-- dump date   	20140620_064840
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
344609000001	Replication protein; Region: Rep_1; pfam01446
344609000002	DNA topoisomerase III; Provisional; Region: PRK07726
344609000003	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
344609000004	active site
344609000005	putative interdomain interaction site [polypeptide binding]; other site
344609000006	putative metal-binding site [ion binding]; other site
344609000007	putative nucleotide binding site [chemical binding]; other site
344609000008	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
344609000009	domain I; other site
344609000010	DNA binding groove [nucleotide binding]
344609000011	phosphate binding site [ion binding]; other site
344609000012	domain II; other site
344609000013	domain III; other site
344609000014	nucleotide binding site [chemical binding]; other site
344609000015	catalytic site [active]
344609000016	domain IV; other site
344609000017	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
344609000018	Haemolysin expression modulating protein; Region: HHA; pfam05321
344609000019	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
344609000020	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
344609000021	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
344609000022	active site
344609000023	catalytic residues [active]
344609000024	DNA binding site [nucleotide binding]
344609000025	Int/Topo IB signature motif; other site
344609000026	ParA-like protein; Provisional; Region: PHA02518
344609000027	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
344609000028	P-loop; other site
344609000029	Magnesium ion binding site [ion binding]; other site
344609000030	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
344609000031	Initiator Replication protein; Region: Rep_3; pfam01051
344609000032	putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683
344609000033	Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681
344609000034	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
344609000035	HSP70 interaction site [polypeptide binding]; other site
344609000036	putative zinc finger/helix-turn-helix protein, YgiT family; Region: CxxCG_CxxCG_HTH; TIGR03830
344609000037	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
344609000038	HicB family; Region: HicB; pfam05534
344609000039	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
344609000040	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
344609000041	N-acetyl-D-glucosamine binding site [chemical binding]; other site
344609000042	catalytic residue [active]
344609000043	TrbC/VIRB2 family; Region: TrbC; pfam04956
344609000044	Type IV secretory pathway, VirB3-like protein; Region: VirB3; cl01501
344609000045	type IV secretion/conjugal transfer ATPase, VirB4 family; Region: VirB4_CagE; TIGR00929
344609000046	CagE, TrbE, VirB family, component of type IV transporter system; Region: CagE_TrbE_VirB; pfam03135
344609000047	Type IV secretion system proteins; Region: T4SS; pfam07996
344609000048	TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; pfam04610
344609000049	VirB8 protein; Region: VirB8; pfam04335
344609000050	VirB9/CagX/TrbG, a component of the type IV secretion system; Region: VirB9_CagX_TrbG; cd06911
344609000051	VirB7 interaction site; other site
344609000052	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
344609000053	P-type DNA transfer ATPase VirB11; Region: VirB11; TIGR02788
344609000054	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
344609000055	Walker A motif; other site
344609000056	hexamer interface [polypeptide binding]; other site
344609000057	ATP binding site [chemical binding]; other site
344609000058	Walker B motif; other site
344609000059	type IV secretion system component VirD4; Provisional; Region: PRK13897
344609000060	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
344609000061	Walker A motif; other site
344609000062	ATP binding site [chemical binding]; other site
344609000063	Walker B motif; other site
344609000064	Cag pathogenicity island protein Cag12; Region: Cag12; pfam13117
344609000065	TrbM; Region: TrbM; pfam07424
344609000066	Staphylococcal nuclease homologues; Region: SNc; smart00318
344609000067	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cd00175
344609000068	Catalytic site; other site
344609000069	Acetyl-CoA carboxylase beta subunit [Lipid metabolism]; Region: AccD; COG0777
344609000070	Threonine operon leader
344609000071	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
344609000072	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
344609000073	putative catalytic residues [active]
344609000074	putative nucleotide binding site [chemical binding]; other site
344609000075	putative aspartate binding site [chemical binding]; other site
344609000076	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
344609000077	dimer interface [polypeptide binding]; other site
344609000078	putative threonine allosteric regulatory site; other site
344609000079	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
344609000080	putative threonine allosteric regulatory site; other site
344609000081	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
344609000082	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
344609000083	homoserine kinase; Region: thrB; TIGR00191
344609000084	Protein of unknown function; Region: YhfT; pfam10797
344609000085	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
344609000086	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
344609000087	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
344609000088	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609000089	catalytic residue [active]
344609000090	hypothetical protein; Validated; Region: PRK02101
344609000091	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
344609000092	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
344609000093	transaldolase-like protein; Provisional; Region: PTZ00411
344609000094	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
344609000095	active site
344609000096	dimer interface [polypeptide binding]; other site
344609000097	catalytic residue [active]
344609000098	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
344609000099	MPT binding site; other site
344609000100	trimer interface [polypeptide binding]; other site
344609000101	hypothetical protein; Provisional; Region: PRK10659
344609000102	hypothetical protein; Provisional; Region: PRK10236
344609000103	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
344609000104	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
344609000105	Protein of unknown function (DUF2541); Region: DUF2541; cl08090
344609000106	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609000107	HTH-like domain; Region: HTH_21; pfam13276
344609000108	Integrase core domain; Region: rve; pfam00665
344609000109	Integrase core domain; Region: rve_3; pfam13683
344609000110	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609000111	Protein of unknown function (DUF2541); Region: DUF2541; cl08090
344609000112	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
344609000113	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
344609000114	nucleotide binding site [chemical binding]; other site
344609000115	NEF interaction site [polypeptide binding]; other site
344609000116	SBD interface [polypeptide binding]; other site
344609000117	chaperone protein DnaJ; Provisional; Region: PRK10767
344609000118	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
344609000119	HSP70 interaction site [polypeptide binding]; other site
344609000120	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
344609000121	substrate binding site [polypeptide binding]; other site
344609000122	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
344609000123	Zn binding sites [ion binding]; other site
344609000124	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
344609000125	dimer interface [polypeptide binding]; other site
344609000126	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
344609000127	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
344609000128	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609000129	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
344609000130	putative dimerization interface [polypeptide binding]; other site
344609000131	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609000132	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609000133	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609000134	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609000135	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609000136	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609000137	Transposase; Region: HTH_Tnp_1; pfam01527
344609000138	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609000139	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609000140	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
344609000141	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
344609000142	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
344609000143	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
344609000144	active site
344609000145	Riboflavin kinase; Region: Flavokinase; smart00904
344609000146	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
344609000147	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
344609000148	HIGH motif; other site
344609000149	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
344609000150	active site
344609000151	KMSKS motif; other site
344609000152	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
344609000153	tRNA binding surface [nucleotide binding]; other site
344609000154	anticodon binding site; other site
344609000155	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
344609000156	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
344609000157	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
344609000158	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
344609000159	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
344609000160	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
344609000161	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
344609000162	active site
344609000163	tetramer interface [polypeptide binding]; other site
344609000164	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
344609000165	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
344609000166	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
344609000167	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
344609000168	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
344609000169	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
344609000170	catalytic site [active]
344609000171	subunit interface [polypeptide binding]; other site
344609000172	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
344609000173	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
344609000174	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
344609000175	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
344609000176	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
344609000177	ATP-grasp domain; Region: ATP-grasp_4; cl17255
344609000178	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
344609000179	IMP binding site; other site
344609000180	dimer interface [polypeptide binding]; other site
344609000181	interdomain contacts; other site
344609000182	partial ornithine binding site; other site
344609000183	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609000184	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
344609000185	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
344609000186	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
344609000187	TrkA-N domain; Region: TrkA_N; pfam02254
344609000188	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
344609000189	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
344609000190	folate binding site [chemical binding]; other site
344609000191	NADP+ binding site [chemical binding]; other site
344609000192	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
344609000193	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
344609000194	active site
344609000195	metal binding site [ion binding]; metal-binding site
344609000196	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
344609000197	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
344609000198	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
344609000199	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
344609000200	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
344609000201	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
344609000202	SurA N-terminal domain; Region: SurA_N; pfam09312
344609000203	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
344609000204	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
344609000205	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
344609000206	OstA-like protein; Region: OstA; pfam03968
344609000207	Organic solvent tolerance protein; Region: OstA_C; pfam04453
344609000208	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
344609000209	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
344609000210	putative metal binding site [ion binding]; other site
344609000211	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
344609000212	HSP70 interaction site [polypeptide binding]; other site
344609000213	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
344609000214	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
344609000215	active site
344609000216	ATP-dependent helicase HepA; Validated; Region: PRK04914
344609000217	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
344609000218	ATP binding site [chemical binding]; other site
344609000219	putative Mg++ binding site [ion binding]; other site
344609000220	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
344609000221	nucleotide binding region [chemical binding]; other site
344609000222	ATP-binding site [chemical binding]; other site
344609000223	DNA polymerase II; Reviewed; Region: PRK05762
344609000224	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
344609000225	active site
344609000226	catalytic site [active]
344609000227	substrate binding site [chemical binding]; other site
344609000228	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
344609000229	active site
344609000230	metal-binding site
344609000231	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
344609000232	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
344609000233	intersubunit interface [polypeptide binding]; other site
344609000234	active site
344609000235	Zn2+ binding site [ion binding]; other site
344609000236	L-arabinose isomerase; Provisional; Region: PRK02929
344609000237	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
344609000238	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
344609000239	trimer interface [polypeptide binding]; other site
344609000240	putative substrate binding site [chemical binding]; other site
344609000241	putative metal binding site [ion binding]; other site
344609000242	ribulokinase; Provisional; Region: PRK04123
344609000243	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
344609000244	N- and C-terminal domain interface [polypeptide binding]; other site
344609000245	active site
344609000246	MgATP binding site [chemical binding]; other site
344609000247	catalytic site [active]
344609000248	metal binding site [ion binding]; metal-binding site
344609000249	carbohydrate binding site [chemical binding]; other site
344609000250	homodimer interface [polypeptide binding]; other site
344609000251	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
344609000252	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
344609000253	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609000254	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609000255	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
344609000256	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
344609000257	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
344609000258	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
344609000259	Walker A/P-loop; other site
344609000260	ATP binding site [chemical binding]; other site
344609000261	Q-loop/lid; other site
344609000262	ABC transporter signature motif; other site
344609000263	Walker B; other site
344609000264	D-loop; other site
344609000265	H-loop/switch region; other site
344609000266	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
344609000267	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609000268	dimer interface [polypeptide binding]; other site
344609000269	conserved gate region; other site
344609000270	putative PBP binding loops; other site
344609000271	ABC-ATPase subunit interface; other site
344609000272	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609000273	dimer interface [polypeptide binding]; other site
344609000274	conserved gate region; other site
344609000275	putative PBP binding loops; other site
344609000276	ABC-ATPase subunit interface; other site
344609000277	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
344609000278	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
344609000279	transcriptional regulator SgrR; Provisional; Region: PRK13626
344609000280	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
344609000281	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
344609000282	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609000283	sugar efflux transporter; Region: 2A0120; TIGR00899
344609000284	putative substrate translocation pore; other site
344609000285	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
344609000286	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
344609000287	substrate binding site [chemical binding]; other site
344609000288	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
344609000289	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
344609000290	substrate binding site [chemical binding]; other site
344609000291	ligand binding site [chemical binding]; other site
344609000292	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
344609000293	tartrate dehydrogenase; Region: TTC; TIGR02089
344609000294	2-isopropylmalate synthase; Validated; Region: PRK00915
344609000295	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
344609000296	active site
344609000297	catalytic residues [active]
344609000298	metal binding site [ion binding]; metal-binding site
344609000299	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
344609000300	Leucine operon leader
344609000301	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
344609000302	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609000303	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
344609000304	putative substrate binding pocket [chemical binding]; other site
344609000305	putative dimerization interface [polypeptide binding]; other site
344609000306	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
344609000307	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
344609000308	putative valine binding site [chemical binding]; other site
344609000309	dimer interface [polypeptide binding]; other site
344609000310	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
344609000311	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
344609000312	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
344609000313	DNA binding site [nucleotide binding]
344609000314	domain linker motif; other site
344609000315	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
344609000316	dimerization interface [polypeptide binding]; other site
344609000317	ligand binding site [chemical binding]; other site
344609000318	mraZ protein; Region: TIGR00242
344609000319	MraZ protein; Region: MraZ; pfam02381
344609000320	MraZ protein; Region: MraZ; pfam02381
344609000321	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
344609000322	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
344609000323	cell division protein FtsL; Provisional; Region: PRK10772
344609000324	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
344609000325	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
344609000326	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
344609000327	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
344609000328	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
344609000329	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
344609000330	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
344609000331	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
344609000332	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
344609000333	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
344609000334	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
344609000335	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
344609000336	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
344609000337	Mg++ binding site [ion binding]; other site
344609000338	putative catalytic motif [active]
344609000339	putative substrate binding site [chemical binding]; other site
344609000340	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
344609000341	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
344609000342	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
344609000343	cell division protein FtsW; Provisional; Region: PRK10774
344609000344	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
344609000345	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
344609000346	active site
344609000347	homodimer interface [polypeptide binding]; other site
344609000348	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
344609000349	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
344609000350	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
344609000351	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
344609000352	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
344609000353	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
344609000354	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
344609000355	cell division protein FtsQ; Provisional; Region: PRK10775
344609000356	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
344609000357	Cell division protein FtsQ; Region: FtsQ; pfam03799
344609000358	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
344609000359	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
344609000360	Cell division protein FtsA; Region: FtsA; pfam14450
344609000361	cell division protein FtsZ; Validated; Region: PRK09330
344609000362	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
344609000363	nucleotide binding site [chemical binding]; other site
344609000364	SulA interaction site; other site
344609000365	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
344609000366	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
344609000367	SecA regulator SecM; Provisional; Region: PRK02943
344609000368	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
344609000369	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
344609000370	SEC-C motif; Region: SEC-C; pfam02810
344609000371	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
344609000372	active site
344609000373	8-oxo-dGMP binding site [chemical binding]; other site
344609000374	nudix motif; other site
344609000375	metal binding site [ion binding]; metal-binding site
344609000376	DNA gyrase inhibitor; Reviewed; Region: PRK00418
344609000377	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
344609000378	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
344609000379	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
344609000380	CoA-binding site [chemical binding]; other site
344609000381	ATP-binding [chemical binding]; other site
344609000382	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
344609000383	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
344609000384	active site
344609000385	type IV pilin biogenesis protein; Provisional; Region: PRK10573
344609000386	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
344609000387	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
344609000388	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609000389	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
344609000390	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
344609000391	dimerization interface [polypeptide binding]; other site
344609000392	active site
344609000393	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
344609000394	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
344609000395	amidase catalytic site [active]
344609000396	Zn binding residues [ion binding]; other site
344609000397	substrate binding site [chemical binding]; other site
344609000398	regulatory protein AmpE; Provisional; Region: PRK10987
344609000399	aromatic amino acid transporter; Provisional; Region: PRK10238
344609000400	Transcriptional regulators [Transcription]; Region: FadR; COG2186
344609000401	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
344609000402	DNA-binding site [nucleotide binding]; DNA binding site
344609000403	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
344609000404	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
344609000405	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
344609000406	dimer interface [polypeptide binding]; other site
344609000407	TPP-binding site [chemical binding]; other site
344609000408	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
344609000409	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
344609000410	E3 interaction surface; other site
344609000411	lipoyl attachment site [posttranslational modification]; other site
344609000412	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
344609000413	E3 interaction surface; other site
344609000414	lipoyl attachment site [posttranslational modification]; other site
344609000415	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
344609000416	E3 interaction surface; other site
344609000417	lipoyl attachment site [posttranslational modification]; other site
344609000418	e3 binding domain; Region: E3_binding; pfam02817
344609000419	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
344609000420	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
344609000421	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
344609000422	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
344609000423	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
344609000424	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
344609000425	Protein of unknown function (DUF3106); Region: DUF3106; pfam11304
344609000426	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
344609000427	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
344609000428	substrate binding site [chemical binding]; other site
344609000429	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
344609000430	substrate binding site [chemical binding]; other site
344609000431	ligand binding site [chemical binding]; other site
344609000432	hypothetical protein; Provisional; Region: PRK05248
344609000433	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
344609000434	spermidine synthase; Provisional; Region: PRK00811
344609000435	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609000436	S-adenosylmethionine binding site [chemical binding]; other site
344609000437	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
344609000438	multicopper oxidase; Provisional; Region: PRK10965
344609000439	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
344609000440	Multicopper oxidase; Region: Cu-oxidase; pfam00394
344609000441	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
344609000442	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
344609000443	active site
344609000444	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
344609000445	active site clefts [active]
344609000446	zinc binding site [ion binding]; other site
344609000447	dimer interface [polypeptide binding]; other site
344609000448	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
344609000449	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
344609000450	Walker A/P-loop; other site
344609000451	ATP binding site [chemical binding]; other site
344609000452	Q-loop/lid; other site
344609000453	ABC transporter signature motif; other site
344609000454	Walker B; other site
344609000455	D-loop; other site
344609000456	H-loop/switch region; other site
344609000457	inner membrane transport permease; Provisional; Region: PRK15066
344609000458	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
344609000459	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
344609000460	active pocket/dimerization site; other site
344609000461	active site
344609000462	phosphorylation site [posttranslational modification]
344609000463	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
344609000464	tetramerization interface [polypeptide binding]; other site
344609000465	active site
344609000466	Uncharacterized conserved protein [Function unknown]; Region: COG5464
344609000467	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
344609000468	pantoate--beta-alanine ligase; Region: panC; TIGR00018
344609000469	Pantoate-beta-alanine ligase; Region: PanC; cd00560
344609000470	active site
344609000471	ATP-binding site [chemical binding]; other site
344609000472	pantoate-binding site; other site
344609000473	HXXH motif; other site
344609000474	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
344609000475	oligomerization interface [polypeptide binding]; other site
344609000476	active site
344609000477	metal binding site [ion binding]; metal-binding site
344609000478	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609000479	Transposase; Region: HTH_Tnp_1; pfam01527
344609000480	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609000481	Fimbrial protein; Region: Fimbrial; cl01416
344609000482	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
344609000483	catalytic center binding site [active]
344609000484	ATP binding site [chemical binding]; other site
344609000485	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
344609000486	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
344609000487	active site
344609000488	NTP binding site [chemical binding]; other site
344609000489	metal binding triad [ion binding]; metal-binding site
344609000490	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
344609000491	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
344609000492	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
344609000493	tRNA synthetases class I (E and Q), catalytic domain; Region: tRNA-synt_1c; pfam00749
344609000494	active site
344609000495	nucleotide binding site [chemical binding]; other site
344609000496	HIGH motif; other site
344609000497	KMSKS motif; other site
344609000498	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
344609000499	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
344609000500	2'-5' RNA ligase; Provisional; Region: PRK15124
344609000501	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
344609000502	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
344609000503	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
344609000504	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
344609000505	ATP binding site [chemical binding]; other site
344609000506	putative Mg++ binding site [ion binding]; other site
344609000507	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
344609000508	nucleotide binding region [chemical binding]; other site
344609000509	ATP-binding site [chemical binding]; other site
344609000510	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
344609000511	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
344609000512	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
344609000513	Transglycosylase; Region: Transgly; pfam00912
344609000514	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
344609000515	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
344609000516	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
344609000517	N-terminal plug; other site
344609000518	ligand-binding site [chemical binding]; other site
344609000519	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
344609000520	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
344609000521	Walker A/P-loop; other site
344609000522	ATP binding site [chemical binding]; other site
344609000523	Q-loop/lid; other site
344609000524	ABC transporter signature motif; other site
344609000525	Walker B; other site
344609000526	D-loop; other site
344609000527	H-loop/switch region; other site
344609000528	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
344609000529	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
344609000530	siderophore binding site; other site
344609000531	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
344609000532	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
344609000533	ABC-ATPase subunit  interface; other site
344609000534	dimer interface [polypeptide binding]; other site
344609000535	putative PBP binding regions; other site
344609000536	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
344609000537	ABC-ATPase subunit  interface; other site
344609000538	dimer interface [polypeptide binding]; other site
344609000539	putative PBP binding regions; other site
344609000540	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
344609000541	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
344609000542	inhibitor-cofactor binding pocket; inhibition site
344609000543	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609000544	catalytic residue [active]
344609000545	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
344609000546	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
344609000547	Cl- selectivity filter; other site
344609000548	Cl- binding residues [ion binding]; other site
344609000549	pore gating glutamate residue; other site
344609000550	dimer interface [polypeptide binding]; other site
344609000551	H+/Cl- coupling transport residue; other site
344609000552	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
344609000553	hypothetical protein; Provisional; Region: PRK10578
344609000554	UPF0126 domain; Region: UPF0126; pfam03458
344609000555	UPF0126 domain; Region: UPF0126; pfam03458
344609000556	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
344609000557	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
344609000558	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
344609000559	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
344609000560	Zn2+ binding site [ion binding]; other site
344609000561	Mg2+ binding site [ion binding]; other site
344609000562	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
344609000563	serine endoprotease; Provisional; Region: PRK10942
344609000564	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
344609000565	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
344609000566	protein binding site [polypeptide binding]; other site
344609000567	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
344609000568	hypothetical protein; Provisional; Region: PRK13677
344609000569	phosphodiesterase YaeI; Provisional; Region: PRK11340
344609000570	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
344609000571	putative active site [active]
344609000572	putative metal binding site [ion binding]; other site
344609000573	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
344609000574	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
344609000575	trimer interface [polypeptide binding]; other site
344609000576	active site
344609000577	substrate binding site [chemical binding]; other site
344609000578	CoA binding site [chemical binding]; other site
344609000579	PII uridylyl-transferase; Provisional; Region: PRK05007
344609000580	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
344609000581	metal binding triad; other site
344609000582	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
344609000583	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
344609000584	Zn2+ binding site [ion binding]; other site
344609000585	Mg2+ binding site [ion binding]; other site
344609000586	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
344609000587	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
344609000588	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
344609000589	active site
344609000590	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
344609000591	rRNA interaction site [nucleotide binding]; other site
344609000592	S8 interaction site; other site
344609000593	putative laminin-1 binding site; other site
344609000594	elongation factor Ts; Provisional; Region: tsf; PRK09377
344609000595	UBA/TS-N domain; Region: UBA; pfam00627
344609000596	Elongation factor TS; Region: EF_TS; pfam00889
344609000597	Elongation factor TS; Region: EF_TS; pfam00889
344609000598	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
344609000599	putative nucleotide binding site [chemical binding]; other site
344609000600	uridine monophosphate binding site [chemical binding]; other site
344609000601	homohexameric interface [polypeptide binding]; other site
344609000602	ribosome recycling factor; Reviewed; Region: frr; PRK00083
344609000603	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
344609000604	hinge region; other site
344609000605	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
344609000606	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
344609000607	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
344609000608	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
344609000609	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
344609000610	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
344609000611	catalytic residue [active]
344609000612	putative FPP diphosphate  binding site; other site
344609000613	putative FPP binding hydrophobic cleft; other site
344609000614	dimer interface [polypeptide binding]; other site
344609000615	putative IPP diphosphate binding site; other site
344609000616	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
344609000617	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
344609000618	zinc metallopeptidase RseP; Provisional; Region: PRK10779
344609000619	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
344609000620	active site
344609000621	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
344609000622	protein binding site [polypeptide binding]; other site
344609000623	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
344609000624	putative substrate binding region [chemical binding]; other site
344609000625	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
344609000626	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
344609000627	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
344609000628	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
344609000629	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
344609000630	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
344609000631	Surface antigen; Region: Bac_surface_Ag; pfam01103
344609000632	periplasmic chaperone; Provisional; Region: PRK10780
344609000633	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
344609000634	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
344609000635	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
344609000636	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
344609000637	trimer interface [polypeptide binding]; other site
344609000638	active site
344609000639	UDP-GlcNAc binding site [chemical binding]; other site
344609000640	lipid binding site [chemical binding]; lipid-binding site
344609000641	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
344609000642	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
344609000643	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
344609000644	active site
344609000645	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
344609000646	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
344609000647	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
344609000648	RNA/DNA hybrid binding site [nucleotide binding]; other site
344609000649	active site
344609000650	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
344609000651	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
344609000652	putative active site [active]
344609000653	putative PHP Thumb interface [polypeptide binding]; other site
344609000654	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
344609000655	generic binding surface II; other site
344609000656	generic binding surface I; other site
344609000657	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
344609000658	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
344609000659	lysine decarboxylase LdcC; Provisional; Region: PRK15399
344609000660	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
344609000661	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
344609000662	homodimer interface [polypeptide binding]; other site
344609000663	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609000664	catalytic residue [active]
344609000665	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
344609000666	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
344609000667	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
344609000668	putative metal binding site [ion binding]; other site
344609000669	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
344609000670	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
344609000671	Ligand Binding Site [chemical binding]; other site
344609000672	TilS substrate binding domain; Region: TilS; pfam09179
344609000673	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
344609000674	Rho-binding antiterminator; Provisional; Region: PRK11625
344609000675	hypothetical protein; Provisional; Region: PRK04964
344609000676	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
344609000677	hypothetical protein; Provisional; Region: PRK09256
344609000678	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
344609000679	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
344609000680	NlpE N-terminal domain; Region: NlpE; pfam04170
344609000681	hypothetical protein; Provisional; Region: PRK11479
344609000682	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
344609000683	prolyl-tRNA synthetase; Provisional; Region: PRK09194
344609000684	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
344609000685	dimer interface [polypeptide binding]; other site
344609000686	motif 1; other site
344609000687	active site
344609000688	motif 2; other site
344609000689	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
344609000690	putative deacylase active site [active]
344609000691	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
344609000692	active site
344609000693	motif 3; other site
344609000694	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
344609000695	anticodon binding site; other site
344609000696	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
344609000697	homodimer interaction site [polypeptide binding]; other site
344609000698	cofactor binding site; other site
344609000699	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
344609000700	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
344609000701	lipoprotein, YaeC family; Region: TIGR00363
344609000702	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609000703	dimer interface [polypeptide binding]; other site
344609000704	conserved gate region; other site
344609000705	ABC-ATPase subunit interface; other site
344609000706	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
344609000707	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
344609000708	Walker A/P-loop; other site
344609000709	ATP binding site [chemical binding]; other site
344609000710	Q-loop/lid; other site
344609000711	ABC transporter signature motif; other site
344609000712	Walker B; other site
344609000713	D-loop; other site
344609000714	H-loop/switch region; other site
344609000715	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
344609000716	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
344609000717	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609000718	active site
344609000719	motif I; other site
344609000720	motif II; other site
344609000721	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
344609000722	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
344609000723	active site
344609000724	catalytic tetrad [active]
344609000725	Transcriptional regulator [Transcription]; Region: LysR; COG0583
344609000726	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609000727	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
344609000728	putative effector binding pocket; other site
344609000729	dimerization interface [polypeptide binding]; other site
344609000730	hypothetical protein; Provisional; Region: PRK05421
344609000731	putative catalytic site [active]
344609000732	putative metal binding site [ion binding]; other site
344609000733	putative phosphate binding site [ion binding]; other site
344609000734	putative catalytic site [active]
344609000735	putative phosphate binding site [ion binding]; other site
344609000736	putative metal binding site [ion binding]; other site
344609000737	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609000738	S-adenosylmethionine binding site [chemical binding]; other site
344609000739	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
344609000740	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
344609000741	N-acetyl-D-glucosamine binding site [chemical binding]; other site
344609000742	catalytic residue [active]
344609000743	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
344609000744	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
344609000745	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
344609000746	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609000747	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
344609000748	RNA/DNA hybrid binding site [nucleotide binding]; other site
344609000749	active site
344609000750	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
344609000751	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
344609000752	active site
344609000753	catalytic site [active]
344609000754	substrate binding site [chemical binding]; other site
344609000755	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609000756	C-N hydrolase family amidase; Provisional; Region: PRK10438
344609000757	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
344609000758	putative active site [active]
344609000759	catalytic triad [active]
344609000760	dimer interface [polypeptide binding]; other site
344609000761	multimer interface [polypeptide binding]; other site
344609000762	C-lysozyme inhibitor; Provisional; Region: PRK09993
344609000763	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
344609000764	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
344609000765	active site
344609000766	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
344609000767	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
344609000768	dimer interface [polypeptide binding]; other site
344609000769	active site
344609000770	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
344609000771	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
344609000772	putative active site [active]
344609000773	putative dimer interface [polypeptide binding]; other site
344609000774	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
344609000775	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
344609000776	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609000777	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
344609000778	NlpC/P60 family; Region: NLPC_P60; pfam00877
344609000779	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609000780	Transposase; Region: HTH_Tnp_1; pfam01527
344609000781	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
344609000782	active site
344609000783	DNA polymerase IV; Validated; Region: PRK02406
344609000784	DNA binding site [nucleotide binding]
344609000785	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
344609000786	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
344609000787	Coenzyme A binding pocket [chemical binding]; other site
344609000788	Uncharacterized protein family UPF0027; Region: UPF0027; cl17455
344609000789	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609000790	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609000791	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
344609000792	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
344609000793	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
344609000794	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
344609000795	metal binding site [ion binding]; metal-binding site
344609000796	dimer interface [polypeptide binding]; other site
344609000797	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
344609000798	active site
344609000799	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
344609000800	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
344609000801	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
344609000802	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
344609000803	trimer interface [polypeptide binding]; other site
344609000804	eyelet of channel; other site
344609000805	gamma-glutamyl kinase; Provisional; Region: PRK05429
344609000806	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
344609000807	nucleotide binding site [chemical binding]; other site
344609000808	homotetrameric interface [polypeptide binding]; other site
344609000809	putative phosphate binding site [ion binding]; other site
344609000810	putative allosteric binding site; other site
344609000811	PUA domain; Region: PUA; pfam01472
344609000812	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
344609000813	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
344609000814	putative catalytic cysteine [active]
344609000815	putative transposase OrfB; Reviewed; Region: PHA02517
344609000816	Integrase core domain; Region: rve; pfam00665
344609000817	Integrase core domain; Region: rve_3; pfam13683
344609000818	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609000819	Transposase; Region: HTH_Tnp_1; pfam01527
344609000820	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
344609000821	DNA-binding site [nucleotide binding]; DNA binding site
344609000822	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609000823	HTH-like domain; Region: HTH_21; pfam13276
344609000824	Integrase core domain; Region: rve; pfam00665
344609000825	Integrase core domain; Region: rve_3; pfam13683
344609000826	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
344609000827	catalytic residue [active]
344609000828	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609000829	Transposase; Region: HTH_Tnp_1; pfam01527
344609000830	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609000831	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609000832	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609000833	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609000834	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609000835	Uncharacterized conserved protein [Function unknown]; Region: COG1556
344609000836	iron-sulfur cluster-binding protein; Region: TIGR00273
344609000837	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
344609000838	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
344609000839	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
344609000840	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
344609000841	Cysteine-rich domain; Region: CCG; pfam02754
344609000842	Cysteine-rich domain; Region: CCG; pfam02754
344609000843	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609000844	putative transposase OrfB; Reviewed; Region: PHA02517
344609000845	Integrase core domain; Region: rve; pfam00665
344609000846	Integrase core domain; Region: rve_3; pfam13683
344609000847	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609000848	Transposase; Region: HTH_Tnp_1; pfam01527
344609000849	Protein of unknown function, DUF417; Region: DUF417; cl01162
344609000850	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
344609000851	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
344609000852	active site
344609000853	catalytic tetrad [active]
344609000854	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
344609000855	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609000856	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609000857	S-formylglutathione hydrolase; Region: PLN02442
344609000858	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
344609000859	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
344609000860	substrate binding site [chemical binding]; other site
344609000861	catalytic Zn binding site [ion binding]; other site
344609000862	NAD binding site [chemical binding]; other site
344609000863	structural Zn binding site [ion binding]; other site
344609000864	dimer interface [polypeptide binding]; other site
344609000865	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
344609000866	putative metal binding site [ion binding]; other site
344609000867	putative homodimer interface [polypeptide binding]; other site
344609000868	putative homotetramer interface [polypeptide binding]; other site
344609000869	putative homodimer-homodimer interface [polypeptide binding]; other site
344609000870	putative allosteric switch controlling residues; other site
344609000871	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609000872	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609000873	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609000874	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
344609000875	putative trimer interface [polypeptide binding]; other site
344609000876	putative CoA binding site [chemical binding]; other site
344609000877	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
344609000878	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
344609000879	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
344609000880	substrate binding pocket [chemical binding]; other site
344609000881	membrane-bound complex binding site; other site
344609000882	hinge residues; other site
344609000883	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
344609000884	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
344609000885	Walker A/P-loop; other site
344609000886	ATP binding site [chemical binding]; other site
344609000887	Q-loop/lid; other site
344609000888	ABC transporter signature motif; other site
344609000889	Walker B; other site
344609000890	D-loop; other site
344609000891	H-loop/switch region; other site
344609000892	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
344609000893	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609000894	dimer interface [polypeptide binding]; other site
344609000895	conserved gate region; other site
344609000896	putative PBP binding loops; other site
344609000897	ABC-ATPase subunit interface; other site
344609000898	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609000899	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184
344609000900	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
344609000901	dimer interface [polypeptide binding]; other site
344609000902	active site
344609000903	Schiff base residues; other site
344609000904	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609000905	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609000906	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; cl04114
344609000907	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609000908	HTH-like domain; Region: HTH_21; pfam13276
344609000909	Integrase core domain; Region: rve; pfam00665
344609000910	Integrase core domain; Region: rve_3; pfam13683
344609000911	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
344609000912	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
344609000913	Autotransporter beta-domain; Region: Autotransporter; pfam03797
344609000914	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
344609000915	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
344609000916	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
344609000917	microcin B17 transporter; Reviewed; Region: PRK11098
344609000918	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
344609000919	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
344609000920	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
344609000921	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
344609000922	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
344609000923	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
344609000924	anti-RssB factor; Provisional; Region: PRK10244
344609000925	hypothetical protein; Provisional; Region: PRK11505
344609000926	psiF repeat; Region: PsiF_repeat; pfam07769
344609000927	psiF repeat; Region: PsiF_repeat; pfam07769
344609000928	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
344609000929	MASE2 domain; Region: MASE2; pfam05230
344609000930	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
344609000931	metal binding site [ion binding]; metal-binding site
344609000932	active site
344609000933	I-site; other site
344609000934	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
344609000935	pyrroline-5-carboxylate reductase; Region: PLN02688
344609000936	hypothetical protein; Validated; Region: PRK00124
344609000937	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
344609000938	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
344609000939	ADP binding site [chemical binding]; other site
344609000940	magnesium binding site [ion binding]; other site
344609000941	putative shikimate binding site; other site
344609000942	hypothetical protein; Provisional; Region: PRK10380
344609000943	hypothetical protein; Provisional; Region: PRK10481
344609000944	hypothetical protein; Provisional; Region: PRK10579
344609000945	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
344609000946	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
344609000947	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
344609000948	fructokinase; Reviewed; Region: PRK09557
344609000949	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
344609000950	nucleotide binding site [chemical binding]; other site
344609000951	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609000952	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609000953	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
344609000954	MFS transport protein AraJ; Provisional; Region: PRK10091
344609000955	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609000956	putative substrate translocation pore; other site
344609000957	exonuclease subunit SbcC; Provisional; Region: PRK10246
344609000958	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609000959	Walker A/P-loop; other site
344609000960	ATP binding site [chemical binding]; other site
344609000961	Q-loop/lid; other site
344609000962	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609000963	ABC transporter signature motif; other site
344609000964	Walker B; other site
344609000965	D-loop; other site
344609000966	H-loop/switch region; other site
344609000967	exonuclease subunit SbcD; Provisional; Region: PRK10966
344609000968	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
344609000969	active site
344609000970	metal binding site [ion binding]; metal-binding site
344609000971	DNA binding site [nucleotide binding]
344609000972	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
344609000973	transcriptional regulator PhoB; Provisional; Region: PRK10161
344609000974	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609000975	active site
344609000976	phosphorylation site [posttranslational modification]
344609000977	intermolecular recognition site; other site
344609000978	dimerization interface [polypeptide binding]; other site
344609000979	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
344609000980	DNA binding site [nucleotide binding]
344609000981	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
344609000982	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
344609000983	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
344609000984	putative active site [active]
344609000985	heme pocket [chemical binding]; other site
344609000986	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609000987	dimer interface [polypeptide binding]; other site
344609000988	phosphorylation site [posttranslational modification]
344609000989	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609000990	ATP binding site [chemical binding]; other site
344609000991	Mg2+ binding site [ion binding]; other site
344609000992	G-X-G motif; other site
344609000993	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
344609000994	putative proline-specific permease; Provisional; Region: proY; PRK10580
344609000995	Spore germination protein; Region: Spore_permease; cl17796
344609000996	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
344609000997	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
344609000998	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
344609000999	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
344609001000	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
344609001001	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
344609001002	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
344609001003	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
344609001004	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
344609001005	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
344609001006	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
344609001007	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
344609001008	Protein export membrane protein; Region: SecD_SecF; pfam02355
344609001009	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
344609001010	active site
344609001011	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001012	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
344609001013	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
344609001014	hypothetical protein; Provisional; Region: PRK11530
344609001015	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
344609001016	ATP cone domain; Region: ATP-cone; pfam03477
344609001017	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
344609001018	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
344609001019	catalytic motif [active]
344609001020	Zn binding site [ion binding]; other site
344609001021	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
344609001022	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
344609001023	homopentamer interface [polypeptide binding]; other site
344609001024	active site
344609001025	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
344609001026	putative RNA binding site [nucleotide binding]; other site
344609001027	thiamine monophosphate kinase; Provisional; Region: PRK05731
344609001028	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
344609001029	ATP binding site [chemical binding]; other site
344609001030	dimerization interface [polypeptide binding]; other site
344609001031	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
344609001032	tetramer interfaces [polypeptide binding]; other site
344609001033	binuclear metal-binding site [ion binding]; other site
344609001034	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
344609001035	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
344609001036	active site
344609001037	catalytic tetrad [active]
344609001038	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
344609001039	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
344609001040	TPP-binding site; other site
344609001041	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
344609001042	PYR/PP interface [polypeptide binding]; other site
344609001043	dimer interface [polypeptide binding]; other site
344609001044	TPP binding site [chemical binding]; other site
344609001045	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
344609001046	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
344609001047	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
344609001048	substrate binding pocket [chemical binding]; other site
344609001049	chain length determination region; other site
344609001050	substrate-Mg2+ binding site; other site
344609001051	catalytic residues [active]
344609001052	aspartate-rich region 1; other site
344609001053	active site lid residues [active]
344609001054	aspartate-rich region 2; other site
344609001055	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
344609001056	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
344609001057	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
344609001058	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
344609001059	Ligand Binding Site [chemical binding]; other site
344609001060	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
344609001061	active site residue [active]
344609001062	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
344609001063	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
344609001064	conserved cys residue [active]
344609001065	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
344609001066	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
344609001067	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
344609001068	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
344609001069	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
344609001070	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609001071	Major Facilitator Superfamily; Region: MFS_1; pfam07690
344609001072	putative substrate translocation pore; other site
344609001073	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
344609001074	UbiA prenyltransferase family; Region: UbiA; pfam01040
344609001075	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
344609001076	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
344609001077	Subunit I/III interface [polypeptide binding]; other site
344609001078	Subunit III/IV interface [polypeptide binding]; other site
344609001079	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
344609001080	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
344609001081	D-pathway; other site
344609001082	Putative ubiquinol binding site [chemical binding]; other site
344609001083	Low-spin heme (heme b) binding site [chemical binding]; other site
344609001084	Putative water exit pathway; other site
344609001085	Binuclear center (heme o3/CuB) [ion binding]; other site
344609001086	K-pathway; other site
344609001087	Putative proton exit pathway; other site
344609001088	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
344609001089	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
344609001090	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
344609001091	muropeptide transporter; Reviewed; Region: ampG; PRK11902
344609001092	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609001093	putative substrate translocation pore; other site
344609001094	hypothetical protein; Provisional; Region: PRK11627
344609001095	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
344609001096	transcriptional regulator BolA; Provisional; Region: PRK11628
344609001097	trigger factor; Provisional; Region: tig; PRK01490
344609001098	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
344609001099	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
344609001100	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
344609001101	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
344609001102	oligomer interface [polypeptide binding]; other site
344609001103	active site residues [active]
344609001104	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
344609001105	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
344609001106	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609001107	Walker A motif; other site
344609001108	ATP binding site [chemical binding]; other site
344609001109	Walker B motif; other site
344609001110	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
344609001111	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
344609001112	Found in ATP-dependent protease La (LON); Region: LON; smart00464
344609001113	Found in ATP-dependent protease La (LON); Region: LON; smart00464
344609001114	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609001115	Walker A motif; other site
344609001116	ATP binding site [chemical binding]; other site
344609001117	Walker B motif; other site
344609001118	arginine finger; other site
344609001119	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
344609001120	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
344609001121	IHF dimer interface [polypeptide binding]; other site
344609001122	IHF - DNA interface [nucleotide binding]; other site
344609001123	periplasmic folding chaperone; Provisional; Region: PRK10788
344609001124	SurA N-terminal domain; Region: SurA_N_3; cl07813
344609001125	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
344609001126	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
344609001127	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
344609001128	active site
344609001129	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
344609001130	Ligand Binding Site [chemical binding]; other site
344609001131	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
344609001132	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
344609001133	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
344609001134	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
344609001135	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609001136	active site
344609001137	motif I; other site
344609001138	motif II; other site
344609001139	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
344609001140	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
344609001141	putative DNA binding site [nucleotide binding]; other site
344609001142	putative Zn2+ binding site [ion binding]; other site
344609001143	AsnC family; Region: AsnC_trans_reg; pfam01037
344609001144	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
344609001145	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
344609001146	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609001147	Walker A/P-loop; other site
344609001148	ATP binding site [chemical binding]; other site
344609001149	Q-loop/lid; other site
344609001150	ABC transporter signature motif; other site
344609001151	Walker B; other site
344609001152	D-loop; other site
344609001153	H-loop/switch region; other site
344609001154	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609001155	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
344609001156	Nitrogen regulatory protein P-II; Region: P-II; smart00938
344609001157	ammonium transporter; Provisional; Region: PRK10666
344609001158	acyl-CoA thioesterase II; Provisional; Region: PRK10526
344609001159	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
344609001160	active site
344609001161	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
344609001162	catalytic triad [active]
344609001163	dimer interface [polypeptide binding]; other site
344609001164	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
344609001165	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
344609001166	DNA binding site [nucleotide binding]
344609001167	active site
344609001168	Uncharacterized conserved protein [Function unknown]; Region: COG5507
344609001169	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
344609001170	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
344609001171	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
344609001172	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
344609001173	maltose O-acetyltransferase; Provisional; Region: PRK10092
344609001174	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
344609001175	active site
344609001176	substrate binding site [chemical binding]; other site
344609001177	trimer interface [polypeptide binding]; other site
344609001178	CoA binding site [chemical binding]; other site
344609001179	gene expression modulator; Provisional; Region: PRK10945
344609001180	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
344609001181	Protein export membrane protein; Region: SecD_SecF; cl14618
344609001182	Protein export membrane protein; Region: SecD_SecF; cl14618
344609001183	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
344609001184	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
344609001185	HlyD family secretion protein; Region: HlyD_3; pfam13437
344609001186	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
344609001187	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
344609001188	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
344609001189	hypothetical protein; Provisional; Region: PRK11281
344609001190	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
344609001191	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
344609001192	Mechanosensitive ion channel; Region: MS_channel; pfam00924
344609001193	hypothetical protein; Provisional; Region: PRK11038
344609001194	primosomal replication protein N''; Provisional; Region: PRK10093
344609001195	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
344609001196	active site
344609001197	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
344609001198	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609001199	Walker A motif; other site
344609001200	ATP binding site [chemical binding]; other site
344609001201	Walker B motif; other site
344609001202	DNA polymerase III subunit delta'; Validated; Region: PRK08485
344609001203	arginine finger; other site
344609001204	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
344609001205	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
344609001206	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
344609001207	DnaX ribosomal frameshifting element
344609001208	hypothetical protein; Validated; Region: PRK00153
344609001209	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
344609001210	RecR protein; Region: RecR; pfam02132
344609001211	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
344609001212	putative active site [active]
344609001213	putative metal-binding site [ion binding]; other site
344609001214	tetramer interface [polypeptide binding]; other site
344609001215	heat shock protein 90; Provisional; Region: PRK05218
344609001216	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609001217	ATP binding site [chemical binding]; other site
344609001218	Mg2+ binding site [ion binding]; other site
344609001219	G-X-G motif; other site
344609001220	adenylate kinase; Reviewed; Region: adk; PRK00279
344609001221	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
344609001222	AMP-binding site [chemical binding]; other site
344609001223	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
344609001224	ferrochelatase; Region: hemH; TIGR00109
344609001225	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
344609001226	C-terminal domain interface [polypeptide binding]; other site
344609001227	active site
344609001228	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
344609001229	active site
344609001230	N-terminal domain interface [polypeptide binding]; other site
344609001231	acetyl esterase; Provisional; Region: PRK10162
344609001232	inosine/guanosine kinase; Provisional; Region: PRK15074
344609001233	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
344609001234	putative cation:proton antiport protein; Provisional; Region: PRK10669
344609001235	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
344609001236	TrkA-N domain; Region: TrkA_N; pfam02254
344609001237	polyol permease family; Region: 2A0118; TIGR00897
344609001238	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001239	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609001240	Major Facilitator Superfamily; Region: MFS_1; pfam07690
344609001241	putative substrate translocation pore; other site
344609001242	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
344609001243	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
344609001244	active site
344609001245	metal binding site [ion binding]; metal-binding site
344609001246	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
344609001247	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
344609001248	putative deacylase active site [active]
344609001249	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
344609001250	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
344609001251	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
344609001252	non-specific DNA binding site [nucleotide binding]; other site
344609001253	salt bridge; other site
344609001254	sequence-specific DNA binding site [nucleotide binding]; other site
344609001255	copper exporting ATPase; Provisional; Region: copA; PRK10671
344609001256	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
344609001257	metal-binding site [ion binding]
344609001258	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
344609001259	metal-binding site [ion binding]
344609001260	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
344609001261	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609001262	motif II; other site
344609001263	glutaminase; Reviewed; Region: PRK12356
344609001264	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
344609001265	amino acid transporter; Region: 2A0306; TIGR00909
344609001266	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
344609001267	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
344609001268	DNA binding residues [nucleotide binding]
344609001269	dimer interface [polypeptide binding]; other site
344609001270	copper binding site [ion binding]; other site
344609001271	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
344609001272	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
344609001273	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
344609001274	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
344609001275	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609001276	Walker A/P-loop; other site
344609001277	ATP binding site [chemical binding]; other site
344609001278	Q-loop/lid; other site
344609001279	ABC transporter signature motif; other site
344609001280	Walker B; other site
344609001281	D-loop; other site
344609001282	H-loop/switch region; other site
344609001283	Uncharacterized protein family (UPF0014); Region: UPF0014; pfam03649
344609001284	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
344609001285	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
344609001286	oxidoreductase; Provisional; Region: PRK08017
344609001287	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
344609001288	NADP binding site [chemical binding]; other site
344609001289	active site
344609001290	steroid binding site; other site
344609001291	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
344609001292	active site
344609001293	catalytic triad [active]
344609001294	oxyanion hole [active]
344609001295	switch loop; other site
344609001296	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
344609001297	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
344609001298	Walker A/P-loop; other site
344609001299	ATP binding site [chemical binding]; other site
344609001300	Q-loop/lid; other site
344609001301	ABC transporter signature motif; other site
344609001302	Walker B; other site
344609001303	D-loop; other site
344609001304	H-loop/switch region; other site
344609001305	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
344609001306	FtsX-like permease family; Region: FtsX; pfam02687
344609001307	FtsX-like permease family; Region: FtsX; pfam02687
344609001308	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001309	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
344609001310	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
344609001311	active site residue [active]
344609001312	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
344609001313	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609001314	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
344609001315	dimerization interface [polypeptide binding]; other site
344609001316	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
344609001317	ureidoglycolate hydrolase; Provisional; Region: PRK03606
344609001318	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
344609001319	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
344609001320	Bacterial transcriptional regulator; Region: IclR; pfam01614
344609001321	glyoxylate carboligase; Provisional; Region: PRK11269
344609001322	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
344609001323	PYR/PP interface [polypeptide binding]; other site
344609001324	dimer interface [polypeptide binding]; other site
344609001325	TPP binding site [chemical binding]; other site
344609001326	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
344609001327	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
344609001328	TPP-binding site [chemical binding]; other site
344609001329	hydroxypyruvate isomerase; Provisional; Region: PRK09997
344609001330	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001331	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
344609001332	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
344609001333	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
344609001334	homodimer interface [polypeptide binding]; other site
344609001335	NADP binding site [chemical binding]; other site
344609001336	substrate binding site [chemical binding]; other site
344609001337	ribosome-associated protein; Provisional; Region: PRK11507
344609001338	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
344609001339	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
344609001340	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
344609001341	active site
344609001342	HIGH motif; other site
344609001343	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
344609001344	KMSKS motif; other site
344609001345	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
344609001346	tRNA binding surface [nucleotide binding]; other site
344609001347	anticodon binding site; other site
344609001348	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
344609001349	substrate binding site [chemical binding]; other site
344609001350	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
344609001351	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
344609001352	putative active site [active]
344609001353	putative metal binding site [ion binding]; other site
344609001354	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
344609001355	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
344609001356	ATP-grasp domain; Region: ATP-grasp; pfam02222
344609001357	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
344609001358	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
344609001359	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001360	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001361	transcriptional regulator FimZ; Provisional; Region: PRK09935
344609001362	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609001363	active site
344609001364	phosphorylation site [posttranslational modification]
344609001365	intermolecular recognition site; other site
344609001366	dimerization interface [polypeptide binding]; other site
344609001367	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
344609001368	DNA binding residues [nucleotide binding]
344609001369	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001370	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
344609001371	HlyD family secretion protein; Region: HlyD_3; pfam13437
344609001372	phenylalanine transporter; Provisional; Region: PRK10249
344609001373	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
344609001374	Mechanosensitive ion channel; Region: MS_channel; pfam00924
344609001375	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
344609001376	dimer interface [polypeptide binding]; other site
344609001377	FMN binding site [chemical binding]; other site
344609001378	hypothetical protein; Provisional; Region: PRK10250
344609001379	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
344609001380	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609001381	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609001382	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609001383	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
344609001384	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
344609001385	Hok/gef family; Region: HOK_GEF; pfam01848
344609001386	Hok/gef family; Region: HOK_GEF; pfam01848
344609001387	Hok/gef family; Region: HOK_GEF; pfam01848
344609001388	Hok/gef family; Region: HOK_GEF; pfam01848
344609001389	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
344609001390	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
344609001391	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
344609001392	outer membrane receptor FepA; Provisional; Region: PRK13524
344609001393	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
344609001394	N-terminal plug; other site
344609001395	ligand-binding site [chemical binding]; other site
344609001396	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
344609001397	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
344609001398	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
344609001399	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
344609001400	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
344609001401	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
344609001402	acyl-activating enzyme (AAE) consensus motif; other site
344609001403	AMP binding site [chemical binding]; other site
344609001404	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
344609001405	LPS O-antigen length regulator; Provisional; Region: PRK10381
344609001406	Chain length determinant protein; Region: Wzz; pfam02706
344609001407	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
344609001408	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
344609001409	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
344609001410	Walker A/P-loop; other site
344609001411	ATP binding site [chemical binding]; other site
344609001412	Q-loop/lid; other site
344609001413	ABC transporter signature motif; other site
344609001414	Walker B; other site
344609001415	D-loop; other site
344609001416	H-loop/switch region; other site
344609001417	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
344609001418	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
344609001419	ABC-ATPase subunit  interface; other site
344609001420	dimer interface [polypeptide binding]; other site
344609001421	putative PBP binding regions; other site
344609001422	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
344609001423	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
344609001424	ABC-ATPase subunit  interface; other site
344609001425	dimer interface [polypeptide binding]; other site
344609001426	putative PBP binding regions; other site
344609001427	enterobactin exporter EntS; Provisional; Region: PRK10489
344609001428	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609001429	putative substrate translocation pore; other site
344609001430	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
344609001431	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
344609001432	siderophore binding site; other site
344609001433	isochorismate synthase EntC; Provisional; Region: PRK15016
344609001434	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
344609001435	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
344609001436	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
344609001437	acyl-activating enzyme (AAE) consensus motif; other site
344609001438	active site
344609001439	AMP binding site [chemical binding]; other site
344609001440	substrate binding site [chemical binding]; other site
344609001441	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
344609001442	hydrophobic substrate binding pocket; other site
344609001443	Isochorismatase family; Region: Isochorismatase; pfam00857
344609001444	active site
344609001445	conserved cis-peptide bond; other site
344609001446	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
344609001447	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
344609001448	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
344609001449	putative NAD(P) binding site [chemical binding]; other site
344609001450	active site
344609001451	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
344609001452	CoenzymeA binding site [chemical binding]; other site
344609001453	subunit interaction site [polypeptide binding]; other site
344609001454	PHB binding site; other site
344609001455	carbon starvation protein A; Provisional; Region: PRK15015
344609001456	Carbon starvation protein CstA; Region: CstA; pfam02554
344609001457	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
344609001458	Uncharacterized small protein [Function unknown]; Region: COG2879
344609001459	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
344609001460	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
344609001461	putative active site [active]
344609001462	metal binding site [ion binding]; metal-binding site
344609001463	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
344609001464	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001465	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
344609001466	ParB-like nuclease domain; Region: ParBc; pfam02195
344609001467	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001468	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609001469	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609001470	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609001471	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609001472	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609001473	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609001474	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609001475	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
344609001476	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
344609001477	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
344609001478	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
344609001479	dimer interface [polypeptide binding]; other site
344609001480	decamer (pentamer of dimers) interface [polypeptide binding]; other site
344609001481	catalytic triad [active]
344609001482	peroxidatic and resolving cysteines [active]
344609001483	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
344609001484	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
344609001485	catalytic residue [active]
344609001486	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
344609001487	catalytic residues [active]
344609001488	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
344609001489	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
344609001490	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
344609001491	Ligand Binding Site [chemical binding]; other site
344609001492	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
344609001493	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
344609001494	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
344609001495	B1 nucleotide binding pocket [chemical binding]; other site
344609001496	B2 nucleotide binding pocket [chemical binding]; other site
344609001497	CAS motifs; other site
344609001498	active site
344609001499	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
344609001500	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
344609001501	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
344609001502	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
344609001503	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
344609001504	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
344609001505	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
344609001506	putative active site [active]
344609001507	(T/H)XGH motif; other site
344609001508	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
344609001509	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609001510	active site
344609001511	phosphorylation site [posttranslational modification]
344609001512	intermolecular recognition site; other site
344609001513	dimerization interface [polypeptide binding]; other site
344609001514	Transcriptional regulator; Region: CitT; pfam12431
344609001515	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
344609001516	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
344609001517	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
344609001518	DNA-binding site [nucleotide binding]; DNA binding site
344609001519	RNA-binding motif; other site
344609001520	chromosome condensation membrane protein; Provisional; Region: PRK14196
344609001521	Predicted amidohydrolase [General function prediction only]; Region: COG0388
344609001522	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
344609001523	putative active site [active]
344609001524	catalytic triad [active]
344609001525	putative dimer interface [polypeptide binding]; other site
344609001526	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
344609001527	lipoyl synthase; Provisional; Region: PRK05481
344609001528	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
344609001529	FeS/SAM binding site; other site
344609001530	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001531	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001532	PAAR motif; Region: PAAR_motif; cl15808
344609001533	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
344609001534	RHS Repeat; Region: RHS_repeat; pfam05593
344609001535	RHS Repeat; Region: RHS_repeat; pfam05593
344609001536	RHS Repeat; Region: RHS_repeat; pfam05593
344609001537	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
344609001538	RHS Repeat; Region: RHS_repeat; pfam05593
344609001539	RHS Repeat; Region: RHS_repeat; pfam05593
344609001540	RHS protein; Region: RHS; pfam03527
344609001541	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
344609001542	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
344609001543	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
344609001544	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
344609001545	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
344609001546	sensor protein KdpD; Provisional; Region: PRK10490
344609001547	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
344609001548	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
344609001549	Ligand Binding Site [chemical binding]; other site
344609001550	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
344609001551	GAF domain; Region: GAF_3; pfam13492
344609001552	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609001553	dimer interface [polypeptide binding]; other site
344609001554	phosphorylation site [posttranslational modification]
344609001555	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609001556	ATP binding site [chemical binding]; other site
344609001557	Mg2+ binding site [ion binding]; other site
344609001558	G-X-G motif; other site
344609001559	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
344609001560	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609001561	active site
344609001562	phosphorylation site [posttranslational modification]
344609001563	intermolecular recognition site; other site
344609001564	dimerization interface [polypeptide binding]; other site
344609001565	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
344609001566	DNA binding site [nucleotide binding]
344609001567	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001568	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609001569	Transposase; Region: HTH_Tnp_1; pfam01527
344609001570	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001571	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
344609001572	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
344609001573	active site
344609001574	substrate binding site [chemical binding]; other site
344609001575	metal binding site [ion binding]; metal-binding site
344609001576	replication initiation regulator SeqA; Provisional; Region: PRK11187
344609001577	acyl-CoA esterase; Provisional; Region: PRK10673
344609001578	PGAP1-like protein; Region: PGAP1; pfam07819
344609001579	LexA regulated protein; Provisional; Region: PRK11675
344609001580	flavodoxin FldA; Validated; Region: PRK09267
344609001581	ferric uptake regulator; Provisional; Region: fur; PRK09462
344609001582	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
344609001583	metal binding site 2 [ion binding]; metal-binding site
344609001584	putative DNA binding helix; other site
344609001585	metal binding site 1 [ion binding]; metal-binding site
344609001586	dimer interface [polypeptide binding]; other site
344609001587	structural Zn2+ binding site [ion binding]; other site
344609001588	YbfN-like lipoprotein; Region: YbfN; pfam13982
344609001589	outer membrane porin, OprD family; Region: OprD; pfam03573
344609001590	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
344609001591	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
344609001592	active site
344609001593	HIGH motif; other site
344609001594	nucleotide binding site [chemical binding]; other site
344609001595	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
344609001596	KMSKS motif; other site
344609001597	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
344609001598	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
344609001599	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
344609001600	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
344609001601	active site turn [active]
344609001602	phosphorylation site [posttranslational modification]
344609001603	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
344609001604	HPr interaction site; other site
344609001605	glycerol kinase (GK) interaction site [polypeptide binding]; other site
344609001606	active site
344609001607	phosphorylation site [posttranslational modification]
344609001608	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
344609001609	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
344609001610	active site
344609001611	trimer interface [polypeptide binding]; other site
344609001612	allosteric site; other site
344609001613	active site lid [active]
344609001614	hexamer (dimer of trimers) interface [polypeptide binding]; other site
344609001615	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
344609001616	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
344609001617	active site
344609001618	dimer interface [polypeptide binding]; other site
344609001619	MarR family; Region: MarR; pfam01047
344609001620	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
344609001621	ROK family; Region: ROK; pfam00480
344609001622	UMP phosphatase; Provisional; Region: PRK10444
344609001623	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609001624	active site
344609001625	motif I; other site
344609001626	motif II; other site
344609001627	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609001628	asparagine synthetase B; Provisional; Region: asnB; PRK09431
344609001629	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
344609001630	active site
344609001631	dimer interface [polypeptide binding]; other site
344609001632	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
344609001633	Ligand Binding Site [chemical binding]; other site
344609001634	Molecular Tunnel; other site
344609001635	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
344609001636	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
344609001637	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
344609001638	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
344609001639	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
344609001640	FeS/SAM binding site; other site
344609001641	TRAM domain; Region: TRAM; pfam01938
344609001642	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
344609001643	PhoH-like protein; Region: PhoH; pfam02562
344609001644	metal-binding heat shock protein; Provisional; Region: PRK00016
344609001645	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
344609001646	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
344609001647	Transporter associated domain; Region: CorC_HlyC; smart01091
344609001648	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
344609001649	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
344609001650	putative active site [active]
344609001651	catalytic triad [active]
344609001652	putative dimer interface [polypeptide binding]; other site
344609001653	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
344609001654	Uncharacterized conserved protein [Function unknown]; Region: COG3391
344609001655	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
344609001656	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
344609001657	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
344609001658	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609001659	dimer interface [polypeptide binding]; other site
344609001660	conserved gate region; other site
344609001661	putative PBP binding loops; other site
344609001662	ABC-ATPase subunit interface; other site
344609001663	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
344609001664	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609001665	dimer interface [polypeptide binding]; other site
344609001666	conserved gate region; other site
344609001667	putative PBP binding loops; other site
344609001668	ABC-ATPase subunit interface; other site
344609001669	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
344609001670	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
344609001671	Walker A/P-loop; other site
344609001672	ATP binding site [chemical binding]; other site
344609001673	Q-loop/lid; other site
344609001674	ABC transporter signature motif; other site
344609001675	Walker B; other site
344609001676	D-loop; other site
344609001677	H-loop/switch region; other site
344609001678	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
344609001679	active site
344609001680	tetramer interface [polypeptide binding]; other site
344609001681	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
344609001682	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
344609001683	nucleotide binding site [chemical binding]; other site
344609001684	putative NEF/HSP70 interaction site [polypeptide binding]; other site
344609001685	SBD interface [polypeptide binding]; other site
344609001686	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
344609001687	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001688	Sel1-like repeats; Region: SEL1; smart00671
344609001689	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
344609001690	Sel1-like repeats; Region: SEL1; smart00671
344609001691	Sel1-like repeats; Region: SEL1; smart00671
344609001692	Sel1-like repeats; Region: SEL1; smart00671
344609001693	Sel1-like repeats; Region: SEL1; smart00671
344609001694	Sel1-like repeats; Region: SEL1; smart00671
344609001695	hypothetical protein; Provisional; Region: PRK11032
344609001696	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
344609001697	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
344609001698	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
344609001699	HIGH motif; other site
344609001700	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
344609001701	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
344609001702	active site
344609001703	KMSKS motif; other site
344609001704	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
344609001705	tRNA binding surface [nucleotide binding]; other site
344609001706	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
344609001707	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
344609001708	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
344609001709	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
344609001710	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
344609001711	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
344609001712	active site
344609001713	(T/H)XGH motif; other site
344609001714	ribosome-associated protein; Provisional; Region: PRK11538
344609001715	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
344609001716	penicillin-binding protein 2; Provisional; Region: PRK10795
344609001717	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
344609001718	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
344609001719	cell wall shape-determining protein; Provisional; Region: PRK10794
344609001720	rare lipoprotein A; Provisional; Region: PRK10672
344609001721	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
344609001722	Sporulation related domain; Region: SPOR; pfam05036
344609001723	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
344609001724	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
344609001725	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
344609001726	hypothetical protein; Provisional; Region: PRK04998
344609001727	lipoate-protein ligase B; Provisional; Region: PRK14342
344609001728	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001729	hypothetical protein; Provisional; Region: PRK10167
344609001730	Uncharacterized conserved protein [Function unknown]; Region: COG3272
344609001731	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
344609001732	DNA photolyase; Region: DNA_photolyase; pfam00875
344609001733	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
344609001734	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609001735	putative substrate translocation pore; other site
344609001736	POT family; Region: PTR2; pfam00854
344609001737	Uncharacterized conserved protein [Function unknown]; Region: COG0327
344609001738	metal-binding protein; Provisional; Region: PRK10799
344609001739	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
344609001740	sensor histidine kinase inhibitor, KipI family; Region: TIGR00370
344609001741	biotin-dependent carboxylase uncharacterized domain; Region: urea_amlyse_rel; TIGR00724
344609001742	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
344609001743	putative active site [active]
344609001744	endonuclease VIII; Provisional; Region: PRK10445
344609001745	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
344609001746	DNA binding site [nucleotide binding]
344609001747	catalytic residue [active]
344609001748	putative catalytic residues [active]
344609001749	H2TH interface [polypeptide binding]; other site
344609001750	intercalation triad [nucleotide binding]; other site
344609001751	substrate specificity determining residue; other site
344609001752	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
344609001753	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
344609001754	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
344609001755	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
344609001756	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
344609001757	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
344609001758	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
344609001759	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
344609001760	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
344609001761	PapC N-terminal domain; Region: PapC_N; pfam13954
344609001762	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
344609001763	PapC C-terminal domain; Region: PapC_C; pfam13953
344609001764	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001765	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
344609001766	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
344609001767	dimer interface [polypeptide binding]; other site
344609001768	active site
344609001769	citrylCoA binding site [chemical binding]; other site
344609001770	NADH binding [chemical binding]; other site
344609001771	cationic pore residues; other site
344609001772	oxalacetate/citrate binding site [chemical binding]; other site
344609001773	coenzyme A binding site [chemical binding]; other site
344609001774	catalytic triad [active]
344609001775	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
344609001776	Iron-sulfur protein interface; other site
344609001777	proximal quinone binding site [chemical binding]; other site
344609001778	SdhD (CybS) interface [polypeptide binding]; other site
344609001779	proximal heme binding site [chemical binding]; other site
344609001780	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
344609001781	SdhC subunit interface [polypeptide binding]; other site
344609001782	proximal heme binding site [chemical binding]; other site
344609001783	cardiolipin binding site; other site
344609001784	Iron-sulfur protein interface; other site
344609001785	proximal quinone binding site [chemical binding]; other site
344609001786	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
344609001787	L-aspartate oxidase; Provisional; Region: PRK06175
344609001788	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
344609001789	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
344609001790	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
344609001791	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
344609001792	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
344609001793	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
344609001794	TPP-binding site [chemical binding]; other site
344609001795	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
344609001796	dimer interface [polypeptide binding]; other site
344609001797	PYR/PP interface [polypeptide binding]; other site
344609001798	TPP binding site [chemical binding]; other site
344609001799	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
344609001800	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
344609001801	E3 interaction surface; other site
344609001802	lipoyl attachment site [posttranslational modification]; other site
344609001803	e3 binding domain; Region: E3_binding; pfam02817
344609001804	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
344609001805	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
344609001806	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
344609001807	CoA-ligase; Region: Ligase_CoA; pfam00549
344609001808	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
344609001809	CoA binding domain; Region: CoA_binding; smart00881
344609001810	CoA-ligase; Region: Ligase_CoA; pfam00549
344609001811	DNA-binding transcriptional repressor MngR; Provisional; Region: PRK09764
344609001812	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
344609001813	DNA-binding site [nucleotide binding]; DNA binding site
344609001814	UTRA domain; Region: UTRA; pfam07702
344609001815	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
344609001816	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
344609001817	active site
344609001818	phosphorylation site [posttranslational modification]
344609001819	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
344609001820	active site
344609001821	P-loop; other site
344609001822	phosphorylation site [posttranslational modification]
344609001823	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
344609001824	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001825	alpha-mannosidase; Provisional; Region: PRK09819
344609001826	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
344609001827	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
344609001828	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
344609001829	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
344609001830	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
344609001831	hypothetical protein; Provisional; Region: PRK10588
344609001832	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
344609001833	active site
344609001834	colicin uptake protein TolQ; Provisional; Region: PRK10801
344609001835	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
344609001836	colicin uptake protein TolR; Provisional; Region: PRK11024
344609001837	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
344609001838	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
344609001839	TolA C-terminal; Region: TolA; pfam06519
344609001840	translocation protein TolB; Provisional; Region: tolB; PRK03629
344609001841	TolB amino-terminal domain; Region: TolB_N; pfam04052
344609001842	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
344609001843	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
344609001844	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
344609001845	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
344609001846	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
344609001847	ligand binding site [chemical binding]; other site
344609001848	tol-pal system protein YbgF; Provisional; Region: PRK10803
344609001849	Tetratricopeptide repeat; Region: TPR_6; pfam13174
344609001850	Tetratricopeptide repeat; Region: TPR_6; pfam13174
344609001851	quinolinate synthetase; Provisional; Region: PRK09375
344609001852	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
344609001853	zinc transporter ZitB; Provisional; Region: PRK03557
344609001854	YbgS-like protein; Region: YbgS; pfam13985
344609001855	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
344609001856	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
344609001857	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
344609001858	catalytic core [active]
344609001859	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
344609001860	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
344609001861	active site
344609001862	catalytic residues [active]
344609001863	galactokinase; Provisional; Region: PRK05101
344609001864	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
344609001865	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
344609001866	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
344609001867	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
344609001868	dimer interface [polypeptide binding]; other site
344609001869	active site
344609001870	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
344609001871	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
344609001872	NAD binding site [chemical binding]; other site
344609001873	homodimer interface [polypeptide binding]; other site
344609001874	active site
344609001875	substrate binding site [chemical binding]; other site
344609001876	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
344609001877	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
344609001878	Walker A/P-loop; other site
344609001879	ATP binding site [chemical binding]; other site
344609001880	Q-loop/lid; other site
344609001881	ABC transporter signature motif; other site
344609001882	Walker B; other site
344609001883	D-loop; other site
344609001884	H-loop/switch region; other site
344609001885	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609001886	Walker A/P-loop; other site
344609001887	ATP binding site [chemical binding]; other site
344609001888	Q-loop/lid; other site
344609001889	ABC transporter signature motif; other site
344609001890	Walker B; other site
344609001891	D-loop; other site
344609001892	H-loop/switch region; other site
344609001893	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
344609001894	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
344609001895	molybdenum-pterin binding domain; Region: Mop; TIGR00638
344609001896	TOBE domain; Region: TOBE; pfam03459
344609001897	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
344609001898	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
344609001899	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
344609001900	substrate binding pocket [chemical binding]; other site
344609001901	membrane-bound complex binding site; other site
344609001902	hinge residues; other site
344609001903	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
344609001904	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609001905	putative PBP binding loops; other site
344609001906	ABC-ATPase subunit interface; other site
344609001907	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
344609001908	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609001909	Walker A/P-loop; other site
344609001910	ATP binding site [chemical binding]; other site
344609001911	Q-loop/lid; other site
344609001912	ABC transporter signature motif; other site
344609001913	Walker B; other site
344609001914	D-loop; other site
344609001915	H-loop/switch region; other site
344609001916	molybdenum-pterin binding domain; Region: Mop; TIGR00638
344609001917	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
344609001918	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609001919	motif II; other site
344609001920	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609001921	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
344609001922	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
344609001923	dimer interface [polypeptide binding]; other site
344609001924	active site
344609001925	Int/Topo IB signature motif; other site
344609001926	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609001927	Transposase; Region: HTH_Tnp_1; pfam01527
344609001928	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
344609001929	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
344609001930	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609001931	Transposase; Region: HTH_Tnp_1; pfam01527
344609001932	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609001933	HTH-like domain; Region: HTH_21; pfam13276
344609001934	Integrase core domain; Region: rve; pfam00665
344609001935	Integrase core domain; Region: rve_3; pfam13683
344609001936	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609001937	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609001938	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609001939	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609001940	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609001941	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609001942	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609001943	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609001944	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609001945	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609001946	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609001947	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609001948	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609001949	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609001950	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609001951	E3 ubiquitin-protein ligase SlrP; Provisional; Region: PRK15370
344609001952	Leucine-rich repeats, bacterial type; Region: LRR_BAC; smart00364
344609001953	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
344609001954	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609001955	Transposase; Region: HTH_Tnp_1; pfam01527
344609001956	Uncharacterized protein conserved in bacteria (DUF2135); Region: DUF2135; pfam09906
344609001957	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
344609001958	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609001959	dimer interface [polypeptide binding]; other site
344609001960	phosphorylation site [posttranslational modification]
344609001961	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609001962	ATP binding site [chemical binding]; other site
344609001963	Mg2+ binding site [ion binding]; other site
344609001964	G-X-G motif; other site
344609001965	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
344609001966	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609001967	active site
344609001968	phosphorylation site [posttranslational modification]
344609001969	intermolecular recognition site; other site
344609001970	dimerization interface [polypeptide binding]; other site
344609001971	transcriptional regulator RcsB; Provisional; Region: PRK10840
344609001972	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609001973	active site
344609001974	phosphorylation site [posttranslational modification]
344609001975	intermolecular recognition site; other site
344609001976	dimerization interface [polypeptide binding]; other site
344609001977	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
344609001978	DNA binding residues [nucleotide binding]
344609001979	dimerization interface [polypeptide binding]; other site
344609001980	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
344609001981	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609001982	ATP binding site [chemical binding]; other site
344609001983	G-X-G motif; other site
344609001984	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
344609001985	putative binding surface; other site
344609001986	active site
344609001987	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
344609001988	outer membrane porin protein C; Provisional; Region: PRK10554
344609001989	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
344609001990	ApbE family; Region: ApbE; pfam02424
344609001991	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
344609001992	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
344609001993	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609001994	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609001995	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
344609001996	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
344609001997	DNA binding site [nucleotide binding]
344609001998	active site
344609001999	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
344609002000	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
344609002001	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
344609002002	Walker A/P-loop; other site
344609002003	ATP binding site [chemical binding]; other site
344609002004	Q-loop/lid; other site
344609002005	ABC transporter signature motif; other site
344609002006	Walker B; other site
344609002007	D-loop; other site
344609002008	H-loop/switch region; other site
344609002009	malate:quinone oxidoreductase; Validated; Region: PRK05257
344609002010	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
344609002011	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
344609002012	secondary substrate binding site; other site
344609002013	primary substrate binding site; other site
344609002014	inhibition loop; other site
344609002015	dimerization interface [polypeptide binding]; other site
344609002016	tRNA synthetases class I (R); Region: tRNA-synt_1d; pfam00750
344609002017	ferredoxin-type protein; Provisional; Region: PRK10194
344609002018	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
344609002019	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
344609002020	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
344609002021	[4Fe-4S] binding site [ion binding]; other site
344609002022	molybdopterin cofactor binding site; other site
344609002023	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
344609002024	molybdopterin cofactor binding site; other site
344609002025	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
344609002026	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
344609002027	4Fe-4S binding domain; Region: Fer4_5; pfam12801
344609002028	4Fe-4S binding domain; Region: Fer4_6; pfam12837
344609002029	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
344609002030	cytochrome c-type protein NapC; Provisional; Region: PRK10617
344609002031	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
344609002032	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
344609002033	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
344609002034	Walker A/P-loop; other site
344609002035	ATP binding site [chemical binding]; other site
344609002036	Q-loop/lid; other site
344609002037	ABC transporter signature motif; other site
344609002038	Walker B; other site
344609002039	D-loop; other site
344609002040	H-loop/switch region; other site
344609002041	heme exporter protein CcmB; Region: ccmB; TIGR01190
344609002042	heme exporter protein CcmC; Region: ccmC; TIGR01191
344609002043	Heme exporter protein D (CcmD); Region: CcmD; cl11475
344609002044	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
344609002045	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
344609002046	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
344609002047	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
344609002048	catalytic residues [active]
344609002049	central insert; other site
344609002050	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
344609002051	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
344609002052	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
344609002053	binding surface
344609002054	TPR motif; other site
344609002055	transcriptional regulator NarP; Provisional; Region: PRK10403
344609002056	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609002057	active site
344609002058	phosphorylation site [posttranslational modification]
344609002059	intermolecular recognition site; other site
344609002060	dimerization interface [polypeptide binding]; other site
344609002061	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
344609002062	DNA binding residues [nucleotide binding]
344609002063	dimerization interface [polypeptide binding]; other site
344609002064	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002065	Pertactin; Region: Pertactin; pfam03212
344609002066	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
344609002067	Autotransporter beta-domain; Region: Autotransporter; pfam03797
344609002068	ProQ/FINO family; Region: ProQ; pfam04352
344609002069	putative RNA binding sites [nucleotide binding]; other site
344609002070	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
344609002071	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
344609002072	ssDNA binding site [nucleotide binding]; other site
344609002073	dimer interface [polypeptide binding]; other site
344609002074	tetramer (dimer of dimers) interface [polypeptide binding]; other site
344609002075	Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG5519
344609002076	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
344609002077	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
344609002078	BCCT family transporter; Region: BCCT; cl00569
344609002079	integrase; Provisional; Region: PRK09692
344609002080	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
344609002081	active site
344609002082	Int/Topo IB signature motif; other site
344609002083	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
344609002084	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
344609002085	Sulfatase; Region: Sulfatase; pfam00884
344609002086	hypothetical protein; Provisional; Region: PRK13689
344609002087	Nucleoid-associated protein [General function prediction only]; Region: COG3081
344609002088	nucleoid-associated protein NdpA; Validated; Region: PRK00378
344609002089	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
344609002090	5S rRNA interface [nucleotide binding]; other site
344609002091	CTC domain interface [polypeptide binding]; other site
344609002092	L16 interface [polypeptide binding]; other site
344609002093	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
344609002094	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
344609002095	ATP binding site [chemical binding]; other site
344609002096	putative Mg++ binding site [ion binding]; other site
344609002097	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
344609002098	nucleotide binding region [chemical binding]; other site
344609002099	ATP-binding site [chemical binding]; other site
344609002100	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
344609002101	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
344609002102	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
344609002103	RNA binding surface [nucleotide binding]; other site
344609002104	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
344609002105	active site
344609002106	uracil binding [chemical binding]; other site
344609002107	hypothetical protein; Provisional; Region: PRK11835
344609002108	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
344609002109	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
344609002110	Walker A/P-loop; other site
344609002111	ATP binding site [chemical binding]; other site
344609002112	Q-loop/lid; other site
344609002113	ABC transporter signature motif; other site
344609002114	Walker B; other site
344609002115	D-loop; other site
344609002116	H-loop/switch region; other site
344609002117	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
344609002118	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
344609002119	Walker A/P-loop; other site
344609002120	ATP binding site [chemical binding]; other site
344609002121	Q-loop/lid; other site
344609002122	ABC transporter signature motif; other site
344609002123	Walker B; other site
344609002124	D-loop; other site
344609002125	H-loop/switch region; other site
344609002126	microcin C ABC transporter permease; Provisional; Region: PRK15021
344609002127	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609002128	dimer interface [polypeptide binding]; other site
344609002129	conserved gate region; other site
344609002130	putative PBP binding loops; other site
344609002131	ABC-ATPase subunit interface; other site
344609002132	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
344609002133	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609002134	dimer interface [polypeptide binding]; other site
344609002135	conserved gate region; other site
344609002136	putative PBP binding loops; other site
344609002137	ABC-ATPase subunit interface; other site
344609002138	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
344609002139	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
344609002140	phage resistance protein; Provisional; Region: PRK10551
344609002141	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
344609002142	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
344609002143	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
344609002144	NlpC/P60 family; Region: NLPC_P60; pfam00877
344609002145	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
344609002146	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
344609002147	active site
344609002148	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
344609002149	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
344609002150	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
344609002151	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
344609002152	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
344609002153	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
344609002154	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
344609002155	elongation factor P; Provisional; Region: PRK04542
344609002156	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
344609002157	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
344609002158	RNA binding site [nucleotide binding]; other site
344609002159	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
344609002160	RNA binding site [nucleotide binding]; other site
344609002161	Flagellin N-methylase; Region: FliB; cl00497
344609002162	sugar efflux transporter B; Provisional; Region: PRK15011
344609002163	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609002164	putative substrate translocation pore; other site
344609002165	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
344609002166	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
344609002167	active site
344609002168	phosphorylation site [posttranslational modification]
344609002169	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
344609002170	dimerization domain swap beta strand [polypeptide binding]; other site
344609002171	regulatory protein interface [polypeptide binding]; other site
344609002172	active site
344609002173	regulatory phosphorylation site [posttranslational modification]; other site
344609002174	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
344609002175	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
344609002176	putative substrate binding site [chemical binding]; other site
344609002177	putative ATP binding site [chemical binding]; other site
344609002178	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
344609002179	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
344609002180	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
344609002181	active site
344609002182	P-loop; other site
344609002183	phosphorylation site [posttranslational modification]
344609002184	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
344609002185	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
344609002186	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
344609002187	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
344609002188	Nucleoside recognition; Region: Gate; pfam07670
344609002189	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
344609002190	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002191	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
344609002192	active site
344609002193	tetramer interface [polypeptide binding]; other site
344609002194	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
344609002195	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
344609002196	Nucleoside recognition; Region: Gate; pfam07670
344609002197	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
344609002198	putative kinase; Provisional; Region: PRK09954
344609002199	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
344609002200	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
344609002201	substrate binding site [chemical binding]; other site
344609002202	ATP binding site [chemical binding]; other site
344609002203	endonuclease IV; Provisional; Region: PRK01060
344609002204	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
344609002205	AP (apurinic/apyrimidinic) site pocket; other site
344609002206	DNA interaction; other site
344609002207	Metal-binding active site; metal-binding site
344609002208	conserved hypothetical integral membrane protein; Region: TIGR00698
344609002209	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
344609002210	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609002211	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
344609002212	putative dimerization interface [polypeptide binding]; other site
344609002213	lysine transporter; Provisional; Region: PRK10836
344609002214	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
344609002215	S-formylglutathione hydrolase; Region: PLN02442
344609002216	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
344609002217	homodecamer interface [polypeptide binding]; other site
344609002218	GTP cyclohydrolase I; Provisional; Region: PLN03044
344609002219	active site
344609002220	putative catalytic site residues [active]
344609002221	zinc binding site [ion binding]; other site
344609002222	GTP-CH-I/GFRP interaction surface; other site
344609002223	Predicted membrane protein [Function unknown]; Region: COG2311
344609002224	hypothetical protein; Provisional; Region: PRK10835
344609002225	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
344609002226	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
344609002227	ligand binding site [chemical binding]; other site
344609002228	calcium binding site [ion binding]; other site
344609002229	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
344609002230	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
344609002231	Walker A/P-loop; other site
344609002232	ATP binding site [chemical binding]; other site
344609002233	Q-loop/lid; other site
344609002234	ABC transporter signature motif; other site
344609002235	Walker B; other site
344609002236	D-loop; other site
344609002237	H-loop/switch region; other site
344609002238	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609002239	Walker A/P-loop; other site
344609002240	ATP binding site [chemical binding]; other site
344609002241	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002242	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609002243	Q-loop/lid; other site
344609002244	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002245	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609002246	Walker B; other site
344609002247	D-loop; other site
344609002248	H-loop/switch region; other site
344609002249	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
344609002250	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
344609002251	TM-ABC transporter signature motif; other site
344609002252	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
344609002253	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
344609002254	homodimer interface [polypeptide binding]; other site
344609002255	active site
344609002256	FMN binding site [chemical binding]; other site
344609002257	substrate binding site [chemical binding]; other site
344609002258	4Fe-4S binding domain; Region: Fer4; pfam00037
344609002259	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
344609002260	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
344609002261	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
344609002262	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
344609002263	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
344609002264	putative active site [active]
344609002265	cytidine deaminase; Provisional; Region: PRK09027
344609002266	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
344609002267	active site
344609002268	catalytic motif [active]
344609002269	Zn binding site [ion binding]; other site
344609002270	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
344609002271	active site
344609002272	catalytic motif [active]
344609002273	Zn binding site [ion binding]; other site
344609002274	hypothetical protein; Provisional; Region: PRK10711
344609002275	hypothetical protein; Provisional; Region: PRK01821
344609002276	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
344609002277	oxidoreductase; Provisional; Region: PRK12743
344609002278	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
344609002279	NAD(P) binding site [chemical binding]; other site
344609002280	active site
344609002281	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
344609002282	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
344609002283	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
344609002284	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
344609002285	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
344609002286	D-lactate dehydrogenase; Provisional; Region: PRK11183
344609002287	FAD binding domain; Region: FAD_binding_4; pfam01565
344609002288	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
344609002289	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
344609002290	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
344609002291	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
344609002292	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609002293	dimer interface [polypeptide binding]; other site
344609002294	conserved gate region; other site
344609002295	ABC-ATPase subunit interface; other site
344609002296	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
344609002297	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
344609002298	Walker A/P-loop; other site
344609002299	ATP binding site [chemical binding]; other site
344609002300	Q-loop/lid; other site
344609002301	ABC transporter signature motif; other site
344609002302	Walker B; other site
344609002303	D-loop; other site
344609002304	H-loop/switch region; other site
344609002305	CBS domain; Region: CBS; pfam00571
344609002306	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
344609002307	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609002308	dimer interface [polypeptide binding]; other site
344609002309	conserved gate region; other site
344609002310	putative PBP binding loops; other site
344609002311	ABC-ATPase subunit interface; other site
344609002312	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609002313	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609002314	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609002315	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609002316	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609002317	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609002318	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609002319	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609002320	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
344609002321	Predicted integral membrane protein [Function unknown]; Region: COG5455
344609002322	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002323	Fimbrial protein; Region: Fimbrial; cl01416
344609002324	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
344609002325	antiporter inner membrane protein; Provisional; Region: PRK11670
344609002326	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
344609002327	Walker A motif; other site
344609002328	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
344609002329	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
344609002330	active site
344609002331	HIGH motif; other site
344609002332	KMSKS motif; other site
344609002333	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
344609002334	tRNA binding surface [nucleotide binding]; other site
344609002335	anticodon binding site; other site
344609002336	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
344609002337	dimer interface [polypeptide binding]; other site
344609002338	putative tRNA-binding site [nucleotide binding]; other site
344609002339	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
344609002340	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609002341	HTH-like domain; Region: HTH_21; pfam13276
344609002342	Integrase core domain; Region: rve; pfam00665
344609002343	Integrase core domain; Region: rve_3; pfam13683
344609002344	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609002345	Transposase; Region: HTH_Tnp_1; pfam01527
344609002346	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002347	Protein of unknown function (DUF1307); Region: DUF1307; cl01981
344609002348	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
344609002349	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
344609002350	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
344609002351	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
344609002352	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609002353	active site
344609002354	phosphorylation site [posttranslational modification]
344609002355	intermolecular recognition site; other site
344609002356	dimerization interface [polypeptide binding]; other site
344609002357	LytTr DNA-binding domain; Region: LytTR; pfam04397
344609002358	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
344609002359	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
344609002360	GAF domain; Region: GAF; pfam01590
344609002361	Histidine kinase; Region: His_kinase; pfam06580
344609002362	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609002363	ATP binding site [chemical binding]; other site
344609002364	Mg2+ binding site [ion binding]; other site
344609002365	G-X-G motif; other site
344609002366	DinI-like family; Region: DinI; pfam06183
344609002367	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
344609002368	trimer interface [polypeptide binding]; other site
344609002369	active site
344609002370	substrate binding site [chemical binding]; other site
344609002371	CoA binding site [chemical binding]; other site
344609002372	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
344609002373	Phage Tail Collar Domain; Region: Collar; pfam07484
344609002374	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
344609002375	Enterobacterial Ail/Lom protein; Region: Ail_Lom; pfam06316
344609002376	Phage-related protein, tail component [Function unknown]; Region: COG4733
344609002377	Putative phage tail protein; Region: Phage-tail_3; pfam13550
344609002378	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
344609002379	Interdomain contacts; other site
344609002380	Cytokine receptor motif; other site
344609002381	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
344609002382	Fibronectin type III protein; Region: DUF3672; pfam12421
344609002383	Phage-related protein, tail component [Function unknown]; Region: COG4723
344609002384	Phage-related protein [Function unknown]; Region: gp18; COG4672
344609002385	Phage-related protein [Function unknown]; Region: COG4718
344609002386	Phage-related minor tail protein [Function unknown]; Region: COG5281
344609002387	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
344609002388	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
344609002389	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
344609002390	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
344609002391	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
344609002392	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
344609002393	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
344609002394	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
344609002395	DNA packaging protein FI; Region: Packaging_FI; pfam14000
344609002396	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
344609002397	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
344609002398	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
344609002399	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
344609002400	tandem repeat interface [polypeptide binding]; other site
344609002401	oligomer interface [polypeptide binding]; other site
344609002402	active site residues [active]
344609002403	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
344609002404	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
344609002405	putative transposase OrfB; Reviewed; Region: PHA02517
344609002406	Integrase core domain; Region: rve; pfam00665
344609002407	Integrase core domain; Region: rve_3; pfam13683
344609002408	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609002409	Transposase; Region: HTH_Tnp_1; pfam01527
344609002410	bifunctional enterobactin receptor/adhesin protein; Provisional; Region: PRK13486
344609002411	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
344609002412	N-terminal plug; other site
344609002413	ligand-binding site [chemical binding]; other site
344609002414	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609002415	HTH-like domain; Region: HTH_21; pfam13276
344609002416	Integrase core domain; Region: rve; pfam00665
344609002417	Integrase core domain; Region: rve_3; pfam13683
344609002418	putative transposase OrfB; Reviewed; Region: PHA02517
344609002419	Integrase core domain; Region: rve; pfam00665
344609002420	Integrase core domain; Region: rve_3; pfam13683
344609002421	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609002422	Transposase; Region: HTH_Tnp_1; pfam01527
344609002423	Protein of unknown function (DUF826); Region: DUF826; pfam05696
344609002424	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609002425	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609002426	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609002427	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609002428	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609002429	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002430	zinc/cadmium-binding protein; Provisional; Region: PRK10306
344609002431	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
344609002432	TMAO/DMSO reductase; Reviewed; Region: PRK05363
344609002433	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
344609002434	Moco binding site; other site
344609002435	metal coordination site [ion binding]; other site
344609002436	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
344609002437	active site
344609002438	homotetramer interface [polypeptide binding]; other site
344609002439	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
344609002440	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609002441	active site
344609002442	phosphorylation site [posttranslational modification]
344609002443	intermolecular recognition site; other site
344609002444	dimerization interface [polypeptide binding]; other site
344609002445	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
344609002446	DNA binding site [nucleotide binding]
344609002447	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
344609002448	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609002449	dimer interface [polypeptide binding]; other site
344609002450	phosphorylation site [posttranslational modification]
344609002451	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609002452	ATP binding site [chemical binding]; other site
344609002453	Mg2+ binding site [ion binding]; other site
344609002454	G-X-G motif; other site
344609002455	chaperone protein HchA; Provisional; Region: PRK04155
344609002456	Type 1 glutamine amidotransferase (GATase1)-like domain found in Escherichia coli Hsp31 protein (EcHsp31); Region: GATase1_EcHsp31_like; cd03148
344609002457	dimer interface [polypeptide binding]; other site
344609002458	metal binding site [ion binding]; metal-binding site
344609002459	potential oxyanion hole; other site
344609002460	potential catalytic triad [active]
344609002461	conserved cys residue [active]
344609002462	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002463	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
344609002464	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
344609002465	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609002466	HTH-like domain; Region: HTH_21; pfam13276
344609002467	Integrase core domain; Region: rve; pfam00665
344609002468	Integrase core domain; Region: rve_3; pfam13683
344609002469	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
344609002470	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
344609002471	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
344609002472	Zn2+ binding site [ion binding]; other site
344609002473	Mg2+ binding site [ion binding]; other site
344609002474	DNA cytosine methylase; Provisional; Region: PRK10458
344609002475	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
344609002476	cofactor binding site; other site
344609002477	DNA binding site [nucleotide binding]
344609002478	substrate interaction site [chemical binding]; other site
344609002479	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
344609002480	additional DNA contacts [nucleotide binding]; other site
344609002481	mismatch recognition site; other site
344609002482	active site
344609002483	zinc binding site [ion binding]; other site
344609002484	DNA intercalation site [nucleotide binding]; other site
344609002485	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
344609002486	EamA-like transporter family; Region: EamA; pfam00892
344609002487	Protein of unknown function (DUF3168); Region: DUF3168; pfam11367
344609002488	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
344609002489	Bacteriophage head-tail adaptor [General function prediction only]; Region: COG5614
344609002490	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
344609002491	Phage terminase, small subunit [DNA replication, recombination, and repair]; Region: XtmA; COG3728
344609002492	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
344609002493	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
344609002494	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
344609002495	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
344609002496	catalytic residues [active]
344609002497	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
344609002498	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609002499	Transposase; Region: HTH_Tnp_1; pfam01527
344609002500	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002501	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
344609002502	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
344609002503	putative acyl-acceptor binding pocket; other site
344609002504	putative peptidase; Provisional; Region: PRK11649
344609002505	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
344609002506	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
344609002507	Peptidase family M23; Region: Peptidase_M23; pfam01551
344609002508	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
344609002509	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
344609002510	metal binding site [ion binding]; metal-binding site
344609002511	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
344609002512	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
344609002513	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
344609002514	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
344609002515	ABC-ATPase subunit  interface; other site
344609002516	dimer interface [polypeptide binding]; other site
344609002517	putative PBP binding regions; other site
344609002518	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
344609002519	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609002520	Walker A motif; other site
344609002521	ATP binding site [chemical binding]; other site
344609002522	Walker B motif; other site
344609002523	arginine finger; other site
344609002524	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
344609002525	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
344609002526	RuvA N terminal domain; Region: RuvA_N; pfam01330
344609002527	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
344609002528	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002529	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
344609002530	Walker A motif; other site
344609002531	GTP binding site [chemical binding]; other site
344609002532	Walker B motif; other site
344609002533	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002534	Cobinamide kinase / cobinamide phosphate guanyltransferase; Region: CobU; cl17363
344609002535	cobalamin 5'-phosphate synthase/cobalamin synthase; Region: cobS; TIGR00317
344609002536	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
344609002537	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
344609002538	putative dimer interface [polypeptide binding]; other site
344609002539	active site pocket [active]
344609002540	putative cataytic base [active]
344609002541	L,D-transpeptidase; Provisional; Region: PRK10190
344609002542	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
344609002543	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
344609002544	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609002545	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
344609002546	putative dimerization interface [polypeptide binding]; other site
344609002547	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
344609002548	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609002549	The C-terminal substrate binding domain of LysR-type transcriptional regulator Cbl, which is required for expression of sulfate starvation-inducible (ssi) genes, contains the type 2 periplasmic binding fold; Region: PBP2_Cbl; cd08444
344609002550	putative substrate binding site [chemical binding]; other site
344609002551	dimerization interface [polypeptide binding]; other site
344609002552	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
344609002553	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002554	integrase; Provisional; Region: PRK09692
344609002555	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
344609002556	active site
344609002557	Int/Topo IB signature motif; other site
344609002558	hypothetical protein; Provisional; Region: PRK12378
344609002559	AMP nucleosidase; Provisional; Region: PRK08292
344609002560	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
344609002561	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
344609002562	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609002563	putative transposase OrfB; Reviewed; Region: PHA02517
344609002564	HTH-like domain; Region: HTH_21; pfam13276
344609002565	Integrase core domain; Region: rve; pfam00665
344609002566	Integrase core domain; Region: rve_3; pfam13683
344609002567	Transposase; Region: HTH_Tnp_1; cl17663
344609002568	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609002569	HTH-like domain; Region: HTH_21; pfam13276
344609002570	Integrase core domain; Region: rve; pfam00665
344609002571	Integrase core domain; Region: rve_3; pfam13683
344609002572	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
344609002573	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
344609002574	DNA binding site [nucleotide binding]
344609002575	Int/Topo IB signature motif; other site
344609002576	active site
344609002577	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002578	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609002579	Transposase; Region: HTH_Tnp_1; pfam01527
344609002580	putative transposase OrfB; Reviewed; Region: PHA02517
344609002581	Integrase core domain; Region: rve; pfam00665
344609002582	Integrase core domain; Region: rve_3; pfam13683
344609002583	Protein of unknown function (DUF968); Region: DUF968; pfam06147
344609002584	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609002585	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609002586	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609002587	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609002588	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609002589	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609002590	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609002591	Protein of unknown function (DUF968); Region: DUF968; pfam06147
344609002592	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609002593	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609002594	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609002595	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609002596	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609002597	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609002598	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609002599	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
344609002600	active site
344609002601	substrate binding site [chemical binding]; other site
344609002602	catalytic site [active]
344609002603	putative transposase OrfB; Reviewed; Region: PHA02517
344609002604	Integrase core domain; Region: rve; pfam00665
344609002605	Integrase core domain; Region: rve_3; pfam13683
344609002606	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609002607	Transposase; Region: HTH_Tnp_1; pfam01527
344609002608	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; pfam10076
344609002609	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
344609002610	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
344609002611	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
344609002612	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
344609002613	E3 ubiquitin-protein ligase SlrP; Provisional; Region: PRK15370
344609002614	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609002615	S-adenosylmethionine binding site [chemical binding]; other site
344609002616	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
344609002617	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609002618	Transposase; Region: HTH_Tnp_1; pfam01527
344609002619	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
344609002620	active site
344609002621	homotetramer interface [polypeptide binding]; other site
344609002622	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
344609002623	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
344609002624	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
344609002625	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
344609002626	TM-ABC transporter signature motif; other site
344609002627	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
344609002628	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
344609002629	Walker A/P-loop; other site
344609002630	ATP binding site [chemical binding]; other site
344609002631	Q-loop/lid; other site
344609002632	ABC transporter signature motif; other site
344609002633	Walker B; other site
344609002634	D-loop; other site
344609002635	H-loop/switch region; other site
344609002636	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
344609002637	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
344609002638	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
344609002639	ligand binding site [chemical binding]; other site
344609002640	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
344609002641	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
344609002642	Ferritin-like domain; Region: Ferritin; pfam00210
344609002643	ferroxidase diiron center [ion binding]; other site
344609002644	probable metal-binding protein; Region: matur_matur; TIGR03853
344609002645	tyrosine transporter TyrP; Provisional; Region: PRK15132
344609002646	aromatic amino acid transport protein; Region: araaP; TIGR00837
344609002647	hypothetical protein; Provisional; Region: PRK10396
344609002648	yecA family protein; Region: ygfB_yecA; TIGR02292
344609002649	SEC-C motif; Region: SEC-C; pfam02810
344609002650	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
344609002651	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
344609002652	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
344609002653	GIY-YIG motif/motif A; other site
344609002654	active site
344609002655	catalytic site [active]
344609002656	putative DNA binding site [nucleotide binding]; other site
344609002657	metal binding site [ion binding]; metal-binding site
344609002658	UvrB/uvrC motif; Region: UVR; pfam02151
344609002659	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
344609002660	Helix-hairpin-helix motif; Region: HHH; pfam00633
344609002661	response regulator; Provisional; Region: PRK09483
344609002662	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609002663	active site
344609002664	phosphorylation site [posttranslational modification]
344609002665	intermolecular recognition site; other site
344609002666	dimerization interface [polypeptide binding]; other site
344609002667	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
344609002668	DNA binding residues [nucleotide binding]
344609002669	dimerization interface [polypeptide binding]; other site
344609002670	hypothetical protein; Provisional; Region: PRK10613
344609002671	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
344609002672	Autoinducer binding domain; Region: Autoind_bind; pfam03472
344609002673	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
344609002674	DNA binding residues [nucleotide binding]
344609002675	dimerization interface [polypeptide binding]; other site
344609002676	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
344609002677	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
344609002678	Walker A/P-loop; other site
344609002679	ATP binding site [chemical binding]; other site
344609002680	Q-loop/lid; other site
344609002681	ABC transporter signature motif; other site
344609002682	Walker B; other site
344609002683	D-loop; other site
344609002684	H-loop/switch region; other site
344609002685	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
344609002686	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609002687	dimer interface [polypeptide binding]; other site
344609002688	conserved gate region; other site
344609002689	putative PBP binding loops; other site
344609002690	ABC-ATPase subunit interface; other site
344609002691	D-cysteine desulfhydrase; Validated; Region: PRK03910
344609002692	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
344609002693	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609002694	catalytic residue [active]
344609002695	cystine transporter subunit; Provisional; Region: PRK11260
344609002696	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
344609002697	substrate binding pocket [chemical binding]; other site
344609002698	membrane-bound complex binding site; other site
344609002699	hinge residues; other site
344609002700	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
344609002701	flagellin; Validated; Region: PRK08026
344609002702	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
344609002703	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
344609002704	flagellar capping protein; Reviewed; Region: fliD; PRK08032
344609002705	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
344609002706	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
344609002707	Flagellar protein FliS; Region: FliS; cl00654
344609002708	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
344609002709	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
344609002710	active site
344609002711	Na/Ca binding site [ion binding]; other site
344609002712	catalytic site [active]
344609002713	lipoprotein; Provisional; Region: PRK10397
344609002714	putative inner membrane protein; Provisional; Region: PRK11099
344609002715	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
344609002716	CPxP  motif; other site
344609002717	hypothetical protein; Provisional; Region: PRK09951
344609002718	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
344609002719	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
344609002720	Probable transposase; Region: OrfB_IS605; pfam01385
344609002721	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
344609002722	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002723	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
344609002724	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
344609002725	flagellar motor switch protein; Validated; Region: fliN; PRK05698
344609002726	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
344609002727	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
344609002728	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
344609002729	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
344609002730	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
344609002731	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
344609002732	DNA binding residues [nucleotide binding]
344609002733	dimerization interface [polypeptide binding]; other site
344609002734	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002735	hypothetical protein; Provisional; Region: PRK10708
344609002736	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
344609002737	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
344609002738	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609002739	active site
344609002740	motif I; other site
344609002741	motif II; other site
344609002742	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
344609002743	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
344609002744	metal binding site [ion binding]; metal-binding site
344609002745	active site
344609002746	I-site; other site
344609002747	hypothetical protein; Provisional; Region: PRK10062
344609002748	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002749	Immunoglobulin domain; Region: Ig_2; pfam13895
344609002750	Phage tail assembly chaperone; Region: Phage_TAC; pfam06222
344609002751	Protein of unknown function (DUF4035); Region: DUF4035; pfam13227
344609002752	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609002753	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609002754	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609002755	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609002756	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609002757	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609002758	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609002759	Phage-related protein [Function unknown]; Region: COG4718
344609002760	Phage-related protein [Function unknown]; Region: gp18; COG4672
344609002761	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
344609002762	MPN+ (JAMM) motif; other site
344609002763	Zinc-binding site [ion binding]; other site
344609002764	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
344609002765	NlpC/P60 family; Region: NLPC_P60; cl17555
344609002766	Phage-related protein, tail component [Function unknown]; Region: COG4723
344609002767	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
344609002768	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
344609002769	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
344609002770	Phage tail fibre adhesin Gp38; Region: GP38; pfam05268
344609002771	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
344609002772	DinI-like family; Region: DinI; pfam06183
344609002773	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609002774	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609002775	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
344609002776	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
344609002777	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
344609002778	dimer interface [polypeptide binding]; other site
344609002779	anticodon binding site; other site
344609002780	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
344609002781	homodimer interface [polypeptide binding]; other site
344609002782	motif 1; other site
344609002783	active site
344609002784	motif 2; other site
344609002785	GAD domain; Region: GAD; pfam02938
344609002786	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
344609002787	motif 3; other site
344609002788	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
344609002789	nudix motif; other site
344609002790	hypothetical protein; Validated; Region: PRK00110
344609002791	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
344609002792	active site
344609002793	putative DNA-binding cleft [nucleotide binding]; other site
344609002794	dimer interface [polypeptide binding]; other site
344609002795	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
344609002796	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002797	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609002798	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609002799	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609002800	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609002801	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609002802	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609002803	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609002804	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609002805	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609002806	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609002807	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609002808	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609002809	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609002810	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609002811	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609002812	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609002813	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609002814	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609002815	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609002816	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609002817	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609002818	HTH-like domain; Region: HTH_21; pfam13276
344609002819	Integrase core domain; Region: rve; pfam00665
344609002820	Integrase core domain; Region: rve_3; pfam13683
344609002821	Domain of unknown function (DUF932); Region: DUF932; pfam06067
344609002822	Antirestriction protein; Region: Antirestrict; pfam03230
344609002823	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
344609002824	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
344609002825	MPN+ (JAMM) motif; other site
344609002826	Zinc-binding site [ion binding]; other site
344609002827	Protein of unknown function (DUF987); Region: DUF987; pfam06174
344609002828	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
344609002829	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
344609002830	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609002831	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609002832	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609002833	High-affinity nickel-transport protein; Region: NicO; cl00964
344609002834	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
344609002835	putative metal binding site [ion binding]; other site
344609002836	putative homodimer interface [polypeptide binding]; other site
344609002837	putative homotetramer interface [polypeptide binding]; other site
344609002838	putative homodimer-homodimer interface [polypeptide binding]; other site
344609002839	putative allosteric switch controlling residues; other site
344609002840	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
344609002841	substrate binding site [chemical binding]; other site
344609002842	multimerization interface [polypeptide binding]; other site
344609002843	ATP binding site [chemical binding]; other site
344609002844	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
344609002845	dimer interface [polypeptide binding]; other site
344609002846	substrate binding site [chemical binding]; other site
344609002847	ATP binding site [chemical binding]; other site
344609002848	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
344609002849	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
344609002850	active site
344609002851	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
344609002852	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
344609002853	DNA-binding site [nucleotide binding]; DNA binding site
344609002854	UTRA domain; Region: UTRA; pfam07702
344609002855	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
344609002856	YegV-like sugar kinase.  Found only in bacteria, YegV-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YegV_kinase_like; cd01944
344609002857	substrate binding site [chemical binding]; other site
344609002858	ATP binding site [chemical binding]; other site
344609002859	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
344609002860	nucleoside transporter; Region: 2A0110; TIGR00889
344609002861	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609002862	putative substrate translocation pore; other site
344609002863	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
344609002864	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
344609002865	putative active site; other site
344609002866	catalytic residue [active]
344609002867	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
344609002868	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
344609002869	intersubunit interface [polypeptide binding]; other site
344609002870	active site
344609002871	zinc binding site [ion binding]; other site
344609002872	Na+ binding site [ion binding]; other site
344609002873	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
344609002874	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
344609002875	active site
344609002876	phosphorylation site [posttranslational modification]
344609002877	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
344609002878	active site
344609002879	P-loop; other site
344609002880	phosphorylation site [posttranslational modification]
344609002881	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
344609002882	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
344609002883	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
344609002884	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
344609002885	putative NAD(P) binding site [chemical binding]; other site
344609002886	catalytic Zn binding site [ion binding]; other site
344609002887	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
344609002888	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
344609002889	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
344609002890	lipid kinase; Reviewed; Region: PRK13054
344609002891	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
344609002892	putative protease; Provisional; Region: PRK15452
344609002893	Peptidase family U32; Region: Peptidase_U32; pfam01136
344609002894	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
344609002895	putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606
344609002896	Uncharacterized conserved protein [Function unknown]; Region: COG3422
344609002897	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
344609002898	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
344609002899	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609002900	active site
344609002901	phosphorylation site [posttranslational modification]
344609002902	intermolecular recognition site; other site
344609002903	dimerization interface [polypeptide binding]; other site
344609002904	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
344609002905	DNA binding site [nucleotide binding]
344609002906	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
344609002907	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
344609002908	dimerization interface [polypeptide binding]; other site
344609002909	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609002910	dimer interface [polypeptide binding]; other site
344609002911	phosphorylation site [posttranslational modification]
344609002912	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609002913	ATP binding site [chemical binding]; other site
344609002914	Mg2+ binding site [ion binding]; other site
344609002915	G-X-G motif; other site
344609002916	putative transporter; Provisional; Region: PRK10504
344609002917	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609002918	putative substrate translocation pore; other site
344609002919	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609002920	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
344609002921	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
344609002922	Protein export membrane protein; Region: SecD_SecF; cl14618
344609002923	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
344609002924	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
344609002925	HlyD family secretion protein; Region: HlyD_3; pfam13437
344609002926	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
344609002927	metal ion-dependent adhesion site (MIDAS); other site
344609002928	Protein phosphatase 2C; Region: PP2C_2; pfam13672
344609002929	Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only]; Region: COG4248
344609002930	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
344609002931	substrate binding site [chemical binding]; other site
344609002932	activation loop (A-loop); other site
344609002933	Y-family of DNA polymerases; Region: PolY; cl12025
344609002934	putative chaperone; Provisional; Region: PRK11678
344609002935	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
344609002936	nucleotide binding site [chemical binding]; other site
344609002937	putative NEF/HSP70 interaction site [polypeptide binding]; other site
344609002938	SBD interface [polypeptide binding]; other site
344609002939	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
344609002940	AlkA N-terminal domain; Region: AlkA_N; smart01009
344609002941	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
344609002942	minor groove reading motif; other site
344609002943	helix-hairpin-helix signature motif; other site
344609002944	substrate binding pocket [chemical binding]; other site
344609002945	active site
344609002946	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
344609002947	putative diguanylate cyclase; Provisional; Region: PRK09776
344609002948	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
344609002949	putative active site [active]
344609002950	heme pocket [chemical binding]; other site
344609002951	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
344609002952	putative active site [active]
344609002953	heme pocket [chemical binding]; other site
344609002954	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
344609002955	putative active site [active]
344609002956	heme pocket [chemical binding]; other site
344609002957	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
344609002958	metal binding site [ion binding]; metal-binding site
344609002959	active site
344609002960	I-site; other site
344609002961	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
344609002962	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
344609002963	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
344609002964	ATP-binding site [chemical binding]; other site
344609002965	Sugar specificity; other site
344609002966	Pyrimidine base specificity; other site
344609002967	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
344609002968	trimer interface [polypeptide binding]; other site
344609002969	active site
344609002970	putative assembly protein; Provisional; Region: PRK10833
344609002971	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
344609002972	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
344609002973	FOG: CBS domain [General function prediction only]; Region: COG0517
344609002974	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
344609002975	Transporter associated domain; Region: CorC_HlyC; smart01091
344609002976	polysaccharide export protein Wza; Provisional; Region: PRK15078
344609002977	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
344609002978	SLBB domain; Region: SLBB; pfam10531
344609002979	Low molecular weight phosphatase family; Region: LMWPc; cd00115
344609002980	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
344609002981	active site
344609002982	tyrosine kinase; Provisional; Region: PRK11519
344609002983	Chain length determinant protein; Region: Wzz; pfam02706
344609002984	Chain length determinant protein; Region: Wzz; cl15801
344609002985	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
344609002986	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
344609002987	putative acyl transferase; Provisional; Region: PRK10191
344609002988	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
344609002989	trimer interface [polypeptide binding]; other site
344609002990	active site
344609002991	substrate binding site [chemical binding]; other site
344609002992	CoA binding site [chemical binding]; other site
344609002993	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
344609002994	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
344609002995	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
344609002996	putative glycosyl transferase; Provisional; Region: PRK10063
344609002997	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
344609002998	metal-binding site
344609002999	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
344609003000	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
344609003001	putative trimer interface [polypeptide binding]; other site
344609003002	putative active site [active]
344609003003	putative substrate binding site [chemical binding]; other site
344609003004	putative CoA binding site [chemical binding]; other site
344609003005	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
344609003006	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
344609003007	NADP-binding site; other site
344609003008	homotetramer interface [polypeptide binding]; other site
344609003009	substrate binding site [chemical binding]; other site
344609003010	homodimer interface [polypeptide binding]; other site
344609003011	active site
344609003012	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
344609003013	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
344609003014	NADP binding site [chemical binding]; other site
344609003015	active site
344609003016	putative substrate binding site [chemical binding]; other site
344609003017	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
344609003018	active site
344609003019	GDP-Mannose binding site [chemical binding]; other site
344609003020	dimer interface [polypeptide binding]; other site
344609003021	modified nudix motif
344609003022	metal binding site [ion binding]; metal-binding site
344609003023	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
344609003024	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
344609003025	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
344609003026	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
344609003027	Substrate binding site; other site
344609003028	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
344609003029	phosphomannomutase CpsG; Provisional; Region: PRK15414
344609003030	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
344609003031	active site
344609003032	substrate binding site [chemical binding]; other site
344609003033	metal binding site [ion binding]; metal-binding site
344609003034	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
344609003035	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
344609003036	colanic acid exporter; Provisional; Region: PRK10459
344609003037	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
344609003038	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
344609003039	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
344609003040	colanic acid biosynthesis glycosyltransferase WcaL; Region: wcaL; TIGR04005
344609003041	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
344609003042	putative ADP-binding pocket [chemical binding]; other site
344609003043	putative colanic acid biosynthesis protein; Provisional; Region: wcaM; PRK10123
344609003044	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
344609003045	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
344609003046	putative NAD(P) binding site [chemical binding]; other site
344609003047	active site
344609003048	putative substrate binding site [chemical binding]; other site
344609003049	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
344609003050	active site
344609003051	tetramer interface; other site
344609003052	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
344609003053	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
344609003054	NAD binding site [chemical binding]; other site
344609003055	substrate binding site [chemical binding]; other site
344609003056	homodimer interface [polypeptide binding]; other site
344609003057	active site
344609003058	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
344609003059	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
344609003060	NADP binding site [chemical binding]; other site
344609003061	active site
344609003062	putative substrate binding site [chemical binding]; other site
344609003063	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
344609003064	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
344609003065	substrate binding site; other site
344609003066	tetramer interface; other site
344609003067	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
344609003068	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
344609003069	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
344609003070	Glycosyl hydrolase family 99-like domain of WbsX-like glycosyltransferases; Region: Glyco_tran_WbsX; cd11579
344609003071	putative ligand binding site [chemical binding]; other site
344609003072	putative catalytic site [active]
344609003073	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
344609003074	active site
344609003075	L-rhamnosyltransferase; Region: rhamnosyltran; TIGR01556
344609003076	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
344609003077	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
344609003078	putative ADP-binding pocket [chemical binding]; other site
344609003079	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
344609003080	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
344609003081	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
344609003082	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
344609003083	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
344609003084	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
344609003085	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
344609003086	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
344609003087	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
344609003088	putative NAD(P) binding site [chemical binding]; other site
344609003089	active site
344609003090	putative substrate binding site [chemical binding]; other site
344609003091	chain length determinant protein WzzB; Provisional; Region: PRK15471
344609003092	Chain length determinant protein; Region: Wzz; pfam02706
344609003093	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
344609003094	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
344609003095	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
344609003096	metal binding site [ion binding]; metal-binding site
344609003097	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
344609003098	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
344609003099	substrate binding site [chemical binding]; other site
344609003100	glutamase interaction surface [polypeptide binding]; other site
344609003101	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
344609003102	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
344609003103	catalytic residues [active]
344609003104	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
344609003105	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
344609003106	putative active site [active]
344609003107	oxyanion strand; other site
344609003108	catalytic triad [active]
344609003109	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
344609003110	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609003111	active site
344609003112	motif I; other site
344609003113	motif II; other site
344609003114	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
344609003115	putative active site pocket [active]
344609003116	4-fold oligomerization interface [polypeptide binding]; other site
344609003117	metal binding residues [ion binding]; metal-binding site
344609003118	3-fold/trimer interface [polypeptide binding]; other site
344609003119	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
344609003120	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
344609003121	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609003122	homodimer interface [polypeptide binding]; other site
344609003123	catalytic residue [active]
344609003124	Histidinol dehydrogenase; Region: Histidinol_dh; pfam00815
344609003125	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
344609003126	NAD binding site [chemical binding]; other site
344609003127	dimerization interface [polypeptide binding]; other site
344609003128	product binding site; other site
344609003129	substrate binding site [chemical binding]; other site
344609003130	zinc binding site [ion binding]; other site
344609003131	catalytic residues [active]
344609003132	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
344609003133	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
344609003134	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
344609003135	Histidine operon leader
344609003136	antitoxin YefM; Provisional; Region: PRK11409
344609003137	Plasmid encoded toxin Txe; Region: Plasmid_Txe; pfam06769
344609003138	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
344609003139	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
344609003140	putative NAD(P) binding site [chemical binding]; other site
344609003141	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609003142	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
344609003143	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
344609003144	dimerization interface [polypeptide binding]; other site
344609003145	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
344609003146	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
344609003147	CPxP  motif; other site
344609003148	exonuclease I; Provisional; Region: sbcB; PRK11779
344609003149	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
344609003150	active site
344609003151	catalytic site [active]
344609003152	substrate binding site [chemical binding]; other site
344609003153	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
344609003154	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609003155	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
344609003156	DNA gyrase inhibitor; Provisional; Region: PRK10016
344609003157	Predicted membrane protein [Function unknown]; Region: COG1289
344609003158	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
344609003159	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609003160	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609003161	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609003162	hypothetical protein; Provisional; Region: PRK05423
344609003163	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609003164	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609003165	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609003166	transcriptional regulator MirA; Provisional; Region: PRK15043
344609003167	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
344609003168	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609003169	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
344609003170	Protein of unknown function (DUF551); Region: DUF551; pfam04448
344609003171	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609003172	Transposase; Region: HTH_Tnp_1; pfam01527
344609003173	Transposase; Region: HTH_Tnp_1; cl17663
344609003174	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609003175	putative transposase OrfB; Reviewed; Region: PHA02517
344609003176	HTH-like domain; Region: HTH_21; pfam13276
344609003177	Integrase core domain; Region: rve; pfam00665
344609003178	Integrase core domain; Region: rve_3; pfam13683
344609003179	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
344609003180	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609003181	HTH-like domain; Region: HTH_21; pfam13276
344609003182	Integrase core domain; Region: rve; pfam00665
344609003183	Integrase core domain; Region: rve_3; pfam13683
344609003184	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
344609003185	non-specific DNA binding site [nucleotide binding]; other site
344609003186	salt bridge; other site
344609003187	sequence-specific DNA binding site [nucleotide binding]; other site
344609003188	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
344609003189	non-specific DNA binding site [nucleotide binding]; other site
344609003190	Predicted transcriptional regulator [Transcription]; Region: COG2932
344609003191	salt bridge; other site
344609003192	sequence-specific DNA binding site [nucleotide binding]; other site
344609003193	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
344609003194	Catalytic site [active]
344609003195	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
344609003196	Ash protein family; Region: Phage_ASH; pfam10554
344609003197	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
344609003198	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
344609003199	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
344609003200	Walker A motif; other site
344609003201	ATP binding site [chemical binding]; other site
344609003202	Walker B motif; other site
344609003203	arginine finger; other site
344609003204	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
344609003205	Antitermination protein; Region: Antiterm; pfam03589
344609003206	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
344609003207	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609003208	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
344609003209	DNA methylase; Region: N6_N4_Mtase; pfam01555
344609003210	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
344609003211	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
344609003212	Domain of unknown function (DUF303); Region: DUF303; pfam03629
344609003213	Protein of unknown function (DUF826); Region: DUF826; pfam05696
344609003214	Lysis protein S; Region: Lysis_S; pfam04971
344609003215	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
344609003216	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
344609003217	catalytic residues [active]
344609003218	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
344609003219	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
344609003220	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
344609003221	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609003222	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609003223	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609003224	putative transposase OrfB; Reviewed; Region: PHA02517
344609003225	Integrase core domain; Region: rve; pfam00665
344609003226	Integrase core domain; Region: rve_3; pfam13683
344609003227	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609003228	Transposase; Region: HTH_Tnp_1; pfam01527
344609003229	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609003230	Phage DNA packaging protein, Nu1 subunit of terminase [DNA replication, recombination, and repair]; Region: COG4220
344609003231	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609003232	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609003233	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609003234	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609003235	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609003236	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609003237	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609003238	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609003239	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
344609003240	gpW; Region: gpW; pfam02831
344609003241	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
344609003242	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
344609003243	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
344609003244	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
344609003245	tandem repeat interface [polypeptide binding]; other site
344609003246	oligomer interface [polypeptide binding]; other site
344609003247	active site residues [active]
344609003248	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
344609003249	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
344609003250	DNA packaging protein FI; Region: Packaging_FI; pfam14000
344609003251	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
344609003252	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
344609003253	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
344609003254	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
344609003255	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
344609003256	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
344609003257	phage tail assembly protein T; Region: phage_lam_T; TIGR01715
344609003258	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609003259	Transposase; Region: HTH_Tnp_1; pfam01527
344609003260	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
344609003261	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609003262	dimer interface [polypeptide binding]; other site
344609003263	conserved gate region; other site
344609003264	putative PBP binding loops; other site
344609003265	ABC-ATPase subunit interface; other site
344609003266	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
344609003267	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609003268	Walker A/P-loop; other site
344609003269	ATP binding site [chemical binding]; other site
344609003270	Q-loop/lid; other site
344609003271	ABC transporter signature motif; other site
344609003272	Walker B; other site
344609003273	D-loop; other site
344609003274	H-loop/switch region; other site
344609003275	TOBE domain; Region: TOBE_2; pfam08402
344609003276	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
344609003277	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
344609003278	metal binding site [ion binding]; metal-binding site
344609003279	dimer interface [polypeptide binding]; other site
344609003280	Uncharacterized conserved protein [Function unknown]; Region: COG2850
344609003281	Cupin-like domain; Region: Cupin_8; pfam13621
344609003282	sensor protein PhoQ; Provisional; Region: PRK10815
344609003283	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
344609003284	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
344609003285	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
344609003286	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609003287	ATP binding site [chemical binding]; other site
344609003288	Mg2+ binding site [ion binding]; other site
344609003289	G-X-G motif; other site
344609003290	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
344609003291	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609003292	active site
344609003293	phosphorylation site [posttranslational modification]
344609003294	intermolecular recognition site; other site
344609003295	dimerization interface [polypeptide binding]; other site
344609003296	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
344609003297	DNA binding site [nucleotide binding]
344609003298	adenylosuccinate lyase; Provisional; Region: PRK09285
344609003299	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
344609003300	tetramer interface [polypeptide binding]; other site
344609003301	active site
344609003302	putative lysogenization regulator; Reviewed; Region: PRK00218
344609003303	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
344609003304	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
344609003305	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
344609003306	nudix motif; other site
344609003307	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
344609003308	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
344609003309	probable active site [active]
344609003310	isocitrate dehydrogenase; Validated; Region: PRK07362
344609003311	isocitrate dehydrogenase; Reviewed; Region: PRK07006
344609003312	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
344609003313	transcriptional regulator MirA; Provisional; Region: PRK15043
344609003314	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
344609003315	DNA binding residues [nucleotide binding]
344609003316	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609003317	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609003318	HTH-like domain; Region: HTH_21; pfam13276
344609003319	Integrase core domain; Region: rve; pfam00665
344609003320	Integrase core domain; Region: rve_3; pfam13683
344609003321	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
344609003322	cell division inhibitor MinD; Provisional; Region: PRK10818
344609003323	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
344609003324	Switch I; other site
344609003325	Switch II; other site
344609003326	septum formation inhibitor; Reviewed; Region: minC; PRK03511
344609003327	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
344609003328	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
344609003329	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
344609003330	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
344609003331	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609003332	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
344609003333	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
344609003334	hypothetical protein; Provisional; Region: PRK10691
344609003335	hypothetical protein; Provisional; Region: PRK05170
344609003336	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
344609003337	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
344609003338	Catalytic site [active]
344609003339	disulfide bond formation protein B; Provisional; Region: PRK01749
344609003340	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
344609003341	transmembrane helices; other site
344609003342	fatty acid metabolism regulator; Provisional; Region: PRK04984
344609003343	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
344609003344	DNA-binding site [nucleotide binding]; DNA binding site
344609003345	FadR C-terminal domain; Region: FadR_C; pfam07840
344609003346	SpoVR family protein; Provisional; Region: PRK11767
344609003347	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
344609003348	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
344609003349	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
344609003350	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
344609003351	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
344609003352	TrkA-C domain; Region: TrkA_C; pfam02080
344609003353	Transporter associated domain; Region: CorC_HlyC; smart01091
344609003354	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
344609003355	dimer interface [polypeptide binding]; other site
344609003356	catalytic triad [active]
344609003357	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
344609003358	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
344609003359	N-acetyl-D-glucosamine binding site [chemical binding]; other site
344609003360	catalytic residue [active]
344609003361	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
344609003362	Flagellar regulator YcgR; Region: YcgR; pfam07317
344609003363	PilZ domain; Region: PilZ; pfam07238
344609003364	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
344609003365	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
344609003366	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3412
344609003367	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
344609003368	dimerization domain swap beta strand [polypeptide binding]; other site
344609003369	regulatory protein interface [polypeptide binding]; other site
344609003370	active site
344609003371	regulatory phosphorylation site [posttranslational modification]; other site
344609003372	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
344609003373	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
344609003374	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
344609003375	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
344609003376	Dak1 domain; Region: Dak1; pfam02733
344609003377	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
344609003378	PAS domain; Region: PAS; smart00091
344609003379	putative active site [active]
344609003380	heme pocket [chemical binding]; other site
344609003381	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609003382	Walker A motif; other site
344609003383	ATP binding site [chemical binding]; other site
344609003384	Walker B motif; other site
344609003385	arginine finger; other site
344609003386	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
344609003387	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609003388	Transposase; Region: HTH_Tnp_1; pfam01527
344609003389	putative transposase OrfB; Reviewed; Region: PHA02517
344609003390	Integrase core domain; Region: rve; pfam00665
344609003391	Integrase core domain; Region: rve_3; pfam13683
344609003392	GTP-binding protein YchF; Reviewed; Region: PRK09601
344609003393	YchF GTPase; Region: YchF; cd01900
344609003394	G1 box; other site
344609003395	GTP/Mg2+ binding site [chemical binding]; other site
344609003396	Switch I region; other site
344609003397	G2 box; other site
344609003398	Switch II region; other site
344609003399	G3 box; other site
344609003400	G4 box; other site
344609003401	G5 box; other site
344609003402	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
344609003403	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
344609003404	putative active site [active]
344609003405	catalytic residue [active]
344609003406	hypothetical protein; Provisional; Region: PRK10692
344609003407	putative transporter; Provisional; Region: PRK11660
344609003408	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
344609003409	Sulfate transporter family; Region: Sulfate_transp; pfam00916
344609003410	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
344609003411	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
344609003412	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
344609003413	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
344609003414	active site
344609003415	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
344609003416	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
344609003417	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
344609003418	outer membrane lipoprotein LolB; Region: lolB; TIGR00548
344609003419	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
344609003420	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
344609003421	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
344609003422	tRNA; other site
344609003423	putative tRNA binding site [nucleotide binding]; other site
344609003424	putative NADP binding site [chemical binding]; other site
344609003425	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
344609003426	peptide chain release factor 1; Validated; Region: prfA; PRK00591
344609003427	This domain is found in peptide chain release factors; Region: PCRF; smart00937
344609003428	RF-1 domain; Region: RF-1; pfam00472
344609003429	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
344609003430	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609003431	hypothetical protein; Provisional; Region: PRK10278
344609003432	hypothetical protein; Provisional; Region: PRK10941
344609003433	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
344609003434	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
344609003435	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
344609003436	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
344609003437	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
344609003438	cation transport regulator; Reviewed; Region: chaB; PRK09582
344609003439	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
344609003440	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
344609003441	putative active site pocket [active]
344609003442	dimerization interface [polypeptide binding]; other site
344609003443	putative catalytic residue [active]
344609003444	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
344609003445	putative invasin; Provisional; Region: PRK10177
344609003446	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
344609003447	transcriptional regulator NarL; Provisional; Region: PRK10651
344609003448	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609003449	active site
344609003450	phosphorylation site [posttranslational modification]
344609003451	intermolecular recognition site; other site
344609003452	dimerization interface [polypeptide binding]; other site
344609003453	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
344609003454	DNA binding residues [nucleotide binding]
344609003455	dimerization interface [polypeptide binding]; other site
344609003456	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
344609003457	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
344609003458	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
344609003459	dimerization interface [polypeptide binding]; other site
344609003460	Histidine kinase; Region: HisKA_3; pfam07730
344609003461	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609003462	ATP binding site [chemical binding]; other site
344609003463	Mg2+ binding site [ion binding]; other site
344609003464	G-X-G motif; other site
344609003465	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
344609003466	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
344609003467	4Fe-4S binding domain; Region: Fer4; cl02805
344609003468	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
344609003469	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
344609003470	RtT RNA
344609003471	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
344609003472	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
344609003473	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
344609003474	putative active site [active]
344609003475	putative substrate binding site [chemical binding]; other site
344609003476	putative cosubstrate binding site; other site
344609003477	catalytic site [active]
344609003478	SEC-C motif; Region: SEC-C; pfam02810
344609003479	hypothetical protein; Provisional; Region: PRK04233
344609003480	hypothetical protein; Provisional; Region: PRK10279
344609003481	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
344609003482	active site
344609003483	nucleophile elbow; other site
344609003484	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609003485	active site
344609003486	response regulator of RpoS; Provisional; Region: PRK10693
344609003487	phosphorylation site [posttranslational modification]
344609003488	intermolecular recognition site; other site
344609003489	dimerization interface [polypeptide binding]; other site
344609003490	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
344609003491	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
344609003492	active site
344609003493	tetramer interface; other site
344609003494	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
344609003495	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
344609003496	thymidine kinase; Provisional; Region: PRK04296
344609003497	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
344609003498	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
344609003499	putative catalytic cysteine [active]
344609003500	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
344609003501	putative active site [active]
344609003502	metal binding site [ion binding]; metal-binding site
344609003503	hypothetical protein; Provisional; Region: PRK11111
344609003504	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609003505	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
344609003506	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
344609003507	peptide binding site [polypeptide binding]; other site
344609003508	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
344609003509	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609003510	dimer interface [polypeptide binding]; other site
344609003511	conserved gate region; other site
344609003512	putative PBP binding loops; other site
344609003513	ABC-ATPase subunit interface; other site
344609003514	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
344609003515	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
344609003516	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609003517	dimer interface [polypeptide binding]; other site
344609003518	conserved gate region; other site
344609003519	ABC-ATPase subunit interface; other site
344609003520	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
344609003521	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
344609003522	Walker A/P-loop; other site
344609003523	ATP binding site [chemical binding]; other site
344609003524	Q-loop/lid; other site
344609003525	ABC transporter signature motif; other site
344609003526	Walker B; other site
344609003527	D-loop; other site
344609003528	H-loop/switch region; other site
344609003529	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
344609003530	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
344609003531	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
344609003532	Walker A/P-loop; other site
344609003533	ATP binding site [chemical binding]; other site
344609003534	Q-loop/lid; other site
344609003535	ABC transporter signature motif; other site
344609003536	Walker B; other site
344609003537	D-loop; other site
344609003538	H-loop/switch region; other site
344609003539	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
344609003540	dsDNA-mimic protein; Reviewed; Region: PRK05094
344609003541	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
344609003542	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
344609003543	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
344609003544	putative active site [active]
344609003545	catalytic site [active]
344609003546	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
344609003547	putative active site [active]
344609003548	catalytic site [active]
344609003549	voltage-gated potassium channel; Provisional; Region: PRK10537
344609003550	Ion channel; Region: Ion_trans_2; pfam07885
344609003551	TrkA-N domain; Region: TrkA_N; pfam02254
344609003552	YciI-like protein; Reviewed; Region: PRK11370
344609003553	transport protein TonB; Provisional; Region: PRK10819
344609003554	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
344609003555	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
344609003556	intracellular septation protein A; Reviewed; Region: PRK00259
344609003557	outer membrane protein W; Provisional; Region: PRK10959
344609003558	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
344609003559	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
344609003560	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
344609003561	dimer interface [polypeptide binding]; other site
344609003562	active site
344609003563	Int/Topo IB signature motif; other site
344609003564	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
344609003565	active site
344609003566	catalytic site [active]
344609003567	substrate binding site [chemical binding]; other site
344609003568	DicB protein; Region: DicB; pfam05358
344609003569	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
344609003570	transcriptional repressor DicA; Reviewed; Region: PRK09706
344609003571	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
344609003572	Helix-turn-helix domain; Region: HTH_36; pfam13730
344609003573	primosomal protein DnaI; Provisional; Region: PRK02854
344609003574	putative replication protein; Provisional; Region: PRK12377
344609003575	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609003576	Walker A motif; other site
344609003577	ATP binding site [chemical binding]; other site
344609003578	Walker B motif; other site
344609003579	arginine finger; other site
344609003580	Protein of unknown function (DUF1627); Region: DUF1627; pfam07789
344609003581	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
344609003582	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
344609003583	Protein of unknown function (DUF968); Region: DUF968; pfam06147
344609003584	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
344609003585	Antitermination protein; Region: Antiterm; pfam03589
344609003586	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
344609003587	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609003588	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
344609003589	DNA methylase; Region: N6_N4_Mtase; pfam01555
344609003590	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
344609003591	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
344609003592	Domain of unknown function (DUF303); Region: DUF303; pfam03629
344609003593	Lysis protein S; Region: Lysis_S; pfam04971
344609003594	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
344609003595	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
344609003596	catalytic residues [active]
344609003597	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
344609003598	Beta protein; Region: Beta_protein; pfam14350
344609003599	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
344609003600	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
344609003601	gpW; Region: gpW; pfam02831
344609003602	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
344609003603	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
344609003604	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
344609003605	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
344609003606	tandem repeat interface [polypeptide binding]; other site
344609003607	oligomer interface [polypeptide binding]; other site
344609003608	active site residues [active]
344609003609	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
344609003610	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
344609003611	DNA packaging protein FI; Region: Packaging_FI; pfam14000
344609003612	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
344609003613	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
344609003614	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
344609003615	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
344609003616	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
344609003617	Bacteriophage lambda minor tail protein (GpG); Region: Phage_lambd_GpG; pfam06894
344609003618	phage tail assembly protein T; Region: phage_lam_T; TIGR01715
344609003619	Phage-related minor tail protein [Function unknown]; Region: COG5281
344609003620	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
344609003621	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
344609003622	Phage-related protein [Function unknown]; Region: COG4718
344609003623	Phage-related protein [Function unknown]; Region: gp18; COG4672
344609003624	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
344609003625	MPN+ (JAMM) motif; other site
344609003626	Zinc-binding site [ion binding]; other site
344609003627	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
344609003628	NlpC/P60 family; Region: NLPC_P60; cl17555
344609003629	Phage-related protein, tail component [Function unknown]; Region: COG4723
344609003630	Phage-related protein, tail component [Function unknown]; Region: COG4733
344609003631	Putative phage tail protein; Region: Phage-tail_3; pfam13550
344609003632	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
344609003633	Fibronectin type III protein; Region: DUF3672; pfam12421
344609003634	Enterobacterial Ail/Lom protein; Region: Ail_Lom; pfam06316
344609003635	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
344609003636	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
344609003637	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
344609003638	Phage Tail Collar Domain; Region: Collar; pfam07484
344609003639	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
344609003640	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
344609003641	Methyltransferase domain; Region: Methyltransf_31; pfam13847
344609003642	Methyltransferase domain; Region: Methyltransf_12; pfam08242
344609003643	S-adenosylmethionine binding site [chemical binding]; other site
344609003644	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
344609003645	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
344609003646	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609003647	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
344609003648	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
344609003649	substrate binding site [chemical binding]; other site
344609003650	active site
344609003651	catalytic residues [active]
344609003652	heterodimer interface [polypeptide binding]; other site
344609003653	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
344609003654	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
344609003655	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609003656	catalytic residue [active]
344609003657	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
344609003658	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
344609003659	active site
344609003660	ribulose/triose binding site [chemical binding]; other site
344609003661	phosphate binding site [ion binding]; other site
344609003662	substrate (anthranilate) binding pocket [chemical binding]; other site
344609003663	product (indole) binding pocket [chemical binding]; other site
344609003664	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
344609003665	active site
344609003666	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
344609003667	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
344609003668	glutamine binding [chemical binding]; other site
344609003669	catalytic triad [active]
344609003670	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
344609003671	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
344609003672	anthranilate synthase component I; Provisional; Region: PRK13564
344609003673	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
344609003674	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
344609003675	Tryptophan operon leader
344609003676	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
344609003677	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
344609003678	active site
344609003679	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
344609003680	hypothetical protein; Provisional; Region: PRK11630
344609003681	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
344609003682	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
344609003683	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
344609003684	RNA binding surface [nucleotide binding]; other site
344609003685	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
344609003686	probable active site [active]
344609003687	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
344609003688	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
344609003689	NADP binding site [chemical binding]; other site
344609003690	homodimer interface [polypeptide binding]; other site
344609003691	active site
344609003692	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
344609003693	putative inner membrane peptidase; Provisional; Region: PRK11778
344609003694	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
344609003695	tandem repeat interface [polypeptide binding]; other site
344609003696	oligomer interface [polypeptide binding]; other site
344609003697	active site residues [active]
344609003698	hypothetical protein; Provisional; Region: PRK11037
344609003699	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
344609003700	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
344609003701	active site
344609003702	interdomain interaction site; other site
344609003703	putative metal-binding site [ion binding]; other site
344609003704	nucleotide binding site [chemical binding]; other site
344609003705	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
344609003706	domain I; other site
344609003707	DNA binding groove [nucleotide binding]
344609003708	phosphate binding site [ion binding]; other site
344609003709	domain II; other site
344609003710	domain III; other site
344609003711	nucleotide binding site [chemical binding]; other site
344609003712	catalytic site [active]
344609003713	domain IV; other site
344609003714	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
344609003715	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
344609003716	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
344609003717	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
344609003718	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609003719	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
344609003720	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609003721	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
344609003722	substrate binding site [chemical binding]; other site
344609003723	putative dimerization interface [polypeptide binding]; other site
344609003724	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
344609003725	dimerization interface [polypeptide binding]; other site
344609003726	active site
344609003727	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
344609003728	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
344609003729	active site
344609003730	Predicted membrane protein [Function unknown]; Region: COG3771
344609003731	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
344609003732	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
344609003733	TPR motif; other site
344609003734	binding surface
344609003735	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
344609003736	binding surface
344609003737	TPR motif; other site
344609003738	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
344609003739	active site
344609003740	dimer interface [polypeptide binding]; other site
344609003741	translation initiation factor Sui1; Validated; Region: PRK06824
344609003742	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
344609003743	putative rRNA binding site [nucleotide binding]; other site
344609003744	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609003745	lipoprotein; Provisional; Region: PRK10540
344609003746	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
344609003747	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
344609003748	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
344609003749	hypothetical protein; Provisional; Region: PRK13658
344609003750	RNase II stability modulator; Provisional; Region: PRK10060
344609003751	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
344609003752	putative active site [active]
344609003753	heme pocket [chemical binding]; other site
344609003754	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
344609003755	metal binding site [ion binding]; metal-binding site
344609003756	active site
344609003757	I-site; other site
344609003758	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
344609003759	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609003760	exoribonuclease II; Provisional; Region: PRK05054
344609003761	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
344609003762	RNB domain; Region: RNB; pfam00773
344609003763	S1 RNA binding domain; Region: S1; pfam00575
344609003764	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
344609003765	Uncharacterized conserved protein [Function unknown]; Region: COG2128
344609003766	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
344609003767	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
344609003768	NAD binding site [chemical binding]; other site
344609003769	homotetramer interface [polypeptide binding]; other site
344609003770	homodimer interface [polypeptide binding]; other site
344609003771	substrate binding site [chemical binding]; other site
344609003772	active site
344609003773	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609003774	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609003775	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609003776	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609003777	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609003778	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609003779	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609003780	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
344609003781	putative active site [active]
344609003782	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
344609003783	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
344609003784	Walker A/P-loop; other site
344609003785	ATP binding site [chemical binding]; other site
344609003786	Q-loop/lid; other site
344609003787	ABC transporter signature motif; other site
344609003788	Walker B; other site
344609003789	D-loop; other site
344609003790	H-loop/switch region; other site
344609003791	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
344609003792	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
344609003793	Walker A/P-loop; other site
344609003794	ATP binding site [chemical binding]; other site
344609003795	Q-loop/lid; other site
344609003796	ABC transporter signature motif; other site
344609003797	Walker B; other site
344609003798	D-loop; other site
344609003799	H-loop/switch region; other site
344609003800	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
344609003801	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
344609003802	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
344609003803	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609003804	dimer interface [polypeptide binding]; other site
344609003805	conserved gate region; other site
344609003806	putative PBP binding loops; other site
344609003807	ABC-ATPase subunit interface; other site
344609003808	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
344609003809	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609003810	dimer interface [polypeptide binding]; other site
344609003811	conserved gate region; other site
344609003812	putative PBP binding loops; other site
344609003813	ABC-ATPase subunit interface; other site
344609003814	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
344609003815	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
344609003816	peptide binding site [polypeptide binding]; other site
344609003817	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
344609003818	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
344609003819	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
344609003820	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
344609003821	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
344609003822	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
344609003823	non-specific DNA binding site [nucleotide binding]; other site
344609003824	salt bridge; other site
344609003825	sequence-specific DNA binding site [nucleotide binding]; other site
344609003826	Cupin domain; Region: Cupin_2; pfam07883
344609003827	gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK09847
344609003828	Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112
344609003829	NAD(P) binding site [chemical binding]; other site
344609003830	catalytic residues [active]
344609003831	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
344609003832	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
344609003833	4-aminobutyrate transaminase; Provisional; Region: PRK09792
344609003834	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
344609003835	inhibitor-cofactor binding pocket; inhibition site
344609003836	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609003837	catalytic residue [active]
344609003838	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
344609003839	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609003840	Walker A motif; other site
344609003841	ATP binding site [chemical binding]; other site
344609003842	Walker B motif; other site
344609003843	arginine finger; other site
344609003844	phage shock protein PspA; Provisional; Region: PRK10698
344609003845	phage shock protein B; Provisional; Region: pspB; PRK09458
344609003846	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
344609003847	phage shock protein C; Region: phageshock_pspC; TIGR02978
344609003848	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
344609003849	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
344609003850	active site residue [active]
344609003851	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
344609003852	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609003853	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
344609003854	Transcriptional regulators [Transcription]; Region: PurR; COG1609
344609003855	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
344609003856	DNA binding site [nucleotide binding]
344609003857	domain linker motif; other site
344609003858	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
344609003859	putative dimerization interface [polypeptide binding]; other site
344609003860	putative ligand binding site [chemical binding]; other site
344609003861	Predicted ATPase [General function prediction only]; Region: COG3106
344609003862	Predicted membrane protein [Function unknown]; Region: COG3768
344609003863	TIGR01620 family protein; Region: hyp_HI0043
344609003864	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
344609003865	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
344609003866	putative aromatic amino acid binding site; other site
344609003867	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609003868	Walker A motif; other site
344609003869	ATP binding site [chemical binding]; other site
344609003870	Walker B motif; other site
344609003871	arginine finger; other site
344609003872	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
344609003873	dimer interface [polypeptide binding]; other site
344609003874	catalytic triad [active]
344609003875	peroxidatic and resolving cysteines [active]
344609003876	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
344609003877	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
344609003878	active site
344609003879	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
344609003880	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
344609003881	putative active site [active]
344609003882	Zn binding site [ion binding]; other site
344609003883	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
344609003884	NADH(P)-binding; Region: NAD_binding_10; pfam13460
344609003885	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609003886	Transposase; Region: HTH_Tnp_1; pfam01527
344609003887	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
344609003888	NADH(P)-binding; Region: NAD_binding_10; pfam13460
344609003889	NAD(P) binding site [chemical binding]; other site
344609003890	active site
344609003891	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
344609003892	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
344609003893	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609003894	HTH-like domain; Region: HTH_21; pfam13276
344609003895	Integrase core domain; Region: rve; pfam00665
344609003896	Integrase core domain; Region: rve_3; pfam13683
344609003897	Transcriptional regulator [Transcription]; Region: LysR; COG0583
344609003898	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609003899	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
344609003900	putative effector binding pocket; other site
344609003901	putative dimerization interface [polypeptide binding]; other site
344609003902	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
344609003903	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
344609003904	peptide binding site [polypeptide binding]; other site
344609003905	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
344609003906	Mechanosensitive ion channel; Region: MS_channel; pfam00924
344609003907	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609003908	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
344609003909	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
344609003910	ligand binding site [chemical binding]; other site
344609003911	flexible hinge region; other site
344609003912	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
344609003913	putative switch regulator; other site
344609003914	non-specific DNA interactions [nucleotide binding]; other site
344609003915	DNA binding site [nucleotide binding]
344609003916	sequence specific DNA binding site [nucleotide binding]; other site
344609003917	putative cAMP binding site [chemical binding]; other site
344609003918	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
344609003919	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
344609003920	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
344609003921	DNA binding site [nucleotide binding]
344609003922	active site
344609003923	AbgT putative transporter family; Region: ABG_transport; cl17431
344609003924	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609003925	AbgT putative transporter family; Region: ABG_transport; cl17431
344609003926	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
344609003927	amidohydrolase; Region: amidohydrolases; TIGR01891
344609003928	putative metal binding site [ion binding]; other site
344609003929	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791
344609003930	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609003931	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
344609003932	putative substrate binding pocket [chemical binding]; other site
344609003933	putative dimerization interface [polypeptide binding]; other site
344609003934	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609003935	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609003936	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609003937	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609003938	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609003939	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609003940	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609003941	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
344609003942	Smr domain; Region: Smr; pfam01713
344609003943	PAS domain S-box; Region: sensory_box; TIGR00229
344609003944	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
344609003945	putative active site [active]
344609003946	heme pocket [chemical binding]; other site
344609003947	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
344609003948	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
344609003949	metal binding site [ion binding]; metal-binding site
344609003950	active site
344609003951	I-site; other site
344609003952	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
344609003953	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
344609003954	Cl binding site [ion binding]; other site
344609003955	oligomer interface [polypeptide binding]; other site
344609003956	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
344609003957	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
344609003958	ATP binding site [chemical binding]; other site
344609003959	Mg++ binding site [ion binding]; other site
344609003960	motif III; other site
344609003961	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
344609003962	nucleotide binding region [chemical binding]; other site
344609003963	ATP-binding site [chemical binding]; other site
344609003964	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
344609003965	putative RNA binding site [nucleotide binding]; other site
344609003966	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
344609003967	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
344609003968	Ligand Binding Site [chemical binding]; other site
344609003969	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609003970	Transposase; Region: HTH_Tnp_1; pfam01527
344609003971	Transposase; Region: HTH_Tnp_1; cl17663
344609003972	putative transposase OrfB; Reviewed; Region: PHA02517
344609003973	HTH-like domain; Region: HTH_21; pfam13276
344609003974	Integrase core domain; Region: rve; pfam00665
344609003975	Integrase core domain; Region: rve_3; pfam13683
344609003976	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609003977	Transposase; Region: HTH_Tnp_1; pfam01527
344609003978	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1636
344609003979	Protein of unknown function (DUF1367); Region: DUF1367; pfam07105
344609003980	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609003981	Transposase; Region: HTH_Tnp_1; pfam01527
344609003982	putative transposase OrfB; Reviewed; Region: PHA02517
344609003983	Integrase core domain; Region: rve; pfam00665
344609003984	Integrase core domain; Region: rve_3; pfam13683
344609003985	Protein of unknown function (DUF1133); Region: DUF1133; pfam06576
344609003986	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609003987	Transposase; Region: HTH_Tnp_1; pfam01527
344609003988	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609003989	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609003990	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609003991	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609003992	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609003993	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609003994	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609003995	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609003996	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
344609003997	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
344609003998	ABC-ATPase subunit  interface; other site
344609003999	dimer interface [polypeptide binding]; other site
344609004000	putative PBP binding regions; other site
344609004001	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
344609004002	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
344609004003	ABC-ATPase subunit  interface; other site
344609004004	dimer interface [polypeptide binding]; other site
344609004005	putative PBP binding regions; other site
344609004006	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
344609004007	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
344609004008	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
344609004009	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
344609004010	metal binding site [ion binding]; metal-binding site
344609004011	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
344609004012	Ligand Binding Site [chemical binding]; other site
344609004013	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
344609004014	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
344609004015	trimer interface [polypeptide binding]; other site
344609004016	eyelet of channel; other site
344609004017	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
344609004018	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
344609004019	dimer interface [polypeptide binding]; other site
344609004020	PYR/PP interface [polypeptide binding]; other site
344609004021	TPP binding site [chemical binding]; other site
344609004022	substrate binding site [chemical binding]; other site
344609004023	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
344609004024	Domain of unknown function; Region: EKR; smart00890
344609004025	4Fe-4S binding domain; Region: Fer4_6; pfam12837
344609004026	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
344609004027	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
344609004028	TPP-binding site [chemical binding]; other site
344609004029	dimer interface [polypeptide binding]; other site
344609004030	heat-inducible protein; Provisional; Region: PRK10449
344609004031	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
344609004032	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
344609004033	putative ligand binding site [chemical binding]; other site
344609004034	putative NAD binding site [chemical binding]; other site
344609004035	catalytic site [active]
344609004036	hypothetical protein; Provisional; Region: PRK10695
344609004037	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
344609004038	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004039	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
344609004040	Cytidylyltransferase family; Region: CTP_transf_1; cl17467
344609004041	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004042	Cytidylyltransferase family; Region: CTP_transf_1; cl17467
344609004043	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004044	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
344609004045	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
344609004046	active site
344609004047	Dual specificity phosphatase, catalytic domain; Region: DSPc; smart00195
344609004048	active site
344609004049	catalytic residues [active]
344609004050	azoreductase; Reviewed; Region: PRK00170
344609004051	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
344609004052	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
344609004053	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
344609004054	ATP binding site [chemical binding]; other site
344609004055	putative Mg++ binding site [ion binding]; other site
344609004056	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
344609004057	nucleotide binding region [chemical binding]; other site
344609004058	ATP-binding site [chemical binding]; other site
344609004059	Helicase associated domain (HA2); Region: HA2; pfam04408
344609004060	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
344609004061	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
344609004062	Uncharacterized conserved protein [Function unknown]; Region: COG1434
344609004063	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
344609004064	putative active site [active]
344609004065	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
344609004066	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
344609004067	NAD binding site [chemical binding]; other site
344609004068	catalytic residues [active]
344609004069	substrate binding site [chemical binding]; other site
344609004070	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
344609004071	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
344609004072	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609004073	Transposase; Region: HTH_Tnp_1; pfam01527
344609004074	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609004075	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609004076	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609004077	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609004078	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609004079	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609004080	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609004081	cytochrome b561; Provisional; Region: PRK11513
344609004082	hypothetical protein; Provisional; Region: PRK10040
344609004083	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609004084	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609004085	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609004086	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609004087	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609004088	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609004089	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609004090	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
344609004091	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609004092	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
344609004093	dimerization interface [polypeptide binding]; other site
344609004094	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
344609004095	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
344609004096	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
344609004097	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
344609004098	hypothetical protein; Provisional; Region: PRK11415
344609004099	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
344609004100	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
344609004101	Coenzyme A binding pocket [chemical binding]; other site
344609004102	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
344609004103	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609004104	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609004105	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609004106	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609004107	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609004108	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609004109	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609004110	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
344609004111	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
344609004112	gating phenylalanine in ion channel; other site
344609004113	tellurite resistance protein TehB; Provisional; Region: PRK11207
344609004114	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609004115	S-adenosylmethionine binding site [chemical binding]; other site
344609004116	putative transposase OrfB; Reviewed; Region: PHA02517
344609004117	Integrase core domain; Region: rve; pfam00665
344609004118	Integrase core domain; Region: rve_3; pfam13683
344609004119	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609004120	Transposase; Region: HTH_Tnp_1; pfam01527
344609004121	putative transposase OrfB; Reviewed; Region: PHA02517
344609004122	HTH-like domain; Region: HTH_21; pfam13276
344609004123	Integrase core domain; Region: rve; pfam00665
344609004124	Integrase core domain; Region: rve_3; pfam13683
344609004125	Transposase; Region: HTH_Tnp_1; cl17663
344609004126	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609004127	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
344609004128	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609004129	Transposase; Region: HTH_Tnp_1; pfam01527
344609004130	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609004131	HTH-like domain; Region: HTH_21; pfam13276
344609004132	Integrase core domain; Region: rve; pfam00665
344609004133	Integrase core domain; Region: rve_3; pfam13683
344609004134	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004135	hypothetical protein; Provisional; Region: PRK10106
344609004136	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
344609004137	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609004138	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
344609004139	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
344609004140	inner membrane protein; Provisional; Region: PRK10995
344609004141	putative arabinose transporter; Provisional; Region: PRK03545
344609004142	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609004143	putative substrate translocation pore; other site
344609004144	Transcriptional regulator [Transcription]; Region: LysR; COG0583
344609004145	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609004146	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
344609004147	putative dimerization interface [polypeptide binding]; other site
344609004148	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
344609004149	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
344609004150	NAD(P) binding site [chemical binding]; other site
344609004151	catalytic residues [active]
344609004152	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
344609004153	glutaminase; Provisional; Region: PRK00971
344609004154	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
344609004155	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
344609004156	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609004157	Transposase; Region: HTH_Tnp_1; pfam01527
344609004158	Predicted membrane protein [Function unknown]; Region: COG3781
344609004159	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
344609004160	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609004161	S-adenosylmethionine binding site [chemical binding]; other site
344609004162	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609004163	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609004164	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609004165	Domain of unknown function (DUF4376); Region: DUF4376; pfam14301
344609004166	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
344609004167	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
344609004168	Leucine-rich repeats, bacterial type; Region: LRR_BAC; smart00364
344609004169	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609004170	Transposase; Region: HTH_Tnp_1; pfam01527
344609004171	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004172	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
344609004173	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
344609004174	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
344609004175	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
344609004176	Transcriptional regulators [Transcription]; Region: GntR; COG1802
344609004177	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
344609004178	DNA-binding site [nucleotide binding]; DNA binding site
344609004179	FCD domain; Region: FCD; pfam07729
344609004180	malonic semialdehyde reductase; Provisional; Region: PRK10538
344609004181	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
344609004182	putative NAD(P) binding site [chemical binding]; other site
344609004183	homodimer interface [polypeptide binding]; other site
344609004184	homotetramer interface [polypeptide binding]; other site
344609004185	active site
344609004186	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
344609004187	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
344609004188	active site
344609004189	Zn binding site [ion binding]; other site
344609004190	hypothetical protein; Validated; Region: PRK03657
344609004191	hypothetical protein; Provisional; Region: PRK10053
344609004192	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004193	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
344609004194	metal binding site [ion binding]; metal-binding site
344609004195	active site
344609004196	I-site; other site
344609004197	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609004198	Transposase; Region: HTH_Tnp_1; pfam01527
344609004199	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004200	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004201	putative transposase OrfB; Reviewed; Region: PHA02517
344609004202	Integrase core domain; Region: rve; pfam00665
344609004203	Integrase core domain; Region: rve_3; pfam13683
344609004204	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609004205	Transposase; Region: HTH_Tnp_1; pfam01527
344609004206	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
344609004207	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
344609004208	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
344609004209	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
344609004210	Coenzyme A binding pocket [chemical binding]; other site
344609004211	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
344609004212	Prostaglandin dehydrogenases; Region: PGDH; cd05288
344609004213	NAD(P) binding site [chemical binding]; other site
344609004214	substrate binding site [chemical binding]; other site
344609004215	dimer interface [polypeptide binding]; other site
344609004216	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
344609004217	DNA-binding site [nucleotide binding]; DNA binding site
344609004218	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004219	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
344609004220	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
344609004221	N-terminal plug; other site
344609004222	ligand-binding site [chemical binding]; other site
344609004223	PQQ-like domain; Region: PQQ_2; pfam13360
344609004224	L-asparagine permease; Provisional; Region: PRK15049
344609004225	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
344609004226	C-terminal domain interface [polypeptide binding]; other site
344609004227	GSH binding site (G-site) [chemical binding]; other site
344609004228	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
344609004229	dimer interface [polypeptide binding]; other site
344609004230	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
344609004231	dimer interface [polypeptide binding]; other site
344609004232	substrate binding pocket (H-site) [chemical binding]; other site
344609004233	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004234	RHS protein; Region: RHS; pfam03527
344609004235	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609004236	HTH-like domain; Region: HTH_21; pfam13276
344609004237	Integrase core domain; Region: rve; pfam00665
344609004238	Integrase core domain; Region: rve_3; pfam13683
344609004239	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004240	aromatic amino acid exporter; Provisional; Region: PRK11689
344609004241	EamA-like transporter family; Region: EamA; pfam00892
344609004242	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
344609004243	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
344609004244	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
344609004245	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
344609004246	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
344609004247	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
344609004248	non-specific DNA binding site [nucleotide binding]; other site
344609004249	salt bridge; other site
344609004250	sequence-specific DNA binding site [nucleotide binding]; other site
344609004251	malate dehydrogenase; Provisional; Region: PRK13529
344609004252	Malic enzyme, N-terminal domain; Region: malic; pfam00390
344609004253	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
344609004254	NAD(P) binding site [chemical binding]; other site
344609004255	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
344609004256	Putative biofilm-dependent modulation protein; Region: BDM; cl11581
344609004257	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
344609004258	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
344609004259	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
344609004260	Walker A/P-loop; other site
344609004261	ATP binding site [chemical binding]; other site
344609004262	Q-loop/lid; other site
344609004263	ABC transporter signature motif; other site
344609004264	Walker B; other site
344609004265	D-loop; other site
344609004266	H-loop/switch region; other site
344609004267	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
344609004268	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
344609004269	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
344609004270	Walker A/P-loop; other site
344609004271	ATP binding site [chemical binding]; other site
344609004272	Q-loop/lid; other site
344609004273	ABC transporter signature motif; other site
344609004274	Walker B; other site
344609004275	D-loop; other site
344609004276	H-loop/switch region; other site
344609004277	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
344609004278	D-ala-D-ala transporter subunit; Provisional; Region: PRK09881
344609004279	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
344609004280	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609004281	dimer interface [polypeptide binding]; other site
344609004282	conserved gate region; other site
344609004283	putative PBP binding loops; other site
344609004284	ABC-ATPase subunit interface; other site
344609004285	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
344609004286	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
344609004287	D-alanyl-D-alanine dipeptidase; Provisional; Region: PRK10178
344609004288	cyclic-di-GMP phosphodiesterase; Provisional; Region: PRK11359
344609004289	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
344609004290	putative active site [active]
344609004291	heme pocket [chemical binding]; other site
344609004292	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
344609004293	putative active site [active]
344609004294	heme pocket [chemical binding]; other site
344609004295	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
344609004296	metal binding site [ion binding]; metal-binding site
344609004297	active site
344609004298	I-site; other site
344609004299	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
344609004300	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
344609004301	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
344609004302	glutamate:gamma-aminobutyrate antiporter; Region: 2A0307_GadC; TIGR00910
344609004303	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
344609004304	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609004305	catalytic residue [active]
344609004306	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
344609004307	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
344609004308	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
344609004309	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
344609004310	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
344609004311	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
344609004312	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
344609004313	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
344609004314	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
344609004315	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
344609004316	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
344609004317	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
344609004318	transcriptional regulator YdeO; Provisional; Region: PRK09940
344609004319	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609004320	putative oxidoreductase; Provisional; Region: PRK09939
344609004321	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
344609004322	putative molybdopterin cofactor binding site [chemical binding]; other site
344609004323	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
344609004324	putative molybdopterin cofactor binding site; other site
344609004325	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
344609004326	HipA-like C-terminal domain; Region: HipA_C; pfam07804
344609004327	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609004328	HTH-like domain; Region: HTH_21; pfam13276
344609004329	Integrase core domain; Region: rve; pfam00665
344609004330	Integrase core domain; Region: rve_3; pfam13683
344609004331	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609004332	Transposase; Region: HTH_Tnp_1; pfam01527
344609004333	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
344609004334	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
344609004335	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
344609004336	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
344609004337	putative [Fe4-S4] binding site [ion binding]; other site
344609004338	putative molybdopterin cofactor binding site [chemical binding]; other site
344609004339	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
344609004340	putative molybdopterin cofactor binding site; other site
344609004341	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
344609004342	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
344609004343	putative [Fe4-S4] binding site [ion binding]; other site
344609004344	putative molybdopterin cofactor binding site [chemical binding]; other site
344609004345	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
344609004346	molybdopterin cofactor binding site; other site
344609004347	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
344609004348	4Fe-4S binding domain; Region: Fer4; pfam00037
344609004349	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
344609004350	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
344609004351	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
344609004352	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
344609004353	Cl- selectivity filter; other site
344609004354	Cl- binding residues [ion binding]; other site
344609004355	pore gating glutamate residue; other site
344609004356	dimer interface [polypeptide binding]; other site
344609004357	putative dithiobiotin synthetase; Provisional; Region: PRK12374
344609004358	AAA domain; Region: AAA_26; pfam13500
344609004359	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
344609004360	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
344609004361	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
344609004362	nucleotide binding site [chemical binding]; other site
344609004363	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
344609004364	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609004365	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
344609004366	dimerization interface [polypeptide binding]; other site
344609004367	substrate binding pocket [chemical binding]; other site
344609004368	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
344609004369	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
344609004370	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
344609004371	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
344609004372	Domain of unknown function DUF20; Region: UPF0118; pfam01594
344609004373	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
344609004374	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
344609004375	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
344609004376	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
344609004377	ligand binding site [chemical binding]; other site
344609004378	homodimer interface [polypeptide binding]; other site
344609004379	NAD(P) binding site [chemical binding]; other site
344609004380	trimer interface B [polypeptide binding]; other site
344609004381	trimer interface A [polypeptide binding]; other site
344609004382	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
344609004383	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
344609004384	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
344609004385	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
344609004386	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
344609004387	Spore germination protein; Region: Spore_permease; cl17796
344609004388	dihydromonapterin reductase; Provisional; Region: PRK06483
344609004389	pteridine reductase (PR), classical (c) SDRs; Region: PR_SDR_c; cd05357
344609004390	NADP binding site [chemical binding]; other site
344609004391	substrate binding pocket [chemical binding]; other site
344609004392	active site
344609004393	GlpM protein; Region: GlpM; pfam06942
344609004394	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
344609004395	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609004396	active site
344609004397	phosphorylation site [posttranslational modification]
344609004398	intermolecular recognition site; other site
344609004399	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
344609004400	DNA binding site [nucleotide binding]
344609004401	sensor protein RstB; Provisional; Region: PRK10604
344609004402	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
344609004403	dimerization interface [polypeptide binding]; other site
344609004404	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609004405	dimer interface [polypeptide binding]; other site
344609004406	phosphorylation site [posttranslational modification]
344609004407	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609004408	ATP binding site [chemical binding]; other site
344609004409	Mg2+ binding site [ion binding]; other site
344609004410	G-X-G motif; other site
344609004411	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
344609004412	fumarate hydratase; Reviewed; Region: fumC; PRK00485
344609004413	Class II fumarases; Region: Fumarase_classII; cd01362
344609004414	active site
344609004415	tetramer interface [polypeptide binding]; other site
344609004416	fumarate hydratase; Provisional; Region: PRK15389
344609004417	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
344609004418	Fumarase C-terminus; Region: Fumerase_C; pfam05683
344609004419	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
344609004420	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
344609004421	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
344609004422	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
344609004423	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
344609004424	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004425	beta-D-glucuronidase; Provisional; Region: PRK10150
344609004426	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
344609004427	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
344609004428	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
344609004429	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
344609004430	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
344609004431	7-alpha-hydroxysteroid dehydrogenase; Validated; Region: PRK06113
344609004432	7 alpha-hydroxysteroid dehydrogenase (7 alpha-HSDH), classical (c) SDRs; Region: 7_alpha_HSDH_SDR_c; cd05365
344609004433	NAD binding site [chemical binding]; other site
344609004434	substrate binding site [chemical binding]; other site
344609004435	homotetramer interface [polypeptide binding]; other site
344609004436	homodimer interface [polypeptide binding]; other site
344609004437	active site
344609004438	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609004439	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609004440	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609004441	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
344609004442	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
344609004443	DNA binding site [nucleotide binding]
344609004444	domain linker motif; other site
344609004445	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
344609004446	putative dimerization interface [polypeptide binding]; other site
344609004447	putative ligand binding site [chemical binding]; other site
344609004448	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
344609004449	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
344609004450	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
344609004451	active site turn [active]
344609004452	phosphorylation site [posttranslational modification]
344609004453	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
344609004454	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
344609004455	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609004456	homodimer interface [polypeptide binding]; other site
344609004457	catalytic residue [active]
344609004458	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
344609004459	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
344609004460	active site
344609004461	purine riboside binding site [chemical binding]; other site
344609004462	putative oxidoreductase; Provisional; Region: PRK11579
344609004463	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
344609004464	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
344609004465	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
344609004466	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
344609004467	electron transport complex protein RsxA; Provisional; Region: PRK05151
344609004468	electron transport complex protein RnfB; Provisional; Region: PRK05113
344609004469	Putative Fe-S cluster; Region: FeS; pfam04060
344609004470	4Fe-4S binding domain; Region: Fer4; pfam00037
344609004471	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
344609004472	SLBB domain; Region: SLBB; pfam10531
344609004473	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
344609004474	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
344609004475	electron transport complex protein RnfG; Validated; Region: PRK01908
344609004476	electron transport complex RsxE subunit; Provisional; Region: PRK12405
344609004477	endonuclease III; Provisional; Region: PRK10702
344609004478	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
344609004479	minor groove reading motif; other site
344609004480	helix-hairpin-helix signature motif; other site
344609004481	substrate binding pocket [chemical binding]; other site
344609004482	active site
344609004483	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
344609004484	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
344609004485	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609004486	putative substrate translocation pore; other site
344609004487	POT family; Region: PTR2; pfam00854
344609004488	glutathionine S-transferase; Provisional; Region: PRK10542
344609004489	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
344609004490	C-terminal domain interface [polypeptide binding]; other site
344609004491	GSH binding site (G-site) [chemical binding]; other site
344609004492	dimer interface [polypeptide binding]; other site
344609004493	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
344609004494	N-terminal domain interface [polypeptide binding]; other site
344609004495	dimer interface [polypeptide binding]; other site
344609004496	substrate binding pocket (H-site) [chemical binding]; other site
344609004497	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004498	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
344609004499	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
344609004500	active site
344609004501	HIGH motif; other site
344609004502	dimer interface [polypeptide binding]; other site
344609004503	KMSKS motif; other site
344609004504	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
344609004505	RNA binding surface [nucleotide binding]; other site
344609004506	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
344609004507	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
344609004508	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
344609004509	lysozyme inhibitor; Provisional; Region: PRK11372
344609004510	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
344609004511	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
344609004512	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
344609004513	transcriptional regulator SlyA; Provisional; Region: PRK03573
344609004514	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
344609004515	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
344609004516	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
344609004517	HlyD family secretion protein; Region: HlyD_3; pfam13437
344609004518	Fusaric acid resistance protein family; Region: FUSC; pfam04632
344609004519	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
344609004520	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
344609004521	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
344609004522	E-class dimer interface [polypeptide binding]; other site
344609004523	P-class dimer interface [polypeptide binding]; other site
344609004524	active site
344609004525	Cu2+ binding site [ion binding]; other site
344609004526	Zn2+ binding site [ion binding]; other site
344609004527	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
344609004528	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
344609004529	active site
344609004530	catalytic tetrad [active]
344609004531	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
344609004532	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
344609004533	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
344609004534	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
344609004535	FMN binding site [chemical binding]; other site
344609004536	active site
344609004537	substrate binding site [chemical binding]; other site
344609004538	catalytic residue [active]
344609004539	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
344609004540	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
344609004541	dimer interface [polypeptide binding]; other site
344609004542	active site
344609004543	metal binding site [ion binding]; metal-binding site
344609004544	glutathione binding site [chemical binding]; other site
344609004545	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
344609004546	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
344609004547	dimer interface [polypeptide binding]; other site
344609004548	catalytic site [active]
344609004549	putative active site [active]
344609004550	putative substrate binding site [chemical binding]; other site
344609004551	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609004552	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609004553	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609004554	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609004555	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609004556	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609004557	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609004558	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609004559	putative ATP-dependent helicase Lhr; Provisional; Region: PRK09751
344609004560	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
344609004561	putative GSH binding site [chemical binding]; other site
344609004562	catalytic residues [active]
344609004563	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
344609004564	NlpC/P60 family; Region: NLPC_P60; pfam00877
344609004565	superoxide dismutase; Provisional; Region: PRK10543
344609004566	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
344609004567	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
344609004568	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609004569	Major Facilitator Superfamily; Region: MFS_1; pfam07690
344609004570	putative substrate translocation pore; other site
344609004571	hypothetical protein; Provisional; Region: PRK14756
344609004572	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
344609004573	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
344609004574	DNA binding site [nucleotide binding]
344609004575	domain linker motif; other site
344609004576	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
344609004577	dimerization interface [polypeptide binding]; other site
344609004578	ligand binding site [chemical binding]; other site
344609004579	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
344609004580	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609004581	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
344609004582	dimerization interface [polypeptide binding]; other site
344609004583	putative transporter; Provisional; Region: PRK11043
344609004584	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609004585	putative substrate translocation pore; other site
344609004586	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
344609004587	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
344609004588	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609004589	S-adenosylmethionine binding site [chemical binding]; other site
344609004590	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
344609004591	Lumazine binding domain; Region: Lum_binding; pfam00677
344609004592	Lumazine binding domain; Region: Lum_binding; pfam00677
344609004593	multidrug efflux protein; Reviewed; Region: PRK01766
344609004594	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
344609004595	cation binding site [ion binding]; other site
344609004596	hypothetical protein; Provisional; Region: PRK09945
344609004597	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
344609004598	putative monooxygenase; Provisional; Region: PRK11118
344609004599	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609004600	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609004601	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609004602	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609004603	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609004604	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609004605	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609004606	hypothetical protein; Provisional; Region: PRK09897
344609004607	hypothetical protein; Provisional; Region: PRK09946
344609004608	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
344609004609	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
344609004610	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
344609004611	hypothetical protein; Provisional; Region: PRK09947
344609004612	Aldehyde ferredoxin oxidoreductase, N-terminal domain; Region: AFOR_N; cl08354
344609004613	Aldehyde ferredoxin oxidoreductase, domains 2 & 3; Region: AFOR_C; pfam01314
344609004614	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004615	hypothetical protein; Provisional; Region: PRK10292
344609004616	pyruvate kinase; Provisional; Region: PRK09206
344609004617	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
344609004618	domain interfaces; other site
344609004619	active site
344609004620	murein lipoprotein; Provisional; Region: PRK15396
344609004621	cysteine desufuration protein SufE; Provisional; Region: PRK09296
344609004622	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
344609004623	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
344609004624	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
344609004625	catalytic residue [active]
344609004626	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
344609004627	FeS assembly protein SufD; Region: sufD; TIGR01981
344609004628	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
344609004629	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
344609004630	Walker A/P-loop; other site
344609004631	ATP binding site [chemical binding]; other site
344609004632	Q-loop/lid; other site
344609004633	ABC transporter signature motif; other site
344609004634	Walker B; other site
344609004635	D-loop; other site
344609004636	H-loop/switch region; other site
344609004637	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
344609004638	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
344609004639	CoenzymeA binding site [chemical binding]; other site
344609004640	subunit interaction site [polypeptide binding]; other site
344609004641	PHB binding site; other site
344609004642	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
344609004643	FAD binding domain; Region: FAD_binding_4; pfam01565
344609004644	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
344609004645	putative inner membrane protein; Provisional; Region: PRK10983
344609004646	Domain of unknown function DUF20; Region: UPF0118; pfam01594
344609004647	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004648	D-galactonate transporter; Region: 2A0114; TIGR00893
344609004649	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
344609004650	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
344609004651	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
344609004652	shikimate binding site; other site
344609004653	NAD(P) binding site [chemical binding]; other site
344609004654	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
344609004655	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
344609004656	active site
344609004657	catalytic residue [active]
344609004658	dimer interface [polypeptide binding]; other site
344609004659	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
344609004660	Coenzyme A transferase; Region: CoA_trans; smart00882
344609004661	Coenzyme A transferase; Region: CoA_trans; cl17247
344609004662	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
344609004663	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
344609004664	active site
344609004665	Cupin domain; Region: Cupin_2; pfam07883
344609004666	Winged helix DNA-binding domain (DUF1495); Region: DUF1495; cl01336
344609004667	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
344609004668	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609004669	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
344609004670	Ligand binding site [chemical binding]; other site
344609004671	Electron transfer flavoprotein domain; Region: ETF; pfam01012
344609004672	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
344609004673	Electron transfer flavoprotein domain; Region: ETF; smart00893
344609004674	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
344609004675	oxidoreductase; Provisional; Region: PRK10015
344609004676	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
344609004677	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
344609004678	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
344609004679	acyl-activating enzyme (AAE) consensus motif; other site
344609004680	putative AMP binding site [chemical binding]; other site
344609004681	putative active site [active]
344609004682	putative CoA binding site [chemical binding]; other site
344609004683	phosphoenolpyruvate synthase; Validated; Region: PRK06464
344609004684	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
344609004685	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
344609004686	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
344609004687	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609004688	HTH-like domain; Region: HTH_21; pfam13276
344609004689	Integrase core domain; Region: rve; pfam00665
344609004690	Integrase core domain; Region: rve_3; pfam13683
344609004691	PEP synthetase regulatory protein; Provisional; Region: PRK05339
344609004692	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
344609004693	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
344609004694	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
344609004695	Uncharacterized conserved protein [Function unknown]; Region: COG0397
344609004696	hypothetical protein; Validated; Region: PRK00029
344609004697	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
344609004698	NlpC/P60 family; Region: NLPC_P60; pfam00877
344609004699	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
344609004700	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
344609004701	Walker A/P-loop; other site
344609004702	ATP binding site [chemical binding]; other site
344609004703	Q-loop/lid; other site
344609004704	ABC transporter signature motif; other site
344609004705	Walker B; other site
344609004706	D-loop; other site
344609004707	H-loop/switch region; other site
344609004708	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
344609004709	catalytic residues [active]
344609004710	dimer interface [polypeptide binding]; other site
344609004711	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
344609004712	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
344609004713	ABC-ATPase subunit  interface; other site
344609004714	dimer interface [polypeptide binding]; other site
344609004715	putative PBP binding regions; other site
344609004716	integrase; Provisional; Region: int; PHA02601
344609004717	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
344609004718	active site
344609004719	DNA binding site [nucleotide binding]
344609004720	Int/Topo IB signature motif; other site
344609004721	Integrase core domain; Region: rve_3; pfam13683
344609004722	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609004723	Transposase; Region: HTH_Tnp_1; pfam01527
344609004724	Transposase; Region: HTH_Tnp_1; cl17663
344609004725	putative transposase OrfB; Reviewed; Region: PHA02517
344609004726	HTH-like domain; Region: HTH_21; pfam13276
344609004727	Integrase core domain; Region: rve; pfam00665
344609004728	Integrase core domain; Region: rve_3; pfam13683
344609004729	Integrase core domain; Region: rve; pfam00665
344609004730	Integrase core domain; Region: rve_3; pfam13683
344609004731	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
344609004732	nucleotide binding site [chemical binding]; other site
344609004733	Plasmid stability protein; Region: Plasmid_stab_B; pfam10784
344609004734	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
344609004735	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; cl15838
344609004736	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
344609004737	Protein of unknown function (DUF2570); Region: DUF2570; pfam10828
344609004738	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
344609004739	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
344609004740	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
344609004741	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
344609004742	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
344609004743	Phage tail protein (Tail_P2_I); Region: Tail_P2_I; pfam09684
344609004744	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
344609004745	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
344609004746	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
344609004747	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
344609004748	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004749	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
344609004750	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609004751	HTH-like domain; Region: HTH_21; pfam13276
344609004752	Integrase core domain; Region: rve; pfam00665
344609004753	Integrase core domain; Region: rve_3; pfam13683
344609004754	Hok/gef family; Region: HOK_GEF; pfam01848
344609004755	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609004756	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609004757	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
344609004758	IHF dimer interface [polypeptide binding]; other site
344609004759	IHF - DNA interface [nucleotide binding]; other site
344609004760	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
344609004761	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
344609004762	putative tRNA-binding site [nucleotide binding]; other site
344609004763	B3/4 domain; Region: B3_4; pfam03483
344609004764	tRNA synthetase B5 domain; Region: B5; smart00874
344609004765	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
344609004766	dimer interface [polypeptide binding]; other site
344609004767	motif 1; other site
344609004768	motif 3; other site
344609004769	motif 2; other site
344609004770	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
344609004771	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
344609004772	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
344609004773	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
344609004774	dimer interface [polypeptide binding]; other site
344609004775	motif 1; other site
344609004776	active site
344609004777	motif 2; other site
344609004778	motif 3; other site
344609004779	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
344609004780	23S rRNA binding site [nucleotide binding]; other site
344609004781	L21 binding site [polypeptide binding]; other site
344609004782	L13 binding site [polypeptide binding]; other site
344609004783	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
344609004784	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
344609004785	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
344609004786	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
344609004787	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
344609004788	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
344609004789	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
344609004790	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
344609004791	active site
344609004792	dimer interface [polypeptide binding]; other site
344609004793	motif 1; other site
344609004794	motif 2; other site
344609004795	motif 3; other site
344609004796	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
344609004797	anticodon binding site; other site
344609004798	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004799	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
344609004800	6-phosphofructokinase 2; Provisional; Region: PRK10294
344609004801	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
344609004802	putative substrate binding site [chemical binding]; other site
344609004803	putative ATP binding site [chemical binding]; other site
344609004804	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
344609004805	Phosphotransferase enzyme family; Region: APH; pfam01636
344609004806	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
344609004807	active site
344609004808	ATP binding site [chemical binding]; other site
344609004809	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
344609004810	YniB-like protein; Region: YniB; pfam14002
344609004811	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
344609004812	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
344609004813	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609004814	motif II; other site
344609004815	inner membrane protein; Provisional; Region: PRK11648
344609004816	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
344609004817	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
344609004818	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004819	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cl00166
344609004820	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; cl17295
344609004821	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004822	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
344609004823	active site
344609004824	P-loop; other site
344609004825	phosphorylation site [posttranslational modification]
344609004826	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
344609004827	NAD+ synthetase; Region: nadE; TIGR00552
344609004828	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
344609004829	homodimer interface [polypeptide binding]; other site
344609004830	NAD binding pocket [chemical binding]; other site
344609004831	ATP binding pocket [chemical binding]; other site
344609004832	Mg binding site [ion binding]; other site
344609004833	active-site loop [active]
344609004834	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
344609004835	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
344609004836	GIY-YIG motif/motif A; other site
344609004837	active site
344609004838	catalytic site [active]
344609004839	putative DNA binding site [nucleotide binding]; other site
344609004840	metal binding site [ion binding]; metal-binding site
344609004841	hypothetical protein; Provisional; Region: PRK11396
344609004842	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
344609004843	dimer interface [polypeptide binding]; other site
344609004844	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004845	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
344609004846	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
344609004847	putative active site [active]
344609004848	Zn binding site [ion binding]; other site
344609004849	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609004850	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609004851	succinylarginine dihydrolase; Provisional; Region: PRK13281
344609004852	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
344609004853	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
344609004854	NAD(P) binding site [chemical binding]; other site
344609004855	catalytic residues [active]
344609004856	arginine succinyltransferase; Provisional; Region: PRK10456
344609004857	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
344609004858	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
344609004859	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
344609004860	inhibitor-cofactor binding pocket; inhibition site
344609004861	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609004862	catalytic residue [active]
344609004863	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
344609004864	putative catalytic site [active]
344609004865	putative phosphate binding site [ion binding]; other site
344609004866	active site
344609004867	metal binding site A [ion binding]; metal-binding site
344609004868	DNA binding site [nucleotide binding]
344609004869	putative AP binding site [nucleotide binding]; other site
344609004870	putative metal binding site B [ion binding]; other site
344609004871	Uncharacterized conserved protein [Function unknown]; Region: COG0398
344609004872	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
344609004873	Uncharacterized conserved protein [Function unknown]; Region: COG0398
344609004874	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
344609004875	Uncharacterized conserved protein [Function unknown]; Region: COG2128
344609004876	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
344609004877	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
344609004878	hypothetical protein; Provisional; Region: PRK11622
344609004879	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4135
344609004880	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609004881	dimer interface [polypeptide binding]; other site
344609004882	conserved gate region; other site
344609004883	putative PBP binding loops; other site
344609004884	ABC-ATPase subunit interface; other site
344609004885	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
344609004886	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609004887	Walker A/P-loop; other site
344609004888	ATP binding site [chemical binding]; other site
344609004889	Q-loop/lid; other site
344609004890	ABC transporter signature motif; other site
344609004891	Walker B; other site
344609004892	D-loop; other site
344609004893	H-loop/switch region; other site
344609004894	Rhodanese Homology Domain; Region: RHOD; smart00450
344609004895	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
344609004896	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
344609004897	active site residue [active]
344609004898	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
344609004899	active site residue [active]
344609004900	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
344609004901	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004902	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
344609004903	glutamate dehydrogenase; Provisional; Region: PRK09414
344609004904	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
344609004905	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
344609004906	NAD(P) binding site [chemical binding]; other site
344609004907	Protein of unknown function (DUF1266); Region: DUF1266; cl14673
344609004908	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004909	DNA topoisomerase III; Provisional; Region: PRK07726
344609004910	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
344609004911	active site
344609004912	putative interdomain interaction site [polypeptide binding]; other site
344609004913	putative metal-binding site [ion binding]; other site
344609004914	putative nucleotide binding site [chemical binding]; other site
344609004915	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
344609004916	domain I; other site
344609004917	DNA binding groove [nucleotide binding]
344609004918	phosphate binding site [ion binding]; other site
344609004919	domain II; other site
344609004920	domain III; other site
344609004921	nucleotide binding site [chemical binding]; other site
344609004922	catalytic site [active]
344609004923	domain IV; other site
344609004924	selenophosphate synthetase; Provisional; Region: PRK00943
344609004925	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
344609004926	dimerization interface [polypeptide binding]; other site
344609004927	putative ATP binding site [chemical binding]; other site
344609004928	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
344609004929	putative FMN binding site [chemical binding]; other site
344609004930	protease 4; Provisional; Region: PRK10949
344609004931	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
344609004932	tandem repeat interface [polypeptide binding]; other site
344609004933	oligomer interface [polypeptide binding]; other site
344609004934	active site residues [active]
344609004935	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
344609004936	tandem repeat interface [polypeptide binding]; other site
344609004937	oligomer interface [polypeptide binding]; other site
344609004938	active site residues [active]
344609004939	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
344609004940	active site
344609004941	homodimer interface [polypeptide binding]; other site
344609004942	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
344609004943	Isochorismatase family; Region: Isochorismatase; pfam00857
344609004944	catalytic triad [active]
344609004945	metal binding site [ion binding]; metal-binding site
344609004946	conserved cis-peptide bond; other site
344609004947	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
344609004948	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
344609004949	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
344609004950	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
344609004951	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609004952	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609004953	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609004954	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
344609004955	active site
344609004956	phosphate binding residues; other site
344609004957	catalytic residues [active]
344609004958	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
344609004959	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
344609004960	active site
344609004961	catalytic tetrad [active]
344609004962	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
344609004963	hypothetical protein; Provisional; Region: PRK05325
344609004964	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
344609004965	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
344609004966	metal binding site [ion binding]; metal-binding site
344609004967	active site
344609004968	I-site; other site
344609004969	putative transposase OrfB; Reviewed; Region: PHA02517
344609004970	Integrase core domain; Region: rve; pfam00665
344609004971	Integrase core domain; Region: rve_3; pfam13683
344609004972	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
344609004973	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
344609004974	metal binding site [ion binding]; metal-binding site
344609004975	active site
344609004976	I-site; other site
344609004977	putative transposase OrfB; Reviewed; Region: PHA02517
344609004978	Integrase core domain; Region: rve; pfam00665
344609004979	Integrase core domain; Region: rve_3; pfam13683
344609004980	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
344609004981	putative deacylase active site [active]
344609004982	Predicted membrane protein [Function unknown]; Region: COG2707
344609004983	cyanate transporter; Region: CynX; TIGR00896
344609004984	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609004985	Uncharacterized conserved protein [Function unknown]; Region: COG3189
344609004986	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
344609004987	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
344609004988	Domain of unknown function (DUF333); Region: DUF333; pfam03891
344609004989	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004990	hypothetical protein; Provisional; Region: PRK10457
344609004991	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
344609004992	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004993	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609004994	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609004995	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609004996	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
344609004997	tartrate dehydrogenase; Region: TTC; TIGR02089
344609004998	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609004999	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
344609005000	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
344609005001	[2Fe-2S] cluster binding site [ion binding]; other site
344609005002	C-terminal catalytic domain of the oxygenase alpha subunit of an uncharacterized subgroup of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C_2; cd08886
344609005003	putative alpha subunit interface [polypeptide binding]; other site
344609005004	putative active site [active]
344609005005	putative substrate binding site [chemical binding]; other site
344609005006	Fe binding site [ion binding]; other site
344609005007	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
344609005008	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
344609005009	FMN-binding pocket [chemical binding]; other site
344609005010	flavin binding motif; other site
344609005011	phosphate binding motif [ion binding]; other site
344609005012	beta-alpha-beta structure motif; other site
344609005013	NAD binding pocket [chemical binding]; other site
344609005014	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
344609005015	catalytic loop [active]
344609005016	iron binding site [ion binding]; other site
344609005017	ribonuclease D; Provisional; Region: PRK10829
344609005018	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
344609005019	catalytic site [active]
344609005020	putative active site [active]
344609005021	putative substrate binding site [chemical binding]; other site
344609005022	Helicase and RNase D C-terminal; Region: HRDC; smart00341
344609005023	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
344609005024	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
344609005025	acyl-activating enzyme (AAE) consensus motif; other site
344609005026	putative AMP binding site [chemical binding]; other site
344609005027	putative active site [active]
344609005028	putative CoA binding site [chemical binding]; other site
344609005029	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
344609005030	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
344609005031	Glycoprotease family; Region: Peptidase_M22; pfam00814
344609005032	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
344609005033	DEAD/DEAH box helicase; Region: DEAD; pfam00270
344609005034	DEAD_2; Region: DEAD_2; pfam06733
344609005035	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
344609005036	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
344609005037	homotrimer interaction site [polypeptide binding]; other site
344609005038	putative active site [active]
344609005039	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609005040	hypothetical protein; Provisional; Region: PRK05114
344609005041	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
344609005042	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
344609005043	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
344609005044	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
344609005045	putative active site [active]
344609005046	putative CoA binding site [chemical binding]; other site
344609005047	nudix motif; other site
344609005048	metal binding site [ion binding]; metal-binding site
344609005049	L-serine deaminase; Provisional; Region: PRK15023
344609005050	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
344609005051	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
344609005052	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
344609005053	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609005054	Transposase; Region: HTH_Tnp_1; pfam01527
344609005055	putative transposase OrfB; Reviewed; Region: PHA02517
344609005056	Integrase core domain; Region: rve; pfam00665
344609005057	Integrase core domain; Region: rve_3; pfam13683
344609005058	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609005059	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609005060	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609005061	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
344609005062	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
344609005063	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
344609005064	Transporter associated domain; Region: CorC_HlyC; smart01091
344609005065	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
344609005066	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
344609005067	active pocket/dimerization site; other site
344609005068	active site
344609005069	phosphorylation site [posttranslational modification]
344609005070	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
344609005071	active site
344609005072	phosphorylation site [posttranslational modification]
344609005073	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
344609005074	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
344609005075	Predicted membrane protein [Function unknown]; Region: COG4811
344609005076	yybP-ykoY leader
344609005077	hypothetical protein; Provisional; Region: PRK11469
344609005078	Domain of unknown function DUF; Region: DUF204; pfam02659
344609005079	Domain of unknown function DUF; Region: DUF204; pfam02659
344609005080	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
344609005081	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609005082	S-adenosylmethionine binding site [chemical binding]; other site
344609005083	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
344609005084	DNA-binding site [nucleotide binding]; DNA binding site
344609005085	RNA-binding motif; other site
344609005086	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609005087	YebO-like protein; Region: YebO; pfam13974
344609005088	PhoPQ regulatory protein; Provisional; Region: PRK10299
344609005089	YobH-like protein; Region: YobH; pfam13996
344609005090	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
344609005091	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
344609005092	dimerization interface [polypeptide binding]; other site
344609005093	putative Zn2+ binding site [ion binding]; other site
344609005094	putative DNA binding site [nucleotide binding]; other site
344609005095	Bacterial transcriptional regulator; Region: IclR; pfam01614
344609005096	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609005097	Major Facilitator Superfamily; Region: MFS_1; pfam07690
344609005098	putative substrate translocation pore; other site
344609005099	Predicted integral membrane protein [Function unknown]; Region: COG5521
344609005100	heat shock protein HtpX; Provisional; Region: PRK05457
344609005101	carboxy-terminal protease; Provisional; Region: PRK11186
344609005102	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
344609005103	protein binding site [polypeptide binding]; other site
344609005104	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
344609005105	Catalytic dyad [active]
344609005106	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
344609005107	ProP expression regulator; Provisional; Region: PRK04950
344609005108	ProQ/FINO family; Region: ProQ; pfam04352
344609005109	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
344609005110	GAF domain; Region: GAF_2; pfam13185
344609005111	integral membrane protein, PqiA family; Region: pqiA_fam; TIGR00155
344609005112	Paraquat-inducible protein A; Region: PqiA; pfam04403
344609005113	Paraquat-inducible protein A; Region: PqiA; pfam04403
344609005114	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
344609005115	mce related protein; Region: MCE; pfam02470
344609005116	mce related protein; Region: MCE; pfam02470
344609005117	mce related protein; Region: MCE; pfam02470
344609005118	mce related protein; Region: MCE; pfam02470
344609005119	mce related protein; Region: MCE; pfam02470
344609005120	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
344609005121	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609005122	S-adenosylmethionine binding site [chemical binding]; other site
344609005123	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
344609005124	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
344609005125	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
344609005126	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609005127	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609005128	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609005129	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609005130	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609005131	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609005132	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609005133	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
344609005134	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
344609005135	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
344609005136	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
344609005137	putative transposase OrfB; Reviewed; Region: PHA02517
344609005138	Integrase core domain; Region: rve; pfam00665
344609005139	Integrase core domain; Region: rve_3; pfam13683
344609005140	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609005141	Transposase; Region: HTH_Tnp_1; pfam01527
344609005142	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
344609005143	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
344609005144	hypothetical protein; Provisional; Region: PRK10301
344609005145	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
344609005146	Predicted amidohydrolase [General function prediction only]; Region: COG0388
344609005147	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
344609005148	exodeoxyribonuclease X; Provisional; Region: PRK07983
344609005149	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
344609005150	active site
344609005151	catalytic site [active]
344609005152	substrate binding site [chemical binding]; other site
344609005153	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
344609005154	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
344609005155	putative metal binding site [ion binding]; other site
344609005156	hypothetical protein; Provisional; Region: PRK13680
344609005157	YebG protein; Region: YebG; cl01217
344609005158	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
344609005159	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
344609005160	ATP-grasp domain; Region: ATP-grasp; pfam02222
344609005161	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
344609005162	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
344609005163	active site
344609005164	intersubunit interface [polypeptide binding]; other site
344609005165	catalytic residue [active]
344609005166	phosphogluconate dehydratase; Validated; Region: PRK09054
344609005167	6-phosphogluconate dehydratase; Region: edd; TIGR01196
344609005168	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
344609005169	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
344609005170	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
344609005171	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
344609005172	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
344609005173	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
344609005174	putative active site [active]
344609005175	pyruvate kinase; Provisional; Region: PRK05826
344609005176	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
344609005177	domain interfaces; other site
344609005178	active site
344609005179	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609005180	HTH-like domain; Region: HTH_21; pfam13276
344609005181	Integrase core domain; Region: rve; pfam00665
344609005182	Integrase core domain; Region: rve_3; pfam13683
344609005183	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609005184	dimer interface [polypeptide binding]; other site
344609005185	conserved gate region; other site
344609005186	putative PBP binding loops; other site
344609005187	ABC-ATPase subunit interface; other site
344609005188	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
344609005189	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
344609005190	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
344609005191	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
344609005192	trimer interface [polypeptide binding]; other site
344609005193	active site
344609005194	UDP-GlcNAc binding site [chemical binding]; other site
344609005195	lipid binding site [chemical binding]; lipid-binding site
344609005196	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609005197	Walker A/P-loop; other site
344609005198	ATP binding site [chemical binding]; other site
344609005199	Q-loop/lid; other site
344609005200	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609005201	Transposase; Region: HTH_Tnp_1; pfam01527
344609005202	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609005203	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609005204	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609005205	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609005206	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609005207	putative transposase OrfB; Reviewed; Region: PHA02517
344609005208	Integrase core domain; Region: rve; pfam00665
344609005209	Integrase core domain; Region: rve_3; pfam13683
344609005210	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609005211	HTH-like domain; Region: HTH_21; pfam13276
344609005212	Integrase core domain; Region: rve; pfam00665
344609005213	Integrase core domain; Region: rve_3; pfam13683
344609005214	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609005215	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
344609005216	DNA methylase; Region: N6_N4_Mtase; pfam01555
344609005217	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
344609005218	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
344609005219	Protein of unknown function (DUF968); Region: DUF968; pfam06147
344609005220	KilA-N domain; Region: KilA-N; pfam04383
344609005221	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
344609005222	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; pfam05869
344609005223	Helix-turn-helix domain; Region: HTH_36; pfam13730
344609005224	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609005225	Transposase; Region: HTH_Tnp_1; pfam01527
344609005226	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609005227	S-adenosylmethionine binding site [chemical binding]; other site
344609005228	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609005229	S-adenosylmethionine binding site [chemical binding]; other site
344609005230	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
344609005231	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
344609005232	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
344609005233	molybdopterin cofactor binding site [chemical binding]; other site
344609005234	substrate binding site [chemical binding]; other site
344609005235	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
344609005236	molybdopterin cofactor binding site; other site
344609005237	trimethylamine-N-oxide reductase c-type cytochrome TorC; Region: torC; TIGR02162
344609005238	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
344609005239	copper homeostasis protein CutC; Provisional; Region: PRK11572
344609005240	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
344609005241	putative metal binding site [ion binding]; other site
344609005242	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
344609005243	arginyl-tRNA synthetase; Region: argS; TIGR00456
344609005244	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
344609005245	active site
344609005246	HIGH motif; other site
344609005247	KMSK motif region; other site
344609005248	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
344609005249	tRNA binding surface [nucleotide binding]; other site
344609005250	anticodon binding site; other site
344609005251	Flagellar protein FlhE; Region: FlhE; pfam06366
344609005252	chemotaxis regulator CheZ; Provisional; Region: PRK11166
344609005253	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
344609005254	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609005255	active site
344609005256	phosphorylation site [posttranslational modification]
344609005257	intermolecular recognition site; other site
344609005258	dimerization interface [polypeptide binding]; other site
344609005259	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
344609005260	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609005261	active site
344609005262	phosphorylation site [posttranslational modification]
344609005263	intermolecular recognition site; other site
344609005264	dimerization interface [polypeptide binding]; other site
344609005265	CheB methylesterase; Region: CheB_methylest; pfam01339
344609005266	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
344609005267	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
344609005268	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609005269	S-adenosylmethionine binding site [chemical binding]; other site
344609005270	methyl-accepting protein IV; Provisional; Region: PRK09793
344609005271	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
344609005272	dimer interface [polypeptide binding]; other site
344609005273	ligand binding site [chemical binding]; other site
344609005274	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
344609005275	dimerization interface [polypeptide binding]; other site
344609005276	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
344609005277	dimer interface [polypeptide binding]; other site
344609005278	putative CheW interface [polypeptide binding]; other site
344609005279	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
344609005280	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
344609005281	dimer interface [polypeptide binding]; other site
344609005282	ligand binding site [chemical binding]; other site
344609005283	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
344609005284	dimer interface [polypeptide binding]; other site
344609005285	putative CheW interface [polypeptide binding]; other site
344609005286	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
344609005287	putative CheA interaction surface; other site
344609005288	chemotaxis protein CheA; Provisional; Region: PRK10547
344609005289	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
344609005290	putative binding surface; other site
344609005291	active site
344609005292	CheY binding; Region: CheY-binding; pfam09078
344609005293	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
344609005294	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609005295	ATP binding site [chemical binding]; other site
344609005296	Mg2+ binding site [ion binding]; other site
344609005297	G-X-G motif; other site
344609005298	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
344609005299	putative transposase OrfB; Reviewed; Region: PHA02517
344609005300	Integrase core domain; Region: rve; pfam00665
344609005301	Integrase core domain; Region: rve_3; pfam13683
344609005302	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609005303	Transposase; Region: HTH_Tnp_1; pfam01527
344609005304	Prophage antirepressor [Transcription]; Region: COG3617
344609005305	BRO family, N-terminal domain; Region: Bro-N; smart01040
344609005306	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
344609005307	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609005308	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609005309	Transposase; Region: HTH_Tnp_1; pfam01527
344609005310	putative transposase OrfB; Reviewed; Region: PHA02517
344609005311	Integrase core domain; Region: rve; pfam00665
344609005312	Integrase core domain; Region: rve_3; pfam13683
344609005313	Domain of unknown function (DUF1737); Region: DUF1737; pfam08410
344609005314	Domain of unknown function (DUF303); Region: DUF303; pfam03629
344609005315	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
344609005316	DNA methylase; Region: N6_N4_Mtase; pfam01555
344609005317	DNA methylase; Region: N6_N4_Mtase; pfam01555
344609005318	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
344609005319	IS2 repressor TnpA; Reviewed; Region: PRK09413
344609005320	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609005321	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609005322	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
344609005323	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609005324	dimer interface [polypeptide binding]; other site
344609005325	conserved gate region; other site
344609005326	putative PBP binding loops; other site
344609005327	ABC-ATPase subunit interface; other site
344609005328	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
344609005329	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
344609005330	NAD-dependent deacetylase; Provisional; Region: PRK00481
344609005331	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
344609005332	NAD+ binding site [chemical binding]; other site
344609005333	substrate binding site [chemical binding]; other site
344609005334	Zn binding site [ion binding]; other site
344609005335	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
344609005336	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
344609005337	FtsX-like permease family; Region: FtsX; pfam02687
344609005338	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
344609005339	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
344609005340	Walker A/P-loop; other site
344609005341	ATP binding site [chemical binding]; other site
344609005342	Q-loop/lid; other site
344609005343	ABC transporter signature motif; other site
344609005344	Walker B; other site
344609005345	D-loop; other site
344609005346	H-loop/switch region; other site
344609005347	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
344609005348	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
344609005349	FtsX-like permease family; Region: FtsX; pfam02687
344609005350	Predicted membrane protein [Function unknown]; Region: COG4763
344609005351	Acyltransferase family; Region: Acyl_transf_3; pfam01757
344609005352	transcription-repair coupling factor; Provisional; Region: PRK10689
344609005353	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
344609005354	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
344609005355	ATP binding site [chemical binding]; other site
344609005356	putative Mg++ binding site [ion binding]; other site
344609005357	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
344609005358	nucleotide binding region [chemical binding]; other site
344609005359	ATP-binding site [chemical binding]; other site
344609005360	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
344609005361	L,D-transpeptidase; Provisional; Region: PRK10260
344609005362	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
344609005363	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
344609005364	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
344609005365	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
344609005366	hypothetical protein; Provisional; Region: PRK11280
344609005367	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
344609005368	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
344609005369	hypothetical protein; Provisional; Region: PRK04940
344609005370	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
344609005371	beta-hexosaminidase; Provisional; Region: PRK05337
344609005372	thiamine kinase; Region: ycfN_thiK; TIGR02721
344609005373	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
344609005374	active site
344609005375	substrate binding site [chemical binding]; other site
344609005376	ATP binding site [chemical binding]; other site
344609005377	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
344609005378	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
344609005379	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
344609005380	putative dimer interface [polypeptide binding]; other site
344609005381	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
344609005382	nucleotide binding site/active site [active]
344609005383	HIT family signature motif; other site
344609005384	catalytic residue [active]
344609005385	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
344609005386	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
344609005387	N-terminal plug; other site
344609005388	ligand-binding site [chemical binding]; other site
344609005389	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
344609005390	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
344609005391	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
344609005392	active site turn [active]
344609005393	phosphorylation site [posttranslational modification]
344609005394	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
344609005395	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
344609005396	active site
344609005397	DNA polymerase III subunit delta'; Validated; Region: PRK07993
344609005398	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
344609005399	thymidylate kinase; Validated; Region: tmk; PRK00698
344609005400	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
344609005401	TMP-binding site; other site
344609005402	ATP-binding site [chemical binding]; other site
344609005403	conserved hypothetical protein, YceG family; Region: TIGR00247
344609005404	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
344609005405	dimerization interface [polypeptide binding]; other site
344609005406	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
344609005407	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
344609005408	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609005409	catalytic residue [active]
344609005410	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
344609005411	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
344609005412	dimer interface [polypeptide binding]; other site
344609005413	active site
344609005414	acyl carrier protein; Provisional; Region: acpP; PRK00982
344609005415	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
344609005416	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
344609005417	NAD(P) binding site [chemical binding]; other site
344609005418	homotetramer interface [polypeptide binding]; other site
344609005419	homodimer interface [polypeptide binding]; other site
344609005420	active site
344609005421	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
344609005422	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
344609005423	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
344609005424	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
344609005425	dimer interface [polypeptide binding]; other site
344609005426	active site
344609005427	CoA binding pocket [chemical binding]; other site
344609005428	putative phosphate acyltransferase; Provisional; Region: PRK05331
344609005429	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
344609005430	hypothetical protein; Provisional; Region: PRK11193
344609005431	Maf-like protein; Region: Maf; pfam02545
344609005432	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
344609005433	active site
344609005434	dimer interface [polypeptide binding]; other site
344609005435	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
344609005436	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
344609005437	RNA binding surface [nucleotide binding]; other site
344609005438	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
344609005439	active site
344609005440	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609005441	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609005442	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609005443	RNase E 5' UTR element
344609005444	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
344609005445	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
344609005446	homodimer interface [polypeptide binding]; other site
344609005447	oligonucleotide binding site [chemical binding]; other site
344609005448	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
344609005449	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
344609005450	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
344609005451	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
344609005452	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
344609005453	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
344609005454	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
344609005455	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
344609005456	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
344609005457	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
344609005458	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
344609005459	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
344609005460	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
344609005461	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
344609005462	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
344609005463	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
344609005464	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
344609005465	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
344609005466	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
344609005467	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
344609005468	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
344609005469	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
344609005470	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
344609005471	Flagellar basal body P-ring biosynthesis protein [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FlgA; COG1261
344609005472	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
344609005473	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
344609005474	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
344609005475	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
344609005476	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
344609005477	MviN-like protein; Region: MVIN; pfam03023
344609005478	hypothetical protein; Provisional; Region: PRK11239
344609005479	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
344609005480	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
344609005481	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
344609005482	multidrug resistance protein MdtH; Provisional; Region: PRK11646
344609005483	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609005484	putative substrate translocation pore; other site
344609005485	glutaredoxin 2; Provisional; Region: PRK10387
344609005486	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
344609005487	C-terminal domain interface [polypeptide binding]; other site
344609005488	GSH binding site (G-site) [chemical binding]; other site
344609005489	catalytic residues [active]
344609005490	putative dimer interface [polypeptide binding]; other site
344609005491	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
344609005492	N-terminal domain interface [polypeptide binding]; other site
344609005493	lipoprotein; Provisional; Region: PRK10598
344609005494	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
344609005495	active site
344609005496	substrate binding pocket [chemical binding]; other site
344609005497	dimer interface [polypeptide binding]; other site
344609005498	DNA damage-inducible protein I; Provisional; Region: PRK10597
344609005499	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
344609005500	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
344609005501	hydroxyglutarate oxidase; Provisional; Region: PRK11728
344609005502	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
344609005503	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
344609005504	hypothetical protein; Provisional; Region: PRK03757
344609005505	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609005506	Transposase; Region: HTH_Tnp_1; pfam01527
344609005507	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
344609005508	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
344609005509	putative acyl-acceptor binding pocket; other site
344609005510	secY/secA suppressor protein; Provisional; Region: PRK11467
344609005511	lipoprotein; Provisional; Region: PRK10175
344609005512	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609005513	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609005514	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609005515	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
344609005516	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
344609005517	Ligand binding site; other site
344609005518	DXD motif; other site
344609005519	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
344609005520	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
344609005521	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
344609005522	Acyltransferase family; Region: Acyl_transf_3; pfam01757
344609005523	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
344609005524	PLD-like domain; Region: PLDc_2; pfam13091
344609005525	putative active site [active]
344609005526	catalytic site [active]
344609005527	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
344609005528	PLD-like domain; Region: PLDc_2; pfam13091
344609005529	putative active site [active]
344609005530	catalytic site [active]
344609005531	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
344609005532	putative ADP-ribose binding site [chemical binding]; other site
344609005533	putative active site [active]
344609005534	Fimbrial protein; Region: Fimbrial; cl01416
344609005535	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609005536	Curli assembly protein CsgE; Region: CsgE; cl08115
344609005537	curli assembly protein CsgF; Provisional; Region: PRK10050
344609005538	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
344609005539	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
344609005540	putative hydrolase; Validated; Region: PRK09248
344609005541	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
344609005542	active site
344609005543	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
344609005544	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
344609005545	putative ligand binding site [chemical binding]; other site
344609005546	NAD binding site [chemical binding]; other site
344609005547	dimerization interface [polypeptide binding]; other site
344609005548	catalytic site [active]
344609005549	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
344609005550	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609005551	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
344609005552	hypothetical protein; Provisional; Region: PRK10536
344609005553	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
344609005554	Na binding site [ion binding]; other site
344609005555	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
344609005556	Predicted transcriptional regulator [Transcription]; Region: COG3905
344609005557	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
344609005558	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
344609005559	Glutamate binding site [chemical binding]; other site
344609005560	NAD binding site [chemical binding]; other site
344609005561	catalytic residues [active]
344609005562	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
344609005563	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
344609005564	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
344609005565	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
344609005566	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609005567	Transposase; Region: HTH_Tnp_1; pfam01527
344609005568	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
344609005569	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609005570	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
344609005571	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
344609005572	HSP70 interaction site [polypeptide binding]; other site
344609005573	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
344609005574	substrate binding site [polypeptide binding]; other site
344609005575	dimer interface [polypeptide binding]; other site
344609005576	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
344609005577	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
344609005578	chaperone protein TorD; Validated; Region: torD; PRK04976
344609005579	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
344609005580	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609005581	active site
344609005582	phosphorylation site [posttranslational modification]
344609005583	intermolecular recognition site; other site
344609005584	dimerization interface [polypeptide binding]; other site
344609005585	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
344609005586	DNA binding site [nucleotide binding]
344609005587	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
344609005588	HAMP domain; Region: HAMP; pfam00672
344609005589	dimerization interface [polypeptide binding]; other site
344609005590	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609005591	dimer interface [polypeptide binding]; other site
344609005592	phosphorylation site [posttranslational modification]
344609005593	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609005594	ATP binding site [chemical binding]; other site
344609005595	Mg2+ binding site [ion binding]; other site
344609005596	G-X-G motif; other site
344609005597	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609005598	active site
344609005599	phosphorylation site [posttranslational modification]
344609005600	intermolecular recognition site; other site
344609005601	dimerization interface [polypeptide binding]; other site
344609005602	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
344609005603	putative binding surface; other site
344609005604	active site
344609005605	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
344609005606	4Fe-4S binding domain; Region: Fer4_5; pfam12801
344609005607	4Fe-4S binding domain; Region: Fer4_5; pfam12801
344609005608	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
344609005609	GnsA/GnsB family; Region: GnsAB; pfam08178
344609005610	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609005611	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609005612	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609005613	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
344609005614	DNA-binding site [nucleotide binding]; DNA binding site
344609005615	RNA-binding motif; other site
344609005616	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
344609005617	DNA-binding site [nucleotide binding]; DNA binding site
344609005618	RNA-binding motif; other site
344609005619	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
344609005620	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
344609005621	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
344609005622	polysaccharide export protein Wza; Provisional; Region: PRK15078
344609005623	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
344609005624	SLBB domain; Region: SLBB; pfam10531
344609005625	SLBB domain; Region: SLBB; pfam10531
344609005626	Low molecular weight phosphatase family; Region: LMWPc; cd00115
344609005627	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
344609005628	active site
344609005629	cryptic autophosphorylating protein tyrosine kinase Etk; Provisional; Region: PRK09841
344609005630	Chain length determinant protein; Region: Wzz; pfam02706
344609005631	Chain length determinant protein; Region: Wzz; cl15801
344609005632	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
344609005633	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
344609005634	Nucleotide binding site [chemical binding]; other site
344609005635	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
344609005636	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
344609005637	catalytic core [active]
344609005638	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
344609005639	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
344609005640	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
344609005641	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
344609005642	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
344609005643	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
344609005644	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
344609005645	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
344609005646	putative substrate-binding site; other site
344609005647	nickel binding site [ion binding]; other site
344609005648	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
344609005649	hydrogenase 1 large subunit; Provisional; Region: PRK10170
344609005650	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
344609005651	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
344609005652	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
344609005653	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
344609005654	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
344609005655	YccA-like proteins; Region: YccA_like; cd10433
344609005656	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
344609005657	sulfur transfer protein TusE; Provisional; Region: PRK11508
344609005658	Acylphosphatase; Region: Acylphosphatase; cl00551
344609005659	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
344609005660	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
344609005661	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
344609005662	putative RNA binding site [nucleotide binding]; other site
344609005663	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609005664	S-adenosylmethionine binding site [chemical binding]; other site
344609005665	heat shock protein HspQ; Provisional; Region: PRK14129
344609005666	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
344609005667	hypothetical protein; Provisional; Region: PRK03641
344609005668	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
344609005669	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
344609005670	active site
344609005671	dimer interfaces [polypeptide binding]; other site
344609005672	catalytic residues [active]
344609005673	DNA helicase IV; Provisional; Region: helD; PRK11054
344609005674	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
344609005675	Part of AAA domain; Region: AAA_19; pfam13245
344609005676	Family description; Region: UvrD_C_2; pfam13538
344609005677	Predicted membrane protein [Function unknown]; Region: COG3304
344609005678	Domain of unknown function (DUF307); Region: DUF307; pfam03733
344609005679	Domain of unknown function (DUF307); Region: DUF307; pfam03733
344609005680	TIGR01666 family membrane protein; Region: YCCS
344609005681	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
344609005682	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
344609005683	TfoX C-terminal domain; Region: TfoX_C; pfam04994
344609005684	cell division inhibitor SulA; Region: sula; TIGR00623
344609005685	outer membrane protein A; Reviewed; Region: PRK10808
344609005686	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
344609005687	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
344609005688	ligand binding site [chemical binding]; other site
344609005689	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
344609005690	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
344609005691	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
344609005692	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
344609005693	active site 1 [active]
344609005694	dimer interface [polypeptide binding]; other site
344609005695	active site 2 [active]
344609005696	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609005697	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609005698	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609005699	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609005700	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609005701	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609005702	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609005703	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
344609005704	Protein of unknown function (DUF330); Region: DUF330; pfam03886
344609005705	paraquat-inducible protein B; Provisional; Region: PRK10807
344609005706	mce related protein; Region: MCE; pfam02470
344609005707	mce related protein; Region: MCE; pfam02470
344609005708	mce related protein; Region: MCE; pfam02470
344609005709	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
344609005710	Paraquat-inducible protein A; Region: PqiA; pfam04403
344609005711	Paraquat-inducible protein A; Region: PqiA; pfam04403
344609005712	ABC transporter ATPase component; Reviewed; Region: PRK11147
344609005713	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609005714	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609005715	Walker A/P-loop; other site
344609005716	Walker A/P-loop; other site
344609005717	ATP binding site [chemical binding]; other site
344609005718	ATP binding site [chemical binding]; other site
344609005719	Q-loop/lid; other site
344609005720	Q-loop/lid; other site
344609005721	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
344609005722	ABC transporter signature motif; other site
344609005723	Walker B; other site
344609005724	D-loop; other site
344609005725	ABC transporter; Region: ABC_tran_2; pfam12848
344609005726	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
344609005727	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
344609005728	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
344609005729	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
344609005730	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609005731	S-adenosylmethionine binding site [chemical binding]; other site
344609005732	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
344609005733	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
344609005734	MOSC domain; Region: MOSC; pfam03473
344609005735	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
344609005736	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
344609005737	catalytic loop [active]
344609005738	iron binding site [ion binding]; other site
344609005739	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
344609005740	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
344609005741	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
344609005742	quinone interaction residues [chemical binding]; other site
344609005743	active site
344609005744	catalytic residues [active]
344609005745	FMN binding site [chemical binding]; other site
344609005746	substrate binding site [chemical binding]; other site
344609005747	Fimbrial protein; Region: Fimbrial; cl01416
344609005748	Fimbrial protein; Region: Fimbrial; cl01416
344609005749	Fimbrial protein; Region: Fimbrial; cl01416
344609005750	outer membrane usher protein; Provisional; Region: PRK15193
344609005751	PapC N-terminal domain; Region: PapC_N; pfam13954
344609005752	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
344609005753	PapC C-terminal domain; Region: PapC_C; pfam13953
344609005754	Fimbrial protein; Region: Fimbrial; cl01416
344609005755	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
344609005756	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
344609005757	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
344609005758	substrate binding pocket [chemical binding]; other site
344609005759	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
344609005760	membrane-bound complex binding site; other site
344609005761	hinge residues; other site
344609005762	aminopeptidase N; Provisional; Region: pepN; PRK14015
344609005763	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
344609005764	active site
344609005765	Zn binding site [ion binding]; other site
344609005766	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
344609005767	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
344609005768	active site
344609005769	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
344609005770	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
344609005771	putative dimer interface [polypeptide binding]; other site
344609005772	putative anticodon binding site; other site
344609005773	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
344609005774	homodimer interface [polypeptide binding]; other site
344609005775	motif 1; other site
344609005776	motif 2; other site
344609005777	active site
344609005778	motif 3; other site
344609005779	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
344609005780	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
344609005781	trimer interface [polypeptide binding]; other site
344609005782	eyelet of channel; other site
344609005783	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
344609005784	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
344609005785	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609005786	homodimer interface [polypeptide binding]; other site
344609005787	catalytic residue [active]
344609005788	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
344609005789	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
344609005790	Peptidase M15; Region: Peptidase_M15_3; cl01194
344609005791	murein L,D-transpeptidase; Provisional; Region: PRK10594
344609005792	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
344609005793	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
344609005794	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
344609005795	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609005796	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609005797	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609005798	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609005799	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
344609005800	MukB N-terminal; Region: MukB; pfam04310
344609005801	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
344609005802	condesin subunit E; Provisional; Region: PRK05256
344609005803	condesin subunit F; Provisional; Region: PRK05260
344609005804	Methyltransferase domain; Region: Methyltransf_31; pfam13847
344609005805	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609005806	S-adenosylmethionine binding site [chemical binding]; other site
344609005807	Uncharacterized conserved protein [Function unknown]; Region: COG1434
344609005808	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
344609005809	putative active site [active]
344609005810	hypothetical protein; Provisional; Region: PRK10593
344609005811	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
344609005812	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
344609005813	Ligand binding site; other site
344609005814	oligomer interface; other site
344609005815	hypothetical protein; Provisional; Region: PRK11827
344609005816	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
344609005817	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
344609005818	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
344609005819	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
344609005820	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
344609005821	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
344609005822	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
344609005823	Walker A/P-loop; other site
344609005824	ATP binding site [chemical binding]; other site
344609005825	Q-loop/lid; other site
344609005826	ABC transporter signature motif; other site
344609005827	Walker B; other site
344609005828	D-loop; other site
344609005829	H-loop/switch region; other site
344609005830	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
344609005831	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
344609005832	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609005833	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609005834	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609005835	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609005836	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609005837	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609005838	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609005839	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
344609005840	IHF dimer interface [polypeptide binding]; other site
344609005841	IHF - DNA interface [nucleotide binding]; other site
344609005842	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
344609005843	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
344609005844	RNA binding site [nucleotide binding]; other site
344609005845	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
344609005846	RNA binding site [nucleotide binding]; other site
344609005847	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
344609005848	RNA binding site [nucleotide binding]; other site
344609005849	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
344609005850	RNA binding site [nucleotide binding]; other site
344609005851	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
344609005852	RNA binding site [nucleotide binding]; other site
344609005853	cytidylate kinase; Provisional; Region: cmk; PRK00023
344609005854	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
344609005855	CMP-binding site; other site
344609005856	The sites determining sugar specificity; other site
344609005857	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
344609005858	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
344609005859	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
344609005860	hinge; other site
344609005861	active site
344609005862	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
344609005863	homodimer interface [polypeptide binding]; other site
344609005864	substrate-cofactor binding pocket; other site
344609005865	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609005866	catalytic residue [active]
344609005867	Predicted membrane protein [Function unknown]; Region: COG2323
344609005868	uncharacterized domain; Region: TIGR00702
344609005869	YcaO-like family; Region: YcaO; pfam02624
344609005870	formate transporter; Provisional; Region: PRK10805
344609005871	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
344609005872	Pyruvate formate lyase 1; Region: PFL1; cd01678
344609005873	coenzyme A binding site [chemical binding]; other site
344609005874	active site
344609005875	catalytic residues [active]
344609005876	glycine loop; other site
344609005877	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
344609005878	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
344609005879	FeS/SAM binding site; other site
344609005880	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609005881	putative transposase OrfB; Reviewed; Region: PHA02517
344609005882	HTH-like domain; Region: HTH_21; pfam13276
344609005883	Integrase core domain; Region: rve; pfam00665
344609005884	Integrase core domain; Region: rve_3; pfam13683
344609005885	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
344609005886	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
344609005887	4Fe-4S binding domain; Region: Fer4; pfam00037
344609005888	seryl-tRNA synthetase; Provisional; Region: PRK05431
344609005889	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
344609005890	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
344609005891	dimer interface [polypeptide binding]; other site
344609005892	active site
344609005893	motif 1; other site
344609005894	motif 2; other site
344609005895	motif 3; other site
344609005896	recombination factor protein RarA; Reviewed; Region: PRK13342
344609005897	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609005898	Walker A motif; other site
344609005899	ATP binding site [chemical binding]; other site
344609005900	Walker B motif; other site
344609005901	arginine finger; other site
344609005902	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
344609005903	periplasmic chaperone LolA; Region: lolA; TIGR00547
344609005904	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
344609005905	DNA translocase FtsK; Provisional; Region: PRK10263
344609005906	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
344609005907	DNA translocase FtsK; Provisional; Region: PRK10263
344609005908	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
344609005909	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
344609005910	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
344609005911	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
344609005912	putative DNA binding site [nucleotide binding]; other site
344609005913	putative Zn2+ binding site [ion binding]; other site
344609005914	AsnC family; Region: AsnC_trans_reg; pfam01037
344609005915	thioredoxin reductase; Provisional; Region: PRK10262
344609005916	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
344609005917	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
344609005918	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
344609005919	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
344609005920	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609005921	Walker A/P-loop; other site
344609005922	ATP binding site [chemical binding]; other site
344609005923	Q-loop/lid; other site
344609005924	ABC transporter signature motif; other site
344609005925	Walker B; other site
344609005926	D-loop; other site
344609005927	H-loop/switch region; other site
344609005928	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
344609005929	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
344609005930	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
344609005931	Walker A/P-loop; other site
344609005932	ATP binding site [chemical binding]; other site
344609005933	Q-loop/lid; other site
344609005934	ABC transporter signature motif; other site
344609005935	Walker B; other site
344609005936	D-loop; other site
344609005937	H-loop/switch region; other site
344609005938	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
344609005939	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
344609005940	rRNA binding site [nucleotide binding]; other site
344609005941	predicted 30S ribosome binding site; other site
344609005942	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
344609005943	Clp amino terminal domain; Region: Clp_N; pfam02861
344609005944	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609005945	Walker A motif; other site
344609005946	ATP binding site [chemical binding]; other site
344609005947	Walker B motif; other site
344609005948	arginine finger; other site
344609005949	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609005950	Walker A motif; other site
344609005951	ATP binding site [chemical binding]; other site
344609005952	Walker B motif; other site
344609005953	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
344609005954	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
344609005955	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
344609005956	DNA-binding site [nucleotide binding]; DNA binding site
344609005957	RNA-binding motif; other site
344609005958	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
344609005959	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
344609005960	Walker A/P-loop; other site
344609005961	ATP binding site [chemical binding]; other site
344609005962	Q-loop/lid; other site
344609005963	ABC transporter signature motif; other site
344609005964	Walker B; other site
344609005965	D-loop; other site
344609005966	H-loop/switch region; other site
344609005967	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
344609005968	FtsX-like permease family; Region: FtsX; pfam02687
344609005969	macrolide transporter subunit MacA; Provisional; Region: PRK11578
344609005970	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
344609005971	HlyD family secretion protein; Region: HlyD_3; pfam13437
344609005972	Protein of unknown function (DUF535); Region: DUF535; pfam04393
344609005973	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
344609005974	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
344609005975	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
344609005976	putative active site [active]
344609005977	putative metal-binding site [ion binding]; other site
344609005978	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609005979	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
344609005980	amphipathic channel; other site
344609005981	Asn-Pro-Ala signature motifs; other site
344609005982	Predicted membrane protein [Function unknown]; Region: COG2431
344609005983	hybrid cluster protein; Provisional; Region: PRK05290
344609005984	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
344609005985	ACS interaction site; other site
344609005986	CODH interaction site; other site
344609005987	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
344609005988	hybrid metal cluster; other site
344609005989	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
344609005990	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
344609005991	FAD binding pocket [chemical binding]; other site
344609005992	FAD binding motif [chemical binding]; other site
344609005993	phosphate binding motif [ion binding]; other site
344609005994	beta-alpha-beta structure motif; other site
344609005995	NAD binding pocket [chemical binding]; other site
344609005996	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
344609005997	catalytic loop [active]
344609005998	iron binding site [ion binding]; other site
344609005999	pyruvate dehydrogenase; Provisional; Region: PRK09124
344609006000	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
344609006001	PYR/PP interface [polypeptide binding]; other site
344609006002	dimer interface [polypeptide binding]; other site
344609006003	tetramer interface [polypeptide binding]; other site
344609006004	TPP binding site [chemical binding]; other site
344609006005	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
344609006006	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
344609006007	TPP-binding site [chemical binding]; other site
344609006008	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
344609006009	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
344609006010	tetramer interface [polypeptide binding]; other site
344609006011	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609006012	catalytic residue [active]
344609006013	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
344609006014	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
344609006015	putative NAD(P) binding site [chemical binding]; other site
344609006016	putative active site [active]
344609006017	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
344609006018	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
344609006019	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
344609006020	NAD(P) binding site [chemical binding]; other site
344609006021	active site
344609006022	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
344609006023	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
344609006024	amidase catalytic site [active]
344609006025	Zn binding residues [ion binding]; other site
344609006026	substrate binding site [chemical binding]; other site
344609006027	hypothetical protein; Provisional; Region: PRK02877
344609006028	putative lipoprotein; Provisional; Region: PRK10533
344609006029	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
344609006030	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609006031	Walker A/P-loop; other site
344609006032	ATP binding site [chemical binding]; other site
344609006033	Q-loop/lid; other site
344609006034	ABC transporter signature motif; other site
344609006035	Walker B; other site
344609006036	D-loop; other site
344609006037	H-loop/switch region; other site
344609006038	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
344609006039	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
344609006040	substrate binding pocket [chemical binding]; other site
344609006041	membrane-bound complex binding site; other site
344609006042	hinge residues; other site
344609006043	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
344609006044	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609006045	dimer interface [polypeptide binding]; other site
344609006046	conserved gate region; other site
344609006047	putative PBP binding loops; other site
344609006048	ABC-ATPase subunit interface; other site
344609006049	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609006050	dimer interface [polypeptide binding]; other site
344609006051	conserved gate region; other site
344609006052	putative PBP binding loops; other site
344609006053	ABC-ATPase subunit interface; other site
344609006054	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
344609006055	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
344609006056	substrate binding pocket [chemical binding]; other site
344609006057	membrane-bound complex binding site; other site
344609006058	hinge residues; other site
344609006059	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
344609006060	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609006061	S-adenosylmethionine binding site [chemical binding]; other site
344609006062	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
344609006063	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
344609006064	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609006065	dimer interface [polypeptide binding]; other site
344609006066	conserved gate region; other site
344609006067	putative PBP binding loops; other site
344609006068	ABC-ATPase subunit interface; other site
344609006069	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
344609006070	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609006071	dimer interface [polypeptide binding]; other site
344609006072	conserved gate region; other site
344609006073	putative PBP binding loops; other site
344609006074	ABC-ATPase subunit interface; other site
344609006075	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
344609006076	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609006077	Walker A/P-loop; other site
344609006078	ATP binding site [chemical binding]; other site
344609006079	Q-loop/lid; other site
344609006080	ABC transporter signature motif; other site
344609006081	Walker B; other site
344609006082	D-loop; other site
344609006083	H-loop/switch region; other site
344609006084	TOBE domain; Region: TOBE_2; pfam08402
344609006085	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
344609006086	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
344609006087	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
344609006088	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
344609006089	RimK-like ATP-grasp domain; Region: RimK; pfam08443
344609006090	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
344609006091	dimer interface [polypeptide binding]; other site
344609006092	FMN binding site [chemical binding]; other site
344609006093	NADPH bind site [chemical binding]; other site
344609006094	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
344609006095	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
344609006096	GSH binding site [chemical binding]; other site
344609006097	catalytic residues [active]
344609006098	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
344609006099	putative transporter; Provisional; Region: PRK04972
344609006100	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
344609006101	TrkA-C domain; Region: TrkA_C; pfam02080
344609006102	TrkA-C domain; Region: TrkA_C; pfam02080
344609006103	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
344609006104	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
344609006105	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
344609006106	tail protein; Provisional; Region: D; PHA02561
344609006107	Phage protein U [General function prediction only]; Region: COG3499
344609006108	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
344609006109	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
344609006110	major tail tube protein; Provisional; Region: FII; PHA02600
344609006111	major tail sheath protein; Provisional; Region: FI; PHA02560
344609006112	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609006113	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609006114	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609006115	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609006116	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
344609006117	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
344609006118	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
344609006119	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609006120	putative substrate translocation pore; other site
344609006121	Major Facilitator Superfamily; Region: MFS_1; pfam07690
344609006122	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
344609006123	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609006124	active site
344609006125	motif I; other site
344609006126	motif II; other site
344609006127	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609006128	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
344609006129	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
344609006130	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
344609006131	active site
344609006132	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
344609006133	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
344609006134	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
344609006135	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
344609006136	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
344609006137	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
344609006138	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
344609006139	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
344609006140	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
344609006141	N-terminal domain interface [polypeptide binding]; other site
344609006142	dimer interface [polypeptide binding]; other site
344609006143	substrate binding pocket (H-site) [chemical binding]; other site
344609006144	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
344609006145	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
344609006146	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
344609006147	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
344609006148	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
344609006149	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
344609006150	FeS/SAM binding site; other site
344609006151	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
344609006152	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609006153	Transposase; Region: HTH_Tnp_1; pfam01527
344609006154	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
344609006155	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
344609006156	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609006157	dimer interface [polypeptide binding]; other site
344609006158	conserved gate region; other site
344609006159	putative PBP binding loops; other site
344609006160	ABC-ATPase subunit interface; other site
344609006161	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
344609006162	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609006163	dimer interface [polypeptide binding]; other site
344609006164	conserved gate region; other site
344609006165	putative PBP binding loops; other site
344609006166	ABC-ATPase subunit interface; other site
344609006167	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
344609006168	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
344609006169	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
344609006170	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
344609006171	Walker A/P-loop; other site
344609006172	ATP binding site [chemical binding]; other site
344609006173	Q-loop/lid; other site
344609006174	ABC transporter signature motif; other site
344609006175	Walker B; other site
344609006176	D-loop; other site
344609006177	H-loop/switch region; other site
344609006178	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
344609006179	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
344609006180	Walker A/P-loop; other site
344609006181	ATP binding site [chemical binding]; other site
344609006182	Q-loop/lid; other site
344609006183	ABC transporter signature motif; other site
344609006184	Walker B; other site
344609006185	D-loop; other site
344609006186	H-loop/switch region; other site
344609006187	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
344609006188	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
344609006189	catalytic nucleophile [active]
344609006190	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
344609006191	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
344609006192	dimer interface [polypeptide binding]; other site
344609006193	putative functional site; other site
344609006194	putative MPT binding site; other site
344609006195	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
344609006196	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
344609006197	ATP binding site [chemical binding]; other site
344609006198	substrate interface [chemical binding]; other site
344609006199	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
344609006200	active site
344609006201	intersubunit interactions; other site
344609006202	catalytic residue [active]
344609006203	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
344609006204	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
344609006205	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
344609006206	dimer interface [polypeptide binding]; other site
344609006207	active site
344609006208	glycine loop; other site
344609006209	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
344609006210	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609006211	active site
344609006212	motif I; other site
344609006213	motif II; other site
344609006214	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609006215	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
344609006216	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
344609006217	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609006218	Walker A/P-loop; other site
344609006219	ATP binding site [chemical binding]; other site
344609006220	Q-loop/lid; other site
344609006221	ABC transporter signature motif; other site
344609006222	Walker B; other site
344609006223	D-loop; other site
344609006224	H-loop/switch region; other site
344609006225	ABC transporter; Region: ABC_tran_2; pfam12848
344609006226	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
344609006227	L,D-transpeptidase; Provisional; Region: PRK10260
344609006228	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
344609006229	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
344609006230	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
344609006231	transmembrane helices; other site
344609006232	manganese transport regulator MntR; Provisional; Region: PRK11050
344609006233	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
344609006234	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
344609006235	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
344609006236	Sulfatase; Region: Sulfatase; pfam00884
344609006237	outer membrane protein X; Provisional; Region: ompX; PRK09408
344609006238	threonine and homoserine efflux system; Provisional; Region: PRK10532
344609006239	EamA-like transporter family; Region: EamA; pfam00892
344609006240	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
344609006241	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
344609006242	dimerization interface [polypeptide binding]; other site
344609006243	DPS ferroxidase diiron center [ion binding]; other site
344609006244	ion pore; other site
344609006245	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
344609006246	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
344609006247	substrate binding pocket [chemical binding]; other site
344609006248	membrane-bound complex binding site; other site
344609006249	hinge residues; other site
344609006250	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
344609006251	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609006252	dimer interface [polypeptide binding]; other site
344609006253	conserved gate region; other site
344609006254	putative PBP binding loops; other site
344609006255	ABC-ATPase subunit interface; other site
344609006256	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
344609006257	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
344609006258	Walker A/P-loop; other site
344609006259	ATP binding site [chemical binding]; other site
344609006260	Q-loop/lid; other site
344609006261	ABC transporter signature motif; other site
344609006262	Walker B; other site
344609006263	D-loop; other site
344609006264	H-loop/switch region; other site
344609006265	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609006266	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609006267	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
344609006268	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
344609006269	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
344609006270	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
344609006271	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609006272	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609006273	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609006274	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
344609006275	hypothetical protein; Provisional; Region: PRK11019
344609006276	hypothetical protein; Provisional; Region: PRK10259
344609006277	putative dehydrogenase; Provisional; Region: PRK10098
344609006278	glycosyl transferase family protein; Provisional; Region: PRK08136
344609006279	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
344609006280	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
344609006281	DEAD_2; Region: DEAD_2; pfam06733
344609006282	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
344609006283	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3236
344609006284	helicase 45; Provisional; Region: PTZ00424
344609006285	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
344609006286	ATP binding site [chemical binding]; other site
344609006287	Mg++ binding site [ion binding]; other site
344609006288	motif III; other site
344609006289	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
344609006290	nucleotide binding region [chemical binding]; other site
344609006291	ATP-binding site [chemical binding]; other site
344609006292	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
344609006293	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
344609006294	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
344609006295	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
344609006296	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
344609006297	HlyD family secretion protein; Region: HlyD_3; pfam13437
344609006298	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
344609006299	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
344609006300	Walker A/P-loop; other site
344609006301	ATP binding site [chemical binding]; other site
344609006302	Q-loop/lid; other site
344609006303	ABC transporter signature motif; other site
344609006304	Walker B; other site
344609006305	D-loop; other site
344609006306	H-loop/switch region; other site
344609006307	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
344609006308	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
344609006309	Walker A/P-loop; other site
344609006310	ATP binding site [chemical binding]; other site
344609006311	Q-loop/lid; other site
344609006312	ABC transporter signature motif; other site
344609006313	Walker B; other site
344609006314	D-loop; other site
344609006315	H-loop/switch region; other site
344609006316	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
344609006317	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
344609006318	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
344609006319	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
344609006320	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
344609006321	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
344609006322	putative catalytic site [active]
344609006323	putative metal binding site [ion binding]; other site
344609006324	putative phosphate binding site [ion binding]; other site
344609006325	cardiolipin synthase 2; Provisional; Region: PRK11263
344609006326	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
344609006327	putative active site [active]
344609006328	catalytic site [active]
344609006329	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
344609006330	putative active site [active]
344609006331	catalytic site [active]
344609006332	Predicted integral membrane protein [Function unknown]; Region: COG0392
344609006333	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
344609006334	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
344609006335	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
344609006336	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
344609006337	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
344609006338	MoaE homodimer interface [polypeptide binding]; other site
344609006339	MoaD interaction [polypeptide binding]; other site
344609006340	active site residues [active]
344609006341	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
344609006342	MoaE interaction surface [polypeptide binding]; other site
344609006343	MoeB interaction surface [polypeptide binding]; other site
344609006344	thiocarboxylated glycine; other site
344609006345	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
344609006346	trimer interface [polypeptide binding]; other site
344609006347	dimer interface [polypeptide binding]; other site
344609006348	putative active site [active]
344609006349	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
344609006350	MPT binding site; other site
344609006351	trimer interface [polypeptide binding]; other site
344609006352	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
344609006353	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
344609006354	FeS/SAM binding site; other site
344609006355	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
344609006356	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
344609006357	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
344609006358	putative substrate binding pocket [chemical binding]; other site
344609006359	dimer interface [polypeptide binding]; other site
344609006360	phosphate binding site [ion binding]; other site
344609006361	excinuclease ABC subunit B; Provisional; Region: PRK05298
344609006362	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
344609006363	ATP binding site [chemical binding]; other site
344609006364	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
344609006365	nucleotide binding region [chemical binding]; other site
344609006366	ATP-binding site [chemical binding]; other site
344609006367	Ultra-violet resistance protein B; Region: UvrB; pfam12344
344609006368	UvrB/uvrC motif; Region: UVR; pfam02151
344609006369	AAA domain; Region: AAA_26; pfam13500
344609006370	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
344609006371	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
344609006372	ADP binding site [chemical binding]; other site
344609006373	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
344609006374	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609006375	S-adenosylmethionine binding site [chemical binding]; other site
344609006376	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
344609006377	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
344609006378	substrate-cofactor binding pocket; other site
344609006379	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609006380	catalytic residue [active]
344609006381	biotin synthase; Provisional; Region: PRK15108
344609006382	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
344609006383	FeS/SAM binding site; other site
344609006384	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
344609006385	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
344609006386	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
344609006387	inhibitor-cofactor binding pocket; inhibition site
344609006388	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609006389	catalytic residue [active]
344609006390	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
344609006391	substrate binding site [chemical binding]; other site
344609006392	acyl-CoA thioesterase; Provisional; Region: PRK10531
344609006393	putative pectinesterase; Region: PLN02432; cl01911
344609006394	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
344609006395	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
344609006396	PrpF protein; Region: PrpF; pfam04303
344609006397	Transcriptional regulator [Transcription]; Region: LysR; COG0583
344609006398	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609006399	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
344609006400	putative dimerization interface [polypeptide binding]; other site
344609006401	6-phosphogluconolactonase; Provisional; Region: PRK11028
344609006402	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
344609006403	E3 ubiquitin-protein ligase SspH2; Provisional; Region: PRK15387
344609006404	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
344609006405	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
344609006406	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609006407	HTH-like domain; Region: HTH_21; pfam13276
344609006408	Integrase core domain; Region: rve; pfam00665
344609006409	Integrase core domain; Region: rve_3; pfam13683
344609006410	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609006411	Transposase; Region: HTH_Tnp_1; pfam01527
344609006412	Transposase; Region: HTH_Tnp_1; cl17663
344609006413	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609006414	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609006415	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609006416	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609006417	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609006418	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609006419	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609006420	Uncharacterized protein conserved in bacteria (DUF2138); Region: DUF2138; cl01916
344609006421	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609006422	Transposase; Region: HTH_Tnp_1; pfam01527
344609006423	DNA gyrase subunit A; Validated; Region: PRK05560
344609006424	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
344609006425	CAP-like domain; other site
344609006426	active site
344609006427	primary dimer interface [polypeptide binding]; other site
344609006428	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
344609006429	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
344609006430	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
344609006431	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
344609006432	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
344609006433	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
344609006434	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
344609006435	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609006436	S-adenosylmethionine binding site [chemical binding]; other site
344609006437	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609006438	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609006439	HTH-like domain; Region: HTH_21; pfam13276
344609006440	Integrase core domain; Region: rve; pfam00665
344609006441	Integrase core domain; Region: rve_3; pfam13683
344609006442	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
344609006443	ATP cone domain; Region: ATP-cone; pfam03477
344609006444	Class I ribonucleotide reductase; Region: RNR_I; cd01679
344609006445	active site
344609006446	dimer interface [polypeptide binding]; other site
344609006447	catalytic residues [active]
344609006448	effector binding site; other site
344609006449	R2 peptide binding site; other site
344609006450	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
344609006451	dimer interface [polypeptide binding]; other site
344609006452	putative radical transfer pathway; other site
344609006453	diiron center [ion binding]; other site
344609006454	tyrosyl radical; other site
344609006455	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
344609006456	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
344609006457	catalytic loop [active]
344609006458	iron binding site [ion binding]; other site
344609006459	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609006460	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609006461	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609006462	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609006463	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609006464	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609006465	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609006466	hypothetical protein; Provisional; Region: PRK09729
344609006467	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
344609006468	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
344609006469	active site
344609006470	catalytic site [active]
344609006471	metal binding site [ion binding]; metal-binding site
344609006472	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
344609006473	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609006474	putative substrate translocation pore; other site
344609006475	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
344609006476	hydroxyglutarate oxidase; Provisional; Region: PRK11728
344609006477	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
344609006478	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
344609006479	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
344609006480	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
344609006481	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
344609006482	Cysteine-rich domain; Region: CCG; pfam02754
344609006483	Cysteine-rich domain; Region: CCG; pfam02754
344609006484	hypothetical protein; Provisional; Region: PRK09956
344609006485	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
344609006486	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609006487	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
344609006488	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
344609006489	active site
344609006490	hexamer interface [polypeptide binding]; other site
344609006491	NAD-dependent epimerase/dehydratase family protein; Provisional; Region: PRK11908
344609006492	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
344609006493	NAD binding site [chemical binding]; other site
344609006494	substrate binding site [chemical binding]; other site
344609006495	active site
344609006496	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
344609006497	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
344609006498	putative active site [active]
344609006499	putative catalytic site [active]
344609006500	putative Zn binding site [ion binding]; other site
344609006501	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
344609006502	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
344609006503	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
344609006504	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609006505	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609006506	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609006507	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609006508	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609006509	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609006510	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609006511	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
344609006512	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
344609006513	acyl-activating enzyme (AAE) consensus motif; other site
344609006514	putative AMP binding site [chemical binding]; other site
344609006515	putative active site [active]
344609006516	putative CoA binding site [chemical binding]; other site
344609006517	O-succinylbenzoate synthase; Provisional; Region: PRK05105
344609006518	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
344609006519	active site
344609006520	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
344609006521	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
344609006522	substrate binding site [chemical binding]; other site
344609006523	oxyanion hole (OAH) forming residues; other site
344609006524	trimer interface [polypeptide binding]; other site
344609006525	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
344609006526	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
344609006527	nucleophilic elbow; other site
344609006528	catalytic triad; other site
344609006529	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
344609006530	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
344609006531	dimer interface [polypeptide binding]; other site
344609006532	tetramer interface [polypeptide binding]; other site
344609006533	PYR/PP interface [polypeptide binding]; other site
344609006534	TPP binding site [chemical binding]; other site
344609006535	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
344609006536	TPP-binding site; other site
344609006537	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
344609006538	isochorismate synthases; Region: isochor_syn; TIGR00543
344609006539	hypothetical protein; Provisional; Region: PRK10404
344609006540	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
344609006541	Coenzyme A binding pocket [chemical binding]; other site
344609006542	ribonuclease BN; Region: true_RNase_BN; TIGR02649
344609006543	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609006544	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
344609006545	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
344609006546	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
344609006547	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
344609006548	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
344609006549	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
344609006550	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
344609006551	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
344609006552	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
344609006553	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
344609006554	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
344609006555	4Fe-4S binding domain; Region: Fer4; pfam00037
344609006556	4Fe-4S binding domain; Region: Fer4; pfam00037
344609006557	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
344609006558	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
344609006559	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
344609006560	catalytic loop [active]
344609006561	iron binding site [ion binding]; other site
344609006562	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
344609006563	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
344609006564	[4Fe-4S] binding site [ion binding]; other site
344609006565	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
344609006566	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
344609006567	SLBB domain; Region: SLBB; pfam10531
344609006568	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
344609006569	NADH dehydrogenase subunit E; Validated; Region: PRK07539
344609006570	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
344609006571	putative dimer interface [polypeptide binding]; other site
344609006572	[2Fe-2S] cluster binding site [ion binding]; other site
344609006573	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
344609006574	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
344609006575	NADH dehydrogenase subunit D; Validated; Region: PRK06075
344609006576	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
344609006577	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
344609006578	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
344609006579	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609006580	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
344609006581	putative dimerization interface [polypeptide binding]; other site
344609006582	aminotransferase AlaT; Validated; Region: PRK09265
344609006583	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
344609006584	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609006585	homodimer interface [polypeptide binding]; other site
344609006586	catalytic residue [active]
344609006587	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
344609006588	Zn2+ binding site [ion binding]; other site
344609006589	Mg2+ binding site [ion binding]; other site
344609006590	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
344609006591	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
344609006592	TrkA-C domain; Region: TrkA_C; pfam02080
344609006593	TrkA-C domain; Region: TrkA_C; pfam02080
344609006594	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
344609006595	putative phosphatase; Provisional; Region: PRK11587
344609006596	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609006597	motif II; other site
344609006598	hypothetical protein; Validated; Region: PRK05445
344609006599	hypothetical protein; Provisional; Region: PRK01816
344609006600	propionate/acetate kinase; Provisional; Region: PRK12379
344609006601	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
344609006602	phosphate acetyltransferase; Reviewed; Region: PRK05632
344609006603	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
344609006604	DRTGG domain; Region: DRTGG; pfam07085
344609006605	phosphate acetyltransferase; Region: pta; TIGR00651
344609006606	hypothetical protein; Provisional; Region: PRK11588
344609006607	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
344609006608	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
344609006609	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
344609006610	nudix motif; other site
344609006611	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
344609006612	active site
344609006613	metal binding site [ion binding]; metal-binding site
344609006614	homotetramer interface [polypeptide binding]; other site
344609006615	glutathione S-transferase; Provisional; Region: PRK15113
344609006616	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
344609006617	C-terminal domain interface [polypeptide binding]; other site
344609006618	GSH binding site (G-site) [chemical binding]; other site
344609006619	dimer interface [polypeptide binding]; other site
344609006620	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
344609006621	N-terminal domain interface [polypeptide binding]; other site
344609006622	putative dimer interface [polypeptide binding]; other site
344609006623	putative substrate binding pocket (H-site) [chemical binding]; other site
344609006624	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
344609006625	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
344609006626	C-terminal domain interface [polypeptide binding]; other site
344609006627	GSH binding site (G-site) [chemical binding]; other site
344609006628	dimer interface [polypeptide binding]; other site
344609006629	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
344609006630	N-terminal domain interface [polypeptide binding]; other site
344609006631	putative dimer interface [polypeptide binding]; other site
344609006632	active site
344609006633	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
344609006634	homooctamer interface [polypeptide binding]; other site
344609006635	active site
344609006636	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
344609006637	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
344609006638	putative NAD(P) binding site [chemical binding]; other site
344609006639	putative active site [active]
344609006640	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609006641	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
344609006642	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
344609006643	Walker A/P-loop; other site
344609006644	ATP binding site [chemical binding]; other site
344609006645	Q-loop/lid; other site
344609006646	ABC transporter signature motif; other site
344609006647	Walker B; other site
344609006648	D-loop; other site
344609006649	H-loop/switch region; other site
344609006650	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609006651	dimer interface [polypeptide binding]; other site
344609006652	conserved gate region; other site
344609006653	putative PBP binding loops; other site
344609006654	ABC-ATPase subunit interface; other site
344609006655	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
344609006656	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609006657	dimer interface [polypeptide binding]; other site
344609006658	conserved gate region; other site
344609006659	putative PBP binding loops; other site
344609006660	ABC-ATPase subunit interface; other site
344609006661	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
344609006662	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
344609006663	substrate binding pocket [chemical binding]; other site
344609006664	membrane-bound complex binding site; other site
344609006665	hinge residues; other site
344609006666	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
344609006667	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
344609006668	substrate binding pocket [chemical binding]; other site
344609006669	membrane-bound complex binding site; other site
344609006670	hinge residues; other site
344609006671	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
344609006672	Flavoprotein; Region: Flavoprotein; pfam02441
344609006673	amidophosphoribosyltransferase; Provisional; Region: PRK09246
344609006674	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
344609006675	active site
344609006676	tetramer interface [polypeptide binding]; other site
344609006677	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
344609006678	active site
344609006679	colicin V production protein; Provisional; Region: PRK10845
344609006680	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
344609006681	cell division protein DedD; Provisional; Region: PRK11633
344609006682	Sporulation related domain; Region: SPOR; pfam05036
344609006683	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
344609006684	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
344609006685	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
344609006686	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
344609006687	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
344609006688	hypothetical protein; Provisional; Region: PRK10847
344609006689	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
344609006690	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
344609006691	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
344609006692	dimerization interface 3.5A [polypeptide binding]; other site
344609006693	active site
344609006694	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
344609006695	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
344609006696	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
344609006697	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
344609006698	ligand binding site [chemical binding]; other site
344609006699	NAD binding site [chemical binding]; other site
344609006700	catalytic site [active]
344609006701	homodimer interface [polypeptide binding]; other site
344609006702	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
344609006703	putative transporter; Provisional; Region: PRK12382
344609006704	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609006705	putative substrate translocation pore; other site
344609006706	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
344609006707	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
344609006708	dimer interface [polypeptide binding]; other site
344609006709	active site
344609006710	Uncharacterized conserved protein [Function unknown]; Region: COG4121
344609006711	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
344609006712	YfcL protein; Region: YfcL; pfam08891
344609006713	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
344609006714	hypothetical protein; Provisional; Region: PRK10621
344609006715	Predicted permeases [General function prediction only]; Region: COG0730
344609006716	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
344609006717	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
344609006718	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
344609006719	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
344609006720	Tetramer interface [polypeptide binding]; other site
344609006721	active site
344609006722	FMN-binding site [chemical binding]; other site
344609006723	HemK family putative methylases; Region: hemK_fam; TIGR00536
344609006724	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609006725	S-adenosylmethionine binding site [chemical binding]; other site
344609006726	hypothetical protein; Provisional; Region: PRK04946
344609006727	Smr domain; Region: Smr; pfam01713
344609006728	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
344609006729	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609006730	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609006731	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609006732	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609006733	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609006734	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609006735	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609006736	Fimbrial protein; Region: Fimbrial; cl01416
344609006737	Fimbrial protein; Region: Fimbrial; cl01416
344609006738	Fimbrial protein; Region: Fimbrial; cl01416
344609006739	putative fimbrial chaperone protein StfD; Provisional; Region: PRK15285
344609006740	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
344609006741	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
344609006742	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
344609006743	PapC N-terminal domain; Region: PapC_N; pfam13954
344609006744	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
344609006745	PapC C-terminal domain; Region: PapC_C; pfam13953
344609006746	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
344609006747	catalytic core [active]
344609006748	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
344609006749	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
344609006750	substrate binding site [chemical binding]; other site
344609006751	oxyanion hole (OAH) forming residues; other site
344609006752	trimer interface [polypeptide binding]; other site
344609006753	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
344609006754	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
344609006755	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
344609006756	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
344609006757	dimer interface [polypeptide binding]; other site
344609006758	active site
344609006759	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
344609006760	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
344609006761	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609006762	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609006763	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609006764	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
344609006765	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
344609006766	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609006767	Transposase; Region: HTH_Tnp_1; pfam01527
344609006768	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
344609006769	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
344609006770	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
344609006771	catalytic residue [active]
344609006772	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
344609006773	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609006774	putative substrate translocation pore; other site
344609006775	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609006776	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
344609006777	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
344609006778	HlyD family secretion protein; Region: HlyD_3; pfam13437
344609006779	DNA-binding transcriptional activator EvgA; Provisional; Region: PRK09958
344609006780	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609006781	active site
344609006782	phosphorylation site [posttranslational modification]
344609006783	intermolecular recognition site; other site
344609006784	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
344609006785	DNA binding residues [nucleotide binding]
344609006786	dimerization interface [polypeptide binding]; other site
344609006787	hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959
344609006788	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
344609006789	substrate binding pocket [chemical binding]; other site
344609006790	membrane-bound complex binding site; other site
344609006791	hinge residues; other site
344609006792	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
344609006793	substrate binding pocket [chemical binding]; other site
344609006794	membrane-bound complex binding site; other site
344609006795	hinge residues; other site
344609006796	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609006797	dimer interface [polypeptide binding]; other site
344609006798	phosphorylation site [posttranslational modification]
344609006799	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609006800	ATP binding site [chemical binding]; other site
344609006801	Mg2+ binding site [ion binding]; other site
344609006802	G-X-G motif; other site
344609006803	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609006804	active site
344609006805	phosphorylation site [posttranslational modification]
344609006806	intermolecular recognition site; other site
344609006807	dimerization interface [polypeptide binding]; other site
344609006808	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
344609006809	putative binding surface; other site
344609006810	active site
344609006811	putative CoA-transferase; Provisional; Region: PRK11430
344609006812	CoA-transferase family III; Region: CoA_transf_3; pfam02515
344609006813	putative transporter YfdV; Provisional; Region: PRK09903
344609006814	putative oxalyl-CoA decarboxylase; Validated; Region: PRK09259
344609006815	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
344609006816	PYR/PP interface [polypeptide binding]; other site
344609006817	dimer interface [polypeptide binding]; other site
344609006818	TPP binding site [chemical binding]; other site
344609006819	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
344609006820	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
344609006821	TPP-binding site; other site
344609006822	dimer interface [polypeptide binding]; other site
344609006823	formyl-coenzyme A transferase; Provisional; Region: PRK05398
344609006824	CoA-transferase family III; Region: CoA_transf_3; pfam02515
344609006825	hypothetical protein; Provisional; Region: PRK10316
344609006826	YfdX protein; Region: YfdX; pfam10938
344609006827	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
344609006828	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
344609006829	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
344609006830	putative acyl-acceptor binding pocket; other site
344609006831	aminotransferase; Validated; Region: PRK08175
344609006832	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
344609006833	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609006834	homodimer interface [polypeptide binding]; other site
344609006835	catalytic residue [active]
344609006836	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
344609006837	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
344609006838	GAF domain; Region: GAF; pfam01590
344609006839	Histidine kinase; Region: His_kinase; pfam06580
344609006840	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609006841	ATP binding site [chemical binding]; other site
344609006842	Mg2+ binding site [ion binding]; other site
344609006843	G-X-G motif; other site
344609006844	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
344609006845	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609006846	active site
344609006847	phosphorylation site [posttranslational modification]
344609006848	intermolecular recognition site; other site
344609006849	dimerization interface [polypeptide binding]; other site
344609006850	LytTr DNA-binding domain; Region: LytTR; pfam04397
344609006851	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
344609006852	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609006853	aminopeptidase; Provisional; Region: PRK09795
344609006854	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
344609006855	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
344609006856	active site
344609006857	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
344609006858	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
344609006859	active site
344609006860	P-loop; other site
344609006861	phosphorylation site [posttranslational modification]
344609006862	glucokinase, proteobacterial type; Region: glk; TIGR00749
344609006863	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
344609006864	nucleotide binding site [chemical binding]; other site
344609006865	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
344609006866	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
344609006867	Cl- selectivity filter; other site
344609006868	Cl- binding residues [ion binding]; other site
344609006869	pore gating glutamate residue; other site
344609006870	dimer interface [polypeptide binding]; other site
344609006871	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
344609006872	manganese transport protein MntH; Reviewed; Region: PRK00701
344609006873	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
344609006874	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
344609006875	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
344609006876	Nucleoside recognition; Region: Gate; pfam07670
344609006877	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
344609006878	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609006879	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609006880	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609006881	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
344609006882	HPr interaction site; other site
344609006883	glycerol kinase (GK) interaction site [polypeptide binding]; other site
344609006884	active site
344609006885	phosphorylation site [posttranslational modification]
344609006886	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
344609006887	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
344609006888	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
344609006889	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
344609006890	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
344609006891	dimerization domain swap beta strand [polypeptide binding]; other site
344609006892	regulatory protein interface [polypeptide binding]; other site
344609006893	active site
344609006894	regulatory phosphorylation site [posttranslational modification]; other site
344609006895	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
344609006896	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
344609006897	dimer interface [polypeptide binding]; other site
344609006898	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609006899	catalytic residue [active]
344609006900	putative sulfate transport protein CysZ; Validated; Region: PRK04949
344609006901	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
344609006902	cell division protein ZipA; Provisional; Region: PRK03427
344609006903	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
344609006904	FtsZ protein binding site [polypeptide binding]; other site
344609006905	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
344609006906	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
344609006907	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
344609006908	Transcriptional regulator [Transcription]; Region: LysR; COG0583
344609006909	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609006910	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
344609006911	putative dimerization interface [polypeptide binding]; other site
344609006912	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
344609006913	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
344609006914	active site
344609006915	HIGH motif; other site
344609006916	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
344609006917	active site
344609006918	KMSKS motif; other site
344609006919	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
344609006920	salt bridge; other site
344609006921	non-specific DNA binding site [nucleotide binding]; other site
344609006922	sequence-specific DNA binding site [nucleotide binding]; other site
344609006923	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
344609006924	MASE1; Region: MASE1; pfam05231
344609006925	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609006926	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609006927	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609006928	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
344609006929	dimer interface [polypeptide binding]; other site
344609006930	pyridoxamine kinase; Validated; Region: PRK05756
344609006931	pyridoxal binding site [chemical binding]; other site
344609006932	ATP binding site [chemical binding]; other site
344609006933	hypothetical protein; Provisional; Region: PRK10318
344609006934	cysteine synthase B; Region: cysM; TIGR01138
344609006935	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
344609006936	dimer interface [polypeptide binding]; other site
344609006937	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609006938	catalytic residue [active]
344609006939	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
344609006940	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
344609006941	Walker A/P-loop; other site
344609006942	ATP binding site [chemical binding]; other site
344609006943	Q-loop/lid; other site
344609006944	ABC transporter signature motif; other site
344609006945	Walker B; other site
344609006946	D-loop; other site
344609006947	H-loop/switch region; other site
344609006948	TOBE-like domain; Region: TOBE_3; pfam12857
344609006949	sulfate transport protein; Provisional; Region: cysT; CHL00187
344609006950	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609006951	dimer interface [polypeptide binding]; other site
344609006952	conserved gate region; other site
344609006953	putative PBP binding loops; other site
344609006954	ABC-ATPase subunit interface; other site
344609006955	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
344609006956	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609006957	dimer interface [polypeptide binding]; other site
344609006958	conserved gate region; other site
344609006959	putative PBP binding loops; other site
344609006960	ABC-ATPase subunit interface; other site
344609006961	thiosulfate transporter subunit; Provisional; Region: PRK10852
344609006962	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
344609006963	short chain dehydrogenase; Provisional; Region: PRK08226
344609006964	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
344609006965	NAD binding site [chemical binding]; other site
344609006966	homotetramer interface [polypeptide binding]; other site
344609006967	homodimer interface [polypeptide binding]; other site
344609006968	active site
344609006969	transcriptional regulator MurR; Provisional; Region: PRK15482
344609006970	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
344609006971	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
344609006972	putative active site [active]
344609006973	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
344609006974	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
344609006975	putative active site [active]
344609006976	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
344609006977	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
344609006978	active site turn [active]
344609006979	phosphorylation site [posttranslational modification]
344609006980	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
344609006981	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
344609006982	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
344609006983	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
344609006984	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
344609006985	putative acetyltransferase; Provisional; Region: PRK03624
344609006986	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
344609006987	Coenzyme A binding pocket [chemical binding]; other site
344609006988	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
344609006989	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
344609006990	active site
344609006991	metal binding site [ion binding]; metal-binding site
344609006992	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
344609006993	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
344609006994	transcriptional regulator EutR; Provisional; Region: PRK10130
344609006995	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609006996	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609006997	carboxysome structural protein EutK; Provisional; Region: PRK15466
344609006998	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
344609006999	Hexamer interface [polypeptide binding]; other site
344609007000	Hexagonal pore residue; other site
344609007001	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
344609007002	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
344609007003	putative hexamer interface [polypeptide binding]; other site
344609007004	putative hexagonal pore; other site
344609007005	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
344609007006	putative hexamer interface [polypeptide binding]; other site
344609007007	putative hexagonal pore; other site
344609007008	Ethanolamine ammonia-lyase light chain (EutC); Region: EutC; cl01762
344609007009	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609007010	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
344609007011	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
344609007012	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
344609007013	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
344609007014	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
344609007015	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
344609007016	active site
344609007017	metal binding site [ion binding]; metal-binding site
344609007018	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
344609007019	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
344609007020	nucleotide binding site [chemical binding]; other site
344609007021	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
344609007022	putative catalytic cysteine [active]
344609007023	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
344609007024	Hexamer/Pentamer interface [polypeptide binding]; other site
344609007025	central pore; other site
344609007026	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
344609007027	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
344609007028	Hexamer interface [polypeptide binding]; other site
344609007029	Putative hexagonal pore residue; other site
344609007030	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
344609007031	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
344609007032	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
344609007033	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
344609007034	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
344609007035	G1 box; other site
344609007036	GTP/Mg2+ binding site [chemical binding]; other site
344609007037	G2 box; other site
344609007038	Switch I region; other site
344609007039	G3 box; other site
344609007040	Switch II region; other site
344609007041	G4 box; other site
344609007042	G5 box; other site
344609007043	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
344609007044	putative hexamer interface [polypeptide binding]; other site
344609007045	putative hexagonal pore; other site
344609007046	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
344609007047	Malic enzyme, N-terminal domain; Region: malic; pfam00390
344609007048	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
344609007049	putative NAD(P) binding site [chemical binding]; other site
344609007050	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
344609007051	transaldolase-like protein; Provisional; Region: PTZ00411
344609007052	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
344609007053	active site
344609007054	dimer interface [polypeptide binding]; other site
344609007055	catalytic residue [active]
344609007056	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
344609007057	TPP-binding site [chemical binding]; other site
344609007058	dimer interface [polypeptide binding]; other site
344609007059	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609007060	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609007061	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609007062	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
344609007063	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
344609007064	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
344609007065	dimer interface [polypeptide binding]; other site
344609007066	ADP-ribose binding site [chemical binding]; other site
344609007067	active site
344609007068	nudix motif; other site
344609007069	metal binding site [ion binding]; metal-binding site
344609007070	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
344609007071	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
344609007072	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
344609007073	dimerization interface [polypeptide binding]; other site
344609007074	Histidine kinase; Region: HisKA_3; pfam07730
344609007075	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609007076	ATP binding site [chemical binding]; other site
344609007077	Mg2+ binding site [ion binding]; other site
344609007078	G-X-G motif; other site
344609007079	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609007080	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
344609007081	ArsC family; Region: ArsC; pfam03960
344609007082	putative catalytic residues [active]
344609007083	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
344609007084	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
344609007085	metal binding site [ion binding]; metal-binding site
344609007086	dimer interface [polypeptide binding]; other site
344609007087	hypothetical protein; Provisional; Region: PRK13664
344609007088	putative hydrolase; Provisional; Region: PRK11460
344609007089	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
344609007090	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
344609007091	Helicase; Region: Helicase_RecD; pfam05127
344609007092	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
344609007093	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
344609007094	Predicted metalloprotease [General function prediction only]; Region: COG2321
344609007095	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
344609007096	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
344609007097	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
344609007098	ATP binding site [chemical binding]; other site
344609007099	active site
344609007100	substrate binding site [chemical binding]; other site
344609007101	lipoprotein; Provisional; Region: PRK11679
344609007102	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
344609007103	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
344609007104	dihydrodipicolinate synthase; Region: dapA; TIGR00674
344609007105	dimer interface [polypeptide binding]; other site
344609007106	active site
344609007107	catalytic residue [active]
344609007108	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
344609007109	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
344609007110	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
344609007111	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
344609007112	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
344609007113	catalytic triad [active]
344609007114	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
344609007115	4Fe-4S binding domain; Region: Fer4; pfam00037
344609007116	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
344609007117	NADH dehydrogenase; Region: NADHdh; cl00469
344609007118	hydrogenase 4 membrane subunit; Provisional; Region: hyfE; PRK11492
344609007119	hydrogenase 4 subunit F; Validated; Region: PRK06458
344609007120	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
344609007121	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
344609007122	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
344609007123	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
344609007124	hydrogenase 4 subunit H; Validated; Region: PRK08222
344609007125	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
344609007126	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
344609007127	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
344609007128	Formate/nitrite transporter; Region: Form_Nir_trans; cl00927
344609007129	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609007130	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609007131	Formate/nitrite transporter; Region: Form_Nir_trans; cl00927
344609007132	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
344609007133	Domain of unknown function DUF20; Region: UPF0118; pfam01594
344609007134	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
344609007135	Peptidase family M48; Region: Peptidase_M48; cl12018
344609007136	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
344609007137	ArsC family; Region: ArsC; pfam03960
344609007138	catalytic residues [active]
344609007139	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
344609007140	DNA replication initiation factor; Provisional; Region: PRK08084
344609007141	uracil transporter; Provisional; Region: PRK10720
344609007142	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
344609007143	active site
344609007144	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
344609007145	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
344609007146	dimerization interface [polypeptide binding]; other site
344609007147	putative ATP binding site [chemical binding]; other site
344609007148	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
344609007149	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
344609007150	active site
344609007151	substrate binding site [chemical binding]; other site
344609007152	cosubstrate binding site; other site
344609007153	catalytic site [active]
344609007154	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
344609007155	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
344609007156	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
344609007157	Catalytic C-terminal domain, first repeat, of prokaryotic polyphosphate kinase 1 and similar proteins; Region: PLDc_PPK1_C1; cd09114
344609007158	domain interface [polypeptide binding]; other site
344609007159	active site
344609007160	catalytic site [active]
344609007161	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
344609007162	putative active site [active]
344609007163	catalytic site [active]
344609007164	exopolyphosphatase; Provisional; Region: PRK10854
344609007165	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
344609007166	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609007167	GMP synthase; Reviewed; Region: guaA; PRK00074
344609007168	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
344609007169	AMP/PPi binding site [chemical binding]; other site
344609007170	candidate oxyanion hole; other site
344609007171	catalytic triad [active]
344609007172	potential glutamine specificity residues [chemical binding]; other site
344609007173	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
344609007174	ATP Binding subdomain [chemical binding]; other site
344609007175	Ligand Binding sites [chemical binding]; other site
344609007176	Dimerization subdomain; other site
344609007177	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
344609007178	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
344609007179	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
344609007180	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
344609007181	active site
344609007182	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
344609007183	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
344609007184	generic binding surface II; other site
344609007185	generic binding surface I; other site
344609007186	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
344609007187	GTP-binding protein Der; Reviewed; Region: PRK00093
344609007188	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
344609007189	G1 box; other site
344609007190	GTP/Mg2+ binding site [chemical binding]; other site
344609007191	Switch I region; other site
344609007192	G2 box; other site
344609007193	Switch II region; other site
344609007194	G3 box; other site
344609007195	G4 box; other site
344609007196	G5 box; other site
344609007197	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
344609007198	G1 box; other site
344609007199	GTP/Mg2+ binding site [chemical binding]; other site
344609007200	Switch I region; other site
344609007201	G2 box; other site
344609007202	G3 box; other site
344609007203	Switch II region; other site
344609007204	G4 box; other site
344609007205	G5 box; other site
344609007206	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
344609007207	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cd00216
344609007208	Trp docking motif [polypeptide binding]; other site
344609007209	active site
344609007210	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
344609007211	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
344609007212	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
344609007213	dimer interface [polypeptide binding]; other site
344609007214	motif 1; other site
344609007215	active site
344609007216	motif 2; other site
344609007217	motif 3; other site
344609007218	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
344609007219	anticodon binding site; other site
344609007220	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
344609007221	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
344609007222	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
344609007223	cytoskeletal protein RodZ; Provisional; Region: PRK10856
344609007224	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
344609007225	non-specific DNA binding site [nucleotide binding]; other site
344609007226	salt bridge; other site
344609007227	sequence-specific DNA binding site [nucleotide binding]; other site
344609007228	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
344609007229	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
344609007230	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
344609007231	FeS/SAM binding site; other site
344609007232	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
344609007233	active site
344609007234	multimer interface [polypeptide binding]; other site
344609007235	penicillin-binding protein 1C; Provisional; Region: PRK11240
344609007236	Transglycosylase; Region: Transgly; pfam00912
344609007237	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
344609007238	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
344609007239	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
344609007240	MG2 domain; Region: A2M_N; pfam01835
344609007241	Alpha-2-macroglobulin family; Region: A2M; pfam00207
344609007242	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
344609007243	surface patch; other site
344609007244	thioester region; other site
344609007245	specificity defining residues; other site
344609007246	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
344609007247	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
344609007248	active site residue [active]
344609007249	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
344609007250	active site residue [active]
344609007251	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
344609007252	aminopeptidase B; Provisional; Region: PRK05015
344609007253	Peptidase; Region: DUF3663; pfam12404
344609007254	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
344609007255	interface (dimer of trimers) [polypeptide binding]; other site
344609007256	Substrate-binding/catalytic site; other site
344609007257	Zn-binding sites [ion binding]; other site
344609007258	hypothetical protein; Provisional; Region: PRK10721
344609007259	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
344609007260	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
344609007261	catalytic loop [active]
344609007262	iron binding site [ion binding]; other site
344609007263	chaperone protein HscA; Provisional; Region: hscA; PRK05183
344609007264	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
344609007265	nucleotide binding site [chemical binding]; other site
344609007266	putative NEF/HSP70 interaction site [polypeptide binding]; other site
344609007267	SBD interface [polypeptide binding]; other site
344609007268	co-chaperone HscB; Provisional; Region: hscB; PRK05014
344609007269	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
344609007270	HSP70 interaction site [polypeptide binding]; other site
344609007271	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
344609007272	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
344609007273	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
344609007274	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
344609007275	trimerization site [polypeptide binding]; other site
344609007276	active site
344609007277	cysteine desulfurase; Provisional; Region: PRK14012
344609007278	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
344609007279	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
344609007280	catalytic residue [active]
344609007281	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
344609007282	Rrf2 family protein; Region: rrf2_super; TIGR00738
344609007283	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
344609007284	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
344609007285	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
344609007286	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
344609007287	active site
344609007288	dimerization interface [polypeptide binding]; other site
344609007289	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
344609007290	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
344609007291	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
344609007292	PRD domain; Region: PRD; pfam00874
344609007293	PRD domain; Region: PRD; pfam00874
344609007294	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
344609007295	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609007296	putative substrate translocation pore; other site
344609007297	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
344609007298	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609007299	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
344609007300	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
344609007301	dimer interface [polypeptide binding]; other site
344609007302	active site
344609007303	glycine-pyridoxal phosphate binding site [chemical binding]; other site
344609007304	folate binding site [chemical binding]; other site
344609007305	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
344609007306	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
344609007307	heme-binding site [chemical binding]; other site
344609007308	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
344609007309	FAD binding pocket [chemical binding]; other site
344609007310	FAD binding motif [chemical binding]; other site
344609007311	phosphate binding motif [ion binding]; other site
344609007312	beta-alpha-beta structure motif; other site
344609007313	NAD binding pocket [chemical binding]; other site
344609007314	Heme binding  pocket [chemical binding]; other site
344609007315	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
344609007316	Nitrogen regulatory protein P-II; Region: P-II; smart00938
344609007317	response regulator GlrR; Provisional; Region: PRK15115
344609007318	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609007319	active site
344609007320	phosphorylation site [posttranslational modification]
344609007321	intermolecular recognition site; other site
344609007322	dimerization interface [polypeptide binding]; other site
344609007323	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609007324	Walker A motif; other site
344609007325	ATP binding site [chemical binding]; other site
344609007326	Walker B motif; other site
344609007327	arginine finger; other site
344609007328	hypothetical protein; Provisional; Region: PRK10722
344609007329	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
344609007330	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609007331	dimer interface [polypeptide binding]; other site
344609007332	phosphorylation site [posttranslational modification]
344609007333	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609007334	ATP binding site [chemical binding]; other site
344609007335	Mg2+ binding site [ion binding]; other site
344609007336	G-X-G motif; other site
344609007337	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
344609007338	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
344609007339	dimerization interface [polypeptide binding]; other site
344609007340	ATP binding site [chemical binding]; other site
344609007341	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
344609007342	dimerization interface [polypeptide binding]; other site
344609007343	ATP binding site [chemical binding]; other site
344609007344	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
344609007345	putative active site [active]
344609007346	catalytic triad [active]
344609007347	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
344609007348	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
344609007349	substrate binding pocket [chemical binding]; other site
344609007350	membrane-bound complex binding site; other site
344609007351	hinge residues; other site
344609007352	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
344609007353	N-acetyl-D-glucosamine binding site [chemical binding]; other site
344609007354	catalytic residue [active]
344609007355	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
344609007356	nucleoside/Zn binding site; other site
344609007357	dimer interface [polypeptide binding]; other site
344609007358	catalytic motif [active]
344609007359	hypothetical protein; Provisional; Region: PRK11590
344609007360	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
344609007361	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
344609007362	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
344609007363	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
344609007364	putative active site [active]
344609007365	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
344609007366	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
344609007367	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
344609007368	active site
344609007369	hydrophilic channel; other site
344609007370	dimerization interface [polypeptide binding]; other site
344609007371	catalytic residues [active]
344609007372	active site lid [active]
344609007373	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
344609007374	Recombination protein O N terminal; Region: RecO_N; pfam11967
344609007375	Recombination protein O C terminal; Region: RecO_C; pfam02565
344609007376	GTPase Era; Reviewed; Region: era; PRK00089
344609007377	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
344609007378	G1 box; other site
344609007379	GTP/Mg2+ binding site [chemical binding]; other site
344609007380	Switch I region; other site
344609007381	G2 box; other site
344609007382	Switch II region; other site
344609007383	G3 box; other site
344609007384	G4 box; other site
344609007385	G5 box; other site
344609007386	KH domain; Region: KH_2; pfam07650
344609007387	ribonuclease III; Reviewed; Region: rnc; PRK00102
344609007388	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
344609007389	dimerization interface [polypeptide binding]; other site
344609007390	active site
344609007391	metal binding site [ion binding]; metal-binding site
344609007392	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
344609007393	dsRNA binding site [nucleotide binding]; other site
344609007394	rncO
344609007395	signal peptidase I; Provisional; Region: PRK10861
344609007396	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
344609007397	Catalytic site [active]
344609007398	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
344609007399	GTP-binding protein LepA; Provisional; Region: PRK05433
344609007400	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
344609007401	G1 box; other site
344609007402	putative GEF interaction site [polypeptide binding]; other site
344609007403	GTP/Mg2+ binding site [chemical binding]; other site
344609007404	Switch I region; other site
344609007405	G2 box; other site
344609007406	G3 box; other site
344609007407	Switch II region; other site
344609007408	G4 box; other site
344609007409	G5 box; other site
344609007410	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
344609007411	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
344609007412	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
344609007413	SoxR reducing system protein RseC; Provisional; Region: PRK10862
344609007414	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
344609007415	anti-sigma E factor; Provisional; Region: rseB; PRK09455
344609007416	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
344609007417	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
344609007418	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
344609007419	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
344609007420	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
344609007421	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
344609007422	DNA binding residues [nucleotide binding]
344609007423	L-aspartate oxidase; Provisional; Region: PRK06175
344609007424	putative transposase OrfB; Reviewed; Region: PHA02517
344609007425	Integrase core domain; Region: rve; pfam00665
344609007426	Integrase core domain; Region: rve_3; pfam13683
344609007427	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609007428	Transposase; Region: HTH_Tnp_1; pfam01527
344609007429	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
344609007430	Methyltransferase domain; Region: Methyltransf_26; pfam13659
344609007431	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
344609007432	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
344609007433	ATP binding site [chemical binding]; other site
344609007434	Mg++ binding site [ion binding]; other site
344609007435	motif III; other site
344609007436	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
344609007437	nucleotide binding region [chemical binding]; other site
344609007438	ATP-binding site [chemical binding]; other site
344609007439	Transcriptional regulator [Transcription]; Region: LysR; COG0583
344609007440	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
344609007441	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609007442	HTH-like domain; Region: HTH_21; pfam13276
344609007443	Integrase core domain; Region: rve; pfam00665
344609007444	Integrase core domain; Region: rve_3; pfam13683
344609007445	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609007446	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609007447	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609007448	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609007449	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609007450	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609007451	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609007452	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
344609007453	lipoprotein; Provisional; Region: PRK10759
344609007454	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
344609007455	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
344609007456	domain interface [polypeptide binding]; other site
344609007457	putative active site [active]
344609007458	catalytic site [active]
344609007459	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
344609007460	domain interface [polypeptide binding]; other site
344609007461	putative active site [active]
344609007462	catalytic site [active]
344609007463	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
344609007464	CoA binding domain; Region: CoA_binding_2; pfam13380
344609007465	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
344609007466	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
344609007467	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
344609007468	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
344609007469	Uncharacterized conserved protein [Function unknown]; Region: COG3148
344609007470	thioredoxin 2; Provisional; Region: PRK10996
344609007471	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
344609007472	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
344609007473	catalytic residues [active]
344609007474	putative methyltransferase; Provisional; Region: PRK10864
344609007475	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
344609007476	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
344609007477	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
344609007478	ligand binding site [chemical binding]; other site
344609007479	active site
344609007480	UGI interface [polypeptide binding]; other site
344609007481	catalytic site [active]
344609007482	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
344609007483	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
344609007484	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609007485	HTH-like domain; Region: HTH_21; pfam13276
344609007486	Integrase core domain; Region: rve; pfam00665
344609007487	Integrase core domain; Region: rve_3; pfam13683
344609007488	Transcriptional regulator [Transcription]; Region: LysR; COG0583
344609007489	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609007490	LysR substrate binding domain; Region: LysR_substrate; pfam03466
344609007491	dimerization interface [polypeptide binding]; other site
344609007492	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609007493	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609007494	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609007495	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609007496	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609007497	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609007498	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609007499	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609007500	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609007501	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609007502	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609007503	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609007504	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609007505	putative substrate translocation pore; other site
344609007506	protein disaggregation chaperone; Provisional; Region: PRK10865
344609007507	Clp amino terminal domain; Region: Clp_N; pfam02861
344609007508	Clp amino terminal domain; Region: Clp_N; pfam02861
344609007509	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609007510	Walker A motif; other site
344609007511	ATP binding site [chemical binding]; other site
344609007512	Walker B motif; other site
344609007513	arginine finger; other site
344609007514	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609007515	Walker A motif; other site
344609007516	ATP binding site [chemical binding]; other site
344609007517	Walker B motif; other site
344609007518	arginine finger; other site
344609007519	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
344609007520	hypothetical protein; Provisional; Region: PRK10723
344609007521	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
344609007522	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
344609007523	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
344609007524	RNA binding surface [nucleotide binding]; other site
344609007525	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
344609007526	active site
344609007527	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
344609007528	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
344609007529	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609007530	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609007531	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609007532	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609007533	Transposase; Region: HTH_Tnp_1; pfam01527
344609007534	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
344609007535	30S subunit binding site; other site
344609007536	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
344609007537	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
344609007538	Prephenate dehydratase; Region: PDT; pfam00800
344609007539	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
344609007540	putative L-Phe binding site [chemical binding]; other site
344609007541	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
344609007542	chorismate mutase domain of T-protein; Region: CM_T; TIGR01799
344609007543	prephenate dehydrogenase; Validated; Region: PRK08507
344609007544	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
344609007545	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
344609007546	lipoprotein; Provisional; Region: PRK11443
344609007547	Protein of unknown function (DUF2799); Region: DUF2799; pfam10973
344609007548	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
344609007549	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609007550	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
344609007551	metal binding site [ion binding]; metal-binding site
344609007552	active site
344609007553	I-site; other site
344609007554	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
344609007555	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
344609007556	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
344609007557	RimM N-terminal domain; Region: RimM; pfam01782
344609007558	PRC-barrel domain; Region: PRC; pfam05239
344609007559	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
344609007560	signal recognition particle protein; Provisional; Region: PRK10867
344609007561	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
344609007562	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
344609007563	P loop; other site
344609007564	GTP binding site [chemical binding]; other site
344609007565	Signal peptide binding domain; Region: SRP_SPB; pfam02978
344609007566	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
344609007567	hypothetical protein; Provisional; Region: PRK11573
344609007568	Domain of unknown function DUF21; Region: DUF21; pfam01595
344609007569	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
344609007570	Transporter associated domain; Region: CorC_HlyC; smart01091
344609007571	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
344609007572	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
344609007573	dimer interface [polypeptide binding]; other site
344609007574	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
344609007575	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
344609007576	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
344609007577	recombination and repair protein; Provisional; Region: PRK10869
344609007578	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
344609007579	Walker A/P-loop; other site
344609007580	ATP binding site [chemical binding]; other site
344609007581	Q-loop/lid; other site
344609007582	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
344609007583	Q-loop/lid; other site
344609007584	ABC transporter signature motif; other site
344609007585	Walker B; other site
344609007586	D-loop; other site
344609007587	H-loop/switch region; other site
344609007588	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
344609007589	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
344609007590	hypothetical protein; Validated; Region: PRK01777
344609007591	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
344609007592	putative coenzyme Q binding site [chemical binding]; other site
344609007593	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
344609007594	SmpB-tmRNA interface; other site
344609007595	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609007596	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
344609007597	serine transporter; Region: stp; TIGR00814
344609007598	putative acyltransferase; Provisional; Region: PRK05790
344609007599	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
344609007600	dimer interface [polypeptide binding]; other site
344609007601	active site
344609007602	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
344609007603	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609007604	Transposase; Region: HTH_Tnp_1; pfam01527
344609007605	2-deoxy-D-gluconate 3-dehydrogenase; Region: kduD; TIGR01832
344609007606	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
344609007607	NADP binding site [chemical binding]; other site
344609007608	homodimer interface [polypeptide binding]; other site
344609007609	active site
344609007610	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
344609007611	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609007612	putative substrate translocation pore; other site
344609007613	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609007614	putative racemase; Provisional; Region: PRK10200
344609007615	aspartate racemase; Region: asp_race; TIGR00035
344609007616	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
344609007617	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609007618	The C-terminal substrate binding domain of LysR, transcriptional regulator for lysine biosynthesis, contains the type 2 periplasmic binding fold; Region: PBP2_LysR; cd08456
344609007619	putative dimerization interface [polypeptide binding]; other site
344609007620	diaminopimelate decarboxylase; Provisional; Region: PRK11165
344609007621	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
344609007622	active site
344609007623	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
344609007624	substrate binding site [chemical binding]; other site
344609007625	catalytic residues [active]
344609007626	dimer interface [polypeptide binding]; other site
344609007627	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
344609007628	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
344609007629	DNA binding site [nucleotide binding]
344609007630	domain linker motif; other site
344609007631	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
344609007632	dimerization interface (closed form) [polypeptide binding]; other site
344609007633	ligand binding site [chemical binding]; other site
344609007634	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
344609007635	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
344609007636	putative acyl-acceptor binding pocket; other site
344609007637	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
344609007638	acyl-activating enzyme (AAE) consensus motif; other site
344609007639	putative AMP binding site [chemical binding]; other site
344609007640	lysophospholipid transporter LplT; Provisional; Region: PRK11195
344609007641	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609007642	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
344609007643	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
344609007644	active site
344609007645	catalytic tetrad [active]
344609007646	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
344609007647	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
344609007648	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
344609007649	putative DNA-binding cleft [nucleotide binding]; other site
344609007650	putative DNA clevage site; other site
344609007651	molecular lever; other site
344609007652	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
344609007653	putative active site [active]
344609007654	Ap4A binding site [chemical binding]; other site
344609007655	nudix motif; other site
344609007656	putative metal binding site [ion binding]; other site
344609007657	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
344609007658	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
344609007659	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
344609007660	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
344609007661	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
344609007662	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
344609007663	thymidylate synthase; Reviewed; Region: thyA; PRK01827
344609007664	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
344609007665	dimerization interface [polypeptide binding]; other site
344609007666	active site
344609007667	hypothetical protein; Provisional; Region: PRK10506
344609007668	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
344609007669	hypothetical protein; Provisional; Region: PRK10557
344609007670	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
344609007671	hypothetical protein; Provisional; Region: PRK11521
344609007672	hypothetical protein; Provisional; Region: PRK10332
344609007673	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
344609007674	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
344609007675	exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450
344609007676	protease3; Provisional; Region: PRK15101
344609007677	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
344609007678	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
344609007679	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
344609007680	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
344609007681	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
344609007682	AAA domain; Region: AAA_30; pfam13604
344609007683	Family description; Region: UvrD_C_2; pfam13538
344609007684	N-acetylglutamate synthase; Validated; Region: PRK05279
344609007685	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
344609007686	putative feedback inhibition sensing region; other site
344609007687	putative nucleotide binding site [chemical binding]; other site
344609007688	putative substrate binding site [chemical binding]; other site
344609007689	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
344609007690	Coenzyme A binding pocket [chemical binding]; other site
344609007691	AMIN domain; Region: AMIN; pfam11741
344609007692	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
344609007693	active site
344609007694	metal binding site [ion binding]; metal-binding site
344609007695	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
344609007696	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609007697	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
344609007698	Putative D-3-Phosphoglycerate Dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_like_2; cd12172
344609007699	putative ligand binding site [chemical binding]; other site
344609007700	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
344609007701	putative NAD binding site [chemical binding]; other site
344609007702	catalytic site [active]
344609007703	murein transglycosylase A; Provisional; Region: mltA; PRK11162
344609007704	MltA specific insert domain; Region: MltA; pfam03562
344609007705	3D domain; Region: 3D; pfam06725
344609007706	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
344609007707	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
344609007708	putative ATP binding site [chemical binding]; other site
344609007709	putative substrate interface [chemical binding]; other site
344609007710	CsdA-binding activator; Provisional; Region: PRK15019
344609007711	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
344609007712	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
344609007713	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
344609007714	catalytic residue [active]
344609007715	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
344609007716	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
344609007717	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609007718	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
344609007719	dimerization interface [polypeptide binding]; other site
344609007720	substrate binding pocket [chemical binding]; other site
344609007721	hypothetical protein; Provisional; Region: PRK10873
344609007722	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
344609007723	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
344609007724	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
344609007725	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
344609007726	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609007727	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
344609007728	active site
344609007729	Zn2+ binding site [ion binding]; other site
344609007730	intersubunit interface [polypeptide binding]; other site
344609007731	flap endonuclease-like protein; Provisional; Region: PRK09482
344609007732	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
344609007733	active site
344609007734	metal binding site 1 [ion binding]; metal-binding site
344609007735	putative 5' ssDNA interaction site; other site
344609007736	metal binding site 3; metal-binding site
344609007737	metal binding site 2 [ion binding]; metal-binding site
344609007738	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
344609007739	putative DNA binding site [nucleotide binding]; other site
344609007740	putative metal binding site [ion binding]; other site
344609007741	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
344609007742	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
344609007743	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
344609007744	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
344609007745	serine transporter; Region: stp; TIGR00814
344609007746	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
344609007747	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
344609007748	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
344609007749	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
344609007750	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
344609007751	SecY interacting protein Syd; Provisional; Region: PRK04968
344609007752	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
344609007753	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
344609007754	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
344609007755	probable active site [active]
344609007756	flavodoxin; Provisional; Region: PRK08105
344609007757	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609007758	D-galactonate transporter; Region: 2A0114; TIGR00893
344609007759	putative substrate translocation pore; other site
344609007760	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
344609007761	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
344609007762	active site
344609007763	tetramer interface [polypeptide binding]; other site
344609007764	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
344609007765	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
344609007766	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
344609007767	dimerization interface [polypeptide binding]; other site
344609007768	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609007769	dimer interface [polypeptide binding]; other site
344609007770	phosphorylation site [posttranslational modification]
344609007771	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609007772	ATP binding site [chemical binding]; other site
344609007773	Mg2+ binding site [ion binding]; other site
344609007774	G-X-G motif; other site
344609007775	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
344609007776	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609007777	active site
344609007778	phosphorylation site [posttranslational modification]
344609007779	intermolecular recognition site; other site
344609007780	dimerization interface [polypeptide binding]; other site
344609007781	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
344609007782	putative binding surface; other site
344609007783	active site
344609007784	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
344609007785	TRAM domain; Region: TRAM; pfam01938
344609007786	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609007787	S-adenosylmethionine binding site [chemical binding]; other site
344609007788	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
344609007789	HD domain; Region: HD_4; pfam13328
344609007790	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
344609007791	synthetase active site [active]
344609007792	NTP binding site [chemical binding]; other site
344609007793	metal binding site [ion binding]; metal-binding site
344609007794	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
344609007795	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
344609007796	antitoxin MazE; Provisional; Region: PRK09798
344609007797	toxin MazF; Provisional; Region: PRK09907
344609007798	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
344609007799	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
344609007800	homodimer interface [polypeptide binding]; other site
344609007801	metal binding site [ion binding]; metal-binding site
344609007802	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
344609007803	homodimer interface [polypeptide binding]; other site
344609007804	active site
344609007805	putative chemical substrate binding site [chemical binding]; other site
344609007806	metal binding site [ion binding]; metal-binding site
344609007807	CTP synthetase; Validated; Region: pyrG; PRK05380
344609007808	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
344609007809	Catalytic site [active]
344609007810	active site
344609007811	UTP binding site [chemical binding]; other site
344609007812	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
344609007813	active site
344609007814	putative oxyanion hole; other site
344609007815	catalytic triad [active]
344609007816	enolase; Provisional; Region: eno; PRK00077
344609007817	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
344609007818	dimer interface [polypeptide binding]; other site
344609007819	metal binding site [ion binding]; metal-binding site
344609007820	substrate binding pocket [chemical binding]; other site
344609007821	Repair protein; Region: Repair_PSII; pfam04536
344609007822	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609007823	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609007824	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609007825	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609007826	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609007827	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609007828	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609007829	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
344609007830	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
344609007831	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609007832	benzoate transport; Region: 2A0115; TIGR00895
344609007833	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609007834	putative substrate translocation pore; other site
344609007835	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
344609007836	Ligand binding site [chemical binding]; other site
344609007837	Electron transfer flavoprotein domain; Region: ETF; pfam01012
344609007838	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
344609007839	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
344609007840	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
344609007841	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
344609007842	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
344609007843	oxidoreductase; Provisional; Region: PRK10015
344609007844	6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a...; Region: PTPS; cd00470
344609007845	homohexamer interface [polypeptide binding]; other site
344609007846	putative substrate stabilizing pore; other site
344609007847	pterin binding site; other site
344609007848	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609007849	Transposase; Region: HTH_Tnp_1; cl17663
344609007850	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
344609007851	Flavodoxin; Region: Flavodoxin_1; pfam00258
344609007852	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
344609007853	FAD binding pocket [chemical binding]; other site
344609007854	FAD binding motif [chemical binding]; other site
344609007855	catalytic residues [active]
344609007856	NAD binding pocket [chemical binding]; other site
344609007857	phosphate binding motif [ion binding]; other site
344609007858	beta-alpha-beta structure motif; other site
344609007859	sulfite reductase subunit beta; Provisional; Region: PRK13504
344609007860	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
344609007861	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
344609007862	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
344609007863	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
344609007864	Active Sites [active]
344609007865	Hok/gef family; Region: HOK_GEF; pfam01848
344609007866	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609007867	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
344609007868	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
344609007869	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09664
344609007870	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09648
344609007871	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
344609007872	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
344609007873	metal binding site [ion binding]; metal-binding site
344609007874	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
344609007875	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
344609007876	Active Sites [active]
344609007877	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
344609007878	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
344609007879	CysD dimerization site [polypeptide binding]; other site
344609007880	G1 box; other site
344609007881	putative GEF interaction site [polypeptide binding]; other site
344609007882	GTP/Mg2+ binding site [chemical binding]; other site
344609007883	Switch I region; other site
344609007884	G2 box; other site
344609007885	G3 box; other site
344609007886	Switch II region; other site
344609007887	G4 box; other site
344609007888	G5 box; other site
344609007889	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
344609007890	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
344609007891	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
344609007892	ligand-binding site [chemical binding]; other site
344609007893	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
344609007894	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
344609007895	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
344609007896	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
344609007897	substrate binding site; other site
344609007898	dimer interface; other site
344609007899	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
344609007900	homotrimer interaction site [polypeptide binding]; other site
344609007901	zinc binding site [ion binding]; other site
344609007902	CDP-binding sites; other site
344609007903	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
344609007904	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
344609007905	Permutation of conserved domain; other site
344609007906	active site
344609007907	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
344609007908	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
344609007909	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609007910	S-adenosylmethionine binding site [chemical binding]; other site
344609007911	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
344609007912	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
344609007913	Peptidase family M23; Region: Peptidase_M23; pfam01551
344609007914	putative transporter; Provisional; Region: PRK09821
344609007915	GntP family permease; Region: GntP_permease; pfam02447
344609007916	hypothetical protein; Provisional; Region: PRK09989
344609007917	putative aldolase; Validated; Region: PRK08130
344609007918	active site
344609007919	intersubunit interface [polypeptide binding]; other site
344609007920	Zn2+ binding site [ion binding]; other site
344609007921	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
344609007922	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
344609007923	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
344609007924	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
344609007925	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
344609007926	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609007927	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
344609007928	MutS domain I; Region: MutS_I; pfam01624
344609007929	MutS domain II; Region: MutS_II; pfam05188
344609007930	MutS domain III; Region: MutS_III; pfam05192
344609007931	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
344609007932	Walker A/P-loop; other site
344609007933	ATP binding site [chemical binding]; other site
344609007934	Q-loop/lid; other site
344609007935	ABC transporter signature motif; other site
344609007936	Walker B; other site
344609007937	D-loop; other site
344609007938	H-loop/switch region; other site
344609007939	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
344609007940	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
344609007941	dimerization interface [polypeptide binding]; other site
344609007942	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
344609007943	ATP binding site [chemical binding]; other site
344609007944	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
344609007945	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
344609007946	hydrogenase assembly chaperone; Provisional; Region: PRK10409
344609007947	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
344609007948	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
344609007949	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
344609007950	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
344609007951	NADH dehydrogenase; Region: NADHdh; cl00469
344609007952	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
344609007953	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
344609007954	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
344609007955	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
344609007956	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
344609007957	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
344609007958	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
344609007959	nickel binding site [ion binding]; other site
344609007960	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
344609007961	beta-galactosidase; Region: BGL; TIGR03356
344609007962	Transcriptional regulators [Transcription]; Region: PurR; COG1609
344609007963	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
344609007964	DNA binding site [nucleotide binding]
344609007965	domain linker motif; other site
344609007966	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
344609007967	dimerization interface (closed form) [polypeptide binding]; other site
344609007968	ligand binding site [chemical binding]; other site
344609007969	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
344609007970	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
344609007971	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
344609007972	Acylphosphatase; Region: Acylphosphatase; pfam00708
344609007973	HypF finger; Region: zf-HYPF; pfam07503
344609007974	HypF finger; Region: zf-HYPF; pfam07503
344609007975	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
344609007976	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
344609007977	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
344609007978	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
344609007979	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
344609007980	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
344609007981	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
344609007982	iron binding site [ion binding]; other site
344609007983	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
344609007984	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
344609007985	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609007986	Walker A motif; other site
344609007987	ATP binding site [chemical binding]; other site
344609007988	Walker B motif; other site
344609007989	arginine finger; other site
344609007990	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
344609007991	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
344609007992	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
344609007993	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
344609007994	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
344609007995	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
344609007996	putative NAD(P) binding site [chemical binding]; other site
344609007997	active site
344609007998	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
344609007999	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
344609008000	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
344609008001	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
344609008002	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
344609008003	Transglycosylase SLT domain; Region: SLT_2; pfam13406
344609008004	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
344609008005	N-acetyl-D-glucosamine binding site [chemical binding]; other site
344609008006	hypothetical protein; Validated; Region: PRK03661
344609008007	recombinase A; Provisional; Region: recA; PRK09354
344609008008	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
344609008009	hexamer interface [polypeptide binding]; other site
344609008010	Walker A motif; other site
344609008011	ATP binding site [chemical binding]; other site
344609008012	Walker B motif; other site
344609008013	recombination regulator RecX; Reviewed; Region: recX; PRK00117
344609008014	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
344609008015	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
344609008016	motif 1; other site
344609008017	active site
344609008018	motif 2; other site
344609008019	motif 3; other site
344609008020	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
344609008021	DHHA1 domain; Region: DHHA1; pfam02272
344609008022	carbon storage regulator; Provisional; Region: PRK01712
344609008023	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
344609008024	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609008025	motif II; other site
344609008026	Predicted membrane protein [Function unknown]; Region: COG1238
344609008027	glutamate--cysteine ligase; Provisional; Region: PRK02107
344609008028	S-ribosylhomocysteinase; Provisional; Region: PRK02260
344609008029	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
344609008030	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609008031	putative substrate translocation pore; other site
344609008032	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609008033	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
344609008034	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
344609008035	HlyD family secretion protein; Region: HlyD_3; pfam13437
344609008036	transcriptional repressor MprA; Provisional; Region: PRK10870
344609008037	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
344609008038	putative L-valine exporter; Provisional; Region: PRK10408
344609008039	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
344609008040	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008041	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
344609008042	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609008043	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
344609008044	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
344609008045	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
344609008046	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609008047	dimer interface [polypeptide binding]; other site
344609008048	conserved gate region; other site
344609008049	putative PBP binding loops; other site
344609008050	ABC-ATPase subunit interface; other site
344609008051	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
344609008052	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
344609008053	Walker A/P-loop; other site
344609008054	ATP binding site [chemical binding]; other site
344609008055	Q-loop/lid; other site
344609008056	ABC transporter signature motif; other site
344609008057	Walker B; other site
344609008058	D-loop; other site
344609008059	H-loop/switch region; other site
344609008060	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
344609008061	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
344609008062	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
344609008063	dimer interface [polypeptide binding]; other site
344609008064	putative radical transfer pathway; other site
344609008065	diiron center [ion binding]; other site
344609008066	tyrosyl radical; other site
344609008067	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
344609008068	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
344609008069	Class I ribonucleotide reductase; Region: RNR_I; cd01679
344609008070	active site
344609008071	dimer interface [polypeptide binding]; other site
344609008072	catalytic residues [active]
344609008073	effector binding site; other site
344609008074	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
344609008075	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
344609008076	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
344609008077	catalytic residues [active]
344609008078	hypothetical protein; Provisional; Region: PRK10132
344609008079	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008080	hypothetical protein; Provisional; Region: PRK10556
344609008081	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
344609008082	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
344609008083	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
344609008084	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YgaP, and similar uncharacterized putative rhodanese-related sulfurtransferases; Region: RHOD_YgaP; cd01527
344609008085	active site residue [active]
344609008086	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
344609008087	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
344609008088	dimerization interface [polypeptide binding]; other site
344609008089	putative DNA binding site [nucleotide binding]; other site
344609008090	Transcriptional regulators [Transcription]; Region: MarR; COG1846
344609008091	putative Zn2+ binding site [ion binding]; other site
344609008092	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
344609008093	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
344609008094	bacterial OsmY and nodulation domain; Region: BON; smart00749
344609008095	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
344609008096	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
344609008097	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
344609008098	DNA-binding site [nucleotide binding]; DNA binding site
344609008099	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
344609008100	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
344609008101	Predicted dehydrogenase [General function prediction only]; Region: COG0579
344609008102	hydroxyglutarate oxidase; Provisional; Region: PRK11728
344609008103	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
344609008104	substrate binding pocket [chemical binding]; other site
344609008105	active site
344609008106	iron coordination sites [ion binding]; other site
344609008107	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; cl02706
344609008108	IS2 repressor TnpA; Reviewed; Region: PRK09413
344609008109	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609008110	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609008111	HTH-like domain; Region: HTH_21; pfam13276
344609008112	Integrase core domain; Region: rve; pfam00665
344609008113	Integrase core domain; Region: rve_3; pfam13683
344609008114	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008115	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008116	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
344609008117	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
344609008118	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
344609008119	glycerate kinase I; Provisional; Region: PRK10342
344609008120	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008121	DNA-binding transcriptional activator TdcR; Provisional; Region: PRK11424
344609008122	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
344609008123	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609008124	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
344609008125	putative substrate binding pocket [chemical binding]; other site
344609008126	putative dimerization interface [polypeptide binding]; other site
344609008127	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
344609008128	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
344609008129	tetramer interface [polypeptide binding]; other site
344609008130	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609008131	catalytic residue [active]
344609008132	threonine/serine transporter TdcC; Provisional; Region: PRK13629
344609008133	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
344609008134	propionate/acetate kinase; Provisional; Region: PRK12379
344609008135	Acetokinase family; Region: Acetate_kinase; cl17229
344609008136	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
344609008137	Pyruvate formate lyase 1; Region: PFL1; cd01678
344609008138	coenzyme A binding site [chemical binding]; other site
344609008139	active site
344609008140	catalytic residues [active]
344609008141	glycine loop; other site
344609008142	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
344609008143	homotrimer interaction site [polypeptide binding]; other site
344609008144	putative active site [active]
344609008145	L-serine dehydratase TdcG; Provisional; Region: PRK15040
344609008146	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
344609008147	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
344609008148	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008149	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
344609008150	serine transporter; Region: stp; TIGR00814
344609008151	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
344609008152	Pirin-related protein [General function prediction only]; Region: COG1741
344609008153	Pirin; Region: Pirin; pfam02678
344609008154	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008155	Protein of unknown function (DUF805); Region: DUF805; pfam05656
344609008156	Predicted membrane protein [Function unknown]; Region: COG3152
344609008157	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
344609008158	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
344609008159	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
344609008160	putative dimer interface [polypeptide binding]; other site
344609008161	N-terminal domain interface [polypeptide binding]; other site
344609008162	putative substrate binding pocket (H-site) [chemical binding]; other site
344609008163	Predicted membrane protein [Function unknown]; Region: COG2259
344609008164	YqjK-like protein; Region: YqjK; pfam13997
344609008165	Predicted membrane protein [Function unknown]; Region: COG5393
344609008166	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
344609008167	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
344609008168	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
344609008169	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
344609008170	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
344609008171	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
344609008172	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
344609008173	DNA-binding site [nucleotide binding]; DNA binding site
344609008174	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
344609008175	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008176	CS1 type fimbrial major subunit; Region: Fimbrial_CS1; pfam04449
344609008177	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609008178	HTH-like domain; Region: HTH_21; pfam13276
344609008179	Integrase core domain; Region: rve; pfam00665
344609008180	Integrase core domain; Region: rve_3; pfam13683
344609008181	transcriptional regulator; Provisional; Region: PRK10632
344609008182	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609008183	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
344609008184	putative effector binding pocket; other site
344609008185	dimerization interface [polypeptide binding]; other site
344609008186	protease TldD; Provisional; Region: tldD; PRK10735
344609008187	hypothetical protein; Provisional; Region: PRK10899
344609008188	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
344609008189	ribonuclease G; Provisional; Region: PRK11712
344609008190	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
344609008191	homodimer interface [polypeptide binding]; other site
344609008192	oligonucleotide binding site [chemical binding]; other site
344609008193	Maf-like protein; Region: Maf; pfam02545
344609008194	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
344609008195	active site
344609008196	dimer interface [polypeptide binding]; other site
344609008197	rod shape-determining protein MreD; Provisional; Region: PRK11060
344609008198	rod shape-determining protein MreC; Region: mreC; TIGR00219
344609008199	rod shape-determining protein MreC; Region: MreC; pfam04085
344609008200	rod shape-determining protein MreB; Provisional; Region: PRK13927
344609008201	MreB and similar proteins; Region: MreB_like; cd10225
344609008202	nucleotide binding site [chemical binding]; other site
344609008203	Mg binding site [ion binding]; other site
344609008204	putative protofilament interaction site [polypeptide binding]; other site
344609008205	RodZ interaction site [polypeptide binding]; other site
344609008206	regulatory protein CsrD; Provisional; Region: PRK11059
344609008207	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
344609008208	metal binding site [ion binding]; metal-binding site
344609008209	active site
344609008210	I-site; other site
344609008211	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
344609008212	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
344609008213	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
344609008214	NADP binding site [chemical binding]; other site
344609008215	dimer interface [polypeptide binding]; other site
344609008216	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
344609008217	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
344609008218	carboxyltransferase (CT) interaction site; other site
344609008219	biotinylation site [posttranslational modification]; other site
344609008220	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
344609008221	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
344609008222	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
344609008223	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
344609008224	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
344609008225	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
344609008226	substrate binding site [chemical binding]; other site
344609008227	ATP binding site [chemical binding]; other site
344609008228	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
344609008229	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
344609008230	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008231	Nop53 (60S ribosomal biogenesis); Region: Nop53; pfam07767
344609008232	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609008233	Transposase; Region: HTH_Tnp_1; pfam01527
344609008234	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
344609008235	INT_SG2, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 2, C-terminal catalytic domain. The CD contains mainly predicted integrase/recombinases and phage-related integrases. Some have N-terminal domains, which show little sequence...; Region: INT_SG2_C; cd01184
344609008236	Int/Topo IB signature motif; other site
344609008237	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
344609008238	Peptidase family M23; Region: Peptidase_M23; pfam01551
344609008239	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008240	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
344609008241	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
344609008242	active site
344609008243	metal binding site [ion binding]; metal-binding site
344609008244	nudix motif; other site
344609008245	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
344609008246	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
344609008247	dimer interface [polypeptide binding]; other site
344609008248	putative anticodon binding site; other site
344609008249	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
344609008250	motif 1; other site
344609008251	active site
344609008252	motif 2; other site
344609008253	motif 3; other site
344609008254	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
344609008255	DHH family; Region: DHH; pfam01368
344609008256	DHHA1 domain; Region: DHHA1; pfam02272
344609008257	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
344609008258	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
344609008259	dimerization domain [polypeptide binding]; other site
344609008260	dimer interface [polypeptide binding]; other site
344609008261	catalytic residues [active]
344609008262	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
344609008263	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
344609008264	active site
344609008265	Int/Topo IB signature motif; other site
344609008266	flavodoxin FldB; Provisional; Region: PRK12359
344609008267	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
344609008268	hypothetical protein; Provisional; Region: PRK10878
344609008269	putative global regulator; Reviewed; Region: PRK09559
344609008270	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
344609008271	hemolysin; Provisional; Region: PRK15087
344609008272	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
344609008273	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
344609008274	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
344609008275	beta-galactosidase; Region: BGL; TIGR03356
344609008276	putative NAD(P)-binding oxidoreductase; Provisional; Region: PRK09730
344609008277	classical (c) SDRs; Region: SDR_c; cd05233
344609008278	NAD(P) binding site [chemical binding]; other site
344609008279	active site
344609008280	glycine dehydrogenase; Provisional; Region: PRK05367
344609008281	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
344609008282	tetramer interface [polypeptide binding]; other site
344609008283	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609008284	catalytic residue [active]
344609008285	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
344609008286	tetramer interface [polypeptide binding]; other site
344609008287	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609008288	catalytic residue [active]
344609008289	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
344609008290	lipoyl attachment site [posttranslational modification]; other site
344609008291	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
344609008292	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
344609008293	oxidoreductase; Provisional; Region: PRK08013
344609008294	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
344609008295	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
344609008296	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
344609008297	proline aminopeptidase P II; Provisional; Region: PRK10879
344609008298	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
344609008299	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
344609008300	active site
344609008301	hypothetical protein; Reviewed; Region: PRK01736
344609008302	Z-ring-associated protein; Provisional; Region: PRK10972
344609008303	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
344609008304	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
344609008305	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
344609008306	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
344609008307	ligand binding site [chemical binding]; other site
344609008308	NAD binding site [chemical binding]; other site
344609008309	tetramer interface [polypeptide binding]; other site
344609008310	catalytic site [active]
344609008311	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
344609008312	L-serine binding site [chemical binding]; other site
344609008313	ACT domain interface; other site
344609008314	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
344609008315	tetramer (dimer of dimers) interface [polypeptide binding]; other site
344609008316	active site
344609008317	dimer interface [polypeptide binding]; other site
344609008318	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
344609008319	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609008320	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
344609008321	putative dimerization interface [polypeptide binding]; other site
344609008322	membrane ATPase/protein kinase; Provisional; Region: PRK09435
344609008323	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
344609008324	Walker A; other site
344609008325	methylmalonyl-CoA decarboxylase; Provisional; Region: PRK11423
344609008326	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
344609008327	substrate binding site [chemical binding]; other site
344609008328	oxyanion hole (OAH) forming residues; other site
344609008329	trimer interface [polypeptide binding]; other site
344609008330	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008331	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609008332	Transcriptional regulator [Transcription]; Region: LysR; COG0583
344609008333	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
344609008334	dimerization interface [polypeptide binding]; other site
344609008335	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609008336	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609008337	Uncharacterized conserved protein [Function unknown]; Region: COG2968
344609008338	oxidative stress defense protein; Provisional; Region: PRK11087
344609008339	arginine exporter protein; Provisional; Region: PRK09304
344609008340	mechanosensitive channel MscS; Provisional; Region: PRK10334
344609008341	Mechanosensitive ion channel; Region: MS_channel; pfam00924
344609008342	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
344609008343	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
344609008344	active site
344609008345	intersubunit interface [polypeptide binding]; other site
344609008346	zinc binding site [ion binding]; other site
344609008347	Na+ binding site [ion binding]; other site
344609008348	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
344609008349	Phosphoglycerate kinase; Region: PGK; pfam00162
344609008350	substrate binding site [chemical binding]; other site
344609008351	hinge regions; other site
344609008352	ADP binding site [chemical binding]; other site
344609008353	catalytic site [active]
344609008354	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
344609008355	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
344609008356	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
344609008357	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
344609008358	trimer interface [polypeptide binding]; other site
344609008359	putative Zn binding site [ion binding]; other site
344609008360	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
344609008361	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
344609008362	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
344609008363	Walker A/P-loop; other site
344609008364	ATP binding site [chemical binding]; other site
344609008365	Q-loop/lid; other site
344609008366	ABC transporter signature motif; other site
344609008367	Walker B; other site
344609008368	D-loop; other site
344609008369	H-loop/switch region; other site
344609008370	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
344609008371	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
344609008372	Walker A/P-loop; other site
344609008373	ATP binding site [chemical binding]; other site
344609008374	Q-loop/lid; other site
344609008375	ABC transporter signature motif; other site
344609008376	Walker B; other site
344609008377	D-loop; other site
344609008378	H-loop/switch region; other site
344609008379	nucleoside triphosphate hydrolase domain-containing protein; Reviewed; Region: PRK09270
344609008380	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
344609008381	active site
344609008382	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
344609008383	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10022
344609008384	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008385	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
344609008386	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
344609008387	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
344609008388	active site
344609008389	P-loop; other site
344609008390	phosphorylation site [posttranslational modification]
344609008391	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
344609008392	active site
344609008393	phosphorylation site [posttranslational modification]
344609008394	transketolase; Reviewed; Region: PRK12753
344609008395	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
344609008396	TPP-binding site [chemical binding]; other site
344609008397	dimer interface [polypeptide binding]; other site
344609008398	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
344609008399	PYR/PP interface [polypeptide binding]; other site
344609008400	dimer interface [polypeptide binding]; other site
344609008401	TPP binding site [chemical binding]; other site
344609008402	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
344609008403	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
344609008404	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
344609008405	agmatinase; Region: agmatinase; TIGR01230
344609008406	oligomer interface [polypeptide binding]; other site
344609008407	putative active site [active]
344609008408	Mn binding site [ion binding]; other site
344609008409	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
344609008410	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
344609008411	dimer interface [polypeptide binding]; other site
344609008412	active site
344609008413	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
344609008414	catalytic residues [active]
344609008415	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
344609008416	Virulence promoting factor; Region: YqgB; pfam11036
344609008417	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
344609008418	S-adenosylmethionine synthetase; Validated; Region: PRK05250
344609008419	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
344609008420	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
344609008421	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
344609008422	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
344609008423	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609008424	putative substrate translocation pore; other site
344609008425	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609008426	hypothetical protein; Provisional; Region: PRK04860
344609008427	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
344609008428	DNA-specific endonuclease I; Provisional; Region: PRK15137
344609008429	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
344609008430	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
344609008431	RNA methyltransferase, RsmE family; Region: TIGR00046
344609008432	glutathione synthetase; Provisional; Region: PRK05246
344609008433	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
344609008434	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
344609008435	hypothetical protein; Validated; Region: PRK00228
344609008436	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
344609008437	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
344609008438	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
344609008439	Walker A motif; other site
344609008440	ATP binding site [chemical binding]; other site
344609008441	Walker B motif; other site
344609008442	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
344609008443	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
344609008444	catalytic residue [active]
344609008445	YGGT family; Region: YGGT; pfam02325
344609008446	YGGT family; Region: YGGT; pfam02325
344609008447	hypothetical protein; Validated; Region: PRK05090
344609008448	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
344609008449	active site
344609008450	dimerization interface [polypeptide binding]; other site
344609008451	HemN family oxidoreductase; Provisional; Region: PRK05660
344609008452	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
344609008453	FeS/SAM binding site; other site
344609008454	HemN C-terminal domain; Region: HemN_C; pfam06969
344609008455	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
344609008456	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
344609008457	homodimer interface [polypeptide binding]; other site
344609008458	active site
344609008459	hypothetical protein; Provisional; Region: PRK10626
344609008460	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
344609008461	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
344609008462	hypothetical protein; Provisional; Region: PRK11702
344609008463	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
344609008464	adenine DNA glycosylase; Provisional; Region: PRK10880
344609008465	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
344609008466	minor groove reading motif; other site
344609008467	helix-hairpin-helix signature motif; other site
344609008468	substrate binding pocket [chemical binding]; other site
344609008469	active site
344609008470	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
344609008471	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
344609008472	DNA binding and oxoG recognition site [nucleotide binding]
344609008473	oxidative damage protection protein; Provisional; Region: PRK05408
344609008474	murein transglycosylase C; Provisional; Region: mltC; PRK11671
344609008475	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
344609008476	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
344609008477	N-acetyl-D-glucosamine binding site [chemical binding]; other site
344609008478	catalytic residue [active]
344609008479	nucleoside transporter; Region: 2A0110; TIGR00889
344609008480	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
344609008481	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609008482	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609008483	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609008484	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
344609008485	putative general secretion pathway protein YghD; Provisional; Region: PRK09731
344609008486	type II secretion system protein L; Region: typeII_sec_gspL; TIGR01709
344609008487	GspL-like protein; Provisional; Region: PRK09662
344609008488	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
344609008489	type II secretion system protein J; Region: gspJ; TIGR01711
344609008490	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
344609008491	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
344609008492	type II secretion system protein I; Region: gspI; TIGR01707
344609008493	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
344609008494	Prokaryotic N-terminal methylation motif; Region: N_methyl; pfam07963
344609008495	Type II transport protein GspH; Region: GspH; pfam12019
344609008496	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
344609008497	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
344609008498	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
344609008499	type II secretion system protein F; Region: GspF; TIGR02120
344609008500	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
344609008501	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
344609008502	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609008503	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609008504	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609008505	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609008506	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609008507	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609008508	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609008509	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
344609008510	CHAP domain; Region: CHAP; pfam05257
344609008511	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
344609008512	putative S-transferase; Provisional; Region: PRK11752
344609008513	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
344609008514	C-terminal domain interface [polypeptide binding]; other site
344609008515	GSH binding site (G-site) [chemical binding]; other site
344609008516	dimer interface [polypeptide binding]; other site
344609008517	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
344609008518	dimer interface [polypeptide binding]; other site
344609008519	N-terminal domain interface [polypeptide binding]; other site
344609008520	active site
344609008521	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
344609008522	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
344609008523	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
344609008524	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
344609008525	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
344609008526	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
344609008527	putative substrate-binding site; other site
344609008528	nickel binding site [ion binding]; other site
344609008529	hydrogenase 2 large subunit; Provisional; Region: PRK10467
344609008530	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
344609008531	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
344609008532	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
344609008533	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
344609008534	4Fe-4S binding domain; Region: Fer4_6; pfam12837
344609008535	hydrogenase 2 small subunit; Provisional; Region: PRK10468
344609008536	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
344609008537	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
344609008538	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
344609008539	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008540	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
344609008541	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
344609008542	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
344609008543	active site
344609008544	catalytic tetrad [active]
344609008545	hypothetical protein; Provisional; Region: PRK05208
344609008546	oxidoreductase; Provisional; Region: PRK07985
344609008547	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
344609008548	NAD binding site [chemical binding]; other site
344609008549	metal binding site [ion binding]; metal-binding site
344609008550	active site
344609008551	biopolymer transport protein ExbD; Provisional; Region: PRK11267
344609008552	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
344609008553	biopolymer transport protein ExbB; Provisional; Region: PRK10414
344609008554	cystathionine beta-lyase; Provisional; Region: PRK08114
344609008555	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
344609008556	homodimer interface [polypeptide binding]; other site
344609008557	substrate-cofactor binding pocket; other site
344609008558	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609008559	catalytic residue [active]
344609008560	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
344609008561	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
344609008562	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
344609008563	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
344609008564	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609008565	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609008566	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
344609008567	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
344609008568	dimer interface [polypeptide binding]; other site
344609008569	active site
344609008570	metal binding site [ion binding]; metal-binding site
344609008571	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
344609008572	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
344609008573	active site
344609008574	catalytic tetrad [active]
344609008575	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
344609008576	putative outer membrane lipoprotein; Provisional; Region: PRK09973
344609008577	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008578	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609008579	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609008580	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609008581	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609008582	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609008583	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609008584	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609008585	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
344609008586	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
344609008587	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
344609008588	hypothetical protein; Provisional; Region: PRK01254
344609008589	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
344609008590	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
344609008591	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008592	FtsI repressor; Provisional; Region: PRK10883
344609008593	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
344609008594	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
344609008595	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
344609008596	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
344609008597	putative acyl-acceptor binding pocket; other site
344609008598	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
344609008599	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
344609008600	CAP-like domain; other site
344609008601	active site
344609008602	primary dimer interface [polypeptide binding]; other site
344609008603	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
344609008604	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
344609008605	TIGR00156 family protein; Region: TIGR00156
344609008606	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
344609008607	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609008608	active site
344609008609	phosphorylation site [posttranslational modification]
344609008610	intermolecular recognition site; other site
344609008611	dimerization interface [polypeptide binding]; other site
344609008612	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
344609008613	DNA binding site [nucleotide binding]
344609008614	sensor protein QseC; Provisional; Region: PRK10337
344609008615	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609008616	dimer interface [polypeptide binding]; other site
344609008617	phosphorylation site [posttranslational modification]
344609008618	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609008619	ATP binding site [chemical binding]; other site
344609008620	Mg2+ binding site [ion binding]; other site
344609008621	G-X-G motif; other site
344609008622	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
344609008623	Uncharacterized conserved protein [Function unknown]; Region: COG1359
344609008624	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
344609008625	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609008626	ATP binding site [chemical binding]; other site
344609008627	Mg2+ binding site [ion binding]; other site
344609008628	G-X-G motif; other site
344609008629	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
344609008630	anchoring element; other site
344609008631	dimer interface [polypeptide binding]; other site
344609008632	ATP binding site [chemical binding]; other site
344609008633	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
344609008634	active site
344609008635	metal binding site [ion binding]; metal-binding site
344609008636	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
344609008637	esterase YqiA; Provisional; Region: PRK11071
344609008638	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
344609008639	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
344609008640	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
344609008641	active site
344609008642	metal binding site [ion binding]; metal-binding site
344609008643	hexamer interface [polypeptide binding]; other site
344609008644	putative dehydrogenase; Provisional; Region: PRK11039
344609008645	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
344609008646	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
344609008647	dimer interface [polypeptide binding]; other site
344609008648	ADP-ribose binding site [chemical binding]; other site
344609008649	active site
344609008650	nudix motif; other site
344609008651	metal binding site [ion binding]; metal-binding site
344609008652	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
344609008653	hypothetical protein; Provisional; Region: PRK11653
344609008654	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
344609008655	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
344609008656	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
344609008657	putative active site [active]
344609008658	metal binding site [ion binding]; metal-binding site
344609008659	zinc transporter ZupT; Provisional; Region: PRK04201
344609008660	ZIP Zinc transporter; Region: Zip; pfam02535
344609008661	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008662	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
344609008663	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
344609008664	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
344609008665	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008666	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
344609008667	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008668	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
344609008669	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
344609008670	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
344609008671	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
344609008672	putative ribose interaction site [chemical binding]; other site
344609008673	putative ADP binding site [chemical binding]; other site
344609008674	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
344609008675	active site
344609008676	nucleotide binding site [chemical binding]; other site
344609008677	HIGH motif; other site
344609008678	KMSKS motif; other site
344609008679	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
344609008680	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
344609008681	metal binding triad; other site
344609008682	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
344609008683	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
344609008684	metal binding triad; other site
344609008685	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
344609008686	Uncharacterized conserved protein [Function unknown]; Region: COG3025
344609008687	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
344609008688	putative active site [active]
344609008689	putative metal binding residues [ion binding]; other site
344609008690	signature motif; other site
344609008691	putative triphosphate binding site [ion binding]; other site
344609008692	CHAD domain; Region: CHAD; pfam05235
344609008693	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
344609008694	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
344609008695	active site
344609008696	NTP binding site [chemical binding]; other site
344609008697	metal binding triad [ion binding]; metal-binding site
344609008698	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
344609008699	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
344609008700	Zn2+ binding site [ion binding]; other site
344609008701	Mg2+ binding site [ion binding]; other site
344609008702	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
344609008703	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
344609008704	homooctamer interface [polypeptide binding]; other site
344609008705	active site
344609008706	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
344609008707	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
344609008708	UGMP family protein; Validated; Region: PRK09604
344609008709	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
344609008710	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
344609008711	DNA primase; Validated; Region: dnaG; PRK05667
344609008712	CHC2 zinc finger; Region: zf-CHC2; pfam01807
344609008713	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
344609008714	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
344609008715	active site
344609008716	metal binding site [ion binding]; metal-binding site
344609008717	interdomain interaction site; other site
344609008718	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
344609008719	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
344609008720	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
344609008721	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
344609008722	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
344609008723	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
344609008724	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
344609008725	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
344609008726	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
344609008727	DNA binding residues [nucleotide binding]
344609008728	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609008729	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609008730	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609008731	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
344609008732	active site
344609008733	SUMO-1 interface [polypeptide binding]; other site
344609008734	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
344609008735	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
344609008736	FAD binding pocket [chemical binding]; other site
344609008737	FAD binding motif [chemical binding]; other site
344609008738	phosphate binding motif [ion binding]; other site
344609008739	NAD binding pocket [chemical binding]; other site
344609008740	Predicted transcriptional regulators [Transcription]; Region: COG1695
344609008741	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
344609008742	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
344609008743	PAS fold; Region: PAS_3; pfam08447
344609008744	putative active site [active]
344609008745	heme pocket [chemical binding]; other site
344609008746	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
344609008747	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
344609008748	dimer interface [polypeptide binding]; other site
344609008749	putative CheW interface [polypeptide binding]; other site
344609008750	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609008751	Domain of unknown function (DUF386); Region: DUF386; cl01047
344609008752	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
344609008753	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
344609008754	active site
344609008755	FMN binding site [chemical binding]; other site
344609008756	2,4-decadienoyl-CoA binding site; other site
344609008757	catalytic residue [active]
344609008758	4Fe-4S cluster binding site [ion binding]; other site
344609008759	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
344609008760	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
344609008761	non-specific DNA binding site [nucleotide binding]; other site
344609008762	salt bridge; other site
344609008763	sequence-specific DNA binding site [nucleotide binding]; other site
344609008764	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
344609008765	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609008766	S-adenosylmethionine binding site [chemical binding]; other site
344609008767	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
344609008768	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
344609008769	putative active site [active]
344609008770	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
344609008771	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
344609008772	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
344609008773	yybP-ykoY leader
344609008774	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
344609008775	serine/threonine transporter SstT; Provisional; Region: PRK13628
344609008776	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
344609008777	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
344609008778	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
344609008779	galactarate dehydratase; Region: galactar-dH20; TIGR03248
344609008780	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
344609008781	Glucuronate isomerase; Region: UxaC; pfam02614
344609008782	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
344609008783	D-galactonate transporter; Region: 2A0114; TIGR00893
344609008784	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609008785	putative substrate translocation pore; other site
344609008786	CblD like pilus biogenesis initiator; Region: CblD; cl06460
344609008787	efflux system membrane protein; Provisional; Region: PRK11594
344609008788	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
344609008789	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
344609008790	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
344609008791	RNAase interaction site [polypeptide binding]; other site
344609008792	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
344609008793	arginine repressor; Provisional; Region: PRK05066
344609008794	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
344609008795	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
344609008796	malate dehydrogenase; Provisional; Region: PRK05086
344609008797	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
344609008798	NAD binding site [chemical binding]; other site
344609008799	dimerization interface [polypeptide binding]; other site
344609008800	Substrate binding site [chemical binding]; other site
344609008801	serine endoprotease; Provisional; Region: PRK10898
344609008802	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
344609008803	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
344609008804	serine endoprotease; Provisional; Region: PRK10139
344609008805	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
344609008806	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
344609008807	protein binding site [polypeptide binding]; other site
344609008808	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
344609008809	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
344609008810	hypothetical protein; Provisional; Region: PRK11677
344609008811	Predicted ATPase [General function prediction only]; Region: COG1485
344609008812	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
344609008813	23S rRNA interface [nucleotide binding]; other site
344609008814	L3 interface [polypeptide binding]; other site
344609008815	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
344609008816	stringent starvation protein A; Provisional; Region: sspA; PRK09481
344609008817	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
344609008818	C-terminal domain interface [polypeptide binding]; other site
344609008819	putative GSH binding site (G-site) [chemical binding]; other site
344609008820	dimer interface [polypeptide binding]; other site
344609008821	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
344609008822	dimer interface [polypeptide binding]; other site
344609008823	N-terminal domain interface [polypeptide binding]; other site
344609008824	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
344609008825	transcriptional regulator NanR; Provisional; Region: PRK03837
344609008826	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
344609008827	DNA-binding site [nucleotide binding]; DNA binding site
344609008828	FCD domain; Region: FCD; pfam07729
344609008829	N-acetylneuraminate lyase; Region: nanA; TIGR00683
344609008830	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
344609008831	inhibitor site; inhibition site
344609008832	active site
344609008833	dimer interface [polypeptide binding]; other site
344609008834	catalytic residue [active]
344609008835	putative sialic acid transporter; Provisional; Region: PRK03893
344609008836	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609008837	putative substrate translocation pore; other site
344609008838	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
344609008839	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
344609008840	putative active site cavity [active]
344609008841	N-acetylmannosamine kinase; Provisional; Region: PRK05082
344609008842	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
344609008843	nucleotide binding site [chemical binding]; other site
344609008844	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
344609008845	Domain of unknown function (DUF386); Region: DUF386; cl01047
344609008846	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
344609008847	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
344609008848	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
344609008849	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
344609008850	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
344609008851	active site
344609008852	dimer interface [polypeptide binding]; other site
344609008853	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
344609008854	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
344609008855	active site
344609008856	FMN binding site [chemical binding]; other site
344609008857	substrate binding site [chemical binding]; other site
344609008858	3Fe-4S cluster binding site [ion binding]; other site
344609008859	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
344609008860	domain interface; other site
344609008861	radical SAM protein, TIGR01212 family; Region: TIGR01212
344609008862	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
344609008863	FeS/SAM binding site; other site
344609008864	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
344609008865	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
344609008866	putative active site [active]
344609008867	heme pocket [chemical binding]; other site
344609008868	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609008869	dimer interface [polypeptide binding]; other site
344609008870	phosphorylation site [posttranslational modification]
344609008871	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609008872	ATP binding site [chemical binding]; other site
344609008873	Mg2+ binding site [ion binding]; other site
344609008874	G-X-G motif; other site
344609008875	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609008876	active site
344609008877	phosphorylation site [posttranslational modification]
344609008878	intermolecular recognition site; other site
344609008879	dimerization interface [polypeptide binding]; other site
344609008880	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
344609008881	putative binding surface; other site
344609008882	active site
344609008883	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
344609008884	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
344609008885	conserved cys residue [active]
344609008886	hypothetical protein; Provisional; Region: PRK10345
344609008887	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
344609008888	dimerization domain swap beta strand [polypeptide binding]; other site
344609008889	regulatory protein interface [polypeptide binding]; other site
344609008890	active site
344609008891	regulatory phosphorylation site [posttranslational modification]; other site
344609008892	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
344609008893	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
344609008894	active site
344609008895	phosphorylation site [posttranslational modification]
344609008896	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
344609008897	30S subunit binding site; other site
344609008898	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
344609008899	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
344609008900	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
344609008901	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
344609008902	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
344609008903	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
344609008904	Walker A/P-loop; other site
344609008905	ATP binding site [chemical binding]; other site
344609008906	Q-loop/lid; other site
344609008907	ABC transporter signature motif; other site
344609008908	Walker B; other site
344609008909	D-loop; other site
344609008910	H-loop/switch region; other site
344609008911	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
344609008912	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
344609008913	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
344609008914	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
344609008915	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
344609008916	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
344609008917	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
344609008918	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
344609008919	putative active site [active]
344609008920	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
344609008921	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
344609008922	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
344609008923	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
344609008924	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
344609008925	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
344609008926	Walker A/P-loop; other site
344609008927	ATP binding site [chemical binding]; other site
344609008928	Q-loop/lid; other site
344609008929	ABC transporter signature motif; other site
344609008930	Walker B; other site
344609008931	D-loop; other site
344609008932	H-loop/switch region; other site
344609008933	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
344609008934	conserved hypothetical integral membrane protein; Region: TIGR00056
344609008935	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
344609008936	mce related protein; Region: MCE; pfam02470
344609008937	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
344609008938	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
344609008939	anti sigma factor interaction site; other site
344609008940	regulatory phosphorylation site [posttranslational modification]; other site
344609008941	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
344609008942	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
344609008943	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
344609008944	hinge; other site
344609008945	active site
344609008946	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
344609008947	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
344609008948	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
344609008949	substrate binding pocket [chemical binding]; other site
344609008950	chain length determination region; other site
344609008951	substrate-Mg2+ binding site; other site
344609008952	catalytic residues [active]
344609008953	aspartate-rich region 1; other site
344609008954	active site lid residues [active]
344609008955	aspartate-rich region 2; other site
344609008956	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
344609008957	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
344609008958	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
344609008959	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
344609008960	EamA-like transporter family; Region: EamA; pfam00892
344609008961	EamA-like transporter family; Region: EamA; pfam00892
344609008962	GTPase CgtA; Reviewed; Region: obgE; PRK12298
344609008963	GTP1/OBG; Region: GTP1_OBG; pfam01018
344609008964	Obg GTPase; Region: Obg; cd01898
344609008965	G1 box; other site
344609008966	GTP/Mg2+ binding site [chemical binding]; other site
344609008967	Switch I region; other site
344609008968	G2 box; other site
344609008969	G3 box; other site
344609008970	Switch II region; other site
344609008971	G4 box; other site
344609008972	G5 box; other site
344609008973	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
344609008974	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
344609008975	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
344609008976	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
344609008977	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
344609008978	RNA-binding protein YhbY; Provisional; Region: PRK10343
344609008979	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
344609008980	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609008981	S-adenosylmethionine binding site [chemical binding]; other site
344609008982	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
344609008983	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609008984	Walker A motif; other site
344609008985	ATP binding site [chemical binding]; other site
344609008986	Walker B motif; other site
344609008987	arginine finger; other site
344609008988	Peptidase family M41; Region: Peptidase_M41; pfam01434
344609008989	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
344609008990	dihydropteroate synthase; Region: DHPS; TIGR01496
344609008991	substrate binding pocket [chemical binding]; other site
344609008992	dimer interface [polypeptide binding]; other site
344609008993	inhibitor binding site; inhibition site
344609008994	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
344609008995	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
344609008996	active site
344609008997	substrate binding site [chemical binding]; other site
344609008998	metal binding site [ion binding]; metal-binding site
344609008999	Preprotein translocase SecG subunit; Region: SecG; pfam03840
344609009000	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609009001	argininosuccinate synthase; Validated; Region: PRK05370
344609009002	ribosome maturation protein RimP; Reviewed; Region: PRK00092
344609009003	Sm and related proteins; Region: Sm_like; cl00259
344609009004	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
344609009005	putative oligomer interface [polypeptide binding]; other site
344609009006	putative RNA binding site [nucleotide binding]; other site
344609009007	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
344609009008	NusA N-terminal domain; Region: NusA_N; pfam08529
344609009009	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
344609009010	RNA binding site [nucleotide binding]; other site
344609009011	homodimer interface [polypeptide binding]; other site
344609009012	NusA-like KH domain; Region: KH_5; pfam13184
344609009013	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
344609009014	G-X-X-G motif; other site
344609009015	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
344609009016	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
344609009017	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
344609009018	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
344609009019	translation initiation factor IF-2; Region: IF-2; TIGR00487
344609009020	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
344609009021	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
344609009022	G1 box; other site
344609009023	putative GEF interaction site [polypeptide binding]; other site
344609009024	GTP/Mg2+ binding site [chemical binding]; other site
344609009025	Switch I region; other site
344609009026	G2 box; other site
344609009027	G3 box; other site
344609009028	Switch II region; other site
344609009029	G4 box; other site
344609009030	G5 box; other site
344609009031	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
344609009032	Translation-initiation factor 2; Region: IF-2; pfam11987
344609009033	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
344609009034	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
344609009035	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
344609009036	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
344609009037	RNA binding site [nucleotide binding]; other site
344609009038	active site
344609009039	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
344609009040	Ribosomal S15 leader
344609009041	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
344609009042	16S/18S rRNA binding site [nucleotide binding]; other site
344609009043	S13e-L30e interaction site [polypeptide binding]; other site
344609009044	25S rRNA binding site [nucleotide binding]; other site
344609009045	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
344609009046	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
344609009047	RNase E interface [polypeptide binding]; other site
344609009048	trimer interface [polypeptide binding]; other site
344609009049	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
344609009050	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
344609009051	RNase E interface [polypeptide binding]; other site
344609009052	trimer interface [polypeptide binding]; other site
344609009053	active site
344609009054	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
344609009055	putative nucleic acid binding region [nucleotide binding]; other site
344609009056	G-X-X-G motif; other site
344609009057	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
344609009058	RNA binding site [nucleotide binding]; other site
344609009059	domain interface; other site
344609009060	lipoprotein NlpI; Provisional; Region: PRK11189
344609009061	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
344609009062	binding surface
344609009063	TPR motif; other site
344609009064	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
344609009065	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
344609009066	ATP binding site [chemical binding]; other site
344609009067	Mg++ binding site [ion binding]; other site
344609009068	motif III; other site
344609009069	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
344609009070	nucleotide binding region [chemical binding]; other site
344609009071	ATP-binding site [chemical binding]; other site
344609009072	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
344609009073	putative RNA binding site [nucleotide binding]; other site
344609009074	tryptophan permease; Provisional; Region: PRK10483
344609009075	aromatic amino acid transport protein; Region: araaP; TIGR00837
344609009076	hypothetical protein; Provisional; Region: PRK10508
344609009077	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
344609009078	putative protease; Provisional; Region: PRK15447
344609009079	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
344609009080	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
344609009081	Peptidase family U32; Region: Peptidase_U32; pfam01136
344609009082	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
344609009083	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
344609009084	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
344609009085	Coenzyme A binding pocket [chemical binding]; other site
344609009086	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
344609009087	GIY-YIG motif/motif A; other site
344609009088	putative active site [active]
344609009089	putative metal binding site [ion binding]; other site
344609009090	hypothetical protein; Provisional; Region: PRK03467
344609009091	intracellular protease, PfpI family; Region: PfpI; TIGR01382
344609009092	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
344609009093	proposed catalytic triad [active]
344609009094	conserved cys residue [active]
344609009095	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
344609009096	NADH(P)-binding; Region: NAD_binding_10; pfam13460
344609009097	NAD binding site [chemical binding]; other site
344609009098	active site
344609009099	Predicted permease; Region: DUF318; pfam03773
344609009100	outer membrane lipoprotein; Provisional; Region: PRK11023
344609009101	BON domain; Region: BON; pfam04972
344609009102	BON domain; Region: BON; pfam04972
344609009103	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
344609009104	dimer interface [polypeptide binding]; other site
344609009105	active site
344609009106	TIGR00252 family protein; Region: TIGR00252
344609009107	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
344609009108	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
344609009109	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
344609009110	putative ligand binding site [chemical binding]; other site
344609009111	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
344609009112	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
344609009113	putative SAM binding site [chemical binding]; other site
344609009114	putative homodimer interface [polypeptide binding]; other site
344609009115	HTH-like domain; Region: HTH_21; pfam13276
344609009116	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609009117	Integrase core domain; Region: rve; pfam00665
344609009118	Integrase core domain; Region: rve_3; pfam13683
344609009119	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609009120	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
344609009121	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
344609009122	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
344609009123	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
344609009124	intersubunit interface [polypeptide binding]; other site
344609009125	active site
344609009126	zinc binding site [ion binding]; other site
344609009127	Na+ binding site [ion binding]; other site
344609009128	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
344609009129	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
344609009130	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
344609009131	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
344609009132	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
344609009133	substrate binding site [chemical binding]; other site
344609009134	ATP binding site [chemical binding]; other site
344609009135	hypothetical protein; Provisional; Region: PRK10633
344609009136	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
344609009137	Na binding site [ion binding]; other site
344609009138	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
344609009139	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
344609009140	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
344609009141	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
344609009142	FMN binding site [chemical binding]; other site
344609009143	active site
344609009144	catalytic residues [active]
344609009145	substrate binding site [chemical binding]; other site
344609009146	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
344609009147	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
344609009148	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
344609009149	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609009150	DNA methylase; Region: N6_N4_Mtase; pfam01555
344609009151	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
344609009152	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
344609009153	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
344609009154	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
344609009155	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
344609009156	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
344609009157	HlyD family secretion protein; Region: HlyD_3; pfam13437
344609009158	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
344609009159	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
344609009160	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
344609009161	substrate binding pocket [chemical binding]; other site
344609009162	membrane-bound complex binding site; other site
344609009163	hinge residues; other site
344609009164	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
344609009165	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609009166	dimer interface [polypeptide binding]; other site
344609009167	conserved gate region; other site
344609009168	putative PBP binding loops; other site
344609009169	ABC-ATPase subunit interface; other site
344609009170	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
344609009171	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
344609009172	Walker A/P-loop; other site
344609009173	ATP binding site [chemical binding]; other site
344609009174	Q-loop/lid; other site
344609009175	ABC transporter signature motif; other site
344609009176	Walker B; other site
344609009177	D-loop; other site
344609009178	H-loop/switch region; other site
344609009179	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
344609009180	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
344609009181	trimer interface [polypeptide binding]; other site
344609009182	putative metal binding site [ion binding]; other site
344609009183	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
344609009184	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
344609009185	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
344609009186	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
344609009187	shikimate binding site; other site
344609009188	NAD(P) binding site [chemical binding]; other site
344609009189	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
344609009190	hypothetical protein; Validated; Region: PRK03430
344609009191	hypothetical protein; Provisional; Region: PRK10736
344609009192	DNA protecting protein DprA; Region: dprA; TIGR00732
344609009193	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
344609009194	active site
344609009195	catalytic residues [active]
344609009196	metal binding site [ion binding]; metal-binding site
344609009197	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
344609009198	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
344609009199	putative active site [active]
344609009200	substrate binding site [chemical binding]; other site
344609009201	putative cosubstrate binding site; other site
344609009202	catalytic site [active]
344609009203	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
344609009204	substrate binding site [chemical binding]; other site
344609009205	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
344609009206	putative RNA binding site [nucleotide binding]; other site
344609009207	16S rRNA methyltransferase B; Provisional; Region: PRK10901
344609009208	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609009209	S-adenosylmethionine binding site [chemical binding]; other site
344609009210	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
344609009211	TrkA-N domain; Region: TrkA_N; pfam02254
344609009212	TrkA-C domain; Region: TrkA_C; pfam02080
344609009213	TrkA-N domain; Region: TrkA_N; pfam02254
344609009214	TrkA-C domain; Region: TrkA_C; pfam02080
344609009215	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609009216	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609009217	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609009218	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609009219	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609009220	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609009221	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609009222	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
344609009223	Large-conductance mechanosensitive channel, MscL; Region: MscL; pfam01741
344609009224	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
344609009225	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
344609009226	DNA binding residues [nucleotide binding]
344609009227	dimer interface [polypeptide binding]; other site
344609009228	metal binding site [ion binding]; metal-binding site
344609009229	hypothetical protein; Provisional; Region: PRK10203
344609009230	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
344609009231	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
344609009232	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
344609009233	alphaNTD homodimer interface [polypeptide binding]; other site
344609009234	alphaNTD - beta interaction site [polypeptide binding]; other site
344609009235	alphaNTD - beta' interaction site [polypeptide binding]; other site
344609009236	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
344609009237	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
344609009238	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
344609009239	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
344609009240	RNA binding surface [nucleotide binding]; other site
344609009241	30S ribosomal protein S11; Validated; Region: PRK05309
344609009242	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
344609009243	30S ribosomal protein S13; Region: bact_S13; TIGR03631
344609009244	Alpha operon ribosome binding site
344609009245	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
344609009246	SecY translocase; Region: SecY; pfam00344
344609009247	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
344609009248	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
344609009249	23S rRNA binding site [nucleotide binding]; other site
344609009250	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
344609009251	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
344609009252	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
344609009253	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
344609009254	23S rRNA interface [nucleotide binding]; other site
344609009255	5S rRNA interface [nucleotide binding]; other site
344609009256	L27 interface [polypeptide binding]; other site
344609009257	L5 interface [polypeptide binding]; other site
344609009258	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
344609009259	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
344609009260	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
344609009261	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
344609009262	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
344609009263	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
344609009264	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
344609009265	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
344609009266	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
344609009267	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
344609009268	RNA binding site [nucleotide binding]; other site
344609009269	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
344609009270	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
344609009271	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
344609009272	23S rRNA interface [nucleotide binding]; other site
344609009273	putative translocon interaction site; other site
344609009274	signal recognition particle (SRP54) interaction site; other site
344609009275	L23 interface [polypeptide binding]; other site
344609009276	trigger factor interaction site; other site
344609009277	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
344609009278	23S rRNA interface [nucleotide binding]; other site
344609009279	5S rRNA interface [nucleotide binding]; other site
344609009280	putative antibiotic binding site [chemical binding]; other site
344609009281	L25 interface [polypeptide binding]; other site
344609009282	L27 interface [polypeptide binding]; other site
344609009283	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
344609009284	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
344609009285	G-X-X-G motif; other site
344609009286	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
344609009287	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
344609009288	protein-rRNA interface [nucleotide binding]; other site
344609009289	putative translocon binding site; other site
344609009290	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
344609009291	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
344609009292	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
344609009293	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
344609009294	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
344609009295	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
344609009296	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
344609009297	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
344609009298	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609009299	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609009300	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609009301	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609009302	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609009303	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609009304	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609009305	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609009306	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609009307	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609009308	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
344609009309	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
344609009310	heme binding site [chemical binding]; other site
344609009311	ferroxidase pore; other site
344609009312	ferroxidase diiron center [ion binding]; other site
344609009313	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
344609009314	elongation factor Tu; Reviewed; Region: PRK00049
344609009315	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
344609009316	G1 box; other site
344609009317	GEF interaction site [polypeptide binding]; other site
344609009318	GTP/Mg2+ binding site [chemical binding]; other site
344609009319	Switch I region; other site
344609009320	G2 box; other site
344609009321	G3 box; other site
344609009322	Switch II region; other site
344609009323	G4 box; other site
344609009324	G5 box; other site
344609009325	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
344609009326	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
344609009327	Antibiotic Binding Site [chemical binding]; other site
344609009328	elongation factor G; Reviewed; Region: PRK00007
344609009329	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
344609009330	G1 box; other site
344609009331	putative GEF interaction site [polypeptide binding]; other site
344609009332	GTP/Mg2+ binding site [chemical binding]; other site
344609009333	Switch I region; other site
344609009334	G2 box; other site
344609009335	G3 box; other site
344609009336	Switch II region; other site
344609009337	G4 box; other site
344609009338	G5 box; other site
344609009339	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
344609009340	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
344609009341	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
344609009342	30S ribosomal protein S7; Validated; Region: PRK05302
344609009343	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
344609009344	S17 interaction site [polypeptide binding]; other site
344609009345	S8 interaction site; other site
344609009346	16S rRNA interaction site [nucleotide binding]; other site
344609009347	streptomycin interaction site [chemical binding]; other site
344609009348	23S rRNA interaction site [nucleotide binding]; other site
344609009349	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
344609009350	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
344609009351	sulfur relay protein TusC; Validated; Region: PRK00211
344609009352	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
344609009353	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
344609009354	YheO-like PAS domain; Region: PAS_6; pfam08348
344609009355	HTH domain; Region: HTH_22; pfam13309
344609009356	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
344609009357	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
344609009358	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
344609009359	phi X174 lysis protein; Provisional; Region: PRK02793
344609009360	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
344609009361	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
344609009362	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
344609009363	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
344609009364	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
344609009365	TrkA-N domain; Region: TrkA_N; pfam02254
344609009366	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
344609009367	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
344609009368	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609009369	Walker A/P-loop; other site
344609009370	ATP binding site [chemical binding]; other site
344609009371	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
344609009372	ABC transporter signature motif; other site
344609009373	Walker B; other site
344609009374	D-loop; other site
344609009375	ABC transporter; Region: ABC_tran_2; pfam12848
344609009376	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
344609009377	putative hydrolase; Provisional; Region: PRK10985
344609009378	hypothetical protein; Provisional; Region: PRK04966
344609009379	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
344609009380	active site
344609009381	hypothetical protein; Provisional; Region: PRK10738
344609009382	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609009383	HTH-like domain; Region: HTH_21; pfam13276
344609009384	Integrase core domain; Region: rve; pfam00665
344609009385	Integrase core domain; Region: rve_3; pfam13683
344609009386	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
344609009387	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
344609009388	ligand binding site [chemical binding]; other site
344609009389	flexible hinge region; other site
344609009390	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
344609009391	putative switch regulator; other site
344609009392	non-specific DNA interactions [nucleotide binding]; other site
344609009393	DNA binding site [nucleotide binding]
344609009394	sequence specific DNA binding site [nucleotide binding]; other site
344609009395	putative cAMP binding site [chemical binding]; other site
344609009396	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
344609009397	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
344609009398	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
344609009399	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
344609009400	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
344609009401	inhibitor-cofactor binding pocket; inhibition site
344609009402	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609009403	catalytic residue [active]
344609009404	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
344609009405	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
344609009406	glutamine binding [chemical binding]; other site
344609009407	catalytic triad [active]
344609009408	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
344609009409	cell filamentation protein Fic; Provisional; Region: PRK10347
344609009410	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
344609009411	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
344609009412	substrate binding site [chemical binding]; other site
344609009413	putative transporter; Provisional; Region: PRK03699
344609009414	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609009415	putative substrate translocation pore; other site
344609009416	nitrite reductase subunit NirD; Provisional; Region: PRK14989
344609009417	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
344609009418	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
344609009419	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
344609009420	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
344609009421	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
344609009422	nitrite transporter NirC; Provisional; Region: PRK11562
344609009423	siroheme synthase; Provisional; Region: cysG; PRK10637
344609009424	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
344609009425	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
344609009426	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
344609009427	active site
344609009428	SAM binding site [chemical binding]; other site
344609009429	homodimer interface [polypeptide binding]; other site
344609009430	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609009431	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
344609009432	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
344609009433	hypothetical protein; Provisional; Region: PHA02764
344609009434	fructoselysine 3-epimerase; Provisional; Region: PRK09856
344609009435	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
344609009436	AP (apurinic/apyrimidinic) site pocket; other site
344609009437	DNA interaction; other site
344609009438	Metal-binding active site; metal-binding site
344609009439	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
344609009440	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
344609009441	substrate binding site [chemical binding]; other site
344609009442	ATP binding site [chemical binding]; other site
344609009443	DNA-binding transcriptional regulator FrlR; Provisional; Region: PRK11402
344609009444	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
344609009445	DNA-binding site [nucleotide binding]; DNA binding site
344609009446	UTRA domain; Region: UTRA; pfam07702
344609009447	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
344609009448	DNA topoisomerase III, bacteria and conjugative plasmid; Region: topB; TIGR01056
344609009449	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609009450	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609009451	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609009452	Protein of unknown function DUF2620; Region: DUF2620; pfam10941
344609009453	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
344609009454	active site
344609009455	substrate binding pocket [chemical binding]; other site
344609009456	homodimer interaction site [polypeptide binding]; other site
344609009457	putative mutase; Provisional; Region: PRK12383
344609009458	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; COG1015
344609009459	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme yhfX; Region: PLPDE_III_yhfX_like; cd06811
344609009460	dimer interface [polypeptide binding]; other site
344609009461	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
344609009462	active site
344609009463	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
344609009464	substrate binding site [chemical binding]; other site
344609009465	catalytic residue [active]
344609009466	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
344609009467	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
344609009468	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
344609009469	active site
344609009470	HIGH motif; other site
344609009471	dimer interface [polypeptide binding]; other site
344609009472	KMSKS motif; other site
344609009473	phosphoglycolate phosphatase; Provisional; Region: PRK13222
344609009474	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609009475	motif II; other site
344609009476	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
344609009477	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
344609009478	substrate binding site [chemical binding]; other site
344609009479	hexamer interface [polypeptide binding]; other site
344609009480	metal binding site [ion binding]; metal-binding site
344609009481	DNA adenine methylase; Provisional; Region: PRK10904
344609009482	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
344609009483	cell division protein DamX; Validated; Region: PRK10905
344609009484	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
344609009485	active site
344609009486	dimer interface [polypeptide binding]; other site
344609009487	metal binding site [ion binding]; metal-binding site
344609009488	shikimate kinase; Reviewed; Region: aroK; PRK00131
344609009489	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
344609009490	ADP binding site [chemical binding]; other site
344609009491	magnesium binding site [ion binding]; other site
344609009492	putative shikimate binding site; other site
344609009493	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
344609009494	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
344609009495	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
344609009496	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
344609009497	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
344609009498	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
344609009499	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
344609009500	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
344609009501	Transglycosylase; Region: Transgly; pfam00912
344609009502	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
344609009503	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
344609009504	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
344609009505	ADP-ribose binding site [chemical binding]; other site
344609009506	dimer interface [polypeptide binding]; other site
344609009507	active site
344609009508	nudix motif; other site
344609009509	metal binding site [ion binding]; metal-binding site
344609009510	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
344609009511	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
344609009512	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609009513	motif II; other site
344609009514	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
344609009515	RNA binding surface [nucleotide binding]; other site
344609009516	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
344609009517	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
344609009518	dimerization interface [polypeptide binding]; other site
344609009519	domain crossover interface; other site
344609009520	redox-dependent activation switch; other site
344609009521	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
344609009522	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
344609009523	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
344609009524	active site
344609009525	substrate-binding site [chemical binding]; other site
344609009526	metal-binding site [ion binding]
344609009527	ATP binding site [chemical binding]; other site
344609009528	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
344609009529	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
344609009530	dimerization interface [polypeptide binding]; other site
344609009531	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609009532	dimer interface [polypeptide binding]; other site
344609009533	phosphorylation site [posttranslational modification]
344609009534	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609009535	ATP binding site [chemical binding]; other site
344609009536	G-X-G motif; other site
344609009537	osmolarity response regulator; Provisional; Region: ompR; PRK09468
344609009538	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609009539	active site
344609009540	phosphorylation site [posttranslational modification]
344609009541	intermolecular recognition site; other site
344609009542	dimerization interface [polypeptide binding]; other site
344609009543	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
344609009544	DNA binding site [nucleotide binding]
344609009545	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
344609009546	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
344609009547	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
344609009548	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
344609009549	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
344609009550	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
344609009551	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
344609009552	RNA binding site [nucleotide binding]; other site
344609009553	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609009554	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
344609009555	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
344609009556	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
344609009557	G1 box; other site
344609009558	GTP/Mg2+ binding site [chemical binding]; other site
344609009559	Switch I region; other site
344609009560	G2 box; other site
344609009561	G3 box; other site
344609009562	Switch II region; other site
344609009563	G4 box; other site
344609009564	G5 box; other site
344609009565	Nucleoside recognition; Region: Gate; pfam07670
344609009566	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
344609009567	Nucleoside recognition; Region: Gate; pfam07670
344609009568	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
344609009569	putative transposase; Provisional; Region: PRK09857
344609009570	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
344609009571	carboxylesterase BioH; Provisional; Region: PRK10349
344609009572	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
344609009573	DNA utilization protein GntX; Provisional; Region: PRK11595
344609009574	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
344609009575	active site
344609009576	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
344609009577	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
344609009578	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
344609009579	high-affinity gluconate transporter; Provisional; Region: PRK14984
344609009580	gluconate transporter; Region: gntP; TIGR00791
344609009581	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
344609009582	4-alpha-glucanotransferase; Region: malQ; TIGR00217
344609009583	maltodextrin phosphorylase; Provisional; Region: PRK14985
344609009584	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
344609009585	homodimer interface [polypeptide binding]; other site
344609009586	active site pocket [active]
344609009587	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
344609009588	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
344609009589	putative active site [active]
344609009590	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
344609009591	hypothetical protein; Reviewed; Region: PRK09588
344609009592	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
344609009593	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
344609009594	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609009595	Walker A motif; other site
344609009596	ATP binding site [chemical binding]; other site
344609009597	Walker B motif; other site
344609009598	arginine finger; other site
344609009599	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
344609009600	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
344609009601	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
344609009602	intramembrane serine protease GlpG; Provisional; Region: PRK10907
344609009603	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
344609009604	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
344609009605	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
344609009606	active site residue [active]
344609009607	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
344609009608	hypothetical protein; Provisional; Region: PRK09781; cl08057
344609009609	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
344609009610	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609009611	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609009612	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
344609009613	ArsC family; Region: ArsC; pfam03960
344609009614	catalytic residues [active]
344609009615	arsenical pump membrane protein; Provisional; Region: PRK15445
344609009616	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
344609009617	transmembrane helices; other site
344609009618	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
344609009619	dimerization interface [polypeptide binding]; other site
344609009620	putative DNA binding site [nucleotide binding]; other site
344609009621	putative Zn2+ binding site [ion binding]; other site
344609009622	glutathione reductase; Validated; Region: PRK06116
344609009623	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
344609009624	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
344609009625	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
344609009626	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
344609009627	oligopeptidase A; Provisional; Region: PRK10911
344609009628	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
344609009629	active site
344609009630	Zn binding site [ion binding]; other site
344609009631	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609009632	S-adenosylmethionine binding site [chemical binding]; other site
344609009633	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
344609009634	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609009635	putative substrate translocation pore; other site
344609009636	POT family; Region: PTR2; pfam00854
344609009637	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
344609009638	Ligand Binding Site [chemical binding]; other site
344609009639	universal stress protein UspB; Provisional; Region: PRK04960
344609009640	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
344609009641	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
344609009642	Predicted flavoproteins [General function prediction only]; Region: COG2081
344609009643	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
344609009644	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609009645	HlyD family secretion protein; Region: HlyD; pfam00529
344609009646	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
344609009647	HlyD family secretion protein; Region: HlyD_3; pfam13437
344609009648	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
344609009649	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
344609009650	Walker A/P-loop; other site
344609009651	ATP binding site [chemical binding]; other site
344609009652	Q-loop/lid; other site
344609009653	ABC transporter signature motif; other site
344609009654	Walker B; other site
344609009655	D-loop; other site
344609009656	H-loop/switch region; other site
344609009657	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
344609009658	Walker A/P-loop; other site
344609009659	ATP binding site [chemical binding]; other site
344609009660	Q-loop/lid; other site
344609009661	ABC transporter signature motif; other site
344609009662	Walker B; other site
344609009663	D-loop; other site
344609009664	H-loop/switch region; other site
344609009665	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
344609009666	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
344609009667	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
344609009668	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
344609009669	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609009670	nickel responsive regulator; Provisional; Region: PRK02967
344609009671	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
344609009672	nickel transporter ATP-binding protein NikE; Provisional; Region: nikE; PRK10419
344609009673	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
344609009674	Walker A/P-loop; other site
344609009675	ATP binding site [chemical binding]; other site
344609009676	Q-loop/lid; other site
344609009677	ABC transporter signature motif; other site
344609009678	Walker B; other site
344609009679	D-loop; other site
344609009680	H-loop/switch region; other site
344609009681	nickel transporter ATP-binding protein NikD; Provisional; Region: nikD; PRK10418
344609009682	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
344609009683	Walker A/P-loop; other site
344609009684	ATP binding site [chemical binding]; other site
344609009685	Q-loop/lid; other site
344609009686	ABC transporter signature motif; other site
344609009687	Walker B; other site
344609009688	D-loop; other site
344609009689	H-loop/switch region; other site
344609009690	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
344609009691	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
344609009692	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609009693	dimer interface [polypeptide binding]; other site
344609009694	conserved gate region; other site
344609009695	putative PBP binding loops; other site
344609009696	ABC-ATPase subunit interface; other site
344609009697	nickel transporter permease NikB; Provisional; Region: PRK10352
344609009698	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609009699	dimer interface [polypeptide binding]; other site
344609009700	conserved gate region; other site
344609009701	putative PBP binding loops; other site
344609009702	ABC-ATPase subunit interface; other site
344609009703	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
344609009704	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
344609009705	substrate binding site [chemical binding]; other site
344609009706	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609009707	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609009708	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
344609009709	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
344609009710	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
344609009711	Domain of unknown function DUF20; Region: UPF0118; pfam01594
344609009712	major facilitator superfamily transporter; Provisional; Region: PRK05122
344609009713	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609009714	putative substrate translocation pore; other site
344609009715	hypothetical protein; Provisional; Region: PRK11615
344609009716	hypothetical protein; Provisional; Region: PRK11212
344609009717	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
344609009718	CPxP  motif; other site
344609009719	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
344609009720	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
344609009721	metal-binding site [ion binding]
344609009722	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
344609009723	Predicted membrane protein [Function unknown]; Region: COG3714
344609009724	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
344609009725	hypothetical protein; Provisional; Region: PRK10910
344609009726	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
344609009727	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609009728	S-adenosylmethionine binding site [chemical binding]; other site
344609009729	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
344609009730	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
344609009731	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
344609009732	P loop; other site
344609009733	GTP binding site [chemical binding]; other site
344609009734	cell division protein FtsE; Provisional; Region: PRK10908
344609009735	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609009736	Walker A/P-loop; other site
344609009737	ATP binding site [chemical binding]; other site
344609009738	Q-loop/lid; other site
344609009739	ABC transporter signature motif; other site
344609009740	Walker B; other site
344609009741	D-loop; other site
344609009742	H-loop/switch region; other site
344609009743	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
344609009744	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
344609009745	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
344609009746	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
344609009747	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
344609009748	DNA binding residues [nucleotide binding]
344609009749	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
344609009750	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
344609009751	dimerization interface [polypeptide binding]; other site
344609009752	ligand binding site [chemical binding]; other site
344609009753	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
344609009754	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
344609009755	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
344609009756	dimerization interface [polypeptide binding]; other site
344609009757	ligand binding site [chemical binding]; other site
344609009758	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
344609009759	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
344609009760	TM-ABC transporter signature motif; other site
344609009761	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
344609009762	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
344609009763	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
344609009764	TM-ABC transporter signature motif; other site
344609009765	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
344609009766	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
344609009767	Walker A/P-loop; other site
344609009768	ATP binding site [chemical binding]; other site
344609009769	Q-loop/lid; other site
344609009770	ABC transporter signature motif; other site
344609009771	Walker B; other site
344609009772	D-loop; other site
344609009773	H-loop/switch region; other site
344609009774	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
344609009775	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
344609009776	Walker A/P-loop; other site
344609009777	ATP binding site [chemical binding]; other site
344609009778	Q-loop/lid; other site
344609009779	ABC transporter signature motif; other site
344609009780	Walker B; other site
344609009781	D-loop; other site
344609009782	H-loop/switch region; other site
344609009783	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
344609009784	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
344609009785	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
344609009786	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
344609009787	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609009788	dimer interface [polypeptide binding]; other site
344609009789	conserved gate region; other site
344609009790	putative PBP binding loops; other site
344609009791	ABC-ATPase subunit interface; other site
344609009792	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
344609009793	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609009794	dimer interface [polypeptide binding]; other site
344609009795	conserved gate region; other site
344609009796	putative PBP binding loops; other site
344609009797	ABC-ATPase subunit interface; other site
344609009798	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
344609009799	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
344609009800	Walker A/P-loop; other site
344609009801	ATP binding site [chemical binding]; other site
344609009802	Q-loop/lid; other site
344609009803	ABC transporter signature motif; other site
344609009804	Walker B; other site
344609009805	D-loop; other site
344609009806	H-loop/switch region; other site
344609009807	TOBE domain; Region: TOBE_2; pfam08402
344609009808	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
344609009809	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
344609009810	putative active site [active]
344609009811	catalytic site [active]
344609009812	putative metal binding site [ion binding]; other site
344609009813	hypothetical protein; Provisional; Region: PRK10350
344609009814	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609009815	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609009816	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609009817	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609009818	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
344609009819	putative acetyltransferase YhhY; Provisional; Region: PRK10140
344609009820	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
344609009821	Coenzyme A binding pocket [chemical binding]; other site
344609009822	putative oxidoreductase; Provisional; Region: PRK10206
344609009823	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
344609009824	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
344609009825	Pirin-related protein [General function prediction only]; Region: COG1741
344609009826	Pirin; Region: Pirin; pfam02678
344609009827	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
344609009828	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
344609009829	DNA binding site [nucleotide binding]
344609009830	domain linker motif; other site
344609009831	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
344609009832	putative ligand binding site [chemical binding]; other site
344609009833	putative dimerization interface [polypeptide binding]; other site
344609009834	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
344609009835	ATP-binding site [chemical binding]; other site
344609009836	Gluconate-6-phosphate binding site [chemical binding]; other site
344609009837	Shikimate kinase; Region: SKI; pfam01202
344609009838	low affinity gluconate transporter; Provisional; Region: PRK10472
344609009839	gluconate transporter; Region: gntP; TIGR00791
344609009840	putative antibiotic transporter; Provisional; Region: PRK10739
344609009841	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
344609009842	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
344609009843	glycogen branching enzyme; Provisional; Region: PRK05402
344609009844	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
344609009845	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
344609009846	active site
344609009847	catalytic site [active]
344609009848	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
344609009849	glycogen debranching enzyme; Provisional; Region: PRK03705
344609009850	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
344609009851	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
344609009852	active site
344609009853	catalytic site [active]
344609009854	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
344609009855	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
344609009856	ligand binding site; other site
344609009857	oligomer interface; other site
344609009858	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
344609009859	sulfate 1 binding site; other site
344609009860	glycogen synthase; Provisional; Region: glgA; PRK00654
344609009861	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
344609009862	ADP-binding pocket [chemical binding]; other site
344609009863	homodimer interface [polypeptide binding]; other site
344609009864	glycogen phosphorylase; Provisional; Region: PRK14986
344609009865	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
344609009866	homodimer interface [polypeptide binding]; other site
344609009867	active site pocket [active]
344609009868	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609009869	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609009870	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609009871	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609009872	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609009873	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609009874	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609009875	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609009876	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609009877	HTH-like domain; Region: HTH_21; pfam13276
344609009878	Integrase core domain; Region: rve; pfam00665
344609009879	Integrase core domain; Region: rve_3; pfam13683
344609009880	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609009881	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
344609009882	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
344609009883	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
344609009884	DNA binding residues [nucleotide binding]
344609009885	dimerization interface [polypeptide binding]; other site
344609009886	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
344609009887	MgtC family; Region: MgtC; pfam02308
344609009888	acid-resistance protein; Provisional; Region: hdeB; PRK11566
344609009889	acid-resistance protein; Provisional; Region: PRK10208
344609009890	acid-resistance membrane protein; Provisional; Region: PRK10209
344609009891	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
344609009892	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
344609009893	pyruvate kinase; Provisional; Region: PRK05826
344609009894	multidrug efflux system protein MdtE; Provisional; Region: PRK09859
344609009895	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
344609009896	HlyD family secretion protein; Region: HlyD_3; pfam13437
344609009897	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
344609009898	Protein export membrane protein; Region: SecD_SecF; cl14618
344609009899	transcriptional regulator YdeO; Provisional; Region: PRK09940
344609009900	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609009901	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
344609009902	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609009903	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609009904	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
344609009905	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609009906	Haem-binding domain; Region: Haem_bd; pfam14376
344609009907	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
344609009908	trehalase; Provisional; Region: treF; PRK13270
344609009909	Trehalase; Region: Trehalase; pfam01204
344609009910	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
344609009911	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
344609009912	DNA binding residues [nucleotide binding]
344609009913	dimerization interface [polypeptide binding]; other site
344609009914	Transcriptional regulator [Transcription]; Region: LysR; COG0583
344609009915	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609009916	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
344609009917	putative effector binding pocket; other site
344609009918	putative dimerization interface [polypeptide binding]; other site
344609009919	inner membrane protein YhjD; Region: TIGR00766
344609009920	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609009921	metabolite-proton symporter; Region: 2A0106; TIGR00883
344609009922	putative substrate translocation pore; other site
344609009923	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
344609009924	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
344609009925	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
344609009926	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
344609009927	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
344609009928	substrate binding site [chemical binding]; other site
344609009929	ATP binding site [chemical binding]; other site
344609009930	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
344609009931	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
344609009932	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
344609009933	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
344609009934	putative diguanylate cyclase; Provisional; Region: PRK13561
344609009935	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
344609009936	metal binding site [ion binding]; metal-binding site
344609009937	active site
344609009938	I-site; other site
344609009939	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
344609009940	endo-1,4-D-glucanase; Provisional; Region: PRK11097
344609009941	cellulose synthase regulator protein; Provisional; Region: PRK11114
344609009942	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
344609009943	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
344609009944	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
344609009945	DXD motif; other site
344609009946	PilZ domain; Region: PilZ; pfam07238
344609009947	cell division protein; Provisional; Region: PRK10037
344609009948	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
344609009949	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609009950	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; cl17274
344609009951	DctM-like transporters; Region: DctM; pfam06808
344609009952	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
344609009953	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
344609009954	Transcriptional regulator [Transcription]; Region: IclR; COG1414
344609009955	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
344609009956	Bacterial transcriptional regulator; Region: IclR; pfam01614
344609009957	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
344609009958	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
344609009959	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
344609009960	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609009961	homodimer interface [polypeptide binding]; other site
344609009962	catalytic residue [active]
344609009963	alpha-amylase; Reviewed; Region: malS; PRK09505
344609009964	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
344609009965	active site
344609009966	catalytic site [active]
344609009967	hypothetical protein; Provisional; Region: PRK10356
344609009968	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
344609009969	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
344609009970	putative dimerization interface [polypeptide binding]; other site
344609009971	Transcriptional regulators [Transcription]; Region: PurR; COG1609
344609009972	putative ligand binding site [chemical binding]; other site
344609009973	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609009974	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
344609009975	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609009976	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
344609009977	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
344609009978	TM-ABC transporter signature motif; other site
344609009979	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
344609009980	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
344609009981	Walker A/P-loop; other site
344609009982	ATP binding site [chemical binding]; other site
344609009983	Q-loop/lid; other site
344609009984	ABC transporter signature motif; other site
344609009985	Walker B; other site
344609009986	D-loop; other site
344609009987	H-loop/switch region; other site
344609009988	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
344609009989	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
344609009990	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
344609009991	putative ligand binding site [chemical binding]; other site
344609009992	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609009993	Transposase; Region: HTH_Tnp_1; pfam01527
344609009994	putative transposase OrfB; Reviewed; Region: PHA02517
344609009995	Integrase core domain; Region: rve; pfam00665
344609009996	Integrase core domain; Region: rve_3; pfam13683
344609009997	xylose isomerase; Provisional; Region: PRK05474
344609009998	xylose isomerase; Region: xylose_isom_A; TIGR02630
344609009999	yiaA/B two helix domain; Region: YiaAB; pfam05360
344609010000	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010001	YsaB-like lipoprotein; Region: YsaB; pfam13983
344609010002	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
344609010003	dimer interface [polypeptide binding]; other site
344609010004	motif 1; other site
344609010005	active site
344609010006	motif 2; other site
344609010007	motif 3; other site
344609010008	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
344609010009	DALR anticodon binding domain; Region: DALR_1; pfam05746
344609010010	anticodon binding site; other site
344609010011	tRNA binding surface [nucleotide binding]; other site
344609010012	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010013	small toxic polypeptide; Provisional; Region: PRK09759
344609010014	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
344609010015	DNA-binding site [nucleotide binding]; DNA binding site
344609010016	RNA-binding motif; other site
344609010017	Predicted transcriptional regulator [Transcription]; Region: COG2944
344609010018	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
344609010019	non-specific DNA binding site [nucleotide binding]; other site
344609010020	salt bridge; other site
344609010021	sequence-specific DNA binding site [nucleotide binding]; other site
344609010022	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
344609010023	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
344609010024	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
344609010025	dimerization interface [polypeptide binding]; other site
344609010026	ligand binding site [chemical binding]; other site
344609010027	NADP binding site [chemical binding]; other site
344609010028	catalytic site [active]
344609010029	putative outer membrane lipoprotein; Provisional; Region: PRK10510
344609010030	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
344609010031	ligand binding site [chemical binding]; other site
344609010032	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
344609010033	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
344609010034	molybdopterin cofactor binding site [chemical binding]; other site
344609010035	substrate binding site [chemical binding]; other site
344609010036	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
344609010037	molybdopterin cofactor binding site; other site
344609010038	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
344609010039	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
344609010040	Coenzyme A binding pocket [chemical binding]; other site
344609010041	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
344609010042	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
344609010043	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
344609010044	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
344609010045	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609010046	putative substrate translocation pore; other site
344609010047	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010048	Fimbrial protein; Region: Fimbrial; cl01416
344609010049	long polar fimbrial protein LpfE; Provisional; Region: PRK15205
344609010050	phosphoethanolamine transferase; Provisional; Region: PRK11560
344609010051	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
344609010052	Sulfatase; Region: Sulfatase; pfam00884
344609010053	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
344609010054	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609010055	dimer interface [polypeptide binding]; other site
344609010056	conserved gate region; other site
344609010057	putative PBP binding loops; other site
344609010058	ABC-ATPase subunit interface; other site
344609010059	dipeptide transporter; Provisional; Region: PRK10913
344609010060	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
344609010061	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609010062	dimer interface [polypeptide binding]; other site
344609010063	conserved gate region; other site
344609010064	putative PBP binding loops; other site
344609010065	ABC-ATPase subunit interface; other site
344609010066	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
344609010067	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
344609010068	Walker A/P-loop; other site
344609010069	ATP binding site [chemical binding]; other site
344609010070	Q-loop/lid; other site
344609010071	ABC transporter signature motif; other site
344609010072	Walker B; other site
344609010073	D-loop; other site
344609010074	H-loop/switch region; other site
344609010075	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
344609010076	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
344609010077	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
344609010078	Walker A/P-loop; other site
344609010079	ATP binding site [chemical binding]; other site
344609010080	Q-loop/lid; other site
344609010081	ABC transporter signature motif; other site
344609010082	Walker B; other site
344609010083	D-loop; other site
344609010084	H-loop/switch region; other site
344609010085	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
344609010086	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
344609010087	serine transporter; Region: stp; TIGR00814
344609010088	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609010089	HTH-like domain; Region: HTH_21; pfam13276
344609010090	Integrase core domain; Region: rve; pfam00665
344609010091	Integrase core domain; Region: rve_3; pfam13683
344609010092	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
344609010093	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
344609010094	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609010095	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609010096	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609010097	Protein of unknown function (DUF3260); Region: DUF3260; cl11881
344609010098	celllulose biosynthesis operon protein BcsF/YhjT; Region: cellullose_BcsF; TIGR03493
344609010099	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
344609010100	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010101	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
344609010102	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
344609010103	NAD(P) binding site [chemical binding]; other site
344609010104	catalytic residues [active]
344609010105	putative alcohol dehydrogenase; Provisional; Region: PRK09860
344609010106	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
344609010107	dimer interface [polypeptide binding]; other site
344609010108	active site
344609010109	metal binding site [ion binding]; metal-binding site
344609010110	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
344609010111	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
344609010112	G1 box; other site
344609010113	putative GEF interaction site [polypeptide binding]; other site
344609010114	GTP/Mg2+ binding site [chemical binding]; other site
344609010115	Switch I region; other site
344609010116	G2 box; other site
344609010117	G3 box; other site
344609010118	Switch II region; other site
344609010119	G4 box; other site
344609010120	G5 box; other site
344609010121	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
344609010122	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
344609010123	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
344609010124	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
344609010125	selenocysteine synthase; Provisional; Region: PRK04311
344609010126	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
344609010127	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
344609010128	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
344609010129	catalytic residue [active]
344609010130	putative glutathione S-transferase; Provisional; Region: PRK10357
344609010131	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
344609010132	putative C-terminal domain interface [polypeptide binding]; other site
344609010133	putative GSH binding site (G-site) [chemical binding]; other site
344609010134	putative dimer interface [polypeptide binding]; other site
344609010135	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
344609010136	dimer interface [polypeptide binding]; other site
344609010137	N-terminal domain interface [polypeptide binding]; other site
344609010138	putative substrate binding pocket (H-site) [chemical binding]; other site
344609010139	PAAR motif; Region: PAAR_motif; cl15808
344609010140	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
344609010141	RHS Repeat; Region: RHS_repeat; pfam05593
344609010142	RHS Repeat; Region: RHS_repeat; pfam05593
344609010143	RHS Repeat; Region: RHS_repeat; pfam05593
344609010144	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
344609010145	RHS Repeat; Region: RHS_repeat; pfam05593
344609010146	RHS Repeat; Region: RHS_repeat; pfam05593
344609010147	RHS protein; Region: RHS; pfam03527
344609010148	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
344609010149	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010150	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
344609010151	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
344609010152	HlyD family secretion protein; Region: HlyD_3; pfam13437
344609010153	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
344609010154	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
344609010155	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
344609010156	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
344609010157	active site
344609010158	P-loop; other site
344609010159	phosphorylation site [posttranslational modification]
344609010160	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
344609010161	active site
344609010162	phosphorylation site [posttranslational modification]
344609010163	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
344609010164	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
344609010165	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
344609010166	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
344609010167	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
344609010168	hypothetical protein; Provisional; Region: PRK11020
344609010169	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010170	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
344609010171	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
344609010172	trimer interface [polypeptide binding]; other site
344609010173	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
344609010174	trimer interface [polypeptide binding]; other site
344609010175	Haemagglutinin; Region: HIM; pfam05662
344609010176	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609010177	HTH-like domain; Region: HTH_21; pfam13276
344609010178	Integrase core domain; Region: rve; pfam00665
344609010179	Integrase core domain; Region: rve_3; pfam13683
344609010180	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
344609010181	Haemagglutinin; Region: HIM; pfam05662
344609010182	Haemagglutinin; Region: HIM; pfam05662
344609010183	YadA-like C-terminal region; Region: YadA; pfam03895
344609010184	L-lactate permease; Provisional; Region: PRK10420
344609010185	glycolate transporter; Provisional; Region: PRK09695
344609010186	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
344609010187	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
344609010188	DNA-binding site [nucleotide binding]; DNA binding site
344609010189	FCD domain; Region: FCD; pfam07729
344609010190	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
344609010191	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
344609010192	phosphate binding site [ion binding]; other site
344609010193	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609010194	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609010195	putative rRNA methylase; Provisional; Region: PRK10358
344609010196	serine acetyltransferase; Provisional; Region: cysE; PRK11132
344609010197	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
344609010198	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
344609010199	trimer interface [polypeptide binding]; other site
344609010200	active site
344609010201	substrate binding site [chemical binding]; other site
344609010202	CoA binding site [chemical binding]; other site
344609010203	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
344609010204	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
344609010205	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
344609010206	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
344609010207	SecA binding site; other site
344609010208	Preprotein binding site; other site
344609010209	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
344609010210	GSH binding site [chemical binding]; other site
344609010211	catalytic residues [active]
344609010212	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
344609010213	active site residue [active]
344609010214	phosphoglyceromutase; Provisional; Region: PRK05434
344609010215	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
344609010216	AmiB activator; Provisional; Region: PRK11637
344609010217	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
344609010218	Peptidase family M23; Region: Peptidase_M23; pfam01551
344609010219	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
344609010220	NodB motif; other site
344609010221	putative active site [active]
344609010222	putative catalytic site [active]
344609010223	Zn binding site [ion binding]; other site
344609010224	putative glycosyl transferase; Provisional; Region: PRK10073
344609010225	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
344609010226	active site
344609010227	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
344609010228	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
344609010229	NAD(P) binding site [chemical binding]; other site
344609010230	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
344609010231	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
344609010232	substrate-cofactor binding pocket; other site
344609010233	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609010234	catalytic residue [active]
344609010235	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
344609010236	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
344609010237	NADP binding site [chemical binding]; other site
344609010238	homopentamer interface [polypeptide binding]; other site
344609010239	substrate binding site [chemical binding]; other site
344609010240	active site
344609010241	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
344609010242	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
344609010243	putative active site [active]
344609010244	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
344609010245	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
344609010246	putative active site [active]
344609010247	O-Antigen ligase; Region: Wzy_C; pfam04932
344609010248	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
344609010249	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
344609010250	active site
344609010251	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
344609010252	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
344609010253	Ligand binding site; other site
344609010254	metal-binding site
344609010255	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
344609010256	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; cl17526
344609010257	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
344609010258	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
344609010259	Ligand binding site; other site
344609010260	metal-binding site
344609010261	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
344609010262	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
344609010263	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
344609010264	Ligand binding site; other site
344609010265	metal-binding site
344609010266	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
344609010267	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
344609010268	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
344609010269	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
344609010270	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
344609010271	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
344609010272	putative active site [active]
344609010273	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
344609010274	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
344609010275	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
344609010276	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
344609010277	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
344609010278	active site
344609010279	(T/H)XGH motif; other site
344609010280	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
344609010281	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
344609010282	DNA binding site [nucleotide binding]
344609010283	catalytic residue [active]
344609010284	H2TH interface [polypeptide binding]; other site
344609010285	putative catalytic residues [active]
344609010286	turnover-facilitating residue; other site
344609010287	intercalation triad [nucleotide binding]; other site
344609010288	8OG recognition residue [nucleotide binding]; other site
344609010289	putative reading head residues; other site
344609010290	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
344609010291	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
344609010292	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
344609010293	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
344609010294	hypothetical protein; Reviewed; Region: PRK00024
344609010295	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
344609010296	MPN+ (JAMM) motif; other site
344609010297	Zinc-binding site [ion binding]; other site
344609010298	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
344609010299	Flavoprotein; Region: Flavoprotein; pfam02441
344609010300	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
344609010301	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
344609010302	trimer interface [polypeptide binding]; other site
344609010303	active site
344609010304	division inhibitor protein; Provisional; Region: slmA; PRK09480
344609010305	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
344609010306	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
344609010307	active site
344609010308	ribonuclease PH; Reviewed; Region: rph; PRK00173
344609010309	Ribonuclease PH; Region: RNase_PH_bact; cd11362
344609010310	hexamer interface [polypeptide binding]; other site
344609010311	active site
344609010312	hypothetical protein; Provisional; Region: PRK11820
344609010313	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
344609010314	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
344609010315	integrase; Provisional; Region: PRK09692
344609010316	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
344609010317	active site
344609010318	Int/Topo IB signature motif; other site
344609010319	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010320	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
344609010321	Ash protein family; Region: Phage_ASH; pfam10554
344609010322	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609010323	Transposase; Region: HTH_Tnp_1; pfam01527
344609010324	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases; Region: PFK; cl00204
344609010325	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
344609010326	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
344609010327	ssDNA binding site [nucleotide binding]; other site
344609010328	dimer interface [polypeptide binding]; other site
344609010329	tetramer (dimer of dimers) interface [polypeptide binding]; other site
344609010330	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
344609010331	DNA-damage-inducible protein D; Provisional; Region: dinD; PRK11525
344609010332	BRO family, N-terminal domain; Region: Bro-N; pfam02498
344609010333	Predicted membrane protein [Function unknown]; Region: COG2860
344609010334	UPF0126 domain; Region: UPF0126; pfam03458
344609010335	UPF0126 domain; Region: UPF0126; pfam03458
344609010336	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
344609010337	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
344609010338	catalytic site [active]
344609010339	G-X2-G-X-G-K; other site
344609010340	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
344609010341	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
344609010342	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
344609010343	Zn2+ binding site [ion binding]; other site
344609010344	Mg2+ binding site [ion binding]; other site
344609010345	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
344609010346	synthetase active site [active]
344609010347	NTP binding site [chemical binding]; other site
344609010348	metal binding site [ion binding]; metal-binding site
344609010349	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
344609010350	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
344609010351	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
344609010352	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
344609010353	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
344609010354	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
344609010355	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
344609010356	generic binding surface II; other site
344609010357	ssDNA binding site; other site
344609010358	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
344609010359	ATP binding site [chemical binding]; other site
344609010360	putative Mg++ binding site [ion binding]; other site
344609010361	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
344609010362	nucleotide binding region [chemical binding]; other site
344609010363	ATP-binding site [chemical binding]; other site
344609010364	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
344609010365	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
344609010366	AsmA family; Region: AsmA; pfam05170
344609010367	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
344609010368	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
344609010369	putative alpha-glucosidase; Provisional; Region: PRK10658
344609010370	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
344609010371	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
344609010372	active site
344609010373	homotrimer interface [polypeptide binding]; other site
344609010374	catalytic site [active]
344609010375	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
344609010376	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
344609010377	putative transporter; Provisional; Region: PRK11462
344609010378	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010379	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609010380	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609010381	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609010382	sugar efflux transporter; Region: 2A0120; TIGR00899
344609010383	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609010384	putative substrate translocation pore; other site
344609010385	EamA-like transporter family; Region: EamA; pfam00892
344609010386	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
344609010387	EamA-like transporter family; Region: EamA; pfam00892
344609010388	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
344609010389	lipoprotein, YaeC family; Region: TIGR00363
344609010390	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010391	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
344609010392	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
344609010393	FeS/SAM binding site; other site
344609010394	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
344609010395	putative transport protein YifK; Provisional; Region: PRK10746
344609010396	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
344609010397	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
344609010398	putative common antigen polymerase; Provisional; Region: PRK02975
344609010399	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
344609010400	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
344609010401	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
344609010402	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
344609010403	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
344609010404	inhibitor-cofactor binding pocket; inhibition site
344609010405	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609010406	catalytic residue [active]
344609010407	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
344609010408	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
344609010409	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
344609010410	substrate binding site; other site
344609010411	tetramer interface; other site
344609010412	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
344609010413	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
344609010414	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
344609010415	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
344609010416	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
344609010417	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
344609010418	active site
344609010419	homodimer interface [polypeptide binding]; other site
344609010420	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
344609010421	Chain length determinant protein; Region: Wzz; pfam02706
344609010422	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
344609010423	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
344609010424	Mg++ binding site [ion binding]; other site
344609010425	putative catalytic motif [active]
344609010426	substrate binding site [chemical binding]; other site
344609010427	transcription termination factor Rho; Provisional; Region: rho; PRK09376
344609010428	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
344609010429	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
344609010430	RNA binding site [nucleotide binding]; other site
344609010431	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
344609010432	multimer interface [polypeptide binding]; other site
344609010433	Walker A motif; other site
344609010434	ATP binding site [chemical binding]; other site
344609010435	Walker B motif; other site
344609010436	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
344609010437	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
344609010438	catalytic residues [active]
344609010439	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
344609010440	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
344609010441	ATP binding site [chemical binding]; other site
344609010442	Mg++ binding site [ion binding]; other site
344609010443	motif III; other site
344609010444	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
344609010445	nucleotide binding region [chemical binding]; other site
344609010446	ATP-binding site [chemical binding]; other site
344609010447	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
344609010448	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
344609010449	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
344609010450	Part of AAA domain; Region: AAA_19; pfam13245
344609010451	Family description; Region: UvrD_C_2; pfam13538
344609010452	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609010453	HTH-like domain; Region: HTH_21; pfam13276
344609010454	Integrase core domain; Region: rve; pfam00665
344609010455	Integrase core domain; Region: rve_3; pfam13683
344609010456	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
344609010457	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
344609010458	ketol-acid reductoisomerase; Validated; Region: PRK05225
344609010459	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
344609010460	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
344609010461	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
344609010462	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609010463	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
344609010464	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
344609010465	putative dimerization interface [polypeptide binding]; other site
344609010466	threonine dehydratase; Reviewed; Region: PRK09224
344609010467	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
344609010468	tetramer interface [polypeptide binding]; other site
344609010469	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609010470	catalytic residue [active]
344609010471	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
344609010472	putative Ile/Val binding site [chemical binding]; other site
344609010473	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
344609010474	putative Ile/Val binding site [chemical binding]; other site
344609010475	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
344609010476	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
344609010477	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
344609010478	homodimer interface [polypeptide binding]; other site
344609010479	substrate-cofactor binding pocket; other site
344609010480	catalytic residue [active]
344609010481	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
344609010482	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
344609010483	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
344609010484	PYR/PP interface [polypeptide binding]; other site
344609010485	dimer interface [polypeptide binding]; other site
344609010486	TPP binding site [chemical binding]; other site
344609010487	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
344609010488	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
344609010489	TPP-binding site [chemical binding]; other site
344609010490	dimer interface [polypeptide binding]; other site
344609010491	putative ATP-dependent protease; Provisional; Region: PRK09862
344609010492	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
344609010493	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609010494	Walker A motif; other site
344609010495	ATP binding site [chemical binding]; other site
344609010496	Walker B motif; other site
344609010497	arginine finger; other site
344609010498	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
344609010499	hypothetical protein; Provisional; Region: PRK11027
344609010500	transcriptional regulator HdfR; Provisional; Region: PRK03601
344609010501	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609010502	LysR substrate binding domain; Region: LysR_substrate; pfam03466
344609010503	dimerization interface [polypeptide binding]; other site
344609010504	Transcriptional regulators [Transcription]; Region: FadR; COG2186
344609010505	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
344609010506	DNA-binding site [nucleotide binding]; DNA binding site
344609010507	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
344609010508	putative transporter; Provisional; Region: PRK10504
344609010509	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609010510	putative substrate translocation pore; other site
344609010511	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609010512	transcriptional repressor RbsR; Provisional; Region: PRK10423
344609010513	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
344609010514	DNA binding site [nucleotide binding]
344609010515	domain linker motif; other site
344609010516	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
344609010517	dimerization interface [polypeptide binding]; other site
344609010518	ligand binding site [chemical binding]; other site
344609010519	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
344609010520	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
344609010521	substrate binding site [chemical binding]; other site
344609010522	dimer interface [polypeptide binding]; other site
344609010523	ATP binding site [chemical binding]; other site
344609010524	D-ribose pyranase; Provisional; Region: PRK11797
344609010525	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
344609010526	potassium uptake protein; Region: kup; TIGR00794
344609010527	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609010528	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609010529	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609010530	regulatory ATPase RavA; Provisional; Region: PRK13531
344609010531	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609010532	Walker A motif; other site
344609010533	ATP binding site [chemical binding]; other site
344609010534	Walker B motif; other site
344609010535	arginine finger; other site
344609010536	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
344609010537	hypothetical protein; Provisional; Region: yieM; PRK10997
344609010538	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
344609010539	metal ion-dependent adhesion site (MIDAS); other site
344609010540	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
344609010541	dimer interface [polypeptide binding]; other site
344609010542	active site
344609010543	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
344609010544	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
344609010545	putative DNA binding site [nucleotide binding]; other site
344609010546	putative Zn2+ binding site [ion binding]; other site
344609010547	AsnC family; Region: AsnC_trans_reg; pfam01037
344609010548	FMN-binding protein MioC; Provisional; Region: PRK09004
344609010549	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
344609010550	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
344609010551	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
344609010552	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
344609010553	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609010554	S-adenosylmethionine binding site [chemical binding]; other site
344609010555	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
344609010556	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
344609010557	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
344609010558	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
344609010559	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
344609010560	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
344609010561	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
344609010562	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
344609010563	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
344609010564	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
344609010565	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
344609010566	beta subunit interaction interface [polypeptide binding]; other site
344609010567	Walker A motif; other site
344609010568	ATP binding site [chemical binding]; other site
344609010569	Walker B motif; other site
344609010570	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
344609010571	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
344609010572	core domain interface [polypeptide binding]; other site
344609010573	delta subunit interface [polypeptide binding]; other site
344609010574	epsilon subunit interface [polypeptide binding]; other site
344609010575	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
344609010576	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
344609010577	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
344609010578	alpha subunit interaction interface [polypeptide binding]; other site
344609010579	Walker A motif; other site
344609010580	ATP binding site [chemical binding]; other site
344609010581	Walker B motif; other site
344609010582	inhibitor binding site; inhibition site
344609010583	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
344609010584	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
344609010585	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
344609010586	gamma subunit interface [polypeptide binding]; other site
344609010587	epsilon subunit interface [polypeptide binding]; other site
344609010588	LBP interface [polypeptide binding]; other site
344609010589	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
344609010590	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
344609010591	Substrate binding site; other site
344609010592	Mg++ binding site; other site
344609010593	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
344609010594	active site
344609010595	substrate binding site [chemical binding]; other site
344609010596	CoA binding site [chemical binding]; other site
344609010597	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
344609010598	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
344609010599	glutaminase active site [active]
344609010600	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
344609010601	dimer interface [polypeptide binding]; other site
344609010602	active site
344609010603	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
344609010604	dimer interface [polypeptide binding]; other site
344609010605	active site
344609010606	fimbrial protein; Provisional; Region: lpfA; PRK15289
344609010607	fimbrial chaperone protein; Provisional; Region: lfpB; PRK15290
344609010608	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
344609010609	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
344609010610	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
344609010611	PapC N-terminal domain; Region: PapC_N; pfam13954
344609010612	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609010613	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609010614	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609010615	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609010616	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609010617	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609010618	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609010619	Fimbrial protein; Region: Fimbrial; cl01416
344609010620	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
344609010621	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
344609010622	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609010623	dimer interface [polypeptide binding]; other site
344609010624	conserved gate region; other site
344609010625	putative PBP binding loops; other site
344609010626	ABC-ATPase subunit interface; other site
344609010627	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
344609010628	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609010629	dimer interface [polypeptide binding]; other site
344609010630	conserved gate region; other site
344609010631	putative PBP binding loops; other site
344609010632	ABC-ATPase subunit interface; other site
344609010633	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
344609010634	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
344609010635	Walker A/P-loop; other site
344609010636	ATP binding site [chemical binding]; other site
344609010637	Q-loop/lid; other site
344609010638	ABC transporter signature motif; other site
344609010639	Walker B; other site
344609010640	D-loop; other site
344609010641	H-loop/switch region; other site
344609010642	transcriptional regulator PhoU; Provisional; Region: PRK11115
344609010643	PhoU domain; Region: PhoU; pfam01895
344609010644	PhoU domain; Region: PhoU; pfam01895
344609010645	CAT RNA binding domain; Region: CAT_RBD; pfam03123
344609010646	PRD domain; Region: PRD; pfam00874
344609010647	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010648	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
344609010649	Predicted flavoprotein [General function prediction only]; Region: COG0431
344609010650	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
344609010651	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
344609010652	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
344609010653	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609010654	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
344609010655	substrate binding pocket [chemical binding]; other site
344609010656	dimerization interface [polypeptide binding]; other site
344609010657	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
344609010658	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609010659	putative substrate translocation pore; other site
344609010660	tryptophan permease TnaB; Provisional; Region: PRK09664
344609010661	aromatic amino acid transport protein; Region: araaP; TIGR00837
344609010662	tryptophanase, leader peptide-associated; Region: tnaA_trp_ase; TIGR02617
344609010663	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
344609010664	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
344609010665	catalytic residue [active]
344609010666	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010667	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010668	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
344609010669	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
344609010670	trmE is a tRNA modification GTPase; Region: trmE; cd04164
344609010671	G1 box; other site
344609010672	GTP/Mg2+ binding site [chemical binding]; other site
344609010673	Switch I region; other site
344609010674	G2 box; other site
344609010675	Switch II region; other site
344609010676	G3 box; other site
344609010677	G4 box; other site
344609010678	G5 box; other site
344609010679	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
344609010680	membrane protein insertase; Provisional; Region: PRK01318
344609010681	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
344609010682	ribonuclease P; Reviewed; Region: rnpA; PRK01732
344609010683	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
344609010684	DnaA N-terminal domain; Region: DnaA_N; pfam11638
344609010685	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
344609010686	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609010687	Walker A motif; other site
344609010688	ATP binding site [chemical binding]; other site
344609010689	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
344609010690	Walker B motif; other site
344609010691	arginine finger; other site
344609010692	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
344609010693	DnaA box-binding interface [nucleotide binding]; other site
344609010694	DNA polymerase III subunit beta; Validated; Region: PRK05643
344609010695	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
344609010696	putative DNA binding surface [nucleotide binding]; other site
344609010697	dimer interface [polypeptide binding]; other site
344609010698	beta-clamp/clamp loader binding surface; other site
344609010699	beta-clamp/translesion DNA polymerase binding surface; other site
344609010700	recF protein; Region: recf; TIGR00611
344609010701	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609010702	Walker A/P-loop; other site
344609010703	ATP binding site [chemical binding]; other site
344609010704	Q-loop/lid; other site
344609010705	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609010706	ABC transporter signature motif; other site
344609010707	Walker B; other site
344609010708	D-loop; other site
344609010709	H-loop/switch region; other site
344609010710	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
344609010711	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609010712	Mg2+ binding site [ion binding]; other site
344609010713	G-X-G motif; other site
344609010714	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
344609010715	anchoring element; other site
344609010716	dimer interface [polypeptide binding]; other site
344609010717	ATP binding site [chemical binding]; other site
344609010718	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
344609010719	active site
344609010720	putative metal-binding site [ion binding]; other site
344609010721	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
344609010722	hypothetical protein; Provisional; Region: PRK11426
344609010723	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609010724	active site
344609010725	motif I; other site
344609010726	motif II; other site
344609010727	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
344609010728	Putative transposase; Region: Y2_Tnp; pfam04986
344609010729	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
344609010730	hypothetical protein; Provisional; Region: PRK11616
344609010731	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
344609010732	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
344609010733	putative dimer interface [polypeptide binding]; other site
344609010734	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
344609010735	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
344609010736	putative dimer interface [polypeptide binding]; other site
344609010737	putative transporter; Validated; Region: PRK03818
344609010738	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
344609010739	TrkA-C domain; Region: TrkA_C; pfam02080
344609010740	TrkA-C domain; Region: TrkA_C; pfam02080
344609010741	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
344609010742	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
344609010743	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
344609010744	DNA-binding site [nucleotide binding]; DNA binding site
344609010745	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
344609010746	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
344609010747	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
344609010748	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
344609010749	active site turn [active]
344609010750	phosphorylation site [posttranslational modification]
344609010751	Predicted membrane protein [Function unknown]; Region: COG2149
344609010752	Domain of unknown function (DUF202); Region: DUF202; pfam02656
344609010753	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
344609010754	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
344609010755	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609010756	putative substrate translocation pore; other site
344609010757	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
344609010758	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
344609010759	PYR/PP interface [polypeptide binding]; other site
344609010760	dimer interface [polypeptide binding]; other site
344609010761	TPP binding site [chemical binding]; other site
344609010762	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
344609010763	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
344609010764	TPP-binding site [chemical binding]; other site
344609010765	dimer interface [polypeptide binding]; other site
344609010766	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
344609010767	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
344609010768	putative valine binding site [chemical binding]; other site
344609010769	dimer interface [polypeptide binding]; other site
344609010770	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
344609010771	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609010772	active site
344609010773	phosphorylation site [posttranslational modification]
344609010774	intermolecular recognition site; other site
344609010775	dimerization interface [polypeptide binding]; other site
344609010776	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
344609010777	DNA binding residues [nucleotide binding]
344609010778	dimerization interface [polypeptide binding]; other site
344609010779	sensory histidine kinase UhpB; Provisional; Region: PRK11644
344609010780	MASE1; Region: MASE1; pfam05231
344609010781	Histidine kinase; Region: HisKA_3; pfam07730
344609010782	regulatory protein UhpC; Provisional; Region: PRK11663
344609010783	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609010784	putative substrate translocation pore; other site
344609010785	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
344609010786	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609010787	putative substrate translocation pore; other site
344609010788	cryptic adenine deaminase; Provisional; Region: PRK10027
344609010789	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
344609010790	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
344609010791	active site
344609010792	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
344609010793	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
344609010794	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
344609010795	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010796	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
344609010797	HemY protein N-terminus; Region: HemY_N; pfam07219
344609010798	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
344609010799	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
344609010800	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
344609010801	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
344609010802	active site
344609010803	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
344609010804	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
344609010805	domain interfaces; other site
344609010806	active site
344609010807	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
344609010808	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
344609010809	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
344609010810	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
344609010811	putative iron binding site [ion binding]; other site
344609010812	hypothetical protein; Provisional; Region: PRK09807
344609010813	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
344609010814	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
344609010815	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
344609010816	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
344609010817	hypothetical protein; Provisional; Region: PRK10963
344609010818	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
344609010819	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
344609010820	active site
344609010821	DNA binding site [nucleotide binding]
344609010822	Int/Topo IB signature motif; other site
344609010823	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
344609010824	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609010825	motif II; other site
344609010826	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
344609010827	Part of AAA domain; Region: AAA_19; pfam13245
344609010828	Family description; Region: UvrD_C_2; pfam13538
344609010829	Uncharacterized conserved protein [Function unknown]; Region: COG1912
344609010830	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010831	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609010832	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609010833	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609010834	Predicted periplasmic protein [Function unknown]; Region: COG3698
344609010835	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
344609010836	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
344609010837	Cl binding site [ion binding]; other site
344609010838	oligomer interface [polypeptide binding]; other site
344609010839	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010840	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010841	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
344609010842	EamA-like transporter family; Region: EamA; cl17759
344609010843	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
344609010844	CoenzymeA binding site [chemical binding]; other site
344609010845	subunit interaction site [polypeptide binding]; other site
344609010846	PHB binding site; other site
344609010847	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
344609010848	dimerization interface [polypeptide binding]; other site
344609010849	substrate binding site [chemical binding]; other site
344609010850	active site
344609010851	calcium binding site [ion binding]; other site
344609010852	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
344609010853	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
344609010854	ATP binding site [chemical binding]; other site
344609010855	putative Mg++ binding site [ion binding]; other site
344609010856	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
344609010857	nucleotide binding region [chemical binding]; other site
344609010858	ATP-binding site [chemical binding]; other site
344609010859	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
344609010860	Helicase and RNase D C-terminal; Region: HRDC; smart00341
344609010861	threonine efflux system; Provisional; Region: PRK10229
344609010862	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
344609010863	lysophospholipase L2; Provisional; Region: PRK10749
344609010864	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
344609010865	putative hydrolase; Provisional; Region: PRK10976
344609010866	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609010867	active site
344609010868	motif I; other site
344609010869	motif II; other site
344609010870	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609010871	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
344609010872	EamA-like transporter family; Region: EamA; pfam00892
344609010873	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
344609010874	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
344609010875	THF binding site; other site
344609010876	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
344609010877	substrate binding site [chemical binding]; other site
344609010878	THF binding site; other site
344609010879	zinc-binding site [ion binding]; other site
344609010880	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609010881	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609010882	HTH-like domain; Region: HTH_21; pfam13276
344609010883	Integrase core domain; Region: rve; pfam00665
344609010884	Integrase core domain; Region: rve_3; pfam13683
344609010885	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
344609010886	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
344609010887	uridine phosphorylase; Provisional; Region: PRK11178
344609010888	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
344609010889	DNA recombination protein RmuC; Provisional; Region: PRK10361
344609010890	RmuC family; Region: RmuC; pfam02646
344609010891	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
344609010892	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609010893	S-adenosylmethionine binding site [chemical binding]; other site
344609010894	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
344609010895	SCP-2 sterol transfer family; Region: SCP2; pfam02036
344609010896	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
344609010897	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
344609010898	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
344609010899	twin arginine translocase protein A; Provisional; Region: tatA; PRK00575
344609010900	sec-independent translocase; Provisional; Region: PRK01770
344609010901	sec-independent translocase; Provisional; Region: tatB; PRK00404
344609010902	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
344609010903	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
344609010904	active site
344609010905	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
344609010906	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
344609010907	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
344609010908	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
344609010909	FMN reductase; Validated; Region: fre; PRK08051
344609010910	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
344609010911	FAD binding pocket [chemical binding]; other site
344609010912	FAD binding motif [chemical binding]; other site
344609010913	phosphate binding motif [ion binding]; other site
344609010914	beta-alpha-beta structure motif; other site
344609010915	NAD binding pocket [chemical binding]; other site
344609010916	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
344609010917	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
344609010918	dimer interface [polypeptide binding]; other site
344609010919	active site
344609010920	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
344609010921	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
344609010922	substrate binding site [chemical binding]; other site
344609010923	oxyanion hole (OAH) forming residues; other site
344609010924	trimer interface [polypeptide binding]; other site
344609010925	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
344609010926	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
344609010927	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
344609010928	proline dipeptidase; Provisional; Region: PRK13607
344609010929	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
344609010930	active site
344609010931	hypothetical protein; Provisional; Region: PRK11568
344609010932	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
344609010933	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
344609010934	potassium transporter; Provisional; Region: PRK10750
344609010935	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
344609010936	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
344609010937	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
344609010938	Walker A motif; other site
344609010939	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
344609010940	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
344609010941	GTP binding site; other site
344609010942	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
344609010943	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
344609010944	serine/threonine protein kinase; Provisional; Region: PRK11768
344609010945	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
344609010946	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
344609010947	catalytic residues [active]
344609010948	hinge region; other site
344609010949	alpha helical domain; other site
344609010950	hypothetical protein; Provisional; Region: PRK11367
344609010951	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
344609010952	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
344609010953	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
344609010954	putative acyl-acceptor binding pocket; other site
344609010955	DNA polymerase I; Provisional; Region: PRK05755
344609010956	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
344609010957	active site
344609010958	metal binding site 1 [ion binding]; metal-binding site
344609010959	putative 5' ssDNA interaction site; other site
344609010960	metal binding site 3; metal-binding site
344609010961	metal binding site 2 [ion binding]; metal-binding site
344609010962	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
344609010963	putative DNA binding site [nucleotide binding]; other site
344609010964	putative metal binding site [ion binding]; other site
344609010965	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
344609010966	active site
344609010967	catalytic site [active]
344609010968	substrate binding site [chemical binding]; other site
344609010969	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
344609010970	active site
344609010971	DNA binding site [nucleotide binding]
344609010972	catalytic site [active]
344609010973	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
344609010974	G1 box; other site
344609010975	GTP/Mg2+ binding site [chemical binding]; other site
344609010976	Switch I region; other site
344609010977	G2 box; other site
344609010978	G3 box; other site
344609010979	Switch II region; other site
344609010980	G4 box; other site
344609010981	G5 box; other site
344609010982	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
344609010983	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
344609010984	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
344609010985	FeS/SAM binding site; other site
344609010986	HemN C-terminal domain; Region: HemN_C; pfam06969
344609010987	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
344609010988	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609010989	active site
344609010990	phosphorylation site [posttranslational modification]
344609010991	intermolecular recognition site; other site
344609010992	dimerization interface [polypeptide binding]; other site
344609010993	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609010994	Walker A motif; other site
344609010995	ATP binding site [chemical binding]; other site
344609010996	Walker B motif; other site
344609010997	arginine finger; other site
344609010998	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
344609010999	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
344609011000	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
344609011001	putative active site [active]
344609011002	heme pocket [chemical binding]; other site
344609011003	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609011004	dimer interface [polypeptide binding]; other site
344609011005	phosphorylation site [posttranslational modification]
344609011006	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609011007	ATP binding site [chemical binding]; other site
344609011008	Mg2+ binding site [ion binding]; other site
344609011009	G-X-G motif; other site
344609011010	glutamine synthetase; Provisional; Region: glnA; PRK09469
344609011011	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
344609011012	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
344609011013	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
344609011014	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
344609011015	G1 box; other site
344609011016	putative GEF interaction site [polypeptide binding]; other site
344609011017	GTP/Mg2+ binding site [chemical binding]; other site
344609011018	Switch I region; other site
344609011019	G2 box; other site
344609011020	G3 box; other site
344609011021	Switch II region; other site
344609011022	G4 box; other site
344609011023	G5 box; other site
344609011024	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
344609011025	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
344609011026	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
344609011027	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
344609011028	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
344609011029	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
344609011030	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
344609011031	substrate binding site [chemical binding]; other site
344609011032	ATP binding site [chemical binding]; other site
344609011033	Class I aldolases; Region: Aldolase_Class_I; cl17187
344609011034	catalytic residue [active]
344609011035	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
344609011036	putative oxidoreductase; Provisional; Region: PRK10083
344609011037	NAD(P) binding site [chemical binding]; other site
344609011038	Integrase core domain; Region: rve_3; pfam13683
344609011039	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609011040	HTH-like domain; Region: HTH_21; pfam13276
344609011041	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011042	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
344609011043	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
344609011044	active site
344609011045	catalytic residues [active]
344609011046	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
344609011047	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609011048	motif II; other site
344609011049	hypothetical protein; Reviewed; Region: PRK01637
344609011050	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
344609011051	putative active site [active]
344609011052	dimerization interface [polypeptide binding]; other site
344609011053	putative tRNAtyr binding site [nucleotide binding]; other site
344609011054	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
344609011055	Coenzyme A binding pocket [chemical binding]; other site
344609011056	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
344609011057	putative transposase OrfB; Reviewed; Region: PHA02517
344609011058	Integrase core domain; Region: rve; pfam00665
344609011059	Integrase core domain; Region: rve_3; pfam13683
344609011060	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609011061	Transposase; Region: HTH_Tnp_1; pfam01527
344609011062	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
344609011063	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
344609011064	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
344609011065	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
344609011066	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
344609011067	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
344609011068	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
344609011069	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
344609011070	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
344609011071	active site
344609011072	phosphorylation site [posttranslational modification]
344609011073	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011074	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
344609011075	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
344609011076	nucleotide binding site [chemical binding]; other site
344609011077	active site
344609011078	rhamnulose-1-phosphate aldolase; Provisional; Region: PRK03634
344609011079	Zn2+ binding site [ion binding]; other site
344609011080	intersubunit interface [polypeptide binding]; other site
344609011081	transcriptional activator RhaS; Provisional; Region: PRK13503
344609011082	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
344609011083	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609011084	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609011085	transcriptional activator RhaR; Provisional; Region: PRK13500
344609011086	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
344609011087	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609011088	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609011089	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
344609011090	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
344609011091	superoxide dismutase; Provisional; Region: PRK10925
344609011092	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
344609011093	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
344609011094	2-keto-3-deoxygluconate permease; Region: KdgT; cl14653
344609011095	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
344609011096	MOSC domain; Region: MOSC; pfam03473
344609011097	3-alpha domain; Region: 3-alpha; pfam03475
344609011098	two-component sensor protein; Provisional; Region: cpxA; PRK09470
344609011099	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
344609011100	dimerization interface [polypeptide binding]; other site
344609011101	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609011102	dimer interface [polypeptide binding]; other site
344609011103	phosphorylation site [posttranslational modification]
344609011104	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609011105	ATP binding site [chemical binding]; other site
344609011106	Mg2+ binding site [ion binding]; other site
344609011107	G-X-G motif; other site
344609011108	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
344609011109	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609011110	active site
344609011111	intermolecular recognition site; other site
344609011112	dimerization interface [polypeptide binding]; other site
344609011113	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
344609011114	DNA binding site [nucleotide binding]
344609011115	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
344609011116	dimer interface [polypeptide binding]; other site
344609011117	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
344609011118	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
344609011119	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
344609011120	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
344609011121	active site
344609011122	ADP/pyrophosphate binding site [chemical binding]; other site
344609011123	dimerization interface [polypeptide binding]; other site
344609011124	allosteric effector site; other site
344609011125	fructose-1,6-bisphosphate binding site; other site
344609011126	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
344609011127	sulfate transporter subunit; Provisional; Region: PRK10752
344609011128	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
344609011129	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
344609011130	triosephosphate isomerase; Provisional; Region: PRK14567
344609011131	substrate binding site [chemical binding]; other site
344609011132	dimer interface [polypeptide binding]; other site
344609011133	catalytic triad [active]
344609011134	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
344609011135	Predicted membrane protein [Function unknown]; Region: COG3152
344609011136	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609011137	Transposase; Region: HTH_Tnp_1; pfam01527
344609011138	putative transposase OrfB; Reviewed; Region: PHA02517
344609011139	Integrase core domain; Region: rve; pfam00665
344609011140	Integrase core domain; Region: rve_3; pfam13683
344609011141	hypothetical protein; Provisional; Region: PRK09981
344609011142	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
344609011143	Ligand Binding Site [chemical binding]; other site
344609011144	ferredoxin-NADP reductase; Provisional; Region: PRK10926
344609011145	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
344609011146	FAD binding pocket [chemical binding]; other site
344609011147	FAD binding motif [chemical binding]; other site
344609011148	phosphate binding motif [ion binding]; other site
344609011149	beta-alpha-beta structure motif; other site
344609011150	NAD binding pocket [chemical binding]; other site
344609011151	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
344609011152	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
344609011153	putative active site [active]
344609011154	glycerol kinase; Provisional; Region: glpK; PRK00047
344609011155	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
344609011156	N- and C-terminal domain interface [polypeptide binding]; other site
344609011157	active site
344609011158	MgATP binding site [chemical binding]; other site
344609011159	catalytic site [active]
344609011160	metal binding site [ion binding]; metal-binding site
344609011161	glycerol binding site [chemical binding]; other site
344609011162	homotetramer interface [polypeptide binding]; other site
344609011163	homodimer interface [polypeptide binding]; other site
344609011164	FBP binding site [chemical binding]; other site
344609011165	protein IIAGlc interface [polypeptide binding]; other site
344609011166	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
344609011167	amphipathic channel; other site
344609011168	Asn-Pro-Ala signature motifs; other site
344609011169	septal ring assembly protein ZapB; Provisional; Region: PRK15422
344609011170	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
344609011171	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
344609011172	UbiA prenyltransferase family; Region: UbiA; pfam01040
344609011173	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
344609011174	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609011175	Walker A motif; other site
344609011176	ATP binding site [chemical binding]; other site
344609011177	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
344609011178	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
344609011179	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
344609011180	active site
344609011181	HslU subunit interaction site [polypeptide binding]; other site
344609011182	essential cell division protein FtsN; Provisional; Region: PRK10927
344609011183	cell division protein FtsN; Provisional; Region: PRK12757
344609011184	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
344609011185	DNA binding site [nucleotide binding]
344609011186	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
344609011187	domain linker motif; other site
344609011188	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
344609011189	dimerization interface [polypeptide binding]; other site
344609011190	ligand binding site [chemical binding]; other site
344609011191	primosome assembly protein PriA; Validated; Region: PRK05580
344609011192	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
344609011193	ATP binding site [chemical binding]; other site
344609011194	putative Mg++ binding site [ion binding]; other site
344609011195	helicase superfamily c-terminal domain; Region: HELICc; smart00490
344609011196	ATP-binding site [chemical binding]; other site
344609011197	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
344609011198	hypothetical protein; Provisional; Region: PRK10030
344609011199	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
344609011200	dimerization interface [polypeptide binding]; other site
344609011201	DNA binding site [nucleotide binding]
344609011202	corepressor binding sites; other site
344609011203	cystathionine gamma-synthase; Provisional; Region: PRK08045
344609011204	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
344609011205	homodimer interface [polypeptide binding]; other site
344609011206	substrate-cofactor binding pocket; other site
344609011207	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609011208	catalytic residue [active]
344609011209	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
344609011210	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
344609011211	putative catalytic residues [active]
344609011212	putative nucleotide binding site [chemical binding]; other site
344609011213	putative aspartate binding site [chemical binding]; other site
344609011214	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
344609011215	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
344609011216	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
344609011217	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
344609011218	FAD binding site [chemical binding]; other site
344609011219	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
344609011220	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
344609011221	heme binding site [chemical binding]; other site
344609011222	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
344609011223	EamA-like transporter family; Region: EamA; pfam00892
344609011224	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
344609011225	EamA-like transporter family; Region: EamA; pfam00892
344609011226	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
344609011227	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
344609011228	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
344609011229	dimer interface [polypeptide binding]; other site
344609011230	active site
344609011231	metal binding site [ion binding]; metal-binding site
344609011232	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
344609011233	active site
344609011234	intersubunit interactions; other site
344609011235	catalytic residue [active]
344609011236	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
344609011237	dimerization domain swap beta strand [polypeptide binding]; other site
344609011238	regulatory protein interface [polypeptide binding]; other site
344609011239	active site
344609011240	regulatory phosphorylation site [posttranslational modification]; other site
344609011241	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
344609011242	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
344609011243	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
344609011244	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
344609011245	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
344609011246	active site
344609011247	phosphorylation site [posttranslational modification]
344609011248	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
344609011249	active site
344609011250	P-loop; other site
344609011251	phosphorylation site [posttranslational modification]
344609011252	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
344609011253	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
344609011254	dimer interface [polypeptide binding]; other site
344609011255	active site
344609011256	glycine loop; other site
344609011257	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
344609011258	FeS/SAM binding site; other site
344609011259	pyruvate formate lyase II activase; Provisional; Region: PRK10076
344609011260	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
344609011261	active site
344609011262	P-loop; other site
344609011263	phosphorylation site [posttranslational modification]
344609011264	hypothetical protein; Provisional; Region: PRK10649
344609011265	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
344609011266	Sulfatase; Region: Sulfatase; pfam00884
344609011267	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
344609011268	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
344609011269	acetylornithine deacetylase; Provisional; Region: PRK05111
344609011270	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
344609011271	metal binding site [ion binding]; metal-binding site
344609011272	putative dimer interface [polypeptide binding]; other site
344609011273	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
344609011274	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
344609011275	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
344609011276	nucleotide binding site [chemical binding]; other site
344609011277	N-acetyl-L-glutamate binding site [chemical binding]; other site
344609011278	argininosuccinate lyase; Provisional; Region: PRK04833
344609011279	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
344609011280	active sites [active]
344609011281	tetramer interface [polypeptide binding]; other site
344609011282	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
344609011283	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609011284	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
344609011285	dimerization interface [polypeptide binding]; other site
344609011286	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
344609011287	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
344609011288	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
344609011289	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
344609011290	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
344609011291	hypothetical protein; Provisional; Region: PRK11056
344609011292	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
344609011293	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609011294	S-adenosylmethionine binding site [chemical binding]; other site
344609011295	glutamate racemase; Provisional; Region: PRK00865
344609011296	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
344609011297	FAD binding domain; Region: FAD_binding_4; pfam01565
344609011298	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
344609011299	Biotin operon repressor [Transcription]; Region: BirA; COG1654
344609011300	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
344609011301	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
344609011302	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
344609011303	pantothenate kinase; Provisional; Region: PRK05439
344609011304	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
344609011305	ATP-binding site [chemical binding]; other site
344609011306	CoA-binding site [chemical binding]; other site
344609011307	Mg2+-binding site [ion binding]; other site
344609011308	elongation factor Tu; Reviewed; Region: PRK00049
344609011309	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
344609011310	G1 box; other site
344609011311	GEF interaction site [polypeptide binding]; other site
344609011312	GTP/Mg2+ binding site [chemical binding]; other site
344609011313	Switch I region; other site
344609011314	G2 box; other site
344609011315	G3 box; other site
344609011316	Switch II region; other site
344609011317	G4 box; other site
344609011318	G5 box; other site
344609011319	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
344609011320	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
344609011321	Antibiotic Binding Site [chemical binding]; other site
344609011322	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
344609011323	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
344609011324	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
344609011325	putative homodimer interface [polypeptide binding]; other site
344609011326	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
344609011327	heterodimer interface [polypeptide binding]; other site
344609011328	homodimer interface [polypeptide binding]; other site
344609011329	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
344609011330	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
344609011331	23S rRNA interface [nucleotide binding]; other site
344609011332	L7/L12 interface [polypeptide binding]; other site
344609011333	putative thiostrepton binding site; other site
344609011334	L25 interface [polypeptide binding]; other site
344609011335	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
344609011336	mRNA/rRNA interface [nucleotide binding]; other site
344609011337	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
344609011338	23S rRNA interface [nucleotide binding]; other site
344609011339	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
344609011340	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
344609011341	core dimer interface [polypeptide binding]; other site
344609011342	peripheral dimer interface [polypeptide binding]; other site
344609011343	L10 interface [polypeptide binding]; other site
344609011344	L11 interface [polypeptide binding]; other site
344609011345	putative EF-Tu interaction site [polypeptide binding]; other site
344609011346	putative EF-G interaction site [polypeptide binding]; other site
344609011347	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
344609011348	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
344609011349	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
344609011350	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
344609011351	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
344609011352	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
344609011353	RPB3 interaction site [polypeptide binding]; other site
344609011354	RPB1 interaction site [polypeptide binding]; other site
344609011355	RPB11 interaction site [polypeptide binding]; other site
344609011356	RPB10 interaction site [polypeptide binding]; other site
344609011357	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
344609011358	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
344609011359	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
344609011360	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
344609011361	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
344609011362	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
344609011363	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
344609011364	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
344609011365	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
344609011366	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
344609011367	DNA binding site [nucleotide binding]
344609011368	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
344609011369	stationary phase growth adaptation protein; Provisional; Region: PRK09717
344609011370	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011371	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
344609011372	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
344609011373	FeS/SAM binding site; other site
344609011374	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
344609011375	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
344609011376	ThiS interaction site; other site
344609011377	putative active site [active]
344609011378	tetramer interface [polypeptide binding]; other site
344609011379	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
344609011380	thiS-thiF/thiG interaction site; other site
344609011381	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
344609011382	thiamine phosphate binding site [chemical binding]; other site
344609011383	active site
344609011384	pyrophosphate binding site [ion binding]; other site
344609011385	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
344609011386	ThiC-associated domain; Region: ThiC-associated; pfam13667
344609011387	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
344609011388	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
344609011389	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
344609011390	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
344609011391	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
344609011392	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
344609011393	putative NADH binding site [chemical binding]; other site
344609011394	putative active site [active]
344609011395	nudix motif; other site
344609011396	putative metal binding site [ion binding]; other site
344609011397	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
344609011398	substrate binding site [chemical binding]; other site
344609011399	active site
344609011400	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
344609011401	Active_site [active]
344609011402	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
344609011403	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
344609011404	IHF dimer interface [polypeptide binding]; other site
344609011405	IHF - DNA interface [nucleotide binding]; other site
344609011406	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
344609011407	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
344609011408	dimer interface [polypeptide binding]; other site
344609011409	sensor protein ZraS; Provisional; Region: PRK10364
344609011410	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609011411	dimer interface [polypeptide binding]; other site
344609011412	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609011413	ATP binding site [chemical binding]; other site
344609011414	Mg2+ binding site [ion binding]; other site
344609011415	G-X-G motif; other site
344609011416	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
344609011417	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609011418	active site
344609011419	phosphorylation site [posttranslational modification]
344609011420	intermolecular recognition site; other site
344609011421	dimerization interface [polypeptide binding]; other site
344609011422	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609011423	Walker A motif; other site
344609011424	ATP binding site [chemical binding]; other site
344609011425	Walker B motif; other site
344609011426	arginine finger; other site
344609011427	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
344609011428	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
344609011429	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
344609011430	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
344609011431	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
344609011432	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
344609011433	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
344609011434	purine monophosphate binding site [chemical binding]; other site
344609011435	dimer interface [polypeptide binding]; other site
344609011436	putative catalytic residues [active]
344609011437	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
344609011438	homoserine O-succinyltransferase; Provisional; Region: PRK05368
344609011439	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
344609011440	proposed active site lysine [active]
344609011441	conserved cys residue [active]
344609011442	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
344609011443	malate synthase A; Region: malate_syn_A; TIGR01344
344609011444	active site
344609011445	isocitrate lyase; Provisional; Region: PRK15063
344609011446	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
344609011447	tetramer interface [polypeptide binding]; other site
344609011448	active site
344609011449	Mg2+/Mn2+ binding site [ion binding]; other site
344609011450	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
344609011451	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
344609011452	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011453	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
344609011454	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
344609011455	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
344609011456	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
344609011457	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
344609011458	active site pocket [active]
344609011459	oxyanion hole [active]
344609011460	catalytic triad [active]
344609011461	active site nucleophile [active]
344609011462	PTS system, mannose/fructose/sorbose family, IID component; Region: EIID-AGA; TIGR00828
344609011463	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
344609011464	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
344609011465	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
344609011466	active pocket/dimerization site; other site
344609011467	active site
344609011468	phosphorylation site [posttranslational modification]
344609011469	sorbitol-6-phosphate 2-dehydrogenase; Provisional; Region: PRK06171
344609011470	classical (c) SDRs; Region: SDR_c; cd05233
344609011471	NAD(P) binding site [chemical binding]; other site
344609011472	active site
344609011473	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
344609011474	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
344609011475	putative DNA binding site [nucleotide binding]; other site
344609011476	putative Zn2+ binding site [ion binding]; other site
344609011477	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
344609011478	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
344609011479	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
344609011480	RNA binding surface [nucleotide binding]; other site
344609011481	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
344609011482	probable active site [active]
344609011483	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011484	aspartate kinase III; Validated; Region: PRK09084
344609011485	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
344609011486	nucleotide binding site [chemical binding]; other site
344609011487	substrate binding site [chemical binding]; other site
344609011488	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
344609011489	lysine allosteric regulatory site; other site
344609011490	dimer interface [polypeptide binding]; other site
344609011491	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
344609011492	dimer interface [polypeptide binding]; other site
344609011493	Lysine riboswitch
344609011494	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
344609011495	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
344609011496	active site
344609011497	dimer interface [polypeptide binding]; other site
344609011498	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
344609011499	dimer interface [polypeptide binding]; other site
344609011500	active site
344609011501	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
344609011502	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
344609011503	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
344609011504	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
344609011505	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609011506	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011507	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
344609011508	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
344609011509	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609011510	homodimer interface [polypeptide binding]; other site
344609011511	catalytic residue [active]
344609011512	alanine racemase; Reviewed; Region: alr; PRK00053
344609011513	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
344609011514	active site
344609011515	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
344609011516	substrate binding site [chemical binding]; other site
344609011517	catalytic residues [active]
344609011518	dimer interface [polypeptide binding]; other site
344609011519	replicative DNA helicase; Provisional; Region: PRK08006
344609011520	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
344609011521	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
344609011522	Walker A motif; other site
344609011523	ATP binding site [chemical binding]; other site
344609011524	Walker B motif; other site
344609011525	DNA binding loops [nucleotide binding]
344609011526	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
344609011527	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
344609011528	NADP binding site [chemical binding]; other site
344609011529	dimer interface [polypeptide binding]; other site
344609011530	phage shock protein G; Reviewed; Region: pspG; PRK09459
344609011531	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
344609011532	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
344609011533	FMN binding site [chemical binding]; other site
344609011534	active site
344609011535	catalytic residues [active]
344609011536	substrate binding site [chemical binding]; other site
344609011537	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011538	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
344609011539	metal binding site 2 [ion binding]; metal-binding site
344609011540	putative DNA binding helix; other site
344609011541	metal binding site 1 [ion binding]; metal-binding site
344609011542	dimer interface [polypeptide binding]; other site
344609011543	structural Zn2+ binding site [ion binding]; other site
344609011544	hypothetical protein; Provisional; Region: PRK10428
344609011545	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
344609011546	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
344609011547	LexA repressor; Validated; Region: PRK00215
344609011548	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
344609011549	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
344609011550	Catalytic site [active]
344609011551	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
344609011552	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
344609011553	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
344609011554	putative acyl-acceptor binding pocket; other site
344609011555	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
344609011556	UbiA prenyltransferase family; Region: UbiA; pfam01040
344609011557	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
344609011558	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609011559	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609011560	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609011561	SopA-like central domain; Region: SopA; pfam13981
344609011562	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011563	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
344609011564	SopA-like central domain; Region: SopA; pfam13981
344609011565	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011566	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609011567	active site
344609011568	motif I; other site
344609011569	motif II; other site
344609011570	Uncharacterized protein family UPF0047; Region: UPF0047; cl00439
344609011571	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
344609011572	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
344609011573	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
344609011574	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
344609011575	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
344609011576	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
344609011577	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
344609011578	dimer interface [polypeptide binding]; other site
344609011579	ssDNA binding site [nucleotide binding]; other site
344609011580	tetramer (dimer of dimers) interface [polypeptide binding]; other site
344609011581	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
344609011582	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
344609011583	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
344609011584	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609011585	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
344609011586	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
344609011587	DNA binding residues [nucleotide binding]
344609011588	dimer interface [polypeptide binding]; other site
344609011589	[2Fe-2S] cluster binding site [ion binding]; other site
344609011590	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
344609011591	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
344609011592	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
344609011593	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011594	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
344609011595	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
344609011596	Na binding site [ion binding]; other site
344609011597	Predicted membrane protein [Function unknown]; Region: COG3162
344609011598	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
344609011599	CoA binding site [chemical binding]; other site
344609011600	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609011601	HTH-like domain; Region: HTH_21; pfam13276
344609011602	Integrase core domain; Region: rve; pfam00665
344609011603	Integrase core domain; Region: rve_3; pfam13683
344609011604	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
344609011605	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
344609011606	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
344609011607	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
344609011608	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
344609011609	heme lyase subunit NrfE; Provisional; Region: PRK10369
344609011610	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
344609011611	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
344609011612	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
344609011613	binding surface
344609011614	TPR motif; other site
344609011615	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
344609011616	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
344609011617	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011618	Bacterial phosphonate metabolism protein (PhnH); Region: PhnH; cl01455
344609011619	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnG; COG3624
344609011620	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
344609011621	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
344609011622	dimer interface [polypeptide binding]; other site
344609011623	conserved gate region; other site
344609011624	putative PBP binding loops; other site
344609011625	ABC-ATPase subunit interface; other site
344609011626	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
344609011627	Tripartite tricarboxylate transporter family receptor; Region: TctC; cl17792
344609011628	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
344609011629	dimer interface [polypeptide binding]; other site
344609011630	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
344609011631	hypothetical protein; Provisional; Region: PRK10220
344609011632	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
344609011633	PhnA protein; Region: PhnA; pfam03831
344609011634	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011635	arginine:agmatin antiporter; Provisional; Region: PRK10644
344609011636	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
344609011637	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609011638	arginine decarboxylase; Provisional; Region: PRK15029
344609011639	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
344609011640	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
344609011641	homodimer interface [polypeptide binding]; other site
344609011642	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609011643	catalytic residue [active]
344609011644	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
344609011645	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
344609011646	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609011647	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609011648	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609011649	Transposase; Region: HTH_Tnp_1; pfam01527
344609011650	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
344609011651	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011652	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609011653	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609011654	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609011655	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609011656	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609011657	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609011658	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609011659	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609011660	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609011661	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609011662	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609011663	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609011664	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609011665	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609011666	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609011667	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609011668	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
344609011669	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
344609011670	N-terminal plug; other site
344609011671	ligand-binding site [chemical binding]; other site
344609011672	Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: IucD; COG3486
344609011673	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
344609011674	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
344609011675	IucA / IucC family; Region: IucA_IucC; pfam04183
344609011676	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
344609011677	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
344609011678	Siderophore biosynthesis protein domain; Region: AlcB; smart01006
344609011679	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
344609011680	IucA / IucC family; Region: IucA_IucC; pfam04183
344609011681	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
344609011682	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609011683	Major Facilitator Superfamily; Region: MFS_1; pfam07690
344609011684	putative substrate translocation pore; other site
344609011685	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609011686	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609011687	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609011688	Transposase; Region: HTH_Tnp_1; pfam01527
344609011689	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
344609011690	dimer interface [polypeptide binding]; other site
344609011691	motif 1; other site
344609011692	motif 2; other site
344609011693	putative transposase OrfB; Reviewed; Region: PHA02517
344609011694	HTH-like domain; Region: HTH_21; pfam13276
344609011695	Integrase core domain; Region: rve; pfam00665
344609011696	Integrase core domain; Region: rve_3; pfam13683
344609011697	Transposase; Region: HTH_Tnp_1; cl17663
344609011698	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609011699	Transposase; Region: HTH_Tnp_1; pfam01527
344609011700	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609011701	HTH-like domain; Region: HTH_21; pfam13276
344609011702	Integrase core domain; Region: rve; pfam00665
344609011703	Integrase core domain; Region: rve_3; pfam13683
344609011704	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011705	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
344609011706	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
344609011707	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
344609011708	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
344609011709	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
344609011710	Autotransporter beta-domain; Region: Autotransporter; pfam03797
344609011711	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609011712	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609011713	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609011714	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609011715	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609011716	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609011717	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609011718	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609011719	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609011720	putative transposase OrfB; Reviewed; Region: PHA02517
344609011721	Integrase core domain; Region: rve; pfam00665
344609011722	Integrase core domain; Region: rve_3; pfam13683
344609011723	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609011724	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609011725	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609011726	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609011727	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609011728	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609011729	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609011730	Integrase core domain; Region: rve; pfam00665
344609011731	Integrase core domain; Region: rve_3; pfam13683
344609011732	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
344609011733	putative transcriptional regulator; Provisional; Region: PRK11640
344609011734	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
344609011735	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
344609011736	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
344609011737	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
344609011738	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
344609011739	DsbD alpha interface [polypeptide binding]; other site
344609011740	catalytic residues [active]
344609011741	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
344609011742	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
344609011743	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
344609011744	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
344609011745	Aspartase; Region: Aspartase; cd01357
344609011746	active sites [active]
344609011747	tetramer interface [polypeptide binding]; other site
344609011748	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
344609011749	putative transporter; Provisional; Region: PRK11021
344609011750	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
344609011751	oligomerisation interface [polypeptide binding]; other site
344609011752	mobile loop; other site
344609011753	roof hairpin; other site
344609011754	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
344609011755	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
344609011756	ring oligomerisation interface [polypeptide binding]; other site
344609011757	ATP/Mg binding site [chemical binding]; other site
344609011758	stacking interactions; other site
344609011759	hinge regions; other site
344609011760	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
344609011761	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
344609011762	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
344609011763	FeS/SAM binding site; other site
344609011764	elongation factor P; Validated; Region: PRK00529
344609011765	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
344609011766	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
344609011767	RNA binding site [nucleotide binding]; other site
344609011768	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
344609011769	RNA binding site [nucleotide binding]; other site
344609011770	entericidin A; Provisional; Region: PRK09810
344609011771	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
344609011772	multidrug efflux system protein; Provisional; Region: PRK11431
344609011773	Bacterial lipocalin [Cell envelope biogenesis, outer membrane]; Region: Blc; COG3040
344609011774	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
344609011775	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
344609011776	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
344609011777	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
344609011778	Iron-sulfur protein interface; other site
344609011779	proximal quinone binding site [chemical binding]; other site
344609011780	C-subunit interface; other site
344609011781	distal quinone binding site; other site
344609011782	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
344609011783	D-subunit interface [polypeptide binding]; other site
344609011784	Iron-sulfur protein interface; other site
344609011785	proximal quinone binding site [chemical binding]; other site
344609011786	distal quinone binding site [chemical binding]; other site
344609011787	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
344609011788	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
344609011789	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
344609011790	L-aspartate oxidase; Provisional; Region: PRK06175
344609011791	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
344609011792	poxB regulator PoxA; Provisional; Region: PRK09350
344609011793	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
344609011794	motif 1; other site
344609011795	dimer interface [polypeptide binding]; other site
344609011796	active site
344609011797	motif 2; other site
344609011798	motif 3; other site
344609011799	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011800	inner membrane transporter YjeM; Provisional; Region: PRK15238
344609011801	putative mechanosensitive channel protein; Provisional; Region: PRK10929
344609011802	linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated...; Region: H15; cl00073
344609011803	DNA-binding site [nucleotide binding]; DNA binding site
344609011804	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
344609011805	Mechanosensitive ion channel; Region: MS_channel; pfam00924
344609011806	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
344609011807	GTPase RsgA; Reviewed; Region: PRK12288
344609011808	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
344609011809	RNA binding site [nucleotide binding]; other site
344609011810	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
344609011811	GTPase/Zn-binding domain interface [polypeptide binding]; other site
344609011812	GTP/Mg2+ binding site [chemical binding]; other site
344609011813	G4 box; other site
344609011814	G5 box; other site
344609011815	G1 box; other site
344609011816	Switch I region; other site
344609011817	G2 box; other site
344609011818	G3 box; other site
344609011819	Switch II region; other site
344609011820	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
344609011821	catalytic site [active]
344609011822	putative active site [active]
344609011823	putative substrate binding site [chemical binding]; other site
344609011824	dimer interface [polypeptide binding]; other site
344609011825	epoxyqueuosine reductase; Region: TIGR00276
344609011826	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
344609011827	putative carbohydrate kinase; Provisional; Region: PRK10565
344609011828	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
344609011829	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
344609011830	putative substrate binding site [chemical binding]; other site
344609011831	putative ATP binding site [chemical binding]; other site
344609011832	ADP-binding protein; Provisional; Region: PRK10646
344609011833	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
344609011834	AMIN domain; Region: AMIN; pfam11741
344609011835	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
344609011836	active site
344609011837	metal binding site [ion binding]; metal-binding site
344609011838	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
344609011839	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609011840	ATP binding site [chemical binding]; other site
344609011841	Mg2+ binding site [ion binding]; other site
344609011842	G-X-G motif; other site
344609011843	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
344609011844	ATP binding site [chemical binding]; other site
344609011845	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
344609011846	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
344609011847	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
344609011848	bacterial Hfq-like; Region: Hfq; cd01716
344609011849	hexamer interface [polypeptide binding]; other site
344609011850	Sm1 motif; other site
344609011851	RNA binding site [nucleotide binding]; other site
344609011852	Sm2 motif; other site
344609011853	GTPase HflX; Provisional; Region: PRK11058
344609011854	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
344609011855	HflX GTPase family; Region: HflX; cd01878
344609011856	G1 box; other site
344609011857	GTP/Mg2+ binding site [chemical binding]; other site
344609011858	Switch I region; other site
344609011859	G2 box; other site
344609011860	G3 box; other site
344609011861	Switch II region; other site
344609011862	G4 box; other site
344609011863	G5 box; other site
344609011864	FtsH protease regulator HflK; Provisional; Region: PRK10930
344609011865	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
344609011866	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
344609011867	FtsH protease regulator HflC; Provisional; Region: PRK11029
344609011868	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
344609011869	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
344609011870	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
344609011871	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
344609011872	GDP-binding site [chemical binding]; other site
344609011873	ACT binding site; other site
344609011874	IMP binding site; other site
344609011875	Predicted transcriptional regulator [Transcription]; Region: COG1959
344609011876	transcriptional repressor NsrR; Provisional; Region: PRK11014
344609011877	exoribonuclease R; Provisional; Region: PRK11642
344609011878	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
344609011879	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
344609011880	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
344609011881	RNB domain; Region: RNB; pfam00773
344609011882	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
344609011883	RNA binding site [nucleotide binding]; other site
344609011884	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
344609011885	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
344609011886	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
344609011887	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011888	Predicted membrane protein [Function unknown]; Region: COG3766
344609011889	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
344609011890	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
344609011891	Predicted integral membrane protein [Function unknown]; Region: COG5463
344609011892	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
344609011893	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
344609011894	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
344609011895	FAD binding site [chemical binding]; other site
344609011896	substrate binding site [chemical binding]; other site
344609011897	catalytic residues [active]
344609011898	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
344609011899	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
344609011900	esterase; Provisional; Region: PRK10566
344609011901	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
344609011902	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
344609011903	transcriptional repressor UlaR; Provisional; Region: PRK13509
344609011904	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
344609011905	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
344609011906	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
344609011907	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
344609011908	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
344609011909	active site
344609011910	P-loop; other site
344609011911	phosphorylation site [posttranslational modification]
344609011912	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
344609011913	active site
344609011914	phosphorylation site [posttranslational modification]
344609011915	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
344609011916	active site
344609011917	dimer interface [polypeptide binding]; other site
344609011918	magnesium binding site [ion binding]; other site
344609011919	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
344609011920	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
344609011921	AP (apurinic/apyrimidinic) site pocket; other site
344609011922	DNA interaction; other site
344609011923	Metal-binding active site; metal-binding site
344609011924	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
344609011925	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
344609011926	intersubunit interface [polypeptide binding]; other site
344609011927	active site
344609011928	Zn2+ binding site [ion binding]; other site
344609011929	Protein of unknown function (DUF1440); Region: DUF1440; pfam07274
344609011930	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
344609011931	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
344609011932	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
344609011933	dimer interface [polypeptide binding]; other site
344609011934	ssDNA binding site [nucleotide binding]; other site
344609011935	tetramer (dimer of dimers) interface [polypeptide binding]; other site
344609011936	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
344609011937	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
344609011938	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
344609011939	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
344609011940	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
344609011941	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Region: SdhA; COG1053
344609011942	L-aspartate oxidase; Provisional; Region: PRK06175
344609011943	L-aspartate oxidase; Provisional; Region: PRK06175
344609011944	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
344609011945	Coenzyme A transferase; Region: CoA_trans; smart00882
344609011946	Coenzyme A transferase; Region: CoA_trans; cl17247
344609011947	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
344609011948	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
344609011949	substrate binding site [chemical binding]; other site
344609011950	oxyanion hole (OAH) forming residues; other site
344609011951	trimer interface [polypeptide binding]; other site
344609011952	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: PRK12745
344609011953	putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR), subgroup 1, classical (c) SDR; Region: BKR_1_SDR_c; cd05337
344609011954	putative NAD(P) binding site [chemical binding]; other site
344609011955	active site
344609011956	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
344609011957	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
344609011958	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
344609011959	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
344609011960	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
344609011961	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
344609011962	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
344609011963	Hemerythrin-like domain; Region: Hr-like; cd12108
344609011964	Fe binding site [ion binding]; other site
344609011965	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
344609011966	EamA-like transporter family; Region: EamA; pfam00892
344609011967	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
344609011968	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
344609011969	NADP binding site [chemical binding]; other site
344609011970	Predicted transcriptional regulators [Transcription]; Region: COG1733
344609011971	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
344609011972	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
344609011973	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609011974	Transposase; Region: HTH_Tnp_1; pfam01527
344609011975	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
344609011976	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
344609011977	active site
344609011978	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609011979	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609011980	HTH-like domain; Region: HTH_21; pfam13276
344609011981	Integrase core domain; Region: rve; pfam00665
344609011982	Integrase core domain; Region: rve_3; pfam13683
344609011983	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
344609011984	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
344609011985	DNA-binding site [nucleotide binding]; DNA binding site
344609011986	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
344609011987	pyridoxal 5'-phosphate binding site [chemical binding]; other site
344609011988	homodimer interface [polypeptide binding]; other site
344609011989	catalytic residue [active]
344609011990	putative transposase OrfB; Reviewed; Region: PHA02517
344609011991	HTH-like domain; Region: HTH_21; pfam13276
344609011992	Integrase core domain; Region: rve; pfam00665
344609011993	Integrase core domain; Region: rve_3; pfam13683
344609011994	Transposase; Region: HTH_Tnp_1; cl17663
344609011995	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609011996	Transposase; Region: HTH_Tnp_1; pfam01527
344609011997	Uncharacterized conserved protein [Function unknown]; Region: COG5464
344609011998	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
344609011999	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
344609012000	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609012001	putative substrate translocation pore; other site
344609012002	Predicted membrane protein [Function unknown]; Region: COG2733
344609012003	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
344609012004	CoA-substrate-specific enzyme activase, putative; Region: CoA_E_activ; TIGR00241
344609012005	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
344609012006	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
344609012007	SdiA-regulated; Region: SdiA-regulated; cd09971
344609012008	putative active site [active]
344609012009	Major Facilitator Superfamily; Region: MFS_1; pfam07690
344609012010	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
344609012011	putative substrate translocation pore; other site
344609012012	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
344609012013	RNA 2'-phosphotransferase; Reviewed; Region: PRK00819
344609012014	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
344609012015	Nucleoside recognition; Region: Gate; pfam07670
344609012016	Isoaspartyl dipeptidase hydrolyzes the beta-L-isoaspartyl linkages in dipeptides, as part of the degradative pathway to eliminate proteins with beta-L-isoaspartyl peptide bonds, bonds whereby the beta-group of an aspartate forms the peptide link with the...; Region: Isoaspartyl-dipeptidase; cd01308
344609012017	isoaspartyl dipeptidase IadA; Region: isoAsp_dipep; TIGR01975
344609012018	dimer interface [polypeptide binding]; other site
344609012019	active site
344609012020	cell density-dependent motility repressor; Provisional; Region: PRK10082
344609012021	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
344609012022	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
344609012023	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
344609012024	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609012025	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
344609012026	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609012027	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
344609012028	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
344609012029	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
344609012030	DNA-binding site [nucleotide binding]; DNA binding site
344609012031	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
344609012032	D-mannonate oxidoreductase; Provisional; Region: PRK15037
344609012033	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
344609012034	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
344609012035	mannonate dehydratase; Region: uxuA; TIGR00695
344609012036	mannonate dehydratase; Provisional; Region: PRK03906
344609012037	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
344609012038	mannosyl binding site [chemical binding]; other site
344609012039	Fimbrial protein; Region: Fimbrial; pfam00419
344609012040	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
344609012041	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609012042	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
344609012043	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
344609012044	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609012045	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
344609012046	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
344609012047	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
344609012048	ATP binding site [chemical binding]; other site
344609012049	putative Mg++ binding site [ion binding]; other site
344609012050	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
344609012051	HsdM N-terminal domain; Region: HsdM_N; pfam12161
344609012052	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
344609012053	Methyltransferase domain; Region: Methyltransf_26; pfam13659
344609012054	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
344609012055	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
344609012056	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
344609012057	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609012058	integrase; Provisional; Region: PRK09692
344609012059	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
344609012060	active site
344609012061	Int/Topo IB signature motif; other site
344609012062	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
344609012063	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
344609012064	putative NAD(P) binding site [chemical binding]; other site
344609012065	putative substrate binding site [chemical binding]; other site
344609012066	catalytic Zn binding site [ion binding]; other site
344609012067	structural Zn binding site [ion binding]; other site
344609012068	dimer interface [polypeptide binding]; other site
344609012069	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
344609012070	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
344609012071	Walker A motif; other site
344609012072	ATP binding site [chemical binding]; other site
344609012073	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
344609012074	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
344609012075	multifunctional aminopeptidase A; Provisional; Region: PRK00913
344609012076	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
344609012077	interface (dimer of trimers) [polypeptide binding]; other site
344609012078	Substrate-binding/catalytic site; other site
344609012079	Zn-binding sites [ion binding]; other site
344609012080	DNA polymerase III subunit chi; Validated; Region: PRK05728
344609012081	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
344609012082	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
344609012083	HIGH motif; other site
344609012084	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
344609012085	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
344609012086	active site
344609012087	KMSKS motif; other site
344609012088	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
344609012089	tRNA binding surface [nucleotide binding]; other site
344609012090	anticodon binding site; other site
344609012091	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
344609012092	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609012093	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
344609012094	RNase E inhibitor protein; Provisional; Region: PRK11191
344609012095	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
344609012096	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
344609012097	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
344609012098	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609012099	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
344609012100	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
344609012101	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
344609012102	oxidoreductase; Provisional; Region: PRK12742
344609012103	classical (c) SDRs; Region: SDR_c; cd05233
344609012104	NAD(P) binding site [chemical binding]; other site
344609012105	active site
344609012106	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
344609012107	homotrimer interaction site [polypeptide binding]; other site
344609012108	putative active site [active]
344609012109	PyrBI operon leader peptide; Region: PyrBI_leader; pfam08052
344609012110	aspartate carbamoyltransferase; Region: asp_carb_tr; TIGR00670
344609012111	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
344609012112	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
344609012113	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
344609012114	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
344609012115	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
344609012116	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
344609012117	homotrimer interaction site [polypeptide binding]; other site
344609012118	putative active site [active]
344609012119	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
344609012120	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
344609012121	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
344609012122	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
344609012123	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609012124	motif II; other site
344609012125	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
344609012126	trehalose repressor; Provisional; Region: treR; PRK09492
344609012127	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
344609012128	DNA binding site [nucleotide binding]
344609012129	domain linker motif; other site
344609012130	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
344609012131	dimerization interface [polypeptide binding]; other site
344609012132	ligand binding site [chemical binding]; other site
344609012133	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
344609012134	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
344609012135	active site turn [active]
344609012136	phosphorylation site [posttranslational modification]
344609012137	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
344609012138	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
344609012139	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
344609012140	Ca binding site [ion binding]; other site
344609012141	active site
344609012142	catalytic site [active]
344609012143	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
344609012144	ATP cone domain; Region: ATP-cone; pfam03477
344609012145	Class III ribonucleotide reductase; Region: RNR_III; cd01675
344609012146	effector binding site; other site
344609012147	active site
344609012148	Zn binding site [ion binding]; other site
344609012149	glycine loop; other site
344609012150	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
344609012151	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
344609012152	FeS/SAM binding site; other site
344609012153	cytochrome b562; Provisional; Region: PRK15058
344609012154	peptidase PmbA; Provisional; Region: PRK11040
344609012155	hypothetical protein; Provisional; Region: PRK05255
344609012156	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
344609012157	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
344609012158	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
344609012159	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
344609012160	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
344609012161	AMP binding site [chemical binding]; other site
344609012162	metal binding site [ion binding]; metal-binding site
344609012163	active site
344609012164	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
344609012165	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
344609012166	TM-ABC transporter signature motif; other site
344609012167	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
344609012168	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
344609012169	TM-ABC transporter signature motif; other site
344609012170	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
344609012171	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
344609012172	putative ligand binding site [chemical binding]; other site
344609012173	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
344609012174	dimer interface [polypeptide binding]; other site
344609012175	substrate binding site [chemical binding]; other site
344609012176	metal binding sites [ion binding]; metal-binding site
344609012177	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
344609012178	putative active site pocket [active]
344609012179	dimerization interface [polypeptide binding]; other site
344609012180	putative catalytic residue [active]
344609012181	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
344609012182	Family of unknown function (DUF490); Region: DUF490; pfam04357
344609012183	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
344609012184	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
344609012185	Surface antigen; Region: Bac_surface_Ag; pfam01103
344609012186	methionine sulfoxide reductase A; Provisional; Region: PRK00058
344609012187	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
344609012188	Domain of unknown function DUF21; Region: DUF21; pfam01595
344609012189	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
344609012190	Transporter associated domain; Region: CorC_HlyC; smart01091
344609012191	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
344609012192	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
344609012193	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609012194	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609012195	HTH-like domain; Region: HTH_21; pfam13276
344609012196	Integrase core domain; Region: rve; pfam00665
344609012197	Integrase core domain; Region: rve_3; pfam13683
344609012198	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609012199	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609012200	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609012201	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
344609012202	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
344609012203	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
344609012204	P-loop, Walker A motif; other site
344609012205	Base recognition motif; other site
344609012206	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
344609012207	Uncharacterized small protein [Function unknown]; Region: COG2879
344609012208	carbon starvation protein A; Provisional; Region: PRK15015
344609012209	Carbon starvation protein CstA; Region: CstA; pfam02554
344609012210	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
344609012211	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
344609012212	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
344609012213	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
344609012214	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
344609012215	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
344609012216	putative substrate binding pocket [chemical binding]; other site
344609012217	trimer interface [polypeptide binding]; other site
344609012218	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
344609012219	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
344609012220	putative active site [active]
344609012221	putative metal binding site [ion binding]; other site
344609012222	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
344609012223	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
344609012224	NAD binding site [chemical binding]; other site
344609012225	catalytic residues [active]
344609012226	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
344609012227	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit; Region: HpaG-N-term; TIGR02305
344609012228	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
344609012229	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
344609012230	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
344609012231	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
344609012232	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
344609012233	dimer interface [polypeptide binding]; other site
344609012234	ligand binding site [chemical binding]; other site
344609012235	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
344609012236	dimerization interface [polypeptide binding]; other site
344609012237	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
344609012238	dimer interface [polypeptide binding]; other site
344609012239	putative CheW interface [polypeptide binding]; other site
344609012240	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609012241	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
344609012242	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
344609012243	putative NAD(P) binding site [chemical binding]; other site
344609012244	catalytic Zn binding site [ion binding]; other site
344609012245	structural Zn binding site [ion binding]; other site
344609012246	phosphoglycerol transferase I; Provisional; Region: PRK03776
344609012247	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
344609012248	hypothetical protein; Provisional; Region: PRK11667
344609012249	DNA replication protein DnaC; Validated; Region: PRK07952
344609012250	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609012251	Walker A motif; other site
344609012252	ATP binding site [chemical binding]; other site
344609012253	Walker B motif; other site
344609012254	primosomal protein DnaI; Provisional; Region: PRK02854
344609012255	hypothetical protein; Provisional; Region: PRK09917
344609012256	Uncharacterized conserved protein [Function unknown]; Region: COG2966
344609012257	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
344609012258	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609012259	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
344609012260	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
344609012261	DNA binding residues [nucleotide binding]
344609012262	dimerization interface [polypeptide binding]; other site
344609012263	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
344609012264	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
344609012265	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
344609012266	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
344609012267	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
344609012268	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
344609012269	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
344609012270	S-adenosylmethionine binding site [chemical binding]; other site
344609012271	DNA polymerase III subunit psi; Validated; Region: PRK06856
344609012272	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
344609012273	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
344609012274	Coenzyme A binding pocket [chemical binding]; other site
344609012275	dUMP phosphatase; Provisional; Region: PRK09449
344609012276	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609012277	motif II; other site
344609012278	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
344609012279	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
344609012280	G1 box; other site
344609012281	putative GEF interaction site [polypeptide binding]; other site
344609012282	GTP/Mg2+ binding site [chemical binding]; other site
344609012283	Switch I region; other site
344609012284	G2 box; other site
344609012285	G3 box; other site
344609012286	Switch II region; other site
344609012287	G4 box; other site
344609012288	G5 box; other site
344609012289	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
344609012290	periplasmic protein; Provisional; Region: PRK10568
344609012291	BON domain; Region: BON; pfam04972
344609012292	BON domain; Region: BON; pfam04972
344609012293	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
344609012294	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
344609012295	active site
344609012296	nucleophile elbow; other site
344609012297	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
344609012298	active site
344609012299	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
344609012300	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
344609012301	FeS/SAM binding site; other site
344609012302	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012303	Transposase; Region: HTH_Tnp_1; pfam01527
344609012304	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
344609012305	intersubunit interface [polypeptide binding]; other site
344609012306	active site
344609012307	catalytic residue [active]
344609012308	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
344609012309	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
344609012310	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
344609012311	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
344609012312	phosphopentomutase; Provisional; Region: PRK05362
344609012313	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
344609012314	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
344609012315	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
344609012316	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
344609012317	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
344609012318	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
344609012319	hypothetical protein; Provisional; Region: PRK11246
344609012320	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
344609012321	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
344609012322	motif II; other site
344609012323	DNA repair protein RadA; Region: sms; TIGR00416
344609012324	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
344609012325	Walker A motif/ATP binding site; other site
344609012326	ATP binding site [chemical binding]; other site
344609012327	Walker B motif; other site
344609012328	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
344609012329	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
344609012330	non-specific DNA binding site [nucleotide binding]; other site
344609012331	salt bridge; other site
344609012332	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
344609012333	sequence-specific DNA binding site [nucleotide binding]; other site
344609012334	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
344609012335	active site
344609012336	(T/H)XGH motif; other site
344609012337	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
344609012338	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
344609012339	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
344609012340	Walker A/P-loop; other site
344609012341	ATP binding site [chemical binding]; other site
344609012342	Q-loop/lid; other site
344609012343	ABC transporter signature motif; other site
344609012344	Walker B; other site
344609012345	D-loop; other site
344609012346	H-loop/switch region; other site
344609012347	ABC transporter; Region: ABC_tran_2; pfam12848
344609012348	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
344609012349	lytic murein transglycosylase; Provisional; Region: PRK11619
344609012350	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
344609012351	N-acetyl-D-glucosamine binding site [chemical binding]; other site
344609012352	catalytic residue [active]
344609012353	Trp operon repressor; Provisional; Region: PRK01381
344609012354	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
344609012355	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
344609012356	catalytic core [active]
344609012357	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
344609012358	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609012359	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
344609012360	hypothetical protein; Provisional; Region: PRK10756
344609012361	CreA protein; Region: CreA; pfam05981
344609012362	DNA-binding response regulator CreB; Provisional; Region: PRK11083
344609012363	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609012364	active site
344609012365	phosphorylation site [posttranslational modification]
344609012366	intermolecular recognition site; other site
344609012367	dimerization interface [polypeptide binding]; other site
344609012368	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
344609012369	DNA binding site [nucleotide binding]
344609012370	sensory histidine kinase CreC; Provisional; Region: PRK11100
344609012371	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
344609012372	dimerization interface [polypeptide binding]; other site
344609012373	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
344609012374	dimer interface [polypeptide binding]; other site
344609012375	phosphorylation site [posttranslational modification]
344609012376	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
344609012377	ATP binding site [chemical binding]; other site
344609012378	Mg2+ binding site [ion binding]; other site
344609012379	G-X-G motif; other site
344609012380	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
344609012381	two-component response regulator; Provisional; Region: PRK11173
344609012382	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
344609012383	active site
344609012384	phosphorylation site [posttranslational modification]
344609012385	intermolecular recognition site; other site
344609012386	dimerization interface [polypeptide binding]; other site
344609012387	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
344609012388	DNA binding site [nucleotide binding]
344609012389	putative RNA methyltransferase; Provisional; Region: PRK10433
344609012390	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050
344609012391	Replicase family; Region: Replicase; pfam03090
344609012392	Primase C terminal 1 (PriCT-1); Region: PriCT_1; pfam08708
344609012393	Homeodomain-like domain; Region: HTH_23; pfam13384
344609012394	Conjugal transfer protein TraD; Region: TraD; pfam06412
344609012395	MobA/MobL family; Region: MobA_MobL; pfam03389
344609012396	Ubiquitin-like proteins; Region: UBQ; cl00155
344609012397	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609012398	HTH-like domain; Region: HTH_21; pfam13276
344609012399	Integrase core domain; Region: rve; pfam00665
344609012400	Integrase core domain; Region: rve_3; pfam13683
344609012401	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
344609012402	active site
344609012403	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
344609012404	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609012405	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609012406	HTH-like domain; Region: HTH_21; pfam13276
344609012407	Integrase core domain; Region: rve; pfam00665
344609012408	Integrase core domain; Region: rve_3; pfam13683
344609012409	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609012410	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609012411	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609012412	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609012413	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609012414	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609012415	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609012416	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609012417	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609012418	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609012419	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609012420	Transposase; Region: HTH_Tnp_1; pfam01527
344609012421	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012422	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012423	Transposase; Region: HTH_Tnp_1; pfam01527
344609012424	AE_Prim_S_like: primase domain similar to that found in the small subunit of archaeal and eukaryotic (A/E) DNA primases. The replication machineries of A/Es are distinct from that of bacteria. Primases are DNA-dependent RNA polymerases which synthesis...; Region: AE_Prim_S_like; cl01287
344609012425	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
344609012426	Salmonella virulence-associated 28kDa protein; Region: VRP3; pfam03536
344609012427	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
344609012428	Transposase; Region: DDE_Tnp_ISL3; pfam01610
344609012429	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609012430	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609012431	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609012432	Transposase; Region: HTH_Tnp_1; pfam01527
344609012433	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012434	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609012435	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609012436	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609012437	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609012438	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609012439	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609012440	IpaB/EvcA family; Region: IpaB_EvcA; pfam03278
344609012441	Group II catalytic intron
344609012442	Integrase core domain; Region: rve; pfam00665
344609012443	Integrase core domain; Region: rve_2; pfam13333
344609012444	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
344609012445	Helix-turn-helix domain; Region: HTH_38; pfam13936
344609012446	Integrase core domain; Region: rve; pfam00665
344609012447	transposase/IS protein; Provisional; Region: PRK09183
344609012448	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
344609012449	Walker A motif; other site
344609012450	ATP binding site [chemical binding]; other site
344609012451	Walker B motif; other site
344609012452	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
344609012453	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
344609012454	Magnesium ion binding site [ion binding]; other site
344609012455	ParB-like nuclease domain; Region: ParB; smart00470
344609012456	ParB family; Region: ParB; pfam08775
344609012457	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
344609012458	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609012459	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609012460	Group II catalytic intron
344609012461	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
344609012462	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
344609012463	putative active site [active]
344609012464	putative NTP binding site [chemical binding]; other site
344609012465	putative nucleic acid binding site [nucleotide binding]; other site
344609012466	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
344609012467	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609012468	Transposase; Region: HTH_Tnp_1; cl17663
344609012469	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012470	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012471	Transposase; Region: HTH_Tnp_1; pfam01527
344609012472	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609012473	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609012474	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609012475	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609012476	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609012477	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
344609012478	Histone acetyltransferase HPA2 and related acetyltransferases [Transcription / General function prediction only]; Region: WecD; COG0454
344609012479	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
344609012480	Group II catalytic intron
344609012481	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012482	Transposase; Region: HTH_Tnp_1; pfam01527
344609012483	Transposase; Region: HTH_Tnp_1; pfam01527
344609012484	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012485	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609012486	HTH-like domain; Region: HTH_21; pfam13276
344609012487	Integrase core domain; Region: rve; pfam00665
344609012488	Integrase core domain; Region: rve_3; pfam13683
344609012489	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609012490	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609012491	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609012492	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609012493	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609012494	Transposase; Region: HTH_Tnp_1; cl17663
344609012495	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012496	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012497	Transposase; Region: HTH_Tnp_1; pfam01527
344609012498	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
344609012499	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
344609012500	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
344609012501	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012502	Transposase; Region: HTH_Tnp_1; pfam01527
344609012503	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
344609012504	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
344609012505	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
344609012506	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
344609012507	non-specific DNA binding site [nucleotide binding]; other site
344609012508	salt bridge; other site
344609012509	sequence-specific DNA binding site [nucleotide binding]; other site
344609012510	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
344609012511	Putative transposase; Region: Y2_Tnp; pfam04986
344609012512	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; cl14901
344609012513	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
344609012514	Putative transposase; Region: Y2_Tnp; pfam04986
344609012515	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
344609012516	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
344609012517	membrane-bound complex binding site; other site
344609012518	hinge residues; other site
344609012519	Shigella flexneri OspC protein; Region: Shigella_OspC; pfam06128
344609012520	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609012521	Group II catalytic intron
344609012522	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
344609012523	active site
344609012524	Uncharacterized conserved protein [Function unknown]; Region: COG3391
344609012525	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
344609012526	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
344609012527	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
344609012528	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
344609012529	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
344609012530	Protein of unknown function, DUF399; Region: DUF399; pfam04187
344609012531	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
344609012532	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
344609012533	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609012534	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609012535	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
344609012536	Homeodomain-like domain; Region: HTH_23; pfam13384
344609012537	Winged helix-turn helix; Region: HTH_29; pfam13551
344609012538	Homeodomain-like domain; Region: HTH_32; pfam13565
344609012539	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
344609012540	DDE superfamily endonuclease; Region: DDE_3; pfam13358
344609012541	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609012542	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609012543	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
344609012544	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
344609012545	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
344609012546	E3 ubiquitin-protein ligase SlrP; Provisional; Region: PRK15370
344609012547	Transposase; Region: HTH_Tnp_1; cl17663
344609012548	putative transposase OrfB; Reviewed; Region: PHA02517
344609012549	HTH-like domain; Region: HTH_21; pfam13276
344609012550	Integrase core domain; Region: rve; pfam00665
344609012551	Integrase core domain; Region: rve_3; pfam13683
344609012552	Shigella flexneri OspC protein; Region: Shigella_OspC; pfam06128
344609012553	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012554	Transposase; Region: HTH_Tnp_1; pfam01527
344609012555	putative transposase OrfB; Reviewed; Region: PHA02517
344609012556	HTH-like domain; Region: HTH_21; pfam13276
344609012557	Integrase core domain; Region: rve; pfam00665
344609012558	Integrase core domain; Region: rve_3; pfam13683
344609012559	Transposase; Region: DEDD_Tnp_IS110; pfam01548
344609012560	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
344609012561	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
344609012562	Integrase core domain; Region: rve; pfam00665
344609012563	Transposase; Region: HTH_Tnp_1; pfam01527
344609012564	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012565	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609012566	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609012567	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609012568	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609012569	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609012570	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609012571	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609012572	hypothetical protein; Validated; Region: PRK07586
344609012573	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
344609012574	ParB-like nuclease domain; Region: ParB; smart00470
344609012575	ParB family; Region: ParB; pfam08775
344609012576	acyl carrier protein; Provisional; Region: acpP; PRK00982
344609012577	Salmonella invasion protein A; Region: SipA; pfam09052
344609012578	Invasion plasmid antigen IpaD; Region: IpaD; cl05827
344609012579	pathogenicity island 1 effector protein SipC; Provisional; Region: PRK15373
344609012580	pathogenicity island 1 effector protein SipB; Provisional; Region: PRK15374
344609012581	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
344609012582	Tetratricopeptide repeat; Region: TPR_3; pfam07720
344609012583	Tetratricopeptide repeat; Region: TPR_3; pfam07720
344609012584	IpaB/EvcA family; Region: IpaB_EvcA; pfam03278
344609012585	chaperone protein SicP; Provisional; Region: PRK15329
344609012586	Enterobacterial virulence protein IpgD; Region: IpgD; pfam05925
344609012587	inositol phosphate phosphatase SopB; Provisional; Region: PRK15378
344609012588	type III secretion chaperone protein SigE; Provisional; Region: PRK15202
344609012589	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
344609012590	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
344609012591	N-acetyl-D-glucosamine binding site [chemical binding]; other site
344609012592	catalytic residue [active]
344609012593	Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; pfam09480
344609012594	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327; cl12363
344609012595	Type III secretion needle MxiH like; Region: MxiH; cl09641
344609012596	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
344609012597	type III secretion apparatus lipoprotein, YscJ/HrcJ family; Region: III_secr_YscJ; TIGR02544
344609012598	type III secretion apparatus protein OrgA/MxiK; Region: OrgA_MxiK; TIGR02555
344609012599	invasion protein OrgA; Provisional; Region: PRK15323
344609012600	invasion protein OrgB; Provisional; Region: PRK15322
344609012601	Pilot protein MxiM; Region: MxiM; pfam11441
344609012602	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
344609012603	type III secretion system outer membrane pore InvG; Provisional; Region: PRK15339
344609012604	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
344609012605	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
344609012606	type III secretion system regulator InvE; Provisional; Region: PRK15338
344609012607	HrpJ-like domain; Region: HrpJ; pfam07201
344609012608	type III secretion system protein InvA; Provisional; Region: PRK15337
344609012609	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; cl07980
344609012610	Invasion protein B family; Region: Invas_SpaK; pfam03519
344609012611	ATP synthase SpaL; Validated; Region: PRK08149
344609012612	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
344609012613	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
344609012614	Walker A motif; other site
344609012615	ATP binding site [chemical binding]; other site
344609012616	Walker B motif; other site
344609012617	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
344609012618	type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796
344609012619	Bacterial export proteins, family 3; Region: Bac_export_3; cl00867
344609012620	type III secretion protein SpaR/YscT/HrcT; Region: fliR_like_III; TIGR01401
344609012621	type III secretion system protein SpaS; Validated; Region: PRK08156
344609012622	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
344609012623	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
344609012624	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609012625	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609012626	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609012627	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609012628	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609012629	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609012630	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609012631	Transposase; Region: HTH_Tnp_1; pfam01527
344609012632	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012633	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012634	Transposase; Region: HTH_Tnp_1; cl17663
344609012635	Group II catalytic intron
344609012636	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609012637	Transposase; Region: DDE_Tnp_ISL3; pfam01610
344609012638	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
344609012639	Transposase; Region: HTH_Tnp_1; cl17663
344609012640	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012641	putative transposase OrfB; Reviewed; Region: PHA02517
344609012642	HTH-like domain; Region: HTH_21; pfam13276
344609012643	Integrase core domain; Region: rve; pfam00665
344609012644	Integrase core domain; Region: rve_3; cl15866
344609012645	Transposase; Region: DDE_Tnp_ISL3; pfam01610
344609012646	EspG protein; Region: EspG; pfam06872
344609012647	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
344609012648	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
344609012649	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
344609012650	Autotransporter beta-domain; Region: Autotransporter; pfam03797
344609012651	Transposase; Region: HTH_Tnp_1; cl17663
344609012652	putative transposase OrfB; Reviewed; Region: PHA02517
344609012653	HTH-like domain; Region: HTH_21; pfam13276
344609012654	Integrase core domain; Region: rve; pfam00665
344609012655	Integrase core domain; Region: rve_3; pfam13683
344609012656	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
344609012657	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
344609012658	active site
344609012659	metal binding site [ion binding]; metal-binding site
344609012660	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
344609012661	Probable transposase; Region: OrfB_IS605; pfam01385
344609012662	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609012663	Transposase; Region: HTH_Tnp_1; pfam01527
344609012664	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012665	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609012666	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
344609012667	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
344609012668	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
344609012669	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
344609012670	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609012671	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609012672	Group II catalytic intron
344609012673	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
344609012674	putative transposase OrfB; Reviewed; Region: PHA02517
344609012675	HTH-like domain; Region: HTH_21; pfam13276
344609012676	Integrase core domain; Region: rve; pfam00665
344609012677	Integrase core domain; Region: rve_3; pfam13683
344609012678	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
344609012679	PRTRC system protein D; Region: PRTRC_D; TIGR03739
344609012680	Mg binding site [ion binding]; other site
344609012681	nucleotide binding site [chemical binding]; other site
344609012682	putative protofilament interface [polypeptide binding]; other site
344609012683	Plasmid stability protein; Region: Plasmid_stab_B; pfam10784
344609012684	IS2 transposase TnpB; Reviewed; Region: PRK09409
344609012685	HTH-like domain; Region: HTH_21; pfam13276
344609012686	Integrase core domain; Region: rve; pfam00665
344609012687	Integrase core domain; Region: rve_3; pfam13683
344609012688	RelB antitoxin; Region: RelB; cl01171
344609012689	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609012690	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
344609012691	PAP2, bacterial acid phosphatase or class A non-specific acid phosphatases. These enzymes catalyze phosphomonoester hydrolysis, with optimal activity in low pH conditions. They are secreted into the periplasmic space, and their physiological role remains...; Region: PAP2_acid_phosphatase; cd03397
344609012692	active site
344609012693	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
344609012694	Integrase core domain; Region: rve; pfam00665
344609012695	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
344609012696	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
344609012697	putative active site [active]
344609012698	putative NTP binding site [chemical binding]; other site
344609012699	putative nucleic acid binding site [nucleotide binding]; other site
344609012700	Transposase; Region: HTH_Tnp_1; cl17663
344609012701	putative transposase OrfB; Reviewed; Region: PHA02517
344609012702	HTH-like domain; Region: HTH_21; pfam13276
344609012703	Integrase core domain; Region: rve; pfam00665
344609012704	Integrase core domain; Region: rve_3; pfam13683
344609012705	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
344609012706	plasmid maintenance protein CcdA; Provisional; Region: PRK13710
344609012707	plasmid maintenance protein CcdB; Provisional; Region: PRK13708
344609012708	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
344609012709	E3 ubiquitin-protein ligase SlrP; Provisional; Region: PRK15370
344609012710	Leucine-rich repeats, bacterial type; Region: LRR_BAC; smart00364
344609012711	RelB antitoxin; Region: RelB; cl01171
344609012712	serine/threonine protein kinase; Provisional; Region: PRK14879
344609012713	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609012714	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
344609012715	putative active site [active]
344609012716	putative metal binding site [ion binding]; other site
344609012717	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
344609012718	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
344609012719	Protein of unknown function (DUF535); Region: DUF535; pfam04393
344609012720	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
344609012721	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
344609012722	putative acyl-acceptor binding pocket; other site
344609012723	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
344609012724	conjugal transfer pilus acetylation protein TraX; Provisional; Region: PRK13706
344609012725	conjugal transfer fertility inhibition protein FinO; Provisional; Region: PRK13754
344609012726	Fertility inhibition protein N terminal; Region: FinO_N; pfam12602
344609012727	FinO bacterial conjugation repressor domain;  the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which...; Region: FinO_conjug_rep; cd00236
344609012728	putative RNA binding sites [nucleotide binding]; other site
344609012729	Haemolysin expression modulating protein; Region: HHA; pfam05321
344609012730	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
344609012731	replication protein; Provisional; Region: PRK13702
344609012732	replication protein; Provisional; Region: PRK13750
344609012733	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
344609012734	Putative transposase; Region: Y2_Tnp; pfam04986
344609012735	Transposase; Region: HTH_Tnp_1; pfam01527
344609012736	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012737	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
344609012738	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
344609012739	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
344609012740	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
344609012741	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
344609012742	Shigella flexneri OspC protein; Region: Shigella_OspC; pfam06128
344609012743	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
344609012744	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
344609012745	Putative transposase; Region: Y2_Tnp; pfam04986
344609012746	Transposase; Region: HTH_Tnp_1; cl17663
344609012747	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012748	putative transposase OrfB; Reviewed; Region: PHA02517
344609012749	HTH-like domain; Region: HTH_21; pfam13276
344609012750	Integrase core domain; Region: rve; pfam00665
344609012751	Integrase core domain; Region: rve_3; pfam13683
344609012752	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
344609012753	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
344609012754	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
344609012755	Transposase; Region: HTH_Tnp_1; pfam01527
344609012756	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
344609012757	Integrase core domain; Region: rve_2; pfam13333
344609012758	Omptin family; Region: Omptin; pfam01278
344609012759	Bacterial mobilisation protein (MobC); Region: MobC; pfam05713
344609012760	MbeD/MobD like; Region: MbeD_MobD; pfam04899
344609012761	Colicin immunity protein; Region: Colicin_im; pfam03857