-- dump date 20140620_063846 -- class Genbank::CDS -- table cds_note -- id note YP_001672236.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001672237.1 KEGG: slo:Shew_0002 DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta chain YP_001672238.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001672239.1 KEGG: shw:Sputw3181_0004 DNA gyrase, B subunit; TIGRFAM: DNA gyrase, B subunit; PFAM: DNA gyrase subunit B domain protein; ATP-binding region ATPase domain protein; TOPRIM domain protein; DNA topoisomerase type IIA subunit B region 2 domain protein; SMART: DNA topoisomerase II YP_001672240.1 PFAM: Metal-dependent hydrolase HDOD; KEGG: shw:Sputw3181_0005 putative signal transduction protein YP_001672241.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001672242.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001672243.1 KEGG: slo:Shew_0011 DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase YP_001672244.1 KEGG: slo:Shew_0012 hypothetical protein YP_001672245.1 PFAM: amidohydrolase; WD40 domain protein beta Propeller; KEGG: slo:Shew_0013 amidohydrolase YP_001672247.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_001672248.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: vfi:VF1792 regulatory protein YP_001672249.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ppr:PBPRB1061 hypothetical protein YP_001672250.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001672251.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001672252.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_001672253.1 PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: slo:Shew_0021 protein of unknown function UPF0029 YP_001672254.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: slo:Shew_0022 potassium uptake protein, TrkH family YP_001672255.1 KEGG: slo:Shew_0023 protoporphyrinogen oxidase YP_001672256.1 PFAM: regulatory protein ArsR; KEGG: shw:Sputw3181_0018 regulatory protein, ArsR YP_001672257.1 KEGG: slo:Shew_0025 protoporphyrinogen oxidase YP_001672258.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: slo:Shew_3740 potassium uptake protein, TrkH family YP_001672259.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001672260.1 TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: slo:Shew_3738 sun protein YP_001672261.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: shm:Shewmr7_0026 methionyl-tRNA formyltransferase YP_001672262.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001672263.1 PFAM: Peptidoglycan-binding LysM; KEGG: slo:Shew_3735 peptidoglycan-binding LysM YP_001672264.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: slo:Shew_3734 DNA protecting protein DprA YP_001672265.1 PFAM: protein of unknown function DUF494; KEGG: shw:Sputw3181_0027 protein of unknown function DUF494 YP_001672266.1 PFAM: Peptidase M9A collagenase domain protein; KEGG: slo:Shew_3732 microbial collagenase YP_001672267.1 PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: sbm:Shew185_0031 DNA topoisomerase type IA zn finger domain protein YP_001672268.1 PFAM: SUA5/yciO/yrdC domain; KEGG: sbm:Shew185_0032 SUA5/YciO/YrdC/YwlC family protein YP_001672269.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001672270.1 TIGRFAM: shikimate 5-dehydrogenase; PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding domain protein; KEGG: slo:Shew_3727 shikimate 5-dehydrogenase YP_001672271.1 PFAM: protein of unknown function DUF1488; KEGG: shn:Shewana3_0044 protein of unknown function DUF1488 YP_001672272.1 KEGG: sbm:Shew185_0037 carbonic anhydrase, family 3 YP_001672273.1 PFAM: protein of unknown function UPF0153; KEGG: slo:Shew_3811 protein of unknown function UPF0153 YP_001672274.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: shn:Shewana3_0047 transcriptional regulator, BadM/Rrf2 family YP_001672275.1 PFAM: protein of unknown function DUF610 YibQ; KEGG: sbl:Sbal_4335 protein of unknown function DUF610, YibQ YP_001672276.1 KEGG: slo:Shew_3808 carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: peptidase S41; SMART: PDZ/DHR/GLGF domain protein YP_001672277.1 PFAM: peptidase M23B; KEGG: slo:Shew_3807 peptidase M23B YP_001672278.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001672279.1 PFAM: Rhodanese domain protein; KEGG: slo:Shew_3805 rhodanese domain protein YP_001672280.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001672281.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001672282.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: slo:Shew_3802 HI0933 family protein YP_001672283.1 KEGG: slo:Shew_3799 hypothetical protein YP_001672284.1 KEGG: cps:CPS_1250 conserved hypothetical protein YP_001672285.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cps:CPS_1249 ABC transporter, ATP-binding protein YP_001672286.1 PFAM: ABC-2 type transporter; KEGG: cps:CPS_1248 ABC transporter, permease protein YP_001672287.1 PFAM: NLP/P60 protein; KEGG: sbm:Shew185_0058 NLP/P60 protein YP_001672288.1 KEGG: vpa:VP1357 hypothetical protein YP_001672289.1 KEGG: bth:BT_1162 hypothetical protein YP_001672290.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_001672291.1 KEGG: saz:Sama_0068 molybdenum cofactor biosynthesis protein Mog YP_001672292.1 KEGG: saz:Sama_0068 molybdenum cofactor biosynthesis protein Mog YP_001672293.1 KEGG: saz:Sama_0068 molybdenum cofactor biosynthesis protein Mog YP_001672294.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: sde:Sde_0081 putative methyl-accepting chemotaxis sensory transducer YP_001672295.1 KEGG: slo:Shew_3782 ABC-2 type transporter YP_001672296.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_3781 ABC transporter-related protein YP_001672297.1 PFAM: alpha/beta hydrolase fold; TAP domain protein; KEGG: slo:Shew_3780 TAP domain protein YP_001672298.1 PFAM: AMP-dependent synthetase and ligase; KEGG: slo:Shew_3776 AMP-dependent synthetase and ligase YP_001672299.1 PFAM: thioesterase superfamily protein; KEGG: sfr:Sfri_3970 thioesterase superfamily protein YP_001672300.1 KEGG: son:SO_0079 hypothetical protein YP_001672301.1 PFAM: thioesterase superfamily protein; KEGG: sdn:Sden_0074 thioesterase superfamily YP_001672302.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: spc:Sputcn32_0069 2,3-diketo-5-methylthio-1-phosphopentane phosphatase YP_001672303.1 PFAM: Lytic transglycosylase catalytic; KEGG: ilo:IL0198 membrane-bound lytic murein transglycosylase C YP_001672304.1 SMART: AAA ATPase; KEGG: vpa:VPA0800 hypothetical protein YP_001672305.1 KEGG: vpa:VPA0799 hypothetical protein YP_001672306.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_001672307.1 TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: slo:Shew_3758 transcriptional regulator, histidine utilization repressor, GntR family YP_001672308.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001672309.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_001672310.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cpf:CPF_1379 acetyltransferase, GNAT family YP_001672311.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sal:Sala_2416 transcriptional regulator, LysR family YP_001672312.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: vha:VIBHAR_03649 hypothetical protein YP_001672313.1 PFAM: Na+/H+ antiporter NhaC; KEGG: dde:Dde_2580 Na+/H+ antiporter family protein YP_001672314.1 KEGG: bbr:BB4545 D-cysteine desulfhydrase YP_001672315.1 PFAM: protein of unknown function DUF81; KEGG: btl:BALH_1459 membrane protein YP_001672316.1 KEGG: slo:Shew_3754 hypothetical protein YP_001672317.1 KEGG: vfi:VF1351 hypothetical protein YP_001672318.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: son:SO_A0164 iron-containing alcohol dehydrogenase YP_001672319.1 KEGG: slo:Shew_3753 hypothetical protein YP_001672320.1 PFAM: MscS Mechanosensitive ion channel; KEGG: slo:Shew_3752 MscS mechanosensitive ion channel YP_001672321.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: slo:Shew_3751 lysine exporter protein (LysE/YggA) YP_001672322.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: slo:Shew_3750 phospholipid/glycerol acyltransferase YP_001672323.1 KEGG: slo:Shew_3749 hypothetical protein YP_001672324.1 PFAM: protein of unknown function DUF833; KEGG: slo:Shew_3748 protein of unknown function DUF833 YP_001672325.1 KEGG: slo:Shew_3747 hypothetical protein YP_001672326.1 PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: slo:Shew_3746 multiple antibiotic resistance (MarC)-related protein YP_001672327.1 PFAM: glycoside hydrolase family 37; KEGG: slo:Shew_3745 glycoside hydrolase, family 37 YP_001672328.1 KEGG: sdn:Sden_0093 hypothetical protein YP_001672329.1 PFAM: PKD domain containing protein; peptidase M6 immune inhibitor A; KEGG: slo:Shew_3744 peptidase M6, immune inhibitor A YP_001672330.1 PFAM: Chorismate lyase; KEGG: sbl:Sbal_4229 chorismate lyase YP_001672331.1 PFAM: flagellar basal body-associated protein FliL; KEGG: sfr:Sfri_0049 flagellar basal body-associated protein FliL YP_001672332.1 PFAM: protein of unknown function DUF890; KEGG: slo:Shew_3741 protein of unknown function DUF890 YP_001672333.1 KEGG: slo:Shew_0052 DNA binding domain, excisionase family YP_001672334.1 PFAM: formate dehydrogenase subunit FdhD; KEGG: slo:Shew_0053 formate dehydrogenase, subunit FdhD YP_001672335.1 KEGG: slo:Shew_0054 hypothetical protein YP_001672336.1 KEGG: sbl:Sbal_4132 hypothetical protein YP_001672337.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: slo:Shew_0056 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001672338.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: slo:Shew_0057 cytoplasmic chaperone TorD family protein YP_001672339.1 TIGRFAM: Formate dehydrogenase region TAT target; KEGG: shw:Sputw3181_3870 hypothetical protein YP_001672340.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: slo:Shew_0059 molybdopterin oxidoreductase YP_001672341.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: shw:Sputw3181_3872 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001672342.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: slo:Shew_0061 formate dehydrogenase, gamma subunit YP_001672343.1 TIGRFAM: Formate dehydrogenase region TAT target; KEGG: slo:Shew_0062 hypothetical protein YP_001672344.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: slo:Shew_0063 molybdopterin oxidoreductase YP_001672345.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: slo:Shew_0064 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001672346.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: sbm:Shew185_4112 formate dehydrogenase, gamma subunit YP_001672347.1 TIGRFAM: Formate dehydrogenase region TAT target; KEGG: slo:Shew_0062 hypothetical protein YP_001672348.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: saz:Sama_3609 formate dehydrogenase, alpha subunit YP_001672349.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: saz:Sama_3608 formate dehydrogenase, iron-sulfur subunit YP_001672350.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: sbm:Shew185_4112 formate dehydrogenase, gamma subunit YP_001672351.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001672352.1 PFAM: PfkB domain protein; KEGG: sbl:Sbal_0278 PfkB domain protein YP_001672353.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: she:Shewmr4_0268 diguanylate cyclase YP_001672354.1 PFAM: MOSC domain containing protein; KEGG: shw:Sputw3181_0239 MOSC domain containing protein YP_001672355.1 KEGG: slo:Shew_0084 hypothetical protein YP_001672356.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase; KEGG: slo:Shew_0086 electron-transferring-flavoprotein dehydrogenase YP_001672357.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001672358.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdenum cofactor biosynthesis protein B; PFAM: molybdopterin binding domain; KEGG: slo:Shew_0088 molybdenum cofactor biosynthesis protein B YP_001672359.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001672360.1 TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: shn:Shewana3_0276 molybdopterin converting factor, subunit 1 YP_001672361.1 PFAM: molybdopterin biosynthesis MoaE protein; KEGG: she:Shewmr4_0276 molybdopterin biosynthesis MoaE YP_001672362.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: slo:Shew_0092 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_001672363.1 TIGRFAM: molybdate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_0093 molybdate ABC transporter, inner membrane subunit YP_001672364.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_0094 ABC transporter-related protein YP_001672365.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_0095 conserved hypothetical protein 156 YP_001672366.1 KEGG: shw:Sputw3181_0250 hypothetical protein YP_001672367.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: slo:Shew_0097 two component transcriptional regulator, winged helix family YP_001672368.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: slo:Shew_0098 integral membrane sensor signal transduction histidine kinase YP_001672369.1 TIGRFAM: pseudouridine synthase Rlu family protein, TIGR01621; PFAM: pseudouridine synthase; KEGG: slo:Shew_0099 pseudouridine synthase Rlu family protein, TIGR01621 YP_001672370.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001672371.1 KEGG: sfr:Sfri_3925 hypothetical protein YP_001672372.1 PFAM: glycosyl transferase family 2; KEGG: shm:Shewmr7_3977 glycosyl transferase, family 2 YP_001672373.1 PFAM: SNARE associated Golgi protein; KEGG: shm:Shewmr7_3976 hypothetical protein YP_001672374.1 PFAM: glycosyl transferase family 39; KEGG: shw:Sputw3181_0066 glycosyl transferase, family 39 YP_001672375.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001672376.1 KEGG: shw:Sputw3181_0068 hypothetical protein YP_001672377.1 PFAM: Ig domain protein group 1 domain protein; KEGG: sdn:Sden_2330 Ig-like, group 1 YP_001672378.1 KEGG: vvu:VV1_2522 prophage antirepressor YP_001672379.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001672380.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin binding domain; molybdopterin-guanine dinucleotide biosynthesis MobB region; MoeA domain protein domain I and II; MoeA domain protein domain IV; KEGG: slo:Shew_3687 molybdopterin-guanine dinucleotide biosynthesis protein B YP_001672381.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein A; KEGG: slo:Shew_3686 molybdopterin-guanine dinucleotide biosynthesis protein A YP_001672382.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_3685 ABC transporter-related protein YP_001672383.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_3684 binding-protein-dependent transport systems inner membrane component YP_001672384.1 PFAM: extracellular solute-binding protein family 1; KEGG: slo:Shew_3683 extracellular solute-binding protein, family 1 YP_001672385.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: slo:Shew_3682 two component, sigma54 specific, transcriptional regulator, fis family YP_001672386.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: slo:Shew_3681 integral membrane sensor signal transduction histidine kinase YP_001672387.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_4074 acetyltransferase, GNAT family YP_001672388.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: sbm:Shew185_4313 hypothetical protein YP_001672389.1 PFAM: GLUG domain protein; KEGG: hch:HCH_03195 RTX toxins and related Ca2+-binding protein YP_001672390.1 TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: slo:Shew_3677 isochorismate synthase YP_001672391.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: she:Shewmr4_3867 TonB-dependent receptor, plug YP_001672392.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO_4712 ABC transporter, ATP-binding protein, putative YP_001672393.1 PFAM: cobalt transport protein; KEGG: sbl:Sbal_0091 cobalt transport protein YP_001672394.1 KEGG: slo:Shew_3673 hypothetical protein YP_001672395.1 KEGG: slo:Shew_3672 hypothetical protein YP_001672396.1 KEGG: shm:Shewmr7_3955 hypothetical protein YP_001672397.1 PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: son:SO_4711 HD domain protein YP_001672398.1 PFAM: ThiJ/PfpI domain protein; KEGG: slo:Shew_3669 ThiJ/PfpI domain protein YP_001672399.1 PFAM: conserved hypothetical protein; KEGG: sbm:Shew185_4296 conserved hypothetical protein 698 YP_001672400.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_001672401.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: vha:VIBHAR_02784 hypothetical protein YP_001672402.1 PFAM: YheO domain protein; KEGG: sfr:Sfri_0689 YheO domain protein YP_001672403.1 PFAM: creatinase; peptidase M24; KEGG: pin:Ping_2026 peptidase M24 YP_001672404.1 PFAM: Asp/Glu racemase; KEGG: pin:Ping_2031 Asp/Glu racemase YP_001672405.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: rci:RCIX1169 hypothetical protein YP_001672406.1 KEGG: pin:Ping_2027 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20 YP_001672407.1 KEGG: shw:Sputw3181_0952 hypothetical protein YP_001672408.1 PFAM: major facilitator superfamily MFS_1; KEGG: hch:HCH_03999 nitrate/nitrite transporter YP_001672409.1 PFAM: regulatory protein LuxR; response regulator receiver; Bacterio-opsin activator HTH domain protein; Sigma-70 region 4 type 2; KEGG: pau:PA14_13730 putative nitrate/nitrite response regulator; NarL YP_001672410.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: psa:PST_0892 two-component sensor NarX YP_001672411.1 PFAM: major facilitator superfamily MFS_1; KEGG: hch:HCH_04020 nitrate/nitrite transporter YP_001672412.1 TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: psa:PST_0896 respiratory nitrate reductase alpha chain YP_001672413.1 TIGRFAM: nitrate reductase, beta subunit; KEGG: pap:PSPA7_1235 nitrate reductase, beta subunit YP_001672414.1 TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: Nitrate reductase delta subunit; KEGG: maq:Maqu_3084 nitrate reductase molybdenum cofactor assembly chaperone YP_001672415.1 KEGG: psa:PST_0899 respiratory nitrate reductase gamma chain; TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase gamma subunit YP_001672416.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: psa:PST_0900 probable peptidyl-prolyl cis-trans isomerase, PpiC-type YP_001672417.1 PFAM: HPP family protein?; KEGG: tcx:Tcr_1929 HPP YP_001672418.1 KEGG: psa:PST_3997 ribonucleotide reductase, alpha subunit YP_001672419.1 PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; serine/threonine protein kinase; KEGG: hch:HCH_04002 serine/threonine protein kinase YP_001672420.1 PFAM: major facilitator superfamily MFS_1; KEGG: hch:HCH_04000 nitrate/nitrite transporter YP_001672421.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: ppr:PBPRB1503 hypothetical membrane protein YP_001672422.1 KEGG: pin:Ping_2027 amidohydrolase YP_001672423.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: vha:VIBHAR_05496 hypothetical protein YP_001672424.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: vfi:VF1121 BCCT family transporter YP_001672425.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001672426.1 KEGG: sbl:Sbal_0122 hypothetical protein YP_001672427.1 KEGG: slo:Shew_3658 hypothetical protein YP_001672428.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: slo:Shew_3657 oligopeptidase A YP_001672429.1 KEGG: shm:Shewmr7_3934 hypothetical protein YP_001672430.1 PFAM: Glutathione S-transferase domain; KEGG: shw:Sputw3181_3976 glutathione S-transferase, N-terminal domain YP_001672431.1 KEGG: shn:Shewana3_4048 conserved hypothetical 3-methyladenine DNA glycosylase YP_001672432.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_0031 efflux transporter, RND family, MFP subunit YP_001672433.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: slo:Shew_0032 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family YP_001672434.1 TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: ypi:YpsIP31758_1434 phosphodiesterase, MJ0936 family YP_001672435.1 PFAM: permease; KEGG: mbb:BCG_2984 putative integral membrane protein YP_001672436.1 PFAM: AbgT putative transporter; KEGG: slo:Shew_3654 AbgT putative transporter YP_001672437.1 PFAM: AbgT putative transporter; short chain fatty acid transporter; KEGG: slo:Shew_3654 AbgT putative transporter YP_001672438.1 PFAM: LemA family protein; KEGG: slo:Shew_3652 LemA family protein YP_001672439.1 KEGG: slo:Shew_3651 hypothetical protein YP_001672440.1 PFAM: Lytic transglycosylase catalytic; KEGG: shw:Sputw3181_3969 lytic transglycosylase, catalytic YP_001672441.1 sodium/drug antiporter; functions as a Na(+)-driven Na(+)/drug antiporter; member of multidrug and toxic compound extrusion (MATE) family; extrudes acriflavines and other compounds by utilizing the sodium gradient YP_001672442.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: vfi:VFA0935 transcriptional regulators, LysR family YP_001672443.1 KEGG: sbm:Shew185_4004 hypothetical protein YP_001672444.1 PFAM: protein of unknown function DUF519; KEGG: shm:Shewmr7_3922 protein of unknown function DUF519 YP_001672445.1 PFAM: transcriptional regulator domain protein; KEGG: sbm:Shew185_3867 transcriptional regulator, CadC YP_001672446.1 KEGG: shm:Shewmr7_2576 decaheme cytochrome c MtrF YP_001672447.1 PFAM: protein of unknown function DUF548; KEGG: sfr:Sfri_3857 protein of unknown function DUF548 YP_001672448.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: sfr:Sfri_2763 MgtE intracellular region YP_001672449.1 KEGG: slo:Shew_2682 hypothetical protein YP_001672450.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: slo:Shew_2681 general substrate transporter YP_001672451.1 KEGG: slo:Shew_2680 putative ferredoxin YP_001672452.1 PFAM: monooxygenase FAD-binding; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: slo:Shew_2679 FAD dependent oxidoreductase YP_001672453.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit ; Electron transfer flavoprotein alpha subunit; KEGG: slo:Shew_2678 electron transfer flavoprotein, alpha subunit YP_001672454.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase YP_001672455.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism YP_001672456.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA YP_001672457.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine YP_001672458.1 PFAM: AMP-dependent synthetase and ligase; KEGG: slo:Shew_2673 AMP-dependent synthetase and ligase YP_001672459.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA YP_001672460.1 PFAM: MaoC domain protein dehydratase; KEGG: drm:Dred_0577 MaoC domain protein dehydratase YP_001672461.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities YP_001672462.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: slo:Shew_2671 alpha/beta hydrolase fold-3 domain protein YP_001672463.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_2670 transcriptional regulator, LysR family YP_001672464.1 PFAM: Disulphide bond formation protein DsbB; KEGG: son:SO_3870 disulfide bond formation protein YP_001672465.1 PFAM: DSBA oxidoreductase; KEGG: son:SO_3871 thiol:disulfide interchange protein, DsbA family YP_001672466.1 PFAM: Arylsulfotransferase; KEGG: spt:SPA3941 hypothetical protein YP_001672467.1 KEGG: vfi:VF0719 putative sugar hydrolase YP_001672468.1 PFAM: regulatory protein TetR; KEGG: slo:Shew_0277 transcriptional regulator, TetR family YP_001672469.1 PFAM: Disulphide bond formation protein DsbB; KEGG: son:SO_3870 disulfide bond formation protein YP_001672470.1 PFAM: DSBA oxidoreductase; KEGG: son:SO_3871 thiol:disulfide interchange protein, DsbA family YP_001672471.1 PFAM: Arylsulfotransferase; KEGG: son:SO_3872 arylsulfate sulfotransferase YP_001672472.1 KEGG: son:SO_3873 hypothetical protein YP_001672473.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: son:SO_3874 transcriptional regulator, LysR family YP_001672474.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_001672475.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_001672476.1 TIGRFAM: transcription elongation factor GreB; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: stm:STM3503 transcription elongation factor and transcript cleavage YP_001672477.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; KEGG: slo:Shew_3634 RNA binding S1 domain protein YP_001672478.1 KEGG: saz:Sama_3506 hypothetical protein YP_001672479.1 KEGG: sbm:Shew185_4199 BioH protein; TIGRFAM: bioH protein; PFAM: alpha/beta hydrolase fold YP_001672480.1 KEGG: shw:Sputw3181_0113 competence protein ComF YP_001672481.1 PFAM: peptidase M14 carboxypeptidase A; KEGG: slo:Shew_0105 peptidase M14, carboxypeptidase A YP_001672482.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_001672483.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: sbl:Sbal_0144 MATE efflux family protein YP_001672484.1 PFAM: polysaccharide deacetylase; KEGG: sbl:Sbal_0145 polysaccharide deacetylase YP_001672485.1 PFAM: electron transport protein SCO1/SenC; KEGG: slo:Shew_0116 electron transport protein SCO1/SenC YP_001672486.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001672487.1 PFAM: cytochrome oxidase assembly; KEGG: sdn:Sden_3523 cytochrome oxidase assembly YP_001672488.1 KEGG: slo:Shew_0119 hypothetical protein YP_001672489.1 KEGG: shw:Sputw3181_0129 hypothetical protein YP_001672490.1 PFAM: cytochrome c oxidase subunit III; KEGG: slo:Shew_0122 cytochrome c oxidase, subunit III YP_001672491.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_001672492.1 KEGG: shn:Shewana3_3992 cytochrome c oxidase, subunit I; TIGRFAM: Cytochrome c oxidase subunit I type; PFAM: cytochrome c oxidase subunit I YP_001672493.1 KEGG: slo:Shew_0125 cytochrome c oxidase, subunit II; TIGRFAM: Cytochrome c oxidase subunit II; PFAM: cytochrome c oxidase subunit II; cytochrome c class I; cytochrome C oxidase subunit II transmembrane region YP_001672494.1 KEGG: son:SO_4604 hypothetical protein YP_001672495.1 Represses a number of genes involved in the response to DNA damage YP_001672496.1 TIGRFAM: FGGY-family pentulose kinase; PFAM: carbohydrate kinase FGGY; KEGG: ppr:PBPRB0722 putative carbohydrate kinase YP_001672497.1 PFAM: inner-membrane translocator; KEGG: ppr:PBPRB0721 putative ABC transporter, permease protein YP_001672498.1 PFAM: inner-membrane translocator; KEGG: ppr:PBPRB0720 putative permease of ABC transporter YP_001672499.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ppr:PBPRB0719 putative ATP-binding protein of ABCtransporter YP_001672500.1 KEGG: ppr:PBPRB0718 putative periplasmic binding protein YP_001672501.1 KEGG: vfi:VF1104 hypothetical protein YP_001672502.1 PFAM: protein of unknown function DUF214; KEGG: slo:Shew_2660 protein of unknown function DUF214 YP_001672503.1 PFAM: protein of unknown function DUF214; KEGG: slo:Shew_2659 protein of unknown function DUF214 YP_001672504.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cps:CPS_5040 ABC transporter, ATP-binding protein YP_001672505.1 KEGG: cps:CPS_5039 hypothetical protein YP_001672506.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_001672507.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; KEGG: slo:Shew_3531 aromatic amino acid transporter YP_001672508.1 SMART: helix-turn-helix- domain containing protein AraC type; KEGG: ppr:PBPRB1682 hypothetical AraC-type transcriptional regulator YP_001672509.1 KEGG: ppr:PBPRB1681 putative permease of the major facilitator superfamily YP_001672510.1 PFAM: secretion protein HlyD family protein; KEGG: ppr:PBPRB1680 putative multidrug resistance efflux pump YP_001672511.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sdn:Sden_0245 GGDEF domain YP_001672512.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sdn:Sden_3512 glyoxalase/bleomycin resistance protein/dioxygenase YP_001672513.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: sfr:Sfri_0266 heavy metal efflux pump, CzcA family protein YP_001672514.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: sfr:Sfri_0267 efflux transporter, RND family, MFP subunit YP_001672515.1 KEGG: slo:Shew_3536 hypothetical protein YP_001672516.1 KEGG: slo:Shew_3537 hypothetical protein YP_001672517.1 KEGG: sfr:Sfri_0591 hypothetical protein YP_001672518.1 KEGG: slo:Shew_3539 hypothetical protein YP_001672519.1 PFAM: NapC/NirT cytochrome c domain protein; KEGG: slo:Shew_3540 NapC/NirT cytochrome c domain protein YP_001672520.1 PFAM: protein of unknown function DUF1145; KEGG: spc:Sputcn32_0287 protein of unknown function DUF1145 YP_001672521.1 TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein; KEGG: shm:Shewmr7_3848 putative methyltransferase YP_001672522.1 KEGG: sbm:Shew185_4164 signal recognition particle-docking protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase YP_001672523.1 KEGG: slo:Shew_3605 cell division ATP-binding protein FtsE; TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: AAA ATPase YP_001672524.1 PFAM: protein of unknown function DUF214; KEGG: slo:Shew_3604 protein of unknown function DUF214 YP_001672525.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001672526.1 KEGG: ppr:PBPRA1981 hypothetical protein YP_001672527.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; Proprotein convertase P; KEGG: vha:VIBHAR_05576 hypothetical protein YP_001672528.1 KEGG: vha:VIBHAR_05575 hypothetical protein YP_001672529.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: shn:Shewana3_3968 O-succinylbenzoate-CoA ligase YP_001672530.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_001672531.1 PFAM: alpha/beta hydrolase fold; KEGG: she:Shewmr4_3768 alpha/beta hydrolase fold YP_001672532.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_001672533.1 PFAM: regulatory protein LysR; KEGG: saz:Sama_2899 transcriptional regulator-like protein YP_001672534.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: shn:Shewana3_3964 transcriptional regulator, LysR family YP_001672535.1 KEGG: slo:Shew_3155 hypothetical protein YP_001672536.1 KEGG: saz:Sama_2902 hypothetical protein YP_001672537.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: she:Shewmr4_3763 twin-arginine translocation pathway signal YP_001672538.1 PFAM: Polysulphide reductase NrfD; KEGG: shw:Sputw3181_3893 polysulphide reductase, NrfD YP_001672539.1 KEGG: shw:Sputw3181_2184 hypothetical protein YP_001672540.1 PFAM: protein of unknown function DUF1332; KEGG: shw:Sputw3181_3890 protein of unknown function DUF1332 YP_001672541.1 KEGG: slo:Shew_3594 hypothetical protein YP_001672542.1 KEGG: slo:Shew_3593 hypothetical protein YP_001672543.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: slo:Shew_3592 Sel1 domain protein repeat-containing protein YP_001672544.1 KEGG: slo:Shew_3591 hypothetical protein YP_001672545.1 KEGG: slo:Shew_3590 hypothetical protein YP_001672546.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_3589 transcriptional regulator, LysR family YP_001672547.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: shn:Shewana3_3948 drug resistance transporter, Bcr/CflA subfamily YP_001672548.1 PFAM: DTW domain containing protein; KEGG: sbm:Shew185_4137 DTW domain containing protein YP_001672549.1 KEGG: sbl:Sbal_0199 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001672550.1 KEGG: slo:Shew_3584 hypothetical protein YP_001672551.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: slo:Shew_3583 methyltransferase type 12 YP_001672552.1 KEGG: bfs:BF1302 hypothetical protein YP_001672553.1 PFAM: type IV pilus assembly PilZ; KEGG: slo:Shew_3582 hypothetical protein YP_001672554.1 PFAM: peptidase M16 domain protein; KEGG: slo:Shew_3581 peptidase M16 domain protein YP_001672555.1 PFAM: peptidase M16 domain protein; KEGG: she:Shewmr4_3741 peptidase M16 domain protein YP_001672556.1 TIGRFAM: RNA methyltransferase, TrmH family, group 2; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: sbm:Shew185_4126 RNA methyltransferase, TrmH family, group 2 YP_001672557.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbm:Shew185_2285 transcriptional regulator, LysR family YP_001672559.1 KEGG: esa:ESA_02741 hypothetical protein YP_001672560.1 KEGG: vha:VIBHAR_p08260 hypothetical protein YP_001672561.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Radical SAM domain protein; KEGG: sfr:Sfri_1984 radical SAM domain protein YP_001672562.1 KEGG: sbm:Shew185_2283 hypothetical protein YP_001672563.1 PFAM: aldehyde dehydrogenase; KEGG: shm:Shewmr7_3772 aldehyde dehydrogenase (NAD(+)) YP_001672564.1 TIGRFAM: Quinone oxidoreductase putative YhdH/YhfP; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sbl:Sbal_0250 alcohol dehydrogenase, zinc-binding domain protein YP_001672565.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: vfi:VF0021 transcriptional regulators, LysR family YP_001672566.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: spc:Sputcn32_3536 flavocytochrome c YP_001672567.1 KEGG: spc:Sputcn32_3535 tetraheme cytochrome c YP_001672568.1 KEGG: spc:Sputcn32_3534 hypothetical protein YP_001672569.1 KEGG: sbm:Shew185_2536 hypothetical protein YP_001672570.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: shm:Shewmr7_2226 transcriptional regulator, LysR family YP_001672571.1 PFAM: regulatory protein TetR; KEGG: sbl:Sbal_0259 putative transcriptional regulator, TetR family YP_001672572.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sbl:Sbal_0260 integral membrane sensor signal transduction histidine kinase YP_001672573.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: slo:Shew_3570 two component transcriptional regulator, winged helix family YP_001672574.1 PFAM: protein of unknown function Spy-related; KEGG: slo:Shew_3569 protein of unknown function, Spy-related YP_001672575.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: shm:Shewmr7_3767 cation diffusion facilitator family transporter YP_001672576.1 KEGG: shm:Shewmr7_3764 nitrogen metabolism transcriptional regulator, NtrC, fis family; TIGRFAM: nitrogen regulation protein NR(I); PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001672577.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sbl:Sbal_0267 signal transduction histidine kinase, nitrogen specific, NtrB YP_001672578.1 KEGG: slo:Shew_3559 hypothetical protein YP_001672579.1 KEGG: ppr:PBPRA1243 hypothetical protein YP_001672580.1 PFAM: ThiJ/PfpI domain protein; KEGG: sbm:Shew185_0262 ThiJ/PfpI domain protein YP_001672581.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: shw:Sputw3181_0227 iron-containing alcohol dehydrogenase YP_001672582.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: slo:Shew_3558 transcriptional regulator, AsnC family YP_001672584.1 KEGG: sus:Acid_2127 glycosyl hydrolase, BNR repeat-containing protein YP_001672585.1 PFAM: helix-turn-helix domain protein; KEGG: pat:Patl_1386 transcriptional regulator, XRE family YP_001672587.1 PFAM: sodium:dicarboxylate symporter; KEGG: shm:Shewmr7_3722 sodium:dicarboxylate symporter YP_001672588.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_001672589.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: saz:Sama_3415 virulence regulator BipA YP_001672590.1 PFAM: Disulphide bond formation protein DsbB; KEGG: she:Shewmr4_3658 disulphide bond formation protein DsbB YP_001672591.1 TIGRFAM: pyridoxal kinase; KEGG: vfi:VF2056 pyridoxine kinase YP_001672592.1 KEGG: slo:Shew_3549 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001672593.1 KEGG: sbm:Shew185_0312 hypothetical protein YP_001672594.1 KEGG: slo:Shew_3546 hypothetical protein YP_001672595.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_001672596.1 PFAM: alpha/beta hydrolase fold; KEGG: slo:Shew_3544 alpha/beta hydrolase fold YP_001672597.1 KEGG: sbm:Shew185_0316 hypothetical protein YP_001672598.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001672599.1 PFAM: Rhodanese domain protein; KEGG: she:Shewmr4_0323 rhodanese domain protein YP_001672600.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001672601.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001672602.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: sfr:Sfri_0339 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ YP_001672603.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001672604.1 KEGG: shn:Shewana3_0330 hypothetical protein YP_001672605.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; tryptophan halogenase; KEGG: shm:Shewmr7_3686 monooxygenase, FAD-binding protein YP_001672606.1 KEGG: shw:Sputw3181_0291 hypothetical protein YP_001672607.1 KEGG: slo:Shew_3519 outer membrane lipoprotein carrier protein LolA YP_001672608.1 KEGG: sfr:Sfri_0345 conserved hypothetical 4-hydroxybenzoyl-CoA thioesterase YP_001672609.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: slo:Shew_3517 histidine ammonia-lyase YP_001672610.1 PFAM: glycosyl transferase family 2; lipid A biosynthesis acyltransferase; KEGG: slo:Shew_3516 glycosyl transferase, family 2 YP_001672611.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: shn:Shewana3_0337 thioester dehydrase family protein YP_001672612.1 KEGG: slo:Shew_3514 hypothetical protein YP_001672613.1 KEGG: slo:Shew_3513 hypothetical protein YP_001672614.1 carries the fatty acid chain in fatty acid biosynthesis YP_001672615.1 KEGG: slo:Shew_3511 acyl carrier protein, putative YP_001672616.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: slo:Shew_3510 phospholipid/glycerol acyltransferase YP_001672617.1 KEGG: shm:Shewmr7_3674 hypothetical protein YP_001672618.1 KEGG: slo:Shew_3508 hypothetical protein YP_001672619.1 catalyzes branch migration in Holliday junction intermediates YP_001672620.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: shw:Sputw3181_3775 Na+/Ca+ antiporter, CaCA family YP_001672621.1 PFAM: AMP-dependent synthetase and ligase; KEGG: slo:Shew_3502 AMP-dependent synthetase and ligase YP_001672622.1 specifically modifies tRNA at position G18 YP_001672623.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: slo:Shew_3500 putative endoribonuclease L-PSP YP_001672624.1 KEGG: slo:Shew_3499 (p)ppGpp synthetase I, SpoT/RelA; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; metal-dependent phosphohydrolase HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase HD region YP_001672625.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001672626.1 Essential for recycling GMP and indirectly, cGMP YP_001672627.1 KEGG: slo:Shew_3496 hypothetical protein YP_001672628.1 KEGG: shm:Shewmr7_0332 hypothetical protein YP_001672629.1 PFAM: aminoglycoside phosphotransferase; KEGG: sbm:Shew185_0356 aminoglycoside phosphotransferase YP_001672630.1 PFAM: acetyl-CoA hydrolase/transferase; KEGG: slo:Shew_3493 acetyl-CoA hydrolase/transferase YP_001672631.1 PFAM: protein of unknown function DUF159; KEGG: maq:Maqu_3372 protein of unknown function DUF159 YP_001672632.1 PFAM: amidohydrolase; KEGG: vha:VIBHAR_06184 hypothetical protein YP_001672633.1 PFAM: Pyridoxal-dependent decarboxylase; KEGG: ppr:PBPRB0277 hypothetical amino acid decarboxylase YP_001672634.1 KEGG: ppr:PBPRB1867 hypothetical protein YP_001672635.1 PFAM: permease; KEGG: mbb:BCG_2984 putative integral membrane protein YP_001672636.1 PFAM: ERCC4 domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: spc:Sputcn32_3619 ERCC4 domain protein YP_001672637.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: sfr:Sfri_3126 cytoplasmic chaperone TorD family protein YP_001672638.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: ent:Ent638_1418 anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family YP_001672639.1 KEGG: stm:STM4307 putative anaerobic dimethyl sulfoxide reductase, subunit C YP_001672640.1 TIGRFAM: Dimethylsulfoxide reductase chain B; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: vfi:VFA0081 anaerobic dimethyl sulfoxide reductase chain B YP_001672641.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: spc:Sputcn32_0666 response regulator receiver protein YP_001672642.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: ppr:PBPRB0007 hypothetical histidine kinase YP_001672643.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: rca:Rcas_3855 mandelate racemase/muconate lactonizing protein YP_001672644.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function YP_001672645.1 KEGG: cdf:CD3003 probable carbohydrate hydrolase (N-terminus) YP_001672646.1 PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; KEGG: cdf:CD3002 probable carbohydrate hydrolase YP_001672647.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bur:Bcep18194_C7696 transcriptional regulator, LysR family YP_001672648.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: reu:Reut_B4119 regulatory protein GntR, HTH:GntR, C-terminal YP_001672649.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: dsy:DSY4261 hypothetical protein YP_001672650.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: son:SO_3706 NupC family protein YP_001672651.1 PFAM: purine or other phosphorylase family 1; KEGG: son:SO_3705 5-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase, putative YP_001672652.1 PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: cps:CPS_3374 putative helicase YP_001672653.1 PFAM: HipA domain protein; KEGG: sbm:Shew185_0650 HipA domain protein YP_001672654.1 PFAM: helix-turn-helix domain protein; KEGG: slo:Shew_0478 transcriptional regulator, XRE family YP_001672655.1 PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: slo:Shew_3489 YicC N-terminal domain protein YP_001672656.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001672657.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001672658.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001672659.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; dienelactone hydrolase; KEGG: slo:Shew_3485 peptidase S9, prolyl oligopeptidase active site domain protein YP_001672660.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_001672661.1 catalyzes the formation of dUMP from dUTP YP_001672662.1 KEGG: sfr:Sfri_3829 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein YP_001672663.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001672664.1 required for 70S ribosome assembly YP_001672665.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001672666.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_001672667.1 KEGG: shw:Sputw3181_0369 hypothetical protein YP_001672668.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: shw:Sputw3181_0370 RarD protein, DMT superfamily transporter YP_001672669.1 PFAM: thioesterase superfamily protein; KEGG: son:SO_4242 hypothetical protein YP_001672670.1 KEGG: shw:Sputw3181_0372 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases YP_001672671.1 KEGG: slo:Shew_3473 response regulator receiver protein YP_001672672.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001672673.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001672674.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001672675.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001672676.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: son:SO_4232 long-chain fatty acid transport protein YP_001672677.1 KEGG: slo:Shew_3467 hypothetical protein YP_001672678.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase FGGY; KEGG: slo:Shew_3466 glycerol kinase YP_001672679.1 KEGG: slo:Shew_3465 hypothetical protein YP_001672680.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001672681.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: slo:Shew_3461 S-adenosyl-methyltransferase MraW YP_001672682.1 PFAM: cell division protein FtsL; KEGG: slo:Shew_3460 cell division protein FtsL YP_001672683.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: slo:Shew_3459 peptidoglycan glycosyltransferase YP_001672684.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001672685.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: slo:Shew_3457 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase YP_001672686.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001672687.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001672688.1 TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: slo:Shew_3454 cell division protein FtsW YP_001672689.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001672690.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001672691.1 PFAM: cell division protein FtsQ; Polypeptide-transport-associated domain protein FtsQ-type; KEGG: slo:Shew_3451 polypeptide-transport-associated domain protein, FtsQ-type YP_001672692.1 PFAM: cell division protein FtsA; KEGG: slo:Shew_3450 cell division protein FtsA YP_001672693.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001672694.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001672695.1 KEGG: slo:Shew_3447 hypothetical protein YP_001672696.1 PFAM: peptidase M23B; KEGG: slo:Shew_3446 peptidase M23B YP_001672697.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001672698.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: sbm:Shew185_3948 mutator MutT protein YP_001672699.1 PFAM: protein of unknown function DUF329; KEGG: slo:Shew_3443 protein of unknown function DUF329 YP_001672700.1 PFAM: protein of unknown function DUF1342; KEGG: slo:Shew_3442 protein of unknown function DUF1342 YP_001672701.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001672702.1 PFAM: peptidase A24A prepilin type IV; peptidase A24A domain protein; KEGG: sbm:Shew185_3944 prepilin peptidase YP_001672703.1 PFAM: type II secretion system protein; KEGG: sfr:Sfri_3784 type II secretion system protein YP_001672704.1 TIGRFAM: type IV-A pilus assembly ATPase PilB; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; KEGG: slo:Shew_3438 type IV-A pilus assembly ATPase PilB YP_001672705.1 KEGG: pha:PSHAa0384 prepilin peptidase dependent protein D YP_001672706.1 KEGG: shn:Shewana3_0422 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase YP_001672707.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: slo:Shew_3434 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD YP_001672708.1 involved in regulation of beta-lactamase; putative signaling protein YP_001672709.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_001672710.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001672711.1 KEGG: sfr:Sfri_3776 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001672712.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001672713.1 KEGG: slo:Shew_3428 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAC repeat-containing protein YP_001672714.1 PFAM: Patatin; surface antigen variable number repeat protein; KEGG: she:Shewmr4_0432 patatin YP_001672715.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_001672716.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001672717.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_001672718.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001672719.1 KEGG: slo:Shew_3416 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase HAMP region domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001672720.1 KEGG: shn:Shewana3_0438 hypothetical protein YP_001672721.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001672722.1 involved in de novo purine biosynthesis YP_001672723.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_001672724.1 PFAM: permease; KEGG: slo:Shew_3410 permease YP_001672725.1 PFAM: DSBA oxidoreductase; KEGG: maq:Maqu_3568 DsbA oxidoreductase YP_001672726.1 PFAM: molybdopterin oxidoreductase Fe4S4 region; KEGG: sbm:Shew185_0099 molybdopterin oxidoreductase Fe4s4 region YP_001672727.1 KEGG: sbm:Shew185_0099 molybdopterin oxidoreductase Fe4s4 region; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_001672728.1 TIGRFAM: formate dehydrogenase, beta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Formate dehydrogenase transmembrane domain protein; KEGG: sbm:Shew185_0101 formate dehydrogenase, beta subunit YP_001672729.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: she:Shewmr4_0104 formate dehydrogenase, gamma subunit YP_001672730.1 TIGRFAM: formate dehydrogenase accessory protein FdhE; PFAM: formate dehydrogenase accessory protein; KEGG: son:SO_0104 fdhE protein YP_001672731.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_001672732.1 TIGRFAM: selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 3; KEGG: she:Shewmr4_0107 selenocysteine-specific translation elongation factor YP_001672733.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_001672734.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: sbm:Shew185_0107 protein of unknown function DUF395 YeeE/YedE YP_001672735.1 PFAM: SirA family protein; KEGG: ypi:YpsIP31758_3809 hypothetical protein YP_001672736.1 PFAM: protein of unknown function DUF28; KEGG: slo:Shew_3408 protein of unknown function DUF28 YP_001672737.1 KEGG: slo:Shew_2580 hypothetical protein YP_001672738.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbm:Shew185_3844 transcriptional regulator, LysR family YP_001672739.1 PFAM: secretion protein HlyD family protein; KEGG: sbm:Shew185_3843 secretion protein HlyD family protein YP_001672740.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: shn:Shewana3_0523 drug resistance transporter, EmrB/QacA subfamily YP_001672741.1 PFAM: GCN5-related N-acetyltransferase; KEGG: slo:Shew_3397 GCN5-related N-acetyltransferase YP_001672742.1 KEGG: slo:Shew_3396 hypothetical protein YP_001672743.1 KEGG: sfr:Sfri_3496 hypothetical protein YP_001672744.1 KEGG: sfr:Sfri_3495 phage integrase family protein YP_001672745.1 PFAM: integrase family protein; KEGG: sfr:Sfri_3494 phage integrase family protein YP_001672746.1 KEGG: sfr:Sfri_3493 hypothetical protein YP_001672748.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); KEGG: mms:mma_0801 RNA-directed DNA polymerase YP_001672749.1 KEGG: reu:Reut_A0005 hypothetical protein YP_001672750.1 KEGG: vei:Veis_1180 hypothetical protein YP_001672751.1 KEGG: vei:Veis_1181 RNA-directed DNA polymerase YP_001672752.1 KEGG: aav:Aave_1701 hypothetical protein YP_001672753.1 PFAM: helix-turn-helix domain protein; KEGG: sfr:Sfri_3420 transcriptional regulator, XRE family protein YP_001672754.1 KEGG: sfr:Sfri_3419 hypothetical protein YP_001672755.1 PFAM: helicase domain protein; type III restriction protein res subunit; KEGG: sfr:Sfri_3418 type III restriction enzyme, res subunit YP_001672756.1 KEGG: chu:CHU_0040 ATPase involved in DNA repair YP_001672758.1 KEGG: sun:SUN_0730 hypothetical protein YP_001672759.1 KEGG: plu:plu4347 hypothetical protein YP_001672760.1 KEGG: vvy:VVA0312 hypothetical protein YP_001672761.1 KEGG: lwe:lwe1072 hypothetical protein YP_001672762.1 SMART: Elongator protein 3/MiaB/NifB; KEGG: sbl:Sbal_0486 radical SAM domain protein YP_001672763.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rso:RSc0144 probable transcription regulator protein YP_001672764.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: cps:CPS_0420 transcriptional regulator, LysR family YP_001672765.1 PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: sfr:Sfri_2899 OmpA/MotB domain protein YP_001672766.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sbm:Shew185_0463 MscS mechanosensitive ion channel YP_001672767.1 KEGG: shw:Sputw3181_3632 hypothetical protein YP_001672768.1 PFAM: protein of unknown function DUF465; KEGG: sbm:Shew185_0466 protein of unknown function DUF465 YP_001672769.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_001672770.1 KEGG: slo:Shew_3389 hypothetical protein YP_001672771.1 PFAM: protein of unknown function DUF107; KEGG: shm:Shewmr7_0449 protein of unknown function DUF107 YP_001672772.1 PFAM: band 7 protein; KEGG: slo:Shew_3387 band 7 protein YP_001672773.1 PFAM: band 7 protein; KEGG: slo:Shew_3386 band 7 protein YP_001672774.1 PFAM: NUDIX hydrolase; KEGG: shn:Shewana3_0463 NUDIX hydrolase YP_001672775.1 KEGG: cps:CPS_1933 sensory box/GGDEF/EAL domain protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; SMART: PAS domain containing protein YP_001672776.1 PFAM: Endoribonuclease L-PSP; KEGG: ppr:PBPRB1933 putative translation initiation inhibitor, YjgF family YP_001672777.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_001672778.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_001672779.1 PFAM: putative esterase; KEGG: sfr:Sfri_3395 hydrolase of the alpha/beta superfamily YP_001672780.1 KEGG: slo:Shew_0343 hypothetical protein YP_001672781.1 PFAM: Na+/H+ antiporter NhaC; KEGG: slo:Shew_0344 Na+/H+ antiporter NhaC YP_001672782.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: slo:Shew_0345 redoxin domain protein YP_001672783.1 PFAM: cytochrome C biogenesis protein; KEGG: mms:mma_2804 cytochrome c-type biogenesis protein CycL YP_001672784.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: son:SO_0478 cytochrome c-type biogenesis protein CcmF YP_001672785.1 KEGG: slo:Shew_0348 cytochrome c, putative YP_001672786.1 SMART: Rhodanese domain protein; KEGG: shw:Sputw3181_0578 rhodanese domain protein YP_001672787.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase FKBP-type; KEGG: slo:Shew_0350 peptidylprolyl isomerase, FKBP-type YP_001672788.1 KEGG: shn:Shewana3_0492 formate-dependent nitrite reductase, NrfG protein YP_001672789.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: she:Shewmr4_0492 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001672790.1 PFAM: Polysulphide reductase NrfD; KEGG: slo:Shew_0353 polysulphide reductase, NrfD YP_001672791.1 PFAM: NosL family protein; KEGG: shm:Shewmr7_3536 NosL family protein YP_001672792.1 PFAM: periplasmic copper-binding; SMART: Parallel beta-helix repeat; Carbohydrate-binding and sugar hydrolysis; KEGG: shw:Sputw3181_0582 periplasmic copper-binding YP_001672793.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_0356 ABC transporter-related protein YP_001672794.1 KEGG: slo:Shew_0357 copper ABC transporter, permease protein YP_001672795.1 PFAM: transcriptional regulator domain protein; KEGG: shm:Shewmr7_3532 transcriptional regulator, CadC YP_001672797.1 KEGG: hch:HCH_03398 hypothetical protein YP_001672798.1 KEGG: fnu:FN1049 hypothetical protein YP_001672799.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: cps:CPS_3142 transporter, LysE family YP_001672801.1 KEGG: slo:Shew_0348 cytochrome c, putative YP_001672802.1 SMART: Rhodanese domain protein; KEGG: slo:Shew_0349 rhodanese domain protein YP_001672803.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase FKBP-type; KEGG: slo:Shew_0350 peptidylprolyl isomerase, FKBP-type YP_001672804.1 KEGG: slo:Shew_0351 tetratricopeptide TPR_2 repeat protein YP_001672805.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: she:Shewmr4_0492 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001672806.1 PFAM: Polysulphide reductase NrfD; KEGG: slo:Shew_0353 polysulphide reductase, NrfD YP_001672807.1 PFAM: NosL family protein; KEGG: sbm:Shew185_3871 NosL family protein YP_001672808.1 PFAM: periplasmic copper-binding; SMART: Parallel beta-helix repeat; Carbohydrate-binding and sugar hydrolysis; KEGG: son:SO_0486 copper ABC transporter, periplasmic copper-binding protein YP_001672809.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_0356 ABC transporter-related protein YP_001672810.1 PFAM: ABC-2 type transporter; KEGG: slo:Shew_0357 copper ABC transporter, permease protein YP_001672811.1 PFAM: transcriptional regulator domain protein; KEGG: shn:Shewana3_0499 transcriptional regulator, CadC YP_001672812.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_001672813.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_001672814.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_001672815.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system YP_001672816.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_001672817.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: vco:VC0395_0006 ribose operon repressor YP_001672818.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_001672819.1 TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; KEGG: slo:Shew_0360 UbiD family decarboxylase YP_001672820.1 KEGG: sfr:Sfri_3388 hypothetical protein YP_001672821.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sfr:Sfri_3606 GCN5-related N-acetyltransferase YP_001672822.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cps:CPS_2140 putative lipoprotein YP_001672823.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: ppr:PBPRA2465 putative tyrosine-specific transport protein YP_001672824.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_001672825.1 PFAM: Choloylglycine hydrolase; KEGG: vfi:VFA0241 choloylglycine hydrolase YP_001672826.1 PFAM: DSBA oxidoreductase; KEGG: pha:PSHAb0519 hypothetical protein YP_001672828.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: shw:Sputw3181_0592 short-chain dehydrogenase/reductase SDR YP_001672829.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: vfi:VF2386 biotin carboxyl carrier protein of acetyl-CoA carboxylase YP_001672830.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001672831.1 PFAM: Class I peptide chain release factor; KEGG: shw:Sputw3181_0594 class I peptide chain release factor YP_001672832.1 KEGG: shn:Shewana3_0513 hypothetical protein YP_001672833.1 KEGG: sbl:Sbal_0473 hypothetical protein YP_001672834.1 KEGG: slo:Shew_3359 hypothetical protein YP_001672835.1 KEGG: slo:Shew_3358 outer membrane efflux family protein, putative YP_001672836.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: slo:Shew_3357 efflux transporter, RND family, MFP subunit YP_001672837.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: slo:Shew_3356 heavy metal efflux pump, CzcA family YP_001672838.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_001672839.1 PFAM: conserved hypothetical protein; KEGG: sfr:Sfri_3560 conserved hypothetical protein 22 YP_001672840.1 KEGG: slo:Shew_3350 hypothetical protein YP_001672841.1 KEGG: slo:Shew_3349 ATP-dependent protease La (LON) domain protein, putative YP_001672842.1 PFAM: pseudouridine synthase; KEGG: sbm:Shew185_0433 pseudouridine synthase YP_001672843.1 KEGG: shn:Shewana3_3710 hypothetical protein YP_001672844.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: she:Shewmr4_3531 dTDP-4-dehydrorhamnose reductase YP_001672845.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: slo:Shew_3343 integral membrane sensor signal transduction histidine kinase YP_001672846.1 PFAM: response regulator receiver; helix-turn-helix Fis-type; KEGG: sfr:Sfri_1844 response regulator receiver protein YP_001672847.1 PFAM: sulphate transporter; KEGG: slo:Shew_0508 xanthine/uracil/vitamin C permease YP_001672848.1 KEGG: slo:Shew_0514 cytochrome c, putative YP_001672849.1 KEGG: slo:Shew_0515 hypothetical protein YP_001672850.1 KEGG: shm:Shewmr7_0441 cytochrome c family protein YP_001672851.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: shn:Shewana3_3687 short-chain dehydrogenase/reductase SDR YP_001672852.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: cps:CPS_4936 substrate-binding transcriptional regulator, LysR family YP_001672853.1 KEGG: slo:Shew_0517 putative plasmid transfer protein YP_001672854.1 PFAM: protein of unknown function DUF81; KEGG: shw:Sputw3181_3556 protein of unknown function DUF81 YP_001672855.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_001672856.1 KEGG: she:Shewmr4_3439 O-succinylhomoserine (thiol)-lyase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein YP_001672857.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001672858.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_001672859.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: aha:AHA_3760 glutathione-dependent formaldehyde-activating, GFA YP_001672860.1 KEGG: she:Shewmr4_3430 hypothetical protein YP_001672861.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: she:Shewmr4_3427 protein of unknown function DUF6, transmembrane YP_001672862.1 PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: slo:Shew_0531 DEAD/DEAH box helicase domain protein YP_001672863.1 PFAM: peptidase M28; KEGG: slo:Shew_0532 peptidase M28 YP_001672864.1 KEGG: shm:Shewmr7_0530 hypothetical protein YP_001672865.1 TIGRFAM: excinuclease ABC, A subunit; PFAM: ABC transporter related; KEGG: slo:Shew_0533 excinuclease ABC, A subunit YP_001672866.1 PFAM: major facilitator superfamily MFS_1; KEGG: slo:Shew_0534 major facilitator superfamily MFS_1 YP_001672867.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: shw:Sputw3181_3534 single-strand binding protein YP_001672868.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: ppr:PBPRA1995 putative transcriptional regulator YP_001672869.1 PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: ppr:PBPRA1994 ornithine carbamoyltransferase YP_001672870.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_001672871.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases YP_001672872.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_001672873.1 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_001672874.1 undetermined function YP_001672875.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpc:RPC_0704 pyruvate flavodoxin/ferredoxin oxidoreductase-like YP_001672876.1 KEGG: sfr:Sfri_1916 hypothetical protein YP_001672877.1 KEGG: saz:Sama_3345 hypothetical protein YP_001672878.1 KEGG: dps:DP2311 hypothetical protein YP_001672879.1 PFAM: biotin/lipoyl attachment domain-containing protein; protein of unknown function DUF182; KEGG: ppr:PBPRA1985 putative protein YqeB YP_001672880.1 KEGG: ppr:PBPRA1986 hypothetical protein YP_001672881.1 KEGG: ppr:PBPRA1987 hypotehtical YgfJ YP_001672882.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase YP_001672883.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS YP_001672884.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: ppr:PBPRB1772 hypothetical endoribonuclease L-PSP YP_001672885.1 PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: ppr:PBPRA1941 hypothetical xanthine dehydrogenase YP_001672886.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: ppr:PBPRA1940 hypothetical CoxS, aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs YP_001672887.1 PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: ppr:PBPRA1939 hypothetical dehydrogenase YP_001672888.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001672889.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_001672890.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain YP_001672891.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration YP_001672892.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ppr:PBPRA1931 putative xanthine permease YP_001672893.1 Catalyzes the deamination of guanine YP_001672894.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: ppr:PBPRA1929 putative xanthine/uracil permease YP_001672895.1 KEGG: slo:Shew_3389 hypothetical protein YP_001672896.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: slo:Shew_0809 formate dehydrogenase, alpha subunit YP_001672897.1 KEGG: slo:Shew_3273 hypothetical protein YP_001672898.1 PFAM: Aldose 1-epimerase; KEGG: sbl:Sbal_3729 aldose 1-epimerase YP_001672899.1 TIGRFAM: galactokinase; PFAM: GHMP kinase; GHMP kinase domain protein; KEGG: slo:Shew_3271 galactokinase YP_001672900.1 TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: slo:Shew_3270 SSS sodium solute transporter superfamily YP_001672901.1 PFAM: glycoside hydrolase family 42 domain 5 loop region; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: slo:Shew_3269 beta-galactosidase YP_001672902.1 KEGG: slo:Shew_3268 hypothetical protein YP_001672903.1 PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: slo:Shew_3267 sodium/hydrogen exchanger YP_001672904.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_001672905.1 PFAM: CutA1 divalent ion tolerance protein; KEGG: sbm:Shew185_0637 CutA1 divalent ion tolerance protein YP_001672906.1 PFAM: FxsA cytoplasmic membrane protein; KEGG: slo:Shew_3264 FxsA cytoplasmic membrane protein YP_001672907.1 SMART: serine/threonine protein kinase; KEGG: slo:Shew_3263 serine/threonine protein kinase YP_001672908.1 KEGG: slo:Shew_3262 hypothetical protein YP_001672909.1 catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide YP_001672910.1 PFAM: porin Gram-negative type; KEGG: sfr:Sfri_0503 porin, gram-negative type YP_001672911.1 PFAM: porin Gram-negative type; KEGG: slo:Shew_3252 porin, gram-negative type YP_001672912.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: slo:Shew_3251 UBA/ThiF-type NAD/FAD binding protein YP_001672913.1 KEGG: slo:Shew_3248 hypothetical protein YP_001672914.1 KEGG: saz:Sama_0549 hypothetical protein YP_001672915.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ppr:PBPRA0992 hypothetical transcriptional regulator YP_001672916.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_001672917.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001672918.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ppu:PP_3666 metabolite MFS transporter, MHS family YP_001672919.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ppr:PBPRA0990 hypothetical transporter YP_001672920.1 PFAM: Endoribonuclease L-PSP; KEGG: ppr:PBPRB1772 hypothetical endoribonuclease L-PSP YP_001672921.1 TIGRFAM: ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: vpa:VP2653 ornithine carbamoyltransferase YP_001672922.1 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_001672923.1 catalyzes the degradation of arginine to citruline and ammonia YP_001672924.1 PFAM: amidinotransferase; KEGG: ppr:PBPRA0993 hypothetical amidinotransferase family protein YP_001672925.1 KEGG: shw:Sputw3181_2974 hypothetical protein YP_001672926.1 PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase; KEGG: shw:Sputw3181_2975 aldehyde ferredoxin oxidoreductase YP_001672927.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbm:Shew185_3107 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_001672930.1 PFAM: peptidase M50; KEGG: slo:Shew_3232 peptidase M50 YP_001672931.1 PFAM: protein of unknown function DUF342; KEGG: slo:Shew_3231 protein of unknown function DUF342 YP_001672932.1 PFAM: methyltransferase small; Methyltransferase small domain protein; KEGG: she:Shewmr4_0687 rRNA (guanine-N(2)-)-methyltransferase YP_001672933.1 PFAM: Alkaline phosphatase; KEGG: shn:Shewana3_3446 alkaline phosphatase YP_001672934.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001672935.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001672936.1 PFAM: Endonuclease I; KEGG: slo:Shew_3223 deoxyribonuclease I YP_001672937.1 PFAM: protein of unknown function DUF335 SprT; SMART: protein of unknown function SprT; KEGG: slo:Shew_3222 protein of unknown function DUF335, SprT YP_001672938.1 KEGG: slo:Shew_3221 hypothetical protein YP_001672939.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_3219 transcriptional regulator, LysR family YP_001672940.1 PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: slo:Shew_3218 carbamoyl-phosphate synthase L chain, ATP-binding YP_001672941.1 PFAM: sodium/hydrogen exchanger; KEGG: noc:Noc_0960 sodium/hydrogen exchanger YP_001672942.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: slo:Shew_3215 ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_001672943.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: shn:Shewana3_3435 transcriptional regulator, LysR family YP_001672944.1 KEGG: sdn:Sden_0845 hypothetical protein YP_001672945.1 KEGG: sfr:Sfri_2734 hypothetical protein YP_001672946.1 PFAM: Nitrate reductase cytochrome c-type subunit (NapB); KEGG: slo:Shew_3209 nitrate reductase cytochrome c-type subunit (NapB) YP_001672947.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA YP_001672948.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway YP_001672949.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001672950.1 PFAM: NapD family protein; KEGG: slo:Shew_3205 NapD family protein YP_001672951.1 KEGG: shn:Shewana3_3423 hypothetical protein YP_001672952.1 PFAM: protein of unknown function DUF214; KEGG: sbm:Shew185_0832 protein of unknown function DUF214 YP_001672953.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbm:Shew185_0833 ABC transporter related YP_001672954.1 KEGG: slo:Shew_3200 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001672955.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: saz:Sama_2951 response regulator receiver protein YP_001672956.1 PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: slo:Shew_3198 glycine cleavage T protein (aminomethyl transferase) YP_001672957.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001672958.1 KEGG: slo:Shew_3195 hypothetical protein YP_001672959.1 PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: vfi:VFA0967 nucleoside permease NupC YP_001672960.1 TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: msu:MS1899 purine-nucleoside phosphorylase YP_001672961.1 PFAM: thioesterase superfamily protein; KEGG: slo:Shew_3192 uncharacterized domain 1 protein YP_001672962.1 KEGG: sdn:Sden_3091 hypothetical protein YP_001672963.1 PFAM: Catalase domain protein; KEGG: slo:Shew_3190 catalase YP_001672964.1 PFAM: protein of unknown function UPF0016; KEGG: son:SO_1071 hypothetical protein YP_001672965.1 PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: slo:Shew_3188 aromatic amino acid permease YP_001672966.1 KEGG: sfr:Sfri_0573 hypothetical protein YP_001672967.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: slo:Shew_3180 pseudouridine synthase YP_001672968.1 KEGG: slo:Shew_3179 hypothetical protein YP_001672969.1 PFAM: Na+/H+ antiporter NhaC; KEGG: slo:Shew_3178 Na+/H+ antiporter NhaC YP_001672970.1 KEGG: sbl:Sbal_1340 hypothetical protein YP_001672971.1 KEGG: shw:Sputw3181_3244 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase YP_001672972.1 KEGG: sfr:Sfri_1337 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: Tetratricopeptide domain protein YP_001672973.1 KEGG: sbm:Shew185_1620 porin gram-negative type YP_001672974.1 PFAM: protein of unknown function DUF541; KEGG: shn:Shewana3_3626 protein of unknown function DUF541 YP_001672975.1 KEGG: ter:Tery_4461 cob(II)yrinic acid a,c-diamide reductase; TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase YP_001672976.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_001672977.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: slo:Shew_3144 UDP-N-acetylmuramate YP_001672978.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; KEGG: shm:Shewmr7_0821 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001672979.1 KEGG: slo:Shew_3142 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_001672980.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_3141 ABC transporter-related protein YP_001672981.1 PFAM: ABC-2 type transporter; KEGG: slo:Shew_3140 ABC-2 type transporter YP_001672982.1 KEGG: shn:Shewana3_3410 hypothetical protein YP_001672983.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001672984.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001672985.1 KEGG: shm:Shewmr7_3295 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK YP_001672986.1 KEGG: slo:Shew_3131 poly(A) polymerase; TIGRFAM: poly(A) polymerase; PFAM: Polynucleotide adenylyltransferase region YP_001672987.1 PFAM: glutamyl-tRNA synthetase class Ic; KEGG: son:SO_0873 glutamyl-tRNA synthetase domain protein YP_001672988.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: slo:Shew_3129 transcriptional regulator, TraR/DksA family YP_001672989.1 Regulatory factor involved in maltose metabolism YP_001672990.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_001672991.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shn:Shewana3_0468 putative transcriptional regulator, CadC YP_001672992.1 KEGG: pin:Ping_1759 hypothetical protein YP_001672993.1 TIGRFAM: 2'-5' RNA ligase; PFAM: Phosphoesterase HXTX; KEGG: pin:Ping_1760 2'-5' RNA ligase YP_001672994.1 KEGG: spc:Sputcn32_0655 ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; Helicase ATP-dependent domain protein; SMART: DEAD-like helicases YP_001672995.1 KEGG: slo:Shew_3123 penicillin-binding protein 1B; TIGRFAM: penicillin-binding protein 1B; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase YP_001672996.1 KEGG: sdn:Sden_0673 hypothetical protein YP_001672997.1 PFAM: major facilitator superfamily MFS_1; KEGG: pap:PSPA7_0980 probable MFS transporter YP_001672998.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdn:Sden_1378 GCN5-related N-acetyltransferase YP_001673000.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: shm:Shewmr7_3399 TonB-dependent receptor YP_001673001.1 KEGG: shn:Shewana3_0631 hypothetical protein YP_001673002.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: slo:Shew_0496 amino acid carrier protein YP_001673004.1 KEGG: slo:Shew_3118 hypothetical protein YP_001673005.1 KEGG: sfr:Sfri_0526 hypothetical protein YP_001673006.1 KEGG: shm:Shewmr7_3380 hypothetical protein YP_001673007.1 PFAM: sodium:dicarboxylate symporter; KEGG: slo:Shew_3115 sodium:dicarboxylate symporter YP_001673008.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: sfr:Sfri_3688 two component, sigma54 specific, transcriptional regulator, fis family protein YP_001673009.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: extracellular solute-binding protein family 3; KEGG: slo:Shew_3113 histidine kinase YP_001673010.1 KEGG: slo:Shew_3112 flavocytochrome c; TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001673011.1 PFAM: protein of unknown function DUF1568; KEGG: sdn:Sden_0135 protein of unknown function DUF1568 YP_001673012.1 PFAM: basic membrane lipoprotein; KEGG: pin:Ping_1297 basic membrane lipoprotein YP_001673013.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pin:Ping_1298 ABC transporter ATP-binding protein YP_001673014.1 PFAM: inner-membrane translocator; KEGG: pin:Ping_1299 ABC transporter inner-membrane translocator YP_001673015.1 PFAM: inner-membrane translocator; KEGG: pin:Ping_1300 ABC sugar transporter inner membrane translocator YP_001673016.1 KEGG: sde:Sde_2333 hypothetical protein YP_001673017.1 KEGG: vpa:VP1852 hypothetical protein YP_001673018.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001673019.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9B dipeptidylpeptidase IV domain protein; KEGG: slo:Shew_0774 peptidase S9B, dipeptidylpeptidase IV domain protein YP_001673020.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: slo:Shew_0777 two component transcriptional regulator, winged helix family YP_001673021.1 KEGG: slo:Shew_0778 hypothetical protein YP_001673022.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_001673023.1 PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: she:Shewmr4_0654 succinylglutamate desuccinylase/aspartoacylase YP_001673024.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_001673025.1 PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_0827 pseudouridylate synthase YP_001673026.1 KEGG: sbm:Shew185_3502 hypothetical protein YP_001673027.1 PFAM: Tellurite resistance protein TehB; Methyltransferase type 11; Methyltransferase type 12; KEGG: shn:Shewana3_3316 methyltransferase type 12 YP_001673028.1 KEGG: slo:Shew_0786 hypothetical protein YP_001673029.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: slo:Shew_0787 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001673030.1 PFAM: dienelactone hydrolase; KEGG: sfr:Sfri_0519 dienelactone hydrolase YP_001673031.1 KEGG: she:Shewmr4_0805 hypothetical protein YP_001673032.1 KEGG: slo:Shew_0791 spermine synthase YP_001673033.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sfr:Sfri_0522 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_001673034.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: slo:Shew_0793 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001673035.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: slo:Shew_0794 diguanylate cyclase YP_001673036.1 KEGG: slo:Shew_0796 hypothetical protein YP_001673037.1 KEGG: slo:Shew_0797 hypothetical protein YP_001673038.1 KEGG: slo:Shew_0798 hypothetical protein YP_001673039.1 PFAM: FAD dependent oxidoreductase; KEGG: sbm:Shew185_3497 FAD dependent oxidoreductase YP_001673040.1 TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter; KEGG: sdn:Sden_3160 chromate transporter YP_001673041.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: slo:Shew_0809 formate dehydrogenase, alpha subunit YP_001673042.1 PFAM: pentapeptide repeat protein; Ion transport 2 domain protein; KEGG: slo:Shew_0810 ion transport 2 domain protein YP_001673043.1 TIGRFAM: peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein; KEGG: slo:Shew_0811 peptide chain release factor 2 YP_001673044.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001673045.1 KEGG: slo:Shew_0813 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001673046.1 PFAM: pseudouridine synthase; KEGG: cps:CPS_1154 RNA pseudouridine synthase family protein YP_001673047.1 TIGRFAM: glucosamine-6-phosphate isomerase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: slo:Shew_0815 glucosamine-6-phosphate isomerase YP_001673048.1 PFAM: nitroreductase; KEGG: sfr:Sfri_3203 nitroreductase YP_001673049.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: mbu:Mbur_1476 cupin family protein YP_001673050.1 PFAM: peptidase U32; KEGG: sbl:Sbal_0734 peptidase U32 YP_001673051.1 PFAM: protein of unknown function DUF1696; KEGG: slo:Shew_0819 protein of unknown function DUF1696 YP_001673052.1 PFAM: Fe-S metabolism associated SufE; KEGG: shn:Shewana3_0807 Fe-S metabolism associated SufE YP_001673053.1 TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; KEGG: son:SO_3789 aminotransferase, class V YP_001673054.1 PFAM: aldo/keto reductase; KEGG: slo:Shew_0736 aldo/keto reductase YP_001673055.1 PFAM: GCN5-related N-acetyltransferase; regulatory protein MarR; KEGG: slo:Shew_0737 transcriptional regulator, MarR family with acetyltransferase activity YP_001673056.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_001673057.1 PFAM: aromatic amino acid permease; KEGG: shn:Shewana3_3365 serine transporter, putative YP_001673058.1 KEGG: slo:Shew_0740 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001673059.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shw:Sputw3181_3313 GCN5-related N-acetyltransferase YP_001673060.1 KEGG: sbm:Shew185_3550 hypothetical protein YP_001673061.1 PFAM: sodium:dicarboxylate symporter; KEGG: slo:Shew_0743 sodium:dicarboxylate symporter YP_001673062.1 PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: spc:Sputcn32_0864 protein of unknown function DUF306, MetA and HslJ YP_001673063.1 KEGG: shn:Shewana3_3360 hypothetical protein YP_001673064.1 KEGG: slo:Shew_0746 diguanylate cyclase YP_001673065.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sbm:Shew185_3545 acetyltransferase, GNAT family YP_001673066.1 KEGG: sfr:Sfri_0644 hypothetical protein YP_001673068.1 KEGG: shm:Shewmr7_3476 hypothetical protein YP_001673069.1 KEGG: mmw:Mmwyl1_2727 hypothetical protein YP_001673070.1 PFAM: protein of unknown function DUF955; KEGG: psb:Psyr_2659 protein of unknown function DUF955 YP_001673071.1 KEGG: slo:Shew_3061 hypothetical protein YP_001673072.1 KEGG: slo:Shew_3061 hypothetical protein YP_001673073.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sfr:Sfri_0645 GCN5-related N-acetyltransferase YP_001673074.1 PFAM: regulatory protein LuxR; Bacterio-opsin activator HTH domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: bam:Bamb_1916 transcriptional regulator, LuxR family YP_001673075.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: ajs:Ajs_3486 fumarate reductase/succinate dehydrogenase flavoprotein domain protein YP_001673076.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: rfr:Rfer_3509 thiamine pyrophosphate enzyme-like TPP binding protein YP_001673077.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001673078.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001673079.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_001673080.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001673081.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_001673082.1 PFAM: protein of unknown function DUF481; KEGG: saz:Sama_2754 hypothetical protein YP_001673083.1 KEGG: she:Shewmr4_0779 response regulator receiver protein YP_001673085.1 KEGG: slo:Shew_0762 hypothetical protein YP_001673086.1 TIGRFAM: PAS sensor protein; PFAM: PAS fold-4 domain protein; KEGG: slo:Shew_0763 putative PAS/PAC sensor protein YP_001673087.1 PFAM: Radical SAM domain protein; KEGG: slo:Shew_0764 radical SAM domain protein YP_001673088.1 PFAM: acriflavin resistance protein; KEGG: sbm:Shew185_3529 acriflavin resistance protein YP_001673089.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_0766 efflux transporter, RND family, MFP subunit YP_001673091.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_001673092.1 PFAM: methyltransferase small; Methyltransferase type 11; Methyltransferase type 12; KEGG: slo:Shew_0768 methyltransferase small YP_001673093.1 PFAM: branched-chain amino acid transport system II carrier protein; KEGG: slo:Shew_0769 branched-chain amino acid transport system II carrier protein YP_001673094.1 TIGRFAM: tyrosine recombinase XerD; PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: sbm:Shew185_3524 tyrosine recombinase XerD YP_001673095.1 KEGG: son:SO_0951 thiol:disulfide interchange protein DsbC YP_001673096.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: slo:Shew_0772 single-stranded-DNA-specific exonuclease RecJ YP_001673097.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: ppr:PBPRA0970 putative transcriptional regulator, AsnC family YP_001673098.1 PFAM: protein of unknown function DUF1063; KEGG: ppr:PBPRB0240 hypothetical inner membrane protein YP_001673099.1 KEGG: vfi:VF0643 serine transporter YP_001673101.1 PFAM: FAD dependent oxidoreductase; KEGG: rba:RB5278 D-amino acid dehydrogenase, small chain YP_001673102.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: hch:HCH_00069 transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain YP_001673103.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: ppu:PP_3565 transporter, LysE family YP_001673104.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001673105.1 PFAM: protein of unknown function DUF808; KEGG: shm:Shewmr7_1013 protein of unknown function DUF808 YP_001673106.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: pha:PSHAa1702 hypothetical protein YP_001673107.1 PFAM: MORN variant repeat protein; KEGG: fnu:FN0738 hypothetical exported 24-amino acid repeat protein YP_001673108.1 KEGG: shn:Shewana3_3482 alkaline phosphatase YP_001673109.1 PFAM: phosphoribosyltransferase; KEGG: slo:Shew_0833 hypoxanthine-guanine phosphoribosyltransferase YP_001673110.1 KEGG: slo:Shew_0834 hypothetical protein YP_001673111.1 TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: son:SO_1059 aminopeptidase N YP_001673112.1 TIGRFAM: membrane lipoprotein lipid attachment site; KEGG: shn:Shewana3_0898 conserved hypothetical protein YP_001673113.1 PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: sbm:Shew185_3477 tetratricopeptide TPR_2 repeat protein YP_001673114.1 PFAM: SlyX family protein; KEGG: slo:Shew_0838 SlyX family protein YP_001673115.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase FKBP-type; KEGG: slo:Shew_0840 peptidylprolyl isomerase, FKBP-type YP_001673116.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: slo:Shew_2784 phosphoesterase, PA-phosphatase related YP_001673117.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_0841 uncharacterized conserved protein UCP006287 YP_001673118.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: slo:Shew_0842 two component transcriptional regulator, LuxR family YP_001673119.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: slo:Shew_0843 signal transduction histidine kinase, nitrate/nitrite-specific, NarQ YP_001673120.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_001673121.1 PFAM: isochorismatase hydrolase; KEGG: shw:Sputw3181_0699 isochorismatase hydrolase YP_001673122.1 PFAM: nitrogen regulatory protein P-II; KEGG: sdn:Sden_2905 nitrogen regulatory protein P-II YP_001673123.1 PFAM: Rh family protein/ammonium transporter; KEGG: sfr:Sfri_0624 Rh family protein/ammonium transporter YP_001673124.1 KEGG: slo:Shew_0848 hypothetical protein YP_001673125.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: slo:Shew_0849 TPR repeat-containing protein YP_001673126.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001673127.1 KEGG: shn:Shewana3_3527 hypothetical protein YP_001673128.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_0853 ABC transporter-related protein YP_001673129.1 KEGG: sbm:Shew185_3700 hypothetical protein YP_001673130.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: shw:Sputw3181_0711 oxidoreductase FAD/NAD(P)-binding domain protein YP_001673131.1 PFAM: extracellular solute-binding protein family 1; KEGG: slo:Shew_0861 extracellular solute-binding protein, family 1 YP_001673132.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfr:Sfri_0637 binding-protein-dependent transport systems inner membrane component YP_001673133.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sbl:Sbal_0603 ABC transporter related YP_001673134.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: slo:Shew_0864 Dyp-type peroxidase family YP_001673135.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: slo:Shew_0865 cupin 2, conserved barrel domain protein YP_001673136.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_001673137.1 oxidizes malate to oxaloacetate YP_001673138.1 PFAM: Polyprenyl synthetase; KEGG: slo:Shew_0868 trans-hexaprenyltranstransferase YP_001673139.1 PFAM: ribosomal protein L21; KEGG: slo:Shew_0869 ribosomal protein L21 YP_001673140.1 involved in the peptidyltransferase reaction during translation YP_001673141.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001673142.1 PFAM: protein of unknown function DUF1212; KEGG: slo:Shew_0872 protein of unknown function DUF1212 YP_001673143.1 KEGG: sbm:Shew185_1040 hypothetical protein YP_001673144.1 PFAM: dihydrofolate reductase region; KEGG: she:Shewmr4_0900 dihydrofolate reductase YP_001673145.1 KEGG: sfr:Sfri_3083 hypothetical protein YP_001673146.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: slo:Shew_0876 methyl-accepting chemotaxis sensory transducer YP_001673147.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_001673148.1 protein associated with Co2+ and Mg2+ efflux YP_001673149.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001673150.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001673151.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: sbm:Shew185_1048 SurA domain protein YP_001673152.1 PFAM: OstA family protein; Organic solvent tolerance protein; KEGG: slo:Shew_0882 organic solvent tolerance protein YP_001673153.1 PFAM: aminoglycoside phosphotransferase; KEGG: shm:Shewmr7_3111 aminoglycoside phosphotransferase YP_001673154.1 PFAM: Nucleotidyl transferase; KEGG: shn:Shewana3_3204 nucleotidyl transferase YP_001673155.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_001673156.1 KEGG: slo:Shew_0886 hypothetical protein YP_001673157.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: shm:Shewmr7_3107 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein YP_001673158.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001673159.1 KEGG: slo:Shew_0889 hypothetical protein YP_001673160.1 PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_0890 secretion protein HlyD family protein YP_001673161.1 PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: slo:Shew_0892 AAA ATPase, central domain protein YP_001673162.1 KEGG: sbm:Shew185_1068 hypothetical protein YP_001673163.1 PFAM: protein of unknown function DUF1289; KEGG: slo:Shew_0894 protein of unknown function DUF1289 YP_001673164.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: shn:Shewana3_3185 ATP-binding region, ATPase domain protein domain protein YP_001673165.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: slo:Shew_0896 two component transcriptional regulator, winged helix family YP_001673166.1 KEGG: slo:Shew_0897 hypothetical protein YP_001673167.1 PFAM: MltA-interacting MipA family protein; KEGG: slo:Shew_0898 MltA-interacting MipA family protein YP_001673168.1 PFAM: GCN5-related N-acetyltransferase; KEGG: saz:Sama_2792 conserved hypothetical acetyltransferase YP_001673169.1 KEGG: shm:Shewmr7_3082 hypothetical protein YP_001673170.1 PFAM: Protein of unknown function DUF1971; KEGG: sbm:Shew185_1077 protein of unknown function DUF1971 YP_001673171.1 KEGG: shm:Shewmr7_1169 UspA domain protein YP_001673172.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: slo:Shew_0913 glyoxalase/bleomycin resistance protein/dioxygenase YP_001673173.1 PFAM: NADPH-dependent FMN reductase; KEGG: slo:Shew_0914 NADPH-dependent FMN reductase YP_001673174.1 PFAM: Helix-turn-helix type 11 domain protein; KEGG: cps:CPS_0091 hypothetical protein YP_001673175.1 PFAM: pseudouridine synthase; KEGG: shw:Sputw3181_3146 pseudouridine synthase YP_001673176.1 PFAM: GPR1/FUN34/yaaH family protein; KEGG: vpa:VP0620 hypothetical protein YP_001673177.1 PFAM: major facilitator superfamily MFS_1; KEGG: slo:Shew_0920 major facilitator superfamily MFS_1 YP_001673178.1 PFAM: LrgB family protein; KEGG: son:SO_1048 hypothetical protein YP_001673179.1 PFAM: LrgA family protein; KEGG: shn:Shewana3_0885 LrgA family protein YP_001673180.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: son:SO_1046 transcriptional regulator, LysR family YP_001673181.1 PFAM: protein of unknown function UPF0057; KEGG: slo:Shew_0100 protein of unknown function UPF0057 YP_001673182.1 PFAM: AMMECR1 domain protein; KEGG: ppr:PBPRA1250 hypothetical protein YP_001673183.1 PFAM: protein of unknown function DUF52; KEGG: azo:azo1680 hypothetical protein YP_001673184.1 PFAM: Radical SAM domain protein; KEGG: mtf:TBFG_13159 pyruvate formate lyase activating protein PflA YP_001673185.1 KEGG: slo:Shew_0921 hypothetical protein YP_001673186.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: slo:Shew_0922 methyl-accepting chemotaxis sensory transducer YP_001673187.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001673188.1 PFAM: DNA polymerase III chi subunit HolC; KEGG: slo:Shew_0924 DNA polymerase III chi subunit, HolC YP_001673189.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: sbm:Shew185_3406 DEAD/DEAH box helicase domain protein YP_001673190.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: son:SO_3392 oxidoreductase, FMN-binding YP_001673191.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: vfi:VFA0031 transcriptional regulators, LysR family YP_001673192.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: vfi:VFA0032 thioredoxin peroxidase YP_001673193.1 KEGG: swi:Swit_1025 hypothetical protein YP_001673195.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: son:SO_4351 CBS domain protein YP_001673196.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001673197.1 PFAM: permease YjgP/YjgQ family protein; KEGG: saz:Sama_0796 hypothetical protein YP_001673198.1 PFAM: permease YjgP/YjgQ family protein; KEGG: slo:Shew_0941 permease YjgP/YjgQ family protein YP_001673199.1 PFAM: RDD domain containing protein; KEGG: slo:Shew_0942 RDD domain containing protein YP_001673200.1 KEGG: slo:Shew_0943 hypothetical protein YP_001673201.1 PFAM: GCN5-related N-acetyltransferase; KEGG: slo:Shew_0944 GCN5-related N-acetyltransferase YP_001673202.1 PFAM: peptidase M32 carboxypeptidase Taq metallopeptidase; KEGG: shn:Shewana3_2999 peptidase M32, carboxypeptidase Taq metallopeptidase YP_001673203.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; protease-associated PA domain protein; KEGG: slo:Shew_2720 peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001673204.1 KEGG: son:SO_1380 hypothetical protein YP_001673205.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: shm:Shewmr7_2892 DEAD/DEAH box helicase domain protein YP_001673206.1 PFAM: creatinase; peptidase M24; KEGG: sbl:Sbal_3085 peptidase M24 YP_001673207.1 PFAM: peptidase M24; KEGG: slo:Shew_0955 peptidase M24 YP_001673208.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: shn:Shewana3_2983 peptidylprolyl isomerase, FKBP-type YP_001673209.1 PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: son:SO_A0114 outer membrane protein A YP_001673210.1 PFAM: Ig domain protein group 2 domain protein; KEGG: sbl:Sbal_4398 Ig domain protein, group 2 domain protein YP_001673211.1 PFAM: Cold-shock protein DNA-binding; protein of unknown function DUF1294; SMART: Cold shock protein; KEGG: sdn:Sden_2865 protein of unknown function DUF1294 YP_001673212.1 PFAM: regulatory protein ArsR; KEGG: ppr:PBPRA2744 hypothetical transcriptional regulator, ArsR family YP_001673213.1 KEGG: shm:Shewmr7_2880 hypothetical protein YP_001673214.1 PFAM: protein of unknown function DUF368; KEGG: slo:Shew_0960 protein of unknown function DUF368 YP_001673215.1 KEGG: slo:Shew_0961 hypothetical protein YP_001673216.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_0963 hypothetical protein YP_001673217.1 PFAM: protein of unknown function DUF861 cupin_3; KEGG: slo:Shew_0964 protein of unknown function DUF861, cupin_3 YP_001673218.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: slo:Shew_0965 methylmalonate-semialdehyde dehydrogenase YP_001673219.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_001673220.1 PFAM: aldehyde dehydrogenase; KEGG: shw:Sputw3181_3079 aldehyde dehydrogenase (NAD(+)) YP_001673221.1 PFAM: regulatory protein MerR; Methyltransferase type 11; KEGG: dps:DPPB100 probable transcription regulator YP_001673222.1 PFAM: GCN5-related N-acetyltransferase; KEGG: dde:Dde_3171 acetyltransferase YP_001673223.1 TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: son:SO_3778 adenylate cyclase CyaB, putative YP_001673224.1 TIGRFAM: aspartate racemase; PFAM: Asp/Glu racemase; KEGG: dps:DP1920 hypothetical protein YP_001673225.1 PFAM: FAD dependent oxidoreductase; KEGG: she:Shewmr4_2922 FAD dependent oxidoreductase YP_001673226.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: slo:Shew_0970 transcriptional regulator, XRE family YP_001673227.1 PFAM: peptidase C26; KEGG: slo:Shew_0971 peptidase C26 YP_001673228.1 PFAM: glutamine synthetase catalytic region; KEGG: slo:Shew_0972 glutamate--ammonia ligase YP_001673229.1 PFAM: extracellular solute-binding protein family 1; KEGG: slo:Shew_0973 extracellular solute-binding protein, family 1 YP_001673230.1 KEGG: slo:Shew_0974 spermidine/putrescine ABC transporter ATPase subunit; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001673231.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_0975 binding-protein-dependent transport systems inner membrane component YP_001673232.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_0976 binding-protein-dependent transport systems inner membrane component YP_001673233.1 PFAM: FAD dependent oxidoreductase; KEGG: slo:Shew_0977 FAD dependent oxidoreductase YP_001673234.1 TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: shn:Shewana3_3092 succinic semialdehyde dehydrogenase YP_001673235.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_001673236.1 PFAM: UspA domain protein; KEGG: slo:Shew_3101 UspA domain protein YP_001673237.1 TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma-70; PFAM: sigma-70 1.1 domain protein; sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70 non-essential domain protein; sigma-70 region 1.2; KEGG: slo:Shew_0996 RNA polymerase, sigma 70 subunit, RpoD family YP_001673238.1 KEGG: slo:Shew_0997 DNA primase; TIGRFAM: DNA primase; PFAM: zinc finger CHC2-family protein; TOPRIM domain protein; DNA primase DnaG DnaB-binding; DNA primase catalytic core domain; SMART: Toprim sub domain protein YP_001673239.1 KEGG: slo:Shew_0998 GatB/YqeY domain protein YP_001673240.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001673241.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001673242.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase alpha subunit; KEGG: son:SO_3563 SM-20 domain protein YP_001673243.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001673244.1 TIGRFAM: dihydroneopterin aldolase; KEGG: slo:Shew_1002 dihydroneopterin aldolase YP_001673245.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: slo:Shew_1003 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_001673246.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001673247.1 KEGG: slo:Shew_1005 rRNA (guanine-N(1)-)-methyltransferase YP_001673248.1 PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: slo:Shew_1006 ErfK/YbiS/YcfS/YnhG family protein YP_001673249.1 KEGG: slo:Shew_1007 major outer membrane lipoprotein, putative YP_001673250.1 PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: slo:Shew_1008 metal dependent phosphohydrolase YP_001673251.1 PFAM: Peptidoglycan-binding domain 1 protein; SMART: AAA ATPase; KEGG: slo:Shew_1009 peptidoglycan-binding domain 1 protein YP_001673252.1 KEGG: slo:Shew_1010 general secretion pathway protein B YP_001673253.1 PFAM: Citrate transporter; KEGG: shn:Shewana3_3073 citrate transporter YP_001673254.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001673256.1 PFAM: ApbE family lipoprotein; KEGG: vfi:VF0732 iron-sulfur cluster assembly/repair protein ApbE YP_001673257.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001673258.1 PFAM: cytochrome c class I; KEGG: sbl:Sbal_0009 monoheme cytochrome c YP_001673259.1 KEGG: son:SO_0716 monoheme cytochrome c, putative YP_001673260.1 PFAM: oxidoreductase molybdopterin binding; Mo-co oxidoreductase dimerisation domain; KEGG: sbl:Sbal_0007 oxidoreductase, molybdopterin binding YP_001673261.1 PFAM: cytochrome c class I; KEGG: sbl:Sbal_0006 monoheme cytochrome c YP_001673262.1 PFAM: Chloride channel core; KEGG: son:SO_1302 chloride channel YP_001673263.1 KEGG: slo:Shew_1016 hypothetical protein YP_001673264.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_001673265.1 KEGG: she:Shewmr4_2888 hypothetical protein YP_001673266.1 KEGG: shw:Sputw3181_3039 hypothetical protein YP_001673267.1 PFAM: Alkaline phosphatase; KEGG: vpa:VPA1073 putative alkaline phosphatase YP_001673268.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: shn:Shewana3_3062 peptidase S9, prolyl oligopeptidase active site domain protein YP_001673269.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: vvy:VV0250 outer membrane receptor protein YP_001673270.1 PFAM: transcriptional regulator domain protein; WD40 domain protein beta Propeller; KEGG: shm:Shewmr7_2965 transcriptional regulator domain protein YP_001673271.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001673272.1 PFAM: peptidase M23B; Opacity-associated protein A domain protein; KEGG: slo:Shew_1021 peptidase M23B YP_001673273.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001673274.1 KEGG: shw:Sputw3181_3035 hypothetical protein YP_001673275.1 KEGG: slo:Shew_1023 hypothetical protein YP_001673276.1 PFAM: protein of unknown function UPF0126; KEGG: slo:Shew_1024 protein of unknown function UPF0126 YP_001673277.1 KEGG: slo:Shew_1025 hypothetical protein YP_001673278.1 PFAM: cobalamin biosynthesis protein CbiB; KEGG: slo:Shew_1026 cobalamin biosynthesis protein CbiB YP_001673279.1 PFAM: purine or other phosphorylase family 1; KEGG: shn:Shewana3_3052 purine and other phosphorylases, family 1 YP_001673280.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; CHASE3 domain protein; KEGG: pin:Ping_3077 diguanylate cyclase YP_001673281.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cps:CPS_0291 acetyltransferase, GNAT family YP_001673282.1 PFAM: regulatory protein MarR; KEGG: sfr:Sfri_1943 transcriptional regulator, MarR family protein YP_001673283.1 PFAM: conserved hypothetical protein; KEGG: sfr:Sfri_1944 hypothetical protein YP_001673284.1 KEGG: sfr:Sfri_1945 putative transporter, BCCT family protein YP_001673285.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_001673286.1 catalyzes the formation of betaine from betaine aldehyde YP_001673287.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_001673288.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001673289.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_001673290.1 KEGG: shn:Shewana3_3048 conserved hypothetical radical SAM protein; TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001673291.1 PFAM: Hpt domain protein; KEGG: son:SO_1327 sensor histidine kinase-related protein YP_001673292.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: shw:Sputw3181_3025 transcriptional regulator, LysR family YP_001673293.1 KEGG: saz:Sama_0861 adenylate cyclase-related protein YP_001673294.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_001673295.1 hydrolyzes diadenosine polyphosphate YP_001673296.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; GAF domain protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: shm:Shewmr7_2946 PTSINtr with GAF domain, PtsP YP_001673297.1 PFAM: protein of unknown function DUF81; KEGG: shm:Shewmr7_2945 protein of unknown function DUF81 YP_001673298.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001673299.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_001673300.1 KEGG: slo:Shew_1043 hypothetical protein YP_001673301.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_001673302.1 PFAM: protein of unknown function DUF339; KEGG: slo:Shew_1045 protein of unknown function DUF339 YP_001673303.1 KEGG: sbm:Shew185_1237 hypothetical protein YP_001673304.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001673305.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001673306.1 PFAM: Anti sigma-E protein RseA family protein; Anti sigma-E protein RseA domain protein; KEGG: slo:Shew_1049 anti sigma-E protein, RseA YP_001673307.1 PFAM: MucB/RseB family protein; KEGG: she:Shewmr4_2852 sigma E regulatory protein, MucB/RseB YP_001673308.1 PFAM: Positive regulator of sigma(E) RseC/MucC; KEGG: son:SO_1345 sigma-E factor regulatory protein RseC YP_001673309.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001673310.1 KEGG: slo:Shew_1053 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein YP_001673311.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001673312.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001673313.1 TIGRFAM: DNA repair protein RecO; PFAM: Recombination protein O RecO; KEGG: slo:Shew_1056 DNA repair protein RecO YP_001673314.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001673315.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001673316.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bsu:BG10906 spermine/spermidine acetyltransferase YP_001673317.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: zmo:ZMO1573 predicted iron-dependent peroxidase YP_001673318.1 KEGG: slo:Shew_2460 hypothetical protein YP_001673319.1 KEGG: mgm:Mmc1_0550 hypothetical protein YP_001673320.1 PFAM: NapC/NirT cytochrome c domain protein; KEGG: vpa:VP1222 putative cytochrome c-type protein YP_001673321.1 PFAM: protein of unknown function DUF962; KEGG: slo:Shew_1059 protein of unknown function DUF962 YP_001673322.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: slo:Shew_1060 protein of unknown function DUF21 YP_001673323.1 PFAM: cytochrome c assembly protein; KEGG: sbm:Shew185_1252 cytochrome c assembly protein YP_001673324.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_001673325.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001673326.1 Essential for efficient processing of 16S rRNA YP_001673327.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001673328.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001673329.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_001673330.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_001673331.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_001673332.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: slo:Shew_1070 oxidoreductase FAD-binding domain protein YP_001673333.1 KEGG: son:SO_1365 hypothetical protein YP_001673334.1 PFAM: sodium/hydrogen exchanger; KEGG: sbm:Shew185_1263 sodium/hydrogen exchanger YP_001673335.1 TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: sbm:Shew185_1264 chorismate mutase YP_001673336.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: shn:Shewana3_1133 sigma 54 modulation protein/ribosomal protein S30EA YP_001673337.1 PFAM: cytochrome B561; KEGG: sbl:Sbal_1222 cytochrome b561 YP_001673338.1 PFAM: cytochrome c class II; KEGG: slo:Shew_1075 cytochrome c, class II YP_001673339.1 TIGRFAM: trp operon repressor; PFAM: Trp repressor; KEGG: son:SO_3419 trp operon repressor YP_001673340.1 KEGG: shn:Shewana3_1137 hypothetical protein YP_001673341.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: slo:Shew_1078 peptidylprolyl isomerase, FKBP-type YP_001673342.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001673343.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001673344.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001673345.1 KEGG: sbm:Shew185_1274 hypothetical protein YP_001673346.1 KEGG: slo:Shew_1083 apurinic endonuclease Apn1; TIGRFAM: apurinic endonuclease Apn1; PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease family 2 YP_001673347.1 PFAM: Hemerythrin HHE cation binding domain protein; KEGG: sfr:Sfri_2903 hemerythrin HHE cation binding domain protein YP_001673348.1 KEGG: son:SO_3548 hypothetical protein YP_001673349.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001673350.1 KEGG: slo:Shew_1089 transaldolase; TIGRFAM: transaldolase; PFAM: Transaldolase YP_001673351.1 PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: slo:Shew_1090 OmpA/MotB domain protein YP_001673352.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: slo:Shew_1091 phosphoketolase YP_001673353.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: son:SO_3541 sodium:alanine symporter family protein YP_001673354.1 PFAM: protein of unknown function DUF328; KEGG: slo:Shew_1093 protein of unknown function DUF328 YP_001673355.1 PFAM: regulatory protein ArsR; KEGG: saz:Sama_0920 transcriptional regulator HlyU YP_001673356.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001673357.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: slo:Shew_1097 integral membrane protein MviN YP_001673358.1 TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: slo:Shew_1098 riboflavin biosynthesis protein RibF YP_001673359.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001673360.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001673361.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: slo:Shew_1101 peptidylprolyl isomerase, FKBP-type YP_001673362.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001673363.1 TIGRFAM: type IV pilus modification protein PilV; KEGG: slo:Shew_1103 type IV pilus modification protein PilV YP_001673364.1 KEGG: slo:Shew_1104 prepilin-type cleavage/methylation-like protein YP_001673365.1 KEGG: slo:Shew_1105 type IV pilus assembly protein PilX YP_001673366.1 KEGG: slo:Shew_1106 type IV pilin biogenesis protein, putative YP_001673367.1 KEGG: shw:Sputw3181_3098 methylation site containing protein YP_001673368.1 KEGG: shm:Shewmr7_3030 hypothetical protein YP_001673369.1 KEGG: slo:Shew_1108 methylation site containing protein YP_001673370.1 TIGRFAM: general secretion pathway protein H; KEGG: slo:Shew_1109 type IV pilus biogenesis protein, putative YP_001673371.1 PFAM: nitrogen regulatory protein P-II; KEGG: saz:Sama_0935 nitrogen regulatory protein P-II YP_001673372.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: saz:Sama_0937 transcriptional regulator, LacI family YP_001673373.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: slo:Shew_1112 TonB-dependent receptor YP_001673374.1 PFAM: tryptophan halogenase; KEGG: slo:Shew_1113 tryptophan halogenase YP_001673375.1 PFAM: SapC family protein; KEGG: slo:Shew_1114 SapC family protein YP_001673376.1 PFAM: Carbohydrate-binding chitobiase/hexosaminidase-type domain protein; glycoside hydrolase family 20 domain protein; Glycoside hydrolase, family 20, catalytic core; KEGG: spc:Sputcn32_1075 beta-N-acetylhexosaminidase YP_001673377.1 PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: she:Shewmr4_2935 ATPase, BadF/BadG/BcrA/BcrD type YP_001673378.1 KEGG: shw:Sputw3181_3087 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase YP_001673379.1 KEGG: shm:Shewmr7_3014 hypothetical protein YP_001673380.1 TIGRFAM: glucose/galactose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: saz:Sama_0948 multiple antibiotic resistance (MarC)-related protein YP_001673381.1 PFAM: Fe(II) trafficking protein YggX; KEGG: slo:Shew_1122 Fe(II) trafficking protein YggX YP_001673382.1 TIGRFAM: A/G-specific adenine glycosylase; PFAM: HhH-GPD family protein; KEGG: shw:Sputw3181_1311 A/G-specific adenine glycosylase YP_001673383.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001673384.1 PFAM: protein of unknown function DUF469; KEGG: sdn:Sden_2696 protein of unknown function DUF469 YP_001673385.1 catalyzes the formation of glutamate from glutamine YP_001673386.1 KEGG: sbm:Shew185_3049 hypothetical protein YP_001673387.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_1128 transcriptional regulator, LysR family YP_001673389.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: cps:CPS_3436 C4-dicarboxylate transporter/malic acid transport protein YP_001673391.1 PFAM: regulatory protein LysR; KEGG: vpa:VPA0251 transcriptional regulator, LysR family YP_001673392.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: lpn:lpg1202 cytochrome D ubiquinol oxidase, subunit I YP_001673393.1 PFAM: protein of unknown function DUF885; KEGG: sbl:Sbal_3032 protein of unknown function DUF885 YP_001673394.1 KEGG: son:SO_3359 oxygen-independent coproporphyrinogen III oxidase, putative; TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001673395.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001673396.1 KEGG: slo:Shew_1133 hypothetical protein YP_001673397.1 PFAM: protein of unknown function DUF167; KEGG: she:Shewmr4_1190 hypothetical protein YP_001673398.1 PFAM: protein of unknown function YGGT; KEGG: slo:Shew_1135 protein of unknown function YGGT YP_001673399.1 KEGG: sfr:Sfri_2861 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_001673400.1 PFAM: alanine racemase domain protein; KEGG: sbl:Sbal_3025 alanine racemase domain protein YP_001673401.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: slo:Shew_1138 twitching motility protein YP_001673402.1 KEGG: shw:Sputw3181_1326 twitching motility protein; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001673403.1 PFAM: ferrochelatase; KEGG: shw:Sputw3181_1328 ferrochelatase YP_001673404.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001673405.1 PFAM: protein of unknown function DUF179; KEGG: slo:Shew_1144 protein of unknown function DUF179 YP_001673406.1 involved in start site selection during the initiation of translation YP_001673407.1 KEGG: sbl:Sbal_3017 hypothetical protein YP_001673408.1 KEGG: slo:Shew_1147 hypothetical protein YP_001673409.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: cps:CPS_0421 transcription regulator, LysR family YP_001673410.1 PFAM: transmembrane pair domain protein; KEGG: vha:VIBHAR_01850 hypothetical protein YP_001673411.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: pfl:PFL_2240 receptor, putative YP_001673412.1 PFAM: OmpA/MotB domain protein; KEGG: sbm:Shew185_3027 OmpA/MotB domain protein YP_001673413.1 PFAM: MscS Mechanosensitive ion channel; KEGG: slo:Shew_1152 MscS mechanosensitive ion channel YP_001673414.1 PFAM: protein of unknown function UPF0126; KEGG: sfr:Sfri_0596 protein of unknown function UPF0126 YP_001673415.1 PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sbm:Shew185_3026 threonine aldolase YP_001673416.1 KEGG: slo:Shew_1160 hypothetical protein YP_001673417.1 PFAM: protein of unknown function DUF442; KEGG: shw:Sputw3181_4004 hypothetical protein YP_001673418.1 PFAM: Integrase catalytic region; KEGG: kpn:KPN_pKPN3p05906 Sea24 YP_001673419.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: slo:Shew_1161 NADH dehydrogenase YP_001673421.1 KEGG: slo:Shew_1162 hypothetical protein YP_001673422.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_1163 efflux transporter, RND family, MFP subunit YP_001673423.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: slo:Shew_1164 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family YP_001673424.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: slo:Shew_1166 iron-containing alcohol dehydrogenase YP_001673425.1 PFAM: protein of unknown function DUF88; KEGG: sbl:Sbal_3176 protein of unknown function DUF88 YP_001673426.1 PFAM: acriflavin resistance protein; KEGG: spc:Sputcn32_2787 acriflavin resistance protein YP_001673427.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shw:Sputw3181_1226 efflux transporter, RND family, MFP subunit YP_001673428.1 PFAM: metallophosphoesterase; KEGG: slo:Shew_1182 metallophosphoesterase YP_001673429.1 PFAM: acyltransferase 3; KEGG: vvy:VVA1443 hypothetical protein YP_001673430.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001673431.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001673432.1 PFAM: ATP-cone domain protein; KEGG: slo:Shew_1186 ATP-cone domain protein YP_001673433.1 KEGG: son:SO_3469 riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein YP_001673434.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001673435.1 TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; KEGG: sdn:Sden_1146 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_001673436.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001673437.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001673438.1 KEGG: shw:Sputw3181_1239 thiamine-monophosphate kinase; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein domain protein YP_001673439.1 PFAM: phosphatidylglycerophosphatase A; KEGG: slo:Shew_1193 phosphatidylglycerophosphatase YP_001673440.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: slo:Shew_1196 DNA repair protein RecN YP_001673441.1 KEGG: vfi:VF1081 transcriptional regulator, TetR family YP_001673442.1 KEGG: ppr:PBPRB1507 hypothetical protein YP_001673443.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: shn:Shewana3_1106 transcriptional regulator, LysR family YP_001673444.1 PFAM: protein of unknown function DUF416; KEGG: slo:Shew_1199 protein of unknown function DUF416 YP_001673445.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_001673446.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_001673447.1 KEGG: slo:Shew_1202 (p)ppGpp synthetase I, SpoT/RelA; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; RelA/SpoT domain protein YP_001673448.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001673449.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001673450.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001673451.1 PFAM: Septum formation initiator; KEGG: slo:Shew_1206 septum formation initiator YP_001673452.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001673453.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001673454.1 PFAM: tRNA pseudouridine synthase D TruD; KEGG: shw:Sputw3181_1259 pseudouridylate synthase YP_001673455.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001673456.1 KEGG: sdn:Sden_1202 protein-L-isoaspartate O-methyltransferase; TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_001673457.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; KEGG: slo:Shew_1212 peptidase M23B YP_001673458.1 TIGRFAM: RNA polymerase sigma factor RpoS; RNA polymerase sigma-70; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70 region 1.2; KEGG: slo:Shew_1213 RNA polymerase, sigma 70 subunit, RpoD family YP_001673459.1 This protein performs the mismatch recognition step during the DNA repair process YP_001673460.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001673461.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001673462.1 affects carbohydrate metabolism; has regulatory role in many processes YP_001673463.1 TIGRFAM: sodium pump decarboxylase, gamma subunit; PFAM: sodium pump decarboxylase gamma subunit; KEGG: sfr:Sfri_1065 sodium pump decarboxylases, gamma subunit YP_001673464.1 catalyzes the formation of pyruvate from oxaloacetate YP_001673465.1 KEGG: sfr:Sfri_1067 sodium ion-translocating decarboxylase, beta subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit YP_001673466.1 KEGG: slo:Shew_1223 hypothetical protein YP_001673467.1 PFAM: sodium:dicarboxylate symporter; KEGG: slo:Shew_1224 sodium:dicarboxylate symporter YP_001673468.1 PFAM: peptidase M16 domain protein; KEGG: slo:Shew_1226 peptidase M16 domain protein YP_001673469.1 involved in the first step of glutathione biosynthesis YP_001673470.1 KEGG: slo:Shew_1228 hypothetical protein YP_001673471.1 KEGG: slo:Shew_1229 hypothetical protein YP_001673472.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: shn:Shewana3_3157 diguanylate cyclase with GAF sensor YP_001673473.1 KEGG: slo:Shew_1230 phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_001673474.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: sbl:Sbal_1039 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001673475.1 KEGG: slo:Shew_1232 hypothetical protein YP_001673476.1 KEGG: slo:Shew_1233 hypothetical protein YP_001673477.1 PFAM: peptidase S41; WD40 domain protein beta Propeller; SMART: PDZ/DHR/GLGF domain protein; KEGG: shw:Sputw3181_1281 peptidase S41 YP_001673478.1 PFAM: secretion protein HlyD family protein; KEGG: ppr:PBPRB1792 hypothetical secretion protein YP_001673479.1 KEGG: ppr:PBPRB1793 hypothetical protein YP_001673480.1 KEGG: slo:Shew_2686 putative lipoprotein YP_001673481.1 PFAM: OsmC family protein; KEGG: sbm:Shew185_1278 OsmC family protein YP_001673482.1 KEGG: sbl:Sbal_1233 hypothetical protein YP_001673483.1 KEGG: sbm:Shew185_1279 hypothetical protein YP_001673484.1 KEGG: spc:Sputcn32_2728 PepSY-associated TM helix domain protein YP_001673485.1 KEGG: sbl:Sbal_0110 hypothetical protein YP_001673486.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: son:SO_3403 ribosomal subunit interface protein YP_001673487.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: vha:VIBHAR_05273 hypothetical protein YP_001673488.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: vpa:VPA0465 putative NAD(P)H oxidoreductase YP_001673489.1 PFAM: NnrS family protein; KEGG: shw:Sputw3181_3742 NnrS family protein YP_001673490.1 PFAM: cytochrome c552; KEGG: slo:Shew_0505 nitrite reductase (cytochrome; ammonia-forming) YP_001673492.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: pfl:PFL_0202 transcriptional regulator, AraC family YP_001673493.1 PFAM: beta-lactamase domain protein; KEGG: pfo:Pfl_2280 beta-lactamase-like YP_001673494.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001673495.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001673498.1 PFAM: beta-lactamase; KEGG: ppr:PBPRB1966 hypothetical protein YP_001673500.1 PFAM: protein of unknown function DUF333; KEGG: sbm:Shew185_0128 protein of unknown function DUF333 YP_001673501.1 KEGG: cps:CPS_3362 putative lipoprotein YP_001673502.1 KEGG: vfi:VFA0120 hypothetical cytosolic protein YP_001673503.1 PFAM: glycosyl transferase group 1; KEGG: aba:Acid345_4031 glycosyl transferase, group 1 YP_001673504.1 PFAM: extracellular solute-binding protein family 3; sodium:dicarboxylate symporter; KEGG: slo:Shew_3001 extracellular solute-binding protein, family 3 YP_001673505.1 KEGG: rde:RD1_0117 hypothetical protein YP_001673506.1 KEGG: cps:CPS_1463 hypothetical protein YP_001673508.1 PFAM: EAL domain protein; KEGG: sec:SC4143 putative diguanylate cyclase/phosphodiesterase YP_001673509.1 PFAM: CBS domain containing protein; KEGG: mmw:Mmwyl1_2459 CBS domain containing protein YP_001673510.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds YP_001673511.1 PFAM: PEBP family protein; KEGG: vfi:VFA0932 putative phospholipid-binding protein YP_001673512.1 SMART: helix-turn-helix- domain containing protein AraC type; KEGG: vfi:VFA0931 transcriptional regulatory, AraC-like YP_001673513.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: slo:Shew_1931 alkylphosphonate utilization operon protein PhnA YP_001673514.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: shm:Shewmr7_0453 transcriptional regulator, AraC family YP_001673515.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: she:Shewmr4_3500 alkylhydroperoxidase like protein, AhpD family YP_001673516.1 PFAM: protein of unknown function DUF417; KEGG: aha:AHA_4046 MC21 protein YP_001673517.1 KEGG: sdn:Sden_3580 integrase, catalytic region YP_001673518.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: son:SO_1422 transcriptional regulator, LysR family YP_001673519.1 KEGG: sfr:Sfri_3983 methylation site containing protein YP_001673520.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: vfi:VFA0475 Sensory box/GGDEF family protein YP_001673521.1 KEGG: cpt:CpB0806 2-cys peroxiredoxin BAS1 precursor YP_001673522.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: vco:VC0395_A1249 methyl-accepting chemotaxis protein YP_001673523.1 KEGG: slo:Shew_0402 MSHA biogenesis protein MshQ YP_001673524.1 KEGG: shm:Shewmr7_2855 phage integrase family protein YP_001673525.1 KEGG: shn:Shewana3_2687 NAD-dependent DNA ligase (contains BRCT domain type II)-like protein YP_001673526.1 KEGG: shw:Sputw3181_2916 phage integrase family protein YP_001673527.1 KEGG: nmu:Nmul_A0120 ATP-dependent endonuclease of the OLD family-like YP_001673528.1 KEGG: nmu:Nmul_A0121 hypothetical protein YP_001673529.1 KEGG: shw:Sputw3181_2916 phage integrase family protein YP_001673530.1 KEGG: vvy:VV1784 hypothetical protein YP_001673531.1 PFAM: integrase family protein; KEGG: shw:Sputw3181_2916 phage integrase family protein YP_001673532.1 KEGG: shn:Shewana3_2687 NAD-dependent DNA ligase (contains BRCT domain type II)-like protein YP_001673533.1 PFAM: CI repressor; KEGG: sbl:Sbal_1269 bacteriophage CI repressor YP_001673534.1 KEGG: shm:Shewmr7_0701 hypothetical protein YP_001673535.1 PFAM: regulatory CII family protein; KEGG: shm:Shewmr7_0702 phage regulatory CII family protein YP_001673536.1 KEGG: shm:Shewmr7_0704 hypothetical protein YP_001673537.1 KEGG: shm:Shewmr7_0705 hypothetical protein YP_001673538.1 KEGG: shm:Shewmr7_0706 hypothetical protein YP_001673539.1 KEGG: sbl:Sbal_1274 hypothetical protein YP_001673540.1 KEGG: sbl:Sbal_1276 hypothetical protein YP_001673541.1 PFAM: replication gene A; KEGG: shw:Sputw3181_2905 bacteriophage replication gene A YP_001673543.1 PFAM: transcriptional activator Ogr/delta; KEGG: shw:Sputw3181_2904 phage transcriptional activator, Ogr/delta YP_001673544.1 PFAM: Variant SH3 domain protein; KEGG: bca:BCE_3400 SH3 domain protein YP_001673546.1 TIGRFAM: phage portal protein, PBSX family; PFAM: portal protein; KEGG: sbl:Sbal_1281 phage portal protein, PBSX family YP_001673547.1 PFAM: protein of unknown function DUF264; putative terminase ATPase subunit; KEGG: shm:Shewmr7_0720 protein of unknown function DUF264 YP_001673548.1 PFAM: capsid scaffolding; KEGG: shw:Sputw3181_2899 phage capsid scaffolding YP_001673549.1 TIGRFAM: phage major capsid protein, P2 family; PFAM: major capsid protein P2; KEGG: shm:Shewmr7_0722 phage major capsid protein, P2 family YP_001673550.1 KEGG: sbl:Sbal_1285 hypothetical protein YP_001673551.1 PFAM: small terminase subunit; KEGG: shm:Shewmr7_0724 putative phage gene YP_001673552.1 KEGG: shm:Shewmr7_0725 hypothetical protein YP_001673553.1 KEGG: shw:Sputw3181_2894 hypothetical protein YP_001673554.1 KEGG: shw:Sputw3181_2893 hypothetical protein YP_001673555.1 KEGG: sbl:Sbal_1290 hypothetical protein YP_001673556.1 KEGG: shm:Shewmr7_0729 prophage PSPPH06, putative tail tube protein YP_001673557.1 PFAM: zinc finger DksA/TraR C4-type; KEGG: shw:Sputw3181_2890 transcriptional regulator, TraR/DksA family YP_001673558.1 PFAM: protein of unknown function DUF847; KEGG: shw:Sputw3181_2889 protein of unknown function DUF847 YP_001673559.1 KEGG: plt:Plut_0821 hypothetical protein YP_001673560.1 KEGG: shw:Sputw3181_2887 hypothetical protein YP_001673561.1 KEGG: shm:Shewmr7_0735 hypothetical protein YP_001673562.1 TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: shm:Shewmr7_0736 phage tail tape measure protein, TP901 family YP_001673563.1 KEGG: shm:Shewmr7_0737 hypothetical protein YP_001673564.1 KEGG: sbl:Sbal_1300 putative bacteriophage protein YP_001673565.1 KEGG: shm:Shewmr7_0739 hypothetical protein YP_001673566.1 KEGG: sbl:Sbal_1303 hypothetical protein YP_001673567.1 KEGG: sbl:Sbal_1304 hypothetical protein YP_001673568.1 KEGG: shm:Shewmr7_0743 hypothetical protein YP_001673569.1 KEGG: shm:Shewmr7_0744 hypothetical protein YP_001673571.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001673572.1 PFAM: cyclase/dehydrase; KEGG: slo:Shew_1269 cyclase/dehydrase YP_001673573.1 PFAM: protein of unknown function UPF0125; KEGG: slo:Shew_1270 protein of unknown function UPF0125 YP_001673574.1 PFAM: SmpA/OmlA domain protein; KEGG: slo:Shew_1271 SmpA/OmlA domain protein YP_001673575.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: slo:Shew_1272 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase YP_001673576.1 KEGG: slo:Shew_1273 hypothetical protein YP_001673577.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shn:Shewana3_2946 diguanylate cyclase YP_001673578.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001673579.1 PFAM: Metal-dependent hydrolase HDOD; KEGG: slo:Shew_1277 putative signal transduction protein YP_001673580.1 KEGG: shm:Shewmr7_1280 hypothetical protein YP_001673581.1 PFAM: protein of unknown function DUF980; KEGG: son:SO_3335 hypothetical protein YP_001673582.1 KEGG: slo:Shew_1280 transcriptional regulator, CopG family YP_001673583.1 KEGG: slo:Shew_1281 hypothetical protein YP_001673584.1 KEGG: slo:Shew_1282 hypothetical protein YP_001673585.1 KEGG: slo:Shew_1283 NrfJ-related protein YP_001673586.1 PFAM: GCN5-related N-acetyltransferase; KEGG: slo:Shew_1284 GCN5-related N-acetyltransferase YP_001673587.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sbm:Shew185_3014 GCN5-related N-acetyltransferase YP_001673588.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: slo:Shew_1285 5'-nucleotidase YP_001673589.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; KEGG: son:SO_3316 hypothetical protein YP_001673590.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001673591.1 KEGG: slo:Shew_1288 type IV pilus biogenesis/stability protein PilW; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001673592.1 KEGG: sfr:Sfri_1115 hypothetical protein YP_001673593.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001673594.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001673595.1 KEGG: slo:Shew_1292 tetratricopeptide TPR_4 YP_001673596.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_001673597.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001673598.1 KEGG: slo:Shew_1147 hypothetical protein YP_001673599.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: nma:NMA1126 putative transmembrane transport protein YP_001673600.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: ppr:PBPRB0365 hypothetical methyl-accepting chemotaxis protein YP_001673601.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001673602.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001673603.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001673604.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: shm:Shewmr7_1307 CMP/dCMP deaminase, zinc-binding protein YP_001673605.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_001673606.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001673607.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: slo:Shew_1302 cytochrome bd ubiquinol oxidase, subunit I YP_001673608.1 KEGG: slo:Shew_1303 cytochrome d ubiquinol oxidase, subunit II; TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II YP_001673609.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: slo:Shew_1304 cyd operon protein YbgT YP_001673611.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: slo:Shew_1310 methyl-accepting chemotaxis sensory transducer YP_001673612.1 PFAM: acriflavin resistance protein; KEGG: slo:Shew_1311 acriflavin resistance protein YP_001673613.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_1312 efflux transporter, RND family, MFP subunit YP_001673614.1 PFAM: regulatory protein TetR; KEGG: she:Shewmr4_1247 transcriptional regulator, TetR family YP_001673615.1 KEGG: sbm:Shew185_2984 hypothetical protein YP_001673616.1 KEGG: slo:Shew_1316 hypothetical protein YP_001673617.1 KEGG: shw:Sputw3181_1377 protein of unknown function DUF115 YP_001673618.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: spc:Sputcn32_2629 polysaccharide biosynthesis protein CapD YP_001673619.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: shw:Sputw3181_1379 DegT/DnrJ/EryC1/StrS aminotransferase YP_001673620.1 PFAM: acylneuraminate cytidylyltransferase; KEGG: son:SO_3269 cytidylyltransferase domain protein YP_001673621.1 PFAM: glycoside hydrolase family 57; KEGG: son:SO_3268 alpha amylase domain protein YP_001673622.1 KEGG: gme:Gmet_0454 acylneuraminate cytidylyltransferase YP_001673623.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: gme:Gmet_0453 hypothetical protein YP_001673624.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: sbl:Sbal_2962 methyltransferase type 11 YP_001673625.1 PFAM: Transketolase central region; Transketolase domain protein; KEGG: sbl:Sbal_2961 transketolase, central region YP_001673626.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sbl:Sbal_2960 short-chain dehydrogenase/reductase SDR YP_001673627.1 PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; KEGG: sbl:Sbal_2959 phosphoribosylglycinamide synthetase YP_001673628.1 PFAM: N-acetylneuraminic acid synthase domain; KEGG: son:SO_3261 polysaccharide biosynthesis related-protein YP_001673629.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: pin:Ping_2637 methyltransferase type 12 YP_001673630.1 PFAM: sodium:dicarboxylate symporter; KEGG: vfi:VF0647 proton/sodium-glutamate symport protein YP_001673631.1 PFAM: beta-lactamase domain protein; KEGG: rba:RB11482 alkyl sulfatase or beta-lactamase YP_001673632.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: cps:CPS_4655 transcriptional regulator, AraC family YP_001673633.1 KEGG: shn:Shewana3_0711 response regulator receiver protein; TIGRFAM: hydrogenase, Fe-only; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; hydrogenase large subunit domain protein YP_001673634.1 PFAM: iron hydrogenase small subunit; KEGG: shn:Shewana3_0710 iron hydrogenase, small subunit YP_001673635.1 KEGG: shn:Shewana3_0709 formate dehydrogenase, putative YP_001673636.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and IscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; in Thermotoga this enzyme has an extra C-terminal domain YP_001673637.1 KEGG: son:SO_3924 hypothetical protein YP_001673638.1 catalyzes the formation of biotin from dethiobiotin and sulfur YP_001673639.1 TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; KEGG: shn:Shewana3_0705 small GTP-binding protein YP_001673640.1 KEGG: pin:Ping_3114 beta-lactamase domain protein YP_001673641.1 KEGG: pin:Ping_3113 hypothetical protein YP_001673642.1 PFAM: helicase domain protein; SMART: DEAD-like helicases; KEGG: pin:Ping_3112 ATP-dependent RNA helicase, DEAD box family protein YP_001673643.1 KEGG: ana:all0796 unknown protein YP_001673644.1 KEGG: slo:Shew_1337 hypothetical protein YP_001673645.1 KEGG: slo:Shew_1338 hypothetical protein YP_001673646.1 PFAM: protein of unknown function DUF400; KEGG: slo:Shew_1339 protein of unknown function DUF400 YP_001673647.1 PFAM: FlgN family protein; KEGG: slo:Shew_1340 FlgN family protein YP_001673648.1 PFAM: Anti-sigma-28 factor FlgM family protein; KEGG: sbm:Shew185_2966 anti-sigma-28 factor, FlgM YP_001673649.1 required for the assembly of the flagellar basal body P-ring YP_001673650.1 PFAM: response regulator receiver; CheW domain protein; KEGG: sfr:Sfri_1159 response regulator receiver modulated CheW protein YP_001673651.1 PFAM: MCP methyltransferase CheR-type; KEGG: shm:Shewmr7_1328 MCP methyltransferase, CheR-type YP_001673652.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod YP_001673653.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001673654.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_001673655.1 the hook connects flagellar basal body to the flagellar filament YP_001673656.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_001673657.1 makes up the distal portion of the flagellar basal body rod YP_001673658.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001673659.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001673660.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_001673661.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: slo:Shew_1354 flagellar hook-associated protein FlgK YP_001673662.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes. YP_001673663.1 PFAM: flagellin domain protein; KEGG: sdn:Sden_1314 flagellin-like protein YP_001673664.1 PFAM: flagellin domain protein; KEGG: sdn:Sden_1314 flagellin-like protein YP_001673665.1 PFAM: flagellar protein FlaG protein; KEGG: slo:Shew_1358 flagellar protein FlaG protein YP_001673666.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; KEGG: slo:Shew_1359 flagellar hook-associated 2 domain protein YP_001673667.1 KEGG: slo:Shew_1360 hypothetical protein YP_001673668.1 flagellin specific chaperone YP_001673669.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; flagellar regulatory FleQ domain protein; SMART: AAA ATPase; KEGG: slo:Shew_1362 sigma54 specific transcriptional regulator, fis family YP_001673670.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: PAS domain containing protein; KEGG: sbm:Shew185_2939 PAS/PAC sensor signal transduction histidine kinase YP_001673671.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: sfr:Sfri_1180 two component, sigma54 specific, transcriptional regulator, fis family protein YP_001673672.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: sbl:Sbal_2927 flagellar hook-basal body complex subunit FliE YP_001673673.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001673674.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001673675.1 PFAM: flagellar assembly protein FliH; KEGG: shn:Shewana3_1344 flagellar assembly protein FliH YP_001673676.1 involved in type III protein export during flagellum assembly YP_001673677.1 TIGRFAM: flagellar export protein FliJ; KEGG: son:SO_3224 flagellar protein FliJ YP_001673678.1 PFAM: flagellar hook-length control protein; KEGG: slo:Shew_1371 flagellar hook-length control protein YP_001673679.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_001673680.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001673681.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001673682.1 PFAM: flagellar biosynthesis protein FliO; KEGG: slo:Shew_1375 flagellar biosynthesis protein, FliO YP_001673683.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001673684.1 TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ family 3; KEGG: slo:Shew_1377 flagellar biosynthetic protein FliQ YP_001673685.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001673686.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001673687.1 membrane protein involved in the flagellar export apparatus YP_001673688.1 positive regulator of class III flagellar genes YP_001673689.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: slo:Shew_1382 cobyrinic acid a,c-diamide synthase YP_001673690.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001673691.1 PFAM: response regulator receiver; KEGG: slo:Shew_1384 response regulator receiver protein YP_001673692.1 PFAM: Chemotaxis phosphatase CheZ; KEGG: saz:Sama_2278 putative chemotaxis phosphatase, CheZ YP_001673693.1 PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; KEGG: slo:Shew_1386 CheA signal transduction histidine kinase YP_001673694.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001673695.1 KEGG: slo:Shew_1388 hypothetical protein YP_001673696.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: slo:Shew_1389 cobyrinic acid a,c-diamide synthase YP_001673697.1 PFAM: CheW domain protein; KEGG: slo:Shew_1390 CheW protein YP_001673698.1 PFAM: CheW domain protein; KEGG: slo:Shew_1391 CheW protein YP_001673699.1 KEGG: shn:Shewana3_1368 hypothetical protein YP_001673700.1 KEGG: slo:Shew_1393 FlhB domain protein YP_001673701.1 KEGG: son:SO_3198 hypothetical protein YP_001673702.1 PFAM: VacJ family lipoprotein; KEGG: sbl:Sbal_2897 VacJ family lipoprotein YP_001673703.1 PFAM: response regulator receiver; KEGG: shm:Shewmr7_1379 response regulator receiver protein YP_001673704.1 KEGG: ptr:749610 hypothetical protein LOC749610 YP_001673705.1 PFAM: S23 ribosomal protein; KEGG: vfi:VF0154 hypothetical protein YP_001673706.1 KEGG: sbl:Sbal_2895 amino acid/peptide transporter; TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor type I/II extracellular region; major facilitator superfamily MFS_1 YP_001673707.1 TIGRFAM: transcriptional activator RfaH; PFAM: NGN domain protein; KEGG: slo:Shew_1398 NusG antitermination factor YP_001673708.1 PFAM: polysaccharide export protein; KEGG: slo:Shew_1399 polysaccharide export protein YP_001673709.1 crystal structure of protein from Xanthomonas shows pentameric toroidal structure; physiological function is unknown YP_001673710.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: slo:Shew_1400 lipopolysaccharide biosynthesis protein YP_001673711.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose YP_001673712.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: spc:Sputcn32_2539 glucose-1-phosphate thymidylyltransferase YP_001673713.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: pin:Ping_3463 dTDP-4-dehydrorhamnose reductase YP_001673714.1 KEGG: sfr:Sfri_2827 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related YP_001673715.1 PFAM: polysaccharide biosynthesis protein; KEGG: bfr:BF1533 hypothetical protein YP_001673716.1 PFAM: glycosyl transferase family 2; KEGG: pat:Patl_3065 glycosyl transferase, family 2 YP_001673717.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: maq:Maqu_2619 coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein YP_001673718.1 KEGG: maq:Maqu_2618 hypothetical protein YP_001673719.1 PFAM: glycosyl transferase family 2; KEGG: tel:tlr2318 probable glycosyl transferase YP_001673720.1 KEGG: sas:SAS0105 hypothetical protein YP_001673721.1 PFAM: glycosyl transferase group 1; KEGG: gvi:glr0463 probable glycosyltransferase YP_001673722.1 PFAM: Protein of unknown function DUF1972; KEGG: sfr:Sfri_2826 glycosyl transferase, group 1 YP_001673723.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase family 4; KEGG: sfr:Sfri_2825 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase YP_001673724.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase family 4; KEGG: sfr:Sfri_2824 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase YP_001673725.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: sfr:Sfri_2820 beta-lactamase domain protein YP_001673726.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: she:Shewmr4_1330 UDP-glucose 6-dehydrogenase YP_001673727.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: shn:Shewana3_4089 NAD-dependent epimerase/dehydratase YP_001673728.1 KEGG: sdn:Sden_2548 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related YP_001673729.1 PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; KEGG: sbl:Sbal_2320 CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase YP_001673730.1 KEGG: shn:Shewana3_2003 glycerol-3-phosphate cytidylyltransferase; TIGRFAM: cytidyltransferase-related domain; glycerol-3-phosphate cytidylyltransferase; PFAM: cytidylyltransferase YP_001673731.1 KEGG: shn:Shewana3_2004 nucleotidyl transferase YP_001673732.1 KEGG: shn:Shewana3_2005 glycosyl transferase, WecB/TagA/CpsF family; TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: sugar transferase; glycosyl transferase WecB/TagA/CpsF YP_001673733.1 PFAM: glycosyl transferase family 2; KEGG: shn:Shewana3_2006 glycosyl transferase, family 2 YP_001673734.1 PFAM: polysaccharide biosynthesis protein; KEGG: shn:Shewana3_2007 polysaccharide biosynthesis protein YP_001673735.1 KEGG: shn:Shewana3_2008 hypothetical protein YP_001673736.1 KEGG: shn:Shewana3_2009 hypothetical protein YP_001673737.1 PFAM: polysaccharide export protein; KEGG: shn:Shewana3_2010 polysaccharide export protein YP_001673738.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: shn:Shewana3_2011 anti-sigma-factor antagonist YP_001673739.1 KEGG: shn:Shewana3_2012 putative anti-sigma regulatory factor, serine/threonine protein kinase YP_001673740.1 PFAM: response regulator receiver; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: shn:Shewana3_2013 response regulator receiver modulated serine phosphatase YP_001673741.1 KEGG: shn:Shewana3_2014 phosphonate ABC transporter, periplasmic phosphonate-binding protein YP_001673742.1 KEGG: shn:Shewana3_2015 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001673743.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: shn:Shewana3_2016 two component, sigma54 specific, transcriptional regulator, fis family YP_001673744.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sfr:Sfri_3709 PHP C-terminal domain protein YP_001673745.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: she:Shewmr4_2618 dTDP-4-dehydrorhamnose reductase YP_001673746.1 KEGG: slo:Shew_1426 hypothetical protein YP_001673747.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: sbm:Shew185_1185 glycoside hydrolase family 3 domain protein YP_001673748.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: slo:Shew_1427 3'(2'),5'-bisphosphate nucleotidase YP_001673749.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_001673750.1 PFAM: protein of unknown function DUF218; KEGG: slo:Shew_1429 protein of unknown function DUF218 YP_001673751.1 KEGG: sfr:Sfri_1323 hypothetical protein YP_001673752.1 PFAM: protein of unknown function DUF583; KEGG: slo:Shew_1431 protein of unknown function DUF583 YP_001673753.1 TIGRFAM: ferredoxin-type protein NapF; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: shw:Sputw3181_2718 ferredoxin-type protein NapF YP_001673754.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: shn:Shewana3_2783 UDP-glucose 4-epimerase YP_001673755.1 KEGG: sbm:Shew185_1478 UTP-glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase YP_001673756.1 phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin YP_001673757.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_001673758.1 PFAM: sigma-54 factor interaction domain-containing protein; amino acid-binding ACT domain protein; SMART: PAS domain containing protein; AAA ATPase; KEGG: slo:Shew_1437 transcriptional regulator, TyrR YP_001673759.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: sbm:Shew185_1482 fumarylacetoacetate (FAA) hydrolase YP_001673760.1 TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase domain; KEGG: shm:Shewmr7_2670 maleylacetoacetate isomerase YP_001673761.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: shn:Shewana3_1691 transcriptional regulator, LysR family YP_001673762.1 PFAM: major facilitator superfamily MFS_1; KEGG: slo:Shew_1441 major facilitator superfamily MFS_1 YP_001673763.1 KEGG: slo:Shew_1448 hypothetical protein YP_001673764.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001673765.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_1451 ABC transporter-related protein YP_001673766.1 PFAM: helix-turn-helix- domain containing protein AraC type; Ada metal-binding domain protein; AlkA domain protein; SMART: HhH-GPD family protein; KEGG: shm:Shewmr7_1432 transcriptional regulator, AraC family YP_001673767.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: son:SO_3126 methylated-DNA--protein-cysteine methyltransferase YP_001673768.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: slo:Shew_1454 DEAD/DEAH box helicase domain protein YP_001673769.1 PFAM: Dual specificity protein phosphatase; KEGG: shw:Sputw3181_1514 dual specificity protein phosphatase YP_001673770.1 PFAM: phospholipase D/Transphosphatidylase; KEGG: slo:Shew_1456 phospholipase D/transphosphatidylase YP_001673771.1 PFAM: response regulator receiver; CheW domain protein; KEGG: slo:Shew_1457 response regulator receiver modulated CheW protein YP_001673772.1 involved in the import of serine and threonine coupled with the import of sodium YP_001673773.1 KEGG: sbm:Shew185_2813 oxidoreductase domain protein YP_001673774.1 KEGG: slo:Shew_1459 hypothetical protein YP_001673775.1 PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_1442 pseudouridylate synthase YP_001673776.1 PFAM: protein of unknown function DUF479; KEGG: slo:Shew_2339 protein of unknown function DUF479 YP_001673777.1 KEGG: shn:Shewana3_1433 hypothetical protein YP_001673778.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001673779.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001673780.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_001673781.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001673782.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001673783.1 KEGG: slo:Shew_2333 hypothetical protein YP_001673784.1 PFAM: Rhodanese domain protein; KEGG: saz:Sama_2188 rhodanese-like protein YP_001673785.1 TIGRFAM: siroheme synthase; KEGG: saz:Sama_2187 precorrin-2 oxidase / ferrochelatase YP_001673786.1 PFAM: YaeQ family protein; KEGG: shw:Sputw3181_1530 YaeQ family protein YP_001673787.1 PFAM: carbon starvation protein CstA; KEGG: slo:Shew_2330 carbon starvation protein CstA YP_001673788.1 unknown function; when overproduced it confers drug-resistance YP_001673789.1 PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; KEGG: shm:Shewmr7_2501 signal transduction histidine kinase, LytS YP_001673790.1 KEGG: sfr:Sfri_1783 hypothetical protein YP_001673791.1 PFAM: type IV pilus assembly PilZ; KEGG: saz:Sama_1286 hypothetical protein YP_001673792.1 PFAM: phosphate-starvation-inducible E; KEGG: shn:Shewana3_2588 phosphate-starvation-inducible E YP_001673793.1 PFAM: inositol monophosphatase; KEGG: slo:Shew_2321 inositol monophosphatase YP_001673794.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: shw:Sputw3181_1859 RNA methyltransferase, TrmH family, group 1 YP_001673795.1 TIGRFAM: serine O-acetyltransferase; KEGG: she:Shewmr4_1737 serine O-acetyltransferase YP_001673796.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; iron-sulfur cluster assembly transcription factor IscR; PFAM: protein of unknown function UPF0074; KEGG: slo:Shew_2318 transcriptional regulator, BadM/Rrf2 family YP_001673797.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_001673798.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: slo:Shew_2316 FeS cluster assembly scaffold IscU YP_001673799.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; iron-sulfur cluster assembly protein IscA; PFAM: HesB/YadR/YfhF-family protein; KEGG: slo:Shew_2315 iron-sulfur cluster assembly protein IscA YP_001673800.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_001673801.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_001673802.1 TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: slo:Shew_2312 ferredoxin, 2Fe-2S type, ISC system YP_001673803.1 PFAM: protein of unknown function DUF528; KEGG: slo:Shew_2311 protein of unknown function DUF528 YP_001673804.1 KEGG: saz:Sama_1300 hypothetical protein YP_001673805.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001673806.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sfr:Sfri_2416 TonB-dependent receptor YP_001673807.1 KEGG: shn:Shewana3_2453 transcriptional regulators, TraR/DksA family YP_001673808.1 PFAM: dihydrouridine synthase DuS; KEGG: son:SO_2006 NifR3/Smm1 family protein YP_001673809.1 KEGG: slo:Shew_2241 hypothetical protein YP_001673810.1 PFAM: protein of unknown function DUF692; Xylose isomerase domain protein TIM barrel; KEGG: sbm:Shew185_2620 protein of unknown function DUF692 YP_001673811.1 KEGG: sdn:Sden_2385 hypothetical protein YP_001673812.1 KEGG: sfr:Sfri_2410 hypothetical protein YP_001673813.1 PFAM: protein of unknown function DUF454; KEGG: slo:Shew_2237 protein of unknown function DUF454 YP_001673814.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001673815.1 KEGG: slo:Shew_2235 DNA polymerase III, subunits gamma and tau; TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase YP_001673816.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_2234 conserved hypothetical protein 103 YP_001673817.1 KEGG: pin:Ping_1731 galactoside O-acetyltransferase YP_001673818.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: lpp:lpp2174 hypothetical protein YP_001673820.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001673821.1 molecular chaperone YP_001673822.1 PFAM: Thioredoxin domain; KEGG: slo:Shew_2231 thioredoxin domain protein YP_001673823.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001673824.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001673825.1 PFAM: PfkB domain protein; KEGG: son:SO_2020 inosine-guanosine kinase YP_001673826.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: vpa:VPA0209 hexapeptide-repeat containing-acetyltransferase YP_001673827.1 PFAM: sodium:dicarboxylate symporter; KEGG: shm:Shewmr7_1657 sodium:dicarboxylate symporter YP_001673828.1 PFAM: Ig domain protein group 1 domain protein; KEGG: sdn:Sden_2330 Ig-like, group 1 YP_001673829.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_001673830.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001673831.1 KEGG: slo:Shew_1623 hypothetical protein YP_001673832.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_001673833.1 KEGG: she:Shewmr4_1725 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001673834.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_001673835.1 PFAM: protein of unknown function UPF0227; KEGG: slo:Shew_1627 protein of unknown function UPF0227 YP_001673836.1 catalyzes the hydrolysis of acylphosphate YP_001673837.1 KEGG: sfr:Sfri_2400 hypothetical protein YP_001673838.1 KEGG: slo:Shew_1630 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases YP_001673839.1 KEGG: she:Shewmr4_1731 hypothetical protein YP_001673840.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: sbl:Sbal_2404 lipoprotein releasing system, transmembrane protein, LolC/E family YP_001673841.1 KEGG: spc:Sputcn32_2155 lipoprotein releasing system, ATP-binding protein; TIGRFAM: lipoprotein releasing system, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase YP_001673842.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: slo:Shew_1634 lipoprotein releasing system, transmembrane protein, LolC/E family YP_001673843.1 KEGG: sfr:Sfri_0576 hypothetical protein YP_001673844.1 KEGG: slo:Shew_1461 zinc carboxypeptidase-related protein YP_001673845.1 KEGG: sbm:Shew185_0087 hypothetical protein YP_001673846.1 PFAM: protein of unknown function DUF991; KEGG: slo:Shew_1489 protein of unknown function DUF991 YP_001673847.1 KEGG: shm:Shewmr7_2287 hypothetical protein YP_001673848.1 PFAM: Ion transport protein; Ion transport 2 domain protein; KEGG: she:Shewmr4_2209 ion transport protein YP_001673849.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: shw:Sputw3181_1728 MATE efflux family protein YP_001673850.1 KEGG: slo:Shew_1493 hypothetical protein YP_001673851.1 PFAM: protein of unknown function DUF437; KEGG: vvy:VVA0554 hypothetical protein YP_001673852.1 PFAM: regulatory protein TetR; KEGG: vfi:VF0296 hypothetical protein YP_001673853.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: vha:VIBHAR_06540 hypothetical protein YP_001673854.1 PFAM: acriflavin resistance protein; KEGG: vha:VIBHAR_06541 hypothetical protein YP_001673856.1 KEGG: bba:Bd2856 hypothetical protein YP_001673857.1 PFAM: purine or other phosphorylase family 1; KEGG: vpa:VPA1089 putative 5'-methylthioadenosine/S-adenosylhomocy steine nuclosidase YP_001673858.1 PFAM: Integral membrane protein TerC; KEGG: ppr:PBPRA2002 hypothetical transmembrane transportprotein YP_001673859.1 TIGRFAM: integron integrase; PFAM: integrase family protein; KEGG: sbm:Shew185_1682 integron integrase YP_001673861.1 KEGG: asa:ASA_3857 hypothetical protein YP_001673862.1 KEGG: ppr:PBPRA1434 hypothetical Ap4A phosphorylase II YP_001673863.1 KEGG: slo:Shew_1496 lipoprotein, putative YP_001673864.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: shw:Sputw3181_0824 glutathione-dependent formaldehyde-activating, GFA YP_001673865.1 PFAM: UspA domain protein; KEGG: slo:Shew_3100 UspA domain protein YP_001673866.1 PFAM: sodium:dicarboxylate symporter; KEGG: she:Shewmr4_0147 sodium:dicarboxylate symporter YP_001673867.1 PFAM: band 7 protein; KEGG: slo:Shew_1785 band 7 protein YP_001673868.1 PFAM: protein of unknown function DUF107; KEGG: sdn:Sden_2190 protein of unknown function DUF107 YP_001673869.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001673870.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001673871.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001673872.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_001673873.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_001673874.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001673876.1 KEGG: saz:Sama_3567 hypothetical protein YP_001673877.1 PFAM: Arylsulfotransferase; KEGG: ecv:APECO1_3375 arylsulfate sulfotransferase YP_001673878.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001673879.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001673880.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_001673881.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001673882.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001673883.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001673884.1 PFAM: protein of unknown function DUF1538; KEGG: slo:Shew_1497 protein of unknown function DUF1538 YP_001673885.1 PFAM: protein of unknown function DUF1538; KEGG: slo:Shew_1498 protein of unknown function DUF1538 YP_001673886.1 KEGG: sfr:Sfri_2273 putative nitrogen regulatory protein P-II YP_001673887.1 PFAM: CBS domain containing protein; KEGG: slo:Shew_1500 putative signal transduction protein with CBS domains YP_001673888.1 PFAM: regulatory protein RecX; KEGG: sfr:Sfri_0228 regulatory protein RecX YP_001673890.1 PFAM: PEBP family protein; KEGG: rpa:RPA0709 hypothetical protein YP_001673891.1 KEGG: shm:Shewmr7_2487 glutaredoxin YP_001673892.1 PFAM: peptidase S51 dipeptidase E; KEGG: slo:Shew_1665 peptidase S51, dipeptidase E YP_001673893.1 PFAM: protein of unknown function DUF748; KEGG: slo:Shew_1502 protein of unknown function DUF748 YP_001673894.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: slo:Shew_1503 oxidoreductase FAD-binding domain protein YP_001673895.1 KEGG: slo:Shew_1505 hypothetical protein YP_001673896.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sfr:Sfri_1598 glyoxalase/bleomycin resistance protein/dioxygenase YP_001673897.1 KEGG: slo:Shew_1507 5-carboxymethyl-2-hydroxymuconate isomerase YP_001673898.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_001673899.1 PFAM: peptidase M28; KEGG: shn:Shewana3_2548 peptidase M28 YP_001673900.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: saz:Sama_2099 NagD protein YP_001673901.1 KEGG: ppr:PBPRB0205 hypothetical FOG: GGDEF domain; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein YP_001673902.1 PFAM: protein of unknown function DUF1214; protein of unknown function DUF1254; KEGG: vha:VIBHAR_02425 hypothetical protein YP_001673903.1 PFAM: TrkA-N domain protein; Ion transport protein; Ion transport 2 domain protein; KEGG: sdy:SDY_1308 putative potassium channel protein YP_001673904.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001673905.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001673906.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001673907.1 PFAM: Gluconate transporter; Citrate transporter; Na+/H+ antiporter NhaC; KEGG: slo:Shew_1515 Na+/H+ antiporter NhaC YP_001673908.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: slo:Shew_1516 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_001673909.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_001673910.1 PFAM: OmpA/MotB domain protein; KEGG: slo:Shew_1521 OmpA/MotB domain protein YP_001673911.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: slo:Shew_1522 prolyl oligopeptidase YP_001673912.1 TIGRFAM: Pol-Pal system-associated acyl-CoA thioesterase; PFAM: thioesterase superfamily protein; KEGG: shn:Shewana3_2535 4-hydroxybenzoyl-CoA thioesterase YP_001673913.1 TIGRFAM: Tol-Pal system TolQ; PFAM: MotA/TolQ/ExbB proton channel; KEGG: slo:Shew_1524 MotA/TolQ/ExbB proton channel YP_001673914.1 TIGRFAM: Biopolymer transport TolR; PFAM: Biopolymer transport protein ExbD/TolR; KEGG: slo:Shew_1525 biopolymer transport protein ExbD/TolR YP_001673915.1 TIGRFAM: Tol-Pal system TolA; PFAM: TolA family protein; KEGG: slo:Shew_1526 TolA family protein YP_001673916.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001673917.1 TIGRFAM: Peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: slo:Shew_1528 OmpA domain protein YP_001673918.1 TIGRFAM: Tol-Pal system YbgF; KEGG: slo:Shew_1529 tetratricopeptide TPR_2 repeat protein YP_001673919.1 PFAM: porin; KEGG: slo:Shew_1530 porin YP_001673920.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_001673921.1 PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: shn:Shewana3_2524 type III restriction enzyme, res subunit YP_001673922.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001673923.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: slo:Shew_1534 integral membrane sensor hybrid histidine kinase YP_001673924.1 KEGG: sfr:Sfri_1438 hypothetical protein YP_001673925.1 PFAM: FAD dependent oxidoreductase; KEGG: slo:Shew_1537 FAD dependent oxidoreductase YP_001673926.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: slo:Shew_1545 two component transcriptional regulator, LuxR family YP_001673927.1 PFAM: thioesterase superfamily protein; KEGG: saz:Sama_2075 thioesterase superfamily YP_001673928.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_001673929.1 PFAM: protein of unknown function DUF299; KEGG: son:SO_2645 hypothetical protein YP_001673930.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001673931.1 PFAM: FAD linked oxidase domain protein; KEGG: slo:Shew_1550 FAD linked oxidase domain protein YP_001673932.1 KEGG: she:Shewmr4_1594 protein of unknown function DUF1285 YP_001673933.1 PFAM: regulatory protein MarR; KEGG: shm:Shewmr7_1670 transcriptional regulator, MarR family YP_001673934.1 KEGG: slo:Shew_1553 hypothetical protein YP_001673935.1 KEGG: shw:Sputw3181_1770 hypothetical protein YP_001673936.1 PFAM: Glu/Leu/Phe/Val dehydrogenase ; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: slo:Shew_1555 Glu/Leu/Phe/Val dehydrogenase, dimerisation region YP_001673937.1 KEGG: sfr:Sfri_2264 hypothetical protein YP_001673938.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001673939.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_001673940.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001673941.1 PFAM: NUDIX hydrolase; KEGG: sfr:Sfri_2259 NUDIX hydrolase YP_001673942.1 PFAM: pseudouridine synthase; KEGG: she:Shewmr4_1605 pseudouridine synthase, Rsu YP_001673943.1 KEGG: sfr:Sfri_2257 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type YP_001673944.1 KEGG: sbm:Shew185_2467 putative cold-shock DNA-binding domain protein; TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein YP_001673945.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001673946.1 KEGG: slo:Shew_1566 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001673947.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001673948.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_001673949.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001673950.1 PFAM: 17 kDa surface antigen; KEGG: son:SO_2622 hypothetical protein YP_001673951.1 PFAM: regulatory protein GntR HTH; KEGG: sbl:Sbal_2383 putative transcriptional regulator, GntR family YP_001673952.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shw:Sputw3181_1878 lysine exporter protein (LysE/YggA) YP_001673953.1 PFAM: Glutathione S-transferase domain; KEGG: slo:Shew_1780 glutathione S-transferase, N-terminal domain YP_001673954.1 KEGG: slo:Shew_1787 hypothetical protein YP_001673955.1 PFAM: CreA family protein; KEGG: she:Shewmr4_2205 CreA family protein YP_001673956.1 KEGG: vha:VIBHAR_01338 hypothetical protein YP_001673957.1 catalyzes the formation of L-homocysteine from cystathionine YP_001673958.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: slo:Shew_1790 integral membrane sensor signal transduction histidine kinase YP_001673959.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: slo:Shew_1791 two component transcriptional regulator, winged helix family YP_001673960.1 PFAM: OmpA/MotB domain protein; KEGG: sfr:Sfri_1624 OmpA/MotB domain protein YP_001673961.1 KEGG: sbl:Sbal_1843 vault protein inter-alpha-trypsin domain protein; TIGRFAM: LPXTG-motif cell wall anchor domain; PFAM: von Willebrand factor type A; Vault protein inter-alpha-trypsin domain protein; SMART: Vault protein inter-alpha-trypsin, metazoa YP_001673962.1 PFAM: peptidase C60 sortase A and B; KEGG: she:Shewmr4_2199 sortase family protein YP_001673963.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sbm:Shew185_1831 diguanylate cyclase YP_001673964.1 KEGG: slo:Shew_1585 hypothetical protein YP_001673965.1 PFAM: diacylglycerol kinase; KEGG: sbm:Shew185_1837 diacylglycerol kinase YP_001673966.1 catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_001673967.1 PFAM: nitroreductase; KEGG: sfr:Sfri_1409 nitroreductase YP_001673968.1 KEGG: pha:PSHAa2104 hypothetical protein YP_001673969.1 KEGG: shm:Shewmr7_3695 hypothetical protein YP_001673970.1 KEGG: pat:Patl_1737 hypothetical protein YP_001673973.1 KEGG: asu:Asuc_0026 putative lipoprotein YP_001673976.1 KEGG: mes:Meso_4612 hypothetical protein YP_001673977.1 KEGG: pin:Ping_2153 kinase YP_001673978.1 PFAM: GTP-binding protein HSR1-related; KEGG: pin:Ping_2152 GTP-binding protein, HSR1-related YP_001673979.1 PFAM: Ankyrin; KEGG: spu:752165 similar to ankyrin 2,3/unc44 YP_001673980.1 KEGG: pin:Ping_2688 hypothetical protein YP_001673981.1 KEGG: cpf:CPF_0359 hypothetical protein YP_001673983.1 KEGG: sbm:Shew185_1989 hypothetical protein YP_001673985.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: shm:Shewmr7_2266 protein tyrosine phosphatase YP_001673986.1 TIGRFAM: GTP1/OBG protein; PFAM: GTP-binding protein HSR1-related; KEGG: saz:Sama_0751 GTP-binding protein HflX YP_001673987.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_001673988.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: slo:Shew_1590 2OG-Fe(II) oxygenase YP_001673989.1 this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae YP_001673990.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: slo:Shew_1592 sulphate transporter YP_001673991.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: slo:Shew_1593 ribonuclease, Rne/Rng family YP_001673992.1 KEGG: slo:Shew_1594 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001673993.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: slo:Shew_1595 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_001673995.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: she:Shewmr4_2402 maf protein YP_001673996.1 PFAM: protein of unknown function DUF177; KEGG: son:SO_2781 hypothetical protein YP_001673997.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001673998.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001673999.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001674000.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: son:SO_2777 malonyl CoA-acyl carrier protein transacylase YP_001674001.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: shw:Sputw3181_2440 3-oxoacyl-(acyl-carrier-protein) reductase YP_001674002.1 carries the fatty acid chain in fatty acid biosynthesis YP_001674003.1 PFAM: Beta-ketoacyl synthase; KEGG: shm:Shewmr7_2464 beta-ketoacyl synthase YP_001674004.1 KEGG: shm:Shewmr7_2463 hypothetical protein YP_001674005.1 PFAM: thioesterase superfamily protein; KEGG: son:SO_2772 cytosolic long-chain acyl-CoA thioester hydrolase family protein YP_001674006.1 PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: slo:Shew_1609 6-phosphogluconate dehydrogenase, NAD-binding YP_001674007.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001674008.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_001674009.1 PFAM: integrase family protein; KEGG: shw:Sputw3181_2529 phage integrase family protein YP_001674011.1 KEGG: pol:Bpro_1735 hypothetical protein YP_001674012.1 KEGG: pfl:PFL_3846 hypothetical protein YP_001674013.1 KEGG: pau:PA14_53590 hypothetical protein YP_001674014.1 PFAM: Resolvase domain; KEGG: ppd:Ppro_2582 resolvase, N-terminal domain YP_001674015.1 KEGG: shn:Shewana3_4355 hypothetical protein YP_001674016.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: shn:Shewana3_4354 UBA/ThiF-type NAD/FAD binding protein YP_001674017.1 KEGG: shn:Shewana3_4353 hypothetical protein YP_001674018.1 KEGG: vvu:VV1_2025 2-methylthioadenine synthetase YP_001674020.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_001674021.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: slo:Shew_1614 cold-shock DNA-binding domain protein YP_001674023.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO_1865 ABC transporter, ATP-binding protein YP_001674024.1 KEGG: sfr:Sfri_1695 ABC-2 type transporter YP_001674025.1 PFAM: protein of unknown function DUF480; KEGG: son:SO_1867 hypothetical protein YP_001674026.1 KEGG: slo:Shew_1618 hypothetical protein YP_001674027.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001674028.1 PFAM: S-adenosylmethionine decarboxylase; KEGG: spc:Sputcn32_1648 adenosylmethionine decarboxylase YP_001674029.1 catalyzes the formation of putrescine from agmatine YP_001674030.1 KEGG: sfr:Sfri_1702 pyridoxamine 5'-phosphate oxidase; TIGRFAM: pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding YP_001674031.1 PFAM: YceI family protein; KEGG: shm:Shewmr7_1636 YceI family protein YP_001674032.1 KEGG: slo:Shew_2222 hypothetical protein YP_001674033.1 PFAM: protein of unknown function DUF785; KEGG: slo:Shew_2219 protein of unknown function DUF785 YP_001674034.1 TIGRFAM: PAS sensor protein; PFAM: PAS fold-4 domain protein; KEGG: she:Shewmr4_1565 multi-sensor signal transduction histidine kinase YP_001674035.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: slo:Shew_2217 methyl-accepting chemotaxis sensory transducer YP_001674036.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001674037.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001674038.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001674039.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_001674040.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001674041.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_001674042.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001674043.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001674044.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001674045.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_001674046.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001674047.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001674048.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_001674049.1 SMART: helicase c2; KEGG: slo:Shew_2196 helicase C2 YP_001674051.1 PFAM: peptidase M22 glycoprotease; KEGG: son:SO_2586 hypothetical protein YP_001674052.1 KEGG: shw:Sputw3181_2268 hypothetical protein YP_001674053.1 KEGG: sbm:Shew185_1888 hypothetical protein YP_001674054.1 KEGG: slo:Shew_2190 hypothetical protein YP_001674055.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO_2582 hydrolase, alpha/beta fold family YP_001674056.1 Activates fatty acids by binding to coenzyme A YP_001674057.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: she:Shewmr4_2176 ribonuclease D YP_001674058.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001674059.1 TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sfr:Sfri_1736 septum site-determining protein MinD YP_001674060.1 blocks the formation of polar Z-ring septums YP_001674061.1 PFAM: protein of unknown function DUF709; KEGG: slo:Shew_2183 protein of unknown function DUF709 YP_001674062.1 TIGRFAM: lytic murein transglycosylase; KEGG: sbl:Sbal_1870 lytic murein transglycosylase YP_001674063.1 PFAM: protein of unknown function UPF0153; KEGG: sbm:Shew185_1898 protein of unknown function UPF0153 YP_001674064.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_001674065.1 involved in regulation of intracellular pH under alkaline conditions YP_001674066.1 Multifunctional regulator of fatty acid metabolism YP_001674067.1 PFAM: protein of unknown function DUF490; KEGG: shw:Sputw3181_2112 protein of unknown function DUF490 YP_001674068.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: she:Shewmr4_1836 surface antigen (D15) YP_001674069.1 PFAM: peptidase T2 asparaginase 2; KEGG: slo:Shew_2171 peptidase T2, asparaginase 2 YP_001674070.1 KEGG: vpa:VPA0120 hypothetical protein YP_001674071.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_001674072.1 PFAM: CBS domain containing protein; KEGG: shm:Shewmr7_2139 putative signal transduction protein with CBS domains YP_001674073.1 PFAM: Choloylglycine hydrolase; KEGG: sdn:Sden_0442 choloylglycine hydrolase YP_001674074.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: vvu:VV2_1000 FOG: GGDEF domain YP_001674075.1 KEGG: slo:Shew_1767 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD-like helicases YP_001674076.1 KEGG: pin:Ping_3169 ABC sugar (glycerol) transporter extracellular solute-binding protein, family 1 YP_001674077.1 KEGG: hch:HCH_01467 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_001674078.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001674079.1 TIGRFAM: exodeoxyribonuclease V, alpha subunit; KEGG: slo:Shew_2131 exodeoxyribonuclease V, alpha subunit YP_001674080.1 TIGRFAM: exodeoxyribonuclease V, beta subunit; PFAM: UvrD/REP helicase; KEGG: slo:Shew_2130 exodeoxyribonuclease V, beta subunit YP_001674081.1 TIGRFAM: exodeoxyribonuclease V, gamma subunit; PFAM: Exodeoxyribonuclease V RecC subunit; KEGG: slo:Shew_2129 exodeoxyribonuclease V, gamma subunit YP_001674082.1 PFAM: transglutaminase domain protein; KEGG: slo:Shew_2128 transglutaminase domain protein YP_001674083.1 PFAM: protein of unknown function DUF58; KEGG: shn:Shewana3_2243 protein of unknown function DUF58 YP_001674084.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: slo:Shew_2126 ATPase associated with various cellular activities, AAA_3 YP_001674085.1 PFAM: EAL domain protein; KEGG: shn:Shewana3_2237 diguanylate phosphodiesterase YP_001674086.1 PFAM: Lytic transglycosylase catalytic; KEGG: slo:Shew_2125 lytic transglycosylase, catalytic YP_001674087.1 PFAM: protein of unknown function DUF195; KEGG: shm:Shewmr7_1864 protein of unknown function DUF195 YP_001674088.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001674089.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001674090.1 KEGG: sbm:Shew185_2006 hypothetical protein YP_001674091.1 TIGRFAM: regulator of ribonuclease activity A; PFAM: Dimethylmenaquinone methyltransferase; KEGG: sbm:Shew185_2007 regulator of ribonuclease activity A YP_001674092.1 PFAM: AsmA family protein; KEGG: slo:Shew_2116 AsmA family protein YP_001674093.1 KEGG: shw:Sputw3181_2251 intracellular proteinase inhibitor domain protein YP_001674094.1 PFAM: Peptidoglycan-binding LysM; Lytic transglycosylase catalytic; MLTD_N domain protein; KEGG: slo:Shew_2115 lytic transglycosylase, catalytic YP_001674095.1 PFAM: beta-lactamase domain protein; KEGG: sfr:Sfri_2207 hydroxyacylglutathione hydrolase YP_001674096.1 PFAM: Methyltransferase type 11; KEGG: sbm:Shew185_2012 methyltransferase type 11 YP_001674097.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbm:Shew185_2013 transcriptional regulator, LysR family YP_001674098.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001674099.1 KEGG: slo:Shew_2111 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease YP_001674100.1 KEGG: saz:Sama_1879 hypothetical protein YP_001674101.1 PFAM: sodium/hydrogen exchanger; KEGG: sbm:Shew185_2017 sodium/hydrogen exchanger YP_001674102.1 KEGG: sec:SC147 hypothetical protein YP_001674103.1 PFAM: protein of unknown function DUF1568; KEGG: shm:Shewmr7_1178 protein of unknown function DUF1568 YP_001674104.1 PFAM: Integrase catalytic region; KEGG: kpn:KPN_pKPN3p05906 Sea24 YP_001674105.1 KEGG: ppr:PBPRB0447 putative serine transporter YP_001674108.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: vha:VIBHAR_02531 hypothetical protein YP_001674109.1 PFAM: regulatory protein LysR; KEGG: vha:VIBHAR_05843 hypothetical protein YP_001674110.1 PFAM: sulfatase; KEGG: pfl:PFL_0205 arylsulfatase YP_001674111.1 PFAM: Radical SAM domain protein; KEGG: vfi:VF1417 arylsulfatase regulator (Fe-S oxidoreductase) YP_001674112.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase; KEGG: pin:Ping_2142 catalase/peroxidase HPI YP_001674113.1 KEGG: ppr:PBPRB1508 hypothetical protein YP_001674114.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001674115.1 PFAM: glutamine amidotransferase class-II; KEGG: slo:Shew_2107 glutamine amidotransferase, class-II YP_001674116.1 KEGG: sbm:Shew185_2021 hypothetical protein YP_001674117.1 PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: slo:Shew_2105 methylated-DNA-(protein)-cysteine S-methyltransferase YP_001674119.1 PFAM: major facilitator superfamily MFS_1; KEGG: slo:Shew_2104 major facilitator superfamily MFS_1 YP_001674120.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001674121.1 KEGG: sbl:Sbal_2326 DTW domain containing protein YP_001674122.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: sbl:Sbal_2325 channel protein, hemolysin III family YP_001674123.1 KEGG: sbm:Shew185_2324 hypothetical protein YP_001674124.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001674125.1 KEGG: shm:Shewmr7_2096 thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; phosphomethylpyrimidine kinase; PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1 YP_001674126.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: sbl:Sbal_2024 UBA/ThiF-type NAD/FAD binding protein YP_001674127.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: spc:Sputcn32_1925 thiamine biosynthesis protein ThiS YP_001674128.1 PFAM: thiazole biosynthesis family protein; KEGG: sfr:Sfri_2197 thiazole biosynthesis family protein YP_001674129.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_001674130.1 KEGG: son:SO_A0047 hypothetical protein YP_001674131.1 PFAM: response regulator receiver; KEGG: slo:Shew_0703 response regulator receiver protein YP_001674132.1 KEGG: saz:Sama_1854 conserved hypothetical methyl-accepting chemotaxis protein YP_001674133.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: ppr:PBPRB1151 hypothetical protein YP_001674134.1 KEGG: slo:Shew_2087 hypothetical protein YP_001674135.1 KEGG: shn:Shewana3_1946 response regulator receiver protein YP_001674136.1 TIGRFAM: alpha-L-glutamate ligase-like protein; KEGG: slo:Shew_2085 alpha-L-glutamate ligase-like protein YP_001674137.1 KEGG: slo:Shew_2084 gonadoliberin III-related protein YP_001674138.1 PFAM: protein of unknown function DUF785; KEGG: slo:Shew_2083 protein of unknown function DUF785 YP_001674139.1 TIGRFAM: putative methyltransferase; PFAM: methyltransferase putative; Methyltransferase type 11; Methyltransferase type 12; KEGG: slo:Shew_2082 putative methyltransferase YP_001674140.1 TIGRFAM: putative methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: slo:Shew_2081 putative methyltransferase YP_001674141.1 KEGG: spc:Sputcn32_1934 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: extracellular solute-binding protein family 3 YP_001674142.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001674143.1 PFAM: protein of unknown function DUF28; KEGG: slo:Shew_2078 protein of unknown function DUF28 YP_001674144.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001674145.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001674146.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001674147.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: spc:Sputcn32_1940 TonB-dependent receptor YP_001674148.1 KEGG: shm:Shewmr7_1867 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001674149.1 KEGG: she:Shewmr4_2070 endonuclease III; TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_001674150.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_001674151.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_001674152.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_001674153.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001674154.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001674155.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: shm:Shewmr7_1911 electron transport complex, RnfABCDGE type, A subunit YP_001674156.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: shn:Shewana3_2167 diguanylate cyclase/phosphodiesterase YP_001674157.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001674158.1 PFAM: Rhomboid family protein; KEGG: sbl:Sbal_4542 hypothetical protein YP_001674159.1 TIGRFAM: exsB protein; PFAM: ExsB family protein; KEGG: sbl:Sbal_4541 hypothetical protein YP_001674160.1 PFAM: Radical SAM domain protein; KEGG: spc:Sputcn32_1855 radical activating enzyme YP_001674161.1 PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sbm:Shew185_2117 pyridoxal-5'-phosphate-dependent protein beta subunit YP_001674162.1 KEGG: shm:Shewmr7_1918 hypothetical protein YP_001674163.1 KEGG: slo:Shew_2058 hypothetical protein YP_001674164.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: saz:Sama_1821 putative diguanylate phosphodiesterase YP_001674165.1 KEGG: sbl:Sbal_4535 hypothetical protein YP_001674166.1 KEGG: slo:Shew_2055 hypothetical protein YP_001674167.1 PFAM: Smr protein/MutS2; KEGG: she:Shewmr4_2052 Smr protein/MutS2 YP_001674168.1 KEGG: slo:Shew_2053 peptidyl-dipeptidase A YP_001674169.1 PFAM: regulatory protein TetR; KEGG: slo:Shew_2052 transcriptional regulator, TetR family YP_001674170.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001674171.1 KEGG: slo:Shew_2050 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta YP_001674172.1 Represses the expression of the zwf, eda, glp and gap YP_001674173.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001674174.1 TIGRFAM: 6-phosphogluconolactonase; KEGG: slo:Shew_2047 6-phosphogluconolactonase YP_001674175.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001674176.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001674177.1 serine protease inhibitor, inhibits trypsin and other proteases YP_001674178.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: spc:Sputcn32_2100 cation diffusion facilitator family transporter YP_001674179.1 PFAM: regulatory protein MarR; KEGG: sbm:Shew185_2256 transcriptional regulator, MarR family YP_001674180.1 PFAM: sulfatase; protein of unknown function DUF1705; KEGG: she:Shewmr4_2103 sulfatase YP_001674181.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: slo:Shew_2040 diguanylate cyclase YP_001674182.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: slo:Shew_2039 GCN5-related N-acetyltransferase YP_001674183.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: pat:Patl_1418 transcriptional regulator, GntR family YP_001674184.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_001674185.1 KEGG: slo:Shew_1821 2-methylcitrate synthase/citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase YP_001674186.1 Catalyzes the conversion of citrate to isocitrate YP_001674187.1 TIGRFAM: putative AcnD-accessory protein PrpF; PFAM: protein of unknown function DUF453; KEGG: pen:PSEEN1906 hypothetical protein YP_001674188.1 PFAM: protein of unknown function UPF0153; KEGG: cps:CPS_2552 hypothetical protein YP_001674189.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: sbl:Sbal_2119 methyltransferase type 12 YP_001674190.1 SMART: HNH nuclease; KEGG: sbm:Shew185_2239 HNH nuclease YP_001674191.1 KEGG: pin:Ping_0512 PKD domain containing protein YP_001674192.1 PFAM: regulatory protein LuxR; KEGG: ppr:PBPRB1591 hypothetical protein YP_001674193.1 PFAM: protein of unknown function DUF1568; KEGG: sdn:Sden_0135 protein of unknown function DUF1568 YP_001674194.1 KEGG: sfr:Sfri_2082 hypothetical protein YP_001674195.1 PFAM: Calcium-binding EF-hand-containing protein; KEGG: pat:Patl_0965 putative signal transduction protein with EFhand domain YP_001674196.1 PFAM: regulatory protein TetR; KEGG: vfi:VFA0359 transcriptional regulator, TetR family YP_001674197.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: vfi:VFA0358 acriflavin resistance periplasmic protein YP_001674198.1 PFAM: acriflavin resistance protein; KEGG: vfi:VFA0357 acriflavin resistance plasma membrane protein YP_001674199.1 PFAM: von Willebrand factor type A; Vault protein inter-alpha-trypsin domain protein; SMART: Vault protein inter-alpha-trypsin, metazoa; KEGG: mxa:MXAN_0776 von Willebrand factor type A domain protein YP_001674200.1 PFAM: regulatory protein MerR; KEGG: shn:Shewana3_1805 transcriptional regulator, MerR family YP_001674202.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; protease-associated PA domain protein; KEGG: saz:Sama_1876 peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001674203.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: saz:Sama_1873 response regulator receiver protein YP_001674204.1 PFAM: ATP-binding region ATPase domain protein; Two component regulator propeller; histidine kinase dimerisation and phosphoacceptor region; KEGG: saz:Sama_1872 sensor histidine kinase YP_001674205.1 KEGG: saz:Sama_1874 hypothetical protein YP_001674206.1 KEGG: saz:Sama_1875 hypothetical protein YP_001674207.1 PFAM: Glutathione S-transferase domain; KEGG: rle:RL0881 putative glutathione S-transferase YP_001674208.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: vha:VIBHAR_05274 hypothetical protein YP_001674209.1 TIGRFAM: Phasin family protein; KEGG: ppr:PBPRB1839 hypothetical protein YP_001674210.1 TIGRFAM: poly(R)-hydroxyalkanoic acid synthase, class I; PFAM: alpha/beta hydrolase fold; Poly-beta-hydroxybutyrate polymerase domain protein; KEGG: ppr:PBPRB0352 putative polyhydroxyalkanoic acid synthase YP_001674211.1 PFAM: MaoC domain protein dehydratase; KEGG: aha:AHA_2422 enoyl-CoA hydratase YP_001674212.1 PFAM: Calcium-binding EF-hand-containing protein; KEGG: pat:Patl_0965 putative signal transduction protein with EFhand domain YP_001674213.1 KEGG: dar:Daro_1033 hypothetical protein YP_001674214.1 PFAM: glutathione synthase; glutathione synthase ATP-binding; KEGG: shw:Sputw3181_2944 glutathione synthase YP_001674215.1 KEGG: pha:PSHAa1559 hypothetical protein YP_001674216.1 PFAM: protein of unknown function UPF0118; KEGG: vfi:VF2136 hypothetical membrane spanning protein YP_001674217.1 KEGG: son:SO_A0050 toxin secretion, membrane fusion protein YP_001674218.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: sdn:Sden_3311 transposase IS116/IS110/IS902 YP_001674219.1 PFAM: protein of unknown function DUF1568; KEGG: pin:Ping_3091 hypothetical protein DUF1568 YP_001674221.1 PFAM: UvrD/REP helicase; DNA topoisomerase type IA zn finger domain protein; KEGG: sfr:Sfri_0452 UvrD/REP helicase YP_001674223.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001674224.1 PFAM: phospholipase A1; KEGG: vha:VIBHAR_02841 hypothetical protein YP_001674225.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: vfi:VFA0790 chloramphenicol acetyltransferase YP_001674226.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ppr:PBPRA1657 putative Uup, ATPase components of ABC transporters with duplicated ATPase domains YP_001674227.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: hch:HCH_02466 transcriptional regulator YP_001674228.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: plu:plu1960 hypothetical protein YP_001674229.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: mmw:Mmwyl1_1989 xylulokinase YP_001674230.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sgl:SG0612 sugar ABC transporter ATP-binding component YP_001674231.1 PFAM: inner-membrane translocator; KEGG: ypi:YpsIP31758_0911 ribose ABC transporter, permease protein YP_001674232.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: rru:Rru_A0247 periplasmic binding protein/LacI transcriptional regulator YP_001674233.1 KEGG: bld:BLi00510 YdaE YP_001674234.1 KEGG: sfr:Sfri_0770 hypothetical protein YP_001674235.1 KEGG: vvy:VV3212 hypothetical protein YP_001674236.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: slo:Shew_2037 MATE efflux family protein YP_001674237.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001674238.1 KEGG: shn:Shewana3_2041 hypothetical protein YP_001674239.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: saz:Sama_1764 short-chain dehydrogenase/reductase SDR YP_001674240.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001674241.1 TIGRFAM: translation initiation factor IF-3; PFAM: initiation factor 3; KEGG: saz:Sama_1766 translation initiation factor IF-3 YP_001674242.1 PFAM: ribosomal protein L35; KEGG: slo:Shew_2030 ribosomal protein L35 YP_001674243.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001674244.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: slo:Shew_2028 thioredoxin reductase YP_001674245.1 PFAM: peptidase M14 carboxypeptidase A; KEGG: slo:Shew_1937 peptidase M14, carboxypeptidase A YP_001674246.1 KEGG: slo:Shew_1938 hypothetical protein YP_001674247.1 PFAM: protein of unknown function DUF1315; KEGG: slo:Shew_1939 protein of unknown function DUF1315 YP_001674248.1 converts asparagine to aspartate and ammonia YP_001674249.1 KEGG: slo:Shew_1941 signal peptide peptidase SppA, 67K type; TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: peptidase S49 YP_001674250.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_1910 NADH:flavin oxidoreductase/NADH oxidase YP_001674251.1 PFAM: phosphatidylserine decarboxylase-related; KEGG: pmf:P9303_20791 hypothetical protein YP_001674252.1 PFAM: conserved hypothetical protein; KEGG: vfi:VF1977 protein YgiW precursor YP_001674253.1 KEGG: sfr:Sfri_2116 hypothetical protein YP_001674254.1 PFAM: ferredoxin; KEGG: slo:Shew_1944 ferredoxin YP_001674255.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_001674256.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001674257.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sfr:Sfri_2132 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_001674258.1 Involved in ubiquinone biosynthesis YP_001674259.1 KEGG: sfr:Sfri_2130 DNA gyrase, A subunit; TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller YP_001674260.1 PFAM: beta-lactamase; KEGG: slo:Shew_1968 beta-lactamase YP_001674261.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001674262.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001674263.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001674264.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001674265.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001674266.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001674267.1 PFAM: protein of unknown function DUF1049; KEGG: slo:Shew_1956 protein of unknown function DUF1049 YP_001674268.1 KEGG: slo:Shew_1957 hypothetical protein YP_001674269.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001674270.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sbm:Shew185_2274 short-chain dehydrogenase/reductase SDR YP_001674271.1 KEGG: slo:Shew_1960 hypothetical protein YP_001674272.1 PFAM: protein of unknown function DUF486; KEGG: vco:VC0395_A1178 hypothetical protein YP_001674273.1 TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2 transporter protein CorA family protein; KEGG: shm:Shewmr7_1720 magnesium and cobalt transport protein CorA YP_001674274.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: sbm:Shew185_2272 acyl-CoA dehydrogenase domain protein YP_001674275.1 KEGG: slo:Shew_1962 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C YP_001674276.1 KEGG: sbl:Sbal_2079 hypothetical protein YP_001674277.1 PFAM: Domain of unknown function DUF1904; KEGG: slo:Shew_1964 hypothetical protein YP_001674278.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_001674279.1 PFAM: DTW domain containing protein; KEGG: slo:Shew_1966 DTW domain containing protein YP_001674281.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: slo:Shew_1969 two component transcriptional regulator, LuxR family YP_001674282.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: slo:Shew_1970 histidine kinase YP_001674283.1 PFAM: ApbE family lipoprotein; KEGG: slo:Shew_1971 ApbE family lipoprotein YP_001674284.1 PFAM: FMN-binding domain protein; KEGG: slo:Shew_1972 FMN-binding domain protein YP_001674285.1 PFAM: porin Gram-negative type; KEGG: slo:Shew_1973 porin, gram-negative type YP_001674286.1 PFAM: pseudouridine synthase; KEGG: asa:ASA_2900 ribosomal large subunit pseudouridine synthase A YP_001674287.1 PFAM: integrase family protein; KEGG: sbm:Shew185_2263 phage integrase family protein YP_001674288.1 KEGG: sbm:Shew185_2262 hypothetical protein YP_001674289.1 PFAM: protein of unknown function DUF227; SMART: CHK kinase-like; KEGG: dre:797003 hypothetical protein LOC797003 YP_001674290.1 KEGG: pnu:Pnuc_1464 hypothetical protein YP_001674291.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: vpa:VP2146 putative oxidoreductase protein YP_001674292.1 TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; protein of unknown function DUF785; RimK domain protein ATP-grasp; KEGG: fjo:Fjoh_2582 alpha-L-glutamate ligase, RimK family YP_001674293.1 KEGG: slo:Shew_2004 hypothetical protein YP_001674294.1 KEGG: slo:Shew_2002 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001674295.1 KEGG: saz:Sama_1807 hypothetical protein YP_001674296.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent YP_001674297.1 PFAM: DsrC family protein; KEGG: sfr:Sfri_1800 DsrC family protein YP_001674298.1 PFAM: DsrH family protein; KEGG: shw:Sputw3181_2008 DsrH family protein YP_001674299.1 PFAM: DsrE family protein; KEGG: sbm:Shew185_2207 DsrE family protein YP_001674300.1 PFAM: DsrE family protein; KEGG: slo:Shew_2015 DsrE family protein YP_001674301.1 PFAM: protein of unknown function UPF0005; KEGG: sbm:Shew185_2205 protein of unknown function UPF0005 YP_001674302.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_2013 transcriptional regulator, LysR family YP_001674303.1 uncharacterized member of the major facilitator superfamily (MFS) YP_001674304.1 KEGG: pha:PSHAa2145 3 alpha-hydroxysteroid dehydrogenase/carbonyl reductase YP_001674305.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: pha:PSHAa2144 transporter YP_001674306.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate YP_001674307.1 catalyzes the formation of acetyl-CoA from acetalaldehyde YP_001674308.1 PFAM: Hydratase/decarboxylase; KEGG: pha:PSHAa2141 2-hydroxypent-2,4-dienoate hydratase (HPH) (2-oxopent-4-enoate hydratase) YP_001674309.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: pha:PSHAa2140 TesA protein YP_001674310.1 PFAM: aldehyde dehydrogenase; KEGG: pha:PSHAa2139 aldehyde dehydrogenase YP_001674311.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: pha:PSHAa2137 protein with ferredoxin subunits YP_001674312.1 PFAM: major facilitator superfamily MFS_1; KEGG: pha:PSHAa2136 transporter YP_001674313.1 PFAM: beta-lactamase domain protein; KEGG: pha:PSHAa2135 metallo-dependent enzymatic protein YP_001674314.1 PFAM: AMP-dependent synthetase and ligase; KEGG: pha:PSHAa2134 AMP-binding enzyme YP_001674315.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: pha:PSHAa2133 3-ketosteroid-delta1-dehydrogenase YP_001674316.1 activates fatty acids by binding to coenzyme A YP_001674317.1 KEGG: reu:Reut_A1574 hypothetical protein YP_001674318.1 KEGG: bur:Bcep18194_B1446 glycosyl hydrolase YP_001674319.1 PFAM: Acyl-CoA dehydrogenase type 2 domain; KEGG: pha:PSHAa0877 steroid degradation protein YP_001674320.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: pha:PSHAa0878 reductase protein YP_001674321.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pha:PSHAa0879 3-oxoacyl-(ACP) reductase YP_001674322.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: pha:PSHAa0880 NADPH dehydrogenase YP_001674323.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: dar:Daro_1211 electron transfer flavoprotein beta-subunit YP_001674324.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit ; Electron transfer flavoprotein alpha subunit; KEGG: eba:ebA6510 electron transfer flavoprotein alpha subunit YP_001674325.1 PFAM: regulatory protein LuxR; KEGG: pha:PSHAa0881 LuxR-type transcription regulator required for testosterone degradation YP_001674326.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001674327.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pha:PSHAa0883 short chain dehydrogenase YP_001674328.1 PFAM: protein of unknown function DUF35; KEGG: pha:PSHAa0884 hypothetical protein YP_001674329.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: pha:PSHAa0885 acyl-CoA dehydrogenase protein YP_001674330.1 PFAM: MaoC domain protein dehydratase; KEGG: pha:PSHAa0886 hypothetical protein YP_001674331.1 KEGG: pha:PSHAa0887 lipid-transfer protein YP_001674332.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pha:PSHAa0888 acyl-CoA dehydrogenase protein YP_001674333.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pha:PSHAa0889 acyl-CoA dehydrogenase protein YP_001674334.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pha:PSHAa0890 acyl-CoA dehydrogenase protein YP_001674335.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pha:PSHAa0892 electron acceptor reductase/NADH oxidase, FAD binding, iron-sulfur cluster binding site YP_001674336.1 PFAM: alpha/beta hydrolase fold; KEGG: pha:PSHAa0893 hydrolase acting on oxygenated substrates (epoxide hydrolase) YP_001674337.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pha:PSHAa0894 3-ketoacyl-(ACP) reductase YP_001674338.1 KEGG: pha:PSHAa0895 enzyme YP_001674339.1 activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization YP_001674340.1 KEGG: pha:PSHAa0897 nonspecific lipid-transfer protein YP_001674341.1 PFAM: MaoC domain protein dehydratase; protein of unknown function DUF35; KEGG: pha:PSHAa0898 acyl dehydratase YP_001674342.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pha:PSHAa0900 dioxygenase YP_001674343.1 PFAM: coenzyme A transferase; KEGG: pha:PSHAa0901 acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit YP_001674344.1 PFAM: coenzyme A transferase; KEGG: pha:PSHAa0902 acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit YP_001674345.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001674346.1 PFAM: 2-nitropropane dioxygenase NPD; KEGG: pha:PSHAa0904 dioxygenase YP_001674347.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001674348.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pha:PSHAa0906 isovaleryl-CoA dehydrogenase YP_001674349.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: pha:PSHAa0907 butyryl-CoA dehydrogenase YP_001674350.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001674351.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pha:PSHAa0909 short chain dehydrogenase YP_001674352.1 PFAM: Amidase; KEGG: pha:PSHAa0910 allophanate hydrolase YP_001674353.1 KEGG: vha:VIBHAR_03040 hypothetical protein YP_001674354.1 KEGG: sal:Sala_0059 hypothetical protein YP_001674355.1 PFAM: protein of unknown function DUF1302; KEGG: bur:Bcep18194_B1461 protein of unknown function DUF1302 YP_001674356.1 PFAM: protein of unknown function DUF1329; KEGG: reu:Reut_A1519 protein of unknown function DUF1329 YP_001674357.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pha:PSHAa2151 short chain dehydrogenase YP_001674358.1 PFAM: MaoC domain protein dehydratase; KEGG: pha:PSHAa2150 MaoC-like deshydratase domain YP_001674359.1 KEGG: reu:Reut_A1572 thiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001674360.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: pat:Patl_3812 enoyl-CoA hydratase/isomerase YP_001674361.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase; KEGG: ppf:Pput_1650 electron-transferring-flavoprotein dehydrogenase YP_001674362.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: gme:Gmet_2217 short-chain dehydrogenase/reductase SDR YP_001674363.1 PFAM: nuclear transport factor 2; KEGG: swi:Swit_3295 nuclear transport factor 2 YP_001674364.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: pha:PSHAa2131 acyl-CoA dehydrogenase protein YP_001674365.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pha:PSHAa2130 acyl-CoA dehydrogenase protein YP_001674366.1 PFAM: acriflavin resistance protein; KEGG: sfr:Sfri_1929 acriflavin resistance protein YP_001674367.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sfr:Sfri_1930 efflux transporter, RND family, MFP subunit YP_001674368.1 PFAM: SEC-C motif domain protein; KEGG: shw:Sputw3181_1017 sec-C motif domain protein YP_001674369.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001674370.1 KEGG: ppr:PBPRB0364 putative ATP-dependent protease La-relatedprotein YP_001674371.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: vfi:VFA0990 trimethylamine-N-oxide reductase YP_001674372.1 PFAM: peptidase U32; KEGG: ppr:PBPRA1758 putative collagenase family protease YP_001674373.1 SMART: Rhodanese domain protein; KEGG: aae:aq_1599 hypothetical protein YP_001674374.1 KEGG: ppr:PBPRB1179 hypothetical protein YP_001674375.1 KEGG: sfr:Sfri_3117 hypothetical protein YP_001674376.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_001674377.1 PFAM: beta-lactamase domain protein; KEGG: son:SO_A0149 hypothetical protein YP_001674378.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001674379.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: vha:VIBHAR_05320 hypothetical protein YP_001674380.1 KEGG: vpa:VPA0396 putative outer membrane lipoprotein YP_001674381.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: vvu:VV2_0169 permease of the major facilitator superfamily YP_001674382.1 PFAM: secretion protein HlyD family protein; KEGG: vpa:VPA0097 putative secretion protein YP_001674383.1 KEGG: vfi:VF1267 DNA polymerase V YP_001674384.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_2037 efflux transporter, RND family, MFP subunit YP_001674385.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_2036 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family YP_001674386.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: shm:Shewmr7_2035 RND efflux system, outer membrane lipoprotein, NodT family YP_001674387.1 PFAM: UMUC domain protein DNA-repair protein; KEGG: sdn:Sden_3235 DNA-directed DNA polymerase YP_001674388.1 PFAM: peptidase S24 and S26 domain protein; KEGG: sfr:Sfri_1963 putative prophage repressor YP_001674389.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: vfi:VFA0342 sensory transduction protein kinase YP_001674390.1 KEGG: ppr:PBPRB0729 hypothetical protein YP_001674391.1 KEGG: cvi:CV_1450 hypothetical protein YP_001674392.1 KEGG: saz:Sama_0739 hypothetical protein YP_001674394.1 PFAM: helicase domain protein; SMART: DEAD-like helicases; KEGG: pin:Ping_3112 ATP-dependent RNA helicase, DEAD box family protein YP_001674396.1 KEGG: ppu:PP_2292 hypothetical protein YP_001674397.1 KEGG: son:SO_1888 hypothetical protein YP_001674398.1 KEGG: cch:Cag_1860 hypothetical protein YP_001674399.1 PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: spc:Sputcn32_3844 type III restriction enzyme, res subunit YP_001674400.1 PFAM: Endonuclease I; KEGG: ppr:PBPRC0029 putative endonuclease I YP_001674401.1 PFAM: UMUC domain protein DNA-repair protein; KEGG: sdn:Sden_3235 DNA-directed DNA polymerase YP_001674402.1 PFAM: peptidase S24 and S26 domain protein; KEGG: sfr:Sfri_1963 putative prophage repressor YP_001674403.1 KEGG: vpa:VPA1255 hypothetical protein YP_001674404.1 PFAM: FRG domain protein; KEGG: pla:Plav_0332 FRG domain protein YP_001674406.1 KEGG: vpa:VP2902 hypothetical protein YP_001674407.1 KEGG: vpa:VP2901 hypothetical protein YP_001674408.1 KEGG: pcr:Pcryo_1366 hypothetical protein YP_001674409.1 KEGG: pcr:Pcryo_1367 hypothetical protein YP_001674410.1 PFAM: integrase family protein; KEGG: pcr:Pcryo_1368 phage integrase YP_001674411.1 KEGG: pcr:Pcryo_1369 phage integrase YP_001674412.1 PFAM: integrase family protein; KEGG: sbm:Shew185_2174 phage integrase family protein YP_001674413.1 KEGG: sfr:Sfri_2008 hypothetical protein YP_001674414.1 KEGG: son:SO_2365 hypothetical protein YP_001674415.1 CcoN; FixN YP_001674416.1 CcoO; FixO YP_001674417.1 PFAM: Cbb3-type cytochrome oxidase component; KEGG: sdn:Sden_1849 Cbb3-type cytochrome oxidase component YP_001674418.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III; PFAM: cytochrome c class I; KEGG: slo:Shew_1988 cytochrome c oxidase, cbb3-type, subunit III YP_001674419.1 KEGG: slo:Shew_1989 hypothetical protein YP_001674420.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: shm:Shewmr7_1964 heavy metal translocating P-type ATPase YP_001674421.1 TIGRFAM: cytochrome oxidase maturation protein, cbb3-type; PFAM: cytochrome oxidase maturation protein cbb3-type; KEGG: slo:Shew_1991 cytochrome oxidase maturation protein, cbb3-type YP_001674422.1 KEGG: sbl:Sbal_4494 hypothetical protein YP_001674423.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_001674424.1 with UspC and UspD is involved in resistance to UV irradiation YP_001674425.1 PFAM: PP-loop domain protein; KEGG: shw:Sputw3181_2056 PP-loop domain protein YP_001674426.1 KEGG: slo:Shew_1996 hypothetical protein YP_001674427.1 KEGG: slo:Shew_1997 Bax protein, putative YP_001674428.1 PFAM: protein of unknown function UPF0052 and CofD; KEGG: slo:Shew_1998 protein of unknown function UPF0052 and CofD YP_001674429.1 PFAM: HPP family protein?; KEGG: vpa:VPA1561 hypothetical protein YP_001674430.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001674431.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001674432.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001674433.1 PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: slo:Shew_2022 AAA ATPase, central domain protein YP_001674434.1 PFAM: outer membrane lipoprotein carrier protein LolA; KEGG: spc:Sputcn32_2010 outer membrane lipoprotein carrier protein LolA YP_001674435.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: slo:Shew_2024 cell divisionFtsK/SpoIIIE YP_001674436.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_001674437.1 TIGRFAM: alanine dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Shikimate/quinate 5-dehydrogenase; alanine dehydrogenase/PNT domain protein; KEGG: slo:Shew_2026 alanine dehydrogenase YP_001674438.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: saz:Sama_1718 response regulator receiver protein YP_001674439.1 PFAM: protein of unknown function DUF885; KEGG: slo:Shew_1935 protein of unknown function DUF885 YP_001674440.1 KEGG: pin:Ping_3396 23S rRNA (Gm2251)-methyltransferase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases YP_001674441.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: slo:Shew_1933 endonuclease/exonuclease/phosphatase YP_001674442.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_001674444.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_001674445.1 PFAM: Endonuclease I; KEGG: pat:Patl_1033 endonuclease I YP_001674446.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: vvy:VV3056 predicted extracellular nuclease YP_001674447.1 KEGG: vvy:VV3057 hypothetical protein YP_001674448.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; Nitrate and nitrite sensing domain protein; KEGG: sbm:Shew185_1950 methyl-accepting chemotaxis sensory transducer YP_001674449.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001674450.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: spc:Sputcn32_1887 catalytic domain of components of various dehydrogenase complexes YP_001674451.1 PFAM: Transketolase central region; Transketolase domain protein; KEGG: sbl:Sbal_4507 hypothetical protein YP_001674452.1 PFAM: dehydrogenase E1 component; KEGG: slo:Shew_1925 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) YP_001674453.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_001674454.1 TIGRFAM: peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A; KEGG: saz:Sama_1707 protein-methionine-S-oxide reductase YP_001674455.1 KEGG: sfr:Sfri_2052 hypothetical protein YP_001674456.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001674457.1 negative modulator of the initiation of chromosome replication YP_001674458.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: shm:Shewmr7_1942 alpha/beta hydrolase fold YP_001674459.1 KEGG: slo:Shew_1919 hypothetical protein YP_001674460.1 KEGG: slo:Shew_1918 CopG domain protein DNA-binding domain protein YP_001674461.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001674462.1 KEGG: shm:Shewmr7_1938 hypothetical protein YP_001674463.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001674464.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001674465.1 KEGG: son:SO_2484 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region YP_001674466.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_001674467.1 PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: slo:Shew_1911 multiple antibiotic resistance (MarC)-related protein YP_001674468.1 PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: slo:Shew_1910 iron-containing alcohol dehydrogenase YP_001674469.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_001674470.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sfr:Sfri_3138 transcriptional regulator, LysR family protein YP_001674471.1 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates YP_001674472.1 KEGG: sdn:Sden_3340 methylation YP_001674473.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: slo:Shew_1905 peptidase S9, prolyl oligopeptidase active site domain protein YP_001674474.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: slo:Shew_1904 hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit YP_001674475.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: shw:Sputw3181_2219 para-aminobenzoate synthase, subunit I YP_001674476.1 PFAM: NUDIX hydrolase; KEGG: son:SO_2220 MutT/nudix family protein YP_001674477.1 KEGG: sdn:Sden_1957 hypothetical protein YP_001674478.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001674479.1 KEGG: slo:Shew_1765 hydrogenase (NiFe) small subunit HydA; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Nickel-iron dehydrogenase small subunit domain protein YP_001674480.1 PFAM: nickel-dependent hydrogenase large subunit; KEGG: slo:Shew_1764 nickel-dependent hydrogenase, large subunit YP_001674481.1 TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: slo:Shew_1763 Ni/Fe-hydrogenase, b-type cytochrome subunit YP_001674482.1 TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: slo:Shew_1762 hydrogenase expression/formation protein YP_001674483.1 KEGG: slo:Shew_1761 hypothetical protein YP_001674484.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC domain; zinc finger HypF domain protein; KEGG: spc:Sputcn32_2093 (NiFe) hydrogenase maturation protein HypF YP_001674485.1 TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: shw:Sputw3181_2173 hydrogenase accessory protein HypB YP_001674486.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: saz:Sama_1672 hydrogenase assembly chaperone HypC/HupF YP_001674487.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: slo:Shew_1757 hydrogenase expression/formation protein HypD YP_001674488.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: slo:Shew_1756 hydrogenase expression/formation protein HypE YP_001674489.1 PFAM: hydrogenase expression/synthesis HypA; KEGG: shw:Sputw3181_2177 hydrogenase nickel insertion protein HypA YP_001674490.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: ppr:PBPRB0600 hypothetical protein YP_001674491.1 PFAM: type II secretion system protein; KEGG: ppr:PBPRB0601 hypothetical putative tight adherence TadC-related transmembrane protein YP_001674492.1 PFAM: type II secretion system protein; KEGG: vpa:VP2411 putative tight adherence TadB-related transmembrane protein YP_001674493.1 PFAM: type II secretion system protein E; KEGG: ppr:PBPRB0603 putative pilus assembly protein YP_001674494.1 KEGG: vvy:VV2654 flp pilus assembly protein, ATPase CpaE YP_001674495.1 PFAM: TadE family protein; KEGG: ppr:PBPRB0605 hypothetical protein YP_001674496.1 PFAM: TadE family protein; KEGG: ppr:PBPRB0606 hypothetical protein YP_001674497.1 KEGG: ppr:PBPRB0607 hypothetical protein YP_001674499.1 PFAM: type II and III secretion system protein; transport-associated; KEGG: vvy:VV2660 flp pilus assembly protein, secretin CpaC YP_001674500.1 PFAM: SAF domain protein; KEGG: vvu:VV1_1748 flp pilus assembly protein CpaB YP_001674501.1 SMART: AAA ATPase; KEGG: ppr:PBPRB0612 hypothetical protein YP_001674502.1 PFAM: peptidase A24A prepilin type IV; KEGG: rba:RB5170 similar to type IV prepilin peptidase CpaA YP_001674504.1 KEGG: vvy:VV0172 transposase and inactivated derivative YP_001674505.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: asa:ASA_1213 hypothetical protein YP_001674506.1 PFAM: sulfatase; KEGG: lpp:lpp2806 hypothetical protein YP_001674507.1 PFAM: glycosyl transferase family 39 YP_001674508.1 PFAM: glycosyl transferase family 2; KEGG: rru:Rru_A2124 glycosyl transferase, family 2 YP_001674509.1 PFAM: Methionine biosynthesis MetW protein; Methyltransferase type 11; Methyltransferase type 12; KEGG: aba:Acid345_3127 methyltransferase type 11 YP_001674511.1 PFAM: glycosyl transferase family 9; KEGG: wsu:WS1450 ADP-heptose-LPS heptosyltransferase II (RfaF) YP_001674512.1 KEGG: rca:Rcas_4270 hypothetical protein YP_001674513.1 PFAM: Fmu (Sun) domain protein; KEGG: son:SO_2215 sun protein, putative YP_001674514.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001674515.1 PFAM: helix-turn-helix domain protein; KEGG: sbm:Shew185_4294 transcriptional regulator, XRE family YP_001674517.1 PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: vfi:VF0656 transcription elongation factor YP_001674518.1 KEGG: rme:Rmet_1758 hypothetical protein YP_001674519.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji jmjC domain protein; KEGG: sbl:Sbal_2354 cupin 4 family protein YP_001674520.1 KEGG: ppr:PBPRB1229 putative DNA polymerase III; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease YP_001674521.1 KEGG: shn:Shewana3_2253 hypothetical protein YP_001674522.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; Cache type 2 domain protein; KEGG: slo:Shew_1868 methyl-accepting chemotaxis sensory transducer YP_001674523.1 KEGG: slo:Shew_1867 hypothetical protein YP_001674524.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: shn:Shewana3_2256 phosphocarrier, HPr family YP_001674525.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: son:SO_2237 phosphotransferase system, enzyme I YP_001674526.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_001674527.1 PFAM: arsenate reductase and related; KEGG: shw:Sputw3181_1889 arsenate reductase YP_001674528.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001674529.1 PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; KEGG: sfr:Sfri_1764 peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins YP_001674530.1 PFAM: alpha/beta hydrolase fold; KEGG: shw:Sputw3181_1886 alpha/beta hydrolase fold YP_001674531.1 PFAM: carbonic anhydrase; KEGG: slo:Shew_1859 carbonate dehydratase YP_001674532.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: slo:Shew_1858 DegT/DnrJ/EryC1/StrS aminotransferase YP_001674533.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: slo:Shew_1857 iron-containing alcohol dehydrogenase YP_001674534.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001674535.1 KEGG: slo:Shew_1855 hypothetical protein YP_001674536.1 PFAM: acriflavin resistance protein; KEGG: slo:Shew_1852 acriflavin resistance protein YP_001674537.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_1851 efflux transporter, RND family, MFP subunit YP_001674538.1 PFAM: NlpBDapX family lipoprotein; KEGG: slo:Shew_1849 NlpBDapX family lipoprotein YP_001674539.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001674540.1 PFAM: amino acid-binding ACT domain protein; KEGG: slo:Shew_1847 amino acid-binding ACT domain protein YP_001674541.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shw:Sputw3181_2325 redoxin domain protein YP_001674542.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: slo:Shew_1845 lysine exporter protein (LysE/YggA) YP_001674543.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001674544.1 PFAM: protein of unknown function UPF0118; KEGG: slo:Shew_1843 protein of unknown function UPF0118 YP_001674545.1 PFAM: SirA family protein; KEGG: sdn:Sden_1648 hypothetical protein YP_001674546.1 PFAM: peptidase M48 Ste24p; SMART: Tetratricopeptide domain protein; KEGG: sbm:Shew185_1783 peptidase M48 Ste24p YP_001674547.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: spc:Sputcn32_1694 arsenate reductase YP_001674548.1 KEGG: shm:Shewmr7_2421 hypothetical protein YP_001674549.1 KEGG: sbm:Shew185_1780 hypothetical protein YP_001674550.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_001674551.1 KEGG: slo:Shew_1837 hypothetical protein YP_001674552.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: slo:Shew_1836 uracil-xanthine permease YP_001674553.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: sfr:Sfri_1748 glutaredoxin-like protein YP_001674554.1 PFAM: manganese and iron superoxide dismutase; KEGG: spc:Sputcn32_1687 superoxide dismutase YP_001674555.1 PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: slo:Shew_1833 putative serine protein kinase, PrkA YP_001674556.1 PFAM: protein of unknown function DUF444; KEGG: slo:Shew_1832 protein of unknown function DUF444 YP_001674557.1 PFAM: SpoVR family protein; KEGG: slo:Shew_1831 SpoVR family protein YP_001674558.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001674559.1 PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: shw:Sputw3181_2115 protein of unknown function DUF882 YP_001674560.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: slo:Shew_1828 peptidoglycan-binding domain 1 protein YP_001674561.1 KEGG: slo:Shew_1827 methylation site containing protein YP_001674562.1 KEGG: slo:Shew_1826 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001674563.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001674564.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_001674565.1 KEGG: son:SO_1857 hypothetical ATP-dependent protease YP_001674566.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001674567.1 PFAM: ribosome modulation factor; KEGG: slo:Shew_1816 ribosome modulation factor YP_001674568.1 KEGG: shn:Shewana3_1604 hypothetical protein YP_001674569.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_001674570.1 KEGG: shw:Sputw3181_2392 glutaredoxin 2 YP_001674571.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_001674572.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: shm:Shewmr7_2838 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001674573.1 PFAM: protein of unknown function DUF1379; KEGG: sbl:Sbal_2438 protein of unknown function DUF1379 YP_001674574.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001674575.1 PFAM: NAD-glutamate dehydrogenase; KEGG: slo:Shew_1809 NAD-glutamate dehydrogenase YP_001674576.1 KEGG: slo:Shew_1808 hypothetical protein YP_001674577.1 KEGG: shw:Sputw3181_1812 BNR repeat protein YP_001674578.1 PFAM: protein of unknown function DUF1329; KEGG: slo:Shew_1806 protein of unknown function DUF1329 YP_001674579.1 PFAM: protein of unknown function DUF1302; KEGG: slo:Shew_1805 protein of unknown function DUF1302 YP_001674580.1 KEGG: slo:Shew_1804 hypothetical protein YP_001674581.1 TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: slo:Shew_1803 aminopeptidase N YP_001674582.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_001674583.1 affects solute and DNA transport through an unknown mechanism YP_001674584.1 PFAM: GAF domain protein; KEGG: saz:Sama_1583 GAF domain-containing protein YP_001674585.1 PFAM: YebG family protein; KEGG: slo:Shew_1799 YebG family protein YP_001674586.1 PFAM: Paraquat-inducible protein A; KEGG: shm:Shewmr7_1744 paraquat-inducible protein A YP_001674587.1 PFAM: Paraquat-inducible protein A; KEGG: shw:Sputw3181_1802 paraquat-inducible protein A YP_001674588.1 PFAM: Mammalian cell entry related domain protein; KEGG: sbl:Sbal_2453 mammalian cell entry related domain protein YP_001674589.1 PFAM: nucleoside recognition domain protein; KEGG: slo:Shew_1584 nucleoside recognition domain protein YP_001674590.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_001674591.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: sfr:Sfri_2237 hydrolase, TatD family protein YP_001674592.1 KEGG: shw:Sputw3181_1797 type IV pilus biogenesis protein PilZ YP_001674593.1 TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: slo:Shew_1580 DNA polymerase III, delta prime subunit YP_001674594.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001674595.1 PFAM: aminodeoxychorismate lyase; KEGG: slo:Shew_1578 aminodeoxychorismate lyase YP_001674596.1 PFAM: aminotransferase class IV; KEGG: she:Shewmr4_1659 aminotransferase, class IV YP_001674597.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_001674598.1 KEGG: slo:Shew_1574 ATP-binding protein, Mrp/Nbp35 family YP_001674599.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001674600.1 PFAM: protein of unknown function DUF34; KEGG: shw:Sputw3181_1787 protein of unknown function DUF34 YP_001674601.1 KEGG: slo:Shew_1571 hypothetical protein YP_001674602.1 KEGG: mxa:MXAN_0539 hypothetical protein YP_001674603.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_1831 drug resistance transporter, Bcr/CflA subfamily YP_001674604.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: slo:Shew_1776 acetolactate synthase, large subunit, biosynthetic type YP_001674605.1 TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: sbm:Shew185_2375 acetolactate synthase, small subunit YP_001674606.1 PFAM: heat shock protein Hsp20; KEGG: slo:Shew_2134 heat shock protein HSP20 YP_001674607.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_001674608.1 PFAM: phospholipase/Carboxylesterase; KEGG: sdn:Sden_2138 carboxylesterase YP_001674609.1 KEGG: slo:Shew_2137 glutathione S-transferase, C-terminal domain YP_001674610.1 KEGG: slo:Shew_2138 hypothetical protein YP_001674611.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: slo:Shew_2139 peptidylprolyl isomerase, FKBP-type YP_001674612.1 TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: she:Shewmr4_2269 lytic murein transglycosylase YP_001674613.1 KEGG: sdn:Sden_2142 hypothetical protein YP_001674614.1 KEGG: sbl:Sbal_2593 hypothetical protein YP_001674615.1 PFAM: response regulator receiver; CheW domain protein; KEGG: shn:Shewana3_2462 response regulator receiver modulated CheW protein YP_001674616.1 PFAM: MscS Mechanosensitive ion channel; KEGG: slo:Shew_2145 MscS mechanosensitive ion channel YP_001674617.1 KEGG: shm:Shewmr7_2349 hypothetical protein YP_001674618.1 KEGG: shw:Sputw3181_1679 hypothetical protein YP_001674619.1 PFAM: protein of unknown function DUF307; KEGG: shw:Sputw3181_1678 protein of unknown function DUF307 YP_001674620.1 PFAM: alpha/beta hydrolase fold; KEGG: shn:Shewana3_2471 hydrolase, alpha/beta fold family YP_001674621.1 KEGG: sbm:Shew185_2644 conserved hypothetical ABC transporter protein YP_001674622.1 KEGG: slo:Shew_2150 integral membrane protein TerC YP_001674623.1 PFAM: Di-haem cytochrome c peroxidase; KEGG: shw:Sputw3181_1721 cytochrome-c peroxidase YP_001674624.1 KEGG: slo:Shew_2151 hypothetical protein YP_001674625.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: shn:Shewana3_2480 transcriptional regulator, LysR family YP_001674626.1 PFAM: homogentisate 12-dioxygenase; KEGG: sfr:Sfri_2326 homogentisate 1,2-dioxygenase YP_001674627.1 KEGG: slo:Shew_2155 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001674628.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: cps:CPS_0452 sensory box/GGDEF domain protein YP_001674629.1 KEGG: son:SO_3447 hypothetical protein YP_001674630.1 KEGG: sdn:Sden_1136 transposase YP_001674631.1 PFAM: protein of unknown function DUF1568; KEGG: pin:Ping_3091 hypothetical protein DUF1568 YP_001674632.1 KEGG: slo:Shew_2155 4-hydroxyphenylpyruvate dioxygenase YP_001674633.1 PFAM: protein of unknown function DUF442; KEGG: shw:Sputw3181_4004 hypothetical protein YP_001674634.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: son:SO_1954 transporter, LysE family YP_001674635.1 KEGG: saz:Sama_2872 hypothetical protein YP_001674637.1 KEGG: sbm:Shew185_2658 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_001674638.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific YP_001674639.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: oan:Oant_3490 major facilitator superfamily MFS_1 YP_001674640.1 KEGG: sdn:Sden_0135 protein of unknown function DUF1568 YP_001674641.1 KEGG: ppr:PBPRB0021 putative simple sugar transport system substrate-binding protein YP_001674642.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ppr:PBPRB0020 hypothetical ABC-type sugar transport system, ATPase component YP_001674643.1 PFAM: inner-membrane translocator; KEGG: ppr:PBPRB0019 putative AraH,Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components YP_001674644.1 PFAM: glycoside hydrolase family 4; KEGG: ppr:PBPRB0018 putative alpha-galactosidase (melibiase) YP_001674645.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; KEGG: slo:Shew_2159 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor YP_001674646.1 KEGG: shm:Shewmr7_2371 dipeptidase, putative; TIGRFAM: dipeptidase, putative; PFAM: peptidase M20 YP_001674647.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: slo:Shew_2161 peptidyl-dipeptidase DCP YP_001674648.1 KEGG: shn:Shewana3_2752 hypothetical protein YP_001674649.1 PFAM: protein of unknown function DUF938; KEGG: shn:Shewana3_1834 protein of unknown function DUF938 YP_001674650.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_001674651.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: sfr:Sfri_2744 acyl-CoA dehydrogenase domain protein YP_001674652.1 PFAM: Aldose 1-epimerase; KEGG: sbm:Shew185_1722 aldose 1-epimerase YP_001674654.1 KEGG: shm:Shewmr7_2186 hypothetical protein YP_001674655.1 KEGG: shn:Shewana3_1844 hypothetical protein YP_001674656.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_2168 uncharacterized conserved protein UCP025560 YP_001674657.1 KEGG: vha:VIBHAR_02135 hypothetical protein YP_001674659.1 KEGG: sbm:Shew185_1810 hypothetical protein YP_001674660.1 KEGG: sbm:Shew185_1809 hypothetical protein YP_001674661.1 KEGG: sbl:Sbal_1816 hypothetical protein YP_001674662.1 PFAM: protein of unknown function UPF0118; KEGG: ppr:PBPRA1562 hypothetical protein YP_001674663.1 PFAM: Ion transport 2 domain protein; KEGG: vpa:VPA1582 hypothetical protein YP_001674664.1 PFAM: protein of unknown function DUF214; KEGG: saz:Sama_1472 ABC transporter permease protein YP_001674665.1 KEGG: saz:Sama_1471 membrane-fusion protein YP_001674666.1 KEGG: saz:Sama_1470 membrane-fusion protein YP_001674667.1 KEGG: saz:Sama_1469 multidrug resistance efflux pump-like protein YP_001674668.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: saz:Sama_1468 putative macrolide efflux ABC transporter, ATP-binding protein YP_001674669.1 KEGG: slo:Shew_1747 hypothetical protein YP_001674670.1 KEGG: shw:Sputw3181_2406 hypothetical protein YP_001674671.1 KEGG: slo:Shew_1744 GCN5-related N-acetyltransferase YP_001674672.1 PFAM: nitroreductase; KEGG: sfr:Sfri_1532 nitroreductase YP_001674673.1 PFAM: DoxX family protein; KEGG: sfr:Sfri_1531 DoxX family protein YP_001674674.1 KEGG: sdn:Sden_2317 hypothetical protein YP_001674675.1 PFAM: aminoglycoside phosphotransferase; KEGG: slo:Shew_1738 aminoglycoside phosphotransferase YP_001674676.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: sbl:Sbal_1804 nicotinamide mononucleotide transporter PnuC YP_001674677.1 KEGG: sfr:Sfri_1527 hypothetical protein YP_001674678.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: slo:Shew_1735 TonB-dependent receptor YP_001674679.1 PFAM: protein of unknown function DUF1425; KEGG: slo:Shew_1734 protein of unknown function DUF1425 YP_001674680.1 PFAM: thioesterase superfamily protein; KEGG: son:SO_2721 hypothetical protein YP_001674681.1 PFAM: thioesterase superfamily protein; KEGG: sbm:Shew185_1791 thioesterase superfamily protein YP_001674682.1 PFAM: histidine triad (HIT) protein; KEGG: slo:Shew_1731 histidine triad (HIT) protein YP_001674683.1 PFAM: regulatory protein TetR; KEGG: tfu:Tfu_2816 hypothetical protein YP_001674686.1 PFAM: regulatory protein LuxR; KEGG: saz:Sama_1446 response regulator receiver protein YP_001674687.1 KEGG: sbl:Sbal_1794 tetratricopeptide TPR_2 repeat protein YP_001674688.1 KEGG: slo:Shew_1724 cytochrome c3 YP_001674689.1 putative metalloprotease YP_001674690.1 KEGG: sbm:Shew185_1754 dethiobiotin synthase; TIGRFAM: dethiobiotin synthase; PFAM: Cobyrinic acid ac-diamide synthase YP_001674691.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: she:Shewmr4_2357 biotin biosynthesis protein BioC YP_001674692.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: sbm:Shew185_1752 8-amino-7-oxononanoate synthase YP_001674693.1 KEGG: shn:Shewana3_2519 biotin synthase; TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_001674694.1 TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: sdn:Sden_1657 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_001674695.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001674696.1 KEGG: shn:Shewana3_1718 hypothetical protein YP_001674697.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_001674698.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_001674699.1 PFAM: GCN5-related N-acetyltransferase; KEGG: slo:Shew_1660 GCN5-related N-acetyltransferase YP_001674700.1 PFAM: ferredoxin-dependent glutamate synthase; KEGG: slo:Shew_1659 ferredoxin-dependent glutamate synthase YP_001674701.1 KEGG: ppr:PBPRA2342 hypothetical protein YP_001674702.1 TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: saz:Sama_1430 succinyl-CoA synthetase alpha chain YP_001674703.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001674704.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: slo:Shew_1656 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase YP_001674705.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001674706.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001674707.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001674708.1 TIGRFAM: Succinate dehydrogenase hydrophobic membrane anchor; KEGG: shw:Sputw3181_1736 conserved hypothetical succinate dehydrogenase, hydrophobic subunit YP_001674709.1 TIGRFAM: Succinate dehydrogenase cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: slo:Shew_1651 succinate dehydrogenase, cytochrome b subunit YP_001674710.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001674711.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_1649 efflux transporter, RND family, MFP subunit YP_001674712.1 PFAM: acriflavin resistance protein; KEGG: slo:Shew_1648 acriflavin resistance protein YP_001674713.1 PFAM: acriflavin resistance protein; KEGG: slo:Shew_1647 acriflavin resistance protein YP_001674714.1 KEGG: slo:Shew_0958 hypothetical protein YP_001674715.1 KEGG: vpa:VP1135 hypothetical protein YP_001674716.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: slo:Shew_1645 sigma54 specific transcriptional regulator, fis family YP_001674717.1 PFAM: DSBA oxidoreductase; KEGG: slo:Shew_1644 DsbA oxidoreductase YP_001674718.1 KEGG: slo:Shew_1643 hypothetical protein YP_001674719.1 PFAM: Peptidase M11 gametolysin; KEGG: slo:Shew_1642 peptidase M11, gametolysin YP_001674720.1 PFAM: protein of unknown function DUF343; KEGG: son:SO_2800 hypothetical protein YP_001674721.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001674722.1 KEGG: son:SO_2802 ABC transporter, ATP-binding protein MsbA; TIGRFAM: lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001674723.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG: shw:Sputw3181_2543 DNA internalization-related competence protein ComEC/Rec2 YP_001674724.1 KEGG: slo:Shew_1636 hypothetical protein YP_001674725.1 PFAM: peptidase M23B; KEGG: slo:Shew_1474 peptidase M23B YP_001674726.1 KEGG: slo:Shew_1473 hypothetical protein YP_001674727.1 PFAM: 37kDa nucleoid-associated protein; KEGG: slo:Shew_1472 37 kDa nucleoid-associated protein YP_001674728.1 PFAM: protein of unknown function DUF1414; KEGG: son:SO_2176 hypothetical protein YP_001674729.1 PFAM: sulfatase; KEGG: shn:Shewana3_2428 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase YP_001674730.1 KEGG: slo:Shew_2961 hypothetical protein YP_001674731.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: slo:Shew_1467 diguanylate cyclase YP_001674732.1 KEGG: sbl:Sbal_2541 hypothetical protein YP_001674733.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001674734.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: slo:Shew_1462 lysine exporter protein (LysE/YggA) YP_001674735.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: slo:Shew_2341 two component, sigma54 specific, transcriptional regulator, fis family YP_001674736.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: slo:Shew_2342 integral membrane sensor signal transduction histidine kinase YP_001674737.1 KEGG: slo:Shew_2343 hypothetical protein YP_001674738.1 PFAM: EAL domain protein; phosphotransferase system EIIC; KEGG: vvy:VVA1275 hypothetical protein YP_001674739.1 PFAM: Proprotein convertase P; KEGG: slo:Shew_1752 proprotein convertase, P YP_001674740.1 KEGG: slo:Shew_1751 hypothetical protein YP_001674741.1 PFAM: transposase IS204/IS1001/IS1096/IS1165 family protein; KEGG: rci:RCIX171 transposase YP_001674742.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sdn:Sden_1155 radical SAM YP_001674743.1 KEGG: slo:Shew_2344 hypothetical protein YP_001674744.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: saz:Sama_1545 binding-protein-dependent transport systems inner membrane component YP_001674745.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_2346 ABC transporter-related protein YP_001674746.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; KEGG: saz:Sama_1543 putative phosphonate ABC transporter, periplasmic phosphonate-binding protein YP_001674747.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sbm:Shew185_2494 two component transcriptional regulator, winged helix family YP_001674748.1 PFAM: ATP-binding region ATPase domain protein; KEGG: sbl:Sbal_2502 integral membrane sensor signal transduction histidine kinase YP_001674749.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase alpha subunit; KEGG: shm:Shewmr7_1653 prolyl 4-hydroxylase, alpha subunit YP_001674750.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ppr:PBPRB0854 hypothetical transcriptional regulator YP_001674751.1 PFAM: beta-lactamase domain protein; KEGG: vvy:VVA1356 alkyl sulfatase YP_001674752.1 KEGG: vfi:VFA0845 hypothetical protein YP_001674753.1 KEGG: shn:Shewana3_1721 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region YP_001674754.1 KEGG: saz:Sama_1538 hypothetical protein YP_001674755.1 TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2 transporter protein CorA family protein; KEGG: sbm:Shew185_2498 magnesium and cobalt transport protein CorA YP_001674756.1 KEGG: slo:Shew_2354 hypothetical protein YP_001674757.1 KEGG: shw:Sputw3181_2412 hypothetical protein YP_001674758.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: aha:AHA_0957 HTH-type transcriptional regulator XapR YP_001674759.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_001674760.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: aha:AHA_0959 nucleoside permease YP_001674761.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: aha:AHA_0961 hypothetical protein YP_001674762.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_001674763.1 PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; KEGG: slo:Shew_2358 peptidase M24 YP_001674764.1 PFAM: amino acid permease-associated region; Amino acid transporter transmembrane; KEGG: lpf:lpl0333 hypothetical protein YP_001674765.1 KEGG: pin:Ping_1766 hypothetical protein YP_001674766.1 KEGG: ana:alr4631 unknown protein YP_001674767.1 KEGG: sde:Sde_2468 amine oxidase, flavin-containing YP_001674768.1 PFAM: FAD dependent oxidoreductase; KEGG: slo:Shew_2360 D-amino-acid dehydrogenase YP_001674769.1 PFAM: proline racemase; KEGG: slo:Shew_2361 proline racemase YP_001674770.1 TIGRFAM: dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; KEGG: slo:Shew_2362 dihydrodipicolinate synthase YP_001674771.1 PFAM: proline racemase; KEGG: slo:Shew_2363 proline racemase YP_001674772.1 PFAM: aldehyde dehydrogenase; KEGG: slo:Shew_2364 aldehyde dehydrogenase YP_001674773.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: slo:Shew_2365 transcriptional regulator, GntR family YP_001674774.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis YP_001674775.1 KEGG: slo:Shew_2367 hypothetical protein YP_001674776.1 PFAM: Heme NO binding domain protein; KEGG: vfi:VFA0071 hypothetical protein YP_001674777.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: vfi:VFA0072 sensor protein LuxQ YP_001674778.1 PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: she:Shewmr4_1516 exonuclease, RNase T and DNA polymerase III YP_001674779.1 PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294 nucleotidyltransferase putative; KEGG: slo:Shew_2369 cyclic nucleotide-binding protein YP_001674780.1 PFAM: Na+/solute symporter; KEGG: slo:Shew_2371 Na+/solute symporter YP_001674781.1 KEGG: slo:Shew_2372 hypothetical protein YP_001674782.1 SMART: protein phosphatase 2C domain protein; KEGG: stt:t4521 hypothetical protein YP_001674783.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: slo:Shew_3322 RarD protein, DMT superfamily transporter YP_001674784.1 KEGG: vpa:VPA0754 hypothetical protein YP_001674785.1 PFAM: PEBP family protein; KEGG: aeh:Mlg_1616 YbhB and YbcL YP_001674786.1 PFAM: DSBA oxidoreductase; KEGG: son:SO_2860 thiol:disulfide interchange protein, DsbA family YP_001674787.1 KEGG: slo:Shew_2374 NAD-dependent epimerase/dehydratase YP_001674788.1 PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: shn:Shewana3_1571 metal dependent phosphohydrolase YP_001674789.1 KEGG: slo:Shew_2376 hypothetical protein YP_001674790.1 KEGG: slo:Shew_2377 DNA ligase, NAD-dependent; TIGRFAM: DNA ligase, NAD-dependent; PFAM: BRCT domain protein; zinc-finger NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase OB-fold; NAD-dependent DNA ligase adenylation; SMART: NAD-dependent DNA ligase YP_001674791.1 TIGRFAM: cell division protein ZipA; PFAM: ZipA FtsZ-binding region; KEGG: slo:Shew_2378 cell division protein ZipA YP_001674792.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; KEGG: slo:Shew_2379 chromosome segregation protein SMC YP_001674793.1 putative role in sulfur assimilation YP_001674794.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: saz:Sama_1511 response regulator receiver protein YP_001674795.1 PFAM: RDD domain containing protein; KEGG: shn:Shewana3_1562 RDD domain containing protein YP_001674796.1 TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: slo:Shew_2382 cysteine synthase A YP_001674797.1 PFAM: regulatory protein TetR; KEGG: slo:Shew_2383 putative transcriptional regulator, TetR family YP_001674798.1 KEGG: sfr:Sfri_2128 O-methyltransferase, putative YP_001674799.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: shw:Sputw3181_1637 C4-dicarboxylate transporter/malic acid transport protein YP_001674800.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: slo:Shew_2385 TonB-dependent receptor, plug YP_001674801.1 PFAM: C4-dicarboxylate anaerobic carrier; KEGG: shn:Shewana3_1557 C4-dicarboxylate anaerobic carrier YP_001674802.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_001674803.1 KEGG: dps:DP0461 hypothetical protein YP_001674804.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: shw:Sputw3181_1634 transcriptional regulator, LysR family YP_001674805.1 PFAM: formate/nitrite transporter; CBS domain containing protein; KEGG: shw:Sputw3181_1633 formate/nitrite transporter YP_001674806.1 KEGG: slo:Shew_2389 hypothetical protein YP_001674807.1 KEGG: slo:Shew_2390 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL YP_001674808.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_001674809.1 PFAM: protein of unknown function DUF412; KEGG: son:SO_2914 hypothetical protein YP_001674810.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001674811.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001674812.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: pin:Ping_1714 antibiotic biosynthesis monooxygenase YP_001674813.1 KEGG: shn:Shewana3_1548 hypothetical protein YP_001674814.1 KEGG: son:SO_2919 hypothetical protein YP_001674815.1 PFAM: protein of unknown function UPF0118; KEGG: slo:Shew_2398 protein of unknown function UPF0118 YP_001674816.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_001674817.1 PFAM: NAD-dependent epimerase/dehydratase; domain of unknown function DUF1731; KEGG: sfr:Sfri_2559 hypothetical protein YP_001674818.1 PFAM: protein of unknown function DUF214; KEGG: sbm:Shew185_2707 protein of unknown function DUF214 YP_001674819.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_2402 ABC transporter-related protein YP_001674820.1 PFAM: lipolytic protein G-D-S-L family; KEGG: sfr:Sfri_2568 arylesterase YP_001674821.1 KEGG: saz:Sama_1484 hypothetical protein YP_001674822.1 KEGG: slo:Shew_2404 hypothetical protein YP_001674823.1 KEGG: shm:Shewmr7_1538 hypothetical protein YP_001674824.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: son:SO_2932 transcriptional regulator, AraC family YP_001674825.1 PFAM: Methyltransferase type 12; KEGG: sdn:Sden_0896 methyltransferase type 11 YP_001674826.1 PFAM: Integrase catalytic region; KEGG: kpn:KPN_pKPN3p05906 Sea24 YP_001674827.1 SohB; periplasmic protein; member of the peptidase S49 family YP_001674828.1 KEGG: slo:Shew_2408 hypothetical protein YP_001674829.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: slo:Shew_2409 short-chain dehydrogenase/reductase SDR YP_001674830.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: slo:Shew_2246 pseudouridine synthase YP_001674831.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB; KEGG: sbm:Shew185_2718 putative transcriptional regulator YP_001674832.1 PFAM: chromosome segregation and condensation protein ScpA; KEGG: slo:Shew_2248 chromosome segregation and condensation protein ScpA YP_001674833.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: slo:Shew_2249 SUA5/YciO/YrdC/YwlC family protein YP_001674834.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: shw:Sputw3181_1606 PHP C-terminal domain protein YP_001674835.1 TIGRFAM: TonB family protein; KEGG: she:Shewmr4_3544 TonB family protein YP_001674837.1 Involved in cell division; probably involved in intracellular septation YP_001674838.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_001674839.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_001674840.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: slo:Shew_2263 methyl-accepting chemotaxis sensory transducer YP_001674841.1 PFAM: protein of unknown function DUF1097; KEGG: son:SO_3047 hypothetical protein YP_001674842.1 PFAM: beta-lactamase domain protein; KEGG: shm:Shewmr7_1500 beta-lactamase domain protein YP_001674843.1 PFAM: alpha/beta hydrolase fold; KEGG: slo:Shew_2270 alpha/beta hydrolase fold YP_001674844.1 KEGG: slo:Shew_2284 hypothetical protein YP_001674845.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_001674846.1 KEGG: vco:VC0395_0697 transcriptional regulator, LysR family YP_001674847.1 PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: sbl:Sbal_0193 methyl-accepting chemotaxis sensory transducer YP_001674848.1 KEGG: slo:Shew_2294 hypothetical protein YP_001674849.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: slo:Shew_2295 transcriptional regulator, AraC family YP_001674850.1 decatenates replicating daughter chromosomes YP_001674851.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001674852.1 PFAM: Colicin V production protein; KEGG: sfr:Sfri_1398 colicin V production protein YP_001674853.1 PFAM: Sporulation domain protein; KEGG: saz:Sama_2148 sporulation related YP_001674854.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: she:Shewmr4_1427 FolC bifunctional protein YP_001674855.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001674856.1 KEGG: sbm:Shew185_2760 hypothetical protein YP_001674857.1 KEGG: slo:Shew_2308 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region YP_001674858.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sbm:Shew185_2762 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region YP_001674859.1 KEGG: mxa:MXAN_5404 hypothetical protein YP_001674860.1 PFAM: ornithine cyclodeaminase/mu-crystallin; KEGG: eca:ECA2039 putative ornithine cyclodeaminase YP_001674861.1 KEGG: eca:ECA2038 hypothetical protein YP_001674862.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: atc:AGR_L_412GM hypothetical protein YP_001674863.1 PFAM: NUDIX hydrolase; KEGG: vha:VIBHAR_06029 hypothetical protein YP_001674864.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: noc:Noc_2021 PAS sensor diguanylate cyclase/phophodiesterase YP_001674865.1 PFAM: ATP-binding region ATPase domain protein; KEGG: vvy:VVA0582 anti-sigma regulatory factor YP_001674866.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: fal:FRAAL1275 positive regulator of sigma-B YP_001674867.1 PFAM: Beta-ketoacyl synthase; KEGG: slo:Shew_2410 beta-ketoacyl synthase YP_001674868.1 PFAM: FAD dependent oxidoreductase; KEGG: shn:Shewana3_1474 FAD dependent oxidoreductase YP_001674869.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: slo:Shew_2412 tRNA/rRNA methyltransferase (SpoU) YP_001674870.1 PFAM: YfcL protein; KEGG: shw:Sputw3181_1560 hypothetical protein YP_001674871.1 PFAM: ATP-NAD/AcoX kinase; KEGG: sbm:Shew185_2767 ATP-NAD/AcoX kinase YP_001674872.1 PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: sbm:Shew185_2768 major facilitator superfamily MFS_1 YP_001674873.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001674874.1 involved in methylation of ribosomal protein L3 YP_001674875.1 PFAM: Smr protein/MutS2; KEGG: slo:Shew_2418 Smr protein/MutS2 YP_001674876.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase; KEGG: she:Shewmr4_1413 phosphohistidine phosphatase, SixA YP_001674877.1 PFAM: peptidase M16 domain protein; KEGG: slo:Shew_2420 peptidase M16 domain protein YP_001674878.1 KEGG: slo:Shew_2421 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; Two component regulator three Y domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001674879.1 KEGG: shw:Sputw3181_1551 hypothetical protein YP_001674880.1 KEGG: sbm:Shew185_2776 hypothetical protein YP_001674881.1 KEGG: slo:Shew_2424 hypothetical protein YP_001674882.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_001674883.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_001674884.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: sbm:Shew185_2782 ATPase associated with various cellular activities AAA_3 YP_001674885.1 PFAM: protein of unknown function DUF58; KEGG: shm:Shewmr7_1470 protein of unknown function DUF58 YP_001674886.1 KEGG: slo:Shew_2429 hypothetical protein YP_001674887.1 PFAM: von Willebrand factor type A; KEGG: son:SO_3093 von Willebrand factor type A domain protein YP_001674888.1 PFAM: TPR repeat-containing protein; von Willebrand factor type A; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: she:Shewmr4_1402 tetratricopeptide TPR_2 repeat protein YP_001674889.1 KEGG: sbm:Shew185_2787 hypothetical protein YP_001674890.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001674891.1 KEGG: slo:Shew_2434 hypothetical protein YP_001674892.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: slo:Shew_2435 sodium/proline symporter YP_001674893.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: slo:Shew_2436 membrane protein involved in aromatic hydrocarbon degradation YP_001674894.1 PFAM: protein of unknown function DUF541; KEGG: shw:Sputw3181_1536 protein of unknown function DUF541 YP_001674895.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sbm:Shew185_2794 efflux transporter, RND family, MFP subunit YP_001674896.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_1458 acriflavin resistance protein YP_001674897.1 KEGG: sbm:Shew185_2796 hypothetical protein YP_001674898.1 PFAM: Rhodanese domain protein; KEGG: shn:Shewana3_1444 rhodanese domain protein YP_001674899.1 KEGG: shw:Sputw3181_2553 hypothetical protein YP_001674900.1 KEGG: sfr:Sfri_2437 hypothetical protein YP_001674901.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_001674902.1 KEGG: sdn:Sden_1446 hypothetical protein YP_001674903.1 TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; KEGG: slo:Shew_2448 anaerobic ribonucleoside-triphosphate reductase activating protein YP_001674904.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_001674905.1 KEGG: sbm:Shew185_1649 hypothetical protein YP_001674906.1 PFAM: Patatin; KEGG: son:SO_2836 hypothetical protein YP_001674907.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: slo:Shew_2452 DEAD/DEAH box helicase domain protein YP_001674908.1 KEGG: slo:Shew_2453 hypothetical protein YP_001674909.1 PFAM: protein of unknown function DUF45; KEGG: son:SO_2840 hypothetical protein YP_001674910.1 KEGG: sbl:Sbal_1657 hypothetical protein YP_001674911.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: pde:Pden_3115 protein of unknown function DUF21 YP_001674912.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; KEGG: pde:Pden_3114 protein of unknown function DUF21 YP_001674913.1 PFAM: 60 kDa inner membrane insertion protein; KEGG: cps:CPS_3020 hypothetical protein YP_001674914.1 PFAM: peptidase M23B; Opacity-associated protein A; KEGG: slo:Shew_2455 peptidase M23B YP_001674915.1 PFAM: SMC domain protein; KEGG: shm:Shewmr7_2519 SMC domain protein YP_001674916.1 TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase; KEGG: sbl:Sbal_1654 nuclease SbcCD, D subunit YP_001674917.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_001674918.1 PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_3526 putative transport YP_001674919.1 KEGG: kpn:KPN_pKPN3p05879 hypothetical protein YP_001674920.1 PFAM: amino acid permease-associated region; KEGG: yen:YE3692 putative amino acid permease YP_001674921.1 catalyzes the formation of glutamate from glutamine YP_001674922.1 PFAM: penicillin-binding protein transpeptidase; KEGG: syn:slr0319 beta-lactamase YP_001674923.1 PFAM: protein of unknown function DUF81; KEGG: pin:Ping_1433 permease with 5 transmembrane domains YP_001674924.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: shw:Sputw3181_2570 transcriptional regulator, LysR family YP_001674925.1 PFAM: NERD domain protein; KEGG: slo:Shew_2466 hypothetical protein YP_001674926.1 PFAM: protein of unknown function DUF1260; KEGG: slo:Shew_2467 protein of unknown function DUF1260 YP_001674927.1 PFAM: RNA-binding S4 domain protein; KEGG: sbm:Shew185_1635 RNA-binding S4 domain protein YP_001674928.1 PFAM: GCN5-related N-acetyltransferase; KEGG: slo:Shew_2469 GCN5-related N-acetyltransferase YP_001674929.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: slo:Shew_2470 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001674930.1 PFAM: protein of unknown function DUF885; KEGG: slo:Shew_2471 protein of unknown function DUF885 YP_001674931.1 PFAM: GGDEF domain containing protein; KEGG: slo:Shew_2472 diguanylate cyclase YP_001674932.1 SMART: Tetratricopeptide domain protein; KEGG: sfr:Sfri_2621 tetratricopeptide domain protein YP_001674933.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: sbm:Shew185_1629 TonB family protein YP_001674934.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: sbm:Shew185_1628 biopolymer transport protein ExbD/TolR YP_001674935.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: sbm:Shew185_1627 MotA/TolQ/ExbB proton channel YP_001674936.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: shn:Shewana3_2625 MotA/TolQ/ExbB proton channel YP_001674937.1 KEGG: saz:Sama_1254 hypothetical protein YP_001674938.1 KEGG: sbm:Shew185_4156 transposase IS4 family protein YP_001674939.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sdn:Sden_2427 TonB-dependent receptor, plug YP_001674940.1 PFAM: porin Gram-negative type; KEGG: slo:Shew_2481 porin, gram-negative type YP_001674941.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95oC YP_001674942.1 helicase involved in DNA repair and perhaps also replication YP_001674943.1 PFAM: protein of unknown function DUF81; KEGG: slo:Shew_2484 protein of unknown function DUF81 YP_001674944.1 KEGG: slo:Shew_2485 primosomal replication protein N'', putative YP_001674945.1 KEGG: sbm:Shew185_1615 hypothetical protein YP_001674946.1 KEGG: shn:Shewana3_2635 hypothetical protein YP_001674947.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: ppr:PBPRA2526 hypothetical protein similar to lipase YP_001674948.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfr:Sfri_3168 major facilitator superfamily MFS_1 YP_001674949.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001674950.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001674951.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_001674952.1 PFAM: MaoC domain protein dehydratase; KEGG: cbe:Cbei_3349 MaoC domain protein dehydratase YP_001674953.1 PFAM: coenzyme A transferase; KEGG: amt:Amet_4532 coenzyme A transferase YP_001674955.1 PFAM: lipase class 2; KEGG: mxa:MXAN_0221 lipase YP_001674956.1 PFAM: alpha/beta hydrolase fold; KEGG: btk:BT9727_3084 3-Oxoadipate enol-lactonase, alpha/beta hydrolase fold family YP_001674957.1 PFAM: alpha/beta hydrolase fold; KEGG: xau:Xaut_0180 alpha/beta hydrolase fold YP_001674958.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ppr:PBPRB1563 hypothetical transcription regulator YP_001674959.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ppr:PBPRB1562 hypothetical 3-oxoacyl-(acyl carrier protein) reductase YP_001674960.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_001674961.1 KEGG: slo:Shew_2489 competence protein ComEA helix-hairpin-helix repeat protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding class 1 YP_001674962.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: slo:Shew_2490 anion transporter YP_001674963.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: saz:Sama_1242 methionine gamma-lyase YP_001674964.1 PFAM: conserved hypothetical protein; KEGG: shm:Shewmr7_2546 conserved hypothetical protein 1620 YP_001674965.1 PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: slo:Shew_2493 protein of unknown function DUF463, YcjX family protein YP_001674966.1 TIGRFAM: shock protein C; PFAM: PspC domain protein; KEGG: slo:Shew_2494 phage shock protein C, PspC YP_001674967.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_001674968.1 TIGRFAM: shock protein A; PFAM: PspA/IM30 family protein; KEGG: slo:Shew_2496 phage shock protein A, PspA YP_001674969.1 KEGG: slo:Shew_2497 sigma54 specific transcriptional regulator, fis family; TIGRFAM: Transcriptional activator PspF; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001674970.1 PFAM: extracellular solute-binding protein family 5; KEGG: shm:Shewmr7_2552 extracellular solute-binding protein, family 5 YP_001674971.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_2499 binding-protein-dependent transport systems inner membrane component YP_001674972.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_2500 binding-protein-dependent transport systems inner membrane component YP_001674973.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; KEGG: shm:Shewmr7_2555 oligopeptide/dipeptide ABC transporter, ATPase subunit YP_001674974.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_2556 ABC transporter related YP_001674975.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_001674976.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: slo:Shew_2504 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001674977.1 PFAM: histone family protein DNA-binding protein; KEGG: slo:Shew_2505 histone family protein DNA-binding protein YP_001674978.1 KEGG: slo:Shew_2506 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16 lon domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001674979.1 binds and unfolds substrates as part of the ClpXP protease YP_001674980.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001674981.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001674982.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001674983.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001674984.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: slo:Shew_2512 peptidylprolyl isomerase YP_001674985.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_001674986.1 PFAM: protein of unknown function DUF1282; KEGG: sbl:Sbal_1597 protein of unknown function DUF1282 YP_001674987.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001674988.1 TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; nucleoside recognition domain protein; KEGG: slo:Shew_2517 ferrous iron transport protein B YP_001674989.1 PFAM: FeoA family protein; KEGG: shw:Sputw3181_2621 FeoA family protein YP_001674990.1 TIGRFAM: cytochrome C family protein; PFAM: multihaem cytochrome; KEGG: slo:Shew_2519 cytochrome c family protein YP_001674991.1 KEGG: slo:Shew_2520 outer membrane protein, putative YP_001674992.1 KEGG: slo:Shew_2521 decaheme cytochrome c MtrF YP_001674993.1 KEGG: slo:Shew_2522 decaheme cytochrome c YP_001674994.1 KEGG: spc:Sputcn32_1479 hypothetical protein YP_001674995.1 KEGG: slo:Shew_2524 decaheme cytochrome c YP_001674996.1 KEGG: sfr:Sfri_2637 decaheme cytochrome c YP_001674997.1 TIGRFAM: cytochrome C family protein; PFAM: multihaem cytochrome; KEGG: slo:Shew_2526 cytochrome c family protein YP_001674998.1 KEGG: slo:Shew_2527 outer membrane protein precursor MtrB YP_001674999.1 KEGG: sbl:Sbal_1586 hypothetical protein YP_001675000.1 KEGG: saz:Sama_1203 hypothetical protein YP_001675001.1 PFAM: sugar diacid recognition domain protein; KEGG: slo:Shew_2528 transcriptional regulator, CdaR YP_001675002.1 KEGG: vch:VC0502 type IV pilin, putative YP_001675003.1 PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: vpa:VPA0248 putative outer membrane protein OmpA YP_001675004.1 KEGG: vha:VIBHAR_07131 hypothetical protein YP_001675005.1 KEGG: shm:Shewmr7_2311 hypothetical protein YP_001675006.1 KEGG: sbm:Shew185_0590 P pilus assembly protein porin PapC-like protein YP_001675009.1 KEGG: vha:VIBHAR_05990 hypothetical protein YP_001675010.1 KEGG: vha:VIBHAR_02615 hypothetical protein YP_001675011.1 PFAM: Gluconate transporter; Citrate transporter; KEGG: slo:Shew_2533 gluconate transporter YP_001675012.1 PFAM: glycerate kinase; KEGG: slo:Shew_2534 glycerate kinase YP_001675013.1 PFAM: Pyridoxal-dependent decarboxylase; KEGG: slo:Shew_2535 pyridoxal-dependent decarboxylase YP_001675014.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: slo:Shew_2370 methyltransferase type 11 YP_001675015.1 KEGG: tdn:Tmden_0652 hypothetical protein YP_001675017.1 KEGG: mmw:Mmwyl1_1032 hypothetical protein YP_001675018.1 PFAM: Lytic transglycosylase catalytic; KEGG: pha:PSHAb0242 putative transglycosylase YP_001675019.1 KEGG: vfi:VFA0327 hypothetical protein YP_001675020.1 KEGG: pha:PSHAb0243 putative orphan protein YP_001675021.1 PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: son:SO_1755 phosphoglucomutase/phosphomannomutase family protein YP_001675022.1 PFAM: pseudouridine synthase; KEGG: sfr:Sfri_0787 pseudouridine synthase YP_001675023.1 PFAM: cytochrome B561; KEGG: slo:Shew_2692 cytochrome b561 YP_001675024.1 PFAM: Glutathione S-transferase domain; KEGG: sfr:Sfri_2500 glutathione S-transferase, C-terminal domain protein YP_001675025.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sfr:Sfri_2100 MscS mechanosensitive ion channel YP_001675026.1 KEGG: rxy:Rxyl_2652 hypothetical protein YP_001675027.1 KEGG: saz:Sama_1098 hypothetical protein YP_001675028.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ppr:PBPRA1465 steroid dehydrogenase YP_001675029.1 Catalyzes the specific recognition and activation of amino acids during peptide synthesis YP_001675030.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO_1743 hydrolase, alpha/beta hydrolase fold family YP_001675031.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001675032.1 KEGG: spc:Sputcn32_1444 hypothetical protein YP_001675033.1 KEGG: slo:Shew_1711 conserved hypothetical methyl-accepting chemotaxis protein YP_001675034.1 PFAM: protein of unknown function DUF1289; KEGG: sfr:Sfri_1363 protein of unknown function DUF1289 YP_001675035.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: slo:Shew_1709 HNH nuclease YP_001675036.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: shw:Sputw3181_2658 choline/carnitine/betaine transporter YP_001675037.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_001675038.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001675039.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_1699 phosphate ABC transporter, inner membrane subunit PstA YP_001675040.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_1698 binding-protein-dependent transport systems inner membrane component YP_001675041.1 PFAM: amino acid-binding ACT domain protein; KEGG: slo:Shew_1697 amino acid-binding ACT domain protein YP_001675042.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: nis:NIS_1660 signal transduction response regulator YP_001675043.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001675044.1 PFAM: regulatory protein TetR; KEGG: asa:ASA_3408 transcriptional regulator, TetR family YP_001675045.1 PFAM: Xanthine/uracil/vitamin C permease; KEGG: aha:AHA_0949 xanthine/uracil permease family protein YP_001675046.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type YP_001675047.1 KEGG: she:Shewmr4_2564 hypothetical protein YP_001675048.1 KEGG: saz:Sama_1395 hypothetical protein YP_001675049.1 KEGG: shn:Shewana3_2741 hypothetical protein YP_001675050.1 PFAM: Thrombospondin type 3 repeat; peptidase domain protein; Peptidase M9A collagenase domain protein; Peptidase M9 domain; KEGG: slo:Shew_1685 microbial collagenase YP_001675051.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: slo:Shew_1684 lysine exporter protein (LysE/YggA) YP_001675052.1 PFAM: protein of unknown function DUF1415; KEGG: shw:Sputw3181_2672 protein of unknown function DUF1415 YP_001675053.1 PFAM: ribonuclease H; KEGG: sfr:Sfri_3175 ribonuclease H YP_001675054.1 KEGG: slo:Shew_1678 hypothetical protein YP_001675055.1 PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: slo:Shew_1677 leucyl aminopeptidase YP_001675056.1 PFAM: ApbE family lipoprotein; KEGG: sdn:Sden_0988 ApbE-like lipoprotein YP_001675057.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FMN-binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO_4620 fumarate reductase, flavoprotein subunit precursor YP_001675058.1 KEGG: shn:Shewana3_4005 hypothetical protein YP_001675059.1 KEGG: shn:Shewana3_4006 histidine kinase A domain protein domain protein YP_001675060.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO_4623 DNA-binding response regulator YP_001675061.1 PFAM: regulatory protein LuxR; KEGG: son:SO_4624 transcriptional regulator, LuxR family YP_001675062.1 KEGG: slo:Shew_0274 hypothetical protein YP_001675063.1 PFAM: Modulator of Rho-dependent transcription termination; KEGG: vco:VC0395_0290 hypothetical protein YP_001675064.1 KEGG: tcx:Tcr_1988 hypothetical protein YP_001675065.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: ppr:PBPRB1458 putative NupC family protein (permease) YP_001675066.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: vfi:VFA0483 rod shape-determining protein RodA YP_001675067.1 PFAM: UspA domain protein; KEGG: vch:VCA0159 hypothetical protein YP_001675068.1 KEGG: vha:VIBHAR_06882 hypothetical protein YP_001675069.1 KEGG: vvu:VV2_0955 hypothetical protein YP_001675070.1 KEGG: pmy:Pmen_1369 beta-lactamase domain protein YP_001675071.1 PFAM: regulatory protein LysR; KEGG: vvu:VV2_0953 transcriptional regulator YP_001675072.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: syn:sll0644 esterase YP_001675073.1 PFAM: sulfatase; protein of unknown function DUF1705; KEGG: vvu:VV2_1411 predicted membrane-associated metal-dependent hydrolase YP_001675074.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_1676 ABC transporter-related protein YP_001675075.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: shn:Shewana3_2761 copper-translocating P-type ATPase YP_001675076.1 PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: son:SO_1687 transcriptional regulator, MerR family YP_001675077.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: sbl:Sbal_1503 peptidase S9, prolyl oligopeptidase active site domain protein YP_001675078.1 KEGG: shm:Shewmr7_2657 hypothetical protein YP_001675080.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001675081.1 KEGG: slo:Shew_1672 3-hydroxyisobutyrate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding YP_001675082.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: slo:Shew_1671 enoyl-CoA hydratase/isomerase YP_001675083.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001675084.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: sbm:Shew185_1491 acyl-CoA dehydrogenase domain protein YP_001675085.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: spc:Sputcn32_1398 methylmalonate-semialdehyde dehydrogenase YP_001675086.1 KEGG: sdn:Sden_1943 acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001675087.1 PFAM: regulatory protein LuxR; KEGG: vvu:VV1_2744 response regulator YP_001675088.1 KEGG: vvy:VV1518 hypothetical protein YP_001675089.1 KEGG: vvy:VV1519 P pilus assembly protein, chaperone PapD YP_001675090.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: vvy:VV1520 P pilus assembly protein, porin PapC YP_001675091.1 KEGG: vvy:VV1521 hypothetical protein YP_001675092.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_001675093.1 KEGG: slo:Shew_2552 hypothetical protein YP_001675094.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: shw:Sputw3181_2708 short-chain dehydrogenase/reductase SDR YP_001675095.1 receptor for colicin S4 YP_001675096.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: shn:Shewana3_0372 efflux transporter, RND family, MFP subunit YP_001675097.1 PFAM: acriflavin resistance protein; KEGG: shn:Shewana3_0371 acriflavin resistance protein YP_001675098.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: vfi:VFA0024 transcriptional regulators, LysR family YP_001675099.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: vfi:VFA0023 enoyl-CoA hydratase YP_001675100.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: swo:Swol_0919 oxygen-independent coproporphyrinogen III oxidase, Fe-S oxidoreductase YP_001675102.1 PFAM: protein of unknown function DUF925; KEGG: shm:Shewmr7_2669 protein of unknown function DUF925 YP_001675103.1 KEGG: shn:Shewana3_1689 hypothetical protein YP_001675104.1 KEGG: slo:Shew_2556 acyl-CoA thioesterase II; TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase YP_001675105.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: slo:Shew_2557 short-chain dehydrogenase/reductase SDR YP_001675106.1 TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; KEGG: slo:Shew_2558 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_001675107.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001675108.1 PFAM: AMP-dependent synthetase and ligase; KEGG: sbm:Shew185_2844 AMP-dependent synthetase and ligase YP_001675109.1 PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: slo:Shew_2569 transcriptional regulator, MerR family YP_001675110.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: slo:Shew_2570 acyl-CoA dehydrogenase domain protein YP_001675111.1 PFAM: carboxyl transferase; KEGG: sdn:Sden_2246 propionyl-CoA carboxylase YP_001675112.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: slo:Shew_2572 enoyl-CoA hydratase/isomerase YP_001675113.1 PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: slo:Shew_2573 carbamoyl-phosphate synthase L chain, ATP-binding YP_001675114.1 KEGG: slo:Shew_2573 carbamoyl-phosphate synthase L chain, ATP-binding YP_001675115.1 PFAM: pyruvate carboxyltransferase; KEGG: slo:Shew_2574 pyruvate carboxyltransferase YP_001675116.1 KEGG: slo:Shew_2575 3-oxoacid CoA-transferase, A subunit; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001675117.1 KEGG: slo:Shew_2576 3-oxoacid CoA-transferase, B subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001675118.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: shw:Sputw3181_4067 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family YP_001675119.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: rso:RSp0313 probable multidrug efflux system protein YP_001675120.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pfl:PFL_5111 DNA-binding response regulator ColR, putative YP_001675121.1 PFAM: histidine kinase A domain protein; KEGG: sfr:Sfri_3675 periplasmic sensor signal transduction histidine kinase YP_001675122.1 KEGG: vfi:VF1339 hypothetical protein YP_001675123.1 PFAM: alpha/beta hydrolase fold; KEGG: sbm:Shew185_3419 alpha/beta hydrolase fold YP_001675124.1 PFAM: beta-lactamase domain protein; KEGG: son:SO_1606 metallo-beta-lactamase superfamily protein YP_001675125.1 KEGG: sbm:Shew185_0872 hypothetical protein YP_001675126.1 PFAM: cytochrome c552; KEGG: shn:Shewana3_0658 cytochrome c552 YP_001675127.1 KEGG: sdn:Sden_2534 hypothetical protein YP_001675128.1 PFAM: cytochrome c552; KEGG: shm:Shewmr7_3363 nitrite reductase (cytochrome; ammonia-forming) YP_001675129.1 KEGG: sdn:Sden_2534 hypothetical protein YP_001675130.1 PFAM: Endoribonuclease L-PSP; KEGG: vfi:VFA0365 translation initiation inhibitor YP_001675131.1 KEGG: spc:Sputcn32_0630 hypothetical protein YP_001675132.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: sfr:Sfri_3126 cytoplasmic chaperone TorD family protein YP_001675133.1 TIGRFAM: Dimethylsulfoxide reductase chain B; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfr:Sfri_3683 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001675134.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: son:SO_1429 anaerobic dimethyl sulfoxide reductase, A subunit YP_001675135.1 KEGG: sfr:Sfri_3685 outer membrane protein YP_001675136.1 TIGRFAM: cytochrome C family protein; PFAM: multihaem cytochrome; KEGG: sfr:Sfri_3686 cytochrome c family protein YP_001675137.1 KEGG: cps:CPS_0255 isoprenylcysteine carboxyl methyltransferase family protein YP_001675138.1 PFAM: protein of unknown function DUF1176; protein of unknown function DUF1311; KEGG: pcr:Pcryo_1380 protein of unknown function DUF1176 YP_001675142.1 KEGG: bam:Bamb_3528 hypothetical protein YP_001675144.1 PFAM: protein of unknown function DUF1568; KEGG: sdn:Sden_0135 protein of unknown function DUF1568 YP_001675146.1 PFAM: LemA family protein; KEGG: ilo:IL1567 uncharacterized conserved membrane protein, LemA family YP_001675147.1 KEGG: ilo:IL1568 predicted membrane protein YP_001675148.1 KEGG: pfl:PFL_1944 hypothetical protein YP_001675149.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_001675150.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: she:Shewmr4_1355 peptidyl-dipeptidase DCP YP_001675151.1 PFAM: Na+/H+ antiporter NhaC; KEGG: slo:Shew_2582 Na+/H+ antiporter NhaC YP_001675152.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit ; Electron transfer flavoprotein alpha subunit; KEGG: slo:Shew_2583 electron transfer flavoprotein, alpha subunit YP_001675153.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: slo:Shew_2584 electron transfer flavoprotein beta-subunit YP_001675154.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: sbm:Shew185_2867 histone family protein nucleoid-structuring protein H-NS YP_001675155.1 PFAM: amidohydrolase; KEGG: slo:Shew_2586 amidohydrolase YP_001675156.1 KEGG: slo:Shew_2587 hypothetical protein YP_001675157.1 KEGG: shw:Sputw3181_1493 lipoprotein, putative YP_001675158.1 PFAM: protein of unknown function UPF0066; KEGG: sfr:Sfri_2751 protein of unknown function UPF0066 YP_001675159.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: shw:Sputw3181_1491 transferase hexapeptide repeat containing protein YP_001675160.1 PFAM: amino acid permease-associated region; KEGG: lin:lin2462 hypothetical protein YP_001675161.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: hch:HCH_06121 transcriptional regulator YP_001675162.1 KEGG: cps:CPS_3603 hypothetical protein YP_001675163.1 KEGG: cps:CPS_3591 3-oxoadipate CoA-transferase, alpha subunit; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001675164.1 KEGG: cps:CPS_3592 3-oxoadipate CoA-transferase, beta subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001675165.1 PFAM: aminotransferase class-III; KEGG: cps:CPS_3593 putative glutamate-1-semialdehyde-2,1-aminomutase YP_001675166.1 TIGRFAM: acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase; PFAM: Thiolase; KEGG: cps:CPS_3594 beta-ketoadipyl CoA thiolase YP_001675167.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: pol:Bpro_3376 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001675168.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001675169.1 PFAM: Patatin; KEGG: saz:Sama_1160 hypothetical protein YP_001675170.1 KEGG: ppr:PBPRB1925 hypothetical protein YP_001675171.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; sodium/hydrogen exchanger; KEGG: slo:Shew_2617 potassium efflux system protein YP_001675172.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sbl:Sbal_1467 diguanylate cyclase YP_001675173.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; Protein of unkown function DUF1946 PP-loop ATpase; KEGG: shn:Shewana3_2799 tRNA(Ile)-lysidine synthetase YP_001675174.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001675175.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001675176.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001675177.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001675178.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001675179.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001675180.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: slo:Shew_2626 outer membrane chaperone Skp (OmpH) YP_001675181.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: shm:Shewmr7_2700 surface antigen (D15) YP_001675182.1 KEGG: son:SO_1636 membrane-associated zinc metalloprotease, putative; TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein YP_001675183.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001675184.1 PFAM: phosphatidate cytidylyltransferase; KEGG: saz:Sama_1144 phosphatidate cytidylyltransferase YP_001675185.1 KEGG: sbm:Shew185_1449 undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_001675186.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001675187.1 Catalyzes the phosphorylation of UMP to UDP YP_001675188.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001675189.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001675190.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001675191.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001675192.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001675193.1 KEGG: shn:Shewana3_2819 hypothetical protein YP_001675194.1 TIGRFAM: formyltetrahydrofolate deformylase; PFAM: formyl transferase domain protein; amino acid-binding ACT domain protein; KEGG: sfr:Sfri_1265 formyltetrahydrofolate deformylase YP_001675195.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001675196.1 PFAM: pseudouridine synthase; KEGG: slo:Shew_2643 pseudouridylate synthase YP_001675197.1 PFAM: protein of unknown function DUF446; KEGG: son:SO_1619 hypothetical protein YP_001675198.1 KEGG: shn:Shewana3_2826 hypothetical protein YP_001675199.1 KEGG: slo:Shew_2646 hypothetical protein YP_001675200.1 KEGG: pmy:Pmen_1824 membrane protein-like protein YP_001675201.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_2722 GCN5-related N-acetyltransferase YP_001675202.1 KEGG: slo:Shew_2649 hypothetical protein YP_001675203.1 KEGG: sbm:Shew185_1429 hypothetical protein YP_001675204.1 KEGG: slo:Shew_2651 hypothetical protein YP_001675205.1 KEGG: slo:Shew_2652 hypothetical protein YP_001675206.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_001675207.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_001675209.1 KEGG: vfi:VF0867 hypothetical protein YP_001675210.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: son:SO_1607 transcriptional regulator, LysR family YP_001675211.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbl:Sbal_1430 transcriptional regulator, LysR family YP_001675212.1 PFAM: beta-lactamase domain protein; KEGG: sbl:Sbal_1429 beta-lactamase domain protein YP_001675213.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: sbm:Shew185_1421 4'-phosphopantetheinyl transferase YP_001675214.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001675215.1 KEGG: slo:Shew_2664 transcriptional regulator, putative YP_001675216.1 KEGG: slo:Shew_2665 beta-ketoacyl synthase; TIGRFAM: Polyketide-type polyunsaturated fatty acid synthase, PfaA; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR domain protein; Beta-ketoacyl synthase ; Acyl transferase YP_001675217.1 TIGRFAM: PfaB family protein; KEGG: ppr:PBPRA1459 omega-3 polyunsaturated fatty acid synthase PfaB YP_001675218.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; Beta-ketoacyl synthase; KEGG: slo:Shew_2667 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ YP_001675219.1 TIGRFAM: PfaD family protein; KEGG: slo:Shew_2668 2-nitropropane dioxygenase, NPD YP_001675221.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; CHASE4 domain protein; KEGG: sdn:Sden_1662 GGDEF domain YP_001675222.1 KEGG: shm:Shewmr7_0435 methylation site containing protein YP_001675223.1 PFAM: peptidase S45 penicillin amidase; KEGG: slo:Shew_2669 penicillin amidase YP_001675224.1 KEGG: vha:VIBHAR_05811 hypothetical protein YP_001675225.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: vfi:VF1790 ATP-dependent RNA helicase YP_001675226.1 KEGG: sfr:Sfri_0530 hypothetical protein YP_001675227.1 KEGG: sfr:Sfri_3605 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001675228.1 TIGRFAM: TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: son:SO_0719 TonB-dependent receptor, putative YP_001675229.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: cps:CPS_1347 TonB-dependent receptor YP_001675230.1 KEGG: shm:Shewmr7_3906 hypothetical protein YP_001675231.1 PFAM: Propeptide PepSY amd peptidase M4; KEGG: slo:Shew_2694 propeptide, PepSY amd peptidase M4 YP_001675232.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO_4647 DNA-binding response regulator YP_001675233.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; KEGG: pin:Ping_0281 sensor histidine kinase with ATPase domain YP_001675234.1 KEGG: slo:Shew_2697 hypothetical protein YP_001675235.1 SMART: tyrosine protein kinase; serine/threonine protein kinase; leucine-rich repeat-containing protein typical subtype; KEGG: shm:Shewmr7_0539 serine/threonine protein kinase YP_001675236.1 PFAM: protein of unknown function DUF599; KEGG: slo:Shew_2715 protein of unknown function DUF599 YP_001675237.1 KEGG: slo:Shew_2719 hypothetical protein YP_001675238.1 KEGG: shm:Shewmr7_2754 hypothetical protein YP_001675239.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_0630 conserved hypothetical protein 245 YP_001675240.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001675241.1 KEGG: sfr:Sfri_3204 nucleoside-diphosphate-sugar epimerase YP_001675242.1 PFAM: protein of unknown function DUF633; KEGG: sbm:Shew185_2328 hypothetical protein YP_001675243.1 PFAM: NUDIX hydrolase; KEGG: slo:Shew_2723 NUDIX hydrolase YP_001675244.1 KEGG: sde:Sde_0094 hypothetical protein YP_001675245.1 PFAM: sodium/glutamate symporter; KEGG: psa:PST_0687 sodium-glutamate symporter YP_001675246.1 PFAM: sodium:dicarboxylate symporter; KEGG: shw:Sputw3181_3503 sodium:dicarboxylate symporter YP_001675247.1 PFAM: Indigoidine synthase A family protein; KEGG: slo:Shew_2724 indigoidine synthase A family protein YP_001675248.1 PFAM: PfkB domain protein; Helix-turn-helix type 11 domain protein; KEGG: slo:Shew_2725 PfkB domain protein YP_001675249.1 TIGRFAM: YidE/YbjL duplication; PFAM: YidE/YbjL duplication domain protein; KEGG: vfi:VF1065 integral membrane protein with TrkA domains YP_001675250.1 TIGRFAM: glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; KEGG: vfi:VF1064 glutamate decarboxylase YP_001675251.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: sdn:Sden_2795 antibiotic biosynthesis monooxygenase YP_001675252.1 KEGG: cps:CPS_3943 hypothetical protein YP_001675253.1 PFAM: protein of unknown function DUF188; KEGG: slo:Shew_2726 protein of unknown function DUF188 YP_001675254.1 PFAM: conserved hypothetical protein; KEGG: sbl:Sbal_1396 hypothetical protein YP_001675255.1 PFAM: Fmu (Sun) domain protein; KEGG: sfr:Sfri_1209 Fmu (Sun) domain protein YP_001675256.1 PFAM: YfaZ family protein; KEGG: slo:Shew_2740 YfaZ family protein YP_001675257.1 KEGG: slo:Shew_3409 putative lipoprotein YP_001675258.1 PFAM: glutathione peroxidase; KEGG: sfr:Sfri_2764 glutathione peroxidase YP_001675259.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001675260.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_001675261.1 KEGG: ppr:PBPRA0992 hypothetical transcriptional regulator YP_001675262.1 PFAM: Peptidase M1 membrane alanine aminopeptidase ; Leukotriene A4 hydrolase; KEGG: slo:Shew_2742 peptidase M1, membrane alanine aminopeptidase YP_001675263.1 PFAM: Peptidase M9A collagenase domain protein; KEGG: slo:Shew_2743 microbial collagenase YP_001675264.1 TIGRFAM: phosphate binding protein; KEGG: slo:Shew_2747 phosphate binding protein YP_001675265.1 KEGG: son:SO_1559 phosphate regulon sensor protein PhoR; TIGRFAM: Phosphate regulon sensor kinase PhoR; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001675266.1 TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: slo:Shew_2749 two component transcriptional regulator, winged helix family YP_001675267.1 PFAM: porin Gram-negative type; KEGG: slo:Shew_2750 porin, gram-negative type YP_001675268.1 Required for efficient pilin antigenic variation YP_001675269.1 PFAM: peptidase M61 domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: sbm:Shew185_1361 peptidase M61 domain protein YP_001675270.1 SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_2781 TPR repeat-containing protein YP_001675271.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sbm:Shew185_1359 diguanylate cyclase YP_001675272.1 PFAM: conserved hypothetical protein; KEGG: sdn:Sden_2557 conserved hypothetical protein 730 YP_001675273.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_001675274.1 KEGG: slo:Shew_2757 hypothetical protein YP_001675275.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: slo:Shew_2759 peptidase S9, prolyl oligopeptidase active site domain protein YP_001675276.1 catalyzes the formation of 2-oxoglutarate from isocitrate YP_001675277.1 KEGG: slo:Shew_2761 hypothetical protein YP_001675278.1 PFAM: protein of unknown function DUF423; KEGG: slo:Shew_2762 protein of unknown function DUF423 YP_001675279.1 KEGG: slo:Shew_2763 dienelactone hydrolase YP_001675280.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_001675281.1 KEGG: slo:Shew_2765 hypothetical protein YP_001675282.1 Required for the synthesis of the thiazole moiety YP_001675283.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; Vibrio parahaemolyticus protein is associated with the polar flagella YP_001675284.1 Homologous to MotA in E. coli and Salmonella. With PomB forms the ion channels that couple flagellar rotation to sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. YP_001675285.1 TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII small subunit; KEGG: sbl:Sbal_1359 exodeoxyribonuclease VII, small subunit YP_001675286.1 PFAM: Polyprenyl synthetase; KEGG: slo:Shew_2770 polyprenyl synthetase YP_001675287.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001675288.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001675289.1 catalyzes the phosphorylation of NAD to NADP YP_001675290.1 PFAM: L-lactate permease; KEGG: slo:Shew_3135 L-lactate permease YP_001675291.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; FAD linked oxidase domain protein; KEGG: shn:Shewana3_2905 FAD linked oxidase domain protein YP_001675292.1 PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: slo:Shew_3004 protein of unknown function DUF224, cysteine-rich region domain protein YP_001675293.1 PFAM: protein of unknown function DUF162; KEGG: slo:Shew_3005 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001675294.1 PFAM: protein of unknown function DUF162; KEGG: shm:Shewmr7_2816 protein of unknown function DUF162 YP_001675295.1 TIGRFAM: TonB family protein; KEGG: spc:Sputcn32_0632 TonB family protein YP_001675296.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO_1506 MATE efflux family protein YP_001675297.1 PFAM: cobalamin synthesis protein P47K; KEGG: spc:Sputcn32_1255 cobalamin synthesis protein, P47K YP_001675298.1 KEGG: gsu:GSU0757 lipoprotein, putative YP_001675299.1 KEGG: cps:CPS_2486 hypothetical protein YP_001675300.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: shw:Sputw3181_2850 DEAD/DEAH box helicase domain protein YP_001675301.1 KEGG: slo:Shew_2778 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001675302.1 PFAM: OsmC family protein; KEGG: shn:Shewana3_1075 OsmC family protein YP_001675303.1 PFAM: thioesterase superfamily protein; KEGG: slo:Shew_2780 thioesterase superfamily protein YP_001675304.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: spc:Sputcn32_2800 diguanylate cyclase/phosphodiesterase YP_001675305.1 PFAM: Metal-dependent hydrolase HDOD; KEGG: saz:Sama_1005 putative signal transduction protein YP_001675306.1 PFAM: peptidase U32; KEGG: sfr:Sfri_1022 peptidase U32 YP_001675307.1 PFAM: Carbohydrate-selective porin OprB; KEGG: cps:CPS_0267 hypothetical protein YP_001675308.1 KEGG: vha:VIBHAR_05705 hypothetical protein YP_001675309.1 KEGG: vha:VIBHAR_06184 hypothetical protein YP_001675310.1 KEGG: slo:Shew_0983 amidohydrolase YP_001675311.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ppr:PBPRB0224 hypothetical protein YP_001675312.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: slo:Shew_2785 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001675313.1 PFAM: pseudouridine synthase; KEGG: slo:Shew_2529 pseudouridine synthase YP_001675314.1 PFAM: Sterol-binding domain protein; KEGG: shm:Shewmr7_1134 sterol-binding domain protein YP_001675315.1 PFAM: peptidase U32; KEGG: slo:Shew_2787 peptidase U32 YP_001675316.1 PFAM: peptidase U32; KEGG: slo:Shew_2788 peptidase U32 YP_001675317.1 TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sfr:Sfri_3427 alcohol dehydrogenase GroES domain protein YP_001675318.1 KEGG: shn:Shewana3_1063 hypothetical protein YP_001675319.1 KEGG: shw:Sputw3181_2968 methyl-accepting chemotaxis sensory transducer YP_001675320.1 PFAM: nucleoside recognition domain protein; KEGG: slo:Shew_2790 nucleoside recognition domain protein YP_001675321.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: slo:Shew_2795 xanthine/uracil/vitamin C permease YP_001675322.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: sbl:Sbal_1252 DEAD/DEAH box helicase domain protein YP_001675323.1 KEGG: vfi:VF2363 glyceraldehyde 3-phosphate dehydrogenase YP_001675324.1 KEGG: vvy:VVA1400 hypothetical protein YP_001675325.1 PFAM: type IV pilus assembly PilZ; KEGG: saz:Sama_0982 hypothetical protein YP_001675326.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001675327.1 PFAM: type IV pilus assembly PilZ; KEGG: slo:Shew_2808 type IV pilus assembly PilZ YP_001675328.1 KEGG: vco:VC0395_A1179 hypothetical protein YP_001675329.1 PFAM: SNARE associated Golgi protein; KEGG: vfi:VFA0471 DedA family protein YP_001675330.1 PFAM: sulfatase; KEGG: shw:Sputw3181_0059 sulfatase YP_001675331.1 PFAM: Polysulphide reductase NrfD; KEGG: shm:Shewmr7_0509 polysulphide reductase, NrfD YP_001675332.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: shn:Shewana3_3618 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001675333.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: sbm:Shew185_0531 molybdopterin oxidoreductase YP_001675334.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: shn:Shewana3_3696 ATP-binding region, ATPase domain protein domain protein YP_001675335.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: shw:Sputw3181_3638 response regulator receiver protein YP_001675336.1 KEGG: she:Shewmr4_1043 alpha/beta hydrolase fold YP_001675337.1 KEGG: sbm:Shew185_3223 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase YP_001675338.1 KEGG: she:Shewmr4_1041 membrane protein YP_001675339.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_001675340.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_001675341.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_001675342.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001675343.1 PFAM: nucleoside-specific channel-forming protein Tsx; KEGG: son:SO_1215 outer membrane protein OmpK, putative YP_001675344.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: sbm:Shew185_3232 nucleoside transporter YP_001675345.1 PFAM: TatD-related deoxyribonuclease; KEGG: saz:Sama_0970 TatD-related deoxyribonuclease YP_001675346.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001675347.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_001675348.1 KEGG: slo:Shew_2822 polyribonucleotide nucleotidyltransferase; PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH type 1 domain protein; Exoribonuclease, phosphorolytic domain 2; Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; SMART: KH domain protein YP_001675349.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase HAMP region domain protein; KEGG: sbm:Shew185_3276 diguanylate cyclase/phosphodiesterase YP_001675350.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001675351.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001675352.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001675353.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001675354.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001675355.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001675356.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: slo:Shew_2830 preprotein translocase, SecG subunit YP_001675357.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001675358.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001675359.1 KEGG: shm:Shewmr7_1085 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS YP_001675360.1 KEGG: slo:Shew_2834 ATP-dependent metalloprotease FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase central domain protein; peptidase M41 FtsH extracellular; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001675361.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_001675362.1 PFAM: protein of unknown function UPF0044; KEGG: slo:Shew_2836 protein of unknown function UPF0044 YP_001675363.1 TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF; PFAM: SecD/SecF/SecDF export membrane protein; KEGG: sbm:Shew185_3291 protein-export membrane protein SecF YP_001675364.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001675365.1 KEGG: sfr:Sfri_0978 hypothetical protein YP_001675366.1 TIGRFAM: transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: shn:Shewana3_1017 transcription elongation factor GreA YP_001675367.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001675368.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001675369.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001675370.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: slo:Shew_2841 peptidylprolyl isomerase, FKBP-type YP_001675371.1 PFAM: peptidase M48 Ste24p; KEGG: shn:Shewana3_0964 peptidase M48, Ste24p YP_001675372.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001675373.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001675374.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: slo:Shew_2845 protein of unknown function DUF6, transmembrane YP_001675375.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001675376.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001675377.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: saz:Sama_2517 xanthine/uracil permease family protein YP_001675378.1 PFAM: pentapeptide repeat protein; KEGG: vpa:VPA1301 hypothetical protein YP_001675379.1 PFAM: protein of unknown function DUF1568; KEGG: sdn:Sden_0135 protein of unknown function DUF1568 YP_001675380.1 KEGG: shw:Sputw3181_3220 hypothetical protein YP_001675381.1 KEGG: slo:Shew_2852 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001675382.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001675384.1 TIGRFAM: bacterioferritin; PFAM: Ferritin Dps family protein; KEGG: slo:Shew_2872 bacterioferritin YP_001675385.1 TIGRFAM: bacterioferritin; PFAM: Ferritin Dps family protein; KEGG: sdn:Sden_0990 bacterioferritin YP_001675386.1 PFAM: protein of unknown function DUF539; KEGG: slo:Shew_2874 protein of unknown function DUF539 YP_001675387.1 PFAM: ApbE family lipoprotein; KEGG: sbm:Shew185_3432 ApbE family lipoprotein YP_001675388.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001675389.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_001675390.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_001675391.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001675392.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001675393.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001675394.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_001675395.1 PFAM: BolA family protein; KEGG: slo:Shew_2883 BolA family protein YP_001675396.1 KEGG: slo:Shew_2885 2OG-Fe(II) oxygenase YP_001675397.1 PFAM: methyltransferase small; KEGG: shw:Sputw3181_3242 rRNA (guanine-N(2)-)-methyltransferase YP_001675398.1 KEGG: shw:Sputw3181_3349 hypothetical protein YP_001675399.1 KEGG: shm:Shewmr7_0816 OmpA domain protein transmembrane region-containing protein YP_001675400.1 PFAM: Uncharacterized lipoprotein; KEGG: slo:Shew_2889 uncharacterized lipoprotein YP_001675401.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: sfr:Sfri_3112 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001675402.1 KEGG: slo:Shew_2891 hypothetical protein YP_001675403.1 PFAM: major facilitator superfamily MFS_1; KEGG: slo:Shew_2892 major facilitator superfamily MFS_1 YP_001675404.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001675405.1 PFAM: VanZ family protein; KEGG: shw:Sputw3181_3356 VanZ family protein YP_001675406.1 KEGG: slo:Shew_2895 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE domain protein YP_001675407.1 PFAM: sodium:neurotransmitter symporter; KEGG: ppr:PBPRA1510 putative sodium-dependent transporter YP_001675409.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: slo:Shew_2901 phosphoesterase, PA-phosphatase related YP_001675411.1 PFAM: C4-dicarboxylate anaerobic carrier; AbgT putative transporter; short chain fatty acid transporter; KEGG: saz:Sama_3423 transporter YP_001675412.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001675413.1 PFAM: protein of unknown function DUF819; KEGG: slo:Shew_2905 protein of unknown function DUF819 YP_001675414.1 KEGG: slo:Shew_2906 hypothetical protein YP_001675415.1 PFAM: Invasion gene expression up-regulator SirB; KEGG: son:SO_3830 hypothetical protein YP_001675416.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: slo:Shew_2911 modification methylase, HemK family YP_001675417.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001675418.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001675419.1 PFAM: outer membrane lipoprotein LolB; KEGG: she:Shewmr4_3171 outer membrane lipoprotein LolB YP_001675420.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001675421.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001675422.1 KEGG: slo:Shew_2917 hypothetical protein YP_001675423.1 KEGG: slo:Shew_2918 hypothetical protein YP_001675424.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001675425.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001675426.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: slo:Shew_2921 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family YP_001675427.1 KEGG: sbm:Shew185_3302 hypothetical protein YP_001675428.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001675429.1 PFAM: PhoH family protein; KEGG: slo:Shew_2924 PhoH family protein YP_001675430.1 PFAM: protein of unknown function UPF0054; KEGG: sdn:Sden_0813 protein of unknown function UPF0054 YP_001675431.1 PFAM: CBS domain containing protein; transporter-associated region; KEGG: slo:Shew_2926 CBS domain containing protein YP_001675432.1 Transfers the fatty acyl group on membrane lipoproteins YP_001675433.1 PFAM: protein of unknown function DUF1451; KEGG: slo:Shew_2928 protein of unknown function DUF1451 YP_001675434.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001675435.1 PFAM: Rare lipoprotein B; KEGG: slo:Shew_2930 rare lipoprotein B YP_001675436.1 KEGG: slo:Shew_2931 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta YP_001675437.1 KEGG: sbm:Shew185_3314 nicotinate (nicotinamide) nucleotide adenylyltransferase; TIGRFAM: cytidyltransferase-related domain; nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase YP_001675438.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: sbm:Shew185_3315 iojap-like protein YP_001675439.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001675440.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: slo:Shew_2935 peptidoglycan glycosyltransferase YP_001675441.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: slo:Shew_2936 rod shape-determining protein RodA YP_001675442.1 TIGRFAM: lytic murein transglycosylase B; KEGG: sbm:Shew185_3319 lytic murein transglycosylase B YP_001675443.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; Sporulation domain protein; KEGG: slo:Shew_2938 rare lipoprotein A YP_001675444.1 PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: slo:Shew_2939 serine-type D-Ala-D-Ala carboxypeptidase YP_001675445.1 PFAM: protein of unknown function DUF493; KEGG: saz:Sama_2593 hypothetical protein YP_001675446.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001675447.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001675448.1 TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_0987 ribosomal-protein-alanine acetyltransferase YP_001675449.1 KEGG: sfr:Sfri_0690 hypothetical protein YP_001675450.1 KEGG: shm:Shewmr7_3071 hypothetical protein YP_001675451.1 KEGG: slo:Shew_2947 hypothetical protein YP_001675452.1 PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: shw:Sputw3181_3141 ATPase AAA-2 domain protein YP_001675453.1 PFAM: protein of unknown function DUF152; KEGG: slo:Shew_2949 protein of unknown function DUF152 YP_001675454.1 KEGG: slo:Shew_2950 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001675455.1 KEGG: shm:Shewmr7_3075 putative lipoprotein YP_001675456.1 KEGG: vvu:VV1_2366 predicted exporter of the RND superfamily YP_001675457.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: spc:Sputcn32_0796 methyl-accepting chemotaxis sensory transducer YP_001675458.1 catalyzes the formation of L-proline from L-ornithine YP_001675459.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: slo:Shew_2956 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001675460.1 KEGG: slo:Shew_2957 hypothetical protein YP_001675461.1 KEGG: sfr:Sfri_0844 hypothetical protein YP_001675462.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: shw:Sputw3181_3383 pseudouridine synthase YP_001675463.1 KEGG: slo:Shew_2974 transferase hexapeptide repeat containing protein YP_001675464.1 PFAM: peptidase M13 neprilysin; peptidase M13; KEGG: shw:Sputw3181_3384 endothelin-converting enzyme 1 YP_001675465.1 KEGG: she:Shewmr4_3180 hypothetical protein YP_001675466.1 KEGG: slo:Shew_2971 hypothetical protein YP_001675467.1 KEGG: slo:Shew_2970 hypothetical protein YP_001675468.1 PFAM: Glutathione S-transferase domain; KEGG: slo:Shew_2968 glutathione S-transferase, N-terminal domain YP_001675469.1 PFAM: membrane-flanked domain; KEGG: sfr:Sfri_0836 membrane-flanked domain YP_001675470.1 KEGG: she:Shewmr4_3186 putative manganese transporter YP_001675471.1 PFAM: beta-lactamase; KEGG: son:SO_0914 hypothetical protein YP_001675472.1 PFAM: protein of unknown function DUF1456; KEGG: slo:Shew_2963 protein of unknown function DUF1456 YP_001675473.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_001675475.1 PFAM: protein of unknown function DUF262; KEGG: pen:PSEEN5223 hypothetical protein YP_001675476.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: shw:Sputw3181_3558 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001675477.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: slo:Shew_0608 molybdopterin oxidoreductase YP_001675478.1 KEGG: slo:Shew_2976 hypothetical protein YP_001675479.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: sbm:Shew185_3636 phosphoesterase PA-phosphatase related YP_001675480.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: slo:Shew_2977 diguanylate cyclase YP_001675481.1 TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: domain of unknown function DUF1730; KEGG: slo:Shew_2979 putative iron-sulfur cluster binding protein YP_001675482.1 PFAM: protein of unknown function DUF1458; KEGG: sfr:Sfri_0829 protein of unknown function DUF1458 YP_001675483.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: mxa:MXAN_5223 4-carboxymuconolactone decarboxylase domain protein YP_001675484.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ppr:PBPRB1577 hypothetical transcriptional regulator YP_001675485.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sbm:Shew185_4223 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_001675486.1 PFAM: DSBA oxidoreductase; KEGG: shw:Sputw3181_3957 DsbA oxidoreductase YP_001675487.1 PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: sbm:Shew185_4225 cytochrome c biogenesis protein transmembrane region YP_001675488.1 KEGG: shw:Sputw3181_3959 hypothetical protein YP_001675489.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbm:Shew185_3641 transcriptional regulator, LysR family YP_001675490.1 PFAM: Metal-dependent hydrolase HDOD; KEGG: slo:Shew_2988 putative signal transduction protein YP_001675491.1 PFAM: lipolytic protein G-D-S-L family; KEGG: saz:Sama_2630 lipolytic enzyme, G-D-S-L YP_001675492.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: cps:CPS_1162 TonB-dependent vitamin B12 receptor YP_001675493.1 PFAM: NADPH-dependent FMN reductase; KEGG: cps:CPS_1243 FMN reductase, NADPH-dependent YP_001675494.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: cps:CPS_1244 transcriptional regulator, LysR family YP_001675495.1 SMART: extracellular solute-binding protein family 3; KEGG: slo:Shew_3001 extracellular solute-binding protein, family 3 YP_001675496.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: ppr:PBPRB1023 hypothetical ribosomal small subunit pseudouridine synthase A YP_001675497.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001675498.1 KEGG: slo:Shew_2639 hypothetical protein YP_001675499.1 KEGG: slo:Shew_3002 hypothetical protein YP_001675500.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: slo:Shew_3008 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001675501.1 PFAM: glucose sorbosone dehydrogenase; KEGG: ppr:PBPRB1412 hypothetical glucose dehydrogenase YP_001675502.1 PFAM: protein of unknown function DUF1704; KEGG: slo:Shew_2900 protein of unknown function DUF1704 YP_001675503.1 The second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001675504.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: vvy:VV2684 GGDEF family protein YP_001675505.1 PFAM: ferredoxin-dependent glutamate synthase; SMART: zinc finger CDGSH-type domain protein; KEGG: cps:CPS_1903 glutamate synthase domain protein YP_001675506.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); KEGG: sbl:Sbal_1573 HAD-superfamily hydrolase, subfamily IB (PSPase-like) YP_001675507.1 KEGG: sfr:Sfri_0910 UTP-GlnB uridylyltransferase, GlnD; TIGRFAM: protein-P-II uridylyltransferase; PFAM: amino acid-binding ACT domain protein; GlnD PII-uridylyltransferase YP_001675508.1 KEGG: sdn:Sden_2069 hypothetical protein YP_001675509.1 KEGG: pin:Ping_2245 hypothetical protein YP_001675510.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: slo:Shew_3327 RNA-metabolising metallo-beta-lactamase YP_001675511.1 KEGG: slo:Shew_2655 hypothetical protein YP_001675512.1 KEGG: ppr:PBPRB0452 hypothetical protein YP_001675513.1 PFAM: band 7 protein; KEGG: slo:Shew_0978 band 7 protein YP_001675514.1 KEGG: slo:Shew_1730 hypothetical protein YP_001675515.1 KEGG: vha:VIBHAR_05537 hypothetical protein YP_001675516.1 PFAM: peptidase M13 neprilysin; peptidase M13; KEGG: sfr:Sfri_1958 endothelin-converting enzyme 1 YP_001675517.1 YghU; B2989; one of eight putative glutathione transferase proteins from E. coli YP_001675518.1 PFAM: protein of unknown function DUF985; KEGG: spc:Sputcn32_3190 protein of unknown function DUF985 YP_001675519.1 KEGG: slo:Shew_3030 hypothetical protein YP_001675520.1 KEGG: vfi:VFA0969 guanine deaminase; TIGRFAM: Guanine deaminase; PFAM: amidohydrolase YP_001675521.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: aha:AHA_0949 xanthine/uracil permease family protein YP_001675522.1 PFAM: SpoOM family protein; KEGG: pha:PSHAa0857 SpoOM-related protein YP_001675523.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: rca:Rcas_3855 mandelate racemase/muconate lactonizing protein YP_001675524.1 PFAM: BCCT transporter; KEGG: vha:VIBHAR_03056 hypothetical protein YP_001675525.1 PFAM: FAD dependent oxidoreductase; KEGG: msm:MSMEG_3987 FAD dependent oxidoreductase YP_001675526.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rru:Rru_A3003 transcriptional regulator, GntR family YP_001675527.1 KEGG: tva:TVAG_168130 smooth muscle caldesmon, putative Pfam: MAP1B_neuraxin PROSITE: FUMARATE_LYASES ARG_RICH GLU_RICH LYS_RICH SER_RICH YP_001675528.1 PFAM: sodium/glutamate symporter; KEGG: slo:Shew_0103 sodium/glutamate symporter YP_001675529.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: vfi:VFA0117 transporter, drug/metabolite exporter family YP_001675530.1 KEGG: son:SO_4025 OmpA-like transmembrane domain protein YP_001675531.1 PFAM: OsmC family protein; protein of unknown function DUF181; KEGG: sbl:Sbal_0643 protein of unknown function DUF181 YP_001675532.1 KEGG: sbl:Sbal_0642 hypothetical protein YP_001675533.1 PFAM: carbohydrate kinase FGGY; KEGG: maq:Maqu_1344 carbohydrate kinase, FGGY YP_001675534.1 PFAM: FAD dependent oxidoreductase; KEGG: maq:Maqu_1345 FAD dependent oxidoreductase YP_001675535.1 PFAM: FAD linked oxidase domain protein; KEGG: pap:PSPA7_2132 hypothetical protein YP_001675536.1 SMART: helix-turn-helix- domain containing protein AraC type; KEGG: pmy:Pmen_1557 helix-turn-helix-domain containing protein, AraC type YP_001675537.1 PFAM: Ankyrin; KEGG: tva:TVAG_291510 ankyrin repeat protein, putative Pfam: Ank Clathrin PROSITE: ANK_REPEAT ANK_REP_REGION YP_001675538.1 KEGG: sbm:Shew185_3668 hypothetical protein YP_001675539.1 PFAM: Na+/H+ antiporter NhaC; KEGG: vco:VC0395_1016 hypothetical protein YP_001675540.1 KEGG: slo:Shew_2580 hypothetical protein YP_001675541.1 KEGG: slo:Shew_1222 hypothetical protein YP_001675542.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: ppr:PBPRB1929 putative Cold shock-like protein YP_001675543.1 KEGG: vfi:VFA1093 hypothetical protein YP_001675544.1 KEGG: son:SO_2929 hypothetical protein YP_001675545.1 PFAM: protein of unknown function UPF0066; KEGG: sfu:Sfum_0270 protein of unknown function UPF0066 YP_001675546.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sdn:Sden_0245 GGDEF domain YP_001675547.1 KEGG: vfi:VF1097 BAX protein YP_001675548.1 KEGG: vvy:VVA0149 hypothetical protein YP_001675549.1 PFAM: secretion protein HlyD family protein; KEGG: vvu:VV2_1308 multidrug resistance efflux pump YP_001675550.1 KEGG: sdn:Sden_0849 hypothetical protein YP_001675551.1 KEGG: cps:CPS_2621 cytochrome c family protein YP_001675552.1 TIGRFAM: peptidase T-like protein; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: vfi:VFA0004 tripeptidase T YP_001675553.1 PFAM: protein of unknown function DUF330; KEGG: cps:CPS_3078 putative lipoprotein YP_001675554.1 PFAM: Mammalian cell entry related domain protein; KEGG: cps:CPS_3077 putative paraquat-inducible protein B YP_001675555.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: Paraquat-inducible protein A; KEGG: cps:CPS_3076 integral membrane protein, PqiA family YP_001675556.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: slo:Shew_3055 CMP/dCMP deaminase, zinc-binding YP_001675557.1 KEGG: sfr:Sfri_2517 cation diffusion facilitator family transporter YP_001675558.1 PFAM: protein of unknown function DUF81; KEGG: cvi:CV_2551 probable transmembrane protein YP_001675559.1 PFAM: 17 kDa surface antigen; KEGG: vpa:VP1192 putative outer membrane lipoprotein Pcp YP_001675561.1 PFAM: cation antiporter; KEGG: sfr:Sfri_2281 cation antiporter YP_001675562.1 PFAM: multiple resistance and pH regulation protein F; KEGG: rru:Rru_A1640 multiple resistance and pH regulation protein F YP_001675563.1 TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; KEGG: rba:RB1436 Na+/H+ antiporter YP_001675564.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001675565.1 PFAM: NADH-ubiquinone oxidoreductase chain 4L; KEGG: pla:Plav_2968 NADH-ubiquinone oxidoreductase chain 4L YP_001675566.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_001675567.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: pla:Plav_2966 NADH dehydrogenase (quinone) YP_001675568.1 KEGG: smd:Smed_3627 hypothetical protein YP_001675569.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; in S. meliloti it is known to be involved specifically with K+ transport YP_001675570.1 KEGG: vpa:VP1418 hypothetical protein YP_001675572.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: aha:AHA_2229 methyl-accepting chemotaxis protein YP_001675573.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_001675574.1 KEGG: dde:Dde_3309 ABC transporter, periplasmic substrate-binding protein, putative YP_001675576.1 PFAM: protein of unknown function DUF1568; KEGG: shm:Shewmr7_1178 protein of unknown function DUF1568 YP_001675577.1 KEGG: slo:Shew_3059 hypothetical protein YP_001675578.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001675579.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001675580.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001675581.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: slo:Shew_3065 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family YP_001675582.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; 2-polyprenyl-6-methoxyphenol 4-hydroxylase; PFAM: monooxygenase FAD-binding; KEGG: slo:Shew_3066 2-polyprenyl-6-methoxyphenol 4-hydroxylase YP_001675583.1 TIGRFAM: yecA family protein; PFAM: protein of unknown function UPF0149; KEGG: shw:Sputw3181_0727 YecA family protein YP_001675584.1 PFAM: protein of unknown function DUF710; KEGG: slo:Shew_3068 protein of unknown function DUF710 YP_001675585.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: sfr:Sfri_3156 glycerophosphoryl diester phosphodiesterase-like protein YP_001675586.1 KEGG: sfr:Sfri_3157 hypothetical protein YP_001675587.1 KEGG: sfr:Sfri_3158 hypothetical protein YP_001675590.1 SMART: regulatory protein Crp; KEGG: rme:Rmet_0213 cyclic nucleotide-binding domain (cNMP-BD) protein YP_001675591.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: slo:Shew_3069 5-formyltetrahydrofolate cyclo-ligase YP_001675592.1 PFAM: protein of unknown function DUF1326; KEGG: cps:CPS_2422 hypothetical protein YP_001675593.1 KEGG: cps:CPS_2421 hypothetical protein YP_001675594.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001675595.1 KEGG: slo:Shew_3074 pilin, putative YP_001675596.1 KEGG: sfr:Sfri_3092 methylation site containing protein YP_001675597.1 KEGG: slo:Shew_3075 hypothetical protein YP_001675598.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shn:Shewana3_3224 lysine exporter protein (LysE/YggA) YP_001675599.1 KEGG: son:SO_3659 thiol:disulfide interchange protein, putative YP_001675600.1 PFAM: AMP-dependent synthetase and ligase; KEGG: shw:Sputw3181_3197 AMP-dependent synthetase and ligase YP_001675601.1 KEGG: slo:Shew_3087 lipid A ABC exporter family, fused ATPase and inner membrane subunits; TIGRFAM: lipid A ABC exporter family, fused ATPase and inner membrane subunits; PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001675602.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: shn:Shewana3_3233 pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001675603.1 PFAM: protein of unknown function DUF1008; KEGG: son:SO_3668 hypothetical protein YP_001675604.1 TIGRFAM: TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: shw:Sputw3181_3201 TonB-dependent heme/hemoglobin receptor family protein YP_001675605.1 TIGRFAM: TonB family protein; KEGG: sbm:Shew185_1020 TonB family protein YP_001675606.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: sbm:Shew185_1019 MotA/TolQ/ExbB proton channel YP_001675607.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: sdn:Sden_0787 biopolymer transport protein ExbD/TolR YP_001675608.1 PFAM: periplasmic binding protein; KEGG: sbl:Sbal_0948 periplasmic binding protein YP_001675609.1 PFAM: transport system permease protein; KEGG: shn:Shewana3_3240 transport system permease protein YP_001675610.1 with HmuTU is involved in the transport of hemin YP_001675611.1 PFAM: regulatory protein TetR; KEGG: vfi:VF1676 hypothetical protein YP_001675612.1 PFAM: bifunctional deaminase-reductase domain protein; KEGG: vvu:VV2_1034 dihydrofolate reductase YP_001675613.1 PFAM: protein of unknown function DUF218; KEGG: xac:XAC0380 hypothetical protein YP_001675614.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pha:PSHAb0015 putative transcriptional regulatory protein (LysR family) YP_001675615.1 PFAM: transmembrane pair domain protein; KEGG: vfi:VFA1143 hypothetical membrane spanning protein YP_001675616.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001675617.1 KEGG: slo:Shew_3089 hypothetical protein YP_001675618.1 PFAM: periplasmic nitrate reductase NapE; KEGG: psa:PST_1270 periplasmic nitrate reductase NapE subunit YP_001675619.1 TIGRFAM: trimethylamine-N-oxide reductase c-type cytochrome TorC; PFAM: NapC/NirT cytochrome c domain protein; KEGG: slo:Shew_2797 trimethylamine-N-oxide reductase C-type cytochrome TorC YP_001675620.1 TIGRFAM: trimethylamine-N-oxide reductase TorA; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfr:Sfri_1994 trimethylamine-N-oxide reductase TorA YP_001675621.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor YP_001675622.1 TIGRFAM: TMAO reductase sytem sensor TorS; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: sfr:Sfri_1992 multi-sensor hybrid histidine kinase YP_001675623.1 periplasmic sensory protein associated with the TorRS two-component regulatory system YP_001675624.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes YP_001675625.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_0030 hypothetical protein YP_001675626.1 PFAM: Ion transport protein; KEGG: pha:PSHAb0529 putative cation transporter component YP_001675627.1 KEGG: slo:Shew_3090 hypothetical protein YP_001675628.1 PFAM: membrane-flanked domain; KEGG: slo:Shew_3091 membrane-flanked domain protein YP_001675629.1 PFAM: membrane-flanked domain; KEGG: slo:Shew_3092 membrane-flanked domain protein YP_001675630.1 PFAM: protein of unknown function DUF924; KEGG: shm:Shewmr7_3145 protein of unknown function DUF924 YP_001675631.1 PFAM: UspA domain protein; KEGG: slo:Shew_3100 UspA domain protein YP_001675632.1 PFAM: UspA domain protein; KEGG: slo:Shew_3101 UspA domain protein YP_001675633.1 KEGG: slo:Shew_3102 hypothetical protein YP_001675634.1 PFAM: aldehyde dehydrogenase; KEGG: sbm:Shew185_1007 aldehyde dehydrogenase YP_001675635.1 PFAM: regulatory protein TetR; KEGG: slo:Shew_3104 transcriptional regulator, TetR family YP_001675636.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; KEGG: slo:Shew_0727 integral membrane sensor signal transduction histidine kinase YP_001675637.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: slo:Shew_0726 two component, sigma54 specific, transcriptional regulator, fis family YP_001675638.1 PFAM: protein of unknown function DUF214; KEGG: shm:Shewmr7_3157 protein of unknown function DUF214 YP_001675639.1 PFAM: protein of unknown function DUF214; KEGG: shm:Shewmr7_3158 protein of unknown function DUF214 YP_001675640.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO_3692 ABC transporter, ATP-binding protein YP_001675642.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: slo:Shew_0721 efflux transporter, RND family, MFP subunit YP_001675643.1 PFAM: porin Gram-negative type; KEGG: slo:Shew_2283 porin, gram-negative type YP_001675644.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: esa:ESA_01519 hypothetical protein YP_001675645.1 KEGG: eca:ECA2031 respiratory nitrate reductase 1 alpha chain; TIGRFAM: nitrate reductase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_001675646.1 TIGRFAM: nitrate reductase, beta subunit; KEGG: kpn:KPN_02213 nitrate reductase 1, Fe-S (beta) subunit YP_001675647.1 TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: Nitrate reductase delta subunit; KEGG: eca:ECA2033 respiratory nitrate reductase 1 delta chain YP_001675648.1 KEGG: esa:ESA_01523 hypothetical protein; TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase gamma subunit YP_001675649.1 KEGG: spc:Sputcn32_2918 transposase, IS4 family protein YP_001675650.1 KEGG: shn:Shewana3_1487 porin, gram-negative type YP_001675651.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: slo:Shew_2282 transcriptional regulator, fis family YP_001675652.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: slo:Shew_2281 flavocytochrome c YP_001675653.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: slo:Shew_2280 phenylalanine/histidine ammonia-lyase YP_001675654.1 KEGG: slo:Shew_2279 tetraheme cytochrome c YP_001675655.1 KEGG: saz:Sama_2866 hypothetical protein YP_001675656.1 KEGG: ppr:PBPRB0735 hypothetical protein YP_001675657.1 PFAM: periplasmic binding protein; KEGG: shn:Shewana3_3272 periplasmic binding protein YP_001675658.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001675659.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_001675660.1 PFAM: cobalbumin biosynthesis protein; KEGG: slo:Shew_0716 cobalbumin biosynthesis enzyme YP_001675661.1 TIGRFAM: cobalamin 5'-phosphate synthase; PFAM: cobalamin-5-phosphate synthase CobS; KEGG: sbm:Shew185_0978 cobalamin 5'-phosphate synthase YP_001675663.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001675664.1 PFAM: transport system permease protein; KEGG: sbl:Sbal_3365 transport system permease protein YP_001675665.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_0712 ABC transporter-related protein YP_001675666.1 PFAM: Phosphoglycerate mutase; KEGG: slo:Shew_0711 phosphoglycerate mutase YP_001675667.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_001675668.1 PFAM: Urease accessory protein UreD; KEGG: vfi:VF0676 urease accessory protein UreD YP_001675669.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter YP_001675670.1 KEGG: ppf:Pput_2845 urease, beta subunit; TIGRFAM: urease, beta subunit; PFAM: Urease beta subunit YP_001675671.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_001675672.1 PFAM: UreE urease accessory domain protein; KEGG: vfi:VF0672 urease accessory protein UreE YP_001675673.1 PFAM: Urease accessory protein UreF; KEGG: vfi:VF0671 urease accessory protein UreF YP_001675674.1 TIGRFAM: urease accessory protein UreG; PFAM: cobalamin synthesis protein P47K; KEGG: vfi:VF0670 urease accessory protein UreG YP_001675675.1 PFAM: Endoribonuclease L-PSP; KEGG: ppr:PBPRB1772 hypothetical endoribonuclease L-PSP YP_001675678.1 catalyzes the reaction of formaldehyde with glutathione to form S-hydroxymethylglutathione YP_001675679.1 PFAM: MscS Mechanosensitive ion channel; KEGG: vvu:VV1_0007 small-conductance mechanosensitive channel YP_001675680.1 KEGG: sdn:Sden_0577 hypothetical protein YP_001675681.1 catalyzes the formation of inosine from adenosine YP_001675682.1 PFAM: TM2 domain containing protein?; KEGG: ppd:Ppro_2995 TM2 domain containing protein+B7201 YP_001675683.1 KEGG: vvy:VVA1337 TagA-related protein YP_001675684.1 PFAM: RDD domain containing protein; KEGG: shm:Shewmr7_2450 RDD domain containing protein YP_001675685.1 KEGG: vha:VIBHAR_05537 hypothetical protein YP_001675687.1 PFAM: peptidase M4 thermolysin; Propeptide peptidase M4 and M36; Peptidase M4 thermolysin; KEGG: mxa:MXAN_5442 peptidase, M4 (thermolysin) family YP_001675688.1 PFAM: extracellular solute-binding protein family 3; KEGG: son:SO_1044 amino acid ABC transporter, periplasmic amino acid-binding protein YP_001675689.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_3165 polar amino acid ABC transporter, inner membrane subunit YP_001675690.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_3164 ABC transporter-related protein YP_001675691.1 PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: slo:Shew_0707 YbaK/prolyl-tRNA synthetase associated region YP_001675692.1 KEGG: shw:Sputw3181_2912 hypothetical protein YP_001675693.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: son:SO_4295 NAD(P)H dehydrogenase (quinone) YP_001675694.1 PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: shw:Sputw3181_0452 Na+ dependent nucleoside transporter domain protein YP_001675695.1 KEGG: ppr:PBPRB0398 hypothetical protein YP_001675696.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: slo:Shew_0490 peptidase S9, prolyl oligopeptidase active site domain protein YP_001675698.1 KEGG: vvu:VV1_0767 hypothetical protein YP_001675699.1 KEGG: cdf:CD3145 putative serine-aspartate-rich surface anchored fibrinogen-binding protein YP_001675701.1 KEGG: sbm:Shew185_3407 hypothetical protein YP_001675702.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: slo:Shew_2195 NADH dehydrogenase YP_001675703.1 KEGG: vha:VIBHAR_04801 hypothetical protein YP_001675704.1 KEGG: sbm:Shew185_1422 lipoprotein, putative YP_001675705.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: mmw:Mmwyl1_4378 helix-turn-helix-domain containing protein AraC type YP_001675706.1 PFAM: major facilitator superfamily MFS_1; KEGG: pin:Ping_1574 transporter major facilitator superfamily MFS_1 YP_001675707.1 KEGG: ppr:PBPRB1341 hypothetical protein YP_001675708.1 PFAM: secretion protein HlyD family protein; KEGG: ppr:PBPRB1340 putative secretion protein YP_001675709.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ppr:PBPRB1339 hypothetical transcriptional regulator YP_001675710.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: shw:Sputw3181_2351 TonB-dependent receptor YP_001675711.1 PFAM: Na+/H+ antiporter NhaC; KEGG: slo:Shew_0698 Na+/H+ antiporter NhaC YP_001675712.1 KEGG: sbl:Sbal_3290 hypothetical protein YP_001675713.1 PFAM: permease; KEGG: vha:VIBHAR_05267 hypothetical protein YP_001675714.1 PFAM: protein of unknown function DUF331; KEGG: slo:Shew_0695 protein of unknown function DUF331 YP_001675715.1 KEGG: vco:VC0395_0913 putative lipoprotein YP_001675716.1 PFAM: 3'-5' exonuclease; KEGG: shn:Shewana3_0980 3'-5' exonuclease YP_001675718.1 KEGG: shw:Sputw3181_2350 hypothetical protein YP_001675719.1 KEGG: sfr:Sfri_3634 hypothetical protein YP_001675720.1 KEGG: sfr:Sfri_3633 cytochrome c, putative YP_001675721.1 PFAM: transcriptional regulator domain protein; KEGG: sfr:Sfri_3632 response regulator receiver protein YP_001675722.1 KEGG: sfr:Sfri_3631 hypothetical protein YP_001675723.1 KEGG: slo:Shew_0689 hypothetical protein YP_001675724.1 PFAM: DSBA oxidoreductase; KEGG: sbm:Shew185_0941 DsbA oxidoreductase YP_001675725.1 PFAM: glycosyl transferase group 1; KEGG: ana:all2291 glycosyltransferase YP_001675726.1 KEGG: slo:Shew_0679 hypothetical protein YP_001675727.1 KEGG: shn:Shewana3_0871 protoporphyrinogen oxidase YP_001675728.1 PFAM: protein of unknown function DUF1111; KEGG: sdn:Sden_0723 protein of unknown function DUF1111 YP_001675729.1 KEGG: slo:Shew_0676 putative lipoprotein YP_001675730.1 KEGG: sdn:Sden_0721 hypothetical protein YP_001675731.1 KEGG: slo:Shew_0673 hypothetical protein YP_001675732.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_001675733.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: shn:Shewana3_0865 TrkA-C domain protein YP_001675734.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_001675735.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001675736.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: son:SO_3728 uroporphyrin-III C-methyltransferase YP_001675737.1 PFAM: phospholipase A1; KEGG: saz:Sama_2893 phospholipase A(1) YP_001675738.1 KEGG: sbm:Shew185_0925 hypothetical protein YP_001675739.1 PFAM: protein of unknown function RIO1; KEGG: sbm:Shew185_0676 protein of unknown function RIO1 YP_001675740.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: slo:Shew_0669 redoxin domain protein YP_001675741.1 KEGG: pfl:PFL_5750 hypothetical protein YP_001675742.1 KEGG: sbl:Sbal_3412 hypothetical protein YP_001675743.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_001675744.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_001675745.1 TIGRFAM: sulfite reductase [NADPH] flavoprotein, alpha chain; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; flavodoxin/nitric oxide synthase; KEGG: slo:Shew_0665 sulfite reductase (NADPH) flavoprotein, alpha chain YP_001675746.1 PFAM: alanine dehydrogenase/PNT domain protein; KEGG: slo:Shew_0664 alanine dehydrogenase/PNT domain protein YP_001675747.1 KEGG: slo:Shew_0663 oxidoreductase YP_001675748.1 PFAM: NAD(P) transhydrogenase beta subunit; KEGG: slo:Shew_0662 NAD(P) transhydrogenase, beta subunit YP_001675749.1 PFAM: MltA-interacting MipA family protein; KEGG: vfi:VF1562 hypothetical protein YP_001675750.1 PFAM: regulatory protein TetR; KEGG: saz:Sama_0733 putative transcriptional regulator, TetR family YP_001675751.1 KEGG: shn:Shewana3_0850 hypothetical protein YP_001675752.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_001675753.1 TIGRFAM: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; PFAM: lipid A biosynthesis acyltransferase; KEGG: slo:Shew_0658 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase YP_001675754.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: nar:Saro_3961 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001675755.1 KEGG: pat:Patl_1751 hypothetical protein YP_001675756.1 KEGG: slo:Shew_0657 putative nitric oxide reductase (subunit B) transmembrane protein YP_001675757.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_001675758.1 PFAM: peptidase M16 domain protein; KEGG: shn:Shewana3_0841 peptidase M16 domain protein YP_001675759.1 PFAM: StbA family protein; KEGG: cko:CKO_02852 hypothetical protein YP_001675760.1 KEGG: cko:CKO_02851 hypothetical protein YP_001675761.1 catalyzes the formation of pyruvate from serine YP_001675762.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_001675763.1 regulates the synthesis and expression of the dsdXA operon and dadA gene YP_001675764.1 KEGG: sfr:Sfri_2004 hypothetical protein YP_001675765.1 KEGG: mmz:MmarC7_1679 tetratricopeptide TPR_2 repeat protein YP_001675767.1 KEGG: bbt:BBta_4307 putative membrane protein of unknown function YP_001675768.1 KEGG: vha:VIBHAR_01968 hypothetical protein YP_001675769.1 KEGG: eca:ECA0649 putative DNA mismatch repair protein YP_001675770.1 KEGG: vvy:VV2395 hypothetical protein YP_001675772.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001675773.1 KEGG: slo:Shew_0627 hypothetical protein YP_001675774.1 PFAM: protein of unknown function DUF350; KEGG: slo:Shew_0626 protein of unknown function DUF350 YP_001675775.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001675776.1 KEGG: slo:Shew_0624 hypothetical protein YP_001675777.1 PFAM: PspA/IM30 family protein; KEGG: sfr:Sfri_3266 phage shock protein A, PspA YP_001675778.1 KEGG: shw:Sputw3181_0852 hypothetical protein YP_001675779.1 KEGG: slo:Shew_0621 hypothetical protein YP_001675780.1 PFAM: Ion transport protein; Ion transport 2 domain protein; KEGG: sbm:Shew185_0885 ion transport 2 domain protein YP_001675781.1 PFAM: adenylate cyclase; KEGG: slo:Shew_0619 adenylate cyclase YP_001675782.1 PFAM: protein of unknown function DUF47; KEGG: slo:Shew_0618 protein of unknown function DUF47 YP_001675783.1 PFAM: phosphate transporter; KEGG: slo:Shew_0617 phosphate transporter YP_001675784.1 KEGG: slo:Shew_0616 SH3 domain protein domain protein YP_001675785.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain YP_001675786.1 PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: ppr:PBPRA3375 putative methyl-accepting chemotaxis protein YP_001675787.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: ppr:PBPRA3375 putative methyl-accepting chemotaxis protein YP_001675788.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001675789.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001675790.1 KEGG: slo:Shew_0605 hypothetical protein YP_001675791.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: shw:Sputw3181_0836 DEAD/DEAH box helicase domain protein YP_001675792.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_001675793.1 KEGG: dvl:Dvul_0140 lipoprotein, putative YP_001675794.1 PFAM: conserved hypothetical protein; KEGG: sbm:Shew185_0864 hypothetical protein YP_001675795.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbl:Sbal_3476 ABC transporter related YP_001675796.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_0592 hypothetical protein YP_001675797.1 PFAM: glucose-methanol-choline oxidoreductase; KEGG: sbm:Shew185_0857 glucose-methanol-choline oxidoreductase YP_001675798.1 KEGG: slo:Shew_0590 hypothetical protein YP_001675799.1 KEGG: sbm:Shew185_0855 alpha/beta hydrolase fold YP_001675800.1 PFAM: protein of unknown function UPF0270; KEGG: saz:Sama_3001 protein of unknown function UPF0270 YP_001675801.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: slo:Shew_0587 phosphoribulokinase YP_001675802.1 KEGG: sbl:Sbal_0579 Sel1 domain protein repeat-containing protein YP_001675803.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_001675804.1 KEGG: shn:Shewana3_0616 hypothetical protein YP_001675805.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: slo:Shew_0583 two component transcriptional regulator, winged helix family YP_001675806.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: slo:Shew_0582 integral membrane sensor signal transduction histidine kinase YP_001675807.1 KEGG: slo:Shew_0581 hypothetical protein YP_001675808.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_001675809.1 PFAM: arginine N-succinyltransferase beta subunit; KEGG: slo:Shew_0579 arginine N-succinyltransferase YP_001675810.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_001675811.1 PFAM: Metal-dependent hydrolase HDOD; KEGG: shn:Shewana3_0608 putative signal transduction protein YP_001675812.1 PFAM: peptidase S15; peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9B dipeptidylpeptidase IV domain protein; KEGG: slo:Shew_0576 peptidase S9, prolyl oligopeptidase active site domain protein YP_001675813.1 TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: she:Shewmr4_0607 glutamine amidotransferase of anthranilate synthase YP_001675814.1 KEGG: dps:DP2970 hypothetical protein YP_001675815.1 TIGRFAM: TonB family protein; KEGG: dps:DP2971 similar to TonB protein YP_001675816.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: dps:DP2972 biopolymer transport protein (ExbD2) YP_001675817.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: dps:DP2973 similar to biopolymer transport protein (ExbB) YP_001675818.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: dps:DP2974 similar to transport protein TolQ YP_001675819.1 KEGG: dps:DP2975 hypothetical protein YP_001675820.1 KEGG: dps:DP2976 hypothetical protein YP_001675821.1 KEGG: dps:DP2977 hypothetical protein YP_001675822.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: dps:DP2978 related to iron (III) ABC transporter, ATP-binding protein YP_001675823.1 PFAM: transport system permease protein; KEGG: dps:DP2979 probable iron (III) ABC transporter, permease protein YP_001675824.1 PFAM: periplasmic binding protein; KEGG: dps:DP2980 probable iron (III) ABC transporter, periplasmic-binding protein YP_001675825.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: dps:DP2981 related to TonB dependent outer membrane receptor YP_001675826.1 PFAM: Stringent starvation protein B; KEGG: slo:Shew_0574 stringent starvation protein B YP_001675827.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_001675828.1 PFAM: cytochrome c1; KEGG: sdn:Sden_3199 cytochrome c1 YP_001675829.1 PFAM: Cytochrome b/b6 domain; KEGG: slo:Shew_0571 cytochrome b/b6, N-terminal domain YP_001675830.1 KEGG: slo:Shew_0570 ubiquinol-cytochrome c reductase, iron-sulfur subunit; TIGRFAM: ubiquinol-cytochrome c reductase, iron-sulfur subunit; PFAM: Rieske [2Fe-2S] domain protein YP_001675831.1 TIGRFAM: HflC protein; PFAM: band 7 protein; KEGG: shn:Shewana3_0600 HflC protein YP_001675832.1 TIGRFAM: HflK protein; PFAM: band 7 protein; KEGG: sbm:Shew185_3765 HflK protein YP_001675833.1 TIGRFAM: GTP1/OBG protein; PFAM: GTP-binding protein HSR1-related; KEGG: slo:Shew_0567 GTP-binding protein, HSR1-related YP_001675834.1 TIGRFAM: RNA chaperone Hfq; PFAM: Like-Sm ribonucleoprotein core; KEGG: slo:Shew_0566 RNA chaperone Hfq YP_001675835.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001675836.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001675837.1 PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: slo:Shew_0563 N-acetylmuramoyl-L-alanine amidase YP_001675838.1 PFAM: protein of unknown function UPF0079; KEGG: shn:Shewana3_0593 protein of unknown function UPF0079 YP_001675839.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family domain protein; KEGG: spc:Sputcn32_3285 carbohydrate kinase, YjeF related protein YP_001675840.1 KEGG: saz:Sama_3031 hypothetical protein YP_001675841.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001675842.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001675843.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_001675844.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sbl:Sbal_0548 protein of unknown function DUF6, transmembrane YP_001675845.1 PFAM: MscS Mechanosensitive ion channel; KEGG: slo:Shew_0555 MscS mechanosensitive ion channel YP_001675846.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: she:Shewmr4_0586 glycerophosphoryl diester phosphodiesterase YP_001675847.1 KEGG: shw:Sputw3181_0648 hypothetical protein YP_001675848.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: slo:Shew_0553 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001675849.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: shn:Shewana3_0581 BFD domain protein (2Fe-2S)-binding domain protein YP_001675850.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001675851.1 KEGG: slo:Shew_0550 L-sorbosone dehydrogenase, putative YP_001675852.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001675853.1 PFAM: protein of unknown function UPF0227; KEGG: slo:Shew_0548 protein of unknown function UPF0227 YP_001675854.1 PFAM: metallophosphoesterase; Calcineurin phosphoesterase domain protein; KEGG: shm:Shewmr7_0756 calcineurin phosphoesterase C-terminal domain protein YP_001675855.1 PFAM: protein of unknown function DUF1249; KEGG: shw:Sputw3181_3405 protein of unknown function DUF1249 YP_001675856.1 PFAM: NUDIX hydrolase; KEGG: slo:Shew_0545 ADP-ribose diphosphatase YP_001675857.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_001675858.1 KEGG: sbm:Shew185_0780 hypothetical protein YP_001675859.1 KEGG: slo:Shew_0542 hypothetical protein YP_001675860.1 PFAM: protein of unknown function DUF461; KEGG: spc:Sputcn32_0765 protein of unknown function DUF461 YP_001675861.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: shn:Shewana3_0721 enoyl-CoA hydratase/isomerase YP_001675862.1 PFAM: PspC domain protein; KEGG: slo:Shew_0538 phage shock protein C, PspC YP_001675863.1 KEGG: shn:Shewana3_0719 hypothetical protein YP_001675864.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase DuS; KEGG: slo:Shew_0536 TIM-barrel protein, YjbN family YP_001675865.1 PFAM: regulatory protein LysR; KEGG: son:SO_4571 transcriptional regulator, LysR family YP_001675866.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_3153 transcriptional regulator, LysR family YP_001675867.1 KEGG: son:SO_1779 decaheme cytochrome c YP_001675868.1 KEGG: slo:Shew_3276 hypothetical protein YP_001675869.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001675870.1 KEGG: slo:Shew_3278 replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; SMART: AAA ATPase YP_001675871.1 KEGG: slo:Shew_3279 hypothetical protein YP_001675872.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001675873.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001675874.1 binds single-stranded DNA at the primosome assembly site YP_001675875.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001675876.1 PFAM: protein of unknown function DUF481; KEGG: shw:Sputw3181_3423 protein of unknown function DUF481 YP_001675877.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_001675878.1 KEGG: slo:Shew_3289 ribonuclease R; TIGRFAM: VacB and RNase II family 3'-5' exoribonuclease; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; Ribonuclease B OB region domain; Ribonuclease R winged-helix domain protein; SMART: Cold shock protein YP_001675879.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: slo:Shew_3290 Sel1 domain protein repeat-containing protein YP_001675880.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001675881.1 KEGG: slo:Shew_3292 hypothetical protein YP_001675882.1 forms a direct contact with the tRNA during translation YP_001675883.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001675884.1 PFAM: AFG1-family ATPase; KEGG: slo:Shew_3295 AFG1-family ATPase YP_001675885.1 PFAM: protein of unknown function DUF1043 YP_001675886.1 KEGG: slo:Shew_3296 protease Do; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001675887.1 TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: son:SO_3943 protease DegS YP_001675888.1 KEGG: ppd:Ppro_3498 hypothetical protein YP_001675889.1 PFAM: response regulator receiver; KEGG: vha:VIBHAR_05158 hypothetical protein YP_001675890.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: vha:VIBHAR_05159 hypothetical protein YP_001675891.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001675892.1 PFAM: BolA family protein; KEGG: slo:Shew_3299 BolA family protein YP_001675893.1 KEGG: shm:Shewmr7_3339 SpoIIAA family protein YP_001675894.1 PFAM: toluene tolerance family protein; KEGG: sbl:Sbal_3659 toluene tolerance family protein YP_001675895.1 PFAM: Mammalian cell entry related domain protein; KEGG: shw:Sputw3181_3450 mammalian cell entry related domain protein YP_001675896.1 PFAM: protein of unknown function DUF140; KEGG: slo:Shew_3303 protein of unknown function DUF140 YP_001675897.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_3304 ABC transporter-related protein YP_001675898.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: slo:Shew_3305 Na+/Ca+ antiporter, CaCA family YP_001675899.1 KEGG: slo:Shew_3306 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_001675900.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_001675901.1 PFAM: protein of unknown function DUF1239; KEGG: sbm:Shew185_0689 protein of unknown function DUF1239 YP_001675902.1 TIGRFAM: Cell envelope biogenesis YhbN; PFAM: OstA family protein; KEGG: slo:Shew_3309 OstA family protein YP_001675903.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_3310 ABC transporter-related protein YP_001675904.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001675905.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: slo:Shew_3312 sigma 54 modulation protein/ribosomal protein S30EA YP_001675906.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: slo:Shew_3313 PTS IIA-like nitrogen-regulatory protein PtsN YP_001675907.1 PFAM: conserved hypothetical protein; KEGG: she:Shewmr4_0670 uncharacterized P-loop ATPase protein UPF0042 YP_001675908.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: shw:Sputw3181_3462 phosphotransferase system, phosphocarrier protein HPr YP_001675909.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: slo:Shew_3316 magnesium transporter YP_001675910.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; KEGG: slo:Shew_2687 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_001675911.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen; KEGG: slo:Shew_0908 OmpA/MotB domain protein YP_001675912.1 KEGG: spc:Sputcn32_0707 transposase IS3/IS911 family protein YP_001675913.1 KEGG: slo:Shew_1854 hypothetical protein YP_001675914.1 KEGG: cps:CPS_0069 putative FG-GAP repeat lipoprotein YP_001675915.1 PFAM: Protein of unknown function DUF676 hydrolase domain protein; PGAP1 family protein; KEGG: slo:Shew_3323 lipase-like YP_001675916.1 KEGG: sdn:Sden_3286 hypothetical protein YP_001675917.1 PFAM: major facilitator superfamily MFS_1; KEGG: pha:PSHAa1259 transport protein of the major facilitator YP_001675918.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_001675919.1 PFAM: TOBE domain protein; KEGG: slo:Shew_3338 TOBE domain protein YP_001675920.1 KEGG: sde:Sde_3292 hypothetical protein YP_001675921.1 KEGG: spc:Sputcn32_0688 hypothetical protein YP_001675922.1 PFAM: protein of unknown function DUF134; KEGG: shw:Sputw3181_3483 protein of unknown function DUF134 YP_001675923.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: vfi:VF0677 putative dipeptide ABC transporter YP_001675924.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: vfi:VF0678 oligopeptide transport ATP-binding protein OppD YP_001675925.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vfi:VF0679 oligopeptide transport system permease protein OppC YP_001675926.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: asa:ASA_1795 ABC-type dipeptide/oligopeptide/nickel transporter, permease component YP_001675927.1 PFAM: extracellular solute-binding protein family 5; KEGG: vfi:VF0681 oligopeptide-binding protein OppA YP_001675928.1 PFAM: CopG domain protein DNA-binding domain protein; NikR nickel binding; KEGG: ccv:CCV52592_1897 NikR C nickel binding domain family YP_001675929.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: sbm:Shew185_3172 transcriptional regulator, AraC family YP_001675930.1 KEGG: vha:VIBHAR_04860 hypothetical protein YP_001675931.1 KEGG: ppr:PBPRB1967 hypothetical protein YP_001675932.1 PFAM: protein of unknown function DUF1275; KEGG: mmw:Mmwyl1_2095 protein of unknown function DUF1275 YP_001675933.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: ppr:PBPRA1266 putative peptidyl-prolyl cis-trans isomerase B YP_001675934.1 PFAM: aminotransferase class V; KEGG: vpa:VPA1513 ScrA (aminotransferase) YP_001675935.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: ppr:PBPRB0229 hypothetical ScrC (sensory box/GGDEF familyprotein) (involved in swarmer cell regulation) YP_001675936.1 SMART: extracellular solute-binding protein family 3; KEGG: ppr:PBPRB0228 putative ScrB YP_001675937.1 PFAM: Protein of unknown function DUF1971; KEGG: vfi:VF1779 tellurite resistance protein TehB YP_001675938.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase YP_001675939.1 detoxifies nitric oxide using NADH YP_001675940.1 KEGG: rba:RB6211 hypothetical protein YP_001675941.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: cps:CPS_4655 transcriptional regulator, AraC family YP_001675942.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_001675943.1 PFAM: aminotransferase class I and II; KEGG: pcr:Pcryo_0738 aminotransferase, class I and II YP_001675944.1 PFAM: glycoside hydrolase family 18; Carbohydrate-binding family V/XII; KEGG: son:SO_4085 chitinase A YP_001675945.1 KEGG: vvy:VVA1355 hypothetical protein YP_001675946.1 KEGG: vvy:VVA1354 multidrug resistance efflux pump YP_001675947.1 KEGG: shm:Shewmr7_0124 hypothetical protein YP_001675948.1 KEGG: sfr:Sfri_3640 hypothetical protein YP_001675949.1 PFAM: Xanthine/uracil/vitamin C permease; KEGG: bha:BH0608 hypothetical protein YP_001675950.1 PFAM: CBS domain containing protein; transporter-associated region; Integral membrane protein TerC; KEGG: aha:AHA_2651 inner membrane protein YoaE YP_001675951.1 KEGG: slo:Shew_3216 hypothetical protein YP_001675952.1 KEGG: slo:Shew_0483 hypothetical protein YP_001675953.1 KEGG: slo:Shew_0482 hypothetical protein YP_001675954.1 PFAM: histidine kinase HAMP region domain protein; SMART: extracellular solute-binding protein family 3; metal-dependent phosphohydrolase HD region; KEGG: slo:Shew_3366 metal dependent phosphohydrolase YP_001675955.1 PFAM: protein of unknown function DUF1255; KEGG: pcr:Pcryo_0835 protein of unknown function DUF1255 YP_001675956.1 KEGG: pha:PSHAa2221 hypothetical protein YP_001675957.1 KEGG: slo:Shew_0481 hypothetical protein YP_001675958.1 PFAM: pentapeptide repeat protein; KEGG: ppr:PBPRB0957 hypothetical protein YP_001675959.1 PFAM: amino acid-binding ACT domain protein; KEGG: slo:Shew_2884 glycine cleavage system regulatory protein-like protein YP_001675960.1 PFAM: BCCT transporter; KEGG: vha:VIBHAR_06536 hypothetical protein YP_001675961.1 PFAM: Amidohydrolase 3; KEGG: ppr:PBPRB0017 hypothetical deacylase YP_001675962.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: dde:Dde_3036 CBS YP_001675964.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: aha:AHA_0559 2',3'-cyclic-nucleotide 2'-phosphodiesterase YP_001675965.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: syf:Synpcc7942_1811 diguanylate cyclase (GGDEF domain) with PAS/PAC sensor YP_001675966.1 PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: vfi:VF1108 chaperone protein DnaJ YP_001675967.1 KEGG: mxa:MXAN_4378 hypothetical protein YP_001675968.1 PFAM: protein of unknown function DUF1568; KEGG: sdn:Sden_0135 protein of unknown function DUF1568 YP_001675969.1 PFAM: integrase family protein; KEGG: ecv:APECO1_1715 integrase YP_001675970.1 KEGG: vco:VC0395_1060 hypothetical protein YP_001675971.1 KEGG: vco:VC0395_1061 hypothetical protein YP_001675972.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: ppd:Ppro_1125 resolvase, N-terminal domain YP_001675974.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: gtn:GTNG_2076 hypothetical protein YP_001675975.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001675976.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001675977.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: slo:Shew_0470 MATE efflux family protein YP_001675978.1 PFAM: pentapeptide repeat protein; KEGG: slo:Shew_0469 pentapeptide repeat protein YP_001675979.1 KEGG: slo:Shew_0465 hypothetical protein YP_001675980.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_0468 transcriptional regulator, LysR family YP_001675981.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_0467 efflux transporter, RND family, MFP subunit YP_001675982.1 PFAM: acriflavin resistance protein; KEGG: slo:Shew_0466 acriflavin resistance protein YP_001675983.1 KEGG: slo:Shew_0464 hypothetical protein YP_001675984.1 KEGG: slo:Shew_0463 hypothetical protein YP_001675985.1 KEGG: slo:Shew_0462 hypothetical protein YP_001675986.1 KEGG: slo:Shew_3539 hypothetical protein YP_001675987.1 KEGG: slo:Shew_0460 hypothetical protein YP_001675988.1 KEGG: slo:Shew_0459 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001675989.1 PFAM: PhoH family protein; SMART: AAA ATPase; Nucleotide binding protein PINc; KEGG: slo:Shew_0458 PhoH family protein YP_001675990.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_001675991.1 KEGG: slo:Shew_0456 hypothetical protein YP_001675992.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_0455 uncharacterized protein UPF0114 YP_001675993.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001675994.1 PFAM: response regulator receiver; KEGG: slo:Shew_0453 response regulator receiver protein YP_001675995.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: slo:Shew_0452 diguanylate cyclase YP_001675996.1 PFAM: protein of unknown function DUF1260; KEGG: sfr:Sfri_3513 protein of unknown function DUF1260 YP_001675997.1 KEGG: slo:Shew_0450 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase YP_001675998.1 PFAM: ABC-3 protein; KEGG: sbm:Shew185_3797 ABC-3 protein YP_001675999.1 PFAM: periplasmic solute binding protein; KEGG: shm:Shewmr7_3463 periplasmic solute binding protein YP_001676000.1 KEGG: slo:Shew_0447 hypothetical protein YP_001676001.1 KEGG: shn:Shewana3_0564 hypothetical protein YP_001676003.1 KEGG: slo:Shew_0445 hypothetical protein YP_001676004.1 PFAM: MscS Mechanosensitive ion channel; KEGG: slo:Shew_0444 MscS mechanosensitive ion channel YP_001676005.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_001676006.1 PFAM: MaoC domain protein dehydratase; KEGG: shn:Shewana3_0558 MaoC domain protein dehydratase YP_001676007.1 PFAM: GumN family protein; KEGG: slo:Shew_0438 GumN family protein YP_001676008.1 KEGG: slo:Shew_0437 hypothetical protein YP_001676009.1 KEGG: sbm:Shew185_3811 hypothetical protein YP_001676010.1 KEGG: slo:Shew_0434 hypothetical protein YP_001676011.1 KEGG: slo:Shew_0433 hypothetical protein YP_001676012.1 KEGG: sbm:Shew185_3814 hypothetical protein YP_001676013.1 KEGG: slo:Shew_0431 hypothetical protein YP_001676014.1 KEGG: shm:Shewmr7_3481 response regulator receiver protein YP_001676015.1 PFAM: histone family protein DNA-binding protein; KEGG: slo:Shew_0430 histone family protein DNA-binding protein YP_001676016.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_0429 hypothetical protein YP_001676017.1 KEGG: shm:Shewmr7_3488 hypothetical protein YP_001676018.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: slo:Shew_0424 amino acid carrier protein YP_001676019.1 PFAM: major facilitator superfamily MFS_1; KEGG: slo:Shew_0420 major facilitator superfamily MFS_1 YP_001676020.1 KEGG: shn:Shewana3_2330 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001676021.1 TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter; KEGG: son:SO_0534 arsenical pump membrane protein, putative YP_001676022.1 PFAM: regulatory protein ArsR; KEGG: shm:Shewmr7_3499 transcriptional regulator, ArsR family YP_001676023.1 KEGG: azo:azo0052 hypothetical secreted protein YP_001676024.1 PFAM: peptidase U62 modulator of DNA gyrase; KEGG: sbm:Shew185_0512 peptidase U62 modulator of DNA gyrase YP_001676025.1 PFAM: protein of unknown function DUF615; KEGG: slo:Shew_0415 protein of unknown function DUF615 YP_001676026.1 PFAM: Ig domain protein group 1 domain protein; KEGG: sbl:Sbal_3807 Ig domain protein, group 1 domain protein YP_001676027.1 PFAM: ABC-2 type transporter; KEGG: sbm:Shew185_0508 ABC-2 type transporter YP_001676028.1 PFAM: ABC-2 type transporter; KEGG: she:Shewmr4_3462 ABC-2 type transporter YP_001676029.1 PFAM: secretion protein HlyD family protein; KEGG: shn:Shewana3_3639 secretion protein HlyD family protein YP_001676030.1 PFAM: outer membrane efflux protein; KEGG: slo:Shew_0411 outer membrane efflux protein YP_001676031.1 PFAM: peptidase U62 modulator of DNA gyrase; KEGG: she:Shewmr4_3465 peptidase U62, modulator of DNA gyrase YP_001676032.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: sbl:Sbal_3816 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001676033.1 KEGG: slo:Shew_0408 hypothetical protein YP_001676034.1 involved in the processing of the 5'end of 16S rRNA YP_001676035.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: slo:Shew_0406 maf protein YP_001676036.1 PFAM: Rod shape-determining protein MreD; KEGG: slo:Shew_0405 rod shape-determining protein MreD YP_001676037.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001676038.1 functions in MreBCD complex in some organisms YP_001676039.1 SMART: PA14-related domain protein; KEGG: slo:Shew_0402 MSHA biogenesis protein MshQ YP_001676040.1 KEGG: slo:Shew_0401 MSHA biogenesis protein MshP YP_001676041.1 KEGG: slo:Shew_0400 methylation site containing protein YP_001676042.1 KEGG: spc:Sputcn32_0570 methylation site containing protein YP_001676043.1 KEGG: saz:Sama_0462 MSHA pilin protein MshC YP_001676044.1 KEGG: slo:Shew_0397 methylation site containing protein YP_001676045.1 KEGG: son:SO_4105 MSHA pilin protein MshA YP_001676046.1 KEGG: shn:Shewana3_3657 methylation site containing protein YP_001676047.1 KEGG: slo:Shew_0394 hypothetical protein YP_001676048.1 PFAM: type II secretion system protein; KEGG: shw:Sputw3181_3608 type II secretion system protein YP_001676049.1 PFAM: type II secretion system protein E; General secretory system II protein E domain protein; KEGG: sbm:Shew185_0487 type II secretion system protein E YP_001676050.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: she:Shewmr4_3484 tetratricopeptide TPR_2 repeat protein YP_001676051.1 KEGG: she:Shewmr4_3485 MSHA biogenesis protein MshM YP_001676052.1 TIGRFAM: pilus (MSHA type) biogenesis protein MshL; PFAM: type II and III secretion system protein; Secretin domain protein; Secretin/TonB short domain; KEGG: slo:Shew_0389 pilus (MSHA type) biogenesis protein MshL YP_001676053.1 KEGG: shw:Sputw3181_3613 MSHA biogenesis protein MshK YP_001676054.1 KEGG: slo:Shew_0387 MSHA biogenesis protein MshJ YP_001676055.1 KEGG: slo:Shew_0386 fimbrial assembly family protein YP_001676056.1 KEGG: sbm:Shew185_0480 conserved hypothetical biogenesis protein MshI YP_001676057.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_001676058.1 PFAM: malic protein domain protein; malic protein NAD-binding; KEGG: slo:Shew_0383 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) YP_001676059.1 PFAM: nuclease (SNase domain protein); KEGG: slo:Shew_0382 nuclease (SNase domain protein) YP_001676060.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001676061.1 KEGG: slo:Shew_0380 hypothetical protein YP_001676062.1 KEGG: slo:Shew_0379 primosomal protein N'; TIGRFAM: primosomal protein N'; PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases YP_001676063.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001676064.1 PFAM: Sporulation domain protein; KEGG: slo:Shew_0377 sporulation domain protein YP_001676065.1 heat shock protein involved in degradation of misfolded proteins YP_001676066.1 heat shock protein involved in degradation of misfolded proteins YP_001676067.1 PFAM: protein of unknown function DUF971; KEGG: slo:Shew_0373 protein of unknown function DUF971 YP_001676068.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_001676069.1 PFAM: major facilitator superfamily MFS_1; KEGG: shn:Shewana3_2502 major facilitator superfamily MFS_1 YP_001676070.1 PFAM: cyclic nucleotide-binding; KEGG: shn:Shewana3_2501 cyclic nucleotide-binding protein YP_001676071.1 KEGG: hch:HCH_06317 GMP synthase - glutamine amidotransferase domain YP_001676072.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: hch:HCH_06318 alcohol dehydrogenase, class IV YP_001676073.1 PFAM: aldehyde dehydrogenase; KEGG: hch:HCH_06320 NAD-dependent aldehyde dehydrogenase YP_001676074.1 PFAM: glutamine synthetase catalytic region; KEGG: ppr:PBPRB0862 hypothetical protein YP_001676075.1 KEGG: slo:Shew_3369 hypothetical protein YP_001676076.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001676077.1 PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: slo:Shew_3372 arginase/agmatinase/formiminoglutamase YP_001676078.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: slo:Shew_3373 ubiquinone/menaquinone biosynthesis methyltransferase YP_001676079.1 PFAM: Sterol-binding domain protein; KEGG: slo:Shew_3374 protein of unknown function DUF1243 YP_001676080.1 TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: ABC-1 domain protein; KEGG: slo:Shew_3375 2-polyprenylphenol 6-hydroxylase YP_001676081.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: son:SO_4202 Sec-independent protein translocase protein TatA YP_001676082.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: slo:Shew_3377 twin-arginine translocation protein, TatB subunit YP_001676083.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: slo:Shew_3378 sec-independent protein translocase, TatC subunit YP_001676084.1 KEGG: shn:Shewana3_3731 hypothetical protein YP_001676085.1 PFAM: TatD-related deoxyribonuclease; KEGG: shw:Sputw3181_3671 TatD-related deoxyribonuclease YP_001676086.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Diverse 7TM receptor extracellular region 2; Diverse 7TM receptor transmembrane region; KEGG: slo:Shew_3381 diguanylate cyclase YP_001676087.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001676088.1 KEGG: shw:Sputw3181_0509 hypothetical protein YP_001676089.1 PFAM: TonB-dependent receptor; Cna B domain protein; TonB-dependent receptor plug; KEGG: saz:Sama_3213 putative oar protein YP_001676090.1 PFAM: Ppx/GppA phosphatase; KEGG: sbm:Shew185_3950 Ppx/GppA phosphatase YP_001676091.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_001676092.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: shn:Shewana3_0409 thioredoxin YP_001676093.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001676094.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_0336 transcriptional regulator, LysR family YP_001676095.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001676096.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001676097.1 PFAM: fumarate reductase respiratory complex transmembrane subunit; KEGG: sbm:Shew185_3961 fumarate reductase respiratory complex transmembrane subunit YP_001676098.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit YP_001676099.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001676100.1 TIGRFAM: putative TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase DuS; KEGG: slo:Shew_0330 putative TIM-barrel protein, nifR3 family YP_001676101.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_001676102.1 PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: shm:Shewmr7_3221 leucyl aminopeptidase YP_001676103.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: cps:CPS_1959 putative RND efflux system protein YP_001676104.1 PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: cps:CPS_1958 putative RND efflux system protein, MFP subunit YP_001676105.1 PFAM: outer membrane efflux protein; KEGG: cps:CPS_1957 putative RND efflux system protein YP_001676107.1 PFAM: Hemerythrin HHE cation binding domain protein; KEGG: sbm:Shew185_3967 hemerythrin HHE cation binding domain protein YP_001676108.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shn:Shewana3_0394 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_001676109.1 TIGRFAM: tyrosine recombinase XerC; PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: sbl:Sbal_3993 tyrosine recombinase XerC YP_001676110.1 PFAM: protein of unknown function DUF484; KEGG: slo:Shew_0324 protein of unknown function DUF484 YP_001676111.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001676112.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: slo:Shew_0322 diaminopimelate decarboxylase YP_001676113.1 KEGG: sbl:Sbal_3997 hypothetical protein YP_001676114.1 PFAM: Frataxin family protein; KEGG: sbm:Shew185_3976 frataxin family protein YP_001676115.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_001676116.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001676117.1 PFAM: Uroporphyrinogen III synthase HEM4; KEGG: spc:Sputcn32_3588 uroporphyrinogen III synthase HEM4 YP_001676118.1 PFAM: protein of unknown function DUF513 hemX; KEGG: slo:Shew_0316 protein of unknown function DUF513, HemX YP_001676119.1 PFAM: HemY domain protein; KEGG: slo:Shew_0315 HemY domain protein YP_001676120.1 KEGG: slo:Shew_0314 putative outer membrane adhesin like proteiin; TIGRFAM: putative outer membrane adhesin like proteiin; PFAM: Hemolysin-type calcium-binding region; SMART: Cadherin YP_001676121.1 TIGRFAM: putative outer membrane adhesin like proteiin; PFAM: Hemolysin-type calcium-binding region; von Willebrand factor type A; Cadherin; nucleic acid binding OB-fold tRNA/helicase-type; KEGG: shn:Shewana3_0382 putative outer membrane adhesin like proteiin YP_001676122.1 KEGG: slo:Shew_0312 ABC transporter-related protein; TIGRFAM: ABC transporter transmembrane region type 1; PFAM: ABC transporter related; peptidase C39 bacteriocin processing; SMART: AAA ATPase YP_001676123.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_0311 type I secretion membrane fusion protein, HlyD family YP_001676124.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: slo:Shew_0310 type I secretion outer membrane protein, TolC family YP_001676125.1 PFAM: OmpA/MotB domain protein; KEGG: slo:Shew_0309 OmpA/MotB domain protein YP_001676126.1 KEGG: shn:Shewana3_0377 hypothetical protein YP_001676127.1 PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase HAMP region domain protein; KEGG: slo:Shew_0307 diguanylate cyclase/phosphodiesterase YP_001676128.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: slo:Shew_0306 diguanylate cyclase/phosphodiesterase with GAF sensor YP_001676129.1 TIGRFAM: ATP-dependent DNA helicase Rep; PFAM: UvrD/REP helicase; KEGG: sbm:Shew185_3990 ATP-dependent DNA helicase Rep YP_001676130.1 PFAM: regulatory protein TetR; KEGG: son:SO_4326 transcriptional regulator, TetR family YP_001676131.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shn:Shewana3_0372 efflux transporter, RND family, MFP subunit YP_001676132.1 PFAM: acriflavin resistance protein; KEGG: shn:Shewana3_0371 acriflavin resistance protein YP_001676133.1 PFAM: protein of unknown function DUF526; KEGG: slo:Shew_0304 protein of unknown function DUF526 YP_001676134.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: slo:Shew_0302 phosphoesterase, PA-phosphatase related YP_001676135.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: slo:Shew_0301 transcriptional regulator, AsnC family YP_001676136.1 PFAM: sodium:neurotransmitter symporter; KEGG: slo:Shew_0300 sodium:neurotransmitter symporter YP_001676137.1 TIGRFAM: TonB-dependent copper receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: shm:Shewmr7_3408 TonB-dependent copper receptor YP_001676138.1 PFAM: aminotransferase class V; KEGG: shw:Sputw3181_3750 serine--pyruvate transaminase YP_001676139.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_001676140.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001676141.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001676142.1 KEGG: shw:Sputw3181_3753 amino acid-binding ACT domain protein YP_001676143.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_001676144.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001676145.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_001676146.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: slo:Shew_0285 diguanylate cyclase YP_001676147.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_1773 transcriptional regulator, LysR family YP_001676148.1 PFAM: regulatory protein LysR; KEGG: son:SO_3297 transcriptional regulator, LysR family YP_001676149.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: son:SO_3301 flavocytochrome c flavin subunit YP_001676150.1 KEGG: son:SO_3300 cytochrome c YP_001676151.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: son:SO_3299 Pal/histidase family protein YP_001676152.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; KEGG: vpa:VPA0596 putative methyl-accepting chemotaxis protein YP_001676153.1 KEGG: vha:VIBHAR_05569 hypothetical protein YP_001676154.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: vha:VIBHAR_05570 hypothetical protein YP_001676155.1 PFAM: histidine kinase A domain protein; KEGG: vha:VIBHAR_05571 hypothetical protein YP_001676157.1 KEGG: sbm:Shew185_1963 hypothetical protein YP_001676158.1 KEGG: sbl:Sbal_4042 Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001676159.1 PFAM: EAL domain protein; KEGG: swi:Swit_2925 EAL domain protein YP_001676160.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: slo:Shew_0282 phospholipid/glycerol acyltransferase YP_001676161.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: she:Shewmr4_3626 phospholipid/glycerol acyltransferase YP_001676163.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001676164.1 PFAM: regulatory protein TetR; KEGG: slo:Shew_0277 transcriptional regulator, TetR family YP_001676165.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: slo:Shew_0276 flavocytochrome c YP_001676166.1 KEGG: slo:Shew_0275 tetraheme cytochrome c, putative YP_001676167.1 KEGG: slo:Shew_0274 hypothetical protein YP_001676168.1 KEGG: son:SO_1411 hypothetical protein YP_001676169.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: slo:Shew_0272 cupin 2, conserved barrel domain protein YP_001676170.1 KEGG: vpa:VP1356 hypothetical protein YP_001676171.1 KEGG: vpa:VP1355 hypothetical protein YP_001676172.1 PFAM: alpha/beta hydrolase fold; KEGG: ppr:PBPRB0984 hypothetical protein YP_001676173.1 TIGRFAM: virulence-related outer membrane protein; KEGG: vco:VC0395_A1347 hypothetical protein YP_001676174.1 KEGG: slo:Shew_0271 phospholipase YP_001676175.1 KEGG: slo:Shew_0270 hypothetical protein YP_001676176.1 PFAM: Na+/H+ antiporter NhaC; KEGG: sbm:Shew185_4032 Na+ antiporter NhaC YP_001676177.1 PFAM: protein of unknown function DUF904; KEGG: slo:Shew_0267 protein of unknown function DUF904 YP_001676178.1 PFAM: protein of unknown function DUF1107; KEGG: son:SO_0334 hypothetical protein YP_001676179.1 PFAM: DSBA oxidoreductase; KEGG: slo:Shew_0265 DsbA oxidoreductase YP_001676180.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_001676181.1 KEGG: shn:Shewana3_3840 hypothetical protein YP_001676182.1 PFAM: protein of unknown function UPF0061; KEGG: she:Shewmr4_3645 protein of unknown function UPF0061 YP_001676183.1 KEGG: she:Shewmr4_3646 hypothetical protein YP_001676184.1 KEGG: slo:Shew_0260 hypothetical protein YP_001676185.1 KEGG: slo:Shew_0259 hypothetical protein YP_001676186.1 PFAM: response regulator receiver; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: vha:VIBHAR_05599 hypothetical protein YP_001676187.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: kra:Krad_0483 anti-sigma-factor antagonist YP_001676188.1 PFAM: Nucleotidyl transferase; KEGG: ava:Ava_3422 nucleotidyl transferase YP_001676189.1 KEGG: vpa:VPA1048 putative anti-sigma F factor antagonist YP_001676190.1 PFAM: glycosyl transferase family 2; KEGG: esa:ESA_01833 hypothetical protein YP_001676191.1 KEGG: ava:Ava_1569 hypothetical protein YP_001676192.1 KEGG: esa:ESA_01831 hypothetical protein YP_001676193.1 KEGG: esa:ESA_01830 hypothetical protein YP_001676195.1 KEGG: ppd:Ppro_2693 glycosyl transferase, family 2 YP_001676196.1 KEGG: vfi:VFA1013 hypothetical protein YP_001676197.1 KEGG: ana:alr3755 unknown protein YP_001676198.1 KEGG: esa:ESA_01836 hypothetical protein YP_001676200.1 KEGG: ppr:PBPRB1154 hypothetical protein YP_001676201.1 KEGG: ppr:PBPRB1153 hypothetical protein YP_001676202.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: vfi:VFA1016 sensory transduction protein kinase YP_001676203.1 KEGG: slo:Shew_0258 hypothetical protein YP_001676204.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: slo:Shew_0257 peptidase S9, prolyl oligopeptidase active site domain protein YP_001676205.1 KEGG: shn:Shewana3_3847 hypothetical protein YP_001676206.1 KEGG: slo:Shew_0246 hypothetical protein YP_001676207.1 PFAM: molydopterin dinucleotide-binding region; KEGG: slo:Shew_0245 molybdopterin dinucleotide-binding region YP_001676208.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: slo:Shew_0244 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001676209.1 PFAM: regulatory protein LysR; KEGG: slo:Shew_0243 transcriptional regulator, LysR family YP_001676210.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: slo:Shew_0242 molybdopterin dinucleotide-binding region YP_001676211.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: slo:Shew_0241 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001676212.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: slo:Shew_0240 cytoplasmic chaperone TorD family protein YP_001676213.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: slo:Shew_0239 formate dehydrogenase, gamma subunit YP_001676214.1 PFAM: porin Gram-negative type; KEGG: slo:Shew_0238 porin, gram-negative type YP_001676215.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: sbm:Shew185_2544 methyl-accepting chemotaxis sensory transducer YP_001676216.1 TIGRFAM: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; PFAM: lipid A biosynthesis acyltransferase; KEGG: vpa:VP1745 lipid A biosynthesis lauroyl acyltransferase YP_001676217.1 PFAM: regulatory protein LysR; KEGG: she:Shewmr4_3657 transcriptional regulator, LysR family YP_001676218.1 PFAM: Disulphide bond formation protein DsbB; KEGG: shm:Shewmr7_0287 disulphide bond formation protein DsbB YP_001676219.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: she:Shewmr4_3659 twin-arginine translocation pathway signal YP_001676220.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: she:Shewmr4_3660 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001676221.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: shm:Shewmr7_0284 cytoplasmic chaperone TorD family protein YP_001676222.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: she:Shewmr4_3662 formate dehydrogenase, gamma subunit YP_001676223.1 KEGG: slo:Shew_0238 porin, gram-negative type YP_001676224.1 PFAM: protein of unknown function DUF1232; KEGG: slo:Shew_0234 protein of unknown function DUF1232 YP_001676225.1 PFAM: Radical SAM domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: slo:Shew_0233 radical SAM N-terminal domain protein YP_001676226.1 KEGG: shn:Shewana3_3875 conserved hypothetical protein YP_001676227.1 PFAM: protein of unknown function DUF1212; KEGG: slo:Shew_0231 protein of unknown function DUF1212 YP_001676228.1 KEGG: slo:Shew_0230 hypothetical protein YP_001676229.1 KEGG: pat:Patl_2820 hypothetical protein YP_001676230.1 PFAM: small multidrug resistance protein; KEGG: sfr:Sfri_3425 small multidrug resistance protein YP_001676231.1 KEGG: sfr:Sfri_3426 carboxylesterase; TIGRFAM: S-formylglutathione hydrolase; PFAM: putative esterase YP_001676232.1 TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: son:SO_A0161 zinc-binding dehydrogenase YP_001676233.1 TIGRFAM: phage/conjugal plasmid C-4 type zinc finger protein, TraR family; PFAM: zinc finger DksA/TraR C4-type; KEGG: ilo:IL0756 DnaK suppressor protein YP_001676234.1 catalyzes the reaction of formaldehyde with glutathione to form S-hydroxymethylglutathione YP_001676235.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: son:SO_A0164 iron-containing alcohol dehydrogenase YP_001676236.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sfr:Sfri_3440 transcriptional regulator, LysR family protein YP_001676237.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: vfi:VF2364 NADH dehydrogenase YP_001676238.1 PFAM: Radical SAM domain protein; KEGG: pmu:PM0600 putative arylsulfatase regulator YP_001676239.1 KEGG: ent:Ent638_1505 protein of unknown function DUF1384 YP_001676240.1 PFAM: sulfatase; KEGG: stm:STM0035 putative arylsulfatase YP_001676241.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: ppr:PBPRB1790 hypothetical ABC transporter, substrate binding protein YP_001676242.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vha:VIBHAR_06563 hypothetical protein YP_001676243.1 KEGG: vha:VIBHAR_06564 hypothetical protein; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase YP_001676244.1 KEGG: slo:Shew_3355 hypothetical protein YP_001676245.1 KEGG: sma:SAV4441 hypothetical protein YP_001676246.1 KEGG: spc:Sputcn32_3933 hypothetical protein YP_001676247.1 KEGG: spc:Sputcn32_3932 hypothetical protein YP_001676248.1 PFAM: Prophage CP4-57 regulatory; KEGG: vvy:VV0810 predicted transcriptional regulator YP_001676249.1 KEGG: slo:Shew_1265 hypothetical protein YP_001676251.1 KEGG: neu:NE0256 hypothetical protein YP_001676252.1 KEGG: eba:p1D12 weak: Alr7543 protein YP_001676257.1 KEGG: pcr:Pcryo_1614 hypothetical protein YP_001676258.1 PFAM: integrase family protein; KEGG: son:SO_3884 site-specific recombinase, phage integrase family YP_001676259.1 PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: pat:Patl_0729 AAA ATPase, central region YP_001676260.1 KEGG: sbl:Sbal_3560 hypothetical protein YP_001676261.1 KEGG: she:Shewmr4_3221 hypothetical protein YP_001676262.1 KEGG: she:Shewmr4_3199 hypothetical protein YP_001676263.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: par:Psyc_0401 probable C-5 cytosine-specific DNA methylase YP_001676264.1 KEGG: par:Psyc_0402 hypothetical protein YP_001676265.1 PFAM: integrase family protein; KEGG: pat:Patl_0725 phage integrase YP_001676266.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: slo:Shew_0228 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase YP_001676267.1 PFAM: LppC family lipoprotein; KEGG: slo:Shew_0227 LppC family lipoprotein YP_001676268.1 PFAM: protein of unknown function UPF0102; KEGG: sbm:Shew185_4070 protein of unknown function UPF0102 YP_001676269.1 TIGRFAM: phosphoheptose isomerase; KEGG: shw:Sputw3181_3836 phosphoheptose isomerase YP_001676270.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: slo:Shew_0224 transport-associated YP_001676271.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sfr:Sfri_0385 protein of unknown function DUF6, transmembrane YP_001676272.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sfr:Sfri_0384 transcriptional regulator, LysR family protein YP_001676273.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001676274.1 TIGRFAM: phosphoglycolate phosphatase ; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shw:Sputw3181_3841 phosphoglycolate phosphatase YP_001676275.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: slo:Shew_0219 ribulose-phosphate 3-epimerase YP_001676276.1 KEGG: slo:Shew_0218 hypothetical protein YP_001676277.1 KEGG: spc:Sputcn32_3702 hypothetical protein YP_001676278.1 KEGG: slo:Shew_0216 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_001676279.1 PFAM: Sporulation domain protein; KEGG: slo:Shew_0215 sporulation domain protein YP_001676280.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001676281.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001676282.1 TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; Secretin/TonB short domain; KEGG: slo:Shew_0212 type IV pilus secretin PilQ YP_001676283.1 PFAM: Pilus assembly protein PilP; KEGG: sbm:Shew185_4086 pilus assembly protein PilP YP_001676284.1 PFAM: Pilus assembly protein PilO; KEGG: slo:Shew_0210 pilus assembly protein, PilO YP_001676285.1 PFAM: Fimbrial assembly family protein; KEGG: slo:Shew_0209 fimbrial assembly family protein YP_001676286.1 TIGRFAM: type IV pilus assembly protein PilM; KEGG: slo:Shew_0208 type IV pilus assembly protein PilM YP_001676287.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: sbm:Shew185_4090 penicillin-binding protein, 1A family YP_001676288.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001676289.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001676290.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001676291.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001676292.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001676293.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_001676294.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001676295.1 PFAM: protein of unknown function DUF1439; KEGG: slo:Shew_0199 protein of unknown function DUF1439 YP_001676296.1 TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: shw:Sputw3181_3863 competence/damage-inducible protein CinA YP_001676297.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: slo:Shew_0196 redoxin domain protein YP_001676298.1 PFAM: cytochrome C biogenesis protein; KEGG: slo:Shew_0195 cytochrome c biogenesis protein YP_001676299.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sbm:Shew185_0232 periplasmic protein thiol--disulphide oxidoreductase DsbE YP_001676300.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: shm:Shewmr7_0229 cytochrome c-type biogenesis protein CcmF YP_001676301.1 SMART: Tetratricopeptide domain protein; KEGG: slo:Shew_0192 TPR repeat-containing protein YP_001676302.1 PFAM: cytochrome c class I; KEGG: sfr:Sfri_0180 cytochrome c, class I YP_001676303.1 ATP-binding protein; required for proper cytochrome c maturation YP_001676304.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: sbm:Shew185_0227 heme exporter protein CcmB YP_001676305.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein; KEGG: slo:Shew_0188 heme exporter protein CcmC YP_001676306.1 PFAM: Heme exporter protein D (CcmD); KEGG: son:SO_0260 heme exporter protein CcmD YP_001676307.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001676308.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001676309.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001676310.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001676311.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001676312.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001676313.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001676314.1 late assembly protein YP_001676315.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001676316.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001676317.1 binds 5S rRNA along with protein L5 and L25 YP_001676318.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001676319.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001676320.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001676321.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001676322.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001676323.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001676324.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001676325.1 one of the stabilizing components for the large ribosomal subunit YP_001676326.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001676327.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001676328.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001676329.1 TIGRFAM: ribosomal protein S19; PFAM: ribosomal protein S19/S15; KEGG: slo:Shew_0162 ribosomal protein S19 YP_001676330.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001676331.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001676332.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001676333.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001676334.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001676335.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001676336.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001676337.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001676338.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001676339.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001676340.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001676341.1 TIGRFAM: ribosomal protein L7/L12; PFAM: Ribosomal protein L7/L12; KEGG: sfr:Sfri_0140 ribosomal protein L7/L12 YP_001676342.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001676343.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001676344.1 binds directly to 23S ribosomal RNA YP_001676345.1 TIGRFAM: transcription termination/antitermination factor NusG; PFAM: KOW domain protein; NGN domain protein; KEGG: slo:Shew_0146 NusG antitermination factor YP_001676346.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001676347.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001676348.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001676349.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001676350.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001676351.1 PFAM: RNP-1 like RNA-binding protein; KEGG: slo:Shew_0140 RNP-1-like RNA-binding protein YP_001676352.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001676353.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_001676354.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_001676355.1 PFAM: fatty acid desaturase; KEGG: shw:Sputw3181_3679 stearoyl-CoA 9-desaturase YP_001676356.1 catalyzes the formation of selenophosphate from selenide and ATP YP_001676357.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_001676358.1 PFAM: major facilitator superfamily MFS_1; KEGG: shn:Shewana3_0173 phospholipid/glycerol acyltransferase YP_001676359.1 PFAM: GCN5-related N-acetyltransferase; KEGG: slo:Shew_0131 GCN5-related N-acetyltransferase YP_001676360.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: sbl:Sbal_4187 3'(2'),5'-bisphosphate nucleotidase YP_001676361.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001676362.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: spc:Sputcn32_3556 HAD-superfamily hydrolase, subfamily IA, variant 3 YP_001676363.1 PFAM: type II secretion system protein N; KEGG: slo:Shew_3609 type II secretion system protein N YP_001676364.1 PFAM: General secretion pathway M protein; KEGG: slo:Shew_3610 general secretion pathway M protein YP_001676365.1 TIGRFAM: general secretion pathway protein L; PFAM: General secretion pathway L; KEGG: shm:Shewmr7_0159 general secretion pathway protein L YP_001676366.1 PFAM: General secretion pathway protein K; KEGG: slo:Shew_3612 general secretion pathway protein K YP_001676367.1 TIGRFAM: general secretion pathway protein J; KEGG: shn:Shewana3_0157 general secretion pathway protein J YP_001676368.1 TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: slo:Shew_3614 general secretion pathway protein I YP_001676369.1 TIGRFAM: general secretion pathway protein H; KEGG: slo:Shew_3615 general secretion pathway protein H YP_001676370.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: slo:Shew_3616 general secretion pathway protein G YP_001676371.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein; KEGG: slo:Shew_3617 general secretion pathway protein F YP_001676372.1 KEGG: slo:Shew_3618 general secretory pathway protein E; TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001676373.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: slo:Shew_3619 general secretion pathway protein D YP_001676374.1 TIGRFAM: general secretion pathway protein C; KEGG: slo:Shew_3620 general secretion pathway protein C YP_001676375.1 PFAM: RNA-binding S4 domain protein; KEGG: slo:Shew_3621 RNA-binding S4 domain protein YP_001676376.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001676377.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001676378.1 KEGG: slo:Shew_3626 hypothetical protein YP_001676379.1 PFAM: helix-turn-helix domain protein; KEGG: ccr:CC_2232 transcriptional regulator, Cro/CI family YP_001676380.1 PFAM: peptidase M14 carboxypeptidase A; KEGG: sbl:Sbal_4213 peptidase M14, carboxypeptidase A YP_001676381.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: sbm:Shew185_0141 methyltransferase type 12 YP_001676382.1 KEGG: shn:Shewana3_0138 lipoprotein, putative YP_001676383.1 KEGG: cps:CPS_0009 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein YP_001676384.1 PFAM: Excinuclease ABC C subunit domain protein; KEGG: she:Shewmr4_0137 excinuclease ABC, C subunit domain protein YP_001676385.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: she:Shewmr4_0136 oligopeptidase B YP_001676386.1 DHBP synthase; functions during riboflavin biosynthesis YP_001676387.1 KEGG: shn:Shewana3_0133 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase HAMP region domain protein; Nitrate and nitrite sensing domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001676388.1 PFAM: Ferritin Dps family protein; KEGG: slo:Shew_0042 ferritin, Dps family protein YP_001676389.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; MoeA domain protein domain IV; KEGG: slo:Shew_0046 molybdenum cofactor synthesis domain protein YP_001676390.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001676391.1 PFAM: Ankyrin; KEGG: sbm:Shew185_0251 ankyrin YP_001676392.1 PFAM: Catalase domain protein; KEGG: sbm:Shew185_0250 catalase YP_001676393.1 PFAM: protein of unknown function DUF333; KEGG: saz:Sama_1095 conserved hypothetical protein YP_001676395.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: pfl:PFL_3947 ECF sigma factor PrtI YP_001676396.1 KEGG: cvi:CV_3514 hypothetical protein YP_001676397.1 PFAM: protein of unknown function DUF692; KEGG: shn:Shewana3_0975 protein of unknown function DUF692 YP_001676398.1 KEGG: cps:CPS_0845 hypothetical protein YP_001676399.1 PFAM: sodium/glutamate symporter; KEGG: slo:Shew_0103 sodium/glutamate symporter YP_001676400.1 KEGG: vha:VIBHAR_05692 hypothetical protein YP_001676401.1 PFAM: glycosyl transferase family 25; KEGG: par:Psyc_1207 probable glycosyl transferase family 25, LPS biosynthesis YP_001676402.1 PFAM: glycosyl transferase group 1; KEGG: shn:Shewana3_4093 glycosyl transferase, group 1 YP_001676403.1 PFAM: glycosyl transferase family 2; KEGG: spc:Sputcn32_3892 glycosyl transferase, family 2 YP_001676404.1 PFAM: polysaccharide pyruvyl transferase; KEGG: apl:APL_1030 hypothetical protein YP_001676405.1 PFAM: glycosyl transferase family 2; KEGG: cjr:CJE1280 lipooligosaccharide biosynthesis galactosyltransferase, putative YP_001676406.1 PFAM: glycosyl transferase family 25; KEGG: vpa:VP0210 putative Lex2B YP_001676407.1 PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; KEGG: sbm:Shew185_4334 CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase YP_001676408.1 PFAM: glycosyl transferase group 1; KEGG: sbm:Shew185_4335 glycosyl transferase group 1 YP_001676409.1 KEGG: sbl:Sbal_0063 hypothetical protein YP_001676410.1 PFAM: glycosyl transferase family 9; KEGG: slo:Shew_3702 glycosyl transferase, family 9 YP_001676411.1 catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position YP_001676412.1 PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain protein; KEGG: shw:Sputw3181_0052 three-deoxy-D-manno-octulosonic-acid transferase domain protein YP_001676413.1 PFAM: regulatory protein TetR; KEGG: spc:Sputcn32_3900 transcriptional regulator, TetR family YP_001676414.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_001676415.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_001676416.1 PFAM: Rhodanese domain protein; KEGG: sfr:Sfri_3940 rhodanese domain protein YP_001676417.1 PFAM: Rhomboid family protein; KEGG: slo:Shew_3712 rhomboid family protein YP_001676418.1 PFAM: ThiJ/PfpI domain protein; KEGG: son:SO_4670 enhancing lycopene biosynthesis protein YP_001676419.1 KEGG: slo:Shew_3714 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: Helix-hairpin-helix domain protein class 2 YP_001676420.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001676421.1 PFAM: cytochrome c class I; KEGG: spc:Sputcn32_3908 cytochrome c, class I YP_001676422.1 KEGG: slo:Shew_3717 hypothetical protein YP_001676423.1 PFAM: protein of unknown function DUF414; KEGG: slo:Shew_3718 hypothetical protein YP_001676424.1 KEGG: sbm:Shew185_4350 hypothetical protein YP_001676425.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001676426.1 PFAM: protein of unknown function DUF885; KEGG: slo:Shew_3722 protein of unknown function DUF885 YP_001676427.1 PFAM: alpha/beta hydrolase fold; KEGG: shn:Shewana3_4119 alpha/beta hydrolase fold YP_001676428.1 TIGRFAM: flagellar biosynthesis protein FlhA; PFAM: type III secretion FHIPEP protein; KEGG: shw:Sputw3181_0454 flagellar biosynthesis protein FlhA YP_001676429.1 TIGRFAM: flagellar biosynthetic protein FlhB; PFAM: type III secretion exporter; KEGG: sbl:Sbal_3987 flagellar biosynthetic protein FlhB YP_001676430.1 TIGRFAM: flagellar biosynthetic protein FliR; PFAM: type III secretion system inner membrane R protein; KEGG: sbl:Sbal_3986 flagellar biosynthetic protein FliR YP_001676431.1 PFAM: export protein FliQ family 3; KEGG: sbl:Sbal_3985 export protein FliQ, family 3 YP_001676432.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001676433.1 TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; KEGG: shw:Sputw3181_0459 flagellar motor switch protein FliN YP_001676434.1 KEGG: sbl:Sbal_3982 hypothetical protein YP_001676435.1 PFAM: OmpA/MotB domain protein; KEGG: vha:VIBHAR_04970 hypothetical protein YP_001676436.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: shw:Sputw3181_0461 sigma54 specific transcriptional regulator, fis family YP_001676437.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: sbl:Sbal_3980 flagellar hook-basal body complex subunit FliE YP_001676438.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; the Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001676439.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001676440.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001676441.1 KEGG: sbl:Sbal_3976 ATPase, FliI/YscN family; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; SMART: AAA ATPase YP_001676442.1 KEGG: sdn:Sden_3655 hypothetical protein YP_001676443.1 KEGG: shw:Sputw3181_0468 hypothetical protein YP_001676444.1 KEGG: shw:Sputw3181_0469 hypothetical protein YP_001676445.1 KEGG: sbl:Sbal_3972 SAF domain YP_001676446.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001676447.1 TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: protein of unknown function DUF1078 domain protein; KEGG: sdn:Sden_3650 flagellar basal-body rod protein FlgC YP_001676448.1 PFAM: flagellar hook capping protein; KEGG: sdn:Sden_3649 flagellar hook capping protein YP_001676449.1 the hook connects flagellar basal body to the flagellar filament; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001676450.1 TIGRFAM: flagellar basal-body rod protein FlgF; PFAM: flagellar basal body rod protein; KEGG: sbl:Sbal_3967 flagellar basal-body rod protein FlgF YP_001676451.1 TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: shw:Sputw3181_0476 flagellar basal-body rod protein FlgG YP_001676452.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_001676453.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001676454.1 FlgJ; flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; like the lateral flagella FlgJ in Vibrio parahaemolyticus this protein does not contains a C-terminal muramidase domain YP_001676455.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: sbl:Sbal_3962 flagellar hook-associated protein FlgK YP_001676456.1 TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: spc:Sputcn32_3458 flagellar hook-associated protein 3 YP_001676457.1 KEGG: sbl:Sbal_3960 hypothetical protein YP_001676458.1 PFAM: protein of unknown function UPF0153; KEGG: sbl:Sbal_3863 flagellar biosynthesis protein, putative YP_001676459.1 PFAM: flagellin domain protein; KEGG: shw:Sputw3181_0483 flagellin domain protein YP_001676460.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; KEGG: sbl:Sbal_3955 flagellar hook-associated 2 domain protein YP_001676461.1 PFAM: flagellar protein FliS; KEGG: shw:Sputw3181_0486 flagellar protein FliS YP_001676462.1 KEGG: sbl:Sbal_3953 hypothetical protein YP_001676463.1 PFAM: flagellar hook-length control protein; KEGG: sbl:Sbal_3952 flagellar hook-length control protein YP_001676464.1 PFAM: flagellar basal body-associated protein FliL; KEGG: sdn:Sden_3634 flagellar basal body-associated protein FliL YP_001676465.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001676466.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: sdn:Sden_3632 MotA/TolQ/ExbB proton channel YP_001676467.1 PFAM: OmpA/MotB domain protein; KEGG: sdn:Sden_3631 OmpA/MotB YP_001676468.1 KEGG: sdn:Sden_3630 type IV pilus assembly PilZ YP_001676469.1 KEGG: shw:Sputw3181_0494 hypothetical protein YP_001676470.1 TIGRFAM: Cytochrome c oxidase cbb3 type accessory protein FixG; KEGG: slo:Shew_3812 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001676471.1 KEGG: sbm:Shew185_4357 hypothetical protein YP_001676472.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_001676473.1 KEGG: shn:Shewana3_4124 hypothetical protein YP_001676474.1 PFAM: sodium/hydrogen exchanger; KEGG: slo:Shew_3170 sodium/hydrogen exchanger YP_001676475.1 TIGRFAM: phosphate binding protein; KEGG: son:SO_4292 phosphate ABC transporter, periplasmic phosphate-binding protein YP_001676476.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO_4291 phosphate ABC transporter, permease protein YP_001676477.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO_4290 phosphate ABC transporter, permease protein YP_001676478.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001676479.1 KEGG: cps:CPS_2434 hypothetical protein YP_001676480.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_001676481.1 PFAM: regulatory protein LuxR; KEGG: vvu:VV2_1396 DNA-binding HTH domain-containing protein YP_001676482.1 KEGG: cps:CPS_0108 hypothetical protein YP_001676483.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: ppr:PBPRA3023 hypothetical sigma-54 modulation protein YP_001676484.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001676485.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: sbm:Shew185_4361 transcriptional regulator, DeoR family YP_001676486.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: slo:Shew_3841 TonB-dependent siderophore receptor YP_001676487.1 TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; KEGG: slo:Shew_3842 UDP-N-acetylglucosamine pyrophosphorylase YP_001676488.1 PFAM: DsrE family protein; KEGG: slo:Shew_3843 DsrE family protein YP_001676489.1 PFAM: protein of unknown function DUF214; KEGG: gvi:glr1418 putative ABC transport system permease protein YP_001676490.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sus:Acid_6481 ABC transporter related YP_001676491.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: sus:Acid_6482 efflux transporter, RND family, MFP subunit YP_001676492.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001676493.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001676494.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001676495.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001676496.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001676497.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001676498.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001676499.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001676500.1 PFAM: ATP synthase I chain; KEGG: slo:Shew_3852 ATP synthase I chain YP_001676501.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: saz:Sama_3652 ParB family protein YP_001676502.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: slo:Shew_3854 cobyrinic acid a,c-diamide synthase YP_001676503.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001676504.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001676505.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001676506.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: slo:Shew_3859 inosine/uridine-preferring nucleoside hydrolase YP_001676507.1 PFAM: SEC-C motif domain protein; KEGG: cps:CPS_2413 SEC-C motif domain protein YP_001676508.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sfr:Sfri_3118 lysine exporter protein (LysE/YggA) YP_001676509.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001676510.1 PFAM: 60 kDa inner membrane insertion protein; KEGG: slo:Shew_3866 60 kDa inner membrane insertion protein YP_001676511.1 PFAM: protein of unknown function DUF37; KEGG: shw:Sputw3181_4093 protein of unknown function DUF37 YP_001676512.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001676513.1 in Escherichia coli transcription of this gene is enhanced by polyamines