-- dump date 20140620_064450 -- class Genbank::CDS -- table cds_note -- id note YP_001181536.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001181537.1 KEGG: shm:Shewmr7_0002 DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain YP_001181538.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001181539.1 KEGG: son:SO0011 DNA gyrase subunit B; TIGRFAM: DNA gyrase, B subunit; PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein domain protein; TOPRIM domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein; SMART: DNA topoisomerase II YP_001181540.1 PFAM: HDOD; KEGG: shm:Shewmr7_0007 putative signal transduction protein YP_001181541.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001181542.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001181543.1 KEGG: shm:Shewmr7_0010 DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase YP_001181544.1 PFAM: peptidase S9B, dipeptidylpeptidase IV domain protein; amidohydrolase; WD40 domain protein beta Propeller; KEGG: she:Shewmr4_0011 amidohydrolase YP_001181545.1 KEGG: she:Shewmr4_0012 hypothetical protein YP_001181546.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_001181547.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001181548.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001181549.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_001181550.1 PFAM: protein of unknown function UPF0029; KEGG: shm:Shewmr7_0018 protein of unknown function UPF0029 YP_001181551.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: she:Shewmr4_0021 potassium uptake protein, TrkH family YP_001181552.1 KEGG: shm:Shewmr7_0020 protoporphyrinogen oxidase YP_001181553.1 PFAM: regulatory protein, ArsR; KEGG: shm:Shewmr7_0021 transcriptional regulator, ArsR family YP_001181554.1 KEGG: she:Shewmr4_0024 protoporphyrinogen oxidase YP_001181555.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: she:Shewmr4_0025 potassium uptake protein, TrkH family YP_001181556.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001181557.1 TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: she:Shewmr4_0027 sun protein YP_001181558.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: shm:Shewmr7_0026 methionyl-tRNA formyltransferase YP_001181559.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001181560.1 PFAM: Peptidoglycan-binding LysM; KEGG: shm:Shewmr7_0028 peptidoglycan-binding LysM YP_001181561.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: she:Shewmr4_0031 DNA protecting protein DprA YP_001181562.1 PFAM: protein of unknown function DUF494; KEGG: son:SO0035 Smg protein YP_001181563.1 PFAM: DNA topoisomerase, type IA, zn finger domain protein; KEGG: shm:Shewmr7_0031 DNA topoisomerase, type IA, zn finger domain protein YP_001181564.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: son:SO0037 Sua5/YciO/YrdC/YwlC family protein YP_001181565.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001181566.1 PFAM: globin; KEGG: son:SO0039 hypothetical globin YP_001181567.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001181568.1 PFAM: protein of unknown function DUF1488; KEGG: shm:Shewmr7_0036 protein of unknown function DUF1488 YP_001181569.1 KEGG: shm:Shewmr7_0037 carbonic anhydrase, family 3 YP_001181570.1 PFAM: protein of unknown function UPF0153; KEGG: son:SO0044 hypothetical protein YP_001181571.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: she:Shewmr4_0041 transcriptional regulator, BadM/Rrf2 family YP_001181572.1 PFAM: protein of unknown function DUF610, YibQ; KEGG: shm:Shewmr7_0040 protein of unknown function DUF610, YibQ YP_001181573.1 KEGG: she:Shewmr4_0043 carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001181574.1 PFAM: peptidase M23B; KEGG: shm:Shewmr7_0042 peptidase M23B YP_001181575.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001181576.1 PFAM: Rhodanese domain protein; KEGG: shm:Shewmr7_0044 rhodanese domain protein YP_001181577.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001181578.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001181579.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_0049 HI0933 family protein YP_001181580.1 KEGG: sde:Sde_2764 hypothetical protein YP_001181581.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: shm:Shewmr7_0049 potassium uptake protein, TrkH family YP_001181582.1 PFAM: TrkA-N domain protein; KEGG: shm:Shewmr7_0050 TrkA-N domain protein YP_001181583.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO0059 transcriptional regulatory protein KdpE YP_001181584.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: shm:Shewmr7_0052 periplasmic sensor signal transduction histidine kinase YP_001181585.1 PFAM: Pirin domain protein domain protein; Pirin domain protein; KEGG: shm:Shewmr7_0053 pirin domain protein domain protein YP_001181586.1 KEGG: eca:ECA0549 putative plasmid transfer protein YP_001181587.1 PFAM: NLP/P60 protein; KEGG: shm:Shewmr7_0059 NLP/P60 protein YP_001181588.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_001181589.1 KEGG: son:SO0068 hypothetical protein YP_001181590.1 KEGG: son:SO0069 transport protein, putative YP_001181591.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0070 ATP-binding transport protein NatA YP_001181592.1 PFAM: alpha/beta hydrolase fold; TAP domain protein; KEGG: she:Shewmr4_0074 TAP domain protein YP_001181593.1 PFAM: regulatory protein GntR, HTH; KEGG: son:SO0072 transcriptional regulator, GntR family YP_001181594.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0073 ABC transporter, ATP-binding protein YP_001181595.1 KEGG: son:SO0074 hypothetical protein YP_001181596.1 PFAM: AMP-dependent synthetase and ligase; KEGG: she:Shewmr4_0078 AMP-dependent synthetase and ligase YP_001181597.1 KEGG: she:Shewmr4_0079 MORN variant repeat protein YP_001181598.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_0078 thioesterase superfamily protein YP_001181599.1 PFAM: HPP family protein+B94; KEGG: shm:Shewmr7_0079 HPP family protein YP_001181600.1 KEGG: she:Shewmr4_0083 hypothetical protein YP_001181601.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_0081 thioesterase superfamily protein YP_001181602.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: shm:Shewmr7_0084 glutathione-dependent formaldehyde-activating, GFA YP_001181603.1 KEGG: sdn:Sden_0075 hypothetical protein YP_001181604.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO0084 HAD-superfamily hydrolase, subfamily IA, variant 1 family protein YP_001181605.1 KEGG: son:SO0085 hypothetical protein YP_001181606.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: csa:Csal_2061 glycerophosphoryl diester phosphodiesterase YP_001181608.1 KEGG: son:SO0090 hypothetical protein YP_001181609.1 KEGG: shm:Shewmr7_0143 hypothetical protein YP_001181610.1 PFAM: regulatory protein, MarR; KEGG: shm:Shewmr7_0090 transcriptional regulator, MarR family YP_001181611.1 PFAM: Siderophore-interacting protein; FAD-binding 9, siderophore-interacting domain protein; KEGG: shm:Shewmr7_0091 FAD-binding 9, siderophore-interacting domain protein YP_001181612.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_001181613.1 TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein; KEGG: she:Shewmr4_0098 transcriptional regulator, histidine utilization repressor, GntR family YP_001181614.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001181615.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_001181616.1 TIGRFAM: gamma-glutamyl phosphate reductase; KEGG: shm:Shewmr7_3942 gamma-glutamyl phosphate reductase YP_001181617.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001181618.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: shm:Shewmr7_3940 sodium/proline symporter YP_001181619.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001181620.1 KEGG: son:SO4701 hypothetical protein YP_001181621.1 KEGG: son:SO4700 hypothetical protein YP_001181622.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: son:SO4699 oligopeptidase A YP_001181623.1 KEGG: shm:Shewmr7_3934 hypothetical protein YP_001181624.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: she:Shewmr4_3840 glutathione S-transferase, N-terminal domain protein YP_001181625.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_3837 efflux transporter, RND family, MFP subunit YP_001181626.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: son:SO4692 AcrB/AcrD/AcrF family protein YP_001181627.1 KEGG: she:Shewmr4_3835 hypothetical protein YP_001181628.1 KEGG: shm:Shewmr7_3927 hypothetical protein YP_001181629.1 PFAM: C4-dicarboxylate anaerobic carrier; AbgT putative transporter; KEGG: she:Shewmr4_3833 AbgT putative transporter YP_001181630.1 PFAM: LemA family protein; KEGG: son:SO4662 lemA protein YP_001181631.1 PFAM: Lytic transglycosylase, catalytic; KEGG: son:SO4660 transglycosylase SLT domain protein YP_001181632.1 KEGG: she:Shewmr4_1960 hypothetical protein YP_001181633.1 PFAM: protein of unknown function DUF519; KEGG: shm:Shewmr7_3922 protein of unknown function DUF519 YP_001181634.1 PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: pat:Patl_2246 diguanylate cyclase/phosphodiesterase YP_001181635.1 PFAM: protein of unknown function DUF548; KEGG: shm:Shewmr7_3921 protein of unknown function DUF548 YP_001181637.1 KEGG: pol:Bpro_1650 hypothetical protein YP_001181639.1 PFAM: acriflavin resistance protein; KEGG: csa:Csal_2405 acriflavin resistance protein YP_001181640.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: hne:HNE_2191 efflux transporter, RND family, MFP subunit YP_001181641.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: rru:Rru_A1440 TonB-dependent siderophore receptor YP_001181642.1 PFAM: peptidase M48, Ste24p; KEGG: son:SO0110 hypothetical protease YP_001181643.1 KEGG: shm:Shewmr7_0108 hypothetical protein YP_001181644.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ppr:PBPRA1918 putative glyoxalase family protein YP_001181645.1 KEGG: shm:Shewmr7_0110 hypothetical protein YP_001181646.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: yps:YPTB1207 putative transcriptional regulator, LysR family YP_001181647.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001181649.1 PFAM: cytochrome c biogenesis protein, transmembrane region; KEGG: vpa:VP2006 putative suppressor for copper-sensitivity B precursor YP_001181650.1 PFAM: DSBA oxidoreductase; KEGG: vfi:VF2492 copper sensitivity protein ScsC YP_001181651.1 PFAM: Redoxin domain protein; KEGG: ppr:PBPRB1492 hypothetical thioredoxin YP_001181652.1 PFAM: protein of unknown function DUF1090; KEGG: son:SO0119 hypothetical protein YP_001181653.1 PFAM: MscS Mechanosensitive ion channel; KEGG: shm:Shewmr7_0112 MscS mechanosensitive ion channel YP_001181654.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shm:Shewmr7_0113 lysine exporter protein (LysE/YggA) YP_001181655.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: shm:Shewmr7_0114 phospholipid/glycerol acyltransferase YP_001181656.1 KEGG: shm:Shewmr7_0115 hypothetical protein YP_001181657.1 PFAM: protein of unknown function DUF833; KEGG: shm:Shewmr7_0116 protein of unknown function DUF833 YP_001181658.1 KEGG: shm:Shewmr7_0117 hypothetical protein YP_001181659.1 PFAM: multiple antibiotic resistance (MarC)-related proteins; KEGG: son:SO0129 conserved hypothetical protein TIGR00427 YP_001181660.1 PFAM: PKD domain containing protein; peptidase M6, immune inhibitor A; KEGG: shm:Shewmr7_0119 peptidase M6, immune inhibitor A YP_001181661.1 PFAM: Chorismate lyase; KEGG: son:SO0131 putative chorismate--pyruvate lyase YP_001181662.1 PFAM: flagellar basal body-associated protein FliL; KEGG: she:Shewmr4_0127 flagellar basal body-associated protein FliL YP_001181663.1 PFAM: protein of unknown function DUF890; KEGG: shm:Shewmr7_0122 protein of unknown function DUF890 YP_001181664.1 KEGG: she:Shewmr4_0130 hypothetical protein YP_001181665.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001181666.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV; KEGG: shm:Shewmr7_0126 molybdenum cofactor synthesis domain YP_001181667.1 PFAM: Ferritin, Dps family protein; KEGG: son:SO0139 ferritin YP_001181668.1 KEGG: shm:Shewmr7_0128 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001181669.1 DHBP synthase; functions during riboflavin biosynthesis YP_001181670.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller; KEGG: she:Shewmr4_0136 oligopeptidase B YP_001181671.1 PFAM: Excinuclease ABC, C subunit domain protein; KEGG: shm:Shewmr7_0131 excinuclease ABC, C subunit domain protein YP_001181672.1 KEGG: she:Shewmr4_2140 hypothetical protein YP_001181674.1 KEGG: shm:Shewmr7_0137 hypothetical protein YP_001181675.1 KEGG: shm:Shewmr7_0137 hypothetical protein YP_001181676.1 KEGG: shm:Shewmr7_0138 lipoprotein, putative YP_001181677.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_0139 methyltransferase type 11 YP_001181678.1 PFAM: peptidase M14, carboxypeptidase A; KEGG: she:Shewmr4_0145 peptidase M14, carboxypeptidase A YP_001181679.1 KEGG: shm:Shewmr7_0141 hypothetical protein YP_001181680.1 PFAM: sodium:dicarboxylate symporter; KEGG: she:Shewmr4_0147 sodium:dicarboxylate symporter YP_001181682.1 PFAM: AbgT putative transporter; short chain fatty acid transporter; KEGG: son:SO0160 transporter, putative YP_001181683.1 KEGG: gme:Gmet_1465 hypothetical protein YP_001181684.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: son:SOA0153 heavy metal efflux pump, CzcA family YP_001181685.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: son:SOA0154 heavy metal efflux protein, putative YP_001181686.1 KEGG: she:Shewmr4_3781 copper-transporting ATPase domain protein YP_001181687.1 KEGG: son:SOA0156 hypothetical protein YP_001181688.1 KEGG: cps:CPS_2062 site-specific recombinase, phage integrase family YP_001181689.1 KEGG: neu:NE0385 site-specific DNA-methyltransferase, type I modification YP_001181690.1 SMART: AAA ATPase; KEGG: bps:BPSL3342 putative bacteriophage protein YP_001181691.1 PFAM: protein of unknown function DUF45; KEGG: yps:YPTB3878 putative predicted metal-dependent hydrolase YP_001181692.1 KEGG: yps:YPTB3879 possible type I restriction enzyme (restriction subunit); TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like YP_001181693.1 PFAM: KAP P-loop domain protein; KEGG: vpa:VP2903 hypothetical protein YP_001181694.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_001181695.1 PFAM: restriction modification system DNA specificity domain; KEGG: tde:TDE0368 type I restriction-modification system, S subunit, putative YP_001181696.1 TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; KEGG: dvu:DVU1709 type I restriction-modification system, M subunit YP_001181697.1 KEGG: xcb:XC_1208 hypothetical protein YP_001181699.1 KEGG: ana:alr8025 unknown protein YP_001181700.1 SMART: AAA ATPase; KEGG: psp:PSPPH_B0059 ExeA-like protein YP_001181701.1 KEGG: stm:PSLT044 putative integrase protein YP_001181702.1 PFAM: Resolvase, N-terminal domain; Resolvase helix-turn-helix domain protein; KEGG: xac:XACb0071 Tn5045 resolvase YP_001181703.1 TIGRFAM: mercuric reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; Heavy metal transport/detoxification protein; KEGG: sfr:Sfri_3488 mercuric reductase YP_001181704.1 TIGRFAM: mercuric transport protein periplasmic component; PFAM: Heavy metal transport/detoxification protein; KEGG: sfr:Sfri_3490 mercuric transport protein periplasmic component YP_001181705.1 PFAM: Mercuric transport protein MerT; KEGG: sfr:Sfri_3491 mercuric transport protein MerT YP_001181706.1 TIGRFAM: Hg(II)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; KEGG: sfr:Sfri_3492 transcriptional regulator, MerR family protein YP_001181707.1 PFAM: UMUC domain protein DNA-repair protein; KEGG: son:SOA0012 umuC protein YP_001181708.1 PFAM: Integrase, catalytic region; KEGG: vpa:VP1787 putative transposase YP_001181709.1 PFAM: transposase IS3/IS911 family protein; KEGG: vpa:VP1788 putative transposase YP_001181710.1 PFAM: peptidase S24, S26A and S26B; KEGG: son:SOA0013 umuD protein YP_001181711.1 KEGG: psp:PSPPH_A0095 plasmid stabilization system protein, RelE/ParE family YP_001181712.1 TIGRFAM: prevent-host-death family protein; KEGG: vpa:VP1886 hypothetical protein YP_001181713.1 PFAM: phage integrase family protein; KEGG: jan:Jann_1536 phage integrase YP_001181714.1 KEGG: gme:Gmet_2490 hypothetical protein YP_001181716.1 KEGG: son:SOA0069 hypothetical protein YP_001181717.1 KEGG: son:SOA0068 putative transcriptional regulator YP_001181720.1 KEGG: eca:ECA2757 hypothetical protein YP_001181721.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sfr:Sfri_0790 sulphate transporter YP_001181722.1 PFAM: UspA domain protein; KEGG: sfr:Sfri_0791 UspA domain protein YP_001181723.1 KEGG: sil:SPO2248 DnaK suppressor protein, putative YP_001181724.1 PFAM: Resolvase, N-terminal domain; KEGG: sfr:Sfri_3477 resolvase, N-terminal domain protein YP_001181725.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: sfr:Sfri_3472 prevent-host-death family protein YP_001181726.1 PFAM: plasmid stabilization system; KEGG: sfr:Sfri_3471 plasmid stabilization system YP_001181727.1 PFAM: transposase Tn3 family protein; KEGG: sfr:Sfri_3470 transposase Tn3 family protein YP_001181728.1 KEGG: pol:Bpro_2488 cointegrate resolution protein T YP_001181729.1 TIGRFAM: Cd(II)/Pb(II)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; KEGG: abo:ABO_1367 transcriptional regulator, MerR family YP_001181730.1 KEGG: abo:ABO_1368 cation efflux system permease, putative YP_001181731.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001181732.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein; KEGG: bxe:Bxe_C0885 transposase, TnpA YP_001181733.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: sec:SC2060 propanediol utilization: propanol dehydrogenase YP_001181734.1 PFAM: aldehyde dehydrogenase; KEGG: stm:STM2051 CoA-dependent propionaldehyde dehydrogenase YP_001181735.1 KEGG: ccr:CC2181 GlcG protein, putative YP_001181736.1 PFAM: Ethanolamine utilization protein EutN/carboxysome structural protein Ccml; KEGG: ssn:SSO_2069 putative propanediol utilization protein: polyhedral bodies YP_001181737.1 KEGG: sec:SC2056 propanediol utilization YP_001181738.1 PFAM: Propanediol utilization protein; KEGG: sec:SC2055 propanediol utilization YP_001181739.1 PFAM: microcompartments protein; KEGG: stt:t0828 putative propanediol utilization protein PduK YP_001181740.1 PFAM: microcompartments protein; KEGG: ssn:SSO_2065 putative propanediol utilization protein: polyhedral bodies YP_001181741.1 TIGRFAM: MIP family channel proteins; PFAM: major intrinsic protein; KEGG: stm:STM2037 Propanediol utilization: propanediol diffusion facilitator YP_001181742.1 TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Radical SAM domain protein; KEGG: ecc:c4538 putative pyruvate formate-lyase 3 activating enzyme YP_001181743.1 KEGG: ctc:CTC00936 formate acetyltransferase 2; TIGRFAM: pyruvate formate-lyase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL YP_001181744.1 PFAM: microcompartments protein; KEGG: sec:SC2047 propanediol utilization: polyhedral bodies YP_001181745.1 PFAM: microcompartments protein; KEGG: ssn:SSO_2058 putative propanediol utilization protein: polyhedral bodies YP_001181746.1 TIGRFAM: PTS system, mannose/fructose/sorbose family, IID subunit; PFAM: PTS system mannose/fructose/sorbose family IID component; KEGG: bsu:BG10319 PTS fructose-specific enzyme IID component YP_001181747.1 TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC subunit; PFAM: phosphotransferase system PTS, sorbose-specific IIC subunit; KEGG: bld:BLi02829 PTS fructose-specific enzyme IIC component; RBL00186 YP_001181748.1 PFAM: PTS system sorbose subfamily IIB component; KEGG: bsu:BG10317 PTS fructose-specific enzyme IIB component YP_001181749.1 PFAM: transposase, IS4 family protein; KEGG: sgl:SG1040 transposase YP_001181750.1 PFAM: IS1 transposase; KEGG: sec:SC1834 IS1 transposase YP_001181751.1 PFAM: Insertion element protein; KEGG: sec:SC062 transposition protein YP_001181752.1 PFAM: phage integrase family protein; KEGG: ecc:c0291 hypothetical protein YP_001181753.1 KEGG: sbo:SBO_P069 IS630 ORF YP_001181754.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: stm:STM2036 Propanediol utilization: transcriptional regulation, AraC family YP_001181755.1 TIGRFAM: Cd(II)/Pb(II)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; KEGG: abo:ABO_1367 transcriptional regulator, MerR family YP_001181756.1 KEGG: abo:ABO_1368 cation efflux system permease, putative YP_001181757.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001181758.1 PFAM: transposase, IS204/IS1001/IS1096/IS1165 family protein; KEGG: bxe:Bxe_C0885 transposase, TnpA YP_001181759.1 KEGG: sdn:Sden_0608 hypothetical protein YP_001181760.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: sde:Sde_1955 cation efflux system protein YP_001181761.1 PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: sde:Sde_1956 hypothetical protein YP_001181762.1 PFAM: outer membrane efflux protein; KEGG: sde:Sde_1958 aconitate hydratase 1 YP_001181764.1 KEGG: abo:ABO_1368 cation efflux system permease, putative YP_001181765.1 TIGRFAM: Cd(II)/Pb(II)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; KEGG: sde:Sde_1961 putative transcriptional regulator, MerR family YP_001181766.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: tcx:Tcr_1429 cation diffusion facilitator family transporter YP_001181767.1 PFAM: protein of unknown function UPF0060; KEGG: abo:ABO_1373 hypothetical protein YP_001181770.1 KEGG: ppr:PBPRA1708 hypothetical protein YP_001181772.1 PFAM: phage integrase family protein; KEGG: ppr:PBPRB0929 hypothetical protein YP_001181773.1 KEGG: shm:Shewmr7_2032 hypothetical protein YP_001181778.1 KEGG: son:SO2875 ISSod10, transposase OrfB YP_001181779.1 KEGG: son:SO4533 ISSod10, transposase OrfA YP_001181780.1 PFAM: transposase, IS4 family protein; KEGG: plu:plu3796 hypothetical protein YP_001181781.1 KEGG: sfr:Sfri_1967 hypothetical protein YP_001181782.1 PFAM: protein of unknown function DUF411; KEGG: sfr:Sfri_1968 protein of unknown function DUF411 YP_001181783.1 TIGRFAM: copper-resistance protein, CopA family; PFAM: multicopper oxidase, type 1; multicopper oxidase, type 2; multicopper oxidase, type 3; KEGG: sfr:Sfri_1969 copper-resistance protein, CopA family protein YP_001181784.1 PFAM: copper resistance B precursor; KEGG: sfr:Sfri_1970 copper resistance B precursor YP_001181785.1 PFAM: copper resistance protein CopC; KEGG: sfr:Sfri_1971 copper resistance protein CopC YP_001181786.1 PFAM: copper resistance D domain protein; KEGG: sfr:Sfri_1972 copper resistance D domain protein YP_001181787.1 KEGG: sfr:Sfri_1973 putative orphan protein YP_001181788.1 KEGG: oih:OB3301 hypothetical protein YP_001181789.1 PFAM: outer membrane porin; KEGG: wsu:WS0983 hypothetical protein YP_001181790.1 KEGG: son:SO2129 transposase, putative YP_001181791.1 TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: ecs:ECs0608 putative 2-component sensor protein YP_001181792.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system YP_001181793.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_001181794.1 KEGG: ecj:JW0562 periplasmic copper-binding protein YP_001181795.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_001181796.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: ecp:ECP_0606 putative cation efflux system protein CusA YP_001181797.1 PFAM: protein of unknown function DUF411; KEGG: mca:MCA0560 hypothetical protein YP_001181798.1 KEGG: sal:Sala_2544 heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; YHS domain protein; E1-E2 ATPase-associated domain protein; SMART: TRASH domain protein YP_001181799.1 KEGG: cvi:CV3215 hypothetical protein YP_001181800.1 PFAM: peptidase M23B; KEGG: stm:STM1890 putative peptidase YP_001181801.1 KEGG: spt:SPA2166 possible copper-binding protein YP_001181802.1 KEGG: sfr:Sfri_0213 likely secreted protein containing plastocyanin domain YP_001181803.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: sfr:Sfri_0212 copper-translocating P-type ATPase YP_001181804.1 PFAM: regulatory protein, MerR; KEGG: sfr:Sfri_0211 transcriptional regulator, MerR family protein YP_001181805.1 KEGG: sfr:Sfri_1966 hypothetical protein YP_001181806.1 KEGG: sfr:Sfri_1965 hypothetical protein YP_001181807.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); Group II intron, maturase-specific domain protein; KEGG: sme:SMb21045 putative reverse transcriptasematurase protein YP_001181808.1 PFAM: Integrase, catalytic region; KEGG: vch:VCA0791 transposase OrfAB, subunit B YP_001181809.1 PFAM: transposase IS3/IS911 family protein; KEGG: vch:VCA0792 transposase OrfAB, subunit A YP_001181810.1 KEGG: ade:Adeh_2330 hypothetical protein YP_001181811.1 KEGG: vfi:VFA1085 hypothetical protein YP_001181812.1 KEGG: cps:CPS_2062 site-specific recombinase, phage integrase family YP_001181813.1 KEGG: gme:Gmet_1465 hypothetical protein YP_001181814.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: son:SOA0153 heavy metal efflux pump, CzcA family YP_001181815.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: son:SOA0154 heavy metal efflux protein, putative YP_001181816.1 KEGG: son:SOA0155 hypothetical protein YP_001181817.1 KEGG: son:SOA0156 hypothetical protein YP_001181818.1 PFAM: NapC/NirT cytochrome c domain protein; KEGG: son:SO4591 tetraheme cytochrome c YP_001181819.1 PFAM: protein of unknown function DUF1145; KEGG: son:SO4588 hypothetical protein YP_001181820.1 TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: she:Shewmr4_3775 putative methyltransferase YP_001181821.1 KEGG: son:SO4586 cell division protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54, G- domain; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase YP_001181822.1 KEGG: shm:Shewmr7_3846 cell division ATP-binding protein FtsE; TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter related; SMART: AAA ATPase YP_001181823.1 PFAM: protein of unknown function DUF214; KEGG: she:Shewmr4_3772 protein of unknown function DUF214 YP_001181824.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001181825.1 PFAM: Fimbrial protein; KEGG: bam:Bamb_2833 fimbrial protein YP_001181826.1 KEGG: yps:YPTB0157 hypothetical protein YP_001181828.1 KEGG: pau:PA14_59750 fimbrial subunit YP_001181829.1 PFAM: Fimbrial protein; KEGG: bam:Bamb_2833 fimbrial protein YP_001181830.1 PFAM: pili assembly chaperone; KEGG: ypn:YPN_0086 fimbrial chaperone YP_001181831.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: pae:PA2130 probable fimbrial biogenesis usher protein YP_001181832.1 KEGG: pau:PA14_59750 fimbrial subunit YP_001181833.1 PFAM: pili assembly chaperone; KEGG: rme:Rmet_1663 pili assembly chaperone YP_001181834.1 KEGG: psb:Psyr_2113 PAS; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; extracellular solute-binding protein, family 3 YP_001181835.1 PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: pfo:Pfl_4515 two component transcriptional regulator, LuxR family YP_001181836.1 PFAM: EAL domain protein; response regulator receiver; KEGG: pau:PA14_12810 probable two-component response regulator YP_001181837.1 KEGG: she:Shewmr4_2113 hypothetical protein YP_001181838.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: son:SO4576 O-succinylbenzoic acid--CoA ligase YP_001181839.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_001181840.1 PFAM: alpha/beta hydrolase fold; KEGG: she:Shewmr4_3768 alpha/beta hydrolase fold YP_001181841.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_001181842.1 PFAM: regulatory protein, LysR; KEGG: shm:Shewmr7_3839 transcriptional regulator, LysR family YP_001181843.1 KEGG: she:Shewmr4_3765 hypothetical protein YP_001181844.1 KEGG: she:Shewmr4_3764 formate-dependent nitrite reductase YP_001181845.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: she:Shewmr4_3763 twin-arginine translocation pathway signal YP_001181846.1 PFAM: Polysulphide reductase, NrfD; KEGG: son:SO4568 formate-dependent nitrite reductase, nrfD protein YP_001181847.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: son:SO4567 transcriptional regulator, AsnC family YP_001181848.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_001181849.1 PFAM: protein of unknown function DUF1332; KEGG: shm:Shewmr7_3830 protein of unknown function DUF1332 YP_001181850.1 KEGG: she:Shewmr4_3756 hypothetical protein YP_001181851.1 KEGG: shm:Shewmr7_3828 hypothetical protein YP_001181852.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: she:Shewmr4_3754 Sel1 domain protein repeat-containing protein YP_001181853.1 KEGG: shm:Shewmr7_3826 hypothetical protein YP_001181854.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: son:SO4557 methyl-accepting chemotaxis protein YP_001181855.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO4556 transcriptional regulator, LysR family YP_001181856.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: son:SO4555 drug resistance transporter, Bcr/CflA family protein YP_001181857.1 PFAM: DTW domain containing protein; KEGG: son:SO4554 hypothetical protein YP_001181858.1 KEGG: son:SO4552 sensory box protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001181859.1 KEGG: she:Shewmr4_3747 hypothetical protein YP_001181860.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_3819 methyltransferase type 11 YP_001181861.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_3798 TonB-dependent receptor YP_001181862.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: she:Shewmr4_3726 formate dehydrogenase, gamma subunit YP_001181863.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_3796 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001181864.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: shm:Shewmr7_3795 twin-arginine translocation pathway signal YP_001181865.1 KEGG: shm:Shewmr7_3794 twin-arginine translocation pathway signal YP_001181866.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: shm:Shewmr7_3793 formate dehydrogenase, gamma subunit YP_001181867.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4510 formate dehydrogenase, iron-sulfur subunit YP_001181868.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: son:SO4509 formate dehydrogenase, alpha subunit YP_001181869.1 KEGG: son:SO4508 hypothetical protein YP_001181870.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: shm:Shewmr7_3789 cytoplasmic chaperone TorD family protein YP_001181871.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4506 iron-sulfur cluster-binding protein YP_001181872.1 KEGG: shm:Shewmr7_3787 hypothetical protein YP_001181873.1 KEGG: son:SO4504 hypothetical protein YP_001181874.1 PFAM: formate dehydrogenase, subunit FdhD; KEGG: she:Shewmr4_3714 formate dehydrogenase, subunit FdhD YP_001181875.1 TIGRFAM: DNA binding domain, excisionase family; KEGG: she:Shewmr4_3713 DNA binding domain, excisionase family YP_001181876.1 KEGG: shm:Shewmr7_3783 hypothetical protein YP_001181877.1 KEGG: son:SO4490 hypothetical protein YP_001181878.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; KEGG: bsu:BG12951 similar to 2-oxoglutarate/malate translocator YP_001181879.1 TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; Fe-S type hydro-lyases tartrate/fumarate beta region; KEGG: ppr:PBPRA2409 putative fumarate hydratase, class I YP_001181880.1 PFAM: response regulator receiver; Helix-turn-helix, type 11 domain protein; KEGG: vpa:VP1711 response regulator YP_001181881.1 PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: bld:BLi01245 hypothetical protein YP_001181882.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_001181883.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001181884.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001181885.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001181886.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO4489 acetyltransferase, GNAT family YP_001181887.1 PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: son:SO4488 sensor histidine kinase YP_001181888.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO4487 DNA-binding response regulator YP_001181889.1 PFAM: Propeptide, PepSY amd peptidase M4; KEGG: shm:Shewmr7_3780 propeptide, PepSY amd peptidase M4 YP_001181890.1 KEGG: son:SO4485 diheme cytochrome c YP_001181891.1 KEGG: shm:Shewmr7_3778 cytochrome c-type protein Shp YP_001181892.1 PFAM: cytochrome B561; KEGG: she:Shewmr4_0244 cytochrome b561 YP_001181893.1 KEGG: she:Shewmr4_0245 hypothetical protein YP_001181894.1 KEGG: son:SO4481 hypothetical protein YP_001181895.1 PFAM: aldehyde dehydrogenase; KEGG: son:SO4480 aldehyde dehydrogenase YP_001181896.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3771 GAF modulated sigma54 specific transcriptional regulator, fis family YP_001181897.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4478 sensor protein CpxA YP_001181898.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO4477 transcriptional regulatory protein CpxR YP_001181899.1 PFAM: protein of unknown function, Spy-related; KEGG: she:Shewmr4_0253 protein of unknown function, Spy-related YP_001181900.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: shm:Shewmr7_3767 cation diffusion facilitator family transporter YP_001181901.1 KEGG: she:Shewmr4_0255 hypothetical protein YP_001181902.1 KEGG: shm:Shewmr7_3764 nitrogen metabolism transcriptional regulator, NtrC, fis family; TIGRFAM: nitrogen regulation protein NR(I); PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001181903.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; KEGG: shm:Shewmr7_3763 signal transduction histidine kinase, nitrogen specific, NtrB YP_001181904.1 KEGG: shm:Shewmr7_3762 hypothetical protein YP_001181905.1 KEGG: sdn:Sden_1385 glutathione S-transferase-like protein YP_001181906.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: vvu:VV20508 glutathione S-transferase YP_001181907.1 PFAM: ThiJ/PfpI domain protein; KEGG: psb:Psyr_3319 ThiJ/PfpI YP_001181908.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: son:SO4469 alcohol dehydrogenase, iron-containing YP_001181909.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_3760 transcriptional regulator, TetR family YP_001181910.1 PFAM: protein of unknown function DUF1255; KEGG: shm:Shewmr7_3759 protein of unknown function DUF1255 YP_001181911.1 PFAM: chemotaxis sensory transducer; KEGG: shm:Shewmr7_3758 methyl-accepting chemotaxis sensory transducer YP_001181912.1 PFAM: protein of unknown function DUF323; Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_3757 protein of unknown function DUF323 YP_001181913.1 KEGG: she:Shewmr4_0265 hypothetical protein YP_001181914.1 PFAM: PfkB domain protein; KEGG: son:SO4458 carbohydrate kinase, PfkB family YP_001181915.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO4457 GGDEF domain protein YP_001181916.1 PFAM: 3-alpha; MOSC domain containing protein; KEGG: she:Shewmr4_0269 MOSC domain containing protein YP_001181917.1 KEGG: shm:Shewmr7_3751 hypothetical protein YP_001181918.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_3750 methyl-accepting chemotaxis sensory transducer YP_001181919.1 PFAM: FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase; KEGG: shm:Shewmr7_3749 electron-transferring-flavoprotein dehydrogenase YP_001181920.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001181921.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001181922.1 TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: son:SO4450 molybdenum cofactor biosynthesis protein D YP_001181923.1 PFAM: molybdopterin biosynthesis MoaE; KEGG: she:Shewmr4_0276 molybdopterin biosynthesis MoaE YP_001181924.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; KEGG: she:Shewmr4_0277 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_001181925.1 TIGRFAM: molybdate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_3743 molybdate ABC transporter, inner membrane subunit YP_001181926.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_3742 ABC transporter related YP_001181927.1 KEGG: shm:Shewmr7_3741 hypothetical protein YP_001181928.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO4428 DNA-binding response regulator YP_001181929.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4427 sensor histidine kinase YP_001181930.1 TIGRFAM: pseudouridine synthase Rlu family protein, TIGR01621; PFAM: pseudouridine synthase; KEGG: she:Shewmr4_0283 pseudouridine synthase Rlu family protein, TIGR01621 YP_001181931.1 PFAM: protein of unknown function UPF0057; KEGG: shm:Shewmr7_3736 protein of unknown function UPF0057 YP_001181932.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_0286 TonB-dependent receptor YP_001181933.1 KEGG: son:SO4421 hypothetical protein YP_001181934.1 PFAM: peptidase M23B; KEGG: son:SO4420 peptidase, M23/M37 family YP_001181935.1 KEGG: son:SO4419 hypothetical protein YP_001181936.1 PFAM: CHAP domain containing protein; KEGG: son:SO4418 trypanothione synthetase domain protein YP_001181937.1 KEGG: she:Shewmr4_0294 hypothetical protein YP_001181938.1 PFAM: aminotransferase, class V; KEGG: shm:Shewmr7_3724 aminotransferase, class V YP_001181939.1 KEGG: son:SO4412 hypothetical protein YP_001181940.1 KEGG: she:Shewmr4_1960 hypothetical protein YP_001181941.1 KEGG: vch:VCA0021 hypothetical protein YP_001181942.1 KEGG: vch:VCA0021 hypothetical protein YP_001181943.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_001181944.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; KEGG: son:SO4408 virulence regulator BipA YP_001181945.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO4407 GGDEF family protein YP_001181946.1 KEGG: she:Shewmr4_0311 catalase/peroxidase HPI; TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase YP_001181947.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_3712 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001181948.1 KEGG: shm:Shewmr7_3709 hypothetical protein YP_001181949.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_001181950.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001181951.1 TIGRFAM: thioesterase domain, putative; KEGG: son:SO4397 hypothetical acetyltransferase YP_001181952.1 PFAM: peptidase S1 and S6, chymotrypsin/Hap; KEGG: mag:amb2240 TPR repeat YP_001181954.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_001181955.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; KEGG: shm:Shewmr7_3700 transcriptional regulator, XRE family YP_001181956.1 TIGRFAM: benzoate transporter; PFAM: Benzoate membrane transport protein; Xanthine/uracil/vitamin C permease; KEGG: shm:Shewmr7_3699 benzoate transporter YP_001181957.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_3696 GCN5-related N-acetyltransferase YP_001181958.1 KEGG: she:Shewmr4_3023 hypothetical protein YP_001181959.1 PFAM: plasmid stabilization system; KEGG: she:Shewmr4_0332 plasmid stabilization system YP_001181960.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: shm:Shewmr7_3693 prevent-host-death family protein YP_001181961.1 KEGG: she:Shewmr4_0334 hypothetical protein YP_001181962.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001181963.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001181964.1 KEGG: son:SO4381 thioester dehydrase family protein YP_001181965.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001181966.1 KEGG: she:Shewmr4_0339 hypothetical protein YP_001181967.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; tryptophan halogenase; KEGG: shm:Shewmr7_3686 monooxygenase, FAD-binding protein YP_001181968.1 KEGG: she:Shewmr4_0341 hypothetical protein YP_001181969.1 KEGG: son:SO4376 hypothetical protein YP_001181970.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_3683 thioesterase superfamily protein YP_001181971.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: she:Shewmr4_0344 histidine ammonia-lyase YP_001181972.1 PFAM: glycosyl transferase, family 2; lipid A biosynthesis acyltransferase; KEGG: shm:Shewmr7_3681 glycosyl transferase, family 2 YP_001181973.1 KEGG: son:SO4372 thioester dehydrase family protein YP_001181974.1 KEGG: shm:Shewmr7_3679 hypothetical protein YP_001181975.1 KEGG: son:SO4370 hypothetical protein YP_001181976.1 carries the fatty acid chain in fatty acid biosynthesis YP_001181977.1 KEGG: son:SO4368 acyl carrier protein, putative YP_001181978.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: she:Shewmr4_0351 phospholipid/glycerol acyltransferase YP_001181979.1 KEGG: she:Shewmr4_0352 hypothetical protein YP_001181980.1 KEGG: son:SO4365 hypothetical protein YP_001181981.1 catalyzes branch migration in Holliday junction intermediates YP_001181982.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function YP_001181983.1 PFAM: OmpA/MotB domain protein; KEGG: she:Shewmr4_0916 OmpA/MotB domain protein YP_001181986.1 PFAM: YicC N-terminal domain protein; domain of unknown function DUF1732; KEGG: shm:Shewmr7_0351 hypothetical protein YP_001181987.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001181988.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001181989.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001181990.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_001181991.1 catalyzes the formation of dUMP from dUTP YP_001181992.1 KEGG: shm:Shewmr7_0358 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein YP_001181993.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001181994.1 required for 70S ribosome assembly YP_001181995.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001181996.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_001181997.1 KEGG: son:SO4244 hypothetical protein YP_001181998.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6, transmembrane; KEGG: son:SO4243 rarD protein YP_001181999.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: she:Shewmr4_3591 uncharacterized domain 1 YP_001182000.1 KEGG: she:Shewmr4_3590 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001182001.1 SMART: Tetratricopeptide domain protein; KEGG: she:Shewmr4_3589 response regulator receiver protein YP_001182002.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001182003.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001182004.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001182005.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001182006.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: shm:Shewmr7_0372 membrane protein involved in aromatic hydrocarbon degradation YP_001182007.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase, FGGY; KEGG: son:SO4230 glycerol kinase YP_001182008.1 KEGG: shm:Shewmr7_0374 hypothetical protein YP_001182009.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001182010.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: shm:Shewmr7_0378 S-adenosyl-methyltransferase MraW YP_001182011.1 PFAM: cell division protein FtsL; KEGG: she:Shewmr4_3577 cell division protein FtsL YP_001182012.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: son:SO4225 peptidoglycan synthetase FtsI YP_001182013.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001182014.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: son:SO4223 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanine ligase YP_001182015.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001182016.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001182017.1 TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: son:SO4220 cell division protein FtsW YP_001182018.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001182019.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001182020.1 PFAM: cell division protein FtsQ; Polypeptide-transport-associated domain protein, FtsQ-type; KEGG: shm:Shewmr7_0388 polypeptide-transport-associated domain protein, FtsQ-type YP_001182021.1 PFAM: cell division protein FtsA; KEGG: shm:Shewmr7_0389 cell division protein FtsA YP_001182022.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001182023.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001182024.1 KEGG: shm:Shewmr7_0392 hypothetical protein YP_001182025.1 PFAM: peptidase M23B; KEGG: shm:Shewmr7_0393 peptidase M23B YP_001182026.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001182027.1 KEGG: sfr:Sfri_1559 ISSod10, transposase OrfB YP_001182028.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001182029.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Diverse 7TM receptor, extracellular region 2; Diverse 7TM receptor, transmembrane region; KEGG: son:SO4207 GGDEF domain protein YP_001182030.1 PFAM: TatD-related deoxyribonuclease; KEGG: shm:Shewmr7_0398 TatD-related deoxyribonuclease YP_001182031.1 KEGG: son:SO4205 hypothetical protein YP_001182032.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: she:Shewmr4_3556 sec-independent protein translocase, TatC subunit YP_001182033.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; KEGG: shm:Shewmr7_0401 twin-arginine translocation protein, TatB subunit YP_001182034.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: shm:Shewmr7_0402 twin-arginine translocation protein, TatA/E family subunit YP_001182035.1 TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: ABC-1 domain protein; KEGG: shm:Shewmr7_0403 2-polyprenylphenol 6-hydroxylase YP_001182036.1 PFAM: protein of unknown function DUF1243; KEGG: she:Shewmr4_3552 protein of unknown function DUF1243 YP_001182037.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferases; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO4199 ubiquinone/menaquinone biosynthesis methlytransferase UbiE YP_001182038.1 PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: she:Shewmr4_3550 arginase/agmatinase/formiminoglutamase YP_001182039.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001182040.1 KEGG: shm:Shewmr7_0408 hypothetical protein YP_001182041.1 PFAM: phosphoesterase, PA-phosphatase related; KEGG: son:SO4195 PAP2 family protein YP_001182042.1 KEGG: shm:Shewmr7_0410 hypothetical protein YP_001182043.1 KEGG: she:Shewmr4_3545 hypothetical protein YP_001182044.1 PFAM: chemotaxis sensory transducer; KEGG: ilo:IL1068 methyl-accepting chemotaxis protein with ligand-binding sensor domain and HAMP domain YP_001182045.1 KEGG: shm:Shewmr7_0412 DedA family protein YP_001182046.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001182047.1 PFAM: conserved hypothetical protein 22; KEGG: shm:Shewmr7_0414 conserved hypothetical protein 22 YP_001182048.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_3540 TonB-dependent receptor YP_001182049.1 KEGG: son:SO4182 ATP-dependent protease La (LON) domain protein, putative YP_001182050.1 PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_0418 pseudouridine synthase YP_001182051.1 PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: she:Shewmr4_3530 periplasmic sensor signal transduction histidine kinase YP_001182052.1 PFAM: response regulator receiver; helix-turn-helix, Fis-type; KEGG: she:Shewmr4_3529 response regulator receiver protein YP_001182053.1 KEGG: she:Shewmr4_3528 hypothetical protein YP_001182054.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: she:Shewmr4_3527 short-chain dehydrogenase/reductase SDR YP_001182055.1 PFAM: deoxyribodipyrimidine photolyase-related protein; KEGG: son:SO4169 hypothetical protein YP_001182057.1 KEGG: shm:Shewmr7_0431 hypothetical protein YP_001182058.1 PFAM: protein of unknown function DUF971; KEGG: she:Shewmr4_3523 protein of unknown function DUF971 YP_001182059.1 heat shock protein involved in degradation of misfolded proteins YP_001182060.1 heat shock protein involved in degradation of misfolded proteins YP_001182061.1 KEGG: son:SO4159 hypothetical protein YP_001182062.1 PFAM: bifunctional deaminase-reductase domain protein; KEGG: lpn:lpg1988 dihydrofolate reductase YP_001182063.1 KEGG: she:Shewmr4_3518 hypothetical protein YP_001182064.1 KEGG: son:SO4160 flagellar biosynthesis protein, putative YP_001182065.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: shm:Shewmr7_0436 two component transcriptional regulator, LuxR family YP_001182066.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_3516 histidine kinase YP_001182067.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: son:SO4150 transporter, putative YP_001182068.1 KEGG: pat:Patl_1924 hypothetical protein YP_001182069.1 KEGG: son:SO4139 hypothetical protein YP_001182070.1 PFAM: MscS Mechanosensitive ion channel; KEGG: she:Shewmr4_3509 MscS mechanosensitive ion channel YP_001182071.1 KEGG: shm:Shewmr7_0444 hypothetical protein YP_001182072.1 PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: son:SO4136 decarboxylase, pyridoxal-dependent YP_001182073.1 PFAM: protein of unknown function DUF465; KEGG: son:SO4134 hypothetical protein YP_001182074.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_001182075.1 KEGG: shm:Shewmr7_0448 hypothetical protein YP_001182076.1 PFAM: protein of unknown function DUF107; KEGG: shm:Shewmr7_0449 protein of unknown function DUF107 YP_001182077.1 PFAM: band 7 protein; KEGG: son:SO4129 SPFH domain/Band 7 family protein YP_001182078.1 PFAM: band 7 protein; KEGG: son:SO4128 SPFH domain/Band 7 family protein YP_001182079.1 KEGG: son:SO4126 hypothetical protein YP_001182080.1 PFAM: Sporulation domain protein; KEGG: son:SO4124 cell division protein FtsN, putative YP_001182081.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001182082.1 KEGG: she:Shewmr4_3495 primosomal protein N'; TIGRFAM: primosomal protein N'; PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001182083.1 KEGG: son:SO4121 hypothetical protein YP_001182084.2 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001182085.1 PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: shm:Shewmr7_0460 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) YP_001182086.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_001182087.1 KEGG: son:SO4114.2 hypothetical biogenesis protein MshI YP_001182088.1 KEGG: shm:Shewmr7_0463 hypothetical protein YP_001182089.1 KEGG: shm:Shewmr7_0464 MSHA biogenesis protein MshJ YP_001182090.1 KEGG: shm:Shewmr7_0465 MSHA biogenesis protein MshK YP_001182091.1 TIGRFAM: pilus (MSHA type) biogenesis protein MshL; PFAM: type II and III secretion system protein; Secretin domain protein; Secretin/TonB, short N-terminal domain; KEGG: she:Shewmr4_3486 pilus (MSHA type) biogenesis protein MshL YP_001182092.1 KEGG: she:Shewmr4_3485 MSHA biogenesis protein MshM YP_001182093.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: son:SO4110 MSHA biogenesis protein MshN, putative YP_001182094.1 PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; KEGG: shm:Shewmr7_0469 type II secretion system protein E YP_001182095.1 PFAM: type II secretion system protein; KEGG: son:SO4108 MSHA biogenesis protein MshG YP_001182096.1 KEGG: son:SO4107 hypothetical protein YP_001182097.1 KEGG: son:SO4106 MSHA pilin protein MshB YP_001182098.1 KEGG: she:Shewmr4_3479 methylation site containing protein YP_001182099.1 KEGG: she:Shewmr4_3478 methylation site containing protein YP_001182100.1 KEGG: son:SO4104 MSHA pilin protein MshC YP_001182101.1 KEGG: shm:Shewmr7_0475 methylation site containing protein YP_001182102.1 KEGG: son:SO4102 MSHA biogenesis protein MshO YP_001182103.1 KEGG: shm:Shewmr7_0477 MSHA biogenesis protein MshP YP_001182104.1 KEGG: shm:Shewmr7_0478 MSHA biogenesis protein MshQ YP_001182105.1 functions in MreBCD complex in some organisms YP_001182106.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001182107.1 PFAM: Rod shape-determining protein MreD; KEGG: son:SO4096 rod shape-determining protein MreD YP_001182108.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: shm:Shewmr7_0482 maf protein YP_001182109.1 involved in the processing of the 5'end of 16S rRNA YP_001182110.1 KEGG: she:Shewmr4_3467 hypothetical protein YP_001182111.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: son:SO4092 hydrolase, carbon-nitrogen family YP_001182112.1 PFAM: peptidase U62, modulator of DNA gyrase; KEGG: son:SO4091 TldD protein YP_001182113.1 PFAM: outer membrane efflux protein; KEGG: shm:Shewmr7_0487 outer membrane efflux protein YP_001182114.1 PFAM: secretion protein HlyD family protein; KEGG: son:SO4089 HlyD family secretion protein YP_001182115.1 PFAM: ABC-2 type transporter; KEGG: son:SO4088 conserved hypothetical protein YP_001182116.1 PFAM: ABC-2 type transporter; KEGG: she:Shewmr4_3461 ABC-2 type transporter YP_001182117.1 PFAM: Ion transport protein; KEGG: sde:Sde_1761 cold shock protein YP_001182118.1 PFAM: amino acid permease-associated region; KEGG: she:Shewmr4_3458 amino acid permease-associated region YP_001182119.1 KEGG: pfo:Pfl_3517 hypothetical protein YP_001182120.1 KEGG: bam:Bamb_5633 hypothetical protein YP_001182121.1 PFAM: Catalase domain protein; KEGG: nmu:Nmul_A1515 catalase YP_001182122.1 PFAM: MgtC/SapB transporter; KEGG: pcr:Pcryo_2508 MgtC/SapB transporter YP_001182123.1 PFAM: Ig domain protein, group 1 domain protein; KEGG: shm:Shewmr7_0493 Ig domain protein, group 1 domain protein YP_001182124.1 PFAM: protein of unknown function DUF615; KEGG: shm:Shewmr7_0494 protein of unknown function DUF615 YP_001182125.1 PFAM: peptidase U62, modulator of DNA gyrase; KEGG: she:Shewmr4_3455 peptidase U62, modulator of DNA gyrase YP_001182126.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO4077 TonB-dependent receptor, putative YP_001182127.1 KEGG: shm:Shewmr7_0497 hypothetical protein YP_001182128.1 PFAM: protein of unknown function DUF331; KEGG: shm:Shewmr7_0498 protein of unknown function DUF331 YP_001182129.1 TIGRFAM: fumarate hydratase, class II; PFAM: fumarate lyase; KEGG: chu:CHU_3664 fumarate hydratase/aspartate ammonia-lyase YP_001182130.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_001182131.1 PFAM: protein of unknown function DUF541; KEGG: shm:Shewmr7_0500 protein of unknown function DUF541 YP_001182132.1 PFAM: EAL domain protein; KEGG: ilo:IL0500 Signalling protein containing EAL domain YP_001182133.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_0501 methyltransferase type 11 YP_001182134.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_3717 TonB-dependent siderophore receptor YP_001182135.1 PFAM: OmpA domain protein transmembrane region-containing protein; KEGG: sfr:Sfri_0734 OmpA domain protein transmembrane region-containing protein YP_001182136.1 PFAM: MORN variant repeat protein; KEGG: fnu:FN2119 hypothetical exported 24-amino acid repeat protein YP_001182137.1 PFAM: protein of unknown function DUF1568; KEGG: son:SO1241 hypothetical protein YP_001182138.1 PFAM: transposase Tn5, dimerisation domain protein; KEGG: plu:plu4494 transposase, IS4 family YP_001182139.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001182140.1 KEGG: shm:Shewmr7_0505 hypothetical protein YP_001182141.1 KEGG: she:Shewmr4_3445 pentapeptide repeat protein YP_001182142.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4061 polysulfide reductase, subunit B YP_001182143.1 PFAM: Polysulphide reductase, NrfD; KEGG: son:SO4060 polysulfide reductase, subunit C YP_001182144.1 PFAM: protein of unknown function DUF81; KEGG: son:SO4058 hypothetical protein YP_001182145.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_001182146.1 KEGG: son:SO4056 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_001182147.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001182148.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_001182149.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: son:SO4053 methyl-accepting chemotaxis protein YP_001182150.1 PFAM: regulatory protein, MarR; KEGG: she:Shewmr4_3435 transcriptional regulator, MarR family YP_001182151.1 PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_0517 secretion protein HlyD family protein YP_001182152.1 KEGG: she:Shewmr4_3433 hypothetical protein YP_001182153.1 KEGG: shm:Shewmr7_0519 cytochrome c family protein YP_001182154.1 PFAM: cytochrome c, class I; KEGG: son:SO4047 cytochrome c family protein YP_001182155.1 KEGG: son:SO1428 outer membrane protein YP_001182156.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: son:SO1429 anaerobic dimethyl sulfoxide reductase, A subunit YP_001182157.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO1430 anaerobic dimethyl sulfoxide reductase, B subunit YP_001182158.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: son:SO1431 hypothetical protein YP_001182159.1 KEGG: son:SO1432 hypothetical protein YP_001182160.1 KEGG: son:SO4044 hypothetical protein YP_001182161.1 TIGRFAM: TonB family protein; KEGG: son:SO4043 TonB domain protein YP_001182162.1 KEGG: son:SO4042 hydratase/decarboxylase family protein YP_001182163.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: son:SO4040 integral membrane domain protein YP_001182164.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO4039 hydrolase, haloacid dehalogenase-like family YP_001182165.1 KEGG: she:Shewmr4_3425 hypothetical protein YP_001182166.1 PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO4034 ATP-dependent RNA helicase DeaD YP_001182167.1 TIGRFAM: excinuclease ABC, A subunit; PFAM: ABC transporter related; KEGG: son:SO4030 excinuclease ABC, A subunit YP_001182168.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO4029 transporter, putative YP_001182169.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: son:SO4028 single-strand binding protein YP_001182170.1 TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: she:Shewmr4_0607 glutamine amidotransferase of anthranilate synthase YP_001182171.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9B, dipeptidylpeptidase IV domain protein; KEGG: shm:Shewmr7_3422 peptidase S9, prolyl oligopeptidase active site domain protein YP_001182172.1 PFAM: HDOD; KEGG: she:Shewmr4_0609 putative signal transduction protein YP_001182173.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: shm:Shewmr7_3420 alpha/beta hydrolase fold-3 domain protein YP_001182174.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_001182175.1 PFAM: arginine N-succinyltransferase beta subunit; KEGG: shm:Shewmr7_3418 arginine N-succinyltransferase YP_001182176.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_001182177.1 KEGG: she:Shewmr4_0614 hypothetical protein YP_001182178.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: shm:Shewmr7_3415 periplasmic sensor signal transduction histidine kinase YP_001182179.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3414 two component transcriptional regulator, winged helix family YP_001182180.1 KEGG: shm:Shewmr7_3413 hypothetical protein YP_001182181.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_001182182.1 KEGG: son:SO0625 hypothetical protein YP_001182183.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: son:SO0628 GGDEF domain protein YP_001182184.1 KEGG: shm:Shewmr7_3407 ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; Helicase ATP-dependent, C-terminal domain protein; SMART: DEAD-like helicases-like YP_001182185.1 KEGG: she:Shewmr4_0624 penicillin-binding protein 1B; TIGRFAM: penicillin-binding protein 1B; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_001182186.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: son:SO0635 peptidyl-prolyl cis-trans isomerase C YP_001182187.1 KEGG: shm:Shewmr7_3401 hypothetical protein YP_001182188.1 KEGG: son:SO4012 hypothetical protein YP_001182189.1 KEGG: son:SO4011 hypothetical protein YP_001182190.1 KEGG: she:Shewmr4_0632 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001182191.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: she:Shewmr4_0633 molydopterin dinucleotide-binding region YP_001182192.1 PFAM: Polysulphide reductase, NrfD; KEGG: she:Shewmr4_0634 polysulphide reductase, NrfD YP_001182193.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: she:Shewmr4_0635 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001182194.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_0636 periplasmic sensor signal transduction histidine kinase YP_001182195.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: she:Shewmr4_0637 two component transcriptional regulator, LuxR family YP_001182196.1 KEGG: she:Shewmr4_0638 hypothetical protein YP_001182197.1 KEGG: shm:Shewmr7_3381 hypothetical protein YP_001182198.1 KEGG: shm:Shewmr7_3380 hypothetical protein YP_001182199.1 KEGG: son:SO4005 hypothetical protein YP_001182200.1 PFAM: sodium:dicarboxylate symporter; KEGG: she:Shewmr4_0642 sodium:dicarboxylate symporter YP_001182201.1 PFAM: chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: pha:PSHAa2387 chemotaxis sensory protein YP_001182202.1 PFAM: Uncharacterized protein UPF0114; KEGG: son:SO3997 hypothetical protein YP_001182203.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria; KEGG: nmu:Nmul_A1193 transport-associated YP_001182204.1 PFAM: NERD domain protein; KEGG: she:Shewmr4_0648 NERD domain protein YP_001182205.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001182206.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9B, dipeptidylpeptidase IV domain protein; KEGG: shm:Shewmr7_3372 peptidase S9B, dipeptidylpeptidase IV domain protein YP_001182207.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3371 two component transcriptional regulator, winged helix family YP_001182208.1 KEGG: son:SO3987 hypothetical protein YP_001182209.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_001182210.1 PFAM: Mg2+ transporter protein, CorA family protein; KEGG: shm:Shewmr7_3367 Mg2 transporter protein, CorA family protein YP_001182211.1 PFAM: Uncharacterized conserved protein UCP006287; KEGG: she:Shewmr4_0656 uncharacterized conserved protein UCP006287 YP_001182212.1 PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: shm:Shewmr7_3365 two component transcriptional regulator, LuxR family YP_001182213.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase, dimerisation and phosphoacceptor region; KEGG: shm:Shewmr7_3364 signal transduction histidine kinase, nitrate/nitrite-specific, NarQ YP_001182214.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_001182215.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: she:Shewmr4_3377 ABC transporter related YP_001182216.1 PFAM: protein of unknown function DUF134; Sigma-70, region 4 type 2; KEGG: son:SO0727 hypothetical protein YP_001182217.1 KEGG: son:SO0728 hypothetical protein YP_001182218.1 KEGG: she:Shewmr4_3375 thioredoxin domain YP_001182219.1 PFAM: transcriptional regulator PadR family protein; KEGG: son:SO0734 hypothetical protein YP_001182220.1 KEGG: son:SO0735 hypothetical protein YP_001182221.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO0737 TonB-dependent receptor, putative YP_001182222.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: shm:Shewmr7_0586 transcriptional regulator, AraC family YP_001182223.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: she:Shewmr4_3366 lysine exporter protein (LysE/YggA) YP_001182224.1 KEGG: son:SO0764 hypothetical protein YP_001182225.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_0550 acriflavin resistance protein YP_001182226.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_0551 efflux transporter, RND family, MFP subunit YP_001182227.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0701 transcriptional regulator, LysR family YP_001182228.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO0702 MATE efflux family protein YP_001182229.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001182230.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001182233.1 PFAM: protein of unknown function DUF88; KEGG: sfr:Sfri_3658 protein of unknown function DUF88 YP_001182234.1 KEGG: shm:Shewmr7_3360 hypothetical protein YP_001182235.1 PFAM: protein of unknown function RIO1; KEGG: shm:Shewmr7_3358 protein of unknown function RIO1 YP_001182236.1 PFAM: transposase IS3/IS911 family protein; KEGG: shm:Shewmr7_3357 transposase IS3/IS911 family protein YP_001182237.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen; KEGG: she:Shewmr4_0666 OmpA/MotB domain protein YP_001182238.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; KEGG: she:Shewmr4_0667 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_001182239.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: son:SO3966 magnesium transporter YP_001182240.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: she:Shewmr4_0669 phosphocarrier, HPr family YP_001182241.1 PFAM: Uncharacterized P-loop ATPase protein UPF0042; KEGG: shm:Shewmr7_3352 uncharacterized P-loop ATPase protein UPF0042 YP_001182242.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: shm:Shewmr7_3351 PTS IIA-like nitrogen-regulatory protein PtsN YP_001182243.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: shm:Shewmr7_3350 sigma 54 modulation protein/ribosomal protein S30EA YP_001182244.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001182245.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_3348 ABC transporter related YP_001182246.1 PFAM: OstA family protein; KEGG: shm:Shewmr7_3347 OstA family protein YP_001182247.1 PFAM: protein of unknown function DUF1239; KEGG: son:SO3958 hypothetical protein YP_001182248.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_001182249.1 KEGG: shm:Shewmr7_3344 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_001182250.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_3343 ABC transporter related YP_001182251.1 PFAM: protein of unknown function DUF140; KEGG: son:SO3953 putative membrane protein YP_001182252.1 PFAM: Mammalian cell entry related domain protein; KEGG: son:SO3952 mce-related protein YP_001182253.1 PFAM: toluene tolerance family protein; KEGG: shm:Shewmr7_3340 toluene tolerance family protein YP_001182254.1 KEGG: son:SO3950 SpoIIAA family protein YP_001182255.1 PFAM: BolA family protein; KEGG: shm:Shewmr7_3338 BolA family protein YP_001182256.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001182257.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: ilo:IL0163 2OG-Fe(II) oxygenase superfamily protein YP_001182258.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: dge:Dgeo_0011 methionine gamma-lyase YP_001182259.1 KEGG: son:SO4655 sulfate ABC transporter, ATP-binding protein; TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001182260.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysW; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO4654 sulfate ABC transporter, permease protein YP_001182261.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO4653 sulfate ABC transporter, permease protein YP_001182262.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein, family 1; KEGG: son:SO4652 sulfate ABC transporter, periplasmic sulfate-binding protein YP_001182263.1 KEGG: son:SO4651 hypothetical protein YP_001182264.1 PFAM: protein of unknown function DUF1234; KEGG: son:SO4650 hypothetical protein YP_001182266.1 PFAM: Radical SAM domain protein; KEGG: vpa:VPA0442 hypothetical protein YP_001182267.1 PFAM: Integrase, catalytic region; KEGG: vch:VCA0791 transposase OrfAB, subunit B YP_001182268.1 PFAM: transposase IS3/IS911 family protein; KEGG: vch:VCA0792 transposase OrfAB, subunit A YP_001182269.1 PFAM: Radical SAM domain protein; KEGG: vpa:VPA0443 hypothetical protein YP_001182270.1 TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: son:SO3943 protease DegS YP_001182271.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: she:Shewmr4_3271 protease Do YP_001182272.1 PFAM: AFG1-family ATPase; KEGG: she:Shewmr4_3270 AFG1-family ATPase YP_001182273.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001182274.1 forms a direct contact with the tRNA during translation YP_001182275.1 KEGG: shm:Shewmr7_0680 hypothetical protein YP_001182276.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001182277.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: shm:Shewmr7_0682 Sel1 domain protein repeat-containing protein YP_001182278.1 KEGG: shm:Shewmr7_0683 ribonuclease R; TIGRFAM: VacB and RNase II family 3'-5' exoribonucleases; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; Ribonuclease B, OB region N-terminal domain; Ribonuclease R winged-helix domain protein; SMART: Cold shock protein YP_001182279.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_001182280.1 PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_3262 major facilitator superfamily MFS_1 YP_001182281.1 PFAM: protein of unknown function DUF481; KEGG: she:Shewmr4_3261 protein of unknown function DUF481 YP_001182282.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001182283.1 binds single-stranded DNA at the primosome assembly site YP_001182284.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001182285.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001182286.1 KEGG: shm:Shewmr7_0691 hypothetical protein YP_001182287.1 KEGG: son:SO3917 replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase, N-terminal domain protein; DnaB domain protein helicase, C-terminal domain protein; SMART: AAA ATPase YP_001182288.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001182289.1 KEGG: shm:Shewmr7_0696 putative chemotaxis protein CheX YP_001182290.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase, DuS; KEGG: she:Shewmr4_3243 TIM-barrel protein, YjbN family YP_001182291.1 KEGG: shm:Shewmr7_0747 hypothetical protein YP_001182292.1 KEGG: she:Shewmr4_3241 phage shock protein C, PspC YP_001182293.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: shm:Shewmr7_0749 enoyl-CoA hydratase/isomerase YP_001182294.1 PFAM: protein of unknown function DUF461; KEGG: son:SO3907 hypothetical protein YP_001182295.1 KEGG: shm:Shewmr7_0751 hypothetical protein YP_001182296.1 KEGG: she:Shewmr4_3237 hypothetical protein YP_001182297.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_001182298.1 PFAM: NUDIX hydrolase; KEGG: son:SO3903 ADP-ribose pyrophosphatase YP_001182299.1 PFAM: protein of unknown function DUF1249; KEGG: son:SO3902 hypothetical protein YP_001182300.1 PFAM: metallophosphoesterase; Calcineurin phosphoesterase C-terminal domain protein; KEGG: she:Shewmr4_3233 calcineurin phosphoesterase C-terminal domain protein YP_001182301.1 PFAM: protein of unknown function UPF0227; KEGG: she:Shewmr4_3232 protein of unknown function UPF0227 YP_001182302.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001182303.1 KEGG: shm:Shewmr7_0759 L-sorbosone dehydrogenase, putative YP_001182304.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001182305.1 TIGRFAM: hemerythrin-like metal-binding protein; PFAM: chemotaxis sensory transducer; Hemerythrin HHE cation binding domain protein; KEGG: son:SO3890 methyl-accepting chemotaxis protein YP_001182306.1 KEGG: sfr:Sfri_0507 hypothetical protein YP_001182307.1 KEGG: she:Shewmr4_3224 hypothetical protein YP_001182308.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO3894 sensor histidine kinase YP_001182309.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: she:Shewmr4_3226 UBA/ThiF-type NAD/FAD binding protein YP_001182310.1 PFAM: porin, Gram-negative type; KEGG: shm:Shewmr7_0761 porin, gram-negative type YP_001182311.1 TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: shm:Shewmr7_0771 putative iron-sulfur cluster binding protein YP_001182312.1 KEGG: son:SO3856 hypothetical protein YP_001182313.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_001182314.1 PFAM: protein of unknown function DUF1456; KEGG: shm:Shewmr7_0779 protein of unknown function DUF1456 YP_001182315.1 KEGG: she:Shewmr4_3186 putative manganese transporter YP_001182316.1 PFAM: membrane-flanked domain; KEGG: son:SO3849 hypothetical protein YP_001182317.1 KEGG: shm:Shewmr7_0784 hypothetical protein YP_001182318.1 KEGG: she:Shewmr4_3181 hypothetical protein YP_001182319.1 KEGG: she:Shewmr4_3180 hypothetical protein YP_001182320.1 PFAM: peptidase M13, neprilysin; peptidase M13; KEGG: she:Shewmr4_3179 endothelin-converting enzyme 1 YP_001182321.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: shm:Shewmr7_0788 pseudouridine synthase, Rsu YP_001182322.1 KEGG: she:Shewmr4_3177 hypothetical protein YP_001182323.1 KEGG: she:Shewmr4_3176 hypothetical protein YP_001182324.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: son:SO3840 RNA polymerase sigma-70 factor, ECF subfamily YP_001182325.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_0792 methyl-accepting chemotaxis sensory transducer YP_001182326.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001182327.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001182328.1 PFAM: outer membrane lipoprotein LolB; KEGG: son:SO3835 outer membrane lipoprotein LolB YP_001182329.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001182330.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001182331.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: she:Shewmr4_3168 modification methylase, HemK family YP_001182332.1 KEGG: cgb:cg1190 hypothetical protein YP_001182334.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_0799 GCN5-related N-acetyltransferase YP_001182335.1 PFAM: Invasion gene expression up-regulator, SirB; KEGG: shm:Shewmr7_0800 invasion gene expression up-regulator, SirB YP_001182336.1 KEGG: shm:Shewmr7_0801 hypothetical protein YP_001182337.1 PFAM: protein of unknown function DUF819; KEGG: shm:Shewmr7_0802 protein of unknown function DUF819 YP_001182338.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001182339.1 TIGRFAM: flavocytochrome c; PFAM: glucose-inhibited division protein A; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sfr:Sfri_2586 flavocytochrome c YP_001182340.1 KEGG: she:Shewmr4_3227 outer membrane porin, putative YP_001182341.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sfr:Sfri_2588 transcriptional regulator, LysR family protein YP_001182342.1 PFAM: protein of unknown function DUF819; KEGG: sfr:Sfri_2589 protein of unknown function DUF819 YP_001182343.1 PFAM: EAL domain protein; KEGG: son:SO3821 rtn protein YP_001182344.1 PFAM: nitrogen regulatory protein P-II; KEGG: shm:Shewmr7_0808 nitrogen regulatory protein P-II YP_001182345.1 KEGG: she:Shewmr4_3158 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein YP_001182346.1 PFAM: VanZ family protein; KEGG: she:Shewmr4_3157 VanZ family protein YP_001182347.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001182348.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO3814 AmpG protein, putative YP_001182349.1 KEGG: shm:Shewmr7_0813 hypothetical protein YP_001182350.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: shm:Shewmr7_0814 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001182351.1 PFAM: Uncharacterized lipoprotein; KEGG: shm:Shewmr7_0815 uncharacterized lipoprotein YP_001182352.1 PFAM: OmpA domain protein transmembrane region-containing protein; KEGG: son:SO3810 OmpA-like transmembrane domain protein YP_001182353.1 KEGG: she:Shewmr4_3150 hypothetical protein YP_001182354.1 KEGG: shm:Shewmr7_0818 sterol desaturase family protein YP_001182355.1 KEGG: she:Shewmr4_3148 hypothetical protein YP_001182356.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: shm:Shewmr7_0820 UDP-N-acetylmuramate YP_001182357.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; KEGG: shm:Shewmr7_0821 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001182358.1 KEGG: shm:Shewmr7_0822 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_001182359.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO3802 ABC transporter, ATP-binding protein YP_001182360.1 PFAM: ABC-2 type transporter; KEGG: she:Shewmr4_3143 ABC-2 type transporter YP_001182361.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; KEGG: son:SO1915 serine protease, subtilase family YP_001182362.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_001182363.1 PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_0827 pseudouridylate synthase YP_001182364.1 PFAM: peptidase U32; KEGG: shm:Shewmr7_0828 peptidase U32 YP_001182365.1 KEGG: shm:Shewmr7_0831 hypothetical protein YP_001182366.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: shm:Shewmr7_0832 cupin 2, conserved barrel domain protein YP_001182367.1 PFAM: peptidase M19, renal dipeptidase; KEGG: shm:Shewmr7_0834 twin-arginine translocation pathway signal YP_001182368.1 PFAM: Fe-S metabolism associated SufE; KEGG: she:Shewmr4_3132 Fe-S metabolism associated SufE YP_001182369.1 TIGRFAM: cysteine desulfurases, SufS subfamily; PFAM: aminotransferase, class V; aminotransferase, class I and II; KEGG: son:SO3789 aminotransferase, class V YP_001182370.1 PFAM: MltA-interacting MipA family protein; KEGG: sfr:Sfri_3064 MltA-interacting MipA family protein YP_001182371.1 KEGG: sfr:Sfri_3063 hypothetical protein YP_001182372.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sdn:Sden_0557 response regulator receiver YP_001182373.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: sdn:Sden_0558 ATP-binding region, ATPase-like protein YP_001182374.1 KEGG: sfr:Sfri_3059 hypothetical protein YP_001182375.1 PFAM: MltA-interacting MipA family protein; KEGG: sfr:Sfri_3058 MltA-interacting MipA family protein YP_001182376.1 PFAM: aldo/keto reductase; KEGG: shm:Shewmr7_3273 aldo/keto reductase YP_001182377.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001182378.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001182379.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001182380.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_001182381.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_001182382.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001182383.1 PFAM: Ankyrin; KEGG: son:SO0908 hypothetical protein YP_001182384.1 PFAM: beta-lactamase; KEGG: son:SO0914 hypothetical protein YP_001182386.1 PFAM: GCN5-related N-acetyltransferase; regulatory protein, MarR; KEGG: shm:Shewmr7_3265 transcriptional regulator, MarR family with acetyltransferase activity YP_001182387.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_001182388.1 PFAM: peptidase S45, penicillin amidase; KEGG: shm:Shewmr7_3263 peptidase S45, penicillin amidase YP_001182389.1 PFAM: aromatic amino acid permease; KEGG: son:SO0919 serine transporter, putative YP_001182390.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_3261 GCN5-related N-acetyltransferase YP_001182391.1 PFAM: sodium:dicarboxylate symporter; KEGG: shm:Shewmr7_3259 sodium:dicarboxylate symporter YP_001182392.1 PFAM: protein of unknown function DUF306, Meta and HslJ; KEGG: shm:Shewmr7_3258 protein of unknown function DUF306, MetA and HslJ YP_001182393.1 KEGG: she:Shewmr4_0766 hypothetical protein YP_001182394.1 KEGG: shm:Shewmr7_3255 acetyltransferase, GNAT family YP_001182395.1 KEGG: shm:Shewmr7_3253 hypothetical protein YP_001182396.1 PFAM: protein of unknown function DUF1568; KEGG: shm:Shewmr7_1178 protein of unknown function DUF1568 YP_001182397.1 KEGG: bfr:BF2853 hypothetical protein YP_001182398.1 KEGG: shm:Shewmr7_3252 hypothetical protein YP_001182399.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001182400.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001182401.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_001182402.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001182403.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_001182404.1 PFAM: protein of unknown function DUF481; KEGG: shm:Shewmr7_3246 protein of unknown function DUF481 YP_001182405.1 KEGG: she:Shewmr4_0778 Na+/H+ antiporter YP_001182406.1 KEGG: she:Shewmr4_0781 hypothetical protein YP_001182407.1 KEGG: shm:Shewmr7_3241 cytochrome c, putative YP_001182408.1 PFAM: transcriptional regulator domain protein; KEGG: son:SO0940 transcriptional regulator-related protein YP_001182409.1 KEGG: she:Shewmr4_0784 hypothetical protein YP_001182410.1 KEGG: shm:Shewmr7_3238 hypothetical protein YP_001182411.1 KEGG: she:Shewmr4_0786 putative PAS/PAC sensor protein YP_001182412.1 PFAM: Radical SAM domain protein; KEGG: son:SO0944 hypothetical protein YP_001182413.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_3235 acriflavin resistance protein YP_001182414.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_3234 efflux transporter, RND family, MFP subunit YP_001182415.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_001182416.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: she:Shewmr4_0793 methyltransferase small YP_001182417.1 PFAM: branched-chain amino acid transport system II carrier protein; KEGG: she:Shewmr4_0794 branched-chain amino acid transport system II carrier protein YP_001182418.1 TIGRFAM: tyrosine recombinase XerD; PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: shm:Shewmr7_3228 tyrosine recombinase XerD YP_001182419.1 KEGG: shm:Shewmr7_3227 thiol:disulfide interchange protein DsbC YP_001182420.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: shm:Shewmr7_3226 single-stranded-DNA-specific exonuclease RecJ YP_001182421.1 KEGG: son:SO0953 hypothetical protein YP_001182422.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_0799 GCN5-related N-acetyltransferase YP_001182423.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glutaredoxin; KEGG: she:Shewmr4_0800 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001182424.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: son:SO0958 alkyl hydroperoxide reductase, C subunit YP_001182425.1 PFAM: peptidase M17, leucyl aminopeptidase domain protein; KEGG: shm:Shewmr7_3221 leucyl aminopeptidase YP_001182426.1 PFAM: Spermine synthase; KEGG: shm:Shewmr7_3220 spermine synthase YP_001182427.1 KEGG: shm:Shewmr7_3219 hypothetical protein YP_001182428.1 KEGG: psb:Psyr_4989 hypothetical protein YP_001182431.1 PFAM: dienelactone hydrolase; KEGG: she:Shewmr4_0806 dienelactone hydrolase YP_001182432.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: shm:Shewmr7_3216 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein YP_001182433.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO0970 fumarate reductase flavoprotein subunit precursor YP_001182434.1 KEGG: she:Shewmr4_0809 hypothetical protein YP_001182435.1 PFAM: Methyltransferase type 12; KEGG: son:SO0972 hypothetical protein YP_001182436.1 KEGG: son:SO0973 hypothetical protein YP_001182437.1 PFAM: Rhomboid family protein; KEGG: son:SO1000 rhomboid family protein YP_001182438.1 PFAM: sodium/calcium exchanger membrane region; KEGG: son:SO1001 calcium/proton antiporter YP_001182440.1 KEGG: son:SO1003 hypothetical protein YP_001182441.1 KEGG: son:SO1004 hypothetical protein YP_001182442.1 PFAM: protein of unknown function UPF0016; KEGG: she:Shewmr4_3028 protein of unknown function UPF0016 YP_001182444.1 PFAM: aromatic amino acid permease; Amino acid transporter, transmembrane; KEGG: shm:Shewmr7_0948 aromatic amino acid permease YP_001182445.1 KEGG: shm:Shewmr7_0949 hypothetical protein YP_001182446.1 KEGG: son:SO4411 hypothetical protein YP_001182447.1 KEGG: son:SOA0150 hypothetical protein YP_001182449.1 KEGG: son:SO0729 hypothetical protein YP_001182450.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: shm:Shewmr7_0952 pseudouridine synthase, Rsu YP_001182451.1 KEGG: she:Shewmr4_0918 hypothetical protein YP_001182452.1 PFAM: Na+/H+ antiporter NhaC; KEGG: shm:Shewmr7_0954 Na+/H+ antiporter NhaC YP_001182453.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_0924 methyl-accepting chemotaxis sensory transducer YP_001182454.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: son:SO1091 hypothetical protein YP_001182455.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: shm:Shewmr7_0961 transcriptional regulator, AraC family YP_001182456.1 KEGG: son:SO1094 hypothetical transcription elongation factor YP_001182457.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II; KEGG: shm:Shewmr7_0963 cytochrome d ubiquinol oxidase, subunit II YP_001182458.1 PFAM: cytochrome bd ubiquinol oxidase, subunit I; KEGG: shm:Shewmr7_0964 cytochrome bd ubiquinol oxidase, subunit I YP_001182459.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: shm:Shewmr7_0965 transcriptional regulator, GntR family YP_001182460.1 KEGG: shm:Shewmr7_0966 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_001182461.1 KEGG: son:SO1096 hypothetical protein YP_001182462.1 PFAM: methyltransferase small; Methyltransferase type 12; KEGG: son:SO1097 putative ribosomal RNA small subunit methyltransferase D YP_001182463.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: shm:Shewmr7_0969 2OG-Fe(II) oxygenase YP_001182464.1 PFAM: BolA family protein; KEGG: shm:Shewmr7_0970 BolA family protein YP_001182465.1 PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: shm:Shewmr7_0971 TRAP dicarboxylate transporter-DctP subunit YP_001182466.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_001182467.1 PFAM: TonB-dependent receptor; KEGG: she:Shewmr4_0935 TonB-dependent receptor YP_001182468.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001182469.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001182470.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001182471.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_001182472.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_001182473.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001182474.1 PFAM: ApbE family lipoprotein; KEGG: she:Shewmr4_0942 ApbE family lipoprotein YP_001182475.1 PFAM: protein of unknown function DUF539; KEGG: shm:Shewmr7_0981 protein of unknown function DUF539 YP_001182476.1 TIGRFAM: bacterioferritin; PFAM: Ferritin, Dps family protein; KEGG: shm:Shewmr7_0982 bacterioferritin YP_001182477.1 TIGRFAM: bacterioferritin; PFAM: Ferritin, Dps family protein; KEGG: son:SO1112 bacterioferritin subunit 1 YP_001182478.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_0946 methyl-accepting chemotaxis sensory transducer YP_001182479.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001182480.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: ilo:IL2190 transcriptional regulator, LysR family YP_001182481.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: ilo:IL2191 predicted permease, DMT superfamily YP_001182482.1 KEGG: she:Shewmr4_0948 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001182483.1 PFAM: peptidase M17, leucyl aminopeptidase domain protein; KEGG: shm:Shewmr7_0987 peptidase M17, leucyl aminopeptidase domain protein YP_001182484.1 KEGG: sfr:Sfri_0964 hypothetical protein YP_001182485.1 PFAM: protein of unknown function DUF1568; KEGG: son:SO1890 hypothetical protein YP_001182486.1 KEGG: sdn:Sden_1152 hypothetical protein YP_001182487.1 KEGG: son:SO3676 hypothetical protein YP_001182488.1 with HmuTU is involved in the transport of hemin YP_001182489.1 PFAM: transport system permease protein; KEGG: son:SO3674 hemin ABC transporter, permease protein YP_001182490.1 PFAM: periplasmic binding protein; KEGG: son:SO3673 hemin ABC transporter, periplasmic hemin-binding protein YP_001182491.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: son:SO3672 TonB system transport protein ExbD1 YP_001182492.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: son:SO3671 TonB system transport protein ExbB1 YP_001182493.1 TIGRFAM: TonB family protein; KEGG: son:SO3670 TonB1 protein YP_001182494.1 TIGRFAM: TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO3669 heme transport protein YP_001182495.1 PFAM: protein of unknown function DUF1008; KEGG: son:SO3668 hypothetical protein YP_001182496.1 PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding; KEGG: son:SO3667 hypothetical protein YP_001182497.1 KEGG: she:Shewmr4_0882 lipid A ABC exporter family, fused ATPase and inner membrane subunits; TIGRFAM: lipid A ABC exporter family, fused ATPase and inner membrane subunits; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001182498.1 PFAM: AMP-dependent synthetase and ligase; KEGG: shm:Shewmr7_3139 AMP-dependent synthetase and ligase YP_001182499.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_3136 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001182500.1 KEGG: she:Shewmr4_0887 transcriptional regulator, fis family; TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; AAA ATPase YP_001182501.1 KEGG: she:Shewmr4_0888 thiol:disulfide interchange protein, putative YP_001182502.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shm:Shewmr7_3132 lysine exporter protein (LysE/YggA) YP_001182503.1 KEGG: son:SO3656 hypothetical protein YP_001182504.1 KEGG: son:SO3655 pilin, putative YP_001182505.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001182506.1 PFAM: Polyprenyl synthetase; KEGG: shm:Shewmr7_3126 trans-hexaprenyltranstransferase YP_001182507.1 PFAM: ribosomal protein L21; KEGG: sdn:Sden_2927 ribosomal protein L21 YP_001182508.1 involved in the peptidyltransferase reaction during translation YP_001182509.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001182510.1 PFAM: protein of unknown function DUF1212; KEGG: she:Shewmr4_0898 protein of unknown function DUF1212 YP_001182511.1 KEGG: son:SO3647 hypothetical protein YP_001182512.1 PFAM: dihydrofolate reductase region; KEGG: shm:Shewmr7_3120 dihydrofolate reductase YP_001182513.1 KEGG: son:SO3645 hypothetical protein YP_001182514.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_0902 methyl-accepting chemotaxis sensory transducer YP_001182515.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_001182516.1 protein associated with Co2+ and Mg2+ efflux YP_001182517.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001182518.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001182519.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: she:Shewmr4_0907 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001182520.1 PFAM: OstA family protein; Organic solvent tolerance protein; KEGG: shm:Shewmr7_3112 organic solvent tolerance protein YP_001182521.1 PFAM: aminoglycoside phosphotransferase; KEGG: she:Shewmr4_0909 aminoglycoside phosphotransferase YP_001182522.1 PFAM: Nucleotidyl transferase; KEGG: son:SO3634 nucleotidyltransferase family protein YP_001182523.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_001182524.1 KEGG: shm:Shewmr7_3108 hypothetical protein YP_001182525.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: shm:Shewmr7_3107 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein YP_001182526.1 PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_3103 tetratricopeptide TPR_2 repeat protein YP_001182527.1 KEGG: she:Shewmr4_3021 hypothetical protein YP_001182528.1 PFAM: pseudouridine synthase; KEGG: sdn:Sden_0688 pseudouridine synthase YP_001182529.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001182530.1 KEGG: son:SO3602 sulfate ABC transporter, ATP-binding protein; TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001182531.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysW; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO3601 sulfate ABC transporter, permease protein YP_001182532.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO3600 sulfate ABC transporter, permease protein YP_001182533.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein, family 1; KEGG: she:Shewmr4_3012 sulfate ABC transporter, periplasmic sulfate-binding protein YP_001182534.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_001182535.1 KEGG: she:Shewmr4_3009 hypothetical protein YP_001182536.1 PFAM: protein of unknown function DUF1289; KEGG: shm:Shewmr7_3089 protein of unknown function DUF1289 YP_001182537.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_3007 periplasmic sensor signal transduction histidine kinase YP_001182538.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3087 two component transcriptional regulator, winged helix family YP_001182539.1 KEGG: shm:Shewmr7_3086 hypothetical protein YP_001182540.1 PFAM: MltA-interacting MipA family protein; KEGG: son:SO3592 putative outer membrane protein YP_001182541.1 KEGG: shm:Shewmr7_3084 hypothetical protein YP_001182542.1 PFAM: GPR1/FUN34/yaaH family protein; KEGG: son:SO3588 gpr1/fun34/YaaH family protein YP_001182543.1 KEGG: son:SO3587 hypothetical protein YP_001182544.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: shm:Shewmr7_3081 glyoxalase/bleomycin resistance protein/dioxygenase YP_001182545.1 PFAM: NADPH-dependent FMN reductase; KEGG: shm:Shewmr7_3080 NADPH-dependent FMN reductase YP_001182546.1 PFAM: Helix-turn-helix, type 11 domain protein; KEGG: she:Shewmr4_2998 putative transcriptional regulator YP_001182547.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: she:Shewmr4_2997 pseudouridine synthase, Rsu YP_001182548.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_3076 methyl-accepting chemotaxis sensory transducer YP_001182549.1 KEGG: shm:Shewmr7_3075 putative lipoprotein YP_001182550.1 KEGG: shm:Shewmr7_3074 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001182551.1 PFAM: protein of unknown function DUF152; KEGG: son:SO3578 conserved hypothetical protein TIGR00726 YP_001182552.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3072 ATPase AAA-2 domain protein YP_001182553.1 KEGG: shm:Shewmr7_3071 hypothetical protein YP_001182554.1 KEGG: son:SO3575 CDP-diacylglycerol--serine O-phosphatidyltransferase, putative; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001182555.1 KEGG: sfr:Sfri_1559 ISSod10, transposase OrfB YP_001182556.1 TIGRFAM: sodium pump decarboxylases, gamma subunit; PFAM: sodium pump decarboxylase, gamma subunit; KEGG: she:Shewmr4_2987 sodium pump decarboxylases, gamma subunit YP_001182557.1 catalyzes the formation of pyruvate from oxaloacetate YP_001182558.1 KEGG: she:Shewmr4_2985 sodium ion-translocating decarboxylase, beta subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit YP_001182559.1 KEGG: shm:Shewmr7_3066 hypothetical protein YP_001182560.1 PFAM: sodium:dicarboxylate symporter; KEGG: shm:Shewmr7_3065 sodium:dicarboxylate symporter YP_001182561.1 KEGG: she:Shewmr4_2982 hypothetical protein YP_001182562.1 PFAM: peptidase M16 domain protein; KEGG: she:Shewmr4_2981 peptidase M16 domain protein YP_001182563.1 involved in the first step of glutathione biosynthesis YP_001182564.1 KEGG: shm:Shewmr7_3061 hypothetical protein YP_001182565.1 KEGG: she:Shewmr4_2978 hypothetical protein YP_001182566.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: shm:Shewmr7_3059 diguanylate cyclase with GAF sensor YP_001182567.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001182568.1 KEGG: she:Shewmr4_2975 phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_001182569.1 putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_001182570.1 PFAM: von Willebrand factor, type A; KEGG: son:SO3552 von Willebrand factor type A domain protein YP_001182571.1 PFAM: sigma-70 region 2 domain protein; Sigma-70, region 4 type 2; KEGG: shm:Shewmr7_3054 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001182572.1 KEGG: she:Shewmr4_2971 hypothetical protein YP_001182573.1 PFAM: Hemerythrin HHE cation binding domain protein; KEGG: shm:Shewmr7_3052 hemerythrin HHE cation binding domain protein YP_001182574.1 KEGG: shm:Shewmr7_3051 hypothetical protein YP_001182575.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001182576.1 KEGG: shm:Shewmr7_3049 transaldolase; TIGRFAM: transaldolase; PFAM: Transaldolase YP_001182577.1 PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: son:SO3545 OmpA family protein YP_001182578.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: son:SO3542 putative phosphoketolase YP_001182579.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: she:Shewmr4_2964 amino acid carrier protein YP_001182580.1 PFAM: protein of unknown function DUF328; KEGG: shm:Shewmr7_3045 protein of unknown function DUF328 YP_001182581.1 PFAM: peptidase M20; peptidase M28; KEGG: she:Shewmr4_2962 peptidase M28 YP_001182582.1 PFAM: regulatory protein, ArsR; KEGG: shm:Shewmr7_3043 transcriptional regulator, ArsR family YP_001182583.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001182584.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: she:Shewmr4_2959 integral membrane protein MviN YP_001182585.1 KEGG: she:Shewmr4_2958 riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase YP_001182586.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001182587.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001182588.1 KEGG: shm:Shewmr7_3037 peptidylprolyl isomerase, FKBP-type YP_001182589.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001182590.1 TIGRFAM: type IV pilus modification protein PilV; KEGG: shm:Shewmr7_3035 type IV pilus modification protein PilV YP_001182591.1 KEGG: shm:Shewmr7_3034 prepilin-type cleavage/methylation-like protein YP_001182592.1 KEGG: she:Shewmr4_2951 type IV pilus assembly protein PilX YP_001182593.1 KEGG: she:Shewmr4_2950 type IV pilin biogenesis protein, putative YP_001182594.1 KEGG: shm:Shewmr7_3031 methylation site containing protein YP_001182595.1 KEGG: she:Shewmr4_2948 hypothetical protein YP_001182596.1 KEGG: shm:Shewmr7_3029 methylation site containing protein YP_001182597.1 KEGG: shm:Shewmr7_3028 methylation site containing protein YP_001182598.1 PFAM: nitrogen regulatory protein P-II; KEGG: shm:Shewmr7_3027 nitrogen regulatory protein P-II YP_001182599.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: shm:Shewmr7_3026 NADH dehydrogenase YP_001182600.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: shm:Shewmr7_3025 transcriptional regulator, LacI family YP_001182601.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_3024 TonB-dependent receptor YP_001182602.1 PFAM: glycoside hydrolase, family 20; Carbohydrate-binding, chitobiase/hexosaminidase-type domain protein; glycoside hydrolase, family 20 domain protein; KEGG: she:Shewmr4_2936 beta-N-acetylhexosaminidase YP_001182603.1 PFAM: ATPase, BadF/BadG/BcrA/BcrD type; KEGG: shm:Shewmr7_3017 ATPase, BadF/BadG/BcrA/BcrD type YP_001182604.1 PFAM: sugar isomerase (SIS); KEGG: shm:Shewmr7_3016 glutamine--fructose-6-phosphate transaminase (isomerizing) YP_001182605.1 KEGG: she:Shewmr4_2933 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase YP_001182606.1 KEGG: she:Shewmr4_2932 hypothetical protein YP_001182607.1 TIGRFAM: glucose/galactose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: son:SO3503 glucose/galactose transporter YP_001182608.1 KEGG: shm:Shewmr7_3012 hypothetical protein YP_001182609.1 PFAM: protein of unknown function DUF861, cupin_3; KEGG: shm:Shewmr7_3011 protein of unknown function DUF861, cupin_3 YP_001182610.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: she:Shewmr4_2928 methylmalonate-semialdehyde dehydrogenase YP_001182611.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_001182612.1 PFAM: aldehyde dehydrogenase; KEGG: she:Shewmr4_2926 aldehyde dehydrogenase (NAD(+)) YP_001182613.1 KEGG: son:SO4411 hypothetical protein YP_001182614.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; KEGG: shm:Shewmr7_3007 rare lipoprotein A YP_001182615.1 PFAM: Rhodanese domain protein; KEGG: son:SO1261 mercaptopyruvate sulfurtransferase YP_001182616.1 KEGG: son:SO1262 hypothetical protein YP_001182617.1 PFAM: FAD dependent oxidoreductase; KEGG: son:SO1264 hypothetical oxidoreductase YP_001182618.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; KEGG: son:SO1265 transcriptional regulator, putative YP_001182619.1 PFAM: peptidase C26; KEGG: she:Shewmr4_2920 peptidase C26 YP_001182620.1 PFAM: glutamine synthetase, catalytic region; KEGG: she:Shewmr4_2919 glutamate--ammonia ligase YP_001182621.1 PFAM: extracellular solute-binding protein, family 1; KEGG: she:Shewmr4_2918 extracellular solute-binding protein, family 1 YP_001182622.1 KEGG: shm:Shewmr7_2999 spermidine/putrescine ABC transporter ATPase subunit; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001182623.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2998 binding-protein-dependent transport systems inner membrane component YP_001182624.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2997 binding-protein-dependent transport systems inner membrane component YP_001182625.1 PFAM: FAD dependent oxidoreductase; KEGG: shm:Shewmr7_2996 FAD dependent oxidoreductase YP_001182626.1 KEGG: son:SO1275 succinate-semialdehyde dehydrogenase (NADP+); TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_001182627.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_001182628.1 PFAM: luciferase family protein; KEGG: she:Shewmr4_2911 luciferase family protein YP_001182629.1 TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor, type I/II extracellular region; major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_2992 amino acid/peptide transporter YP_001182630.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_2991 methyl-accepting chemotaxis sensory transducer YP_001182631.1 TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma factor RpoD domain protein; PFAM: sigma-70 1.1 domain protein; sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70, non-essential domain protein; sigma-70 region 1.2; KEGG: she:Shewmr4_2908 RNA polymerase, sigma 70 subunit, RpoD YP_001182632.1 KEGG: shm:Shewmr7_2989 DNA primase; TIGRFAM: DNA primase; PFAM: zinc finger, CHC2-family protein; TOPRIM domain protein; DNA primase DnaG, DnaB-binding; DNA primase catalytic core, N-terminal domain; SMART: Toprim sub domain protein YP_001182633.1 PFAM: GatB/Yqey domain protein; KEGG: she:Shewmr4_2906 GatB/YqeY domain protein YP_001182634.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001182635.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001182636.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001182637.1 TIGRFAM: dihydroneopterin aldolase; KEGG: shm:Shewmr7_2984 dihydroneopterin aldolase YP_001182638.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: she:Shewmr4_2901 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_001182639.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001182640.1 KEGG: shm:Shewmr7_2981 rRNA (guanine-N(1)-)-methyltransferase YP_001182641.1 KEGG: shm:Shewmr7_2980 major outer membrane lipoprotein, putative YP_001182642.1 PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase, HD sub domain; KEGG: shm:Shewmr7_2979 metal dependent phosphohydrolase YP_001182643.1 PFAM: Peptidoglycan-binding domain 1 protein; SMART: AAA ATPase; KEGG: she:Shewmr4_2896 peptidoglycan-binding domain 1 protein YP_001182644.1 KEGG: she:Shewmr4_2895 general secretion pathway protein B YP_001182645.1 PFAM: Citrate transporter; KEGG: she:Shewmr4_2894 citrate transporter YP_001182646.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001182647.1 Catalyzes the conversion of carbamoyl phosphate and l-aspartate to yield orthophosphate and n-carbamoyl-l-aspartate YP_001182648.1 PFAM: Cl- channel, voltage-gated family protein; KEGG: shm:Shewmr7_2973 Cl-channel, voltage-gated family protein YP_001182649.1 KEGG: she:Shewmr4_2890 hypothetical protein YP_001182650.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_001182651.1 KEGG: she:Shewmr4_2888 hypothetical protein YP_001182652.1 KEGG: shm:Shewmr7_2969 hypothetical protein YP_001182653.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001182654.1 PFAM: peptidase M23B; Opacity-associated protein A, N-terminal domain protein; KEGG: she:Shewmr4_2881 peptidase M23B YP_001182655.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001182656.1 KEGG: son:SO1317 hypothetical protein YP_001182657.1 KEGG: she:Shewmr4_2878 hypothetical protein YP_001182658.1 PFAM: protein of unknown function UPF0126; KEGG: shm:Shewmr7_2959 protein of unknown function UPF0126 YP_001182659.1 KEGG: shm:Shewmr7_2958 hypothetical protein YP_001182660.1 PFAM: cobalamin biosynthesis protein CbiB; KEGG: son:SO1321 CobD-related protein YP_001182661.1 PFAM: purine and other phosphorylases, family 1; KEGG: she:Shewmr4_2874 methylthioadenosine nucleosidase YP_001182662.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001182663.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_001182664.1 KEGG: shm:Shewmr7_2952 conserved hypothetical radical SAM protein; TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001182665.1 PFAM: Hpt domain protein; KEGG: shm:Shewmr7_2951 Hpt protein YP_001182666.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2950 transcriptional regulator, LysR family YP_001182667.1 KEGG: shm:Shewmr7_2949 putative adenylate/guanylate cyclase YP_001182668.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_001182669.1 hydrolyzes diadenosine polyphosphate YP_001182670.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; GAF domain protein; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein; KEGG: she:Shewmr4_2864 PTSINtr with GAF domain, PtsP YP_001182671.1 PFAM: protein of unknown function DUF81; KEGG: son:SO1333 hypothetical protein YP_001182672.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001182673.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001182674.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_001182675.1 KEGG: son:SO1337 hypothetical protein YP_001182676.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_001182677.1 PFAM: protein of unknown function DUF339; KEGG: shm:Shewmr7_2939 protein of unknown function DUF339 YP_001182678.1 KEGG: son:SO1340 hypothetical protein YP_001182679.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001182680.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001182681.1 PFAM: Anti sigma-E protein RseA family protein; Anti sigma-E protein RseA domain protein; KEGG: she:Shewmr4_2853 anti sigma-E protein, RseA YP_001182682.1 PFAM: MucB/RseB family protein; KEGG: son:SO1344 sigma-E factor regulatory protein RseB YP_001182683.1 PFAM: Positive regulator of sigma(E), RseC/MucC; KEGG: she:Shewmr4_2851 positive regulator of sigma E, RseC/MucC YP_001182684.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001182685.1 KEGG: shm:Shewmr7_2931 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B YP_001182686.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001182687.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001182688.1 TIGRFAM: DNA repair protein RecO; PFAM: Recombination protein O, RecO; KEGG: son:SO1350 DNA repair protein RecO YP_001182689.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001182690.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001182691.1 PFAM: protein of unknown function DUF962; KEGG: shm:Shewmr7_2925 protein of unknown function DUF962 YP_001182692.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: she:Shewmr4_2841 protein of unknown function DUF21 YP_001182693.1 PFAM: cytochrome c assembly protein; KEGG: shm:Shewmr7_2922 cytochrome c assembly protein YP_001182694.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_001182695.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001182696.1 Essential for efficient processing of 16S rRNA YP_001182697.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001182698.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001182699.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_001182700.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_001182701.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_001182702.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: shm:Shewmr7_2913 oxidoreductase FAD-binding domain protein YP_001182703.1 KEGG: she:Shewmr4_2830 hypothetical protein YP_001182704.1 TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: she:Shewmr4_2828 chorismate mutase YP_001182705.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001182706.1 PFAM: permease YjgP/YjgQ family protein; KEGG: she:Shewmr4_2826 permease YjgP/YjgQ family protein YP_001182707.1 PFAM: permease YjgP/YjgQ family protein; KEGG: shm:Shewmr7_2907 permease YjgP/YjgQ family protein YP_001182708.1 PFAM: RDD domain containing protein; KEGG: she:Shewmr4_2823 RDD domain containing protein YP_001182709.1 KEGG: shm:Shewmr7_2905 hypothetical protein YP_001182710.1 PFAM: protein of unknown function DUF486; KEGG: she:Shewmr4_2821 protein of unknown function DUF486 YP_001182711.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1374 acetyltransferase, GNAT family YP_001182712.1 PFAM: protein of unknown function DUF1449; KEGG: shm:Shewmr7_2900 protein of unknown function DUF1449 YP_001182713.1 PFAM: band 7 protein; KEGG: son:SO1377 hypothetical protein YP_001182714.1 KEGG: shm:Shewmr7_2577 decaheme cytochrome c YP_001182715.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: sbo:SBO_1458 putative oxidoreductase, Fe-S subunit YP_001182716.1 PFAM: aldehyde ferredoxin oxidoreductase; Aldehyde ferredoxin oxidoreductase-like; KEGG: ecj:JW5272 predicted oxidoreductase YP_001182718.1 TIGRFAM: intracellular protease, PfpI family; PFAM: ThiJ/PfpI domain protein; KEGG: son:SO1378 ThiJ/PfpI family protein YP_001182719.1 KEGG: son:SO1379 hypothetical protein YP_001182720.1 KEGG: shm:Shewmr7_2895 hypothetical protein YP_001182721.1 KEGG: shm:Shewmr7_2893 hypothetical protein YP_001182722.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_2892 DEAD/DEAH box helicase domain protein YP_001182723.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; KEGG: shm:Shewmr7_2891 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor YP_001182724.1 KEGG: son:SO1387 HD domain protein YP_001182725.1 PFAM: peptidase M24; KEGG: shm:Shewmr7_2890 peptidase M24 YP_001182726.1 PFAM: ROK family protein; KEGG: son:SO1389 ROK family protein YP_001182727.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO1390 peptidyl-prolyl cis-trans isomerase, FKBP-type YP_001182728.1 PFAM: short chain fatty acid transporter; KEGG: shm:Shewmr7_2886 short chain fatty acid transporter YP_001182729.1 PFAM: protein of unknown function DUF1294; KEGG: son:SO1395 membrane protein,putative YP_001182730.1 PFAM: protein of unknown function DUF405; protein of unknown function DUF418; KEGG: son:SO1396 hypothetical protein YP_001182731.1 PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: son:SO1397 cytosine deaminase YP_001182732.1 KEGG: shm:Shewmr7_2880 hypothetical protein YP_001182733.1 PFAM: protein of unknown function DUF368; KEGG: shm:Shewmr7_2879 protein of unknown function DUF368 YP_001182734.1 KEGG: shm:Shewmr7_2878 hypothetical protein YP_001182735.1 PFAM: YheO domain protein; KEGG: son:SO1402 hypothetical protein YP_001182736.1 PFAM: protein of unknown function DUF1063; KEGG: shm:Shewmr7_2876 protein of unknown function DUF1063 YP_001182737.1 PFAM: regulatory protein, ArsR; KEGG: dps:DP0944 similar to ArsR-family transcription regulator YP_001182738.1 TIGRFAM: redox-active disulfide protein 2; KEGG: plt:Plut_1705 redox-active disulfide protein 2 YP_001182739.1 KEGG: mhu:Mhun_0869 hypothetical protein YP_001182740.1 PFAM: cytochrome c biogenesis protein, transmembrane region; KEGG: bth:BT0800 hypothetical protein YP_001182741.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: sbo:SBO_3501 arsenate reductase YP_001182742.1 TIGRFAM: arsenical pump membrane protein; PFAM: Arsenical pump membrane protein; Citrate transporter; KEGG: sbo:SBO_3500 arsenical pump membrane protein YP_001182743.1 PFAM: glutathione synthase, ATP-binding; KEGG: vfi:VF0976 glutathione synthetase YP_001182744.1 PFAM: permease; KEGG: son:SO0503 hypothetical protein YP_001182745.1 PFAM: regulatory protein, ArsR; KEGG: son:SO0502 transcriptional regulator, ArsR family YP_001182746.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: sfr:Sfri_4004 transcriptional regulator, ArsR family protein YP_001182747.1 PFAM: regulatory protein, ArsR; KEGG: son:SO0532 arsenical resistence operon repressor YP_001182748.1 PFAM: permease; KEGG: sfr:Sfri_1725 permease YP_001182749.1 KEGG: cps:CPS_3356 redox-active disulfide protein 2 YP_001182750.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate YP_001182751.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfr:Sfri_4001 major facilitator superfamily MFS_1 YP_001182752.1 KEGG: hch:HCH_00506 hypothetical protein YP_001182753.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sfr:Sfri_0790 sulphate transporter YP_001182754.1 PFAM: UspA domain protein; KEGG: sfr:Sfri_0791 UspA domain protein YP_001182756.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001182757.1 PFAM: cyclase/dehydrase; KEGG: shm:Shewmr7_2853 cyclase/dehydrase YP_001182758.1 PFAM: protein of unknown function UPF0125; KEGG: shm:Shewmr7_2852 protein of unknown function UPF0125 YP_001182759.1 PFAM: SmpA/OmlA domain protein; KEGG: shm:Shewmr7_2851 SmpA/OmlA domain protein YP_001182760.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: she:Shewmr4_2772 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase YP_001182761.1 KEGG: shm:Shewmr7_2849 hypothetical protein YP_001182762.1 KEGG: she:Shewmr4_2770 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: Tetratricopeptide domain protein YP_001182763.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: shm:Shewmr7_2847 potassium efflux system protein YP_001182764.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO1482 TonB-dependent receptor, putative YP_001182765.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001182766.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: son:SO1484 isocitrate lyase YP_001182767.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_2843 thioesterase superfamily protein YP_001182768.1 KEGG: son:SO1487 hypothetical protein YP_001182769.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sfr:Sfri_3431 NADH dehydrogenase YP_001182770.1 KEGG: shm:Shewmr7_2841 hypothetical protein YP_001182771.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: son:SO1490 alcohol dehydrogenase II YP_001182772.1 PFAM: regulatory protein, MarR; KEGG: she:Shewmr4_2761 transcriptional regulator, MarR family YP_001182773.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: shm:Shewmr7_2838 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001182774.1 KEGG: shm:Shewmr7_2837 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase, family 77 YP_001182775.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001182776.1 KEGG: son:SO1495 glycogen operon protein; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001182777.1 KEGG: she:Shewmr4_2756 glycogen/starch/alpha-glucan phosphorylases; TIGRFAM: glycogen/starch/alpha-glucan phosphorylases; PFAM: glycosyl transferase, family 35 YP_001182778.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001182779.1 PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein; KEGG: shm:Shewmr7_2832 starch synthase YP_001182780.1 KEGG: shm:Shewmr7_2831 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; 5TM Receptors of the LytS-YhcK type, transmembrane region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001182781.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO1501 ATP-dependent RNA helicase, DEAD box family YP_001182782.1 PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein; KEGG: son:SO1502 cobalamin synthesis protein/P47K family protein YP_001182783.1 KEGG: son:SO1503 ABC transporter, periplasmic substrate-binding protein, putative YP_001182784.1 KEGG: son:SO1504 hypothetical protein YP_001182785.1 PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_2748 major facilitator superfamily MFS_1 YP_001182786.1 PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO1506 MATE efflux family protein YP_001182787.1 KEGG: shm:Shewmr7_2824 hypothetical protein YP_001182790.1 KEGG: bpa:BPP0522 hypothetical protein YP_001182791.1 PFAM: protein of unknown function DUF1568; KEGG: son:SO1890 hypothetical protein YP_001182792.1 PFAM: putative esterase; KEGG: sdn:Sden_3719 putative esterase YP_001182793.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdn:Sden_3086 GCN5-related N-acetyltransferase YP_001182794.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_2812 AAA ATPase, central domain protein YP_001182795.1 PFAM: protein of unknown function DUF162; KEGG: she:Shewmr4_2738 protein of unknown function DUF162 YP_001182796.1 KEGG: shm:Shewmr7_2810 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001182797.1 PFAM: protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: she:Shewmr4_2736 protein of unknown function DUF224, cysteine-rich region domain protein YP_001182798.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; FAD linked oxidase domain protein; KEGG: son:SO1521 iron-sulfur cluster-binding protein YP_001182799.1 PFAM: L-lactate permease; KEGG: son:SO1522 L-lactate permease, putative YP_001182800.1 catalyzes the phosphorylation of NAD to NADP YP_001182801.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001182802.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001182803.1 PFAM: Polyprenyl synthetase; KEGG: son:SO1526 geranyltranstransferase YP_001182804.1 TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII, small subunit; KEGG: shm:Shewmr7_2802 exodeoxyribonuclease VII, small subunit YP_001182805.1 Homologous to MotA in E. coli and Salmonella. With PomB forms the ion channels that couple flagellar rotation to sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. YP_001182806.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; Vibrio parahaemolyticus protein is associated with the polar flagella YP_001182807.1 Required for the synthesis of the thiazole moiety YP_001182808.1 KEGG: shm:Shewmr7_2796 hypothetical protein YP_001182809.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_001182810.1 KEGG: shm:Shewmr7_2794 hypothetical protein YP_001182811.1 PFAM: protein of unknown function DUF423; KEGG: son:SO1535 hypothetical protein YP_001182812.1 KEGG: she:Shewmr4_2721 hypothetical protein YP_001182813.1 catalyzes the formation of 2-oxoglutarate from isocitrate YP_001182814.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; KEGG: she:Shewmr4_2719 peptidase S9, prolyl oligopeptidase active site domain protein YP_001182815.1 KEGG: she:Shewmr4_2717 hypothetical protein YP_001182816.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_001182817.1 PFAM: conserved hypothetical protein 730; KEGG: shm:Shewmr7_2783 conserved hypothetical protein 730 YP_001182818.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_2782 diguanylate cyclase YP_001182819.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_2781 TPR repeat-containing protein YP_001182820.1 PFAM: peptidase M61 domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: she:Shewmr4_2712 peptidase M61 domain protein YP_001182821.1 Required for efficient pilin antigenic variation YP_001182822.1 PFAM: porin, Gram-negative type; KEGG: she:Shewmr4_2710 porin, gram-negative type YP_001182823.1 TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_2777 two component transcriptional regulator, winged helix family YP_001182824.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: son:SO1559 phosphate regulon sensor protein PhoR YP_001182825.1 TIGRFAM: phosphate binding protein; KEGG: she:Shewmr4_2707 phosphate binding protein YP_001182826.1 PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: son:SO1561 peptidase, M1 family YP_001182827.1 PFAM: glutathione peroxidase; KEGG: she:Shewmr4_2705 glutathione peroxidase YP_001182828.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: she:Shewmr4_2704 MgtE intracellular region YP_001182829.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_2703 GCN5-related N-acetyltransferase YP_001182830.1 PFAM: YfaZ family protein; KEGG: she:Shewmr4_2702 YfaZ family protein YP_001182831.1 KEGG: she:Shewmr4_2698 hypothetical protein YP_001182832.1 PFAM: Fmu (Sun) domain protein; KEGG: son:SO1575 NOL1/NOP2/sun family putative RNA methylase YP_001182833.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: shm:Shewmr7_2764 glutathione S-transferase, N-terminal domain protein YP_001182834.1 KEGG: she:Shewmr4_2693 hypothetical protein YP_001182835.1 TIGRFAM: TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO1580 TonB-dependent heme receptor YP_001182836.1 PFAM: PhnA protein-like; SMART: PhnA protein N-terminal, proteobacterial; KEGG: son:SO1581 PhnA protein YP_001182837.1 PFAM: major facilitator superfamily MFS_1; KEGG: pau:PA14_03550 putative MFS transporter YP_001182838.1 PFAM: regulatory protein, MarR; KEGG: shm:Shewmr7_2759 transcriptional regulator, MarR family YP_001182839.1 PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: son:SO1583 hypothetical protein YP_001182840.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: sdn:Sden_2638 chemotaxis sensory transducer YP_001182841.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: son:SO1585 fumarylacetoacetate hydrolase family protein YP_001182842.1 KEGG: she:Shewmr4_2686 hypothetical protein YP_001182843.1 KEGG: son:SO1589 hypothetical protein YP_001182844.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria; KEGG: shm:Shewmr7_2744 transport-associated YP_001182845.1 KEGG: shm:Shewmr7_2743 hypothetical protein YP_001182846.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_2742 sigma54 specific transcriptional regulator, fis family YP_001182847.1 PFAM: Dual specificity protein phosphatase; diacylglycerol kinase, catalytic region; KEGG: she:Shewmr4_2673 dual specificity protein phosphatase YP_001182848.1 KEGG: shm:Shewmr7_2740 hypothetical protein YP_001182849.1 PFAM: protein of unknown function DUF1328; KEGG: shm:Shewmr7_2739 protein of unknown function DUF1328 YP_001182850.1 KEGG: shm:Shewmr7_2736 2-nitropropane dioxygenase, NPD YP_001182851.1 PFAM: beta-ketoacyl synthase; Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; KEGG: she:Shewmr4_2668 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ YP_001182852.1 KEGG: shm:Shewmr7_2734 omega-3 polyunsaturated fatty acid synthase PfaB YP_001182853.1 PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_2733 beta-ketoacyl synthase YP_001182854.1 KEGG: shm:Shewmr7_2732 transcriptional regulator, putative YP_001182855.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: shm:Shewmr7_2731 4'-phosphopantetheinyl transferase YP_001182856.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_001182857.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_001182858.1 KEGG: son:SO1610 hypothetical protein YP_001182859.1 KEGG: shm:Shewmr7_2725 hypothetical protein YP_001182860.1 KEGG: shm:Shewmr7_2724 hypothetical protein YP_001182861.1 KEGG: son:SO1613 hypothetical protein YP_001182862.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1614 acetyltransferase, GNAT family YP_001182863.1 KEGG: son:SO1617 hypothetical protein YP_001182864.1 KEGG: she:Shewmr4_2652 hypothetical protein YP_001182865.1 PFAM: protein of unknown function DUF446; KEGG: shm:Shewmr7_2718 protein of unknown function DUF446 YP_001182866.1 PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_2717 pseudouridylate synthase YP_001182868.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001182869.1 TIGRFAM: PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS, EIIB protein; phosphotransferase system, EIIC; KEGG: shm:Shewmr7_2715 PTS system, glucose-like IIB subunint YP_001182870.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001182871.1 KEGG: shm:Shewmr7_2713 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: CBS domain containing protein; GAF domain protein; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001182872.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001182873.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001182874.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001182875.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001182876.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001182877.1 Catalyzes the phosphorylation of UMP to UDP YP_001182878.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001182879.1 KEGG: son:SO1633 undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_001182880.1 PFAM: phosphatidate cytidylyltransferase; KEGG: shm:Shewmr7_2703 phosphatidate cytidylyltransferase YP_001182881.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001182882.1 TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: shm:Shewmr7_2701 putative membrane-associated zinc metalloprotease YP_001182883.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: shm:Shewmr7_2700 surface antigen (D15) YP_001182884.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: shm:Shewmr7_2699 outer membrane chaperone Skp (OmpH) YP_001182885.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001182886.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001182887.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001182888.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001182889.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001182890.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001182891.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; KEGG: she:Shewmr4_2625 tRNA(Ile)-lysidine synthetase YP_001182892.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO1646 GGDEF family protein YP_001182893.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: shm:Shewmr7_2689 cold-shock DNA-binding domain protein YP_001182894.1 PFAM: protein of unknown function DUF885; KEGG: she:Shewmr4_2621 protein of unknown function DUF885 YP_001182895.1 PFAM: SNF2-related protein; helicase domain protein; zinc finger, SWIM domain protein; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_2687 SNF2-related protein YP_001182896.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; KEGG: she:Shewmr4_2619 PHP C-terminal domain protein YP_001182897.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: shm:Shewmr7_2684 3'(2'),5'-bisphosphate nucleotidase YP_001182898.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_001182899.1 PFAM: protein of unknown function DUF218; KEGG: son:SO1657 hypothetical protein YP_001182900.1 KEGG: shm:Shewmr7_2681 hypothetical protein YP_001182901.1 KEGG: son:SO0729 hypothetical protein YP_001182902.1 PFAM: GCN5-related N-acetyltransferase; KEGG: pat:Patl_0928 GCN5-related N-acetyltransferase YP_001182903.1 KEGG: ccr:CC3235 hypothetical protein YP_001182904.1 KEGG: son:SO2212 transposase, IS91 family, putative YP_001182906.1 KEGG: son:SO1659 decaheme cytochrome c YP_001182907.1 PFAM: regulatory protein, LysR; KEGG: son:SO1661 transcriptional regulator, LysR family YP_001182908.1 PFAM: protein of unknown function DUF583; KEGG: shm:Shewmr7_2678 protein of unknown function DUF583 YP_001182909.1 TIGRFAM: ferredoxin-type protein NapF; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_2677 ferredoxin-type protein NapF YP_001182910.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: she:Shewmr4_2609 UDP-glucose 4-epimerase YP_001182911.1 KEGG: shm:Shewmr7_2675 UTP-glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase YP_001182912.1 phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin YP_001182913.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_001182914.1 PFAM: sigma-54 factor, interaction domain-containing protein; amino acid-binding ACT domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_2672 transcriptional regulator, TyrR YP_001182915.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: son:SO1670 fumarylacetoacetate hydrolase family protein YP_001182916.1 TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: son:SO1671 glutathione S-transferase family protein YP_001182917.1 PFAM: protein of unknown function DUF925; KEGG: she:Shewmr4_2602 protein of unknown function DUF925 YP_001182918.1 receptor for colicin S4 YP_001182919.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: son:SO1674 short chain dehydrogenase family protein YP_001182920.1 KEGG: shm:Shewmr7_2666 hypothetical protein YP_001182921.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_001182922.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: vch:VCA0220 hemolysin secretion protein HylB YP_001182923.1 KEGG: shm:Shewmr7_2664 acetyl-CoA acetyltransferases; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase YP_001182924.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: she:Shewmr4_2596 methylmalonate-semialdehyde dehydrogenase YP_001182925.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: shm:Shewmr7_2662 acyl-CoA dehydrogenase domain protein YP_001182926.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001182927.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: shm:Shewmr7_2660 enoyl-CoA hydratase/isomerase YP_001182928.1 KEGG: shm:Shewmr7_2659 3-hydroxyisobutyrate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding YP_001182929.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001182930.1 KEGG: shm:Shewmr7_2657 hypothetical protein YP_001182931.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; KEGG: she:Shewmr4_2589 peptidase S9, prolyl oligopeptidase active site domain protein YP_001182932.1 PFAM: regulatory protein, MerR; KEGG: she:Shewmr4_2588 transcriptional regulator, MerR family YP_001182933.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: she:Shewmr4_2587 copper-translocating P-type ATPase YP_001182934.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_2653 ABC transporter related YP_001182935.1 PFAM: Lipocalin-related protein and Bos/Can/Equ allergen; Lipocalin family protein; KEGG: son:SO1691 lipoprotein Blc YP_001182936.1 PFAM: FAD linked oxidase domain protein; Berberine/berberine domain protein; KEGG: shm:Shewmr7_2650 FAD linked oxidase domain protein YP_001182937.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: she:Shewmr4_2582 diguanylate cyclase YP_001182938.1 KEGG: she:Shewmr4_2581 hypothetical protein YP_001182939.1 PFAM: transcriptional regulator domain protein; Tetratricopeptide TPR_2 repeat protein; KEGG: shm:Shewmr7_2647 transcriptional regulator, CadC YP_001182940.1 KEGG: son:SO1700 hypothetical protein YP_001182941.1 KEGG: shm:Shewmr7_2645 hypothetical protein YP_001182942.1 KEGG: shm:Shewmr7_2644 hypothetical protein YP_001182943.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_2643 transcriptional regulator, TetR family YP_001182944.1 PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_2575 secretion protein HlyD family protein YP_001182945.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: she:Shewmr4_2574 ABC transporter related YP_001182946.1 PFAM: ABC-2 type transporter; KEGG: shm:Shewmr7_2640 ABC-2 type transporter YP_001182947.1 PFAM: acetyl-CoA hydrolase/transferase; KEGG: son:SO1708 4-hydroxybutyrate coenzyme A transferase YP_001182948.1 KEGG: son:SO1710 hypothetical protein YP_001182949.1 KEGG: son:SO1711 hypothetical protein YP_001182950.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: ppu:PP_5020 methyl-accepting chemotaxis transducer YP_001182952.1 PFAM: protein of unknown function DUF1415; KEGG: shm:Shewmr7_2635 protein of unknown function DUF1415 YP_001182953.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shm:Shewmr7_2634 lysine exporter protein (LysE/YggA) YP_001182954.1 KEGG: shm:Shewmr7_2632 hypothetical protein YP_001182956.1 KEGG: shm:Shewmr7_2631 hypothetical protein YP_001182957.1 PFAM: amino acid-binding ACT domain protein; KEGG: son:SO1722 ACT domain protein YP_001182958.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2627 binding-protein-dependent transport systems inner membrane component YP_001182959.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: she:Shewmr4_2559 phosphate ABC transporter, inner membrane subunit PstA YP_001182960.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001182961.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_001182962.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: ilo:IL0610 methyl-accepting chemotaxis protein (contains HAMP domain) YP_001182963.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: son:SO1734 glyoxalase family protein YP_001182964.1 KEGG: son:SO1736 hypothetical protein YP_001182965.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: she:Shewmr4_2552 choline/carnitine/betaine transporter YP_001182966.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: son:SO1738 hypothetical protein YP_001182967.1 PFAM: protein of unknown function DUF1289; KEGG: shm:Shewmr7_2617 protein of unknown function DUF1289 YP_001182968.1 KEGG: son:SO1741 hypothetical protein YP_001182969.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001182970.1 PFAM: alpha/beta hydrolase fold; KEGG: she:Shewmr4_2547 alpha/beta hydrolase fold YP_001182971.1 Catalyzes the specific recognition and activation of amino acids during peptide synthesis YP_001182972.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility C-terminal domain; KEGG: shm:Shewmr7_2612 3-beta hydroxysteroid dehydrogenase/isomerase YP_001182973.1 KEGG: pfo:Pfl_2272 hypothetical protein YP_001182974.1 KEGG: shm:Shewmr7_2611 hypothetical protein YP_001182975.1 PFAM: Integral membrane protein TerC; KEGG: son:SO1747 membrane protein, putative YP_001182976.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1750 ABC transporter, ATP-binding protein YP_001182977.1 KEGG: son:SO1751 hypothetical protein YP_001182978.1 PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; KEGG: she:Shewmr4_2541 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I YP_001182979.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: shm:Shewmr7_2607 glyoxalase/bleomycin resistance protein/dioxygenase YP_001182980.1 PFAM: transcription activator, effector binding; KEGG: son:SO1757 hypothetical protein YP_001182981.1 PFAM: Helix-turn-helix, type 11 domain protein; KEGG: she:Shewmr4_2538 helix-turn-helix, type 11 domain protein YP_001182982.1 PFAM: branched-chain amino acid transport; KEGG: she:Shewmr4_2529 branched-chain amino acid transport YP_001182983.1 PFAM: AzlC family protein; KEGG: she:Shewmr4_2528 AzlC family protein YP_001182984.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: son:SO1762 transcriptional regulator, AraC/XylS family YP_001182985.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: son:SO1763 streptogramin A acetyl transferase YP_001182986.1 PFAM: protein of unknown function DUF1706; KEGG: son:SO1764 hypothetical protein YP_001182987.1 KEGG: son:SO1765 hypothetical protein YP_001182988.1 KEGG: cps:CPS_2655 hypothetical protein YP_001182989.1 PFAM: Integrase, catalytic region; KEGG: vpa:VP1787 putative transposase YP_001182990.1 PFAM: transposase IS3/IS911 family protein; KEGG: vpa:VP1788 putative transposase YP_001182991.1 KEGG: son:SO1765 hypothetical protein YP_001182992.1 KEGG: mxa:MXAN_2894 hypothetical protein YP_001182993.1 PFAM: Pyridoxal-dependent decarboxylase; KEGG: she:Shewmr4_2520 pyridoxal-dependent decarboxylase YP_001182994.1 PFAM: glycerate kinase; KEGG: shm:Shewmr7_2587 glycerate kinase YP_001182995.1 PFAM: Gluconate transporter; Citrate transporter; KEGG: shm:Shewmr7_2586 gluconate transporter YP_001182996.1 PFAM: Catalase domain protein; KEGG: she:Shewmr4_2517 catalase domain protein YP_001182997.1 PFAM: sugar diacid recognition domain protein; KEGG: shm:Shewmr7_2584 transcriptional regulator, CdaR YP_001182998.1 KEGG: shm:Shewmr7_2582 phage SPO1 DNA polymerase domain protein YP_001182999.1 KEGG: she:Shewmr4_2513 hypothetical protein YP_001183000.1 KEGG: son:SO1776 outer membrane protein precursor MtrB YP_001183001.1 TIGRFAM: cytochrome C family protein; KEGG: son:SO1777 decaheme cytochrome c MtrA YP_001183002.1 KEGG: shm:Shewmr7_2578 decaheme cytochrome c YP_001183003.1 KEGG: son:SO1779 decaheme cytochrome c YP_001183004.1 PFAM: FeoA family protein; KEGG: shm:Shewmr7_2573 FeoA family protein YP_001183005.1 TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; nucleoside recognition domain protein; Miro domain protein; KEGG: son:SO1784 ferrous iron transport protein B YP_001183006.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001183007.1 PFAM: protein of unknown function DUF1282; KEGG: she:Shewmr4_2502 protein of unknown function DUF1282 YP_001183008.1 PFAM: tRNA--hydroxylase; KEGG: she:Shewmr4_2501 tRNA--hydroxylase YP_001183009.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_001183010.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: son:SO1790 peptidyl-prolyl cis-trans isomerase B YP_001183011.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001183012.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001183013.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001183014.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001183015.1 binds and unfolds substrates as part of the ClpXP protease YP_001183016.1 KEGG: shm:Shewmr7_2561 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16, lon domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001183017.1 PFAM: histone family protein DNA-binding protein; KEGG: shm:Shewmr7_2560 histone family protein DNA-binding protein YP_001183018.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: she:Shewmr4_2491 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001183019.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_001183020.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1801 peptide ABC transporter, ATP-binding protein YP_001183021.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; KEGG: shm:Shewmr7_2555 oligopeptide/dipeptide ABC transporter, ATPase subunit YP_001183022.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2554 binding-protein-dependent transport systems inner membrane component YP_001183023.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: she:Shewmr4_2485 binding-protein-dependent transport systems inner membrane component YP_001183024.1 PFAM: extracellular solute-binding protein, family 5; KEGG: shm:Shewmr7_2552 extracellular solute-binding protein, family 5 YP_001183025.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_2551 transcriptional regulator, fis family YP_001183026.1 PFAM: PspA/IM30 family protein; KEGG: son:SO1807 phage shock protein A YP_001183027.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_001183028.1 PFAM: PspC domain protein; KEGG: shm:Shewmr7_2548 phage shock protein C, PspC YP_001183029.1 PFAM: protein of unknown function DUF463, YcjX family protein; KEGG: shm:Shewmr7_2547 protein of unknown function DUF463, YcjX family protein YP_001183030.1 PFAM: conserved hypothetical protein 1620; KEGG: she:Shewmr4_2478 conserved hypothetical protein 1620 YP_001183031.1 KEGG: she:Shewmr4_2477 methionine gamma-lyase; TIGRFAM: methionine gamma-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001183032.1 KEGG: shm:Shewmr7_2544 competence protein ComEA helix-hairpin-helix repeat protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding, class 1 YP_001183033.1 KEGG: son:SO1814 hypothetical protein YP_001183034.1 KEGG: she:Shewmr4_2473 hypothetical protein YP_001183035.1 KEGG: she:Shewmr4_2472 primosomal replication protein N'', putative YP_001183036.1 PFAM: protein of unknown function DUF81; KEGG: shm:Shewmr7_2539 protein of unknown function DUF81 YP_001183037.1 helicase involved in DNA repair and perhaps also replication YP_001183038.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_001183039.1 PFAM: porin, Gram-negative type; KEGG: she:Shewmr4_2468 porin, gram-negative type YP_001183040.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO1822 TonB-dependent receptor, putative YP_001183041.1 KEGG: shm:Shewmr7_2534 hypothetical protein YP_001183042.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: shm:Shewmr7_2533 MotA/TolQ/ExbB proton channel YP_001183043.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: she:Shewmr4_2462 MotA/TolQ/ExbB proton channel YP_001183044.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: shm:Shewmr7_2531 biopolymer transport protein ExbD/TolR YP_001183045.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: shm:Shewmr7_2530 TonB family protein YP_001183046.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_2529 TPR repeat-containing protein YP_001183047.1 PFAM: GGDEF domain containing protein; KEGG: son:SO1830 GGDEF domain protein YP_001183048.1 PFAM: protein of unknown function DUF885; KEGG: she:Shewmr4_2457 protein of unknown function DUF885 YP_001183049.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: shm:Shewmr7_2526 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001183050.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1834 acetyltransferase, GNAT family YP_001183051.1 KEGG: shm:Shewmr7_2524 RNA-binding S4 domain protein YP_001183052.1 PFAM: protein of unknown function DUF1260; KEGG: son:SO1836 hypothetical protein YP_001183053.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2522 transcriptional regulator, LysR family YP_001183054.1 PFAM: protein of unknown function DUF81; KEGG: son:SO2846 hypothetical protein YP_001183055.1 TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase; KEGG: shm:Shewmr7_2520 nuclease SbcCD, D subunit YP_001183056.1 PFAM: SMC domain protein; KEGG: she:Shewmr4_2449 SMC domain protein YP_001183057.1 PFAM: peptidase M23B; Opacity-associated protein A; KEGG: shm:Shewmr7_2518 peptidase M23B YP_001183058.1 KEGG: son:SO2841 hypothetical protein YP_001183059.1 PFAM: protein of unknown function DUF45; KEGG: son:SO2840 hypothetical protein YP_001183060.1 KEGG: son:SO2839 hypothetical protein YP_001183061.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: she:Shewmr4_2444 DEAD/DEAH box helicase domain protein YP_001183062.1 PFAM: Patatin; KEGG: son:SO2836 hypothetical protein YP_001183063.1 KEGG: shm:Shewmr7_2512 hypothetical protein YP_001183064.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_001183065.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_001183066.1 KEGG: she:Shewmr4_2439 hypothetical protein YP_001183067.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_001183068.1 KEGG: son:SO2830 hypothetical protein YP_001183069.1 KEGG: son:SO2829 hypothetical protein YP_001183070.1 KEGG: she:Shewmr4_2434 hypothetical protein YP_001183071.1 PFAM: carbon starvation protein CstA; KEGG: she:Shewmr4_2433 carbon starvation protein CstA YP_001183072.1 unknown function; when overproduced it confers drug-resistance YP_001183073.1 PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type, transmembrane region; KEGG: son:SO2822 sensor histidine kinase YP_001183074.1 KEGG: shm:Shewmr7_2500 hypothetical protein YP_001183075.1 KEGG: shm:Shewmr7_2499 RepA domain protein YP_001183076.1 KEGG: son:SO2808 hypothetical protein YP_001183077.1 PFAM: type IV pilus assembly PilZ; KEGG: shm:Shewmr7_2497 type IV pilus assembly PilZ YP_001183078.1 PFAM: phosphate-starvation-inducible E; KEGG: shm:Shewmr7_2496 phosphate-starvation-inducible E YP_001183079.1 KEGG: shm:Shewmr7_2494 hypothetical protein YP_001183080.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG: shm:Shewmr7_2493 DNA internalization-related competence protein ComEC/Rec2 YP_001183081.1 KEGG: son:SO2802 ABC transporter, ATP-binding protein MsbA; TIGRFAM: lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001183082.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001183083.1 PFAM: protein of unknown function DUF343; KEGG: son:SO2800 hypothetical protein YP_001183084.1 KEGG: son:SO2799 lipoprotein, putative YP_001183085.1 KEGG: she:Shewmr4_2418 hypothetical protein YP_001183086.1 PFAM: glutaredoxin; Glutathione S-transferase, N-terminal domain; KEGG: shm:Shewmr7_2487 glutaredoxin YP_001183087.1 PFAM: protein of unknown function DUF748; KEGG: she:Shewmr4_2416 protein of unknown function DUF748 YP_001183088.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: son:SO2795 glyoxalase family protein YP_001183089.1 KEGG: she:Shewmr4_2414 hypothetical protein YP_001183090.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: she:Shewmr4_2413 glyoxalase/bleomycin resistance protein/dioxygenase YP_001183091.1 PFAM: protein of unknown function DUF1289; KEGG: son:SO2792 hypothetical protein YP_001183092.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001183093.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_001183094.1 KEGG: son:SO2789 hypothetical protein YP_001183095.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_001183096.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: shm:Shewmr7_2477 cold-shock DNA-binding domain protein YP_001183097.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: she:Shewmr4_2405 ribonuclease, Rne/Rng family YP_001183098.1 KEGG: shm:Shewmr7_2474 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001183099.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: she:Shewmr4_2403 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_001183100.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: son:SO2782 maf protein, putative YP_001183101.1 PFAM: protein of unknown function DUF177; KEGG: shm:Shewmr7_2471 protein of unknown function DUF177 YP_001183102.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001183103.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001183104.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001183105.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein; KEGG: shm:Shewmr7_2467 malonyl CoA-acyl carrier protein transacylase YP_001183106.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: son:SO2776 3-oxoacyl-[acyl-carrier protein] reductase YP_001183107.1 carries the fatty acid chain in fatty acid biosynthesis YP_001183108.1 PFAM: beta-ketoacyl synthase; KEGG: son:SO2774 3-oxoacyl-(acyl-carrier-protein) synthase II YP_001183109.1 KEGG: shm:Shewmr7_2463 hypothetical protein YP_001183110.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_2462 thioesterase superfamily protein YP_001183111.1 PFAM: oxidoreductase domain protein; NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: she:Shewmr4_2391 6-phosphogluconate dehydrogenase, NAD-binding YP_001183112.1 PFAM: Aldose 1-epimerase; KEGG: shm:Shewmr7_2460 aldose 1-epimerase YP_001183113.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: she:Shewmr4_2387 acyl-CoA dehydrogenase domain protein YP_001183114.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_2386 TonB-dependent siderophore receptor YP_001183115.1 PFAM: Patatin; KEGG: she:Shewmr4_2385 patatin YP_001183116.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_001183117.1 PFAM: peptidase M28; KEGG: shm:Shewmr7_2455 peptidase M28 YP_001183118.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO2762 nagD protein YP_001183119.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001183120.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001183121.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001183122.1 PFAM: Gluconate transporter; Na+/H+ antiporter NhaC; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: son:SO2757 membrane protein, putative YP_001183123.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shm:Shewmr7_2448 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_001183124.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_001183125.1 PFAM: OmpA/MotB domain protein; KEGG: she:Shewmr4_2374 OmpA/MotB domain protein YP_001183126.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller; KEGG: shm:Shewmr7_2445 prolyl oligopeptidase YP_001183127.1 TIGRFAM: 4-hydroxybenzoyl-CoA thioesterase; PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_2444 4-hydroxybenzoyl-CoA thioesterase YP_001183128.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: shm:Shewmr7_2443 MotA/TolQ/ExbB proton channel YP_001183129.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: she:Shewmr4_2370 biopolymer transport protein ExbD/TolR YP_001183130.1 PFAM: TolA family protein; KEGG: she:Shewmr4_2369 TolA family protein YP_001183131.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001183132.1 TIGRFAM: OmpA domain protein; PFAM: OmpA/MotB domain protein; KEGG: shm:Shewmr7_2439 OmpA/MotB domain protein YP_001183133.1 TIGRFAM: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_2438 hypothetical protein YP_001183134.1 KEGG: shm:Shewmr7_1590 hypothetical protein YP_001183135.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_001183136.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: shm:Shewmr7_1592 peptidyl-dipeptidase DCP YP_001183137.1 SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: shm:Shewmr7_1593 prolyl 4-hydroxylase, alpha subunit YP_001183138.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_1594 GCN5-related N-acetyltransferase YP_001183139.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_1595 GCN5-related N-acetyltransferase YP_001183140.1 KEGG: shm:Shewmr7_1596 hypothetical protein YP_001183141.1 KEGG: shm:Shewmr7_1597 hypothetical protein YP_001183142.1 KEGG: son:SO1839 hypothetical protein YP_001183143.1 KEGG: son:SO1840 hypothetical protein YP_001183144.1 KEGG: shm:Shewmr7_1599 hypothetical protein YP_001183145.1 KEGG: shm:Shewmr7_1600 hypothetical protein YP_001183146.1 PFAM: PKD domain containing protein; Endonuclease/exonuclease/phosphatase; KEGG: son:SO1844 extracellular nuclease, putative YP_001183148.1 PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: son:SO2528 site-specific recombinase, phage integrase family YP_001183149.1 PFAM: putative transposase; KEGG: son:SO2212 transposase, IS91 family, putative YP_001183151.1 KEGG: son:SO1845 hypothetical protein YP_001183152.1 KEGG: shm:Shewmr7_1603 hypothetical protein YP_001183153.1 KEGG: she:Shewmr4_1537 hypothetical protein YP_001183154.1 KEGG: son:SO1849 hypothetical protein YP_001183155.1 PFAM: heat shock protein DnaJ domain protein; KEGG: son:SO1850 DnaJ domain protein YP_001183156.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_001183157.1 PFAM: glutaredoxin 2; KEGG: she:Shewmr4_1541 glutaredoxin 2 YP_001183158.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_001183159.1 KEGG: shm:Shewmr7_1610 hypothetical protein YP_001183160.1 PFAM: ribosome modulation factor; KEGG: shm:Shewmr7_1611 ribosome modulation factor YP_001183161.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001183162.1 KEGG: shm:Shewmr7_1613 conserved hypothetical ATP-dependent protease YP_001183163.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_001183164.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001183165.1 KEGG: she:Shewmr4_1549 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001183166.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1865 ABC transporter, ATP-binding protein YP_001183167.1 KEGG: son:SO1866 hypothetical protein YP_001183168.1 PFAM: protein of unknown function DUF480; KEGG: son:SO1867 hypothetical protein YP_001183169.1 KEGG: she:Shewmr4_1555 hypothetical protein YP_001183170.1 KEGG: shm:Shewmr7_1631 hypothetical protein YP_001183171.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001183172.1 PFAM: S-adenosylmethionine decarboxylase; KEGG: son:SO1871 S-adenosylmethionine decarboxylase proenzyme, putative YP_001183173.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001183174.1 PFAM: protein of unknown function DUF188; KEGG: she:Shewmr4_1560 protein of unknown function DUF188 YP_001183175.1 PFAM: YceI family protein; KEGG: shm:Shewmr7_1636 YceI family protein YP_001183176.1 KEGG: shm:Shewmr7_1637 hypothetical protein YP_001183177.1 PFAM: peptidase M61 domain protein; KEGG: shm:Shewmr7_2385 peptidase M61 domain protein YP_001183178.1 PFAM: histidine triad (HIT) protein; KEGG: shm:Shewmr7_2384 histidine triad (HIT) protein YP_001183179.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_2383 uncharacterized domain 1 YP_001183180.1 PFAM: protein of unknown function DUF1425; KEGG: son:SO2720 hypothetical protein YP_001183181.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_001183182.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO2718 hypothetical protein YP_001183183.1 PFAM: cyclic nucleotide-binding; KEGG: son:SO2717 cyclic nucleotide binding protein, putative YP_001183184.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO2715 TonB-dependent receptor YP_001183185.1 KEGG: son:SO2714 hypothetical protein YP_001183186.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: shm:Shewmr7_2378 nicotinamide mononucleotide transporter PnuC YP_001183187.1 PFAM: aminoglycoside phosphotransferase; KEGG: son:SO2712 hypothetical protein YP_001183188.1 KEGG: son:SO2711 hypothetical protein YP_001183189.1 PFAM: nitroreductase; KEGG: shm:Shewmr7_2374 nitroreductase YP_001183190.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_2373 GCN5-related N-acetyltransferase YP_001183191.1 KEGG: shm:Shewmr7_2369 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_001183192.1 PFAM: protein of unknown function DUF482; KEGG: son:SO1953 hypothetical protein YP_001183193.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: she:Shewmr4_2295 lysine exporter protein (LysE/YggA) YP_001183194.1 KEGG: son:SO1962 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001183195.1 PFAM: homogentisate 1,2-dioxygenase; KEGG: shm:Shewmr7_2363 homogentisate 1,2-dioxygenase YP_001183196.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO1965 transcriptional regulator, LysR family YP_001183197.1 PFAM: protein of unknown function DUF124; KEGG: she:Shewmr4_2289 protein of unknown function DUF124 YP_001183198.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_2471 TonB-dependent receptor YP_001183199.1 KEGG: son:SO1967 hypothetical protein YP_001183200.1 KEGG: shm:Shewmr7_2360 hypothetical protein YP_001183201.1 PFAM: protein of unknown function DUF55; KEGG: son:SO1969 hypothetical protein YP_001183202.1 KEGG: son:SO1970 hypothetical protein YP_001183203.1 activates fatty acids by binding to coenzyme A YP_001183204.1 KEGG: she:Shewmr4_1565 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein YP_001183205.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_001183206.1 involved in regulation of intracellular pH under alkaline conditions YP_001183207.1 Multifunctional regulator of fatty acid metabolism YP_001183208.1 PFAM: SpoVR family protein; KEGG: son:SO2884 hypothetical protein YP_001183209.1 PFAM: protein of unknown function DUF444; KEGG: shm:Shewmr7_1645 protein of unknown function DUF444 YP_001183210.1 PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: shm:Shewmr7_1646 putative serine protein kinase, PrkA YP_001183211.1 PFAM: manganese and iron superoxide dismutase; KEGG: shm:Shewmr7_1647 superoxide dismutase YP_001183212.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: shm:Shewmr7_1648 glutaredoxin-like protein YP_001183213.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: son:SO2879 uracil permease YP_001183214.1 KEGG: she:Shewmr4_1575 hypothetical protein YP_001183215.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_001183216.1 KEGG: son:SO2876 hypothetical protein YP_001183217.1 KEGG: shm:Shewmr7_2421 hypothetical protein YP_001183218.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: son:SO2871 arsenate reductase, putative YP_001183219.1 PFAM: peptidase M48, Ste24p; Tetratricopeptide TPR_2 repeat protein; KEGG: shm:Shewmr7_2419 peptidase M48, Ste24p YP_001183220.1 PFAM: SirA family protein; KEGG: shm:Shewmr7_2418 SirA family protein YP_001183221.1 PFAM: protein of unknown function UPF0118; KEGG: shm:Shewmr7_2417 protein of unknown function UPF0118 YP_001183222.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001183223.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: son:SO2865 L-lysine exporter, putative YP_001183224.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_001183225.1 KEGG: son:SO1878 glycine cleavage system transcriptional repressor, putative YP_001183226.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001183227.1 PFAM: NlpBDapX family lipoprotein; KEGG: son:SO1880 lipoprotein-34 NlpB YP_001183228.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_2410 efflux transporter, RND family, MFP subunit YP_001183229.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_2409 acriflavin resistance protein YP_001183230.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_2335 GCN5-related N-acetyltransferase YP_001183231.1 PFAM: glucose sorbosone dehydrogenase; KEGG: ilo:IL2579 glucose dehydrogenase, putative YP_001183232.1 PFAM: protein of unknown function DUF81; KEGG: she:Shewmr4_2333 protein of unknown function DUF81 YP_001183233.1 KEGG: shm:Shewmr7_2405 hypothetical protein YP_001183234.1 PFAM: ThiJ/PfpI domain protein; KEGG: son:SO1887 hypothetical protein YP_001183237.1 KEGG: shm:Shewmr7_2400 3-oxoacid CoA-transferase, B subunit; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001183238.1 KEGG: son:SO1892 acetate CoA-transferase, subunit A; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001183239.1 PFAM: pyruvate carboxyltransferase; KEGG: shm:Shewmr7_2398 pyruvate carboxyltransferase YP_001183240.1 PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: son:SO1894 3-methylcrotonyl-CoA carboxylase alpha subunit YP_001183241.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: son:SO1895 enoyl-CoA hydratase YP_001183242.1 PFAM: carboxyl transferase; KEGG: she:Shewmr4_2323 propionyl-CoA carboxylase YP_001183243.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: son:SO1897 isovaleryl-CoA dehydrogenase YP_001183244.1 PFAM: regulatory protein, MerR; KEGG: shm:Shewmr7_2393 transcriptional regulator, MerR family YP_001183245.1 PFAM: AMP-dependent synthetase and ligase; KEGG: she:Shewmr4_2319 AMP-dependent synthetase and ligase YP_001183246.1 PFAM: small multidrug resistance protein; KEGG: son:SO1901 sugE protein YP_001183247.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001183248.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_1689 transcriptional regulator, LysR family YP_001183249.1 PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B; KEGG: shm:Shewmr7_1691 extradiol ring-cleavage dioxygenase, class III enzyme, subunit B YP_001183250.1 TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; KEGG: son:SO1910 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_001183251.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: she:Shewmr4_1618 short-chain dehydrogenase/reductase SDR YP_001183252.1 KEGG: she:Shewmr4_1619 acyl-CoA thioesterase II; TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase YP_001183253.1 KEGG: son:SO1913 hypothetical protein YP_001183254.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_1621 transcriptional regulator, LysR family YP_001183255.1 PFAM: major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_1697 major facilitator superfamily MFS_1 YP_001183256.1 PFAM: Ppx/GppA phosphatase; KEGG: she:Shewmr4_2208 Ppx/GppA phosphatase YP_001183257.1 PFAM: Polyphosphate kinase; KEGG: she:Shewmr4_2207 polyphosphate kinase YP_001183258.1 KEGG: she:Shewmr4_2206 hypothetical protein YP_001183259.1 PFAM: CreA family protein; KEGG: she:Shewmr4_2205 CreA family protein YP_001183260.1 catalyzes the formation of L-homocysteine from cystathionine YP_001183261.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: shm:Shewmr7_2280 periplasmic sensor signal transduction histidine kinase YP_001183262.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO2193 DNA-binding response regulator YP_001183263.1 KEGG: shm:Shewmr7_2277 vault protein inter-alpha-trypsin domain protein; TIGRFAM: LPXTG-motif cell wall anchor domain; PFAM: von Willebrand factor, type A; Vault protein inter-alpha-trypsin domain protein; SMART: Vault protein inter-alpha-trypsin, metazoa YP_001183264.1 TIGRFAM: sortase family protein; PFAM: peptidase C60, sortase A and B; KEGG: she:Shewmr4_2199 sortase family protein YP_001183265.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: she:Shewmr4_2198 diguanylate cyclase YP_001183266.1 PFAM: peptidase M28; KEGG: she:Shewmr4_2197 peptidase M28 YP_001183267.1 KEGG: shm:Shewmr7_2273 hypothetical protein YP_001183268.1 TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: son:SO2200 ribosomal protein S6 modification protein, putative YP_001183269.1 PFAM: protein of unknown function DUF413; KEGG: she:Shewmr4_2194 protein of unknown function DUF413 YP_001183270.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2202 transcriptional regulator, LysR family YP_001183271.1 PFAM: diacylglycerol kinase; KEGG: shm:Shewmr7_2269 diacylglycerol kinase YP_001183272.1 catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_001183273.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: she:Shewmr4_2189 protein tyrosine phosphatase YP_001183274.1 KEGG: shm:Shewmr7_3172 hypothetical protein YP_001183275.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ppr:PBPRB1061 hypothetical protein YP_001183276.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_001183277.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: shm:Shewmr7_2262 2OG-Fe(II) oxygenase YP_001183278.1 this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae YP_001183279.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001183280.1 PFAM: peptidase M22, glycoprotease; KEGG: son:SO2586 hypothetical protein YP_001183281.1 KEGG: shm:Shewmr7_2258 hypothetical protein YP_001183282.1 KEGG: she:Shewmr4_2180 hypothetical protein YP_001183283.1 KEGG: shm:Shewmr7_2256 hypothetical protein YP_001183284.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: shm:Shewmr7_2255 alpha/beta hydrolase fold YP_001183285.1 Activates fatty acids by binding to coenzyme A YP_001183286.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: she:Shewmr4_2176 ribonuclease D YP_001183287.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001183288.1 TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: shm:Shewmr7_2251 septum site-determining protein MinD YP_001183289.1 blocks the formation of polar Z-ring septums YP_001183290.1 PFAM: protein of unknown function DUF709; KEGG: son:SO2575 hypothetical protein YP_001183291.1 PFAM: protein of unknown function UPF0153; KEGG: she:Shewmr4_2170 protein of unknown function UPF0153 YP_001183292.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: she:Shewmr4_2169 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001183293.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO2571 ATP-dependent RNA helicase, DEAD box family YP_001183294.1 PFAM: protein of unknown function DUF885; KEGG: son:SO2570 lipoprotein, putative YP_001183295.1 KEGG: son:SO2569 hypothetical protein YP_001183296.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001183297.1 PFAM: AsmA family protein; KEGG: shm:Shewmr7_2241 AsmA family protein YP_001183298.1 KEGG: shm:Shewmr7_2240 intracellular proteinase inhibitor domain protein YP_001183299.1 PFAM: Peptidoglycan-binding LysM; Lytic transglycosylase, catalytic; MLTD_N domain protein; KEGG: shm:Shewmr7_2239 MLTD_N domain protein YP_001183300.1 PFAM: beta-lactamase domain protein; KEGG: shm:Shewmr7_2238 hydroxyacylglutathione hydrolase YP_001183301.1 PFAM: Methyltransferase type 11; KEGG: she:Shewmr4_2160 methyltransferase type 11 YP_001183302.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2236 transcriptional regulator, LysR family YP_001183303.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001183304.1 KEGG: son:SO2559 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_001183305.1 KEGG: shm:Shewmr7_2233 hypothetical protein YP_001183306.1 PFAM: OmpA/MotB domain protein; KEGG: noc:Noc_2042 OmpA/MotB YP_001183307.1 KEGG: son:SO2554 hypothetical protein YP_001183308.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria; KEGG: son:SO2553 hyperosmotically inducible periplasmic protein YP_001183309.1 KEGG: son:SO2552 hypothetical protein YP_001183310.1 PFAM: cyclic nucleotide-binding; KEGG: son:SO2551 transcriptional regulator-related protein YP_001183311.1 KEGG: son:SO2550 transcriptional regulator-related protein YP_001183312.1 PFAM: transport-associated; KEGG: son:SO2549 hypothetical protein YP_001183313.1 KEGG: rfr:Rfer_1879 hypothetical protein YP_001183314.1 PFAM: PRC-barrel domain protein; KEGG: net:Neut_2352 PRC-barrel domain protein YP_001183315.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001183316.1 PFAM: glutamine amidotransferase, class-II; KEGG: shm:Shewmr7_2222 glutamine amidotransferase, class-II YP_001183317.1 KEGG: son:SO2533 hypothetical protein YP_001183318.1 PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase; KEGG: shm:Shewmr7_2220 methylated-DNA-(protein)-cysteine S-methyltransferase YP_001183319.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001183320.1 KEGG: shm:Shewmr7_2218 hypothetical protein YP_001183321.1 KEGG: cgb:cg2479 hypothetical protein YP_001183322.1 PFAM: Fmu (Sun) domain protein; KEGG: she:Shewmr4_2131 Fmu (Sun) domain protein YP_001183323.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; PAS fold domain protein; KEGG: she:Shewmr4_2130 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) YP_001183324.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001183325.1 SMART: extracellular solute-binding protein, family 3; KEGG: dvu:DVU0852 extracellular solute-binding protein, putative YP_001183326.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001183327.1 KEGG: shm:Shewmr7_2203 hypothetical protein YP_001183328.1 PFAM: NUDIX hydrolase; KEGG: she:Shewmr4_2126 NUDIX hydrolase YP_001183329.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein; KEGG: son:SO2221 para-aminobenzoate synthase, component I YP_001183330.1 TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; Fe-S type hydro-lyases tartrate/fumarate beta region; KEGG: son:SO2222 fumarate hydratase, class I, anaerobic, putative YP_001183331.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: shm:Shewmr7_2199 peptidase S9, prolyl oligopeptidase active site domain protein YP_001183332.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_2122 GCN5-related N-acetyltransferase YP_001183333.1 KEGG: she:Shewmr4_2121 hypothetical protein YP_001183334.1 PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: she:Shewmr4_1683 iron-containing alcohol dehydrogenase YP_001183335.1 PFAM: multiple antibiotic resistance (MarC)-related proteins; KEGG: son:SO2137 multiple antibiotic resistance protein YP_001183336.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Nitrate and nitrite sensing domain protein; KEGG: shm:Shewmr7_1760 methyl-accepting chemotaxis sensory transducer YP_001183337.1 PFAM: major facilitator superfamily MFS_1; KEGG: bur:Bcep18194_A4906 major facilitator superfamily (MFS_1) transporter YP_001183338.1 PFAM: major facilitator superfamily MFS_1; KEGG: pfl:PFL_3980 major facilitator family transporter YP_001183339.1 PFAM: beta-lactamase; KEGG: pae:PA2315 hypothetical protein YP_001183340.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: pae:PA2316 probable transcriptional regulator YP_001183341.1 TIGRFAM: CRISPR-associated protein Cas1; KEGG: ppr:PBPRB1995 hypothetical protein YP_001183342.1 SMART: DEAD-like helicases-like; KEGG: ppr:PBPRB1994 hypothetical protein YP_001183343.1 KEGG: ppr:PBPRB1993 hypothetical protein YP_001183344.1 KEGG: ppr:PBPRB1992 hypothetical protein YP_001183345.1 TIGRFAM: CRISPR-associated protein, Csy4 family; KEGG: ppr:PBPRB1991 hypothetical protein YP_001183346.1 SMART: helicase c2; KEGG: shm:Shewmr7_2172 helicase C2 YP_001183347.1 KEGG: shm:Shewmr7_2388 cytochrome c3 YP_001183348.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_1806 TonB-dependent receptor YP_001183349.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_2170 methyl-accepting chemotaxis sensory transducer YP_001183350.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001183351.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001183352.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001183353.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_001183354.1 TIGRFAM: hydrogenase nickel insertion protein HypA; PFAM: hydrogenase expression/synthesis, HypA; KEGG: shm:Shewmr7_2165 hydrogenase nickel insertion protein HypA YP_001183355.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: shm:Shewmr7_2164 hydrogenase expression/formation protein HypE YP_001183356.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: son:SO2091 hydrogenase expression/formation protein HypD YP_001183357.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: son:SO2092 hydrogenase assembly chaperone hypC/hupF YP_001183358.1 TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K; KEGG: son:SO2093 hydrogenase accessory protein HypB YP_001183359.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: she:Shewmr4_2098 CoA-binding domain protein YP_001183360.1 KEGG: pfl:PFL_3338 hypothetical protein YP_001183361.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO2525 ABC transporter, ATP-binding protein YP_001183362.1 KEGG: shm:Shewmr7_1896 hypothetical protein YP_001183363.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: ilo:IL2511 outer membrane receptor for ferric siderophore YP_001183364.1 PFAM: Propeptide, PepSY amd peptidase M4; PepSY-associated TM helix domain protein; KEGG: shm:Shewmr7_1899 PepSY-associated TM helix domain protein YP_001183365.1 KEGG: she:Shewmr4_2075 hypothetical protein YP_001183366.1 KEGG: she:Shewmr4_2070 endonuclease III; TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_001183367.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_001183368.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_001183369.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_001183370.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001183371.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001183372.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: shm:Shewmr7_1911 electron transport complex, RnfABCDGE type, A subunit YP_001183373.1 PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: shm:Shewmr7_1912 diguanylate cyclase/phosphodiesterase YP_001183374.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001183375.1 PFAM: Rhomboid family protein; KEGG: she:Shewmr4_2060 rhomboid family protein YP_001183376.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_001183377.1 KEGG: son:SO2501 radical activating enzyme YP_001183378.1 KEGG: she:Shewmr4_2057 hypothetical protein YP_001183379.1 KEGG: son:SO2499 hypothetical protein YP_001183380.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; PAS fold domain protein; KEGG: she:Shewmr4_2055 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) YP_001183381.1 PFAM: SEC-C motif domain protein; KEGG: shm:Shewmr7_1921 sec-C motif domain protein YP_001183382.1 KEGG: she:Shewmr4_2053 hypothetical protein YP_001183383.1 PFAM: Smr protein/MutS2; KEGG: she:Shewmr4_2052 Smr protein/MutS2 YP_001183384.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_1925 transcriptional regulator, TetR family YP_001183385.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001183386.1 PFAM: pyruvate kinase; KEGG: shm:Shewmr7_1927 pyruvate kinase YP_001183387.1 Represses the expression of the zwf, eda, glp and gap YP_001183388.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001183389.1 TIGRFAM: 6-phosphogluconolactonase; KEGG: son:SO2488 6-phosphogluconolactonase YP_001183390.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001183391.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001183392.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_001183393.1 KEGG: shm:Shewmr7_1934 metal dependent phosphohydrolase YP_001183394.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001183395.1 PFAM: Na+/H+ antiporter NhaC; KEGG: shm:Shewmr7_1936 Na+/H+ antiporter NhaC YP_001183396.1 KEGG: she:Shewmr4_1801 hypothetical protein YP_001183397.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001183398.1 KEGG: shm:Shewmr7_1938 hypothetical protein YP_001183399.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001183400.1 KEGG: shm:Shewmr7_1940 CopG domain protein DNA-binding domain protein YP_001183401.1 KEGG: shm:Shewmr7_1941 hypothetical protein YP_001183402.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: shm:Shewmr7_1942 alpha/beta hydrolase fold YP_001183403.1 negative modulator of the initiation of chromosome replication YP_001183404.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001183405.1 KEGG: son:SO2337 peptide methionine sulfoxide reductase; TIGRFAM: peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A YP_001183406.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_001183407.1 PFAM: dehydrogenase, E1 component; KEGG: shm:Shewmr7_1947 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) YP_001183408.1 PFAM: Transketolase, central region; Transketolase domain protein; KEGG: shm:Shewmr7_1948 transketolase, central region YP_001183409.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: shm:Shewmr7_1949 catalytic domain of components of various dehydrogenase complexes YP_001183410.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001183411.1 KEGG: son:SO2345 glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001183412.1 KEGG: she:Shewmr4_2022 hypothetical protein YP_001183413.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent YP_001183414.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: son:SO2109 hypothetical protein YP_001183415.1 PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: son:SO2110 hypothetical protein YP_001183416.1 KEGG: son:SO2111 hypothetical protein YP_001183417.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001183418.1 PFAM: protein of unknown function DUF490; KEGG: she:Shewmr4_1835 protein of unknown function DUF490 YP_001183419.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: son:SO2114 hypothetical protein YP_001183420.1 PFAM: peptidase T2, asparaginase 2; KEGG: shm:Shewmr7_2140 peptidase T2, asparaginase 2 YP_001183421.1 PFAM: CBS domain containing protein; KEGG: shm:Shewmr7_2139 putative signal transduction protein with CBS domains YP_001183422.1 KEGG: shm:Shewmr7_2138 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD-like helicases-like YP_001183423.1 PFAM: periplasmic nitrate reductase NapE; KEGG: shm:Shewmr7_2137 periplasmic nitrate reductase NapE YP_001183424.1 PFAM: NapD family protein; KEGG: shm:Shewmr7_2136 NapD family protein YP_001183425.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001183426.1 PFAM: Nitrate reductase cytochrome c-type subunit (NapB); KEGG: she:Shewmr4_1843 nitrate reductase cytochrome c-type subunit (NapB) YP_001183427.1 TIGRFAM: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family; PFAM: NapC/NirT cytochrome c domain protein; KEGG: shm:Shewmr7_2133 periplasmic nitrate (or nitrite) reductase C-type cytochrome, NapC/NirT family YP_001183428.1 KEGG: rba:RB11509 hypothetical protein YP_001183429.1 KEGG: son:SO2234 hypothetical protein YP_001183430.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji, jmjC domain protein; KEGG: cps:CPS_2133 hypothetical protein YP_001183431.1 PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: shm:Shewmr7_2111 sodium/sulphate symporter YP_001183432.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: shm:Shewmr7_2110 transcriptional regulator, AraC family YP_001183433.1 PFAM: YCII-related; KEGG: son:SO2457 hypothetical protein YP_001183434.1 KEGG: son:SO2451 hypothetical protein YP_001183435.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: shm:Shewmr7_2104 alkylhydroperoxidase like protein, AhpD family YP_001183436.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: she:Shewmr4_1875 transcriptional regulator, AraC family YP_001183437.1 PFAM: UspA domain protein; KEGG: sfr:Sfri_2734 hypothetical protein YP_001183438.1 KEGG: son:SO2449 hypothetical protein YP_001183439.1 KEGG: cvi:CV2953 hypothetical protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001183440.1 PFAM: NUDIX hydrolase; KEGG: son:SO2448 MutT/nudix family protein YP_001183441.1 PFAM: DTW domain containing protein; KEGG: sfr:Sfri_1306 DTW domain containing protein YP_001183442.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: she:Shewmr4_1879 channel protein, hemolysin III family YP_001183443.1 KEGG: son:SO2446 hypothetical protein YP_001183444.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001183445.1 KEGG: shm:Shewmr7_2096 thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1 YP_001183446.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: she:Shewmr4_1883 UBA/ThiF-type NAD/FAD binding protein YP_001183447.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: son:SO2442 thiS protein, putative YP_001183448.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001183449.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_001183450.1 KEGG: son:SO2439.2 hypothetical methyl-accepting chemotaxis protein YP_001183451.1 KEGG: she:Shewmr4_1888 SrpA-related protein YP_001183452.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO2438 transcriptional regulator, LysR family YP_001183453.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: shm:Shewmr7_2087 hypothetical protein YP_001183454.1 TIGRFAM: putative methyltransferase; PFAM: methyltransferase, putative; Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_2083 putative methyltransferase YP_001183455.1 TIGRFAM: putative methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: she:Shewmr4_1896 putative methyltransferase YP_001183456.1 KEGG: she:Shewmr4_1897 diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: extracellular solute-binding protein, family 3 YP_001183457.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001183458.1 PFAM: protein of unknown function DUF28; KEGG: shm:Shewmr7_2079 protein of unknown function DUF28 YP_001183459.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001183460.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001183461.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001183462.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_1903 TonB-dependent receptor YP_001183463.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO2426 DNA-binding response regulator YP_001183464.1 PFAM: peptidase M14, carboxypeptidase A; KEGG: shm:Shewmr7_2073 peptidase M14, carboxypeptidase A YP_001183465.1 KEGG: shm:Shewmr7_2072 hypothetical protein YP_001183466.1 PFAM: protein of unknown function DUF1315; KEGG: son:SO2422 hypothetical protein YP_001183467.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001183468.1 PFAM: protein of unknown function UPF0052 and CofD; KEGG: shm:Shewmr7_1956 hypothetical protein YP_001183469.1 KEGG: she:Shewmr4_2018 bax protein, putative YP_001183470.1 KEGG: son:SO2353 hypothetical protein YP_001183471.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001183472.1 with UspC and UspD is involved in resistance to UV irradiation YP_001183473.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_001183474.1 KEGG: son:SO2357 hypothetical protein YP_001183475.1 TIGRFAM: cytochrome oxidase maturation protein, cbb3-type; PFAM: cytochrome oxidase maturation protein cbb3-type; KEGG: shm:Shewmr7_1963 cytochrome oxidase maturation protein, cbb3-type YP_001183476.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: she:Shewmr4_2011 heavy metal translocating P-type ATPase YP_001183477.1 KEGG: son:SO2360 hypothetical protein YP_001183478.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III; PFAM: cytochrome c, class I; KEGG: shm:Shewmr7_1966 cytochrome c oxidase, cbb3-type, subunit III YP_001183479.1 PFAM: Cbb3-type cytochrome oxidase component; KEGG: shm:Shewmr7_1967 Cbb3-type cytochrome oxidase component YP_001183480.1 CcoO; FixO YP_001183481.1 CcoN; FixN YP_001183482.1 KEGG: son:SO2365 hypothetical protein YP_001183483.1 PFAM: transposase Tn3 family protein; KEGG: sfr:Sfri_3470 transposase Tn3 family protein YP_001183484.1 PFAM: transposase IS3/IS911 family protein; KEGG: vpa:VP1788 putative transposase YP_001183485.1 PFAM: Integrase, catalytic region; KEGG: vpa:VP1787 putative transposase YP_001183486.1 PFAM: Bile acid:sodium symporter; KEGG: dar:Daro_2614 putative efflux protein YP_001183487.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: chu:CHU_1510 cation-transporting ATPase; possible zinc-transporting ATPase YP_001183489.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: sde:Sde_1955 cation efflux system protein YP_001183490.1 PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: sde:Sde_1956 hypothetical protein YP_001183491.1 PFAM: outer membrane efflux protein; KEGG: sde:Sde_1958 aconitate hydratase 1 YP_001183493.1 KEGG: abo:ABO_1368 cation efflux system permease, putative YP_001183494.1 TIGRFAM: Cd(II)/Pb(II)-responsive transcriptional regulator; PFAM: regulatory protein, MerR; KEGG: sde:Sde_1961 putative transcriptional regulator, MerR family YP_001183495.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: tcx:Tcr_1429 cation diffusion facilitator family transporter YP_001183496.1 PFAM: protein of unknown function UPF0060; KEGG: abo:ABO_1373 hypothetical protein YP_001183498.1 PFAM: sulfatase; protein of unknown function DUF1705; KEGG: ilo:IL1649 membrane hydrolase of alkaline phosphatase superfamily YP_001183499.1 PFAM: sulfatase; KEGG: mfa:Mfla_1399 sulfatase YP_001183500.1 PFAM: diacylglycerol kinase; KEGG: sdy:SDY_4532 diacylglycerol kinase YP_001183501.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ilo:IL1648 response regulator (CheY, wHTH domains) YP_001183502.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: ilo:IL1647 signal transduction histidine kinase YP_001183503.1 PFAM: Bile acid:sodium symporter; KEGG: dar:Daro_2614 putative efflux protein YP_001183504.1 KEGG: psp:PSPPH_2263 cointegrate resolution protein T YP_001183505.1 KEGG: vch:VCA0486 hypothetical protein YP_001183506.1 KEGG: vch:VCA0487 hypothetical protein YP_001183507.1 PFAM: phage integrase family protein; KEGG: pfo:Pfl_2926 phage integrase YP_001183508.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: shm:Shewmr7_1971 response regulator receiver modulated metal dependent phosphohydrolase YP_001183509.1 PFAM: transposase Tn3 family protein; KEGG: sfr:Sfri_3470 transposase Tn3 family protein YP_001183510.1 PFAM: plasmid stabilization system; KEGG: sfr:Sfri_3471 plasmid stabilization system YP_001183511.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: sfr:Sfri_3472 prevent-host-death family protein YP_001183512.1 PFAM: Resolvase, N-terminal domain; KEGG: sfr:Sfri_3477 resolvase, N-terminal domain protein YP_001183513.1 KEGG: sil:SPO2248 DnaK suppressor protein, putative YP_001183514.1 PFAM: UspA domain protein; KEGG: sfr:Sfri_0791 UspA domain protein YP_001183515.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sfr:Sfri_0790 sulphate transporter YP_001183516.1 KEGG: shm:Shewmr7_1971 response regulator receiver modulated metal dependent phosphohydrolase YP_001183517.1 KEGG: shm:Shewmr7_1972 hypothetical protein YP_001183519.1 uncharacterized member of the major facilitator superfamily (MFS) YP_001183520.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_1974 transcriptional regulator, LysR family YP_001183521.1 PFAM: protein of unknown function UPF0005; KEGG: son:SO2375 membrane protein, putative YP_001183522.1 PFAM: DsrE family protein; KEGG: shm:Shewmr7_2004 DsrE family protein YP_001183523.1 PFAM: DsrE family protein; KEGG: shm:Shewmr7_2005 DsrE family protein YP_001183524.1 PFAM: DsrH family protein; KEGG: son:SO2378 putative uncharacterized protein involved in oxidation of intracellular sulfur YP_001183525.1 PFAM: DsrC family protein; KEGG: she:Shewmr4_1969 DsrC family protein YP_001183526.1 KEGG: shm:Shewmr7_2008 hypothetical protein YP_001183527.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001183528.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001183529.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: son:SO2308 ATPase, AAA family YP_001183530.1 PFAM: outer membrane lipoprotein carrier protein LolA; KEGG: shm:Shewmr7_2012 outer membrane lipoprotein carrier protein LolA YP_001183531.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: shm:Shewmr7_2013 cell divisionFtsK/SpoIIIE YP_001183532.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_001183533.1 TIGRFAM: alanine dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Shikimate/quinate 5-dehydrogenase; alanine dehydrogenase/PNT domain protein; KEGG: shm:Shewmr7_2015 alanine dehydrogenase YP_001183534.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO2303 thioredoxin reductase YP_001183535.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001183536.1 PFAM: ribosomal protein L35; KEGG: sfr:Sfri_2026 ribosomal protein L35 YP_001183537.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001183538.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001183539.1 KEGG: shm:Shewmr7_2023 hypothetical protein YP_001183540.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001183541.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: shm:Shewmr7_2025 MATE efflux family protein YP_001183543.1 serine protease inhibitor, inhibits trypsin and other proteases YP_001183544.1 KEGG: vfi:VF0709 hypothetical protein YP_001183545.1 KEGG: shm:Shewmr7_2030 ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001183546.1 KEGG: she:Shewmr4_1945 hypothetical protein YP_001183547.1 PFAM: protein of unknown function DUF839; KEGG: shm:Shewmr7_2034 twin-arginine translocation pathway signal YP_001183548.1 PFAM: DTW domain containing protein; KEGG: son:SO2387 conserved hypothetical protein YP_001183549.1 PFAM: beta-lactamase; KEGG: shm:Shewmr7_2039 beta-lactamase YP_001183550.1 multidrug efflux protein involved in adaptation to low energy shock YP_001183551.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_001183552.1 KEGG: shm:Shewmr7_2042 hypothetical protein YP_001183553.1 KEGG: shm:Shewmr7_2043 hypothetical protein YP_001183554.1 KEGG: shm:Shewmr7_2044 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C YP_001183555.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: she:Shewmr4_1931 acyl-CoA dehydrogenase domain protein YP_001183556.1 KEGG: she:Shewmr4_1930 hypothetical protein YP_001183557.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: shm:Shewmr7_2049 short-chain dehydrogenase/reductase SDR YP_001183558.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001183559.1 KEGG: son:SO2399 hypothetical protein YP_001183560.1 PFAM: protein of unknown function DUF1049; KEGG: shm:Shewmr7_2052 protein of unknown function DUF1049 YP_001183561.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001183562.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001183563.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001183564.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001183565.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001183566.1 PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: shm:Shewmr7_1974 SMP-30/gluconolaconase/LRE domain protein YP_001183567.1 PFAM: glycoside hydrolase, family 43; KEGG: she:Shewmr4_1999 glycoside hydrolase, family 43 YP_001183568.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_1977 TonB-dependent receptor YP_001183569.1 PFAM: protein of unknown function DUF81; KEGG: she:Shewmr4_1997 protein of unknown function DUF81 YP_001183570.1 PFAM: glycoside hydrolase, family 43; KEGG: she:Shewmr4_1996 glycoside hydrolase, family 43 YP_001183571.1 PFAM: glycoside hydrolase, family 43; KEGG: shm:Shewmr7_1980 arabinan endo-1,5-alpha-L-arabinosidase YP_001183572.1 TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_1994 sugar (glycoside-pentoside-hexuronide) transporter YP_001183573.1 PFAM: glycoside hydrolase, family 43; KEGG: sde:Sde_0777 ribosomal protein L11 methyltransferase YP_001183574.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: pfl:PFL_1735 methyl-accepting chemotaxis protein YP_001183575.1 PFAM: glycoside hydrolase, family 43; KEGG: shm:Shewmr7_1984 alpha-N-arabinofuranosidase YP_001183576.1 membrane component of a putative sugar ABC transporter system YP_001183577.1 PFAM: inner-membrane translocator; KEGG: shm:Shewmr7_1986 inner-membrane translocator YP_001183578.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_1987 ABC transporter related YP_001183579.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: shm:Shewmr7_1988 periplasmic binding protein/LacI transcriptional regulator YP_001183580.1 PFAM: Aldose 1-epimerase; KEGG: shm:Shewmr7_1989 aldose 1-epimerase YP_001183581.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: she:Shewmr4_1984 short-chain dehydrogenase/reductase SDR YP_001183582.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_001183583.1 PFAM: glycoside hydrolase, family 43; KEGG: she:Shewmr4_1982 glycoside hydrolase, family 43 YP_001183584.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: shm:Shewmr7_1993 GntR domain protein YP_001183585.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; beta-phosphoglucomutase family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_1994 HAD-superfamily hydrolase, subfamily IA, variant 3 YP_001183586.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_001183587.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001183588.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_001183589.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001183590.1 TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal repeat, beta-propeller; KEGG: she:Shewmr4_1919 DNA gyrase, A subunit YP_001183591.1 Involved in ubiquinone biosynthesis YP_001183592.1 KEGG: shm:Shewmr7_2061 HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001183593.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001183594.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_001183595.1 PFAM: ferredoxin; KEGG: shm:Shewmr7_2064 ferredoxin YP_001183596.1 KEGG: hne:HNE_0837 YCII domain protein YP_001183597.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_1910 NADH:flavin oxidoreductase/NADH oxidase YP_001183598.1 TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; KEGG: she:Shewmr4_1909 signal peptide peptidase SppA, 67K type YP_001183599.1 converts asparagine to aspartate and ammonia YP_001183600.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_001183601.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_001183602.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO2105 sensor protein YgiY, putative YP_001183603.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO2104 DNA-binding response regulator YgiX, putative YP_001183604.1 PFAM: ApbE family lipoprotein; KEGG: shm:Shewmr7_2151 ApbE family lipoprotein YP_001183605.1 KEGG: shm:Shewmr7_2152 hypothetical protein YP_001183606.1 KEGG: shm:Shewmr7_2153 lipoprotein, putative YP_001183607.1 PFAM: Redoxin domain protein; KEGG: shm:Shewmr7_2154 redoxin domain protein YP_001183608.1 KEGG: son:SO2099 hydrogenase small chain; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Nickel-iron dehydrogenase small subunit, N-terminal domain protein YP_001183609.1 PFAM: nickel-dependent hydrogenase, large subunit; KEGG: son:SO2098 hydrogenase large chain YP_001183610.1 TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: shm:Shewmr7_2157 Ni/Fe-hydrogenase, b-type cytochrome subunit YP_001183611.1 TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; PFAM: peptidase M52, hydrogen uptake protein; KEGG: son:SO2096 hydrogenase expression/formation protein YP_001183612.1 KEGG: son:SO2095 hypothetical protein YP_001183613.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC, N-terminal domain; zinc finger, HypF domain protein; KEGG: son:SO2094 hydrogenase maturation protein HypF YP_001183614.1 PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: pat:Patl_2284 sodium/hydrogen exchanger YP_001183615.1 PFAM: UspA domain protein; KEGG: pat:Patl_2285 UspA YP_001183616.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_1872 diguanylate cyclase YP_001183617.1 PFAM: sulfatase; protein of unknown function DUF1705; KEGG: she:Shewmr4_2103 sulfatase YP_001183618.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller; KEGG: son:SO2047 prolyl oligopeptidase family protein YP_001183619.1 PFAM: regulatory protein, MarR; KEGG: shm:Shewmr7_1869 transcriptional regulator, MarR family YP_001183620.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: shm:Shewmr7_1868 cation diffusion facilitator family transporter YP_001183621.1 KEGG: son:SO2044 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001183622.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001183623.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001183624.1 PFAM: protein of unknown function DUF195; KEGG: son:SO2041 hypothetical protein YP_001183625.1 PFAM: Lytic transglycosylase, catalytic; KEGG: shm:Shewmr7_1863 lytic transglycosylase, catalytic YP_001183626.1 PFAM: EAL domain protein; KEGG: she:Shewmr4_2112 diguanylate phosphodiesterase YP_001183627.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; KEGG: son:SO2153 MoxR protein YP_001183628.1 PFAM: protein of unknown function DUF58; KEGG: shm:Shewmr7_1855 protein of unknown function DUF58 YP_001183629.1 PFAM: transglutaminase domain protein; KEGG: son:SO2150 transglutaminase family protein YP_001183630.1 TIGRFAM: exodeoxyribonuclease V, gamma subunit; PFAM: Exodeoxyribonuclease V, RecC subunit; KEGG: she:Shewmr4_1775 exodeoxyribonuclease V, gamma subunit YP_001183631.1 TIGRFAM: exodeoxyribonuclease V, beta subunit; PFAM: UvrD/REP helicase; KEGG: shm:Shewmr7_1852 exodeoxyribonuclease V, beta subunit YP_001183632.1 KEGG: shm:Shewmr7_1851 exodeoxyribonuclease V, alpha subunit; TIGRFAM: exodeoxyribonuclease V, alpha subunit; SMART: AAA ATPase YP_001183633.1 KEGG: son:SO2146 hypothetical protein YP_001183634.1 KEGG: son:SO2245 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_001183635.1 KEGG: son:SO2241 hypothetical protein YP_001183636.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: shm:Shewmr7_1845 methyl-accepting chemotaxis sensory transducer YP_001183637.1 KEGG: shm:Shewmr7_1844 hypothetical protein YP_001183638.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: son:SO2238 phosphocarrier protein HPr YP_001183639.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein; KEGG: she:Shewmr4_1764 phosphoenolpyruvate-protein phosphotransferase YP_001183640.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_001183641.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; methyl-accepting chemotaxis protein domain protein; KEGG: vvu:VV21623 methyl-accepting chemotaxis protein YP_001183642.1 PFAM: arsenate reductase and related; KEGG: shm:Shewmr7_2120 hypothetical protein YP_001183643.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001183644.1 PFAM: peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins; KEGG: son:SO2472 D-alanyl-D-alanine carboxypeptidase-related protein YP_001183645.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO2473 hydrolase, alpha/beta fold family YP_001183646.1 PFAM: carbonic anhydrase; KEGG: she:Shewmr4_1854 carbonate dehydratase YP_001183647.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001183648.1 KEGG: son:SO2479 hypothetical protein YP_001183649.1 KEGG: shm:Shewmr7_1839 hypothetical protein YP_001183650.1 PFAM: Rhodanese domain protein; KEGG: she:Shewmr4_1760 rhodanese domain protein YP_001183651.1 KEGG: shm:Shewmr7_1836 hypothetical protein YP_001183652.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; sulphate transporter; KEGG: she:Shewmr4_1755 sulphate transporter YP_001183653.1 KEGG: shm:Shewmr7_1834 lysine exporter protein (LysE/YggA) YP_001183654.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: she:Shewmr4_1753 transcriptional regulator, GntR family YP_001183655.1 KEGG: she:Shewmr4_1752 alkaline phosphatase YP_001183656.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_1751 drug resistance transporter, Bcr/CflA subfamily YP_001183658.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: she:Shewmr4_1750 acetolactate synthase, large subunit, biosynthetic type YP_001183659.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001183660.1 PFAM: heat shock protein Hsp20; KEGG: son:SO2277 16 kDa heat shock protein A YP_001183661.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001183662.1 PFAM: protein of unknown function DUF528; KEGG: shm:Shewmr7_1826 protein of unknown function DUF528 YP_001183663.1 TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: shm:Shewmr7_1825 alpha-L-glutamate ligases, RimK family YP_001183664.1 TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: shm:Shewmr7_1824 ferredoxin, 2Fe-2S type, ISC system YP_001183665.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_001183666.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_001183667.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; iron-sulfur cluster assembly protein IscA; PFAM: HesB/YadR/YfhF-family protein; KEGG: shm:Shewmr7_1821 iron-sulfur cluster assembly protein IscA YP_001183668.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: shm:Shewmr7_1820 FeS cluster assembly scaffold IscU YP_001183669.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_001183670.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; iron-sulfur cluster assembly transcription factor IscR; PFAM: protein of unknown function UPF0074; KEGG: son:SO2263 Rrf2 family protein YP_001183671.1 TIGRFAM: serine O-acetyltransferase; KEGG: shm:Shewmr7_1817 serine O-acetyltransferase YP_001183672.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: son:SO2261 RNA methyltransferase, TrmH family, group 1 YP_001183673.1 PFAM: inositol monophosphatase; KEGG: shm:Shewmr7_1815 inositol-phosphate phosphatase YP_001183674.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: she:Shewmr4_1734 lipoprotein releasing system, transmembrane protein, LolC/E family YP_001183675.1 KEGG: shm:Shewmr7_1813 lipoprotein releasing system, ATP-binding protein; TIGRFAM: lipoprotein releasing system, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase YP_001183676.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: shm:Shewmr7_1812 lipoprotein releasing system, transmembrane protein, LolC/E family YP_001183677.1 KEGG: son:SO2256 hypothetical protein YP_001183678.1 KEGG: shm:Shewmr7_1810 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001183679.1 KEGG: son:SO2254 hypothetical protein YP_001183680.1 catalyzes the hydrolysis of acylphosphate YP_001183681.1 KEGG: son:SO1425 hypothetical protein YP_001183682.1 KEGG: son:SO1424 hypothetical protein YP_001183683.1 KEGG: son:SO2209 hypothetical protein YP_001183684.1 PFAM: phage integrase family protein; KEGG: shm:Shewmr7_3899 phage integrase family protein YP_001183685.1 TIGRFAM: YD repeat protein; PFAM: Fibronectin, type III domain protein; YD repeat-containing protein; FG-GAP repeat protein; KEGG: shm:Shewmr7_1124 YD repeat protein YP_001183687.1 TIGRFAM: YD repeat protein; KEGG: shm:Shewmr7_1180 YD repeat protein YP_001183689.1 PFAM: protein of unknown function UPF0227; KEGG: son:SO2251 conserved hypothetical protein YP_001183690.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_001183691.1 KEGG: shm:Shewmr7_1804 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001183692.1 KEGG: son:SO2247 hypothetical protein YP_001183693.1 PFAM: putative esterase; KEGG: shm:Shewmr7_2190 carboxylesterase YP_001183694.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: shm:Shewmr7_2191 alcohol dehydrogenase, zinc-binding domain protein YP_001183695.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2192 transcriptional regulator, LysR family YP_001183696.1 PFAM: FAD dependent oxidoreductase; KEGG: shm:Shewmr7_2193 FAD dependent oxidoreductase YP_001183697.1 PFAM: protein of unknown function DUF938; KEGG: son:SO2050 hypothetical protein YP_001183698.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_001183699.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001183700.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001183701.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_001183702.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001183703.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001183704.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001183705.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_001183706.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter, transmembrane; KEGG: she:Shewmr4_1792 aromatic amino acid transporter YP_001183707.1 KEGG: she:Shewmr4_1791 hypothetical protein YP_001183708.1 KEGG: son:SO2063 hypothetical protein YP_001183709.1 PFAM: Uncharacterized conserved protein UCP025560; KEGG: shm:Shewmr7_2188 uncharacterized conserved protein UCP025560 YP_001183712.1 KEGG: vpa:VP1842 RelB protein YP_001183713.1 PFAM: protein of unknown function DUF1379; KEGG: she:Shewmr4_1682 protein of unknown function DUF1379 YP_001183714.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001183715.1 PFAM: NAD-glutamate dehydrogenase; KEGG: shm:Shewmr7_1755 NAD-glutamate dehydrogenase YP_001183716.1 KEGG: shm:Shewmr7_1754 hypothetical protein YP_001183717.1 KEGG: son:SO2595 BNR repeat protein YP_001183718.1 PFAM: protein of unknown function DUF1329; KEGG: she:Shewmr4_1677 protein of unknown function DUF1329 YP_001183719.1 PFAM: protein of unknown function DUF1302; KEGG: son:SO2597 hypothetical protein YP_001183720.1 KEGG: son:SO2598 hypothetical protein YP_001183721.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: shm:Shewmr7_1749 aminopeptidase N YP_001183722.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_001183723.1 affects solute and DNA transport through an unknown mechanism YP_001183724.1 PFAM: GAF domain protein; KEGG: shm:Shewmr7_1746 putative GAF sensor protein YP_001183725.1 PFAM: YebG family protein; KEGG: shm:Shewmr7_1745 YebG family protein YP_001183726.1 PFAM: Paraquat-inducible protein A; KEGG: she:Shewmr4_1669 paraquat-inducible protein A YP_001183727.1 PFAM: Paraquat-inducible protein A; KEGG: shm:Shewmr7_1743 paraquat-inducible protein A YP_001183728.1 PFAM: Mammalian cell entry related domain protein; KEGG: she:Shewmr4_1667 mammalian cell entry related domain protein YP_001183729.1 PFAM: nucleoside recognition domain protein; KEGG: she:Shewmr4_1666 nucleoside recognition domain protein YP_001183730.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_001183731.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: shm:Shewmr7_1739 hydrolase, TatD family YP_001183732.1 KEGG: shm:Shewmr7_1738 type IV pilus biogenesis protein PilZ YP_001183733.1 TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: she:Shewmr4_1662 DNA polymerase III, delta prime subunit YP_001183734.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001183735.1 PFAM: aminodeoxychorismate lyase; KEGG: shm:Shewmr7_1735 aminodeoxychorismate lyase YP_001183736.1 PFAM: aminotransferase, class IV; KEGG: son:SO2615 4-amino-4-deoxychorismate lyase YP_001183737.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001183738.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_001183739.1 KEGG: son:SO2618 ATP-binding protein, Mrp/Nbp35 family YP_001183740.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001183741.1 PFAM: Auxin Efflux Carrier; KEGG: she:Shewmr4_1654 auxin efflux carrier YP_001183742.1 PFAM: protein of unknown function DUF34; KEGG: son:SO2621 conserved hypothetical protein TIGR00486 YP_001183743.1 PFAM: 17 kDa surface antigen; KEGG: she:Shewmr4_1652 17 kDa surface antigen YP_001183744.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001183745.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_001183746.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001183747.1 KEGG: son:SO2626 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001183748.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001183749.1 KEGG: shm:Shewmr7_1721 cold-shock DNA-binding domain protein; TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001183750.1 KEGG: shm:Shewmr7_1681 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type YP_001183751.1 PFAM: pseudouridine synthase; KEGG: she:Shewmr4_1605 pseudouridine synthase, Rsu YP_001183752.1 PFAM: NUDIX hydrolase; KEGG: son:SO2631 MutT/nudix family protein YP_001183753.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001183754.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_001183755.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001183756.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji, jmjC domain protein; KEGG: she:Shewmr4_1600 cupin 4 family protein YP_001183757.1 KEGG: son:SO2637 hypothetical protein YP_001183758.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: she:Shewmr4_1598 Glu/Leu/Phe/Val dehydrogenase, dimerisation region YP_001183759.1 KEGG: shm:Shewmr7_1672 hypothetical protein YP_001183760.1 PFAM: regulatory protein, MarR; KEGG: son:SO2640 transcriptional regulator, MarR family YP_001183761.1 PFAM: protein of unknown function DUF1285; KEGG: son:SO2642 hypothetical protein YP_001183762.1 PFAM: FAD linked oxidase domain protein; KEGG: she:Shewmr4_1593 FAD linked oxidase domain protein YP_001183763.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001183764.1 PFAM: protein of unknown function DUF299; KEGG: shm:Shewmr7_1666 protein of unknown function DUF299 YP_001183765.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_001183766.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_1664 thioesterase superfamily protein YP_001183767.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: she:Shewmr4_1588 two component transcriptional regulator, LuxR family YP_001183768.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_001183769.1 KEGG: she:Shewmr4_1586 hypothetical protein YP_001183770.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001183771.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_001183772.1 PFAM: Ig domain protein, group 1 domain protein; KEGG: sdn:Sden_2330 Ig-like, group 1 YP_001183773.1 PFAM: sodium:dicarboxylate symporter; KEGG: she:Shewmr4_1582 sodium:dicarboxylate symporter YP_001183774.1 KEGG: she:Shewmr4_1581 hypothetical protein YP_001183775.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_1655 two component transcriptional regulator, winged helix family YP_001183776.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO1945 sensor protein PhoQ YP_001183777.1 SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: son:SO1944 hypothetical protein YP_001183778.1 KEGG: son:SO1942 HDIG domain protein; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001183779.1 TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2+ transporter protein, CorA family protein; KEGG: shm:Shewmr7_1720 magnesium and cobalt transport protein CorA YP_001183780.1 KEGG: son:SO1940 hypothetical protein YP_001183781.1 KEGG: she:Shewmr4_1643 hypothetical protein YP_001183782.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_001183783.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_001183784.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1936 acetyltransferase, GNAT family YP_001183785.1 PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: shm:Shewmr7_1714 GreA/GreB family elongation factor YP_001183786.1 TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: son:SO1933 succinyl-CoA synthetase alpha chain YP_001183787.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001183788.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: she:Shewmr4_1636 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase YP_001183789.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001183790.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001183791.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001183792.1 KEGG: she:Shewmr4_1632 conserved hypothetical succinate dehydrogenase, hydrophobic subunit YP_001183793.1 PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: shm:Shewmr7_1706 succinate dehydrogenase, cytochrome b subunit YP_001183794.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001183795.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO1925 HlyD family secretion protein YP_001183796.1 PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_1628 acriflavin resistance protein YP_001183797.1 PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_1627 acriflavin resistance protein YP_001183798.1 PFAM: Uncharacterized conserved protein UCP029143; KEGG: she:Shewmr4_1625 uncharacterized conserved protein UCP029143 YP_001183799.1 KEGG: son:SO1921 hypothetical protein YP_001183800.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; virulence factor MVIN family protein; KEGG: she:Shewmr4_1623 MATE efflux family protein YP_001183801.1 PFAM: Ion transport protein; Ion transport 2 domain protein,; KEGG: she:Shewmr4_2209 ion transport protein YP_001183802.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: shm:Shewmr7_2287 hypothetical protein YP_001183803.1 PFAM: protein of unknown function DUF991; KEGG: son:SO2182 hypothetical protein YP_001183804.1 KEGG: shm:Shewmr7_2289 hypothetical protein YP_001183805.1 PFAM: peptidase M23B; KEGG: son:SO2180 peptidase, M23/M37 family YP_001183806.1 KEGG: shm:Shewmr7_2291 hypothetical protein YP_001183807.1 PFAM: Di-haem cytochrome c peroxidase; KEGG: son:SO2178 cytochrome c551 peroxidase YP_001183808.1 PFAM: 37kDa nucleoid-associated protein; KEGG: son:SO2177 hypothetical protein YP_001183809.2 PFAM: protein of unknown function DUF1414; KEGG: shm:Shewmr7_2294 protein of unknown function DUF1414 YP_001183810.1 PFAM: sulfatase; KEGG: she:Shewmr4_2219 sulfatase YP_001183811.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: shm:Shewmr7_2296 NADH:flavin oxidoreductase/NADH oxidase YP_001183812.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2297 transcriptional regulator, LysR family YP_001183813.1 KEGG: shm:Shewmr7_2317 hypothetical protein YP_001183814.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001183815.1 PFAM: PfkB domain protein; KEGG: son:SO2020 inosine-guanosine kinase YP_001183816.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001183817.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001183818.1 PFAM: Thioredoxin domain; KEGG: she:Shewmr4_2250 thioredoxin domain YP_001183819.1 molecular chaperone YP_001183820.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001183821.1 PFAM: conserved hypothetical protein 103; KEGG: she:Shewmr4_2253 conserved hypothetical protein 103 YP_001183822.1 KEGG: son:SO2013 DNA polymerase III, gamma and tau subunits; TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase YP_001183823.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001183824.1 PFAM: protein of unknown function DUF454; KEGG: she:Shewmr4_2256 protein of unknown function DUF454 YP_001183825.1 KEGG: shm:Shewmr7_2329 hypothetical protein YP_001183826.1 KEGG: she:Shewmr4_2258 hypothetical protein YP_001183827.1 PFAM: protein of unknown function DUF692; KEGG: son:SO2008 hypothetical protein YP_001183828.1 KEGG: shm:Shewmr7_2332 hypothetical protein YP_001183829.1 PFAM: dihydrouridine synthase, DuS; KEGG: shm:Shewmr7_2333 dihydrouridine synthase, DuS YP_001183830.1 KEGG: shm:Shewmr7_2334 transcriptional regulators, TraR/DksA family YP_001183831.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_001183832.1 PFAM: phospholipase/Carboxylesterase; KEGG: son:SO1999 phospholipase/carboxylesterase family protein YP_001183833.1 KEGG: shm:Shewmr7_2338 hypothetical protein YP_001183834.1 PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: shm:Shewmr7_2339 peptidase M1, membrane alanine aminopeptidase YP_001183835.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO1995 peptidyl-prolyl cis-trans isomerase, FkbP family YP_001183836.1 TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: she:Shewmr4_2269 lytic murein transglycosylase YP_001183837.1 KEGG: shm:Shewmr7_2342 hypothetical protein YP_001183838.1 KEGG: shm:Shewmr7_2343 hypothetical protein YP_001183839.1 PFAM: response regulator receiver; CheW domain protein; KEGG: she:Shewmr4_2272 response regulator receiver modulated CheW protein YP_001183840.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO1988 hypothetical methyltransferase YP_001183841.1 PFAM: peptidase S16, lon domain protein; KEGG: shm:Shewmr7_2346 peptidase S16, lon domain protein YP_001183842.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: son:SO1986 RNA polymerase sigma-70 factor, ECF subfamily YP_001183843.1 TIGRFAM: anti-sigma factor, putative, ChrR family; KEGG: she:Shewmr4_2276 anti-ECFsigma factor, ChrR YP_001183844.1 KEGG: shm:Shewmr7_2349 hypothetical protein YP_001183845.1 KEGG: shm:Shewmr7_2350 hypothetical protein YP_001183846.1 PFAM: Nicotinate phosphoribosyltransferase and related; KEGG: son:SO1981 hypothetical protein YP_001183847.1 KEGG: son:SO1980 phosphoribosyl transferase domain protein; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase YP_001183848.1 PFAM: NUDIX hydrolase; KEGG: son:SO1979 MutT/nudix family protein YP_001183849.1 KEGG: son:SO1978 hypothetical protein YP_001183850.1 PFAM: protein of unknown function DUF307; KEGG: son:SO1977 hypothetical protein YP_001183851.1 KEGG: son:SO2890 hypothetical protein YP_001183852.1 PFAM: regulatory protein, LuxR; KEGG: shm:Shewmr7_2386 transcriptional regulator, LuxR family YP_001183853.1 KEGG: shm:Shewmr7_2388 cytochrome c3 YP_001183854.1 putative metalloprotease YP_001183855.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_001183856.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_001183857.1 KEGG: shm:Shewmr7_2427 hypothetical protein YP_001183858.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: mka:MK0066 biopolymer transport protein YP_001183859.1 KEGG: mbu:Mbur_2259 hypothetical protein YP_001183860.1 PFAM: CobN/magnesium chelatase; KEGG: mba:Mbar_A3731 cobalamin biosynthesis protein N YP_001183861.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: dar:Daro_4029 TonB-dependent receptor YP_001183862.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001183863.1 TIGRFAM: biotin biosynthesis protein BioC; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: she:Shewmr4_2357 biotin biosynthesis protein BioC YP_001183864.1 PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: son:SO2739 8-amino-7-oxononanoate synthase YP_001183865.1 KEGG: shm:Shewmr7_2431 biotin synthase; TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_001183866.1 TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: son:SO2741 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_001183867.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: vch:VC1248 methyl-accepting chemotaxis protein YP_001183868.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO2742 sensor histidine kinase/response regulator YP_001183869.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001183870.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_2435 type III restriction enzyme, res subunit YP_001183871.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_001183872.1 KEGG: son:SO3573 hypothetical protein YP_001183873.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_001183874.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: she:Shewmr4_1521 transcriptional regulator, GntR family YP_001183875.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis YP_001183876.1 PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: she:Shewmr4_1516 exonuclease, RNase T and DNA polymerase III YP_001183877.1 PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294, nucleotidyltransferase putative; KEGG: shm:Shewmr7_1582 cyclic nucleotide-binding protein YP_001183878.1 PFAM: Na+/solute symporter; KEGG: shm:Shewmr7_1581 Na+/solute symporter YP_001183879.1 KEGG: son:SO2858 hypothetical protein YP_001183880.1 PFAM: DSBA oxidoreductase; KEGG: son:SO2860 thiol:disulfide interchange protein, DsbA family YP_001183881.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: shm:Shewmr7_1578 NAD-dependent epimerase/dehydratase YP_001183882.1 TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; KEGG: she:Shewmr4_1510 metal dependent phosphohydrolase YP_001183883.1 KEGG: son:SO2863 hypothetical protein YP_001183884.1 KEGG: son:SO2896 DNA ligase, NAD-dependent; TIGRFAM: DNA ligase, NAD-dependent; PFAM: helix-hairpin-helix motif; BRCT domain protein; zinc-finger, NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase, OB-fold; NAD-dependent DNA ligase, adenylation; SMART: Helix-hairpin-helix DNA-binding, class 1; NAD-dependent DNA ligase-like YP_001183885.1 TIGRFAM: cell division protein ZipA; PFAM: ZipA, C-terminal FtsZ-binding region; KEGG: she:Shewmr4_1507 cell division protein ZipA YP_001183886.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; KEGG: son:SO2898 SMC family protein YP_001183887.1 putative role in sulfur assimilation YP_001183888.1 catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001183889.1 PFAM: RDD domain containing protein; KEGG: she:Shewmr4_1501 RDD domain containing protein YP_001183890.1 TIGRFAM: cysteine synthases; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: son:SO2903 cysteine synthase A YP_001183891.1 PFAM: O-methyltransferase, family 2; KEGG: shm:Shewmr7_1566 methyltransferase type 12 YP_001183892.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: son:SO2906 hypothetical protein YP_001183893.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_2471 TonB-dependent receptor YP_001183894.1 PFAM: C4-dicarboxylate anaerobic carrier; KEGG: shm:Shewmr7_1563 C4-dicarboxylate anaerobic carrier YP_001183895.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sfr:Sfri_2469 transcriptional regulator, LysR family protein YP_001183896.1 PFAM: formate/nitrite transporter; CBS domain containing protein; KEGG: sfr:Sfri_2470 formate/nitrite transporter YP_001183897.1 KEGG: sfr:Sfri_2472 hypothetical protein YP_001183898.1 KEGG: son:SO2912 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL YP_001183899.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_001183900.1 PFAM: protein of unknown function DUF412; KEGG: shm:Shewmr7_1559 protein of unknown function DUF412 YP_001183901.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001183902.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001183903.1 KEGG: son:SO2917 hypothetical protein YP_001183904.1 KEGG: shm:Shewmr7_1553 hypothetical protein YP_001183905.1 KEGG: son:SO2919 hypothetical protein YP_001183906.1 PFAM: protein of unknown function UPF0118; KEGG: shm:Shewmr7_1550 protein of unknown function UPF0118 YP_001183907.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_001183908.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; domain of unknown function DUF1731; KEGG: shm:Shewmr7_1548 hypothetical protein YP_001183909.1 PFAM: sodium/glutamate symporter; KEGG: son:SO2923 sodium/glutamate symporter YP_001183910.1 PFAM: protein of unknown function DUF214; KEGG: son:SO2926 ABC transporter, permease, putative YP_001183911.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: she:Shewmr4_1479 ABC transporter related YP_001183912.1 PFAM: lipolytic enzyme, G-D-S-L family; KEGG: she:Shewmr4_1478 arylesterase YP_001183913.1 KEGG: shm:Shewmr7_1542 hypothetical protein YP_001183914.1 SohB; periplasmic protein; member of the peptidase S49 family YP_001183915.1 KEGG: she:Shewmr4_1469 hypothetical protein YP_001183916.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_1534 short-chain dehydrogenase/reductase SDR YP_001183917.1 KEGG: son:SO2936 hypothetical protein YP_001183918.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: shm:Shewmr7_1533 pseudouridine synthase, Rsu YP_001183919.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB; KEGG: shm:Shewmr7_1532 putative transcriptional regulator YP_001183920.1 PFAM: chromosome segregation and condensation protein ScpA; KEGG: son:SO3015 putative segregation and condensation protein A YP_001183921.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: son:SO3016 Sua5/YciO/YrdC/YwlC family protein YP_001183922.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; KEGG: she:Shewmr4_1463 PHP C-terminal domain protein YP_001183923.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001183924.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001183925.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001183926.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_001183927.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001183928.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001183929.1 KEGG: she:Shewmr4_1456 hypothetical protein YP_001183930.1 KEGG: son:SO3029 hypothetical protein YP_001183931.1 KEGG: shm:Shewmr7_1520 L-lysine 6-monooxygenase (NADPH) YP_001183932.1 KEGG: son:SO3031 siderophore biosynthesis protein, putative YP_001183933.1 PFAM: IucA/IucC family protein; KEGG: she:Shewmr4_1452 IucA/IucC family protein YP_001183934.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_1517 TonB-dependent siderophore receptor YP_001183935.1 PFAM: ferric iron reductase; KEGG: son:SO3034 ferric iron reductase protein, putative YP_001183936.1 Involved in cell division; probably involved in intracellular septation YP_001183937.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_001183938.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_001183939.1 KEGG: rpe:RPE_3539 hypothetical protein YP_001183940.1 KEGG: shm:Shewmr7_1510 hypothetical protein YP_001183941.1 KEGG: son:SO3045 hypothetical protein YP_001183942.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_1442 methyl-accepting chemotaxis sensory transducer YP_001183943.1 PFAM: protein of unknown function DUF1097; KEGG: shm:Shewmr7_1506 protein of unknown function DUF1097 YP_001183944.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: son:SO3048 isoquinoline 1-oxidoreductase, beta subunit, putative YP_001183945.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: shm:Shewmr7_1504 (2Fe-2S)-binding domain protein YP_001183946.1 KEGG: she:Shewmr4_1438 hypothetical protein YP_001183947.1 PFAM: protein of unknown function DUF182; KEGG: she:Shewmr4_1437 protein of unknown function DUF182 YP_001183948.1 PFAM: beta-lactamase domain protein; KEGG: shm:Shewmr7_1500 beta-lactamase domain protein YP_001183949.1 PFAM: alpha/beta hydrolase fold; KEGG: she:Shewmr4_1434 alpha/beta hydrolase fold YP_001183950.1 KEGG: son:SO3056 tetraheme cytochrome c YP_001183951.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: son:SO3057 Pal/histidase family protein YP_001183952.1 TIGRFAM: flavocytochrome c; PFAM: monooxygenase, FAD-binding; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO3058 flavocytochrome c flavin subunit, putative YP_001183953.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: son:SO3059 formate hydrogenlyase transcriptional activator, putative YP_001183954.1 PFAM: porin, Gram-negative type; KEGG: son:SO3060 outer membrane porin, putative YP_001183955.1 decatenates replicating daughter chromosomes YP_001183956.1 KEGG: shm:Shewmr7_1497 hypothetical protein YP_001183957.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001183958.1 PFAM: Colicin V production protein; KEGG: son:SO3065 colicin V production protein YP_001183959.1 PFAM: Sporulation domain protein; KEGG: shm:Shewmr7_1493 sporulation domain protein YP_001183960.1 KEGG: she:Shewmr4_1427 FolC bifunctional protein; TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein YP_001183961.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001183962.1 KEGG: shm:Shewmr7_1490 hypothetical protein YP_001183963.1 KEGG: shm:Shewmr7_1489 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region YP_001183964.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: son:SO3071 erythronate-4-phosphate dehydrogenase YP_001183965.1 PFAM: beta-ketoacyl synthase; KEGG: shm:Shewmr7_1487 beta-ketoacyl synthase YP_001183966.1 PFAM: FAD dependent oxidoreductase; KEGG: shm:Shewmr7_1486 FAD dependent oxidoreductase YP_001183967.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: shm:Shewmr7_1485 tRNA/rRNA methyltransferase (SpoU) YP_001183968.1 KEGG: she:Shewmr4_1419 hypothetical protein YP_001183969.1 PFAM: ATP-NAD/AcoX kinase; KEGG: son:SO3077 hypothetical protein YP_001183970.1 PFAM: nucleoside:H+ symporter; major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_1482 major facilitator superfamily MFS_1 YP_001183971.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001183972.1 involved in methylation of ribosomal protein L3 YP_001183973.1 PFAM: Smr protein/MutS2; KEGG: son:SO3081 Smr domain protein YP_001183974.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase; KEGG: she:Shewmr4_1413 phosphohistidine phosphatase, SixA YP_001183975.1 PFAM: peptidase M16 domain protein; KEGG: shm:Shewmr7_1477 peptidase M16 domain protein YP_001183976.1 KEGG: she:Shewmr4_1411 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; Two component regulator three Y domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001183977.1 KEGG: son:SO3085 hypothetical protein YP_001183978.1 KEGG: son:SO3087 hypothetical protein YP_001183979.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_001183980.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_001183981.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; KEGG: shm:Shewmr7_1471 ATPase associated with various cellular activities, AAA_3 YP_001183982.1 PFAM: protein of unknown function DUF58; KEGG: son:SO3091 hypothetical protein YP_001183983.1 KEGG: shm:Shewmr7_1469 hypothetical protein YP_001183984.1 PFAM: von Willebrand factor, type A; KEGG: shm:Shewmr7_1468 von Willebrand factor, type A YP_001183985.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: von Willebrand factor, type A; Tetratricopeptide domain protein; KEGG: she:Shewmr4_1402 tetratricopeptide TPR_2 repeat protein YP_001183986.1 KEGG: shm:Shewmr7_1466 hypothetical protein YP_001183987.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001183988.1 KEGG: she:Shewmr4_1399 hypothetical protein YP_001183989.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: shm:Shewmr7_1463 sodium/proline symporter YP_001183990.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: son:SO3099 long-chain fatty acid transport protein, putative YP_001183991.1 KEGG: shm:Shewmr7_1461 hypothetical protein YP_001183992.1 PFAM: protein of unknown function DUF541; KEGG: shm:Shewmr7_1460 protein of unknown function DUF541 YP_001183993.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_1394 efflux transporter, RND family, MFP subunit YP_001183994.1 PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_1393 acriflavin resistance protein YP_001183995.1 KEGG: shm:Shewmr7_1457 hypothetical protein YP_001183996.1 PFAM: Rhodanese domain protein; KEGG: son:SO3105 phage shock protein E YP_001183997.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; Proprotein convertase, P; protease-associated PA domain protein; peptidase domain protein; proteinase inhibitor I9, subtilisin propeptide; KEGG: shm:Shewmr7_1455 peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001183998.1 PFAM: YaeQ family protein; KEGG: son:SO3107 hypothetical protein YP_001183999.1 TIGRFAM: siroheme synthase; KEGG: son:SO3108 precorrin-2 oxidase / ferrochelatase YP_001184000.1 KEGG: shm:Shewmr7_1451 hypothetical protein YP_001184001.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001184002.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001184003.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_001184004.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001184005.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001184006.1 KEGG: son:SO3115 hypothetical protein YP_001184007.1 PFAM: protein of unknown function DUF479; KEGG: shm:Shewmr7_1444 protein of unknown function DUF479 YP_001184008.1 PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_1442 pseudouridylate synthase YP_001184009.1 KEGG: son:SO3119 hypothetical protein YP_001184010.1 PFAM: oxidoreductase domain protein; KEGG: shm:Shewmr7_1440 twin-arginine translocation pathway signal YP_001184011.1 PFAM: NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30; KEGG: son:SO3121 hypothetical protein YP_001184012.1 involved in the import of serine and threonine coupled with the import of sodium YP_001184013.1 PFAM: response regulator receiver; CheW domain protein; KEGG: shm:Shewmr7_1437 response regulator receiver modulated CheW protein YP_001184014.1 PFAM: Dual specificity protein phosphatase; KEGG: son:SO3124 tyrosine-specific protein phosphatase, putative YP_001184015.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_1434 DEAD/DEAH box helicase domain protein YP_001184016.1 KEGG: shm:Shewmr7_1433 methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase YP_001184017.1 PFAM: helix-turn-helix- domain containing protein, AraC type; HhH-GPD family protein; Ada, metal-binding domain protein; AlkA domain protein; KEGG: son:SO3127 Ada regulatory protein, putative YP_001184018.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: she:Shewmr4_1366 ABC transporter related YP_001184019.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001184020.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: shm:Shewmr7_1428 TRAP dicarboxylate transporter, DctP subunit YP_001184021.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: she:Shewmr4_1362 tripartite ATP-independent periplasmic transporter, DctQ component YP_001184022.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: shm:Shewmr7_1426 TRAP dicarboxylate transporter, DctM subunit YP_001184023.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_1360 periplasmic sensor signal transduction histidine kinase YP_001184024.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_1424 two component, sigma54 specific, transcriptional regulator, fis family YP_001184025.1 KEGG: she:Shewmr4_1358 hypothetical protein YP_001184026.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_001184027.1 KEGG: she:Shewmr4_1356 hypothetical protein YP_001184028.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: shm:Shewmr7_1420 peptidyl-dipeptidase DCP YP_001184029.1 PFAM: Na+/H+ antiporter NhaC; KEGG: shm:Shewmr7_1419 Na+/H+ antiporter NhaC YP_001184030.1 PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit; KEGG: shm:Shewmr7_1418 electron transfer flavoprotein, alpha subunit YP_001184031.1 PFAM: electron transfer flavoprotein beta-subunit; KEGG: shm:Shewmr7_1417 electron transfer flavoprotein beta-subunit YP_001184032.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: shm:Shewmr7_1416 histone family protein nucleoid-structuring protein H-NS YP_001184033.1 PFAM: amidohydrolase; KEGG: shm:Shewmr7_1415 amidohydrolase YP_001184034.1 KEGG: son:SO3149 hypothetical protein YP_001184035.1 KEGG: shm:Shewmr7_1413 lipoprotein, putative YP_001184036.1 PFAM: protein of unknown function UPF0066; KEGG: she:Shewmr4_1347 protein of unknown function UPF0066 YP_001184037.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: shm:Shewmr7_1411 transferase hexapeptide repeat containing protein YP_001184038.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001184039.1 PFAM: Patatin; KEGG: shm:Shewmr7_1409 patatin YP_001184040.1 KEGG: son:SO3156.1 hypothetical protein YP_001184041.1 KEGG: she:Shewmr4_1342 lipoprotein, putative YP_001184042.1 PFAM: protein of unknown function DUF1017; KEGG: shm:Shewmr7_1406 protein of unknown function DUF1017 YP_001184043.1 PFAM: protein of unknown function DUF940, membrane lipoprotein putative; KEGG: son:SO3159 hypothetical protein YP_001184044.1 PFAM: Excinuclease ABC, C subunit domain protein; KEGG: nme:NMB0047 putative endonuclease YP_001184045.1 PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein; KEGG: son:SO3162 sensor histidine kinase YP_001184046.1 PFAM: copper resistance lipoprotein NlpE; KEGG: son:SO3163 lipoprotein YP_001184047.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: son:SO3171 polysaccharide biosynthesis protein YP_001184048.1 PFAM: sugar transferase; KEGG: son:SO3172 galactosyl transferase YP_001184049.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: vvu:VV10777 nucleoside-diphosphate-sugar epimerase YP_001184050.1 PFAM: glycosyl transferase, family 2; KEGG: gme:Gmet_1334 glycosyl transferase, family 2 YP_001184051.1 PFAM: glycosyl transferase, family 2; KEGG: spd:SPD_0321 glycosyl transferase, group 2 family protein YP_001184052.1 KEGG: bfs:BF1561 putative transmembrane protein YP_001184053.1 PFAM: glycosyl transferase, family 2; KEGG: ana:all1766 probable glycosyl transferase YP_001184054.1 KEGG: pfl:PFL_5102 glycosyltransferase, putative YP_001184055.1 PFAM: polysaccharide biosynthesis protein; KEGG: bfs:BF1369 putative LPS biosynthesis related flippase YP_001184056.1 PFAM: glycosyl transferase, group 1; KEGG: cac:CAC2313 glycosyltransferase YP_001184057.1 KEGG: sbo:SBO_0865 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_001184058.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: sdn:Sden_2661 dTDP-4-dehydrorhamnose reductase YP_001184059.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sfr:Sfri_2829 glucose-1-phosphate thymidylyltransferase YP_001184060.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose YP_001184061.1 PFAM: lipopolysaccharide biosynthesis; KEGG: son:SO3191 chain length determinant protein YP_001184062.1 crystal structure of protein from Xanthomonas shows pentameric toroidal structure; physiological function is unknown YP_001184063.1 PFAM: polysaccharide export protein; KEGG: son:SO3193 polysaccharide biosynthesis protein YP_001184064.1 KEGG: son:SO3194 transcriptional activator rfaH, putative; TIGRFAM: transcriptional activator RfaH; PFAM: transcription antitermination protein NusG; SMART: NGN domain protein YP_001184065.1 TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor, type I/II extracellular region; major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_1380 amino acid/peptide transporter YP_001184066.1 PFAM: response regulator receiver; KEGG: shm:Shewmr7_1379 response regulator receiver protein YP_001184067.1 PFAM: VacJ family lipoprotein; KEGG: shm:Shewmr7_1378 VacJ family lipoprotein YP_001184068.1 KEGG: she:Shewmr4_1310 hypothetical protein YP_001184069.1 KEGG: shm:Shewmr7_1376 FlhB domain protein YP_001184070.1 KEGG: shm:Shewmr7_1375 hypothetical protein YP_001184071.1 PFAM: CheW domain protein; KEGG: shm:Shewmr7_1374 CheW protein YP_001184072.1 PFAM: CheW domain protein; KEGG: she:Shewmr4_1306 CheW protein YP_001184073.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: son:SO3204 ParA family protein YP_001184074.1 KEGG: she:Shewmr4_1304 hypothetical protein YP_001184075.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001184076.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: shm:Shewmr7_1369 CheA signal transduction histidine kinases YP_001184077.1 PFAM: Chemotaxis phosphatase, CheZ; KEGG: shm:Shewmr7_1368 chemotaxis phosphatase, CheZ YP_001184078.1 PFAM: response regulator receiver; KEGG: shm:Shewmr7_1367 response regulator receiver protein YP_001184079.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001184080.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: shm:Shewmr7_1365 cobyrinic acid a,c-diamide synthase YP_001184081.1 positive regulator of class III flagellar genes YP_001184082.1 membrane protein involved in the flagellar export apparatus YP_001184083.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001184084.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001184085.1 TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ, family 3; KEGG: son:SO3217 flagellar biosynthetic protein FliQ YP_001184086.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001184087.1 PFAM: flagellar biosynthesis protein, FliO; KEGG: she:Shewmr4_1291 flagellar biosynthesis protein, FliO YP_001184088.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001184089.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001184090.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_001184091.1 PFAM: flagellar hook-length control protein; KEGG: son:SO3223 flagellar hook-length control protein FliK YP_001184092.1 TIGRFAM: flagellar export protein FliJ; KEGG: shm:Shewmr7_1353 flagellar export protein FliJ YP_001184093.1 involved in type III protein export during flagellum assembly YP_001184094.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001184095.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001184096.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001184097.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: she:Shewmr4_1281 flagellar hook-basal body complex subunit FliE YP_001184098.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: she:Shewmr4_1280 two component, sigma54 specific, transcriptional regulator, fis family YP_001184099.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; SMART: PAS domain containing protein; KEGG: son:SO3231 flagellar regulatory protein B YP_001184100.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; flagellar regulatory FleQ domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_1345 sigma54 specific transcriptional regulator, fis family YP_001184101.1 flagellin specific chaperone YP_001184102.1 KEGG: son:SO3234 hypothetical protein YP_001184103.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; KEGG: son:SO3235 flagellar hook-associated protein FliD YP_001184104.1 PFAM: flagellar protein FlaG protein; KEGG: son:SO3236 flagellin FlaG YP_001184105.1 PFAM: flagellin domain protein; KEGG: sdn:Sden_1315 flagellin-like protein YP_001184106.1 PFAM: flagellin domain protein; KEGG: sdn:Sden_1314 flagellin-like protein YP_001184107.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes. YP_001184108.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: she:Shewmr4_1268 flagellar hook-associated protein FlgK YP_001184109.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_001184110.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001184111.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001184112.1 makes up the distal portion of the flagellar basal body rod YP_001184113.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_001184114.1 the hook connects flagellar basal body to the flagellar filament YP_001184115.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_001184116.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001184117.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod YP_001184118.1 PFAM: MCP methyltransferase, CheR-type; Methyltransferase type 12; KEGG: son:SO3251 chemotaxis protein methyltransferase CheR YP_001184119.1 PFAM: response regulator receiver; CheW domain protein; KEGG: son:SO3252 chemotaxis protein CheV YP_001184120.1 required for the assembly of the flagellar basal body P-ring YP_001184121.1 PFAM: Anti-sigma-28 factor, FlgM family protein; KEGG: shm:Shewmr7_1325 anti-sigma-28 factor, FlgM YP_001184122.1 PFAM: FlgN family protein; KEGG: shm:Shewmr7_1324 FlgN family protein YP_001184123.1 PFAM: protein of unknown function DUF400; KEGG: son:SO3256 hypothetical protein YP_001184124.1 KEGG: shm:Shewmr7_1322 hypothetical protein YP_001184125.1 KEGG: she:Shewmr4_1251 hypothetical protein YP_001184129.1 PFAM: bacteriophage replication gene A; KEGG: vvy:VV1773 A protein YP_001184130.1 KEGG: vvy:VV1770 hypothetical protein YP_001184131.1 KEGG: vvy:VV1771 retron-type reverse transcriptase YP_001184132.1 PFAM: phage integrase family protein; KEGG: pol:Bpro_2964 phage integrase YP_001184133.1 KEGG: son:SO3259 hypothetical protein YP_001184134.1 KEGG: son:SO3260 hypothetical protein YP_001184135.1 KEGG: pau:PA14_50310 possible sugar nucleotidyltransferase YP_001184136.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pau:PA14_50320 hypothetical protein YP_001184137.1 PFAM: Methyltransferase type 12; KEGG: pau:PA14_50330 hypothetical protein YP_001184138.1 KEGG: bfr:BF2579 putative cholinephosphotransferase YP_001184139.1 KEGG: sus:Acid_1365 hypothetical protein YP_001184140.1 PFAM: acyl-protein synthetase, LuxE; KEGG: sus:Acid_1364 acyl-protein synthetase, LuxE YP_001184141.1 PFAM: AMP-dependent synthetase and ligase; KEGG: rha:RHA1_ro07030 possible acyl-CoA synthetase YP_001184142.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: sus:Acid_1362 short-chain dehydrogenase/reductase SDR YP_001184143.1 KEGG: sus:Acid_1361 acyl carrier protein YP_001184144.1 KEGG: sus:Acid_6945 GCN5-related N-acetyltransferase YP_001184145.1 PFAM: N-acetylneuraminic acid synthase, N-terminal domain; SAF domain; KEGG: pfl:PFL_1625 NeuB family protein YP_001184146.1 KEGG: pfl:PFL_1624 FlaR protein (FlaR) YP_001184147.1 PFAM: acylneuraminate cytidylyltransferase; KEGG: par:Psyc_0656 putative acylneuraminate cytidylyltransferase YP_001184148.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: son:SO3270 polysaccharide biosynthesis protein YP_001184149.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: son:SO3271 polysaccharide biosynthesis protein YP_001184150.1 PFAM: protein of unknown function DUF115; KEGG: son:SO3273 hypothetical protein YP_001184151.1 KEGG: shm:Shewmr7_1320 hypothetical protein YP_001184152.1 KEGG: shm:Shewmr7_1319 hypothetical protein YP_001184153.1 KEGG: she:Shewmr4_1248 hypothetical protein YP_001184154.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_1317 transcriptional regulator, TetR family YP_001184155.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO3278 hypothetical protein YP_001184156.1 PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_1245 acriflavin resistance protein YP_001184157.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_1243 methyl-accepting chemotaxis sensory transducer YP_001184158.1 KEGG: she:Shewmr4_1960 hypothetical protein YP_001184159.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: shm:Shewmr7_1312 cyd operon protein YbgT YP_001184160.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II; KEGG: son:SO3285 cytochrome bd-I oxidase subunit II YP_001184161.1 PFAM: cytochrome bd ubiquinol oxidase, subunit I; KEGG: shm:Shewmr7_1310 cytochrome bd ubiquinol oxidase, subunit I YP_001184162.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001184163.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_001184164.1 PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: she:Shewmr4_1236 CMP/dCMP deaminase, zinc-binding YP_001184165.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001184166.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001184167.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001184168.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001184169.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_001184170.1 KEGG: shm:Shewmr7_1301 hypothetical protein YP_001184171.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001184172.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001184173.1 KEGG: she:Shewmr4_1227 hypothetical protein YP_001184174.1 KEGG: she:Shewmr4_1226 type IV pilus biogenesis/stability protein PilW; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001184175.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001184176.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; KEGG: shm:Shewmr7_1295 protein of unknown function DUF21 YP_001184177.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: shm:Shewmr7_1294 metallophosphoesterase YP_001184178.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_1222 transcriptional regulator, LysR family YP_001184179.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: son:SO4548 transposase, IS110 family YP_001184180.1 KEGG: net:Neut_0366 hypothetical protein YP_001184181.1 KEGG: shm:Shewmr7_1292 DoxX family protein YP_001184182.1 PFAM: Pirin domain protein domain protein; Cupin 2, conserved barrel domain protein; KEGG: shm:Shewmr7_1291 pirin domain protein domain protein YP_001184183.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_1219 GCN5-related N-acetyltransferase YP_001184184.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_1289 GCN5-related N-acetyltransferase YP_001184185.1 KEGG: shm:Shewmr7_1288 NrfJ-related protein YP_001184186.1 KEGG: she:Shewmr4_1216 hypothetical protein YP_001184187.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO3328 acetyltransferase, GNAT family YP_001184188.1 PFAM: extracellular solute-binding protein, family 1; KEGG: she:Shewmr4_1212 extracellular solute-binding protein, family 1 YP_001184189.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO3334 GGDEF family protein YP_001184190.1 PFAM: protein of unknown function DUF980; KEGG: she:Shewmr4_1210 protein of unknown function DUF980 YP_001184191.1 PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: she:Shewmr4_1207 threonine aldolase YP_001184192.1 PFAM: OmpA/MotB domain protein; KEGG: son:SO3339 OmpA family protein YP_001184193.1 PFAM: MscS Mechanosensitive ion channel; KEGG: shm:Shewmr7_1276 MscS mechanosensitive ion channel YP_001184194.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shm:Shewmr7_1275 redoxin domain protein YP_001184195.1 PFAM: protein of unknown function UPF0126; KEGG: shm:Shewmr7_1274 protein of unknown function UPF0126 YP_001184196.1 KEGG: son:SO3343 hypothetical protein YP_001184197.1 KEGG: shm:Shewmr7_1272 hypothetical protein YP_001184198.1 involved in start site selection during the initiation of translation YP_001184199.1 PFAM: protein of unknown function DUF179; KEGG: son:SO3346 putative transcriptional regulator YP_001184200.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001184201.1 PFAM: ferrochelatase; KEGG: shm:Shewmr7_1268 ferrochelatase YP_001184202.1 PFAM: glutathione peroxidase; KEGG: shm:Shewmr7_1267 glutathione peroxidase YP_001184203.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: shm:Shewmr7_1266 twitching motility protein YP_001184204.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: son:SO3351 twitching motility protein PilT YP_001184205.1 PFAM: alanine racemase domain protein; KEGG: shm:Shewmr7_1264 protein of unknown function UPF0001 YP_001184206.1 KEGG: son:SO3354 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent YP_001184207.1 PFAM: protein of unknown function YGGT; KEGG: she:Shewmr4_1191 protein of unknown function YGGT YP_001184208.1 PFAM: protein of unknown function DUF167; KEGG: son:SO3356 hypothetical protein YP_001184209.1 KEGG: shm:Shewmr7_1260 hypothetical protein YP_001184210.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001184211.1 KEGG: she:Shewmr4_1187 putative oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001184212.1 PFAM: protein of unknown function DUF885; KEGG: she:Shewmr4_1186 protein of unknown function DUF885 YP_001184213.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_1256 transcriptional regulator, LysR family YP_001184214.1 KEGG: shm:Shewmr7_1255 hypothetical protein YP_001184215.1 catalyzes the formation of glutamate from glutamine YP_001184216.1 PFAM: protein of unknown function DUF469; KEGG: son:SO3366 hypothetical protein YP_001184217.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001184218.1 TIGRFAM: A/G-specific adenine glycosylase; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: shm:Shewmr7_1251 A/G-specific adenine glycosylase YP_001184219.1 PFAM: Fe(II) trafficking protein YggX; KEGG: son:SO3369 hypothetical protein YP_001184220.1 PFAM: YceI family protein; KEGG: son:SO3370 hypothetical protein YP_001184221.1 PFAM: cytochrome B561; KEGG: she:Shewmr4_1177 cytochrome b561 YP_001184222.1 KEGG: shm:Shewmr7_1247 hypothetical protein YP_001184223.1 KEGG: son:SO3374 hypothetical protein YP_001184224.1 KEGG: shm:Shewmr7_1244 hypothetical protein YP_001184225.1 KEGG: son:SO3377 hypothetical protein YP_001184226.1 KEGG: son:SO3378 hypothetical protein YP_001184227.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO3379 cyclopropane-fatty-acyl-phospholipid synthase YP_001184228.1 PFAM: protein of unknown function DUF1365; KEGG: she:Shewmr4_1169 protein of unknown function DUF1365 YP_001184229.1 PFAM: amine oxidase; KEGG: shm:Shewmr7_1239 amine oxidase YP_001184230.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: she:Shewmr4_1167 short-chain dehydrogenase/reductase SDR YP_001184231.1 KEGG: shm:Shewmr7_1237 transcriptional regulator-related protein YP_001184232.1 PFAM: DNA photolyase, FAD-binding; DNA photolyase domain protein; KEGG: son:SO3384 deoxyribodipyrimidine photolyase YP_001184233.1 PFAM: regulatory protein, MerR; KEGG: son:SO3385 transcriptional regulator, MerR family YP_001184234.1 PFAM: protein of unknown function DUF523; Protein of unknown function DUF1722; KEGG: shm:Shewmr7_1234 protein of unknown function DUF1722 YP_001184235.1 KEGG: she:Shewmr4_1162 hypothetical protein YP_001184236.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO3388 ATP-dependent RNA helicase, DEAD box family YP_001184237.1 KEGG: shm:Shewmr7_1230 peptidase S16, lon domain protein YP_001184238.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: shm:Shewmr7_1229 NADH:flavin oxidoreductase/NADH oxidase YP_001184239.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_1228 transcriptional regulator, TetR family YP_001184240.1 KEGG: shm:Shewmr7_1227 hypothetical protein YP_001184241.1 PFAM: chemotaxis sensory transducer; KEGG: shm:Shewmr7_1226 methyl-accepting chemotaxis sensory transducer YP_001184242.1 PFAM: protein of unknown function DUF28; KEGG: son:SO3401 hypothetical protein YP_001184243.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: shm:Shewmr7_1221 sigma 54 modulation protein/ribosomal protein S30EA YP_001184244.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; KEGG: she:Shewmr4_1149 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor YP_001184245.1 KEGG: shm:Shewmr7_1219 hypothetical protein YP_001184246.1 PFAM: PepSY-associated TM helix domain protein; KEGG: son:SO3407 hypothetical protein YP_001184247.1 KEGG: she:Shewmr4_1146 hypothetical protein YP_001184248.1 PFAM: OsmC family protein; KEGG: son:SO3409 OsmC/Ohr family protein YP_001184249.1 PFAM: peptidase S41; WD40 domain protein beta Propeller; SMART: PDZ/DHR/GLGF domain protein; KEGG: son:SO3411 protease, putative YP_001184250.1 SMART: extracellular solute-binding protein, family 3; KEGG: son:SO3412 extracellular solute-binding proteins, family 3 protein YP_001184251.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001184252.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001184253.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001184254.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO3417 peptidyl-prolyl cis-trans isomerase SlyD YP_001184255.1 TIGRFAM: trp operon repressor; PFAM: Trp repressor; KEGG: son:SO3419 trp operon repressor YP_001184256.1 PFAM: cytochrome c, class II; KEGG: shm:Shewmr7_1205 cytochrome c, class II YP_001184257.1 PFAM: cytochrome B561; KEGG: she:Shewmr4_1133 cytochrome b561 YP_001184258.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: shm:Shewmr7_1203 sigma 54 modulation protein/ribosomal protein S30EA YP_001184259.1 PFAM: DNA polymerase III chi subunit, HolC; KEGG: she:Shewmr4_1131 DNA polymerase III chi subunit, HolC YP_001184260.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001184261.1 affects carbohydrate metabolism; has regulatory role in many processes YP_001184262.1 KEGG: shm:Shewmr7_1199 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase YP_001184263.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001184264.1 PFAM: regulatory protein RecX; KEGG: shm:Shewmr7_1197 regulatory protein RecX YP_001184265.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001184266.1 This protein performs the mismatch recognition step during the DNA repair process YP_001184267.1 TIGRFAM: RNA polymerase sigma factor RpoS; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70 region 1.2; KEGG: son:SO3432 RNA polymerase sigma-38 factor YP_001184268.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; KEGG: shm:Shewmr7_1193 peptidase M23B YP_001184269.1 KEGG: son:SO3434 protein-L-isoaspartate O-methyltransferase; TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_001184270.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001184271.1 PFAM: tRNA pseudouridine synthase D, TruD; KEGG: shm:Shewmr7_1190 pseudouridylate synthase YP_001184272.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001184273.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001184274.1 PFAM: Septum formation initiator; KEGG: shm:Shewmr7_1187 septum formation initiator YP_001184275.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001184276.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001184277.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001184278.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis YP_001184279.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001184280.1 catalyzes the formation of tetrahydropteroyl-L-glutamate and methionine from L-homocysteine and 5-methyltetrahydropteroyltri-L-glutamate YP_001184281.1 KEGG: cps:CPS_1152 hypothetical protein YP_001184282.1 KEGG: eba:ebA5435 conserved hypothetical protein, probable DNA/RNA helicase YP_001184283.1 KEGG: son:SO3455 GTP pyrophosphokinase; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; RelA/SpoT domain protein YP_001184284.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_001184285.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_001184286.1 PFAM: protein of unknown function DUF416; KEGG: she:Shewmr4_1108 protein of unknown function DUF416 YP_001184287.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO3460 transcriptional regulator, LysR family YP_001184288.1 PFAM: Auxin Efflux Carrier; KEGG: shm:Shewmr7_1171 auxin efflux carrier YP_001184289.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: she:Shewmr4_1104 DNA repair protein RecN YP_001184290.1 PFAM: phosphatidylglycerophosphatase A; KEGG: shm:Shewmr7_1168 phosphatidylglycerophosphatase YP_001184291.1 KEGG: she:Shewmr4_1101 thiamine-monophosphate kinase; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein domain protein YP_001184292.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001184293.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001184294.1 PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; KEGG: shm:Shewmr7_1164 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_001184295.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001184296.1 KEGG: son:SO3469 riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase, zinc-binding; bifunctional deaminase-reductase domain protein YP_001184297.1 PFAM: ATP-cone domain protein; KEGG: shm:Shewmr7_1161 ribonucleotide reductase regulator NrdR-like protein YP_001184298.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001184299.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001184300.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_1157 transcriptional regulator, LysR family YP_001184301.1 PFAM: beta-lactamase domain protein; KEGG: son:SO3474 metallo-beta-lactamase family protein YP_001184302.1 KEGG: shm:Shewmr7_1155 putative protein-disulfide isomerase YP_001184303.1 KEGG: pfl:PFL_0312 hypothetical protein YP_001184304.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_1150 efflux transporter, RND family, MFP subunit YP_001184305.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_1149 acriflavin resistance protein YP_001184306.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_1082 drug resistance transporter, Bcr/CflA subfamily YP_001184307.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: son:SO3488 transcriptional regulator, AraC/XylS family YP_001184308.1 PFAM: protein of unknown function DUF88; KEGG: sdn:Sden_0372 protein of unknown function DUF88 YP_001184309.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_1074 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family YP_001184310.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_1073 efflux transporter, RND family, MFP subunit YP_001184311.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_1144 transcriptional regulator, TetR family YP_001184312.1 PFAM: OsmC family protein; KEGG: shm:Shewmr7_1143 OsmC family protein YP_001184313.1 KEGG: she:Shewmr4_1070 extracellular solute-binding protein, family 3 YP_001184314.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_1141 transcriptional regulator, LysR family YP_001184315.1 PFAM: adenylosuccinate synthetase; KEGG: shm:Shewmr7_1140 adenylosuccinate synthase YP_001184316.1 PFAM: response regulator receiver; CheW domain protein; KEGG: vpa:VPA0746 chemotaxis protein CheV YP_001184317.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_1139 thioesterase superfamily protein YP_001184318.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: she:Shewmr4_1066 diguanylate cyclase/phosphodiesterase YP_001184319.1 PFAM: HDOD; KEGG: shm:Shewmr7_1137 putative signal transduction protein YP_001184320.1 PFAM: peptidase U32; KEGG: son:SO1252 peptidase, U32 family YP_001184321.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_1135 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001184322.1 KEGG: shm:Shewmr7_1134 sterol-binding domain protein YP_001184323.1 PFAM: peptidase U32; KEGG: she:Shewmr4_1061 peptidase U32 YP_001184324.1 PFAM: peptidase U32; KEGG: son:SO1248 hypothetical peptidase YP_001184325.1 KEGG: she:Shewmr4_1059 hypothetical protein YP_001184326.1 PFAM: nucleoside recognition domain protein; KEGG: shm:Shewmr7_1129 nucleoside recognition domain protein YP_001184327.1 PFAM: metallophosphoesterase; KEGG: shm:Shewmr7_1122 metallophosphoesterase YP_001184328.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: shm:Shewmr7_1121 phospholipid/glycerol acyltransferase YP_001184329.1 PFAM: CBS domain containing protein; KEGG: shm:Shewmr7_1120 CBS domain containing protein YP_001184330.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: son:SO1236 xanthine/uracil permease family protein YP_001184331.1 PFAM: type IV pilus assembly PilZ; KEGG: shm:Shewmr7_1111 type IV pilus assembly PilZ YP_001184332.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001184333.1 PFAM: type IV pilus assembly PilZ; KEGG: she:Shewmr4_1044 type IV pilus assembly PilZ YP_001184334.1 KEGG: shm:Shewmr7_1108 alpha/beta hydrolase fold YP_001184335.1 KEGG: she:Shewmr4_1042 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase YP_001184336.1 KEGG: son:SO1222 membrane protein YP_001184337.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_001184338.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_001184339.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_001184340.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001184341.1 PFAM: nucleoside-specific channel-forming protein, Tsx; KEGG: shm:Shewmr7_1101 nucleoside-specific channel-forming protein, Tsx YP_001184342.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: shm:Shewmr7_1100 nucleoside transporter YP_001184343.1 PFAM: TatD-related deoxyribonuclease; KEGG: she:Shewmr4_1034 TatD-related deoxyribonuclease YP_001184344.1 KEGG: sfr:Sfri_0998 hypothetical protein YP_001184345.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001184346.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_001184347.1 KEGG: son:SO1209 polyribonucleotide nucleotidyltransferase; PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH, type 1, domain protein; SMART: KH domain protein YP_001184348.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: shm:Shewmr7_1095 diguanylate cyclase/phosphodiesterase YP_001184349.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001184350.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001184351.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001184352.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001184353.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001184354.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001184355.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: son:SO1201 preprotein translocase, SecG subunit YP_001184356.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001184357.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001184358.1 KEGG: shm:Shewmr7_1085 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase, DHPS YP_001184359.1 KEGG: she:Shewmr4_1019 ATP-dependent metalloprotease FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001184360.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_001184361.1 PFAM: protein of unknown function UPF0044; KEGG: shm:Shewmr7_1082 protein of unknown function UPF0044 YP_001184362.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001184363.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001184364.1 KEGG: son:SO1192 hypothetical protein YP_001184365.1 TIGRFAM: transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: son:SO1191 transcription elongation factor GreA YP_001184366.1 KEGG: shm:Shewmr7_1077 hypothetical protein YP_001184367.1 KEGG: shm:Shewmr7_1076 lysozyme YP_001184368.1 PFAM: PepSY-associated TM helix domain protein; KEGG: son:SO1188 hypothetical protein YP_001184369.1 KEGG: son:SO1187 hypothetical protein YP_001184370.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001184371.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001184372.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: shm:Shewmr7_1071 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family YP_001184373.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001184374.1 PFAM: PhoH family protein; KEGG: she:Shewmr4_1003 PhoH family protein YP_001184375.1 PFAM: protein of unknown function UPF0054; KEGG: she:Shewmr4_1002 protein of unknown function UPF0054 YP_001184376.1 PFAM: CBS domain containing protein; transporter-associated region; KEGG: shm:Shewmr7_1066 CBS domain containing protein YP_001184377.1 Transfers the fatty acyl group on membrane lipoproteins YP_001184378.1 KEGG: shm:Shewmr7_1064 methylation site containing protein YP_001184379.1 KEGG: sde:Sde_2848 histidine kinase YP_001184380.1 PFAM: protein of unknown function DUF1451; KEGG: shm:Shewmr7_1063 protein of unknown function DUF1451 YP_001184381.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001184382.1 PFAM: Rare lipoprotein B; KEGG: shm:Shewmr7_1061 rare lipoprotein B YP_001184383.1 KEGG: son:SO1172 DNA polymerase III delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta YP_001184384.1 KEGG: shm:Shewmr7_1059 nicotinate (nicotinamide) nucleotide adenylyltransferase; TIGRFAM: cytidyltransferase-related domain; nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase YP_001184385.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: shm:Shewmr7_1058 iojap-like protein YP_001184386.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001184387.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: shm:Shewmr7_1056 peptidoglycan glycosyltransferase YP_001184388.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: shm:Shewmr7_1055 rod shape-determining protein RodA YP_001184389.1 TIGRFAM: lytic murein transglycosylase B; KEGG: shm:Shewmr7_1054 lytic murein transglycosylase B YP_001184390.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; Sporulation domain protein; KEGG: she:Shewmr4_0988 rare lipoprotein A YP_001184391.1 PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: son:SO1164 D-alanyl-D-alanine carboxypeptidase YP_001184392.1 PFAM: protein of unknown function DUF493; KEGG: shm:Shewmr7_1051 protein of unknown function DUF493 YP_001184393.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001184394.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001184395.1 TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1160 ribosomal-protein-alanine acetyltransferase YP_001184396.1 KEGG: shm:Shewmr7_1047 hypothetical protein YP_001184397.1 PFAM: Ferritin, Dps family protein; KEGG: shm:Shewmr7_1046 ferritin, Dps family protein YP_001184398.1 PFAM: protein of unknown function DUF1624; KEGG: she:Shewmr4_0980 hypothetical protein YP_001184399.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_0979 TonB-dependent siderophore receptor YP_001184400.1 KEGG: shm:Shewmr7_1043 hypothetical protein YP_001184401.1 KEGG: son:SOA0063 ISSod8, transposase YP_001184402.1 KEGG: ddi:DDB0219841 hypothetical protein YP_001184404.1 PFAM: beta-lactamase domain protein; KEGG: dvu:DVU1700 metallo-beta-lactamase family protein YP_001184405.1 KEGG: sus:Acid_0787 conserved hypothetical protein YP_001184406.1 PFAM: metallophosphoesterase; KEGG: ppr:PBPRA0880 hypothetical protein YP_001184407.1 KEGG: dps:DP0404 hypothetical protein YP_001184410.1 PFAM: phage integrase family protein; KEGG: pcr:Pcryo_0912 phage integrase YP_001184411.1 KEGG: vvy:VV0261 hypothetical protein YP_001184412.1 KEGG: abo:ABO_1505 hypothetical protein YP_001184413.1 PFAM: phage integrase family protein; KEGG: pcr:Pcryo_0961 phage integrase YP_001184414.1 KEGG: pcr:Pcryo_0962 hypothetical protein YP_001184415.1 SMART: helix-turn-helix domain protein; KEGG: pol:Bpro_0373 transcriptional regulator, Cro/CI family YP_001184416.1 PFAM: phage integrase family protein; KEGG: sdn:Sden_0317 phage integrase YP_001184418.1 PFAM: Prophage CP4-57 regulatory; KEGG: cps:CPS_2017 hypothetical protein YP_001184419.1 KEGG: son:SO4260 hypothetical protein YP_001184420.1 KEGG: son:SO4261 hypothetical protein YP_001184422.1 KEGG: eca:ECA0367 putative DNA-binding protein YP_001184423.1 PFAM: protein of unknown function UPF0150; KEGG: plu:plu2506 hypothetical protein YP_001184424.1 PFAM: N-6 DNA methylase; KEGG: bxe:Bxe_A0224 type I restriction-modification system, M subunit YP_001184425.1 PFAM: restriction modification system DNA specificity domain; KEGG: pol:Bpro_1941 restriction endonuclease S subunits-like YP_001184426.1 PFAM: ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: psb:Psyr_3725 ATPas YP_001184427.1 KEGG: psb:Psyr_3724 hypothetical protein YP_001184428.1 KEGG: bxe:Bxe_A0222 type I site-specific deoxyribonuclease HsdR; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like YP_001184429.1 PFAM: helix-turn-helix domain protein YP_001184430.1 KEGG: neu:NE2436 hypothetical protein YP_001184431.1 KEGG: vvu:VV10402 predicted transcriptional regulator YP_001184432.1 PFAM: HipA domain protein; KEGG: vvy:VV0798 hypothetical protein YP_001184433.1 KEGG: she:Shewmr4_3199 hypothetical protein YP_001184434.1 PFAM: transposase, IS4 family protein; KEGG: shm:Shewmr7_3098 transposase, IS4 family protein YP_001184435.1 KEGG: she:Shewmr4_1704 hypothetical protein YP_001184436.1 SMART: von Willebrand factor, type A; KEGG: she:Shewmr4_1703 von Willebrand factor, type A YP_001184437.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: she:Shewmr4_1702 ATPase associated with various cellular activities, AAA_5 YP_001184438.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: she:Shewmr4_1701 sigma54 specific transcriptional regulator, fis family YP_001184440.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: pat:Patl_4103 methyltransferase type 12 YP_001184441.1 PFAM: SEC-C motif domain protein; KEGG: ppr:PBPRA1441 hypothetical protein YP_001184442.1 KEGG: shm:Shewmr7_1015 hypothetical protein YP_001184443.1 PFAM: 3'-5' exonuclease; KEGG: shm:Shewmr7_1014 3'-5' exonuclease YP_001184444.1 PFAM: protein of unknown function DUF808; KEGG: she:Shewmr4_0975 protein of unknown function DUF808 YP_001184445.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001184446.1 SMART: PUA domain containing protein; KEGG: son:SO1149 hypothetical SAM-dependent methyltransferase YP_001184447.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: she:Shewmr4_0969 endonuclease/exonuclease/phosphatase YP_001184448.1 KEGG: son:SO1146 hypothetical protein YP_001184449.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: son:SO1145 magnesium transporter YP_001184450.1 PFAM: chemotaxis sensory transducer; KEGG: son:SO1144 methyl-accepting chemotaxis protein YP_001184451.1 KEGG: son:SO1143 hypothetical protein YP_001184452.1 PFAM: pseudouridine synthase; KEGG: sfr:Sfri_3001 pseudouridine synthase YP_001184453.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001184454.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001184455.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001184456.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: she:Shewmr4_0963 peptidylprolyl isomerase, FKBP-type YP_001184457.1 PFAM: peptidase M48, Ste24p; KEGG: son:SO1137 hypothetical protein YP_001184458.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_0998 DEAD/DEAH box helicase domain protein YP_001184459.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_001184460.1 PFAM: aldehyde dehydrogenase; KEGG: ppu:PP_2488 succinic-semialdehyde dehydrogenase, putative YP_001184461.1 PFAM: periplasmic binding protein; KEGG: son:SO3709 ABC transporter, periplasmic substrate-binding protein, putative YP_001184462.1 KEGG: shm:Shewmr7_3175 hypothetical protein YP_001184463.1 PFAM: GCN5-related N-acetyltransferase; KEGG: hch:HCH_04843 histone acetyltransferase HPA2/related acetyltransferase YP_001184466.1 KEGG: vvy:VV1846 hypothetical protein YP_001184467.1 KEGG: plu:plu1148 hypothetical protein YP_001184468.1 KEGG: son:SOA0150 hypothetical protein YP_001184470.1 KEGG: son:SO0729 hypothetical protein YP_001184471.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001184472.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_001184473.1 PFAM: cobalbumin biosynthesis enzyme; KEGG: shm:Shewmr7_3178 cobalbumin biosynthesis enzyme YP_001184474.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_001184475.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001184476.1 PFAM: transport system permease protein; KEGG: she:Shewmr4_0841 transport system permease protein YP_001184477.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO1033 iron-compound ABC transporter, ATP-binding protein, putative YP_001184478.1 PFAM: Phosphoglycerate mutase; KEGG: she:Shewmr4_0839 phosphoglycerate mutase YP_001184479.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_001184482.1 KEGG: mes:Meso_0922 hypothetical protein YP_001184483.1 KEGG: pfo:Pfl_4766 chemotaxis sensory transducer, PAS/Pac sensor; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001184484.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001184485.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001184486.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: she:Shewmr4_0956 protein of unknown function DUF6, transmembrane YP_001184487.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: son:SO1124 conserved hypothetical protein TIGR00011 YP_001184488.1 KEGG: she:Shewmr4_0954 hypothetical protein YP_001184489.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001184490.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001184491.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: shm:Shewmr7_0989 xanthine/uracil/vitamin C permease YP_001184492.1 KEGG: son:SO3679 hypothetical protein YP_001184493.1 KEGG: she:Shewmr4_0876 extracellular solute-binding protein, family 3 YP_001184494.1 PFAM: UspA domain protein; KEGG: shm:Shewmr7_3148 UspA domain protein YP_001184495.1 KEGG: she:Shewmr4_0873 hypothetical protein YP_001184496.1 PFAM: aldehyde dehydrogenase; KEGG: shm:Shewmr7_3150 aldehyde dehydrogenase YP_001184497.1 PFAM: regulatory protein, TetR; KEGG: she:Shewmr4_0871 transcriptional regulator, TetR family YP_001184498.1 PFAM: Curli production assembly/transport component CsgG; KEGG: shm:Shewmr7_3152 curli production assembly/transport component CsgG YP_001184499.1 KEGG: she:Shewmr4_0869 curli production assembly/transport component CsgF, putative YP_001184500.1 KEGG: she:Shewmr4_0868 curli production assembly/transport component CsgE, putative YP_001184501.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO3688 nitrogen regulation protein NtrY, putative YP_001184502.1 PFAM: protein of unknown function DUF214; KEGG: sdn:Sden_2848 protein of unknown function DUF214 YP_001184503.1 PFAM: protein of unknown function DUF214; KEGG: sdn:Sden_2849 protein of unknown function DUF214 YP_001184504.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_3159 ABC transporter related YP_001184505.1 KEGG: shm:Shewmr7_3160 hypothetical protein YP_001184506.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: she:Shewmr4_0861 efflux transporter, RND family, MFP subunit YP_001184507.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001184508.1 KEGG: son:SO3696 hypothetical protein YP_001184509.1 KEGG: shm:Shewmr7_3165 hypothetical protein YP_001184510.1 KEGG: sdn:Sden_1048 hypothetical protein YP_001184512.1 KEGG: zmo:ZMO1197 glutamate racemase; TIGRFAM: glutamate racemase; PFAM: Asp/Glu racemase YP_001184513.1 KEGG: she:Shewmr4_0079 MORN variant repeat protein YP_001184514.1 PFAM: GCN5-related N-acetyltransferase; KEGG: mxa:MXAN_1748 acetyltransferase, GNAT family YP_001184515.1 PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: rxy:Rxyl_0136 transcriptional regulator, GntR family YP_001184516.1 KEGG: son:SO3708 hypothetical protein YP_001184517.1 PFAM: Abortive infection protein; KEGG: pat:Patl_0909 hypothetical protein YP_001184518.1 PFAM: dienelactone hydrolase; KEGG: son:SO1006 dienelactone hydrolase family protein YP_001184519.1 KEGG: sdn:Sden_3091 hypothetical protein YP_001184520.1 TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_0943 uncharacterized domain 1 YP_001184521.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: she:Shewmr4_3033 endonuclease/exonuclease/phosphatase YP_001184522.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type; KEGG: she:Shewmr4_3034 peptidylprolyl isomerase, FKBP-type YP_001184523.1 PFAM: WD-40 repeat protein; KEGG: son:SO1064 hypothetical WD domain protein YP_001184524.1 PFAM: SlyX family protein; KEGG: she:Shewmr4_3036 SlyX family protein YP_001184525.1 KEGG: she:Shewmr4_3037 peptide deformylase; TIGRFAM: peptide deformylase; PFAM: formylmethionine deformylase YP_001184526.1 PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: son:SO1061 TPR domain protein YP_001184527.1 TIGRFAM: membrane lipoprotein lipid attachment site; KEGG: shm:Shewmr7_0935 hypothetical protein YP_001184528.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: shm:Shewmr7_0932 aminopeptidase N YP_001184529.1 PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_3042 methyl-accepting chemotaxis sensory transducer YP_001184530.1 KEGG: shm:Shewmr7_0929 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001184531.1 PFAM: protein of unknown function DUF72; KEGG: shm:Shewmr7_0928 protein of unknown function DUF72 YP_001184532.1 PFAM: phosphate transporter; KEGG: shm:Shewmr7_0927 phosphate transporter YP_001184533.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_001184534.1 PFAM: carbon starvation protein CstA; KEGG: shm:Shewmr7_0925 carbon starvation protein CstA YP_001184535.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1049 acetyltransferase, GNAT family YP_001184536.1 PFAM: LrgB family protein; KEGG: shm:Shewmr7_0923 LrgB family protein YP_001184537.1 PFAM: LrgA family protein; KEGG: shm:Shewmr7_0922 LrgA family protein YP_001184538.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO1046 transcriptional regulator, LysR family YP_001184539.1 PFAM: extracellular solute-binding protein, family 3; KEGG: shm:Shewmr7_0919 extracellular solute-binding protein, family 3 YP_001184540.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO1043 amino acid ABC transporter, permease protein YP_001184541.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_0917 ABC transporter related YP_001184543.1 KEGG: pfl:PFL_3339 hypothetical protein YP_001184544.1 KEGG: rba:RB954 hypothetical protein YP_001184545.1 KEGG: son:SO1508 hypothetical protein YP_001184546.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive YP_001184547.1 PFAM: heat shock protein DnaJ domain protein; KEGG: shm:Shewmr7_0910 heat shock protein DnaJ domain protein YP_001184548.1 PFAM: DSBA oxidoreductase; KEGG: shm:Shewmr7_0909 DsbA oxidoreductase YP_001184549.1 KEGG: son:SO3719 hypothetical protein YP_001184550.1 KEGG: shm:Shewmr7_0906 protoporphyrinogen oxidase YP_001184551.1 KEGG: shm:Shewmr7_0904 hypothetical protein YP_001184552.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_001184553.1 PFAM: Citrate transporter; TrkA-C domain protein; KEGG: shm:Shewmr7_0902 TrkA-C domain protein YP_001184554.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_001184555.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001184556.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: shm:Shewmr7_0899 uroporphyrin-III C-methyltransferase YP_001184557.1 PFAM: phospholipase A1; KEGG: shm:Shewmr7_0898 phospholipase A(1) YP_001184558.1 PFAM: peptidase S41; KEGG: she:Shewmr4_3075 hypothetical protein YP_001184559.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_001184560.1 KEGG: son:SO0994 hypothetical protein YP_001184561.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001184562.1 TIGRFAM: peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein; KEGG: shm:Shewmr7_3197 peptide chain release factor 2 YP_001184563.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: shm:Shewmr7_3198 formate dehydrogenase, alpha subunit YP_001184564.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: shm:Shewmr7_3199 methyl-accepting chemotaxis sensory transducer YP_001184565.1 TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter; KEGG: she:Shewmr4_0823 chromate transporter, chromate ion transporter (CHR) family YP_001184566.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_001184567.1 PFAM: FAD dependent oxidoreductase; KEGG: shm:Shewmr7_3207 FAD dependent oxidoreductase YP_001184568.1 PFAM: regulatory protein, MarR; KEGG: she:Shewmr4_0815 transcriptional regulator, MarR family YP_001184569.1 PFAM: OsmC family protein; KEGG: shm:Shewmr7_3209 OsmC family protein YP_001184570.1 KEGG: son:SO0975 hypothetical protein YP_001184571.1 KEGG: shm:Shewmr7_3211 hypothetical protein YP_001184572.1 KEGG: son:SO3733 hypothetical protein YP_001184573.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_001184574.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_001184575.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_001184576.1 TIGRFAM: sulfite reductase [NADPH] flavoprotein, alpha chain; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; flavodoxin/nitric oxide synthase; KEGG: she:Shewmr4_3080 sulfite reductase (NADPH) flavoprotein, alpha chain YP_001184577.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_001184578.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_001184579.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_0888 transcriptional regulator, TetR family YP_001184580.1 KEGG: son:SO3744 hypothetical protein YP_001184581.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_001184582.1 TIGRFAM: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; PFAM: lipid A biosynthesis acyltransferase; KEGG: son:SO3746 lipid A biosynthesis lauroyl acyltransferase YP_001184583.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_001184584.1 KEGG: shm:Shewmr7_0883 putative nitric oxide reductase (subunit B) transmembrane protein YP_001184585.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_001184586.1 PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: son:SO3748 LysM domain protein YP_001184587.1 KEGG: shm:Shewmr7_0880 hypothetical protein YP_001184588.1 PFAM: AFG1-family ATPase; KEGG: she:Shewmr4_3102 AFG1-family ATPase YP_001184589.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: psb:Psyr_2051 response regulator receiver:transcriptional regulatory protein, C-terminal YP_001184590.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Osmosensitive K+ channel His kinase sensor; KEGG: xom:XOO_3621 two-component system sensor protein YP_001184591.1 KEGG: pfo:Pfl_3155 hypothetical protein YP_001184592.1 KEGG: mca:MCA2215 K+-transporting ATPase, C subunit; TIGRFAM: potassium-transporting ATPase, C subunit; PFAM: K+ transporting ATPase, KdpC subunit YP_001184593.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; K+-transporting ATPase, B subunit; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: xcb:XC_3531 potassium-transporting ATPase B chain YP_001184594.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001184595.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO3757 rubisco operon transcriptional regulator YP_001184596.1 PFAM: protein of unknown function DUF897; KEGG: she:Shewmr4_3107 protein of unknown function DUF897 YP_001184597.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: shm:Shewmr7_0864 diguanylate cyclase with GAF sensor YP_001184598.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001184599.1 KEGG: she:Shewmr4_3110 hypothetical protein YP_001184600.1 KEGG: shm:Shewmr7_0861 protein of unknown function DUF350 YP_001184601.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001184602.1 KEGG: shm:Shewmr7_0859 hypothetical protein YP_001184603.1 PFAM: PspA/IM30 family protein; KEGG: son:SO3765 hypothetical protein YP_001184604.1 KEGG: son:SO3766 hypothetical protein YP_001184605.1 KEGG: shm:Shewmr7_0856 hypothetical protein YP_001184606.1 PFAM: Ion transport protein; Ion transport 2 domain protein,; KEGG: son:SO3768 ion transporter YP_001184607.1 PFAM: adenylate cyclase; KEGG: she:Shewmr4_3118 adenylate cyclase YP_001184608.1 PFAM: protein of unknown function DUF47; KEGG: shm:Shewmr7_0853 protein of unknown function DUF47 YP_001184609.1 PFAM: phosphate transporter; KEGG: she:Shewmr4_3120 phosphate transporter YP_001184610.1 PFAM: SH3, type 3 domain protein; SMART: SH3 domain protein domain protein; KEGG: shm:Shewmr7_0851 SH3 domain protein domain protein YP_001184611.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain YP_001184614.1 PFAM: protein of unknown function DUF599; KEGG: son:SO3776 hypothetical protein YP_001184615.1 KEGG: son:SO3777 hypothetical protein YP_001184616.1 TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: son:SO3778 adenylate cyclase CyaB, putative YP_001184617.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001184618.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001184619.1 KEGG: shm:Shewmr7_0839 hypothetical protein YP_001184620.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO3783 ATP-dependent RNA helicase, DEAD box family YP_001184621.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; KEGG: pen:PSEEN3931 aerotaxis receptor YP_001184622.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_001184623.1 PFAM: Pirin domain protein domain protein; Pirin domain protein; KEGG: she:Shewmr4_0744 pirin domain protein domain protein YP_001184624.1 KEGG: son:SO2169.1 hypothetical protein YP_001184625.1 KEGG: she:Shewmr4_2555 protein of unknown function DUF1568 YP_001184627.1 KEGG: sdn:Sden_3177 hypothetical protein YP_001184628.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0885 ABC transporter, ATP-binding protein YP_001184629.1 KEGG: shm:Shewmr7_3282 hypothetical protein YP_001184630.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: son:SO0883 hypothetical protein YP_001184631.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: son:SO0882 oxidoreductase, GMC family YP_001184632.1 KEGG: son:SO0881 hypothetical protein YP_001184633.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO0880 hypothetical protein YP_001184634.1 KEGG: shm:Shewmr7_3287 protein of unknown function UPF0270 YP_001184635.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: shm:Shewmr7_3288 phosphoribulokinase YP_001184636.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO0877 acetyltransferase, GNAT family YP_001184637.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_001184638.1 Regulatory factor involved in maltose metabolism YP_001184639.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger, DksA/TraR C4-type; KEGG: shm:Shewmr7_3292 transcriptional regulators, TraR/DksA family YP_001184640.1 PFAM: glutamyl-tRNA synthetase, class Ic; KEGG: shm:Shewmr7_3293 glutamyl-tRNA synthetase, class Ic YP_001184641.1 TIGRFAM: poly(A) polymerase; PFAM: Polynucleotide adenylyltransferase region; KEGG: she:Shewmr4_0728 poly(A) polymerase YP_001184642.1 KEGG: son:SO0871 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK YP_001184643.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001184644.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001184645.1 KEGG: she:Shewmr4_0724 hypothetical protein YP_001184646.1 PFAM: Curlin associated repeat protein; KEGG: son:SO0866 minor curlin subunit CsgB, putative YP_001184647.1 PFAM: Curlin associated repeat protein; KEGG: she:Shewmr4_0721 curlin associated repeat protein YP_001184648.1 PFAM: regulatory protein, LuxR; KEGG: she:Shewmr4_0720 transcriptional regulator, LuxR family YP_001184649.1 KEGG: she:Shewmr4_0719 hypothetical protein YP_001184650.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001184651.1 PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: son:SO0861 hypothetical protein YP_001184652.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: shm:Shewmr7_3306 response regulator receiver modulated metal dependent phosphohydrolase YP_001184653.1 KEGG: shm:Shewmr7_3307 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001184654.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: she:Shewmr4_0714 amino acid carrier protein YP_001184655.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_3309 ABC transporter related YP_001184656.1 PFAM: protein of unknown function DUF214; KEGG: son:SO0856 putative ABC transport system permease protein YP_001184657.1 KEGG: she:Shewmr4_0711 hypothetical protein YP_001184658.1 PFAM: NapD family protein; KEGG: son:SO0849 napD protein YP_001184659.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001184660.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway YP_001184661.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA YP_001184662.1 PFAM: Nitrate reductase cytochrome c-type subunit (NapB); KEGG: shm:Shewmr7_3321 nitrate reductase cytochrome c-type subunit (NapB) YP_001184663.1 KEGG: shm:Shewmr7_3322 hypothetical protein YP_001184664.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_3323 transcriptional regulator, LysR family YP_001184665.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001184666.1 PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: son:SO0840 acetyl-CoA carboxylase multifunctional enzyme accADC, carboxyl transferase subunit alpha/carboxyl transferase subunit beta/biotin carboxylase YP_001184667.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_0695 transcriptional regulator, LysR family YP_001184668.1 PFAM: penicillin-binding protein, transpeptidase; KEGG: son:SO0837 beta-lactamase, putative YP_001184669.1 KEGG: she:Shewmr4_0693 hypothetical protein YP_001184670.1 PFAM: protein of unknown function DUF335, SprT; SMART: protein of unknown function SprT; KEGG: son:SO0834 sprT protein, putative YP_001184671.1 PFAM: Endonuclease I; KEGG: she:Shewmr4_0691 deoxyribonuclease I YP_001184672.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001184673.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001184674.1 PFAM: Alkaline phosphatase; KEGG: shm:Shewmr7_3334 alkaline phosphatase YP_001184675.1 PFAM: methyltransferase small; Methyltransferase small, N-terminal domain protein; KEGG: she:Shewmr4_0687 rRNA (guanine-N(2)-)-methyltransferase YP_001184676.1 PFAM: protein of unknown function DUF342; KEGG: she:Shewmr4_3273 protein of unknown function DUF342 YP_001184677.1 KEGG: she:Shewmr4_3274 hypothetical protein YP_001184678.1 PFAM: peptidase M50; KEGG: shm:Shewmr7_0672 peptidase M50 YP_001184679.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: dvu:DVU0416 GGDEF domain protein YP_001184680.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: son:SO0822 outer membrane efflux family protein YP_001184681.1 PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: son:SO0821 ABC transporter, ATP-binding/permease protein YP_001184682.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: sugar-specific permease, EIIA 1 domain; secretion protein HlyD family protein; KEGG: son:SO0820 HlyD family secretion protein YP_001184683.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001184684.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_0653 transcriptional regulator, LysR family YP_001184685.1 PFAM: HDOD; KEGG: shm:Shewmr7_0652 putative signal transduction protein YP_001184686.1 KEGG: sfr:Sfri_1031 hypothetical protein YP_001184687.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_0651 TonB-dependent siderophore receptor YP_001184688.1 KEGG: son:SO0813 hypothetical protein YP_001184689.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific YP_001184690.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_001184691.1 TIGRFAM: Azurin; PFAM: blue (type 1) copper domain protein; KEGG: shm:Shewmr7_0645 blue (type 1) copper domain protein YP_001184692.1 KEGG: sdn:Sden_0953 hypothetical protein YP_001184693.1 KEGG: she:Shewmr4_3309 hypothetical protein YP_001184694.1 KEGG: shm:Shewmr7_0642 hypoxanthine-guanine phosphoribosyltransferase YP_001184695.1 PFAM: Alkaline phosphatase; KEGG: she:Shewmr4_3312 twin-arginine translocation pathway signal YP_001184696.1 PFAM: CBS domain containing protein; KEGG: shm:Shewmr7_0640 CBS domain containing membrane protein YP_001184697.1 KEGG: son:SO0804 hypothetical protein YP_001184698.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: shm:Shewmr7_0638 MATE efflux family protein YP_001184699.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: shm:Shewmr7_0637 alpha/beta hydrolase fold-3 domain protein YP_001184700.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001184701.1 PFAM: protein of unknown function DUF985; KEGG: shm:Shewmr7_0636 protein of unknown function DUF985 YP_001184702.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_3318 TonB-dependent receptor YP_001184703.1 KEGG: she:Shewmr4_3319 hypothetical protein YP_001184704.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: eba:ebA609 putative cation transport ATPase YP_001184705.1 KEGG: rpa:RPA2334 hypothetical protein YP_001184706.1 KEGG: rpa:RPA2335 hypothetical protein YP_001184708.1 KEGG: eba:ebB16 hypothetical protein YP_001184709.1 KEGG: eba:ebA616 hypothetical protein YP_001184710.1 TIGRFAM: uncharacterized domain; PFAM: OsmC family protein; protein of unknown function DUF181; KEGG: shm:Shewmr7_0632 uncharacterized domain YP_001184711.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: shm:Shewmr7_3199 methyl-accepting chemotaxis sensory transducer YP_001184712.1 KEGG: cps:CPS_2516 hypothetical protein YP_001184713.1 KEGG: son:SO0792 hypothetical protein YP_001184714.1 KEGG: son:SO0788 hypothetical protein YP_001184715.1 KEGG: pen:PSEEN2314 hypothetical protein YP_001184716.1 KEGG: son:SO0784 hypothetical protein YP_001184717.1 KEGG: mbu:Mbur_1645 ATPase YP_001184718.1 KEGG: syf:Synpcc7942_0180 hypothetical protein YP_001184720.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001184721.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001184722.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001184723.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: son:SO0778 oxidoreductase, FAD-binding, UbiH/Coq6 family YP_001184724.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; 2-polyprenyl-6-methoxyphenol 4-hydroxylase; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: she:Shewmr4_3333 2-polyprenyl-6-methoxyphenol 4-hydroxylase YP_001184725.1 TIGRFAM: yecA family protein; PFAM: protein of unknown function UPF0149; KEGG: shm:Shewmr7_0619 YecA family protein YP_001184726.1 PFAM: protein of unknown function DUF710; KEGG: son:SO0775 hypothetical protein YP_001184727.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: she:Shewmr4_3336 5-formyltetrahydrofolate cyclo-ligase YP_001184728.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: son:SO0772 oxidoreductase, short chain dehydrogenase/reductase family YP_001184729.1 PFAM: putative thiol-disulphide oxidoreductase DCC; KEGG: son:SO0771 hypothetical protein YP_001184730.1 oxidizes malate to oxaloacetate YP_001184731.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_001184732.1 PFAM: NAD-dependent epimerase/dehydratase; NmrA family protein; KEGG: shm:Shewmr7_0612 NAD-dependent epimerase/dehydratase YP_001184733.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_0611 transcriptional regulator, LysR family YP_001184734.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: son:SO0740 melanin biosynthesis protein TyrA, putative YP_001184735.1 KEGG: shm:Shewmr7_0609 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_001184736.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_0608 ABC transporter related YP_001184737.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: son:SO0743 iron(III) ABC transporter, permease protein YP_001184738.1 PFAM: extracellular solute-binding protein, family 1; KEGG: son:SO0744 iron(III) ABC transporter, periplasmic iron(III)-binding protein YP_001184739.1 KEGG: shm:Shewmr7_0605 hypothetical protein YP_001184740.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: shm:Shewmr7_0604 glutathione S-transferase, N-terminal domain protein YP_001184741.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: son:SO0747 ferredoxin--NADP reductase YP_001184742.1 KEGG: son:SO0748 hypothetical protein YP_001184743.1 PFAM: Phosphoglycerate mutase; KEGG: son:SO0749 hypothetical protein YP_001184744.1 PFAM: ferredoxin-dependent glutamate synthase; KEGG: shm:Shewmr7_0600 ferredoxin-dependent glutamate synthase YP_001184745.1 KEGG: son:SO0752 hypothetical protein YP_001184746.1 KEGG: shm:Shewmr7_0598 hypothetical protein YP_001184747.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0754 ABC transporter, ATP-binding protein YP_001184748.1 KEGG: shm:Shewmr7_0596 hypothetical protein YP_001184749.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001184750.1 KEGG: shm:Shewmr7_0593 hypothetical protein YP_001184751.1 PFAM: Rh family protein/ammonium transporter; KEGG: shm:Shewmr7_0592 Rh family protein/ammonium transporter YP_001184752.1 PFAM: nitrogen regulatory protein P-II; KEGG: son:SO0761 nitrogen regulatory protein P-II 1 YP_001184753.1 PFAM: isochorismatase hydrolase; KEGG: she:Shewmr4_3363 isochorismatase hydrolase YP_001184754.1 KEGG: shm:Shewmr7_0573 hypothetical protein YP_001184755.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: bbr:BB1960 hypothetical protein YP_001184756.1 PFAM: FxsA cytoplasmic membrane protein; KEGG: shm:Shewmr7_0548 FxsA cytoplasmic membrane protein YP_001184757.1 PFAM: CutA1 divalent ion tolerance protein; KEGG: shm:Shewmr7_0547 CutA1 divalent ion tolerance protein YP_001184758.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_001184759.1 PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: son:SO0695 glutathione-regulated potassium-efflux system protein KefC, putative YP_001184760.1 KEGG: she:Shewmr4_3408 galactokinase; TIGRFAM: galactokinase; PFAM: GHMP kinase; GHMP kinase, C terminal domain protein YP_001184761.1 PFAM: Aldose 1-epimerase; KEGG: son:SO0693 aldose 1-epimerase YP_001184762.1 KEGG: son:SO0691 hypothetical protein YP_001184763.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: son:SO0640 alcohol dehydrogenase, zinc-containing YP_001184764.1 KEGG: son:SO4013 hypothetical protein YP_001184765.1 PFAM: acriflavin resistance protein; KEGG: son:SO4014 AcrB/AcrD/AcrF family protein YP_001184766.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO4015 hypothetical protein YP_001184767.1 PFAM: protein kinase; leucine-rich repeat protein; SMART: tyrosine protein kinase; serine/threonine protein kinase; leucine-rich repeat-containing protein, typical subtype; KEGG: son:SO4016 hypothetical protein YP_001184768.1 PFAM: Peptidoglycan-binding LysM; Lytic transglycosylase, catalytic; MLTD_N domain protein; KEGG: son:SO4017 transglycosylase, Slt family YP_001184769.1 KEGG: she:Shewmr4_3415 hypothetical protein YP_001184770.1 KEGG: son:SO4019 hypothetical protein YP_001184771.1 PFAM: GCN5-related N-acetyltransferase; KEGG: vfi:VFA0653 IAA acetyltransferase YP_001184772.1 KEGG: son:SO4020 transcriptional regulator, LysR family YP_001184773.1 PFAM: peptidase M16 domain protein; KEGG: son:SO4022 peptidase, M16 family YP_001184775.1 KEGG: wsu:WS1457 hypothetical protein YP_001184776.1 PFAM: protein of unknown function DUF1566; KEGG: pat:Patl_3291 protein of unknown function DUF1566 YP_001184777.1 PFAM: protein of unknown function DUF1566; KEGG: pat:Patl_3291 protein of unknown function DUF1566 YP_001184778.1 PFAM: PKD domain containing protein; protein of unknown function DUF1566; KEGG: pat:Patl_3292 protein of unknown function DUF1566 YP_001184779.1 KEGG: mhu:Mhun_1163 PKD YP_001184780.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: cvi:CV0964 hypothetical protein YP_001184781.1 PFAM: helix-turn-helix- domain containing protein, AraC type; response regulator receiver; KEGG: cps:CPS_0756 sensory box sensor histidine kinase/DNA-binding response regulator, AraC family YP_001184782.1 KEGG: she:Shewmr4_3418 hypothetical protein YP_001184783.1 PFAM: Stringent starvation protein B; KEGG: shm:Shewmr7_3424 stringent starvation protein B YP_001184784.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_001184785.1 PFAM: cytochrome c1; KEGG: shm:Shewmr7_3426 cytochrome c1 YP_001184786.1 PFAM: Cytochrome b/b6, N-terminal domain; Cytochrome b/b6, C-terminal domain; KEGG: son:SO0609 ubiquinol-cytochrome c reductase, cytochrome b YP_001184787.1 KEGG: shm:Shewmr7_3428 ubiquinol-cytochrome c reductase, iron-sulfur subunit; TIGRFAM: ubiquinol-cytochrome c reductase, iron-sulfur subunit; PFAM: Rieske [2Fe-2S] domain protein YP_001184788.1 TIGRFAM: HflC protein; PFAM: band 7 protein; KEGG: shm:Shewmr7_3429 HflC protein YP_001184789.1 TIGRFAM: HflK protein; PFAM: band 7 protein; KEGG: she:Shewmr4_0600 HflK protein YP_001184790.1 PFAM: GTP-binding protein, HSR1-related; KEGG: son:SO0604 GTP-binding protein HflX YP_001184791.1 TIGRFAM: RNA chaperone Hfq; PFAM: Like-Sm ribonucleoprotein, core; KEGG: shm:Shewmr7_3432 RNA chaperone Hfq YP_001184792.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001184793.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001184794.1 PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: she:Shewmr4_0595 N-acetylmuramoyl-L-alanine amidase YP_001184795.1 PFAM: protein of unknown function UPF0079; KEGG: son:SO0599 conserved hypothetical protein TIGR00150 YP_001184796.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family N-terminal domain protein; KEGG: she:Shewmr4_0593 carbohydrate kinase, YjeF related protein YP_001184797.1 KEGG: shm:Shewmr7_3438 hypothetical protein YP_001184798.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001184799.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001184800.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_001184801.1 PFAM: protein of unknown function DUF6, transmembrane; UAA transporter; KEGG: shm:Shewmr7_3442 protein of unknown function DUF6, transmembrane YP_001184802.1 PFAM: MscS Mechanosensitive ion channel; KEGG: she:Shewmr4_0587 MscS mechanosensitive ion channel YP_001184803.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: shm:Shewmr7_3444 glycerophosphoryl diester phosphodiesterase YP_001184804.1 KEGG: shm:Shewmr7_3445 hypothetical protein YP_001184805.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; KEGG: shm:Shewmr7_3447 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor YP_001184806.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: she:Shewmr4_0582 BFD domain protein (2Fe-2S)-binding domain protein YP_001184807.1 catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide YP_001184808.1 KEGG: she:Shewmr4_0580 hypothetical protein YP_001184809.1 PFAM: protein kinase; SMART: serine/threonine protein kinase; KEGG: shm:Shewmr7_3451 serine/threonine protein kinase YP_001184810.1 KEGG: son:SO0578 hypothetical protein YP_001184811.1 KEGG: she:Shewmr4_0577 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Cache domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001184812.1 PFAM: PhoH family protein; SMART: AAA ATPase; Nucleotide binding protein, PINc; KEGG: shm:Shewmr7_3454 PhoH family protein YP_001184813.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_001184814.1 KEGG: son:SO0573 hypothetical protein YP_001184815.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001184816.1 PFAM: response regulator receiver; KEGG: son:SO0570 response regulator YP_001184817.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_3459 diguanylate cyclase YP_001184818.1 PFAM: protein of unknown function DUF1260; KEGG: son:SO0568 hypothetical protein YP_001184819.1 KEGG: she:Shewmr4_0569 1-acyl-sn-glycerol-3-phosphate acyltransferases; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; PFAM: phospholipid/glycerol acyltransferase YP_001184820.1 PFAM: ABC-3 protein; KEGG: shm:Shewmr7_3462 ABC-3 protein YP_001184821.1 PFAM: periplasmic solute binding protein; KEGG: shm:Shewmr7_3463 periplasmic solute binding protein YP_001184822.1 KEGG: shm:Shewmr7_3464 hypothetical protein YP_001184823.1 KEGG: shm:Shewmr7_3465 hypothetical protein YP_001184824.1 KEGG: she:Shewmr4_0564 hypothetical protein YP_001184825.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_001184826.1 PFAM: MaoC domain protein dehydratase; KEGG: son:SO0559 MaoC domain protein YP_001184827.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: son:SO0558 smtA protein YP_001184828.1 PFAM: GumN family protein; KEGG: son:SO0557 hypothetical protein YP_001184829.1 KEGG: shm:Shewmr7_3474 hypothetical protein YP_001184830.1 PFAM: GGDEF domain containing protein; CBS domain containing protein; EAL domain protein; KEGG: shm:Shewmr7_3475 diguanylate cyclase/phosphodiesterase YP_001184831.1 KEGG: shm:Shewmr7_3476 hypothetical protein YP_001184832.1 KEGG: shm:Shewmr7_3477 hypothetical protein YP_001184833.1 KEGG: shm:Shewmr7_3479 hypothetical protein YP_001184834.1 KEGG: son:SO0550 hypothetical protein YP_001184835.1 PFAM: response regulator receiver; KEGG: shm:Shewmr7_3481 response regulator receiver protein YP_001184836.1 PFAM: histone family protein DNA-binding protein; KEGG: she:Shewmr4_0548 histone family protein DNA-binding protein YP_001184837.1 KEGG: she:Shewmr4_0547 hypothetical protein YP_001184838.1 TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: son:SO0546 ribosomal protein S6 modification protein YP_001184839.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; KEGG: son:SO0545 response regulator YP_001184840.1 PFAM: response regulator receiver; KEGG: she:Shewmr4_0544 response regulator receiver protein YP_001184841.1 KEGG: she:Shewmr4_0543 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; CHASE domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001184842.1 KEGG: shm:Shewmr7_3488 hypothetical protein YP_001184843.1 PFAM: protein of unknown function DUF1704; KEGG: son:SO0542 hypothetical protein YP_001184844.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: sdn:Sden_0649 amino acid carrier protein YP_001184845.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: son:SO0541 metallo-beta-lactamase family protein YP_001184846.1 KEGG: son:SO0540 hypothetical protein YP_001184847.1 KEGG: shm:Shewmr7_3496 redox-active disulfide protein 2 YP_001184848.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: son:SO0527 hypothetical protein YP_001184849.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_0525 GCN5-related N-acetyltransferase YP_001184850.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_001184851.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: son:SO0521 hypothetical protein YP_001184852.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_3513 heavy metal efflux pump, CzcA family YP_001184853.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO0519 cation efflux protein, putative YP_001184854.1 KEGG: shm:Shewmr7_3515 outer membrane efflux protein YP_001184855.1 KEGG: she:Shewmr4_0515 hypothetical protein YP_001184856.1 KEGG: shm:Shewmr7_3517 hypothetical protein YP_001184857.1 KEGG: son:SO0514 hypothetical protein YP_001184858.1 PFAM: Class I peptide chain release factor; KEGG: son:SO0513 hypothetical protein YP_001184859.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001184860.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: shm:Shewmr7_3522 short-chain dehydrogenase/reductase SDR YP_001184862.1 KEGG: she:Shewmr4_0507 hypothetical protein YP_001184863.1 TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: shm:Shewmr7_3525 UbiD family decarboxylases YP_001184864.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_001184866.1 KEGG: she:Shewmr4_0502 conserved hypothetical flavoprotein oxygenase YP_001184867.1 PFAM: transcriptional regulator domain protein; KEGG: shm:Shewmr7_3532 transcriptional regulator, CadC YP_001184868.1 KEGG: son:SO0488 copper ABC transporter, permease protein YP_001184869.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: son:SO0487 copper ABC transporter, ATP-binding protein YP_001184870.1 PFAM: periplasmic copper-binding; SMART: Parallel beta-helix repeat; Carbohydrate-binding and sugar hydrolysis; KEGG: son:SO0486 copper ABC transporter, periplasmic copper-binding protein YP_001184871.1 PFAM: NosL family protein; KEGG: son:SO0485 NosL protein YP_001184872.1 KEGG: son:SO0482 formate-dependent nitrite reductase, NrfG protein YP_001184873.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type; KEGG: she:Shewmr4_0490 FKBP-type peptidyl-prolyl isomerase domain protein YP_001184874.1 SMART: Rhodanese domain protein; KEGG: shm:Shewmr7_3541 rhodanese domain protein YP_001184875.1 KEGG: she:Shewmr4_0488 cytochrome c, putative YP_001184876.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: son:SO0478 cytochrome c-type biogenesis protein CcmF YP_001184877.1 PFAM: cytochrome C biogenesis protein; KEGG: shm:Shewmr7_3544 cytochrome c biogenesis protein YP_001184878.1 PFAM: Redoxin domain protein; KEGG: shm:Shewmr7_3545 redoxin domain protein YP_001184879.1 KEGG: son:SO0474 hypothetical protein YP_001184880.1 KEGG: shm:Shewmr7_3550 putative mitomycin resistance protein YP_001184881.1 PFAM: protein of unknown function UPF0118; KEGG: she:Shewmr4_0479 protein of unknown function UPF0118 YP_001184882.1 PFAM: 2-nitropropane dioxygenase, NPD; KEGG: she:Shewmr4_0476 2-nitropropane dioxygenase, NPD YP_001184883.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_001184884.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_001184885.1 KEGG: pst:PSPTO_0021 hypothetical protein YP_001184886.1 PFAM: SNF2-related protein; helicase domain protein; type III restriction enzyme, res subunit; SMART: DEAD-like helicases-like; KEGG: pst:PSPTO_0017 helicase/SNF2 family domain protein YP_001184887.1 KEGG: psb:Psyr_3988 hypothetical protein YP_001184888.1 PFAM: NUDIX hydrolase; KEGG: son:SO0464 MutT/nudix family protein YP_001184889.1 PFAM: protein of unknown function DUF853, NPT hydrolase putative; KEGG: shm:Shewmr7_3566 protein of unknown function DUF853, NPT hydrolase putative YP_001184890.1 KEGG: shm:Shewmr7_3567 hypothetical protein YP_001184891.1 TIGRFAM: TRAP transporter solute receptor, TAXI family; KEGG: she:Shewmr4_0461 TRAP transporter solute receptor, TAXI family YP_001184892.1 TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: she:Shewmr4_0460 TRAP transporter, 4TM/12TM fusion protein YP_001184893.1 KEGG: she:Shewmr4_0459 hypothetical protein YP_001184894.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: shm:Shewmr7_2789 regulatory protein GntR, HTH YP_001184895.1 PFAM: outer membrane porin; KEGG: shm:Shewmr7_2788 outer membrane porin YP_001184896.1 PFAM: Tannase and feruloyl esterase; KEGG: sfr:Sfri_3696 feruloyl esterase YP_001184897.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: sfr:Sfri_3694 twin-arginine translocation pathway signal YP_001184898.1 KEGG: shm:Shewmr7_2786 hypothetical protein YP_001184900.1 KEGG: she:Shewmr4_0458 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein YP_001184901.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO0453 peptidyl-prolyl cis-trans isomerase FkbP YP_001184902.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: son:SO0452 thioredoxin 2 YP_001184903.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: she:Shewmr4_0455 anion transporter YP_001184904.1 PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_0452 major facilitator superfamily MFS_1 YP_001184905.1 PFAM: PepSY-associated TM helix domain protein; KEGG: shm:Shewmr7_3578 PepSY-associated TM helix domain protein YP_001184906.1 KEGG: son:SO0448 hypothetical protein YP_001184907.1 KEGG: son:SO0447 hypothetical protein YP_001184908.1 PFAM: band 7 protein; KEGG: shm:Shewmr7_3581 band 7 protein YP_001184909.1 PFAM: permease; KEGG: son:SO0444 hypothetical protein YP_001184910.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_001184911.1 involved in de novo purine biosynthesis YP_001184912.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001184913.1 KEGG: shm:Shewmr7_3587 hypothetical protein YP_001184914.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_3588 short-chain dehydrogenase/reductase SDR YP_001184915.1 KEGG: son:SO0437 sensory box protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001184916.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001184918.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_001184919.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001184920.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_001184921.1 KEGG: son:SO0430 hypothetical protein YP_001184922.1 PFAM: peptidase M13, neprilysin; peptidase M13; KEGG: son:SO0429 peptidase, M13 family YP_001184923.1 PFAM: surface antigen (D15); Patatin; KEGG: she:Shewmr4_0432 patatin YP_001184924.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001184925.1 KEGG: son:SO0425 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001184926.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001184927.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_001184928.1 involved in regulation of beta-lactamase; putative signaling protein YP_001184929.1 PFAM: N-acetylmuramoyl-L-alanine amidase, family 2; KEGG: son:SO0421 AmpD protein YP_001184930.1 KEGG: shm:Shewmr7_3603 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase YP_001184931.1 PFAM: Fimbrial protein pilin; KEGG: dar:Daro_3356 fimbrial protein pilin:bacterial general secretion pathway protein H YP_001184932.1 TIGRFAM: type IV-A pilus assembly ATPase PilB; PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; KEGG: son:SO0416 type IV pilus biogenesis protein PilB YP_001184933.1 PFAM: type II secretion system protein; KEGG: shm:Shewmr7_3606 type II secretion system protein YP_001184934.1 PFAM: peptidase A24A, prepilin type IV; peptidase A24A domain protein; KEGG: son:SO0414 leader peptidase (prepilin peptidase) / N-methyltransferase YP_001184935.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001184936.1 PFAM: protein of unknown function DUF1342; KEGG: she:Shewmr4_0416 protein of unknown function DUF1342 YP_001184937.1 PFAM: protein of unknown function DUF329; KEGG: shm:Shewmr7_3610 protein of unknown function DUF329 YP_001184938.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: she:Shewmr4_0414 mutator MutT protein YP_001184939.1 KEGG: shm:Shewmr7_3612 hypothetical protein YP_001184940.1 PFAM: Ppx/GppA phosphatase; KEGG: shm:Shewmr7_3613 Ppx/GppA phosphatase YP_001184941.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_001184942.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: shm:Shewmr7_3615 thioredoxin YP_001184943.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001184944.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_0408 transcriptional regulator, LysR family YP_001184945.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: shm:Shewmr7_3618 NADPH:quinone reductase YP_001184946.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: she:Shewmr4_0406 antibiotic biosynthesis monooxygenase YP_001184947.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001184948.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001184949.1 PFAM: fumarate reductase respiratory complex, transmembrane subunit; KEGG: she:Shewmr4_0403 fumarate reductase respiratory complex, transmembrane subunit YP_001184950.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit YP_001184951.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001184952.1 TIGRFAM: putative TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase, DuS; dihydroorotate dehydrogenase; KEGG: son:SO0394 tRNA-dihydrouridine synthase B YP_001184953.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_001184954.1 KEGG: sdn:Sden_3629 hypothetical protein YP_001184955.1 PFAM: type IV pilus assembly PilZ; KEGG: sdn:Sden_3630 type IV pilus assembly PilZ YP_001184956.1 PFAM: OmpA/MotB domain protein; KEGG: sdn:Sden_3631 OmpA/MotB YP_001184957.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: sdn:Sden_3632 MotA/TolQ/ExbB proton channel YP_001184958.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001184959.1 PFAM: flagellar basal body-associated protein FliL; KEGG: sdn:Sden_3634 flagellar basal body-associated protein FliL YP_001184960.1 PFAM: flagellar hook-length control protein; KEGG: sdn:Sden_3635 flagellar hook-length control protein YP_001184961.1 KEGG: sdn:Sden_3636 hypothetical protein YP_001184962.1 PFAM: flagellar protein FliS; KEGG: sdn:Sden_3637 flagellar protein FliS YP_001184963.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; KEGG: sdn:Sden_3638 flagellar hook-associated 2-like protein YP_001184964.1 PFAM: flagellin domain protein; KEGG: sdn:Sden_3639 flagellin-like protein YP_001184965.1 PFAM: flagellin domain protein; KEGG: sdn:Sden_3639 flagellin-like protein YP_001184966.1 KEGG: sdn:Sden_3640 hypothetical protein YP_001184967.1 TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: sdn:Sden_3641 flagellin-like protein YP_001184968.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; KEGG: sdn:Sden_3642 flagellar hook-associated protein YP_001184969.1 FlgJ; flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; like the lateral flagella FlgJ in Vibrio parahaemolyticus this protein does not contains a C-terminal muramidase domain YP_001184970.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001184971.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_001184972.1 TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: sdn:Sden_3646 flagellar basal-body rod FlgG YP_001184973.1 TIGRFAM: flagellar basal-body rod protein FlgF; PFAM: flagellar basal body rod protein; KEGG: sdn:Sden_3647 flagellar basal-body rod FlgF YP_001184974.1 the hook connects flagellar basal body to the flagellar filament; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001184975.1 PFAM: flagellar hook capping protein; KEGG: sdn:Sden_3649 flagellar hook capping protein YP_001184976.1 TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: protein of unknown function DUF1078 domain protein; KEGG: sdn:Sden_3650 flagellar basal-body rod protein FlgC YP_001184977.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001184978.1 PFAM: SAF domain; KEGG: sdn:Sden_3652 flageller protein FlgA YP_001184979.1 KEGG: sdn:Sden_3653 hypothetical protein YP_001184980.1 KEGG: sdn:Sden_3654 hypothetical protein YP_001184981.1 KEGG: sdn:Sden_3655 hypothetical protein YP_001184982.1 KEGG: sdn:Sden_3656 ATPase FliI/YscN; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; H+-transporting two-sector ATPase, alpha/beta subunit domain protein; SMART: AAA ATPase YP_001184983.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001184984.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001184985.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; the Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001184986.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: sdn:Sden_3660 flagellar hook-basal body complex protein (FliE) YP_001184987.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: sdn:Sden_3661 sigma-54 factor, interaction region YP_001184988.1 KEGG: sdn:Sden_3662 hypothetical protein YP_001184989.1 TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; KEGG: sdn:Sden_3663 surface presentation of antigens (SpoA) protein YP_001184990.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001184991.1 TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ, family 3; KEGG: sdn:Sden_3665 export protein FliQ, family 3 YP_001184992.1 TIGRFAM: flagellar biosynthetic protein FliR; PFAM: type III secretion system inner membrane R protein; KEGG: sdn:Sden_3666 flagellar biosynthetic protein FliR YP_001184993.1 TIGRFAM: flagellar biosynthetic protein FlhB; PFAM: type III secretion exporter; KEGG: sdn:Sden_3667 flagellar biosynthetic protein FlhB YP_001184994.1 TIGRFAM: flagellar biosynthesis protein FlhA; PFAM: type III secretion FHIPEP protein; KEGG: sdn:Sden_3668 flagellar biosynthesis protein FlhA YP_001184995.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: son:SO4295 NAD(P)H dehydrogenase (quinone) YP_001184996.1 PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: son:SO4296 NupC family protein YP_001184997.1 PFAM: purine and other phosphorylases, family 1; KEGG: son:SO4297 uridine phosphorylase, putative YP_001184998.1 PFAM: cyclic nucleotide-binding; KEGG: son:SO4298 cyclic nucleotide binding protein, putative YP_001184999.1 PFAM: peptidase M16 domain protein; KEGG: shm:Shewmr7_3815 peptidase M16 domain protein YP_001185000.1 PFAM: peptidase M16 domain protein; KEGG: shm:Shewmr7_3814 peptidase M16 domain protein YP_001185001.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: son:SO4537 peptidase, putative YP_001185002.1 KEGG: she:Shewmr4_3739 hypothetical protein YP_001185003.1 KEGG: she:Shewmr4_0329 hypothetical protein YP_001185004.1 KEGG: she:Shewmr4_0915 hypothetical protein YP_001185006.1 TIGRFAM: RNA methyltransferase, TrmH family, group 2; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: shm:Shewmr7_3807 RNA methyltransferase, TrmH family, group 2 YP_001185007.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: shm:Shewmr7_3806 protein of unknown function DUF6, transmembrane YP_001185008.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_3805 transcriptional regulator, LysR family YP_001185009.1 PFAM: Patatin; KEGG: shm:Shewmr7_3804 patatin YP_001185010.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO4524 transcriptional regulator, LysR family YP_001185011.1 IrgA; binds ferric enterobactin; irgA gene expression is repressed by Fur and induced by the divergently transcribed upstream gene irgB; outer membrane protein; involved in iron metabolism YP_001185012.1 KEGG: son:SO4522 hypothetical protein YP_001185013.1 KEGG: she:Shewmr4_3731 hypothetical protein YP_001185014.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001185015.1 PFAM: Bile acid:sodium symporter; KEGG: shm:Shewmr7_3800 bile acid:sodium symporter YP_001185016.1 PFAM: RNP-1 like RNA-binding protein; KEGG: shm:Shewmr7_0175 RNP-1 like RNA-binding protein YP_001185017.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001185018.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_001185019.1 KEGG: son:SO4497 ISSod5, transposase YP_001185021.1 KEGG: vfi:VFA0515 transposase YP_001185022.1 PFAM: plasmid stabilization system; KEGG: son:SO1444 hypothetical protein YP_001185023.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: shm:Shewmr7_1769 transcriptional regulator, CopG family YP_001185024.1 KEGG: shm:Shewmr7_1770 retinol acyltransferase domain protein YP_001185025.1 PFAM: phage integrase family protein; KEGG: ilo:IL0646 integrase/recombinase, XerC/XerD family YP_001185026.1 KEGG: shm:Shewmr7_1773 hypothetical protein YP_001185027.1 PFAM: YagBYeeUYfjZ family protein; KEGG: son:SO1453 hypothetical protein YP_001185028.1 KEGG: she:Shewmr4_1698 hypothetical protein YP_001185029.1 PFAM: DNA repair protein RadC; KEGG: shm:Shewmr7_1776 DNA repair protein RadC YP_001185030.1 PFAM: Prophage CP4-57 regulatory; KEGG: shm:Shewmr7_1777 phage transcriptional regulator, AlpA YP_001185031.1 PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like; KEGG: ngo:NGO0697 putative type I restriction enzyme YP_001185032.1 PFAM: N-6 DNA methylase; KEGG: ngo:NGO0702 type I restriction enzyme M protein YP_001185033.1 PFAM: restriction modification system DNA specificity domain; KEGG: mba:Mbar_A2665 type I restriction-modification system specificity subunit YP_001185034.1 KEGG: ngo:NGO0700 hypothetical protein YP_001185035.1 KEGG: ngo:NGO0701 hypothetical protein YP_001185036.1 KEGG: neu:NE1363 hypothetical protein YP_001185037.1 PFAM: Appr-1-p processing domain protein; KEGG: neu:NE1364 Appr-1-p processing enzyme family YP_001185038.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: she:Shewmr4_2154 alcohol dehydrogenase, zinc-binding domain protein YP_001185039.1 KEGG: she:Shewmr4_2148 putative transcriptional regulator, TetR family YP_001185040.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2226 transcriptional regulator, LysR family YP_001185041.1 KEGG: shm:Shewmr7_2227 hypothetical protein YP_001185042.1 KEGG: shm:Shewmr7_2228 hypothetical protein YP_001185043.1 KEGG: shm:Shewmr7_2229 tetraheme cytochrome c YP_001185044.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: shm:Shewmr7_2230 flavocytochrome c YP_001185045.1 KEGG: eca:ECA2856 hypothetical protein YP_001185046.1 PFAM: helix-turn-helix domain protein; KEGG: ava:Ava_2195 transcriptional regulator, XRE family YP_001185047.1 KEGG: vvy:VV1846 hypothetical protein YP_001185048.1 PFAM: phage integrase family protein; KEGG: lpn:lpg1070 integrase, phage related YP_001185049.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_001185050.1 PFAM: fatty acid desaturase; KEGG: son:SO0197 fatty acid desaturase, family 1 YP_001185051.1 catalyzes the formation of selenophosphate from selenide and ATP YP_001185052.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_001185053.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: son:SO0194 acyltransferase family protein YP_001185054.1 PFAM: regulatory protein, TetR; KEGG: she:Shewmr4_0172 transcriptional regulator, TetR family YP_001185055.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_0166 GCN5-related N-acetyltransferase YP_001185056.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: shm:Shewmr7_0165 3'(2'),5'-bisphosphate nucleotidase YP_001185057.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001185058.1 PFAM: Fibronectin, type III domain protein; Ig family protein; SMART: Dystroglycan-type cadherin domain protein; KEGG: son:SO0189 fibronectin type III domain protein YP_001185059.1 PFAM: phage Tail Collar domain protein; KEGG: sdn:Sden_3729 phage tail collar YP_001185060.1 PFAM: GCN5-related N-acetyltransferase; KEGG: hch:HCH_06057 acetyltransferase YP_001185061.1 KEGG: son:SO0181 hypothetical protein YP_001185062.1 PFAM: Phytanoyl-CoA dioxygenase; KEGG: son:SO0180 hypothetical protein YP_001185063.1 PFAM: Aspartyl/Asparaginyl beta-hydroxylase; KEGG: son:SO0179 hypothetical protein YP_001185064.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_0162 HAD-superfamily hydrolase, subfamily IA, variant 3 YP_001185065.1 PFAM: type II secretion system protein N; KEGG: shm:Shewmr7_0161 type II secretion system protein N YP_001185066.1 PFAM: General secretion pathway M protein; KEGG: son:SO0175 general secretion pathway protein M YP_001185067.1 TIGRFAM: general secretion pathway protein L; PFAM: General secretion pathway L; KEGG: she:Shewmr4_0164 general secretion pathway protein L YP_001185068.1 PFAM: General secretion pathway protein K; KEGG: she:Shewmr4_0163 general secretion pathway protein K YP_001185069.1 TIGRFAM: general secretion pathway protein J; KEGG: son:SO0172 general secretion pathway protein J YP_001185070.1 TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: shm:Shewmr7_0156 general secretion pathway protein I YP_001185071.1 TIGRFAM: general secretion pathway protein H; KEGG: son:SO0170 general secretion pathway protein H YP_001185072.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: shm:Shewmr7_0154 general secretion pathway protein G YP_001185073.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein; KEGG: son:SO0168 general secretion pathway protein F YP_001185074.1 KEGG: shm:Shewmr7_0152 general secretion pathway protein E; TIGRFAM: general secretion pathway protein E; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001185075.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: son:SO0166 general secretion pathway protein D YP_001185076.1 TIGRFAM: general secretion pathway protein C; KEGG: she:Shewmr4_0155 general secretion pathway protein C YP_001185077.1 PFAM: RNA-binding S4 domain protein; KEGG: shm:Shewmr7_0149 RNA-binding S4 domain protein YP_001185078.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001185079.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001185080.1 KEGG: tde:TDE0520 hypothetical protein YP_001185082.1 KEGG: son:SOA0067 hypothetical protein YP_001185083.1 PFAM: protein of unknown function DUF542, ScdA domain protein; Hemerythrin HHE cation binding domain protein; KEGG: she:Shewmr4_0398 hemerythrin HHE cation binding domain protein YP_001185084.1 PFAM: AAA-4 family protein; KEGG: shm:Shewmr7_3628 putative transcriptional regulator YP_001185085.1 PFAM: HupE/UreJ protein; KEGG: she:Shewmr4_0396 HupE/UreJ protein YP_001185086.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: she:Shewmr4_0395 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_001185087.1 TIGRFAM: tyrosine recombinase XerC; PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: son:SO4306 integrase/recombinase XerC YP_001185088.1 PFAM: protein of unknown function DUF484; KEGG: shm:Shewmr7_3632 protein of unknown function DUF484 YP_001185089.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001185090.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: shm:Shewmr7_3634 diaminopimelate decarboxylase YP_001185091.1 KEGG: shm:Shewmr7_3635 hypothetical protein YP_001185092.1 PFAM: Frataxin family protein; KEGG: shm:Shewmr7_3636 frataxin family protein YP_001185093.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_001185094.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001185095.1 PFAM: Uroporphyrinogen III synthase HEM4; KEGG: son:SO4314 uroporphyrinogen-III synthase YP_001185096.1 PFAM: protein of unknown function DUF513, hemX; KEGG: shm:Shewmr7_3640 protein of unknown function DUF513, HemX YP_001185097.1 PFAM: HemY domain protein; KEGG: she:Shewmr4_0385 HemY domain protein YP_001185098.1 KEGG: shm:Shewmr7_3642 putative outer membrane adhesin like protein; TIGRFAM: putative outer membrane adhesin like proteiin; PFAM: Hemolysin-type calcium-binding region; TMP repeat-containing protein; SMART: Cadherin YP_001185099.1 PFAM: ABC transporter, transmembrane region; ABC transporter related; peptidase C39, bacteriocin processing; SMART: AAA ATPase; KEGG: she:Shewmr4_0383 ABC transporter related YP_001185100.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_3644 type I secretion membrane fusion protein, HlyD family YP_001185101.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: shm:Shewmr7_3645 type I secretion outer membrane protein, TolC family YP_001185102.1 PFAM: OmpA/MotB domain protein; KEGG: she:Shewmr4_0380 OmpA/MotB domain protein YP_001185103.1 KEGG: shm:Shewmr7_3647 hypothetical protein YP_001185104.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: shm:Shewmr7_3648 diguanylate cyclase/phosphodiesterase YP_001185105.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: she:Shewmr4_0377 diguanylate cyclase/phosphodiesterase with GAF sensor YP_001185106.1 TIGRFAM: ATP-dependent DNA helicase Rep; PFAM: UvrD/REP helicase; KEGG: she:Shewmr4_0376 ATP-dependent DNA helicase Rep YP_001185107.1 PFAM: protein of unknown function DUF526; KEGG: son:SO4329 hypothetical protein YP_001185108.1 KEGG: shm:Shewmr7_3652 hypothetical protein YP_001185109.1 KEGG: shm:Shewmr7_3653 hypothetical protein YP_001185110.1 PFAM: NnrS family protein; KEGG: sfr:Sfri_3037 NnrS family protein YP_001185111.1 PFAM: cytochrome c552; KEGG: sfr:Sfri_3036 nitrite reductase (cytochrome; ammonia-forming) YP_001185112.1 PFAM: Inner membrane CreD family protein; KEGG: shm:Shewmr7_3656 inner membrane CreD family protein YP_001185113.1 PFAM: phosphoesterase, PA-phosphatase related; KEGG: shm:Shewmr7_3657 phosphoesterase, PA-phosphatase related YP_001185114.1 PFAM: import inner membrane translocase, subunit Tim44; KEGG: son:SO4340 hypothetical protein YP_001185115.1 KEGG: bur:Bcep18194_B1335 hypothetical protein YP_001185117.1 PFAM: aminotransferase, class V; KEGG: son:SO4343 aminotransferase, class V YP_001185118.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_001185119.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001185120.1 PFAM: amino acid-binding ACT domain protein; KEGG: shm:Shewmr7_3663 acetolactate synthase small subunit YP_001185121.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_001185122.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001185123.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_001185124.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: shm:Shewmr7_3667 protein of unknown function DUF21 YP_001185125.1 PFAM: protein of unknown function UPF0153; KEGG: she:Shewmr4_0357 protein of unknown function UPF0153 YP_001185126.1 PFAM: ERCC4 domain protein; KEGG: sdn:Sden_0291 ERCC4 YP_001185127.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_001185128.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_0340 transcriptional regulator, LysR family YP_001185129.1 KEGG: shm:Shewmr7_0339 hypothetical protein YP_001185130.1 KEGG: shm:Shewmr7_0338 hypothetical protein YP_001185131.1 PFAM: helix-turn-helix domain protein; KEGG: shm:Shewmr7_0337 transcriptional regulator, XRE family YP_001185132.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: shm:Shewmr7_0336 filamentation induced by cAMP protein Fic YP_001185133.1 KEGG: son:SO0366 hypothetical protein YP_001185134.1 PFAM: aminoglycoside phosphotransferase; KEGG: shm:Shewmr7_0333 aminoglycoside phosphotransferase YP_001185135.1 KEGG: she:Shewmr4_3611 hypothetical protein YP_001185136.1 KEGG: shm:Shewmr7_0331 hypothetical protein YP_001185137.1 Essential for recycling GMP and indirectly, cGMP YP_001185138.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001185139.1 KEGG: son:SO0359 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; metal-dependent phosphohydrolase, HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase, HD region YP_001185140.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: son:SO0358 endoribonuclease L-PSP, putative YP_001185141.1 PFAM: AMP-dependent synthetase and ligase; KEGG: son:SO0355 AMP-binding protein YP_001185142.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: shm:Shewmr7_0325 Na+/Ca+ antiporter, CaCA family YP_001185143.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: hne:HNE_1653 TonB-dependent receptor YP_001185144.1 KEGG: shm:Shewmr7_0321 hypothetical protein YP_001185145.1 PFAM: superoxide dismutase, copper/zinc binding; KEGG: vch:VC1583 superoxide dismutase, Cu-Zn YP_001185146.1 KEGG: son:SO0349 magnesium chelatase family protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001185147.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: son:SO0348 acyltransferase family protein YP_001185148.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: she:Shewmr4_3626 phospholipid/glycerol acyltransferase YP_001185149.1 PFAM: protein of unknown function DUF523; KEGG: she:Shewmr4_3627 protein of unknown function DUF523 YP_001185150.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: shm:Shewmr7_0316 transcriptional regulator, GntR family YP_001185151.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_001185152.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_001185153.1 Catalyzes the conversion of citrate to isocitrate YP_001185154.1 TIGRFAM: putative AcnD-accessory protein PrpF; PFAM: protein of unknown function DUF453; KEGG: shm:Shewmr7_0312 putative AcnD-accessory protein PrpF YP_001185155.1 KEGG: shm:Shewmr7_0311 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; Two component regulator three Y domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001185156.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001185157.1 PFAM: Modulator of Rho-dependent transcription termination; KEGG: shm:Shewmr7_0308 transcriptional antiterminator, Rof YP_001185158.1 KEGG: son:SO0338 hypothetical protein YP_001185159.1 PFAM: Endoribonuclease L-PSP; KEGG: son:SO0337 hypothetical translation initiation inhibitor, YjgF family YP_001185160.1 PFAM: Na+/H+ antiporter NhaC; KEGG: she:Shewmr4_3639 Na+/H+ antiporter NhaC YP_001185161.1 PFAM: protein of unknown function DUF904; KEGG: shm:Shewmr7_0304 protein of unknown function DUF904 YP_001185162.1 PFAM: protein of unknown function DUF1107; KEGG: son:SO0334 hypothetical protein YP_001185163.1 PFAM: DSBA oxidoreductase; KEGG: son:SO0333 thiol:disulfide interchange protein DsbA YP_001185164.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_001185165.1 KEGG: she:Shewmr4_3644 hypothetical protein YP_001185166.1 PFAM: protein of unknown function UPF0061; KEGG: she:Shewmr4_3645 protein of unknown function UPF0061 YP_001185167.1 KEGG: shm:Shewmr7_0298 hypothetical protein YP_001185168.1 KEGG: shm:Shewmr7_0297 hypothetical protein YP_001185169.1 PFAM: DsrE family protein; KEGG: shm:Shewmr7_0296 DsrE family protein YP_001185170.1 KEGG: shm:Shewmr7_0295 hypothetical protein YP_001185171.1 KEGG: she:Shewmr4_3650 hypothetical protein YP_001185172.1 KEGG: shm:Shewmr7_0293 hypothetical protein YP_001185173.1 PFAM: periplasmic binding protein; KEGG: ppu:PP_2591 ferric siderophore ABC transporter, periplasmic siderophore-binding protein YP_001185174.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pen:PSEEN2494 ferric siderophore ABC transporter, ATP-binding protein BauE YP_001185175.1 PFAM: transport system permease protein; KEGG: pen:PSEEN2495 ferric siderophore ABC transporter, permease protein BauC YP_001185176.1 PFAM: transport system permease protein; ABC-3 protein; KEGG: ppu:PP_2594 ferric siderophore ABC transporter, permease protein YP_001185177.1 KEGG: rha:RHA1_ro03859 probable tetracycline repressor YP_001185178.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: rru:Rru_A2312 TonB-dependent receptor YP_001185179.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bur:Bcep18194_B0675 ABC efflux pump, fused inner membrane and ATPase subunits YP_001185180.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: nfa:nfa28020 putative ABC transporter YP_001185181.1 KEGG: shm:Shewmr7_0292 hypothetical protein YP_001185182.1 PFAM: acyltransferase 3; KEGG: she:Shewmr4_3653 acyltransferase 3 YP_001185183.1 KEGG: she:Shewmr4_3654 hypothetical protein YP_001185184.1 PFAM: protein of unknown function DUF1232; KEGG: she:Shewmr4_3655 protein of unknown function DUF1232 YP_001185185.1 KEGG: shm:Shewmr7_0279 hypothetical protein YP_001185186.1 PFAM: Orn/Lys/Arg decarboxylase, major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: she:Shewmr4_3667 ornithine decarboxylase YP_001185187.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system YP_001185188.1 PFAM: porin, Gram-negative type; KEGG: she:Shewmr4_3669 porin, gram-negative type YP_001185189.1 PFAM: Radical SAM domain protein; Radical SAM N-terminal domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: son:SO0311 hypothetical Fe-S oxidoreductase YP_001185190.1 KEGG: shm:Shewmr7_0274 hypothetical protein YP_001185191.1 PFAM: protein of unknown function DUF1212; KEGG: son:SO0308 hypothetical protein YP_001185192.1 KEGG: she:Shewmr4_3673 hypothetical protein YP_001185193.1 PFAM: ThiJ/PfpI domain protein; KEGG: lbl:LBL_2610 transcriptional regulator, ThiJ/PfpI family protein YP_001185194.1 PFAM: regulatory protein, TetR; KEGG: btk:BT9727_2867 transcriptional regulator, TetR family YP_001185195.1 KEGG: sdn:Sden_0547 hypothetical protein YP_001185196.1 KEGG: sdn:Sden_0546 putative orphan protein YP_001185197.1 KEGG: sdn:Sden_0545 hypothetical protein YP_001185198.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: she:Shewmr4_3683 protein of unknown function UPF0011 YP_001185199.1 PFAM: LppC family lipoprotein; KEGG: she:Shewmr4_3684 LppC family lipoprotein YP_001185200.1 PFAM: protein of unknown function UPF0102; KEGG: shm:Shewmr7_0260 protein of unknown function UPF0102 YP_001185201.1 TIGRFAM: phosphoheptose isomerase; KEGG: shm:Shewmr7_0259 phosphoheptose isomerase YP_001185202.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria; KEGG: shm:Shewmr7_0258 transport-associated YP_001185203.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: shm:Shewmr7_0257 protein of unknown function DUF6, transmembrane YP_001185204.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_0256 transcriptional regulator, LysR family YP_001185205.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001185206.1 TIGRFAM: phosphoglycolate phosphatase ; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_0254 phosphoglycolate phosphatase YP_001185207.1 PFAM: ribulose-phosphate 3-epimerase; Orotidine 5'-phosphate decarboxylase; KEGG: shm:Shewmr7_0253 ribulose-phosphate 3-epimerase YP_001185208.1 KEGG: shm:Shewmr7_0252 hypothetical protein YP_001185209.1 KEGG: son:SO0290 hypothetical protein YP_001185210.1 KEGG: she:Shewmr4_3695 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_001185211.1 PFAM: Sporulation domain protein; KEGG: son:SO0288 DamX domain protein YP_001185212.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001185213.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001185214.1 TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; Secretin/TonB, short N-terminal domain; KEGG: she:Shewmr4_3699 type IV pilus secretin PilQ YP_001185215.1 PFAM: Pilus assembly protein, PilQ; KEGG: shm:Shewmr7_0245 pilus assembly protein, PilQ YP_001185216.1 PFAM: Pilus assembly protein, PilO; KEGG: shm:Shewmr7_0244 pilus assembly protein, PilO YP_001185217.1 PFAM: Fimbrial assembly family protein; KEGG: shm:Shewmr7_0243 fimbrial assembly family protein YP_001185218.1 TIGRFAM: type IV pilus assembly protein PilM; KEGG: son:SO0281 type IV pilus biogenesis protein PilM YP_001185219.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; KEGG: shm:Shewmr7_0241 penicillin-binding protein, 1A family YP_001185220.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001185221.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001185222.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001185223.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001185224.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001185225.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001185226.1 PFAM: protein of unknown function DUF1439; KEGG: shm:Shewmr7_0234 protein of unknown function DUF1439 YP_001185227.1 TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: son:SO0272 competence/damage-inducible protein CinA YP_001185228.1 PFAM: Redoxin domain protein; KEGG: shm:Shewmr7_0232 redoxin domain protein YP_001185229.1 PFAM: cytochrome C biogenesis protein; KEGG: son:SO0268 cytochrome c-type biogenesis protein CcmH YP_001185230.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: Redoxin domain protein; KEGG: son:SO0267 thiol:disulfide interchange protein DsbE YP_001185231.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: shm:Shewmr7_0229 cytochrome c-type biogenesis protein CcmF YP_001185232.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: son:SO0265 cytochrome c-type biogenesis protein CcmH YP_001185233.1 PFAM: cytochrome c, class I; KEGG: shm:Shewmr7_0227 cytochrome c, class I YP_001185234.1 ATP-binding protein; required for proper cytochrome c maturation YP_001185235.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: son:SO0262 heme exporter protein CcmB YP_001185236.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein; KEGG: son:SO0261 heme exporter protein CcmC YP_001185237.1 PFAM: Heme exporter protein D (CcmD); KEGG: shm:Shewmr7_0223 heme exporter protein D (CcmD) YP_001185238.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001185239.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001185240.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001185241.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001185242.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001185243.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001185244.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001185245.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001185246.1 late assembly protein YP_001185247.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001185248.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001185249.1 binds 5S rRNA along with protein L5 and L25 YP_001185250.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001185251.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001185252.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001185253.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001185254.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001185255.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001185256.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001185257.1 one of the stabilizing components for the large ribosomal subunit YP_001185258.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001185259.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001185260.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001185261.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001185262.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001185263.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001185264.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001185265.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001185266.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001185267.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001185268.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001185269.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001185270.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001185271.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001185272.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001185273.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001185274.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001185275.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001185276.1 binds directly to 23S ribosomal RNA YP_001185277.1 KEGG: shm:Shewmr7_0182 NusG antitermination factor; TIGRFAM: transcription termination/antitermination factor NusG; PFAM: transcription antitermination protein NusG; KOW domain protein; SMART: NGN domain protein; KOW (Kyrpides, Ouzounis, Woese) domain protein YP_001185278.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001185279.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001185280.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001185281.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001185282.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001185283.1 PFAM: ribonuclease T2; KEGG: son:SO4599 ribonuclease, T2 family YP_001185284.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter, transmembrane; KEGG: son:SO4601 tryptophan-specific transport protein YP_001185285.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_001185286.1 Represses a number of genes involved in the response to DNA damage YP_001185287.1 KEGG: she:Shewmr4_3790 hypothetical protein YP_001185288.1 PFAM: cytochrome c oxidase, subunit II; cytochrome c, class I; cytochrome C oxidase subunit II, transmembrane region; KEGG: she:Shewmr4_3791 cytochrome c oxidase, subunit II YP_001185289.1 PFAM: cytochrome c oxidase, subunit I; KEGG: shm:Shewmr7_3865 cytochrome-c oxidase YP_001185290.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_001185291.1 PFAM: cytochrome c oxidase, subunit III; KEGG: shm:Shewmr7_3867 cytochrome c oxidase, subunit III YP_001185292.1 KEGG: son:SO4611 hypothetical protein YP_001185293.1 KEGG: son:SO4612 hypothetical protein YP_001185294.1 PFAM: cytochrome oxidase assembly; KEGG: son:SO4613 cytochrome oxidase assembly protein, putative YP_001185295.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001185296.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; electron transport protein SCO1/SenC; KEGG: shm:Shewmr7_3873 electron transport protein SCO1/SenC YP_001185297.1 PFAM: polysaccharide deacetylase; KEGG: she:Shewmr4_3801 polysaccharide deacetylase YP_001185298.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO4617 DNA-damage-inducible protein F YP_001185299.1 KEGG: dsy:DSY0720 hypothetical protein YP_001185300.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_001185301.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FMN-binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: son:SO4620 fumarate reductase, flavoprotein subunit precursor YP_001185302.1 KEGG: son:SO4621 hypothetical protein YP_001185303.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4622 sensor histidine kinase YP_001185304.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO4623 DNA-binding response regulator YP_001185305.1 PFAM: regulatory protein, LuxR; KEGG: son:SO4624 transcriptional regulator, LuxR family YP_001185306.1 KEGG: son:SO4625 competence protein ComF YP_001185307.1 TIGRFAM: bioH protein; PFAM: alpha/beta hydrolase fold; KEGG: shm:Shewmr7_3882 BioH protein YP_001185308.1 KEGG: she:Shewmr4_3807 hypothetical protein YP_001185309.1 PFAM: sulfatase; KEGG: shm:Shewmr7_3884 sulfatase YP_001185310.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase, RNase H domain protein fold; KEGG: son:SO4629 hypothetical protein YP_001185311.1 PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: she:Shewmr4_3810 transcription elongation factor GreB YP_001185312.1 PFAM: phage integrase family protein; KEGG: shm:Shewmr7_3887 phage integrase family protein YP_001185313.1 KEGG: shm:Shewmr7_3888 phage integrase family protein YP_001185314.1 KEGG: shm:Shewmr7_3889 hypothetical protein YP_001185315.1 TIGRFAM: transcription elongation factor GreB; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: shm:Shewmr7_3890 transcription elongation factor GreB YP_001185316.1 KEGG: abo:ABO_1505 hypothetical protein YP_001185317.1 KEGG: son:SO4533 ISSod10, transposase OrfA YP_001185318.1 KEGG: hch:HCH_00506 hypothetical protein YP_001185319.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfr:Sfri_4001 major facilitator superfamily MFS_1 YP_001185320.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate YP_001185321.1 SMART: protein tyrosine phosphatase, catalytic region; KEGG: ppu:PP_1926 phosphatase family protein, putative YP_001185322.1 KEGG: cps:CPS_3356 redox-active disulfide protein 2 YP_001185323.1 PFAM: permease; KEGG: sfr:Sfri_1725 permease YP_001185324.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: son:SO0533 arsenate reductase, putative YP_001185325.1 PFAM: regulatory protein, ArsR; KEGG: son:SO0532 arsenical resistence operon repressor YP_001185326.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: sfr:Sfri_4004 transcriptional regulator, ArsR family protein YP_001185327.1 PFAM: regulatory protein, ArsR; KEGG: son:SO0502 transcriptional regulator, ArsR family YP_001185328.1 PFAM: permease; KEGG: son:SO0503 hypothetical protein YP_001185329.1 PFAM: glutathione synthase, ATP-binding; KEGG: vfi:VF0976 glutathione synthetase YP_001185330.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: dsy:DSY4609 putative oxidoreductase iron-sulfur subunit YP_001185331.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: dsy:DSY4131 putative anaerobic dehydrogenase YP_001185332.1 PFAM: Arsenical resistance operon trans-acting repressor ArsD; KEGG: dar:Daro_2638 arsenical resistance operon trans-acting repressor ArsD YP_001185333.1 KEGG: dar:Daro_2637 anion-transporting ATPase; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase; SMART: AAA ATPase YP_001185334.1 TIGRFAM: arsenical pump membrane protein; PFAM: Arsenical pump membrane protein; Citrate transporter; KEGG: sbo:SBO_3500 arsenical pump membrane protein YP_001185335.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: sbo:SBO_3501 arsenate reductase YP_001185336.1 PFAM: acriflavin resistance protein; KEGG: aeh:Mlg_0882 acriflavin resistance protein YP_001185337.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: xac:XAC2064 cation efflux system protein YP_001185338.1 PFAM: cytochrome c biogenesis protein, transmembrane region; KEGG: mhu:Mhun_0868 putative cytochrome c biogenesis protein YP_001185339.1 KEGG: mhu:Mhun_0869 hypothetical protein YP_001185340.1 TIGRFAM: redox-active disulfide protein 2; KEGG: plt:Plut_1705 redox-active disulfide protein 2 YP_001185341.1 PFAM: regulatory protein, ArsR; KEGG: dps:DP0944 similar to ArsR-family transcription regulator YP_001185342.1 PFAM: helix-turn-helix domain protein; KEGG: sfr:Sfri_3420 transcriptional regulator, XRE family protein YP_001185343.1 KEGG: sfr:Sfri_3419 hypothetical protein YP_001185344.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; KEGG: sfr:Sfri_3418 type III restriction enzyme, res subunit YP_001185345.1 KEGG: dar:Daro_2667 hypothetical protein YP_001185346.1 PFAM: Integrase, catalytic region; KEGG: vch:VCA0791 transposase OrfAB, subunit B YP_001185347.1 PFAM: transposase IS3/IS911 family protein; KEGG: vch:VCA0792 transposase OrfAB, subunit A YP_001185348.1 KEGG: dar:Daro_2669 hypothetical protein YP_001185349.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: bja:bll8094 hypothetical protein YP_001185350.1 PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: shm:Shewmr7_3901 GreA/GreB family elongation factor YP_001185351.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_001185352.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_001185353.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_3904 methyl-accepting chemotaxis sensory transducer YP_001185354.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shm:Shewmr7_3905 redoxin domain protein YP_001185355.1 KEGG: shm:Shewmr7_3906 hypothetical protein YP_001185356.1 PFAM: Propeptide, PepSY amd peptidase M4; KEGG: shm:Shewmr7_3907 propeptide, PepSY amd peptidase M4 YP_001185357.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO4647 DNA-binding response regulator YP_001185358.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO4648 sensor histidine kinase YP_001185359.1 KEGG: shm:Shewmr7_3910 hypothetical protein YP_001185360.1 KEGG: son:SO4656 hypothetical protein YP_001185361.1 KEGG: shm:Shewmr7_3912 diguanylate cyclase/phosphodiesterase with PAS/PAC and CHASE sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; CHASE domain protein; MASE1 domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001185362.1 KEGG: she:Shewmr4_3822 hypothetical protein YP_001185363.1 TIGRFAM: ubiquinol oxidase, subunit II; PFAM: cytochrome c oxidase, subunit II; COX aromatic rich domain protein; KEGG: she:Shewmr4_3823 ubiquinol oxidase, subunit II YP_001185364.1 PFAM: cytochrome c oxidase, subunit I; KEGG: shm:Shewmr7_3915 cytochrome-c oxidase YP_001185365.1 PFAM: cytochrome c oxidase, subunit III; KEGG: she:Shewmr4_3825 cytochrome c oxidase, subunit III YP_001185366.1 PFAM: cytochrome C oxidase subunit IV; KEGG: shm:Shewmr7_3917 cytochrome c oxidase subunit IV YP_001185367.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001185368.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_0950 TonB-dependent siderophore receptor YP_001185369.1 PFAM: amino acid permease-associated region; Amino acid transporter, transmembrane; KEGG: pmu:PM0162 arginine/ornithine antiporter, putative YP_001185370.1 PFAM: homocysteine S-methyltransferase; KEGG: ppu:PP_0658 homocysteine S-methyltransferase family protein YP_001185371.1 PFAM: helix-turn-helix domain protein; KEGG: shm:Shewmr7_3944 transcriptional regulator, XRE family YP_001185372.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001185373.1 PFAM: conserved hypothetical protein 698; KEGG: she:Shewmr4_3853 conserved hypothetical protein 698 YP_001185374.1 KEGG: shm:Shewmr7_3947 hypothetical protein YP_001185375.1 PFAM: Paraquat-inducible protein A; KEGG: shm:Shewmr7_3953 paraquat-inducible protein A YP_001185376.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: son:SO4711 HD domain protein YP_001185377.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: she:Shewmr4_3866 ABC transporter related YP_001185378.1 TIGRFAM: isochorismate synthases; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: she:Shewmr4_3868 isochorismate synthases YP_001185379.1 KEGG: she:Shewmr4_3869 hypothetical protein YP_001185380.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: son:SO4715 hypothetical protein YP_001185381.1 KEGG: she:Shewmr4_3871 acetyltransferase, GNAT family YP_001185382.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: shm:Shewmr7_3965 periplasmic sensor signal transduction histidine kinase YP_001185383.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_3966 two component, sigma54 specific, transcriptional regulator, fis family YP_001185384.1 PFAM: extracellular solute-binding protein, family 1; KEGG: she:Shewmr4_3874 extracellular solute-binding protein, family 1 YP_001185385.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_3968 binding-protein-dependent transport systems inner membrane component YP_001185386.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: shm:Shewmr7_3969 ABC transporter related YP_001185387.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein A; KEGG: shm:Shewmr7_3970 molybdopterin-guanine dinucleotide biosynthesis protein A YP_001185388.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin binding domain; molybdopterin-guanine dinucleotide biosynthesis MobB region; MoeA domain protein, domain I and II; MoeA domain protein, domain IV; KEGG: she:Shewmr4_3878 molybdopterin-guanine dinucleotide biosynthesis protein B YP_001185389.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001185390.1 KEGG: son:SO4725 hypothetical protein YP_001185391.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001185392.1 KEGG: shm:Shewmr7_3982 hypothetical protein YP_001185393.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001185394.1 PFAM: sulfatase; KEGG: vvu:VV10813 predicted hydrolase of alkaline phosphatase superfamily YP_001185395.1 KEGG: sbo:SBO_0865 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_001185396.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: sfr:Sfri_2828 dTDP-4-dehydrorhamnose reductase YP_001185397.1 PFAM: glycosyl transferase, family 2; KEGG: ppr:PBPRA0213 putative lipopolysaccharide biosynthesis glycosyltransferase YP_001185398.1 PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; KEGG: shm:Shewmr7_3986 CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase YP_001185399.1 PFAM: UDP-galactopyranose mutase; KEGG: atc:AGR_L_1762 probable UDP-galactopyranose mutase YP_001185400.1 KEGG: sme:SMb21065 hypothetical protein YP_001185401.1 PFAM: glycosyl transferase, family 25; KEGG: vpa:VP0210 putative Lex2B YP_001185402.1 PFAM: glycosyl transferase, family 9; KEGG: son:SO4678 heptosyl transferase, glycosyltransferase family 9 protein YP_001185403.1 catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position YP_001185404.1 PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain protein; KEGG: son:SO4676 3-deoxy-D-manno-octulosonic-acid (KDO) transferase YP_001185405.1 PFAM: regulatory protein, TetR; KEGG: son:SO4675 transcriptional regulator, TetR family YP_001185406.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_001185407.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_001185408.1 PFAM: Rhodanese domain protein; KEGG: shm:Shewmr7_3994 rhodanese domain protein YP_001185409.1 PFAM: Rhomboid family protein; KEGG: shm:Shewmr7_3995 rhomboid family protein YP_001185410.1 PFAM: ThiJ/PfpI domain protein; KEGG: son:SO4670 enhancing lycopene biosynthesis protein YP_001185411.1 KEGG: shm:Shewmr7_3997 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2 YP_001185412.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001185413.1 PFAM: cytochrome c, class I; KEGG: son:SO4666 cytochrome c YP_001185415.1 KEGG: son:SO4727 hypothetical protein YP_001185416.1 PFAM: protein of unknown function DUF414; KEGG: son:SO4728 hypothetical protein YP_001185417.1 KEGG: shm:Shewmr7_4002 hypothetical protein YP_001185418.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001185419.1 catalyzes the formation of inosine from adenosine YP_001185420.1 PFAM: protein of unknown function DUF885; KEGG: shm:Shewmr7_4005 protein of unknown function DUF885 YP_001185421.1 PFAM: alpha/beta hydrolase fold; KEGG: she:Shewmr4_3914 alpha/beta hydrolase fold YP_001185422.1 KEGG: shm:Shewmr7_4007 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; GGDEF domain containing protein; PAC repeat-containing protein YP_001185423.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4737 iron-sulfur cluster-binding protein YP_001185424.1 KEGG: she:Shewmr4_3917 hypothetical protein YP_001185425.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_001185426.1 KEGG: she:Shewmr4_3919 hypothetical protein YP_001185427.1 KEGG: rxy:Rxyl_1790 superfamily I DNA and RNA helicases and helicase subunits-like protein YP_001185428.1 PFAM: transposase IS3/IS911 family protein; KEGG: vpa:VP1788 putative transposase YP_001185429.1 PFAM: Integrase, catalytic region; KEGG: vpa:VP1787 putative transposase YP_001185431.1 KEGG: sth:STH2261 putative DNA modification methylase YP_001185432.1 PFAM: helix-turn-helix domain protein YP_001185435.1 KEGG: ssn:SSO_3895 transposition regulatory protein YP_001185436.1 KEGG: ssn:SSO_3894 transposition protein YP_001185439.1 SMART: AAA ATPase; KEGG: ssn:SSO_3893 ATP-binding protein YP_001185440.1 KEGG: ssn:SSO_3892 putative transposase YP_001185441.1 KEGG: eba:ebA515 hypothetical protein YP_001185442.1 KEGG: eba:ebA514 hypothetical protein YP_001185443.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: cte:CT1913 DNA methylase, putative YP_001185444.1 PFAM: Integrase, catalytic region; KEGG: son:SOA0151 ISSod13, transposase YP_001185445.1 KEGG: cte:CT1914 hypothetical protein YP_001185446.1 KEGG: cte:CT1915 hypothetical protein YP_001185447.1 KEGG: ilo:IL2609 transposon Tn7 transposition transposition regulatory protein TnsE YP_001185448.1 KEGG: ilo:IL2610 transposon Tn7 transposition protein TnsD YP_001185449.1 KEGG: ilo:IL2611 transposon Tn7 transposition protein TnsC YP_001185450.1 PFAM: Integrase, catalytic region; KEGG: ilo:IL2612 transposon Tn7 transposition protein TnsB YP_001185451.1 KEGG: ilo:IL2613 transposon Tn7 transposition protein TnsA YP_001185452.1 PFAM: protein of unknown function DUF1526; KEGG: cef:CE0419 hypothetical protein YP_001185455.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001185456.1 PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein; KEGG: son:SO4742 transcriptional regulator, DeoR family YP_001185457.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO4743 TonB-dependent receptor, putative YP_001185458.1 KEGG: she:Shewmr4_3923 UDP-N-acetylglucosamine pyrophosphorylase; TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase YP_001185459.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001185460.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001185461.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001185462.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001185463.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001185464.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001185465.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001185466.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001185467.1 PFAM: ATP synthase I chain; KEGG: shm:Shewmr7_4024 ATP synthase I chain YP_001185468.1 TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: shm:Shewmr7_4025 ParB-like partition proteins YP_001185469.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: shm:Shewmr7_4026 cobyrinic acid a,c-diamide synthase YP_001185470.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001185471.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001185472.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001185473.1 PFAM: TGF-beta receptor, type I/II extracellular region; KEGG: she:Shewmr4_3938 TGF-beta receptor, type I/II extracellular region YP_001185474.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: rso:RSp0313 probable multidrug efflux system protein YP_001185475.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rso:RS05454 probable two component response regulator transcription regulator protein YP_001185476.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: rru:Rru_A2930 periplasmic sensor signal transduction histidine kinase YP_001185477.1 KEGG: sdn:Sden_3021 integrase, catalytic region YP_001185481.1 PFAM: Resolvase, N-terminal domain; KEGG: atc:AGR_L_1981 hypothetical protein YP_001185482.1 KEGG: hch:HCH_05031 predicted transcriptional regulator YP_001185483.1 PFAM: N-6 DNA methylase; KEGG: vvy:VV2208 type I restriction-modification system methyltransferase subunit YP_001185484.1 KEGG: cch:Cag_1884 hypothetical protein YP_001185485.1 PFAM: AAA-4 family protein; KEGG: cch:Cag_1885 putative transcriptional regulator YP_001185486.1 PFAM: N-6 DNA methylase; KEGG: vvy:VV2206 type I restriction-modification system methyltransferase subunit YP_001185487.1 PFAM: restriction modification system DNA specificity domain; KEGG: vfi:VFA0538 type I restriction-modification system specificity subunit YP_001185488.1 KEGG: vvy:VV2204 putative type I site-specific restriction-modification system, R (restriction) subunit; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like YP_001185489.1 KEGG: aci:ACIAD0152 hypothetical protein YP_001185490.1 KEGG: eci:UTI89_C4212 putative cytoplasmic protein YP_001185492.1 KEGG: shm:Shewmr7_0346 superfamily II helicase and inactivated derivatives-like protein YP_001185493.1 TIGRFAM: DNA binding domain, excisionase family; PFAM: Prophage CP4-57 regulatory; KEGG: bfr:BF2790 putative excisionase YP_001185494.1 KEGG: sfr:Sfri_2519 hypothetical protein YP_001185495.1 KEGG: sfr:Sfri_2520 hypothetical protein YP_001185496.1 KEGG: sfr:Sfri_2521 hypothetical protein YP_001185497.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: tcx:Tcr_2095 heavy metal efflux pump CzcA YP_001185498.1 KEGG: tcx:Tcr_2096 secretion protein HlyD YP_001185499.1 KEGG: tcx:Tcr_2097 outer membrane efflux protein YP_001185500.1 PFAM: peptidase M48, Ste24p; peptidase M56, BlaR1; KEGG: sfr:Sfri_2522 peptidase M56, BlaR1 YP_001185501.1 PFAM: transcriptional regulator TrmB; Penicillinase repressor; KEGG: sfr:Sfri_2523 transcriptional repressor, CopY family protein YP_001185502.1 PFAM: phage integrase family protein; KEGG: pgi:PG0874 mobilizable transposon, int protein YP_001185503.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001185504.1 PFAM: 60 kDa inner membrane insertion protein; KEGG: shm:Shewmr7_4032 60 kDa inner membrane insertion protein YP_001185505.1 PFAM: protein of unknown function DUF37; KEGG: son:SO0005 conserved hypothetical protein TIGR00278 YP_001185506.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001185507.1 in Escherichia coli transcription of this gene is enhanced by polyamines