosphohydrolase YP_001050677.1 PFAM: phage integrase family protein; KEGG: shn:Shewana3_2356 phage integrase family protein YP_001050678.1 KEGG: shn:Shewana3_2357 hypothetical protein YP_001050679.1 KEGG: pol:Bpro_0373 transcriptional regulator, Cro/CI family YP_001050680.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein; KEGG: sfr:Sfri_3486 RNA-directed DNA polymerase YP_001050681.1 KEGG: shn:Shewana3_2001 conserved hypothetical protein YP_001050682.1 PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; KEGG: shn:Shewana3_2002 peptidyl-dipeptidase A YP_001050683.1 TIGRFAM: cytidyltransferase-related domain; PFAM: cytidylyltransferase; KEGG: shn:Shewana3_2003 glycerol-3-phosphate cytidylyltransferase YP_001050684.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001050685.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001050686.1 KEGG: shm:Shewmr7_2098 hypothetical protein YP_001050687.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: shn:Shewana3_1934 channel protein, hemolysin III family YP_001050688.1 PFAM: DTW domain containing protein; KEGG: sfr:Sfri_1306 DTW domain containing protein YP_001050689.1 PFAM: NUDIX hydrolase; KEGG: shn:Shewana3_1933 NUDIX hydrolase YP_001050690.1 KEGG: son:SO2449 hypothetical protein YP_001050691.1 KEGG: son:SO2450 alpha-glucosidase YP_001050692.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: shn:Shewana3_1930 transcriptional regulator, AraC family YP_001050693.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: shm:Shewmr7_2104 alkylhydroperoxidase like protein, AhpD family YP_001050694.1 KEGG: shm:Shewmr7_2105 hypothetical protein YP_001050695.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001050696.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001050697.1 PFAM: Forkhead-associated protein; KEGG: sfr:Sfri_2377 FHA domain containing protein YP_001050698.1 PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: sfr:Sfri_2378 serine/threonine protein kinase YP_001050709.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO2458 transporter, putative YP_001050710.1 KEGG: son:SO2459 glucoamylase YP_001050711.1 PFAM: glycoside hydrolase 15-related; KEGG: she:Shewmr4_1869 glucan 1,4-alpha-glucosidase YP_001050712.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: shm:Shewmr7_2110 transcriptional regulator, AraC family YP_001050713.1 PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: shm:Shewmr7_2111 sodium/sulphate symporter YP_001050714.1 PFAM: peptidase S24, S26A and S26B; KEGG: sdy:SDY_1220 UmuD YP_001050715.1 PFAM: UMUC domain protein DNA-repair protein; KEGG: stm:PSLT054 mutagenesis by UV and mutagens; related to umuDC operon YP_001050716.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji, jmjC domain protein; KEGG: cps:CPS_2133 hypothetical protein YP_001050717.1 KEGG: shm:Shewmr7_1848 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_001050718.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: shm:Shewmr7_1847 transcriptional regulator, LacI family YP_001050719.1 KEGG: son:SO2241 hypothetical protein YP_001050720.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: shn:Shewana3_2254 methyl-accepting chemotaxis sensory transducer YP_001050721.1 PFAM: amino acid-binding ACT domain protein; KEGG: shn:Shewana3_2255 conserved hypothetical protein YP_001050722.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: shm:Shewmr7_1843 phosphocarrier, HPr family YP_001050723.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein; KEGG: she:Shewmr4_1764 phosphoenolpyruvate-protein phosphotransferase YP_001050724.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_001050725.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfr:Sfri_0854 major facilitator superfamily MFS_1 YP_001050726.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis protein domain protein; KEGG: vvu:VV2_1623 methyl-accepting chemotaxis protein YP_001050727.1 PFAM: porin, Gram-negative type; KEGG: she:Shewmr4_3663 porin, gram-negative type YP_001050728.1 PFAM: arsenate reductase and related; KEGG: shn:Shewana3_1913 arsenate reductase and related YP_001050729.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001050730.1 PFAM: peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins; KEGG: shn:Shewana3_1911 peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins YP_001050731.1 PFAM: alpha/beta hydrolase fold; KEGG: shm:Shewmr7_2123 alpha/beta hydrolase fold YP_001050732.1 KEGG: saz:Sama_1644 gram negative topoisomerase IV, subunit B YP_001050733.1 KEGG: saz:Sama_1643 conserved hypothetical protein YP_001050734.1 PFAM: carbonic anhydrase; KEGG: shn:Shewana3_1909 carbonic anhydrase YP_001050735.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: shn:Shewana3_1908 DegT/DnrJ/EryC1/StrS aminotransferase YP_001050736.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: she:Shewmr4_1852 iron-containing alcohol dehydrogenase YP_001050737.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001050738.1 KEGG: son:SO2479 hypothetical protein YP_001050739.1 KEGG: shn:Shewana3_2260 hypothetical protein YP_001050740.1 PFAM: Rhodanese domain protein; KEGG: she:Shewmr4_1760 rhodanese domain protein YP_001050741.1 PFAM: glutaredoxin; Glutathione S-transferase, N-terminal domain; KEGG: shn:Shewana3_2262 glutathione S-transferase, C-terminal domain protein YP_001050742.1 KEGG: shm:Shewmr7_1836 hypothetical protein YP_001050743.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: she:Shewmr4_1755 sulphate transporter YP_001050744.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shn:Shewana3_2265 lysine exporter protein (LysE/YggA) YP_001050745.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: shn:Shewana3_2266 transcriptional regulator, GntR family YP_001050746.1 KEGG: she:Shewmr4_1752 alkaline phosphatase YP_001050747.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_1751 drug resistance transporter, Bcr/CflA subfamily YP_001050748.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: shn:Shewana3_2269 acetolactate synthase, large subunit, biosynthetic type YP_001050749.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001050750.1 PFAM: heat shock protein Hsp20; KEGG: son:SO2277 16 kDa heat shock protein A YP_001050751.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001050752.1 PFAM: protein of unknown function DUF528; KEGG: shn:Shewana3_2273 protein of unknown function DUF528 YP_001050753.1 TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: shn:Shewana3_2274 alpha-L-glutamate ligases, RimK family YP_001050754.1 TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: shn:Shewana3_2275 ferredoxin, 2Fe-2S type, ISC system YP_001050755.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_001050756.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_001050757.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; iron-sulfur cluster assembly protein IscA; PFAM: HesB/YadR/YfhF-family protein; KEGG: sdn:Sden_1460 iron-sulfur cluster assembly protein IscA YP_001050758.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: shn:Shewana3_2279 FeS cluster assembly scaffold IscU YP_001050759.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_001050760.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; iron-sulfur cluster assembly transcription factor IscR; PFAM: protein of unknown function UPF0074; KEGG: shn:Shewana3_2281 transcriptional regulator, BadM/Rrf2 family YP_001050761.1 TIGRFAM: serine O-acetyltransferase; KEGG: shn:Shewana3_2282 serine O-acetyltransferase YP_001050762.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: shm:Shewmr7_1816 RNA methyltransferase, TrmH family, group 1 YP_001050763.1 PFAM: inositol monophosphatase; KEGG: shm:Shewmr7_1815 inositol-phosphate phosphatase YP_001050764.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: she:Shewmr4_1734 lipoprotein releasing system, transmembrane protein, LolC/E family YP_001050765.1 KEGG: son:SO2258 lipoprotein releasing system ATP-binding protein LolD; TIGRFAM: lipoprotein releasing system, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase YP_001050766.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: shn:Shewana3_2287 lipoprotein releasing system, transmembrane protein, LolC/E family YP_001050767.1 KEGG: son:SO2256 hypothetical protein YP_001050768.1 KEGG: shm:Shewmr7_1810 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001050769.1 KEGG: she:Shewmr4_1729 hypothetical protein YP_001050770.1 catalyzes the hydrolysis of acylphosphate YP_001050771.1 KEGG: son:SO1425 hypothetical protein YP_001050772.1 KEGG: son:SO1424 hypothetical protein YP_001050773.1 KEGG: tbd:Tbd_0175 hypothetical protein YP_001050774.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein; KEGG: gsu:GSU2471 group II intron, maturase YP_001050775.1 KEGG: tde:TDE1803 hypothetical protein YP_001050776.1 PFAM: protein of unknown function DUF1568; KEGG: shm:Shewmr7_1178 protein of unknown function DUF1568 YP_001050777.1 PFAM: protein of unknown function UPF0227; KEGG: son:SO2251 conserved hypothetical protein YP_001050778.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_001050779.1 KEGG: son:SO2248 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001050780.1 PFAM: putative esterase; KEGG: shm:Shewmr7_2190 carboxylesterase YP_001050781.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: shn:Shewana3_1837 alcohol dehydrogenase, zinc-binding domain protein YP_001050782.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2192 transcriptional regulator, LysR family YP_001050783.1 PFAM: FAD dependent oxidoreductase; KEGG: shn:Shewana3_1835 FAD dependent oxidoreductase YP_001050784.1 PFAM: protein of unknown function DUF938; KEGG: shn:Shewana3_1834 protein of unknown function DUF938 YP_001050785.2 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shn:Shewana3_1861 TonB-dependent receptor YP_001050786.1 SMART: helicase c2; KEGG: shn:Shewana3_1859 helicase C2 YP_001050787.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_001050788.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001050789.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001050790.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_001050791.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001050792.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001050793.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001050794.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_001050795.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter, transmembrane; KEGG: shn:Shewana3_1846 aromatic amino acid transporter YP_001050796.1 KEGG: shn:Shewana3_1845 conserved hypothetical protein YP_001050797.1 KEGG: shm:Shewmr7_2187 hypothetical protein YP_001050798.1 PFAM: Uncharacterised conserved protein UCP025560; KEGG: son:SO2062 hypothetical protein YP_001050799.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_1927 GCN5-related N-acetyltransferase YP_001050800.1 PFAM: protein of unknown function DUF1379; KEGG: she:Shewmr4_1682 protein of unknown function DUF1379 YP_001050801.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001050802.1 PFAM: NAD-glutamate dehydrogenase; KEGG: shm:Shewmr7_1755 NAD-glutamate dehydrogenase YP_001050803.1 KEGG: shm:Shewmr7_1754 hypothetical protein YP_001050804.1 KEGG: shn:Shewana3_1783 BNR repeat protein YP_001050805.1 PFAM: protein of unknown function DUF1329; KEGG: she:Shewmr4_1677 protein of unknown function DUF1329 YP_001050806.1 PFAM: protein of unknown function DUF1302; KEGG: shn:Shewana3_1781 protein of unknown function DUF1302 YP_001050807.1 KEGG: son:SO2598 hypothetical protein YP_001050808.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: shm:Shewmr7_1749 aminopeptidase N YP_001050809.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_001050810.1 affects solute and DNA transport through an unknown mechanism YP_001050811.1 PFAM: GAF domain protein; KEGG: shn:Shewana3_1776 putative GAF sensor protein YP_001050812.1 PFAM: YebG family protein; KEGG: shm:Shewmr7_1745 YebG family protein YP_001050813.1 PFAM: Paraquat-inducible protein A; KEGG: shn:Shewana3_1774 paraquat-inducible protein A YP_001050814.1 PFAM: Paraquat-inducible protein A; KEGG: shn:Shewana3_1773 paraquat-inducible protein A YP_001050815.1 PFAM: Mammalian cell entry related domain protein; KEGG: she:Shewmr4_1667 mammalian cell entry related domain protein YP_001050816.1 PFAM: nucleoside recognition domain protein; KEGG: she:Shewmr4_1666 nucleoside recognition domain protein YP_001050817.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_001050818.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: shm:Shewmr7_1739 hydrolase, TatD family YP_001050819.1 KEGG: shn:Shewana3_1768 type IV pilus biogenesis protein PilZ YP_001050820.1 TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: she:Shewmr4_1662 DNA polymerase III, delta prime subunit YP_001050821.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001050822.1 PFAM: aminodeoxychorismate lyase; KEGG: shm:Shewmr7_1735 aminodeoxychorismate lyase YP_001050823.1 PFAM: aminotransferase, class IV; KEGG: shn:Shewana3_1764 4-amino-4-deoxychorismate lyase YP_001050824.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001050825.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_001050826.1 KEGG: son:SO2618 ATP-binding protein, Mrp/Nbp35 family YP_001050827.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001050828.1 PFAM: Auxin Efflux Carrier; KEGG: she:Shewmr4_1654 auxin efflux carrier YP_001050829.1 PFAM: protein of unknown function DUF34; KEGG: son:SO2621 conserved hypothetical protein TIGR00486 YP_001050830.1 PFAM: 17 kDa surface antigen; KEGG: she:Shewmr4_1652 17 kDa surface antigen YP_001050831.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001050832.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_001050833.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001050834.1 KEGG: shn:Shewana3_1753 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001050835.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001050836.1 KEGG: shn:Shewana3_1751 hypothetical protein; TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001050837.1 KEGG: shn:Shewana3_1750 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type YP_001050838.1 PFAM: pseudouridine synthase; KEGG: shn:Shewana3_1749 pseudouridine synthase, Rsu YP_001050839.1 PFAM: NUDIX hydrolase; KEGG: shn:Shewana3_1748 NUDIX hydrolase YP_001050840.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001050841.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_001050842.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001050843.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji, jmjC domain protein; KEGG: she:Shewmr4_1600 cupin 4 family protein YP_001050844.1 KEGG: son:SO2637 hypothetical protein YP_001050845.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: shn:Shewana3_1742 Glu/Leu/Phe/Val dehydrogenase, dimerisation region YP_001050846.1 KEGG: shm:Shewmr7_1672 hypothetical protein YP_001050847.1 PFAM: regulatory protein, MarR; KEGG: shn:Shewana3_1739 transcriptional regulator, MarR family YP_001050848.1 PFAM: protein of unknown function DUF1285; KEGG: son:SO2642 hypothetical protein YP_001050849.1 PFAM: FAD linked oxidase domain protein; KEGG: she:Shewmr4_1593 FAD linked oxidase domain protein YP_001050850.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001050851.1 PFAM: protein of unknown function DUF299; KEGG: shn:Shewana3_1735 protein of unknown function DUF299 YP_001050852.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_001050853.1 KEGG: sde:Sde_3982 protein of unknown function DUF37; PFAM: glycoside hydrolase, family 18; Carbohydrate-binding family V/XII; chitinase domain protein; SMART: chitinase II YP_001050854.1 PFAM: thioesterase superfamily protein; KEGG: shn:Shewana3_1733 thioesterase superfamily protein YP_001050855.1 PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: son:SO2648 DNA-binding response regulator, LuxR family YP_001050856.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_001050857.1 KEGG: shn:Shewana3_1730 conserved hypothetical protein YP_001050858.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001050859.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_001050860.1 PFAM: Ig domain protein, group 1 domain protein; KEGG: sfr:Sfri_2480 Ig domain protein, group 1 domain protein YP_001050861.1 PFAM: sodium:dicarboxylate symporter; KEGG: shm:Shewmr7_1657 sodium:dicarboxylate symporter YP_001050862.1 KEGG: shn:Shewana3_1725 conserved hypothetical protein YP_001050863.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shn:Shewana3_1724 two component transcriptional regulator, winged helix family YP_001050864.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: shn:Shewana3_1723 ATP-binding region, ATPase domain protein domain protein YP_001050865.1 SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: shn:Shewana3_1722 prolyl 4-hydroxylase, alpha subunit YP_001050866.1 KEGG: shn:Shewana3_1721 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001050867.1 TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2+ transporter protein, CorA family protein; KEGG: shm:Shewmr7_1720 magnesium and cobalt transport protein CorA YP_001050868.1 KEGG: son:SO1940 hypothetical protein YP_001050869.1 KEGG: she:Shewmr4_1643 hypothetical protein YP_001050870.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_001050871.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_001050872.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_1715 GCN5-related N-acetyltransferase YP_001050873.1 PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: shn:Shewana3_1714 GreA/GreB family elongation factor YP_001050874.1 TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: son:SO1933 succinyl-CoA synthetase alpha chain YP_001050875.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001050876.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: shn:Shewana3_1711 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase YP_001050877.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001050878.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001050879.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001050880.1 KEGG: shn:Shewana3_1707 conserved hypothetical succinate dehydrogenase, hydrophobic subunit YP_001050881.1 PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: shn:Shewana3_1706 succinate dehydrogenase, cytochrome b subunit YP_001050882.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001050883.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shn:Shewana3_1704 efflux transporter, RND family, MFP subunit YP_001050884.1 PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_1628 acriflavin resistance protein YP_001050885.1 PFAM: acriflavin resistance protein; KEGG: shn:Shewana3_1702 acriflavin resistance protein YP_001050886.1 PFAM: Uncharacterised conserved protein UCP029143; KEGG: she:Shewmr4_1625 uncharacterized conserved protein UCP029143 YP_001050887.1 KEGG: son:SO1921 hypothetical protein YP_001050888.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; virulence factor MVIN family protein; KEGG: she:Shewmr4_1623 MATE efflux family protein YP_001050889.1 PFAM: Ion transport protein; Ion transport 2 domain protein,; KEGG: shn:Shewana3_2419 ion transport protein YP_001050890.1 KEGG: son:SO2183 hypothetical protein YP_001050891.1 PFAM: protein of unknown function DUF991; KEGG: son:SO2182 hypothetical protein YP_001050892.1 KEGG: son:SO2181 hypothetical protein YP_001050893.1 PFAM: peptidase M23B; KEGG: shn:Shewana3_2423 peptidase M23B YP_001050894.1 KEGG: shn:Shewana3_2424 isocitrate dehydrogenase (NADP(+)) YP_001050895.1 PFAM: Di-haem cytochrome c peroxidase; KEGG: son:SO2178 cytochrome c551 peroxidase YP_001050896.1 PFAM: 37kDa nucleoid-associated protein; KEGG: son:SO2177 hypothetical protein YP_001050897.2 PFAM: protein of unknown function DUF1414; KEGG: shn:Shewana3_2427 protein of unknown function DUF1414 YP_001050898.1 PFAM: sulfatase; KEGG: shn:Shewana3_2428 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase YP_001050899.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: shn:Shewana3_2429 NADH:flavin oxidoreductase/NADH oxidase YP_001050900.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2297 transcriptional regulator, LysR family YP_001050901.1 PFAM: protein of unknown function DUF358; KEGG: ppr:PBPRA1526 hypothetical protein YP_001050902.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_2315 diguanylate cyclase YP_001050903.1 KEGG: shm:Shewmr7_2316 hypothetical protein YP_001050904.1 KEGG: shn:Shewana3_2437 conserved hypothetical protein YP_001050905.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001050906.1 PFAM: PfkB domain protein; KEGG: son:SO2020 inosine-guanosine kinase YP_001050907.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001050908.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001050909.1 PFAM: Thioredoxin domain; KEGG: shn:Shewana3_2442 thioredoxin domain YP_001050910.1 molecular chaperone YP_001050911.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_2409 acriflavin resistance protein YP_001050912.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_2410 efflux transporter, RND family, MFP subunit YP_001050913.1 PFAM: NlpBDapX family lipoprotein; KEGG: she:Shewmr4_2339 NlpBDapX family lipoprotein YP_001050914.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001050915.1 PFAM: amino acid-binding ACT domain protein; KEGG: son:SO1878 glycine cleavage system transcriptional repressor, putative YP_001050916.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_001050917.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shm:Shewmr7_2415 lysine exporter protein (LysE/YggA) YP_001050918.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001050919.1 putative metalloprotease YP_001050920.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_001050921.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_001050922.1 KEGG: she:Shewmr4_1549 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001050923.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001050924.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_001050925.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: pfl:PFL_2312 methyl-accepting chemotaxis transducer YP_001050926.1 KEGG: shn:Shewana3_1607 conserved hypothetical ATP-dependent protease YP_001050927.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001050928.1 PFAM: ribosome modulation factor; KEGG: shn:Shewana3_1605 ribosome modulation factor YP_001050929.1 KEGG: shn:Shewana3_1604 conserved hypothetical protein YP_001050930.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_001050931.1 PFAM: glutaredoxin 2; KEGG: son:SO1852 hypothetical protein YP_001050932.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_001050933.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdn:Sden_3086 GCN5-related N-acetyltransferase YP_001050934.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001050935.1 PFAM: conserved hypothetical protein 103; KEGG: she:Shewmr4_2253 conserved hypothetical protein 103 YP_001050936.1 KEGG: shn:Shewana3_2446 DNA polymerase III, subunits gamma and tau; TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase YP_001050937.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001050938.1 PFAM: protein of unknown function DUF454; KEGG: shn:Shewana3_2448 protein of unknown function DUF454 YP_001050939.1 KEGG: shm:Shewmr7_2329 hypothetical protein YP_001050940.1 KEGG: shn:Shewana3_2449 conserved hypothetical protein YP_001050941.1 PFAM: protein of unknown function DUF692; Xylose isomerase domain protein TIM barrel; KEGG: son:SO2008 hypothetical protein YP_001050942.1 KEGG: she:Shewmr4_2260 hypothetical protein YP_001050943.1 PFAM: dihydrouridine synthase, DuS; KEGG: shn:Shewana3_2452 dihydrouridine synthase, DuS YP_001050944.1 KEGG: shn:Shewana3_2453 transcriptional regulators, TraR/DksA family YP_001050945.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_001050946.1 KEGG: son:SO1999 phospholipase/carboxylesterase family protein YP_001050947.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001050948.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001050949.1 PFAM: phospholipase/Carboxylesterase; KEGG: son:SO1999 phospholipase/carboxylesterase family protein YP_001050950.1 KEGG: shn:Shewana3_2456 conserved hypothetical protein YP_001050951.1 PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: shm:Shewmr7_2339 peptidase M1, membrane alanine aminopeptidase YP_001050952.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: shn:Shewana3_2458 peptidylprolyl isomerase, FKBP-type YP_001050953.1 TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: she:Shewmr4_2269 lytic murein transglycosylase YP_001050954.1 KEGG: shm:Shewmr7_2342 hypothetical protein YP_001050955.1 KEGG: shm:Shewmr7_2343 hypothetical protein YP_001050956.1 PFAM: response regulator receiver; CheW domain protein; KEGG: she:Shewmr4_2272 response regulator receiver modulated CheW protein YP_001050957.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_2345 methyltransferase type 11 YP_001050958.1 PFAM: peptidase S16, lon domain protein; KEGG: she:Shewmr4_2274 peptidase S16, lon domain protein YP_001050959.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: son:SO1986 RNA polymerase sigma-70 factor, ECF subfamily YP_001050960.1 TIGRFAM: anti-sigma factor, putative, ChrR family; KEGG: shm:Shewmr7_2348 anti-ECFsigma factor, ChrR YP_001050961.1 KEGG: shn:Shewana3_2467 conserved hypothetical protein YP_001050962.1 KEGG: shn:Shewana3_2468 conserved hypothetical protein YP_001050963.1 KEGG: son:SO1978 hypothetical protein YP_001050964.1 PFAM: protein of unknown function DUF307; KEGG: shn:Shewana3_2470 protein of unknown function DUF307 YP_001050965.1 PFAM: alpha/beta hydrolase fold; KEGG: she:Shewmr4_2281 alpha/beta hydrolase fold YP_001050966.1 KEGG: shm:Shewmr7_2354 zinc carboxypeptidase-related protein YP_001050967.1 KEGG: shm:Shewmr7_2355 conserved hypothetical ABC transporter protein YP_001050968.1 KEGG: shn:Shewana3_2474 hypothetical protein YP_001050969.1 activates fatty acids by binding to coenzyme A YP_001050970.1 KEGG: son:SO1970 hypothetical protein YP_001050971.1 PFAM: protein of unknown function DUF55; KEGG: shm:Shewmr7_2359 protein of unknown function DUF55 YP_001050972.1 KEGG: shn:Shewana3_2478 conserved hypothetical protein YP_001050973.1 PFAM: transposase, IS4 family protein; KEGG: shm:Shewmr7_3098 transposase, IS4 family protein YP_001050974.1 KEGG: son:SO1967 hypothetical protein YP_001050975.1 PFAM: protein of unknown function DUF124; KEGG: shn:Shewana3_2479 protein of unknown function DUF124 YP_001050976.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO1965 transcriptional regulator, LysR family YP_001050977.1 PFAM: homogentisate 1,2-dioxygenase; KEGG: shm:Shewmr7_2363 homogentisate 1,2-dioxygenase YP_001050978.1 KEGG: son:SO1962 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001050979.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: son:SO1961 maltose O-acetyltransferase YP_001050980.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shm:Shewmr7_2367 lysine exporter protein (LysE/YggA) YP_001050981.1 PFAM: protein of unknown function DUF482; KEGG: she:Shewmr4_2296 protein of unknown function DUF482 YP_001050982.1 KEGG: shn:Shewana3_2487 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_001050983.1 KEGG: dar:Daro_3642 hypothetical protein YP_001050984.1 KEGG: dar:Daro_3643 hypothetical protein YP_001050985.1 KEGG: shn:Shewana3_2491 dipeptidase, putative YP_001050986.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001050987.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001050988.1 KEGG: she:Shewmr4_2301 dipeptidase, putative YP_001050989.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: she:Shewmr4_2302 peptidyl-dipeptidase DCP YP_001050990.1 PFAM: GCN5-related N-acetyltransferase; KEGG: aha:AHA_2408 probable GMP synthase (glutamine-hydrolyzing) YP_001050991.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: shn:Shewana3_1586 peptidase M3A and M3B, thimet/oligopeptidase F YP_001050992.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_001050993.1 KEGG: shn:Shewana3_1584 conserved hypothetical protein YP_001050994.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_001050995.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: she:Shewmr4_1521 transcriptional regulator, GntR family YP_001050996.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis YP_001050997.1 KEGG: she:Shewmr4_1519 hypothetical protein YP_001050998.1 PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: shn:Shewana3_1577 exonuclease, RNase T and DNA polymerase III YP_001050999.1 PFAM: CBS domain containing protein; protein of unknown function DUF294, nucleotidyltransferase putative; KEGG: shn:Shewana3_1576 cyclic nucleotide-binding protein YP_001051000.1 PFAM: Na+/solute symporter; KEGG: shm:Shewmr7_1581 Na+/solute symporter YP_001051001.1 KEGG: son:SO2858 hypothetical protein YP_001051002.1 PFAM: DSBA oxidoreductase; KEGG: shn:Shewana3_1573 DsbA oxidoreductase YP_001051003.1 KEGG: shn:Shewana3_1572 NAD-dependent epimerase/dehydratase YP_001051004.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; KEGG: she:Shewmr4_1510 metal dependent phosphohydrolase YP_001051005.1 KEGG: shn:Shewana3_1570 conserved hypothetical protein YP_001051006.1 KEGG: rru:Rru_A0512 hypothetical protein YP_001051007.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_0238 integrase, catalytic region YP_001051008.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001051009.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001051010.1 KEGG: bca:BCE_0855 DEAD/DEAH box helicase domain protein YP_001051011.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001051012.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_3021 integrase, catalytic region YP_001051013.1 KEGG: bca:BCE_0855 DEAD/DEAH box helicase domain protein YP_001051014.1 KEGG: dps:DP1006 related to NAD-dependent DNA ligase; PFAM: BRCT domain protein; NAD-dependent DNA ligase, OB-fold; NAD-dependent DNA ligase, adenylation; SMART: NAD-dependent DNA ligase-like YP_001051015.1 KEGG: shn:Shewana3_1569 DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase, adenylation; SMART: NAD-dependent DNA ligase-like YP_001051016.1 TIGRFAM: cell division protein ZipA; PFAM: ZipA, C-terminal FtsZ-binding region; KEGG: she:Shewmr4_1507 cell division protein ZipA YP_001051017.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; KEGG: shn:Shewana3_1567 chromosome segregation protein SMC YP_001051018.1 putative role in sulfur assimilation YP_001051019.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001051020.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_3021 integrase, catalytic region YP_001051021.1 PFAM: RDD domain containing protein; KEGG: she:Shewmr4_1501 RDD domain containing protein YP_001051022.1 TIGRFAM: cysteine synthases; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: shn:Shewana3_1561 cysteine synthase A YP_001051023.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: son:SO2906 hypothetical protein YP_001051024.1 KEGG: shn:Shewana3_1558 TonB-dependent receptor YP_001051025.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001051026.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001051027.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sdn:Sden_2404 TonB-dependent receptor YP_001051028.1 PFAM: formate/nitrite transporter; KEGG: shn:Shewana3_1556 methionine gamma-lyase YP_001051029.1 KEGG: son:SO2912 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL YP_001051030.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_001051031.1 PFAM: protein of unknown function DUF412; KEGG: shn:Shewana3_1553 protein of unknown function DUF412 YP_001051032.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001051033.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001051034.1 KEGG: shn:Shewana3_1548 conserved hypothetical protein YP_001051035.1 KEGG: shn:Shewana3_1547 conserved hypothetical protein YP_001051036.1 KEGG: shn:Shewana3_1546 conserved hypothetical protein YP_001051037.1 KEGG: shm:Shewmr7_1551 conserved hypothetical protein 95 YP_001051038.1 PFAM: protein of unknown function UPF0118; KEGG: shm:Shewmr7_1550 protein of unknown function UPF0118 YP_001051039.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_001051040.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; domain of unknown function DUF1731; KEGG: shm:Shewmr7_1548 hypothetical protein YP_001051041.1 PFAM: sodium/glutamate symporter; KEGG: shm:Shewmr7_1547 sodium/glutamate symporter YP_001051042.1 KEGG: son:SO2924 signal peptidase I family protein; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B YP_001051043.1 PFAM: protein of unknown function DUF214; KEGG: son:SO2926 ABC transporter, permease, putative YP_001051044.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shn:Shewana3_1538 ABC transporter related YP_001051045.1 PFAM: lipolytic enzyme, G-D-S-L family; KEGG: shn:Shewana3_1537 lipolytic enzyme, G-D-S-L family YP_001051046.1 KEGG: shn:Shewana3_1536 conserved hypothetical protein YP_001051047.1 PFAM: virulence factor family protein; KEGG: shn:Shewana3_1535 type IV secretory pathway VirJ component-like protein YP_001051048.1 PFAM: protein of unknown function DUF470; protein of unknown function DUF471; protein of unknown function DUF472; KEGG: shn:Shewana3_1534 protein of unknown function DUF470 YP_001051049.1 SohB; periplasmic protein; member of the peptidase S49 family YP_001051050.1 KEGG: she:Shewmr4_1469 hypothetical protein YP_001051051.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_1534 short-chain dehydrogenase/reductase SDR YP_001051052.1 KEGG: son:SO2936 hypothetical protein YP_001051053.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: shm:Shewmr7_1533 pseudouridine synthase, Rsu YP_001051054.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB; KEGG: shn:Shewana3_1524 putative transcriptional regulator YP_001051055.1 PFAM: chromosome segregation and condensation protein ScpA; KEGG: son:SO3015 putative segregation and condensation protein A YP_001051056.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: son:SO3016 Sua5/YciO/YrdC/YwlC family protein YP_001051057.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; KEGG: shn:Shewana3_1521 PHP C-terminal domain protein YP_001051058.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001051059.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001051060.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001051061.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_001051062.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001051063.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001051064.1 KEGG: shm:Shewmr7_1521 hypothetical protein YP_001051065.1 KEGG: shm:Shewmr7_1520 L-lysine 6-monooxygenase (NADPH) YP_001051066.1 KEGG: son:SO3031 siderophore biosynthesis protein, putative YP_001051067.1 PFAM: IucA/IucC family protein; KEGG: she:Shewmr4_1452 IucA/IucC family protein YP_001051068.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_1517 TonB-dependent siderophore receptor YP_001051069.1 PFAM: ferric iron reductase; KEGG: son:SO3034 ferric iron reductase protein, putative YP_001051070.1 Involved in cell division; probably involved in intracellular septation YP_001051071.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_001051072.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_001051074.1 PFAM: transposase, IS4 family protein; KEGG: shm:Shewmr7_3098 transposase, IS4 family protein YP_001051076.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001051077.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001051078.1 KEGG: bcn:Bcen_5285 hypothetical protein YP_001051079.1 PFAM: cyclic nucleotide-binding; SMART: regulatory protein, Crp; KEGG: bch:Bcen2424_5585 transcriptional regulator, Crp/Fnr family YP_001051081.1 KEGG: sfr:Sfri_2036 uncharacterized conserved coiled coil protein YP_001051082.1 PFAM: DSBA oxidoreductase; KEGG: cps:CPS_1239 DsbA-like thioredoxin domain protein YP_001051083.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_1442 methyl-accepting chemotaxis sensory transducer YP_001051084.1 PFAM: protein of unknown function DUF1097; KEGG: shn:Shewana3_1498 protein of unknown function DUF1097 YP_001051085.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: son:SO3048 isoquinoline 1-oxidoreductase, beta subunit, putative YP_001051086.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: shn:Shewana3_1496 (2Fe-2S)-binding domain protein YP_001051087.1 KEGG: son:SO3050 hypothetical protein YP_001051088.1 PFAM: protein of unknown function DUF182; KEGG: shm:Shewmr7_1502 protein of unknown function DUF182 YP_001051089.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: son:SO3052 methyl-accepting chemotaxis protein YP_001051090.1 PFAM: beta-lactamase domain protein; KEGG: shm:Shewmr7_1500 beta-lactamase domain protein YP_001051091.1 PFAM: alpha/beta hydrolase fold; KEGG: shn:Shewana3_1492 alpha/beta hydrolase fold YP_001051092.1 decatenates replicating daughter chromosomes YP_001051093.1 KEGG: shm:Shewmr7_1497 hypothetical protein YP_001051094.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001051095.1 PFAM: Colicin V production protein; KEGG: shm:Shewmr7_1494 colicin V production protein YP_001051096.1 PFAM: Sporulation domain protein; KEGG: she:Shewmr4_1428 sporulation domain protein YP_001051097.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: she:Shewmr4_1427 FolC bifunctional protein YP_001051098.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001051099.1 KEGG: shm:Shewmr7_1490 hypothetical protein YP_001051100.1 KEGG: son:SO3070 aspartate semialdehyde dehydrogenese; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region YP_001051101.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: she:Shewmr4_1423 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region YP_001051102.1 PFAM: beta-ketoacyl synthase; KEGG: shm:Shewmr7_1487 beta-ketoacyl synthase YP_001051103.1 PFAM: FAD dependent oxidoreductase; KEGG: shn:Shewana3_1474 FAD dependent oxidoreductase YP_001051104.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: shm:Shewmr7_1485 tRNA/rRNA methyltransferase (SpoU) YP_001051105.1 KEGG: shn:Shewana3_1472 conserved hypothetical protein YP_001051106.1 PFAM: ATP-NAD/AcoX kinase; KEGG: son:SO3077 hypothetical protein YP_001051107.1 PFAM: nucleoside:H+ symporter; major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_1482 major facilitator superfamily MFS_1 YP_001051108.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001051109.1 involved in methylation of ribosomal protein L3 YP_001051110.1 PFAM: Smr protein/MutS2; KEGG: son:SO3081 Smr domain protein YP_001051111.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase; KEGG: she:Shewmr4_1413 phosphohistidine phosphatase, SixA YP_001051112.1 PFAM: peptidase M16 domain protein; KEGG: shm:Shewmr7_1477 peptidase M16 domain protein YP_001051113.1 KEGG: shm:Shewmr7_1476 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; Two component regulator three Y domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001051114.1 KEGG: son:SO3085 hypothetical protein YP_001051115.1 KEGG: shm:Shewmr7_1474 hypothetical protein YP_001051116.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_001051117.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_001051118.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; KEGG: shn:Shewana3_1459 ATPase associated with various cellular activities, AAA_3 YP_001051119.1 PFAM: protein of unknown function DUF58; KEGG: shm:Shewmr7_1470 protein of unknown function DUF58 YP_001051120.1 KEGG: son:SO3092 hypothetical protein YP_001051121.1 PFAM: von Willebrand factor, type A; KEGG: she:Shewmr4_1403 von Willebrand factor, type A YP_001051122.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: von Willebrand factor, type A; Tetratricopeptide domain protein; KEGG: shn:Shewana3_1455 tetratricopeptide TPR_2 repeat protein YP_001051123.1 KEGG: shm:Shewmr7_1466 hypothetical protein YP_001051124.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001051125.1 KEGG: shn:Shewana3_1452 conserved hypothetical protein YP_001051126.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: shn:Shewana3_1451 sodium/proline symporter YP_001051127.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: saz:Sama_2178 membrane protein involved in aromatic hydrocarbon degradation YP_001051128.1 KEGG: she:Shewmr4_1396 hypothetical protein YP_001051129.1 PFAM: protein of unknown function DUF541; KEGG: shn:Shewana3_1448 protein of unknown function DUF541 YP_001051130.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_1394 efflux transporter, RND family, MFP subunit YP_001051131.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_1458 acriflavin resistance protein YP_001051132.1 KEGG: shm:Shewmr7_1457 hypothetical protein YP_001051133.1 PFAM: Rhodanese domain protein; KEGG: shn:Shewana3_1444 rhodanese domain protein YP_001051134.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdn:Sden_2619 GCN5-related N-acetyltransferase YP_001051135.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; Proprotein convertase, P; protease-associated PA domain protein; peptidase domain protein; proteinase inhibitor I9, subtilisin propeptide; KEGG: shn:Shewana3_1443 peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001051136.1 PFAM: YaeQ family protein; KEGG: son:SO3107 hypothetical protein YP_001051137.1 TIGRFAM: siroheme synthase; KEGG: shn:Shewana3_1441 siroheme synthase YP_001051138.1 PFAM: Rhodanese domain protein; KEGG: she:Shewmr4_1387 rhodanese domain protein YP_001051139.1 KEGG: shm:Shewmr7_1451 hypothetical protein YP_001051140.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001051141.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001051142.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_001051143.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001051144.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001051145.1 KEGG: son:SO3115 hypothetical protein YP_001051146.1 PFAM: protein of unknown function DUF479; KEGG: shm:Shewmr7_1444 protein of unknown function DUF479 YP_001051147.1 PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_1442 pseudouridylate synthase YP_001051148.1 KEGG: son:SO3119 hypothetical protein YP_001051149.1 PFAM: oxidoreductase domain protein; KEGG: shn:Shewana3_1428 oxidoreductase domain protein YP_001051150.1 PFAM: NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30; KEGG: shn:Shewana3_1427 conserved hypothetical protein YP_001051151.1 involved in the import of serine and threonine coupled with the import of sodium YP_001051152.1 PFAM: response regulator receiver; CheW domain protein; KEGG: shn:Shewana3_1425 response regulator receiver modulated CheW protein YP_001051153.1 KEGG: son:SO3124 tyrosine-specific protein phosphatase, putative YP_001051154.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_1434 DEAD/DEAH box helicase domain protein YP_001051155.1 KEGG: shn:Shewana3_1421 methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase YP_001051156.1 PFAM: helix-turn-helix- domain containing protein, AraC type; HhH-GPD family protein; Ada, metal-binding domain protein; AlkA domain protein; KEGG: son:SO3127 Ada regulatory protein, putative YP_001051157.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: she:Shewmr4_1366 ABC transporter related YP_001051158.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001051159.1 KEGG: shn:Shewana3_1417 conserved hypothetical protein YP_001051160.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001051161.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001051162.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: shn:Shewana3_1415 tripartite ATP-independent periplasmic transporter, DctQ component YP_001051163.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: she:Shewmr4_1361 TRAP dicarboxylate transporter, DctM subunit YP_001051164.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: shn:Shewana3_1413 ATP-binding region, ATPase domain protein domain protein YP_001051165.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_1424 two component, sigma54 specific, transcriptional regulator, fis family YP_001051166.1 PFAM: protein of unknown function DUF606; KEGG: pcr:Pcryo_1329 protein of unknown function DUF606 YP_001051167.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: par:Psyc_0050 probable transcriptional regulator, LysR family YP_001051168.1 PFAM: major facilitator superfamily MFS_1; KEGG: shn:Shewana3_1692 Xaa-His dipeptidase YP_001051169.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shn:Shewana3_1691 transcriptional regulator, LysR family YP_001051170.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; peptidase domain protein; proteinase inhibitor I9, subtilisin propeptide; KEGG: son:SO1915 serine protease, subtilase family YP_001051171.1 KEGG: son:SO1913 hypothetical protein YP_001051172.1 KEGG: shn:Shewana3_1688 acyl-CoA thioesterase II; TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase YP_001051173.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_1693 short-chain dehydrogenase/reductase SDR YP_001051174.1 TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; KEGG: son:SO1910 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_001051175.1 PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B; KEGG: son:SO1909 hypothetical protein YP_001051176.1 PFAM: DoxX family protein; KEGG: shn:Shewana3_1684 hypothetical protein YP_001051177.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shn:Shewana3_1683 transcriptional regulator, LysR family YP_001051178.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001051179.1 PFAM: small multidrug resistance protein; KEGG: shn:Shewana3_1676 small multidrug resistance protein YP_001051180.1 PFAM: AMP-dependent synthetase and ligase; KEGG: shn:Shewana3_1675 AMP-dependent synthetase and ligase YP_001051181.1 PFAM: regulatory protein, MerR; KEGG: shn:Shewana3_1673 transcriptional regulator, MerR family YP_001051182.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: son:SO1897 isovaleryl-CoA dehydrogenase YP_001051183.1 PFAM: carboxyl transferase; KEGG: shn:Shewana3_1671 carboxyl transferase YP_001051184.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: shm:Shewmr7_2396 enoyl-CoA hydratase/isomerase YP_001051185.1 PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: shm:Shewmr7_2397 carbamoyl-phosphate synthase L chain, ATP-binding protein YP_001051186.1 PFAM: pyruvate carboxyltransferase; KEGG: she:Shewmr4_2326 pyruvate carboxyltransferase YP_001051187.1 KEGG: son:SO1892 acetate CoA-transferase, subunit A; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001051188.1 KEGG: shn:Shewana3_1666 3-oxoacid CoA-transferase, B subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001051190.1 PFAM: ThiJ/PfpI domain protein; KEGG: son:SO1887 hypothetical protein YP_001051191.1 KEGG: shm:Shewmr7_2405 hypothetical protein YP_001051192.1 PFAM: protein of unknown function DUF81; KEGG: she:Shewmr4_2333 protein of unknown function DUF81 YP_001051193.1 PFAM: glucose sorbosone dehydrogenase; KEGG: ilo:IL2579 glucose dehydrogenase, putative YP_001051194.1 KEGG: nwi:Nwi_0259 hypothetical protein YP_001051195.1 KEGG: shn:Shewana3_1411 conserved hypothetical protein YP_001051196.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_001051197.1 KEGG: shn:Shewana3_1409 hypothetical protein YP_001051198.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: shm:Shewmr7_1420 peptidyl-dipeptidase DCP YP_001051199.1 PFAM: Na+/H+ antiporter NhaC; KEGG: shm:Shewmr7_1419 Na+/H+ antiporter NhaC YP_001051200.1 PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit; KEGG: shm:Shewmr7_1418 electron transfer flavoprotein, alpha subunit YP_001051201.1 PFAM: electron transfer flavoprotein beta-subunit; KEGG: shn:Shewana3_1405 electron transfer flavoprotein beta-subunit YP_001051202.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: shm:Shewmr7_1416 histone family protein nucleoid-structuring protein H-NS YP_001051203.1 KEGG: shn:Shewana3_1403 amidohydrolase YP_001051204.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001051205.1 PFAM: amidohydrolase; KEGG: shn:Shewana3_1403 amidohydrolase YP_001051206.1 KEGG: shm:Shewmr7_1413 lipoprotein, putative YP_001051207.1 PFAM: protein of unknown function UPF0066; KEGG: she:Shewmr4_1347 protein of unknown function UPF0066 YP_001051208.1 KEGG: shm:Shewmr7_1411 transferase hexapeptide repeat containing protein YP_001051209.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001051210.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: sdn:Sden_0610 helix-turn-helix, AraC type YP_001051211.1 KEGG: hch:HCH_00810 3-methyl-2-oxobutanoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase YP_001051212.1 PFAM: Patatin; KEGG: she:Shewmr4_1344 patatin YP_001051213.1 KEGG: shn:Shewana3_1396 conserved hypothetical protein YP_001051214.1 KEGG: shn:Shewana3_1395 lipoprotein, putative YP_001051215.1 PFAM: protein of unknown function DUF1017; KEGG: shm:Shewmr7_1406 protein of unknown function DUF1017 YP_001051216.1 PFAM: protein of unknown function DUF940, membrane lipoprotein putative; KEGG: son:SO3159 hypothetical protein YP_001051217.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: sdn:Sden_1709 NADH:flavin oxidoreductase/NADH oxidase YP_001051218.1 KEGG: she:Shewmr4_1339 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_001051219.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: shm:Shewmr7_1403 glucose-1-phosphate thymidylyltransferase YP_001051220.1 PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein; KEGG: son:SO3162 sensor histidine kinase YP_001051221.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: sdn:Sden_2546 metal-dependent phosphohydrolase, HD subdomain YP_001051222.1 KEGG: son:SO3163 lipoprotein YP_001051223.1 PFAM: protein of unknown function DUF886; KEGG: son:SO3164 hypothetical protein YP_001051224.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001051225.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001051226.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001051227.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001051228.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: sdn:Sden_2645 polysaccharide biosynthesis protein CapD YP_001051229.1 PFAM: sugar transferase; KEGG: son:SO3172 galactosyl transferase YP_001051230.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: net:Neut_0180 NAD-dependent epimerase/dehydratase YP_001051231.1 PFAM: glycosyl transferase, family 2; KEGG: sfv:SFV_2092 dTDP-rhamnosyl transferase YP_001051232.1 WbbJ; catalyzes the transfer of the O-acetyl moiety to the O antigen; part of the lipopolysaccharide biosynthetic pathway YP_001051233.1 PFAM: glycosyl transferase, family 2; KEGG: ana:alr3073 probable glycosyl transferase YP_001051234.1 PFAM: glycosyl transferase, group 1; KEGG: ssp:SSP0538 putative glycosyltransferase YP_001051235.1 KEGG: bfs:BF3456 putative LPS biosynthesis related polysaccharide polymerase YP_001051236.1 PFAM: glycosyl transferase, family 2; KEGG: bfr:BF0813 probable glycosyltransferase YP_001051237.1 PFAM: polysaccharide biosynthesis protein; KEGG: bca:BCE_5560 polysaccharide biosynthesis protein, putative YP_001051238.1 PFAM: glycosyl transferase, group 1; KEGG: cno:NT01CX_1800 glycosyltransferase YP_001051239.1 KEGG: sfr:Sfri_2827 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_001051240.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: shn:Shewana3_1381 dTDP-4-dehydrorhamnose reductase YP_001051241.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: shn:Shewana3_1380 glucose-1-phosphate thymidylyltransferase YP_001051242.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose YP_001051243.1 PFAM: lipopolysaccharide biosynthesis; KEGG: son:SO3191 chain length determinant protein YP_001051244.1 PFAM: polysaccharide export protein; KEGG: son:SO3193 polysaccharide biosynthesis protein YP_001051245.1 KEGG: shm:Shewmr7_1381 NusG antitermination factor; TIGRFAM: transcriptional activator RfaH; PFAM: transcription antitermination protein NusG; SMART: NGN domain protein YP_001051246.1 TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor, type I/II extracellular region; major facilitator superfamily MFS_1; KEGG: shn:Shewana3_1373 amino acid/peptide transporter YP_001051247.1 PFAM: response regulator receiver; KEGG: shm:Shewmr7_1379 response regulator receiver protein YP_001051248.1 PFAM: VacJ family lipoprotein; KEGG: shn:Shewana3_1371 VacJ family lipoprotein YP_001051249.1 KEGG: shn:Shewana3_1370 conserved hypothetical protein YP_001051250.1 KEGG: shn:Shewana3_1369 FlhB domain protein YP_001051251.1 KEGG: shn:Shewana3_1368 conserved hypothetical protein YP_001051252.1 PFAM: CheW domain protein; KEGG: shn:Shewana3_1367 CheW protein YP_001051253.1 PFAM: CheW domain protein; KEGG: she:Shewmr4_1306 CheW protein YP_001051254.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: son:SO3204 ParA family protein YP_001051255.1 KEGG: shn:Shewana3_1364 conserved hypothetical protein YP_001051256.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001051257.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: she:Shewmr4_1302 CheA signal transduction histidine kinases YP_001051258.1 PFAM: Chemotaxis phosphatase, CheZ; KEGG: shn:Shewana3_1361 chemotaxis phosphatase, CheZ YP_001051259.1 PFAM: response regulator receiver; KEGG: shn:Shewana3_1360 response regulator receiver protein YP_001051260.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001051261.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: shn:Shewana3_1358 cobyrinic acid a,c-diamide synthase YP_001051262.1 positive regulator of class III flagellar genes YP_001051263.1 membrane protein involved in the flagellar export apparatus YP_001051264.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001051265.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001051266.1 TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ, family 3; KEGG: son:SO3217 flagellar biosynthetic protein FliQ YP_001051267.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001051268.1 PFAM: flagellar biosynthesis protein, FliO; KEGG: shn:Shewana3_1351 flagellar biosynthesis protein, FliO YP_001051269.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001051270.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001051271.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_001051272.1 PFAM: flagellar hook-length control protein; KEGG: shm:Shewmr7_1354 flagellar hook-length control protein YP_001051273.1 TIGRFAM: flagellar export protein FliJ; KEGG: shn:Shewana3_1346 flagellar export protein FliJ YP_001051274.1 involved in type III protein export during flagellum assembly YP_001051275.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001051276.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001051277.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001051278.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: shm:Shewmr7_1348 flagellar hook-basal body complex subunit FliE YP_001051279.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: shm:Shewmr7_1347 two component, sigma54 specific, transcriptional regulator, fis family YP_001051280.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; SMART: PAS domain containing protein; KEGG: shn:Shewana3_1339 putative PAS/PAC sensor protein YP_001051281.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; flagellar regulatory FleQ domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shn:Shewana3_1338 sigma54 specific transcriptional regulator, fis family YP_001051282.1 flagellin specific chaperone YP_001051283.1 KEGG: shn:Shewana3_1336 conserved hypothetical protein YP_001051284.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; KEGG: shn:Shewana3_1335 flagellar hook-associated 2 domain protein YP_001051285.1 PFAM: flagellar protein FlaG protein; KEGG: shn:Shewana3_1334 flagellar protein FlaG protein YP_001051286.1 PFAM: flagellin domain protein; KEGG: shn:Shewana3_1332 flagellin domain protein YP_001051287.1 PFAM: flagellin domain protein; KEGG: shn:Shewana3_1332 flagellin domain protein YP_001051288.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes. YP_001051289.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: shn:Shewana3_1330 flagellar hook-associated protein FlgK YP_001051290.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_001051291.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001051292.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001051293.1 makes up the distal portion of the flagellar basal body rod YP_001051294.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_001051295.1 the hook connects flagellar basal body to the flagellar filament YP_001051296.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_001051297.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001051298.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod YP_001051299.1 PFAM: MCP methyltransferase, CheR-type; KEGG: shn:Shewana3_1320 MCP methyltransferase, CheR-type YP_001051300.1 PFAM: response regulator receiver; CheW domain protein; KEGG: son:SO3252 chemotaxis protein CheV YP_001051301.1 required for the assembly of the flagellar basal body P-ring YP_001051302.1 PFAM: Anti-sigma-28 factor, FlgM family protein; KEGG: shm:Shewmr7_1325 anti-sigma-28 factor, FlgM YP_001051303.1 PFAM: FlgN family protein; KEGG: shm:Shewmr7_1324 FlgN family protein YP_001051304.1 PFAM: protein of unknown function DUF400; KEGG: son:SO3256 hypothetical protein YP_001051305.1 KEGG: shn:Shewana3_1314 conserved hypothetical protein YP_001051306.1 KEGG: shm:Shewmr7_1321 hypothetical protein YP_001051307.1 PFAM: protein of unknown function DUF115; KEGG: son:SO3259 hypothetical protein YP_001051308.1 KEGG: son:SO3260 hypothetical protein YP_001051309.1 PFAM: N-acetylneuraminic acid synthase, N-terminal domain; KEGG: son:SO3261 polysaccharide biosynthesis related-protein YP_001051310.1 PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; KEGG: pca:Pcar_1119 biotin carboxylase YP_001051311.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: btl:BALH_3482 3-oxoacyl-[acyl-carrier protein] reductase 1 (3-ketoacyl-acyl carrier protein reductase 1) YP_001051312.1 PFAM: Transketolase, central region; Transketolase domain protein; KEGG: gka:GK2392 1-deoxy-D-xylulose 5-phosphate synthase(1-deoxyxylulose-5-phosphate synthase) YP_001051313.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO3266 hypothetical protein YP_001051314.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO3267 hypothetical protein YP_001051315.1 PFAM: glycoside hydrolase, family 57; KEGG: son:SO3268 alpha amylase domain protein YP_001051316.1 PFAM: acylneuraminate cytidylyltransferase; KEGG: son:SO3269 cytidylyltransferase domain protein YP_001051317.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: son:SO3270 polysaccharide biosynthesis protein YP_001051318.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: son:SO3271 polysaccharide biosynthesis protein YP_001051319.1 PFAM: protein of unknown function DUF115; KEGG: son:SO3273 hypothetical protein YP_001051320.1 KEGG: shm:Shewmr7_1320 hypothetical protein YP_001051321.1 KEGG: shn:Shewana3_1299 conserved hypothetical protein YP_001051322.1 KEGG: she:Shewmr4_1248 hypothetical protein YP_001051323.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_1317 transcriptional regulator, TetR family YP_001051324.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO3278 hypothetical protein YP_001051325.1 PFAM: acriflavin resistance protein; KEGG: shn:Shewana3_1295 acriflavin resistance protein YP_001051326.1 PFAM: protein of unknown function DUF465; KEGG: son:SO3280 hypothetical protein YP_001051327.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shn:Shewana3_1293 methyl-accepting chemotaxis sensory transducer YP_001051328.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: shn:Shewana3_1243 cyd operon protein YbgT YP_001051329.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II; KEGG: son:SO3285 cytochrome bd-I oxidase subunit II YP_001051330.1 PFAM: cytochrome bd ubiquinol oxidase, subunit I; KEGG: shn:Shewana3_1241 cytochrome bd ubiquinol oxidase, subunit I YP_001051331.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001051332.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_001051333.1 PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: son:SO3291 cytidine/deoxycytidylate deaminase family protein YP_001051334.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001051335.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001051336.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001051337.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001051338.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_001051339.1 KEGG: shm:Shewmr7_1301 hypothetical protein YP_001051340.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001051341.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001051342.1 KEGG: son:SO3313 hypothetical protein YP_001051343.1 KEGG: she:Shewmr4_1226 type IV pilus biogenesis/stability protein PilW; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001051344.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001051345.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; KEGG: shn:Shewana3_1225 protein of unknown function DUF21 YP_001051346.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: she:Shewmr4_1223 metallophosphoesterase YP_001051347.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shn:Shewana3_1223 transcriptional regulator, LysR family YP_001051348.1 PFAM: DoxX family protein; KEGG: shn:Shewana3_1222 DoxX family protein YP_001051349.1 PFAM: Pirin domain protein domain protein; Cupin 2, conserved barrel domain protein; KEGG: shm:Shewmr7_1291 pirin domain protein domain protein YP_001051350.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO3323 acetyltransferase, GNAT family YP_001051351.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_1219 GCN5-related N-acetyltransferase YP_001051352.1 KEGG: shn:Shewana3_1218 NrfJ-related protein YP_001051353.1 KEGG: she:Shewmr4_1216 hypothetical protein YP_001051354.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_1215 acetyltransferase, GNAT family YP_001051355.1 KEGG: she:Shewmr4_1214 hypothetical protein YP_001051356.1 KEGG: she:Shewmr4_1213 transcriptional regulator, CopG family YP_001051357.1 PFAM: extracellular solute-binding protein, family 1; KEGG: she:Shewmr4_1212 extracellular solute-binding protein, family 1 YP_001051358.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shn:Shewana3_1212 diguanylate cyclase YP_001051359.1 PFAM: protein of unknown function DUF980; KEGG: shn:Shewana3_1211 protein of unknown function DUF980 YP_001051360.1 KEGG: shn:Shewana3_1210 conserved hypothetical protein YP_001051361.1 PFAM: HDOD; KEGG: she:Shewmr4_1208 putative signal transduction protein YP_001051362.1 PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: son:SO3338 L-allo-threonine aldolase YP_001051363.1 PFAM: OmpA/MotB domain protein; KEGG: son:SO3339 OmpA family protein YP_001051364.1 PFAM: MscS Mechanosensitive ion channel; KEGG: shn:Shewana3_1206 MscS mechanosensitive ion channel YP_001051365.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shm:Shewmr7_1275 redoxin domain protein YP_001051366.1 PFAM: protein of unknown function UPF0126; KEGG: shm:Shewmr7_1274 protein of unknown function UPF0126 YP_001051367.1 KEGG: son:SO3343 hypothetical protein YP_001051368.1 KEGG: shm:Shewmr7_1272 hypothetical protein YP_001051369.1 involved in start site selection during the initiation of translation YP_001051370.1 PFAM: protein of unknown function DUF179; KEGG: shn:Shewana3_1200 protein of unknown function DUF179 YP_001051371.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001051372.1 PFAM: ferrochelatase; KEGG: shn:Shewana3_1198 ferrochelatase YP_001051373.1 PFAM: glutathione peroxidase; KEGG: she:Shewmr4_1196 glutathione peroxidase YP_001051374.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: shn:Shewana3_1196 twitching motility protein YP_001051375.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: son:SO3351 twitching motility protein PilT YP_001051376.1 PFAM: alanine racemase domain protein; KEGG: shm:Shewmr7_1264 protein of unknown function UPF0001 YP_001051377.1 KEGG: shn:Shewana3_1193 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_001051378.1 PFAM: protein of unknown function YGGT; KEGG: shm:Shewmr7_1262 protein of unknown function YGGT YP_001051379.1 PFAM: protein of unknown function DUF167; KEGG: shn:Shewana3_1191 conserved hypothetical protein YP_001051380.1 KEGG: shm:Shewmr7_1260 hypothetical protein YP_001051381.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001051382.1 KEGG: shm:Shewmr7_1258 putative oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001051383.1 PFAM: protein of unknown function DUF885; KEGG: she:Shewmr4_1186 protein of unknown function DUF885 YP_001051384.1 PFAM: transposase, IS4 family protein; KEGG: shm:Shewmr7_3098 transposase, IS4 family protein YP_001051385.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shn:Shewana3_1186 transcriptional regulator, LysR family YP_001051386.1 KEGG: shn:Shewana3_1185 conserved hypothetical protein YP_001051387.1 catalyzes the formation of glutamate from glutamine YP_001051388.1 PFAM: protein of unknown function DUF469; KEGG: son:SO3366 hypothetical protein YP_001051389.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001051390.1 TIGRFAM: A/G-specific adenine glycosylase; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: son:SO3368 A/G-specific adenine glycosylase YP_001051391.1 PFAM: Fe(II) trafficking protein YggX; KEGG: son:SO3369 hypothetical protein YP_001051392.1 PFAM: YceI family protein; KEGG: shn:Shewana3_1179 YceI family protein YP_001051393.1 PFAM: cytochrome B561; KEGG: she:Shewmr4_1177 cytochrome b561 YP_001051394.1 KEGG: shn:Shewana3_1177 hypothetical protein YP_001051395.1 KEGG: shn:Shewana3_1176 conserved hypothetical protein YP_001051396.1 KEGG: shn:Shewana3_1175 conserved hypothetical protein YP_001051397.1 KEGG: son:SO3376 hypothetical protein YP_001051398.1 KEGG: son:SO3377 hypothetical protein YP_001051399.1 KEGG: son:SO3378 hypothetical protein YP_001051400.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO3379 cyclopropane-fatty-acyl-phospholipid synthase YP_001051401.1 PFAM: protein of unknown function DUF1365; KEGG: son:SO3380 hypothetical protein YP_001051402.1 PFAM: amine oxidase; KEGG: shm:Shewmr7_1239 amine oxidase YP_001051403.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: son:SO3382 oxidoreductase, short-chain dehydrogenase/reductase family YP_001051404.1 KEGG: shn:Shewana3_1167 transcriptional regulator-related protein YP_001051405.1 PFAM: DNA photolyase, FAD-binding; DNA photolyase domain protein; KEGG: shn:Shewana3_1166 DNA photolyase, FAD-binding YP_001051406.1 PFAM: regulatory protein, MerR; KEGG: son:SO3385 transcriptional regulator, MerR family YP_001051407.1 PFAM: protein of unknown function DUF523; Protein of unknown function DUF1722; KEGG: shm:Shewmr7_1234 protein of unknown function DUF1722 YP_001051408.1 KEGG: she:Shewmr4_1162 hypothetical protein YP_001051409.1 PFAM: Heavy metal transport/detoxification protein; KEGG: son:SO1407 mercuric transport periplasmic protein MerP, putative YP_001051410.1 KEGG: shm:Shewmr7_2872 mercuric transport protein MerT, putative YP_001051411.1 PFAM: transglutaminase domain protein; KEGG: shm:Shewmr7_2873 twin-arginine translocation pathway signal YP_001051412.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001051413.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001051414.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001051415.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_3021 integrase, catalytic region YP_001051416.1 KEGG: saz:Sama_0621 conserved hypothetical protein YP_001051417.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: saz:Sama_0622 putative methyl-accepting chemotaxis sensory transducer YP_001051418.1 KEGG: she:Shewmr4_2791 putative HAAAP family transport protein YP_001051419.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: shn:Shewana3_2971 putative endoribonuclease L-PSP YP_001051420.1 PFAM: protein of unknown function DUF1063; KEGG: son:SO1403 hypothetical protein YP_001051421.1 PFAM: YheO domain protein; KEGG: shn:Shewana3_2973 YheO domain protein YP_001051422.1 KEGG: son:SO1401 hypothetical protein YP_001051423.1 PFAM: protein of unknown function DUF368; KEGG: she:Shewmr4_2796 protein of unknown function DUF368 YP_001051424.1 KEGG: shn:Shewana3_2976 conserved hypothetical protein YP_001051425.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_001051426.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: aha:AHA_0957 HTH-type transcriptional regulator XapR YP_001051427.1 PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: shn:Shewana3_2977 CMP/dCMP deaminase, zinc-binding YP_001051428.1 PFAM: protein of unknown function DUF405; protein of unknown function DUF418; KEGG: son:SO1396 hypothetical protein YP_001051429.1 PFAM: protein of unknown function DUF1294; KEGG: son:SO1395 membrane protein,putative YP_001051430.1 KEGG: dps:DP0534 hypothetical protein YP_001051431.1 PFAM: short chain fatty acid transporter; KEGG: she:Shewmr4_2803 short chain fatty acid transporter YP_001051432.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO1390 peptidyl-prolyl cis-trans isomerase, FKBP-type YP_001051433.1 KEGG: sdn:Sden_2136 chitinase; PFAM: PKD domain containing protein; glycoside hydrolase, family 18; Carbohydrate-binding family V/XII; Chitinase A N-terminal domain protein; SMART: chitinase II YP_001051434.1 PFAM: ROK family protein; KEGG: son:SO1389 ROK family protein YP_001051435.1 PFAM: creatinase; peptidase M24; KEGG: shn:Shewana3_2986 peptidase M24 YP_001051436.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: son:SO1387 HD domain protein YP_001051437.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; KEGG: shn:Shewana3_2987 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor YP_001051438.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: shn:Shewana3_2988 DEAD/DEAH box helicase domain protein YP_001051439.1 PFAM: amino acid permease-associated region; Amino acid transporter, transmembrane; KEGG: aha:AHA_2806 arginine/ornithine antiporter YP_001051440.1 PFAM: homocysteine S-methyltransferase; KEGG: aha:AHA_2807 homocysteine S-methyltransferase YP_001051441.1 KEGG: sdn:Sden_3555 hypothetical protein YP_001051442.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shn:Shewana3_2991 redoxin domain protein YP_001051443.1 KEGG: shn:Shewana3_2992 conserved hypothetical protein YP_001051444.1 KEGG: shm:Shewmr7_2896 hypothetical protein YP_001051446.1 PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase-like; KEGG: ecj:JW5272 predicted oxidoreductase YP_001051447.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: sfu:Sfum_1079 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001051448.1 KEGG: shn:Shewana3_2675 decaheme cytochrome c YP_001051449.1 PFAM: band 7 protein; KEGG: son:SO1377 hypothetical protein YP_001051450.1 PFAM: protein of unknown function DUF1449; KEGG: shn:Shewana3_2997 protein of unknown function DUF1449 YP_001051451.1 KEGG: she:Shewmr4_2818 hypothetical protein YP_001051452.1 PFAM: peptidase M32, carboxypeptidase Taq metallopeptidase; KEGG: shm:Shewmr7_2902 carboxypeptidase Taq YP_001051453.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1374 acetyltransferase, GNAT family YP_001051454.1 PFAM: protein of unknown function DUF486; KEGG: shn:Shewana3_3001 protein of unknown function DUF486 YP_001051455.1 KEGG: shn:Shewana3_3002 conserved hypothetical protein YP_001051456.1 PFAM: RDD domain containing protein; KEGG: shn:Shewana3_3003 RDD domain containing protein YP_001051457.1 PFAM: permease YjgP/YjgQ family protein; KEGG: she:Shewmr4_2825 permease YjgP/YjgQ family protein YP_001051458.1 PFAM: permease YjgP/YjgQ family protein; KEGG: shn:Shewana3_3005 permease YjgP/YjgQ family protein YP_001051459.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001051460.1 KEGG: sdn:Sden_1829 GGDEF domain; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001051461.1 PFAM: DNA polymerase III chi subunit, HolC; KEGG: shm:Shewmr7_1202 DNA polymerase III chi subunit, HolC YP_001051462.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001051463.1 affects carbohydrate metabolism; has regulatory role in many processes YP_001051464.1 KEGG: son:SO3427 aspartokinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase YP_001051465.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001051466.1 PFAM: regulatory protein RecX; KEGG: shm:Shewmr7_1197 regulatory protein RecX YP_001051467.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001051468.1 This protein performs the mismatch recognition step during the DNA repair process YP_001051469.1 TIGRFAM: RNA polymerase sigma factor RpoS; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70 region 1.2; KEGG: son:SO3432 RNA polymerase sigma-38 factor YP_001051470.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; KEGG: shm:Shewmr7_1193 peptidase M23B YP_001051471.1 KEGG: shm:Shewmr7_1192 protein-L-isoaspartate O-methyltransferase; TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_001051472.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001051473.1 PFAM: tRNA pseudouridine synthase D, TruD; KEGG: shm:Shewmr7_1190 pseudouridylate synthase YP_001051474.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001051475.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001051476.1 PFAM: Septum formation initiator; KEGG: shn:Shewana3_1117 septum formation initiator YP_001051477.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001051478.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001051479.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001051480.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis YP_001051481.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001051482.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_001051483.1 KEGG: cps:CPS_1152 hypothetical protein YP_001051485.1 KEGG: stm:STM3846.s putative reverse transcriptase YP_001051487.1 KEGG: sdn:Sden_2463 hypothetical protein YP_001051488.1 PFAM: protein of unknown function UPF0157; KEGG: sdn:Sden_2758 protein of unknown function UPF0157 YP_001051489.1 KEGG: shm:Shewmr7_3098 transposase, IS4 family protein YP_001051490.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001051491.1 KEGG: pha:PSHAa0412 hypothetical protein YP_001051492.1 KEGG: aeh:Mlg_2336 hypothetical protein YP_001051493.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001051494.1 KEGG: bxe:Bxe_A1786 putative transposase YP_001051495.1 KEGG: shm:Shewmr7_3098 transposase, IS4 family protein YP_001051496.1 KEGG: shn:Shewana3_1111 (p)ppGpp synthetase I, SpoT/RelA; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; RelA/SpoT domain protein YP_001051497.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_001051498.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_001051499.1 PFAM: protein of unknown function DUF416; KEGG: she:Shewmr4_1108 protein of unknown function DUF416 YP_001051500.1 KEGG: son:SO3459 hypothetical protein YP_001051501.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shn:Shewana3_1106 transcriptional regulator, LysR family YP_001051502.1 PFAM: Auxin Efflux Carrier; KEGG: shn:Shewana3_1105 transporter, putative YP_001051503.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: son:SO3462 DNA repair protein RecN YP_001051504.1 PFAM: phosphatidylglycerophosphatase A; KEGG: she:Shewmr4_1102 phosphatidylglycerophosphatase YP_001051505.1 KEGG: shn:Shewana3_1101 thiamine-monophosphate kinase; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein domain protein YP_001051506.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001051507.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001051508.1 PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; KEGG: shm:Shewmr7_1164 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_001051509.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001051510.1 KEGG: son:SO3469 riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase, zinc-binding; bifunctional deaminase-reductase domain protein YP_001051511.1 PFAM: ATP-cone domain protein; KEGG: shn:Shewana3_1095 ribonucleotide reductase regulator NrdR-like protein YP_001051512.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001051513.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001051514.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_1157 transcriptional regulator, LysR family YP_001051515.1 PFAM: beta-lactamase domain protein; KEGG: son:SO3474 metallo-beta-lactamase family protein YP_001051516.1 KEGG: shn:Shewana3_1089 putative protein-disulfide isomerase YP_001051517.1 KEGG: pfl:PFL_0312 hypothetical protein YP_001051518.1 PFAM: metallophosphoesterase; SMART: serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase; KEGG: shn:Shewana3_1086 metallophosphoesterase YP_001051519.1 KEGG: son:SO3481 hypothetical protein YP_001051520.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shn:Shewana3_1084 efflux transporter, RND family, MFP subunit YP_001051521.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_1149 acriflavin resistance protein YP_001051522.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: shn:Shewana3_1082 major facilitator superfamily MFS_1 YP_001051523.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: she:Shewmr4_1081 transcriptional regulator, AraC family YP_001051524.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: hch:HCH_01675 permease of the drug/metabolite transporter (DMT) superfamily YP_001051525.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: aci:ACIAD0160 putative transcriptional regulator (AraC family) YP_001051526.1 PFAM: protein of unknown function DUF88; KEGG: sdn:Sden_0372 protein of unknown function DUF88 YP_001051527.1 PFAM: globin; KEGG: she:Shewmr4_1079 globin YP_001051528.1 KEGG: she:Shewmr4_1078 hypothetical protein YP_001051529.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: she:Shewmr4_1077 diguanylate cyclase/phosphodiesterase YP_001051530.1 KEGG: she:Shewmr4_1076 hypothetical protein YP_001051531.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: shn:Shewana3_1078 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family YP_001051532.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_1073 efflux transporter, RND family, MFP subunit YP_001051533.1 PFAM: regulatory protein, TetR; KEGG: shn:Shewana3_1076 transcriptional regulator, TetR family YP_001051534.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: cps:CPS_0421 transcription regulator, LysR family YP_001051535.1 KEGG: vpa:VP1155 hypothetical protein YP_001051536.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001051537.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001051538.1 PFAM: transmembrane pair domain protein; KEGG: vpa:VP1155 hypothetical protein YP_001051539.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_3021 integrase, catalytic region YP_001051540.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001051541.1 KEGG: shn:Shewana3_1074 extracellular solute-binding protein, family 3 YP_001051542.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shn:Shewana3_1073 transcriptional regulator, LysR family YP_001051543.1 PFAM: adenylosuccinate synthetase; KEGG: shm:Shewmr7_1140 adenylosuccinate synthase YP_001051544.1 PFAM: response regulator receiver; CheW domain protein; KEGG: aha:AHA_3838 chemotaxis protein CheV YP_001051545.1 PFAM: thioesterase superfamily protein; KEGG: shn:Shewana3_1071 thioesterase superfamily protein YP_001051546.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: shn:Shewana3_1070 diguanylate cyclase/phosphodiesterase YP_001051547.1 PFAM: HDOD; KEGG: shm:Shewmr7_1137 putative signal transduction protein YP_001051548.1 PFAM: peptidase U32; KEGG: son:SO1252 peptidase, U32 family YP_001051549.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_1135 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001051550.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; peptidase domain protein; proteinase inhibitor I9, subtilisin propeptide; KEGG: sdn:Sden_1016 peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001051551.1 KEGG: shm:Shewmr7_1134 sterol-binding domain protein YP_001051552.1 PFAM: peptidase U32; KEGG: she:Shewmr4_1061 peptidase U32 YP_001051553.1 PFAM: peptidase U32; KEGG: son:SO1248 hypothetical peptidase YP_001051554.1 KEGG: shm:Shewmr7_1131 hypothetical protein YP_001051555.1 PFAM: nucleoside recognition domain protein; KEGG: shn:Shewana3_1062 nucleoside recognition domain protein YP_001051557.1 PFAM: metallophosphoesterase; KEGG: shm:Shewmr7_1122 metallophosphoesterase YP_001051558.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: she:Shewmr4_1056 phospholipid/glycerol acyltransferase YP_001051559.1 PFAM: CBS domain containing protein; KEGG: shm:Shewmr7_1120 CBS domain containing protein YP_001051560.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: son:SO1236 xanthine/uracil permease family protein YP_001051561.1 PFAM: periplasmic nitrate reductase NapE; KEGG: shn:Shewana3_1057 periplasmic nitrate reductase NapE YP_001051562.1 TIGRFAM: trimethylamine-N-oxide reductase c-type cytochrome TorC; PFAM: NapC/NirT cytochrome c domain protein; KEGG: shm:Shewmr7_1117 trimethylamine-N-oxide reductase C-type cytochrome TorC YP_001051563.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor YP_001051564.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; KEGG: she:Shewmr4_1049 multi-sensor hybrid histidine kinase YP_001051565.1 periplasmic sensory protein associated with the TorRS two-component regulatory system YP_001051566.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes YP_001051567.1 PFAM: type IV pilus assembly PilZ; KEGG: shm:Shewmr7_1111 type IV pilus assembly PilZ YP_001051568.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001051569.1 PFAM: type IV pilus assembly PilZ; KEGG: she:Shewmr4_1044 type IV pilus assembly PilZ YP_001051570.1 KEGG: shm:Shewmr7_1108 alpha/beta hydrolase fold YP_001051571.1 KEGG: shn:Shewana3_1046 haloacid dehalogenase domain protein hydrolase; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase YP_001051572.1 KEGG: shn:Shewana3_1045 membrane protein YP_001051573.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_001051574.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_001051575.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_001051576.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001051577.1 PFAM: nucleoside-specific channel-forming protein, Tsx; KEGG: sdn:Sden_1024 nucleoside-specific channel-forming protein, Tsx YP_001051578.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: she:Shewmr4_1035 nucleoside transporter YP_001051579.1 PFAM: TatD-related deoxyribonuclease; KEGG: shn:Shewana3_1038 TatD-related deoxyribonuclease YP_001051580.1 KEGG: saz:Sama_0969 hypothetical protein YP_001051581.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001051582.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_001051583.1 KEGG: son:SO1209 polyribonucleotide nucleotidyltransferase; PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH, type 1, domain protein; SMART: KH domain protein YP_001051584.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: shm:Shewmr7_1095 diguanylate cyclase/phosphodiesterase YP_001051585.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001051586.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001051587.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001051588.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001051589.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001051590.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001051591.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: son:SO1201 preprotein translocase, SecG subunit YP_001051592.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001051593.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001051594.1 KEGG: shn:Shewana3_1024 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase, DHPS YP_001051595.1 KEGG: she:Shewmr4_1019 ATP-dependent metalloprotease FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001051596.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_001051597.1 PFAM: protein of unknown function UPF0044; KEGG: shm:Shewmr7_1082 protein of unknown function UPF0044 YP_001051598.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001051599.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001051600.1 KEGG: shm:Shewmr7_1079 hypothetical protein YP_001051601.1 TIGRFAM: transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: son:SO1191 transcription elongation factor GreA YP_001051602.1 KEGG: shn:Shewana3_1016 conserved hypothetical protein YP_001051603.1 KEGG: son:SO1189 lysozyme YP_001051604.1 PFAM: PepSY-associated TM helix domain protein; KEGG: son:SO1188 hypothetical protein YP_001051605.1 KEGG: she:Shewmr4_1009 hypothetical protein YP_001051606.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001051607.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001051608.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: shn:Shewana3_1010 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family YP_001051609.1 KEGG: shm:Shewmr7_1070 hypothetical protein YP_001051610.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001051611.1 PFAM: PhoH family protein; KEGG: shn:Shewana3_1007 PhoH family protein YP_001051612.1 PFAM: protein of unknown function UPF0054; KEGG: shn:Shewana3_1006 protein of unknown function UPF0054 YP_001051613.1 PFAM: CBS domain containing protein; transporter-associated region; KEGG: shm:Shewmr7_1066 CBS domain containing protein YP_001051614.1 Transfers the fatty acyl group on membrane lipoproteins YP_001051615.1 KEGG: shm:Shewmr7_1064 methylation site containing protein YP_001051616.1 KEGG: sde:Sde_2848 histidine kinase YP_001051617.1 PFAM: protein of unknown function DUF1451; KEGG: shn:Shewana3_1002 protein of unknown function DUF1451 YP_001051618.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001051619.1 PFAM: Rare lipoprotein B; KEGG: shn:Shewana3_1000 rare lipoprotein B YP_001051620.1 KEGG: she:Shewmr4_0995 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta YP_001051621.1 KEGG: shn:Shewana3_0998 nicotinate (nicotinamide) nucleotide adenylyltransferase; TIGRFAM: cytidyltransferase-related domain; nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase YP_001051622.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: shn:Shewana3_0997 iojap-like protein YP_001051623.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001051624.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: shn:Shewana3_0995 penicillin-binding protein, transpeptidase YP_001051625.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: shm:Shewmr7_1055 rod shape-determining protein RodA YP_001051626.1 TIGRFAM: lytic murein transglycosylase B; KEGG: son:SO1166 membrane-bound lytic transglycosylase, putative YP_001051627.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; Sporulation domain protein; KEGG: she:Shewmr4_0988 rare lipoprotein A YP_001051628.1 PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: shm:Shewmr7_1052 serine-type D-Ala-D-Ala carboxypeptidase YP_001051629.1 PFAM: protein of unknown function DUF493; KEGG: son:SO1163 hypothetical protein YP_001051630.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001051631.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001051632.1 TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_1048 ribosomal-protein-alanine acetyltransferase YP_001051633.1 KEGG: shm:Shewmr7_1047 hypothetical protein YP_001051634.1 PFAM: Ferritin, Dps family protein; KEGG: shn:Shewana3_0985 ferritin, Dps family protein YP_001051635.1 PFAM: protein of unknown function DUF1624; KEGG: she:Shewmr4_0980 hypothetical protein YP_001051636.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO1156 TonB-dependent receptor YP_001051637.1 KEGG: shn:Shewana3_0982 conserved hypothetical protein YP_001051638.1 PFAM: SEC-C motif domain protein; KEGG: ppr:PBPRA1441 hypothetical protein YP_001051639.1 KEGG: she:Shewmr4_0977 hypothetical protein YP_001051640.1 PFAM: 3'-5' exonuclease; KEGG: shm:Shewmr7_1014 3'-5' exonuclease YP_001051641.1 PFAM: protein of unknown function DUF808; KEGG: she:Shewmr4_0975 protein of unknown function DUF808 YP_001051642.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001051643.1 SMART: PUA domain containing protein; KEGG: shn:Shewana3_0977 PUA domain containing protein YP_001051644.1 KEGG: shm:Shewmr7_1010 putative lipoprotein YP_001051645.1 PFAM: protein of unknown function DUF692; KEGG: shn:Shewana3_0975 protein of unknown function DUF692 YP_001051646.1 KEGG: shn:Shewana3_0974 conserved hypothetical protein YP_001051647.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: shn:Shewana3_0973 endonuclease/exonuclease/phosphatase YP_001051648.1 KEGG: son:SO1146 hypothetical protein YP_001051649.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: shn:Shewana3_0971 magnesium transporter YP_001051650.1 PFAM: chemotaxis sensory transducer; KEGG: son:SO1144 methyl-accepting chemotaxis protein YP_001051651.1 KEGG: shn:Shewana3_0969 extracellular solute-binding protein, family 3 YP_001051652.1 PFAM: pseudouridine synthase; KEGG: sfr:Sfri_3001 pseudouridine synthase YP_001051653.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001051654.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001051655.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001051656.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: she:Shewmr4_0963 peptidylprolyl isomerase, FKBP-type YP_001051657.1 PFAM: peptidase M48, Ste24p; KEGG: she:Shewmr4_0962 peptidase M48, Ste24p YP_001051658.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_0963 GCN5-related N-acetyltransferase YP_001051659.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_0998 DEAD/DEAH box helicase domain protein YP_001051660.1 KEGG: sfr:Sfri_3652 hypothetical protein YP_001051661.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfr:Sfri_4014 transposase IS3/IS911 family protein YP_001051662.1 PFAM: Integrase, catalytic region; KEGG: sfr:Sfri_4013 integrase, catalytic region YP_001051664.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: vpa:VPA1140 hypothetical protein YP_001051665.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001051666.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001051667.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: she:Shewmr4_0956 protein of unknown function DUF6, transmembrane YP_001051668.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: shm:Shewmr7_0993 YbaK/EbsC protein YP_001051669.1 KEGG: she:Shewmr4_0954 hypothetical protein YP_001051670.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001051671.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001051672.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: shn:Shewana3_0953 xanthine/uracil/vitamin C permease YP_001051673.1 KEGG: son:SO3679 hypothetical protein YP_001051674.1 PFAM: protein of unknown function DUF924; KEGG: shn:Shewana3_3246 protein of unknown function DUF924 YP_001051675.1 SMART: extracellular solute-binding protein, family 3; KEGG: shn:Shewana3_3247 extracellular solute-binding protein, family 3 YP_001051676.1 PFAM: UspA domain protein; KEGG: she:Shewmr4_0875 UspA domain protein YP_001051677.1 PFAM: UspA domain protein; KEGG: shm:Shewmr7_3148 UspA domain protein YP_001051678.1 KEGG: shm:Shewmr7_3149 hypothetical protein YP_001051679.1 PFAM: aldehyde dehydrogenase; KEGG: shm:Shewmr7_3150 aldehyde dehydrogenase YP_001051680.1 PFAM: regulatory protein, TetR; KEGG: she:Shewmr4_0871 transcriptional regulator, TetR family YP_001051681.1 PFAM: Curli production assembly/transport component CsgG; KEGG: shn:Shewana3_3253 curli production assembly/transport component CsgG YP_001051682.1 KEGG: shn:Shewana3_3254 curli production assembly/transport component CsgF, putative YP_001051683.1 KEGG: shn:Shewana3_3255 curli production assembly/transport component CsgE, putative YP_001051684.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: shm:Shewmr7_3155 periplasmic sensor signal transduction histidine kinase YP_001051685.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: shm:Shewmr7_3156 two component, sigma54 specific, transcriptional regulator, fis family YP_001051686.1 PFAM: protein of unknown function DUF214; KEGG: sdn:Sden_2848 protein of unknown function DUF214 YP_001051687.1 PFAM: protein of unknown function DUF214; KEGG: sdn:Sden_2849 protein of unknown function DUF214 YP_001051688.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO3692 ABC transporter, ATP-binding protein YP_001051689.1 KEGG: shm:Shewmr7_3160 hypothetical protein YP_001051690.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: she:Shewmr4_0861 efflux transporter, RND family, MFP subunit YP_001051691.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001051692.1 KEGG: son:SO3696 hypothetical protein YP_001051693.1 KEGG: she:Shewmr4_0858 protein of unknown function DUF1486 YP_001051694.1 KEGG: ana:all3465 unknown protein YP_001051697.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mxa:MXAN_1748 acetyltransferase, GNAT family YP_001051698.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: rxy:Rxyl_0136 transcriptional regulator, GntR family YP_001051699.1 KEGG: son:SO3708 hypothetical protein YP_001051700.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_3270 GCN5-related N-acetyltransferase YP_001051701.1 KEGG: shn:Shewana3_3271 cell division protein ZipA YP_001051702.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_001051703.1 PFAM: aldehyde dehydrogenase; KEGG: ppu:PP_2488 succinic-semialdehyde dehydrogenase, putative YP_001051704.1 PFAM: periplasmic binding protein; KEGG: shn:Shewana3_3272 periplasmic binding protein YP_001051705.1 KEGG: shm:Shewmr7_3175 hypothetical protein YP_001051706.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001051707.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_001051708.1 PFAM: cobalbumin biosynthesis enzyme; KEGG: son:SO1037 cobinamide kinase/cobinamide phosphate guanylyltransferase YP_001051709.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_001051710.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001051711.1 PFAM: transport system permease protein; KEGG: shn:Shewana3_3279 transport system permease protein YP_001051712.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1033 iron-compound ABC transporter, ATP-binding protein, putative YP_001051713.1 PFAM: Phosphoglycerate mutase; KEGG: she:Shewmr4_0839 phosphoglycerate mutase YP_001051714.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_001051715.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: atu:Atu4291 transcriptional regulator, LysR family YP_001051716.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: sus:Acid_4264 short-chain dehydrogenase/reductase SDR YP_001051717.1 KEGG: pen:PSEEN0922 methyl-accepting chemotaxis transducer/sensory box protein; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; SMART: PAC repeat-containing protein YP_001051718.1 KEGG: ter:Tery_4677 hypothetical protein YP_001051719.1 PFAM: protein of unknown function DUF262; KEGG: ter:Tery_4676 hypothetical protein YP_001051720.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: sfr:Sfri_0860 aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding YP_001051721.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: sfr:Sfri_0859 (2Fe-2S)-binding domain protein YP_001051722.1 PFAM: cytochrome c, class I; KEGG: sfr:Sfri_0858 cytochrome c, class I YP_001051723.1 KEGG: shn:Shewana3_2250 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001051724.1 PFAM: dienelactone hydrolase; KEGG: she:Shewmr4_0833 twin-arginine translocation pathway signal YP_001051725.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: vfi:VF1095 transcriptional regulators, LysR family YP_001051726.1 PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: vfi:VF1096 nucleoside permease NupC YP_001051727.1 KEGG: son:SO1004 hypothetical protein YP_001051728.1 KEGG: shn:Shewana3_3288 MORN variant repeat protein YP_001051729.1 PFAM: MORN variant repeat protein; KEGG: shm:Shewmr7_3193 hypothetical protein YP_001051730.1 PFAM: sodium/calcium exchanger membrane region; KEGG: shn:Shewana3_3290 sodium/calcium exchanger membrane region YP_001051731.1 PFAM: Rhomboid family protein; KEGG: she:Shewmr4_0829 rhomboid family protein YP_001051732.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_001051733.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_0887 GCN5-related N-acetyltransferase YP_001051734.1 PFAM: LrgB family protein; KEGG: shm:Shewmr7_0923 LrgB family protein YP_001051735.1 PFAM: LrgA family protein; KEGG: shn:Shewana3_0885 LrgA family protein YP_001051736.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_0921 transcriptional regulator, LysR family YP_001051737.1 KEGG: shn:Shewana3_0883 conserved hypothetical protein YP_001051738.1 PFAM: extracellular solute-binding protein, family 3; KEGG: shm:Shewmr7_0919 extracellular solute-binding protein, family 3 YP_001051739.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO1043 amino acid ABC transporter, permease protein YP_001051740.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shn:Shewana3_0880 ABC transporter related YP_001051741.1 KEGG: vpa:VPA0435 hypothetical protein YP_001051742.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive YP_001051743.1 PFAM: heat shock protein DnaJ domain protein; KEGG: son:SO3716 DnaJ domain protein YP_001051744.1 PFAM: DSBA oxidoreductase; KEGG: shn:Shewana3_0874 DsbA oxidoreductase YP_001051745.1 KEGG: son:SO3719 hypothetical protein YP_001051746.1 KEGG: shn:Shewana3_0871 protoporphyrinogen oxidase YP_001051747.1 PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_3067 major facilitator superfamily MFS_1 YP_001051748.1 KEGG: shm:Shewmr7_0904 hypothetical protein YP_001051749.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; KEGG: shn:Shewana3_0868 response regulator receiver modulated diguanylate cyclase/phosphodiesterase YP_001051750.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: shn:Shewana3_0867 ATP-binding region, ATPase domain protein domain protein YP_001051751.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_001051752.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: shn:Shewana3_0865 TrkA-C domain protein YP_001051753.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_001051754.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001051755.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: shm:Shewmr7_0899 uroporphyrin-III C-methyltransferase YP_001051756.1 PFAM: phospholipase A1; KEGG: shm:Shewmr7_0898 phospholipase A(1) YP_001051757.1 KEGG: she:Shewmr4_3075 hypothetical protein YP_001051758.1 KEGG: shn:Shewana3_0859 conserved hypothetical protein YP_001051759.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_001051760.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_001051761.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_001051762.1 TIGRFAM: sulfite reductase [NADPH] flavoprotein, alpha chain; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; flavodoxin/nitric oxide synthase; KEGG: shn:Shewana3_0855 sulfite reductase (NADPH) flavoprotein, alpha chain YP_001051763.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_001051764.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_001051765.1 KEGG: shm:Shewmr7_0889 hypothetical protein YP_001051766.1 KEGG: saz:Sama_0735 conserved hypothetical protein YP_001051767.1 PFAM: regulatory protein, TetR; KEGG: shn:Shewana3_0851 transcriptional regulator, TetR family YP_001051768.1 KEGG: shm:Shewmr7_0887 hypothetical protein YP_001051769.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_001051770.1 TIGRFAM: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; PFAM: lipid A biosynthesis acyltransferase; KEGG: shm:Shewmr7_0885 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase YP_001051771.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_001051772.1 KEGG: shm:Shewmr7_2016 hypothetical protein YP_001051773.1 PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: son:SO3748 LysM domain protein YP_001051774.1 KEGG: shn:Shewana3_0843 conserved hypothetical protein YP_001051775.1 PFAM: peptidase M16 domain protein; KEGG: shn:Shewana3_0842 peptidase M16 domain protein YP_001051776.1 PFAM: peptidase M16 domain protein; KEGG: she:Shewmr4_3094 peptidase M16 domain protein YP_001051777.1 PFAM: response regulator receiver; KEGG: she:Shewmr4_3095 response regulator receiver and unknown domain protein YP_001051778.1 PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: she:Shewmr4_3096 signal transduction histidine kinase regulating citrate/malate metabolism YP_001051779.1 PFAM: protein of unknown function DUF112, transmembrane; KEGG: she:Shewmr4_3097 protein of unknown function DUF112, transmembrane YP_001051780.1 KEGG: she:Shewmr4_3098 putative tricarboxylic transport membrane protein YP_001051781.1 PFAM: Uncharacterized protein UPF0065; KEGG: shm:Shewmr7_0873 uncharacterized protein UPF0065 YP_001051782.1 PFAM: phosphate-selective porin O and P; KEGG: shm:Shewmr7_0872 phosphate-selective porin O and P YP_001051783.1 KEGG: she:Shewmr4_3101 protein of unknown function DUF583 YP_001051784.1 PFAM: protein of unknown function DUF583; KEGG: shm:Shewmr7_0871 protein of unknown function DUF583 YP_001051785.1 PFAM: AFG1-family ATPase; KEGG: shn:Shewana3_0839 AFG1-family ATPase YP_001051786.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001051787.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: ppu:PP_0317 methyl-accepting chemotaxis transducer YP_001051788.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_0866 transcriptional regulator, LysR family YP_001051789.1 PFAM: protein of unknown function DUF897; KEGG: she:Shewmr4_3107 protein of unknown function DUF897 YP_001051790.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: shm:Shewmr7_0864 diguanylate cyclase with GAF sensor YP_001051791.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001051792.1 KEGG: she:Shewmr4_3110 hypothetical protein YP_001051793.1 PFAM: protein of unknown function DUF350; KEGG: shn:Shewana3_0830 protein of unknown function DUF350 YP_001051794.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001051795.1 KEGG: shn:Shewana3_0828 conserved hypothetical protein YP_001051796.1 PFAM: PspA/IM30 family protein; KEGG: shn:Shewana3_0827 phage shock protein A, PspA YP_001051797.1 KEGG: shn:Shewana3_0826 conserved hypothetical protein YP_001051798.1 KEGG: shm:Shewmr7_0856 hypothetical protein YP_001051799.1 PFAM: Ion transport protein; Ion transport 2 domain protein,; KEGG: shn:Shewana3_0824 ion transport 2 domain protein YP_001051800.1 PFAM: adenylate cyclase; KEGG: she:Shewmr4_3118 adenylate cyclase YP_001051801.1 PFAM: protein of unknown function DUF47; KEGG: shn:Shewana3_0822 protein of unknown function DUF47 YP_001051802.1 PFAM: phosphate transporter; KEGG: she:Shewmr4_3120 phosphate transporter YP_001051803.1 PFAM: SH3, type 3 domain protein; SMART: SH3 domain protein domain protein; KEGG: shn:Shewana3_0820 SH3, type 3 domain protein YP_001051804.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain YP_001051805.1 PFAM: protein of unknown function DUF599; KEGG: shm:Shewmr7_0844 protein of unknown function DUF599 YP_001051806.1 KEGG: shn:Shewana3_0816 DNA binding domain, excisionase family YP_001051807.1 TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: son:SO3778 adenylate cyclase CyaB, putative YP_001051808.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001051809.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001051810.1 KEGG: son:SO3781 hypothetical protein YP_001051811.1 KEGG: shm:Shewmr7_0839 hypothetical protein YP_001051812.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: she:Shewmr4_3129 DEAD/DEAH box helicase domain protein YP_001051813.1 KEGG: lpn:lpg0198 hypothetical protein YP_001051814.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_001051815.1 PFAM: Pirin domain protein domain protein; Pirin domain protein; KEGG: shn:Shewana3_3385 hypoxanthine phosphoribosyltransferase YP_001051816.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein, AraC type; methylated-DNA-[protein]-cysteine S-methyltransferase; KEGG: ilo:IL0070 O6-methylguanine-DNA methyltransferase YP_001051817.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: aha:AHA_1994 glucose 1-dehydrogenase YP_001051818.1 KEGG: shm:Shewmr7_1510 hypothetical protein YP_001051819.1 PFAM: protein of unknown function DUF1568; KEGG: she:Shewmr4_2555 protein of unknown function DUF1568 YP_001051820.1 KEGG: aha:AHA_1994 glucose 1-dehydrogenase YP_001051821.1 KEGG: shn:Shewana3_3392 conserved hypothetical protein YP_001051822.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0885 ABC transporter, ATP-binding protein YP_001051823.1 KEGG: shn:Shewana3_3394 conserved hypothetical protein YP_001051824.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: son:SO0883 hypothetical protein YP_001051825.1 PFAM: helix-turn-helix, HxlR type; KEGG: sfr:Sfri_3601 transcriptional regulator, HxlR family protein YP_001051826.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sfr:Sfri_3600 short-chain dehydrogenase/reductase SDR YP_001051827.1 KEGG: vpa:VPA1309 hypothetical protein YP_001051828.1 PFAM: glucose-methanol-choline oxidoreductase; KEGG: she:Shewmr4_0738 glucose-methanol-choline oxidoreductase YP_001051829.1 KEGG: shn:Shewana3_3397 conserved hypothetical protein YP_001051830.1 KEGG: shm:Shewmr7_3286 alpha/beta hydrolase fold YP_001051831.1 KEGG: she:Shewmr4_0735 protein of unknown function UPF0270 YP_001051832.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: shn:Shewana3_3400 phosphoribulokinase/uridine kinase YP_001051833.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO0877 acetyltransferase, GNAT family YP_001051834.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_001051835.1 Regulatory factor involved in maltose metabolism YP_001051836.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger, DksA/TraR C4-type; KEGG: shm:Shewmr7_3292 transcriptional regulators, TraR/DksA family YP_001051837.1 PFAM: glutamyl-tRNA synthetase, class Ic; KEGG: shn:Shewana3_3405 glutamyl-tRNA synthetase, class Ic YP_001051838.1 TIGRFAM: poly(A) polymerase; PFAM: Polynucleotide adenylyltransferase region; KEGG: shm:Shewmr7_3294 poly(A) polymerase YP_001051839.1 KEGG: son:SO0871 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK YP_001051840.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001051841.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001051842.1 KEGG: she:Shewmr4_1960 hypothetical protein YP_001051843.1 KEGG: shm:Shewmr7_3298 hypothetical protein YP_001051844.1 PFAM: Curlin associated repeat protein; KEGG: shn:Shewana3_3412 curlin associated repeat protein YP_001051845.1 PFAM: Curlin associated repeat protein; KEGG: shn:Shewana3_3413 curlin associated repeat protein YP_001051846.1 PFAM: regulatory protein, LuxR; KEGG: shn:Shewana3_3414 transcriptional regulator, LuxR family YP_001051847.1 KEGG: shm:Shewmr7_3303 hypothetical protein YP_001051848.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001051849.1 PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: shm:Shewmr7_3305 glycine cleavage T protein (aminomethyl transferase) YP_001051850.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: shm:Shewmr7_3306 response regulator receiver modulated metal dependent phosphohydrolase YP_001051851.1 KEGG: shn:Shewana3_3419 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001051852.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: she:Shewmr4_0714 amino acid carrier protein YP_001051853.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_3309 ABC transporter related YP_001051854.1 PFAM: protein of unknown function DUF214; KEGG: she:Shewmr4_0712 protein of unknown function DUF214 YP_001051855.1 KEGG: shn:Shewana3_3423 conserved hypothetical protein YP_001051856.1 PFAM: NapD family protein; KEGG: shn:Shewana3_3429 NapD family protein YP_001051857.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001051858.1 PFAM: Nitrate reductase cytochrome c-type subunit (NapB); KEGG: shm:Shewmr7_3321 nitrate reductase cytochrome c-type subunit (NapB) YP_001051859.1 KEGG: she:Shewmr4_0700 hypothetical protein YP_001051860.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_3323 transcriptional regulator, LysR family YP_001051861.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001051862.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO0841 GGDEF domain protein YP_001051863.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001051864.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001051865.1 SMART: extracellular solute-binding protein, family 3; KEGG: shn:Shewana3_3437 diguanylate cyclase YP_001051866.1 PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: son:SO0840 acetyl-CoA carboxylase multifunctional enzyme accADC, carboxyl transferase subunit alpha/carboxyl transferase subunit beta/biotin carboxylase YP_001051867.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shn:Shewana3_3439 transcriptional regulator, LysR family YP_001051868.1 PFAM: penicillin-binding protein, transpeptidase; KEGG: son:SO0837 beta-lactamase, putative YP_001051869.1 KEGG: she:Shewmr4_0693 hypothetical protein YP_001051870.1 PFAM: protein of unknown function DUF335, SprT; SMART: protein of unknown function SprT; KEGG: shm:Shewmr7_3330 protein of unknown function DUF335, SprT YP_001051871.1 PFAM: Endonuclease I; KEGG: shn:Shewana3_3443 endonuclease I YP_001051872.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001051873.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001051874.1 PFAM: transposase, IS4 family protein; KEGG: shm:Shewmr7_3098 transposase, IS4 family protein YP_001051875.1 PFAM: Alkaline phosphatase; KEGG: shn:Shewana3_3446 alkaline phosphatase YP_001051876.1 PFAM: methyltransferase small; Methyltransferase small, N-terminal domain protein; KEGG: she:Shewmr4_0687 rRNA (guanine-N(2)-)-methyltransferase YP_001051877.1 PFAM: protein of unknown function DUF342; KEGG: shn:Shewana3_3451 protein of unknown function DUF342 YP_001051878.1 KEGG: she:Shewmr4_3274 hypothetical protein YP_001051879.1 PFAM: peptidase M50; KEGG: shm:Shewmr7_0672 peptidase M50 YP_001051880.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: son:SO0822 outer membrane efflux family protein YP_001051881.1 PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: shn:Shewana3_3455 ABC transporter related YP_001051882.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO0820 HlyD family secretion protein YP_001051883.1 TIGRFAM: molybdate transport repressor, ModE; PFAM: regulatory protein, LysR; TOBE domain protein; KEGG: shn:Shewana3_0744 transcriptional regulator, ModE family YP_001051884.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein, family 1; KEGG: shm:Shewmr7_0769 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_001051885.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_001051886.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_001051887.1 PFAM: phage integrase family protein; KEGG: she:Shewmr4_3198 phage integrase family protein YP_001051888.1 PFAM: helix-turn-helix domain protein; KEGG: son:SO3867 transcriptional regulator, Cro/CI family YP_001051889.1 KEGG: son:SO3868 hypothetical protein YP_001051890.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001051891.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001051892.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001051893.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001051894.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001051895.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_3021 integrase, catalytic region YP_001051896.1 KEGG: lpn:lpg2568 hypothetical protein YP_001051897.1 KEGG: ppu:PP_3705 hypothetical protein YP_001051898.1 PFAM: UMUC domain protein DNA-repair protein; KEGG: she:Shewmr4_3210 DNA-directed DNA polymerase YP_001051899.1 PFAM: peptidase S24, S26A and S26B; KEGG: sdn:Sden_3236 peptidase S24, S26A and S26B YP_001051900.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001051902.1 KEGG: she:Shewmr4_3215 hypothetical protein YP_001051903.1 PFAM: phage integrase family protein; KEGG: she:Shewmr4_3218 phage integrase family protein YP_001051904.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: she:Shewmr4_3219 AAA ATPase, central domain protein YP_001051905.1 KEGG: she:Shewmr4_3220 hypothetical protein YP_001051906.1 PFAM: DNA repair protein RadC; KEGG: ppd:Ppro_2277 DNA repair protein RadC YP_001051907.1 KEGG: she:Shewmr4_3221 hypothetical protein YP_001051908.1 PFAM: protein of unknown function DUF1508; KEGG: shn:Shewana3_0740 protein of unknown function DUF1508 YP_001051909.1 KEGG: son:SO3890 methyl-accepting chemotaxis protein; TIGRFAM: hemerythrin-like metal-binding protein; PFAM: chemotaxis sensory transducer; Hemerythrin HHE cation binding domain protein; SMART: histidine kinase, HAMP region domain protein YP_001051910.1 KEGG: shn:Shewana3_0738 hypothetical protein YP_001051911.1 KEGG: she:Shewmr4_3224 hypothetical protein YP_001051912.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: shm:Shewmr7_0764 periplasmic sensor signal transduction histidine kinase YP_001051913.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: she:Shewmr4_3226 UBA/ThiF-type NAD/FAD binding protein YP_001051914.1 PFAM: porin, Gram-negative type; KEGG: shn:Shewana3_0734 porin, gram-negative type YP_001051915.1 PFAM: porin, Gram-negative type; KEGG: shm:Shewmr7_0761 porin, gram-negative type YP_001051916.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001051917.1 KEGG: shm:Shewmr7_0759 L-sorbosone dehydrogenase, putative YP_001051918.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001051919.1 PFAM: protein of unknown function UPF0227; KEGG: she:Shewmr4_3232 protein of unknown function UPF0227 YP_001051920.1 PFAM: metallophosphoesterase; Calcineurin phosphoesterase C-terminal domain protein; KEGG: shn:Shewana3_0728 calcineurin phosphoesterase C-terminal domain protein YP_001051921.1 PFAM: protein of unknown function DUF1249; KEGG: son:SO3902 hypothetical protein YP_001051922.1 PFAM: NUDIX hydrolase; KEGG: son:SO3903 ADP-ribose pyrophosphatase YP_001051923.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_001051924.1 KEGG: shn:Shewana3_0724 conserved hypothetical protein YP_001051925.1 PFAM: protein of unknown function DUF461; KEGG: son:SO3907 hypothetical protein YP_001051926.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: shn:Shewana3_0721 enoyl-CoA hydratase/isomerase YP_001051927.1 PFAM: PspC domain protein; KEGG: shn:Shewana3_0720 conserved hypothetical protein YP_001051928.1 KEGG: shn:Shewana3_0719 conserved hypothetical protein YP_001051929.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase, DuS; KEGG: shm:Shewmr7_0746 TIM-barrel protein, YjbN family YP_001051930.1 PFAM: phage integrase family protein; KEGG: sdn:Sden_3233 phage integrase YP_001051931.1 KEGG: sdn:Sden_3237 hypothetical protein YP_001051932.1 KEGG: sdn:Sden_3238 hypothetical protein YP_001051933.1 KEGG: son:SO0683 hypothetical protein YP_001051934.1 KEGG: son:SO0682 hypothetical protein YP_001051935.1 KEGG: sfr:Sfri_1685 hypothetical protein YP_001051936.1 TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: sdn:Sden_3243 phage tail tape measure protein TP901, core region YP_001051937.1 KEGG: sdn:Sden_3244 hypothetical protein YP_001051938.1 KEGG: sdn:Sden_3245 hypothetical protein YP_001051939.1 KEGG: sdn:Sden_3246 hypothetical protein YP_001051940.1 KEGG: sdn:Sden_3247 hypothetical protein YP_001051941.1 KEGG: sdn:Sden_3248 gifsy-2 prophage; putative RecA/RadA recombinase YP_001051942.1 PFAM: peptidase S14, ClpP; KEGG: sdn:Sden_3249 peptidase S14, ClpP YP_001051943.1 TIGRFAM: phage portal protein, lambda family; PFAM: phage portal protein, lambda; KEGG: sdn:Sden_3250 phage portal protein, lambda YP_001051944.1 KEGG: sdn:Sden_3251 hypothetical protein YP_001051945.1 PFAM: phage terminase GpA; KEGG: sdn:Sden_3252 phage terminase GpA YP_001051946.1 PFAM: phage DNA packaging Nu1; KEGG: sfr:Sfri_1674 phage DNA packaging Nu1 YP_001051948.1 KEGG: son:SO0660 hypothetical protein YP_001051949.1 PFAM: glycoside hydrolase, family 24; KEGG: son:SO0659 lysozyme, putative YP_001051951.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001051952.1 KEGG: sdn:Sden_3259 hypothetical protein YP_001051953.1 PFAM: helix-turn-helix domain protein; KEGG: sdn:Sden_3260 transciptional regulator YP_001051954.1 PFAM: phage integrase family protein; KEGG: sdn:Sden_3261 phage integrase YP_001051955.1 PFAM: replication P family protein; KEGG: sdn:Sden_3262 replication P YP_001051956.1 KEGG: eci:UTI89_C5100 putative replication protein YP_001051957.1 KEGG: sdn:Sden_3265 hypothetical protein YP_001051958.1 KEGG: sdn:Sden_3266 hypothetical protein YP_001051959.1 KEGG: sdn:Sden_3267 hypothetical protein YP_001051960.1 PFAM: helix-turn-helix domain protein; peptidase S24, S26A and S26B; KEGG: sdn:Sden_3268 transciptional regulator YP_001051961.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: yps:YPTB1797 putative DNA methyltransferase YP_001051963.1 KEGG: sdn:Sden_3272 hypothetical protein YP_001051964.1 KEGG: sdn:Sden_3273 hypothetical protein YP_001051965.1 KEGG: sdn:Sden_3274 hypothetical protein YP_001051966.1 KEGG: psp:PSPPH_2145 hypothetical protein YP_001051967.1 KEGG: son:SO3001 hypothetical protein YP_001051968.1 KEGG: sdn:Sden_3276 hypothetical protein YP_001051969.1 KEGG: sdn:Sden_3277 hypothetical protein YP_001051970.1 KEGG: sfr:Sfri_1641 hypothetical protein YP_001051971.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001051972.1 PFAM: GCN5-related N-acetyltransferase; KEGG: vch:VCA0487 hypothetical protein YP_001051973.1 KEGG: vch:VCA0486 hypothetical protein YP_001051975.1 KEGG: son:SO4275 hypothetical protein YP_001051976.1 KEGG: vvu:VV1_2413 heme/copper-type cytochrome/quinol oxidase, subunit 1 YP_001051977.1 KEGG: son:SO0147 hypothetical protein YP_001051978.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: shn:Shewana3_0717 2OG-Fe(II) oxygenase YP_001051979.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shn:Shewana3_0716 TonB-dependent siderophore receptor YP_001051980.1 KEGG: shn:Shewana3_0715 putative chemotaxis protein CheX YP_001051981.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001051982.1 KEGG: son:SO3917 replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase, N-terminal domain protein; DnaB domain protein helicase, C-terminal domain protein; SMART: AAA ATPase YP_001051983.1 KEGG: shm:Shewmr7_0691 hypothetical protein YP_001051984.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001051985.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001051986.1 binds single-stranded DNA at the primosome assembly site YP_001051987.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001051988.1 PFAM: protein of unknown function DUF481; KEGG: shn:Shewana3_0700 protein of unknown function DUF481 YP_001051989.1 PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_3262 major facilitator superfamily MFS_1 YP_001051990.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_001051991.1 KEGG: shm:Shewmr7_0683 ribonuclease R; TIGRFAM: VacB and RNase II family 3'-5' exoribonucleases; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; Ribonuclease B, OB region N-terminal domain; Ribonuclease R winged-helix domain protein; SMART: Cold shock protein YP_001051992.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: shm:Shewmr7_0682 Sel1 domain protein repeat-containing protein YP_001051993.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001051994.1 KEGG: shn:Shewana3_0694 conserved hypothetical protein YP_001051995.1 forms a direct contact with the tRNA during translation YP_001051996.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001051997.1 PFAM: AFG1-family ATPase; KEGG: she:Shewmr4_3270 AFG1-family ATPase YP_001051998.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: shn:Shewana3_0690 protease Do YP_001051999.1 TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: son:SO3943 protease DegS YP_001052000.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001052001.1 PFAM: BolA family protein; KEGG: shn:Shewana3_0683 BolA family protein YP_001052002.1 KEGG: shm:Shewmr7_3339 SpoIIAA family protein YP_001052003.1 PFAM: toluene tolerance family protein; KEGG: shm:Shewmr7_3340 toluene tolerance family protein YP_001052004.1 PFAM: Mammalian cell entry related domain protein; KEGG: son:SO3952 mce-related protein YP_001052005.1 PFAM: protein of unknown function DUF140; KEGG: shn:Shewana3_0679 protein of unknown function DUF140 YP_001052006.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_3343 ABC transporter related YP_001052007.1 KEGG: she:Shewmr4_0678 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_001052008.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_001052009.1 PFAM: protein of unknown function DUF1239; KEGG: shn:Shewana3_0675 protein of unknown function DUF1239 YP_001052010.1 PFAM: OstA family protein; KEGG: shn:Shewana3_0674 OstA family protein YP_001052011.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shn:Shewana3_0673 ABC transporter related YP_001052012.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001052013.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: shn:Shewana3_0671 sigma 54 modulation protein/ribosomal protein S30EA YP_001052014.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: shn:Shewana3_0670 PTS IIA-like nitrogen-regulatory protein PtsN YP_001052015.1 PFAM: Uncharacterised P-loop ATPase protein UPF0042; KEGG: shm:Shewmr7_3352 uncharacterized P-loop ATPase protein UPF0042 YP_001052016.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: she:Shewmr4_0669 phosphocarrier, HPr family YP_001052017.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: son:SO3966 magnesium transporter YP_001052018.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; KEGG: she:Shewmr4_0667 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_001052019.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen; KEGG: son:SO3969 OmpA family protein YP_001052020.1 PFAM: transposase IS3/IS911 family protein; KEGG: shn:Shewana3_0664 transposase IS3/IS911 family protein YP_001052021.1 PFAM: protein of unknown function RIO1; KEGG: shm:Shewmr7_3358 protein of unknown function RIO1 YP_001052022.1 KEGG: shn:Shewana3_0662 hypothetical protein YP_001052023.1 KEGG: shn:Shewana3_0661 conserved hypothetical protein YP_001052024.1 KEGG: shm:Shewmr7_3361 hypothetical protein YP_001052025.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: shn:Shewana3_0659 diguanylate cyclase/phosphodiesterase with GAF sensor YP_001052026.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001052027.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001052028.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001052029.1 KEGG: sde:Sde_3090 hypothetical protein YP_001052030.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001052031.1 KEGG: son:SO0764 hypothetical protein YP_001052032.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shn:Shewana3_3536 lysine exporter protein (LysE/YggA) YP_001052033.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: shm:Shewmr7_0586 transcriptional regulator, AraC family YP_001052034.1 KEGG: shn:Shewana3_3538 hypothetical protein YP_001052035.1 PFAM: Alkaline phosphatase; KEGG: shm:Shewmr7_0584 alkaline phosphatase YP_001052036.1 PFAM: Alkaline phosphatase; KEGG: shn:Shewana3_3540 peptidoglycan glycosyltransferase YP_001052037.1 KEGG: shn:Shewana3_3543 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001052038.1 KEGG: son:SO0735 hypothetical protein YP_001052039.1 PFAM: transcriptional regulator PadR family protein; KEGG: son:SO0734 hypothetical protein YP_001052040.1 PFAM: Cold-shock protein, DNA-binding; Ribonuclease B, OB region N-terminal domain; SMART: Cold shock protein; KEGG: she:Shewmr4_3373 cold-shock DNA-binding domain protein YP_001052041.1 KEGG: son:SO0728 hypothetical protein YP_001052042.1 PFAM: protein of unknown function DUF134; Sigma-70, region 4 type 2; KEGG: son:SO0727 hypothetical protein YP_001052043.1 KEGG: xcv:XCV3148 putative aminopeptidase precursor YP_001052044.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shn:Shewana3_3547 ABC transporter related YP_001052045.1 KEGG: son:SO0721 hypothetical protein YP_001052046.1 PFAM: Carboxymuconolactone decarboxylase; KEGG: sfr:Sfri_3646 carboxymuconolactone decarboxylase YP_001052047.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: rso:RSc3143 probable transmembrane protein YP_001052048.1 PFAM: Excalibur domain protein; KEGG: pat:Patl_2336 hypothetical protein YP_001052050.1 PFAM: SMC domain protein; SMART: AAA ATPase; KEGG: ppu:PP_3982 hypothetical protein YP_001052051.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001052052.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001052053.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: shn:Shewana3_3569 MATE efflux family protein YP_001052054.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shn:Shewana3_3570 transcriptional regulator, LysR family YP_001052055.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_3401 efflux transporter, RND family, MFP subunit YP_001052056.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001052057.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001052058.1 TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; KEGG: vvy:VV0816 type I restriction-modification system methyltransferase subunit YP_001052060.1 PFAM: restriction modification system DNA specificity domain; KEGG: vvy:VV0814 restriction endonuclease S subunit YP_001052061.1 PFAM: protein of unknown function DUF1016; KEGG: psp:PSPPH_0603 hypothetical protein YP_001052062.1 KEGG: vvy:VV0813 type I site-specific restriction-modification system, R (restriction) subunit; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like YP_001052063.1 PFAM: phage integrase family protein; KEGG: son:SOA0045 site-specific recombinase, phage integrase family YP_001052064.1 PFAM: phage integrase family protein; KEGG: son:SOA0044 site-specific recombinase, phage integrase family YP_001052065.1 PFAM: acriflavin resistance protein; KEGG: shn:Shewana3_3572 acriflavin resistance protein YP_001052066.1 KEGG: saz:Sama_3127 hypothetical protein YP_001052067.1 PFAM: FxsA cytoplasmic membrane protein; KEGG: shm:Shewmr7_0548 FxsA cytoplasmic membrane protein YP_001052068.1 PFAM: CutA1 divalent ion tolerance protein; KEGG: shm:Shewmr7_0547 CutA1 divalent ion tolerance protein YP_001052069.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_001052070.1 PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: son:SO0695 glutathione-regulated potassium-efflux system protein KefC, putative YP_001052071.1 KEGG: son:SO0694 galactokinase; TIGRFAM: galactokinase; PFAM: GHMP kinase; GHMP kinase, C terminal domain protein YP_001052072.1 PFAM: Aldose 1-epimerase; KEGG: son:SO0693 aldose 1-epimerase YP_001052073.1 KEGG: son:SO0691 hypothetical protein YP_001052074.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: son:SO0640 alcohol dehydrogenase, zinc-containing YP_001052075.1 PFAM: peptidase domain protein; Peptidase M9A, collagenase C-terminal domain protein; Peptidase M9, N-terminal domain; KEGG: son:SO0639 collagenase family YP_001052076.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: she:Shewmr4_3412 Sel1 domain protein repeat-containing protein YP_001052077.1 PFAM: acriflavin resistance protein; KEGG: son:SO4014 AcrB/AcrD/AcrF family protein YP_001052078.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO4015 hypothetical protein YP_001052079.1 PFAM: protein kinase; leucine-rich repeat protein; SMART: tyrosine protein kinase; serine/threonine protein kinase; leucine-rich repeat-containing protein, typical subtype; KEGG: son:SO4016 hypothetical protein YP_001052080.1 PFAM: Peptidoglycan-binding LysM; Lytic transglycosylase, catalytic; MLTD_N domain protein; KEGG: son:SO4017 transglycosylase, Slt family YP_001052081.1 KEGG: rso:RS01698 probable transmembrane protein YP_001052082.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001052083.1 KEGG: rso:RS01698 probable transmembrane protein YP_001052084.1 KEGG: shn:Shewana3_3585 conserved hypothetical protein YP_001052085.1 KEGG: son:SO4019 hypothetical protein YP_001052086.1 PFAM: peptidase M16 domain protein; KEGG: son:SO4022 peptidase, M16 family YP_001052087.1 KEGG: pau:PA14_19140 cyclohexadienyl dehydratase; TIGRFAM: chorismate mutase, putative; PFAM: extracellular solute-binding protein, family 3; Chorismate mutase YP_001052088.1 KEGG: aha:AHA_3828 L-asparaginase, type II; TIGRFAM: L-asparaginases, type II; PFAM: Asparaginase/glutaminase YP_001052089.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001052090.1 catalyzes the formation of fumarate from aspartate YP_001052091.1 TIGRFAM: anaerobic c4-dicarboxylate antiporter, Dcu family; PFAM: anaerobic c4-dicarboxylate membrane transporter; KEGG: sfr:Sfri_0681 anaerobic C4-dicarboxylate antiporter, Dcu family protein YP_001052092.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit YP_001052093.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001052094.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001052095.1 PFAM: porin, Gram-negative type; KEGG: sfr:Sfri_0677 porin, gram-negative type YP_001052096.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: son:SO4028 single-strand binding protein YP_001052097.1 PFAM: major facilitator superfamily MFS_1; KEGG: shn:Shewana3_3591 major facilitator superfamily MFS_1 YP_001052098.1 TIGRFAM: excinuclease ABC, A subunit; PFAM: ABC transporter related; KEGG: son:SO4030 excinuclease ABC, A subunit YP_001052099.1 PFAM: peptidase M28; KEGG: shn:Shewana3_3594 peptidase M28 YP_001052100.1 PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO4034 ATP-dependent RNA helicase DeaD YP_001052101.1 KEGG: sdn:Sden_3340 methylation YP_001052102.1 KEGG: shn:Shewana3_3596 conserved hypothetical protein YP_001052103.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO4039 hydrolase, haloacid dehalogenase-like family YP_001052104.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: son:SO4040 integral membrane domain protein YP_001052105.1 KEGG: son:SO4042 hydratase/decarboxylase family protein YP_001052106.1 TIGRFAM: TonB family protein; KEGG: son:SO4043 TonB domain protein YP_001052107.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001052108.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001052109.1 KEGG: shn:Shewana3_3604 conserved hypothetical protein YP_001052110.1 PFAM: protein of unknown function DUF450 YP_001052111.1 KEGG: son:SO4048 cytochrome c family protein YP_001052112.1 KEGG: shn:Shewana3_3608 response regulator receiver protein YP_001052113.1 PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_0517 secretion protein HlyD family protein YP_001052114.1 PFAM: regulatory protein, MarR; KEGG: she:Shewmr4_3435 transcriptional regulator, MarR family YP_001052115.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shn:Shewana3_3611 methyl-accepting chemotaxis sensory transducer YP_001052116.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_001052117.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001052118.1 KEGG: shn:Shewana3_3614 O-succinylhomoserine (thiol)-lyase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_001052119.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_001052120.1 PFAM: protein of unknown function DUF81; KEGG: shn:Shewana3_3616 protein of unknown function DUF81 YP_001052121.1 PFAM: Polysulphide reductase, NrfD; KEGG: son:SO4060 polysulfide reductase, subunit C YP_001052122.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4061 polysulfide reductase, subunit B YP_001052123.1 PFAM: pentapeptide repeat protein; KEGG: she:Shewmr4_3445 pentapeptide repeat protein YP_001052124.1 PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: sme:SMc01149 hypothetical protein YP_001052125.1 KEGG: shn:Shewana3_3621 hypothetical protein YP_001052126.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001052127.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: aha:AHA_3525 response regulator YP_001052128.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: cvi:CV3340 two-component sensor histidine kinase protein YP_001052129.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001052130.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001052131.1 KEGG: sfr:Sfri_0734 OmpA domain protein transmembrane region-containing protein YP_001052132.1 KEGG: saz:Sama_1558 conserved hypothetical protein YP_001052133.1 PFAM: cyclic nucleotide-binding; KEGG: vpa:VPA0656 putative cyclic nucleotide binding protein YP_001052134.1 PFAM: purine and other phosphorylases, family 1; KEGG: vvy:VVA0211 uridine phosphorylase YP_001052135.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: ppr:PBPRA1430 putative nicotinamide mononucleotide transporter YP_001052136.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO4069 hypothetical protein YP_001052137.1 KEGG: sdn:Sden_1944 hypothetical protein YP_001052138.1 PFAM: EAL domain protein; KEGG: saz:Sama_2731 putative diguanylate phosphodiesterase YP_001052139.1 PFAM: protein of unknown function DUF541; KEGG: shn:Shewana3_3626 protein of unknown function DUF541 YP_001052140.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_001052141.1 TIGRFAM: fumarate hydratase, class II; PFAM: fumarate lyase; KEGG: pmu:PM0823 fumarate hydratase YP_001052142.1 PFAM: protein of unknown function DUF331; KEGG: shn:Shewana3_3628 protein of unknown function DUF331 YP_001052143.1 KEGG: shm:Shewmr7_0497 hypothetical protein YP_001052144.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO4077 TonB-dependent receptor, putative YP_001052145.1 PFAM: peptidase U62, modulator of DNA gyrase; KEGG: she:Shewmr4_3455 peptidase U62, modulator of DNA gyrase YP_001052146.1 PFAM: protein of unknown function DUF615; KEGG: shn:Shewana3_3632 protein of unknown function DUF615 YP_001052147.1 PFAM: Ig domain protein, group 1 domain protein; KEGG: son:SO4080 hypothetical protein YP_001052148.1 PFAM: transposase, IS4 family protein; KEGG: son:SO3544 ISSod7, transposase YP_001052149.1 PFAM: amino acid permease-associated region; KEGG: shm:Shewmr7_0492 amino acid permease-associated region YP_001052150.1 KEGG: shn:Shewana3_3636 hypothetical protein YP_001052151.1 PFAM: ABC-2 type transporter; KEGG: shm:Shewmr7_0490 hypothetical protein YP_001052152.1 PFAM: ABC-2 type transporter; KEGG: son:SO4088 conserved hypothetical protein YP_001052153.1 PFAM: secretion protein HlyD family protein; KEGG: shn:Shewana3_3639 secretion protein HlyD family protein YP_001052154.1 PFAM: outer membrane efflux protein; KEGG: shm:Shewmr7_0487 outer membrane efflux protein YP_001052155.1 PFAM: peptidase U62, modulator of DNA gyrase; KEGG: son:SO4091 TldD protein YP_001052156.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: she:Shewmr4_3466 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001052157.1 KEGG: she:Shewmr4_3467 hypothetical protein YP_001052158.1 involved in the processing of the 5'end of 16S rRNA YP_001052159.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: she:Shewmr4_3469 maf protein YP_001052160.1 PFAM: Rod shape-determining protein MreD; KEGG: she:Shewmr4_3470 rod shape-determining protein MreD YP_001052161.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001052162.1 functions in MreBCD complex in some organisms YP_001052163.1 KEGG: sfr:Sfri_3739 hypothetical protein YP_001052164.1 KEGG: son:SO4101 MSHA biogenesis protein MshP YP_001052165.1 KEGG: son:SO4102 MSHA biogenesis protein MshO YP_001052166.1 KEGG: son:SO4103 MSHA pilin protein MshD YP_001052167.1 KEGG: shn:Shewana3_3653 methylation site containing protein YP_001052168.1 KEGG: sfr:Sfri_3744 methylation site containing protein YP_001052169.1 KEGG: son:SO4106 MSHA pilin protein MshB YP_001052170.1 KEGG: she:Shewmr4_3481 hypothetical protein YP_001052171.1 PFAM: type II secretion system protein; KEGG: son:SO4108 MSHA biogenesis protein MshG YP_001052172.1 PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; KEGG: shm:Shewmr7_0469 type II secretion system protein E YP_001052173.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_3; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: son:SO4110 MSHA biogenesis protein MshN, putative YP_001052174.1 KEGG: son:SO4111 MSHA biogenesis protein MshM YP_001052175.1 TIGRFAM: pilus (MSHA type) biogenesis protein MshL; PFAM: type II and III secretion system protein; Secretin domain protein; Secretin/TonB, short N-terminal domain; KEGG: son:SO4112 MSHA biogenesis protein MshL YP_001052176.1 KEGG: shm:Shewmr7_0465 MSHA biogenesis protein MshK YP_001052177.1 KEGG: shm:Shewmr7_0464 MSHA biogenesis protein MshJ YP_001052178.1 KEGG: she:Shewmr4_3489 hypothetical protein YP_001052179.1 KEGG: son:SO4114.2 hypothetical biogenesis protein MshI YP_001052180.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_001052181.1 PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: shn:Shewana3_3669 malic enzyme, NAD-binding YP_001052182.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001052183.1 KEGG: shm:Shewmr7_0458 hypothetical protein YP_001052184.1 KEGG: she:Shewmr4_3495 primosomal protein N'; TIGRFAM: primosomal protein N'; PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001052185.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001052186.1 PFAM: Sporulation domain protein; KEGG: son:SO4124 cell division protein FtsN, putative YP_001052187.1 KEGG: son:SO4126 hypothetical protein YP_001052188.1 PFAM: band 7 protein; KEGG: shn:Shewana3_3676 band 7 protein YP_001052189.1 PFAM: band 7 protein; KEGG: she:Shewmr4_3502 band 7 protein YP_001052190.1 PFAM: protein of unknown function DUF107; KEGG: shn:Shewana3_3678 protein of unknown function DUF107 YP_001052191.1 KEGG: son:SO4131 hypothetical protein YP_001052192.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_001052193.1 PFAM: protein of unknown function DUF465; KEGG: shn:Shewana3_3681 protein of unknown function DUF465 YP_001052194.1 PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: son:SO4136 decarboxylase, pyridoxal-dependent YP_001052195.1 KEGG: shm:Shewmr7_0444 hypothetical protein YP_001052196.1 PFAM: MscS Mechanosensitive ion channel; KEGG: she:Shewmr4_3509 MscS mechanosensitive ion channel YP_001052197.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: son:SO4139 hypothetical protein YP_001052198.1 KEGG: pat:Patl_1924 hypothetical protein YP_001052199.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: shm:Shewmr7_0438 sulphate transporter YP_001052200.1 KEGG: son:SO4154 transcriptional regulator, LysR family YP_001052201.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_3516 histidine kinase YP_001052202.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: shm:Shewmr7_0436 two component transcriptional regulator, LuxR family YP_001052203.1 KEGG: son:SO4160 flagellar biosynthesis protein, putative YP_001052204.1 KEGG: she:Shewmr4_3518 hypothetical protein YP_001052205.1 PFAM: bifunctional deaminase-reductase domain protein; KEGG: lpn:lpg1988 dihydrofolate reductase YP_001052206.1 KEGG: son:SO4159 hypothetical protein YP_001052207.1 heat shock protein involved in degradation of misfolded proteins YP_001052208.1 heat shock protein involved in degradation of misfolded proteins YP_001052209.1 PFAM: protein of unknown function DUF971; KEGG: shn:Shewana3_3701 protein of unknown function DUF971 YP_001052210.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001052211.1 KEGG: dps:DP1565 hypothetical protein YP_001052212.1 PFAM: deoxyribodipyrimidine photolyase-related protein; KEGG: she:Shewmr4_3526 deoxyribodipyrimidine photolyase-related protein YP_001052213.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: son:SO4170 C factor cell-cell signaling protein YP_001052214.1 PFAM: PKD domain containing protein; peptidase M4, thermolysin; Propeptide, PepSY amd peptidase M4; peptidase domain protein; Peptidase M4, thermolysin; KEGG: sdn:Sden_3015 peptidase M4, thermolysin YP_001052215.1 PFAM: response regulator receiver; helix-turn-helix, Fis-type; KEGG: son:SO4172 DNA-binding response regulator YP_001052216.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_3530 periplasmic sensor signal transduction histidine kinase YP_001052217.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: son:SO4174 NAD dependent epimerase/dehydratase family protein YP_001052218.1 KEGG: shm:Shewmr7_0423 hypothetical protein YP_001052219.1 KEGG: shn:Shewana3_3711 conserved hypothetical protein YP_001052220.1 PFAM: pseudouridine synthase; KEGG: shn:Shewana3_3712 pseudouridine synthase YP_001052221.1 KEGG: shm:Shewmr7_0417 ATP-dependent protease La (LON) domain protein, putative YP_001052222.1 KEGG: shn:Shewana3_3714 conserved hypothetical protein YP_001052223.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_0415 TonB-dependent receptor YP_001052224.1 PFAM: conserved hypothetical protein 22; KEGG: shn:Shewana3_3716 conserved hypothetical protein 22 YP_001052225.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001052226.1 KEGG: shm:Shewmr7_0412 DedA family protein YP_001052227.1 TIGRFAM: TonB family protein; KEGG: she:Shewmr4_3544 TonB family protein YP_001052228.1 KEGG: shn:Shewana3_3719 conserved hypothetical protein YP_001052229.1 KEGG: shm:Shewmr7_0410 hypothetical protein YP_001052230.1 PFAM: phosphoesterase, PA-phosphatase related; KEGG: son:SO4195 PAP2 family protein YP_001052231.1 KEGG: shn:Shewana3_3722 uroporphyrinogen decarboxylase YP_001052232.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001052233.1 PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: she:Shewmr4_3550 arginase/agmatinase/formiminoglutamase YP_001052234.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferases; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO4199 ubiquinone/menaquinone biosynthesis methlytransferase UbiE YP_001052235.1 PFAM: protein of unknown function DUF1243; KEGG: shn:Shewana3_3726 protein of unknown function DUF1243 YP_001052236.1 TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: ABC-1 domain protein; KEGG: shm:Shewmr7_0403 2-polyprenylphenol 6-hydroxylase YP_001052237.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: shm:Shewmr7_0402 twin-arginine translocation protein, TatA/E family subunit YP_001052238.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: shn:Shewana3_3729 twin-arginine translocation protein, TatB subunit YP_001052239.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: she:Shewmr4_3556 sec-independent protein translocase, TatC subunit YP_001052240.1 KEGG: shm:Shewmr7_0399 hypothetical protein YP_001052241.1 PFAM: TatD-related deoxyribonuclease; KEGG: shm:Shewmr7_0398 TatD-related deoxyribonuclease YP_001052242.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Diverse 7TM receptor, extracellular region 2; Diverse 7TM receptor, transmembrane region; KEGG: shm:Shewmr7_0397 diguanylate cyclase YP_001052243.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001052244.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001052245.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_001052246.1 KEGG: son:SO0430 hypothetical protein YP_001052247.1 PFAM: peptidase M13, neprilysin; peptidase M13; KEGG: she:Shewmr4_0433 endothelin-converting enzyme 1 YP_001052248.1 PFAM: surface antigen (D15); Patatin; surface antigen variable number repeat protein; KEGG: she:Shewmr4_0432 patatin YP_001052249.1 KEGG: she:Shewmr4_0431 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001052250.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001052251.1 KEGG: she:Shewmr4_0429 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001052252.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001052253.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_001052254.1 involved in regulation of beta-lactamase; putative signaling protein YP_001052255.1 PFAM: N-acetylmuramoyl-L-alanine amidase, family 2; KEGG: shn:Shewana3_0423 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD YP_001052256.1 KEGG: shn:Shewana3_0422 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase YP_001052257.1 KEGG: shn:Shewana3_0421 methylation site containing protein YP_001052258.1 TIGRFAM: type IV-A pilus assembly ATPase PilB; PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; KEGG: son:SO0416 type IV pilus biogenesis protein PilB YP_001052259.1 PFAM: type II secretion system protein; KEGG: shn:Shewana3_0418 type II secretion system protein YP_001052260.1 PFAM: peptidase A24A, prepilin type IV; peptidase A24A domain protein; KEGG: she:Shewmr4_0418 prepilin peptidase YP_001052261.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001052262.1 PFAM: protein of unknown function DUF1342; KEGG: shn:Shewana3_0415 protein of unknown function DUF1342 YP_001052263.1 PFAM: protein of unknown function DUF329; KEGG: shn:Shewana3_0414 protein of unknown function DUF329 YP_001052264.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: she:Shewmr4_0414 mutator MutT protein YP_001052265.1 KEGG: shn:Shewana3_0412 conserved hypothetical protein YP_001052266.1 PFAM: Ppx/GppA phosphatase; KEGG: shm:Shewmr7_3613 Ppx/GppA phosphatase YP_001052267.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_001052268.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: shn:Shewana3_0409 thioredoxin YP_001052269.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001052270.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_0408 transcriptional regulator, LysR family YP_001052271.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: shm:Shewmr7_3618 NADPH:quinone reductase YP_001052272.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: she:Shewmr4_0406 antibiotic biosynthesis monooxygenase YP_001052273.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001052274.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001052275.1 PFAM: fumarate reductase respiratory complex, transmembrane subunit; KEGG: shn:Shewana3_0402 fumarate reductase respiratory complex, transmembrane subunit YP_001052276.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit YP_001052277.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001052278.1 TIGRFAM: putative TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase, DuS; dihydroorotate dehydrogenase; KEGG: shn:Shewana3_0399 putative TIM-barrel protein, nifR3 family YP_001052279.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_001052280.1 PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: sfr:Sfri_0452 UvrD/REP helicase YP_001052281.1 KEGG: sdn:Sden_3629 hypothetical protein YP_001052282.1 KEGG: sdn:Sden_3630 type IV pilus assembly PilZ YP_001052283.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001052284.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001052285.1 PFAM: OmpA/MotB domain protein; KEGG: sdn:Sden_3631 OmpA/MotB YP_001052286.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001052287.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001052288.1 PFAM: flagellar basal body-associated protein FliL; KEGG: sdn:Sden_3634 flagellar basal body-associated protein FliL YP_001052289.1 PFAM: flagellar hook-length control protein; KEGG: sdn:Sden_3635 flagellar hook-length control protein YP_001052290.1 KEGG: sdn:Sden_3636 hypothetical protein YP_001052291.1 PFAM: flagellar protein FliS; KEGG: sdn:Sden_3637 flagellar protein FliS YP_001052292.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; KEGG: sdn:Sden_3638 flagellar hook-associated 2-like protein YP_001052293.1 PFAM: flagellin domain protein; KEGG: sdn:Sden_3639 flagellin-like protein YP_001052294.1 PFAM: flagellin domain protein; KEGG: sdn:Sden_3639 flagellin-like protein YP_001052295.1 PFAM: flagellin domain protein; KEGG: sdn:Sden_3639 flagellin-like protein YP_001052296.1 PFAM: flagellin domain protein; KEGG: sdn:Sden_3639 flagellin-like protein YP_001052297.1 KEGG: sdn:Sden_3640 hypothetical protein YP_001052298.1 TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: sdn:Sden_3641 flagellin-like protein YP_001052299.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; KEGG: sdn:Sden_3642 flagellar hook-associated protein YP_001052300.1 FlgJ; flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; like the lateral flagella FlgJ in Vibrio parahaemolyticus this protein does not contains a C-terminal muramidase domain YP_001052301.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001052302.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_001052303.1 TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: sdn:Sden_3646 flagellar basal-body rod FlgG YP_001052304.1 TIGRFAM: flagellar basal-body rod protein FlgF; PFAM: flagellar basal body rod protein; KEGG: sdn:Sden_3647 flagellar basal-body rod FlgF YP_001052305.1 the hook connects flagellar basal body to the flagellar filament; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001052306.1 PFAM: flagellar hook capping protein; KEGG: sdn:Sden_3649 flagellar hook capping protein YP_001052307.1 TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: protein of unknown function DUF1078 domain protein; KEGG: sdn:Sden_3650 flagellar basal-body rod protein FlgC YP_001052308.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001052309.1 PFAM: SAF domain; KEGG: sdn:Sden_3652 flageller protein FlgA YP_001052310.1 KEGG: sdn:Sden_3653 hypothetical protein YP_001052311.1 KEGG: sdn:Sden_3654 hypothetical protein YP_001052312.1 KEGG: sdn:Sden_3655 hypothetical protein YP_001052313.1 KEGG: sdn:Sden_3656 ATPase FliI/YscN; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; H+-transporting two-sector ATPase, alpha/beta subunit domain protein; SMART: AAA ATPase YP_001052314.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001052315.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001052316.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; the Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001052317.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: sdn:Sden_3660 flagellar hook-basal body complex protein (FliE) YP_001052318.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: sdn:Sden_3661 sigma-54 factor, interaction region YP_001052319.1 KEGG: sdn:Sden_3662 hypothetical protein YP_001052320.1 PFAM: surface presentation of antigens (SPOA) protein; KEGG: sdn:Sden_3663 surface presentation of antigens (SpoA) protein YP_001052321.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001052322.1 PFAM: export protein FliQ, family 3; KEGG: sdn:Sden_3665 export protein FliQ, family 3 YP_001052323.1 TIGRFAM: flagellar biosynthetic protein FliR; PFAM: type III secretion system inner membrane R protein; KEGG: sdn:Sden_3666 flagellar biosynthetic protein FliR YP_001052324.1 TIGRFAM: flagellar biosynthetic protein FlhB; PFAM: type III secretion exporter; KEGG: sdn:Sden_3667 flagellar biosynthetic protein FlhB YP_001052325.1 TIGRFAM: flagellar biosynthesis protein FlhA; PFAM: type III secretion FHIPEP protein; KEGG: sdn:Sden_3668 flagellar biosynthesis protein FlhA YP_001052326.1 PFAM: Hemerythrin HHE cation binding domain protein; KEGG: she:Shewmr4_0398 hemerythrin HHE cation binding domain protein YP_001052327.1 PFAM: AAA-4 family protein; KEGG: she:Shewmr4_0397 putative transcriptional regulator YP_001052328.1 PFAM: HupE/UreJ protein; KEGG: shn:Shewana3_0395 HupE/UreJ protein YP_001052329.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO4305 HAD-superfamily hydrolase, subfamily IA, variant 1 family protein YP_001052330.1 TIGRFAM: tyrosine recombinase XerC; PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: shn:Shewana3_0393 tyrosine recombinase XerC YP_001052331.1 PFAM: protein of unknown function DUF484; KEGG: shn:Shewana3_0392 protein of unknown function DUF484 YP_001052332.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001052333.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: shm:Shewmr7_3634 diaminopimelate decarboxylase YP_001052334.1 KEGG: shn:Shewana3_0389 conserved hypothetical protein YP_001052335.1 PFAM: Frataxin family protein; KEGG: shn:Shewana3_0388 frataxin family protein YP_001052336.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001052337.1 PFAM: Uroporphyrinogen III synthase HEM4; KEGG: son:SO4314 uroporphyrinogen-III synthase YP_001052338.1 PFAM: protein of unknown function DUF513, hemX; KEGG: she:Shewmr4_0386 protein of unknown function DUF513, HemX YP_001052339.1 PFAM: HemY domain protein; Tetratricopeptide TPR_2 repeat protein; KEGG: shn:Shewana3_0383 HemY domain protein YP_001052340.1 TIGRFAM: putative outer membrane adhesin like proteiin; PFAM: Hemolysin-type calcium-binding region; von Willebrand factor, type A; KEGG: aha:AHA_3491 flagellin hook IN motif family YP_001052341.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; peptidase C39, bacteriocin processing; SMART: AAA ATPase; KEGG: she:Shewmr4_0383 ABC transporter related YP_001052342.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_3644 type I secretion membrane fusion protein, HlyD family YP_001052343.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: shm:Shewmr7_3645 type I secretion outer membrane protein, TolC family YP_001052344.1 PFAM: OmpA/MotB domain protein; KEGG: she:Shewmr4_0380 OmpA/MotB domain protein YP_001052345.1 KEGG: shn:Shewana3_0377 conserved hypothetical protein YP_001052346.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: shn:Shewana3_0376 diguanylate cyclase/phosphodiesterase YP_001052347.1 TIGRFAM: ATP-dependent DNA helicase Rep; PFAM: UvrD/REP helicase; KEGG: shn:Shewana3_0374 ATP-dependent DNA helicase Rep YP_001052348.1 PFAM: protein of unknown function DUF526; KEGG: son:SO4329 hypothetical protein YP_001052349.1 KEGG: shm:Shewmr7_3652 hypothetical protein YP_001052350.1 KEGG: she:Shewmr4_0373 hypothetical protein YP_001052351.1 PFAM: protein of unknown function DUF1006; KEGG: she:Shewmr4_0372 protein of unknown function DUF1006 YP_001052352.1 KEGG: shn:Shewana3_0366 conserved hypothetical protein YP_001052353.1 KEGG: son:SO4333 hypothetical protein YP_001052354.1 PFAM: Inner membrane CreD family protein; KEGG: shm:Shewmr7_3656 inner membrane CreD family protein YP_001052355.1 PFAM: phosphoesterase, PA-phosphatase related; KEGG: shm:Shewmr7_3657 phosphoesterase, PA-phosphatase related YP_001052356.1 KEGG: saz:Sama_3276 ABC-type amino acid transport/signal transduction system YP_001052357.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: son:SO4337 transcriptional regulator, AsnC family YP_001052358.1 PFAM: sodium:neurotransmitter symporter; KEGG: son:SO4339 sodium-dependent transporter, putative YP_001052359.1 PFAM: import inner membrane translocase, subunit Tim44; KEGG: son:SO4340 hypothetical protein YP_001052361.1 KEGG: shn:Shewana3_0361 conserved hypothetical protein YP_001052362.1 PFAM: aminotransferase, class V; KEGG: son:SO4343 aminotransferase, class V YP_001052363.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_001052364.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001052365.1 PFAM: amino acid-binding ACT domain protein; KEGG: shn:Shewana3_0357 acetolactate synthase small subunit YP_001052366.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_001052367.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001052368.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_001052369.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: son:SO4351 CBS domain protein YP_001052370.1 KEGG: shm:Shewmr7_3668 ABC-type amino acid transport/signal transduction systems periplasmic component/domain-like protein YP_001052371.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: shn:Shewana3_0350 diguanylate cyclase YP_001052372.1 KEGG: shn:Shewana3_0349 periplasmic sugar-binding protein, putative YP_001052373.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfr:Sfri_4014 transposase IS3/IS911 family protein YP_001052374.1 PFAM: Integrase, catalytic region; KEGG: sfr:Sfri_4013 integrase, catalytic region YP_001052375.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2262 integrase, catalytic region YP_001052376.1 KEGG: cps:CPS_2866 hypothetical protein YP_001052377.1 KEGG: son:SO0349 magnesium chelatase family protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001052378.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: son:SO0348 acyltransferase family protein YP_001052379.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: she:Shewmr4_3626 phospholipid/glycerol acyltransferase YP_001052380.1 PFAM: protein of unknown function DUF523; KEGG: she:Shewmr4_3627 protein of unknown function DUF523 YP_001052381.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: shm:Shewmr7_0316 transcriptional regulator, GntR family YP_001052382.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_001052383.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_001052384.1 Catalyzes the conversion of citrate to isocitrate YP_001052385.1 TIGRFAM: putative AcnD-accessory protein PrpF; PFAM: protein of unknown function DUF453; KEGG: shm:Shewmr7_0312 putative AcnD-accessory protein PrpF YP_001052386.1 KEGG: sil:SPO1470 isocitrate lyase family protein YP_001052387.1 KEGG: shn:Shewana3_3829 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; Two component regulator three Y domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001052388.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001052389.1 PFAM: Modulator of Rho-dependent transcription termination; KEGG: shm:Shewmr7_0308 transcriptional antiterminator, Rof YP_001052390.1 KEGG: son:SO0338 hypothetical protein YP_001052391.1 PFAM: Endoribonuclease L-PSP; KEGG: shn:Shewana3_3834 endoribonuclease L-PSP YP_001052392.1 PFAM: Citrate transporter; Na+/H+ antiporter NhaC; KEGG: shm:Shewmr7_0305 Na+/H+ antiporter NhaC YP_001052393.1 PFAM: protein of unknown function DUF904; KEGG: shm:Shewmr7_0304 protein of unknown function DUF904 YP_001052394.1 PFAM: protein of unknown function DUF1107; KEGG: son:SO0334 hypothetical protein YP_001052395.1 PFAM: DSBA oxidoreductase; KEGG: shm:Shewmr7_0302 DsbA oxidoreductase YP_001052396.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_001052397.1 KEGG: shn:Shewana3_3840 conserved hypothetical protein YP_001052398.1 PFAM: protein of unknown function UPF0061; KEGG: shm:Shewmr7_0299 protein of unknown function UPF0061 YP_001052399.1 KEGG: shn:Shewana3_3842 hypothetical protein YP_001052400.1 KEGG: shn:Shewana3_3843 conserved hypothetical protein YP_001052401.1 PFAM: DsrE family protein; KEGG: shn:Shewana3_3844 DsrE family protein YP_001052402.1 KEGG: shn:Shewana3_3845 conserved hypothetical protein YP_001052403.1 KEGG: shn:Shewana3_3846 conserved hypothetical protein YP_001052404.1 KEGG: shn:Shewana3_3847 conserved hypothetical protein YP_001052406.1 TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis PhzC/PhzF protein; KEGG: efa:EF2208 phenazine biosynthesis protein PhzF family YP_001052407.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: eca:ECA2654 GntR-family transcriptional regulator YP_001052408.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: pol:Bpro_5175 NAD(P)H dehydrogenase (quinone) YP_001052409.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: hch:HCH_03334 thiol-disulfide isomerase and thioredoxins YP_001052410.1 PFAM: cytochrome c biogenesis protein, transmembrane region; KEGG: hch:HCH_03335 thiol:disulfide interchange protein YP_001052411.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pfl:PFL_2190 PhnO-related protein YP_001052412.1 KEGG: shm:Shewmr7_0292 hypothetical protein YP_001052413.1 PFAM: acyltransferase 3; KEGG: she:Shewmr4_3653 acyltransferase 3 YP_001052414.1 KEGG: shn:Shewana3_3866 conserved hypothetical protein YP_001052415.1 PFAM: protein of unknown function DUF1232; KEGG: shn:Shewana3_3867 protein of unknown function DUF1232 YP_001052416.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: shm:Shewmr7_0281 transcriptional regulator, AraC family YP_001052417.1 PFAM: PEBP family protein; KEGG: she:Shewmr4_3665 YbhB and YbcL YP_001052418.1 KEGG: shn:Shewana3_3870 conserved hypothetical protein YP_001052419.1 PFAM: Orn/Lys/Arg decarboxylase, major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: she:Shewmr4_3667 ornithine decarboxylase YP_001052420.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system YP_001052421.1 PFAM: porin, Gram-negative type; KEGG: shn:Shewana3_3873 porin, gram-negative type YP_001052422.1 KEGG: msu:MS0957 gluconate kinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase YP_001052423.1 TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: pha:PSHAb0479 putative idonate or gluconate permease YP_001052424.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: yps:YPTB3798 gluconate utilization system Gnt-I transcriptional repressor YP_001052425.1 PFAM: Radical SAM domain protein; Radical SAM N-terminal domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: son:SO0311 hypothetical Fe-S oxidoreductase YP_001052426.1 KEGG: shm:Shewmr7_0274 hypothetical protein YP_001052427.1 PFAM: protein of unknown function DUF1212; KEGG: shn:Shewana3_3876 protein of unknown function DUF1212 YP_001052428.1 KEGG: shn:Shewana3_3877 conserved hypothetical protein YP_001052429.1 KEGG: sdn:Sden_0547 hypothetical protein YP_001052430.1 KEGG: sdn:Sden_0546 putative orphan protein YP_001052431.1 KEGG: sdn:Sden_0545 hypothetical protein YP_001052432.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: son:SO0301 hypothetical methyltransferase YP_001052433.1 PFAM: LppC family lipoprotein; KEGG: shm:Shewmr7_0261 LppC family lipoprotein YP_001052434.1 PFAM: protein of unknown function UPF0102; KEGG: shm:Shewmr7_0260 protein of unknown function UPF0102 YP_001052435.1 TIGRFAM: phosphoheptose isomerase; KEGG: shn:Shewana3_3882 phosphoheptose isomerase YP_001052436.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria; KEGG: shn:Shewana3_3883 transport-associated YP_001052437.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: shm:Shewmr7_0257 protein of unknown function DUF6, transmembrane YP_001052438.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shn:Shewana3_3885 transcriptional regulator, LysR family YP_001052439.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001052440.1 KEGG: son:SO0293 phosphoglycolate phosphatase; TIGRFAM: phosphoglycolate phosphatase ; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001052441.1 PFAM: ribulose-phosphate 3-epimerase; Orotidine 5'-phosphate decarboxylase; KEGG: shm:Shewmr7_0253 ribulose-phosphate 3-epimerase YP_001052442.1 KEGG: shm:Shewmr7_0252 hypothetical protein YP_001052443.1 KEGG: son:SO0290 hypothetical protein YP_001052444.1 KEGG: shn:Shewana3_3891 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_001052445.1 PFAM: Sporulation domain protein; KEGG: son:SO0288 DamX domain protein YP_001052446.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001052447.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001052448.1 TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; Secretin/TonB, short N-terminal domain; KEGG: shn:Shewana3_3895 type IV pilus secretin PilQ YP_001052449.1 PFAM: Pilus assembly protein, PilQ; KEGG: shn:Shewana3_3896 methyl-accepting chemotaxis sensory transducer YP_001052450.1 PFAM: Pilus assembly protein, PilO; KEGG: shm:Shewmr7_0244 pilus assembly protein, PilO YP_001052451.1 PFAM: Fimbrial assembly family protein; KEGG: she:Shewmr4_3702 fimbrial assembly family protein YP_001052452.1 TIGRFAM: type IV pilus assembly protein PilM; KEGG: shm:Shewmr7_0242 type IV pilus assembly protein PilM YP_001052453.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; KEGG: shm:Shewmr7_0241 penicillin-binding protein, 1A family YP_001052454.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001052455.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001052456.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001052457.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001052458.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001052459.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001052460.1 PFAM: protein of unknown function DUF1439; KEGG: shn:Shewana3_3907 protein of unknown function DUF1439 YP_001052461.1 TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: son:SO0272 competence/damage-inducible protein CinA YP_001052462.1 PFAM: GCN5-related N-acetyltransferase; KEGG: aha:AHA_0456 acetyltransferase YP_001052463.1 TIGRFAM: DNA binding domain, excisionase family; KEGG: she:Shewmr4_3713 DNA binding domain, excisionase family YP_001052464.1 PFAM: formate dehydrogenase, subunit FdhD; KEGG: she:Shewmr4_3714 formate dehydrogenase, subunit FdhD YP_001052465.1 KEGG: shm:Shewmr7_3786 hypothetical protein YP_001052466.1 KEGG: shn:Shewana3_3912 conserved hypothetical protein YP_001052467.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4506 iron-sulfur cluster-binding protein YP_001052468.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: she:Shewmr4_3718 cytoplasmic chaperone TorD family protein YP_001052469.1 KEGG: shn:Shewana3_3915 hypothetical protein YP_001052470.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: she:Shewmr4_3720 twin-arginine translocation pathway signal YP_001052471.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shn:Shewana3_3917 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001052472.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: shn:Shewana3_3918 formate dehydrogenase, gamma subunit YP_001052473.1 KEGG: shn:Shewana3_3919 hypothetical protein YP_001052474.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: shm:Shewmr7_3795 twin-arginine translocation pathway signal YP_001052475.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shn:Shewana3_3921 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001052476.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: shn:Shewana3_3922 formate dehydrogenase, gamma subunit YP_001052477.1 PFAM: transposase, IS4 family protein; KEGG: son:SO1008 transposase, putative YP_001052478.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001052479.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001052480.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001052481.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001052482.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001052483.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001052484.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001052485.1 late assembly protein YP_001052486.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001052487.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001052488.1 binds 5S rRNA along with protein L5 and L25 YP_001052489.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001052490.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001052491.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001052492.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001052493.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001052494.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001052495.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001052496.1 one of the stabilizing components for the large ribosomal subunit YP_001052497.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001052498.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001052499.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001052500.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001052501.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001052502.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001052503.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001052504.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001052505.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001052506.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001052507.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001052508.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001052509.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001052510.1 PFAM: RNP-1 like RNA-binding protein; KEGG: shm:Shewmr7_0175 RNP-1 like RNA-binding protein YP_001052511.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001052512.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_001052513.1 PFAM: transposase, IS4 family protein; KEGG: son:SO3544 ISSod7, transposase YP_001052514.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_001052515.1 PFAM: fatty acid desaturase; KEGG: son:SO0197 fatty acid desaturase, family 1 YP_001052516.1 catalyzes the formation of selenophosphate from selenide and ATP YP_001052517.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_001052518.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: shm:Shewmr7_0168 phospholipid/glycerol acyltransferase YP_001052519.1 KEGG: shn:Shewana3_0172 transcriptional regulator, TetR family YP_001052520.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_0171 GCN5-related N-acetyltransferase YP_001052521.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: shm:Shewmr7_0165 3'(2'),5'-bisphosphate nucleotidase YP_001052522.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001052523.1 PFAM: OmpA domain protein transmembrane region-containing protein; Fibronectin, type III domain protein; Ig family protein; SMART: LamG domain protein jellyroll fold domain protein; Dystroglycan-type cadherin domain protein; KEGG: son:SO0189 fibronectin type III domain protein YP_001052524.1 PFAM: phage Tail Collar domain protein; KEGG: sdn:Sden_3729 phage tail collar YP_001052525.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_0166 GCN5-related N-acetyltransferase YP_001052526.1 KEGG: shn:Shewana3_0165 conserved hypothetical protein YP_001052527.1 PFAM: Phytanoyl-CoA dioxygenase; KEGG: son:SO0180 hypothetical protein YP_001052528.1 PFAM: Aspartyl/Asparaginyl beta-hydroxylase; Cupin 2, conserved barrel domain protein; KEGG: shn:Shewana3_0163 aspartyl/asparaginyl beta-hydroxylase YP_001052529.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO0177 HAD-superfamily hydrolase, subfamily IA, variant 3 protein family YP_001052530.1 PFAM: type II secretion system protein N; KEGG: shn:Shewana3_0161 type II secretion system protein N YP_001052531.1 PFAM: General secretion pathway M protein; KEGG: shn:Shewana3_0160 general secretion pathway M protein YP_001052532.1 TIGRFAM: general secretion pathway protein L; PFAM: General secretion pathway L; KEGG: shn:Shewana3_0159 general secretion pathway protein L YP_001052533.1 PFAM: General secretion pathway protein K; KEGG: shn:Shewana3_0158 general secretion pathway protein K YP_001052534.1 TIGRFAM: general secretion pathway protein J; KEGG: shm:Shewmr7_0157 general secretion pathway protein J YP_001052535.1 TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: shm:Shewmr7_0156 general secretion pathway protein I YP_001052536.1 TIGRFAM: general secretion pathway protein H; KEGG: son:SO0170 general secretion pathway protein H YP_001052537.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: shn:Shewana3_0154 general secretion pathway protein G YP_001052538.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein; KEGG: shn:Shewana3_0153 general secretion pathway protein F YP_001052539.1 KEGG: she:Shewmr4_0157 general secretory pathway protein E; TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001052540.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: shm:Shewmr7_0151 general secretion pathway protein D YP_001052541.1 TIGRFAM: general secretion pathway protein C; KEGG: she:Shewmr4_0155 general secretion pathway protein C YP_001052542.1 PFAM: RNA-binding S4 domain protein; KEGG: shn:Shewana3_0149 RNA-binding S4 domain protein YP_001052543.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001052544.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001052545.1 PFAM: sodium:dicarboxylate symporter; KEGG: son:SO0157 proton/glutamate symporter YP_001052546.1 KEGG: she:Shewmr4_0146 hypothetical protein YP_001052547.1 PFAM: peptidase M14, carboxypeptidase A; KEGG: she:Shewmr4_0145 peptidase M14, carboxypeptidase A YP_001052548.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_0139 methyltransferase type 11 YP_001052549.1 KEGG: shn:Shewana3_0138 lipoprotein, putative YP_001052550.1 KEGG: ppu:PP_1959 hypothetical protein YP_001052551.1 PFAM: Excinuclease ABC, C subunit domain protein; KEGG: she:Shewmr4_0137 excinuclease ABC, C subunit domain protein YP_001052552.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller; KEGG: shn:Shewana3_0135 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller YP_001052553.1 DHBP synthase; functions during riboflavin biosynthesis YP_001052554.1 KEGG: shn:Shewana3_0133 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) YP_001052555.1 KEGG: shn:Shewana3_0133 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001052556.1 PFAM: Ferritin, Dps family protein; KEGG: shn:Shewana3_0132 ferritin, Dps family protein YP_001052557.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV; KEGG: shm:Shewmr7_0126 molybdenum cofactor synthesis domain YP_001052558.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001052559.1 KEGG: shn:Shewana3_0129 response regulator receiver protein YP_001052560.1 PFAM: protein of unknown function DUF333; KEGG: shn:Shewana3_0128 protein of unknown function DUF333 YP_001052561.1 PFAM: protein of unknown function DUF890; KEGG: shm:Shewmr7_0122 protein of unknown function DUF890 YP_001052562.1 PFAM: flagellar basal body-associated protein FliL; KEGG: son:SO0132 flagellar protein FliL, putative YP_001052563.1 PFAM: Chorismate lyase; KEGG: son:SO0131 putative chorismate--pyruvate lyase YP_001052564.1 PFAM: PKD domain containing protein; peptidase M6, immune inhibitor A; KEGG: shn:Shewana3_0124 peptidase M6, immune inhibitor A YP_001052565.1 PFAM: multiple antibiotic resistance (MarC)-related proteins; KEGG: shn:Shewana3_0123 multiple antibiotic resistance (MarC)-related proteins YP_001052566.1 KEGG: shm:Shewmr7_0117 hypothetical protein YP_001052567.1 PFAM: protein of unknown function DUF833; KEGG: she:Shewmr4_0121 protein of unknown function DUF833 YP_001052568.1 KEGG: shn:Shewana3_0120 conserved hypothetical protein YP_001052569.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: shn:Shewana3_0119 phospholipid/glycerol acyltransferase YP_001052570.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shn:Shewana3_0118 lysine exporter protein (LysE/YggA) YP_001052571.1 PFAM: MscS Mechanosensitive ion channel; KEGG: shn:Shewana3_0117 MscS mechanosensitive ion channel YP_001052572.1 KEGG: son:SO0120 hypothetical protein YP_001052573.1 PFAM: protein of unknown function DUF1090; KEGG: son:SO0119 hypothetical protein YP_001052574.1 KEGG: shn:Shewana3_0115 conserved hypothetical protein YP_001052575.1 PFAM: peptidase M23B; KEGG: sdn:Sden_2622 peptidase M23B YP_001052576.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ppr:PBPRA1918 putative glyoxalase family protein YP_001052577.1 KEGG: shn:Shewana3_0112 conserved hypothetical protein YP_001052578.1 PFAM: peptidase M48, Ste24p; KEGG: son:SO0110 hypothetical protease YP_001052579.1 KEGG: vfi:VF1170 hypothetical protein YP_001052580.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: rso:RS05505 putative transcription regulator protein YP_001052581.1 PFAM: branched-chain amino acid transport; KEGG: rha:RHA1_ro03339 probable branched chain amino acid transport protein YP_001052582.1 PFAM: AzlC family protein; KEGG: rha:RHA1_ro03338 probable branched-chain amino acid transporter YP_001052583.1 PFAM: aminotransferase, class I and II; KEGG: lpf:lpl0212 hypothetical protein YP_001052584.1 KEGG: gvi:glr2602 hypothetical protein YP_001052585.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_001052586.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001052587.1 TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein; KEGG: she:Shewmr4_0098 transcriptional regulator, histidine utilization repressor, GntR family YP_001052588.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_001052589.1 PFAM: Siderophore-interacting protein; FAD-binding 9, siderophore-interacting domain protein; KEGG: shm:Shewmr7_0091 FAD-binding 9, siderophore-interacting domain protein YP_001052590.1 PFAM: regulatory protein, MarR; KEGG: shn:Shewana3_0096 transcriptional regulator, MarR family YP_001052591.1 PFAM: peptidase domain protein; Endonuclease I; KEGG: sdn:Sden_3289 endonuclease I YP_001052593.1 PFAM: Negative transcriptional regulator; KEGG: pat:Patl_2431 negative transcriptional regulator YP_001052594.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: csa:Csal_2061 glycerophosphoryl diester phosphodiesterase YP_001052596.1 KEGG: shn:Shewana3_0091 hypothetical protein YP_001052597.1 KEGG: son:SO0085 hypothetical protein YP_001052598.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO0084 HAD-superfamily hydrolase, subfamily IA, variant 1 family protein YP_001052599.1 KEGG: sdn:Sden_0075 hypothetical protein YP_001052600.1 PFAM: Carboxymuconolactone decarboxylase; KEGG: son:SO0083 carboxymuconolactone decarboxylase family protein YP_001052601.1 PFAM: regulatory protein, MerR; KEGG: son:SO0082 transcriptional regulator, MerR family YP_001052602.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: shn:Shewana3_0088 glutathione-dependent formaldehyde-activating, GFA YP_001052603.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_0081 thioesterase superfamily protein YP_001052604.1 KEGG: vvu:VV2_0321 hypothetical protein YP_001052605.1 PFAM: HPP family protein+B94; KEGG: shn:Shewana3_0083 HPP family protein YP_001052606.1 PFAM: thioesterase superfamily protein; KEGG: shn:Shewana3_0082 thioesterase superfamily protein YP_001052607.1 KEGG: shm:Shewmr7_0077 MORN variant repeat protein YP_001052608.1 PFAM: AMP-dependent synthetase and ligase; KEGG: shm:Shewmr7_0076 AMP-dependent synthetase and ligase YP_001052609.1 KEGG: son:SO0074 hypothetical protein YP_001052610.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: she:Shewmr4_0076 ABC transporter related YP_001052611.1 PFAM: regulatory protein GntR, HTH; KEGG: son:SO0072 transcriptional regulator, GntR family YP_001052612.1 PFAM: alpha/beta hydrolase fold; TAP domain protein; KEGG: shn:Shewana3_0076 TAP domain protein YP_001052613.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0070 ATP-binding transport protein NatA YP_001052614.1 KEGG: son:SO0069 transport protein, putative YP_001052615.1 KEGG: son:SO0068 hypothetical protein YP_001052616.1 TIGRFAM: penicillin-binding protein 1C; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; Penicillin-binding domain protein; KEGG: son:SO0067 penicillin-binding protein 1C, putative YP_001052617.1 PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin domain protein 2; KEGG: son:SO0066 hypothetical protein YP_001052618.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_001052619.1 PFAM: PfkB domain protein; KEGG: she:Shewmr4_0067 PfkB domain protein YP_001052620.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shn:Shewana3_0068 TonB-dependent receptor YP_001052621.1 PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_0065 major facilitator superfamily MFS_1 YP_001052622.1 KEGG: shn:Shewana3_0066 alpha amylase, catalytic region; PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001052623.1 KEGG: shm:Shewmr7_3734 transposase YP_001052624.1 KEGG: shn:Shewana3_0092 integrase, catalytic region YP_001052625.1 PFAM: Integrase, catalytic region; KEGG: sfr:Sfri_4013 integrase, catalytic region YP_001052626.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfr:Sfri_4014 transposase IS3/IS911 family protein YP_001052627.1 PFAM: Integrase, catalytic region; KEGG: shm:Shewmr7_3980 integrase, catalytic region YP_001052628.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein, LacI; KEGG: she:Shewmr4_0063 transcriptional regulator, LacI family YP_001052629.1 PFAM: major facilitator superfamily MFS_1; KEGG: shn:Shewana3_0064 major facilitator superfamily MFS_1 YP_001052630.1 PFAM: NLP/P60 protein; KEGG: shn:Shewana3_0063 NLP/P60 protein YP_001052631.1 PFAM: protein of unknown function DUF81; KEGG: shm:Shewmr7_0058 protein of unknown function DUF81 YP_001052632.1 PFAM: major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_0056 major facilitator superfamily MFS_1 YP_001052633.1 PFAM: response regulator receiver; LytTr DNA-binding region; KEGG: shm:Shewmr7_0055 response regulator receiver protein YP_001052634.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type, transmembrane region; KEGG: shm:Shewmr7_0054 signal transduction histidine kinase, LytS YP_001052635.1 PFAM: Pirin domain protein domain protein; Pirin domain protein; KEGG: shm:Shewmr7_0053 pirin domain protein domain protein YP_001052636.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: shm:Shewmr7_0052 periplasmic sensor signal transduction histidine kinase YP_001052637.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO0059 transcriptional regulatory protein KdpE YP_001052638.1 PFAM: TrkA-N domain protein; KEGG: shn:Shewana3_0058 TrkA-N domain protein YP_001052639.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: she:Shewmr4_0051 potassium uptake protein, TrkH family YP_001052640.1 KEGG: eca:ECA0649 putative DNA mismatch repair protein YP_001052641.1 PFAM: transposase IS3/IS911 family protein; KEGG: son:SOA0146 ISSod1, transposase OrfA YP_001052642.1 KEGG: son:SOA0145 ISSod1, transposase OrfB YP_001052643.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001052644.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001052645.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_3021 integrase, catalytic region YP_001052646.1 KEGG: ppr:PBPRA1823 hypothetical protein YP_001052647.1 PFAM: IS66 Orf2 family protein; KEGG: pha:PSHAa0409 hypothetical protein YP_001052648.1 KEGG: abo:ABO_1505 hypothetical protein YP_001052649.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001052650.1 PFAM: transposase IS3/IS911 family protein; KEGG: sdn:Sden_2169 hypothetical protein YP_001052651.1 KEGG: bca:BCE_0185 Tn7-like transposition protein D YP_001052652.1 KEGG: pfo:Pfl_5723 Tn7-like transposition protein C YP_001052654.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001052655.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001052656.1 KEGG: bca:BCE_0183 Tn7-like transposition protein B YP_001052657.1 KEGG: ava:Ava_3486 Tn7-like transposition protein A YP_001052658.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: shn:Shewana3_0055 HI0933 family protein YP_001052659.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001052660.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001052661.1 PFAM: Rhodanese domain protein; KEGG: shn:Shewana3_0052 rhodanese domain protein YP_001052662.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001052663.1 PFAM: peptidase M23B; KEGG: shn:Shewana3_0050 peptidase M23B YP_001052664.1 KEGG: shn:Shewana3_0049 carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001052665.1 PFAM: protein of unknown function DUF610, YibQ; KEGG: shm:Shewmr7_0040 protein of unknown function DUF610, YibQ YP_001052666.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: she:Shewmr4_0041 transcriptional regulator, BadM/Rrf2 family YP_001052667.1 PFAM: protein of unknown function UPF0153; KEGG: shn:Shewana3_0046 protein of unknown function UPF0153 YP_001052668.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: she:Shewmr4_3916 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001052669.1 KEGG: shn:Shewana3_4122 conserved hypothetical protein YP_001052670.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_001052671.1 KEGG: son:SO4740 hypothetical protein YP_001052672.1 KEGG: tcx:Tcr_0334 type I site-specific deoxyribonuclease, HsdR family YP_001052673.1 PFAM: Integrase, catalytic region; KEGG: mlo:mll6233 transposase YP_001052674.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: eba:ebA270 transposition helper protein YP_001052675.1 KEGG: tcx:Tcr_0334 type I site-specific deoxyribonuclease, HsdR family; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like YP_001052676.1 KEGG: plu:plu4453 hypothetical protein YP_001052677.1 KEGG: plu:plu4452 hypothetical protein; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001052678.1 PFAM: restriction modification system DNA specificity domain; KEGG: net:Neut_0540 restriction modification system DNA specificity domain YP_001052679.1 KEGG: tcx:Tcr_0332 N-6 DNA methylase YP_001052680.1 PFAM: Integrase, catalytic region; KEGG: sdn:Sden_2168 integrase, catalytic region YP_001052681.1 KEGG: aeh:Mlg_2336 hypothetical protein YP_001052682.1 PFAM: N-6 DNA methylase; KEGG: tcx:Tcr_0332 N-6 DNA methylase YP_001052683.1 TIGRFAM: DNA binding domain, excisionase family; KEGG: hch:HCH_10013 predicted transcriptional regulator YP_001052684.1 KEGG: pst:PSPTO_0023 hypothetical protein YP_001052685.1 PFAM: helix-turn-helix domain protein; KEGG: pst:PSPTO_0022 DNA-binding protein YP_001052686.1 KEGG: ilo:IL2609 transposon Tn7 transposition transposition regulatory protein TnsE YP_001052687.1 KEGG: ssn:SSO_3894 transposition protein YP_001052688.1 KEGG: ilo:IL2611 transposon Tn7 transposition protein TnsC YP_001052689.1 PFAM: Integrase, catalytic region; KEGG: ilo:IL2612 transposon Tn7 transposition protein TnsB YP_001052690.1 KEGG: ilo:IL2613 transposon Tn7 transposition protein TnsA YP_001052691.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001052692.1 PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein; KEGG: son:SO4742 transcriptional regulator, DeoR family YP_001052693.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO4743 TonB-dependent receptor, putative YP_001052694.1 KEGG: shn:Shewana3_4128 UDP-N-acetylglucosamine pyrophosphorylase; TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase YP_001052695.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001052696.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001052697.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001052698.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001052699.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001052700.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001052701.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001052702.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001052703.1 PFAM: ATP synthase I chain; KEGG: son:SO4754 ATP synthase protein I YP_001052704.1 TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: shm:Shewmr7_4025 ParB-like partition proteins YP_001052705.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: shn:Shewana3_4139 cobyrinic acid a,c-diamide synthase YP_001052706.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001052707.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001052708.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001052709.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001052710.1 PFAM: 60 kDa inner membrane insertion protein; KEGG: shm:Shewmr7_4032 60 kDa inner membrane insertion protein YP_001052711.1 PFAM: protein of unknown function DUF37; KEGG: son:SO0005 conserved hypothetical protein TIGR00278 YP_001052712.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001052713.1 in Escherichia coli transcription of this gene is enhanced by polyamines