-- dump date 20140620_064230 -- class Genbank::CDS -- table cds_note -- id note YP_001499865.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001499866.1 KEGG: slo:Shew_0002 DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta chain YP_001499867.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001499868.1 KEGG: shw:Sputw3181_0004 DNA gyrase, B subunit; TIGRFAM: DNA gyrase, B subunit; PFAM: DNA gyrase subunit B domain protein; ATP-binding region ATPase domain protein; TOPRIM domain protein; DNA topoisomerase type IIA subunit B region 2 domain protein; SMART: DNA topoisomerase II YP_001499869.1 PFAM: Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region; KEGG: shn:Shewana3_0015 putative signal transduction protein YP_001499870.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001499871.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001499872.1 KEGG: slo:Shew_0011 DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase YP_001499873.1 KEGG: slo:Shew_0012 hypothetical protein YP_001499874.1 PFAM: peptidase S9B dipeptidylpeptidase IV domain protein; amidohydrolase; WD40 domain protein beta Propeller; KEGG: slo:Shew_0013 amidohydrolase YP_001499875.1 KEGG: she:Shewmr4_0012 hypothetical protein YP_001499876.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_001499877.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: vfi:VF1792 regulatory protein YP_001499878.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ppr:PBPRB1061 hypothetical protein YP_001499879.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3340 integrase, catalytic region YP_001499880.1 KEGG: mmw:Mmwyl1_3491 transposase YP_001499881.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001499882.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001499883.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_001499884.1 PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: slo:Shew_0021 protein of unknown function UPF0029 YP_001499885.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: slo:Shew_0022 potassium uptake protein, TrkH family YP_001499886.1 KEGG: slo:Shew_0023 protoporphyrinogen oxidase YP_001499887.1 KEGG: mmw:Mmwyl1_3491 transposase YP_001499888.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3340 integrase, catalytic region YP_001499889.1 PFAM: regulatory protein ArsR; KEGG: shw:Sputw3181_0018 regulatory protein, ArsR YP_001499890.1 KEGG: slo:Shew_0025 protoporphyrinogen oxidase YP_001499891.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: slo:Shew_3740 potassium uptake protein, TrkH family YP_001499892.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001499893.1 TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: sbl:Sbal_0030 sun protein YP_001499894.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: shm:Shewmr7_0026 methionyl-tRNA formyltransferase YP_001499895.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001499896.1 PFAM: Peptidoglycan-binding LysM; KEGG: slo:Shew_3735 peptidoglycan-binding LysM YP_001499897.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: shw:Sputw3181_0026 DNA protecting protein DprA YP_001499898.1 PFAM: protein of unknown function DUF494; KEGG: shw:Sputw3181_0027 protein of unknown function DUF494 YP_001499899.1 PFAM: Peptidase M9A collagenase domain protein; KEGG: slo:Shew_3732 microbial collagenase YP_001499900.1 PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: sbm:Shew185_0031 DNA topoisomerase type IA zn finger domain protein YP_001499901.1 PFAM: SUA5/yciO/yrdC domain; KEGG: sbm:Shew185_0032 SUA5/YciO/YrdC/YwlC family protein YP_001499902.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001499903.1 PFAM: globin; KEGG: shm:Shewmr7_0034 globin YP_001499904.1 TIGRFAM: shikimate 5-dehydrogenase; PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding domain protein; KEGG: slo:Shew_3727 shikimate 5-dehydrogenase YP_001499905.1 PFAM: protein of unknown function DUF1488; KEGG: shn:Shewana3_0044 protein of unknown function DUF1488 YP_001499906.1 KEGG: son:SO_0042 carbonic anhydrase, family 3 YP_001499907.1 KEGG: sbl:Sbal_2968 protein of unknown function DUF115 YP_001499908.1 KEGG: shn:Shewana3_1310 hypothetical protein YP_001499909.1 PFAM: protein of unknown function DUF115; KEGG: sbl:Sbal_2956 protein of unknown function DUF115 YP_001499910.1 PFAM: polysaccharide biosynthesis protein CapD; KEGG: vfi:VF0140 UDP-N-acetylglucosamine 4,6-dehydratase YP_001499911.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: vha:VIBHAR_00668 hypothetical protein YP_001499912.1 PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: vpa:VP0199 putative NeuC YP_001499913.1 PFAM: N-acetylneuraminic acid synthase domain; KEGG: vfi:VF0143 N-acetylneuraminate synthase YP_001499914.1 KEGG: vfi:VF0144 sialic acid biosynthesis protein NeuD YP_001499915.1 PFAM: CBS domain containing protein; Nucleotidyl transferase; KEGG: vfi:VF0145 mannose-1-phosphate guanyltransferase YP_001499916.1 PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; acylneuraminate cytidylyltransferase; KEGG: vha:VIBHAR_00677 hypothetical protein YP_001499917.1 KEGG: sdn:Sden_3629 hypothetical protein YP_001499918.1 KEGG: shw:Sputw3181_0493 type IV pilus assembly PilZ YP_001499919.1 PFAM: OmpA/MotB domain protein; KEGG: sdn:Sden_3631 OmpA/MotB YP_001499920.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: sdn:Sden_3632 MotA/TolQ/ExbB proton channel YP_001499921.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001499922.1 PFAM: flagellar basal body-associated protein FliL; KEGG: sdn:Sden_3634 flagellar basal body-associated protein FliL YP_001499923.1 PFAM: flagellar hook-length control protein; KEGG: sdn:Sden_3635 flagellar hook-length control protein YP_001499924.1 KEGG: sbl:Sbal_3953 hypothetical protein YP_001499925.1 PFAM: flagellar protein FliS; KEGG: sbl:Sbal_3954 flagellar protein FliS YP_001499926.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; KEGG: sbl:Sbal_3955 flagellar hook-associated 2 domain protein YP_001499927.1 PFAM: flagellin domain protein; KEGG: sbl:Sbal_3957 flagellin domain protein YP_001499928.1 KEGG: spc:Sputcn32_3457 hypothetical protein YP_001499929.1 TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: spc:Sputcn32_3458 flagellar hook-associated protein 3 YP_001499930.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: sbl:Sbal_3962 flagellar hook-associated protein FlgK YP_001499931.1 FlgJ; flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; like the lateral flagella FlgJ in Vibrio parahaemolyticus this protein does not contains a C-terminal muramidase domain YP_001499932.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001499933.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_001499934.1 TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: shw:Sputw3181_0476 flagellar basal-body rod protein FlgG YP_001499935.1 TIGRFAM: flagellar basal-body rod protein FlgF; PFAM: flagellar basal body rod protein; KEGG: shw:Sputw3181_0475 flagellar basal-body rod protein FlgF YP_001499936.1 the hook connects flagellar basal body to the flagellar filament; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001499937.1 PFAM: flagellar hook capping protein; KEGG: sbl:Sbal_3969 flagellar hook capping protein YP_001499938.1 TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: protein of unknown function DUF1078 domain protein; KEGG: shw:Sputw3181_0472 flagellar basal-body rod protein FlgC YP_001499939.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001499940.1 PFAM: SAF domain protein; KEGG: shw:Sputw3181_0470 SAF domain YP_001499941.1 KEGG: shw:Sputw3181_0469 hypothetical protein YP_001499942.1 KEGG: shw:Sputw3181_0468 hypothetical protein YP_001499943.1 KEGG: shw:Sputw3181_0467 hypothetical protein YP_001499944.1 KEGG: sbl:Sbal_3976 ATPase, FliI/YscN family; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; SMART: AAA ATPase YP_001499945.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001499946.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001499947.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; the Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001499948.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: sbl:Sbal_3980 flagellar hook-basal body complex subunit FliE YP_001499949.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: shw:Sputw3181_0461 sigma54 specific transcriptional regulator, fis family YP_001499950.1 PFAM: OmpA/MotB domain protein; KEGG: ppr:PBPRA0019 hypothetical protein YP_001499951.1 KEGG: sbl:Sbal_3982 hypothetical protein YP_001499952.1 TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; KEGG: shw:Sputw3181_0459 flagellar motor switch protein FliN YP_001499953.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001499954.1 TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ family 3; KEGG: sbl:Sbal_3985 export protein FliQ, family 3 YP_001499955.1 TIGRFAM: flagellar biosynthetic protein FliR; PFAM: type III secretion system inner membrane R protein; KEGG: spc:Sputcn32_3483 flagellar biosynthetic protein FliR YP_001499956.1 TIGRFAM: flagellar biosynthetic protein FlhB; PFAM: type III secretion exporter; KEGG: shw:Sputw3181_0455 flagellar biosynthetic protein FlhB YP_001499957.1 TIGRFAM: flagellar biosynthesis protein FlhA; PFAM: type III secretion FHIPEP protein; KEGG: shw:Sputw3181_0454 flagellar biosynthesis protein FlhA YP_001499958.1 PFAM: alpha/beta hydrolase fold; KEGG: shn:Shewana3_4119 alpha/beta hydrolase fold YP_001499959.1 PFAM: protein of unknown function DUF885; KEGG: shn:Shewana3_4118 protein of unknown function DUF885 YP_001499960.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001499961.1 KEGG: slo:Shew_3719 hypothetical protein YP_001499962.1 PFAM: protein of unknown function DUF414; KEGG: slo:Shew_3718 hypothetical protein YP_001499963.1 KEGG: slo:Shew_3717 hypothetical protein YP_001499964.1 PFAM: cytochrome c class I; KEGG: spc:Sputcn32_3908 cytochrome c, class I YP_001499965.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001499966.1 KEGG: slo:Shew_3714 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: Helix-hairpin-helix domain protein class 2 YP_001499967.1 PFAM: ThiJ/PfpI domain protein; KEGG: shw:Sputw3181_0046 ThiJ/PfpI domain protein YP_001499968.1 PFAM: Rhomboid family protein; KEGG: shw:Sputw3181_0047 rhomboid family protein YP_001499969.1 PFAM: Rhodanese domain protein; KEGG: sfr:Sfri_3940 rhodanese domain protein YP_001499970.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_001499971.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_001499972.1 PFAM: regulatory protein TetR; KEGG: spc:Sputcn32_3900 transcriptional regulator, TetR family YP_001499973.1 PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain protein; KEGG: shw:Sputw3181_0052 three-deoxy-D-manno-octulosonic-acid transferase domain protein YP_001499974.1 catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position YP_001499975.1 PFAM: glycosyl transferase family 9; KEGG: slo:Shew_3702 glycosyl transferase, family 9 YP_001499976.1 KEGG: sbl:Sbal_0063 hypothetical protein YP_001499977.1 PFAM: glycosyl transferase group 1; KEGG: sbm:Shew185_4335 glycosyl transferase group 1 YP_001499978.1 PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; KEGG: shm:Shewmr7_3986 CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase YP_001499979.1 PFAM: glycosyl transferase group 1; KEGG: shm:Shewmr7_3984 glycosyl transferase, group 1 YP_001499980.1 PFAM: glycosyl transferase family 25; KEGG: par:Psyc_1207 probable glycosyl transferase family 25, LPS biosynthesis YP_001499981.1 KEGG: sbl:Sbal_0299 hypothetical protein YP_001499982.1 PFAM: sodium/glutamate symporter; KEGG: slo:Shew_0103 sodium/glutamate symporter YP_001499983.1 KEGG: cps:CPS_0845 hypothetical protein YP_001499984.1 PFAM: protein of unknown function DUF692; KEGG: sbm:Shew185_3392 protein of unknown function DUF692 YP_001499985.1 KEGG: cvi:CV_3514 hypothetical protein YP_001499986.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: pde:Pden_4558 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001499988.1 PFAM: protein of unknown function DUF333; KEGG: sbm:Shew185_0128 protein of unknown function DUF333 YP_001499989.1 PFAM: Catalase domain protein; KEGG: sbm:Shew185_0250 catalase YP_001499990.1 KEGG: sbm:Shew185_0251 ankyrin YP_001499991.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001499992.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; MoeA domain protein domain IV; KEGG: slo:Shew_0046 molybdenum cofactor synthesis domain protein YP_001499993.1 PFAM: Ferritin Dps family protein; KEGG: slo:Shew_0042 ferritin, Dps family protein YP_001499994.1 KEGG: sbm:Shew185_0133 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase HAMP region domain protein; Nitrate and nitrite sensing domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001499995.1 DHBP synthase; functions during riboflavin biosynthesis YP_001499996.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: she:Shewmr4_0136 oligopeptidase B YP_001499997.1 PFAM: Excinuclease ABC C subunit domain protein; KEGG: sbl:Sbal_4217 excinuclease ABC, C subunit domain protein YP_001499998.1 KEGG: sde:Sde_0576 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein YP_001499999.1 KEGG: shm:Shewmr7_0138 lipoprotein, putative YP_001500000.1 PFAM: thiopurine S-methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: sbm:Shew185_0141 methyltransferase type 12 YP_001500001.1 PFAM: peptidase M14 carboxypeptidase A; KEGG: sbl:Sbal_4213 peptidase M14, carboxypeptidase A YP_001500002.1 PFAM: helix-turn-helix domain protein; KEGG: ccr:CC_2232 transcriptional regulator, Cro/CI family YP_001500003.1 KEGG: slo:Shew_3626 hypothetical protein YP_001500004.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001500005.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001500006.1 PFAM: RNA-binding S4 domain protein; KEGG: slo:Shew_3621 RNA-binding S4 domain protein YP_001500007.1 TIGRFAM: general secretion pathway protein C; KEGG: slo:Shew_3620 general secretion pathway protein C YP_001500008.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: slo:Shew_3619 general secretion pathway protein D YP_001500009.1 KEGG: slo:Shew_3618 general secretory pathway protein E; TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001500010.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein; KEGG: slo:Shew_3617 general secretion pathway protein F YP_001500011.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: slo:Shew_3616 general secretion pathway protein G YP_001500012.1 TIGRFAM: general secretion pathway protein H; KEGG: slo:Shew_3615 general secretion pathway protein H YP_001500013.1 TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: slo:Shew_3614 general secretion pathway protein I YP_001500014.1 TIGRFAM: general secretion pathway protein J; KEGG: sbl:Sbal_4200 general secretion pathway protein J YP_001500015.1 PFAM: General secretion pathway protein K; KEGG: slo:Shew_3612 general secretion pathway protein K YP_001500016.1 TIGRFAM: general secretion pathway protein L; PFAM: General secretion pathway L; KEGG: shm:Shewmr7_0159 general secretion pathway protein L YP_001500017.1 PFAM: General secretion pathway M protein; KEGG: slo:Shew_3610 general secretion pathway M protein YP_001500018.1 PFAM: type II secretion system protein N; KEGG: slo:Shew_3609 type II secretion system protein N YP_001500019.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sbm:Shew185_0160 HAD-superfamily hydrolase, subfamily IA, variant 3 YP_001500020.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001500021.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: slo:Shew_0130 3'(2'),5'-bisphosphate nucleotidase YP_001500022.1 PFAM: GCN5-related N-acetyltransferase; KEGG: slo:Shew_0131 GCN5-related N-acetyltransferase YP_001500023.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfr:Sfri_0122 phospholipid/glycerol acyltransferase YP_001500024.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_001500025.1 catalyzes the formation of selenophosphate from selenide and ATP YP_001500026.1 PFAM: fatty acid desaturase; KEGG: shw:Sputw3181_3679 stearoyl-CoA 9-desaturase YP_001500027.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_001500028.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_001500029.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001500030.1 PFAM: RNP-1 like RNA-binding protein; KEGG: slo:Shew_0140 RNP-1-like RNA-binding protein YP_001500031.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001500032.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001500033.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001500034.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001500035.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001500036.1 TIGRFAM: transcription termination/antitermination factor NusG; PFAM: KOW domain protein; NGN domain protein; KEGG: slo:Shew_0146 NusG antitermination factor YP_001500037.1 binds directly to 23S ribosomal RNA YP_001500038.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001500039.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001500040.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001500041.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001500042.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001500043.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001500044.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001500045.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001500046.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001500047.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001500048.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001500049.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001500050.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001500051.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001500052.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001500053.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001500054.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001500055.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001500056.1 one of the stabilizing components for the large ribosomal subunit YP_001500057.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001500058.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001500059.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001500060.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001500061.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001500062.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001500063.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001500064.1 binds 5S rRNA along with protein L5 and L25 YP_001500065.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001500066.1 TIGRFAM: ribosomal protein L30; KEGG: sfr:Sfri_0166 ribosomal protein L30 YP_001500067.1 late assembly protein YP_001500068.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001500069.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001500070.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001500071.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001500072.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001500073.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001500074.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001500075.1 PFAM: Heme exporter protein D (CcmD); KEGG: shn:Shewana3_0228 heme exporter protein D (CcmD) YP_001500076.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein; KEGG: slo:Shew_0188 heme exporter protein CcmC YP_001500077.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: saz:Sama_0244 heme exporter protein CcmB YP_001500078.1 ATP-binding protein; required for proper cytochrome c maturation YP_001500079.1 PFAM: cytochrome c class I; KEGG: sfr:Sfri_0180 cytochrome c, class I YP_001500080.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: slo:Shew_0192 TPR repeat-containing protein YP_001500081.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: shm:Shewmr7_0229 cytochrome c-type biogenesis protein CcmF YP_001500082.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: son:SO_0267 thiol:disulfide interchange protein DsbE YP_001500083.1 PFAM: cytochrome C biogenesis protein; KEGG: slo:Shew_0195 cytochrome c biogenesis protein YP_001500084.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: slo:Shew_0196 redoxin domain protein YP_001500085.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: sdn:Sden_3445 transposase IS116/IS110/IS902 YP_001500086.1 TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: sbm:Shew185_4098 competence/damage-inducible protein CinA YP_001500087.1 PFAM: protein of unknown function DUF1439; KEGG: slo:Shew_0199 protein of unknown function DUF1439 YP_001500088.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001500089.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_001500090.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001500091.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001500092.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001500093.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001500094.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001500095.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: sbm:Shew185_4090 penicillin-binding protein, 1A family YP_001500096.1 TIGRFAM: type IV pilus assembly protein PilM; KEGG: slo:Shew_0208 type IV pilus assembly protein PilM YP_001500097.1 PFAM: Fimbrial assembly family protein; KEGG: slo:Shew_0209 fimbrial assembly family protein YP_001500098.1 PFAM: Pilus assembly protein PilO; KEGG: sfr:Sfri_0372 pilus assembly protein, PilO YP_001500099.1 PFAM: Pilus assembly protein PilP; KEGG: slo:Shew_0211 pilus assembly protein, PilQ YP_001500100.1 TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; Secretin/TonB short domain; KEGG: slo:Shew_0212 type IV pilus secretin PilQ YP_001500101.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001500102.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001500103.1 PFAM: Sporulation domain protein; KEGG: slo:Shew_0215 sporulation domain protein YP_001500104.1 KEGG: slo:Shew_0216 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_001500105.1 KEGG: sfr:Sfri_0379 hypothetical protein YP_001500106.1 KEGG: slo:Shew_0218 hypothetical protein YP_001500107.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: slo:Shew_0219 ribulose-phosphate 3-epimerase YP_001500108.1 TIGRFAM: phosphoglycolate phosphatase ; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shw:Sputw3181_3841 phosphoglycolate phosphatase YP_001500109.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001500110.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sfr:Sfri_0384 transcriptional regulator, LysR family protein YP_001500111.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sfr:Sfri_0385 protein of unknown function DUF6, transmembrane YP_001500112.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: slo:Shew_0224 transport-associated YP_001500113.1 TIGRFAM: phosphoheptose isomerase; KEGG: shw:Sputw3181_3836 phosphoheptose isomerase YP_001500114.1 PFAM: protein of unknown function UPF0102; KEGG: sbm:Shew185_4070 protein of unknown function UPF0102 YP_001500115.1 PFAM: LppC family lipoprotein; KEGG: slo:Shew_0227 LppC family lipoprotein YP_001500116.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: slo:Shew_0228 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase YP_001500117.1 KEGG: slo:Shew_3355 hypothetical protein YP_001500118.1 KEGG: ppr:PBPRB1788 putative glycine betaine ABC transporter ATP-binding protein; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase YP_001500119.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vha:VIBHAR_06563 hypothetical protein YP_001500120.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: ppr:PBPRB1790 hypothetical ABC transporter, substrate binding protein YP_001500121.1 PFAM: LysR substrate-binding; KEGG: vfi:VFA1061 transcriptional regulators, LysR family YP_001500122.1 KEGG: esa:ESA_03864 hypothetical protein YP_001500123.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gur:Gura_1944 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001500124.1 PFAM: Aldehyde ferredoxin oxidoreductase; KEGG: pth:PTH_0610 aldehyde:ferredoxin oxidoreductase YP_001500127.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: vfi:VF2364 NADH dehydrogenase YP_001500128.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: pin:Ping_2274 sensory transduction histidine kinase YP_001500129.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sfr:Sfri_3440 transcriptional regulator, LysR family protein YP_001500130.1 catalyzes the reaction of formaldehyde with glutathione to form S-hydroxymethylglutathione YP_001500131.1 PFAM: zinc finger DksA/TraR C4-type; KEGG: maq:Maqu_2983 transcriptional regulator, TraR/DksA family YP_001500132.1 TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sfr:Sfri_3427 alcohol dehydrogenase GroES domain protein YP_001500133.1 KEGG: sfr:Sfri_3426 carboxylesterase; TIGRFAM: S-formylglutathione hydrolase; PFAM: putative esterase YP_001500134.1 PFAM: small multidrug resistance protein; KEGG: sfr:Sfri_3425 small multidrug resistance protein YP_001500135.1 KEGG: pin:Ping_1347 hypothetical protein YP_001500136.1 KEGG: pin:Ping_1348 hypothetical protein YP_001500138.1 KEGG: saz:Sama_3582 hypothetical protein YP_001500139.1 KEGG: slo:Shew_0230 hypothetical protein YP_001500140.1 PFAM: protein of unknown function DUF1212; KEGG: slo:Shew_0231 protein of unknown function DUF1212 YP_001500141.1 KEGG: sbl:Sbal_4091 hypothetical protein YP_001500142.1 PFAM: Radical SAM domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: slo:Shew_0233 radical SAM N-terminal domain protein YP_001500143.1 PFAM: protein of unknown function DUF1232; KEGG: slo:Shew_0234 protein of unknown function DUF1232 YP_001500144.1 TIGRFAM: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; PFAM: lipid A biosynthesis acyltransferase; KEGG: vpa:VP1745 lipid A biosynthesis lauroyl acyltransferase YP_001500145.1 KEGG: slo:Shew_0246 hypothetical protein YP_001500146.1 KEGG: slo:Shew_0256 hypothetical protein YP_001500147.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: slo:Shew_0257 peptidase S9, prolyl oligopeptidase active site domain protein YP_001500148.1 KEGG: slo:Shew_0258 hypothetical protein YP_001500149.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: vfi:VFA1016 sensory transduction protein kinase YP_001500150.1 KEGG: ppr:PBPRB1153 hypothetical protein YP_001500151.1 KEGG: ppr:PBPRB1154 hypothetical protein YP_001500153.1 KEGG: esa:ESA_01836 hypothetical protein YP_001500154.1 KEGG: ana:alr3755 unknown protein YP_001500155.1 KEGG: vfi:VFA1013 hypothetical protein YP_001500156.1 KEGG: afm:AFUA_3G10400 dolichol-phosphate mannosyltransferase, putative YP_001500158.1 KEGG: esa:ESA_01830 hypothetical protein YP_001500159.1 KEGG: esa:ESA_01831 hypothetical protein YP_001500160.1 KEGG: ava:Ava_1569 hypothetical protein YP_001500161.1 PFAM: glycosyl transferase family 2; KEGG: esa:ESA_01833 hypothetical protein YP_001500162.1 KEGG: vpa:VPA1048 putative anti-sigma F factor antagonist YP_001500163.1 PFAM: Nucleotidyl transferase; KEGG: ana:alr3400 mannose-1-phosphate guanyltransferase YP_001500164.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: rsh:Rsph17029_0151 anti-sigma-factor antagonist YP_001500165.1 PFAM: response regulator receiver; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: vha:VIBHAR_05599 hypothetical protein YP_001500166.1 KEGG: slo:Shew_0259 hypothetical protein YP_001500167.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: shw:Sputw3181_3091 TonB-dependent receptor YP_001500168.1 PFAM: EAL domain protein; phosphotransferase system EIIC; KEGG: vha:VIBHAR_05166 hypothetical protein YP_001500169.1 KEGG: slo:Shew_0260 hypothetical protein YP_001500170.1 KEGG: slo:Shew_0261 hypothetical protein YP_001500171.1 PFAM: protein of unknown function UPF0061; KEGG: she:Shewmr4_3645 protein of unknown function UPF0061 YP_001500172.1 KEGG: shn:Shewana3_3840 hypothetical protein YP_001500173.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_001500174.1 PFAM: DSBA oxidoreductase; KEGG: slo:Shew_0265 DsbA oxidoreductase YP_001500175.1 PFAM: protein of unknown function DUF1107; KEGG: shw:Sputw3181_3796 protein of unknown function DUF1107 YP_001500176.1 PFAM: protein of unknown function DUF904; KEGG: slo:Shew_0267 protein of unknown function DUF904 YP_001500177.1 PFAM: Citrate transporter; Na+/H+ antiporter NhaC; KEGG: sbm:Shew185_4032 Na+ antiporter NhaC YP_001500178.1 KEGG: slo:Shew_0270 hypothetical protein YP_001500179.1 KEGG: slo:Shew_0271 phospholipase YP_001500180.1 KEGG: vvy:VVA0223 hypothetical protein YP_001500181.1 PFAM: alpha/beta hydrolase fold; KEGG: ppr:PBPRB0984 hypothetical protein YP_001500182.1 KEGG: vpa:VP1355 hypothetical protein YP_001500183.1 KEGG: vpa:VP1356 hypothetical protein YP_001500184.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: slo:Shew_0272 cupin 2, conserved barrel domain protein YP_001500185.1 KEGG: son:SO_1411 hypothetical protein YP_001500186.1 KEGG: slo:Shew_0274 hypothetical protein YP_001500187.1 KEGG: slo:Shew_0275 tetraheme cytochrome c, putative YP_001500188.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: slo:Shew_0276 flavocytochrome c YP_001500189.1 PFAM: regulatory protein TetR; KEGG: sbm:Shew185_2533 transcriptional regulator, TetR family YP_001500190.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001500192.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: she:Shewmr4_3626 phospholipid/glycerol acyltransferase YP_001500193.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: slo:Shew_0282 phospholipid/glycerol acyltransferase YP_001500194.1 PFAM: EAL domain protein; KEGG: swi:Swit_2925 EAL domain protein YP_001500195.1 KEGG: sbl:Sbal_4042 Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001500196.1 PFAM: KAP P-loop domain protein; KEGG: sdn:Sden_3526 kap P-loop YP_001500197.1 PFAM: histidine kinase A domain protein; KEGG: vha:VIBHAR_05571 hypothetical protein YP_001500198.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: vha:VIBHAR_05570 hypothetical protein YP_001500199.1 KEGG: vha:VIBHAR_05569 hypothetical protein YP_001500200.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; KEGG: vpa:VPA0596 putative methyl-accepting chemotaxis protein YP_001500201.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: son:SO_3299 Pal/histidase family protein YP_001500202.1 KEGG: son:SO_3300 cytochrome c YP_001500203.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO_3301 flavocytochrome c flavin subunit YP_001500204.1 PFAM: regulatory protein LysR; KEGG: son:SO_3297 transcriptional regulator, LysR family YP_001500205.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: shw:Sputw3181_0406 transcriptional regulator, LysR family YP_001500206.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_001500207.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001500208.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_001500209.1 KEGG: shw:Sputw3181_3753 amino acid-binding ACT domain protein YP_001500210.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001500211.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001500212.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_001500213.1 PFAM: aminotransferase class V; KEGG: son:SO_4343 aminotransferase, class V YP_001500214.1 TIGRFAM: TonB-dependent copper receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sdn:Sden_0470 TonB-dependent copper receptor YP_001500215.1 PFAM: sodium:neurotransmitter symporter; KEGG: slo:Shew_0300 sodium:neurotransmitter symporter YP_001500216.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: slo:Shew_0301 transcriptional regulator, AsnC family YP_001500217.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: shn:Shewana3_0364 phosphoesterase, PA-phosphatase related YP_001500218.1 PFAM: protein of unknown function DUF417; KEGG: mmr:Mmar10_2310 protein of unknown function DUF417 YP_001500219.1 PFAM: protein of unknown function DUF526; KEGG: slo:Shew_0304 protein of unknown function DUF526 YP_001500220.1 PFAM: acriflavin resistance protein; KEGG: shn:Shewana3_0371 acriflavin resistance protein YP_001500221.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shn:Shewana3_0372 efflux transporter, RND family, MFP subunit YP_001500222.1 PFAM: regulatory protein TetR; KEGG: son:SO_4326 transcriptional regulator, TetR family YP_001500223.1 TIGRFAM: ATP-dependent DNA helicase Rep; PFAM: UvrD/REP helicase; KEGG: sbm:Shew185_3990 ATP-dependent DNA helicase Rep YP_001500224.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: slo:Shew_0306 diguanylate cyclase/phosphodiesterase with GAF sensor YP_001500225.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase HAMP region domain protein; KEGG: slo:Shew_0307 diguanylate cyclase/phosphodiesterase YP_001500226.1 KEGG: slo:Shew_0308 hypothetical protein YP_001500227.1 PFAM: OmpA/MotB domain protein; KEGG: slo:Shew_0309 OmpA/MotB domain protein YP_001500228.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: slo:Shew_0310 type I secretion outer membrane protein, TolC family YP_001500229.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_0311 type I secretion membrane fusion protein, HlyD family YP_001500230.1 PFAM: ABC transporter related; peptidase C39 bacteriocin processing; SMART: AAA ATPase; KEGG: slo:Shew_0312 ABC transporter-related protein YP_001500231.1 PFAM: Hemolysin-type calcium-binding region; von Willebrand factor type A; Cadherin; Na-Ca exchanger/integrin-beta4; KEGG: eca:ECA3266 putative hemagglutinin/hemolysin-related protein YP_001500232.1 TIGRFAM: putative outer membrane adhesin like proteiin; PFAM: Hemolysin-type calcium-binding region; KEGG: slo:Shew_0314 putative outer membrane adhesin like proteiin YP_001500233.1 PFAM: HemY domain protein; KEGG: slo:Shew_0315 HemY domain protein YP_001500234.1 PFAM: protein of unknown function DUF513 hemX; KEGG: slo:Shew_0316 protein of unknown function DUF513, HemX YP_001500235.1 PFAM: Uroporphyrinogen III synthase HEM4; KEGG: shw:Sputw3181_3727 uroporphyrinogen III synthase HEM4 YP_001500236.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001500237.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_001500238.1 PFAM: Frataxin family protein; KEGG: sbm:Shew185_3976 frataxin family protein YP_001500239.1 KEGG: sbl:Sbal_3997 hypothetical protein YP_001500240.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: slo:Shew_0322 diaminopimelate decarboxylase YP_001500241.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001500242.1 PFAM: protein of unknown function DUF484; KEGG: slo:Shew_0324 protein of unknown function DUF484 YP_001500243.1 TIGRFAM: tyrosine recombinase XerC; PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: sbl:Sbal_3993 tyrosine recombinase XerC YP_001500244.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: she:Shewmr4_0395 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_001500245.1 PFAM: Egg lysin (Sperm-lysin); KEGG: saz:Sama_3237 lipoprotein, putative YP_001500246.1 PFAM: protein of unknown function DUF542 ScdA domain protein; Hemerythrin HHE cation binding domain protein; KEGG: sbm:Shew185_3967 hemerythrin HHE cation binding domain protein YP_001500248.1 PFAM: outer membrane efflux protein; KEGG: cps:CPS_1957 putative RND efflux system protein YP_001500249.1 KEGG: cps:CPS_1958 putative RND efflux system protein, MFP subunit YP_001500250.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: cps:CPS_1959 putative RND efflux system protein YP_001500251.1 PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: shm:Shewmr7_3221 leucyl aminopeptidase YP_001500252.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_001500253.1 TIGRFAM: putative TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase DuS; KEGG: slo:Shew_0330 putative TIM-barrel protein, nifR3 family YP_001500254.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001500255.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit YP_001500256.1 PFAM: fumarate reductase respiratory complex transmembrane subunit; KEGG: sbl:Sbal_3936 fumarate reductase respiratory complex, transmembrane subunit YP_001500257.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001500258.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001500259.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_0336 transcriptional regulator, LysR family YP_001500260.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001500261.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: son:SO_0406 thioredoxin 1 YP_001500262.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_001500263.1 PFAM: Ppx/GppA phosphatase; KEGG: slo:Shew_0340 Ppx/GppA phosphatase YP_001500264.1 PFAM: TonB-dependent receptor; Cna B domain protein; TonB-dependent receptor plug; KEGG: saz:Sama_3213 putative oar protein YP_001500265.1 KEGG: mmw:Mmwyl1_3491 transposase YP_001500266.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3340 integrase, catalytic region YP_001500267.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: slo:Shew_0341 TonB-dependent receptor YP_001500268.1 KEGG: slo:Shew_0342 hypothetical protein YP_001500269.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: sdn:Sden_3445 transposase IS116/IS110/IS902 YP_001500270.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: slo:Shew_3444 mutator MutT protein YP_001500271.1 PFAM: protein of unknown function DUF329; KEGG: slo:Shew_3443 protein of unknown function DUF329 YP_001500272.1 PFAM: protein of unknown function DUF1342; KEGG: slo:Shew_3442 protein of unknown function DUF1342 YP_001500273.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001500274.1 PFAM: peptidase A24A prepilin type IV; peptidase A24A domain protein; KEGG: sbm:Shew185_3944 prepilin peptidase YP_001500275.1 PFAM: type II secretion system protein; KEGG: shn:Shewana3_0418 type II secretion system protein YP_001500276.1 TIGRFAM: type IV-A pilus assembly ATPase PilB; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; KEGG: slo:Shew_3438 type IV-A pilus assembly ATPase PilB YP_001500277.1 KEGG: sbl:Sbal_3918 methylation site containing protein YP_001500278.1 KEGG: shn:Shewana3_0422 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase YP_001500279.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: slo:Shew_3434 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD YP_001500280.1 involved in regulation of beta-lactamase; putative signaling protein YP_001500281.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_001500282.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001500283.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains YP_001500284.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001500285.1 KEGG: slo:Shew_3428 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001500286.1 PFAM: Patatin; surface antigen variable number repeat protein; KEGG: sbl:Sbal_3909 patatin YP_001500287.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_001500288.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001500289.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_001500290.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001500291.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-4 domain protein; PAS fold domain protein; KEGG: shn:Shewana3_0436 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) YP_001500292.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: shm:Shewmr7_3588 short-chain dehydrogenase/reductase SDR YP_001500293.1 KEGG: shn:Shewana3_0438 hypothetical protein YP_001500294.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001500295.1 involved in de novo purine biosynthesis YP_001500296.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_001500297.1 PFAM: permease; KEGG: slo:Shew_3410 permease YP_001500298.1 PFAM: DSBA oxidoreductase; KEGG: maq:Maqu_3568 DsbA oxidoreductase YP_001500299.1 PFAM: putative thiol-disulphide oxidoreductase DCC; KEGG: gfo:GFO_1625 protein containing DUF393 YP_001500300.1 PFAM: molybdopterin oxidoreductase Fe4S4 region; KEGG: sbm:Shew185_0099 molybdopterin oxidoreductase Fe4s4 region YP_001500301.1 KEGG: sbm:Shew185_0099 molybdopterin oxidoreductase Fe4s4 region; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_001500302.1 TIGRFAM: formate dehydrogenase, beta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Formate dehydrogenase transmembrane domain protein; KEGG: sbm:Shew185_0101 formate dehydrogenase, beta subunit YP_001500303.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: she:Shewmr4_0104 formate dehydrogenase, gamma subunit YP_001500304.1 TIGRFAM: formate dehydrogenase accessory protein FdhE; PFAM: formate dehydrogenase accessory protein; KEGG: son:SO_0104 fdhE protein YP_001500305.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_001500306.1 TIGRFAM: selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; Elongation factor SelB winged helix 2; Elongation factor SelB winged helix 3; KEGG: shn:Shewana3_0107 selenocysteine-specific translation elongation factor YP_001500307.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_001500308.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: shn:Shewana3_0109 protein of unknown function DUF395, YeeE/YedE YP_001500309.1 PFAM: SirA family protein; KEGG: cko:CKO_01008 hypothetical protein YP_001500310.1 PFAM: protein of unknown function DUF28; KEGG: sbm:Shew185_1289 protein of unknown function DUF28 YP_001500311.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: vha:VIBHAR_01722 hypothetical protein YP_001500312.1 KEGG: vha:VIBHAR_05268 hypothetical protein YP_001500313.1 KEGG: slo:Shew_2580 hypothetical protein YP_001500314.1 PFAM: GCN5-related N-acetyltransferase; KEGG: slo:Shew_3397 GCN5-related N-acetyltransferase YP_001500315.1 KEGG: slo:Shew_3396 hypothetical protein YP_001500316.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: shm:Shewmr7_3501 radical SAM domain protein YP_001500317.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rso:RSc0144 probable transcription regulator protein YP_001500318.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ppu:PP_3608 transcriptional regulator, LysR family YP_001500319.1 PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: slo:Shew_1090 OmpA/MotB domain protein YP_001500320.1 PFAM: MscS Mechanosensitive ion channel; KEGG: slo:Shew_3394 MscS mechanosensitive ion channel YP_001500321.1 KEGG: shw:Sputw3181_3632 hypothetical protein YP_001500322.1 KEGG: sbm:Shew185_0466 protein of unknown function DUF465 YP_001500323.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_001500324.1 KEGG: slo:Shew_3389 hypothetical protein YP_001500325.1 PFAM: protein of unknown function DUF107; KEGG: shm:Shewmr7_0449 protein of unknown function DUF107 YP_001500326.1 PFAM: band 7 protein; KEGG: slo:Shew_3387 band 7 protein YP_001500327.1 PFAM: band 7 protein; KEGG: slo:Shew_3386 band 7 protein YP_001500328.1 PFAM: NUDIX hydrolase; KEGG: shn:Shewana3_0463 NUDIX hydrolase YP_001500329.1 KEGG: cps:CPS_1933 sensory box/GGDEF/EAL domain protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; SMART: PAS domain containing protein YP_001500330.1 PFAM: Endoribonuclease L-PSP; KEGG: cps:CPS_4240 endoribonuclease, L-PSP family YP_001500331.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_001500332.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_001500333.1 KEGG: slo:Shew_3383 hypothetical protein YP_001500334.1 PFAM: putative esterase; KEGG: sfr:Sfri_3395 hydrolase of the alpha/beta superfamily YP_001500335.1 KEGG: sfr:Sfri_3394 hypothetical protein YP_001500336.1 KEGG: slo:Shew_0343 hypothetical protein YP_001500338.1 PFAM: Na+/H+ antiporter NhaC; KEGG: slo:Shew_0344 Na+/H+ antiporter NhaC YP_001500339.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: slo:Shew_0345 redoxin domain protein YP_001500340.1 PFAM: cytochrome C biogenesis protein; KEGG: shw:Sputw3181_0575 cytochrome c biogenesis protein YP_001500341.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: son:SO_0478 cytochrome c-type biogenesis protein CcmF YP_001500342.1 KEGG: slo:Shew_0348 cytochrome c, putative YP_001500343.1 SMART: Rhodanese domain protein; KEGG: shw:Sputw3181_0578 rhodanese domain protein YP_001500344.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase FKBP-type; KEGG: slo:Shew_0350 peptidylprolyl isomerase, FKBP-type YP_001500345.1 KEGG: son:SO_0482 formate-dependent nitrite reductase, NrfG protein YP_001500346.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: she:Shewmr4_0492 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001500347.1 PFAM: Polysulphide reductase NrfD; KEGG: slo:Shew_0353 polysulphide reductase, NrfD YP_001500348.1 PFAM: NosL family protein; KEGG: shm:Shewmr7_3536 NosL family protein YP_001500349.1 PFAM: periplasmic copper-binding; SMART: Parallel beta-helix repeat; Carbohydrate-binding and sugar hydrolysis; KEGG: shw:Sputw3181_0582 periplasmic copper-binding YP_001500350.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_0356 ABC transporter-related protein YP_001500351.1 KEGG: slo:Shew_0357 copper ABC transporter, permease protein YP_001500352.1 PFAM: transcriptional regulator domain protein; KEGG: shm:Shewmr7_3532 transcriptional regulator, CadC YP_001500354.1 KEGG: ppr:PBPRC0048 hypothetical protein YP_001500355.1 KEGG: sdn:Sden_3087 protein of unknown function DUF1568 YP_001500356.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: cps:CPS_3142 transporter, LysE family YP_001500357.1 KEGG: sdn:Sden_1610 protein of unknown function DUF1568 YP_001500358.1 KEGG: son:SO_1241 hypothetical protein YP_001500359.1 KEGG: vfi:VFA0138 hypothetical protein YP_001500360.1 PFAM: FNIP; KEGG: tva:TVAG_154640 surface antigen BspA-like Pfam: FNIP Pentapeptide_2 PROSITE: SER_RICH YP_001500362.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: bcz:pE33L466_0259 possible drug/metabolite exporter YP_001500363.1 PFAM: ferredoxin; KEGG: ppr:PBPRB0250 hypothetical protein YP_001500364.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001500365.1 PFAM: Glutathione S-transferase domain; KEGG: ppr:PBPRB0252 putative glutathione S-transferase YP_001500366.1 KEGG: slo:Shew_0348 cytochrome c, putative YP_001500367.1 SMART: Rhodanese domain protein; KEGG: slo:Shew_0349 rhodanese domain protein YP_001500368.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase FKBP-type; KEGG: slo:Shew_0350 peptidylprolyl isomerase, FKBP-type YP_001500369.1 KEGG: slo:Shew_0351 tetratricopeptide TPR_2 repeat protein YP_001500370.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: she:Shewmr4_0492 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001500371.1 PFAM: Polysulphide reductase NrfD; KEGG: slo:Shew_0353 polysulphide reductase, NrfD YP_001500372.1 PFAM: NosL family protein; KEGG: sbm:Shew185_3871 NosL family protein YP_001500373.1 PFAM: periplasmic copper-binding; SMART: Parallel beta-helix repeat; Carbohydrate-binding and sugar hydrolysis; KEGG: shw:Sputw3181_0582 periplasmic copper-binding YP_001500374.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_0356 ABC transporter-related protein YP_001500375.1 PFAM: ABC-2 type transporter; KEGG: slo:Shew_0357 copper ABC transporter, permease protein YP_001500376.1 PFAM: transcriptional regulator domain protein; KEGG: shn:Shewana3_0499 transcriptional regulator, CadC YP_001500377.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_001500378.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_001500379.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_001500380.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system YP_001500381.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_001500382.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: vco:VC0395_0006 ribose operon repressor YP_001500383.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_001500384.1 TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; KEGG: slo:Shew_0360 UbiD family decarboxylase YP_001500385.1 KEGG: sfr:Sfri_3388 hypothetical protein YP_001500386.1 KEGG: saz:Sama_3100 hypothetical protein YP_001500387.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sfr:Sfri_3606 GCN5-related N-acetyltransferase YP_001500388.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cps:CPS_2140 putative lipoprotein YP_001500389.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: ppr:PBPRA2465 putative tyrosine-specific transport protein YP_001500390.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_001500391.1 KEGG: gur:Gura_0621 hypothetical protein YP_001500392.1 KEGG: spc:Sputcn32_0051 putative plasmid transfer protein YP_001500393.1 KEGG: sfr:Sfri_3568 hypothetical protein YP_001500395.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sbl:Sbal_0468 short-chain dehydrogenase/reductase SDR YP_001500396.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: vfi:VF2386 biotin carboxyl carrier protein of acetyl-CoA carboxylase YP_001500397.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001500398.1 PFAM: Class I peptide chain release factor; KEGG: sbm:Shew185_3853 class I peptide chain release factor YP_001500399.1 KEGG: sdn:Sden_3283 hypothetical protein YP_001500400.1 KEGG: sbl:Sbal_0473 hypothetical protein YP_001500401.1 KEGG: slo:Shew_3359 hypothetical protein YP_001500402.1 KEGG: slo:Shew_3358 outer membrane efflux family protein, putative YP_001500403.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: slo:Shew_3357 efflux transporter, RND family, MFP subunit YP_001500404.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: slo:Shew_3356 heavy metal efflux pump, CzcA family YP_001500405.1 KEGG: spc:Sputcn32_0183 hypothetical protein YP_001500406.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_001500407.1 PFAM: aminotransferase class V; beta-lactamase domain protein; Rhodanese domain protein; KEGG: slo:Shew_3354 aminotransferase, class V YP_001500408.1 PFAM: protein of unknown function DUF442; KEGG: sfr:Sfri_3576 hypothetical protein YP_001500409.1 PFAM: conserved hypothetical protein; KEGG: sfr:Sfri_3560 conserved hypothetical protein 22 YP_001500410.1 KEGG: slo:Shew_3350 hypothetical protein YP_001500411.1 KEGG: slo:Shew_3349 ATP-dependent protease La (LON) domain protein, putative YP_001500412.1 PFAM: pseudouridine synthase; KEGG: sbm:Shew185_0433 pseudouridine synthase YP_001500413.1 KEGG: shn:Shewana3_3710 hypothetical protein YP_001500414.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: shn:Shewana3_3709 dTDP-4-dehydrorhamnose reductase YP_001500415.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: slo:Shew_3343 integral membrane sensor signal transduction histidine kinase YP_001500416.1 PFAM: response regulator receiver; helix-turn-helix Fis-type; KEGG: sfr:Sfri_1844 response regulator receiver protein YP_001500417.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: slo:Shew_0508 xanthine/uracil/vitamin C permease YP_001500418.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: son:SO_4141 oxidoreductase, short-chain dehydrogenase/reductase family YP_001500419.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: cps:CPS_4936 substrate-binding transcriptional regulator, LysR family YP_001500420.1 KEGG: slo:Shew_0517 putative plasmid transfer protein YP_001500421.1 PFAM: protein of unknown function DUF81; KEGG: shw:Sputw3181_3556 protein of unknown function DUF81 YP_001500422.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_001500423.1 KEGG: she:Shewmr4_3439 O-succinylhomoserine (thiol)-lyase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein YP_001500424.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001500425.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_001500426.1 KEGG: slo:Shew_0526 hypothetical protein YP_001500427.1 KEGG: shn:Shewana3_3604 hypothetical protein YP_001500428.1 PFAM: protein of unknown function DUF6 transmembrane; UAA transporter; KEGG: she:Shewmr4_3427 protein of unknown function DUF6, transmembrane YP_001500429.1 PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: slo:Shew_0531 DEAD/DEAH box helicase domain protein YP_001500430.1 PFAM: peptidase M20; peptidase M28; KEGG: slo:Shew_0532 peptidase M28 YP_001500431.1 KEGG: shm:Shewmr7_0530 hypothetical protein YP_001500432.1 TIGRFAM: excinuclease ABC, A subunit; PFAM: ABC transporter related; KEGG: shw:Sputw3181_3536 excinuclease ABC, A subunit YP_001500433.1 PFAM: major facilitator superfamily MFS_1; KEGG: slo:Shew_0534 major facilitator superfamily MFS_1 YP_001500434.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: shw:Sputw3181_3534 single-strand binding protein YP_001500435.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3562 integrase, catalytic region YP_001500436.1 KEGG: sfr:Sfri_3563 transposase YP_001500437.1 KEGG: sdn:Sden_0410 putative cation efflux protein YP_001500438.1 KEGG: slo:Shew_3273 hypothetical protein YP_001500439.1 PFAM: Aldose 1-epimerase; KEGG: sdn:Sden_0413 aldose 1-epimerase YP_001500440.1 TIGRFAM: galactokinase; PFAM: GHMP kinase; GHMP kinase domain protein; KEGG: slo:Shew_3271 galactokinase YP_001500441.1 TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: slo:Shew_3270 SSS sodium solute transporter superfamily YP_001500442.1 KEGG: slo:Shew_3269 beta-galactosidase YP_001500443.1 PFAM: glycoside hydrolase family 42 domain 5 loop region; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: slo:Shew_3269 beta-galactosidase YP_001500444.1 PFAM: WD40 domain protein beta Propeller; KEGG: slo:Shew_3268 hypothetical protein YP_001500445.1 PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: slo:Shew_3267 sodium/hydrogen exchanger YP_001500446.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_001500447.1 PFAM: CutA1 divalent ion tolerance protein; KEGG: sbl:Sbal_3725 CutA1 divalent ion tolerance protein YP_001500448.1 PFAM: FxsA cytoplasmic membrane protein; KEGG: slo:Shew_3264 FxsA cytoplasmic membrane protein YP_001500449.1 SMART: serine/threonine protein kinase; KEGG: slo:Shew_3263 serine/threonine protein kinase YP_001500450.1 KEGG: slo:Shew_3262 hypothetical protein YP_001500451.1 catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide YP_001500452.1 PFAM: porin Gram-negative type; KEGG: sfr:Sfri_0503 porin, gram-negative type YP_001500453.1 PFAM: porin Gram-negative type; KEGG: slo:Shew_3252 porin, gram-negative type YP_001500454.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: slo:Shew_3251 UBA/ThiF-type NAD/FAD binding protein YP_001500455.1 KEGG: slo:Shew_3248 hypothetical protein YP_001500456.1 KEGG: saz:Sama_0549 hypothetical protein YP_001500457.1 PFAM: peptidase S15; peptidase S9 prolyl oligopeptidase active site domain protein; dienelactone hydrolase; KEGG: son:SO_A0048 prolyl oligopeptidase family protein YP_001500458.1 PFAM: peptidase M50; KEGG: slo:Shew_3232 peptidase M50 YP_001500459.1 PFAM: protein of unknown function DUF342; KEGG: slo:Shew_3231 protein of unknown function DUF342 YP_001500460.1 PFAM: methyltransferase small; Methyltransferase type 12; Methyltransferase small domain protein; KEGG: she:Shewmr4_0687 rRNA (guanine-N(2)-)-methyltransferase YP_001500461.1 PFAM: Alkaline phosphatase; KEGG: slo:Shew_3226 alkaline phosphatase YP_001500462.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001500463.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001500464.1 PFAM: Endonuclease I; KEGG: ppr:PBPRC0029 putative endonuclease I YP_001500465.1 PFAM: protein of unknown function DUF335 SprT; SMART: protein of unknown function SprT; KEGG: slo:Shew_3222 protein of unknown function DUF335, SprT YP_001500466.1 KEGG: slo:Shew_3221 hypothetical protein YP_001500467.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_3219 transcriptional regulator, LysR family YP_001500468.1 PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: slo:Shew_3218 carbamoyl-phosphate synthase L chain, ATP-binding YP_001500469.1 PFAM: sodium/hydrogen exchanger; KEGG: noc:Noc_0960 sodium/hydrogen exchanger YP_001500470.1 KEGG: spc:Sputcn32_3895 hypothetical protein YP_001500471.1 KEGG: spc:Sputcn32_3894 UDP-galactopyranose mutase; TIGRFAM: UDP-galactopyranose mutase; PFAM: UDP-galactopyranose mutase-like YP_001500472.1 PFAM: Sporulation domain protein; KEGG: pha:PSHAa0751 hypothetical protein YP_001500475.1 KEGG: pol:Bpro_5311 hypothetical protein YP_001500476.1 KEGG: pol:Bpro_5310 hypothetical protein YP_001500477.1 PFAM: Sporulation domain protein; KEGG: pha:PSHAa0753 hypothetical protein YP_001500478.1 KEGG: sdn:Sden_0845 hypothetical protein YP_001500479.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: psa:PST_2459 transcriptional regulator, AraC family YP_001500480.1 KEGG: sma:SAV5462 hypothetical protein YP_001500481.1 KEGG: sfr:Sfri_2734 hypothetical protein YP_001500483.1 PFAM: Nitrate reductase cytochrome c-type subunit (NapB); KEGG: slo:Shew_3209 nitrate reductase cytochrome c-type subunit (NapB) YP_001500484.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA YP_001500485.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway YP_001500486.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001500487.1 PFAM: NapD family protein; KEGG: slo:Shew_3205 NapD family protein YP_001500488.1 KEGG: slo:Shew_3203 hypothetical protein YP_001500489.1 PFAM: protein of unknown function DUF214; KEGG: sbm:Shew185_0832 protein of unknown function DUF214 YP_001500490.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO_0857 ABC transporter, ATP-binding protein YP_001500491.1 KEGG: slo:Shew_3200 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001500492.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: slo:Shew_3199 response regulator receiver modulated metal dependent phosphohydrolase YP_001500493.1 PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: slo:Shew_3198 glycine cleavage T protein (aminomethyl transferase) YP_001500494.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001500495.1 KEGG: slo:Shew_3195 hypothetical protein YP_001500496.1 PFAM: regulatory protein LuxR; KEGG: saz:Sama_2948 response regulator receiver protein YP_001500497.1 PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: vfi:VFA0967 nucleoside permease NupC YP_001500498.1 TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: aha:AHA_3687 purine nucleoside phosphorylase YP_001500499.1 PFAM: thioesterase superfamily protein; KEGG: slo:Shew_3192 uncharacterized domain 1 protein YP_001500500.1 KEGG: sdn:Sden_3091 hypothetical protein YP_001500501.1 PFAM: Catalase domain protein; KEGG: slo:Shew_3190 catalase YP_001500502.1 PFAM: protein of unknown function UPF0016; KEGG: son:SO_1071 hypothetical protein YP_001500503.1 PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: slo:Shew_3188 aromatic amino acid permease YP_001500504.1 KEGG: slo:Shew_3187 hypothetical protein YP_001500507.1 TIGRFAM: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; PFAM: lipid A biosynthesis acyltransferase; KEGG: slo:Shew_0658 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase YP_001500508.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_001500509.1 KEGG: shm:Shewmr7_0887 hypothetical protein YP_001500510.1 PFAM: regulatory protein TetR; KEGG: saz:Sama_0733 putative transcriptional regulator, TetR family YP_001500511.1 PFAM: MltA-interacting MipA family protein; KEGG: vfi:VF1562 hypothetical protein YP_001500512.1 PFAM: NAD(P) transhydrogenase beta subunit; KEGG: slo:Shew_0662 NAD(P) transhydrogenase, beta subunit YP_001500513.1 KEGG: slo:Shew_0663 oxidoreductase YP_001500514.1 PFAM: alanine dehydrogenase/PNT domain protein; KEGG: slo:Shew_0664 alanine dehydrogenase/PNT domain protein YP_001500515.1 TIGRFAM: sulfite reductase [NADPH] flavoprotein, alpha chain; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; flavodoxin/nitric oxide synthase; KEGG: sfr:Sfri_3193 sulfite reductase (NADPH) flavoprotein, alpha chain YP_001500516.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_001500517.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_001500518.1 KEGG: slo:Shew_0668 hypothetical protein YP_001500519.1 KEGG: pfl:PFL_5750 hypothetical protein YP_001500520.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: slo:Shew_0669 redoxin domain protein YP_001500521.1 PFAM: protein of unknown function RIO1; KEGG: shm:Shewmr7_3358 protein of unknown function RIO1 YP_001500522.1 KEGG: shw:Sputw3181_0899 peptidase S41 YP_001500523.1 PFAM: phospholipase A1; KEGG: saz:Sama_2893 phospholipase A(1) YP_001500524.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sbm:Shew185_0927 uroporphyrin-III C-methyltransferase YP_001500525.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001500526.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_001500527.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: she:Shewmr4_3070 TrkA-C domain protein YP_001500528.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_001500529.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_2239 GCN5-related N-acetyltransferase YP_001500530.1 KEGG: sbl:Sbal_3402 hypothetical protein YP_001500531.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbm:Shew185_0935 major facilitator superfamily MFS_1 YP_001500532.1 KEGG: sbm:Shew185_0936 hypothetical protein YP_001500533.1 KEGG: slo:Shew_0676 putative lipoprotein YP_001500534.1 PFAM: protein of unknown function DUF1111; KEGG: sfr:Sfri_0812 protein of unknown function DUF1111 YP_001500535.1 KEGG: slo:Shew_0678 protoporphyrinogen oxidase YP_001500536.1 KEGG: slo:Shew_0679 hypothetical protein YP_001500537.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: slo:Shew_3180 pseudouridine synthase YP_001500538.1 KEGG: slo:Shew_3179 hypothetical protein YP_001500539.1 PFAM: Na+/H+ antiporter NhaC; KEGG: slo:Shew_3178 Na+/H+ antiporter NhaC YP_001500540.1 KEGG: ppr:PBPRB1186 hypothetical protein YP_001500541.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Tetratricopeptide TPR_2 repeat protein; KEGG: sfr:Sfri_1337 diguanylate cyclase YP_001500542.1 PFAM: porin Gram-negative type; KEGG: slo:Shew_2481 porin, gram-negative type YP_001500543.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3562 integrase, catalytic region YP_001500544.1 KEGG: sfr:Sfri_3563 transposase YP_001500545.1 PFAM: protein of unknown function DUF541; KEGG: shn:Shewana3_3626 protein of unknown function DUF541 YP_001500546.1 KEGG: ter:Tery_4461 cob(II)yrinic acid a,c-diamide reductase; TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase YP_001500547.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_001500548.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: slo:Shew_3144 UDP-N-acetylmuramate YP_001500549.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; KEGG: shn:Shewana3_0792 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001500550.1 KEGG: slo:Shew_3142 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_001500551.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_3141 ABC transporter-related protein YP_001500552.1 PFAM: ABC-2 type transporter; KEGG: slo:Shew_3140 ABC-2 type transporter YP_001500553.1 KEGG: slo:Shew_3139 hypothetical protein YP_001500554.1 KEGG: shm:Shewmr7_3298 hypothetical protein YP_001500555.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001500556.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001500557.1 KEGG: shm:Shewmr7_3295 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK YP_001500558.1 KEGG: slo:Shew_3131 poly(A) polymerase; TIGRFAM: poly(A) polymerase; PFAM: Polynucleotide adenylyltransferase region YP_001500559.1 PFAM: glutamyl-tRNA synthetase class Ic; KEGG: sbm:Shew185_0848 glutamate--tRNA ligase YP_001500560.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: sbm:Shew185_0849 transcriptional regulator, TraR/DksA family YP_001500561.1 Regulatory factor involved in maltose metabolism YP_001500562.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_001500563.1 PFAM: transcriptional regulator domain protein; KEGG: shn:Shewana3_0468 putative transcriptional regulator, CadC YP_001500564.1 KEGG: pin:Ping_1759 hypothetical protein YP_001500565.1 TIGRFAM: 2'-5' RNA ligase; PFAM: Phosphoesterase HXTX; KEGG: pin:Ping_1760 2'-5' RNA ligase YP_001500566.1 KEGG: sbl:Sbal_0582 ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; Helicase ATP-dependent domain protein; SMART: DEAD-like helicases YP_001500567.1 KEGG: slo:Shew_3123 penicillin-binding protein 1B; TIGRFAM: penicillin-binding protein 1B; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase YP_001500568.1 KEGG: sdn:Sden_0673 hypothetical protein YP_001500569.1 PFAM: major facilitator superfamily MFS_1; KEGG: ent:Ent638_2000 major facilitator superfamily MFS_1 YP_001500570.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdn:Sden_1378 GCN5-related N-acetyltransferase YP_001500571.1 PFAM: PepSY-associated TM helix domain protein; KEGG: slo:Shew_3122 PepSY-associated TM helix domain protein YP_001500573.1 PFAM: FMN-binding domain protein; KEGG: sbl:Sbal_2015 FMN-binding domain protein YP_001500574.1 PFAM: phosphate-selective porin O and P; KEGG: slo:Shew_3120 phosphate-selective porin O and P YP_001500575.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: shm:Shewmr7_3399 TonB-dependent receptor YP_001500576.1 KEGG: shn:Shewana3_0631 hypothetical protein YP_001500577.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: slo:Shew_0496 amino acid carrier protein YP_001500578.1 KEGG: slo:Shew_3118 hypothetical protein YP_001500579.1 KEGG: slo:Shew_3117 hypothetical protein YP_001500580.1 KEGG: shm:Shewmr7_3380 hypothetical protein YP_001500581.1 PFAM: sodium:dicarboxylate symporter; KEGG: shw:Sputw3181_3503 sodium:dicarboxylate symporter YP_001500582.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: sfr:Sfri_3688 two component, sigma54 specific, transcriptional regulator, fis family protein YP_001500583.1 PFAM: ATP-binding region ATPase domain protein; SMART: extracellular solute-binding protein family 3; KEGG: slo:Shew_3113 histidine kinase YP_001500584.1 KEGG: slo:Shew_3112 flavocytochrome c; TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001500585.1 PFAM: alpha/beta hydrolase fold; KEGG: bld:BLi02552 YqjL YP_001500586.1 KEGG: sdn:Sden_2209 hypothetical protein YP_001500587.1 PFAM: basic membrane lipoprotein; KEGG: pin:Ping_1297 basic membrane lipoprotein YP_001500588.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pin:Ping_1298 ABC transporter ATP-binding protein YP_001500589.1 PFAM: inner-membrane translocator; KEGG: pin:Ping_1299 ABC transporter inner-membrane translocator YP_001500590.1 PFAM: inner-membrane translocator; KEGG: pin:Ping_1300 ABC sugar transporter inner membrane translocator YP_001500592.1 KEGG: pol:Bpro_1213 hypothetical protein YP_001500593.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001500594.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9B dipeptidylpeptidase IV domain protein; KEGG: slo:Shew_0774 peptidase S9B, dipeptidylpeptidase IV domain protein YP_001500595.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: slo:Shew_0777 two component transcriptional regulator, winged helix family YP_001500596.1 KEGG: slo:Shew_0778 hypothetical protein YP_001500597.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_001500598.1 PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: shn:Shewana3_0653 succinylglutamate desuccinylase/aspartoacylase YP_001500599.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_001500600.1 PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_0827 pseudouridylate synthase YP_001500601.1 KEGG: sfr:Sfri_0516 hypothetical protein YP_001500602.1 PFAM: Tellurite resistance protein TehB; Methyltransferase type 11; Methyltransferase type 12; KEGG: shn:Shewana3_3316 methyltransferase type 12 YP_001500603.1 KEGG: slo:Shew_0786 hypothetical protein YP_001500604.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: slo:Shew_0787 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001500605.1 PFAM: dienelactone hydrolase; KEGG: sfr:Sfri_0519 dienelactone hydrolase YP_001500606.1 KEGG: she:Shewmr4_0805 hypothetical protein YP_001500607.1 KEGG: slo:Shew_0791 spermine synthase YP_001500608.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sfr:Sfri_0522 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_001500609.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; KEGG: slo:Shew_0793 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001500610.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: slo:Shew_0794 diguanylate cyclase YP_001500611.1 KEGG: slo:Shew_0796 hypothetical protein YP_001500612.1 KEGG: slo:Shew_0797 hypothetical protein YP_001500613.1 KEGG: slo:Shew_0798 hypothetical protein YP_001500614.1 PFAM: FAD dependent oxidoreductase; KEGG: spc:Sputcn32_3055 FAD dependent oxidoreductase YP_001500615.1 TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter; KEGG: sdn:Sden_3160 chromate transporter YP_001500616.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: slo:Shew_0809 formate dehydrogenase, alpha subunit YP_001500617.1 PFAM: pentapeptide repeat protein; Ion transport 2 domain protein; KEGG: slo:Shew_0810 ion transport 2 domain protein YP_001500618.1 TIGRFAM: peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein; KEGG: slo:Shew_0811 peptide chain release factor 2 YP_001500619.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001500620.1 KEGG: slo:Shew_0813 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001500621.1 PFAM: pseudouridine synthase; KEGG: cps:CPS_1154 RNA pseudouridine synthase family protein YP_001500622.1 TIGRFAM: glucosamine-6-phosphate isomerase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: slo:Shew_0815 glucosamine-6-phosphate isomerase YP_001500623.1 KEGG: sfr:Sfri_3542 hypothetical protein YP_001500624.1 PFAM: nitroreductase; KEGG: sfr:Sfri_3203 nitroreductase YP_001500625.1 KEGG: mbu:Mbur_1476 cupin family protein YP_001500626.1 PFAM: peptidase U32; KEGG: shm:Shewmr7_0828 peptidase U32 YP_001500627.1 PFAM: protein of unknown function DUF1696; KEGG: slo:Shew_0819 protein of unknown function DUF1696 YP_001500628.1 PFAM: Fe-S metabolism associated SufE; KEGG: shn:Shewana3_0807 Fe-S metabolism associated SufE YP_001500629.1 TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; KEGG: son:SO_3789 aminotransferase, class V YP_001500630.1 PFAM: aldo/keto reductase; KEGG: slo:Shew_0736 aldo/keto reductase YP_001500631.1 PFAM: GCN5-related N-acetyltransferase; regulatory protein MarR; KEGG: slo:Shew_0737 transcriptional regulator, MarR family with acetyltransferase activity YP_001500632.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_001500633.1 PFAM: aromatic amino acid permease; KEGG: sbm:Shew185_3552 aromatic amino acid permease YP_001500634.1 KEGG: slo:Shew_0740 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001500635.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_0762 GCN5-related N-acetyltransferase YP_001500636.1 KEGG: sbm:Shew185_3550 hypothetical protein YP_001500637.1 PFAM: sodium:dicarboxylate symporter; KEGG: slo:Shew_0743 sodium:dicarboxylate symporter YP_001500638.1 PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: sbl:Sbal_0769 protein of unknown function DUF306, MetA and HslJ YP_001500639.1 KEGG: she:Shewmr4_0766 hypothetical protein YP_001500640.1 PFAM: GGDEF domain containing protein; KEGG: slo:Shew_0746 diguanylate cyclase YP_001500641.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sbm:Shew185_3545 acetyltransferase, GNAT family YP_001500642.1 KEGG: sfr:Sfri_0644 hypothetical protein YP_001500643.1 KEGG: shn:Shewana3_0553 hypothetical protein YP_001500644.1 KEGG: mmw:Mmwyl1_2727 hypothetical protein YP_001500646.1 KEGG: slo:Shew_3061 hypothetical protein YP_001500647.1 KEGG: slo:Shew_3061 hypothetical protein YP_001500648.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sfr:Sfri_0645 GCN5-related N-acetyltransferase YP_001500649.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001500650.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001500651.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_001500652.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001500653.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_001500654.1 PFAM: protein of unknown function DUF481; KEGG: slo:Shew_0756 protein of unknown function DUF481 YP_001500655.1 KEGG: sbm:Shew185_3534 transcriptional regulator, CadC YP_001500657.1 KEGG: slo:Shew_0762 hypothetical protein YP_001500658.1 TIGRFAM: PAS sensor protein; PFAM: PAS fold domain protein; KEGG: slo:Shew_0763 putative PAS/PAC sensor protein YP_001500659.1 PFAM: Radical SAM domain protein; KEGG: slo:Shew_0764 radical SAM domain protein YP_001500660.1 KEGG: sfr:Sfri_3563 transposase YP_001500661.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3562 integrase, catalytic region YP_001500662.1 PFAM: acriflavin resistance protein; KEGG: sbl:Sbal_0838 acriflavin resistance protein YP_001500663.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shn:Shewana3_3337 efflux transporter, RND family, MFP subunit YP_001500664.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_001500665.1 KEGG: slo:Shew_0768 methyltransferase small YP_001500666.1 PFAM: branched-chain amino acid transport system II carrier protein; KEGG: slo:Shew_0769 branched-chain amino acid transport system II carrier protein YP_001500667.1 TIGRFAM: tyrosine recombinase XerD; PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: sbm:Shew185_3524 tyrosine recombinase XerD YP_001500668.1 KEGG: son:SO_0951 thiol:disulfide interchange protein DsbC YP_001500669.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: slo:Shew_0772 single-stranded-DNA-specific exonuclease RecJ YP_001500670.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: ppr:PBPRA0970 putative transcriptional regulator, AsnC family YP_001500671.1 PFAM: protein of unknown function DUF1063; KEGG: ppr:PBPRB0240 hypothetical inner membrane protein YP_001500672.1 KEGG: vfi:VF0643 serine transporter YP_001500673.1 KEGG: rco:RC0850 hypothetical protein YP_001500674.1 PFAM: NUDIX hydrolase; KEGG: ppr:PBPRB0736 hypothetical protein YP_001500675.1 PFAM: FAD dependent oxidoreductase; KEGG: bba:Bd0322 D-amino acid dehydrogenase YP_001500676.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: ppr:PBPRB1132 putative transcriptional regulator YP_001500677.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: ppu:PP_3565 transporter, LysE family YP_001500678.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001500679.1 PFAM: protein of unknown function DUF808; KEGG: shm:Shewmr7_1013 protein of unknown function DUF808 YP_001500680.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: pha:PSHAa1702 hypothetical protein YP_001500681.1 PFAM: MORN variant repeat protein; KEGG: fnu:FN0738 hypothetical exported 24-amino acid repeat protein YP_001500682.1 KEGG: shn:Shewana3_3482 alkaline phosphatase YP_001500683.1 PFAM: phosphoribosyltransferase; KEGG: slo:Shew_0833 hypoxanthine-guanine phosphoribosyltransferase YP_001500684.1 KEGG: slo:Shew_0834 hypothetical protein YP_001500685.1 TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: son:SO_1059 aminopeptidase N YP_001500686.1 TIGRFAM: membrane lipoprotein lipid attachment site; KEGG: shn:Shewana3_0898 conserved hypothetical protein YP_001500687.1 PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: son:SO_1061 TPR domain protein YP_001500688.1 PFAM: SlyX family protein; KEGG: slo:Shew_0838 SlyX family protein YP_001500689.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase FKBP-type; KEGG: slo:Shew_0840 peptidylprolyl isomerase, FKBP-type YP_001500690.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_0841 uncharacterized conserved protein UCP006287 YP_001500691.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: slo:Shew_0842 two component transcriptional regulator, LuxR family YP_001500692.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: slo:Shew_0843 signal transduction histidine kinase, nitrate/nitrite-specific, NarQ YP_001500693.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_001500694.1 PFAM: isochorismatase hydrolase; KEGG: shw:Sputw3181_0699 isochorismatase hydrolase YP_001500695.1 PFAM: nitrogen regulatory protein P-II; KEGG: sfr:Sfri_0623 nitrogen regulatory protein P-II YP_001500696.1 PFAM: Rh family protein/ammonium transporter; KEGG: sfr:Sfri_0624 Rh family protein/ammonium transporter YP_001500697.1 KEGG: saz:Sama_0652 hypothetical protein YP_001500698.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: slo:Shew_0849 TPR repeat-containing protein YP_001500699.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001500700.1 KEGG: slo:Shew_0852 hypothetical protein YP_001500701.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: sfr:Sfri_0630 ABC transporter related YP_001500702.1 KEGG: slo:Shew_0854 hypothetical protein YP_001500703.1 KEGG: son:SO_0752 hypothetical protein YP_001500704.1 PFAM: Phosphoglycerate mutase; KEGG: she:Shewmr4_3352 phosphoglycerate mutase YP_001500705.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: shw:Sputw3181_0711 oxidoreductase FAD/NAD(P)-binding domain protein YP_001500706.1 PFAM: extracellular solute-binding protein family 1; KEGG: slo:Shew_0861 extracellular solute-binding protein, family 1 YP_001500707.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfr:Sfri_0637 binding-protein-dependent transport systems inner membrane component YP_001500708.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sbl:Sbal_0603 ABC transporter related YP_001500709.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: slo:Shew_0864 Dyp-type peroxidase family YP_001500710.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: slo:Shew_0865 cupin 2, conserved barrel domain protein YP_001500711.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_001500712.1 oxidizes malate to oxaloacetate YP_001500713.1 PFAM: Polyprenyl synthetase; KEGG: slo:Shew_0868 trans-hexaprenyltranstransferase YP_001500714.1 PFAM: ribosomal protein L21; KEGG: slo:Shew_0869 ribosomal protein L21 YP_001500715.1 involved in the peptidyltransferase reaction during translation YP_001500716.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001500717.1 PFAM: protein of unknown function DUF1212; KEGG: slo:Shew_0872 protein of unknown function DUF1212 YP_001500718.1 KEGG: sbm:Shew185_1040 hypothetical protein YP_001500719.1 PFAM: dihydrofolate reductase region; KEGG: shm:Shewmr7_3120 dihydrofolate reductase YP_001500720.1 KEGG: saz:Sama_2823 hypothetical protein YP_001500721.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: slo:Shew_0876 methyl-accepting chemotaxis sensory transducer YP_001500722.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_001500723.1 protein associated with Co2+ and Mg2+ efflux YP_001500724.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001500725.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001500726.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: she:Shewmr4_0907 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001500727.1 PFAM: OstA family protein; Organic solvent tolerance protein; KEGG: slo:Shew_0882 organic solvent tolerance protein YP_001500728.1 PFAM: aminoglycoside phosphotransferase; KEGG: shm:Shewmr7_3111 aminoglycoside phosphotransferase YP_001500729.1 PFAM: Nucleotidyl transferase; KEGG: shn:Shewana3_3204 nucleotidyl transferase YP_001500730.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_001500731.1 KEGG: slo:Shew_0886 hypothetical protein YP_001500732.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: shm:Shewmr7_3107 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein YP_001500733.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001500734.1 KEGG: slo:Shew_0889 hypothetical protein YP_001500735.1 PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_0890 secretion protein HlyD family protein YP_001500736.1 PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: slo:Shew_0892 AAA ATPase, central domain protein YP_001500737.1 KEGG: she:Shewmr4_3009 hypothetical protein YP_001500738.1 PFAM: protein of unknown function DUF1289; KEGG: slo:Shew_0894 protein of unknown function DUF1289 YP_001500739.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: shm:Shewmr7_3088 periplasmic sensor signal transduction histidine kinase YP_001500740.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: slo:Shew_0896 two component transcriptional regulator, winged helix family YP_001500741.1 KEGG: slo:Shew_0897 hypothetical protein YP_001500742.1 PFAM: MltA-interacting MipA family protein; KEGG: slo:Shew_0898 MltA-interacting MipA family protein YP_001500743.1 PFAM: GCN5-related N-acetyltransferase; KEGG: saz:Sama_2792 conserved hypothetical acetyltransferase YP_001500744.1 KEGG: shm:Shewmr7_3082 hypothetical protein YP_001500745.1 PFAM: Protein of unknown function DUF1971; KEGG: sbm:Shew185_1077 protein of unknown function DUF1971 YP_001500746.1 KEGG: shm:Shewmr7_1169 UspA domain protein YP_001500747.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sfr:Sfri_2218 short-chain dehydrogenase/reductase SDR YP_001500748.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: slo:Shew_0913 glyoxalase/bleomycin resistance protein/dioxygenase YP_001500749.1 PFAM: NADPH-dependent FMN reductase; KEGG: slo:Shew_0914 NADPH-dependent FMN reductase YP_001500750.1 PFAM: Helix-turn-helix type 11 domain protein; KEGG: sbl:Sbal_1011 putative transcriptional regulator YP_001500751.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: shw:Sputw3181_3146 pseudouridine synthase YP_001500752.1 PFAM: GPR1/FUN34/yaaH family protein; KEGG: vpa:VP0620 hypothetical protein YP_001500753.1 PFAM: major facilitator superfamily MFS_1; KEGG: slo:Shew_0920 major facilitator superfamily MFS_1 YP_001500754.1 PFAM: LrgB family protein; KEGG: son:SO_1048 hypothetical protein YP_001500755.1 PFAM: LrgA family protein; KEGG: shn:Shewana3_0885 LrgA family protein YP_001500756.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: she:Shewmr4_3051 transcriptional regulator, LysR family YP_001500757.1 PFAM: protein of unknown function UPF0057; KEGG: slo:Shew_0100 protein of unknown function UPF0057 YP_001500758.1 PFAM: AMMECR1 domain protein; KEGG: ppr:PBPRA1250 hypothetical protein YP_001500759.1 PFAM: protein of unknown function DUF52; KEGG: eba:ebA6549 hypothetical protein YP_001500760.1 PFAM: Radical SAM domain protein; KEGG: slo:Shew_0932 radical SAM domain protein YP_001500761.1 KEGG: slo:Shew_0921 hypothetical protein YP_001500762.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: slo:Shew_0922 methyl-accepting chemotaxis sensory transducer YP_001500763.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001500764.1 PFAM: DNA polymerase III chi subunit HolC; KEGG: sbl:Sbal_3111 DNA polymerase III chi subunit, HolC YP_001500765.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: aha:AHA_0632 ATP-dependent RNA helicase, dead box family YP_001500766.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: vfi:VFA0031 transcriptional regulators, LysR family YP_001500767.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: vfi:VFA0032 thioredoxin peroxidase YP_001500768.1 KEGG: swi:Swit_1025 hypothetical protein YP_001500769.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: shw:Sputw3181_3757 protein of unknown function DUF21 YP_001500770.1 PFAM: EAL domain protein; response regulator receiver; KEGG: aha:AHA_0909 response regulator YP_001500771.1 PFAM: extracellular solute-binding protein family 3; response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: cyb:CYB_0507 sensory box histidine kinase/response regulator YP_001500772.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001500773.1 PFAM: permease YjgP/YjgQ family protein; KEGG: slo:Shew_0940 permease YjgP/YjgQ family protein YP_001500774.1 PFAM: permease YjgP/YjgQ family protein; KEGG: sbm:Shew185_3117 permease YjgP/YjgQ family protein YP_001500775.1 PFAM: RDD domain containing protein; KEGG: slo:Shew_0942 RDD domain containing protein YP_001500776.1 KEGG: slo:Shew_0943 hypothetical protein YP_001500777.1 PFAM: GCN5-related N-acetyltransferase; KEGG: slo:Shew_0944 GCN5-related N-acetyltransferase YP_001500778.1 PFAM: peptidase M32 carboxypeptidase Taq metallopeptidase; KEGG: shn:Shewana3_2999 peptidase M32, carboxypeptidase Taq metallopeptidase YP_001500779.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; protease-associated PA domain protein; KEGG: slo:Shew_2720 peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001500780.1 KEGG: son:SO_1380 hypothetical protein YP_001500781.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: shm:Shewmr7_2892 DEAD/DEAH box helicase domain protein YP_001500782.1 PFAM: creatinase; peptidase M24; KEGG: shm:Shewmr7_2890 peptidase M24 YP_001500783.1 PFAM: major facilitator superfamily MFS_1; KEGG: slo:Shew_0953 major facilitator superfamily MFS_1 YP_001500784.1 PFAM: creatinase; peptidase M24; KEGG: slo:Shew_0955 peptidase M24 YP_001500785.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: shn:Shewana3_2983 peptidylprolyl isomerase, FKBP-type YP_001500786.1 PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: son:SO_A0114 outer membrane protein A YP_001500787.1 PFAM: Ig domain protein group 2 domain protein; KEGG: sfr:Sfri_1018 Ig domain protein, group 2 domain protein YP_001500788.1 PFAM: Ig domain protein group 2 domain protein; KEGG: sun:SUN_2457 hypothetical protein YP_001500789.1 PFAM: Cold-shock protein DNA-binding; protein of unknown function DUF1294; SMART: Cold shock protein; KEGG: sdn:Sden_2865 protein of unknown function DUF1294 YP_001500790.1 PFAM: regulatory protein ArsR; KEGG: ppr:PBPRA2744 hypothetical transcriptional regulator, ArsR family YP_001500791.1 KEGG: shm:Shewmr7_2880 hypothetical protein YP_001500792.1 PFAM: protein of unknown function DUF368; KEGG: slo:Shew_0960 protein of unknown function DUF368 YP_001500793.1 KEGG: slo:Shew_0961 hypothetical protein YP_001500794.1 KEGG: slo:Shew_0962 hypothetical protein YP_001500795.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_0963 hypothetical protein YP_001500796.1 PFAM: protein of unknown function DUF861 cupin_3; KEGG: slo:Shew_0964 protein of unknown function DUF861, cupin_3 YP_001500797.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: slo:Shew_0965 methylmalonate-semialdehyde dehydrogenase YP_001500798.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_001500799.1 PFAM: aldehyde dehydrogenase; KEGG: shw:Sputw3181_3079 aldehyde dehydrogenase (NAD(+)) YP_001500800.1 PFAM: regulatory protein MerR; Methyltransferase type 11; Methyltransferase type 12; KEGG: dps:DPPB100 probable transcription regulator YP_001500801.1 PFAM: GCN5-related N-acetyltransferase; KEGG: dde:Dde_3171 acetyltransferase YP_001500802.1 TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: sfr:Sfri_1665 putative adenylyl cyclase CyaB YP_001500803.1 TIGRFAM: aspartate racemase; PFAM: Asp/Glu racemase; KEGG: dps:DP1920 hypothetical protein YP_001500804.1 PFAM: FAD dependent oxidoreductase; KEGG: she:Shewmr4_2922 FAD dependent oxidoreductase YP_001500805.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: shn:Shewana3_3100 transcriptional regulator, XRE family YP_001500806.1 PFAM: peptidase C26; KEGG: slo:Shew_0971 peptidase C26 YP_001500807.1 PFAM: glutamine synthetase catalytic region; KEGG: slo:Shew_0972 glutamate--ammonia ligase YP_001500808.1 PFAM: extracellular solute-binding protein family 1; KEGG: slo:Shew_0973 extracellular solute-binding protein, family 1 YP_001500809.1 KEGG: slo:Shew_0974 spermidine/putrescine ABC transporter ATPase subunit; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001500810.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_0975 binding-protein-dependent transport systems inner membrane component YP_001500811.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_0976 binding-protein-dependent transport systems inner membrane component YP_001500812.1 PFAM: FAD dependent oxidoreductase; KEGG: slo:Shew_0977 FAD dependent oxidoreductase YP_001500813.1 TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: shn:Shewana3_3092 succinic semialdehyde dehydrogenase YP_001500814.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_001500815.1 PFAM: UspA domain protein; KEGG: slo:Shew_3101 UspA domain protein YP_001500816.1 KEGG: vha:VIBHAR_05467 hypothetical protein YP_001500817.1 CcoN; FixN YP_001500818.1 PFAM: cytochrome C oxidase mono-heme subunit/FixO; KEGG: vha:VIBHAR_05465 hypothetical protein YP_001500819.1 PFAM: cytochrome c class I; KEGG: vha:VIBHAR_05464 hypothetical protein YP_001500820.1 TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma-70; PFAM: sigma-70 1.1 domain protein; sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70 non-essential domain protein; sigma-70 region 1.2; KEGG: slo:Shew_0996 RNA polymerase, sigma 70 subunit, RpoD family YP_001500821.1 KEGG: slo:Shew_0997 DNA primase; TIGRFAM: DNA primase; PFAM: zinc finger CHC2-family protein; TOPRIM domain protein; DNA primase DnaG DnaB-binding; DNA primase catalytic core domain; SMART: Toprim sub domain protein YP_001500822.1 KEGG: slo:Shew_0998 GatB/YqeY domain protein YP_001500823.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001500824.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001500825.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase alpha subunit; KEGG: son:SO_3563 SM-20 domain protein YP_001500826.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001500827.1 TIGRFAM: dihydroneopterin aldolase; KEGG: slo:Shew_1002 dihydroneopterin aldolase YP_001500828.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: she:Shewmr4_2901 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_001500829.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001500830.1 KEGG: slo:Shew_1005 rRNA (guanine-N(1)-)-methyltransferase YP_001500831.1 PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: slo:Shew_1006 ErfK/YbiS/YcfS/YnhG family protein YP_001500832.1 KEGG: slo:Shew_1007 major outer membrane lipoprotein, putative YP_001500833.1 PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; KEGG: slo:Shew_1008 metal dependent phosphohydrolase YP_001500834.1 PFAM: Peptidoglycan-binding domain 1 protein; SMART: AAA ATPase; KEGG: slo:Shew_1009 peptidoglycan-binding domain 1 protein YP_001500835.1 KEGG: sbm:Shew185_1201 general secretion pathway protein B YP_001500836.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001500837.1 Catalyzes the conversion of carbamoyl phosphate and l-aspartate to yield orthophosphate and n-carbamoyl-l-aspartate YP_001500838.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001500839.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sbm:Shew185_0291 TonB-dependent receptor YP_001500840.1 KEGG: slo:Shew_3159 uncharacterized FlgJ-related protein-like YP_001500841.1 PFAM: cytochrome c class I; KEGG: sbl:Sbal_0009 monoheme cytochrome c YP_001500842.1 KEGG: son:SO_0716 monoheme cytochrome c, putative YP_001500843.1 PFAM: oxidoreductase molybdopterin binding; Mo-co oxidoreductase dimerisation domain; KEGG: sbl:Sbal_0007 oxidoreductase, molybdopterin binding YP_001500844.1 PFAM: cytochrome c class I; KEGG: sbl:Sbal_0006 monoheme cytochrome c YP_001500845.1 PFAM: Chloride channel core; KEGG: slo:Shew_1015 Cl-channel, voltage-gated family protein YP_001500846.1 KEGG: slo:Shew_1016 hypothetical protein YP_001500847.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_001500848.1 KEGG: slo:Shew_1018 hypothetical protein YP_001500849.1 KEGG: shw:Sputw3181_3039 hypothetical protein YP_001500850.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure YP_001500851.1 PFAM: Alkaline phosphatase; KEGG: vpa:VPA1073 putative alkaline phosphatase YP_001500852.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: she:Shewmr4_2884 peptidase S9, prolyl oligopeptidase active site domain protein YP_001500853.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: vvy:VV0250 outer membrane receptor protein YP_001500854.1 PFAM: transcriptional regulator domain protein; WD40 domain protein beta Propeller; KEGG: shm:Shewmr7_2965 transcriptional regulator domain protein YP_001500855.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001500856.1 PFAM: peptidase M23B; Opacity-associated protein A domain protein; KEGG: slo:Shew_1021 peptidase M23B YP_001500857.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001500858.1 KEGG: shm:Shewmr7_2961 hypothetical protein YP_001500859.1 KEGG: slo:Shew_1023 hypothetical protein YP_001500860.1 PFAM: protein of unknown function UPF0126; KEGG: slo:Shew_1024 protein of unknown function UPF0126 YP_001500861.1 KEGG: slo:Shew_1025 hypothetical protein YP_001500862.1 PFAM: cobalamin biosynthesis protein CbiB; KEGG: shn:Shewana3_3053 cobalamin biosynthesis protein CbiB YP_001500863.1 PFAM: purine or other phosphorylase family 1; KEGG: shn:Shewana3_3052 purine and other phosphorylases, family 1 YP_001500864.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; CHASE3 domain protein; KEGG: pin:Ping_3077 diguanylate cyclase YP_001500865.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cps:CPS_0291 acetyltransferase, GNAT family YP_001500866.1 PFAM: regulatory protein MarR; KEGG: sfr:Sfri_1943 transcriptional regulator, MarR family protein YP_001500867.1 PFAM: conserved hypothetical protein; KEGG: sfr:Sfri_1944 hypothetical protein YP_001500868.1 KEGG: sfr:Sfri_1945 putative transporter, BCCT family protein YP_001500869.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_001500870.1 catalyzes the formation of betaine from betaine aldehyde YP_001500871.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_001500872.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: sfr:Sfri_3408 inosine/uridine-preferring nucleoside hydrolase YP_001500873.1 PFAM: regulatory protein DeoR; PfkB domain protein; Helix-turn-helix type 11 domain protein; Phosphomethylpyrimidine kinase type-1; KEGG: sfr:Sfri_3407 ribokinase YP_001500874.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001500875.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_001500876.1 KEGG: slo:Shew_1033 conserved hypothetical radical SAM protein; TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001500877.1 PFAM: Hpt domain protein; KEGG: shm:Shewmr7_2951 Hpt protein YP_001500878.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_1035 transcriptional regulator, LysR family YP_001500879.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3562 integrase, catalytic region YP_001500880.1 KEGG: sfr:Sfri_3563 transposase YP_001500881.1 KEGG: sbm:Shew185_1226 putative adenylate/guanylate cyclase YP_001500882.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_001500883.1 hydrolyzes diadenosine polyphosphate YP_001500884.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; GAF domain protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: shm:Shewmr7_2946 PTSINtr with GAF domain, PtsP YP_001500885.1 PFAM: protein of unknown function DUF81; KEGG: shm:Shewmr7_2945 protein of unknown function DUF81 YP_001500886.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001500887.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_001500888.1 KEGG: slo:Shew_1043 hypothetical protein YP_001500889.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_001500890.1 PFAM: protein of unknown function DUF339; KEGG: sfr:Sfri_2938 protein of unknown function DUF339 YP_001500891.1 KEGG: sbm:Shew185_1237 hypothetical protein YP_001500892.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001500893.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001500894.1 PFAM: Anti sigma-E protein RseA family protein; Anti sigma-E protein RseA domain protein; KEGG: slo:Shew_1049 anti sigma-E protein, RseA YP_001500895.1 PFAM: MucB/RseB family protein; KEGG: she:Shewmr4_2852 sigma E regulatory protein, MucB/RseB YP_001500896.1 PFAM: Positive regulator of sigma(E) RseC/MucC; KEGG: sbl:Sbal_1198 positive regulator of sigma E, RseC/MucC YP_001500897.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001500898.1 KEGG: slo:Shew_1053 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein YP_001500899.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001500900.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001500901.1 TIGRFAM: DNA repair protein RecO; PFAM: Recombination protein O RecO; KEGG: slo:Shew_1056 DNA repair protein RecO YP_001500902.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001500903.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001500904.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bsu:BG10906 spermine/spermidine acetyltransferase YP_001500905.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: zmo:ZMO1573 predicted iron-dependent peroxidase YP_001500906.1 KEGG: slo:Shew_2460 hypothetical protein YP_001500907.1 PFAM: protein of unknown function DUF962; KEGG: slo:Shew_1059 protein of unknown function DUF962 YP_001500908.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: slo:Shew_1060 protein of unknown function DUF21 YP_001500909.1 PFAM: cytochrome c assembly protein; KEGG: slo:Shew_1061 cytochrome c assembly protein YP_001500910.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_001500911.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001500912.1 Essential for efficient processing of 16S rRNA YP_001500913.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001500914.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001500915.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_001500916.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_001500917.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_001500918.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: slo:Shew_1070 oxidoreductase FAD-binding domain protein YP_001500919.1 KEGG: sfr:Sfri_2914 hypothetical protein YP_001500920.1 PFAM: sodium/hydrogen exchanger; KEGG: sbm:Shew185_1263 sodium/hydrogen exchanger YP_001500921.1 TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: sbm:Shew185_1264 chorismate mutase YP_001500922.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: slo:Shew_1073 sigma 54 modulation protein/ribosomal protein S30EA YP_001500923.1 PFAM: cytochrome B561; KEGG: sbl:Sbal_1222 cytochrome b561 YP_001500924.1 PFAM: cytochrome c class II; KEGG: slo:Shew_1075 cytochrome c, class II YP_001500925.1 TIGRFAM: trp operon repressor; PFAM: Trp repressor; KEGG: slo:Shew_1076 Trp operon repressor YP_001500926.1 KEGG: shn:Shewana3_1137 hypothetical protein YP_001500927.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: slo:Shew_1078 peptidylprolyl isomerase, FKBP-type YP_001500928.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001500929.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001500930.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001500931.1 KEGG: sbm:Shew185_1274 hypothetical protein YP_001500932.1 KEGG: slo:Shew_1083 apurinic endonuclease Apn1; TIGRFAM: apurinic endonuclease Apn1; PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease family 2 YP_001500933.1 PFAM: Hemerythrin HHE cation binding domain protein; KEGG: sfr:Sfri_2903 hemerythrin HHE cation binding domain protein YP_001500934.1 KEGG: son:SO_3548 hypothetical protein YP_001500935.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001500936.1 KEGG: slo:Shew_1089 transaldolase; TIGRFAM: transaldolase; PFAM: Transaldolase YP_001500937.1 PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: slo:Shew_1090 OmpA/MotB domain protein YP_001500938.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: slo:Shew_1091 phosphoketolase YP_001500939.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: son:SO_3541 sodium:alanine symporter family protein YP_001500940.1 PFAM: protein of unknown function DUF328; KEGG: slo:Shew_1093 protein of unknown function DUF328 YP_001500941.1 PFAM: regulatory protein ArsR; KEGG: saz:Sama_0920 transcriptional regulator HlyU YP_001500942.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001500943.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: son:SO_3534 MviN protein YP_001500944.1 TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: slo:Shew_1098 riboflavin biosynthesis protein RibF YP_001500945.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001500946.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001500947.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: slo:Shew_1101 peptidylprolyl isomerase, FKBP-type YP_001500948.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001500949.1 TIGRFAM: type IV pilus modification protein PilV; KEGG: son:SO_3528 type IV pilus assembly protein PilV YP_001500950.1 KEGG: sbl:Sbal_1059 type IV pilus assembly protein PilW YP_001500951.1 KEGG: sbm:Shew185_1127 type IV pilus assembly protein PilX YP_001500952.1 KEGG: sdn:Sden_2716 type IV pilin biogenesis protein, putative YP_001500953.1 KEGG: shw:Sputw3181_3098 methylation site containing protein YP_001500954.1 KEGG: she:Shewmr4_2948 hypothetical protein YP_001500955.1 KEGG: sdn:Sden_2713 type IV pilus biogenesis protein, putative YP_001500956.1 KEGG: slo:Shew_1109 type IV pilus biogenesis protein, putative YP_001500957.1 PFAM: nitrogen regulatory protein P-II; KEGG: saz:Sama_0935 nitrogen regulatory protein P-II YP_001500958.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: saz:Sama_0937 transcriptional regulator, LacI family YP_001500959.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: slo:Shew_1112 TonB-dependent receptor YP_001500960.1 PFAM: tryptophan halogenase; KEGG: slo:Shew_1113 tryptophan halogenase YP_001500961.1 PFAM: SapC family protein; KEGG: slo:Shew_1114 SapC family protein YP_001500962.1 PFAM: Carbohydrate-binding chitobiase/hexosaminidase-type domain protein; glycoside hydrolase family 20 domain protein; Glycoside hydrolase, family 20, catalytic core; KEGG: spc:Sputcn32_1075 beta-N-acetylhexosaminidase YP_001500963.1 PFAM: ATPase BadF/BadG/BcrA/BcrD type; KEGG: she:Shewmr4_2935 ATPase, BadF/BadG/BcrA/BcrD type YP_001500964.1 KEGG: son:SO_3505 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase YP_001500965.1 KEGG: slo:Shew_1118 hypothetical protein YP_001500966.1 TIGRFAM: glucose/galactose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: saz:Sama_0948 multiple antibiotic resistance (MarC)-related protein YP_001500967.1 KEGG: mmw:Mmwyl1_3491 transposase YP_001500968.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3340 integrase, catalytic region YP_001500969.1 PFAM: Fe(II) trafficking protein YggX; KEGG: slo:Shew_1122 Fe(II) trafficking protein YggX YP_001500970.1 TIGRFAM: A/G-specific adenine glycosylase; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: she:Shewmr4_1180 A/G-specific adenine glycosylase YP_001500971.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001500972.1 PFAM: protein of unknown function DUF469; KEGG: sdn:Sden_2696 protein of unknown function DUF469 YP_001500973.1 catalyzes the formation of glutamate from glutamine YP_001500974.1 KEGG: slo:Shew_1127 hypothetical protein YP_001500975.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_1128 transcriptional regulator, LysR family YP_001500976.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: sdn:Sden_3445 transposase IS116/IS110/IS902 YP_001500979.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: cps:CPS_3436 C4-dicarboxylate transporter/malic acid transport protein YP_001500980.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: vvy:VVA1368 putative transcriptional regulator YP_001500981.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: lpn:lpg1202 cytochrome D ubiquinol oxidase, subunit I YP_001500982.1 PFAM: protein of unknown function DUF885; KEGG: sbl:Sbal_3032 protein of unknown function DUF885 YP_001500983.1 KEGG: sfr:Sfri_2866 putative oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001500984.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001500985.1 KEGG: slo:Shew_1133 hypothetical protein YP_001500986.1 PFAM: protein of unknown function DUF167; KEGG: she:Shewmr4_1190 hypothetical protein YP_001500987.1 PFAM: protein of unknown function YGGT; KEGG: slo:Shew_1135 protein of unknown function YGGT YP_001500988.1 KEGG: sfr:Sfri_2861 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_001500989.1 PFAM: alanine racemase domain protein; KEGG: shw:Sputw3181_1324 alanine racemase domain protein YP_001500990.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: slo:Shew_1138 twitching motility protein YP_001500991.1 KEGG: shw:Sputw3181_1326 twitching motility protein; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001500992.1 PFAM: ferrochelatase; KEGG: sfr:Sfri_2852 ferrochelatase YP_001500993.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001500994.1 PFAM: protein of unknown function DUF179; KEGG: sfr:Sfri_2850 protein of unknown function DUF179 YP_001500995.1 involved in start site selection during the initiation of translation YP_001500996.1 KEGG: sbl:Sbal_3017 hypothetical protein YP_001500997.1 KEGG: slo:Shew_1147 hypothetical protein YP_001500998.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: cps:CPS_0421 transcription regulator, LysR family YP_001500999.1 PFAM: transmembrane pair domain protein; KEGG: vha:VIBHAR_01850 hypothetical protein YP_001501000.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: pfl:PFL_2240 receptor, putative YP_001501001.1 PFAM: OmpA/MotB domain protein; KEGG: sbm:Shew185_3027 OmpA/MotB domain protein YP_001501002.1 PFAM: MscS Mechanosensitive ion channel; KEGG: slo:Shew_1152 MscS mechanosensitive ion channel YP_001501003.1 PFAM: protein of unknown function UPF0126; KEGG: sfr:Sfri_0596 protein of unknown function UPF0126 YP_001501004.1 PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sbm:Shew185_3026 threonine aldolase YP_001501005.1 KEGG: she:Shewmr4_3368 hypothetical protein YP_001501006.1 PFAM: Alkaline phosphatase; KEGG: slo:Shew_1157 alkaline phosphatase YP_001501007.1 PFAM: Alkaline phosphatase; KEGG: slo:Shew_1158 alkaline phosphatase YP_001501008.1 KEGG: slo:Shew_1160 hypothetical protein YP_001501009.1 KEGG: rme:Rmet_6285 hypothetical protein YP_001501010.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: slo:Shew_1161 NADH dehydrogenase YP_001501011.1 KEGG: slo:Shew_1162 hypothetical protein YP_001501012.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_1163 efflux transporter, RND family, MFP subunit YP_001501013.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: slo:Shew_1164 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family YP_001501014.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: slo:Shew_1166 iron-containing alcohol dehydrogenase YP_001501016.1 PFAM: protein of unknown function DUF88; KEGG: sbm:Shew185_3175 protein of unknown function DUF88 YP_001501017.1 PFAM: acriflavin resistance protein; KEGG: sbl:Sbal_3171 acriflavin resistance protein YP_001501018.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shw:Sputw3181_1226 efflux transporter, RND family, MFP subunit YP_001501019.1 PFAM: metallophosphoesterase; KEGG: shn:Shewana3_1086 metallophosphoesterase YP_001501020.1 PFAM: acyltransferase 3; KEGG: vvy:VVA1443 hypothetical protein YP_001501021.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001501022.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001501023.1 PFAM: ATP-cone domain protein; KEGG: slo:Shew_1186 ATP-cone domain protein YP_001501024.1 KEGG: she:Shewmr4_1096 riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein YP_001501025.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001501026.1 TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; KEGG: slo:Shew_1189 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_001501027.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001501028.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001501029.1 KEGG: shw:Sputw3181_1239 thiamine-monophosphate kinase; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein domain protein YP_001501030.1 PFAM: phosphatidylglycerophosphatase A; KEGG: sbm:Shew185_3152 phosphatidylglycerophosphatase A YP_001501031.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: slo:Shew_1196 DNA repair protein RecN YP_001501032.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: sdn:Sden_3445 transposase IS116/IS110/IS902 YP_001501033.1 PFAM: AAA-4 family protein; KEGG: bja:blr0871 hypothetical protein YP_001501034.1 PFAM: Pirin domain protein; KEGG: cps:CPS_1295 conserved hypothetical protein YP_001501035.1 KEGG: cps:CPS_1775 putative glutathione S-transferase YP_001501036.1 PFAM: DoxX family protein; KEGG: pha:PSHAb0104 putative membrane DoxD-like family protein YP_001501037.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pha:PSHAb0105 putative transcriptional regulator (LysR family) YP_001501038.1 PFAM: response regulator receiver; KEGG: vha:VIBHAR_06171 hypothetical protein YP_001501039.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: vha:VIBHAR_06169 hypothetical protein YP_001501040.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: son:SO_3460 transcriptional regulator, LysR family YP_001501041.1 PFAM: protein of unknown function DUF416; KEGG: slo:Shew_1199 protein of unknown function DUF416 YP_001501042.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_001501043.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_001501044.1 KEGG: slo:Shew_1202 (p)ppGpp synthetase I, SpoT/RelA; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; RelA/SpoT domain protein YP_001501045.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001501046.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001501047.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001501048.1 PFAM: Septum formation initiator; KEGG: slo:Shew_1206 septum formation initiator YP_001501049.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001501050.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001501051.1 PFAM: tRNA pseudouridine synthase D TruD; KEGG: sbl:Sbal_3123 pseudouridylate synthase YP_001501052.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001501053.1 KEGG: sdn:Sden_1202 protein-L-isoaspartate O-methyltransferase; TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_001501054.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; KEGG: slo:Shew_1212 peptidase M23B YP_001501055.1 TIGRFAM: RNA polymerase sigma factor RpoS; RNA polymerase sigma-70; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70 region 1.2; KEGG: slo:Shew_1213 RNA polymerase, sigma 70 subunit, RpoD family YP_001501056.1 This protein performs the mismatch recognition step during the DNA repair process YP_001501057.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001501058.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001501059.1 affects carbohydrate metabolism; has regulatory role in many processes YP_001501060.1 TIGRFAM: sodium pump decarboxylase, gamma subunit; PFAM: sodium pump decarboxylase gamma subunit; KEGG: sfr:Sfri_1065 sodium pump decarboxylases, gamma subunit YP_001501061.1 catalyzes the formation of pyruvate from oxaloacetate YP_001501062.1 KEGG: sfr:Sfri_1067 sodium ion-translocating decarboxylase, beta subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit YP_001501063.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: csa:Csal_1188 transcriptional regulator, LysR family YP_001501064.1 PFAM: Porphyromonas-type peptidyl-arginine deiminase; KEGG: pen:PSEEN2191 porphyromonas-type peptidyl-arginine deiminase YP_001501065.1 PFAM: extracellular solute-binding protein family 1; KEGG: pen:PSEEN2900 putrescine ABC transporter, periplasmic putrescine-binding protein YP_001501066.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: vpa:VP1774 putative carbon-nitrogen hydrolase YP_001501067.1 KEGG: slo:Shew_1223 hypothetical protein YP_001501068.1 PFAM: sodium:dicarboxylate symporter; KEGG: slo:Shew_1224 sodium:dicarboxylate symporter YP_001501069.1 PFAM: peptidase M16 domain protein; KEGG: slo:Shew_1226 peptidase M16 domain protein YP_001501070.1 involved in the first step of glutathione biosynthesis YP_001501071.1 KEGG: son:SO_3558 hypothetical protein YP_001501072.1 KEGG: slo:Shew_1229 hypothetical protein YP_001501073.1 KEGG: slo:Shew_1230 phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_001501074.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; KEGG: sbl:Sbal_1039 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001501075.1 KEGG: slo:Shew_1232 hypothetical protein YP_001501076.1 KEGG: shn:Shewana3_2001 hypothetical protein YP_001501077.1 PFAM: peptidase S41; WD40 domain protein beta Propeller; KEGG: slo:Shew_1234 peptidase S41 YP_001501078.1 PFAM: secretion protein HlyD family protein; KEGG: ppr:PBPRB1792 hypothetical secretion protein YP_001501079.1 KEGG: ppr:PBPRB1793 hypothetical protein YP_001501080.1 KEGG: slo:Shew_2686 putative lipoprotein YP_001501081.1 PFAM: OsmC family protein; KEGG: sbm:Shew185_1278 OsmC family protein YP_001501082.1 KEGG: sbl:Sbal_1233 hypothetical protein YP_001501083.1 KEGG: sbm:Shew185_1279 hypothetical protein YP_001501084.1 PFAM: PepSY-associated TM helix domain protein; KEGG: spc:Sputcn32_2728 PepSY-associated TM helix domain protein YP_001501085.1 KEGG: sbl:Sbal_0110 hypothetical protein YP_001501086.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: slo:Shew_1241 sigma 54 modulation protein/ribosomal protein S30EA YP_001501087.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: vha:VIBHAR_05273 hypothetical protein YP_001501088.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: vpa:VPA0465 putative NAD(P)H oxidoreductase YP_001501089.1 PFAM: NnrS family protein; KEGG: shw:Sputw3181_3742 NnrS family protein YP_001501090.1 PFAM: cytochrome c552; KEGG: slo:Shew_0505 nitrite reductase (cytochrome; ammonia-forming) YP_001501092.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: pfl:PFL_0202 transcriptional regulator, AraC family YP_001501093.1 PFAM: beta-lactamase domain protein; KEGG: pfo:Pfl_2280 beta-lactamase-like YP_001501095.1 KEGG: mul:MUL_0516 hypothetical protein YP_001501096.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001501097.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001501098.1 KEGG: cps:CPS_3362 putative lipoprotein YP_001501099.1 KEGG: vfi:VFA0120 hypothetical cytosolic protein YP_001501100.1 PFAM: glycosyl transferase group 1; KEGG: drm:Dred_2323 glycosyl transferase, group 1 YP_001501101.1 PFAM: extracellular solute-binding protein family 3; sodium:dicarboxylate symporter; KEGG: slo:Shew_3001 extracellular solute-binding protein, family 3 YP_001501102.1 KEGG: rde:RD1_0117 hypothetical protein YP_001501103.1 KEGG: cps:CPS_1463 hypothetical protein YP_001501105.1 PFAM: EAL domain protein; KEGG: ppr:PBPRB0827 hypothetical protein YP_001501106.1 PFAM: CBS domain containing protein; KEGG: cps:CPS_1349 CBS domain protein YP_001501107.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds YP_001501108.1 PFAM: PEBP family protein; KEGG: vfi:VFA0932 putative phospholipid-binding protein YP_001501109.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: vfi:VFA0931 transcriptional regulatory, AraC-like YP_001501110.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: slo:Shew_1931 alkylphosphonate utilization operon protein PhnA YP_001501111.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: shm:Shewmr7_0453 transcriptional regulator, AraC family YP_001501112.1 TIGRFAM: alkylhydroperoxidase-like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: she:Shewmr4_3500 alkylhydroperoxidase-like protein, AhpD family YP_001501113.1 PFAM: protein of unknown function DUF417; KEGG: aha:AHA_4046 MC21 protein YP_001501114.1 KEGG: slo:Shew_1250 hypothetical protein YP_001501115.1 KEGG: slo:Shew_1251 hypothetical protein YP_001501116.1 KEGG: slo:Shew_1252 transposase YP_001501117.1 PFAM: integrase family protein; KEGG: slo:Shew_1254 phage integrase family protein YP_001501118.1 KEGG: shm:Shewmr7_1773 hypothetical protein YP_001501119.1 PFAM: YagBYeeUYfjZ family protein; KEGG: shn:Shewana3_1802 YagBYeeUYfjZ family protein YP_001501120.1 KEGG: shm:Shewmr7_1775 hypothetical protein YP_001501121.1 PFAM: DNA repair protein RadC; KEGG: shm:Shewmr7_1776 DNA repair protein RadC YP_001501122.1 PFAM: Prophage CP4-57 regulatory; KEGG: shm:Shewmr7_1777 phage transcriptional regulator, AlpA YP_001501124.1 KEGG: vvy:VV2215 hypothetical protein YP_001501125.1 KEGG: ajs:Ajs_3602 hypothetical protein YP_001501126.1 KEGG: ajs:Ajs_3601 hypothetical protein YP_001501127.1 KEGG: pna:Pnap_4443 hypothetical protein YP_001501128.1 KEGG: pna:Pnap_4444 hypothetical protein YP_001501129.1 KEGG: vvy:VV2212 hypothetical protein YP_001501130.1 KEGG: vvy:VV2211 hypothetical protein YP_001501131.1 PFAM: helicase domain protein; KEGG: vvy:VV2210 hypothetical protein YP_001501132.1 KEGG: sfu:Sfum_1322 DNA-cytosine methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase YP_001501133.1 PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases; KEGG: ava:Ava_1325 SNF2-related helicase YP_001501134.1 KEGG: ava:Ava_C0223 hypothetical protein YP_001501135.1 PFAM: helicase domain protein; KEGG: sth:STH1306 putative DNA helicase YP_001501136.1 KEGG: sth:STH1305 hypothetical protein YP_001501137.1 KEGG: sth:STH1304 hypothetical protein YP_001501138.1 KEGG: ecj:JW2611 hypothetical protein YP_001501139.1 KEGG: ecj:JW5418 hypothetical protein YP_001501140.1 KEGG: spc:Sputcn32_2917 hypothetical protein YP_001501141.1 PFAM: helix-turn-helix domain protein; KEGG: slo:Shew_1266 transcriptional regulator, XRE family YP_001501142.1 KEGG: slo:Shew_1265 hypothetical protein YP_001501143.1 PFAM: integrase family protein; KEGG: vvy:VV0817 phage integrase YP_001501144.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001501145.1 PFAM: cyclase/dehydrase; KEGG: slo:Shew_1269 cyclase/dehydrase YP_001501146.1 PFAM: protein of unknown function UPF0125; KEGG: sbm:Shew185_1300 protein of unknown function UPF0125 YP_001501147.1 PFAM: SmpA/OmlA domain protein; KEGG: slo:Shew_1271 SmpA/OmlA domain protein YP_001501148.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: slo:Shew_1272 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase YP_001501149.1 KEGG: son:SO_1479 hypothetical protein YP_001501150.1 KEGG: saz:Sama_2383 hypothetical protein YP_001501151.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO_1480 GGDEF family protein YP_001501152.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001501153.1 PFAM: Metal-dependent hydrolase HDOD; KEGG: slo:Shew_1277 putative signal transduction protein YP_001501154.1 KEGG: sbl:Sbal_3009 hypothetical protein YP_001501155.1 PFAM: protein of unknown function DUF980; KEGG: son:SO_3335 hypothetical protein YP_001501156.1 KEGG: slo:Shew_1280 transcriptional regulator, CopG family YP_001501157.1 KEGG: slo:Shew_1281 hypothetical protein YP_001501158.1 KEGG: slo:Shew_1282 hypothetical protein YP_001501159.1 KEGG: slo:Shew_1283 NrfJ-related protein YP_001501160.1 PFAM: GCN5-related N-acetyltransferase; KEGG: slo:Shew_1284 GCN5-related N-acetyltransferase YP_001501161.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sbm:Shew185_3014 GCN5-related N-acetyltransferase YP_001501162.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: slo:Shew_1285 5'-nucleotidase YP_001501163.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; KEGG: sbm:Shew185_3009 protein of unknown function DUF21 YP_001501164.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001501165.1 KEGG: slo:Shew_1288 type IV pilus biogenesis/stability protein PilW; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001501166.1 KEGG: saz:Sama_2366 hypothetical protein YP_001501167.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001501168.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001501169.1 KEGG: slo:Shew_1292 tetratricopeptide TPR_4 YP_001501170.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_001501171.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001501174.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001501175.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001501176.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001501177.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: shm:Shewmr7_1307 CMP/dCMP deaminase, zinc-binding protein YP_001501178.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_001501179.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001501180.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: slo:Shew_1302 cytochrome bd ubiquinol oxidase, subunit I YP_001501181.1 KEGG: slo:Shew_1303 cytochrome d ubiquinol oxidase, subunit II; TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II YP_001501182.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: slo:Shew_1304 cyd operon protein YbgT YP_001501184.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: slo:Shew_1310 methyl-accepting chemotaxis sensory transducer YP_001501185.1 PFAM: protein of unknown function DUF465; KEGG: saz:Sama_2344 hypothetical protein YP_001501186.1 PFAM: acriflavin resistance protein; KEGG: slo:Shew_1311 acriflavin resistance protein YP_001501187.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: slo:Shew_1312 efflux transporter, RND family, MFP subunit YP_001501188.1 PFAM: regulatory protein TetR; KEGG: slo:Shew_1313 transcriptional regulator, TetR family YP_001501189.1 KEGG: sbm:Shew185_2984 hypothetical protein YP_001501190.1 KEGG: slo:Shew_1316 hypothetical protein YP_001501191.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: pin:Ping_2637 methyltransferase type 12 YP_001501192.1 PFAM: sodium:dicarboxylate symporter; KEGG: vfi:VF0647 proton/sodium-glutamate symport protein YP_001501193.1 PFAM: fatty acid hydroxylase; KEGG: eli:ELI_07660 hypothetical protein YP_001501194.1 KEGG: slo:Shew_1337 hypothetical protein YP_001501195.1 KEGG: shw:Sputw3181_1399 hypothetical protein YP_001501196.1 PFAM: protein of unknown function DUF400; KEGG: slo:Shew_1339 protein of unknown function DUF400 YP_001501197.1 PFAM: FlgN family protein; KEGG: slo:Shew_1340 FlgN family protein YP_001501198.1 PFAM: Anti-sigma-28 factor FlgM family protein; KEGG: slo:Shew_1341 anti-sigma-28 factor, FlgM YP_001501199.1 required for the assembly of the flagellar basal body P-ring YP_001501200.1 PFAM: response regulator receiver; CheW domain protein; KEGG: shw:Sputw3181_1404 putative CheW protein YP_001501201.1 PFAM: MCP methyltransferase CheR-type; KEGG: shn:Shewana3_1320 MCP methyltransferase, CheR-type YP_001501202.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod YP_001501203.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001501204.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_001501205.1 the hook connects flagellar basal body to the flagellar filament YP_001501206.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_001501207.1 makes up the distal portion of the flagellar basal body rod YP_001501208.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001501209.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001501210.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_001501211.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: slo:Shew_1354 flagellar hook-associated protein FlgK YP_001501212.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes. YP_001501213.1 PFAM: flagellin domain protein; KEGG: she:Shewmr4_1273 flagellin domain protein YP_001501214.1 PFAM: flagellin domain protein; KEGG: she:Shewmr4_1273 flagellin domain protein YP_001501215.1 PFAM: flagellar protein FlaG protein; KEGG: shn:Shewana3_1334 flagellar protein FlaG protein YP_001501216.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; KEGG: sfr:Sfri_1175 flagellar hook-associated 2 domain protein YP_001501217.1 KEGG: spc:Sputcn32_2582 hypothetical protein YP_001501218.1 flagellin specific chaperone YP_001501219.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; flagellar regulatory FleQ domain protein; SMART: AAA ATPase; KEGG: slo:Shew_1362 sigma54 specific transcriptional regulator, fis family YP_001501220.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: PAS domain containing protein; KEGG: sbm:Shew185_2939 PAS/PAC sensor signal transduction histidine kinase YP_001501221.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: sfr:Sfri_1180 two component, sigma54 specific, transcriptional regulator, fis family protein YP_001501222.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: sfr:Sfri_1181 flagellar hook-basal body complex subunit FliE YP_001501223.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001501224.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001501225.1 PFAM: flagellar assembly protein FliH; KEGG: sbm:Shew185_2934 flagellar assembly protein FliH YP_001501226.1 involved in type III protein export during flagellum assembly YP_001501227.1 TIGRFAM: flagellar export protein FliJ; KEGG: son:SO_3224 flagellar protein FliJ YP_001501228.1 PFAM: flagellar hook-length control protein; KEGG: slo:Shew_1371 flagellar hook-length control protein YP_001501229.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_001501230.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001501231.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001501232.1 PFAM: flagellar biosynthesis protein FliO; KEGG: slo:Shew_1375 flagellar biosynthesis protein, FliO YP_001501233.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001501234.1 TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ family 3; KEGG: slo:Shew_1377 flagellar biosynthetic protein FliQ YP_001501235.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001501236.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001501237.1 membrane protein involved in the flagellar export apparatus YP_001501238.1 positive regulator of class III flagellar genes YP_001501239.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: saz:Sama_2281 cobyrinic acid a,c-diamide synthase YP_001501240.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001501241.1 PFAM: response regulator receiver; KEGG: slo:Shew_1384 response regulator receiver protein YP_001501242.1 PFAM: Chemotaxis phosphatase CheZ; KEGG: saz:Sama_2278 putative chemotaxis phosphatase, CheZ YP_001501243.1 PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; KEGG: slo:Shew_1386 CheA signal transduction histidine kinase YP_001501244.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001501245.1 KEGG: slo:Shew_1388 hypothetical protein YP_001501246.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: slo:Shew_1389 cobyrinic acid a,c-diamide synthase YP_001501247.1 PFAM: CheW domain protein; KEGG: slo:Shew_1390 CheW protein YP_001501248.1 PFAM: CheW domain protein; KEGG: slo:Shew_1391 CheW protein YP_001501249.1 KEGG: slo:Shew_1392 hypothetical protein YP_001501250.1 KEGG: sbm:Shew185_2909 FlhB domain protein YP_001501251.1 KEGG: son:SO_3198 hypothetical protein YP_001501252.1 PFAM: VacJ family lipoprotein; KEGG: sbl:Sbal_2897 VacJ family lipoprotein YP_001501253.1 PFAM: response regulator receiver; KEGG: slo:Shew_1396 response regulator receiver protein YP_001501254.1 KEGG: sbl:Sbal_2895 amino acid/peptide transporter; TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor type I/II extracellular region; major facilitator superfamily MFS_1 YP_001501255.1 TIGRFAM: transcriptional activator RfaH; PFAM: NGN domain protein; KEGG: slo:Shew_1398 NusG antitermination factor YP_001501256.1 PFAM: polysaccharide export protein; KEGG: slo:Shew_1399 polysaccharide export protein YP_001501257.1 crystal structure of protein from Xanthomonas shows pentameric toroidal structure; physiological function is unknown YP_001501258.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: slo:Shew_1400 lipopolysaccharide biosynthesis protein YP_001501259.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose YP_001501260.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: son:SO_3186 glucose-1-phosphate-thymidylyltransferase YP_001501261.1 PFAM: WxcM domain protein; KEGG: plu:plu4812 WblP protein YP_001501262.1 PFAM: GCN5-related N-acetyltransferase; KEGG: esa:ESA_01180 hypothetical protein YP_001501263.1 KEGG: chu:CHU_2508 hypothetical protein YP_001501264.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: plu:plu4813 WblQ protein YP_001501265.1 KEGG: nph:NP1948A hypothetical protein YP_001501266.1 PFAM: peptidase C26; KEGG: nph:NP1950A sugar metabolism cluster protein (predicted glutamine amidotransferases) YP_001501267.1 KEGG: hha:Hhal_0773 nucleotidyl transferase YP_001501268.1 PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; KEGG: fjo:Fjoh_2238 CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase YP_001501269.1 PFAM: polysaccharide biosynthesis protein; KEGG: fjo:Fjoh_2240 polysaccharide biosynthesis protein YP_001501270.1 PFAM: glycosyl transferase group 1; KEGG: cth:Cthe_1357 glycosyl transferase, group 1 YP_001501271.1 KEGG: ftf:FTF1458c membrane protein/O-antigen protein YP_001501272.1 PFAM: glycosyl transferase family 2; KEGG: esa:ESA_01184 hypothetical protein YP_001501273.1 PFAM: glycosyl transferase family 2; KEGG: cdf:CD2772 putative teichuronic acid biosynthesis glycosyl transferase YP_001501274.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: wbgX; putative glycosyltransferase YP_001501275.1 PFAM: sugar transferase; KEGG: wbgY; putative glycosyltransferase YP_001501276.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: sbl:Sbal_2876 polysaccharide biosynthesis protein CapD YP_001501277.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: sfr:Sfri_2820 beta-lactamase domain protein YP_001501278.1 PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: she:Shewmr4_1330 UDP-glucose 6-dehydrogenase YP_001501279.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: she:Shewmr4_3886 UDP-glucuronate 5'-epimerase YP_001501280.1 KEGG: shw:Sputw3181_1476 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related YP_001501281.1 PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; KEGG: sbl:Sbal_2320 CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase YP_001501282.1 KEGG: shn:Shewana3_2003 glycerol-3-phosphate cytidylyltransferase; TIGRFAM: cytidyltransferase-related domain; glycerol-3-phosphate cytidylyltransferase; PFAM: cytidylyltransferase YP_001501283.1 KEGG: shn:Shewana3_2004 nucleotidyl transferase YP_001501284.1 KEGG: shn:Shewana3_2005 glycosyl transferase, WecB/TagA/CpsF family; TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: sugar transferase; glycosyl transferase WecB/TagA/CpsF YP_001501285.1 PFAM: glycosyl transferase family 2; KEGG: shn:Shewana3_2006 glycosyl transferase, family 2 YP_001501286.1 PFAM: polysaccharide biosynthesis protein; KEGG: shn:Shewana3_2007 polysaccharide biosynthesis protein YP_001501287.1 KEGG: shn:Shewana3_2008 hypothetical protein YP_001501288.1 KEGG: shn:Shewana3_2009 hypothetical protein YP_001501289.1 PFAM: polysaccharide export protein; KEGG: shn:Shewana3_2010 polysaccharide export protein YP_001501290.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: shn:Shewana3_2011 anti-sigma-factor antagonist YP_001501291.1 KEGG: shn:Shewana3_2012 putative anti-sigma regulatory factor, serine/threonine protein kinase YP_001501292.1 PFAM: response regulator receiver; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: shn:Shewana3_2013 response regulator receiver modulated serine phosphatase YP_001501293.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; KEGG: shn:Shewana3_2014 phosphonate ABC transporter, periplasmic phosphonate-binding protein YP_001501294.1 KEGG: shn:Shewana3_2015 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001501295.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: shn:Shewana3_2016 two component, sigma54 specific, transcriptional regulator, fis family YP_001501296.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sfr:Sfri_3709 PHP C-terminal domain protein YP_001501297.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: shn:Shewana3_2793 dTDP-4-dehydrorhamnose reductase YP_001501298.1 KEGG: slo:Shew_1426 hypothetical protein YP_001501299.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: sbl:Sbal_1133 beta-glucosidase YP_001501300.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: slo:Shew_1427 3'(2'),5'-bisphosphate nucleotidase YP_001501301.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_001501302.1 PFAM: protein of unknown function DUF218; KEGG: slo:Shew_1429 protein of unknown function DUF218 YP_001501303.1 KEGG: shm:Shewmr7_2681 hypothetical protein YP_001501304.1 PFAM: protein of unknown function DUF583; KEGG: slo:Shew_1431 protein of unknown function DUF583 YP_001501305.1 TIGRFAM: ferredoxin-type protein NapF; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: shn:Shewana3_2784 ferredoxin-type protein NapF YP_001501306.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: slo:Shew_1433 UDP-glucose 4-epimerase YP_001501307.1 KEGG: sbm:Shew185_1478 UTP-glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase YP_001501308.1 phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin YP_001501309.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_001501310.1 PFAM: sigma-54 factor interaction domain-containing protein; amino acid-binding ACT domain protein; SMART: AAA ATPase; KEGG: slo:Shew_1437 transcriptional regulator, TyrR YP_001501311.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: slo:Shew_1438 fumarylacetoacetate (FAA) hydrolase YP_001501312.1 TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase domain; KEGG: shn:Shewana3_2777 response regulator receiver protein YP_001501313.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: shn:Shewana3_1691 transcriptional regulator, LysR family YP_001501314.1 PFAM: major facilitator superfamily MFS_1; KEGG: slo:Shew_1441 major facilitator superfamily MFS_1 YP_001501315.1 KEGG: slo:Shew_1448 hypothetical protein YP_001501316.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001501317.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_1451 ABC transporter-related protein YP_001501318.1 PFAM: helix-turn-helix- domain containing protein AraC type; HhH-GPD family protein; Ada metal-binding domain protein; AlkA domain protein; KEGG: shn:Shewana3_1420 transcriptional regulator, AraC family YP_001501319.1 KEGG: sdn:Sden_2530 methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding YP_001501320.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: shw:Sputw3181_1513 DEAD/DEAH box helicase domain protein YP_001501321.1 PFAM: Dual specificity protein phosphatase; KEGG: shw:Sputw3181_1514 dual specificity protein phosphatase YP_001501322.1 PFAM: phospholipase D/Transphosphatidylase; KEGG: slo:Shew_1456 phospholipase D/transphosphatidylase YP_001501323.1 PFAM: response regulator receiver; CheW domain protein; KEGG: slo:Shew_1457 response regulator receiver modulated CheW protein YP_001501324.1 involved in the import of serine and threonine coupled with the import of sodium YP_001501325.1 PFAM: oxidoreductase domain protein; KEGG: sbm:Shew185_2813 oxidoreductase domain protein YP_001501326.1 KEGG: slo:Shew_1459 hypothetical protein YP_001501327.1 PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_1442 pseudouridylate synthase YP_001501328.1 PFAM: protein of unknown function DUF479; KEGG: slo:Shew_2339 protein of unknown function DUF479 YP_001501329.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001501330.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001501331.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_001501332.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001501333.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001501334.1 KEGG: slo:Shew_2333 hypothetical protein YP_001501335.1 PFAM: Rhodanese domain protein; KEGG: saz:Sama_2188 rhodanese-like protein YP_001501336.1 TIGRFAM: siroheme synthase; KEGG: sbl:Sbal_2781 siroheme synthase YP_001501337.1 PFAM: YaeQ family protein; KEGG: shw:Sputw3181_1530 YaeQ family protein YP_001501338.1 PFAM: carbon starvation protein CstA; KEGG: slo:Shew_2330 carbon starvation protein CstA YP_001501339.1 unknown function; when overproduced it confers drug-resistance YP_001501340.1 PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; KEGG: shn:Shewana3_2593 signal transduction histidine kinase, LytS YP_001501341.1 KEGG: sfr:Sfri_1783 hypothetical protein YP_001501342.1 PFAM: type IV pilus assembly PilZ; KEGG: shn:Shewana3_2589 type IV pilus assembly PilZ YP_001501343.1 PFAM: phosphate-starvation-inducible E; KEGG: shn:Shewana3_2588 phosphate-starvation-inducible E YP_001501344.1 PFAM: inositol monophosphatase; KEGG: slo:Shew_2321 inositol monophosphatase YP_001501345.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: slo:Shew_2320 RNA methyltransferase, TrmH family, group 1 YP_001501346.1 TIGRFAM: serine O-acetyltransferase; KEGG: she:Shewmr4_1737 serine O-acetyltransferase YP_001501347.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; iron-sulfur cluster assembly transcription factor IscR; PFAM: protein of unknown function UPF0074; KEGG: slo:Shew_2318 transcriptional regulator, BadM/Rrf2 family YP_001501348.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_001501349.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: slo:Shew_2316 FeS cluster assembly scaffold IscU YP_001501350.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; iron-sulfur cluster assembly protein IscA; PFAM: HesB/YadR/YfhF-family protein; KEGG: slo:Shew_2315 iron-sulfur cluster assembly protein IscA YP_001501351.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_001501352.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_001501353.1 TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: slo:Shew_2312 ferredoxin, 2Fe-2S type, ISC system YP_001501354.1 KEGG: mmw:Mmwyl1_3491 transposase YP_001501355.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3340 integrase, catalytic region YP_001501356.1 PFAM: protein of unknown function DUF528; KEGG: slo:Shew_2311 protein of unknown function DUF528 YP_001501357.1 KEGG: saz:Sama_1300 hypothetical protein YP_001501358.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001501359.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: slo:Shew_2244 TonB-dependent receptor YP_001501360.1 KEGG: shm:Shewmr7_2334 transcriptional regulators, TraR/DksA family YP_001501361.1 PFAM: dihydrouridine synthase DuS; KEGG: son:SO_2006 NifR3/Smm1 family protein YP_001501362.1 KEGG: pha:PSHAa1196 hypothetical protein YP_001501363.1 PFAM: protein of unknown function DUF692; Xylose isomerase domain protein TIM barrel; KEGG: slo:Shew_2240 protein of unknown function DUF692 YP_001501364.1 KEGG: slo:Shew_2239 hypothetical protein YP_001501365.1 KEGG: sfr:Sfri_2410 hypothetical protein YP_001501366.1 PFAM: protein of unknown function DUF454; KEGG: slo:Shew_2237 protein of unknown function DUF454 YP_001501367.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001501368.1 KEGG: shn:Shewana3_2446 DNA polymerase III, subunits gamma and tau; TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase YP_001501369.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_2234 conserved hypothetical protein 103 YP_001501370.1 KEGG: pla:Plav_3095 transferase hexapeptide repeat containing protein YP_001501371.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: lpp:lpp2174 hypothetical protein YP_001501373.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: pha:PSHAb0158 putative TonB-dependent receptor with TonB-box YP_001501374.1 PFAM: Kelch repeat-containing protein; KEGG: cpe:CPE0726 hypothetical protein YP_001501375.1 KEGG: vco:VC0395_A1381 neuraminidase YP_001501376.1 KEGG: pha:PSHAb0155 putative hydrolase YP_001501377.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization YP_001501378.1 TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: pha:PSHAb0151 putative sodium-dependent carbohydrate permease YP_001501379.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_001501380.1 PFAM: ROK family protein; KEGG: pha:PSHAb0149 putative N-acetylglucosamine kinase with actin-like ATPase domain/transcriptional regulator (NagC/XylR (ROK) family) YP_001501381.1 TIGRFAM: glucosamine-6-phosphate isomerase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: cps:CPS_1008 glucosamine-6-phosphate isomerase YP_001501382.1 PFAM: dihydrodipicolinate synthetase; KEGG: pha:PSHAb0156 N-acetylneuraminate lyase (aldolase) YP_001501383.1 KEGG: pha:PSHAb0157 putative N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase YP_001501384.1 KEGG: pha:PSHAb0153 hypothetical protein YP_001501385.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001501386.1 molecular chaperone YP_001501387.1 PFAM: Thioredoxin domain; KEGG: slo:Shew_2231 thioredoxin domain protein YP_001501388.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001501389.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001501390.1 PFAM: PfkB domain protein; KEGG: son:SO_2020 inosine-guanosine kinase YP_001501391.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: vvu:VV2_1651 acetyltransferase YP_001501392.1 PFAM: sodium:dicarboxylate symporter; KEGG: sbl:Sbal_2499 sodium:dicarboxylate symporter YP_001501393.1 PFAM: Ig domain protein group 1 domain protein; KEGG: slo:Shew_2226 Ig domain protein, group 1 domain protein YP_001501394.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_001501395.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001501396.1 KEGG: slo:Shew_1623 hypothetical protein YP_001501397.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_001501398.1 KEGG: she:Shewmr4_1725 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001501399.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_001501400.1 PFAM: protein of unknown function UPF0227; KEGG: slo:Shew_1627 protein of unknown function UPF0227 YP_001501401.1 catalyzes the hydrolysis of acylphosphate YP_001501402.1 KEGG: slo:Shew_1629 hypothetical protein YP_001501403.1 KEGG: slo:Shew_1630 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases YP_001501404.1 KEGG: shw:Sputw3181_1854 hypothetical protein YP_001501405.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: slo:Shew_1632 lipoprotein releasing system, transmembrane protein, LolC/E family YP_001501406.1 KEGG: spc:Sputcn32_2155 lipoprotein releasing system, ATP-binding protein; TIGRFAM: lipoprotein releasing system, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase YP_001501407.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: slo:Shew_1634 lipoprotein releasing system, transmembrane protein, LolC/E family YP_001501408.1 KEGG: sfr:Sfri_0576 hypothetical protein YP_001501409.1 KEGG: ppr:PBPRB1356 hypothetical protein YP_001501410.1 KEGG: pha:PSHAa1936 hypothetical protein YP_001501412.1 PFAM: secretion protein HlyD family protein; KEGG: vha:VIBHAR_07032 hypothetical protein YP_001501413.1 KEGG: ppr:PBPRB1428 hypothetical protein YP_001501414.1 PFAM: regulatory protein MarR; KEGG: ppr:PBPRB1427 hypothetical transcriptional regulator YP_001501415.1 PFAM: protein of unknown function DUF991; KEGG: slo:Shew_1489 protein of unknown function DUF991 YP_001501416.1 KEGG: son:SO_2183 hypothetical protein YP_001501417.1 PFAM: Ion transport protein; Ion transport 2 domain protein; KEGG: slo:Shew_1491 ion transport protein YP_001501418.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: she:Shewmr4_1623 MATE efflux family protein YP_001501419.1 KEGG: slo:Shew_1493 hypothetical protein YP_001501420.1 PFAM: protein of unknown function DUF437; KEGG: vvy:VVA0554 hypothetical protein YP_001501421.1 PFAM: regulatory protein TetR; KEGG: vha:VIBHAR_06539 hypothetical protein YP_001501422.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: vvu:VV2_1321 membrane-fusion protein YP_001501423.1 PFAM: acriflavin resistance protein; KEGG: vha:VIBHAR_06541 hypothetical protein YP_001501424.1 PFAM: purine or other phosphorylase family 1; KEGG: vpa:VPA1089 putative 5'-methylthioadenosine/S-adenosylhomocy steine nuclosidase YP_001501426.1 PFAM: Integral membrane protein TerC; KEGG: ppr:PBPRA2002 hypothetical transmembrane transportprotein YP_001501427.1 KEGG: slo:Shew_1496 lipoprotein, putative YP_001501428.1 PFAM: glutathione-dependent formaldehyde-activating GFA; KEGG: shw:Sputw3181_0824 glutathione-dependent formaldehyde-activating, GFA YP_001501429.1 PFAM: UspA domain protein; KEGG: slo:Shew_3100 UspA domain protein YP_001501430.1 PFAM: sodium:dicarboxylate symporter; KEGG: she:Shewmr4_0147 sodium:dicarboxylate symporter YP_001501431.1 PFAM: band 7 protein; KEGG: slo:Shew_1785 band 7 protein YP_001501432.1 PFAM: protein of unknown function DUF107; KEGG: sdn:Sden_2190 protein of unknown function DUF107 YP_001501433.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001501434.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001501435.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001501436.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_001501437.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_001501438.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001501439.1 KEGG: shw:Sputw3181_3319 NADH:ubiquinone oxidoreductase, subunit F YP_001501440.1 KEGG: shw:Sputw3181_3319 NADH:ubiquinone oxidoreductase, subunit F YP_001501441.1 KEGG: shw:Sputw3181_3319 NADH:ubiquinone oxidoreductase, subunit F YP_001501442.1 KEGG: shn:Shewana3_2869 hypothetical protein YP_001501443.1 KEGG: saz:Sama_3567 hypothetical protein YP_001501444.1 PFAM: Arylsulfotransferase; KEGG: ecv:APECO1_3375 arylsulfate sulfotransferase YP_001501445.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001501446.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001501447.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_001501448.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001501449.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001501450.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001501451.1 PFAM: protein of unknown function DUF1538; KEGG: sfr:Sfri_2271 protein of unknown function DUF1538 YP_001501452.1 PFAM: protein of unknown function DUF1538; KEGG: slo:Shew_1498 protein of unknown function DUF1538 YP_001501453.1 KEGG: sfr:Sfri_2273 putative nitrogen regulatory protein P-II YP_001501454.1 PFAM: CBS domain containing protein; KEGG: slo:Shew_1500 putative signal transduction protein with CBS domains YP_001501455.1 PFAM: regulatory protein RecX; KEGG: sfr:Sfri_0228 regulatory protein RecX YP_001501457.1 PFAM: PEBP family protein; KEGG: ajs:Ajs_0693 PEBP family protein YP_001501458.1 KEGG: shw:Sputw3181_2537 glutaredoxin YP_001501459.1 PFAM: peptidase S51 dipeptidase E; KEGG: slo:Shew_1665 peptidase S51, dipeptidase E YP_001501460.1 PFAM: protein of unknown function DUF748; KEGG: slo:Shew_1502 protein of unknown function DUF748 YP_001501461.1 KEGG: slo:Shew_1505 hypothetical protein YP_001501462.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sfr:Sfri_1598 glyoxalase/bleomycin resistance protein/dioxygenase YP_001501463.1 PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: slo:Shew_1507 5-carboxymethyl-2-hydroxymuconate isomerase YP_001501464.1 KEGG: cps:CPS_3225 putative lipoprotein YP_001501465.1 PFAM: FAD dependent oxidoreductase; KEGG: sbm:Shew185_2764 FAD dependent oxidoreductase YP_001501466.1 PFAM: Beta-ketoacyl synthase; KEGG: slo:Shew_2410 beta-ketoacyl synthase YP_001501467.1 KEGG: cps:CPS_3947 hypothetical protein YP_001501468.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: atc:AGR_L_412GM hypothetical protein YP_001501469.1 PFAM: alanine racemase domain protein; KEGG: eca:ECA2038 hypothetical protein YP_001501470.1 PFAM: ornithine cyclodeaminase/mu-crystallin; KEGG: eca:ECA2039 putative ornithine cyclodeaminase YP_001501471.1 PFAM: GCN5-related N-acetyltransferase; KEGG: bce:BC2806 acetyltransferase YP_001501472.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sbl:Sbal_2745 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001501473.1 KEGG: slo:Shew_2308 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region YP_001501474.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3340 integrase, catalytic region YP_001501475.1 KEGG: mmw:Mmwyl1_3491 transposase YP_001501476.1 KEGG: slo:Shew_2307 hypothetical protein YP_001501477.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001501478.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: she:Shewmr4_1427 FolC bifunctional protein YP_001501479.1 PFAM: Sporulation domain protein; KEGG: saz:Sama_2148 sporulation related YP_001501480.1 PFAM: Colicin V production protein; KEGG: sfr:Sfri_1398 colicin V production protein YP_001501481.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001501482.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3562 integrase, catalytic region YP_001501483.1 KEGG: sfr:Sfri_3563 transposase YP_001501485.1 decatenates replicating daughter chromosomes YP_001501486.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: slo:Shew_2295 transcriptional regulator, AraC family YP_001501487.1 KEGG: slo:Shew_2294 hypothetical protein YP_001501488.1 KEGG: sde:Sde_2360 putative alpha-glucosidase YP_001501489.1 PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: sbl:Sbal_0193 methyl-accepting chemotaxis sensory transducer YP_001501490.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: vfi:VFA1086 transcriptional regulators, LysR family YP_001501491.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_001501492.1 TIGRFAM: galactokinase; PFAM: GHMP kinase; GHMP kinase domain protein; KEGG: pha:PSHAa1769 galactokinase YP_001501493.1 KEGG: slo:Shew_2284 hypothetical protein YP_001501494.1 PFAM: alpha/beta hydrolase fold; KEGG: slo:Shew_2270 alpha/beta hydrolase fold YP_001501495.1 PFAM: beta-lactamase domain protein; KEGG: shn:Shewana3_1493 beta-lactamase domain protein YP_001501496.1 PFAM: protein of unknown function DUF1097; KEGG: shn:Shewana3_1498 protein of unknown function DUF1097 YP_001501497.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: slo:Shew_2263 methyl-accepting chemotaxis sensory transducer YP_001501498.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_001501499.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_001501500.1 Involved in cell division; probably involved in intracellular septation YP_001501502.1 KEGG: sbl:Sbal_3888 TonB family protein YP_001501503.1 KEGG: ppd:Ppro_0867 cytochrome c family protein YP_001501504.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sdn:Sden_2449 PHP-like protein YP_001501505.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: slo:Shew_2249 SUA5/YciO/YrdC/YwlC family protein YP_001501506.1 PFAM: chromosome segregation and condensation protein ScpA; KEGG: slo:Shew_2248 chromosome segregation and condensation protein ScpA YP_001501507.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB; KEGG: shw:Sputw3181_1609 putative transcriptional regulator YP_001501508.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: slo:Shew_2246 pseudouridine synthase YP_001501509.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: slo:Shew_2409 short-chain dehydrogenase/reductase SDR YP_001501510.1 KEGG: sbl:Sbal_2693 hypothetical protein YP_001501511.1 SohB; periplasmic protein; member of the peptidase S49 family YP_001501512.1 PFAM: protein of unknown function DUF437; KEGG: sbl:Sbal_2524 uncharacterised conserved protein UCP029143 YP_001501513.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: cps:CPS_0377 ISCps1, transposase YP_001501514.1 KEGG: sdn:Sden_3211 hypothetical protein YP_001501515.1 PFAM: dihydrodipicolinate synthetase; KEGG: vpa:VP1335 probable dihydrodipicolinate synthetase YP_001501516.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: shm:Shewmr7_1537 transcriptional regulator, AraC family YP_001501517.1 KEGG: son:SO_2931 hypothetical protein YP_001501518.1 KEGG: slo:Shew_2404 hypothetical protein YP_001501519.1 PFAM: lipolytic protein G-D-S-L family; KEGG: sfr:Sfri_2568 arylesterase YP_001501520.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_2402 ABC transporter-related protein YP_001501521.1 PFAM: protein of unknown function DUF214; KEGG: shm:Shewmr7_1545 protein of unknown function DUF214 YP_001501522.1 PFAM: NAD-dependent epimerase/dehydratase; domain of unknown function DUF1731; KEGG: sfr:Sfri_2559 hypothetical protein YP_001501523.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_001501524.1 PFAM: protein of unknown function UPF0118; KEGG: slo:Shew_2398 protein of unknown function UPF0118 YP_001501525.1 KEGG: sfr:Sfri_2556 hypothetical protein YP_001501526.1 KEGG: shw:Sputw3181_1625 hypothetical protein YP_001501527.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001501528.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001501529.1 PFAM: protein of unknown function DUF412; KEGG: son:SO_2914 hypothetical protein YP_001501530.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_001501531.1 KEGG: slo:Shew_2390 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL YP_001501532.1 KEGG: slo:Shew_2389 hypothetical protein YP_001501533.1 PFAM: formate/nitrite transporter; CBS domain containing protein; KEGG: shw:Sputw3181_1633 formate/nitrite transporter YP_001501534.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: shw:Sputw3181_1634 transcriptional regulator, LysR family YP_001501535.1 KEGG: dps:DP0461 hypothetical protein YP_001501536.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_001501537.1 PFAM: C4-dicarboxylate anaerobic carrier; KEGG: shn:Shewana3_1557 C4-dicarboxylate anaerobic carrier YP_001501538.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: shw:Sputw3181_1637 C4-dicarboxylate transporter/malic acid transport protein YP_001501539.1 KEGG: sfr:Sfri_2128 O-methyltransferase, putative YP_001501540.1 PFAM: regulatory protein TetR; KEGG: slo:Shew_2383 putative transcriptional regulator, TetR family YP_001501541.1 TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: slo:Shew_2382 cysteine synthase A YP_001501542.1 PFAM: RDD domain containing protein; KEGG: sbl:Sbal_2662 RDD domain containing protein YP_001501543.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: saz:Sama_1511 response regulator receiver protein YP_001501544.1 KEGG: sfr:Sfri_2465 hypothetical protein YP_001501545.1 putative role in sulfur assimilation YP_001501546.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; KEGG: slo:Shew_2379 chromosome segregation protein SMC YP_001501547.1 TIGRFAM: cell division protein ZipA; PFAM: ZipA FtsZ-binding region; KEGG: slo:Shew_2378 cell division protein ZipA YP_001501548.1 KEGG: slo:Shew_2377 DNA ligase, NAD-dependent; TIGRFAM: DNA ligase, NAD-dependent; PFAM: BRCT domain protein; zinc-finger NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase OB-fold; NAD-dependent DNA ligase adenylation; SMART: Helix-hairpin-helix DNA-binding class 1; NAD-dependent DNA ligase YP_001501549.1 KEGG: son:SO_2863 hypothetical protein YP_001501550.1 PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: shn:Shewana3_1571 metal dependent phosphohydrolase YP_001501551.1 KEGG: sfr:Sfri_2458 NAD-dependent epimerase/dehydratase YP_001501552.1 PFAM: DSBA oxidoreductase; KEGG: son:SO_2860 thiol:disulfide interchange protein, DsbA family YP_001501553.1 SMART: protein phosphatase 2C domain protein; KEGG: stt:t4521 hypothetical protein YP_001501554.1 KEGG: slo:Shew_2372 hypothetical protein YP_001501555.1 PFAM: Na+/solute symporter; KEGG: slo:Shew_2371 Na+/solute symporter YP_001501556.1 PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294 nucleotidyltransferase putative; KEGG: slo:Shew_2369 cyclic nucleotide-binding protein YP_001501557.1 PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: sbl:Sbal_2636 exonuclease, RNase T and DNA polymerase III YP_001501558.1 KEGG: slo:Shew_2367 hypothetical protein YP_001501559.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis YP_001501560.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: slo:Shew_2365 transcriptional regulator, GntR family YP_001501561.1 PFAM: aldehyde dehydrogenase; KEGG: slo:Shew_2364 aldehyde dehydrogenase YP_001501562.1 PFAM: proline racemase; KEGG: slo:Shew_2363 proline racemase YP_001501563.1 KEGG: slo:Shew_2362 dihydrodipicolinate synthase YP_001501564.1 PFAM: proline racemase; KEGG: slo:Shew_2361 proline racemase YP_001501565.1 PFAM: FAD dependent oxidoreductase; KEGG: slo:Shew_2360 D-amino-acid dehydrogenase YP_001501566.1 PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: ilo:IL1385 predicted NAD/FAD-binding protein YP_001501567.1 KEGG: ana:alr4631 unknown protein YP_001501568.1 KEGG: pin:Ping_1766 hypothetical protein YP_001501569.1 PFAM: amino acid permease-associated region; Amino acid transporter transmembrane; KEGG: lpn:lpg0281 amino acid transporter YP_001501570.1 PFAM: peptidase M24; peptidase M24B X-Pro dipeptidase/aminopeptidase domain protein; KEGG: slo:Shew_2358 peptidase M24 YP_001501571.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_001501572.1 KEGG: vvy:VV3174 transposase and inactivated derivative YP_001501573.1 KEGG: son:SO_4210 hypothetical protein YP_001501574.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: aha:AHA_0961 hypothetical protein YP_001501575.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: aha:AHA_0959 nucleoside permease YP_001501576.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_001501577.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: aha:AHA_0957 HTH-type transcriptional regulator XapR YP_001501578.1 KEGG: shm:Shewmr7_1590 hypothetical protein YP_001501579.1 KEGG: slo:Shew_2354 hypothetical protein YP_001501580.1 TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2 transporter protein CorA family protein; KEGG: shm:Shewmr7_1720 magnesium and cobalt transport protein CorA YP_001501581.1 KEGG: slo:Shew_2352 hypothetical protein YP_001501582.1 KEGG: shn:Shewana3_1721 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region YP_001501583.1 KEGG: vfi:VFA0845 hypothetical protein YP_001501584.1 PFAM: beta-lactamase domain protein; KEGG: vvy:VVA1356 alkyl sulfatase YP_001501585.1 PFAM: regulatory protein LysR; KEGG: ppr:PBPRB0854 hypothetical transcriptional regulator YP_001501586.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: csa:Csal_3004 membrane protein involved in aromatic hydrocarbon degradation YP_001501587.1 PFAM: acriflavin resistance protein; KEGG: pha:PSHAb0438 putative metabolite exporter, AcrB/D/F family YP_001501588.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ilo:IL0466 RND efflux system membrane fusion protein YP_001501589.1 KEGG: vfi:VFA0845 hypothetical protein YP_001501590.1 PFAM: Radical SAM domain protein; KEGG: vfi:VFA0208 arylsulfatase regulator (Fe-S oxidoreductase) YP_001501591.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: sfu:Sfum_1664 two component transcriptional regulator, LuxR family YP_001501592.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: sat:SYN_01954 signal transduction histidine kinase YP_001501593.1 PFAM: sulfatase; KEGG: rle:RL1911 putative arylsulfatase YP_001501594.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: pat:Patl_1662 ATPase associated with various cellular activities, AAA_3 YP_001501595.1 KEGG: vpa:VPA0686 hypothetical protein YP_001501597.1 PFAM: von Willebrand factor type A; KEGG: cps:CPS_2991 von Willebrand factor type A domain protein YP_001501598.1 KEGG: vfi:VFA0904 hypothetical protein YP_001501599.1 KEGG: pfl:PFL_2844 hypothetical protein YP_001501601.1 PFAM: type I phosphodiesterase/nucleotide pyrophosphatase; KEGG: vvy:VVA0670 hypothetical protein YP_001501602.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase alpha subunit; KEGG: son:SO_1944 hypothetical protein YP_001501603.1 PFAM: ATP-binding region ATPase domain protein; KEGG: sbl:Sbal_2502 integral membrane sensor signal transduction histidine kinase YP_001501604.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: slo:Shew_2348 two component transcriptional regulator, winged helix family YP_001501605.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; KEGG: saz:Sama_1543 putative phosphonate ABC transporter, periplasmic phosphonate-binding protein YP_001501606.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_2346 ABC transporter-related protein YP_001501607.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_2345 binding-protein-dependent transport systems inner membrane component YP_001501608.1 KEGG: slo:Shew_2344 hypothetical protein YP_001501609.1 TIGRFAM: Phasin family protein; KEGG: ppr:PBPRB1839 hypothetical protein YP_001501610.1 TIGRFAM: poly(R)-hydroxyalkanoic acid synthase, class I; PFAM: alpha/beta hydrolase fold; Poly-beta-hydroxybutyrate polymerase domain protein; KEGG: ppr:PBPRB1838 polyhydroxyalkanoic acid synthase YP_001501611.1 PFAM: MaoC domain protein dehydratase; KEGG: aha:AHA_2422 enoyl-CoA hydratase YP_001501612.1 KEGG: sdn:Sden_1364 hypothetical protein YP_001501613.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: slo:Shew_2342 integral membrane sensor signal transduction histidine kinase YP_001501614.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: slo:Shew_2341 two component, sigma54 specific, transcriptional regulator, fis family YP_001501615.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: slo:Shew_1462 lysine exporter protein (LysE/YggA) YP_001501616.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001501617.1 KEGG: shw:Sputw3181_1715 hypothetical protein YP_001501618.1 KEGG: sfr:Sfri_1544 lysophospholipase-like protein YP_001501619.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: slo:Shew_1467 diguanylate cyclase YP_001501620.1 KEGG: slo:Shew_2961 hypothetical protein YP_001501621.1 PFAM: sulfatase; KEGG: shn:Shewana3_2428 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase YP_001501622.1 PFAM: protein of unknown function DUF1414; KEGG: shn:Shewana3_2427 protein of unknown function DUF1414 YP_001501623.1 PFAM: 37kDa nucleoid-associated protein; KEGG: slo:Shew_1472 37 kDa nucleoid-associated protein YP_001501624.1 KEGG: slo:Shew_1473 hypothetical protein YP_001501625.1 PFAM: peptidase M23B; KEGG: slo:Shew_1474 peptidase M23B YP_001501626.1 KEGG: slo:Shew_1636 hypothetical protein YP_001501627.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG: sbm:Shew185_1667 DNA internalization-related competence protein ComEC/Rec2 YP_001501628.1 KEGG: sbm:Shew185_1668 lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; TIGRFAM: lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001501629.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001501630.1 PFAM: protein of unknown function DUF343; KEGG: son:SO_2800 hypothetical protein YP_001501631.1 PFAM: Peptidase M11 gametolysin; KEGG: slo:Shew_1642 peptidase M11, gametolysin YP_001501632.1 KEGG: slo:Shew_1643 hypothetical protein YP_001501633.1 PFAM: DSBA oxidoreductase; KEGG: slo:Shew_1644 DsbA oxidoreductase YP_001501634.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: slo:Shew_1645 sigma54 specific transcriptional regulator, fis family YP_001501635.1 KEGG: vpa:VP1135 hypothetical protein YP_001501636.1 KEGG: slo:Shew_0958 hypothetical protein YP_001501637.1 PFAM: acriflavin resistance protein; KEGG: slo:Shew_1647 acriflavin resistance protein YP_001501638.1 PFAM: acriflavin resistance protein; KEGG: slo:Shew_1648 acriflavin resistance protein YP_001501639.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_1649 efflux transporter, RND family, MFP subunit YP_001501640.1 KEGG: shw:Sputw3181_1734 citrate synthase I YP_001501641.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001501642.1 TIGRFAM: Succinate dehydrogenase cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: slo:Shew_1651 succinate dehydrogenase, cytochrome b subunit YP_001501643.1 TIGRFAM: Succinate dehydrogenase hydrophobic membrane anchor; KEGG: shw:Sputw3181_1736 conserved hypothetical succinate dehydrogenase, hydrophobic subunit YP_001501644.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001501645.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001501646.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001501647.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: slo:Shew_1656 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase YP_001501648.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001501649.1 TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: sdn:Sden_2180 succinyl-CoA synthetase, alpha subunit YP_001501650.1 KEGG: ppr:PBPRA2342 hypothetical protein YP_001501651.1 PFAM: Auxin Efflux Carrier; KEGG: sfr:Sfri_2339 auxin efflux carrier YP_001501652.1 PFAM: ferredoxin-dependent glutamate synthase; KEGG: slo:Shew_1659 ferredoxin-dependent glutamate synthase YP_001501653.1 PFAM: GCN5-related N-acetyltransferase; KEGG: slo:Shew_1660 GCN5-related N-acetyltransferase YP_001501654.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_001501655.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_001501656.1 KEGG: son:SO_1939 hypothetical protein YP_001501657.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001501658.1 TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: sdn:Sden_1657 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_001501659.1 KEGG: shn:Shewana3_2519 biotin synthase; TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_001501660.1 PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: sbm:Shew185_1752 8-amino-7-oxononanoate synthase YP_001501661.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: she:Shewmr4_2357 biotin biosynthesis protein BioC YP_001501662.1 KEGG: shm:Shewmr7_2428 dethiobiotin synthase; TIGRFAM: dethiobiotin synthase; PFAM: Cobyrinic acid ac-diamide synthase YP_001501663.1 putative metalloprotease YP_001501664.1 KEGG: slo:Shew_1724 cytochrome c3 YP_001501665.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: sfr:Sfri_1505 molybdopterin oxidoreductase YP_001501666.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sfr:Sfri_1506 uroporphyrin-III C-methyltransferase YP_001501667.1 PFAM: glycosyl transferase family 3; KEGG: sfr:Sfri_1507 glycosyl transferase, family 3 YP_001501668.1 PFAM: ANTAR domain protein; KEGG: sfr:Sfri_1508 response regulator receiver and ANTAR domain protein YP_001501669.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: sfr:Sfri_1509 nitrite reductase (NAD(P)H), large subunit YP_001501670.1 TIGRFAM: nitrite reductase [NAD(P)H], small subunit; PFAM: Rieske [2Fe-2S] domain protein; KEGG: sfr:Sfri_1510 nitrite reductase (NAD(P)H), small subunit YP_001501671.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfr:Sfri_1511 nitrite transporter YP_001501672.1 SMART: tyrosine protein kinase; protein phosphatase 2C domain protein; serine/threonine protein kinase; KEGG: sfr:Sfri_1512 serine/threonine protein kinase YP_001501673.1 PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sbl:Sbal_1794 tetratricopeptide TPR_2 repeat protein YP_001501674.1 PFAM: Curlin associated repeat protein; KEGG: slo:Shew_1725 curlin associated repeat protein YP_001501675.1 PFAM: regulatory protein LuxR; KEGG: slo:Shew_1726 transcriptional regulator, LuxR family YP_001501676.1 KEGG: slo:Shew_1727 hypothetical protein YP_001501677.1 KEGG: slo:Shew_1728 curli production assembly/transport component CsgF precursor YP_001501678.1 PFAM: Curli production assembly/transport component CsgG; KEGG: slo:Shew_1729 curli production assembly/transport component CsgG YP_001501681.1 PFAM: regulatory protein TetR; KEGG: tfu:Tfu_2816 hypothetical protein YP_001501682.1 PFAM: histidine triad (HIT) protein; KEGG: shn:Shewana3_2507 histidine triad (HIT) protein YP_001501683.1 PFAM: thioesterase superfamily protein; KEGG: sbm:Shew185_1791 thioesterase superfamily protein YP_001501684.1 PFAM: thioesterase superfamily protein; KEGG: shn:Shewana3_2505 thioesterase superfamily protein YP_001501685.1 PFAM: protein of unknown function DUF1425; KEGG: slo:Shew_1734 protein of unknown function DUF1425 YP_001501686.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: slo:Shew_1735 TonB-dependent receptor YP_001501687.1 KEGG: sfr:Sfri_1527 hypothetical protein YP_001501688.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: sbl:Sbal_1804 nicotinamide mononucleotide transporter PnuC YP_001501689.1 PFAM: Choline/ethanolamine kinase; aminoglycoside phosphotransferase; KEGG: slo:Shew_1738 aminoglycoside phosphotransferase YP_001501690.1 PFAM: DoxX family protein; KEGG: shn:Shewana3_2495 DoxX family protein YP_001501691.1 PFAM: nitroreductase; KEGG: spc:Sputcn32_1665 nitroreductase YP_001501692.1 KEGG: slo:Shew_1744 GCN5-related N-acetyltransferase YP_001501693.1 KEGG: sbl:Sbal_1813 hypothetical protein YP_001501694.1 KEGG: slo:Shew_1747 hypothetical protein YP_001501695.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: saz:Sama_1468 putative macrolide efflux ABC transporter, ATP-binding protein YP_001501696.1 KEGG: saz:Sama_1469 multidrug resistance efflux pump-like protein YP_001501697.1 KEGG: saz:Sama_1470 membrane-fusion protein YP_001501698.1 KEGG: saz:Sama_1471 membrane-fusion protein YP_001501699.1 PFAM: protein of unknown function DUF214; KEGG: saz:Sama_1472 ABC transporter permease protein YP_001501700.1 PFAM: Ion transport 2 domain protein; KEGG: ppr:PBPRA1561 hypothetical protein YP_001501701.1 PFAM: protein of unknown function UPF0118; KEGG: ppr:PBPRA1562 hypothetical protein YP_001501702.1 KEGG: spc:Sputcn32_1619 hypothetical protein YP_001501703.1 KEGG: sbm:Shew185_1809 hypothetical protein YP_001501704.1 KEGG: sbl:Sbal_1818 hypothetical protein YP_001501705.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_2168 uncharacterized conserved protein UCP025560 YP_001501706.1 KEGG: shn:Shewana3_1844 hypothetical protein YP_001501707.1 KEGG: sbl:Sbal_2434 hypothetical protein YP_001501708.1 KEGG: sco:SCO7159 integral membrane protein YP_001501709.1 PFAM: Aldose 1-epimerase; KEGG: sbm:Shew185_1722 aldose 1-epimerase YP_001501710.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: sfr:Sfri_2744 acyl-CoA dehydrogenase domain protein YP_001501711.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_001501712.1 PFAM: protein of unknown function DUF938; Methyltransferase type 12; KEGG: slo:Shew_2163 protein of unknown function DUF938 YP_001501713.1 KEGG: pin:Ping_2410 hypothetical protein YP_001501714.1 KEGG: mmw:Mmwyl1_1485 putative transcriptional regulator, Fis family protein YP_001501715.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: slo:Shew_2161 peptidyl-dipeptidase DCP YP_001501716.1 KEGG: ppr:PBPRB1968 hypothetical protein YP_001501717.1 PFAM: helix-turn-helix domain protein YP_001501718.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; KEGG: slo:Shew_2159 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor YP_001501719.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: slo:Shew_3322 RarD protein, DMT superfamily transporter YP_001501720.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: swi:Swit_3314 TonB-dependent receptor YP_001501721.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific YP_001501722.1 KEGG: sbm:Shew185_2658 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_001501723.1 PFAM: protein of unknown function DUF482; KEGG: sfr:Sfri_2329 protein of unknown function DUF482 YP_001501726.1 KEGG: saz:Sama_2872 hypothetical protein YP_001501727.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sbl:Sbal_2618 lysine exporter protein (LysE/YggA) YP_001501728.1 KEGG: spc:Sputcn32_0179 hypothetical protein YP_001501729.1 PFAM: protein of unknown function DUF87; KEGG: mca:MCA1687 hypothetical protein YP_001501730.1 KEGG: sbm:Shew185_2659 ATP-dependent endonuclease of the OLD family YP_001501731.1 KEGG: shw:Sputw3181_2355 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001501732.1 PFAM: homogentisate 12-dioxygenase; KEGG: sfr:Sfri_2326 homogentisate 1,2-dioxygenase YP_001501733.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_2153 transcriptional regulator, LysR family YP_001501734.1 KEGG: slo:Shew_2151 hypothetical protein YP_001501735.1 PFAM: Di-haem cytochrome c peroxidase; KEGG: shm:Shewmr7_2292 cytochrome-c peroxidase YP_001501736.1 KEGG: slo:Shew_2150 integral membrane protein TerC YP_001501737.1 KEGG: slo:Shew_2149 conserved hypothetical ABC transporter protein YP_001501738.1 PFAM: alpha/beta hydrolase fold; KEGG: slo:Shew_3018 alpha/beta hydrolase fold YP_001501739.1 PFAM: protein of unknown function DUF307; KEGG: son:SO_1977 hypothetical protein YP_001501740.1 KEGG: son:SO_1978 hypothetical protein YP_001501741.1 KEGG: slo:Shew_2147 hypothetical protein YP_001501742.1 KEGG: shn:Shewana3_2467 hypothetical protein YP_001501743.1 KEGG: slo:Shew_2145 MscS mechanosensitive ion channel YP_001501745.1 e14 prophage; cell death peptidase; inhibitor of T4 late gene expression; late inhibitor of T4 YP_001501746.1 KEGG: aba:Acid345_3545 hypothetical protein YP_001501748.1 PFAM: helix-turn-helix domain protein; KEGG: sfr:Sfri_3420 transcriptional regulator, XRE family protein YP_001501749.1 KEGG: sbm:Shew185_4272 hypothetical protein YP_001501750.1 PFAM: helicase domain protein; type III restriction protein res subunit; KEGG: sbm:Shew185_4273 type III restriction protein res subunit YP_001501751.1 KEGG: shn:Shewana3_1253 hypothetical protein YP_001501754.1 PFAM: integrase family protein; KEGG: vch:VC0183 hypothetical protein YP_001501756.1 PFAM: integrase family protein; KEGG: spc:Sputcn32_0163 hypothetical protein YP_001501757.1 PFAM: MscS Mechanosensitive ion channel; KEGG: saz:Sama_1578 small-conductance mechanosensitive channel YP_001501758.1 PFAM: response regulator receiver; CheW domain protein; KEGG: shn:Shewana3_2462 response regulator receiver modulated CheW protein YP_001501759.1 KEGG: sbl:Sbal_2593 hypothetical protein YP_001501760.1 KEGG: sdn:Sden_2142 hypothetical protein YP_001501761.1 TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: she:Shewmr4_2269 lytic murein transglycosylase YP_001501762.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: slo:Shew_2139 peptidylprolyl isomerase, FKBP-type YP_001501763.1 KEGG: slo:Shew_2138 hypothetical protein YP_001501764.1 PFAM: phospholipase/Carboxylesterase; KEGG: sdn:Sden_2138 carboxylesterase YP_001501765.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_001501766.1 PFAM: heat shock protein Hsp20; KEGG: slo:Shew_2134 heat shock protein HSP20 YP_001501767.1 TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: sdn:Sden_2123 acetolactate synthase, small subunit YP_001501768.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: slo:Shew_1776 acetolactate synthase, large subunit, biosynthetic type YP_001501769.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: slo:Shew_1777 drug resistance transporter, Bcr/CflA subfamily YP_001501770.1 KEGG: slo:Shew_1571 hypothetical protein YP_001501771.1 PFAM: protein of unknown function DUF34; KEGG: shw:Sputw3181_1787 protein of unknown function DUF34 YP_001501772.1 KEGG: mmw:Mmwyl1_3491 transposase YP_001501773.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3340 integrase, catalytic region YP_001501774.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001501775.1 KEGG: slo:Shew_1574 ATP-binding protein, Mrp/Nbp35 family YP_001501776.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_001501777.1 KEGG: sbm:Shew185_2455 deoxycytidine triphosphate deaminase YP_001501778.1 PFAM: aminotransferase class IV; KEGG: shw:Sputw3181_1793 aminotransferase, class IV YP_001501779.1 PFAM: aminodeoxychorismate lyase; KEGG: slo:Shew_1578 aminodeoxychorismate lyase YP_001501780.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001501781.1 TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: slo:Shew_1580 DNA polymerase III, delta prime subunit YP_001501782.1 KEGG: shw:Sputw3181_1797 type IV pilus biogenesis protein PilZ YP_001501783.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: shn:Shewana3_1769 hydrolase, TatD family YP_001501784.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_001501785.1 PFAM: nucleoside recognition domain protein; KEGG: slo:Shew_1584 nucleoside recognition domain protein YP_001501786.1 PFAM: Mammalian cell entry related domain protein; KEGG: she:Shewmr4_1667 mammalian cell entry related domain protein YP_001501787.1 PFAM: Paraquat-inducible protein A; KEGG: shw:Sputw3181_1802 paraquat-inducible protein A YP_001501788.1 PFAM: Paraquat-inducible protein A; KEGG: shm:Shewmr7_1744 paraquat-inducible protein A YP_001501789.1 PFAM: YebG family protein; KEGG: slo:Shew_1799 YebG family protein YP_001501790.1 PFAM: GAF domain protein; KEGG: shw:Sputw3181_1805 putative GAF sensor protein YP_001501791.1 affects solute and DNA transport through an unknown mechanism YP_001501792.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_001501793.1 TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: slo:Shew_1803 aminopeptidase N YP_001501794.1 KEGG: slo:Shew_1804 hypothetical protein YP_001501795.1 PFAM: protein of unknown function DUF1302; KEGG: slo:Shew_1805 protein of unknown function DUF1302 YP_001501796.1 PFAM: protein of unknown function DUF1329; KEGG: slo:Shew_1806 protein of unknown function DUF1329 YP_001501797.1 KEGG: sfr:Sfri_2223 BNR repeat protein YP_001501798.1 PFAM: Patched family protein; KEGG: slo:Shew_1808 hypothetical protein YP_001501799.1 PFAM: NAD-glutamate dehydrogenase; KEGG: slo:Shew_1809 NAD-glutamate dehydrogenase YP_001501800.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001501801.1 PFAM: protein of unknown function DUF1379; KEGG: slo:Shew_1811 protein of unknown function DUF1379 YP_001501802.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: shm:Shewmr7_2838 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001501803.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_001501804.1 PFAM: glutaredoxin 2; KEGG: son:SO_1852 hypothetical protein YP_001501805.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_001501806.1 KEGG: shn:Shewana3_1604 hypothetical protein YP_001501807.1 PFAM: ribosome modulation factor; KEGG: slo:Shew_1816 ribosome modulation factor YP_001501808.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001501809.1 PFAM: peptidase S16 lon domain protein; KEGG: son:SO_1857 hypothetical ATP-dependent protease YP_001501810.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_001501811.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001501812.1 KEGG: slo:Shew_1826 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001501813.1 KEGG: son:SO_4159 hypothetical protein YP_001501814.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: slo:Shew_1828 peptidoglycan-binding domain 1 protein YP_001501815.1 PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: shw:Sputw3181_2115 protein of unknown function DUF882 YP_001501816.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001501817.1 PFAM: SpoVR family protein; KEGG: slo:Shew_1831 SpoVR family protein YP_001501818.1 PFAM: protein of unknown function DUF444; KEGG: slo:Shew_1832 protein of unknown function DUF444 YP_001501819.1 PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: slo:Shew_1833 putative serine protein kinase, PrkA YP_001501820.1 PFAM: manganese and iron superoxide dismutase; KEGG: spc:Sputcn32_1687 superoxide dismutase YP_001501821.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: slo:Shew_1835 glutaredoxin-like protein YP_001501822.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: slo:Shew_1836 uracil-xanthine permease YP_001501823.1 KEGG: slo:Shew_1837 hypothetical protein YP_001501824.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_001501825.1 KEGG: sbl:Sbal_1787 hypothetical protein YP_001501826.1 KEGG: shm:Shewmr7_2421 hypothetical protein YP_001501827.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: sbm:Shew185_1782 arsenate reductase YP_001501828.1 PFAM: peptidase M48 Ste24p; Tetratricopeptide TPR_2 repeat protein; KEGG: sbm:Shew185_1783 peptidase M48 Ste24p YP_001501829.1 PFAM: SirA family protein; KEGG: sdn:Sden_1648 hypothetical protein YP_001501830.1 PFAM: protein of unknown function UPF0118; KEGG: slo:Shew_1843 protein of unknown function UPF0118 YP_001501831.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001501832.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: slo:Shew_1845 lysine exporter protein (LysE/YggA) YP_001501833.1 KEGG: sfr:Sfri_3563 transposase YP_001501834.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3562 integrase, catalytic region YP_001501835.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: son:SO_1877 bacterioferritin comigratory protein YP_001501836.1 PFAM: amino acid-binding ACT domain protein; KEGG: slo:Shew_1847 amino acid-binding ACT domain protein YP_001501837.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001501838.1 PFAM: NlpBDapX family lipoprotein; KEGG: slo:Shew_1849 NlpBDapX family lipoprotein YP_001501839.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_1851 efflux transporter, RND family, MFP subunit YP_001501840.1 PFAM: acriflavin resistance protein; KEGG: slo:Shew_1852 acriflavin resistance protein YP_001501841.1 KEGG: son:SO_2479 hypothetical protein YP_001501842.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001501843.1 PFAM: carbonic anhydrase; KEGG: slo:Shew_1859 carbonate dehydratase YP_001501844.1 PFAM: alpha/beta hydrolase fold; KEGG: shm:Shewmr7_2123 alpha/beta hydrolase fold YP_001501845.1 PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; KEGG: slo:Shew_1861 peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysin YP_001501846.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001501847.1 PFAM: arsenate reductase and related; KEGG: sfr:Sfri_1766 hypothetical protein YP_001501848.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_001501849.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: son:SO_2237 phosphotransferase system, enzyme I YP_001501850.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: sbm:Shew185_2349 phosphotransferase system, phosphocarrier protein HPr YP_001501851.1 KEGG: slo:Shew_1867 hypothetical protein YP_001501852.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; Cache type 2 domain protein; KEGG: slo:Shew_1868 methyl-accepting chemotaxis sensory transducer YP_001501853.1 KEGG: shn:Shewana3_2253 hypothetical protein YP_001501854.1 KEGG: ppr:PBPRB1229 putative DNA polymerase III; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease YP_001501855.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji jmjC domain protein; KEGG: sbl:Sbal_2354 cupin 4 family protein YP_001501856.1 KEGG: rme:Rmet_1758 hypothetical protein YP_001501857.1 KEGG: vfi:VF0656 transcription elongation factor YP_001501859.1 PFAM: helix-turn-helix domain protein; KEGG: sbm:Shew185_4294 transcriptional regulator, XRE family YP_001501860.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001501861.1 PFAM: Fmu (Sun) domain protein; KEGG: son:SO_2215 sun protein, putative YP_001501862.1 PFAM: sulfatase; type I phosphodiesterase/nucleotide pyrophosphatase; KEGG: lpn:lpg2758 hypothetical protein YP_001501863.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: pca:Pcar_1075 hypothetical protein YP_001501864.1 KEGG: vvy:VV3211 transposase and inactivated derivative YP_001501865.1 PFAM: peptidase A24A prepilin type IV; KEGG: pol:Bpro_2546 peptidase A24A, prepilin type IV YP_001501866.1 SMART: AAA ATPase; KEGG: ppr:PBPRB0612 hypothetical protein YP_001501867.1 PFAM: SAF domain protein; KEGG: vvu:VV1_1748 flp pilus assembly protein CpaB YP_001501868.1 PFAM: type II and III secretion system protein; transport-associated; KEGG: vvy:VV2660 flp pilus assembly protein, secretin CpaC YP_001501870.1 KEGG: ppr:PBPRB0607 hypothetical protein YP_001501871.1 PFAM: TadE family protein; KEGG: ppr:PBPRB0606 hypothetical protein YP_001501872.1 PFAM: TadE family protein; KEGG: ppr:PBPRB0605 hypothetical protein YP_001501873.1 KEGG: vvy:VV2654 flp pilus assembly protein, ATPase CpaE YP_001501874.1 PFAM: type II secretion system protein E; KEGG: ppr:PBPRB0603 putative pilus assembly protein YP_001501875.1 PFAM: type II secretion system protein; KEGG: vpa:VP2411 putative tight adherence TadB-related transmembrane protein YP_001501876.1 PFAM: type II secretion system protein; KEGG: ppr:PBPRB0601 hypothetical putative tight adherence TadC-related transmembrane protein YP_001501877.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: ppr:PBPRB0600 hypothetical protein YP_001501878.1 PFAM: hydrogenase expression/synthesis HypA; KEGG: shw:Sputw3181_2177 hydrogenase nickel insertion protein HypA YP_001501879.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: slo:Shew_1756 hydrogenase expression/formation protein HypE YP_001501880.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: slo:Shew_1757 hydrogenase expression/formation protein HypD YP_001501881.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: saz:Sama_1672 hydrogenase assembly chaperone HypC/HupF YP_001501882.1 TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: shw:Sputw3181_2173 hydrogenase accessory protein HypB YP_001501883.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC domain; zinc finger HypF domain protein; KEGG: slo:Shew_1760 (NiFe) hydrogenase maturation protein HypF YP_001501884.1 KEGG: slo:Shew_1761 hypothetical protein YP_001501885.1 TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; PFAM: peptidase M52 hydrogen uptake protein; KEGG: shw:Sputw3181_1921 hydrogenase expression/formation protein YP_001501886.1 TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: slo:Shew_1763 Ni/Fe-hydrogenase, b-type cytochrome subunit YP_001501887.1 PFAM: nickel-dependent hydrogenase large subunit; KEGG: slo:Shew_1764 nickel-dependent hydrogenase, large subunit YP_001501888.1 KEGG: slo:Shew_1765 hydrogenase (NiFe) small subunit HydA; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Nickel-iron dehydrogenase small subunit domain protein YP_001501889.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001501890.1 KEGG: sdn:Sden_1957 hypothetical protein YP_001501891.1 PFAM: NUDIX hydrolase; KEGG: slo:Shew_1902 NUDIX hydrolase YP_001501892.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: shw:Sputw3181_2219 para-aminobenzoate synthase, subunit I YP_001501893.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: slo:Shew_1904 hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit YP_001501894.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: slo:Shew_1905 peptidase S9, prolyl oligopeptidase active site domain protein YP_001501895.1 KEGG: shw:Sputw3181_3605 methylation site containing protein YP_001501896.1 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates YP_001501897.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sfr:Sfri_3138 transcriptional regulator, LysR family protein YP_001501898.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_001501899.1 PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: slo:Shew_1910 iron-containing alcohol dehydrogenase YP_001501900.1 PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: slo:Shew_1911 multiple antibiotic resistance (MarC)-related protein YP_001501901.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_001501902.1 KEGG: son:SO_2484 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region YP_001501903.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001501904.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001501905.1 KEGG: shm:Shewmr7_1938 hypothetical protein YP_001501906.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001501907.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: slo:Shew_1918 CopG domain protein DNA-binding domain protein YP_001501908.1 KEGG: son:SO_2332 hypothetical protein YP_001501909.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: sbl:Sbal_4513 hypothetical protein YP_001501910.1 negative modulator of the initiation of chromosome replication YP_001501911.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001501912.1 KEGG: sun:SUN_2117 hypothetical protein YP_001501913.1 KEGG: neu:NE2100 hypothetical protein YP_001501914.1 PFAM: Domain of unknown function DUF1863; KEGG: shm:Shewmr7_1038 hypothetical protein YP_001501915.1 KEGG: cbe:Cbei_2806 hypothetical protein YP_001501916.1 KEGG: sbo:SBO_1384 hypothetical protein YP_001501917.1 PFAM: ferredoxin; KEGG: slo:Shew_1944 ferredoxin YP_001501918.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_001501919.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001501920.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sfr:Sfri_2132 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_001501921.1 Involved in ubiquinone biosynthesis YP_001501922.1 KEGG: sfr:Sfri_2130 DNA gyrase, A subunit; TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller YP_001501923.1 PFAM: beta-lactamase; KEGG: slo:Shew_1968 beta-lactamase YP_001501924.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001501925.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001501926.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001501927.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001501928.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001501929.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001501930.1 PFAM: protein of unknown function DUF1049; KEGG: slo:Shew_1956 protein of unknown function DUF1049 YP_001501931.1 KEGG: slo:Shew_1957 hypothetical protein YP_001501932.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001501933.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sfr:Sfri_2118 short-chain dehydrogenase/reductase SDR YP_001501934.1 KEGG: slo:Shew_1960 hypothetical protein YP_001501935.1 TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2 transporter protein CorA family protein; KEGG: shm:Shewmr7_1720 magnesium and cobalt transport protein CorA YP_001501936.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: she:Shewmr4_1931 acyl-CoA dehydrogenase domain protein YP_001501937.1 KEGG: slo:Shew_1962 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13 D-Ala-D-Ala carboxypeptidase C YP_001501938.1 KEGG: sbl:Sbal_2079 hypothetical protein YP_001501939.1 PFAM: Domain of unknown function DUF1904; KEGG: slo:Shew_1964 hypothetical protein YP_001501940.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_001501941.1 PFAM: DTW domain containing protein; KEGG: shw:Sputw3181_1985 DTW domain containing protein YP_001501943.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: slo:Shew_1969 two component transcriptional regulator, LuxR family YP_001501944.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: slo:Shew_1970 histidine kinase YP_001501945.1 PFAM: ApbE family lipoprotein; KEGG: slo:Shew_1971 ApbE family lipoprotein YP_001501946.1 PFAM: FMN-binding domain protein; KEGG: slo:Shew_1972 FMN-binding domain protein YP_001501947.1 PFAM: porin Gram-negative type; KEGG: slo:Shew_1973 porin, gram-negative type YP_001501948.1 PFAM: pseudouridine synthase; KEGG: asa:ASA_2900 ribosomal large subunit pseudouridine synthase A YP_001501949.1 PFAM: integrase family protein; KEGG: sbm:Shew185_2263 phage integrase family protein YP_001501950.1 KEGG: sbm:Shew185_2262 hypothetical protein YP_001501951.1 PFAM: protein of unknown function DUF227; SMART: CHK kinase-like; KEGG: slo:Shew_2009 hypothetical protein YP_001501952.1 KEGG: vpa:VPA1278 hypothetical protein YP_001501953.1 KEGG: pha:PSHAb0058 putative orphan protein YP_001501954.1 KEGG: pat:Patl_4270 putative Zn-dependent aminopeptidase YP_001501955.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: vfi:VF1658 short chain dehydrogenase YP_001501956.1 TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; protein of unknown function DUF785; RimK domain protein ATP-grasp; KEGG: fjo:Fjoh_2582 alpha-L-glutamate ligase, RimK family YP_001501957.1 KEGG: slo:Shew_2004 hypothetical protein YP_001501959.1 KEGG: slo:Shew_2002 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001501960.1 KEGG: slo:Shew_2001 hypothetical protein YP_001501961.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent YP_001501962.1 PFAM: DsrC family protein; KEGG: shm:Shewmr7_2007 DsrC family protein YP_001501963.1 PFAM: DsrH family protein; KEGG: shn:Shewana3_2057 DsrH family protein YP_001501964.1 PFAM: DsrE family protein; KEGG: sbm:Shew185_2207 DsrE family protein YP_001501965.1 PFAM: DsrE family protein; KEGG: slo:Shew_2015 DsrE family protein YP_001501966.1 PFAM: protein of unknown function UPF0005; KEGG: sbm:Shew185_2205 protein of unknown function UPF0005 YP_001501967.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_2013 transcriptional regulator, LysR family YP_001501968.1 uncharacterized member of the major facilitator superfamily (MFS) YP_001501969.1 KEGG: pha:PSHAa2145 3 alpha-hydroxysteroid dehydrogenase/carbonyl reductase YP_001501970.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: pha:PSHAa2144 transporter YP_001501971.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate YP_001501972.1 catalyzes the formation of acetyl-CoA from acetalaldehyde YP_001501973.1 PFAM: Hydratase/decarboxylase; KEGG: pha:PSHAa2141 2-hydroxypent-2,4-dienoate hydratase (HPH) (2-oxopent-4-enoate hydratase) YP_001501974.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: pha:PSHAa2140 TesA protein YP_001501975.1 PFAM: aldehyde dehydrogenase; KEGG: pha:PSHAa2139 aldehyde dehydrogenase YP_001501976.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: pha:PSHAa2137 protein with ferredoxin subunits YP_001501977.1 PFAM: major facilitator superfamily MFS_1; KEGG: pha:PSHAa2136 transporter YP_001501978.1 PFAM: beta-lactamase domain protein; KEGG: pha:PSHAa2135 metallo-dependent enzymatic protein YP_001501979.1 PFAM: AMP-dependent synthetase and ligase; KEGG: pha:PSHAa2134 AMP-binding enzyme YP_001501980.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: pha:PSHAa2133 3-ketosteroid-delta1-dehydrogenase YP_001501981.1 activates fatty acids by binding to coenzyme A YP_001501982.1 KEGG: reu:Reut_A1574 hypothetical protein YP_001501983.1 KEGG: reu:Reut_A1573 glycosyl hydrolase, BNR repeat YP_001501984.1 PFAM: Acyl-CoA dehydrogenase type 2 domain; KEGG: pha:PSHAa0877 steroid degradation protein YP_001501985.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: pha:PSHAa0878 reductase protein YP_001501986.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pha:PSHAa0879 3-oxoacyl-(ACP) reductase YP_001501987.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: pha:PSHAa0880 NADPH dehydrogenase YP_001501988.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: dar:Daro_1211 electron transfer flavoprotein beta-subunit YP_001501989.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit ; Electron transfer flavoprotein alpha subunit; KEGG: eba:ebA6510 electron transfer flavoprotein alpha subunit YP_001501990.1 PFAM: regulatory protein LuxR; KEGG: pha:PSHAa0881 LuxR-type transcription regulator required for testosterone degradation YP_001501991.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001501992.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pha:PSHAa0883 short chain dehydrogenase YP_001501993.1 PFAM: protein of unknown function DUF35; KEGG: pha:PSHAa0884 hypothetical protein YP_001501994.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: pha:PSHAa0885 acyl-CoA dehydrogenase protein YP_001501995.1 PFAM: MaoC domain protein dehydratase; KEGG: pha:PSHAa0886 hypothetical protein YP_001501996.1 KEGG: pha:PSHAa0887 lipid-transfer protein YP_001501997.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pha:PSHAa0888 acyl-CoA dehydrogenase protein YP_001501998.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pha:PSHAa0889 acyl-CoA dehydrogenase protein YP_001501999.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pha:PSHAa0890 acyl-CoA dehydrogenase protein YP_001502000.1 PFAM: protein of unknown function DUF523; KEGG: mmw:Mmwyl1_2745 protein of unknown function DUF523 YP_001502001.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pha:PSHAa0892 electron acceptor reductase/NADH oxidase, FAD binding, iron-sulfur cluster binding site YP_001502002.1 PFAM: alpha/beta hydrolase fold; KEGG: pha:PSHAa0893 hydrolase acting on oxygenated substrates (epoxide hydrolase) YP_001502003.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pha:PSHAa0894 3-ketoacyl-(ACP) reductase YP_001502004.1 KEGG: pha:PSHAa0895 enzyme YP_001502005.1 activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization YP_001502006.1 KEGG: pha:PSHAa0897 nonspecific lipid-transfer protein YP_001502007.1 PFAM: MaoC domain protein dehydratase; protein of unknown function DUF35; KEGG: pha:PSHAa0898 acyl dehydratase YP_001502008.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: pha:PSHAa0900 dioxygenase YP_001502009.1 PFAM: coenzyme A transferase; KEGG: pha:PSHAa0901 acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit YP_001502010.1 PFAM: coenzyme A transferase; KEGG: pha:PSHAa0902 acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit YP_001502011.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001502012.1 PFAM: 2-nitropropane dioxygenase NPD; KEGG: pha:PSHAa0904 dioxygenase YP_001502013.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001502014.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pha:PSHAa0906 isovaleryl-CoA dehydrogenase YP_001502015.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: pha:PSHAa0907 butyryl-CoA dehydrogenase YP_001502016.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001502017.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pha:PSHAa0909 short chain dehydrogenase YP_001502018.1 PFAM: Amidase; KEGG: pha:PSHAa0910 allophanate hydrolase YP_001502019.1 KEGG: son:SO_4704 hypothetical protein YP_001502021.1 PFAM: protein of unknown function DUF1302; KEGG: bur:Bcep18194_B1461 protein of unknown function DUF1302 YP_001502022.1 PFAM: protein of unknown function DUF1329; KEGG: reu:Reut_A1519 protein of unknown function DUF1329 YP_001502023.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pha:PSHAa2151 short chain dehydrogenase YP_001502024.1 PFAM: MaoC domain protein dehydratase; KEGG: pha:PSHAa2150 MaoC-like deshydratase domain YP_001502025.1 KEGG: reu:Reut_A1572 thiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001502026.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: pat:Patl_3812 enoyl-CoA hydratase/isomerase YP_001502027.1 PFAM: FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase; KEGG: pen:PSEEN3660 electron transfer flavoprotein-ubiquinone oxidoreductase YP_001502028.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: gme:Gmet_2217 short-chain dehydrogenase/reductase SDR YP_001502029.1 PFAM: nuclear transport factor 2; KEGG: nca:Noca_3954 nuclear transport factor 2 YP_001502030.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: pha:PSHAa2131 acyl-CoA dehydrogenase protein YP_001502031.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pha:PSHAa2130 acyl-CoA dehydrogenase protein YP_001502032.1 PFAM: acriflavin resistance protein; KEGG: sfr:Sfri_1929 acriflavin resistance protein YP_001502033.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sfr:Sfri_1930 efflux transporter, RND family, MFP subunit YP_001502034.1 PFAM: SEC-C motif domain protein; KEGG: shw:Sputw3181_1017 sec-C motif domain protein YP_001502035.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001502036.1 KEGG: ppr:PBPRB0364 putative ATP-dependent protease La-relatedprotein YP_001502037.1 PFAM: peptidase U32; KEGG: ppr:PBPRA1758 putative collagenase family protease YP_001502038.1 KEGG: ppr:PBPRB1179 hypothetical protein YP_001502039.1 KEGG: sfr:Sfri_3117 hypothetical protein YP_001502040.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_001502041.1 PFAM: beta-lactamase domain protein; KEGG: son:SO_A0149 hypothetical protein YP_001502042.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001502043.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: vvu:VV2_0788 purine-cytosine permease YP_001502044.1 KEGG: gur:Gura_3576 hypothetical protein YP_001502045.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: vvy:VVA0679 permease YP_001502046.1 PFAM: secretion protein HlyD family protein; KEGG: vvy:VVA0680 multidrug resistance efflux pump YP_001502047.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_2037 efflux transporter, RND family, MFP subunit YP_001502048.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_2036 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family YP_001502049.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: shm:Shewmr7_2035 RND efflux system, outer membrane lipoprotein, NodT family YP_001502050.1 PFAM: UMUC domain protein DNA-repair protein; KEGG: sdn:Sden_3235 DNA-directed DNA polymerase YP_001502051.1 PFAM: peptidase S24 and S26 domain protein; KEGG: sfr:Sfri_1963 putative prophage repressor YP_001502052.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: vfi:VFA0342 sensory transduction protein kinase YP_001502053.1 PFAM: AraC protein arabinose-binding/dimerisation; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: ppr:PBPRB0725 hypothetical protein YP_001502054.1 KEGG: ppr:PBPRB0729 hypothetical protein YP_001502055.1 PFAM: Appr-1-p processing domain protein; KEGG: ehi:379.t00002 conserved hypothetical protein Pfam: Macro SIR2 PROSITE: SIRTUIN YP_001502056.1 KEGG: ehi:379.t00002 conserved hypothetical protein Pfam: Macro SIR2 PROSITE: SIRTUIN YP_001502058.1 KEGG: cvi:CV_1450 hypothetical protein YP_001502059.1 KEGG: dme:Dmel_CG4335 CG4335; TIGRFAM: trimethyllysine dioxygenase; PFAM: Taurine catabolism dioxygenase TauD/TfdA YP_001502060.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: gme:Gmet_0270 aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001502061.1 PFAM: amino acid permease-associated region; Amino acid transporter transmembrane; KEGG: cvi:CV_3432 probable amino acid permease YP_001502062.1 KEGG: vha:VIBHAR_03071 hypothetical protein YP_001502063.1 PFAM: GCN5-related N-acetyltransferase; KEGG: vpa:VP1794 hypothetical protein YP_001502064.1 KEGG: cps:CPS_3017 hypothetical protein YP_001502066.1 PFAM: integrase family protein; KEGG: sbm:Shew185_2174 phage integrase family protein YP_001502067.1 KEGG: spc:Sputcn32_1997 hypothetical protein YP_001502068.1 KEGG: sfr:Sfri_2009 hypothetical protein YP_001502069.1 CcoN; FixN YP_001502070.1 CcoO; FixO YP_001502071.1 PFAM: Cbb3-type cytochrome oxidase component; KEGG: sdn:Sden_1849 Cbb3-type cytochrome oxidase component YP_001502072.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III; PFAM: cytochrome c class I; KEGG: sbl:Sbal_4490 hypothetical protein YP_001502073.1 KEGG: slo:Shew_1989 hypothetical protein YP_001502074.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: shn:Shewana3_2112 heavy metal translocating P-type ATPase YP_001502075.1 TIGRFAM: cytochrome oxidase maturation protein, cbb3-type; PFAM: cytochrome oxidase maturation protein cbb3-type; KEGG: sfr:Sfri_2016 cytochrome oxidase maturation protein, cbb3-type YP_001502076.1 KEGG: sbl:Sbal_4494 hypothetical protein YP_001502077.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_001502078.1 with UspC and UspD is involved in resistance to UV irradiation YP_001502079.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001502080.1 KEGG: slo:Shew_1996 hypothetical protein YP_001502081.1 KEGG: slo:Shew_1997 Bax protein, putative YP_001502082.1 PFAM: protein of unknown function UPF0052 and CofD; KEGG: slo:Shew_1998 protein of unknown function UPF0052 and CofD YP_001502083.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001502084.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001502085.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001502086.1 PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: slo:Shew_2022 AAA ATPase, central domain protein YP_001502087.1 PFAM: outer membrane lipoprotein carrier protein LolA; KEGG: shn:Shewana3_2051 outer membrane lipoprotein carrier protein LolA YP_001502088.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: slo:Shew_2024 cell divisionFtsK/SpoIIIE YP_001502089.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_001502090.1 TIGRFAM: alanine dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Shikimate/quinate 5-dehydrogenase; alanine dehydrogenase/PNT domain protein; KEGG: slo:Shew_2026 alanine dehydrogenase YP_001502091.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO_2426 DNA-binding response regulator YP_001502092.1 PFAM: protein of unknown function DUF885; KEGG: sbm:Shew185_2005 protein of unknown function DUF885 YP_001502093.1 KEGG: pin:Ping_3396 23S rRNA (Gm2251)-methyltransferase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases YP_001502094.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: slo:Shew_1933 endonuclease/exonuclease/phosphatase YP_001502095.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_001502096.1 KEGG: she:Shewmr4_3608 hypothetical protein YP_001502097.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; Nitrate and nitrite sensing domain protein; KEGG: sbm:Shew185_1950 methyl-accepting chemotaxis sensory transducer YP_001502098.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001502099.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: sbm:Shew185_2151 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase YP_001502100.1 PFAM: Transketolase central region; Transketolase domain protein; KEGG: sbl:Sbal_4507 hypothetical protein YP_001502101.1 PFAM: dehydrogenase E1 component; KEGG: slo:Shew_1925 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) YP_001502102.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_001502103.1 TIGRFAM: peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A; KEGG: sfr:Sfri_1933 peptide methionine sulfoxide reductase YP_001502104.1 KEGG: sfr:Sfri_2052 hypothetical protein YP_001502106.1 PFAM: conserved hypothetical protein; KEGG: vfi:VF1977 protein YgiW precursor YP_001502107.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sfr:Sfri_2144 NADH:flavin oxidoreductase/NADH oxidase YP_001502108.1 KEGG: slo:Shew_1941 signal peptide peptidase SppA, 67K type; TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: peptidase S49 YP_001502109.1 converts asparagine to aspartate and ammonia YP_001502110.1 PFAM: protein of unknown function DUF1315; KEGG: slo:Shew_1939 protein of unknown function DUF1315 YP_001502111.1 KEGG: slo:Shew_1938 hypothetical protein YP_001502112.1 PFAM: peptidase M14 carboxypeptidase A; KEGG: slo:Shew_1937 peptidase M14, carboxypeptidase A YP_001502113.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: slo:Shew_2028 thioredoxin reductase YP_001502114.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdn:Sden_1712 GCN5-related N-acetyltransferase YP_001502115.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001502116.1 PFAM: ribosomal protein L35; KEGG: slo:Shew_2030 ribosomal protein L35 YP_001502117.1 TIGRFAM: translation initiation factor IF-3; PFAM: initiation factor 3; KEGG: slo:Shew_2031 translation initiation factor IF-3 YP_001502118.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001502120.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: saz:Sama_1764 short-chain dehydrogenase/reductase SDR YP_001502121.1 KEGG: shn:Shewana3_2041 hypothetical protein YP_001502122.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001502123.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: slo:Shew_2037 MATE efflux family protein YP_001502124.1 KEGG: sfr:Sfri_3563 transposase YP_001502125.1 PFAM: PEBP family protein; KEGG: aeh:Mlg_1616 YbhB and YbcL YP_001502126.1 PFAM: major facilitator superfamily MFS_1; KEGG: yen:YE3963 conserved integral membrane protein YP_001502127.1 PFAM: pentapeptide repeat protein; KEGG: vpa:VPA1301 hypothetical protein YP_001502129.1 PFAM: GCN5-related N-acetyltransferase; KEGG: vha:VIBHAR_05434 hypothetical protein YP_001502130.1 KEGG: sdn:Sden_1029 hypothetical protein YP_001502131.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sdn:Sden_1155 radical SAM YP_001502132.1 PFAM: peptidase S15; KEGG: sde:Sde_2300 dipeptidyl aminopeptidases/acylaminoacyl-peptidases-like YP_001502134.1 PFAM: major facilitator superfamily MFS_1; KEGG: vfi:VFA0067 oxalate/formate antiporter YP_001502135.1 KEGG: sfr:Sfri_0770 hypothetical protein YP_001502136.1 KEGG: bld:BLi00510 YdaE YP_001502137.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: rru:Rru_A0247 periplasmic binding protein/LacI transcriptional regulator YP_001502138.1 PFAM: inner-membrane translocator; KEGG: ypi:YpsIP31758_0911 ribose ABC transporter, permease protein YP_001502139.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sgl:SG0612 sugar ABC transporter ATP-binding component YP_001502140.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: mmw:Mmwyl1_1989 xylulokinase YP_001502141.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: plu:plu1960 hypothetical protein YP_001502142.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: hch:HCH_02466 transcriptional regulator YP_001502143.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ppr:PBPRA1657 putative Uup, ATPase components of ABC transporters with duplicated ATPase domains YP_001502144.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: vha:VIBHAR_07054 hypothetical protein YP_001502145.1 PFAM: phospholipase A1; KEGG: vha:VIBHAR_02841 hypothetical protein YP_001502146.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001502147.1 PFAM: UvrD/REP helicase; DNA topoisomerase type IA zn finger domain protein; KEGG: sfr:Sfri_0452 UvrD/REP helicase YP_001502149.1 PFAM: protein of unknown function UPF0118; KEGG: vfi:VF2136 hypothetical membrane spanning protein YP_001502150.1 PFAM: glutathione synthase; glutathione synthase ATP-binding; KEGG: shn:Shewana3_2339 glutathione synthase, ATP-binding YP_001502151.1 KEGG: saz:Sama_1875 hypothetical protein YP_001502152.1 KEGG: saz:Sama_1874 hypothetical protein YP_001502153.1 PFAM: ATP-binding region ATPase domain protein; Two component regulator propeller; histidine kinase dimerisation and phosphoacceptor region; KEGG: saz:Sama_1872 sensor histidine kinase YP_001502154.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: saz:Sama_1873 response regulator receiver protein YP_001502155.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; protease-associated PA domain protein; KEGG: saz:Sama_1876 peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001502156.1 KEGG: ppr:PBPRB0896 hypothetical protein YP_001502157.1 KEGG: sfr:Sfri_2082 hypothetical protein YP_001502158.1 KEGG: sfr:Sfri_2083 hypothetical protein YP_001502159.1 KEGG: rrs:RoseRS_0345 hypothetical protein YP_001502160.1 KEGG: ent:Ent638_0472 hypothetical protein YP_001502161.1 PFAM: phosphoadenosine phosphosulfate reductase; KEGG: ent:Ent638_0471 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PapS reductase)/FAD synthetase and related enzyme YP_001502162.1 PFAM: SMC domain protein; KEGG: ent:Ent638_0470 SMC domain protein YP_001502163.1 PFAM: Domain of unknown function DUF1832; KEGG: ent:Ent638_0469 hypothetical protein YP_001502164.1 PFAM: sigma-70 region 4 domain protein; KEGG: fal:FRAAL2026 RNA polymerase essential primary sigma 70 factor YP_001502166.1 KEGG: mbu:Mbur_1538 ATPase involved in DNA repair-like protein YP_001502167.1 KEGG: hwa:HQ2075A predicted ATPase invovled in DNA repair YP_001502168.1 PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: gur:Gura_2481 type III restriction enzyme, res subunit YP_001502169.1 SMART: HNH nuclease; KEGG: plu:plu4325 hypothetical protein YP_001502170.1 KEGG: ent:Ent638_0466 hypothetical protein YP_001502171.1 KEGG: pha:PSHAb0090 putative orphan protein YP_001502172.1 KEGG: pha:PSHAb0089 hypothetical protein YP_001502173.1 PFAM: protein of unknown function UPF0153; KEGG: cps:CPS_2552 hypothetical protein YP_001502174.1 TIGRFAM: putative AcnD-accessory protein PrpF; PFAM: protein of unknown function DUF453; KEGG: sfr:Sfri_1860 putative AcnD-accessory protein PrpF YP_001502175.1 Catalyzes the conversion of citrate to isocitrate YP_001502176.1 KEGG: slo:Shew_1821 2-methylcitrate synthase/citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase YP_001502177.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_001502178.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: pat:Patl_1418 transcriptional regulator, GntR family YP_001502179.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: shm:Shewmr7_1876 CoA-binding domain protein YP_001502180.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: slo:Shew_2040 diguanylate cyclase YP_001502181.1 PFAM: sulfatase; protein of unknown function DUF1705; KEGG: slo:Shew_2041 protein of unknown function DUF1705 YP_001502182.1 PFAM: regulatory protein MarR; KEGG: sbm:Shew185_2256 transcriptional regulator, MarR family YP_001502183.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: slo:Shew_2043 cation diffusion facilitator family transporter YP_001502184.1 serine protease inhibitor, inhibits trypsin and other proteases YP_001502185.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3562 integrase, catalytic region YP_001502186.1 KEGG: sfr:Sfri_3563 transposase YP_001502187.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001502188.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001502189.1 TIGRFAM: 6-phosphogluconolactonase; KEGG: slo:Shew_2047 6-phosphogluconolactonase YP_001502190.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001502191.1 Represses the expression of the zwf, eda, glp and gap YP_001502192.1 KEGG: slo:Shew_2050 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta YP_001502193.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001502194.1 PFAM: regulatory protein TetR; KEGG: slo:Shew_2052 transcriptional regulator, TetR family YP_001502195.1 PFAM: peptidase M2 peptidyl-dipeptidase A; KEGG: slo:Shew_2053 peptidyl-dipeptidase A YP_001502196.1 PFAM: Smr protein/MutS2; KEGG: she:Shewmr4_2052 Smr protein/MutS2 YP_001502197.1 KEGG: slo:Shew_2055 hypothetical protein YP_001502198.1 PFAM: SEC-C motif domain protein; KEGG: sfr:Sfri_1884 sec-C motif domain protein YP_001502199.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: slo:Shew_2057 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) YP_001502200.1 KEGG: slo:Shew_2058 hypothetical protein YP_001502201.1 KEGG: shn:Shewana3_2162 hypothetical protein YP_001502202.1 PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sbm:Shew185_2117 pyridoxal-5'-phosphate-dependent protein beta subunit YP_001502203.1 PFAM: Radical SAM domain protein; KEGG: son:SO_2501 radical activating enzyme YP_001502204.1 TIGRFAM: exsB protein; PFAM: ExsB family protein; KEGG: sbl:Sbal_4541 hypothetical protein YP_001502205.1 PFAM: Rhomboid family protein; KEGG: she:Shewmr4_2060 rhomboid family protein YP_001502206.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001502207.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: sbl:Sbal_4544 hypothetical protein YP_001502208.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: shm:Shewmr7_1911 electron transport complex, RnfABCDGE type, A subunit YP_001502209.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001502210.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001502211.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_001502212.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_001502213.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_001502214.1 KEGG: she:Shewmr4_2070 endonuclease III; TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_001502215.1 KEGG: shm:Shewmr7_1867 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001502216.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: slo:Shew_2074 TonB-dependent receptor YP_001502217.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001502218.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001502219.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001502220.1 PFAM: protein of unknown function DUF28; KEGG: slo:Shew_2078 protein of unknown function DUF28 YP_001502221.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001502222.1 KEGG: shw:Sputw3181_2074 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; myoactive tetradecapeptide family protein; SMART: extracellular solute-binding protein family 3 YP_001502223.1 TIGRFAM: putative methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: slo:Shew_2081 putative methyltransferase YP_001502224.1 TIGRFAM: putative methyltransferase; PFAM: methyltransferase putative; Methyltransferase type 11; Methyltransferase type 12; KEGG: sbm:Shew185_2310 putative methyltransferase YP_001502225.1 PFAM: protein of unknown function DUF785; KEGG: slo:Shew_2083 protein of unknown function DUF785 YP_001502226.1 KEGG: slo:Shew_2084 gonadoliberin III-related protein YP_001502227.1 TIGRFAM: alpha-L-glutamate ligase-like protein; KEGG: slo:Shew_2085 alpha-L-glutamate ligase-like protein YP_001502228.1 KEGG: spc:Sputcn32_1931 peptidase M3A and M3B, thimet/oligopeptidase F YP_001502229.1 KEGG: slo:Shew_2087 hypothetical protein YP_001502230.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: vfi:VFA0360 sensory transduction protein kinase YP_001502231.1 KEGG: saz:Sama_1854 conserved hypothetical methyl-accepting chemotaxis protein YP_001502232.1 PFAM: response regulator receiver; KEGG: slo:Shew_0703 response regulator receiver protein YP_001502233.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_001502234.1 PFAM: thiazole biosynthesis family protein; KEGG: sfr:Sfri_2197 thiazole biosynthesis family protein YP_001502235.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: shw:Sputw3181_2083 thiamine biosynthesis protein ThiS YP_001502236.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: shn:Shewana3_1938 UBA/ThiF-type NAD/FAD binding protein YP_001502237.1 KEGG: son:SO_2444 phosphomethylpyrimidine kinase / thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; phosphomethylpyrimidine kinase; PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1 YP_001502238.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001502239.1 KEGG: shn:Shewana3_1935 hypothetical protein YP_001502240.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: sbm:Shew185_2325 channel protein, hemolysin III family YP_001502241.1 PFAM: DTW domain containing protein; KEGG: slo:Shew_2099 DTW domain containing protein YP_001502242.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001502243.1 PFAM: major facilitator superfamily MFS_1; KEGG: slo:Shew_2104 major facilitator superfamily MFS_1 YP_001502245.1 PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: shn:Shewana3_2320 methylated-DNA-(protein)-cysteine S-methyltransferase YP_001502246.1 KEGG: she:Shewmr4_2144 hypothetical protein YP_001502247.1 PFAM: glutamine amidotransferase class-II; KEGG: slo:Shew_2107 glutamine amidotransferase, class-II YP_001502248.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001502249.1 KEGG: sfr:Sfri_0076 radical SAM domain protein; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001502252.1 KEGG: ppr:PBPRB0447 putative serine transporter YP_001502253.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; CHASE3 domain protein; KEGG: ppr:PBPRA0989 hypothetical methyl-accepting chemotaxis protein YP_001502254.1 KEGG: she:Shewmr4_1472 hypothetical protein YP_001502255.1 PFAM: sodium/hydrogen exchanger; KEGG: sbm:Shew185_2017 sodium/hydrogen exchanger YP_001502256.1 KEGG: slo:Shew_2110 hypothetical protein YP_001502257.1 KEGG: slo:Shew_2111 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease YP_001502258.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001502259.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbm:Shew185_2013 transcriptional regulator, LysR family YP_001502260.1 PFAM: Methyltransferase type 11; KEGG: slo:Shew_2113 hypothetical protein YP_001502261.1 PFAM: beta-lactamase domain protein; KEGG: slo:Shew_2114 hydroxyacylglutathione hydrolase YP_001502262.1 PFAM: Peptidoglycan-binding LysM; Lytic transglycosylase catalytic; MLTD_N domain protein; KEGG: slo:Shew_2115 lytic transglycosylase, catalytic YP_001502263.1 KEGG: shw:Sputw3181_2251 intracellular proteinase inhibitor domain protein YP_001502264.1 PFAM: AsmA family protein; KEGG: slo:Shew_2116 AsmA family protein YP_001502265.1 TIGRFAM: regulator of ribonuclease activity A; PFAM: Dimethylmenaquinone methyltransferase; KEGG: sbm:Shew185_2007 regulator of ribonuclease activity A YP_001502266.1 KEGG: sbm:Shew185_2006 hypothetical protein YP_001502267.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001502268.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001502269.1 PFAM: protein of unknown function DUF195; KEGG: slo:Shew_2124 protein of unknown function DUF195 YP_001502270.1 PFAM: Lytic transglycosylase catalytic; KEGG: slo:Shew_2125 lytic transglycosylase, catalytic YP_001502271.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: slo:Shew_2126 ATPase associated with various cellular activities, AAA_3 YP_001502272.1 PFAM: protein of unknown function DUF58; KEGG: sbl:Sbal_4562 hypothetical protein YP_001502273.1 PFAM: transglutaminase domain protein; KEGG: shw:Sputw3181_1903 transglutaminase domain protein YP_001502274.1 TIGRFAM: exodeoxyribonuclease V, gamma subunit; PFAM: Exodeoxyribonuclease V RecC subunit; KEGG: slo:Shew_2129 exodeoxyribonuclease V, gamma subunit YP_001502275.1 TIGRFAM: exodeoxyribonuclease V, beta subunit; PFAM: UvrD/REP helicase; KEGG: slo:Shew_2130 exodeoxyribonuclease V, beta subunit YP_001502276.1 TIGRFAM: exodeoxyribonuclease V, alpha subunit; KEGG: slo:Shew_2131 exodeoxyribonuclease V, alpha subunit YP_001502277.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001502278.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3340 integrase, catalytic region YP_001502279.1 KEGG: mmw:Mmwyl1_3491 transposase YP_001502280.1 TIGRFAM: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family; PFAM: NapC/NirT cytochrome c domain protein; KEGG: saz:Sama_1624 periplasmic nitrate reductase C-type cytochrome, NapC/NirT YP_001502281.1 PFAM: Nitrate reductase cytochrome c-type subunit (NapB); KEGG: shn:Shewana3_1901 nitrate reductase cytochrome c-type subunit (NapB) YP_001502282.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001502283.1 PFAM: NapD family protein; KEGG: sbl:Sbal_1909 NapD family protein YP_001502284.1 PFAM: periplasmic nitrate reductase NapE; KEGG: slo:Shew_1768 periplasmic nitrate reductase NapE YP_001502285.1 KEGG: slo:Shew_1767 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD-like helicases YP_001502286.1 PFAM: CBS domain containing protein; KEGG: shm:Shewmr7_2139 putative signal transduction protein with CBS domains YP_001502288.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_001502289.1 KEGG: vpa:VPA0120 hypothetical protein YP_001502290.1 PFAM: peptidase T2 asparaginase 2; KEGG: slo:Shew_2171 peptidase T2, asparaginase 2 YP_001502291.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: she:Shewmr4_1836 surface antigen (D15) YP_001502292.1 PFAM: protein of unknown function DUF490; KEGG: slo:Shew_2173 protein of unknown function DUF490 YP_001502293.1 Multifunctional regulator of fatty acid metabolism YP_001502294.1 involved in regulation of intracellular pH under alkaline conditions YP_001502295.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_001502296.1 PFAM: protein of unknown function UPF0153; KEGG: sbm:Shew185_1898 protein of unknown function UPF0153 YP_001502297.1 TIGRFAM: lytic murein transglycosylase; KEGG: sbl:Sbal_1870 lytic murein transglycosylase YP_001502298.1 PFAM: protein of unknown function DUF709; KEGG: slo:Shew_2183 protein of unknown function DUF709 YP_001502299.1 blocks the formation of polar Z-ring septums YP_001502300.1 TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid ac-diamide synthase; KEGG: slo:Shew_2185 septum site-determining protein MinD YP_001502301.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001502302.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: sdn:Sden_1626 ribonuclease D YP_001502303.1 Activates fatty acids by binding to coenzyme A YP_001502304.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: shm:Shewmr7_2255 alpha/beta hydrolase fold YP_001502305.1 KEGG: slo:Shew_2190 hypothetical protein YP_001502306.1 KEGG: shw:Sputw3181_2267 hypothetical protein YP_001502307.1 KEGG: shw:Sputw3181_2268 hypothetical protein YP_001502308.1 PFAM: peptidase M22 glycoprotease; KEGG: sbm:Shew185_1886 peptidase M22 glycoprotease YP_001502310.1 SMART: helicase c2; DEAD-like helicases; KEGG: slo:Shew_2196 helicase C2 YP_001502311.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_001502312.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001502313.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001502314.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_001502315.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001502316.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001502317.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001502318.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_001502319.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001502320.1 KEGG: mmw:Mmwyl1_3491 transposase YP_001502321.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3340 integrase, catalytic region YP_001502322.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_001502323.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001502324.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001502325.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001502326.1 PFAM: chemotaxis sensory transducer; KEGG: slo:Shew_2217 methyl-accepting chemotaxis sensory transducer YP_001502327.1 KEGG: sbm:Shew185_1768 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein YP_001502328.1 PFAM: protein of unknown function DUF785; KEGG: slo:Shew_2219 protein of unknown function DUF785 YP_001502329.1 KEGG: slo:Shew_2221 hypothetical protein YP_001502330.1 KEGG: slo:Shew_2222 hypothetical protein YP_001502331.1 PFAM: YceI family protein; KEGG: son:SO_2893 hypothetical protein YP_001502332.1 KEGG: slo:Shew_1622 pyridoxamine 5'-phosphate oxidase; TIGRFAM: pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding YP_001502333.1 catalyzes the formation of putrescine from agmatine YP_001502334.1 PFAM: S-adenosylmethionine decarboxylase; KEGG: saz:Sama_1962 adenosylmethionine decarboxylase YP_001502335.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001502336.1 KEGG: slo:Shew_1618 hypothetical protein YP_001502337.1 PFAM: protein of unknown function DUF480; KEGG: she:Shewmr4_1554 protein of unknown function DUF480 YP_001502338.1 KEGG: shn:Shewana3_1621 hypothetical protein YP_001502339.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shw:Sputw3181_2383 ABC transporter related YP_001502340.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: slo:Shew_1614 cold-shock DNA-binding domain protein YP_001502341.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_001502342.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_001502343.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001502344.1 PFAM: oxidoreductase domain protein; NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: slo:Shew_1609 6-phosphogluconate dehydrogenase, NAD-binding YP_001502345.1 PFAM: thioesterase superfamily protein; KEGG: slo:Shew_1607 thioesterase superfamily protein YP_001502346.1 KEGG: shm:Shewmr7_2463 hypothetical protein YP_001502347.1 PFAM: Beta-ketoacyl synthase; KEGG: shm:Shewmr7_2464 beta-ketoacyl synthase YP_001502348.1 carries the fatty acid chain in fatty acid biosynthesis YP_001502349.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: son:SO_2776 3-oxoacyl-[acyl-carrier protein] reductase YP_001502350.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: sbm:Shew185_1715 malonyl CoA-acyl carrier protein transacylase YP_001502351.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001502352.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001502353.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001502354.1 PFAM: protein of unknown function DUF177; KEGG: son:SO_2781 hypothetical protein YP_001502355.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: son:SO_2782 maf protein, putative YP_001502356.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: slo:Shew_1596 diguanylate cyclase with PAS/PAC sensor YP_001502357.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: slo:Shew_1595 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_001502358.1 KEGG: slo:Shew_1594 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001502359.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: slo:Shew_1593 ribonuclease, Rne/Rng family YP_001502360.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: slo:Shew_1592 sulphate transporter YP_001502361.1 this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae YP_001502362.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: slo:Shew_1590 2OG-Fe(II) oxygenase YP_001502363.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_001502364.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: saz:Sama_1994 protein tyrosine phosphatase YP_001502365.1 PFAM: nitroreductase; KEGG: sdn:Sden_2794 nitroreductase YP_001502366.1 catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_001502367.1 PFAM: diacylglycerol kinase; KEGG: shn:Shewana3_2402 diacylglycerol kinase YP_001502368.1 KEGG: slo:Shew_1585 hypothetical protein YP_001502369.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sbm:Shew185_1831 diguanylate cyclase YP_001502370.1 TIGRFAM: sortase family protein; PFAM: peptidase C60 sortase A and B; KEGG: she:Shewmr4_2199 sortase family protein YP_001502371.1 KEGG: shm:Shewmr7_2277 vault protein inter-alpha-trypsin domain protein; TIGRFAM: LPXTG-motif cell wall anchor domain; PFAM: von Willebrand factor type A; Vault protein inter-alpha-trypsin domain protein; SMART: Vault protein inter-alpha-trypsin, metazoa YP_001502372.1 PFAM: OmpA/MotB domain protein; KEGG: sfr:Sfri_1624 OmpA/MotB domain protein YP_001502373.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: slo:Shew_1791 two component transcriptional regulator, winged helix family YP_001502374.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: slo:Shew_1790 integral membrane sensor signal transduction histidine kinase YP_001502375.1 catalyzes the formation of L-homocysteine from cystathionine YP_001502376.1 KEGG: vfi:VF1617 hypothetical protein YP_001502377.1 PFAM: CreA family protein; KEGG: shn:Shewana3_2415 CreA family protein YP_001502378.1 KEGG: slo:Shew_1787 hypothetical protein YP_001502379.1 PFAM: Rhodanese domain protein; KEGG: sdn:Sden_2100 rhodanese-like protein YP_001502380.1 PFAM: Glutathione S-transferase domain; KEGG: slo:Shew_1780 glutathione S-transferase, N-terminal domain YP_001502381.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shn:Shewana3_2265 lysine exporter protein (LysE/YggA) YP_001502382.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: sbl:Sbal_2383 putative transcriptional regulator, GntR family YP_001502383.1 PFAM: 17 kDa surface antigen; KEGG: slo:Shew_1570 17 kDa surface antigen YP_001502384.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001502385.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_001502386.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001502387.1 KEGG: slo:Shew_1566 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001502388.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001502389.1 KEGG: sbm:Shew185_2467 putative cold-shock DNA-binding domain protein; TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein YP_001502390.1 KEGG: sfr:Sfri_2257 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type YP_001502391.1 PFAM: pseudouridine synthase; KEGG: she:Shewmr4_1605 pseudouridine synthase, Rsu YP_001502392.1 PFAM: NUDIX hydrolase; KEGG: sfr:Sfri_2259 NUDIX hydrolase YP_001502393.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001502394.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_001502395.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001502396.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji jmjC domain protein; KEGG: spc:Sputcn32_2236 cupin 4 family protein YP_001502397.1 KEGG: sfr:Sfri_2264 hypothetical protein YP_001502398.1 PFAM: Glu/Leu/Phe/Val dehydrogenase ; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: slo:Shew_1555 Glu/Leu/Phe/Val dehydrogenase, dimerisation region YP_001502399.1 KEGG: shw:Sputw3181_1770 hypothetical protein YP_001502400.1 KEGG: slo:Shew_1553 hypothetical protein YP_001502401.1 PFAM: regulatory protein MarR; KEGG: shm:Shewmr7_1670 transcriptional regulator, MarR family YP_001502402.1 KEGG: son:SO_2642 hypothetical protein YP_001502403.1 PFAM: FAD linked oxidase domain protein; KEGG: shw:Sputw3181_1766 FAD linked oxidase domain protein YP_001502404.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001502405.1 PFAM: protein of unknown function DUF299; KEGG: slo:Shew_1548 protein of unknown function DUF299 YP_001502406.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_001502407.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sbm:Shew185_0944 GCN5-related N-acetyltransferase YP_001502408.1 PFAM: thioesterase superfamily protein; KEGG: saz:Sama_2075 thioesterase superfamily YP_001502409.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: slo:Shew_1545 two component transcriptional regulator, LuxR family YP_001502410.1 PFAM: FAD dependent oxidoreductase; KEGG: slo:Shew_1537 FAD dependent oxidoreductase YP_001502411.1 KEGG: sfr:Sfri_1438 hypothetical protein YP_001502412.1 PFAM: Na+/solute symporter; response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: slo:Shew_1534 integral membrane sensor hybrid histidine kinase YP_001502413.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001502414.1 PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: shm:Shewmr7_2435 type III restriction enzyme, res subunit YP_001502415.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_001502416.1 PFAM: porin; KEGG: slo:Shew_1530 porin YP_001502417.1 TIGRFAM: Tol-Pal system YbgF; PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: shw:Sputw3181_2413 tetratricopeptide domain protein YP_001502418.1 TIGRFAM: Peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: slo:Shew_1528 OmpA domain protein YP_001502419.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001502420.1 TIGRFAM: Tol-Pal system TolA; PFAM: TolA family protein; KEGG: slo:Shew_1526 TolA family protein YP_001502421.1 TIGRFAM: Biopolymer transport TolR; PFAM: Biopolymer transport protein ExbD/TolR; KEGG: slo:Shew_1525 biopolymer transport protein ExbD/TolR YP_001502422.1 TIGRFAM: Tol-Pal system TolQ; PFAM: MotA/TolQ/ExbB proton channel; KEGG: slo:Shew_1524 MotA/TolQ/ExbB proton channel YP_001502423.1 TIGRFAM: Pol-Pal system-associated acyl-CoA thioesterase; PFAM: thioesterase superfamily protein; KEGG: shn:Shewana3_2535 4-hydroxybenzoyl-CoA thioesterase YP_001502424.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: slo:Shew_1522 prolyl oligopeptidase YP_001502425.1 PFAM: OmpA/MotB domain protein; KEGG: sbm:Shew185_1736 OmpA/MotB domain protein YP_001502426.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_001502427.1 KEGG: sfr:Sfri_3563 transposase YP_001502428.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3562 integrase, catalytic region YP_001502429.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: slo:Shew_1516 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_001502430.1 PFAM: Gluconate transporter; Citrate transporter; Na+/H+ antiporter NhaC; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: slo:Shew_1515 Na+/H+ antiporter NhaC YP_001502431.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001502432.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001502433.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001502434.1 PFAM: protein of unknown function DUF1214; protein of unknown function DUF1254; KEGG: vha:VIBHAR_02425 hypothetical protein YP_001502435.1 KEGG: ppr:PBPRB0205 hypothetical FOG: GGDEF domain; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein YP_001502436.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: saz:Sama_2099 NagD protein YP_001502437.1 PFAM: peptidase M28; KEGG: slo:Shew_1510 peptidase M28 YP_001502438.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_001502439.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: slo:Shew_2412 tRNA/rRNA methyltransferase (SpoU) YP_001502440.1 PFAM: YfcL protein; KEGG: shm:Shewmr7_1484 hypothetical protein YP_001502441.1 PFAM: ATP-NAD/AcoX kinase; KEGG: sbm:Shew185_2767 ATP-NAD/AcoX kinase YP_001502442.1 PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: sbm:Shew185_2768 major facilitator superfamily MFS_1 YP_001502443.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001502444.1 involved in methylation of ribosomal protein L3 YP_001502445.1 PFAM: Smr protein/MutS2; KEGG: slo:Shew_2418 Smr protein/MutS2 YP_001502446.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase; KEGG: slo:Shew_2419 phosphohistidine phosphatase, SixA YP_001502447.1 PFAM: peptidase M16 domain protein; KEGG: slo:Shew_2420 peptidase M16 domain protein YP_001502448.1 KEGG: slo:Shew_2421 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; Two component regulator three Y domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001502449.1 KEGG: saz:Sama_2165 hypothetical protein YP_001502450.1 KEGG: sbm:Shew185_2776 hypothetical protein YP_001502451.1 KEGG: sbm:Shew185_2776 hypothetical protein YP_001502452.1 KEGG: slo:Shew_2424 hypothetical protein YP_001502453.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_001502454.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_001502455.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: sbm:Shew185_2782 ATPase associated with various cellular activities AAA_3 YP_001502456.1 PFAM: protein of unknown function DUF58; KEGG: slo:Shew_2428 protein of unknown function DUF58 YP_001502457.1 KEGG: slo:Shew_2429 hypothetical protein YP_001502458.1 PFAM: von Willebrand factor type A; KEGG: shm:Shewmr7_1468 von Willebrand factor, type A YP_001502459.1 PFAM: TPR repeat-containing protein; von Willebrand factor type A; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: spc:Sputcn32_2465 TPR repeat-containing protein YP_001502460.1 KEGG: sbm:Shew185_2787 hypothetical protein YP_001502461.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001502462.1 KEGG: slo:Shew_2434 hypothetical protein YP_001502463.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: slo:Shew_2435 sodium/proline symporter YP_001502464.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: slo:Shew_2436 membrane protein involved in aromatic hydrocarbon degradation YP_001502465.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sbl:Sbal_2774 efflux transporter, RND family, MFP subunit YP_001502466.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_1458 acriflavin resistance protein YP_001502467.1 KEGG: sbm:Shew185_2796 hypothetical protein YP_001502468.1 PFAM: Rhodanese domain protein; KEGG: shn:Shewana3_1444 rhodanese domain protein YP_001502469.1 KEGG: slo:Shew_2444 hypothetical protein YP_001502470.1 KEGG: sfr:Sfri_2437 hypothetical protein YP_001502471.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_001502472.1 KEGG: sdn:Sden_1446 hypothetical protein YP_001502473.1 TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; KEGG: slo:Shew_2448 anaerobic ribonucleoside-triphosphate reductase activating protein YP_001502474.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_001502475.1 KEGG: sbm:Shew185_1649 hypothetical protein YP_001502476.1 PFAM: regulatory protein MarR; KEGG: slo:Shew_2562 transcriptional regulator, MarR family YP_001502477.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; KEGG: slo:Shew_2563 alcohol dehydrogenase, zinc-binding domain protein YP_001502478.1 PFAM: Patatin; KEGG: son:SO_2836 hypothetical protein YP_001502479.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: slo:Shew_2452 DEAD/DEAH box helicase domain protein YP_001502480.1 KEGG: slo:Shew_2453 hypothetical protein YP_001502481.1 PFAM: protein of unknown function DUF45; KEGG: son:SO_2840 hypothetical protein YP_001502482.1 KEGG: sbm:Shew185_1642 hypothetical protein YP_001502483.1 PFAM: protein of unknown function DUF1568; KEGG: sdn:Sden_3323 protein of unknown function DUF1568 YP_001502484.1 KEGG: sdn:Sden_1131 integron integrase YP_001502485.1 KEGG: bca:BCE_1012 hypothetical protein YP_001502486.1 PFAM: putative transposase; KEGG: sdn:Sden_1136 transposase YP_001502487.1 PFAM: peptidase M23B; Opacity-associated protein A; KEGG: slo:Shew_2455 peptidase M23B YP_001502488.1 PFAM: SMC domain protein; KEGG: sbm:Shew185_1640 SMC domain protein YP_001502489.1 TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase; KEGG: shw:Sputw3181_2568 nuclease SbcCD, D subunit YP_001502490.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_001502491.1 KEGG: ecj:JW5925 predicted inner membrane lipoprotein YP_001502492.1 PFAM: penicillin-binding protein transpeptidase; KEGG: syn:slr0319 beta-lactamase YP_001502493.1 PFAM: protein of unknown function DUF81; KEGG: pin:Ping_1433 permease with 5 transmembrane domains YP_001502494.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: shw:Sputw3181_2570 transcriptional regulator, LysR family YP_001502495.1 PFAM: NERD domain protein; KEGG: slo:Shew_2466 hypothetical protein YP_001502496.1 PFAM: protein of unknown function DUF1260; KEGG: slo:Shew_2467 protein of unknown function DUF1260 YP_001502497.1 KEGG: sbm:Shew185_1635 RNA-binding S4 domain protein YP_001502498.1 PFAM: GCN5-related N-acetyltransferase; KEGG: slo:Shew_2469 GCN5-related N-acetyltransferase YP_001502499.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: slo:Shew_2470 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001502500.1 PFAM: protein of unknown function DUF885; KEGG: slo:Shew_2471 protein of unknown function DUF885 YP_001502501.1 PFAM: GGDEF domain containing protein; KEGG: slo:Shew_2472 diguanylate cyclase YP_001502502.1 SMART: Tetratricopeptide domain protein; KEGG: sfr:Sfri_2621 tetratricopeptide domain protein YP_001502503.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: slo:Shew_2474 TonB family protein YP_001502504.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: sbm:Shew185_1628 biopolymer transport protein ExbD/TolR YP_001502505.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: sbm:Shew185_1627 MotA/TolQ/ExbB proton channel YP_001502506.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: shn:Shewana3_2625 MotA/TolQ/ExbB proton channel YP_001502507.1 KEGG: saz:Sama_1254 hypothetical protein YP_001502508.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: xft:PD1283 TonB-dependent receptor YP_001502509.1 PFAM: porin Gram-negative type; KEGG: slo:Shew_2481 porin, gram-negative type YP_001502510.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_001502511.1 helicase involved in DNA repair and perhaps also replication YP_001502512.1 PFAM: protein of unknown function DUF81; KEGG: slo:Shew_2484 protein of unknown function DUF81 YP_001502513.1 KEGG: slo:Shew_2485 primosomal replication protein N'', putative YP_001502514.1 KEGG: she:Shewmr4_2473 hypothetical protein YP_001502515.1 PFAM: histone deacetylase superfamily; KEGG: she:Shewmr4_2474 histone deacetylase superfamily YP_001502516.1 KEGG: shn:Shewana3_2635 hypothetical protein YP_001502517.1 KEGG: slo:Shew_2489 competence protein ComEA helix-hairpin-helix repeat protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding class 1 YP_001502518.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: slo:Shew_2490 anion transporter YP_001502519.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: slo:Shew_2491 methionine gamma-lyase YP_001502520.1 PFAM: conserved hypothetical protein; KEGG: sbl:Sbal_1621 conserved hypothetical protein 1620 YP_001502521.1 PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: slo:Shew_2493 protein of unknown function DUF463, YcjX family protein YP_001502522.1 TIGRFAM: shock protein C; PFAM: PspC domain protein; KEGG: slo:Shew_2494 phage shock protein C, PspC YP_001502523.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_001502524.1 TIGRFAM: shock protein A; PFAM: PspA/IM30 family protein; KEGG: slo:Shew_2496 phage shock protein A, PspA YP_001502525.1 KEGG: slo:Shew_2497 sigma54 specific transcriptional regulator, fis family; TIGRFAM: Transcriptional activator PspF; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001502526.1 PFAM: extracellular solute-binding protein family 5; KEGG: slo:Shew_2498 extracellular solute-binding protein, family 5 YP_001502527.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_2499 binding-protein-dependent transport systems inner membrane component YP_001502528.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_2500 binding-protein-dependent transport systems inner membrane component YP_001502529.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; KEGG: spc:Sputcn32_1497 oligopeptide/dipeptide ABC transporter, ATPase subunit YP_001502530.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_2556 ABC transporter related YP_001502531.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_001502532.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: sbm:Shew185_1597 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001502533.1 PFAM: histone family protein DNA-binding protein; KEGG: sfr:Sfri_2593 histone family protein DNA-binding protein YP_001502534.1 KEGG: slo:Shew_2506 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16 lon domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001502535.1 binds and unfolds substrates as part of the ClpXP protease YP_001502536.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001502537.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001502538.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001502539.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001502540.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: slo:Shew_2512 peptidylprolyl isomerase YP_001502541.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_001502542.1 PFAM: tRNA--hydroxylase; KEGG: slo:Shew_2514 tRNA--hydroxylase YP_001502543.1 PFAM: protein of unknown function DUF1282; KEGG: shw:Sputw3181_2618 protein of unknown function DUF1282 YP_001502544.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001502545.1 TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; nucleoside recognition domain protein; KEGG: slo:Shew_2517 ferrous iron transport protein B YP_001502546.1 PFAM: FeoA family protein; KEGG: shw:Sputw3181_2621 FeoA family protein YP_001502547.1 TIGRFAM: cytochrome C family protein; PFAM: multihaem cytochrome; KEGG: slo:Shew_2519 cytochrome c family protein YP_001502548.1 KEGG: slo:Shew_2520 outer membrane protein, putative YP_001502549.1 KEGG: slo:Shew_2521 decaheme cytochrome c MtrF YP_001502550.1 KEGG: slo:Shew_2522 decaheme cytochrome c YP_001502551.1 KEGG: spc:Sputcn32_1479 hypothetical protein YP_001502552.1 KEGG: son:SO_1779 decaheme cytochrome c YP_001502553.1 KEGG: sfr:Sfri_2637 decaheme cytochrome c YP_001502554.1 TIGRFAM: cytochrome C family protein; PFAM: multihaem cytochrome; KEGG: slo:Shew_2526 cytochrome c family protein YP_001502555.1 KEGG: slo:Shew_2527 outer membrane protein precursor MtrB YP_001502556.1 KEGG: sbl:Sbal_1586 hypothetical protein YP_001502557.1 KEGG: saz:Sama_1203 hypothetical protein YP_001502558.1 PFAM: sugar diacid recognition domain protein; KEGG: slo:Shew_2528 transcriptional regulator, CdaR YP_001502559.1 KEGG: vch:VC0502 type IV pilin, putative YP_001502560.1 PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: vpa:VPA0248 putative outer membrane protein OmpA YP_001502561.1 KEGG: vha:VIBHAR_05979 hypothetical protein YP_001502562.1 KEGG: shm:Shewmr7_2311 hypothetical protein YP_001502563.1 KEGG: sbm:Shew185_0590 P pilus assembly protein porin PapC-like protein YP_001502566.1 KEGG: vha:VIBHAR_05990 hypothetical protein YP_001502567.1 KEGG: vha:VIBHAR_02615 hypothetical protein YP_001502568.1 PFAM: Gluconate transporter; Citrate transporter; KEGG: slo:Shew_2533 gluconate transporter YP_001502569.1 PFAM: glycerate kinase; KEGG: slo:Shew_2534 glycerate kinase YP_001502570.1 PFAM: Pyridoxal-dependent decarboxylase; KEGG: slo:Shew_2535 pyridoxal-dependent decarboxylase YP_001502571.1 KEGG: vpa:VP1633 putative RTX toxin YP_001502572.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: cps:CPS_4655 transcriptional regulator, AraC family YP_001502574.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mmw:Mmwyl1_1752 diguanylate cyclase/phosphodiesterase YP_001502575.1 PFAM: basic membrane lipoprotein; KEGG: hch:HCH_02309 uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein YP_001502578.1 KEGG: mmw:Mmwyl1_1032 hypothetical protein YP_001502579.1 PFAM: Lytic transglycosylase catalytic; KEGG: pha:PSHAb0242 putative transglycosylase YP_001502580.1 KEGG: vfi:VFA0327 hypothetical protein YP_001502581.1 KEGG: pha:PSHAb0243 putative orphan protein YP_001502582.1 PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: sbl:Sbal_1561 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I YP_001502583.1 PFAM: pseudouridine synthase; KEGG: sfr:Sfri_0787 pseudouridine synthase YP_001502584.1 PFAM: cytochrome B561; KEGG: slo:Shew_2692 cytochrome b561 YP_001502585.1 PFAM: Glutathione S-transferase domain; KEGG: sfr:Sfri_2500 glutathione S-transferase, C-terminal domain protein YP_001502586.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sfr:Sfri_2100 MscS mechanosensitive ion channel YP_001502587.1 KEGG: sbm:Shew185_1552 hypothetical protein YP_001502588.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: sfr:Sfri_1368 3-beta hydroxysteroid dehydrogenase/isomerase YP_001502589.1 Catalyzes the specific recognition and activation of amino acids during peptide synthesis YP_001502590.1 PFAM: alpha/beta hydrolase fold; KEGG: sbm:Shew185_1547 alpha/beta hydrolase fold YP_001502591.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001502592.1 KEGG: spc:Sputcn32_1444 hypothetical protein YP_001502593.1 KEGG: slo:Shew_1711 conserved hypothetical methyl-accepting chemotaxis protein YP_001502594.1 PFAM: protein of unknown function DUF1289; KEGG: slo:Shew_1710 protein of unknown function DUF1289 YP_001502595.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: slo:Shew_1709 HNH nuclease YP_001502596.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: sbm:Shew185_1542 choline/carnitine/betaine transporter YP_001502597.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_001502598.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001502599.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_1699 phosphate ABC transporter, inner membrane subunit PstA YP_001502600.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_1698 binding-protein-dependent transport systems inner membrane component YP_001502601.1 PFAM: amino acid-binding ACT domain protein; KEGG: slo:Shew_1697 amino acid-binding ACT domain protein YP_001502602.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sde:Sde_2463 response regulator receiver domain protein (CheY-like) YP_001502603.1 PFAM: regulatory protein LysR; KEGG: vco:VC0395_A0310 transcriptional regulator, LysR family YP_001502605.1 KEGG: vpa:VPA0990 hypothetical protein YP_001502606.1 PFAM: glycoside hydrolase family 16; KEGG: cac:CAC2807 endo-1,3(4)-beta-glucanase family 16 YP_001502607.1 KEGG: shn:Shewana3_2738 hypothetical protein YP_001502608.1 KEGG: shn:Shewana3_2741 hypothetical protein YP_001502609.1 PFAM: Thrombospondin type 3 repeat; peptidase domain protein; Peptidase M9A collagenase domain protein; Peptidase M9 domain; KEGG: slo:Shew_1685 microbial collagenase YP_001502610.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: slo:Shew_1684 lysine exporter protein (LysE/YggA) YP_001502611.1 PFAM: protein of unknown function DUF1415; KEGG: shw:Sputw3181_2672 protein of unknown function DUF1415 YP_001502612.1 PFAM: ribonuclease H; KEGG: sdn:Sden_0758 ribonuclease H YP_001502613.1 KEGG: slo:Shew_1678 hypothetical protein YP_001502614.1 PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: slo:Shew_1677 leucyl aminopeptidase YP_001502615.1 KEGG: slo:Shew_0274 hypothetical protein YP_001502616.1 PFAM: Modulator of Rho-dependent transcription termination; KEGG: vco:VC0395_0290 hypothetical protein YP_001502617.1 KEGG: tcx:Tcr_1988 hypothetical protein YP_001502618.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: ppr:PBPRB1458 putative NupC family protein (permease) YP_001502619.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: vfi:VFA0483 rod shape-determining protein RodA YP_001502620.1 PFAM: UspA domain protein; KEGG: vch:VCA0159 hypothetical protein YP_001502621.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ppr:PBPRA1446 putative lactoylglutathione lyase YP_001502622.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: vha:VIBHAR_04811 hypothetical protein YP_001502623.1 PFAM: major facilitator superfamily MFS_1; KEGG: vha:VIBHAR_04810 hypothetical protein YP_001502624.1 PFAM: AraC protein arabinose-binding/dimerisation; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: ppr:PBPRB0725 hypothetical protein YP_001502625.1 KEGG: rpd:RPD_2526 tetratricopeptide TPR_2 YP_001502626.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_1676 ABC transporter-related protein YP_001502627.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: shn:Shewana3_2761 copper-translocating P-type ATPase YP_001502628.1 TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: she:Shewmr4_2588 transcriptional regulator, MerR family YP_001502629.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: she:Shewmr4_2589 peptidase S9, prolyl oligopeptidase active site domain protein YP_001502630.1 KEGG: shw:Sputw3181_2696 hypothetical protein YP_001502631.1 KEGG: shn:Shewana3_2765 short-chain dehydrogenase/reductase SDR YP_001502632.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001502633.1 KEGG: slo:Shew_1672 3-hydroxyisobutyrate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding YP_001502634.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: slo:Shew_1671 enoyl-CoA hydratase/isomerase YP_001502635.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001502636.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: sbm:Shew185_1491 acyl-CoA dehydrogenase domain protein YP_001502637.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: spc:Sputcn32_1398 methylmalonate-semialdehyde dehydrogenase YP_001502638.1 KEGG: sdn:Sden_1943 acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase YP_001502639.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_001502640.1 KEGG: slo:Shew_2552 hypothetical protein YP_001502641.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: shw:Sputw3181_2708 short-chain dehydrogenase/reductase SDR YP_001502642.1 receptor for colicin S4 YP_001502644.1 PFAM: protein of unknown function DUF925; KEGG: she:Shewmr4_2602 protein of unknown function DUF925 YP_001502645.1 KEGG: son:SO_1913 hypothetical protein YP_001502646.1 KEGG: slo:Shew_2556 acyl-CoA thioesterase II; TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase YP_001502647.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: slo:Shew_2557 short-chain dehydrogenase/reductase SDR YP_001502648.1 TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; KEGG: slo:Shew_2558 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_001502649.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001502650.1 PFAM: AMP-dependent synthetase and ligase; KEGG: sbm:Shew185_2844 AMP-dependent synthetase and ligase YP_001502651.1 PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: slo:Shew_2569 transcriptional regulator, MerR family YP_001502652.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: slo:Shew_2570 acyl-CoA dehydrogenase domain protein YP_001502653.1 PFAM: carboxyl transferase; KEGG: sdn:Sden_2246 propionyl-CoA carboxylase YP_001502654.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: slo:Shew_2572 enoyl-CoA hydratase/isomerase YP_001502655.1 PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: slo:Shew_2573 carbamoyl-phosphate synthase L chain, ATP-binding YP_001502656.1 PFAM: pyruvate carboxyltransferase; KEGG: slo:Shew_2574 pyruvate carboxyltransferase YP_001502657.1 KEGG: slo:Shew_2575 3-oxoacid CoA-transferase, A subunit; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001502658.1 KEGG: slo:Shew_2576 3-oxoacid CoA-transferase, B subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001502659.1 PFAM: aminoglycoside phosphotransferase; KEGG: sdn:Sden_2943 aminoglycoside phosphotransferase YP_001502660.1 KEGG: shn:Shewana3_0471 hypothetical protein YP_001502661.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: mmw:Mmwyl1_1016 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family YP_001502662.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: rso:RSp0313 probable multidrug efflux system protein YP_001502663.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pfl:PFL_5111 DNA-binding response regulator ColR, putative YP_001502664.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sfr:Sfri_3675 periplasmic sensor signal transduction histidine kinase YP_001502665.1 KEGG: vfi:VF1339 hypothetical protein YP_001502666.1 PFAM: cytochrome c552; KEGG: shn:Shewana3_0658 cytochrome c552 YP_001502667.1 KEGG: sdn:Sden_2534 hypothetical protein YP_001502668.1 PFAM: Endoribonuclease L-PSP; KEGG: vfi:VFA0365 translation initiation inhibitor YP_001502669.1 KEGG: spc:Sputcn32_0630 hypothetical protein YP_001502670.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: sfr:Sfri_3126 cytoplasmic chaperone TorD family protein YP_001502671.1 TIGRFAM: Dimethylsulfoxide reductase chain B; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfr:Sfri_3683 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001502672.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: spc:Sputcn32_0627 anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family YP_001502673.1 KEGG: sfr:Sfri_3685 outer membrane protein YP_001502674.1 TIGRFAM: cytochrome C family protein; PFAM: multihaem cytochrome; KEGG: sfr:Sfri_3686 cytochrome c family protein YP_001502675.1 KEGG: cps:CPS_0255 isoprenylcysteine carboxyl methyltransferase family protein YP_001502676.1 PFAM: protein of unknown function DUF1176; protein of unknown function DUF1311; KEGG: par:Psyc_1081 hypothetical protein YP_001502679.1 KEGG: rba:RB8157 hypothetical protein YP_001502680.1 KEGG: dsy:DSY0956 hypothetical protein YP_001502681.1 PFAM: BRCT domain protein; leucine-rich repeat protein; KEGG: ana:alr0124 leucine-rich-repeat protein YP_001502682.1 KEGG: ana:alr0124 leucine-rich-repeat protein YP_001502683.1 KEGG: shm:Shewmr7_3723 hypothetical protein YP_001502685.1 KEGG: bam:Bamb_3528 hypothetical protein YP_001502686.1 KEGG: xcb:XC_1844 hypothetical protein YP_001502689.1 KEGG: mmz:MmarC7_1679 tetratricopeptide TPR_2 repeat protein YP_001502690.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: mgm:Mmc1_2003 Sel1 domain protein repeat-containing protein YP_001502692.1 PFAM: protein of unknown function DUF1568; KEGG: sdn:Sden_0135 protein of unknown function DUF1568 YP_001502693.1 PFAM: protein of unknown function DUF1568; KEGG: sdn:Sden_1610 protein of unknown function DUF1568 YP_001502694.1 KEGG: rha:RHA1_ro02516 possible hydrolase YP_001502695.1 KEGG: bur:Bcep18194_B3028 hypothetical protein YP_001502696.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: pfl:PFL_0213 TonB dependent receptor, putative YP_001502697.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rme:Rmet_2148 transcriptional regulator, LysR family YP_001502700.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: cps:CPS_0377 ISCps1, transposase YP_001502701.1 PFAM: LemA family protein; KEGG: ilo:IL1567 uncharacterized conserved membrane protein, LemA family YP_001502702.1 KEGG: ilo:IL1568 predicted membrane protein YP_001502703.1 KEGG: ilo:IL1568 predicted membrane protein YP_001502704.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_001502705.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: shn:Shewana3_1408 peptidase M3A and M3B, thimet/oligopeptidase F YP_001502706.1 PFAM: Na+/H+ antiporter NhaC; KEGG: slo:Shew_2582 Na+/H+ antiporter NhaC YP_001502707.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit ; Electron transfer flavoprotein alpha subunit; KEGG: slo:Shew_2583 electron transfer flavoprotein, alpha subunit YP_001502708.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: slo:Shew_2584 electron transfer flavoprotein beta-subunit YP_001502709.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: she:Shewmr4_1351 histone family protein nucleoid-structuring protein H-NS YP_001502710.1 PFAM: amidohydrolase; KEGG: slo:Shew_2586 amidohydrolase YP_001502711.1 KEGG: slo:Shew_2587 hypothetical protein YP_001502712.1 KEGG: shw:Sputw3181_1493 lipoprotein, putative YP_001502713.1 PFAM: protein of unknown function UPF0066; KEGG: sfr:Sfri_2751 protein of unknown function UPF0066 YP_001502714.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: son:SO_3152 acetyltransferase, CysE/LacA/LpxA/NodL family YP_001502715.1 PFAM: UspA domain protein; KEGG: slo:Shew_3100 UspA domain protein YP_001502716.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: pol:Bpro_3376 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001502717.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001502718.1 PFAM: Patatin; KEGG: saz:Sama_1160 hypothetical protein YP_001502719.1 KEGG: ppr:PBPRB1925 hypothetical protein YP_001502720.1 PFAM: TrkA-N domain protein; TrkA-C domain protein; sodium/hydrogen exchanger; KEGG: slo:Shew_2617 potassium efflux system protein YP_001502721.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sbl:Sbal_1467 diguanylate cyclase YP_001502722.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; Protein of unkown function DUF1946 PP-loop ATpase; KEGG: she:Shewmr4_2625 tRNA(Ile)-lysidine synthetase YP_001502723.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001502724.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001502725.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001502726.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001502727.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001502728.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001502729.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: slo:Shew_2626 outer membrane chaperone Skp (OmpH) YP_001502730.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: slo:Shew_2627 surface antigen (D15) YP_001502731.1 KEGG: shm:Shewmr7_2701 putative membrane-associated zinc metalloprotease; TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein YP_001502732.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001502733.1 PFAM: phosphatidate cytidylyltransferase; KEGG: saz:Sama_1144 phosphatidate cytidylyltransferase YP_001502734.1 KEGG: sbm:Shew185_1449 undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_001502735.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001502736.1 Catalyzes the phosphorylation of UMP to UDP YP_001502737.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001502738.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001502739.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001502740.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001502741.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001502742.1 KEGG: slo:Shew_2639 hypothetical protein YP_001502743.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001502744.1 PFAM: pseudouridine synthase; KEGG: slo:Shew_2643 pseudouridylate synthase YP_001502745.1 PFAM: protein of unknown function DUF446; KEGG: shm:Shewmr7_2718 protein of unknown function DUF446 YP_001502746.1 KEGG: shw:Sputw3181_2766 hypothetical protein YP_001502747.1 KEGG: slo:Shew_2646 hypothetical protein YP_001502748.1 KEGG: shn:Shewana3_2828 hypothetical protein YP_001502749.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sbl:Sbal_1437 GCN5-related N-acetyltransferase YP_001502750.1 KEGG: slo:Shew_2649 hypothetical protein YP_001502751.1 KEGG: sbl:Sbal_1435 hypothetical protein YP_001502752.1 KEGG: sfr:Sfri_1252 hypothetical protein YP_001502753.1 KEGG: slo:Shew_2652 hypothetical protein YP_001502754.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_001502755.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_001502756.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbl:Sbal_1430 transcriptional regulator, LysR family YP_001502757.1 PFAM: beta-lactamase domain protein; KEGG: sbl:Sbal_1429 beta-lactamase domain protein YP_001502758.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: sbm:Shew185_1421 4'-phosphopantetheinyl transferase YP_001502759.1 KEGG: slo:Shew_2664 transcriptional regulator, putative YP_001502760.1 KEGG: slo:Shew_2665 beta-ketoacyl synthase; TIGRFAM: Polyketide-type polyunsaturated fatty acid synthase, PfaA; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR domain protein; Beta-ketoacyl synthase ; Acyl transferase YP_001502761.1 TIGRFAM: PfaB family protein; KEGG: ppr:PBPRA1459 omega-3 polyunsaturated fatty acid synthase PfaB YP_001502762.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; Beta-ketoacyl synthase; KEGG: slo:Shew_2667 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ YP_001502763.1 TIGRFAM: PfaD family protein; KEGG: slo:Shew_2668 2-nitropropane dioxygenase, NPD YP_001502764.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; CHASE4 domain protein; KEGG: sdn:Sden_1662 GGDEF domain YP_001502765.1 KEGG: shw:Sputw3181_3641 hypothetical protein YP_001502766.1 PFAM: peptidase S45 penicillin amidase; KEGG: slo:Shew_2669 penicillin amidase YP_001502767.1 KEGG: sfr:Sfri_3228 hypothetical protein YP_001502768.1 KEGG: ppr:PBPRB0752 hypothetical protein YP_001502769.1 KEGG: abo:ABO_2640 dGTPase; TIGRFAM: putative deoxyguanosinetriphosphate triphosphohydrolase; SMART: metal-dependent phosphohydrolase HD region YP_001502770.1 KEGG: sfr:Sfri_0896 hypothetical protein YP_001502771.1 KEGG: sdn:Sden_2168 integrase, catalytic region YP_001502772.1 KEGG: ilo:IL1590 hypothetical protein YP_001502773.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mxa:MXAN_4597 putative methyltransferase YP_001502774.1 PFAM: protein of unknown function DUF1568; KEGG: sdn:Sden_0135 protein of unknown function DUF1568 YP_001502776.1 KEGG: cps:CPS_0689 hypothetical protein YP_001502777.1 KEGG: hch:HCH_03398 hypothetical protein YP_001502778.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: vfi:VF1790 ATP-dependent RNA helicase YP_001502779.1 KEGG: sfr:Sfri_0530 hypothetical protein YP_001502780.1 KEGG: sfr:Sfri_3605 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001502781.1 TIGRFAM: TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: son:SO_0719 TonB-dependent receptor, putative YP_001502782.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: shn:Shewana3_2944 TonB-dependent receptor YP_001502783.1 KEGG: slo:Shew_2693 hypothetical protein YP_001502784.1 PFAM: transposase IS116/IS110/IS902 family protein; KEGG: cps:CPS_0377 ISCps1, transposase YP_001502785.1 PFAM: protein of unknown function DUF1568; KEGG: shm:Shewmr7_1178 protein of unknown function DUF1568 YP_001502786.1 PFAM: Propeptide PepSY amd peptidase M4; KEGG: sfr:Sfri_1133 propeptide, PepSY amd peptidase M4 YP_001502787.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO_4647 DNA-binding response regulator YP_001502788.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; KEGG: pin:Ping_0281 sensor histidine kinase with ATPase domain YP_001502789.1 KEGG: sbm:Shew185_4214 hypothetical protein YP_001502790.1 SMART: tyrosine protein kinase; serine/threonine protein kinase; leucine-rich repeat-containing protein typical subtype; KEGG: shm:Shewmr7_0539 serine/threonine protein kinase YP_001502791.1 PFAM: protein of unknown function DUF599; KEGG: sbm:Shew185_0877 protein of unknown function DUF599 YP_001502792.1 KEGG: slo:Shew_2719 hypothetical protein YP_001502793.1 KEGG: shm:Shewmr7_2754 hypothetical protein YP_001502794.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_0630 conserved hypothetical protein 245 YP_001502795.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001502796.1 KEGG: sfr:Sfri_3204 nucleoside-diphosphate-sugar epimerase YP_001502797.1 PFAM: protein of unknown function DUF633; KEGG: sbm:Shew185_2328 hypothetical protein YP_001502798.1 PFAM: NUDIX hydrolase; KEGG: slo:Shew_2723 NUDIX hydrolase YP_001502799.1 KEGG: sde:Sde_0094 hypothetical protein YP_001502800.1 PFAM: sodium/glutamate symporter; KEGG: psa:PST_0687 sodium-glutamate symporter YP_001502801.1 PFAM: sodium:dicarboxylate symporter; KEGG: shw:Sputw3181_3503 sodium:dicarboxylate symporter YP_001502802.1 PFAM: Indigoidine synthase A family protein; KEGG: slo:Shew_2724 indigoidine synthase A family protein YP_001502803.1 PFAM: PfkB domain protein; Helix-turn-helix type 11 domain protein; KEGG: slo:Shew_2725 PfkB domain protein YP_001502804.1 TIGRFAM: YidE/YbjL duplication; PFAM: YidE/YbjL duplication domain protein; KEGG: vfi:VF1065 integral membrane protein with TrkA domains YP_001502805.1 TIGRFAM: glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; KEGG: vfi:VF1064 glutamate decarboxylase YP_001502806.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: sdn:Sden_2795 antibiotic biosynthesis monooxygenase YP_001502807.1 KEGG: cps:CPS_3943 hypothetical protein YP_001502808.1 KEGG: pat:Patl_1499 hypothetical protein YP_001502809.1 SMART: Dystroglycan-type cadherin domain protein; KEGG: vha:VIBHAR_00499 hypothetical protein YP_001502810.1 PFAM: protein of unknown function DUF188; KEGG: slo:Shew_2726 protein of unknown function DUF188 YP_001502811.1 PFAM: conserved hypothetical protein; KEGG: sbl:Sbal_1396 hypothetical protein YP_001502812.1 PFAM: Fmu (Sun) domain protein; KEGG: sfr:Sfri_1209 Fmu (Sun) domain protein YP_001502813.1 PFAM: GGDEF domain containing protein; Diverse 7TM receptor extracellular region 2; Diverse 7TM receptor transmembrane region; KEGG: shm:Shewmr7_2768 diguanylate cyclase YP_001502814.1 PFAM: YfaZ family protein; KEGG: slo:Shew_2740 YfaZ family protein YP_001502815.1 KEGG: slo:Shew_3409 putative lipoprotein YP_001502816.1 PFAM: glutathione peroxidase; KEGG: sfr:Sfri_2764 glutathione peroxidase YP_001502817.1 PFAM: peptidase M61 domain protein; Peptidase M1 membrane alanine aminopeptidase ; Leukotriene A4 hydrolase; KEGG: slo:Shew_2742 peptidase M1, membrane alanine aminopeptidase YP_001502818.1 PFAM: Peptidase M9A collagenase domain protein; KEGG: slo:Shew_2743 microbial collagenase YP_001502819.1 TIGRFAM: phosphate binding protein; KEGG: slo:Shew_2747 phosphate binding protein YP_001502820.1 KEGG: son:SO_1559 phosphate regulon sensor protein PhoR; TIGRFAM: Phosphate regulon sensor kinase PhoR; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001502821.1 TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: slo:Shew_2749 two component transcriptional regulator, winged helix family YP_001502822.1 PFAM: porin Gram-negative type; KEGG: slo:Shew_2750 porin, gram-negative type YP_001502823.1 Required for efficient pilin antigenic variation YP_001502824.1 PFAM: peptidase M61 domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: shn:Shewana3_2882 peptidase M61 domain protein YP_001502825.1 SMART: Tetratricopeptide domain protein; KEGG: son:SO_1552 TPR domain protein YP_001502826.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_2782 diguanylate cyclase YP_001502827.1 PFAM: conserved hypothetical protein; KEGG: sdn:Sden_2557 conserved hypothetical protein 730 YP_001502828.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_001502829.1 KEGG: slo:Shew_2757 hypothetical protein YP_001502830.1 PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: cte:CT0481 multiple antibiotic resistance protein YP_001502831.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; KEGG: she:Shewmr4_2719 peptidase S9, prolyl oligopeptidase active site domain protein YP_001502832.1 catalyzes the formation of 2-oxoglutarate from isocitrate YP_001502833.1 KEGG: slo:Shew_2761 hypothetical protein YP_001502834.1 PFAM: protein of unknown function DUF423; KEGG: slo:Shew_2762 protein of unknown function DUF423 YP_001502835.1 KEGG: slo:Shew_2763 dienelactone hydrolase YP_001502836.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_001502837.1 KEGG: slo:Shew_2765 hypothetical protein YP_001502838.1 Required for the synthesis of the thiazole moiety YP_001502839.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; Vibrio parahaemolyticus protein is associated with the polar flagella YP_001502840.1 Homologous to MotA in E. coli and Salmonella. With PomB forms the ion channels that couple flagellar rotation to sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. YP_001502841.1 TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII small subunit; KEGG: sbl:Sbal_1359 exodeoxyribonuclease VII, small subunit YP_001502842.1 PFAM: Polyprenyl synthetase; KEGG: slo:Shew_2770 polyprenyl synthetase YP_001502843.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001502844.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001502845.1 catalyzes the phosphorylation of NAD to NADP YP_001502846.1 PFAM: L-lactate permease; KEGG: slo:Shew_3135 L-lactate permease YP_001502847.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; FAD linked oxidase domain protein; KEGG: shn:Shewana3_2905 FAD linked oxidase domain protein YP_001502848.1 PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: slo:Shew_3004 protein of unknown function DUF224, cysteine-rich region domain protein YP_001502849.1 PFAM: protein of unknown function DUF162; KEGG: slo:Shew_3005 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001502850.1 PFAM: protein of unknown function DUF162; KEGG: shm:Shewmr7_2816 protein of unknown function DUF162 YP_001502851.1 TIGRFAM: TonB family protein; KEGG: son:SO_4043 TonB domain protein YP_001502852.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO_1506 MATE efflux family protein YP_001502853.1 PFAM: cobalamin synthesis protein P47K; KEGG: spc:Sputcn32_1255 cobalamin synthesis protein, P47K YP_001502854.1 KEGG: gsu:GSU0757 lipoprotein, putative YP_001502855.1 KEGG: vpa:VPA0754 hypothetical protein YP_001502856.1 KEGG: cps:CPS_2486 hypothetical protein YP_001502857.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: shw:Sputw3181_2850 DEAD/DEAH box helicase domain protein YP_001502858.1 KEGG: shn:Shewana3_2929 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001502859.1 PFAM: OsmC family protein; KEGG: shm:Shewmr7_1143 OsmC family protein YP_001502860.1 PFAM: thioesterase superfamily protein; KEGG: sbl:Sbal_3195 thioesterase superfamily protein YP_001502861.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: spc:Sputcn32_2800 diguanylate cyclase/phosphodiesterase YP_001502862.1 PFAM: Metal-dependent hydrolase HDOD; KEGG: saz:Sama_1005 putative signal transduction protein YP_001502863.1 PFAM: peptidase U32; KEGG: sfr:Sfri_1022 peptidase U32 YP_001502864.1 PFAM: Carbohydrate-selective porin OprB; KEGG: cps:CPS_0267 hypothetical protein YP_001502865.1 KEGG: vha:VIBHAR_05705 hypothetical protein YP_001502866.1 PFAM: amidohydrolase; KEGG: slo:Shew_0983 amidohydrolase YP_001502867.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ppr:PBPRB0224 hypothetical protein YP_001502868.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: slo:Shew_2785 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001502869.1 PFAM: pseudouridine synthase; KEGG: slo:Shew_2529 pseudouridine synthase YP_001502870.1 PFAM: Sterol-binding domain protein; KEGG: shw:Sputw3181_1208 sterol-binding domain protein YP_001502871.1 PFAM: peptidase U32; KEGG: slo:Shew_2787 peptidase U32 YP_001502872.1 PFAM: peptidase U32; KEGG: slo:Shew_2788 peptidase U32 YP_001502873.1 TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sfr:Sfri_3427 alcohol dehydrogenase GroES domain protein YP_001502874.1 KEGG: shn:Shewana3_1063 hypothetical protein YP_001502875.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; KEGG: shm:Shewmr7_2891 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor YP_001502876.1 PFAM: nucleoside recognition domain protein; KEGG: slo:Shew_2790 nucleoside recognition domain protein YP_001502877.1 PFAM: metallophosphoesterase; KEGG: sfr:Sfri_2266 metallophosphoesterase YP_001502878.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: slo:Shew_2795 xanthine/uracil/vitamin C permease YP_001502879.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: sbl:Sbal_1252 DEAD/DEAH box helicase domain protein YP_001502880.1 KEGG: hch:HCH_00820 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_001502881.1 KEGG: vfi:VF2363 glyceraldehyde 3-phosphate dehydrogenase YP_001502882.1 KEGG: vpa:VPA0078 hypothetical protein YP_001502883.1 PFAM: type IV pilus assembly PilZ; KEGG: shw:Sputw3181_1198 type IV pilus assembly PilZ YP_001502884.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001502885.1 PFAM: type IV pilus assembly PilZ; KEGG: slo:Shew_2808 type IV pilus assembly PilZ YP_001502886.1 KEGG: vco:VC0395_A1179 hypothetical protein YP_001502887.1 PFAM: SNARE associated Golgi protein; KEGG: vfi:VFA0471 DedA family protein YP_001502888.1 PFAM: sulfatase; KEGG: shw:Sputw3181_0059 sulfatase YP_001502889.1 PFAM: Polysulphide reductase NrfD; KEGG: shm:Shewmr7_0509 polysulphide reductase, NrfD YP_001502890.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: shn:Shewana3_3618 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001502891.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: sbm:Shew185_0531 molybdopterin oxidoreductase YP_001502892.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sbl:Sbal_3861 histidine kinase YP_001502893.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: shw:Sputw3181_3638 response regulator receiver protein YP_001502894.1 KEGG: slo:Shew_2809 alpha/beta hydrolase fold YP_001502895.1 KEGG: sbm:Shew185_3223 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase YP_001502896.1 KEGG: she:Shewmr4_1041 membrane protein YP_001502897.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_001502898.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_001502899.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_001502900.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001502901.1 PFAM: nucleoside-specific channel-forming protein Tsx; KEGG: son:SO_1215 outer membrane protein OmpK, putative YP_001502902.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: sbm:Shew185_3232 nucleoside transporter YP_001502903.1 PFAM: TatD-related deoxyribonuclease; KEGG: saz:Sama_0970 TatD-related deoxyribonuclease YP_001502904.1 KEGG: sbl:Sbal_3231 hypothetical protein YP_001502905.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001502906.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_001502907.1 KEGG: slo:Shew_2822 polyribonucleotide nucleotidyltransferase; PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH type 1 domain protein; Exoribonuclease, phosphorolytic domain 2; Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; SMART: KH domain protein YP_001502908.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase HAMP region domain protein; KEGG: sbm:Shew185_3276 diguanylate cyclase/phosphodiesterase YP_001502909.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001502910.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001502911.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001502912.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001502913.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001502914.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001502915.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: slo:Shew_2830 preprotein translocase, SecG subunit YP_001502916.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001502917.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001502918.1 KEGG: shm:Shewmr7_1085 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS YP_001502919.1 KEGG: slo:Shew_2834 ATP-dependent metalloprotease FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase central domain protein; peptidase M41 FtsH extracellular; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001502920.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_001502921.1 PFAM: protein of unknown function UPF0044; KEGG: slo:Shew_2836 protein of unknown function UPF0044 YP_001502922.1 TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF; PFAM: SecD/SecF/SecDF export membrane protein; KEGG: sbm:Shew185_3291 protein-export membrane protein SecF YP_001502923.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001502924.1 KEGG: sfr:Sfri_0978 hypothetical protein YP_001502925.1 TIGRFAM: transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: shn:Shewana3_1017 transcription elongation factor GreA YP_001502926.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001502927.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001502928.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001502929.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: slo:Shew_2841 peptidylprolyl isomerase, FKBP-type YP_001502930.1 PFAM: peptidase M48 Ste24p; KEGG: son:SO_1137 hypothetical protein YP_001502931.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001502932.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001502933.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: slo:Shew_2845 protein of unknown function DUF6, transmembrane YP_001502934.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3562 integrase, catalytic region YP_001502935.1 KEGG: sfr:Sfri_3563 transposase YP_001502936.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001502937.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001502938.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: saz:Sama_2517 xanthine/uracil permease family protein YP_001502939.1 KEGG: saz:Sama_1111 ATP-dependent endonuclease of the OLD family YP_001502940.1 KEGG: sbm:Shew185_3420 hypothetical protein YP_001502941.1 PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: spc:Sputcn32_0955 peptidase M17, leucyl aminopeptidase domain protein YP_001502942.1 KEGG: she:Shewmr4_0948 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001502943.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001502945.1 TIGRFAM: bacterioferritin; PFAM: Ferritin Dps family protein; KEGG: slo:Shew_2872 bacterioferritin YP_001502946.1 TIGRFAM: bacterioferritin; PFAM: Ferritin Dps family protein; KEGG: slo:Shew_2873 bacterioferritin YP_001502947.1 PFAM: protein of unknown function DUF539; KEGG: slo:Shew_2874 protein of unknown function DUF539 YP_001502948.1 PFAM: ApbE family lipoprotein; KEGG: she:Shewmr4_0942 ApbE family lipoprotein YP_001502949.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001502950.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_001502951.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_001502952.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001502953.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001502954.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001502955.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_001502956.1 PFAM: BolA family protein; KEGG: slo:Shew_2883 BolA family protein YP_001502957.1 KEGG: sbl:Sbal_0919 2OG-Fe(II) oxygenase YP_001502958.1 PFAM: methyltransferase small; ribosomal L11 methyltransferase; KEGG: shw:Sputw3181_3242 rRNA (guanine-N(2)-)-methyltransferase YP_001502959.1 PFAM: fatty acid hydroxylase; KEGG: sbm:Shew185_3594 sterol desaturase family protein YP_001502960.1 KEGG: slo:Shew_2888 hypothetical protein YP_001502961.1 PFAM: Uncharacterized lipoprotein; KEGG: slo:Shew_2889 uncharacterized lipoprotein YP_001502962.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: sfr:Sfri_3112 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001502963.1 KEGG: slo:Shew_2891 hypothetical protein YP_001502964.1 PFAM: major facilitator superfamily MFS_1; KEGG: slo:Shew_2892 major facilitator superfamily MFS_1 YP_001502965.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001502966.1 PFAM: VanZ family protein; KEGG: slo:Shew_2894 VanZ family protein YP_001502967.1 KEGG: slo:Shew_2895 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE domain protein YP_001502968.1 PFAM: sodium:neurotransmitter symporter; KEGG: ppr:PBPRA1510 putative sodium-dependent transporter YP_001502969.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: slo:Shew_2901 phosphoesterase, PA-phosphatase related YP_001502970.1 KEGG: sbl:Sbal_0704 hypothetical protein YP_001502971.1 PFAM: AbgT putative transporter; short chain fatty acid transporter; KEGG: saz:Sama_3423 transporter YP_001502972.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001502973.1 PFAM: protein of unknown function DUF819; KEGG: slo:Shew_2905 protein of unknown function DUF819 YP_001502974.1 KEGG: slo:Shew_2906 hypothetical protein YP_001502975.1 PFAM: Invasion gene expression up-regulator SirB; KEGG: son:SO_3830 hypothetical protein YP_001502976.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: slo:Shew_2911 modification methylase, HemK family YP_001502977.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001502978.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001502979.1 PFAM: outer membrane lipoprotein LolB; KEGG: sbm:Shew185_3616 outer membrane lipoprotein LolB YP_001502980.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001502981.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001502982.1 KEGG: slo:Shew_2917 hypothetical protein YP_001502983.1 KEGG: slo:Shew_2918 hypothetical protein YP_001502984.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001502985.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001502986.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: slo:Shew_2921 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family YP_001502987.1 KEGG: sbm:Shew185_3302 hypothetical protein YP_001502988.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001502989.1 PFAM: PhoH family protein; KEGG: slo:Shew_2924 PhoH family protein YP_001502990.1 PFAM: protein of unknown function UPF0054; KEGG: sdn:Sden_0813 protein of unknown function UPF0054 YP_001502991.1 PFAM: CBS domain containing protein; transporter-associated region; KEGG: slo:Shew_2926 CBS domain containing protein YP_001502992.1 Transfers the fatty acyl group on membrane lipoproteins YP_001502993.1 PFAM: protein of unknown function DUF1451; KEGG: slo:Shew_2928 protein of unknown function DUF1451 YP_001502994.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001502995.1 PFAM: Rare lipoprotein B; KEGG: shn:Shewana3_1000 rare lipoprotein B YP_001502996.1 KEGG: slo:Shew_2931 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta YP_001502997.1 KEGG: sfr:Sfri_0702 nicotinate (nicotinamide) nucleotide adenylyltransferase; TIGRFAM: cytidyltransferase-related domain; nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase YP_001502998.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: sbm:Shew185_3315 iojap-like protein YP_001502999.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001503000.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: slo:Shew_2935 peptidoglycan glycosyltransferase YP_001503001.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: slo:Shew_2936 rod shape-determining protein RodA YP_001503002.1 TIGRFAM: lytic murein transglycosylase B; KEGG: sbm:Shew185_3319 lytic murein transglycosylase B YP_001503003.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; Sporulation domain protein; KEGG: slo:Shew_2938 rare lipoprotein A YP_001503004.1 PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: slo:Shew_2939 serine-type D-Ala-D-Ala carboxypeptidase YP_001503005.1 PFAM: protein of unknown function DUF493; KEGG: shw:Sputw3181_1029 protein of unknown function DUF493 YP_001503006.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001503007.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001503008.1 TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_0987 ribosomal-protein-alanine acetyltransferase YP_001503009.1 KEGG: sfr:Sfri_0690 hypothetical protein YP_001503010.1 KEGG: sco:SCO0535 hydrolase (secreted protein) YP_001503011.1 KEGG: vha:VIBHAR_03714 hypothetical protein YP_001503012.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: sdn:Sden_3445 transposase IS116/IS110/IS902 YP_001503013.1 KEGG: sbl:Sbal_1020 hypothetical protein YP_001503014.1 KEGG: slo:Shew_2947 hypothetical protein YP_001503015.1 PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: slo:Shew_2948 ATPase AAA-2 domain protein YP_001503016.1 PFAM: protein of unknown function DUF152; KEGG: slo:Shew_2949 protein of unknown function DUF152 YP_001503017.1 KEGG: slo:Shew_2950 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001503018.1 KEGG: shm:Shewmr7_3075 putative lipoprotein YP_001503019.1 KEGG: vvu:VV1_2366 predicted exporter of the RND superfamily YP_001503020.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: shn:Shewana3_0764 methyl-accepting chemotaxis sensory transducer YP_001503021.1 catalyzes the formation of L-proline from L-ornithine YP_001503022.1 TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: slo:Shew_2956 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001503023.1 KEGG: shn:Shewana3_0762 hypothetical protein YP_001503024.1 KEGG: sfr:Sfri_0844 hypothetical protein YP_001503025.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_2959 transcriptional regulator, LysR family YP_001503026.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; protease-associated PA domain protein; KEGG: slo:Shew_2960 peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001503027.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: shw:Sputw3181_3383 pseudouridine synthase YP_001503028.1 PFAM: peptidase M13 neprilysin; peptidase M13; KEGG: slo:Shew_2973 endothelin-converting enzyme 1 YP_001503029.1 KEGG: she:Shewmr4_3180 hypothetical protein YP_001503030.1 KEGG: slo:Shew_2971 hypothetical protein YP_001503031.1 KEGG: slo:Shew_2970 hypothetical protein YP_001503032.1 PFAM: Glutathione S-transferase domain; KEGG: slo:Shew_2968 glutathione S-transferase, N-terminal domain YP_001503033.1 PFAM: membrane-flanked domain; KEGG: spc:Sputcn32_0787 membrane-flanked domain YP_001503034.1 KEGG: sbl:Sbal_0678 putative manganese transporter YP_001503035.1 PFAM: beta-lactamase; KEGG: son:SO_0914 hypothetical protein YP_001503036.1 PFAM: protein of unknown function DUF1456; KEGG: slo:Shew_2963 protein of unknown function DUF1456 YP_001503037.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_001503038.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: shw:Sputw3181_3558 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001503039.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: slo:Shew_0608 molybdopterin oxidoreductase YP_001503040.1 KEGG: sfr:Sfri_3147 transposase, IS4 family protein YP_001503041.1 KEGG: slo:Shew_2976 hypothetical protein YP_001503042.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: sbm:Shew185_3636 phosphoesterase PA-phosphatase related YP_001503043.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: slo:Shew_2977 diguanylate cyclase YP_001503044.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: slo:Shew_2977 diguanylate cyclase YP_001503045.1 TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: domain of unknown function DUF1730; KEGG: slo:Shew_2979 putative iron-sulfur cluster binding protein YP_001503046.1 PFAM: protein of unknown function DUF1458; KEGG: sfr:Sfri_0829 protein of unknown function DUF1458 YP_001503047.1 TIGRFAM: alkylhydroperoxidase-like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: afw:Anae109_3146 alkylhydroperoxidase-like protein, AhpD family YP_001503048.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ppr:PBPRB1577 hypothetical transcriptional regulator YP_001503049.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shw:Sputw3181_3956 redoxin domain protein YP_001503050.1 PFAM: DSBA oxidoreductase; KEGG: shw:Sputw3181_3957 DsbA oxidoreductase YP_001503051.1 PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: sbm:Shew185_4225 cytochrome c biogenesis protein transmembrane region YP_001503052.1 KEGG: shw:Sputw3181_3959 hypothetical protein YP_001503053.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001503054.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbm:Shew185_3641 transcriptional regulator, LysR family YP_001503055.1 PFAM: Metal-dependent hydrolase HDOD; KEGG: slo:Shew_2988 putative signal transduction protein YP_001503056.1 PFAM: lipolytic protein G-D-S-L family; KEGG: saz:Sama_2630 lipolytic enzyme, G-D-S-L YP_001503057.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: cps:CPS_1162 TonB-dependent vitamin B12 receptor YP_001503058.1 KEGG: sbl:Sbal_0662 hypothetical protein YP_001503059.1 PFAM: Penicillinase repressor; KEGG: slo:Shew_2994 transcriptional repressor, CopY family YP_001503060.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; peptidase M56 BlaR1; KEGG: slo:Shew_2995 TonB family protein YP_001503061.1 KEGG: cps:CPS_3036 hypothetical protein YP_001503062.1 PFAM: NADPH-dependent FMN reductase; KEGG: cps:CPS_1243 FMN reductase, NADPH-dependent YP_001503063.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: cps:CPS_1244 transcriptional regulator, LysR family YP_001503064.1 SMART: extracellular solute-binding protein family 3; KEGG: slo:Shew_3001 extracellular solute-binding protein, family 3 YP_001503065.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: mmw:Mmwyl1_1893 pseudouridine synthase YP_001503066.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001503067.1 KEGG: slo:Shew_2639 hypothetical protein YP_001503068.1 KEGG: slo:Shew_3002 hypothetical protein YP_001503069.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: slo:Shew_3008 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001503070.1 PFAM: glucose sorbosone dehydrogenase; KEGG: ppr:PBPRB1412 hypothetical glucose dehydrogenase YP_001503071.1 PFAM: protein of unknown function DUF1704; KEGG: slo:Shew_2900 protein of unknown function DUF1704 YP_001503072.1 The second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001503073.1 KEGG: slo:Shew_0733 hypothetical protein YP_001503074.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: vvy:VV2684 GGDEF family protein YP_001503075.1 TIGRFAM: putative outer membrane adhesin like proteiin; KEGG: prw:PsycPRwf_1167 putative outer membrane adhesin like proteiin YP_001503077.1 PFAM: LVIVD repeat protein YP_001503078.1 PFAM: ferredoxin-dependent glutamate synthase; SMART: zinc finger CDGSH-type domain protein; KEGG: vpa:VPA0765 putative glutamate synthetase YP_001503079.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); KEGG: sbl:Sbal_1573 HAD-superfamily hydrolase, subfamily IB (PSPase-like) YP_001503080.1 KEGG: sfr:Sfri_0910 UTP-GlnB uridylyltransferase, GlnD; TIGRFAM: protein-P-II uridylyltransferase; PFAM: amino acid-binding ACT domain protein; GlnD PII-uridylyltransferase YP_001503081.1 KEGG: sdn:Sden_2069 hypothetical protein YP_001503082.1 KEGG: pin:Ping_2245 hypothetical protein YP_001503083.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: slo:Shew_3327 RNA-metabolising metallo-beta-lactamase YP_001503084.1 KEGG: slo:Shew_2655 hypothetical protein YP_001503085.1 KEGG: ppr:PBPRB0452 hypothetical protein YP_001503086.1 PFAM: Curlin associated repeat protein; KEGG: sfr:Sfri_1516 curlin associated repeat protein YP_001503087.1 PFAM: band 7 protein; KEGG: slo:Shew_0978 band 7 protein YP_001503088.1 KEGG: vha:VIBHAR_05537 hypothetical protein YP_001503089.1 PFAM: PepSY-associated TM helix domain protein; KEGG: sde:Sde_2820 hypothetical protein YP_001503090.1 PFAM: peptidase M13 neprilysin; peptidase M13; KEGG: sfr:Sfri_1958 endothelin-converting enzyme 1 YP_001503091.1 YghU; B2989; one of eight putative glutathione transferase proteins from E. coli YP_001503092.1 PFAM: protein of unknown function DUF985; KEGG: spc:Sputcn32_3190 protein of unknown function DUF985 YP_001503093.1 KEGG: slo:Shew_3030 hypothetical protein YP_001503094.1 KEGG: vfi:VFA0969 guanine deaminase; TIGRFAM: Guanine deaminase; PFAM: amidohydrolase YP_001503095.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: aha:AHA_0949 xanthine/uracil permease family protein YP_001503096.1 PFAM: SpoOM family protein; KEGG: pha:PSHAa0857 SpoOM-related protein YP_001503097.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: rca:Rcas_3855 mandelate racemase/muconate lactonizing protein YP_001503098.1 PFAM: BCCT transporter; KEGG: oih:OB0704 choline transporter YP_001503099.1 PFAM: HI0933 family protein; FAD dependent oxidoreductase; KEGG: rpa:RPA2340 hypothetical protein YP_001503100.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: rru:Rru_A3003 transcriptional regulator, GntR family YP_001503101.1 KEGG: dme:Dmel_CG2839 CG2839 YP_001503102.1 PFAM: sodium/glutamate symporter; KEGG: slo:Shew_0103 sodium/glutamate symporter YP_001503103.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: vfi:VFA0117 transporter, drug/metabolite exporter family YP_001503104.1 PFAM: OsmC family protein; protein of unknown function DUF181; KEGG: sbl:Sbal_0643 protein of unknown function DUF181 YP_001503105.1 KEGG: sbm:Shew185_3665 hypothetical protein YP_001503106.1 PFAM: Ankyrin; KEGG: tva:TVAG_291510 ankyrin repeat protein, putative Pfam: Ank Clathrin PROSITE: ANK_REPEAT ANK_REP_REGION YP_001503107.1 KEGG: spc:Sputcn32_3202 hypothetical protein YP_001503108.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3340 integrase, catalytic region YP_001503109.1 KEGG: mmw:Mmwyl1_3491 transposase YP_001503110.1 PFAM: Na+/H+ antiporter NhaC; KEGG: asa:ASA_1781 Na+/H+ antiporter YP_001503111.1 KEGG: slo:Shew_1222 hypothetical protein YP_001503112.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: ppr:PBPRB1929 putative Cold shock-like protein YP_001503113.1 KEGG: vfi:VFA1093 hypothetical protein YP_001503114.1 KEGG: slo:Shew_2580 hypothetical protein YP_001503115.1 KEGG: son:SO_2929 hypothetical protein YP_001503116.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: aha:AHA_3197 methyl-accepting chemotaxis protein YP_001503117.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sdn:Sden_0245 GGDEF domain YP_001503118.1 KEGG: vfi:VF1097 BAX protein YP_001503119.1 KEGG: sdn:Sden_0849 hypothetical protein YP_001503120.1 PFAM: GCN5-related N-acetyltransferase; KEGG: fra:Francci3_3270 GCN5-related N-acetyltransferase YP_001503121.1 KEGG: vvu:VV2_0542 Mn2+ and Fe2+ transporter of the NRAMP family YP_001503122.1 PFAM: Citrate transporter; KEGG: ppr:PBPRB0793 putative Na+/H+ antiporter YP_001503124.1 KEGG: stp:Strop_2134 hypothetical protein YP_001503125.1 PFAM: sulfatase; KEGG: tbd:Tbd_0306 arylsulfatase YP_001503126.1 TIGRFAM: peptidase T-like protein; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: vfi:VFA0004 tripeptidase T YP_001503127.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: slo:Shew_3055 CMP/dCMP deaminase, zinc-binding YP_001503129.1 PFAM: cation antiporter; KEGG: sfr:Sfri_2281 cation antiporter YP_001503130.1 PFAM: multiple resistance and pH regulation protein F; KEGG: rru:Rru_A1640 multiple resistance and pH regulation protein F YP_001503131.1 TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; KEGG: hne:HNE_0731 monovalent cation/proton antiporter, MnhG/PhaG family YP_001503132.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001503133.1 PFAM: NADH-ubiquinone oxidoreductase chain 4L; KEGG: pla:Plav_2968 NADH-ubiquinone oxidoreductase chain 4L YP_001503134.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_001503135.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: pla:Plav_2966 NADH dehydrogenase (quinone) YP_001503136.1 KEGG: smd:Smed_3627 hypothetical protein YP_001503137.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; in S. meliloti it is known to be involved specifically with K+ transport YP_001503138.1 KEGG: bcz:BCZK0821 hypothetical protein YP_001503141.1 KEGG: vpa:VP1418 hypothetical protein YP_001503144.1 KEGG: cps:CPS_0790 hypothetical protein YP_001503145.1 PFAM: protein of unknown function DUF1568; KEGG: mfa:Mfla_0477 protein of unknown function DUF1568 YP_001503148.1 KEGG: shm:Shewmr7_0430 NTPase (NACHT family)-like protein YP_001503149.1 PFAM: protein of unknown function DUF1568; KEGG: shm:Shewmr7_1178 protein of unknown function DUF1568 YP_001503150.1 KEGG: slo:Shew_3059 hypothetical protein YP_001503151.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001503152.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001503153.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001503154.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: slo:Shew_3065 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family YP_001503155.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; 2-polyprenyl-6-methoxyphenol 4-hydroxylase; PFAM: monooxygenase FAD-binding; KEGG: slo:Shew_3066 2-polyprenyl-6-methoxyphenol 4-hydroxylase YP_001503156.1 TIGRFAM: yecA family protein; PFAM: protein of unknown function UPF0149; KEGG: shw:Sputw3181_0727 YecA family protein YP_001503158.1 PFAM: protein of unknown function DUF710; KEGG: slo:Shew_3068 protein of unknown function DUF710 YP_001503159.1 KEGG: ckl:CKL_1941 hypothetical protein YP_001503161.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: slo:Shew_3069 5-formyltetrahydrofolate cyclo-ligase YP_001503162.1 PFAM: protein of unknown function DUF1326; KEGG: cps:CPS_2422 hypothetical protein YP_001503163.1 KEGG: cps:CPS_2421 hypothetical protein YP_001503164.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001503165.1 KEGG: slo:Shew_3074 pilin, putative YP_001503166.1 KEGG: sfr:Sfri_3092 methylation site containing protein YP_001503167.1 KEGG: slo:Shew_3075 hypothetical protein YP_001503168.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: slo:Shew_3076 lysine exporter protein (LysE/YggA) YP_001503169.1 KEGG: sbl:Sbal_0960 thiol:disulfide interchange protein, putative YP_001503170.1 KEGG: she:Shewmr4_0887 transcriptional regulator, fis family; TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; AAA ATPase YP_001503171.1 TIGRFAM: Cytochrome c oxidase cbb3 type accessory protein FixG; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbl:Sbal_0957 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001503172.1 PFAM: AMP-dependent synthetase and ligase; KEGG: she:Shewmr4_0883 AMP-dependent synthetase and ligase YP_001503174.1 KEGG: slo:Shew_3087 lipid A ABC exporter family, fused ATPase and inner membrane subunits; TIGRFAM: lipid A ABC exporter family, fused ATPase and inner membrane subunits; PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001503175.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: shw:Sputw3181_3199 pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001503176.1 PFAM: protein of unknown function DUF1008; KEGG: spc:Sputcn32_0967 protein of unknown function DUF1008 YP_001503177.1 TIGRFAM: TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: shw:Sputw3181_3201 TonB-dependent heme/hemoglobin receptor family protein YP_001503178.1 TIGRFAM: TonB family protein; KEGG: sbm:Shew185_1020 TonB family protein YP_001503179.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: sbm:Shew185_1019 MotA/TolQ/ExbB proton channel YP_001503180.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: sbl:Sbal_0949 biopolymer transport protein ExbD/TolR YP_001503181.1 PFAM: periplasmic binding protein; KEGG: sbm:Shew185_1017 periplasmic binding protein YP_001503182.1 PFAM: transport system permease protein; KEGG: sbm:Shew185_1016 transport system permease protein YP_001503183.1 with HmuTU is involved in the transport of hemin YP_001503184.1 PFAM: regulatory protein TetR; KEGG: vfi:VF1676 hypothetical protein YP_001503185.1 PFAM: bifunctional deaminase-reductase domain protein; KEGG: vvu:VV2_1034 dihydrofolate reductase YP_001503186.1 PFAM: protein of unknown function DUF218; KEGG: bpe:BP2323 hypothetical protein YP_001503187.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: pha:PSHAb0015 putative transcriptional regulatory protein (LysR family) YP_001503188.1 PFAM: transmembrane pair domain protein; KEGG: vfi:VFA1143 hypothetical membrane spanning protein YP_001503189.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001503190.1 KEGG: vha:VIBHAR_03179 hypothetical protein YP_001503191.1 PFAM: periplasmic nitrate reductase NapE; KEGG: sbl:Sbal_3211 periplasmic nitrate reductase NapE YP_001503192.1 TIGRFAM: trimethylamine-N-oxide reductase c-type cytochrome TorC; PFAM: NapC/NirT cytochrome c domain protein; KEGG: son:SO_1233 tetraheme cytochrome c YP_001503193.1 TIGRFAM: trimethylamine-N-oxide reductase TorA; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfr:Sfri_1994 trimethylamine-N-oxide reductase TorA YP_001503194.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor YP_001503195.1 TIGRFAM: TMAO reductase sytem sensor TorS; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: sfr:Sfri_1992 multi-sensor hybrid histidine kinase YP_001503196.1 periplasmic sensory protein associated with the TorRS two-component regulatory system YP_001503197.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes YP_001503198.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_0030 hypothetical protein YP_001503199.1 PFAM: Ion transport protein; KEGG: pha:PSHAb0529 putative cation transporter component YP_001503200.1 KEGG: shw:Sputw3181_0969 hypothetical protein YP_001503201.1 PFAM: membrane-flanked domain; KEGG: slo:Shew_3091 membrane-flanked domain protein YP_001503202.1 PFAM: membrane-flanked domain; KEGG: slo:Shew_3092 membrane-flanked domain protein YP_001503203.1 PFAM: protein of unknown function DUF924; KEGG: sbl:Sbal_3327 protein of unknown function DUF924 YP_001503204.1 PFAM: UspA domain protein; KEGG: slo:Shew_3100 UspA domain protein YP_001503205.1 PFAM: UspA domain protein; KEGG: slo:Shew_3101 UspA domain protein YP_001503206.1 KEGG: slo:Shew_3102 hypothetical protein YP_001503207.1 PFAM: aldehyde dehydrogenase; KEGG: sbl:Sbal_3332 aldehyde dehydrogenase YP_001503208.1 PFAM: regulatory protein TetR; KEGG: slo:Shew_3104 transcriptional regulator, TetR family YP_001503209.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: PAS domain containing protein; KEGG: slo:Shew_0727 integral membrane sensor signal transduction histidine kinase YP_001503210.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: slo:Shew_0726 two component, sigma54 specific, transcriptional regulator, fis family YP_001503211.1 PFAM: protein of unknown function DUF214; KEGG: shm:Shewmr7_3157 protein of unknown function DUF214 YP_001503212.1 PFAM: protein of unknown function DUF214; KEGG: shm:Shewmr7_3158 protein of unknown function DUF214 YP_001503213.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sbm:Shew185_0998 ABC transporter related YP_001503214.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: slo:Shew_0721 efflux transporter, RND family, MFP subunit YP_001503215.1 PFAM: porin Gram-negative type; KEGG: slo:Shew_2283 porin, gram-negative type YP_001503216.1 PFAM: sigma-54 factor interaction domain-containing protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: slo:Shew_2282 transcriptional regulator, fis family YP_001503217.1 KEGG: slo:Shew_2281 flavocytochrome c; TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase YP_001503218.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: slo:Shew_2280 phenylalanine/histidine ammonia-lyase YP_001503219.1 KEGG: slo:Shew_2279 tetraheme cytochrome c YP_001503220.1 KEGG: shn:Shewana3_3269 hypothetical protein YP_001503221.1 KEGG: ppr:PBPRB0735 hypothetical protein YP_001503222.1 KEGG: mma:MM_0051 hypothetical protein YP_001503223.1 PFAM: periplasmic binding protein; KEGG: shn:Shewana3_3272 periplasmic binding protein YP_001503225.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001503226.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_001503227.1 PFAM: cobalbumin biosynthesis protein; KEGG: shn:Shewana3_3276 cobalbumin biosynthesis enzyme YP_001503228.1 TIGRFAM: cobalamin 5'-phosphate synthase; PFAM: cobalamin-5-phosphate synthase CobS; KEGG: son:SO_1036 cobalamin 5'-phosphate synthase YP_001503229.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001503230.1 PFAM: transport system permease protein; KEGG: slo:Shew_0713 transport system permease protein YP_001503231.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_0712 ABC transporter-related protein YP_001503232.1 PFAM: Phosphoglycerate mutase; KEGG: slo:Shew_0711 phosphoglycerate mutase YP_001503233.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_001503234.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: saz:Sama_1252 TonB-dependent receptor YP_001503236.1 catalyzes the reaction of formaldehyde with glutathione to form S-hydroxymethylglutathione YP_001503237.1 KEGG: gfo:GFO_0080 FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_001503239.1 PFAM: MscS Mechanosensitive ion channel; KEGG: vvu:VV1_0007 small-conductance mechanosensitive channel YP_001503240.1 KEGG: sdn:Sden_0577 hypothetical protein YP_001503241.1 catalyzes the formation of inosine from adenosine YP_001503242.1 PFAM: TM2 domain containing protein?; KEGG: ppd:Ppro_2995 TM2 domain containing protein+B7201 YP_001503243.1 KEGG: shn:Shewana3_0174 hypothetical protein YP_001503244.1 PFAM: RDD domain containing protein; KEGG: shm:Shewmr7_2450 RDD domain containing protein YP_001503245.1 PFAM: extracellular solute-binding protein family 3; KEGG: son:SO_1044 amino acid ABC transporter, periplasmic amino acid-binding protein YP_001503246.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_3165 polar amino acid ABC transporter, inner membrane subunit YP_001503247.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_3164 ABC transporter-related protein YP_001503248.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: csa:Csal_1337 transcriptional regulator, LysR family YP_001503249.1 PFAM: S-adenosyl-L-homocysteine hydrolase; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; alanine dehydrogenase/PNT domain protein; Acetohydroxy acid isomeroreductase catalytic domain protein; S-adenosyl-L-homocysteine hydrolase, NAD binding; KEGG: mja:MJ1388 S-adenosyl-L-homocysteine hydrolase YP_001503250.1 PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: slo:Shew_0707 YbaK/prolyl-tRNA synthetase associated region YP_001503251.1 KEGG: shw:Sputw3181_2912 hypothetical protein YP_001503252.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: son:SO_4295 NAD(P)H dehydrogenase (quinone) YP_001503253.1 PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: son:SO_4296 NupC family protein YP_001503254.1 KEGG: ppr:PBPRB0398 hypothetical protein YP_001503255.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: slo:Shew_0490 peptidase S9, prolyl oligopeptidase active site domain protein YP_001503256.1 PFAM: protein of unknown function DUF805; KEGG: cte:CT1580 aminopeptidase C, putative YP_001503258.1 KEGG: fnu:FN2119 hypothetical exported 24-amino acid repeat protein YP_001503259.1 PFAM: Choloylglycine hydrolase; KEGG: sdn:Sden_0442 choloylglycine hydrolase YP_001503260.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sdn:Sden_0443 GGDEF domain YP_001503261.1 KEGG: sbm:Shew185_3407 hypothetical protein YP_001503262.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: slo:Shew_2195 NADH dehydrogenase YP_001503263.1 KEGG: vha:VIBHAR_04801 hypothetical protein YP_001503265.1 KEGG: sbm:Shew185_1422 lipoprotein, putative YP_001503266.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: mmw:Mmwyl1_4378 helix-turn-helix-domain containing protein AraC type YP_001503267.1 PFAM: major facilitator superfamily MFS_1; KEGG: mms:mma_1047 transporter of the MFS superfamily YP_001503268.1 KEGG: ppr:PBPRB1341 hypothetical protein YP_001503269.1 PFAM: secretion protein HlyD family protein; KEGG: ppr:PBPRB1340 putative secretion protein YP_001503270.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ppr:PBPRB1339 hypothetical transcriptional regulator YP_001503271.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdn:Sden_1874 GCN5-related N-acetyltransferase YP_001503272.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: shw:Sputw3181_2351 TonB-dependent receptor YP_001503273.1 PFAM: Na+/H+ antiporter NhaC; KEGG: slo:Shew_0698 Na+/H+ antiporter NhaC YP_001503274.1 KEGG: sbl:Sbal_3290 hypothetical protein YP_001503275.1 PFAM: permease; KEGG: vha:VIBHAR_05267 hypothetical protein YP_001503276.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: vfi:VF1072 transcriptional regulators, LysR family YP_001503277.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_2959 transcriptional regulator, LysR family YP_001503278.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; protease-associated PA domain protein; KEGG: slo:Shew_0807 peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001503279.1 PFAM: protein of unknown function DUF331; KEGG: slo:Shew_0695 protein of unknown function DUF331 YP_001503280.1 KEGG: mfa:Mfla_2466 hypothetical protein YP_001503281.1 PFAM: 3'-5' exonuclease; KEGG: shm:Shewmr7_1014 3'-5' exonuclease YP_001503283.1 KEGG: shw:Sputw3181_2350 hypothetical protein YP_001503284.1 KEGG: sfr:Sfri_3634 hypothetical protein YP_001503285.1 KEGG: sfr:Sfri_3633 cytochrome c, putative YP_001503286.1 PFAM: transcriptional regulator domain protein; KEGG: sfr:Sfri_3632 response regulator receiver protein YP_001503287.1 KEGG: sfr:Sfri_3631 hypothetical protein YP_001503288.1 KEGG: slo:Shew_0689 hypothetical protein YP_001503289.1 PFAM: DSBA oxidoreductase; KEGG: sbm:Shew185_0941 DsbA oxidoreductase YP_001503290.1 PFAM: glycosyl transferase group 1; KEGG: ana:all2291 glycosyltransferase YP_001503291.1 KEGG: spc:Sputcn32_0803 hypothetical protein YP_001503292.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_001503293.1 PFAM: peptidase M16 domain protein; KEGG: shn:Shewana3_0842 peptidase M16 domain protein YP_001503294.1 PFAM: peptidase M16 domain protein; KEGG: shn:Shewana3_0841 peptidase M16 domain protein YP_001503295.1 PFAM: StbA family protein; KEGG: ppr:PBPRA0050 hypothetical StbA plasmid stable inheritance protein YP_001503296.1 KEGG: ppr:PBPRA0051 hypothetical protein YP_001503297.1 catalyzes the formation of pyruvate from serine YP_001503298.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_001503299.1 regulates the synthesis and expression of the dsdXA operon and dadA gene YP_001503300.1 KEGG: slo:Shew_0631 AFG1-family ATPase YP_001503302.1 e14 prophage; cell death peptidase; inhibitor of T4 late gene expression; late inhibitor of T4 YP_001503303.1 KEGG: aba:Acid345_3545 hypothetical protein YP_001503305.1 PFAM: helix-turn-helix domain protein; KEGG: sfr:Sfri_3420 transcriptional regulator, XRE family protein YP_001503306.1 KEGG: sbm:Shew185_4272 hypothetical protein YP_001503307.1 PFAM: helicase domain protein; type III restriction protein res subunit; KEGG: sbm:Shew185_4273 type III restriction protein res subunit YP_001503308.1 KEGG: shn:Shewana3_1253 hypothetical protein YP_001503311.1 PFAM: integrase family protein; KEGG: vch:VC0183 hypothetical protein YP_001503313.1 PFAM: integrase family protein; KEGG: spc:Sputcn32_0163 hypothetical protein YP_001503314.1 PFAM: AFG1-family ATPase; KEGG: slo:Shew_0631 AFG1-family ATPase YP_001503315.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: sdn:Sden_3445 transposase IS116/IS110/IS902 YP_001503316.1 KEGG: sfr:Sfri_2004 hypothetical protein YP_001503317.1 KEGG: mmz:MmarC7_1679 tetratricopeptide TPR_2 repeat protein YP_001503319.1 KEGG: bbt:BBta_4307 putative membrane protein of unknown function YP_001503320.1 KEGG: vha:VIBHAR_01968 hypothetical protein YP_001503323.1 KEGG: vvy:VV2395 hypothetical protein YP_001503324.1 KEGG: cph:Cpha266_2334 lipase, class 3 YP_001503325.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001503326.1 KEGG: slo:Shew_0627 hypothetical protein YP_001503327.1 KEGG: slo:Shew_0626 protein of unknown function DUF350 YP_001503328.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001503329.1 KEGG: slo:Shew_0624 hypothetical protein YP_001503330.1 PFAM: PspA/IM30 family protein; KEGG: sdn:Sden_0697 PspA/IM30 YP_001503331.1 KEGG: shm:Shewmr7_0857 hypothetical protein YP_001503332.1 KEGG: slo:Shew_0621 hypothetical protein YP_001503333.1 PFAM: Ion transport protein; Ion transport 2 domain protein; KEGG: son:SO_3768 ion transporter YP_001503334.1 PFAM: adenylate cyclase; KEGG: slo:Shew_0619 adenylate cyclase YP_001503335.1 PFAM: protein of unknown function DUF47; KEGG: slo:Shew_0618 protein of unknown function DUF47 YP_001503336.1 PFAM: phosphate transporter; KEGG: slo:Shew_0617 phosphate transporter YP_001503337.1 PFAM: SH3 type 3 domain protein; SMART: SH3 domain protein; KEGG: slo:Shew_0616 SH3 domain protein YP_001503338.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain YP_001503339.1 PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: ppr:PBPRA3375 putative methyl-accepting chemotaxis protein YP_001503340.1 PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: ppr:PBPRA3375 putative methyl-accepting chemotaxis protein YP_001503341.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001503342.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001503343.1 KEGG: slo:Shew_0605 hypothetical protein YP_001503344.1 KEGG: sdn:Sden_1261 hypothetical protein YP_001503345.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: slo:Shew_0604 DEAD/DEAH box helicase domain protein YP_001503346.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_001503347.1 KEGG: dvl:Dvul_0140 lipoprotein, putative YP_001503348.1 PFAM: conserved hypothetical protein; KEGG: shw:Sputw3181_0827 hypothetical protein YP_001503349.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shw:Sputw3181_0826 ABC transporter related YP_001503350.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_0592 hypothetical protein YP_001503351.1 PFAM: glucose-methanol-choline oxidoreductase; KEGG: slo:Shew_0591 glucose-methanol-choline oxidoreductase YP_001503352.1 KEGG: slo:Shew_0590 hypothetical protein YP_001503353.1 PFAM: alpha/beta hydrolase fold; KEGG: shm:Shewmr7_3286 alpha/beta hydrolase fold YP_001503354.1 PFAM: protein of unknown function UPF0270; KEGG: saz:Sama_3001 protein of unknown function UPF0270 YP_001503355.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: slo:Shew_0587 phosphoribulokinase YP_001503356.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: sbl:Sbal_0579 Sel1 domain protein repeat-containing protein YP_001503357.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_001503358.1 KEGG: shn:Shewana3_0616 hypothetical protein YP_001503359.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: slo:Shew_0583 two component transcriptional regulator, winged helix family YP_001503360.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: slo:Shew_0582 integral membrane sensor signal transduction histidine kinase YP_001503361.1 KEGG: shw:Sputw3181_3526 hypothetical protein YP_001503362.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_001503363.1 PFAM: arginine N-succinyltransferase beta subunit; KEGG: slo:Shew_0579 arginine N-succinyltransferase YP_001503364.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_001503365.1 PFAM: Metal-dependent hydrolase HDOD; KEGG: shn:Shewana3_0608 putative signal transduction protein YP_001503366.1 PFAM: peptidase S15; peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9B dipeptidylpeptidase IV domain protein; KEGG: slo:Shew_0576 peptidase S9, prolyl oligopeptidase active site domain protein YP_001503367.1 TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: shn:Shewana3_0606 glutamine amidotransferase of anthranilate synthase YP_001503368.1 KEGG: dps:DP2970 hypothetical protein YP_001503369.1 TIGRFAM: TonB family protein; KEGG: dps:DP2971 similar to TonB protein YP_001503370.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: dps:DP2972 biopolymer transport protein (ExbD2) YP_001503371.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: vpa:VPA0153 TonB system transport protein ExbB2 YP_001503372.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: dps:DP2974 similar to transport protein TolQ YP_001503373.1 KEGG: dps:DP2975 hypothetical protein YP_001503374.1 KEGG: dps:DP2976 hypothetical protein YP_001503375.1 KEGG: dps:DP2977 hypothetical protein YP_001503376.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: dps:DP2978 related to iron (III) ABC transporter, ATP-binding protein YP_001503377.1 PFAM: transport system permease protein; KEGG: dps:DP2979 probable iron (III) ABC transporter, permease protein YP_001503378.1 PFAM: periplasmic binding protein; KEGG: dps:DP2980 probable iron (III) ABC transporter, periplasmic-binding protein YP_001503379.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: dps:DP2981 related to TonB dependent outer membrane receptor YP_001503380.1 PFAM: Stringent starvation protein B; KEGG: slo:Shew_0574 stringent starvation protein B YP_001503381.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_001503382.1 PFAM: cytochrome c1; KEGG: saz:Sama_3019 ubiquinol-cytochrome c reductase cytochrome c1 subunit YP_001503383.1 PFAM: Cytochrome b/b6 domain; KEGG: slo:Shew_0571 cytochrome b/b6, N-terminal domain YP_001503384.1 KEGG: slo:Shew_0570 ubiquinol-cytochrome c reductase, iron-sulfur subunit; TIGRFAM: ubiquinol-cytochrome c reductase, iron-sulfur subunit; PFAM: Rieske [2Fe-2S] domain protein YP_001503385.1 TIGRFAM: HflC protein; PFAM: band 7 protein; KEGG: shn:Shewana3_0600 HflC protein YP_001503386.1 TIGRFAM: HflK protein; PFAM: band 7 protein; KEGG: sbm:Shew185_3765 HflK protein YP_001503387.1 TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; KEGG: slo:Shew_0567 GTP-binding protein, HSR1-related YP_001503388.1 TIGRFAM: RNA chaperone Hfq; PFAM: Like-Sm ribonucleoprotein core; KEGG: slo:Shew_0566 RNA chaperone Hfq YP_001503389.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001503390.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001503391.1 PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: slo:Shew_0563 N-acetylmuramoyl-L-alanine amidase YP_001503392.1 PFAM: protein of unknown function UPF0079; KEGG: shn:Shewana3_0593 protein of unknown function UPF0079 YP_001503393.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family domain protein; KEGG: spc:Sputcn32_3285 carbohydrate kinase, YjeF related protein YP_001503394.1 KEGG: saz:Sama_3031 hypothetical protein YP_001503395.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001503396.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001503397.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_001503398.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sbl:Sbal_0548 protein of unknown function DUF6, transmembrane YP_001503399.1 PFAM: MscS Mechanosensitive ion channel; KEGG: slo:Shew_0555 MscS mechanosensitive ion channel YP_001503400.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: she:Shewmr4_0586 glycerophosphoryl diester phosphodiesterase YP_001503401.1 KEGG: son:SO_0586 hypothetical protein YP_001503402.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: slo:Shew_0553 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001503403.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: shn:Shewana3_0581 BFD domain protein (2Fe-2S)-binding domain protein YP_001503404.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001503405.1 KEGG: slo:Shew_0550 L-sorbosone dehydrogenase, putative YP_001503406.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001503407.1 PFAM: protein of unknown function UPF0227; KEGG: slo:Shew_0548 protein of unknown function UPF0227 YP_001503408.1 PFAM: metallophosphoesterase; Calcineurin phosphoesterase domain protein; KEGG: shm:Shewmr7_0756 calcineurin phosphoesterase C-terminal domain protein YP_001503409.1 PFAM: protein of unknown function DUF1249; KEGG: shw:Sputw3181_3405 protein of unknown function DUF1249 YP_001503410.1 PFAM: NUDIX hydrolase; KEGG: slo:Shew_0545 ADP-ribose diphosphatase YP_001503411.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_001503412.1 KEGG: sbm:Shew185_0780 hypothetical protein YP_001503413.1 KEGG: slo:Shew_0542 hypothetical protein YP_001503414.1 PFAM: protein of unknown function DUF461; KEGG: spc:Sputcn32_0765 protein of unknown function DUF461 YP_001503415.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: shn:Shewana3_0721 enoyl-CoA hydratase/isomerase YP_001503416.1 PFAM: PspC domain protein; KEGG: slo:Shew_0538 phage shock protein C, PspC YP_001503417.1 KEGG: slo:Shew_0537 hypothetical protein YP_001503418.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase DuS; KEGG: slo:Shew_0536 TIM-barrel protein, YjbN family YP_001503419.1 PFAM: regulatory protein LysR; KEGG: shw:Sputw3181_3897 transcriptional regulator, LysR family YP_001503420.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbl:Sbal_0179 transcriptional regulator, LysR family YP_001503421.1 KEGG: son:SO_1779 decaheme cytochrome c YP_001503422.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FMN-binding domain protein; KEGG: shw:Sputw3181_0118 flavocytochrome c YP_001503423.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: spc:Sputcn32_2431 phenylalanine/histidine ammonia-lyase YP_001503424.1 PFAM: histidine kinase A domain protein; KEGG: shn:Shewana3_4006 histidine kinase A domain protein YP_001503425.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO_4623 DNA-binding response regulator YP_001503426.1 PFAM: regulatory protein LuxR; KEGG: son:SO_4624 transcriptional regulator, LuxR family YP_001503427.1 KEGG: slo:Shew_3276 hypothetical protein YP_001503428.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001503429.1 KEGG: slo:Shew_3278 replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; SMART: AAA ATPase YP_001503430.1 KEGG: slo:Shew_3279 hypothetical protein YP_001503431.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001503432.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001503433.1 binds single-stranded DNA at the primosome assembly site YP_001503434.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001503435.1 PFAM: protein of unknown function DUF481; KEGG: sbm:Shew185_0710 protein of unknown function DUF481 YP_001503436.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: sfr:Sfri_3635 prolyl oligopeptidase YP_001503437.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_001503438.1 KEGG: slo:Shew_3289 ribonuclease R; TIGRFAM: VacB and RNase II family 3'-5' exoribonuclease; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; Ribonuclease B OB region domain; Ribonuclease R winged-helix domain protein; SMART: Cold shock protein YP_001503439.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: slo:Shew_3290 Sel1 domain protein repeat-containing protein YP_001503440.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001503441.1 KEGG: slo:Shew_3292 hypothetical protein YP_001503442.1 forms a direct contact with the tRNA during translation YP_001503443.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001503444.1 PFAM: AFG1-family ATPase; KEGG: slo:Shew_3295 AFG1-family ATPase YP_001503446.1 KEGG: slo:Shew_3296 protease Do; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001503447.1 KEGG: son:SO_3943 protease DegS; TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001503448.1 KEGG: ppd:Ppro_3498 hypothetical protein YP_001503449.1 PFAM: response regulator receiver; KEGG: vha:VIBHAR_05158 hypothetical protein YP_001503450.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: vha:VIBHAR_05159 hypothetical protein YP_001503451.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001503452.1 PFAM: BolA family protein; KEGG: slo:Shew_3299 BolA family protein YP_001503453.1 KEGG: shn:Shewana3_0682 SpoIIAA family protein YP_001503454.1 PFAM: toluene tolerance family protein; KEGG: sbl:Sbal_3659 toluene tolerance family protein YP_001503455.1 PFAM: Mammalian cell entry related domain protein; KEGG: shw:Sputw3181_3450 mammalian cell entry related domain protein YP_001503456.1 PFAM: protein of unknown function DUF140; KEGG: slo:Shew_3303 protein of unknown function DUF140 YP_001503457.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_3304 ABC transporter-related protein YP_001503458.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: slo:Shew_3305 Na+/Ca+ antiporter, CaCA family YP_001503459.1 KEGG: slo:Shew_3306 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_001503460.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_001503461.1 PFAM: protein of unknown function DUF1239; KEGG: slo:Shew_3308 protein of unknown function DUF1239 YP_001503462.1 TIGRFAM: Cell envelope biogenesis YhbN; PFAM: OstA family protein; KEGG: slo:Shew_3309 OstA family protein YP_001503463.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_3310 ABC transporter-related protein YP_001503464.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001503465.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: saz:Sama_3089 ribosomal subunit interface protein YP_001503466.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: slo:Shew_3313 PTS IIA-like nitrogen-regulatory protein PtsN YP_001503467.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: shw:Sputw3181_3462 phosphotransferase system, phosphocarrier protein HPr YP_001503468.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: slo:Shew_3316 magnesium transporter YP_001503469.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; KEGG: slo:Shew_2687 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_001503470.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen; KEGG: slo:Shew_0908 OmpA/MotB domain protein YP_001503471.1 KEGG: spc:Sputcn32_0707 transposase IS3/IS911 family protein YP_001503472.1 KEGG: cps:CPS_0069 putative FG-GAP repeat lipoprotein YP_001503473.1 PFAM: GtrA family protein YP_001503474.1 PFAM: glycosyl transferase family 39; KEGG: vha:VIBHAR_02790 hypothetical protein YP_001503475.1 PFAM: glycosyl transferase family 2; KEGG: vha:VIBHAR_02791 hypothetical protein YP_001503476.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: slo:Shew_3317 two component transcriptional regulator, winged helix family YP_001503477.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: slo:Shew_3318 integral membrane sensor signal transduction histidine kinase YP_001503478.1 PFAM: Protein of unknown function DUF676 hydrolase domain protein; PGAP1 family protein; KEGG: slo:Shew_3323 lipase-like YP_001503479.1 KEGG: sbl:Sbal_2332 hypothetical protein YP_001503480.1 PFAM: major facilitator superfamily MFS_1; KEGG: pha:PSHAa1259 transport protein of the major facilitator YP_001503481.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_001503482.1 PFAM: TOBE domain protein; KEGG: slo:Shew_3338 TOBE domain protein YP_001503484.1 KEGG: shw:Sputw3181_3482 hypothetical protein YP_001503485.1 PFAM: protein of unknown function DUF134; KEGG: shw:Sputw3181_3483 protein of unknown function DUF134 YP_001503486.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: vfi:VF0677 putative dipeptide ABC transporter YP_001503487.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: vfi:VF0678 oligopeptide transport ATP-binding protein OppD YP_001503488.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: vfi:VF0679 oligopeptide transport system permease protein OppC YP_001503489.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: aha:AHA_2519 ABC nickel/di-oligopepetide transporter, permease subunit YP_001503490.1 PFAM: extracellular solute-binding protein family 5; KEGG: vfi:VF0681 oligopeptide-binding protein OppA YP_001503491.1 PFAM: CopG domain protein DNA-binding domain protein; NikR nickel binding; KEGG: ccv:CCV52592_1897 NikR C nickel binding domain family YP_001503492.1 PFAM: protein of unknown function DUF1275; KEGG: mmw:Mmwyl1_2095 protein of unknown function DUF1275 YP_001503493.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: ppr:PBPRA1266 putative peptidyl-prolyl cis-trans isomerase B YP_001503494.1 PFAM: aminotransferase class V; KEGG: ppr:PBPRB0227 putative ScrA YP_001503495.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: ppr:PBPRB0229 hypothetical ScrC (sensory box/GGDEF familyprotein) (involved in swarmer cell regulation) YP_001503496.1 SMART: extracellular solute-binding protein family 3; KEGG: ppr:PBPRB0228 putative ScrB YP_001503497.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase YP_001503498.1 detoxifies nitric oxide using NADH YP_001503499.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_001503500.1 PFAM: aminotransferase class I and II; KEGG: pcr:Pcryo_0738 aminotransferase, class I and II YP_001503501.1 PFAM: glycoside hydrolase family 18; Carbohydrate-binding family V/XII; SMART: chitinase II; KEGG: son:SO_4085 chitinase A YP_001503503.1 KEGG: vvy:VVA1355 hypothetical protein YP_001503504.1 KEGG: vvy:VVA1354 multidrug resistance efflux pump YP_001503505.1 KEGG: shn:Shewana3_0129 response regulator receiver protein YP_001503506.1 KEGG: slo:Shew_0491 hypothetical protein YP_001503507.1 KEGG: son:SO_1002 hypothetical protein YP_001503508.1 PFAM: Xanthine/uracil/vitamin C permease; KEGG: bha:BH0608 hypothetical protein YP_001503509.1 PFAM: CBS domain containing protein; transporter-associated region; Integral membrane protein TerC; KEGG: aha:AHA_2651 inner membrane protein YoaE YP_001503510.1 KEGG: pin:Ping_2564 PKD domain containing protein YP_001503511.1 KEGG: slo:Shew_0483 hypothetical protein YP_001503512.1 KEGG: slo:Shew_0482 hypothetical protein YP_001503513.1 PFAM: histidine kinase HAMP region domain protein; SMART: extracellular solute-binding protein family 3; metal-dependent phosphohydrolase HD region; KEGG: slo:Shew_3366 metal dependent phosphohydrolase YP_001503514.1 PFAM: protein of unknown function DUF1255; KEGG: maq:Maqu_2862 protein of unknown function DUF1255 YP_001503515.1 KEGG: slo:Shew_0481 hypothetical protein YP_001503516.1 KEGG: ecc:c5321 putative conserved protein YP_001503517.1 PFAM: pentapeptide repeat protein; KEGG: ppr:PBPRB0957 hypothetical protein YP_001503518.1 PFAM: chemotaxis sensory transducer; KEGG: vfi:VF1138 TcpI, toxin-coregulated pilus biosynthesis gene YP_001503520.1 PFAM: BCCT transporter; KEGG: vha:VIBHAR_06536 hypothetical protein YP_001503521.1 KEGG: slo:Shew_2884 glycine cleavage system regulatory protein-like protein YP_001503522.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: aha:AHA_0559 2',3'-cyclic-nucleotide 2'-phosphodiesterase YP_001503523.1 KEGG: ppd:Ppro_2456 hypothetical protein YP_001503524.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: she:Shewmr4_3373 cold-shock DNA-binding domain protein YP_001503527.1 PFAM: protein of unknown function DUF1568; KEGG: sdn:Sden_0135 protein of unknown function DUF1568 YP_001503528.1 PFAM: protein of unknown function DUF1568; KEGG: sdn:Sden_0135 protein of unknown function DUF1568 YP_001503530.1 KEGG: son:SO_0115 hypothetical protein YP_001503531.1 PFAM: NERD domain protein; KEGG: shn:Shewana3_0647 NERD domain protein YP_001503532.1 KEGG: vfi:VF2039 hypothetical protein YP_001503533.1 KEGG: vfi:VF2040 hypothetical protein YP_001503535.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001503536.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001503537.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: slo:Shew_0470 MATE efflux family protein YP_001503538.1 PFAM: pentapeptide repeat protein; KEGG: slo:Shew_0469 pentapeptide repeat protein YP_001503539.1 KEGG: slo:Shew_0465 hypothetical protein YP_001503540.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_0468 transcriptional regulator, LysR family YP_001503541.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_0467 efflux transporter, RND family, MFP subunit YP_001503542.1 PFAM: acriflavin resistance protein; KEGG: slo:Shew_0466 acriflavin resistance protein YP_001503543.1 KEGG: slo:Shew_0464 hypothetical protein YP_001503544.1 KEGG: slo:Shew_0463 hypothetical protein YP_001503545.1 KEGG: slo:Shew_0462 hypothetical protein YP_001503546.1 KEGG: slo:Shew_3539 hypothetical protein YP_001503547.1 KEGG: slo:Shew_0460 hypothetical protein YP_001503548.1 KEGG: slo:Shew_0459 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001503549.1 PFAM: PhoH family protein; SMART: AAA ATPase; Nucleotide binding protein PINc; KEGG: slo:Shew_0458 PhoH family protein YP_001503550.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_001503551.1 KEGG: slo:Shew_0456 hypothetical protein YP_001503552.1 KEGG: mmw:Mmwyl1_3491 transposase YP_001503553.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3340 integrase, catalytic region YP_001503554.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_0455 uncharacterized protein UPF0114 YP_001503555.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001503556.1 PFAM: response regulator receiver; KEGG: slo:Shew_0453 response regulator receiver protein YP_001503557.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: slo:Shew_0452 diguanylate cyclase YP_001503558.1 PFAM: protein of unknown function DUF1260; KEGG: sfr:Sfri_3513 protein of unknown function DUF1260 YP_001503559.1 KEGG: slo:Shew_0450 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase YP_001503560.1 PFAM: ABC-3 protein; KEGG: sbm:Shew185_3797 ABC-3 protein YP_001503561.1 PFAM: periplasmic solute binding protein; KEGG: shm:Shewmr7_3463 periplasmic solute binding protein YP_001503562.1 KEGG: slo:Shew_0447 hypothetical protein YP_001503563.1 KEGG: sbm:Shew185_3800 hypothetical protein YP_001503564.1 KEGG: slo:Shew_0445 hypothetical protein YP_001503565.1 PFAM: MscS Mechanosensitive ion channel; KEGG: slo:Shew_0444 MscS mechanosensitive ion channel YP_001503566.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_001503567.1 PFAM: MaoC domain protein dehydratase; KEGG: shn:Shewana3_0558 MaoC domain protein dehydratase YP_001503568.1 PFAM: GumN family protein; KEGG: slo:Shew_0438 GumN family protein YP_001503569.1 KEGG: slo:Shew_0437 hypothetical protein YP_001503570.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: shn:Shewana3_0554 diguanylate cyclase/phosphodiesterase YP_001503571.1 KEGG: sbm:Shew185_3811 hypothetical protein YP_001503572.1 KEGG: slo:Shew_0434 hypothetical protein YP_001503573.1 KEGG: slo:Shew_0433 hypothetical protein YP_001503574.1 KEGG: sbm:Shew185_3814 hypothetical protein YP_001503575.1 KEGG: slo:Shew_0431 hypothetical protein YP_001503576.1 PFAM: response regulator receiver; KEGG: shw:Sputw3181_0617 response regulator receiver protein YP_001503577.1 PFAM: histone family protein DNA-binding protein; KEGG: slo:Shew_0430 histone family protein DNA-binding protein YP_001503578.1 PFAM: conserved hypothetical protein; KEGG: she:Shewmr4_0547 hypothetical protein YP_001503579.1 KEGG: sbm:Shew185_3823 hypothetical protein YP_001503580.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: slo:Shew_0424 amino acid carrier protein YP_001503581.1 PFAM: major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_3494 major facilitator superfamily MFS_1 YP_001503582.1 KEGG: spc:Sputcn32_3815 glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001503583.1 TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter; KEGG: slo:Shew_0418 arsenical-resistance protein YP_001503584.1 PFAM: regulatory protein ArsR; KEGG: shm:Shewmr7_3499 transcriptional regulator, ArsR family YP_001503585.1 PFAM: PGAP1 family protein; KEGG: azo:azo0052 hypothetical secreted protein YP_001503586.1 PFAM: peptidase U62 modulator of DNA gyrase; KEGG: sbm:Shew185_0512 peptidase U62 modulator of DNA gyrase YP_001503587.1 PFAM: protein of unknown function DUF615; KEGG: slo:Shew_0415 protein of unknown function DUF615 YP_001503588.1 PFAM: Ig domain protein group 1 domain protein; KEGG: sbl:Sbal_3807 Ig domain protein, group 1 domain protein YP_001503589.1 PFAM: ABC-2 type transporter; KEGG: son:SO_4087 conserved hypothetical protein YP_001503590.1 PFAM: ABC-2 type transporter; KEGG: she:Shewmr4_3462 ABC-2 type transporter YP_001503591.1 PFAM: secretion protein HlyD family protein; KEGG: shn:Shewana3_3639 secretion protein HlyD family protein YP_001503592.1 PFAM: outer membrane efflux protein; KEGG: slo:Shew_0411 outer membrane efflux protein YP_001503593.1 PFAM: peptidase U62 modulator of DNA gyrase; KEGG: slo:Shew_0410 peptidase U62, modulator of DNA gyrase YP_001503594.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: spc:Sputcn32_0580 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001503595.1 KEGG: slo:Shew_0408 hypothetical protein YP_001503596.1 involved in the processing of the 5'end of 16S rRNA YP_001503597.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: slo:Shew_0406 maf protein YP_001503598.1 PFAM: Rod shape-determining protein MreD; KEGG: slo:Shew_0405 rod shape-determining protein MreD YP_001503599.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001503600.1 functions in MreBCD complex in some organisms YP_001503601.1 SMART: PA14-related domain protein; KEGG: slo:Shew_0402 MSHA biogenesis protein MshQ YP_001503602.1 KEGG: slo:Shew_0401 MSHA biogenesis protein MshP YP_001503603.1 KEGG: slo:Shew_0400 methylation site containing protein YP_001503604.1 KEGG: shw:Sputw3181_3602 methylation site containing protein YP_001503605.1 KEGG: spc:Sputcn32_0569 MSHA pilin protein MshC YP_001503606.1 KEGG: shm:Shewmr7_0473 methylation site containing protein YP_001503607.1 KEGG: son:SO_4105 MSHA pilin protein MshA YP_001503608.1 KEGG: shn:Shewana3_3657 methylation site containing protein YP_001503609.1 KEGG: shn:Shewana3_3658 hypothetical protein YP_001503610.1 PFAM: type II secretion system protein; KEGG: shw:Sputw3181_3608 type II secretion system protein YP_001503611.1 PFAM: type II secretion system protein E; General secretory system II protein E domain protein; KEGG: slo:Shew_0392 type II secretion system protein E YP_001503612.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: she:Shewmr4_3484 tetratricopeptide TPR_2 repeat protein YP_001503613.1 KEGG: sbm:Shew185_0485 MSHA biogenesis protein MshM YP_001503614.1 TIGRFAM: pilus (MSHA type) biogenesis protein MshL; PFAM: type II and III secretion system protein; Secretin domain protein; Secretin/TonB short domain; KEGG: slo:Shew_0389 pilus (MSHA type) biogenesis protein MshL YP_001503615.1 KEGG: shn:Shewana3_3664 MSHA biogenesis protein MshK YP_001503616.1 KEGG: slo:Shew_0387 MSHA biogenesis protein MshJ YP_001503617.1 PFAM: Fimbrial assembly family protein; KEGG: slo:Shew_0386 fimbrial assembly family protein YP_001503618.1 KEGG: sbm:Shew185_0480 conserved hypothetical biogenesis protein MshI YP_001503619.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_001503620.1 PFAM: malic protein domain protein; malic protein NAD-binding; KEGG: slo:Shew_0383 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) YP_001503621.1 PFAM: nuclease (SNase domain protein); KEGG: slo:Shew_0382 nuclease (SNase domain protein) YP_001503622.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001503623.1 KEGG: slo:Shew_0380 hypothetical protein YP_001503624.1 KEGG: slo:Shew_0379 primosomal protein N'; TIGRFAM: primosomal protein N'; PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases YP_001503625.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001503626.1 PFAM: Sporulation domain protein; KEGG: slo:Shew_0377 sporulation domain protein YP_001503627.1 heat shock protein involved in degradation of misfolded proteins YP_001503628.1 heat shock protein involved in degradation of misfolded proteins YP_001503629.1 PFAM: protein of unknown function DUF971; KEGG: slo:Shew_0373 protein of unknown function DUF971 YP_001503630.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_001503631.1 PFAM: major facilitator superfamily MFS_1; KEGG: shn:Shewana3_2502 major facilitator superfamily MFS_1 YP_001503632.1 PFAM: cyclic nucleotide-binding; KEGG: shn:Shewana3_2501 cyclic nucleotide-binding protein YP_001503633.1 KEGG: sbm:Shew185_0424 hypothetical protein YP_001503634.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: shn:Shewana3_3721 phosphoesterase, PA-phosphatase related YP_001503635.1 KEGG: slo:Shew_3369 hypothetical protein YP_001503636.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001503637.1 PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: slo:Shew_3372 arginase/agmatinase/formiminoglutamase YP_001503638.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: slo:Shew_3373 ubiquinone/menaquinone biosynthesis methyltransferase YP_001503639.1 PFAM: Sterol-binding domain protein; KEGG: slo:Shew_3374 protein of unknown function DUF1243 YP_001503640.1 TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: ABC-1 domain protein; KEGG: slo:Shew_3375 2-polyprenylphenol 6-hydroxylase YP_001503641.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: slo:Shew_3376 twin-arginine translocation protein, TatA/E family subunit YP_001503642.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: slo:Shew_3377 twin-arginine translocation protein, TatB subunit YP_001503643.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: slo:Shew_3378 sec-independent protein translocase, TatC subunit YP_001503644.1 KEGG: shm:Shewmr7_0399 hypothetical protein YP_001503645.1 PFAM: TatD-related deoxyribonuclease; KEGG: shm:Shewmr7_0398 TatD-related deoxyribonuclease YP_001503646.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Diverse 7TM receptor extracellular region 2; Diverse 7TM receptor transmembrane region; KEGG: slo:Shew_3381 diguanylate cyclase YP_001503647.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001503648.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001503649.1 PFAM: peptidase M23B; KEGG: slo:Shew_3446 peptidase M23B YP_001503650.1 KEGG: slo:Shew_3447 hypothetical protein YP_001503651.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001503652.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001503653.1 PFAM: cell division protein FtsA; KEGG: slo:Shew_3450 cell division protein FtsA YP_001503654.1 PFAM: cell division protein FtsQ; Polypeptide-transport-associated domain protein FtsQ-type; KEGG: slo:Shew_3451 polypeptide-transport-associated domain protein, FtsQ-type YP_001503655.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001503656.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001503657.1 TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: slo:Shew_3454 cell division protein FtsW YP_001503658.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001503659.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001503660.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: son:SO_4223 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanine ligase YP_001503661.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001503662.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: slo:Shew_3459 peptidoglycan glycosyltransferase YP_001503663.1 PFAM: cell division protein FtsL; KEGG: slo:Shew_3460 cell division protein FtsL YP_001503664.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: slo:Shew_3461 S-adenosyl-methyltransferase MraW YP_001503665.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001503666.1 KEGG: slo:Shew_3465 hypothetical protein YP_001503667.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase FGGY; KEGG: slo:Shew_3466 glycerol kinase YP_001503668.1 KEGG: slo:Shew_3467 hypothetical protein YP_001503669.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: son:SO_4232 long-chain fatty acid transport protein YP_001503670.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001503671.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001503672.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001503673.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001503674.1 KEGG: sbl:Sbal_0385 response regulator receiver protein YP_001503675.1 KEGG: shw:Sputw3181_0372 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases YP_001503676.1 PFAM: thioesterase superfamily protein; KEGG: son:SO_4242 hypothetical protein YP_001503677.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: sbl:Sbal_0382 RarD protein, DMT superfamily transporter YP_001503678.1 KEGG: shw:Sputw3181_0369 hypothetical protein YP_001503679.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_001503680.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001503681.1 required for 70S ribosome assembly YP_001503682.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001503683.1 KEGG: sfr:Sfri_3829 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein YP_001503684.1 catalyzes the formation of dUMP from dUTP YP_001503685.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_001503686.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; dienelactone hydrolase; KEGG: slo:Shew_3485 peptidase S9, prolyl oligopeptidase active site domain protein YP_001503687.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001503688.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001503689.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001503690.1 PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: slo:Shew_3489 YicC N-terminal domain protein YP_001503691.1 PFAM: HipA domain protein; KEGG: sdn:Sden_0307 HipA-like protein YP_001503692.1 PFAM: helix-turn-helix domain protein; KEGG: sbm:Shew185_0365 helix-turn-helix domain protein YP_001503693.1 PFAM: domain of unknown function DUF1732; KEGG: slo:Shew_3489 YicC N-terminal domain protein YP_001503694.1 KEGG: xcb:XC_3913 hypothetical protein YP_001503695.1 PFAM: purine or other phosphorylase family 1; KEGG: son:SO_3705 5-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase, putative YP_001503696.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: son:SO_3706 NupC family protein YP_001503697.1 KEGG: shn:Shewana3_1612 hypothetical protein YP_001503698.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: reu:Reut_B4119 regulatory protein GntR, HTH:GntR, C-terminal YP_001503699.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: bur:Bcep18194_C7696 transcriptional regulator, LysR family YP_001503700.1 PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; KEGG: cdf:CD3002 probable carbohydrate hydrolase YP_001503701.1 KEGG: reh:H16_A1259 D-galactarate dehydratase YP_001503702.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function YP_001503703.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: rca:Rcas_3855 mandelate racemase/muconate lactonizing protein YP_001503704.1 TIGRFAM: cytochrome C family protein; PFAM: multihaem cytochrome; KEGG: son:SO_1777 decaheme cytochrome c MtrA YP_001503705.1 KEGG: sfr:Sfri_3685 outer membrane protein YP_001503706.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: sfr:Sfri_3128 anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family protein YP_001503707.1 TIGRFAM: Dimethylsulfoxide reductase chain B; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: vpa:VP1448 anaerobic dimethyl sulfoxide reductase, subunit B YP_001503708.1 KEGG: son:SO_4356 hypothetical protein YP_001503709.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: sfr:Sfri_3126 cytoplasmic chaperone TorD family protein YP_001503711.1 PFAM: regulatory protein TetR; KEGG: slo:Shew_0277 transcriptional regulator, TetR family YP_001503712.1 TIGRFAM: oligopeptide transporters, OPT superfamily; PFAM: Oligopeptide transporter OPT superfamily protein; KEGG: pst:PSPTO_0148 oligopeptide transporter, OPT family YP_001503713.1 PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: sfr:Sfri_2899 OmpA/MotB domain protein YP_001503714.1 TIGRFAM: conserved repeat domain; putative outer membrane adhesin like proteiin; PFAM: protein of unknown function DUF11; KEGG: shn:Shewana3_0168 Ig family protein YP_001503715.1 KEGG: ppr:PBPRB1867 hypothetical protein YP_001503716.1 PFAM: Pyridoxal-dependent decarboxylase; KEGG: ppr:PBPRB0277 hypothetical amino acid decarboxylase YP_001503717.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: vha:VIBHAR_06184 hypothetical protein YP_001503718.1 PFAM: protein of unknown function DUF159; KEGG: maq:Maqu_3372 protein of unknown function DUF159 YP_001503719.1 PFAM: aminoglycoside phosphotransferase; KEGG: shn:Shewana3_3807 aminoglycoside phosphotransferase YP_001503720.1 KEGG: shn:Shewana3_3808 hypothetical protein YP_001503721.1 KEGG: slo:Shew_3496 hypothetical protein YP_001503722.1 Essential for recycling GMP and indirectly, cGMP YP_001503723.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001503724.1 KEGG: slo:Shew_3499 (p)ppGpp synthetase I, SpoT/RelA; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; metal-dependent phosphohydrolase HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase HD region YP_001503725.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: slo:Shew_3500 putative endoribonuclease L-PSP YP_001503726.1 specifically modifies tRNA at position G18 YP_001503727.1 PFAM: AMP-dependent synthetase and ligase; KEGG: slo:Shew_3502 AMP-dependent synthetase and ligase YP_001503728.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: shw:Sputw3181_3775 Na+/Ca+ antiporter, CaCA family YP_001503729.1 catalyzes branch migration in Holliday junction intermediates YP_001503730.1 KEGG: slo:Shew_3508 hypothetical protein YP_001503731.1 KEGG: shm:Shewmr7_3674 hypothetical protein YP_001503732.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: slo:Shew_3510 phospholipid/glycerol acyltransferase YP_001503733.1 KEGG: slo:Shew_3511 acyl carrier protein, putative YP_001503734.1 carries the fatty acid chain in fatty acid biosynthesis YP_001503735.1 KEGG: slo:Shew_3513 hypothetical protein YP_001503736.1 KEGG: slo:Shew_3514 hypothetical protein YP_001503737.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: sbm:Shew185_0336 thioester dehydrase family protein YP_001503738.1 PFAM: glycosyl transferase family 2; lipid A biosynthesis acyltransferase; KEGG: slo:Shew_3516 glycosyl transferase, family 2 YP_001503739.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: slo:Shew_3517 histidine ammonia-lyase YP_001503740.1 KEGG: shn:Shewana3_0334 conserved hypothetical 4-hydroxybenzoyl-CoA thioesterase YP_001503741.1 KEGG: slo:Shew_3519 outer membrane lipoprotein carrier protein LolA YP_001503742.1 KEGG: spc:Sputcn32_0437 hypothetical protein YP_001503743.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; tryptophan halogenase; KEGG: shm:Shewmr7_3686 monooxygenase, FAD-binding protein YP_001503744.1 KEGG: son:SO_4379 hypothetical protein YP_001503745.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001503746.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: sfr:Sfri_0339 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ YP_001503747.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001503748.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001503749.1 PFAM: Rhodanese domain protein; KEGG: she:Shewmr4_0323 rhodanese domain protein YP_001503750.1 TIGRFAM: thioesterase domain, putative; PFAM: Thioesterase putative; KEGG: she:Shewmr4_0320 thioesterase domain, putative YP_001503751.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001503752.1 KEGG: sbm:Shew185_0316 hypothetical protein YP_001503753.1 PFAM: alpha/beta hydrolase fold; KEGG: slo:Shew_3544 alpha/beta hydrolase fold YP_001503754.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_001503755.1 KEGG: slo:Shew_3546 hypothetical protein YP_001503756.1 KEGG: sbm:Shew185_0312 hypothetical protein YP_001503757.1 KEGG: slo:Shew_3549 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001503758.1 TIGRFAM: pyridoxal kinase; KEGG: vfi:VF2056 pyridoxine kinase YP_001503759.1 PFAM: Disulphide bond formation protein DsbB; KEGG: shm:Shewmr7_0287 disulphide bond formation protein DsbB YP_001503760.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: saz:Sama_3415 virulence regulator BipA YP_001503761.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_001503762.1 PFAM: sodium:dicarboxylate symporter; KEGG: shn:Shewana3_0297 sodium:dicarboxylate symporter YP_001503763.1 KEGG: pha:PSHAa1478 hypothetical protein YP_001503764.1 PFAM: helix-turn-helix domain protein; KEGG: pat:Patl_1386 transcriptional regulator, XRE family YP_001503765.1 KEGG: sus:Acid_2127 glycosyl hydrolase, BNR repeat-containing protein YP_001503767.1 PFAM: aminotransferase class V; KEGG: sbm:Shew185_0300 aminotransferase class V YP_001503768.1 PFAM: Domain of unknown function DUF1864; KEGG: sbm:Shew185_0299 domain of unknown function DUF1864 YP_001503769.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: slo:Shew_3558 transcriptional regulator, AsnC family YP_001503770.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: shw:Sputw3181_0227 iron-containing alcohol dehydrogenase YP_001503771.1 PFAM: ThiJ/PfpI domain protein; KEGG: sbm:Shew185_0262 ThiJ/PfpI domain protein YP_001503772.1 KEGG: ppr:PBPRA1243 hypothetical protein YP_001503773.1 KEGG: slo:Shew_3559 hypothetical protein YP_001503774.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sbl:Sbal_0267 signal transduction histidine kinase, nitrogen specific, NtrB YP_001503775.1 KEGG: shm:Shewmr7_3764 nitrogen metabolism transcriptional regulator, NtrC, fis family; TIGRFAM: nitrogen regulation protein NR(I); PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001503776.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: shm:Shewmr7_3767 cation diffusion facilitator family transporter YP_001503777.1 PFAM: protein of unknown function Spy-related; KEGG: she:Shewmr4_0253 protein of unknown function, Spy-related YP_001503778.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: slo:Shew_3570 two component transcriptional regulator, winged helix family YP_001503779.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: slo:Shew_3571 integral membrane sensor signal transduction histidine kinase YP_001503780.1 PFAM: regulatory protein TetR; KEGG: sbl:Sbal_0259 putative transcriptional regulator, TetR family YP_001503781.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: shm:Shewmr7_2226 transcriptional regulator, LysR family YP_001503782.1 KEGG: sbl:Sbal_0256 hypothetical protein YP_001503783.1 KEGG: shm:Shewmr7_2229 tetraheme cytochrome c YP_001503784.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: spc:Sputcn32_3536 flavocytochrome c YP_001503785.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: vfi:VF0021 transcriptional regulators, LysR family YP_001503786.1 TIGRFAM: Quinone oxidoreductase putative YhdH/YhfP; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sbl:Sbal_0250 alcohol dehydrogenase, zinc-binding domain protein YP_001503787.1 PFAM: aldehyde dehydrogenase; KEGG: shm:Shewmr7_3772 aldehyde dehydrogenase (NAD(+)) YP_001503788.1 KEGG: son:SO_2407 hypothetical protein YP_001503789.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Radical SAM domain protein; KEGG: sbm:Shew185_2284 radical SAM domain protein YP_001503790.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbm:Shew185_2285 transcriptional regulator, LysR family YP_001503791.1 TIGRFAM: RNA methyltransferase, TrmH family, group 2; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: sbm:Shew185_4126 RNA methyltransferase, TrmH family, group 2 YP_001503792.1 PFAM: peptidase M16 domain protein; KEGG: shn:Shewana3_3939 DNA-directed RNA polymerase YP_001503793.1 PFAM: peptidase M16 domain protein; KEGG: slo:Shew_3581 peptidase M16 domain protein YP_001503794.1 PFAM: type IV pilus assembly PilZ; KEGG: slo:Shew_3582 hypothetical protein YP_001503795.1 KEGG: bfs:BF1302 hypothetical protein YP_001503796.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: slo:Shew_3583 methyltransferase type 12 YP_001503797.1 KEGG: slo:Shew_3584 hypothetical protein YP_001503798.1 KEGG: shw:Sputw3181_3881 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001503799.1 PFAM: DTW domain containing protein; KEGG: sbm:Shew185_4137 DTW domain containing protein YP_001503800.1 KEGG: slo:Shew_3587 hypothetical protein YP_001503801.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: shn:Shewana3_3948 drug resistance transporter, Bcr/CflA subfamily YP_001503802.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbl:Sbal_0195 transcriptional regulator, LysR family YP_001503803.1 KEGG: slo:Shew_3590 hypothetical protein YP_001503804.1 KEGG: slo:Shew_3591 hypothetical protein YP_001503805.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: slo:Shew_3592 Sel1 domain protein repeat-containing protein YP_001503806.1 KEGG: slo:Shew_3593 hypothetical protein YP_001503807.1 KEGG: slo:Shew_3594 hypothetical protein YP_001503808.1 PFAM: protein of unknown function DUF1332; KEGG: slo:Shew_3595 protein of unknown function DUF1332 YP_001503809.1 KEGG: shw:Sputw3181_2184 hypothetical protein YP_001503810.1 PFAM: Polysulphide reductase NrfD; KEGG: shw:Sputw3181_3893 polysulphide reductase, NrfD YP_001503811.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: shw:Sputw3181_3894 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001503812.1 KEGG: shw:Sputw3181_3895 formate-dependent nitrite reductase YP_001503813.1 KEGG: slo:Shew_3155 hypothetical protein YP_001503814.1 PFAM: regulatory protein LysR; KEGG: shn:Shewana3_3964 transcriptional regulator, LysR family YP_001503815.1 PFAM: regulatory protein LysR; KEGG: slo:Shew_3153 transcriptional regulator, LysR family YP_001503816.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_001503817.1 PFAM: alpha/beta hydrolase fold; KEGG: she:Shewmr4_3768 alpha/beta hydrolase fold YP_001503818.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_001503819.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: shm:Shewmr7_3843 O-succinylbenzoate-CoA ligase YP_001503821.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: sdn:Sden_3445 transposase IS116/IS110/IS902 YP_001503822.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001503823.1 PFAM: protein of unknown function DUF214; KEGG: slo:Shew_3604 protein of unknown function DUF214 YP_001503824.1 KEGG: sbm:Shew185_4163 cell division ATP-binding protein FtsE; TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: AAA ATPase YP_001503825.1 KEGG: sbm:Shew185_4164 signal recognition particle-docking protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase YP_001503826.1 TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein; KEGG: sfr:Sfri_0274 putative methyltransferase YP_001503827.1 PFAM: protein of unknown function DUF1145; KEGG: spc:Sputcn32_0287 protein of unknown function DUF1145 YP_001503828.1 PFAM: NapC/NirT cytochrome c domain protein; KEGG: slo:Shew_3540 NapC/NirT cytochrome c domain protein YP_001503829.1 KEGG: slo:Shew_3539 hypothetical protein YP_001503830.1 KEGG: sfr:Sfri_0591 hypothetical protein YP_001503831.1 KEGG: slo:Shew_3537 hypothetical protein YP_001503832.1 KEGG: slo:Shew_3536 hypothetical protein YP_001503833.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: sfr:Sfri_0267 efflux transporter, RND family, MFP subunit YP_001503834.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: sfr:Sfri_0266 heavy metal efflux pump, CzcA family protein YP_001503835.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: slo:Shew_3533 glyoxalase/bleomycin resistance protein/dioxygenase YP_001503836.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sdn:Sden_0245 GGDEF domain YP_001503837.1 PFAM: secretion protein HlyD family protein; KEGG: ppr:PBPRB1680 putative multidrug resistance efflux pump YP_001503838.1 KEGG: ppr:PBPRB1681 putative permease of the major facilitator superfamily YP_001503839.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ppr:PBPRB1682 hypothetical AraC-type transcriptional regulator YP_001503840.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: slo:Shew_3531 aromatic amino acid transporter YP_001503841.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_001503842.1 Represses a number of genes involved in the response to DNA damage YP_001503843.1 KEGG: sbm:Shew185_4179 hypothetical protein YP_001503844.1 KEGG: slo:Shew_0125 cytochrome c oxidase, subunit II; TIGRFAM: Cytochrome c oxidase subunit II; PFAM: cytochrome c oxidase subunit II; cytochrome c class I; cytochrome C oxidase subunit II transmembrane region YP_001503845.1 KEGG: shn:Shewana3_3992 cytochrome c oxidase, subunit I; TIGRFAM: Cytochrome c oxidase subunit I type; PFAM: cytochrome c oxidase subunit I YP_001503846.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_001503847.1 PFAM: cytochrome c oxidase subunit III; KEGG: slo:Shew_0122 cytochrome c oxidase, subunit III YP_001503848.1 KEGG: shw:Sputw3181_0129 hypothetical protein YP_001503849.1 KEGG: slo:Shew_0119 hypothetical protein YP_001503850.1 PFAM: cytochrome oxidase assembly; KEGG: sdn:Sden_3523 cytochrome oxidase assembly YP_001503851.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001503852.1 PFAM: electron transport protein SCO1/SenC; KEGG: slo:Shew_0116 electron transport protein SCO1/SenC YP_001503853.1 PFAM: polysaccharide deacetylase; KEGG: sbl:Sbal_0145 polysaccharide deacetylase YP_001503854.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: sbl:Sbal_0144 MATE efflux family protein YP_001503855.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_001503856.1 PFAM: peptidase M14 carboxypeptidase A; KEGG: slo:Shew_0105 peptidase M14, carboxypeptidase A YP_001503857.1 KEGG: shw:Sputw3181_0113 competence protein ComF YP_001503858.1 KEGG: sbm:Shew185_4199 BioH protein; TIGRFAM: bioH protein; PFAM: alpha/beta hydrolase fold YP_001503859.1 KEGG: saz:Sama_3506 hypothetical protein YP_001503860.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; KEGG: slo:Shew_3634 RNA binding S1 domain protein YP_001503861.1 TIGRFAM: transcription elongation factor GreB; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: stm:STM3503 transcription elongation factor and transcript cleavage YP_001503862.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_001503863.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_001503864.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_3904 methyl-accepting chemotaxis sensory transducer YP_001503865.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: son:SO_3874 transcriptional regulator, LysR family YP_001503866.1 KEGG: son:SO_3873 hypothetical protein YP_001503867.1 PFAM: Arylsulfotransferase; KEGG: son:SO_3872 arylsulfate sulfotransferase YP_001503868.1 PFAM: DSBA oxidoreductase; KEGG: son:SO_3871 thiol:disulfide interchange protein, DsbA family YP_001503869.1 PFAM: Disulphide bond formation protein DsbB; KEGG: son:SO_3870 disulfide bond formation protein YP_001503870.1 PFAM: regulatory protein TetR; KEGG: slo:Shew_0277 transcriptional regulator, TetR family YP_001503871.1 KEGG: vfi:VF0719 putative sugar hydrolase YP_001503872.1 PFAM: Arylsulfotransferase; KEGG: spt:SPA3941 hypothetical protein YP_001503873.1 PFAM: DSBA oxidoreductase; KEGG: son:SO_3871 thiol:disulfide interchange protein, DsbA family YP_001503874.1 PFAM: Disulphide bond formation protein DsbB; KEGG: son:SO_3870 disulfide bond formation protein YP_001503875.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: slo:Shew_2670 transcriptional regulator, LysR family YP_001503876.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: slo:Shew_2671 alpha/beta hydrolase fold-3 domain protein YP_001503877.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities YP_001503878.1 PFAM: MaoC domain protein dehydratase; KEGG: drm:Dred_0577 MaoC domain protein dehydratase YP_001503879.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA YP_001503880.1 PFAM: AMP-dependent synthetase and ligase; KEGG: slo:Shew_2673 AMP-dependent synthetase and ligase YP_001503881.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine YP_001503882.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA YP_001503883.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism YP_001503884.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase YP_001503885.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit ; Electron transfer flavoprotein alpha subunit; KEGG: slo:Shew_2678 electron transfer flavoprotein, alpha subunit YP_001503886.1 PFAM: monooxygenase FAD-binding; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: slo:Shew_2679 FAD dependent oxidoreductase YP_001503887.1 KEGG: slo:Shew_2680 putative ferredoxin YP_001503888.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: slo:Shew_2681 general substrate transporter YP_001503889.1 KEGG: slo:Shew_2682 hypothetical protein YP_001503890.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: sdn:Sden_2551 magnesium transporter YP_001503892.1 PFAM: protein of unknown function DUF548; KEGG: sfr:Sfri_3857 protein of unknown function DUF548 YP_001503893.1 KEGG: slo:Shew_2521 decaheme cytochrome c MtrF YP_001503894.1 PFAM: transcriptional regulator domain protein; KEGG: sbm:Shew185_3867 transcriptional regulator, CadC YP_001503895.1 PFAM: protein of unknown function DUF519; KEGG: spc:Sputcn32_0098 protein of unknown function DUF519 YP_001503896.1 KEGG: son:SO_4342 hypothetical protein YP_001503897.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ppr:PBPRB1939 hypothetical transcriptional regulator YP_001503898.1 sodium/drug antiporter; functions as a Na(+)-driven Na(+)/drug antiporter; member of multidrug and toxic compound extrusion (MATE) family; extrudes acriflavines and other compounds by utilizing the sodium gradient YP_001503899.1 PFAM: Lytic transglycosylase catalytic; KEGG: shm:Shewmr7_3923 lytic transglycosylase, catalytic YP_001503900.1 KEGG: slo:Shew_3651 hypothetical protein YP_001503901.1 PFAM: LemA family protein; KEGG: slo:Shew_3652 LemA family protein YP_001503902.1 PFAM: AbgT putative transporter; short chain fatty acid transporter; KEGG: slo:Shew_3654 AbgT putative transporter YP_001503903.1 PFAM: AbgT putative transporter; KEGG: saz:Sama_3559 putative efflux pump component MtrF YP_001503904.1 TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: kpn:KPN_02690 phosphodiesterase YP_001503905.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: slo:Shew_0032 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family YP_001503906.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: slo:Shew_0031 efflux transporter, RND family, MFP subunit YP_001503907.1 KEGG: sbl:Sbal_0127 conserved hypothetical 3-methyladenine DNA glycosylase YP_001503908.1 PFAM: Glutathione S-transferase domain; KEGG: son:SO_4697 glutathione S-transferase YP_001503909.1 KEGG: shm:Shewmr7_3934 hypothetical protein YP_001503910.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: slo:Shew_3657 oligopeptidase A YP_001503911.1 KEGG: slo:Shew_3658 hypothetical protein YP_001503912.1 KEGG: sbm:Shew185_4258 hypothetical protein YP_001503913.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001503914.1 KEGG: sfr:Sfri_3563 transposase YP_001503915.1 PFAM: Integrase catalytic region; KEGG: sfr:Sfri_3562 integrase, catalytic region YP_001503916.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: vfi:VF1121 BCCT family transporter YP_001503917.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: ppr:PBPRB1413 putative NADH-dependent flavin oxidoreductase YP_001503918.1 KEGG: shw:Sputw3181_0952 hypothetical protein YP_001503919.1 KEGG: pin:Ping_2027 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20 YP_001503920.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: rci:RCIX1169 hypothetical protein YP_001503921.1 PFAM: Asp/Glu racemase; KEGG: pin:Ping_2031 Asp/Glu racemase YP_001503922.1 PFAM: creatinase; peptidase M24; KEGG: pin:Ping_2026 peptidase M24 YP_001503923.1 PFAM: YheO domain protein; KEGG: sfr:Sfri_0689 YheO domain protein YP_001503924.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: vha:VIBHAR_02784 hypothetical protein YP_001503925.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_001503926.1 PFAM: conserved hypothetical protein; KEGG: sbm:Shew185_4296 conserved hypothetical protein 698 YP_001503927.1 PFAM: ThiJ/PfpI domain protein; KEGG: slo:Shew_3669 ThiJ/PfpI domain protein YP_001503928.1 PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: son:SO_4711 HD domain protein YP_001503929.1 KEGG: slo:Shew_3672 hypothetical protein YP_001503930.1 KEGG: sbm:Shew185_4307 hypothetical protein YP_001503931.1 PFAM: cobalt transport protein; KEGG: sbl:Sbal_0091 cobalt transport protein YP_001503932.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_3959 ABC transporter related YP_001503933.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sbl:Sbal_0089 TonB-dependent receptor, plug YP_001503934.1 TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: slo:Shew_3677 isochorismate synthase YP_001503935.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: shw:Sputw3181_0078 hypothetical protein YP_001503936.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shn:Shewana3_4074 acetyltransferase, GNAT family YP_001503937.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: slo:Shew_3681 integral membrane sensor signal transduction histidine kinase YP_001503938.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: slo:Shew_3682 two component, sigma54 specific, transcriptional regulator, fis family YP_001503939.1 KEGG: slo:Shew_3683 extracellular solute-binding protein, family 1 YP_001503940.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: slo:Shew_3684 binding-protein-dependent transport systems inner membrane component YP_001503941.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_3685 ABC transporter-related protein YP_001503942.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein A; KEGG: slo:Shew_3686 molybdopterin-guanine dinucleotide biosynthesis protein A YP_001503943.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin binding domain; molybdopterin-guanine dinucleotide biosynthesis MobB region; MoeA domain protein domain I and II; MoeA domain protein domain IV; KEGG: slo:Shew_3687 molybdopterin-guanine dinucleotide biosynthesis protein B YP_001503944.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001503945.1 KEGG: vvu:VV2_1156 membrane-fusion protein YP_001503946.1 SMART: Ig domain protein group 1 domain protein; KEGG: sdn:Sden_2330 Ig-like, group 1 YP_001503948.1 KEGG: shw:Sputw3181_0068 hypothetical protein YP_001503949.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001503950.1 PFAM: SNARE associated Golgi protein; KEGG: shm:Shewmr7_3976 hypothetical protein YP_001503951.1 KEGG: sfr:Sfri_3925 hypothetical protein YP_001503952.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001503953.1 TIGRFAM: pseudouridine synthase Rlu family protein, TIGR01621; PFAM: pseudouridine synthase; KEGG: sbl:Sbal_0295 pseudouridine synthase Rlu family protein, TIGR01621 YP_001503954.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: slo:Shew_0098 integral membrane sensor signal transduction histidine kinase YP_001503955.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: slo:Shew_0097 two component transcriptional regulator, winged helix family YP_001503956.1 KEGG: shw:Sputw3181_0250 hypothetical protein YP_001503957.1 PFAM: conserved hypothetical protein; KEGG: slo:Shew_0095 conserved hypothetical protein 156 YP_001503958.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_0094 ABC transporter-related protein YP_001503959.1 TIGRFAM: molybdate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sbm:Shew185_0282 molybdate ABC transporter, inner membrane subunit YP_001503960.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: slo:Shew_0092 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_001503961.1 PFAM: molybdopterin biosynthesis MoaE protein; KEGG: she:Shewmr4_0276 molybdopterin biosynthesis MoaE YP_001503962.1 TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: shn:Shewana3_0276 molybdopterin converting factor, subunit 1 YP_001503963.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001503964.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdenum cofactor biosynthesis protein B; PFAM: molybdopterin binding domain; KEGG: slo:Shew_0088 molybdenum cofactor biosynthesis protein B YP_001503965.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001503966.1 PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase; KEGG: slo:Shew_0086 electron-transferring-flavoprotein dehydrogenase YP_001503967.1 KEGG: slo:Shew_0084 hypothetical protein YP_001503968.1 PFAM: 3-alpha domain protein; MOSC domain containing protein; KEGG: shw:Sputw3181_0239 MOSC domain containing protein YP_001503969.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sbl:Sbal_0279 diguanylate cyclase YP_001503970.1 PFAM: PfkB domain protein; KEGG: she:Shewmr4_0267 PfkB domain protein YP_001503971.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001503972.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: sbm:Shew185_4112 formate dehydrogenase, gamma subunit YP_001503973.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: saz:Sama_3608 formate dehydrogenase, iron-sulfur subunit YP_001503974.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: saz:Sama_3609 formate dehydrogenase, alpha subunit YP_001503975.1 TIGRFAM: Formate dehydrogenase region TAT target; KEGG: slo:Shew_0062 hypothetical protein YP_001503976.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: sbm:Shew185_4112 formate dehydrogenase, gamma subunit YP_001503977.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: saz:Sama_3608 formate dehydrogenase, iron-sulfur subunit YP_001503978.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: slo:Shew_0063 molybdopterin oxidoreductase YP_001503979.1 TIGRFAM: Formate dehydrogenase region TAT target; KEGG: slo:Shew_0062 hypothetical protein YP_001503980.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: slo:Shew_0061 formate dehydrogenase, gamma subunit YP_001503981.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: shw:Sputw3181_3872 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001503982.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: slo:Shew_0059 molybdopterin oxidoreductase YP_001503983.1 TIGRFAM: Formate dehydrogenase region TAT target; KEGG: slo:Shew_0058 twin-arginine translocation pathway signal YP_001503984.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: slo:Shew_0057 cytoplasmic chaperone TorD family protein YP_001503985.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: slo:Shew_0056 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001503986.1 KEGG: spc:Sputcn32_0341 hypothetical protein YP_001503987.1 KEGG: slo:Shew_0054 hypothetical protein YP_001503988.1 PFAM: formate dehydrogenase subunit FdhD; KEGG: slo:Shew_0053 formate dehydrogenase, subunit FdhD YP_001503989.1 KEGG: slo:Shew_0052 DNA binding domain, excisionase family YP_001503990.1 KEGG: sdn:Sden_1152 hypothetical protein YP_001503991.1 PFAM: protein of unknown function DUF890; KEGG: slo:Shew_3741 protein of unknown function DUF890 YP_001503992.1 PFAM: flagellar basal body-associated protein FliL; KEGG: sfr:Sfri_0049 flagellar basal body-associated protein FliL YP_001503993.1 PFAM: Chorismate lyase; KEGG: sbl:Sbal_4229 chorismate lyase YP_001503994.1 PFAM: PKD domain containing protein; peptidase M6 immune inhibitor A; KEGG: slo:Shew_3744 peptidase M6, immune inhibitor A YP_001503995.1 KEGG: sdn:Sden_0093 hypothetical protein YP_001503996.1 PFAM: glycoside hydrolase family 37; KEGG: slo:Shew_3745 glycoside hydrolase, family 37 YP_001503997.1 PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: slo:Shew_3746 multiple antibiotic resistance (MarC)-related protein YP_001503998.1 KEGG: slo:Shew_3747 hypothetical protein YP_001503999.1 PFAM: protein of unknown function DUF833; KEGG: slo:Shew_3748 protein of unknown function DUF833 YP_001504000.1 KEGG: slo:Shew_3749 hypothetical protein YP_001504001.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: slo:Shew_3750 phospholipid/glycerol acyltransferase YP_001504002.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: slo:Shew_3751 lysine exporter protein (LysE/YggA) YP_001504003.1 PFAM: MscS Mechanosensitive ion channel; KEGG: shm:Shewmr7_0112 MscS mechanosensitive ion channel YP_001504004.1 KEGG: slo:Shew_3753 hypothetical protein YP_001504005.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: son:SO_A0164 iron-containing alcohol dehydrogenase YP_001504006.1 KEGG: vfi:VF1351 hypothetical protein YP_001504007.1 KEGG: slo:Shew_3754 hypothetical protein YP_001504008.1 PFAM: protein of unknown function DUF81; KEGG: bce:BC1620 hypothetical membrane protein YP_001504009.1 KEGG: bbr:BB4545 D-cysteine desulfhydrase YP_001504010.1 PFAM: Na+/H+ antiporter NhaC; KEGG: dde:Dde_2580 Na+/H+ antiporter family protein YP_001504011.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: vha:VIBHAR_03649 hypothetical protein YP_001504012.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sal:Sala_2416 transcriptional regulator, LysR family YP_001504013.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_001504014.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001504015.1 TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: slo:Shew_3758 transcriptional regulator, histidine utilization repressor, GntR family YP_001504016.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_001504017.1 KEGG: vpa:VPA0799 hypothetical protein YP_001504018.1 SMART: AAA ATPase; KEGG: vpa:VPA0800 hypothetical protein YP_001504019.1 PFAM: protein of unknown function DUF214; KEGG: sus:Acid_5729 protein of unknown function DUF214 YP_001504020.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sde:Sde_0308 ABC transporter ATP-binding protein YP_001504021.1 KEGG: cps:CPS_2118 efflux transporter, RND family, MFP subunit YP_001504023.1 PFAM: Lytic transglycosylase catalytic; KEGG: ilo:IL0198 membrane-bound lytic murein transglycosylase C YP_001504024.1 KEGG: sfr:Sfri_3965 hypothetical protein YP_001504025.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_0085 2,3-diketo-5-methylthio-1-phosphopentane phosphatase YP_001504026.1 KEGG: shw:Sputw3181_4009 hypothetical protein YP_001504027.1 KEGG: ppr:PBPRB0920 hypothetical protein YP_001504028.1 PFAM: thioesterase superfamily protein; KEGG: sdn:Sden_0074 thioesterase superfamily YP_001504029.1 KEGG: son:SO_0079 hypothetical protein YP_001504030.1 PFAM: thioesterase superfamily protein; KEGG: sfr:Sfri_3970 thioesterase superfamily protein YP_001504031.1 PFAM: AMP-dependent synthetase and ligase; KEGG: she:Shewmr4_0078 AMP-dependent synthetase and ligase YP_001504032.1 KEGG: slo:Shew_3777 hypothetical protein YP_001504033.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sdn:Sden_0070 ABC transporter related YP_001504034.1 PFAM: regulatory protein GntR HTH; KEGG: slo:Shew_3779 transcriptional regulator, GntR family YP_001504035.1 PFAM: alpha/beta hydrolase fold; TAP domain protein; KEGG: slo:Shew_3780 TAP domain protein YP_001504036.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: slo:Shew_3781 ABC transporter-related protein YP_001504037.1 KEGG: slo:Shew_3782 ABC-2 type transporter YP_001504038.1 KEGG: shw:Sputw3181_4024 hypothetical protein YP_001504039.1 PFAM: helix-turn-helix- domain containing protein AraC type; ThiJ/PfpI domain protein; KEGG: slo:Shew_3785 transcriptional regulator, AraC family YP_001504040.1 KEGG: slo:Shew_3786 hypothetical protein YP_001504041.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: ilo:IL2343 methyl-accepting chemotaxis protein (contains HAMP domain) YP_001504042.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_001504043.1 KEGG: bth:BT_1162 hypothetical protein YP_001504044.1 KEGG: vpa:VP1357 hypothetical protein YP_001504045.1 PFAM: NLP/P60 protein; KEGG: sbm:Shew185_0058 NLP/P60 protein YP_001504046.1 PFAM: ABC-2 type transporter; KEGG: cps:CPS_1248 ABC transporter, permease protein YP_001504047.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cps:CPS_1249 ABC transporter, ATP-binding protein YP_001504048.1 KEGG: cps:CPS_1250 conserved hypothetical protein YP_001504049.1 KEGG: vvy:VVA0335 outer membrane protein YP_001504050.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: vvy:VVA0334 agglutination protein YP_001504051.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: vvu:VV2_1516 secretion protein, HlyD family YP_001504052.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: vvy:VVA0332 putative RTX toxin secretion ATP-binding protein YP_001504053.1 KEGG: vvu:VV2_1514 autotransporter adhesin YP_001504054.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: vpa:VPA0216 putative transcription regulator protein YP_001504055.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sfr:Sfri_1566 glyoxalase/bleomycin resistance protein/dioxygenase YP_001504056.1 KEGG: cps:CPS_3499 hypothetical protein YP_001504057.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: slo:Shew_3802 HI0933 family protein YP_001504058.1 PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: sdn:Sden_3445 transposase IS116/IS110/IS902 YP_001504059.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001504060.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001504061.1 PFAM: Rhodanese domain protein; KEGG: slo:Shew_3805 rhodanese domain protein YP_001504062.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001504063.1 PFAM: peptidase M23B; KEGG: slo:Shew_3807 peptidase M23B YP_001504064.1 KEGG: slo:Shew_3808 carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: peptidase S41; SMART: PDZ/DHR/GLGF domain protein YP_001504065.1 PFAM: protein of unknown function DUF610 YibQ; KEGG: slo:Shew_3809 protein of unknown function DUF610, YibQ YP_001504066.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: shn:Shewana3_0047 transcriptional regulator, BadM/Rrf2 family YP_001504067.1 PFAM: protein of unknown function UPF0153; KEGG: slo:Shew_3811 protein of unknown function UPF0153 YP_001504068.1 TIGRFAM: Cytochrome c oxidase cbb3 type accessory protein FixG; KEGG: slo:Shew_3812 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001504069.1 KEGG: sbm:Shew185_4357 hypothetical protein YP_001504070.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_001504071.1 KEGG: saz:Sama_3636 hypothetical protein YP_001504072.1 PFAM: sodium/hydrogen exchanger; KEGG: slo:Shew_3170 sodium/hydrogen exchanger YP_001504073.1 TIGRFAM: phosphate binding protein; KEGG: son:SO_4292 phosphate ABC transporter, periplasmic phosphate-binding protein YP_001504074.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO_4291 phosphate ABC transporter, permease protein YP_001504075.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO_4290 phosphate ABC transporter, permease protein YP_001504076.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001504077.1 KEGG: cps:CPS_2434 hypothetical protein YP_001504078.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_001504079.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001504080.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: she:Shewmr4_3921 transcriptional regulator, DeoR family YP_001504081.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: slo:Shew_3841 TonB-dependent siderophore receptor YP_001504082.1 TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; KEGG: slo:Shew_3842 UDP-N-acetylglucosamine pyrophosphorylase YP_001504083.1 PFAM: DsrE family protein; KEGG: slo:Shew_3843 DsrE family protein YP_001504084.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001504085.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001504086.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001504087.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001504088.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001504089.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001504090.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001504091.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001504092.1 PFAM: ATP synthase I chain; KEGG: slo:Shew_3852 ATP synthase I chain YP_001504093.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: saz:Sama_3652 ParB family protein YP_001504094.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: slo:Shew_3854 cobyrinic acid a,c-diamide synthase YP_001504095.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001504096.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001504097.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001504098.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: ppr:PBPRB1417 hypothetical inosine-uridine preferring nucleoside hydrolase YP_001504099.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sfr:Sfri_3118 lysine exporter protein (LysE/YggA) YP_001504100.1 KEGG: slo:Shew_0364 MshA, mannose-sensitive haemaglutinin YP_001504101.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001504102.1 PFAM: 60 kDa inner membrane insertion protein; KEGG: slo:Shew_3866 60 kDa inner membrane insertion protein YP_001504103.1 PFAM: protein of unknown function DUF37; KEGG: shw:Sputw3181_4093 protein of unknown function DUF37 YP_001504104.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001504105.1 in Escherichia coli transcription of this gene is enhanced by polyamines