-- dump date   	20140620_071140
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
929556000001	DnaA N-terminal domain; Region: DnaA_N; pfam11638
929556000002	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
929556000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556000004	Walker A motif; other site
929556000005	ATP binding site [chemical binding]; other site
929556000006	Walker B motif; other site
929556000007	arginine finger; other site
929556000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
929556000009	DnaA box-binding interface [nucleotide binding]; other site
929556000010	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
929556000011	Repair protein; Region: Repair_PSII; pfam04536
929556000012	Repair protein; Region: Repair_PSII; cl01535
929556000013	LemA family; Region: LemA; pfam04011
929556000014	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
929556000015	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
929556000016	DinB superfamily; Region: DinB_2; pfam12867
929556000017	CoA binding domain; Region: CoA_binding_2; pfam13380
929556000018	Acyl ACP desaturase, ferritin-like diiron-binding domain; Region: Acyl_ACP_Desat; cd01050
929556000019	Fatty acid desaturase; Region: FA_desaturase_2; pfam03405
929556000020	homodimer interface [polypeptide binding]; other site
929556000021	putative substrate binding pocket [chemical binding]; other site
929556000022	diiron center [ion binding]; other site
929556000023	Mechanosensitive ion channel; Region: MS_channel; pfam00924
929556000024	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
929556000025	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
929556000026	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
929556000027	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556000028	Coenzyme A binding pocket [chemical binding]; other site
929556000029	Pirin-related protein [General function prediction only]; Region: COG1741
929556000030	Pirin; Region: Pirin; pfam02678
929556000031	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
929556000032	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
929556000033	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556000034	Walker A/P-loop; other site
929556000035	ATP binding site [chemical binding]; other site
929556000036	Q-loop/lid; other site
929556000037	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929556000038	ABC transporter signature motif; other site
929556000039	Walker B; other site
929556000040	ABC transporter; Region: ABC_tran_2; pfam12848
929556000041	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929556000042	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
929556000043	Clp amino terminal domain; Region: Clp_N; pfam02861
929556000044	Clp amino terminal domain; Region: Clp_N; pfam02861
929556000045	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556000046	Walker A motif; other site
929556000047	ATP binding site [chemical binding]; other site
929556000048	Walker B motif; other site
929556000049	arginine finger; other site
929556000050	UvrB/uvrC motif; Region: UVR; pfam02151
929556000051	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556000052	Walker A motif; other site
929556000053	ATP binding site [chemical binding]; other site
929556000054	Walker B motif; other site
929556000055	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
929556000056	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929556000057	Enoyl-(Acyl carrier protein) reductase; Region: adh_short_C2; pfam13561
929556000058	NAD(P) binding site [chemical binding]; other site
929556000059	active site
929556000060	Domain of unknown function (DUF4403); Region: DUF4403; pfam14356
929556000061	trans-2-enoyl-CoA reductase; Provisional; Region: PRK13656
929556000062	NAD(P)H binding domain of trans-2-enoyl-CoA reductase; Region: Eno-Rase_NADH_b; pfam12242
929556000063	Trans-2-enoyl-CoA reductase catalytic region; Region: Enoyl_reductase; pfam12241
929556000064	Enoyl reductase FAD binding domain; Region: Eno-Rase_FAD_bd; pfam07055
929556000065	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
929556000066	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
929556000067	Walker A/P-loop; other site
929556000068	ATP binding site [chemical binding]; other site
929556000069	Q-loop/lid; other site
929556000070	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
929556000071	ABC transporter signature motif; other site
929556000072	Walker B; other site
929556000073	D-loop; other site
929556000074	H-loop/switch region; other site
929556000075	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
929556000076	Flavoprotein; Region: Flavoprotein; pfam02441
929556000077	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
929556000078	RNA polymerase Rpb6; Region: RNA_pol_Rpb6; cl14651
929556000079	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
929556000080	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
929556000081	Transposase; Region: DDE_Tnp_ISL3; pfam01610
929556000082	Pirin-related protein [General function prediction only]; Region: COG1741
929556000083	Pirin; Region: Pirin; pfam02678
929556000084	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
929556000085	Predicted acetyltransferase [General function prediction only]; Region: COG2388
929556000086	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
929556000087	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
929556000088	active site
929556000089	Bacterial SH3 domain; Region: SH3_3; cl17532
929556000090	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
929556000091	NlpC/P60 family; Region: NLPC_P60; pfam00877
929556000092	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
929556000093	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
929556000094	putative active site [active]
929556000095	heme pocket [chemical binding]; other site
929556000096	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556000097	dimer interface [polypeptide binding]; other site
929556000098	phosphorylation site [posttranslational modification]
929556000099	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556000100	ATP binding site [chemical binding]; other site
929556000101	Mg2+ binding site [ion binding]; other site
929556000102	G-X-G motif; other site
929556000103	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556000104	Response regulator receiver domain; Region: Response_reg; pfam00072
929556000105	active site
929556000106	phosphorylation site [posttranslational modification]
929556000107	intermolecular recognition site; other site
929556000108	dimerization interface [polypeptide binding]; other site
929556000109	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
929556000110	DNA binding residues [nucleotide binding]
929556000111	7TMR-DISM extracellular 2; Region: 7TMR-DISMED2; pfam07696
929556000112	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
929556000113	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
929556000114	Histidine kinase; Region: HisKA_2; pfam07568
929556000115	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
929556000116	ATP binding site [chemical binding]; other site
929556000117	Mg2+ binding site [ion binding]; other site
929556000118	G-X-G motif; other site
929556000119	CshA-type fibril repeat; Region: CshA_fibril_rpt; TIGR04225
929556000120	CshA-type fibril repeat; Region: CshA_fibril_rpt; TIGR04225
929556000121	VCBS repeat; Region: VCBS_repeat; TIGR01965
929556000122	CshA-type fibril repeat; Region: CshA_fibril_rpt; TIGR04225
929556000123	VCBS repeat; Region: VCBS_repeat; TIGR01965
929556000124	VCBS repeat; Region: VCBS_repeat; TIGR01965
929556000125	VCBS repeat; Region: VCBS_repeat; TIGR01965
929556000126	VCBS repeat; Region: VCBS_repeat; TIGR01965
929556000127	CshA-type fibril repeat; Region: CshA_fibril_rpt; TIGR04225
929556000128	CshA-type fibril repeat; Region: CshA_fibril_rpt; TIGR04225
929556000129	VCBS repeat; Region: VCBS_repeat; TIGR01965
929556000130	CshA-type fibril repeat; Region: CshA_fibril_rpt; TIGR04225
929556000131	VCBS repeat; Region: VCBS_repeat; TIGR01965
929556000132	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556000133	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
929556000134	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556000135	binding surface
929556000136	Tetratricopeptide repeat; Region: TPR_16; pfam13432
929556000137	TPR motif; other site
929556000138	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556000139	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556000140	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
929556000141	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556000142	ligand binding site [chemical binding]; other site
929556000143	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
929556000144	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
929556000145	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556000146	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
929556000147	Outer membrane efflux protein; Region: OEP; pfam02321
929556000148	Outer membrane efflux protein; Region: OEP; pfam02321
929556000149	Nucleotidyltransferase/DNA polymerase involved in DNA repair [DNA replication, recombination, and repair]; Region: DinP; COG0389
929556000150	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
929556000151	active site
929556000152	DNA binding site [nucleotide binding]
929556000153	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
929556000154	DNA polymerase III, alpha subunit [DNA replication, recombination, and repair]; Region: DnaE; COG0587
929556000155	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III; Region: PHP_PolIIIA; cd07431
929556000156	active site
929556000157	PHP Thumb interface [polypeptide binding]; other site
929556000158	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
929556000159	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
929556000160	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
929556000161	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
929556000162	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
929556000163	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
929556000164	Protein of unknown function (DUF1349); Region: DUF1349; pfam07081
929556000165	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
929556000166	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
929556000167	active site
929556000168	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
929556000169	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
929556000170	putative DNA binding site [nucleotide binding]; other site
929556000171	putative Zn2+ binding site [ion binding]; other site
929556000172	AsnC family; Region: AsnC_trans_reg; pfam01037
929556000173	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
929556000174	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
929556000175	amidase catalytic site [active]
929556000176	Zn binding residues [ion binding]; other site
929556000177	substrate binding site [chemical binding]; other site
929556000178	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
929556000179	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
929556000180	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
929556000181	Rhomboid family; Region: Rhomboid; pfam01694
929556000182	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556000183	binding surface
929556000184	TPR motif; other site
929556000185	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
929556000186	Domain of unknown function DUF20; Region: UPF0118; pfam01594
929556000187	Outer membrane efflux protein; Region: OEP; pfam02321
929556000188	Outer membrane efflux protein; Region: OEP; pfam02321
929556000189	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
929556000190	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
929556000191	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556000192	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
929556000193	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
929556000194	homotrimer interaction site [polypeptide binding]; other site
929556000195	putative active site [active]
929556000196	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556000197	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556000198	ligand binding site [chemical binding]; other site
929556000199	flexible hinge region; other site
929556000200	DoxX; Region: DoxX; pfam07681
929556000201	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
929556000202	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
929556000203	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556000204	catalytic residues [active]
929556000205	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556000206	starch binding outer membrane protein SusD; Region: SusD; cl17845
929556000207	Secretin and TonB N terminus short domain; Region: STN; pfam07660
929556000208	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556000209	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556000210	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
929556000211	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556000212	FecR protein; Region: FecR; pfam04773
929556000213	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
929556000214	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
929556000215	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556000216	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556000217	DNA binding residues [nucleotide binding]
929556000218	Histidine kinase; Region: His_kinase; pfam06580
929556000219	Histidine kinase; Region: His_kinase; pfam06580
929556000220	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
929556000221	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556000222	active site
929556000223	phosphorylation site [posttranslational modification]
929556000224	intermolecular recognition site; other site
929556000225	dimerization interface [polypeptide binding]; other site
929556000226	LytTr DNA-binding domain; Region: LytTR; smart00850
929556000227	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
929556000228	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
929556000229	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
929556000230	TPR repeat; Region: TPR_11; pfam13414
929556000231	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556000232	binding surface
929556000233	TPR motif; other site
929556000234	Tetratricopeptide repeat; Region: TPR_16; pfam13432
929556000235	TPR repeat; Region: TPR_11; pfam13414
929556000236	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556000237	binding surface
929556000238	TPR motif; other site
929556000239	TPR repeat; Region: TPR_11; pfam13414
929556000240	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
929556000241	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556000242	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556000243	DNA binding residues [nucleotide binding]
929556000244	FecR protein; Region: FecR; pfam04773
929556000245	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
929556000246	Secretin and TonB N terminus short domain; Region: STN; pfam07660
929556000247	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556000248	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556000249	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556000250	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556000251	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556000252	SusD family; Region: SusD; pfam07980
929556000253	trehalose synthase; Region: treS_nterm; TIGR02456
929556000254	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
929556000255	active site
929556000256	catalytic site [active]
929556000257	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
929556000258	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
929556000259	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
929556000260	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556000261	active site
929556000262	phosphorylation site [posttranslational modification]
929556000263	intermolecular recognition site; other site
929556000264	dimerization interface [polypeptide binding]; other site
929556000265	LytTr DNA-binding domain; Region: LytTR; smart00850
929556000266	Histidine kinase; Region: His_kinase; pfam06580
929556000267	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556000268	ATP binding site [chemical binding]; other site
929556000269	Mg2+ binding site [ion binding]; other site
929556000270	G-X-G motif; other site
929556000271	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
929556000272	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556000273	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
929556000274	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
929556000275	Ion channel; Region: Ion_trans_2; pfam07885
929556000276	DinB superfamily; Region: DinB_2; pfam12867
929556000277	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556000278	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556000279	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556000280	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
929556000281	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556000282	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556000283	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
929556000284	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
929556000285	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
929556000286	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
929556000287	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
929556000288	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
929556000289	DNA-binding site [nucleotide binding]; DNA binding site
929556000290	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
929556000291	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556000292	homodimer interface [polypeptide binding]; other site
929556000293	catalytic residue [active]
929556000294	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556000295	Coenzyme A binding pocket [chemical binding]; other site
929556000296	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
929556000297	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
929556000298	catalytic residue [active]
929556000299	ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones]; Region: SpoVK; COG0464
929556000300	ATPase family associated with various cellular activities (AAA); Region: AAA; pfam00004
929556000301	Walker A motif; other site
929556000302	ATP binding site [chemical binding]; other site
929556000303	Walker B motif; other site
929556000304	arginine finger; other site
929556000305	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_2; cd09618
929556000306	putative ligand binding site [chemical binding]; other site
929556000307	Cyclomaltodextrinase, N-terminal; Region: Cyc-maltodext_N; pfam09087
929556000308	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
929556000309	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
929556000310	active site
929556000311	catalytic site [active]
929556000312	Cyclo-malto-dextrinase C-terminal domain; Region: Cyc-maltodext_C; pfam10438
929556000313	Histidine kinase; Region: His_kinase; pfam06580
929556000314	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
929556000315	ATP binding site [chemical binding]; other site
929556000316	Mg2+ binding site [ion binding]; other site
929556000317	G-X-G motif; other site
929556000318	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
929556000319	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556000320	active site
929556000321	phosphorylation site [posttranslational modification]
929556000322	intermolecular recognition site; other site
929556000323	dimerization interface [polypeptide binding]; other site
929556000324	LytTr DNA-binding domain; Region: LytTR; smart00850
929556000325	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
929556000326	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929556000327	catalytic residue [active]
929556000328	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556000329	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556000330	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556000331	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556000332	starch binding outer membrane protein SusD; Region: SusD; cl17845
929556000333	Piwi_piwi-like_ProArk: PIWI domain, Piwi-like subfamily found in Archaea and Bacteria. RNA silencing refers to a group of related gene-silencing mechanisms mediated by short RNA molecules, including siRNAs, miRNAs, and heterochromatin-related guide RNAs; Region: Piwi_piwi-like_ProArk; cd04659
929556000334	5' RNA guide strand anchoring site; other site
929556000335	active site
929556000336	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
929556000337	active site residue [active]
929556000338	OsmC-like protein; Region: OsmC; pfam02566
929556000339	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556000340	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556000341	ligand binding site [chemical binding]; other site
929556000342	flexible hinge region; other site
929556000343	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
929556000344	non-specific DNA interactions [nucleotide binding]; other site
929556000345	DNA binding site [nucleotide binding]
929556000346	sequence specific DNA binding site [nucleotide binding]; other site
929556000347	putative cAMP binding site [chemical binding]; other site
929556000348	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
929556000349	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
929556000350	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556000351	catalytic residues [active]
929556000352	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556000353	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556000354	Secretin and TonB N terminus short domain; Region: STN; pfam07660
929556000355	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556000356	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556000357	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556000358	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
929556000359	FecR protein; Region: FecR; pfam04773
929556000360	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
929556000361	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
929556000362	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556000363	DNA binding residues [nucleotide binding]
929556000364	Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]; Region: COG3571
929556000365	Domain of unknown function (DUF4287); Region: DUF4287; pfam14117
929556000366	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_1; cd07818
929556000367	putative hydrophobic ligand binding site [chemical binding]; other site
929556000368	DoxX-like family; Region: DoxX_2; pfam13564
929556000369	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
929556000370	dimer interface [polypeptide binding]; other site
929556000371	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556000372	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_2; cd03138
929556000373	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
929556000374	conserved cys residue [active]
929556000375	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556000376	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556000377	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556000378	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556000379	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
929556000380	Protein of unknown function (DUF3732); Region: DUF3732; pfam12532
929556000381	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
929556000382	Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs; Region: carb_red_PTCR-like_SDR_c; cd05324
929556000383	NADP binding site [chemical binding]; other site
929556000384	substrate binding site [chemical binding]; other site
929556000385	active site
929556000386	Transposase; Region: HTH_Tnp_1; cl17663
929556000387	Helix-turn-helix domain; Region: HTH_18; pfam12833
929556000388	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556000389	Protein of unknown function (DUF541); Region: SIMPL; pfam04402
929556000390	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
929556000391	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
929556000392	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
929556000393	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556000394	Nuclease-related domain; Region: NERD; pfam08378
929556000395	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929556000396	ATP binding site [chemical binding]; other site
929556000397	putative Mg++ binding site [ion binding]; other site
929556000398	helicase superfamily c-terminal domain; Region: HELICc; smart00490
929556000399	nucleotide binding region [chemical binding]; other site
929556000400	ATP-binding site [chemical binding]; other site
929556000401	Domain of unknown function (DUF1837); Region: DUF1837; pfam08878
929556000402	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
929556000403	YWFCY protein; Region: YWFCY; pfam14293
929556000404	AAA-like domain; Region: AAA_10; pfam12846
929556000405	TraM recognition site of TraD and TraG; Region: TraG-D_C; pfam12696
929556000406	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
929556000407	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
929556000408	MPN+ (JAMM) motif; other site
929556000409	Zinc-binding site [ion binding]; other site
929556000410	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556000411	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556000412	ligand binding site [chemical binding]; other site
929556000413	flexible hinge region; other site
929556000414	Protein of unknown function DUF262; Region: DUF262; pfam03235
929556000415	type II restriction m6 adenine DNA methyltransferase, Alw26I/Eco31I/Esp3I family; Region: met_A_Alw26; TIGR02987
929556000416	Methyltransferase domain; Region: Methyltransf_26; pfam13659
929556000417	BsuBI/PstI restriction endonuclease C-terminus; Region: BsuBI_PstI_RE; pfam06616
929556000418	Transposase; Region: HTH_Tnp_1; cl17663
929556000419	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
929556000420	putative transposase OrfB; Reviewed; Region: PHA02517
929556000421	Integrase core domain; Region: rve; pfam00665
929556000422	Integrase core domain; Region: rve_3; cl15866
929556000423	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
929556000424	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556000425	catalytic residues [active]
929556000426	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556000427	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556000428	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
929556000429	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556000430	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556000431	PGAP1-like protein; Region: PGAP1; pfam07819
929556000432	RteC protein; Region: RteC; pfam09357
929556000433	Domain of unknown function (DUF4134); Region: DUF4134; pfam13572
929556000434	Domain of unknown function (DUF4133); Region: DUF4133; pfam13571
929556000435	Bacteroides conjugation system ATPase, TraG family; Region: Bac_Flav_CT_G; TIGR03783
929556000436	Domain of unknown function, B. Theta Gene description (DUF3875); Region: DUF3875; pfam12991
929556000437	Bacteroides conjugative transposon TraJ protein; Region: Bac_Flav_CT_J; TIGR03782
929556000438	Bacteroides conjugative transposon TraK protein; Region: Bac_Flav_CT_K; TIGR03781
929556000439	Bacteroides conjugative transposon TraM protein; Region: Bac_Flav_CT_M; TIGR03779
929556000440	Protein of unknown function (DUF3714); Region: DUF3714; pfam12508
929556000441	Bacteroides conjugative transposon TraN protein; Region: Bac_Flav_CT_N; TIGR03780
929556000442	Domain of unknown function (DUF4138); Region: DUF4138; pfam13595
929556000443	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
929556000444	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
929556000445	catalytic residues [active]
929556000446	catalytic nucleophile [active]
929556000447	Recombinase; Region: Recombinase; pfam07508
929556000448	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
929556000449	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
929556000450	Predicted permeases [General function prediction only]; Region: COG0795
929556000451	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
929556000452	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
929556000453	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
929556000454	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
929556000455	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
929556000456	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
929556000457	dimerization interface [polypeptide binding]; other site
929556000458	active site
929556000459	Family of unknown function (DUF490); Region: DUF490; pfam04357
929556000460	UGMP family protein; Validated; Region: PRK09604
929556000461	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
929556000462	DinB family; Region: DinB; cl17821
929556000463	DinB superfamily; Region: DinB_2; pfam12867
929556000464	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
929556000465	recombinase A; Provisional; Region: recA; PRK09354
929556000466	hexamer interface [polypeptide binding]; other site
929556000467	Walker A motif; other site
929556000468	ATP binding site [chemical binding]; other site
929556000469	Walker B motif; other site
929556000470	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
929556000471	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
929556000472	minor groove reading motif; other site
929556000473	helix-hairpin-helix signature motif; other site
929556000474	substrate binding pocket [chemical binding]; other site
929556000475	active site
929556000476	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
929556000477	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556000478	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556000479	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556000480	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
929556000481	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556000482	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
929556000483	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556000484	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
929556000485	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
929556000486	active site
929556000487	metal binding site [ion binding]; metal-binding site
929556000488	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
929556000489	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
929556000490	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
929556000491	active site
929556000492	Zn binding site [ion binding]; other site
929556000493	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
929556000494	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
929556000495	tetramer interface [polypeptide binding]; other site
929556000496	active site
929556000497	Mg2+/Mn2+ binding site [ion binding]; other site
929556000498	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
929556000499	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
929556000500	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
929556000501	dimerization interface [polypeptide binding]; other site
929556000502	substrate binding pocket [chemical binding]; other site
929556000503	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
929556000504	catalytic residues [active]
929556000505	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
929556000506	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
929556000507	dimer interface [polypeptide binding]; other site
929556000508	decamer (pentamer of dimers) interface [polypeptide binding]; other site
929556000509	catalytic triad [active]
929556000510	peroxidatic and resolving cysteines [active]
929556000511	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
929556000512	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
929556000513	structural tetrad; other site
929556000514	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
929556000515	hypothetical protein; Reviewed; Region: PRK09588
929556000516	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
929556000517	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
929556000518	RNA ligase; Region: RNA_ligase; pfam09414
929556000519	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929556000520	Zn2+ binding site [ion binding]; other site
929556000521	Mg2+ binding site [ion binding]; other site
929556000522	AAA domain; Region: AAA_33; pfam13671
929556000523	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
929556000524	dimer interface [polypeptide binding]; other site
929556000525	putative tRNA-binding site [nucleotide binding]; other site
929556000526	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
929556000527	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556000528	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
929556000529	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
929556000530	NodB motif; other site
929556000531	active site
929556000532	catalytic site [active]
929556000533	metal binding site [ion binding]; metal-binding site
929556000534	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
929556000535	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556000536	ATP binding site [chemical binding]; other site
929556000537	Mg2+ binding site [ion binding]; other site
929556000538	G-X-G motif; other site
929556000539	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
929556000540	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556000541	active site
929556000542	phosphorylation site [posttranslational modification]
929556000543	intermolecular recognition site; other site
929556000544	dimerization interface [polypeptide binding]; other site
929556000545	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556000546	Walker A motif; other site
929556000547	ATP binding site [chemical binding]; other site
929556000548	Walker B motif; other site
929556000549	arginine finger; other site
929556000550	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
929556000551	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
929556000552	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556000553	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
929556000554	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
929556000555	Walker A/P-loop; other site
929556000556	ATP binding site [chemical binding]; other site
929556000557	Q-loop/lid; other site
929556000558	ABC transporter signature motif; other site
929556000559	Walker B; other site
929556000560	D-loop; other site
929556000561	H-loop/switch region; other site
929556000562	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
929556000563	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000564	FtsX-like permease family; Region: FtsX; pfam02687
929556000565	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000566	FtsX-like permease family; Region: FtsX; pfam02687
929556000567	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
929556000568	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000569	FtsX-like permease family; Region: FtsX; pfam02687
929556000570	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000571	FtsX-like permease family; Region: FtsX; pfam02687
929556000572	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000573	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
929556000574	FtsX-like permease family; Region: FtsX; pfam02687
929556000575	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000576	FtsX-like permease family; Region: FtsX; pfam02687
929556000577	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000578	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
929556000579	FtsX-like permease family; Region: FtsX; pfam02687
929556000580	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
929556000581	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000582	FtsX-like permease family; Region: FtsX; pfam02687
929556000583	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000584	FtsX-like permease family; Region: FtsX; pfam02687
929556000585	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000586	FtsX-like permease family; Region: FtsX; pfam02687
929556000587	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
929556000588	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000589	FtsX-like permease family; Region: FtsX; pfam02687
929556000590	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000591	FtsX-like permease family; Region: FtsX; pfam02687
929556000592	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
929556000593	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000594	FtsX-like permease family; Region: FtsX; pfam02687
929556000595	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000596	FtsX-like permease family; Region: FtsX; pfam02687
929556000597	SnoaL-like domain; Region: SnoaL_2; pfam12680
929556000598	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000599	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
929556000600	FtsX-like permease family; Region: FtsX; pfam02687
929556000601	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
929556000602	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000603	FtsX-like permease family; Region: FtsX; pfam02687
929556000604	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000605	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
929556000606	FtsX-like permease family; Region: FtsX; pfam02687
929556000607	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000608	FtsX-like permease family; Region: FtsX; pfam02687
929556000609	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000610	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
929556000611	FtsX-like permease family; Region: FtsX; pfam02687
929556000612	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556000613	FtsX-like permease family; Region: FtsX; pfam02687
929556000614	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
929556000615	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
929556000616	Walker A/P-loop; other site
929556000617	ATP binding site [chemical binding]; other site
929556000618	Q-loop/lid; other site
929556000619	ABC transporter signature motif; other site
929556000620	Walker B; other site
929556000621	D-loop; other site
929556000622	H-loop/switch region; other site
929556000623	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
929556000624	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
929556000625	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
929556000626	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556000627	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GpsA; COG0240
929556000628	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
929556000629	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
929556000630	Protein of unknown function (DUF1294); Region: DUF1294; pfam06961
929556000631	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
929556000632	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
929556000633	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
929556000634	ATP binding site [chemical binding]; other site
929556000635	Mg++ binding site [ion binding]; other site
929556000636	motif III; other site
929556000637	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929556000638	nucleotide binding region [chemical binding]; other site
929556000639	ATP-binding site [chemical binding]; other site
929556000640	RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252
929556000641	RNA binding site [nucleotide binding]; other site
929556000642	Domain of unknown function (DUF4293); Region: DUF4293; pfam14126
929556000643	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
929556000644	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
929556000645	dimerization interface 3.5A [polypeptide binding]; other site
929556000646	active site
929556000647	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
929556000648	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
929556000649	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
929556000650	Walker A/P-loop; other site
929556000651	ATP binding site [chemical binding]; other site
929556000652	Q-loop/lid; other site
929556000653	ABC transporter signature motif; other site
929556000654	Walker B; other site
929556000655	D-loop; other site
929556000656	H-loop/switch region; other site
929556000657	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
929556000658	Beta-lactamase; Region: Beta-lactamase; pfam00144
929556000659	Protein of unknown function (DUF1579); Region: DUF1579; pfam07617
929556000660	Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats [Function unknown]; Region: COG4700
929556000661	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
929556000662	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
929556000663	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929556000664	NAD(P) binding site [chemical binding]; other site
929556000665	active site
929556000666	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
929556000667	classical (c) SDRs; Region: SDR_c; cd05233
929556000668	NAD(P) binding site [chemical binding]; other site
929556000669	active site
929556000670	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
929556000671	CoA binding domain; Region: CoA_binding; smart00881
929556000672	CoA-ligase; Region: Ligase_CoA; pfam00549
929556000673	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
929556000674	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
929556000675	NAD(P) binding site [chemical binding]; other site
929556000676	homotetramer interface [polypeptide binding]; other site
929556000677	homodimer interface [polypeptide binding]; other site
929556000678	active site
929556000679	S-formylglutathione hydrolase; Region: PLN02442
929556000680	Predicted esterase [General function prediction only]; Region: COG0627
929556000681	Surface antigen; Region: Bac_surface_Ag; pfam01103
929556000682	SnoaL-like domain; Region: SnoaL_4; pfam13577
929556000683	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
929556000684	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
929556000685	Predicted membrane protein [Function unknown]; Region: COG2860
929556000686	UPF0126 domain; Region: UPF0126; pfam03458
929556000687	UPF0126 domain; Region: UPF0126; pfam03458
929556000688	enolase; Provisional; Region: eno; PRK00077
929556000689	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
929556000690	dimer interface [polypeptide binding]; other site
929556000691	metal binding site [ion binding]; metal-binding site
929556000692	substrate binding pocket [chemical binding]; other site
929556000693	Septum formation initiator; Region: DivIC; cl17659
929556000694	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
929556000695	Ligand Binding Site [chemical binding]; other site
929556000696	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
929556000697	Ligand Binding Site [chemical binding]; other site
929556000698	Arsenate Reductase (ArsC) family; composed of TRX-fold arsenic reductases and similar proteins including the transcriptional regulator, Spx. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from...; Region: ArsC_family; cd02977
929556000699	ArsC family; Region: ArsC; pfam03960
929556000700	catalytic residue [active]
929556000701	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
929556000702	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
929556000703	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
929556000704	catalytic site [active]
929556000705	subunit interface [polypeptide binding]; other site
929556000706	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
929556000707	oligomerization interface [polypeptide binding]; other site
929556000708	active site
929556000709	metal binding site [ion binding]; metal-binding site
929556000710	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
929556000711	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
929556000712	active site
929556000713	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
929556000714	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
929556000715	7TMR-DISM extracellular 2; Region: 7TMR-DISMED2; pfam07696
929556000716	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
929556000717	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
929556000718	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556000719	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556000720	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556000721	TonB-dependent Receptor Plug Domain; Region: Plug; cl08461
929556000722	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556000723	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556000724	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556000725	SusD family; Region: SusD; pfam07980
929556000726	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
929556000727	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
929556000728	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
929556000729	7TMR-DISM extracellular 2; Region: 7TMR-DISMED2; pfam07696
929556000730	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
929556000731	Protein of unknown function (DUF904); Region: DUF904; pfam06005
929556000732	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
929556000733	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556000734	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556000735	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556000736	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
929556000737	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556000738	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556000739	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
929556000740	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
929556000741	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
929556000742	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
929556000743	active site
929556000744	catalytic residues [active]
929556000745	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
929556000746	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
929556000747	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
929556000748	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
929556000749	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
929556000750	isocitrate dehydrogenase; Validated; Region: PRK08299
929556000751	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
929556000752	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
929556000753	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
929556000754	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
929556000755	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
929556000756	active site
929556000757	cytochrome c nitrate reductase, small subunit; Region: cytochr_NrfH; TIGR03153
929556000758	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
929556000759	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
929556000760	ResB-like family; Region: ResB; pfam05140
929556000761	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
929556000762	Domain of unknown function (DUF4104); Region: DUF4104; pfam13372
929556000763	aminotransferase, LLPSF_NHT_00031 family; Region: NHT_00031; TIGR04181
929556000764	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
929556000765	inhibitor-cofactor binding pocket; inhibition site
929556000766	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556000767	catalytic residue [active]
929556000768	Bacterial sugar transferase; Region: Bac_transf; pfam02397
929556000769	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
929556000770	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
929556000771	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
929556000772	NAD(P) binding site [chemical binding]; other site
929556000773	homodimer interface [polypeptide binding]; other site
929556000774	substrate binding site [chemical binding]; other site
929556000775	active site
929556000776	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
929556000777	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
929556000778	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556000779	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
929556000780	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14970
929556000781	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556000782	Walker A motif; other site
929556000783	ATP binding site [chemical binding]; other site
929556000784	Walker B motif; other site
929556000785	arginine finger; other site
929556000786	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
929556000787	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
929556000788	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
929556000789	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
929556000790	TrkA-C domain; Region: TrkA_C; pfam02080
929556000791	TrkA-C domain; Region: TrkA_C; pfam02080
929556000792	Suppressor of fused protein (SUFU); Region: SUFU; pfam05076
929556000793	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
929556000794	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
929556000795	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
929556000796	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
929556000797	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
929556000798	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
929556000799	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
929556000800	Transglycosylase; Region: Transgly; cl17702
929556000801	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
929556000802	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
929556000803	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556000804	S-adenosylmethionine binding site [chemical binding]; other site
929556000805	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
929556000806	PAS domain; Region: PAS; smart00091
929556000807	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
929556000808	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
929556000809	DNA binding residues [nucleotide binding]
929556000810	dimerization interface [polypeptide binding]; other site
929556000811	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
929556000812	Cysteine-rich domain; Region: CCG; pfam02754
929556000813	Cysteine-rich domain; Region: CCG; pfam02754
929556000814	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
929556000815	4Fe-4S binding domain; Region: Fer4; cl02805
929556000816	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
929556000817	thymidine kinase; Provisional; Region: PRK04296
929556000818	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
929556000819	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
929556000820	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
929556000821	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
929556000822	rod shape-determining protein MreC; Provisional; Region: PRK13922
929556000823	rod shape-determining protein MreC; Region: MreC; pfam04085
929556000824	rod shape-determining protein MreB; Provisional; Region: PRK13927
929556000825	MreB and similar proteins; Region: MreB_like; cd10225
929556000826	nucleotide binding site [chemical binding]; other site
929556000827	Mg binding site [ion binding]; other site
929556000828	putative protofilament interaction site [polypeptide binding]; other site
929556000829	RodZ interaction site [polypeptide binding]; other site
929556000830	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
929556000831	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
929556000832	purine monophosphate binding site [chemical binding]; other site
929556000833	dimer interface [polypeptide binding]; other site
929556000834	putative catalytic residues [active]
929556000835	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
929556000836	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
929556000837	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
929556000838	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
929556000839	active site
929556000840	substrate binding site [chemical binding]; other site
929556000841	cosubstrate binding site; other site
929556000842	catalytic site [active]
929556000843	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
929556000844	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
929556000845	active site
929556000846	nucleophile elbow; other site
929556000847	Surface antigen; Region: Bac_surface_Ag; pfam01103
929556000848	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
929556000849	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
929556000850	DNA-binding site [nucleotide binding]; DNA binding site
929556000851	Predicted membrane protein [Function unknown]; Region: COG2860
929556000852	UPF0126 domain; Region: UPF0126; pfam03458
929556000853	UPF0126 domain; Region: UPF0126; pfam03458
929556000854	4-hydroxyphenylpyruvate dioxygenase; Region: 4HPPD; TIGR01263
929556000855	N-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and hydroxymandelate Synthase (HmaS); Region: HPPD_N_like; cd08342
929556000856	dimer interface [polypeptide binding]; other site
929556000857	C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS); Region: HPPD_C_like; cd07250
929556000858	active site
929556000859	Fe binding site [ion binding]; other site
929556000860	homogentisate 1,2-dioxygenase; Region: HgmA; cl17306
929556000861	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
929556000862	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
929556000863	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
929556000864	four helix bundle protein; Region: TIGR02436
929556000865	Flavin Reductases; Region: FlaRed; cl00801
929556000866	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
929556000867	alpha-glucan phosphorylases; Region: more_P_ylases; TIGR02094
929556000868	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
929556000869	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
929556000870	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
929556000871	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
929556000872	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
929556000873	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
929556000874	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
929556000875	Uncharacterized conserved protein [Function unknown]; Region: COG3391
929556000876	Zinc dependent phospholipase C/S1-P1 nuclease; Region: ZnPC_S1P1; cd10981
929556000877	Zn binding site [ion binding]; other site
929556000878	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
929556000879	homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392
929556000880	OAH/OAS sulfhydrylase; Region: OAH_OAS_sulfhy; TIGR01326
929556000881	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
929556000882	homodimer interface [polypeptide binding]; other site
929556000883	substrate-cofactor binding pocket; other site
929556000884	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556000885	catalytic residue [active]
929556000886	DNA polymerase III subunit beta; Validated; Region: PRK05643
929556000887	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
929556000888	putative DNA binding surface [nucleotide binding]; other site
929556000889	dimer interface [polypeptide binding]; other site
929556000890	beta-clamp/clamp loader binding surface; other site
929556000891	beta-clamp/translesion DNA polymerase binding surface; other site
929556000892	gliding-associated putative ABC transporter substrate-binding component GldG; Region: GldG; TIGR03521
929556000893	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
929556000894	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
929556000895	gliding motility-associated ABC transporter ATP-binding subunit GldA; Region: GldA_ABC_ATP; TIGR03522
929556000896	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
929556000897	Walker A/P-loop; other site
929556000898	ATP binding site [chemical binding]; other site
929556000899	Q-loop/lid; other site
929556000900	ABC transporter signature motif; other site
929556000901	Walker B; other site
929556000902	D-loop; other site
929556000903	H-loop/switch region; other site
929556000904	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
929556000905	glycyl-tRNA synthetase; Provisional; Region: PRK04173
929556000906	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
929556000907	motif 1; other site
929556000908	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
929556000909	active site
929556000910	motif 2; other site
929556000911	motif 3; other site
929556000912	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
929556000913	anticodon binding site; other site
929556000914	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
929556000915	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
929556000916	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556000917	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
929556000918	Penicillinase repressor; Region: Pencillinase_R; pfam03965
929556000919	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
929556000920	Domain of unknown function (DUF4349); Region: DUF4349; pfam14257
929556000921	phenylalanine 4-monooxygenase; Provisional; Region: PRK14056
929556000922	Biopterin-dependent aromatic amino acid hydroxylase; a family of non-heme, iron(II)-dependent enzymes that includes prokaryotic and eukaryotic phenylalanine-4-hydroxylase (PheOH), eukaryotic tyrosine hydroxylase (TyrOH) and eukaryotic tryptophan...; Region: arom_aa_hydroxylase; cl01244
929556000923	cofactor binding site; other site
929556000924	metal binding site [ion binding]; metal-binding site
929556000925	classical (c) SDRs; Region: SDR_c; cd05233
929556000926	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
929556000927	NAD(P) binding site [chemical binding]; other site
929556000928	active site
929556000929	hypothetical protein; Reviewed; Region: PRK00024
929556000930	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
929556000931	MPN+ (JAMM) motif; other site
929556000932	Zinc-binding site [ion binding]; other site
929556000933	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
929556000934	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
929556000935	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
929556000936	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556000937	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
929556000938	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
929556000939	N-terminal plug; other site
929556000940	ligand-binding site [chemical binding]; other site
929556000941	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
929556000942	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
929556000943	putative tRNA-binding site [nucleotide binding]; other site
929556000944	B3/4 domain; Region: B3_4; pfam03483
929556000945	tRNA synthetase B5 domain; Region: B5; pfam03484
929556000946	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
929556000947	dimer interface [polypeptide binding]; other site
929556000948	motif 1; other site
929556000949	motif 3; other site
929556000950	motif 2; other site
929556000951	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
929556000952	Cell division protein ZapA; Region: ZapA; pfam05164
929556000953	phosphodiesterase; Provisional; Region: PRK12704
929556000954	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929556000955	Zn2+ binding site [ion binding]; other site
929556000956	Mg2+ binding site [ion binding]; other site
929556000957	Protein of unknown function (DUF962); Region: DUF962; cl01879
929556000958	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556000959	TonB-dependent receptor; Region: TonB-Xanth-Caul; TIGR01782
929556000960	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556000961	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Region: LPLAT_ACT14924-like; cd07986
929556000962	putative acyl-acceptor binding pocket; other site
929556000963	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
929556000964	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
929556000965	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
929556000966	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
929556000967	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929556000968	active site
929556000969	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
929556000970	Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158
929556000971	FAD binding site [chemical binding]; other site
929556000972	homotetramer interface [polypeptide binding]; other site
929556000973	substrate binding pocket [chemical binding]; other site
929556000974	catalytic base [active]
929556000975	YhhN-like protein; Region: YhhN; pfam07947
929556000976	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
929556000977	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
929556000978	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
929556000979	active site
929556000980	DNA binding site [nucleotide binding]
929556000981	Int/Topo IB signature motif; other site
929556000982	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
929556000983	30S subunit binding site; other site
929556000984	elongation factor Tu; Reviewed; Region: PRK12735
929556000985	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
929556000986	G1 box; other site
929556000987	GEF interaction site [polypeptide binding]; other site
929556000988	GTP/Mg2+ binding site [chemical binding]; other site
929556000989	Switch I region; other site
929556000990	G2 box; other site
929556000991	G3 box; other site
929556000992	Switch II region; other site
929556000993	G4 box; other site
929556000994	G5 box; other site
929556000995	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
929556000996	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
929556000997	Antibiotic Binding Site [chemical binding]; other site
929556000998	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
929556000999	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
929556001000	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
929556001001	putative homodimer interface [polypeptide binding]; other site
929556001002	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
929556001003	heterodimer interface [polypeptide binding]; other site
929556001004	homodimer interface [polypeptide binding]; other site
929556001005	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
929556001006	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
929556001007	23S rRNA interface [nucleotide binding]; other site
929556001008	L7/L12 interface [polypeptide binding]; other site
929556001009	putative thiostrepton binding site; other site
929556001010	L25 interface [polypeptide binding]; other site
929556001011	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
929556001012	mRNA/rRNA interface [nucleotide binding]; other site
929556001013	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
929556001014	23S rRNA interface [nucleotide binding]; other site
929556001015	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
929556001016	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
929556001017	core dimer interface [polypeptide binding]; other site
929556001018	peripheral dimer interface [polypeptide binding]; other site
929556001019	L10 interface [polypeptide binding]; other site
929556001020	L11 interface [polypeptide binding]; other site
929556001021	putative EF-Tu interaction site [polypeptide binding]; other site
929556001022	putative EF-G interaction site [polypeptide binding]; other site
929556001023	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
929556001024	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
929556001025	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
929556001026	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
929556001027	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
929556001028	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
929556001029	RPB3 interaction site [polypeptide binding]; other site
929556001030	RPB1 interaction site [polypeptide binding]; other site
929556001031	RPB11 interaction site [polypeptide binding]; other site
929556001032	RPB10 interaction site [polypeptide binding]; other site
929556001033	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
929556001034	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
929556001035	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
929556001036	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
929556001037	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
929556001038	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
929556001039	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
929556001040	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
929556001041	DNA binding site [nucleotide binding]
929556001042	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
929556001043	Smr domain; Region: Smr; pfam01713
929556001044	Protein of unknown function (DUF3467); Region: DUF3467; pfam11950
929556001045	Part of AAA domain; Region: AAA_19; pfam13245
929556001046	Acyl-protein synthetase, LuxE; Region: LuxE; pfam04443
929556001047	Protein related to penicillin acylase [General function prediction only]; Region: COG2366
929556001048	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
929556001049	Penicillin G acylase (PGA) belongs to a family of beta-lactam acylases that includes cephalosporin acylase (CA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_PGA_like; cd03747
929556001050	active site
929556001051	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556001052	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556001053	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556001054	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
929556001055	beta-phosphoglucomutase; Region: bPGM; TIGR01990
929556001056	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929556001057	motif II; other site
929556001058	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
929556001059	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
929556001060	Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized...; Region: GH31_glucosidase_II_MalA; cd06604
929556001061	trimer interface [polypeptide binding]; other site
929556001062	active site
929556001063	homohexamer (dimer of homotrimer) interface [polypeptide binding]; other site
929556001064	catalytic site [active]
929556001065	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
929556001066	putative hydrophobic ligand binding site [chemical binding]; other site
929556001067	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
929556001068	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_2; cd03138
929556001069	conserved cys residue [active]
929556001070	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556001071	YCII-related domain; Region: YCII; pfam03795
929556001072	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310); Region: DUF2310; cl02380
929556001073	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
929556001074	Outer membrane efflux protein; Region: OEP; pfam02321
929556001075	Outer membrane efflux protein; Region: OEP; pfam02321
929556001076	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
929556001077	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
929556001078	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556001079	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
929556001080	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929556001081	Soluble P-type ATPase [General function prediction only]; Region: COG4087
929556001082	glycogen branching enzyme; Provisional; Region: PRK12313
929556001083	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
929556001084	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
929556001085	active site
929556001086	catalytic site [active]
929556001087	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
929556001088	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
929556001089	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
929556001090	Beta-lactamase; Region: Beta-lactamase; pfam00144
929556001091	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
929556001092	Cupin domain; Region: Cupin_2; cl17218
929556001093	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
929556001094	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556001095	Coenzyme A binding pocket [chemical binding]; other site
929556001096	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4339
929556001097	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556001098	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556001099	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556001100	DinB family; Region: DinB; cl17821
929556001101	DinB superfamily; Region: DinB_2; pfam12867
929556001102	Predicted membrane protein (DUF2306); Region: DUF2306; cl02232
929556001103	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556001104	TPR motif; other site
929556001105	TPR repeat; Region: TPR_11; pfam13414
929556001106	binding surface
929556001107	TPR repeat; Region: TPR_11; pfam13414
929556001108	Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; Region: IPT; cl15674
929556001109	Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; Region: IPT; cl15674
929556001110	Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; Region: IPT; cl15674
929556001111	Bacterial proteins similar to Porphyromonas gingivalis HmuY; Region: HmuY; cd12105
929556001112	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
929556001113	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
929556001114	N-terminal plug; other site
929556001115	ligand-binding site [chemical binding]; other site
929556001116	DinB superfamily; Region: DinB_2; pfam12867
929556001117	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
929556001118	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
929556001119	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
929556001120	6-phosphofructokinase; Provisional; Region: PRK03202
929556001121	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
929556001122	active site
929556001123	ADP/pyrophosphate binding site [chemical binding]; other site
929556001124	dimerization interface [polypeptide binding]; other site
929556001125	allosteric effector site; other site
929556001126	fructose-1,6-bisphosphate binding site; other site
929556001127	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
929556001128	nudix motif; other site
929556001129	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
929556001130	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
929556001131	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556001132	Coenzyme A binding pocket [chemical binding]; other site
929556001133	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
929556001134	X25 domain of Bacillus acidopullulyticus pullulanase and similar proteins; Region: X25_BaPul_like; cd12962
929556001135	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
929556001136	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556001137	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
929556001138	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
929556001139	N-terminal plug; other site
929556001140	ligand-binding site [chemical binding]; other site
929556001141	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
929556001142	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
929556001143	putative active site [active]
929556001144	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
929556001145	malate dehydrogenase; Reviewed; Region: PRK06223
929556001146	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
929556001147	NAD(P) binding site [chemical binding]; other site
929556001148	dimer interface [polypeptide binding]; other site
929556001149	tetramer (dimer of dimers) interface [polypeptide binding]; other site
929556001150	substrate binding site [chemical binding]; other site
929556001151	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
929556001152	catalytic motif [active]
929556001153	Catalytic residue [active]
929556001154	CHRD domain; Region: CHRD; pfam07452
929556001155	A domain in the BMP inhibitor chordin and in microbial proteins; Region: CHRD; smart00754
929556001156	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
929556001157	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556001158	ATP binding site [chemical binding]; other site
929556001159	Mg2+ binding site [ion binding]; other site
929556001160	G-X-G motif; other site
929556001161	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
929556001162	anchoring element; other site
929556001163	dimer interface [polypeptide binding]; other site
929556001164	ATP binding site [chemical binding]; other site
929556001165	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
929556001166	active site
929556001167	putative metal-binding site [ion binding]; other site
929556001168	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
929556001169	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
929556001170	iron-sulfur cluster [ion binding]; other site
929556001171	[2Fe-2S] cluster binding site [ion binding]; other site
929556001172	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
929556001173	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
929556001174	RNA binding surface [nucleotide binding]; other site
929556001175	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
929556001176	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
929556001177	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
929556001178	trimer interface [polypeptide binding]; other site
929556001179	active site
929556001180	substrate binding site [chemical binding]; other site
929556001181	CoA binding site [chemical binding]; other site
929556001182	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
929556001183	metal binding triad [ion binding]; metal-binding site
929556001184	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
929556001185	tRNA adenylyltransferase; Region: tRNA_CCA_actino; TIGR02692
929556001186	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
929556001187	active site
929556001188	NTP binding site [chemical binding]; other site
929556001189	metal binding triad [ion binding]; metal-binding site
929556001190	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
929556001191	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929556001192	Zn2+ binding site [ion binding]; other site
929556001193	Mg2+ binding site [ion binding]; other site
929556001194	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
929556001195	Inner membrane protein CreD; Region: CreD; pfam06123
929556001196	Transmembrane exosortase (Exosortase_EpsH); Region: Exosortase_EpsH; pfam09721
929556001197	exosortase/archaeosortase family protein; Region: exo_archaeo; TIGR04178
929556001198	Vault protein inter-alpha-trypsin domain; Region: VIT; cl02699
929556001199	Winged helix DNA-binding domain; Region: HTH_34; pfam13601
929556001200	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
929556001201	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
929556001202	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
929556001203	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
929556001204	putative active site [active]
929556001205	putative CoA binding site [chemical binding]; other site
929556001206	nudix motif; other site
929556001207	metal binding site [ion binding]; metal-binding site
929556001208	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556001209	putative transporter; Provisional; Region: PRK10504
929556001210	putative substrate translocation pore; other site
929556001211	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556001212	alpha-galactosidase; Region: PLN02808; cl17638
929556001213	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
929556001214	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
929556001215	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
929556001216	Phosphoenolpyruvate:glucose-phosphotransferase regulator; Region: MtfA; cl01267
929556001217	SnoaL-like domain; Region: SnoaL_2; pfam12680
929556001218	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
929556001219	Domain of unknown function (DUF3471); Region: DUF3471; pfam11954
929556001220	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
929556001221	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
929556001222	N-terminal plug; other site
929556001223	ligand-binding site [chemical binding]; other site
929556001224	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
929556001225	Putative water exit pathway; other site
929556001226	Binuclear center (active site) [active]
929556001227	K-pathway; other site
929556001228	Putative proton exit pathway; other site
929556001229	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
929556001230	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556001231	ligand binding site [chemical binding]; other site
929556001232	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
929556001233	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929556001234	FeS/SAM binding site; other site
929556001235	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
929556001236	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
929556001237	active site
929556001238	PHP Thumb interface [polypeptide binding]; other site
929556001239	metal binding site [ion binding]; metal-binding site
929556001240	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
929556001241	generic binding surface II; other site
929556001242	generic binding surface I; other site
929556001243	Autotransporter beta-domain; Region: Autotransporter; cl17461
929556001244	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
929556001245	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556001246	catalytic residues [active]
929556001247	Protein of unknown function DUF58; Region: DUF58; pfam01882
929556001248	von Willebrand factor type A domain; Region: VWA_2; pfam13519
929556001249	metal ion-dependent adhesion site (MIDAS); other site
929556001250	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556001251	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556001252	dimer interface [polypeptide binding]; other site
929556001253	phosphorylation site [posttranslational modification]
929556001254	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556001255	ATP binding site [chemical binding]; other site
929556001256	Mg2+ binding site [ion binding]; other site
929556001257	G-X-G motif; other site
929556001258	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929556001259	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556001260	active site
929556001261	phosphorylation site [posttranslational modification]
929556001262	intermolecular recognition site; other site
929556001263	dimerization interface [polypeptide binding]; other site
929556001264	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929556001265	DNA binding site [nucleotide binding]
929556001266	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
929556001267	Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992
929556001268	inhibitor-cofactor binding pocket; inhibition site
929556001269	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556001270	catalytic residue [active]
929556001271	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
929556001272	Uncharacterized subfamily of the Thermotoga maritima CorA-like family; Region: TmCorA-like_u3; cd12832
929556001273	oligomer interface [polypeptide binding]; other site
929556001274	metal binding site [ion binding]; metal-binding site
929556001275	putative Cl binding site [ion binding]; other site
929556001276	basic sphincter; other site
929556001277	hydrophobic gate; other site
929556001278	periplasmic entrance; other site
929556001279	hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959
929556001280	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
929556001281	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556001282	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556001283	DNA binding residues [nucleotide binding]
929556001284	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
929556001285	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
929556001286	PYR/PP interface [polypeptide binding]; other site
929556001287	dimer interface [polypeptide binding]; other site
929556001288	TPP binding site [chemical binding]; other site
929556001289	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
929556001290	transketolase; Reviewed; Region: PRK05899
929556001291	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
929556001292	TPP-binding site [chemical binding]; other site
929556001293	dimer interface [polypeptide binding]; other site
929556001294	Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272
929556001295	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
929556001296	HD domain; Region: HD_3; pfam13023
929556001297	aldehyde dehydrogenase family protein; Provisional; Region: PTZ00381
929556001298	Bacillus subtilis aldehyde dehydrogenase ywdH-like; Region: ALDH_YwdH-P39616; cd07136
929556001299	NAD(P) binding site [chemical binding]; other site
929556001300	catalytic residues [active]
929556001301	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
929556001302	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
929556001303	catalytic triad [active]
929556001304	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
929556001305	Peptidase family M23; Region: Peptidase_M23; pfam01551
929556001306	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
929556001307	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
929556001308	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
929556001309	K+ potassium transporter; Region: K_trans; pfam02705
929556001310	amino acid transporter; Region: 2A0306; TIGR00909
929556001311	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
929556001312	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
929556001313	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
929556001314	active site
929556001315	Zinc-dependent metalloprotease, pappalysin_like subfamily. The pregnancy-associated plasma protein A (PAPP-A or pappalysin-1) cleaves insulin-like growth factor-binding proteins 4 and 5, thereby promoting cell growth by releasing bound growth factor; Region: ZnMc_pappalysin_like; cd04275
929556001316	active site
929556001317	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_1; cd09606
929556001318	oligoendopeptidase, M3 family; Region: M3_not_pepF; TIGR02289
929556001319	active site
929556001320	Zn binding site [ion binding]; other site
929556001321	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
929556001322	UbiA prenyltransferase family; Region: UbiA; pfam01040
929556001323	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
929556001324	G1 box; other site
929556001325	GTP/Mg2+ binding site [chemical binding]; other site
929556001326	Switch I region; other site
929556001327	G2 box; other site
929556001328	G3 box; other site
929556001329	Switch II region; other site
929556001330	G4 box; other site
929556001331	G5 box; other site
929556001332	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
929556001333	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556001334	S-adenosylmethionine binding site [chemical binding]; other site
929556001335	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
929556001336	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
929556001337	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
929556001338	putative NAD(P) binding site [chemical binding]; other site
929556001339	homotetramer interface [polypeptide binding]; other site
929556001340	homodimer interface [polypeptide binding]; other site
929556001341	active site
929556001342	Yqey-like protein; Region: YqeY; pfam09424
929556001343	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
929556001344	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
929556001345	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
929556001346	NAD kinase [Coenzyme metabolism]; Region: nadF; cl01255
929556001347	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03708
929556001348	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
929556001349	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
929556001350	catalytic residue [active]
929556001351	putative FPP diphosphate  binding site; other site
929556001352	putative FPP binding hydrophobic cleft; other site
929556001353	dimer interface [polypeptide binding]; other site
929556001354	putative IPP diphosphate binding site; other site
929556001355	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
929556001356	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
929556001357	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
929556001358	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
929556001359	Surface antigen; Region: Bac_surface_Ag; pfam01103
929556001360	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
929556001361	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
929556001362	TQO small subunit DoxD; Region: DoxD; pfam04173
929556001363	TQO small subunit DoxA; Region: DoxA; pfam07680
929556001364	DsrE/DsrF-like family; Region: DrsE; cl00672
929556001365	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
929556001366	Uncharacterized conserved protein (COG2071); Region: DUF2071; pfam09844
929556001367	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
929556001368	Helix-turn-helix domain; Region: HTH_18; pfam12833
929556001369	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556001370	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
929556001371	putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212
929556001372	beta-lactamase TEM; Provisional; Region: PRK15442
929556001373	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
929556001374	TPR repeat; Region: TPR_11; pfam13414
929556001375	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556001376	binding surface
929556001377	TPR motif; other site
929556001378	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556001379	binding surface
929556001380	TPR repeat; Region: TPR_11; pfam13414
929556001381	TPR motif; other site
929556001382	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
929556001383	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
929556001384	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556001385	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556001386	DNA binding residues [nucleotide binding]
929556001387	Protein of unknown function (DUF1569); Region: DUF1569; pfam07606
929556001388	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
929556001389	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556001390	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556001391	DNA binding residues [nucleotide binding]
929556001392	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
929556001393	FecR protein; Region: FecR; pfam04773
929556001394	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556001395	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556001396	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556001397	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
929556001398	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556001399	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556001400	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556001401	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
929556001402	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556001403	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
929556001404	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
929556001405	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
929556001406	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
929556001407	active site
929556001408	Protein of unknown function (DUF1349); Region: DUF1349; cl01397
929556001409	Protein of unknown function (DUF1440); Region: DUF1440; cl01380
929556001410	DinB superfamily; Region: DinB_2; pfam12867
929556001411	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
929556001412	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556001413	active site
929556001414	phosphorylation site [posttranslational modification]
929556001415	intermolecular recognition site; other site
929556001416	dimerization interface [polypeptide binding]; other site
929556001417	LytTr DNA-binding domain; Region: LytTR; pfam04397
929556001418	Histidine kinase; Region: His_kinase; pfam06580
929556001419	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
929556001420	ABC-type multidrug transport system, ATPase component; Region: ABC_drug_resistance_like; cd03264
929556001421	Walker A/P-loop; other site
929556001422	ATP binding site [chemical binding]; other site
929556001423	Q-loop/lid; other site
929556001424	ABC transporter signature motif; other site
929556001425	Walker B; other site
929556001426	D-loop; other site
929556001427	H-loop/switch region; other site
929556001428	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
929556001429	ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only]; Region: NosY; COG1277
929556001430	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
929556001431	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
929556001432	Zn binding site [ion binding]; other site
929556001433	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
929556001434	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
929556001435	Helix-turn-helix domain; Region: HTH_18; pfam12833
929556001436	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556001437	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_8; cd07246
929556001438	putative dimer interface [polypeptide binding]; other site
929556001439	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556001440	Domain of unknown function DUF11; Region: DUF11; pfam01345
929556001441	Domain of unknown function DUF11; Region: DUF11; cl17728
929556001442	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556001443	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
929556001444	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556001445	Coenzyme A binding pocket [chemical binding]; other site
929556001446	Catalytic domain of glycoside hydrolase (GH) families 38 and 57, lactam utilization protein LamB/YcsF family proteins, YdjC-family proteins, and similar proteins; Region: GH38-57_N_LamB_YdjC_SF; cl17191
929556001447	Glyco_18 domain; Region: Glyco_18; smart00636
929556001448	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
929556001449	active site
929556001450	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
929556001451	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
929556001452	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
929556001453	Putative FMN-binding domain; Region: FMN_bind_2; pfam04299
929556001454	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
929556001455	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929556001456	NAD(P) binding site [chemical binding]; other site
929556001457	active site
929556001458	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556001459	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556001460	ligand binding site [chemical binding]; other site
929556001461	flexible hinge region; other site
929556001462	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
929556001463	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
929556001464	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556001465	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
929556001466	Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]; Region: GadB; COG0076
929556001467	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929556001468	catalytic residue [active]
929556001469	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
929556001470	amphipathic channel; other site
929556001471	Asn-Pro-Ala signature motifs; other site
929556001472	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
929556001473	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
929556001474	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
929556001475	4Fe-4S binding domain; Region: Fer4; pfam00037
929556001476	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
929556001477	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
929556001478	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
929556001479	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
929556001480	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
929556001481	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
929556001482	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
929556001483	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
929556001484	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
929556001485	hydroxyglutarate oxidase; Provisional; Region: PRK11728
929556001486	Cache domain; Region: Cache_2; cl07034
929556001487	Histidine kinase; Region: His_kinase; pfam06580
929556001488	Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_2; cd04276
929556001489	active site
929556001490	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556001491	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556001492	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556001493	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
929556001494	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556001495	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556001496	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
929556001497	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556001498	active site
929556001499	phosphorylation site [posttranslational modification]
929556001500	intermolecular recognition site; other site
929556001501	dimerization interface [polypeptide binding]; other site
929556001502	LytTr DNA-binding domain; Region: LytTR; smart00850
929556001503	Surface antigen; Region: Bac_surface_Ag; pfam01103
929556001504	Predicted amidohydrolase [General function prediction only]; Region: COG0388
929556001505	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
929556001506	active site
929556001507	catalytic triad [active]
929556001508	dimer interface [polypeptide binding]; other site
929556001509	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
929556001510	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
929556001511	NADP binding site [chemical binding]; other site
929556001512	dimer interface [polypeptide binding]; other site
929556001513	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
929556001514	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
929556001515	putative active site; other site
929556001516	catalytic triad [active]
929556001517	putative dimer interface [polypeptide binding]; other site
929556001518	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
929556001519	four helix bundle protein; Region: TIGR02436
929556001520	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
929556001521	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
929556001522	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
929556001523	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
929556001524	Glutamine phosphoribosylpyrophosphate amidotransferase [Nucleotide transport and metabolism]; Region: PurF; COG0034
929556001525	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
929556001526	active site
929556001527	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
929556001528	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556001529	DNA binding residues [nucleotide binding]
929556001530	FecR protein; Region: FecR; pfam04773
929556001531	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
929556001532	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556001533	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556001534	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556001535	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556001536	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556001537	Tyrosine phosphatase family; Region: Y_phosphatase2; pfam03162
929556001538	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556001539	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
929556001540	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
929556001541	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
929556001542	catalytic motif [active]
929556001543	Zn binding site [ion binding]; other site
929556001544	GMP synthase; Reviewed; Region: guaA; PRK00074
929556001545	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
929556001546	AMP/PPi binding site [chemical binding]; other site
929556001547	candidate oxyanion hole; other site
929556001548	catalytic triad [active]
929556001549	potential glutamine specificity residues [chemical binding]; other site
929556001550	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
929556001551	ATP Binding subdomain [chemical binding]; other site
929556001552	Ligand Binding sites [chemical binding]; other site
929556001553	Dimerization subdomain; other site
929556001554	Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type I periplasmic binding fold protein superfamily; Region: PBP1_ABC_transporter_LIVBP_like; cd06268
929556001555	ligand binding site [chemical binding]; other site
929556001556	tRNA and rRNA cytosine-C5-methylases [Translation, ribosomal structure and biogenesis]; Region: Sun; COG0144
929556001557	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556001558	S-adenosylmethionine binding site [chemical binding]; other site
929556001559	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556001560	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556001561	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556001562	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556001563	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556001564	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556001565	TPR repeat; Region: TPR_11; pfam13414
929556001566	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556001567	binding surface
929556001568	TPR motif; other site
929556001569	nuc_hydro: Nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity.  This group contains eukaryotic, bacterial and archeal...; Region: nuc_hydro; cl00226
929556001570	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556001571	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
929556001572	Bleomycin binding protein (BLMA) and similar proteins; BLMA confers bleomycin (Bm) resistance by directly binding to Bm; Region: BLMA_like; cd08349
929556001573	dimer interface [polypeptide binding]; other site
929556001574	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556001575	ligand binding site [chemical binding]; other site
929556001576	hypothetical protein; Provisional; Region: PRK12378
929556001577	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
929556001578	amino acid transporter; Region: 2A0306; TIGR00909
929556001579	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
929556001580	H(+) -translocating inorganic pyrophosphatase; Region: PLN02255; cl11452
929556001581	membrane-bound proton-translocating pyrophosphatase; Validated; Region: hppA; PRK00733
929556001582	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
929556001583	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
929556001584	DNA-binding site [nucleotide binding]; DNA binding site
929556001585	RNA-binding motif; other site
929556001586	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
929556001587	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
929556001588	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
929556001589	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
929556001590	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
929556001591	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556001592	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556001593	binding surface
929556001594	TPR motif; other site
929556001595	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
929556001596	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556001597	binding surface
929556001598	TPR motif; other site
929556001599	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
929556001600	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556001601	binding surface
929556001602	TPR motif; other site
929556001603	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
929556001604	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
929556001605	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
929556001606	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
929556001607	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
929556001608	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929556001609	active site
929556001610	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
929556001611	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
929556001612	RNA binding site [nucleotide binding]; other site
929556001613	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
929556001614	RNA binding site [nucleotide binding]; other site
929556001615	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
929556001616	RNA binding site [nucleotide binding]; other site
929556001617	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
929556001618	RNA binding site [nucleotide binding]; other site
929556001619	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
929556001620	RNA binding site [nucleotide binding]; other site
929556001621	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
929556001622	cytidylate kinase; Provisional; Region: cmk; PRK00023
929556001623	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
929556001624	CMP-binding site; other site
929556001625	The sites determining sugar specificity; other site
929556001626	RDD family; Region: RDD; pfam06271
929556001627	hypothetical protein; Provisional; Region: PRK09256
929556001628	Protein of unknown function (DUF805); Region: DUF805; cl01224
929556001629	flagellar capping protein; Validated; Region: fliD; PRK08724
929556001630	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
929556001631	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
929556001632	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
929556001633	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
929556001634	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
929556001635	Lumazine binding domain; Region: Lum_binding; pfam00677
929556001636	Lumazine binding domain; Region: Lum_binding; pfam00677
929556001637	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
929556001638	Beta-lactamase; Region: Beta-lactamase; pfam00144
929556001639	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
929556001640	nudix motif; other site
929556001641	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556001642	Major Facilitator Superfamily; Region: MFS_1; pfam07690
929556001643	putative substrate translocation pore; other site
929556001644	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
929556001645	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556001646	Coenzyme A binding pocket [chemical binding]; other site
929556001647	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
929556001648	Predicted peptidase [General function prediction only]; Region: COG4099
929556001649	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556001650	Predicted integral membrane protein [Function unknown]; Region: COG3548
929556001651	chaperone protein HscA; Provisional; Region: hscA; PRK05183
929556001652	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
929556001653	nucleotide binding site [chemical binding]; other site
929556001654	putative NEF/HSP70 interaction site [polypeptide binding]; other site
929556001655	SBD interface [polypeptide binding]; other site
929556001656	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
929556001657	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
929556001658	dimer interface [polypeptide binding]; other site
929556001659	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556001660	catalytic residue [active]
929556001661	Glutamine cyclotransferase [Posttranslational modification, protein turnover, chaperones]; Region: COG3823
929556001662	dihydroorotase; Reviewed; Region: PRK09236
929556001663	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
929556001664	Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318
929556001665	active site
929556001666	helicase 45; Provisional; Region: PTZ00424
929556001667	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
929556001668	ATP binding site [chemical binding]; other site
929556001669	Mg++ binding site [ion binding]; other site
929556001670	motif III; other site
929556001671	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929556001672	nucleotide binding region [chemical binding]; other site
929556001673	ATP-binding site [chemical binding]; other site
929556001674	gliding motility-associated protein GldC; Region: GldC; TIGR03515
929556001675	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
929556001676	active site pocket [active]
929556001677	oxyanion hole [active]
929556001678	catalytic triad [active]
929556001679	active site nucleophile [active]
929556001680	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
929556001681	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556001682	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556001683	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
929556001684	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
929556001685	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
929556001686	tetramer interface [polypeptide binding]; other site
929556001687	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556001688	catalytic residue [active]
929556001689	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
929556001690	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
929556001691	substrate binding pocket [chemical binding]; other site
929556001692	Uncharacterized conserved protein [Function unknown]; Region: COG1284
929556001693	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
929556001694	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
929556001695	YCII-related domain; Region: YCII; cl00999
929556001696	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556001697	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556001698	ligand binding site [chemical binding]; other site
929556001699	flexible hinge region; other site
929556001700	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
929556001701	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
929556001702	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
929556001703	Found in ATP-dependent protease La (LON); Region: LON; smart00464
929556001704	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
929556001705	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556001706	Walker A motif; other site
929556001707	ATP binding site [chemical binding]; other site
929556001708	Walker B motif; other site
929556001709	arginine finger; other site
929556001710	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
929556001711	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
929556001712	Zn binding site [ion binding]; other site
929556001713	HupE / UreJ protein; Region: HupE_UreJ_2; pfam13795
929556001714	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
929556001715	glycerol kinase; Provisional; Region: glpK; PRK00047
929556001716	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
929556001717	N- and C-terminal domain interface [polypeptide binding]; other site
929556001718	active site
929556001719	MgATP binding site [chemical binding]; other site
929556001720	catalytic site [active]
929556001721	metal binding site [ion binding]; metal-binding site
929556001722	glycerol binding site [chemical binding]; other site
929556001723	homotetramer interface [polypeptide binding]; other site
929556001724	homodimer interface [polypeptide binding]; other site
929556001725	FBP binding site [chemical binding]; other site
929556001726	protein IIAGlc interface [polypeptide binding]; other site
929556001727	Protein of unknown function (DUF419); Region: DUF419; pfam04237
929556001728	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
929556001729	ribonucleoside--diphosphate reductase large subunit; Region: PLN02437
929556001730	ATP cone domain; Region: ATP-cone; pfam03477
929556001731	Class I ribonucleotide reductase; Region: RNR_I; cd01679
929556001732	active site
929556001733	dimer interface [polypeptide binding]; other site
929556001734	catalytic residues [active]
929556001735	effector binding site; other site
929556001736	R2 peptide binding site; other site
929556001737	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
929556001738	dimer interface [polypeptide binding]; other site
929556001739	putative radical transfer pathway; other site
929556001740	diiron center [ion binding]; other site
929556001741	tyrosyl radical; other site
929556001742	Response regulator receiver domain; Region: Response_reg; pfam00072
929556001743	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556001744	active site
929556001745	phosphorylation site [posttranslational modification]
929556001746	intermolecular recognition site; other site
929556001747	dimerization interface [polypeptide binding]; other site
929556001748	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cd01483
929556001749	ATP binding site [chemical binding]; other site
929556001750	substrate interface [chemical binding]; other site
929556001751	7TMR-DISM extracellular 2; Region: 7TMR-DISMED2; pfam07696
929556001752	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
929556001753	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556001754	dimer interface [polypeptide binding]; other site
929556001755	phosphorylation site [posttranslational modification]
929556001756	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556001757	ATP binding site [chemical binding]; other site
929556001758	Mg2+ binding site [ion binding]; other site
929556001759	G-X-G motif; other site
929556001760	Response regulator receiver domain; Region: Response_reg; pfam00072
929556001761	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556001762	active site
929556001763	phosphorylation site [posttranslational modification]
929556001764	intermolecular recognition site; other site
929556001765	dimerization interface [polypeptide binding]; other site
929556001766	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556001767	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556001768	dimer interface [polypeptide binding]; other site
929556001769	phosphorylation site [posttranslational modification]
929556001770	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556001771	ATP binding site [chemical binding]; other site
929556001772	Mg2+ binding site [ion binding]; other site
929556001773	G-X-G motif; other site
929556001774	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556001775	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
929556001776	active site
929556001777	phosphorylation site [posttranslational modification]
929556001778	intermolecular recognition site; other site
929556001779	dimerization interface [polypeptide binding]; other site
929556001780	Immunoglobulin domain; Region: Ig_2; pfam13895
929556001781	PKD domain; Region: PKD; pfam00801
929556001782	FOG: PKD repeat [General function prediction only]; Region: COG3291
929556001783	FOG: PKD repeat [General function prediction only]; Region: COG3291
929556001784	FOG: PKD repeat [General function prediction only]; Region: COG3291
929556001785	FOG: PKD repeat [General function prediction only]; Region: COG3291
929556001786	FOG: PKD repeat [General function prediction only]; Region: COG3291
929556001787	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
929556001788	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556001789	Putative glycoside hydrolase xylanase; Region: Xylanase; pfam13201
929556001790	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
929556001791	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
929556001792	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
929556001793	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
929556001794	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556001795	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
929556001796	?-D-glucose-1-phosphatase; Provisional; Region: PRK09456
929556001797	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
929556001798	Uncharacterized conserved protein [Function unknown]; Region: COG3379
929556001799	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; cl17415
929556001800	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
929556001801	intermolecular salt bridges; other site
929556001802	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
929556001803	Ligand Binding Site [chemical binding]; other site
929556001804	Ribosomal protein S4E [Translation, ribosomal structure and biogenesis]; Region: RPS4A; COG1471
929556001805	Methyltransferase domain; Region: Methyltransf_31; pfam13847
929556001806	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556001807	S-adenosylmethionine binding site [chemical binding]; other site
929556001808	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
929556001809	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
929556001810	PhnA protein; Region: PhnA; pfam03831
929556001811	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
929556001812	active site
929556001813	metal binding site [ion binding]; metal-binding site
929556001814	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556001815	YCII-related domain; Region: YCII; cl00999
929556001816	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
929556001817	human 17-beta-hydroxysteroid dehydrogenase XI-like, classical (c) SDRs; Region: 17beta-HSDXI-like_SDR_c; cd05339
929556001818	putative NAD(P) binding site [chemical binding]; other site
929556001819	homodimer interface [polypeptide binding]; other site
929556001820	active site
929556001821	substrate binding site [chemical binding]; other site
929556001822	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556001823	S-adenosylmethionine binding site [chemical binding]; other site
929556001824	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
929556001825	Two component regulator propeller; Region: Reg_prop; pfam07494
929556001826	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
929556001827	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556001828	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556001829	dimer interface [polypeptide binding]; other site
929556001830	phosphorylation site [posttranslational modification]
929556001831	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556001832	ATP binding site [chemical binding]; other site
929556001833	Mg2+ binding site [ion binding]; other site
929556001834	G-X-G motif; other site
929556001835	Response regulator receiver domain; Region: Response_reg; pfam00072
929556001836	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556001837	active site
929556001838	phosphorylation site [posttranslational modification]
929556001839	intermolecular recognition site; other site
929556001840	dimerization interface [polypeptide binding]; other site
929556001841	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
929556001842	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556001843	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556001844	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556001845	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556001846	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
929556001847	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556001848	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556001849	SusE outer membrane protein; Region: SusE; pfam14292
929556001850	carbohydrate-binding modules from Bacteroides thetaiotaomicron SusE, SusF and similar proteins; Region: CBM_SusE-F_like; cl17376
929556001851	starch binding site [chemical binding]; other site
929556001852	carbohydrate-binding modules from Bacteroides thetaiotaomicron SusE, SusF and similar proteins; Region: CBM_SusE-F_like; cl17376
929556001853	starch binding site [chemical binding]; other site
929556001854	Glycosyl hydrolase family 66; Region: Glyco_hydro_66; pfam13199
929556001855	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
929556001856	Carbohydrate Binding Module 6 (CBM6) domains; many are found in association with discoidin domain(s); Region: CBM6_discoidin-like; cd04083
929556001857	DinB superfamily; Region: DinB_2; pfam12867
929556001858	alkylhydroperoxidase AhpD family core domain; Region: ahpD_dom; TIGR00778
929556001859	Uncharacterized conserved protein [Function unknown]; Region: COG2128
929556001860	YCII-related domain; Region: YCII; cl00999
929556001861	Predicted RNA polymerase sigma factor containing a TPR repeat domain [Transcription]; Region: COG4941
929556001862	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556001863	Uncharacterized proteins similar to Bacteroides ovatus 4320; Region: Bacova_04320_like; cd12190
929556001864	Uncharacterized proteins similar to Bacteroides ovatus 4320; Region: Bacova_04320_like; cd12190
929556001865	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
929556001866	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556001867	Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030
929556001868	Nodulation formation efficiency D (NfeD) is a membrane-bound ClpP-class protease; Region: Clp_protease_NfeD_1; cd07020
929556001869	dimer interface [polypeptide binding]; other site
929556001870	active site residues [active]
929556001871	NfeD-like C-terminal, partner-binding; Region: NfeD; pfam01957
929556001872	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
929556001873	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
929556001874	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
929556001875	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
929556001876	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
929556001877	acyl-activating enzyme (AAE) consensus motif; other site
929556001878	acyl-activating enzyme (AAE) consensus motif; other site
929556001879	putative AMP binding site [chemical binding]; other site
929556001880	putative active site [active]
929556001881	putative CoA binding site [chemical binding]; other site
929556001882	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
929556001883	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
929556001884	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
929556001885	trimerization site [polypeptide binding]; other site
929556001886	active site
929556001887	cysteine desulfurase; Provisional; Region: PRK14012
929556001888	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
929556001889	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929556001890	catalytic residue [active]
929556001891	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556001892	Methylmalonyl-CoA epimerase (MMCE); Region: MMCE; cd07249
929556001893	dimer interface [polypeptide binding]; other site
929556001894	substrate binding site [chemical binding]; other site
929556001895	metal binding site [ion binding]; metal-binding site
929556001896	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556001897	Coenzyme A binding pocket [chemical binding]; other site
929556001898	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
929556001899	Transposase; Region: HTH_Tnp_1; cl17663
929556001900	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
929556001901	putative transposase OrfB; Reviewed; Region: PHA02517
929556001902	Integrase core domain; Region: rve; pfam00665
929556001903	Integrase core domain; Region: rve_3; cl15866
929556001904	UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Region: alt_bact_glmU; TIGR03991
929556001905	Sugar nucleotidyl transferase; Region: NTP_transf_4; pfam13562
929556001906	Uncharacterized proteins, Left-handed parallel beta-Helix (LbH) domain: Members in this group are uncharacterized bacterial proteins containing a LbH domain with multiple turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif...; Region: LbH_unknown; cd05635
929556001907	triosephosphate isomerase; Provisional; Region: PRK14567
929556001908	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
929556001909	substrate binding site [chemical binding]; other site
929556001910	dimer interface [polypeptide binding]; other site
929556001911	catalytic triad [active]
929556001912	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
929556001913	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556001914	S-adenosylmethionine binding site [chemical binding]; other site
929556001915	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
929556001916	Coenzyme A binding pocket [chemical binding]; other site
929556001917	YoaP-like; Region: YoaP; pfam14268
929556001918	UDP-N-acetylmuramate-alanine ligase [Cell envelope biogenesis, outer membrane]; Region: MurC; COG0773
929556001919	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
929556001920	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
929556001921	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
929556001922	GxxExxY protein; Region: GxxExxY; TIGR04256
929556001923	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
929556001924	active site
929556001925	metal binding site [ion binding]; metal-binding site
929556001926	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
929556001927	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
929556001928	RNA 2'-phosphotransferase, Tpt1 / KptA family; Region: PTS_2-RNA; pfam01885
929556001929	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
929556001930	putative ADP-ribose binding site [chemical binding]; other site
929556001931	putative active site [active]
929556001932	Domain of unknown function (DUF1768); Region: DUF1768; pfam08719
929556001933	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
929556001934	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
929556001935	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
929556001936	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
929556001937	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
929556001938	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
929556001939	putative hydrolase; Provisional; Region: PRK02113
929556001940	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
929556001941	Uncharacterized proteins similar to Bacteroides ovatus 4320; Region: Bacova_04320_like; cd12190
929556001942	Cupin domain; Region: Cupin_2; cl17218
929556001943	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
929556001944	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
929556001945	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
929556001946	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556001947	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
929556001948	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929556001949	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929556001950	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929556001951	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929556001952	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929556001953	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929556001954	Low molecular weight phosphatase family; Region: LMWPc; cl00105
929556001955	active site
929556001956	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
929556001957	homotrimer interaction site [polypeptide binding]; other site
929556001958	putative active site [active]
929556001959	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
929556001960	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
929556001961	active site
929556001962	(T/H)XGH motif; other site
929556001963	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
929556001964	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556001965	S-adenosylmethionine binding site [chemical binding]; other site
929556001966	Protein of unknown function (DUF3822); Region: DUF3822; pfam12864
929556001967	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556001968	AAA domain; Region: AAA_22; pfam13401
929556001969	Walker A motif; other site
929556001970	ATP binding site [chemical binding]; other site
929556001971	Walker B motif; other site
929556001972	Family description; Region: UvrD_C_2; pfam13538
929556001973	Type 1 glutamine amidotransferase (GATase1)-like domain found in cyanophycinase; Region: GAT1_cyanophycinase; cd03145
929556001974	proposed catalytic triad [active]
929556001975	active site nucleophile [active]
929556001976	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
929556001977	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
929556001978	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
929556001979	active site
929556001980	Fn3 associated; Region: Fn3_assoc; pfam13287
929556001981	DNA polymerase IV; Reviewed; Region: PRK03103
929556001982	Y-family of DNA polymerases; Region: PolY; cd00424
929556001983	active site
929556001984	DNA binding site [nucleotide binding]
929556001985	Protein of unknown function (DUF4230); Region: DUF4230; pfam14014
929556001986	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
929556001987	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
929556001988	active site
929556001989	DNA binding site [nucleotide binding]
929556001990	Int/Topo IB signature motif; other site
929556001991	Uncharacterized proteins similar to Bacteroides ovatus 4320; Region: Bacova_04320_like; cd12190
929556001992	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
929556001993	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
929556001994	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
929556001995	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
929556001996	tandem repeat interface [polypeptide binding]; other site
929556001997	oligomer interface [polypeptide binding]; other site
929556001998	active site residues [active]
929556001999	Protein of unknown function (DUF4238); Region: DUF4238; pfam14022
929556002000	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
929556002001	HNH endonuclease; Region: HNH_3; pfam13392
929556002002	AAA domain; Region: AAA_17; pfam13207
929556002003	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; cl17639
929556002004	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
929556002005	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
929556002006	DNA binding residues [nucleotide binding]
929556002007	dimerization interface [polypeptide binding]; other site
929556002008	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
929556002009	non-specific DNA binding site [nucleotide binding]; other site
929556002010	salt bridge; other site
929556002011	sequence-specific DNA binding site [nucleotide binding]; other site
929556002012	M28 Zn-Peptidases containing a PA domain insert and associated with a PDZ domain; Region: M28_like_PA_PDZ_associated; cd05663
929556002013	Peptidase family M28; Region: Peptidase_M28; pfam04389
929556002014	metal binding site [ion binding]; metal-binding site
929556002015	Protein of unknown function (DUF2891); Region: DUF2891; pfam11199
929556002016	CsbD-like; Region: CsbD; pfam05532
929556002017	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
929556002018	active site
929556002019	Ap6A binding site [chemical binding]; other site
929556002020	nudix motif; other site
929556002021	metal binding site [ion binding]; metal-binding site
929556002022	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929556002023	active site
929556002024	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
929556002025	Clp amino terminal domain; Region: Clp_N; pfam02861
929556002026	Clp amino terminal domain; Region: Clp_N; pfam02861
929556002027	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556002028	Walker A motif; other site
929556002029	ATP binding site [chemical binding]; other site
929556002030	Walker B motif; other site
929556002031	arginine finger; other site
929556002032	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556002033	Walker A motif; other site
929556002034	ATP binding site [chemical binding]; other site
929556002035	Walker B motif; other site
929556002036	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
929556002037	CcmB protein; Region: CcmB; cl17444
929556002038	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
929556002039	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
929556002040	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
929556002041	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
929556002042	NAD(P) binding site [chemical binding]; other site
929556002043	Dodecin; Region: Dodecin; pfam07311
929556002044	CcmE; Region: CcmE; cl00994
929556002045	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: CcmF; COG1138
929556002046	Rossmann-like domain; Region: Rossmann-like; pfam10727
929556002047	Domain of unknown function (DUF2520); Region: DUF2520; pfam10728
929556002048	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
929556002049	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
929556002050	catalytic loop [active]
929556002051	iron binding site [ion binding]; other site
929556002052	Iron-sulphur cluster assembly; Region: Fe-S_assembly; pfam04384
929556002053	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929556002054	active site
929556002055	motif I; other site
929556002056	motif II; other site
929556002057	Maf-like protein; Region: Maf; pfam02545
929556002058	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
929556002059	active site
929556002060	dimer interface [polypeptide binding]; other site
929556002061	exopolyphosphatase; Region: exo_poly_only; TIGR03706
929556002062	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
929556002063	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
929556002064	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
929556002065	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
929556002066	ATP-binding cassette domain of an uncharacterized transporter; Region: ABC_putative_ATPase; cd03269
929556002067	Walker A/P-loop; other site
929556002068	ATP binding site [chemical binding]; other site
929556002069	Q-loop/lid; other site
929556002070	ABC transporter signature motif; other site
929556002071	Walker B; other site
929556002072	D-loop; other site
929556002073	H-loop/switch region; other site
929556002074	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
929556002075	Acyltransferase family; Region: Acyl_transf_3; pfam01757
929556002076	chaperone protein DnaJ; Provisional; Region: PRK14289
929556002077	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
929556002078	HSP70 interaction site [polypeptide binding]; other site
929556002079	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
929556002080	substrate binding site [polypeptide binding]; other site
929556002081	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
929556002082	Zn binding sites [ion binding]; other site
929556002083	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
929556002084	dimer interface [polypeptide binding]; other site
929556002085	GrpE; Region: GrpE; pfam01025
929556002086	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
929556002087	dimer interface [polypeptide binding]; other site
929556002088	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
929556002089	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
929556002090	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556002091	Walker A/P-loop; other site
929556002092	ATP binding site [chemical binding]; other site
929556002093	Q-loop/lid; other site
929556002094	ABC transporter signature motif; other site
929556002095	Walker B; other site
929556002096	D-loop; other site
929556002097	H-loop/switch region; other site
929556002098	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
929556002099	NAD(P) binding site [chemical binding]; other site
929556002100	4Fe-4S binding domain; Region: Fer4; pfam00037
929556002101	Bacterial SH3 domain; Region: SH3_3; pfam08239
929556002102	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
929556002103	NlpC/P60 family; Region: NLPC_P60; pfam00877
929556002104	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
929556002105	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
929556002106	active site
929556002107	Putative carbohydrate binding domain; Region: CHB_HEX; cl03918
929556002108	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
929556002109	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
929556002110	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
929556002111	active site
929556002112	C-terminal Early set domain associated with the catalytic domain of chitobiase (also called N-acetylglucosaminidase); Region: E_set_Chitobiase_C; cd02847
929556002113	FOG: WD40 repeat [General function prediction only]; Region: COG2319
929556002114	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
929556002115	structural tetrad; other site
929556002116	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
929556002117	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
929556002118	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
929556002119	metal binding site [ion binding]; metal-binding site
929556002120	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
929556002121	putative active site [active]
929556002122	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
929556002123	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
929556002124	substrate binding site [chemical binding]; other site
929556002125	glutamase interaction surface [polypeptide binding]; other site
929556002126	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
929556002127	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
929556002128	catalytic residues [active]
929556002129	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13181
929556002130	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
929556002131	putative active site [active]
929556002132	oxyanion strand; other site
929556002133	catalytic triad [active]
929556002134	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
929556002135	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929556002136	active site
929556002137	motif I; other site
929556002138	motif II; other site
929556002139	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
929556002140	putative active site pocket [active]
929556002141	4-fold oligomerization interface [polypeptide binding]; other site
929556002142	metal binding residues [ion binding]; metal-binding site
929556002143	3-fold/trimer interface [polypeptide binding]; other site
929556002144	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
929556002145	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
929556002146	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556002147	homodimer interface [polypeptide binding]; other site
929556002148	catalytic residue [active]
929556002149	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
929556002150	histidinol dehydrogenase; Region: hisD; TIGR00069
929556002151	NAD binding site [chemical binding]; other site
929556002152	dimerization interface [polypeptide binding]; other site
929556002153	product binding site; other site
929556002154	substrate binding site [chemical binding]; other site
929556002155	zinc binding site [ion binding]; other site
929556002156	catalytic residues [active]
929556002157	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
929556002158	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
929556002159	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cd00368
929556002160	molybdopterin cofactor binding site; other site
929556002161	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
929556002162	Aerotolerance regulator N-terminal; Region: BatA; pfam07584
929556002163	CARDB; Region: CARDB; pfam07705
929556002164	dihydroorotase; Validated; Region: pyrC; PRK09357
929556002165	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
929556002166	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
929556002167	active site
929556002168	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
929556002169	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
929556002170	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
929556002171	Ligand binding site; other site
929556002172	Putative Catalytic site; other site
929556002173	DXD motif; other site
929556002174	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
929556002175	This family is most closely related to the GT1 family of glycosyltransferases. ORF704 in E. coli has been shown to be involved in the biosynthesis of O-specific mannose homopolysaccharides; Region: GT1_ecORF704_like; cd03822
929556002176	TraB family; Region: TraB; pfam01963
929556002177	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
929556002178	GH3 auxin-responsive promoter; Region: GH3; pfam03321
929556002179	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
929556002180	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
929556002181	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
929556002182	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
929556002183	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
929556002184	RIP metalloprotease RseP; Region: TIGR00054
929556002185	active site
929556002186	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
929556002187	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
929556002188	putative substrate binding region [chemical binding]; other site
929556002189	DnaJ domain; Region: DnaJ; pfam00226
929556002190	HSP70 interaction site [polypeptide binding]; other site
929556002191	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
929556002192	Acyltransferase family; Region: Acyl_transf_3; pfam01757
929556002193	YceI-like domain; Region: YceI; pfam04264
929556002194	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
929556002195	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556002196	ligand binding site [chemical binding]; other site
929556002197	DinB superfamily; Region: DinB_2; pfam12867
929556002198	Protein of unknown function DUF2625; Region: DUF2625; pfam10946
929556002199	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
929556002200	Beta-lactamase; Region: Beta-lactamase; pfam00144
929556002201	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
929556002202	Tetratricopeptide repeat; Region: TPR_16; pfam13432
929556002203	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556002204	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
929556002205	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556002206	ligand binding site [chemical binding]; other site
929556002207	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
929556002208	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556002209	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556002210	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556002211	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556002212	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556002213	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
929556002214	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
929556002215	active site
929556002216	metal binding site [ion binding]; metal-binding site
929556002217	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
929556002218	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
929556002219	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
929556002220	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929556002221	non-specific DNA binding site [nucleotide binding]; other site
929556002222	salt bridge; other site
929556002223	sequence-specific DNA binding site [nucleotide binding]; other site
929556002224	Cupin domain; Region: Cupin_2; pfam07883
929556002225	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
929556002226	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556002227	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556002228	DNA binding residues [nucleotide binding]
929556002229	FecR protein; Region: FecR; pfam04773
929556002230	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
929556002231	Secretin and TonB N terminus short domain; Region: STN; pfam07660
929556002232	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556002233	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556002234	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
929556002235	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556002236	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556002237	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
929556002238	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
929556002239	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556002240	catalytic residues [active]
929556002241	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
929556002242	Transposase, Mutator family; Region: Transposase_mut; pfam00872
929556002243	MULE transposase domain; Region: MULE; pfam10551
929556002244	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
929556002245	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
929556002246	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
929556002247	active site
929556002248	Fn3 associated; Region: Fn3_assoc; pfam13287
929556002249	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
929556002250	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
929556002251	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
929556002252	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to regulators involved in the catabolism of aromatic compounds, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like_2; cd08448
929556002253	putative dimerization interface [polypeptide binding]; other site
929556002254	putative substrate binding pocket [chemical binding]; other site
929556002255	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
929556002256	Domain of unknown function (DUF1338); Region: DUF1338; pfam07063
929556002257	aldehyde dehydrogenase family 7 member; Region: PLN02315
929556002258	NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B; Region: ALDH_F7_AASADH; cd07130
929556002259	tetrameric interface [polypeptide binding]; other site
929556002260	NAD binding site [chemical binding]; other site
929556002261	catalytic residues [active]
929556002262	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
929556002263	FAD binding domain; Region: FAD_binding_4; pfam01565
929556002264	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
929556002265	sn-glycerol-3-phosphate dehydrogenase subunit C; Provisional; Region: glpC; PRK11168
929556002266	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
929556002267	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556002268	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556002269	DNA binding residues [nucleotide binding]
929556002270	FecR protein; Region: FecR; pfam04773
929556002271	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
929556002272	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556002273	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556002274	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
929556002275	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556002276	catalytic residues [active]
929556002277	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
929556002278	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
929556002279	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
929556002280	protein binding site [polypeptide binding]; other site
929556002281	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
929556002282	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929556002283	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929556002284	ABC transporter; Region: ABC_tran_2; pfam12848
929556002285	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929556002286	Cytochrome c; Region: Cytochrom_C; pfam00034
929556002287	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
929556002288	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
929556002289	Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625
929556002290	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556002291	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556002292	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
929556002293	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556002294	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556002295	DNA binding residues [nucleotide binding]
929556002296	RHS Repeat; Region: RHS_repeat; cl11982
929556002297	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
929556002298	Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_4; cd08897
929556002299	putative hydrophobic ligand binding site [chemical binding]; other site
929556002300	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
929556002301	Conserved hypothetical phage protein (DUF2376); Region: DUF2376; cl09774
929556002302	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
929556002303	putative DNA binding site [nucleotide binding]; other site
929556002304	dimerization interface [polypeptide binding]; other site
929556002305	putative Zn2+ binding site [ion binding]; other site
929556002306	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
929556002307	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
929556002308	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556002309	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
929556002310	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
929556002311	Transcriptional regulators [Transcription]; Region: MarR; COG1846
929556002312	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
929556002313	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556002314	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556002315	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556002316	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
929556002317	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556002318	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556002319	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
929556002320	ligand binding site [chemical binding]; other site
929556002321	EthD domain; Region: EthD; cl17553
929556002322	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556002323	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556002324	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556002325	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556002326	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
929556002327	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556002328	Protein of unknown function (DUF1343); Region: DUF1343; pfam07075
929556002329	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556002330	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556002331	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556002332	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
929556002333	starch binding outer membrane protein SusD; Region: SusD; cl17845
929556002334	starch binding outer membrane protein SusD; Region: SusD; cl17845
929556002335	Protein of unknown function (DUF1343); Region: DUF1343; pfam07075
929556002336	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556002337	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556002338	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556002339	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
929556002340	starch binding outer membrane protein SusD; Region: SusD; cl17845
929556002341	SusD family; Region: SusD; pfam07980
929556002342	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
929556002343	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
929556002344	active site
929556002345	metal binding site [ion binding]; metal-binding site
929556002346	PQQ-like domain; Region: PQQ_2; pfam13360
929556002347	YWTD domain; Region: YWTD; cl17223
929556002348	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
929556002349	Trp docking motif [polypeptide binding]; other site
929556002350	active site
929556002351	PQQ-like domain; Region: PQQ_2; pfam13360
929556002352	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
929556002353	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
929556002354	Beta-lactamase; Region: Beta-lactamase; cl17358
929556002355	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
929556002356	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
929556002357	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
929556002358	putative active site [active]
929556002359	Na(+)/iodide (NIS) and Na(+)/multivitamin (SMVT) cotransporters, and related proteins; solute binding domain; Region: SLC5sbd_NIS-like; cd10326
929556002360	Na binding site [ion binding]; other site
929556002361	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
929556002362	FAD binding domain; Region: FAD_binding_4; pfam01565
929556002363	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
929556002364	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
929556002365	A new structural DNA glycosylase; Region: AlkD_like; cd06561
929556002366	active site
929556002367	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
929556002368	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
929556002369	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
929556002370	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
929556002371	Aspartase; Region: Aspartase; cd01357
929556002372	active sites [active]
929556002373	tetramer interface [polypeptide binding]; other site
929556002374	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556002375	ligand binding site [chemical binding]; other site
929556002376	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
929556002377	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
929556002378	Response regulator receiver domain; Region: Response_reg; pfam00072
929556002379	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556002380	active site
929556002381	phosphorylation site [posttranslational modification]
929556002382	intermolecular recognition site; other site
929556002383	dimerization interface [polypeptide binding]; other site
929556002384	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556002385	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556002386	ligand binding site [chemical binding]; other site
929556002387	flexible hinge region; other site
929556002388	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
929556002389	putative switch regulator; other site
929556002390	non-specific DNA interactions [nucleotide binding]; other site
929556002391	DNA binding site [nucleotide binding]
929556002392	sequence specific DNA binding site [nucleotide binding]; other site
929556002393	putative cAMP binding site [chemical binding]; other site
929556002394	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Region: Caa3_CtaG; cl09173
929556002395	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
929556002396	Sulfatase; Region: Sulfatase; pfam00884
929556002397	PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_5; cd03394
929556002398	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
929556002399	active site
929556002400	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556002401	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
929556002402	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
929556002403	N-terminal plug; other site
929556002404	ligand-binding site [chemical binding]; other site
929556002405	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
929556002406	dimer interface [polypeptide binding]; other site
929556002407	phosphorylation site [posttranslational modification]
929556002408	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556002409	ATP binding site [chemical binding]; other site
929556002410	Mg2+ binding site [ion binding]; other site
929556002411	G-X-G motif; other site
929556002412	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929556002413	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556002414	active site
929556002415	phosphorylation site [posttranslational modification]
929556002416	intermolecular recognition site; other site
929556002417	dimerization interface [polypeptide binding]; other site
929556002418	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929556002419	DNA binding site [nucleotide binding]
929556002420	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
929556002421	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
929556002422	FAD binding pocket [chemical binding]; other site
929556002423	FAD binding motif [chemical binding]; other site
929556002424	phosphate binding motif [ion binding]; other site
929556002425	beta-alpha-beta structure motif; other site
929556002426	NAD(p) ribose binding residues [chemical binding]; other site
929556002427	NAD binding pocket [chemical binding]; other site
929556002428	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
929556002429	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
929556002430	catalytic loop [active]
929556002431	iron binding site [ion binding]; other site
929556002432	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
929556002433	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
929556002434	putative active site [active]
929556002435	putative metal binding site [ion binding]; other site
929556002436	helicase 45; Provisional; Region: PTZ00424
929556002437	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
929556002438	ATP binding site [chemical binding]; other site
929556002439	putative Mg++ binding site [ion binding]; other site
929556002440	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
929556002441	nucleotide binding region [chemical binding]; other site
929556002442	ATP-binding site [chemical binding]; other site
929556002443	Trehalase; Region: Trehalase; cl17346
929556002444	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
929556002445	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
929556002446	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
929556002447	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
929556002448	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
929556002449	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
929556002450	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
929556002451	Carbohydrate Binding Module Family 6 (CBM6), Fibrobacter succinogenes S85 Xyn10D-like; appended mainly to glycoside hydrolase (GH) family 5 and GH43 domains; Region: CBM6_FsXyn10D-like; cd09838
929556002452	putative metal binding site [ion binding]; other site
929556002453	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
929556002454	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
929556002455	Family of unknown function (DUF490); Region: DUF490; pfam04357
929556002456	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
929556002457	Surface antigen; Region: Bac_surface_Ag; pfam01103
929556002458	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
929556002459	Permease; Region: Permease; pfam02405
929556002460	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
929556002461	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
929556002462	Walker A/P-loop; other site
929556002463	ATP binding site [chemical binding]; other site
929556002464	Q-loop/lid; other site
929556002465	ABC transporter signature motif; other site
929556002466	Walker B; other site
929556002467	D-loop; other site
929556002468	H-loop/switch region; other site
929556002469	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
929556002470	mce related protein; Region: MCE; pfam02470
929556002471	Protein of unknown function (DUF1469); Region: DUF1469; pfam07332
929556002472	putative exonuclease, DNA ligase-associated; Region: Xnuc_lig_assoc; TIGR04122
929556002473	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
929556002474	ATP-dependent DNA ligase; Validated; Region: PRK09247
929556002475	Adenylation domain of putative bacterial ATP-dependent DNA ligases; Region: Adenylation_DNA_ligase_Bac1; cd07897
929556002476	active site
929556002477	DNA binding site [nucleotide binding]
929556002478	The Oligonucleotide/oligosaccharide binding (OB)-fold domain of archaeal and bacterial ATP-dependent DNA ligases is a DNA-binding module that is part of the catalytic core unit; Region: OBF_DNA_ligase_Arch_LigB; cd07972
929556002479	DNA binding site [nucleotide binding]
929556002480	DEXH box helicase, DNA ligase-associated; Region: DEXH_lig_assoc; TIGR04121
929556002481	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929556002482	ATP binding site [chemical binding]; other site
929556002483	putative Mg++ binding site [ion binding]; other site
929556002484	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929556002485	nucleotide binding region [chemical binding]; other site
929556002486	ATP-binding site [chemical binding]; other site
929556002487	DEAD/H associated; Region: DEAD_assoc; pfam08494
929556002488	Pyrococcus furiosus PF1019 and related proteins, metallophosphatase domain; Region: MPP_PF1019; cd07391
929556002489	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
929556002490	putative active site [active]
929556002491	putative metal binding site [ion binding]; other site
929556002492	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
929556002493	This family is most closely related to the GT1 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant...; Region: GT1_AviGT4_like; cd03802
929556002494	putative ADP-binding pocket [chemical binding]; other site
929556002495	Glycogen debranching enzyme [Carbohydrate transport and metabolism]; Region: GDB1; COG3408
929556002496	Amylo-alpha-1,6-glucosidase; Region: GDE_C; pfam06202
929556002497	Domain of unknown function (DUF2383); Region: DUF2383; cl17556
929556002498	H+ Antiporter protein; Region: 2A0121; TIGR00900
929556002499	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556002500	putative substrate translocation pore; other site
929556002501	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
929556002502	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
929556002503	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
929556002504	dimerization interface [polypeptide binding]; other site
929556002505	Transcriptional regulators [Transcription]; Region: PurR; COG1609
929556002506	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
929556002507	DNA binding site [nucleotide binding]
929556002508	domain linker motif; other site
929556002509	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
929556002510	dimerization interface [polypeptide binding]; other site
929556002511	ligand binding site [chemical binding]; other site
929556002512	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556002513	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556002514	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556002515	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
929556002516	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556002517	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
929556002518	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
929556002519	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
929556002520	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556002521	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
929556002522	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556002523	binding surface
929556002524	TPR motif; other site
929556002525	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
929556002526	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556002527	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
929556002528	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556002529	ligand binding site [chemical binding]; other site
929556002530	Helix-turn-helix domain; Region: HTH_20; pfam12840
929556002531	Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416
929556002532	RNA polymerase sigma factor SigW; Provisional; Region: PRK09641
929556002533	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556002534	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556002535	DNA binding residues [nucleotide binding]
929556002536	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
929556002537	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
929556002538	Uncharacterized conserved protein, YhbC family [Function unknown]; Region: COG0782
929556002539	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929556002540	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
929556002541	NAD(P) binding site [chemical binding]; other site
929556002542	active site
929556002543	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
929556002544	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556002545	Walker A/P-loop; other site
929556002546	ATP binding site [chemical binding]; other site
929556002547	Q-loop/lid; other site
929556002548	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556002549	ABC transporter signature motif; other site
929556002550	Walker B; other site
929556002551	D-loop; other site
929556002552	H-loop/switch region; other site
929556002553	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
929556002554	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
929556002555	active site
929556002556	metal binding site [ion binding]; metal-binding site
929556002557	DNA binding site [nucleotide binding]
929556002558	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
929556002559	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
929556002560	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
929556002561	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556002562	catalytic residues [active]
929556002563	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
929556002564	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
929556002565	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556002566	catalytic residues [active]
929556002567	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
929556002568	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
929556002569	[2Fe-2S] cluster binding site [ion binding]; other site
929556002570	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
929556002571	hydrophobic ligand binding site; other site
929556002572	arginine:agmatin antiporter; Provisional; Region: PRK10644
929556002573	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
929556002574	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
929556002575	intersubunit interface [polypeptide binding]; other site
929556002576	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
929556002577	Transposase; Region: DDE_Tnp_ISL3; pfam01610
929556002578	Short C-terminal domain; Region: SHOCT; pfam09851
929556002579	AAA domain; Region: AAA_21; pfam13304
929556002580	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556002581	ABC transporter signature motif; other site
929556002582	Walker B; other site
929556002583	D-loop; other site
929556002584	H-loop/switch region; other site
929556002585	Glutamine cyclotransferase [Posttranslational modification, protein turnover, chaperones]; Region: COG3823
929556002586	NIPSNAP; Region: NIPSNAP; pfam07978
929556002587	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
929556002588	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
929556002589	dimer interface [polypeptide binding]; other site
929556002590	ADP-ribose binding site [chemical binding]; other site
929556002591	active site
929556002592	nudix motif; other site
929556002593	metal binding site [ion binding]; metal-binding site
929556002594	DinB superfamily; Region: DinB_2; pfam12867
929556002595	trigger factor; Region: tig; TIGR00115
929556002596	Clp protease; Region: CLP_protease; pfam00574
929556002597	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
929556002598	oligomer interface [polypeptide binding]; other site
929556002599	active site residues [active]
929556002600	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
929556002601	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
929556002602	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556002603	Walker A motif; other site
929556002604	ATP binding site [chemical binding]; other site
929556002605	Walker B motif; other site
929556002606	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
929556002607	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556002608	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
929556002609	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
929556002610	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556002611	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
929556002612	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556002613	ligand binding site [chemical binding]; other site
929556002614	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
929556002615	Glycogen synthase; Region: Glycogen_syn; pfam05693
929556002616	cystathionine beta-synthase; Region: cysta_beta; TIGR01137
929556002617	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
929556002618	dimer interface [polypeptide binding]; other site
929556002619	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556002620	catalytic residue [active]
929556002621	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the pyridoxal-phosphate (PALP) dependent enzyme domain upstream.   The vitamin B6 complex comprises pyridoxine, pyridoxal, and pyridoxamine, as well...; Region: CBS_pair_PALP_assoc2; cd04609
929556002622	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
929556002623	propionate/acetate kinase; Provisional; Region: PRK12379
929556002624	phosphate acetyltransferase; Reviewed; Region: PRK05632
929556002625	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
929556002626	DRTGG domain; Region: DRTGG; pfam07085
929556002627	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
929556002628	Peptidase C1-like family; Region: Peptidase_C1_2; cl17447
929556002629	LysE type translocator; Region: LysE; cl00565
929556002630	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
929556002631	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
929556002632	hinge; other site
929556002633	active site
929556002634	Domain of unknown function (DUF4290); Region: DUF4290; pfam14123
929556002635	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
929556002636	Part of AAA domain; Region: AAA_19; pfam13245
929556002637	Family description; Region: UvrD_C_2; pfam13538
929556002638	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
929556002639	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556002640	ligand binding site [chemical binding]; other site
929556002641	hypothetical protein; Provisional; Region: PRK08201
929556002642	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_3; cd05680
929556002643	metal binding site [ion binding]; metal-binding site
929556002644	putative dimer interface [polypeptide binding]; other site
929556002645	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
929556002646	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556002647	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556002648	DNA binding residues [nucleotide binding]
929556002649	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
929556002650	FecR protein; Region: FecR; pfam04773
929556002651	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556002652	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556002653	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556002654	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556002655	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556002656	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556002657	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
929556002658	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
929556002659	active site
929556002660	catalytic site [active]
929556002661	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
929556002662	active site
929556002663	catalytic residues [active]
929556002664	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
929556002665	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
929556002666	active site
929556002667	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
929556002668	Surface antigen; Region: Bac_surface_Ag; pfam01103
929556002669	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
929556002670	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
929556002671	active site
929556002672	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
929556002673	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
929556002674	active site
929556002675	catalytic tetrad [active]
929556002676	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
929556002677	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
929556002678	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
929556002679	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
929556002680	active site
929556002681	metal binding site [ion binding]; metal-binding site
929556002682	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
929556002683	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
929556002684	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
929556002685	hexamer interface [polypeptide binding]; other site
929556002686	ligand binding site [chemical binding]; other site
929556002687	putative active site [active]
929556002688	NAD(P) binding site [chemical binding]; other site
929556002689	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556002690	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556002691	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
929556002692	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
929556002693	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556002694	active site
929556002695	phosphorylation site [posttranslational modification]
929556002696	intermolecular recognition site; other site
929556002697	dimerization interface [polypeptide binding]; other site
929556002698	LytTr DNA-binding domain; Region: LytTR; pfam04397
929556002699	Histidine kinase; Region: His_kinase; pfam06580
929556002700	Domain of unknown function (DUF4288); Region: DUF4288; pfam14119
929556002701	Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922
929556002702	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
929556002703	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
929556002704	catalytic residues [active]
929556002705	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
929556002706	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
929556002707	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
929556002708	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
929556002709	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
929556002710	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
929556002711	N-terminal plug; other site
929556002712	ligand-binding site [chemical binding]; other site
929556002713	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
929556002714	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
929556002715	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556002716	Coenzyme A binding pocket [chemical binding]; other site
929556002717	recombination factor protein RarA; Reviewed; Region: PRK13342
929556002718	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556002719	Walker A motif; other site
929556002720	ATP binding site [chemical binding]; other site
929556002721	Walker B motif; other site
929556002722	arginine finger; other site
929556002723	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
929556002724	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
929556002725	C1q domain; Region: C1q; cl17543
929556002726	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
929556002727	DNA topoisomerase I; Provisional; Region: PRK08780
929556002728	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
929556002729	active site
929556002730	interdomain interaction site; other site
929556002731	putative metal-binding site [ion binding]; other site
929556002732	nucleotide binding site [chemical binding]; other site
929556002733	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
929556002734	domain I; other site
929556002735	DNA binding groove [nucleotide binding]
929556002736	phosphate binding site [ion binding]; other site
929556002737	domain II; other site
929556002738	domain III; other site
929556002739	nucleotide binding site [chemical binding]; other site
929556002740	catalytic site [active]
929556002741	domain IV; other site
929556002742	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
929556002743	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
929556002744	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
929556002745	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
929556002746	MG2 domain; Region: A2M_N; pfam01835
929556002747	Alpha-2-macroglobulin family; Region: A2M; pfam00207
929556002748	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
929556002749	surface patch; other site
929556002750	thioester region; other site
929556002751	specificity defining residues; other site
929556002752	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
929556002753	penicillin-binding protein 1C; Region: PBP_1c; TIGR02073
929556002754	Transglycosylase; Region: Transgly; pfam00912
929556002755	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
929556002756	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
929556002757	Peptidase family M48; Region: Peptidase_M48; cl12018
929556002758	Protein of unknown function (DUF4011); Region: DUF4011; pfam13195
929556002759	Part of AAA domain; Region: AAA_19; pfam13245
929556002760	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
929556002761	AAA domain; Region: AAA_12; pfam13087
929556002762	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
929556002763	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
929556002764	active site
929556002765	catalytic site [active]
929556002766	substrate binding site [chemical binding]; other site
929556002767	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
929556002768	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
929556002769	Walker A/P-loop; other site
929556002770	ATP binding site [chemical binding]; other site
929556002771	Q-loop/lid; other site
929556002772	ABC transporter signature motif; other site
929556002773	Walker B; other site
929556002774	D-loop; other site
929556002775	H-loop/switch region; other site
929556002776	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
929556002777	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
929556002778	Walker A/P-loop; other site
929556002779	ATP binding site [chemical binding]; other site
929556002780	Q-loop/lid; other site
929556002781	ABC transporter signature motif; other site
929556002782	Walker B; other site
929556002783	D-loop; other site
929556002784	H-loop/switch region; other site
929556002785	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
929556002786	Bacterial protein of unknown function (DUF885); Region: DUF885; pfam05960
929556002787	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
929556002788	non-specific DNA binding site [nucleotide binding]; other site
929556002789	salt bridge; other site
929556002790	sequence-specific DNA binding site [nucleotide binding]; other site
929556002791	Protein of unknown function (DUF456); Region: DUF456; pfam04306
929556002792	ribonuclease R; Region: RNase_R; TIGR02063
929556002793	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
929556002794	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
929556002795	RNB domain; Region: RNB; pfam00773
929556002796	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
929556002797	RNA binding site [nucleotide binding]; other site
929556002798	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
929556002799	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
929556002800	substrate binding pocket [chemical binding]; other site
929556002801	chain length determination region; other site
929556002802	substrate-Mg2+ binding site; other site
929556002803	catalytic residues [active]
929556002804	aspartate-rich region 1; other site
929556002805	active site lid residues [active]
929556002806	aspartate-rich region 2; other site
929556002807	EamA-like transporter family; Region: EamA; cl17759
929556002808	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
929556002809	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556002810	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556002811	Helix-turn-helix domain; Region: HTH_18; pfam12833
929556002812	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
929556002813	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
929556002814	DNA binding site [nucleotide binding]
929556002815	active site
929556002816	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
929556002817	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
929556002818	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u2; cd11494
929556002819	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
929556002820	Na binding site [ion binding]; other site
929556002821	Lipase (class 3).  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface.  A typical feature of lipases is "interfacial activation," the...; Region: Lipase_3; cd00519
929556002822	active site flap/lid [active]
929556002823	nucleophilic elbow; other site
929556002824	catalytic triad [active]
929556002825	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
929556002826	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
929556002827	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556002828	S-adenosylmethionine binding site [chemical binding]; other site
929556002829	Predicted ATPases of PP-loop superfamily [General function prediction only]; Region: COG2102
929556002830	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
929556002831	Ligand Binding Site [chemical binding]; other site
929556002832	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
929556002833	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
929556002834	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
929556002835	Phosphotransferase enzyme family; Region: APH; pfam01636
929556002836	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
929556002837	active site
929556002838	ATP binding site [chemical binding]; other site
929556002839	substrate binding site [chemical binding]; other site
929556002840	4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; Region: GabT; COG0160
929556002841	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
929556002842	inhibitor-cofactor binding pocket; inhibition site
929556002843	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556002844	catalytic residue [active]
929556002845	alpha-glucosidase; Provisional; Region: PRK10137
929556002846	Trehalase; Region: Trehalase; cl17346
929556002847	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
929556002848	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
929556002849	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
929556002850	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
929556002851	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
929556002852	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556002853	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556002854	Secretin and TonB N terminus short domain; Region: STN; pfam07660
929556002855	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556002856	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556002857	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556002858	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556002859	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
929556002860	FecR protein; Region: FecR; pfam04773
929556002861	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
929556002862	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556002863	DNA binding residues [nucleotide binding]
929556002864	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
929556002865	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
929556002866	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
929556002867	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
929556002868	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929556002869	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
929556002870	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
929556002871	Ligand Binding Site [chemical binding]; other site
929556002872	Domain of unknown function (DUF4142); Region: DUF4142; pfam13628
929556002873	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
929556002874	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
929556002875	Topoisomerase IB [DNA replication, recombination, and repair]; Region: COG3569
929556002876	DNA topoisomerase IB, C-terminal catalytic domain. Topoisomerase I promotes the relaxation of both positive and negative DNA superhelical tension by introducing a transient single-stranded break in duplex DNA. This function is vital for the processes of...; Region: Topo_IB_C; cd00659
929556002877	active site
929556002878	DNA binding site [nucleotide binding]
929556002879	Int/Topo IB signature motif; other site
929556002880	catalytic residues [active]
929556002881	hypothetical protein; Provisional; Region: PRK10621
929556002882	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
929556002883	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
929556002884	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929556002885	ATP binding site [chemical binding]; other site
929556002886	putative Mg++ binding site [ion binding]; other site
929556002887	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929556002888	nucleotide binding region [chemical binding]; other site
929556002889	ATP-binding site [chemical binding]; other site
929556002890	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
929556002891	RecX family; Region: RecX; pfam02631
929556002892	putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase; Provisional; Region: PRK11930
929556002893	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
929556002894	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
929556002895	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
929556002896	active site
929556002897	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
929556002898	dimer interface [polypeptide binding]; other site
929556002899	substrate binding site [chemical binding]; other site
929556002900	catalytic residues [active]
929556002901	Protein of unknown function (DUF502); Region: DUF502; cl01107
929556002902	hypothetical protein; Provisional; Region: PRK10279
929556002903	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
929556002904	active site
929556002905	nucleophile elbow; other site
929556002906	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
929556002907	Na(+)/iodide (NIS) and Na(+)/multivitamin (SMVT) cotransporters, and related proteins; solute binding domain; Region: SLC5sbd_NIS-like; cd10326
929556002908	Na binding site [ion binding]; other site
929556002909	recombination protein RecR; Reviewed; Region: recR; PRK00076
929556002910	RecR protein; Region: RecR; pfam02132
929556002911	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
929556002912	putative active site [active]
929556002913	putative metal-binding site [ion binding]; other site
929556002914	tetramer interface [polypeptide binding]; other site
929556002915	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929556002916	short chain dehydrogenase; Provisional; Region: PRK06181
929556002917	NAD(P) binding site [chemical binding]; other site
929556002918	active site
929556002919	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
929556002920	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
929556002921	substrate binding pocket [chemical binding]; other site
929556002922	Inward rectifier potassium channel; Region: IRK; pfam01007
929556002923	Uncharacterized conserved protein [Function unknown]; Region: COG1284
929556002924	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
929556002925	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
929556002926	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5368
929556002927	Putative glucoamylase; Region: Glycoamylase; pfam10091
929556002928	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
929556002929	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
929556002930	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
929556002931	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
929556002932	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
929556002933	active site
929556002934	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
929556002935	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
929556002936	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556002937	catalytic residue [active]
929556002938	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
929556002939	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
929556002940	substrate binding site [chemical binding]; other site
929556002941	active site
929556002942	catalytic residues [active]
929556002943	heterodimer interface [polypeptide binding]; other site
929556002944	Na+/H+ antiporter 1; Region: Na_H_antiport_1; cl01133
929556002945	HPP family; Region: HPP; pfam04982
929556002946	PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen...; Region: PAP2_haloperoxidase; cd03398
929556002947	active site
929556002948	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
929556002949	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
929556002950	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
929556002951	Peptidase C25 family N-terminal domain, found in Arg-gingipain (Rgp), Lys-gingipain (Kgp) and related proteins; Region: Peptidase_C25_N; cl03181
929556002952	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
929556002953	EcsC protein family; Region: EcsC; pfam12787
929556002954	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
929556002955	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
929556002956	putative dimer interface [polypeptide binding]; other site
929556002957	putative anticodon binding site; other site
929556002958	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
929556002959	homodimer interface [polypeptide binding]; other site
929556002960	motif 1; other site
929556002961	motif 2; other site
929556002962	active site
929556002963	motif 3; other site
929556002964	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
929556002965	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
929556002966	CoA-ligase; Region: Ligase_CoA; pfam00549
929556002967	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_2; cd09618
929556002968	putative ligand binding site [chemical binding]; other site
929556002969	integral membrane protein; Region: integ_memb_HG; TIGR03954
929556002970	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
929556002971	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
929556002972	Walker A/P-loop; other site
929556002973	ATP binding site [chemical binding]; other site
929556002974	Q-loop/lid; other site
929556002975	ABC transporter signature motif; other site
929556002976	Walker B; other site
929556002977	D-loop; other site
929556002978	H-loop/switch region; other site
929556002979	carbamoyl phosphate synthase-like protein; Provisional; Region: PRK12767
929556002980	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
929556002981	4Fe-4S single cluster domain; Region: Fer4_15; pfam13459
929556002982	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
929556002983	Peptidase family U32; Region: Peptidase_U32; pfam01136
929556002984	Haem-binding domain; Region: Haem_bd; pfam14376
929556002985	Domain of unknown function (DUF386); Region: DUF386; cl01047
929556002986	TIGR03118 family protein; Region: PEPCTERM_chp_1
929556002987	PIN domain; Region: PIN_3; cl17397
929556002988	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
929556002989	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
929556002990	Walker A/P-loop; other site
929556002991	ATP binding site [chemical binding]; other site
929556002992	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; pfam06470
929556002993	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
929556002994	ABC transporter signature motif; other site
929556002995	Walker B; other site
929556002996	D-loop; other site
929556002997	H-loop/switch region; other site
929556002998	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
929556002999	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
929556003000	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
929556003001	putative acyl-acceptor binding pocket; other site
929556003002	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556003003	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
929556003004	putative substrate translocation pore; other site
929556003005	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
929556003006	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
929556003007	active site
929556003008	catalytic tetrad [active]
929556003009	glyceraldehyde-3-phosphate dehydrogenase; Reviewed; Region: PRK08289
929556003010	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
929556003011	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
929556003012	RNA polymerase sigma factor, cyanobacterial RpoD-like family; Region: Sig70-cyanoRpoD; TIGR02997
929556003013	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
929556003014	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556003015	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
929556003016	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556003017	DNA binding residues [nucleotide binding]
929556003018	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
929556003019	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
929556003020	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
929556003021	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929556003022	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
929556003023	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556003024	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556003025	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
929556003026	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556003027	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556003028	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556003029	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
929556003030	Predicted membrane protein [Function unknown]; Region: COG2259
929556003031	Peptidase S46; Region: Peptidase_S46; pfam10459
929556003032	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
929556003033	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
929556003034	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
929556003035	dimerization interface [polypeptide binding]; other site
929556003036	ATP binding site [chemical binding]; other site
929556003037	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
929556003038	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
929556003039	A new structural DNA glycosylase; Region: AlkD_like; cd06561
929556003040	active site
929556003041	Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968
929556003042	Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437
929556003043	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
929556003044	CAAX protease self-immunity; Region: Abi; pfam02517
929556003045	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
929556003046	Uncharacterized conserved protein [Function unknown]; Region: COG3379
929556003047	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; cl17415
929556003048	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
929556003049	calcium mediated ligand binding site; other site
929556003050	intermolecular salt bridges; other site
929556003051	Uncharacterized conserved protein [Function unknown]; Region: COG3379
929556003052	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; cl17415
929556003053	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
929556003054	calcium mediated ligand binding site; other site
929556003055	intermolecular salt bridges; other site
929556003056	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5368
929556003057	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
929556003058	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
929556003059	Ku protein, prokaryotic; Region: Ku_bact; TIGR02772
929556003060	Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku. The alignment includes the core domain shared by the prokaryotic YkoV-like proteins and the eukaryotic Ku70 and Ku80. The prokaryotic Ku...; Region: KU_like; cd00789
929556003061	putative DNA binding site [nucleotide binding]; other site
929556003062	putative homodimer interface [polypeptide binding]; other site
929556003063	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556003064	binding surface
929556003065	TPR repeat; Region: TPR_11; pfam13414
929556003066	TPR motif; other site
929556003067	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556003068	binding surface
929556003069	TPR motif; other site
929556003070	TPR repeat; Region: TPR_11; pfam13414
929556003071	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
929556003072	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
929556003073	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
929556003074	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
929556003075	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
929556003076	dimerization interface [polypeptide binding]; other site
929556003077	ATP binding site [chemical binding]; other site
929556003078	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
929556003079	dimerization interface [polypeptide binding]; other site
929556003080	ATP binding site [chemical binding]; other site
929556003081	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; pfam05708
929556003082	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
929556003083	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556003084	S-adenosylmethionine binding site [chemical binding]; other site
929556003085	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
929556003086	active site
929556003087	metal binding site [ion binding]; metal-binding site
929556003088	homotetramer interface [polypeptide binding]; other site
929556003089	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
929556003090	AMP binding site [chemical binding]; other site
929556003091	metal binding site [ion binding]; metal-binding site
929556003092	active site
929556003093	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
929556003094	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
929556003095	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556003096	catalytic residues [active]
929556003097	Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic...; Region: PRX_like1; cd02969
929556003098	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556003099	putative catalytic residue [active]
929556003100	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
929556003101	active site
929556003102	catalytic site [active]
929556003103	substrate binding site [chemical binding]; other site
929556003104	Response regulator receiver domain; Region: Response_reg; pfam00072
929556003105	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556003106	active site
929556003107	phosphorylation site [posttranslational modification]
929556003108	intermolecular recognition site; other site
929556003109	dimerization interface [polypeptide binding]; other site
929556003110	PAS domain S-box; Region: sensory_box; TIGR00229
929556003111	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
929556003112	putative active site [active]
929556003113	heme pocket [chemical binding]; other site
929556003114	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556003115	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556003116	ATP binding site [chemical binding]; other site
929556003117	Mg2+ binding site [ion binding]; other site
929556003118	G-X-G motif; other site
929556003119	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
929556003120	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
929556003121	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
929556003122	catalytic core [active]
929556003123	Surface antigen; Region: Bac_surface_Ag; pfam01103
929556003124	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; cl17194
929556003125	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
929556003126	Predicted flavoproteins [General function prediction only]; Region: COG2081
929556003127	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
929556003128	TraB family; Region: TraB; pfam01963
929556003129	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
929556003130	active site
929556003131	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
929556003132	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
929556003133	putative ATP binding site [chemical binding]; other site
929556003134	putative substrate interface [chemical binding]; other site
929556003135	Cupin domain; Region: Cupin_2; cl17218
929556003136	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
929556003137	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556003138	Protein of unknown function (DUF3307); Region: DUF3307; pfam11750
929556003139	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
929556003140	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
929556003141	active site
929556003142	Zn binding site [ion binding]; other site
929556003143	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
929556003144	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
929556003145	active site
929556003146	Zn binding site [ion binding]; other site
929556003147	Domain of unknown function (DUF4399); Region: DUF4399; pfam14347
929556003148	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
929556003149	DinB family; Region: DinB; cl17821
929556003150	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556003151	hypothetical protein; Provisional; Region: PRK08262
929556003152	M20 Peptidase, carboxypeptidase yscS; Region: M20_yscS; cd05674
929556003153	metal binding site [ion binding]; metal-binding site
929556003154	FAD-linked oxidoreductase; Region: bact_FAD_ox; TIGR01679
929556003155	FAD binding domain; Region: FAD_binding_4; pfam01565
929556003156	D-arabinono-1,4-lactone oxidase; Region: ALO; pfam04030
929556003157	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes Similar to D-Serine Dehydratase and D-Threonine Aldolase, Unknown Group 2; Region: PLPDE_III_DSD_D-TA_like_2; cd06813
929556003158	dimer interface [polypeptide binding]; other site
929556003159	Predicted amino acid aldolase or racemase [Amino acid transport and metabolism]; Region: COG3616
929556003160	active site
929556003161	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
929556003162	substrate binding site [chemical binding]; other site
929556003163	catalytic residue [active]
929556003164	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
929556003165	dimerization interface [polypeptide binding]; other site
929556003166	putative DNA binding site [nucleotide binding]; other site
929556003167	putative Zn2+ binding site [ion binding]; other site
929556003168	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
929556003169	putative hydrophobic ligand binding site [chemical binding]; other site
929556003170	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
929556003171	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
929556003172	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
929556003173	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
929556003174	active site
929556003175	dimer interface [polypeptide binding]; other site
929556003176	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
929556003177	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
929556003178	active site
929556003179	FMN binding site [chemical binding]; other site
929556003180	substrate binding site [chemical binding]; other site
929556003181	3Fe-4S cluster binding site [ion binding]; other site
929556003182	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
929556003183	domain interface; other site
929556003184	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
929556003185	active site clefts [active]
929556003186	zinc binding site [ion binding]; other site
929556003187	dimer interface [polypeptide binding]; other site
929556003188	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK05808
929556003189	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
929556003190	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
929556003191	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
929556003192	Ferritin-like domain; Region: Ferritin; pfam00210
929556003193	ferroxidase diiron center [ion binding]; other site
929556003194	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
929556003195	FAD binding domain; Region: FAD_binding_4; pfam01565
929556003196	Berberine and berberine like; Region: BBE; pfam08031
929556003197	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
929556003198	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
929556003199	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556003200	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
929556003201	AAA domain; Region: AAA_26; pfam13500
929556003202	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
929556003203	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
929556003204	active site
929556003205	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
929556003206	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
929556003207	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929556003208	catalytic residue [active]
929556003209	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
929556003210	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
929556003211	Coenzyme A binding pocket [chemical binding]; other site
929556003212	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
929556003213	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929556003214	non-specific DNA binding site [nucleotide binding]; other site
929556003215	salt bridge; other site
929556003216	sequence-specific DNA binding site [nucleotide binding]; other site
929556003217	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
929556003218	Catalytic site [active]
929556003219	Nucleotidyltransferase/DNA polymerase involved in DNA repair [DNA replication, recombination, and repair]; Region: DinP; COG0389
929556003220	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
929556003221	active site
929556003222	DNA binding site [nucleotide binding]
929556003223	GIY-YIG nuclease domain superfamily; Region: GIY-YIG_SF; cl15257
929556003224	GIY-YIG motif/motif A; other site
929556003225	active site
929556003226	catalytic site [active]
929556003227	metal binding site [ion binding]; metal-binding site
929556003228	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556003229	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556003230	ligand binding site [chemical binding]; other site
929556003231	flexible hinge region; other site
929556003232	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
929556003233	putative switch regulator; other site
929556003234	non-specific DNA interactions [nucleotide binding]; other site
929556003235	DNA binding site [nucleotide binding]
929556003236	sequence specific DNA binding site [nucleotide binding]; other site
929556003237	putative cAMP binding site [chemical binding]; other site
929556003238	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
929556003239	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
929556003240	Heavy-metal-associated domain; Region: HMA; pfam00403
929556003241	metal-binding site [ion binding]
929556003242	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929556003243	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929556003244	motif II; other site
929556003245	Cytochrome oxidase maturation protein cbb3-type; Region: CcoS; pfam03597
929556003246	putative bifunctional cbb3-type cytochrome c oxidase subunit I/II; Provisional; Region: PRK14485
929556003247	Cytochrome cbb3 oxidase subunit I.  Cytochrome cbb3 oxidase, the terminal oxidase in the respiratory chains of proteobacteria, is a multi-chain transmembrane protein located in the cell membrane. Like other cytochrome oxidases, it catalyzes the reduction...; Region: cbb3_Oxidase_I; cd01661
929556003248	Low-spin heme binding site [chemical binding]; other site
929556003249	Putative water exit pathway; other site
929556003250	Binuclear center (active site) [active]
929556003251	Putative proton exit pathway; other site
929556003252	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; pfam02433
929556003253	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
929556003254	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
929556003255	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
929556003256	4Fe-4S binding domain; Region: Fer4_5; pfam12801
929556003257	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
929556003258	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
929556003259	FixH; Region: FixH; pfam05751
929556003260	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3198
929556003261	Family description; Region: DsbD_2; pfam13386
929556003262	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
929556003263	Fasciclin domain; Region: Fasciclin; pfam02469
929556003264	phosphonoacetate hydrolase; Region: hydr_PhnA; TIGR02335
929556003265	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
929556003266	Peptidase MA superfamily; Region: Peptidase_MA_2; pfam13485
929556003267	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
929556003268	Surface antigen; Region: Bac_surface_Ag; pfam01103
929556003269	Transglycosylase; Region: Transgly; pfam00912
929556003270	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
929556003271	Protein of unknown function DUF72; Region: DUF72; pfam01904
929556003272	methionine sulfoxide reductase A; Provisional; Region: PRK14054
929556003273	Esterase-like activity of phytase; Region: Phytase-like; pfam13449
929556003274	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4246
929556003275	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
929556003276	active site
929556003277	C-N hydrolase family amidase; Provisional; Region: PRK10438
929556003278	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
929556003279	putative active site [active]
929556003280	catalytic triad [active]
929556003281	dimer interface [polypeptide binding]; other site
929556003282	multimer interface [polypeptide binding]; other site
929556003283	methionine aminotransferase; Validated; Region: PRK09082
929556003284	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
929556003285	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556003286	homodimer interface [polypeptide binding]; other site
929556003287	catalytic residue [active]
929556003288	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
929556003289	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
929556003290	DoxX-like family; Region: DoxX_2; pfam13564
929556003291	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_1; cd07818
929556003292	putative hydrophobic ligand binding site [chemical binding]; other site
929556003293	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
929556003294	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
929556003295	TM-ABC transporter signature motif; other site
929556003296	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
929556003297	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556003298	Walker A/P-loop; other site
929556003299	ATP binding site [chemical binding]; other site
929556003300	Q-loop/lid; other site
929556003301	ABC transporter signature motif; other site
929556003302	Walker B; other site
929556003303	D-loop; other site
929556003304	H-loop/switch region; other site
929556003305	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
929556003306	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
929556003307	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
929556003308	N-terminal plug; other site
929556003309	ligand-binding site [chemical binding]; other site
929556003310	Predicted ATPases of PP-loop superfamily [General function prediction only]; Region: COG2102
929556003311	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_IV; cd01994
929556003312	Ligand Binding Site [chemical binding]; other site
929556003313	NAD-dependent deacetylase; Provisional; Region: PRK00481
929556003314	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
929556003315	NAD+ binding site [chemical binding]; other site
929556003316	substrate binding site [chemical binding]; other site
929556003317	Zn binding site [ion binding]; other site
929556003318	Methyltransferase domain; Region: Methyltransf_32; pfam13679
929556003319	Methyltransferase domain; Region: Methyltransf_31; pfam13847
929556003320	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
929556003321	active site
929556003322	L-fucose transporter; Provisional; Region: PRK10133; cl17665
929556003323	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
929556003324	Protein of unknown function (DUF2905); Region: DUF2905; pfam11146
929556003325	Peptidase S46; Region: Peptidase_S46; pfam10459
929556003326	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
929556003327	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
929556003328	GAF domain; Region: GAF_2; pfam13185
929556003329	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
929556003330	active site
929556003331	DNA binding site [nucleotide binding]
929556003332	kynureninase; Region: kynureninase; TIGR01814
929556003333	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
929556003334	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929556003335	catalytic residue [active]
929556003336	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
929556003337	active site
929556003338	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
929556003339	Histone deacetylase class IV also known as histone deacetylase 11; Region: HDAC_classIV; cd09993
929556003340	putative active site [active]
929556003341	Zn binding site [ion binding]; other site
929556003342	multidrug efflux protein; Reviewed; Region: PRK01766
929556003343	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
929556003344	cation binding site [ion binding]; other site
929556003345	Divergent AAA domain; Region: AAA_4; pfam04326
929556003346	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
929556003347	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
929556003348	active site 2 [active]
929556003349	active site 1 [active]
929556003350	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
929556003351	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
929556003352	active site
929556003353	NAD binding site [chemical binding]; other site
929556003354	metal binding site [ion binding]; metal-binding site
929556003355	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556003356	putative substrate translocation pore; other site
929556003357	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
929556003358	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
929556003359	DNA gyrase subunit A; Validated; Region: PRK05560
929556003360	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
929556003361	CAP-like domain; other site
929556003362	active site
929556003363	primary dimer interface [polypeptide binding]; other site
929556003364	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
929556003365	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
929556003366	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
929556003367	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
929556003368	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
929556003369	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556003370	binding surface
929556003371	TPR motif; other site
929556003372	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556003373	binding surface
929556003374	TPR motif; other site
929556003375	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
929556003376	MgtE intracellular N domain; Region: MgtE_N; smart00924
929556003377	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
929556003378	Divalent cation transporter; Region: MgtE; pfam01769
929556003379	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
929556003380	Ligand binding site; other site
929556003381	Putative Catalytic site; other site
929556003382	DXD motif; other site
929556003383	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
929556003384	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556003385	putative substrate translocation pore; other site
929556003386	POT family; Region: PTR2; cl17359
929556003387	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
929556003388	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556003389	putative substrate translocation pore; other site
929556003390	POT family; Region: PTR2; cl17359
929556003391	POT family; Region: PTR2; cl17359
929556003392	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
929556003393	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
929556003394	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556003395	GAF domain; Region: GAF_2; pfam13185
929556003396	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
929556003397	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
929556003398	active site
929556003399	metal binding site [ion binding]; metal-binding site
929556003400	Surface antigen; Region: Bac_surface_Ag; pfam01103
929556003401	SdiA-regulated; Region: SdiA-regulated; cd09971
929556003402	putative active site [active]
929556003403	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929556003404	Zn2+ binding site [ion binding]; other site
929556003405	Mg2+ binding site [ion binding]; other site
929556003406	polyphosphate kinase; Provisional; Region: PRK05443
929556003407	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
929556003408	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
929556003409	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
929556003410	domain interface [polypeptide binding]; other site
929556003411	active site
929556003412	catalytic site [active]
929556003413	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
929556003414	domain interface [polypeptide binding]; other site
929556003415	active site
929556003416	catalytic site [active]
929556003417	acetyl-CoA C-acetyltransferase; Region: PLN02644
929556003418	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
929556003419	dimer interface [polypeptide binding]; other site
929556003420	active site
929556003421	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
929556003422	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
929556003423	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929556003424	Zn2+ binding site [ion binding]; other site
929556003425	Mg2+ binding site [ion binding]; other site
929556003426	hypothetical protein; Region: PHA02126
929556003427	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556003428	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
929556003429	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
929556003430	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929556003431	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
929556003432	Soluble P-type ATPase [General function prediction only]; Region: COG4087
929556003433	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
929556003434	6-phosphofructokinase 2; Provisional; Region: PRK10294
929556003435	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
929556003436	putative substrate binding site [chemical binding]; other site
929556003437	putative ATP binding site [chemical binding]; other site
929556003438	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
929556003439	Universal stress protein family; Region: Usp; pfam00582
929556003440	phosphoenolpyruvate synthase; Validated; Region: PRK06464
929556003441	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
929556003442	Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848
929556003443	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
929556003444	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
929556003445	PAS domain S-box; Region: sensory_box; TIGR00229
929556003446	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
929556003447	putative active site [active]
929556003448	heme pocket [chemical binding]; other site
929556003449	Fms-interacting protein; Region: FimP; pfam09766
929556003450	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556003451	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556003452	dimer interface [polypeptide binding]; other site
929556003453	phosphorylation site [posttranslational modification]
929556003454	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556003455	ATP binding site [chemical binding]; other site
929556003456	Mg2+ binding site [ion binding]; other site
929556003457	G-X-G motif; other site
929556003458	Response regulator receiver domain; Region: Response_reg; pfam00072
929556003459	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556003460	active site
929556003461	phosphorylation site [posttranslational modification]
929556003462	intermolecular recognition site; other site
929556003463	dimerization interface [polypeptide binding]; other site
929556003464	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556003465	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556003466	ligand binding site [chemical binding]; other site
929556003467	flexible hinge region; other site
929556003468	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
929556003469	ATP cone domain; Region: ATP-cone; pfam03477
929556003470	Restriction endonuclease; Region: Mrr_cat; pfam04471
929556003471	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
929556003472	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
929556003473	putative ligand binding site [chemical binding]; other site
929556003474	putative NAD binding site [chemical binding]; other site
929556003475	catalytic site [active]
929556003476	Domain of unknown function (DUF1975); Region: DUF1975; pfam09318
929556003477	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
929556003478	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
929556003479	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
929556003480	dimerization interface [polypeptide binding]; other site
929556003481	metal binding site [ion binding]; metal-binding site
929556003482	Helix-turn-helix domain; Region: HTH_18; pfam12833
929556003483	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556003484	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
929556003485	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
929556003486	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
929556003487	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
929556003488	putative active site [active]
929556003489	catalytic site [active]
929556003490	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
929556003491	putative active site [active]
929556003492	catalytic site [active]
929556003493	Cupin domain; Region: Cupin_2; cl17218
929556003494	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
929556003495	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
929556003496	DNA-binding site [nucleotide binding]; DNA binding site
929556003497	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
929556003498	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556003499	homodimer interface [polypeptide binding]; other site
929556003500	catalytic residue [active]
929556003501	GNAT acetyltransferase; Region: GNAT_acetyltran; pfam12746
929556003502	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
929556003503	Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059
929556003504	chromate transporter, chromate ion transporter (CHR) family; Region: 2A51; TIGR00937
929556003505	Chromate transporter; Region: Chromate_transp; pfam02417
929556003506	Chromate resistance exported protein; Region: Chrome_Resist; pfam09828
929556003507	Chromate resistance exported protein; Region: Chrome_Resist; pfam09828
929556003508	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556003509	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556003510	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556003511	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
929556003512	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
929556003513	Sulfatase; Region: Sulfatase; pfam00884
929556003514	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
929556003515	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556003516	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556003517	DNA binding residues [nucleotide binding]
929556003518	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
929556003519	FecR protein; Region: FecR; pfam04773
929556003520	Secretin and TonB N terminus short domain; Region: STN; pfam07660
929556003521	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556003522	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556003523	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556003524	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556003525	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556003526	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
929556003527	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556003528	catalytic residues [active]
929556003529	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
929556003530	Beta-galactosidase jelly roll domain; Region: BetaGal_dom4_5; pfam13364
929556003531	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
929556003532	sugar binding site [chemical binding]; other site
929556003533	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556003534	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556003535	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556003536	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556003537	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556003538	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556003539	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
929556003540	DNA-binding site [nucleotide binding]; DNA binding site
929556003541	Transcriptional regulators [Transcription]; Region: PurR; COG1609
929556003542	Ligand-binding domain of a transcription repressor, FucR, which functions as a molecular sensor of L-fucose availability; Region: PBP1_FucR_like; cd06276
929556003543	putative dimerization interface [polypeptide binding]; other site
929556003544	putative ligand binding site [chemical binding]; other site
929556003545	alpha-galactosidase; Region: PLN02808; cl17638
929556003546	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
929556003547	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929556003548	Zn2+ binding site [ion binding]; other site
929556003549	Mg2+ binding site [ion binding]; other site
929556003550	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
929556003551	dimerization interface [polypeptide binding]; other site
929556003552	metal binding site [ion binding]; metal-binding site
929556003553	hydroperoxidase II; Provisional; Region: katE; PRK11249
929556003554	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
929556003555	tetramer interface [polypeptide binding]; other site
929556003556	heme binding pocket [chemical binding]; other site
929556003557	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
929556003558	domain interactions; other site
929556003559	Domain of unknown function (DUF4142); Region: DUF4142; pfam13628
929556003560	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
929556003561	dimerization interface [polypeptide binding]; other site
929556003562	metal binding site [ion binding]; metal-binding site
929556003563	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
929556003564	dinuclear metal binding motif [ion binding]; other site
929556003565	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556003566	active site
929556003567	phosphorylation site [posttranslational modification]
929556003568	intermolecular recognition site; other site
929556003569	dimerization interface [polypeptide binding]; other site
929556003570	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
929556003571	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
929556003572	putative active site [active]
929556003573	heme pocket [chemical binding]; other site
929556003574	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556003575	dimer interface [polypeptide binding]; other site
929556003576	phosphorylation site [posttranslational modification]
929556003577	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556003578	ATP binding site [chemical binding]; other site
929556003579	Mg2+ binding site [ion binding]; other site
929556003580	G-X-G motif; other site
929556003581	CHASE3 domain; Region: CHASE3; pfam05227
929556003582	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556003583	dimer interface [polypeptide binding]; other site
929556003584	phosphorylation site [posttranslational modification]
929556003585	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556003586	ATP binding site [chemical binding]; other site
929556003587	G-X-G motif; other site
929556003588	Domain of unknown function (DUF2383); Region: DUF2383; pfam09537
929556003589	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556003590	Response regulator receiver domain; Region: Response_reg; pfam00072
929556003591	active site
929556003592	phosphorylation site [posttranslational modification]
929556003593	intermolecular recognition site; other site
929556003594	dimerization interface [polypeptide binding]; other site
929556003595	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556003596	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556003597	dimer interface [polypeptide binding]; other site
929556003598	phosphorylation site [posttranslational modification]
929556003599	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556003600	ATP binding site [chemical binding]; other site
929556003601	Mg2+ binding site [ion binding]; other site
929556003602	G-X-G motif; other site
929556003603	Response regulator receiver domain; Region: Response_reg; pfam00072
929556003604	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556003605	active site
929556003606	phosphorylation site [posttranslational modification]
929556003607	intermolecular recognition site; other site
929556003608	dimerization interface [polypeptide binding]; other site
929556003609	PAS fold; Region: PAS_4; pfam08448
929556003610	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
929556003611	putative active site [active]
929556003612	heme pocket [chemical binding]; other site
929556003613	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
929556003614	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
929556003615	putative active site [active]
929556003616	heme pocket [chemical binding]; other site
929556003617	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556003618	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556003619	dimer interface [polypeptide binding]; other site
929556003620	phosphorylation site [posttranslational modification]
929556003621	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556003622	ATP binding site [chemical binding]; other site
929556003623	Mg2+ binding site [ion binding]; other site
929556003624	G-X-G motif; other site
929556003625	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
929556003626	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
929556003627	DNA-binding site [nucleotide binding]; DNA binding site
929556003628	UTRA domain; Region: UTRA; pfam07702
929556003629	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
929556003630	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
929556003631	nucleotide binding site [chemical binding]; other site
929556003632	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
929556003633	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
929556003634	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
929556003635	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556003636	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556003637	N-terminal catalytic domain of mainly uncharacterized eukaryotic proteins similar to alpha-mannosidases; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_like_1; cd10791
929556003638	putative active site [active]
929556003639	catalytic site [active]
929556003640	Glycosyl hydrolases family 38 C-terminal domain; Region: Glyco_hydro_38C; pfam07748
929556003641	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556003642	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556003643	ligand binding site [chemical binding]; other site
929556003644	flexible hinge region; other site
929556003645	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
929556003646	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
929556003647	active site
929556003648	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929556003649	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929556003650	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556003651	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
929556003652	active site
929556003653	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
929556003654	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556003655	Domain of unknown function (DUF4304); Region: DUF4304; pfam14137
929556003656	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556003657	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
929556003658	Integrase core domain; Region: rve; pfam00665
929556003659	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556003660	Type IV pilin PilA; Region: Pilin_PilA; pfam14245
929556003661	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
929556003662	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
929556003663	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
929556003664	Walker A motif; other site
929556003665	ATP binding site [chemical binding]; other site
929556003666	Walker B motif; other site
929556003667	type IV pilus secretin (or competence protein) PilQ; Region: IV_pilus_PilQ; TIGR02515
929556003668	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
929556003669	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
929556003670	basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins; Region: B_zip1; cl02576
929556003671	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
929556003672	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556003673	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556003674	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
929556003675	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556003676	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
929556003677	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556003678	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
929556003679	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
929556003680	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
929556003681	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556003682	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556003683	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
929556003684	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
929556003685	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
929556003686	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
929556003687	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
929556003688	Predicted periplasmic protein (DUF2092); Region: DUF2092; cl17607
929556003689	RHS Repeat; Region: RHS_repeat; cl11982
929556003690	Transcriptional regulators [Transcription]; Region: PurR; COG1609
929556003691	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
929556003692	DNA binding site [nucleotide binding]
929556003693	domain linker motif; other site
929556003694	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
929556003695	dimerization interface [polypeptide binding]; other site
929556003696	ligand binding site [chemical binding]; other site
929556003697	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
929556003698	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
929556003699	nucleotide binding site [chemical binding]; other site
929556003700	xylose isomerase; Provisional; Region: PRK05474
929556003701	xylose isomerase; Region: xylose_isom_A; TIGR02630
929556003702	Vibrio parahaemolyticus Na(+)/galactose cotransporter (vSGLT) and related proteins; solute binding domain; Region: SLC5sbd_vSGLT; cd10325
929556003703	putative transporter; Provisional; Region: PRK10484
929556003704	Na binding site [ion binding]; other site
929556003705	substrate binding site [chemical binding]; other site
929556003706	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
929556003707	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
929556003708	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556003709	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556003710	dimer interface [polypeptide binding]; other site
929556003711	phosphorylation site [posttranslational modification]
929556003712	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556003713	ATP binding site [chemical binding]; other site
929556003714	Mg2+ binding site [ion binding]; other site
929556003715	G-X-G motif; other site
929556003716	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929556003717	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556003718	active site
929556003719	phosphorylation site [posttranslational modification]
929556003720	intermolecular recognition site; other site
929556003721	dimerization interface [polypeptide binding]; other site
929556003722	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556003723	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556003724	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
929556003725	PA14 domain; Region: PA14; cl08459
929556003726	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
929556003727	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
929556003728	putative active site [active]
929556003729	putative catalytic site [active]
929556003730	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556003731	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556003732	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556003733	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
929556003734	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556003735	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556003736	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
929556003737	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
929556003738	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
929556003739	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
929556003740	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
929556003741	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
929556003742	Domain of unknown function (DUF303); Region: DUF303; pfam03629
929556003743	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
929556003744	Domain of unknown function (DUF303); Region: DUF303; pfam03629
929556003745	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
929556003746	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
929556003747	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
929556003748	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
929556003749	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556003750	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
929556003751	binding surface
929556003752	TPR motif; other site
929556003753	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
929556003754	Histidine kinase; Region: HisKA_3; pfam07730
929556003755	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556003756	ATP binding site [chemical binding]; other site
929556003757	Mg2+ binding site [ion binding]; other site
929556003758	G-X-G motif; other site
929556003759	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
929556003760	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556003761	active site
929556003762	phosphorylation site [posttranslational modification]
929556003763	intermolecular recognition site; other site
929556003764	dimerization interface [polypeptide binding]; other site
929556003765	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
929556003766	DNA binding residues [nucleotide binding]
929556003767	dimerization interface [polypeptide binding]; other site
929556003768	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
929556003769	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
929556003770	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
929556003771	active site
929556003772	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
929556003773	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556003774	S-adenosylmethionine binding site [chemical binding]; other site
929556003775	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
929556003776	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556003777	Protein of unknown function (DUF3997); Region: DUF3997; pfam13162
929556003778	Domain of unknown function (DUF4189); Region: DUF4189; pfam13827
929556003779	Cupin domain; Region: Cupin_2; pfam07883
929556003780	Helix-turn-helix domain; Region: HTH_18; pfam12833
929556003781	Domain of unknown function (DUF718); Region: DUF718; pfam05336
929556003782	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
929556003783	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556003784	putative substrate translocation pore; other site
929556003785	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
929556003786	galactarate dehydratase; Region: galactar-dH20; TIGR03248
929556003787	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
929556003788	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
929556003789	classical (c) SDRs; Region: SDR_c; cd05233
929556003790	NAD(P) binding site [chemical binding]; other site
929556003791	active site
929556003792	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
929556003793	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
929556003794	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
929556003795	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
929556003796	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
929556003797	Amidohydrolase; Region: Amidohydro_2; pfam04909
929556003798	active site
929556003799	Peptide-N-glycosidase F, N terminal; Region: N-glycanase_N; pfam09112
929556003800	Peptide-N-glycosidase F, C terminal; Region: N-glycanase_C; pfam09113
929556003801	short chain dehydrogenase; Provisional; Region: PRK08628
929556003802	classical (c) SDRs; Region: SDR_c; cd05233
929556003803	NAD(P) binding site [chemical binding]; other site
929556003804	active site
929556003805	Alpha-L-fucosidase; Region: Alpha_L_fucos; smart00812
929556003806	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
929556003807	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
929556003808	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
929556003809	AMP-binding enzyme; Region: AMP-binding; pfam00501
929556003810	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
929556003811	acyl-activating enzyme (AAE) consensus motif; other site
929556003812	AMP binding site [chemical binding]; other site
929556003813	active site
929556003814	CoA binding site [chemical binding]; other site
929556003815	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
929556003816	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
929556003817	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929556003818	catalytic residue [active]
929556003819	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
929556003820	NADH(P)-binding; Region: NAD_binding_10; pfam13460
929556003821	NAD binding site [chemical binding]; other site
929556003822	substrate binding site [chemical binding]; other site
929556003823	putative active site [active]
929556003824	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556003825	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556003826	Domain of unknown function (DUF4142); Region: DUF4142; pfam13628
929556003827	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556003828	ATP-dependent DNA ligase; Reviewed; Region: ligD; PRK05972
929556003829	DNA polymerase Ligase (LigD); Region: LigD_N; cl11819
929556003830	Adenylation domain of Mycobacterium tuberculosis LigD and LigC-like ATP-dependent DNA ligases; Region: Adenylation_DNA_ligase_LigD_LigC; cd07906
929556003831	active site
929556003832	DNA binding site [nucleotide binding]
929556003833	The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase LigD is a DNA-binding module that is part of the catalytic core unit; Region: OBF_DNA_ligase_LigD; cd07971
929556003834	DNA binding site [nucleotide binding]
929556003835	LigD_Pol_like_2: Polymerase (Pol) domain of bacterial LigD proteins similar to Pseudomonas aeruginosa (Pae) LigD, subgroup 2. The LigD Pol domain belongs to the archaeal/eukaryal primase (AEP) superfamily. In prokaryotes, LigD along with Ku is required...; Region: LigD_Pol_like_2; cd04865
929556003836	nucleotide binding site [chemical binding]; other site
929556003837	Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku. The alignment includes the core domain shared by the prokaryotic YkoV-like proteins and the eukaryotic Ku70 and Ku80. The prokaryotic Ku...; Region: KU_like; cd00789
929556003838	putative DNA binding site [nucleotide binding]; other site
929556003839	putative homodimer interface [polypeptide binding]; other site
929556003840	YtxH-like protein; Region: YtxH; cl02079
929556003841	short chain dehydrogenase; Provisional; Region: PRK06701
929556003842	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
929556003843	NAD binding site [chemical binding]; other site
929556003844	metal binding site [ion binding]; metal-binding site
929556003845	active site
929556003846	Domain of unknown function (DUF2383); Region: DUF2383; cl17556
929556003847	Predicted membrane protein [Function unknown]; Region: COG2323
929556003848	YtxH-like protein; Region: YtxH; cl02079
929556003849	Domain of unknown function (DUF4142); Region: DUF4142; pfam13628
929556003850	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556003851	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556003852	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556003853	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556003854	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556003855	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
929556003856	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
929556003857	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
929556003858	Domain of Unknown Function (DUF1543); Region: DUF1543; pfam07566
929556003859	Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625
929556003860	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556003861	SurA N-terminal domain; Region: SurA_N; pfam09312
929556003862	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556003863	SnoaL-like domain; Region: SnoaL_2; pfam12680
929556003864	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
929556003865	Ferritin-like domain; Region: Ferritin; pfam00210
929556003866	ferroxidase diiron center [ion binding]; other site
929556003867	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
929556003868	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
929556003869	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
929556003870	DinB family; Region: DinB; cl17821
929556003871	DinB superfamily; Region: DinB_2; pfam12867
929556003872	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
929556003873	active site
929556003874	DNA polymerase IV; Validated; Region: PRK02406
929556003875	DNA binding site [nucleotide binding]
929556003876	Predicted membrane protein [Function unknown]; Region: COG2510
929556003877	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
929556003878	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
929556003879	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
929556003880	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556003881	Outer membrane efflux protein; Region: OEP; pfam02321
929556003882	Outer membrane efflux protein; Region: OEP; pfam02321
929556003883	Cupin domain; Region: Cupin_2; cl17218
929556003884	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
929556003885	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556003886	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556003887	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
929556003888	active site
929556003889	cosubstrate binding site; other site
929556003890	substrate binding site [chemical binding]; other site
929556003891	catalytic site [active]
929556003892	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
929556003893	active site
929556003894	catalytic site [active]
929556003895	substrate binding site [chemical binding]; other site
929556003896	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
929556003897	GIY-YIG motif/motif A; other site
929556003898	active site
929556003899	catalytic site [active]
929556003900	putative DNA binding site [nucleotide binding]; other site
929556003901	metal binding site [ion binding]; metal-binding site
929556003902	MAC/Perforin domain; Region: MACPF; cl02616
929556003903	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
929556003904	Transcriptional regulators [Transcription]; Region: MarR; COG1846
929556003905	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
929556003906	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
929556003907	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556003908	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
929556003909	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556003910	putative substrate translocation pore; other site
929556003911	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556003912	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
929556003913	Staphylococcal nuclease homologues; Region: SNc; smart00318
929556003914	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cd00175
929556003915	Catalytic site; other site
929556003916	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
929556003917	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
929556003918	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
929556003919	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08641
929556003920	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
929556003921	3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme metabolism]; Region: UbiX; COG0163
929556003922	Flavoprotein; Region: Flavoprotein; pfam02441
929556003923	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
929556003924	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
929556003925	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929556003926	FeS/SAM binding site; other site
929556003927	Predicted membrane protein [Function unknown]; Region: COG2246
929556003928	GtrA-like protein; Region: GtrA; pfam04138
929556003929	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
929556003930	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
929556003931	active site
929556003932	dimerization interface [polypeptide binding]; other site
929556003933	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556003934	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556003935	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556003936	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556003937	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
929556003938	starch binding outer membrane protein SusD; Region: SusD; cl17845
929556003939	SusD family; Region: SusD; pfam07980
929556003940	SusE outer membrane protein; Region: SusE; pfam14292
929556003941	carbohydrate-binding modules from Bacteroides thetaiotaomicron SusE, SusF and similar proteins; Region: CBM_SusE-F_like; cl17376
929556003942	starch binding site [chemical binding]; other site
929556003943	carbohydrate-binding modules from Bacteroides thetaiotaomicron SusE, SusF and similar proteins; Region: CBM_SusE-F_like; cd12956
929556003944	starch binding site [chemical binding]; other site
929556003945	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
929556003946	Alpha amylase catalytic domain found in an uncharacterized protein family; Region: AmyAc_4; cd11350
929556003947	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
929556003948	active site
929556003949	catalytic site [active]
929556003950	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; pfam08712
929556003951	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
929556003952	adenylosuccinate lyase; Provisional; Region: PRK09285
929556003953	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
929556003954	tetramer interface [polypeptide binding]; other site
929556003955	active site
929556003956	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929556003957	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929556003958	Outer membrane efflux protein; Region: OEP; pfam02321
929556003959	Outer membrane efflux protein; Region: OEP; pfam02321
929556003960	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
929556003961	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
929556003962	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556003963	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
929556003964	Protein export membrane protein; Region: SecD_SecF; cl14618
929556003965	Predicted transcriptional regulators [Transcription]; Region: COG1733
929556003966	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
929556003967	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
929556003968	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
929556003969	catalytic residues [active]
929556003970	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
929556003971	Coenzyme A binding pocket [chemical binding]; other site
929556003972	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
929556003973	YCII-related domain; Region: YCII; cl00999
929556003974	DNA repair photolyase [DNA replication, recombination, and repair]; Region: SplB; COG1533
929556003975	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
929556003976	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556003977	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
929556003978	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
929556003979	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
929556003980	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
929556003981	NAD(P) binding site [chemical binding]; other site
929556003982	catalytic residues [active]
929556003983	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
929556003984	NADH dehydrogenase subunit D; Validated; Region: PRK06075
929556003985	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; pfam00329
929556003986	pyridoxamine-phosphate oxidase; Region: pdxH; TIGR00558
929556003987	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
929556003988	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
929556003989	Uncharacterized ACR, COG1678; Region: DUF179; pfam02622
929556003990	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
929556003991	ATP-grasp domain; Region: ATP-grasp; pfam02222
929556003992	AIR carboxylase; Region: AIRC; pfam00731
929556003993	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
929556003994	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
929556003995	dimer interface [polypeptide binding]; other site
929556003996	active site
929556003997	CoA binding pocket [chemical binding]; other site
929556003998	Putative hydrophobic ligand-binding SRPBCC domain of the Hsp90 co-chaperone Aha1 and related proteins; Region: SRPBCC_Aha1; cd08892
929556003999	putative hydrophobic ligand binding site [chemical binding]; other site
929556004000	putative Hsp90 binding residues [polypeptide binding]; other site
929556004001	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
929556004002	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929556004003	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929556004004	ABC transporter; Region: ABC_tran_2; pfam12848
929556004005	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929556004006	RDD family; Region: RDD; pfam06271
929556004007	RDD family; Region: RDD; pfam06271
929556004008	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708
929556004009	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
929556004010	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
929556004011	active site
929556004012	Dihydroneopterin aldolase; Region: FolB; pfam02152
929556004013	active site
929556004014	FAD binding domain; Region: FAD_binding_4; pfam01565
929556004015	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
929556004016	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
929556004017	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
929556004018	putative dimer interface [polypeptide binding]; other site
929556004019	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
929556004020	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
929556004021	polyphosphate kinase; Provisional; Region: PRK05443
929556004022	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
929556004023	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
929556004024	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
929556004025	domain interface [polypeptide binding]; other site
929556004026	active site
929556004027	catalytic site [active]
929556004028	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
929556004029	domain interface [polypeptide binding]; other site
929556004030	active site
929556004031	catalytic site [active]
929556004032	exopolyphosphatase; Region: exo_poly_only; TIGR03706
929556004033	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
929556004034	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556004035	Coenzyme A binding pocket [chemical binding]; other site
929556004036	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
929556004037	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
929556004038	beta-D-glucuronidase; Provisional; Region: PRK10150
929556004039	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
929556004040	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
929556004041	Di-glucose binding within endoplasmic reticulum; Region: Malectin; pfam11721
929556004042	Sulfatase; Region: Sulfatase; cl17466
929556004043	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
929556004044	Glycosyl hydrolase family 43; Region: GH43_3; cd08982
929556004045	active site
929556004046	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
929556004047	sugar binding site [chemical binding]; other site
929556004048	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
929556004049	Interdomain contacts; other site
929556004050	Cytokine receptor motif; other site
929556004051	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
929556004052	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
929556004053	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
929556004054	active site
929556004055	Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. This family contains catechol 1,2-dioxygenases and protocatechuate 3,4-dioxygenases which are mononuclear...; Region: intradiol_dioxygenase; cl17208
929556004056	active site
929556004057	Transcriptional regulators [Transcription]; Region: MarR; COG1846
929556004058	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
929556004059	putative DNA binding site [nucleotide binding]; other site
929556004060	putative Zn2+ binding site [ion binding]; other site
929556004061	NUMOD4 motif; Region: NUMOD4; pfam07463
929556004062	GIYX(10-11)YIG family of class I homing endonucleases C-terminus (GIY-YIG_Cterm). Homing endonucleases promote the mobility of intron or intein by recognizing and cleaving a homologous allele that lacks the sequence. They catalyze a double-strand break...; Region: GIY-YIG_Cterm; cl11508
929556004063	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
929556004064	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
929556004065	active site
929556004066	catalytic tetrad [active]
929556004067	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
929556004068	active site
929556004069	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
929556004070	Catalytic NodB homology domain of uncharacterized bacterial glycosyl transferase, group 2-like family proteins; Region: CE4_GT2-like; cd10962
929556004071	NodB motif; other site
929556004072	putative active site [active]
929556004073	putative catalytic site [active]
929556004074	putative Zn binding site [ion binding]; other site
929556004075	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
929556004076	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
929556004077	DXD motif; other site
929556004078	Peptidase family C9; Region: Peptidase_C9; pfam01707
929556004079	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556004080	TPR repeat; Region: TPR_11; pfam13414
929556004081	binding surface
929556004082	TPR motif; other site
929556004083	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
929556004084	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
929556004085	Walker A/P-loop; other site
929556004086	ATP binding site [chemical binding]; other site
929556004087	Q-loop/lid; other site
929556004088	ABC transporter signature motif; other site
929556004089	Walker B; other site
929556004090	D-loop; other site
929556004091	H-loop/switch region; other site
929556004092	nitrous oxide reductase family maturation protein NosD; Region: NosD_copper_fam; TIGR04247
929556004093	parallel beta-helix repeat (two copies); Region: para_beta_helix; TIGR03804
929556004094	YtkA-like; Region: YtkA; pfam13115
929556004095	YtkA-like; Region: YtkA; pfam13115
929556004096	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
929556004097	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556004098	NosL; Region: NosL; cl01769
929556004099	nitrous-oxide reductase, Sec-dependent; Region: nitrous_NosZ_Gp; TIGR04246
929556004100	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
929556004101	Cytochrome c; Region: Cytochrom_C; pfam00034
929556004102	Rrf2 family protein; Region: rrf2_super; TIGR00738
929556004103	Transcriptional regulator; Region: Rrf2; pfam02082
929556004104	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
929556004105	iron-sulfur cluster repair di-iron protein; Region: FeS_repair_RIC; TIGR03652
929556004106	Hemerythrin-like domain; Region: Hr-like; cd12108
929556004107	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
929556004108	dimer interface [polypeptide binding]; other site
929556004109	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_17; cd08356
929556004110	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556004111	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
929556004112	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
929556004113	active site
929556004114	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
929556004115	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556004116	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
929556004117	YceG-like family; Region: YceG; pfam02618
929556004118	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
929556004119	dimerization interface [polypeptide binding]; other site
929556004120	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
929556004121	active site residue [active]
929556004122	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
929556004123	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
929556004124	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
929556004125	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
929556004126	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
929556004127	ATP-grasp domain; Region: ATP-grasp_4; cl17255
929556004128	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
929556004129	active site
929556004130	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
929556004131	16S/18S rRNA binding site [nucleotide binding]; other site
929556004132	S13e-L30e interaction site [polypeptide binding]; other site
929556004133	25S rRNA binding site [nucleotide binding]; other site
929556004134	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
929556004135	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
929556004136	RNase E interface [polypeptide binding]; other site
929556004137	trimer interface [polypeptide binding]; other site
929556004138	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
929556004139	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
929556004140	RNase E interface [polypeptide binding]; other site
929556004141	trimer interface [polypeptide binding]; other site
929556004142	active site
929556004143	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
929556004144	putative nucleic acid binding region [nucleotide binding]; other site
929556004145	G-X-X-G motif; other site
929556004146	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
929556004147	RNA binding site [nucleotide binding]; other site
929556004148	domain interface; other site
929556004149	YceI-like domain; Region: YceI; pfam04264
929556004150	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
929556004151	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
929556004152	substrate binding site [chemical binding]; other site
929556004153	hexamer interface [polypeptide binding]; other site
929556004154	metal binding site [ion binding]; metal-binding site
929556004155	3-phosphoserine/phosphohydroxythreonine aminotransferase; Provisional; Region: PRK05355
929556004156	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929556004157	catalytic residue [active]
929556004158	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
929556004159	Phosphoglycerate dehydrogenase (PGDH) NAD-binding and catalytic domains; Region: PGDH_2; cd05303
929556004160	putative ligand binding site [chemical binding]; other site
929556004161	NAD binding site [chemical binding]; other site
929556004162	dimerization interface [polypeptide binding]; other site
929556004163	catalytic site [active]
929556004164	Fic family protein [Function unknown]; Region: COG3177
929556004165	Fic/DOC family; Region: Fic; pfam02661
929556004166	DNA helicase, putative; Region: TIGR00376
929556004167	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929556004168	ATP binding site [chemical binding]; other site
929556004169	AAA domain; Region: AAA_12; pfam13087
929556004170	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
929556004171	active site
929556004172	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
929556004173	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556004174	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c_3; pfam13589
929556004175	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556004176	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
929556004177	ATP binding site [chemical binding]; other site
929556004178	Mg2+ binding site [ion binding]; other site
929556004179	G-X-G motif; other site
929556004180	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
929556004181	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
929556004182	cofactor binding site; other site
929556004183	DNA binding site [nucleotide binding]
929556004184	substrate interaction site [chemical binding]; other site
929556004185	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
929556004186	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
929556004187	endonuclease III; Region: ENDO3c; smart00478
929556004188	minor groove reading motif; other site
929556004189	helix-hairpin-helix signature motif; other site
929556004190	substrate binding pocket [chemical binding]; other site
929556004191	active site
929556004192	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
929556004193	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
929556004194	dimerization interface [polypeptide binding]; other site
929556004195	putative DNA binding site [nucleotide binding]; other site
929556004196	putative Zn2+ binding site [ion binding]; other site
929556004197	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
929556004198	hydrophobic ligand binding site; other site
929556004199	DoxX-like family; Region: DoxX_2; pfam13564
929556004200	Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_2; cd08895
929556004201	putative hydrophobic ligand binding site [chemical binding]; other site
929556004202	MepB protein; Region: MepB; cl01985
929556004203	Protein of unknown function (DUF4256); Region: DUF4256; pfam14066
929556004204	Domain of unknown function DUF21; Region: DUF21; pfam01595
929556004205	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
929556004206	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
929556004207	Transporter associated domain; Region: CorC_HlyC; smart01091
929556004208	Cytochrome c; Region: Cytochrom_C; pfam00034
929556004209	Uncharacterized protein conserved in bacteria (DUF2252); Region: DUF2252; pfam10009
929556004210	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4320
929556004211	Periplasmic lysozyme inhibitor, I-type (PliI) and similar proteins; Region: PliI_like; cd09632
929556004212	putative inhibitory loop; other site
929556004213	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
929556004214	nudix motif; other site
929556004215	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
929556004216	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556004217	S-adenosylmethionine binding site [chemical binding]; other site
929556004218	biotin synthase; Region: bioB; TIGR00433
929556004219	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929556004220	FeS/SAM binding site; other site
929556004221	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
929556004222	WbqC-like protein family; Region: WbqC; pfam08889
929556004223	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
929556004224	putative acyl-acceptor binding pocket; other site
929556004225	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
929556004226	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
929556004227	Probable Catalytic site; other site
929556004228	metal-binding site
929556004229	FOG: CBS domain [General function prediction only]; Region: COG0517
929556004230	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
929556004231	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
929556004232	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
929556004233	dimer interface [polypeptide binding]; other site
929556004234	decamer (pentamer of dimers) interface [polypeptide binding]; other site
929556004235	catalytic triad [active]
929556004236	peroxidatic and resolving cysteines [active]
929556004237	alkylhydroperoxidase, AhpD family; Region: ahpD; TIGR00777
929556004238	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
929556004239	Uncharacterized conserved protein (DUF2235); Region: DUF2235; pfam09994
929556004240	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
929556004241	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556004242	Walker A/P-loop; other site
929556004243	ATP binding site [chemical binding]; other site
929556004244	Q-loop/lid; other site
929556004245	ABC transporter signature motif; other site
929556004246	Walker B; other site
929556004247	D-loop; other site
929556004248	H-loop/switch region; other site
929556004249	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556004250	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556004251	Walker A/P-loop; other site
929556004252	Walker A/P-loop; other site
929556004253	ATP binding site [chemical binding]; other site
929556004254	ATP binding site [chemical binding]; other site
929556004255	Q-loop/lid; other site
929556004256	ABC transporter signature motif; other site
929556004257	Walker B; other site
929556004258	D-loop; other site
929556004259	H-loop/switch region; other site
929556004260	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
929556004261	Dehydroquinase class II; Region: DHquinase_II; pfam01220
929556004262	active site
929556004263	trimer interface [polypeptide binding]; other site
929556004264	dimer interface [polypeptide binding]; other site
929556004265	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
929556004266	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
929556004267	active site
929556004268	Int/Topo IB signature motif; other site
929556004269	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
929556004270	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556004271	catalytic residues [active]
929556004272	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
929556004273	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
929556004274	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556004275	S-adenosylmethionine binding site [chemical binding]; other site
929556004276	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
929556004277	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
929556004278	catalytic motif [active]
929556004279	Zn binding site [ion binding]; other site
929556004280	RibD C-terminal domain; Region: RibD_C; pfam01872
929556004281	Uncharacterized conserved protein [Function unknown]; Region: COG1739
929556004282	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
929556004283	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
929556004284	Phosphorylase superfamily; Region: PNP_UDP_1; pfam01048
929556004285	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
929556004286	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
929556004287	NAD(P) binding site [chemical binding]; other site
929556004288	Protein of unknown function (DUF3050); Region: DUF3050; pfam11251
929556004289	Menaquinone biosynthesis; Region: VitK2_biosynth; pfam02621
929556004290	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
929556004291	catalytic core [active]
929556004292	putative menaquinone biosynthesis protein, SCO4494 family; Region: mena_SCO4494; TIGR03700
929556004293	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929556004294	FeS/SAM binding site; other site
929556004295	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
929556004296	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
929556004297	homodimer interface [polypeptide binding]; other site
929556004298	substrate-cofactor binding pocket; other site
929556004299	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556004300	catalytic residue [active]
929556004301	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
929556004302	active site clefts [active]
929556004303	zinc binding site [ion binding]; other site
929556004304	dimer interface [polypeptide binding]; other site
929556004305	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
929556004306	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
929556004307	E3 interaction surface; other site
929556004308	lipoyl attachment site [posttranslational modification]; other site
929556004309	e3 binding domain; Region: E3_binding; pfam02817
929556004310	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
929556004311	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
929556004312	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
929556004313	anti sigma factor interaction site; other site
929556004314	regulatory phosphorylation site [posttranslational modification]; other site
929556004315	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
929556004316	ATP binding site [chemical binding]; other site
929556004317	active site
929556004318	substrate binding site [chemical binding]; other site
929556004319	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
929556004320	PhoH-like protein; Region: PhoH; pfam02562
929556004321	S-adenosyl-l-methionine hydroxide adenosyltransferase; Region: SAM_adeno_trans; pfam01887
929556004322	Antibiotic biosynthesis monooxygenase; Region: ABM; pfam03992
929556004323	ABC transporter, permease/ATP-binding protein; Region: MsbA_rel; TIGR02204
929556004324	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
929556004325	ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; Region: ABC_MTABC3_MDL1_MDL2; cd03249
929556004326	Walker A/P-loop; other site
929556004327	ATP binding site [chemical binding]; other site
929556004328	Q-loop/lid; other site
929556004329	ABC transporter signature motif; other site
929556004330	Walker B; other site
929556004331	D-loop; other site
929556004332	H-loop/switch region; other site
929556004333	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
929556004334	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
929556004335	Sulfate transporter family; Region: Sulfate_transp; pfam00916
929556004336	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
929556004337	active site clefts [active]
929556004338	zinc binding site [ion binding]; other site
929556004339	dimer interface [polypeptide binding]; other site
929556004340	competence damage-inducible protein A; Provisional; Region: PRK00549
929556004341	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
929556004342	putative MPT binding site; other site
929556004343	Competence-damaged protein; Region: CinA; pfam02464
929556004344	cardiolipin synthetase; Reviewed; Region: PRK12452
929556004345	ketol-acid reductoisomerase; Validated; Region: PRK05225
929556004346	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
929556004347	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
929556004348	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
929556004349	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
929556004350	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
929556004351	putative valine binding site [chemical binding]; other site
929556004352	dimer interface [polypeptide binding]; other site
929556004353	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
929556004354	acetolactate synthase, large subunit, biosynthetic type; Region: acolac_lg; TIGR00118
929556004355	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
929556004356	PYR/PP interface [polypeptide binding]; other site
929556004357	dimer interface [polypeptide binding]; other site
929556004358	TPP binding site [chemical binding]; other site
929556004359	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
929556004360	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
929556004361	TPP-binding site [chemical binding]; other site
929556004362	dimer interface [polypeptide binding]; other site
929556004363	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
929556004364	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
929556004365	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
929556004366	homodimer interface [polypeptide binding]; other site
929556004367	substrate-cofactor binding pocket; other site
929556004368	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556004369	catalytic residue [active]
929556004370	threonine dehydratase; Validated; Region: PRK08639
929556004371	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
929556004372	tetramer interface [polypeptide binding]; other site
929556004373	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556004374	catalytic residue [active]
929556004375	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
929556004376	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
929556004377	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
929556004378	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
929556004379	active site
929556004380	metal binding site [ion binding]; metal-binding site
929556004381	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
929556004382	mce related protein; Region: MCE; pfam02470
929556004383	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
929556004384	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556004385	Walker A motif; other site
929556004386	ATP binding site [chemical binding]; other site
929556004387	Walker B motif; other site
929556004388	arginine finger; other site
929556004389	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
929556004390	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
929556004391	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
929556004392	active site
929556004393	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
929556004394	substrate binding site [chemical binding]; other site
929556004395	catalytic residues [active]
929556004396	dimer interface [polypeptide binding]; other site
929556004397	aspartate kinase III; Validated; Region: PRK09084
929556004398	AAK_AK-HSDH-like: Amino Acid Kinase Superfamily (AAK), AK-HSDH-like; this family includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK- homoserine dehydrogenase (HSDH). These aspartokinases are found in such...; Region: AAK_AK-HSDH-like; cd04243
929556004399	putative catalytic residues [active]
929556004400	nucleotide binding site [chemical binding]; other site
929556004401	aspartate binding site [chemical binding]; other site
929556004402	ACT domains located C-terminal to the catalytic domain of  the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC-like_1; cd04912
929556004403	dimer interface [polypeptide binding]; other site
929556004404	allosteric regulatory binding pocket; other site
929556004405	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
929556004406	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
929556004407	This PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily and is found in both archaea and bacteria. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible...; Region: PGM_like2; cd05800
929556004408	active site
929556004409	substrate binding site [chemical binding]; other site
929556004410	metal binding site [ion binding]; metal-binding site
929556004411	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
929556004412	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
929556004413	Walker A/P-loop; other site
929556004414	ATP binding site [chemical binding]; other site
929556004415	Q-loop/lid; other site
929556004416	ABC transporter signature motif; other site
929556004417	Walker B; other site
929556004418	D-loop; other site
929556004419	H-loop/switch region; other site
929556004420	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
929556004421	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
929556004422	Cu(I) binding site [ion binding]; other site
929556004423	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
929556004424	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
929556004425	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
929556004426	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556004427	active site
929556004428	phosphorylation site [posttranslational modification]
929556004429	intermolecular recognition site; other site
929556004430	dimerization interface [polypeptide binding]; other site
929556004431	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556004432	Walker A motif; other site
929556004433	ATP binding site [chemical binding]; other site
929556004434	Walker B motif; other site
929556004435	arginine finger; other site
929556004436	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
929556004437	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
929556004438	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
929556004439	glutaminase active site [active]
929556004440	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
929556004441	dimer interface [polypeptide binding]; other site
929556004442	active site
929556004443	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
929556004444	dimer interface [polypeptide binding]; other site
929556004445	active site
929556004446	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
929556004447	putative CoA binding site [chemical binding]; other site
929556004448	putative trimer interface [polypeptide binding]; other site
929556004449	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
929556004450	putative trimer interface [polypeptide binding]; other site
929556004451	putative CoA binding site [chemical binding]; other site
929556004452	GTP-binding protein LepA; Provisional; Region: PRK05433
929556004453	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
929556004454	G1 box; other site
929556004455	putative GEF interaction site [polypeptide binding]; other site
929556004456	GTP/Mg2+ binding site [chemical binding]; other site
929556004457	Switch I region; other site
929556004458	G2 box; other site
929556004459	G3 box; other site
929556004460	Switch II region; other site
929556004461	G4 box; other site
929556004462	G5 box; other site
929556004463	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
929556004464	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
929556004465	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
929556004466	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14185
929556004467	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
929556004468	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
929556004469	homodimer interface [polypeptide binding]; other site
929556004470	NADP binding site [chemical binding]; other site
929556004471	substrate binding site [chemical binding]; other site
929556004472	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
929556004473	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
929556004474	TPR repeat; Region: TPR_11; pfam13414
929556004475	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556004476	binding surface
929556004477	TPR motif; other site
929556004478	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
929556004479	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
929556004480	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
929556004481	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556004482	ligand binding site [chemical binding]; other site
929556004483	Predicted thiol-disulfide oxidoreductase [General function    prediction only]; Region: COG3011
929556004484	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
929556004485	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
929556004486	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929556004487	ATP binding site [chemical binding]; other site
929556004488	putative Mg++ binding site [ion binding]; other site
929556004489	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929556004490	nucleotide binding region [chemical binding]; other site
929556004491	ATP-binding site [chemical binding]; other site
929556004492	RQC domain; Region: RQC; pfam09382
929556004493	HRDC domain; Region: HRDC; pfam00570
929556004494	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
929556004495	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
929556004496	putative active site [active]
929556004497	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
929556004498	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
929556004499	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
929556004500	Substrate binding site; other site
929556004501	Cupin domain; Region: Cupin_2; cl17218
929556004502	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
929556004503	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
929556004504	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
929556004505	replicative DNA helicase; Region: DnaB; TIGR00665
929556004506	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
929556004507	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
929556004508	Walker A motif; other site
929556004509	ATP binding site [chemical binding]; other site
929556004510	Walker B motif; other site
929556004511	DNA binding loops [nucleotide binding]
929556004512	Chromate transporter; Region: Chromate_transp; pfam02417
929556004513	chromate transporter, chromate ion transporter (CHR) family; Region: 2A51; TIGR00937
929556004514	Chromate transporter; Region: Chromate_transp; pfam02417
929556004515	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556004516	TPR motif; other site
929556004517	TPR repeat; Region: TPR_11; pfam13414
929556004518	binding surface
929556004519	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
929556004520	Ligand binding site [chemical binding]; other site
929556004521	Electron transfer flavoprotein domain; Region: ETF; pfam01012
929556004522	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
929556004523	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
929556004524	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
929556004525	Bifunctional nuclease; Region: DNase-RNase; pfam02577
929556004526	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
929556004527	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
929556004528	Nucleoside recognition; Region: Gate; pfam07670
929556004529	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
929556004530	Protein of unknown function (DUF3667); Region: DUF3667; pfam12412
929556004531	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
929556004532	dimer interface [polypeptide binding]; other site
929556004533	Citrate synthase; Region: Citrate_synt; pfam00285
929556004534	active site
929556004535	citrylCoA binding site [chemical binding]; other site
929556004536	NADH binding [chemical binding]; other site
929556004537	cationic pore residues; other site
929556004538	oxalacetate/citrate binding site [chemical binding]; other site
929556004539	coenzyme A binding site [chemical binding]; other site
929556004540	catalytic triad [active]
929556004541	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
929556004542	active site
929556004543	catalytic residues [active]
929556004544	Mitochondrial biogenesis AIM24; Region: AIM24; pfam01987
929556004545	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
929556004546	iron-sulfur cluster [ion binding]; other site
929556004547	[2Fe-2S] cluster binding site [ion binding]; other site
929556004548	Uncharacterized protein conserved in bacteria (DUF2219); Region: DUF2219; pfam09982
929556004549	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
929556004550	Histidine kinase; Region: HisKA_3; pfam07730
929556004551	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556004552	ATP binding site [chemical binding]; other site
929556004553	Mg2+ binding site [ion binding]; other site
929556004554	G-X-G motif; other site
929556004555	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
929556004556	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556004557	active site
929556004558	phosphorylation site [posttranslational modification]
929556004559	intermolecular recognition site; other site
929556004560	dimerization interface [polypeptide binding]; other site
929556004561	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
929556004562	DNA binding residues [nucleotide binding]
929556004563	dimerization interface [polypeptide binding]; other site
929556004564	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
929556004565	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
929556004566	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; cl01768
929556004567	Surface antigen; Region: Bac_surface_Ag; pfam01103
929556004568	Uncharacterized conserved protein [Function unknown]; Region: COG5361
929556004569	Protein of unknown function (DUF1254); Region: DUF1254; pfam06863
929556004570	Protein of unknown function (DUF1214); Region: DUF1214; cl08447
929556004571	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
929556004572	A new structural DNA glycosylase; Region: AlkD_like; cd06561
929556004573	active site
929556004574	Uncharacterized conserved protein [Function unknown]; Region: COG5361
929556004575	Protein of unknown function (DUF1254); Region: DUF1254; pfam06863
929556004576	Protein of unknown function (DUF1214); Region: DUF1214; pfam06742
929556004577	Uncharacterized conserved protein [Function unknown]; Region: COG5361
929556004578	Protein of unknown function (DUF1254); Region: DUF1254; pfam06863
929556004579	Protein of unknown function (DUF1214); Region: DUF1214; pfam06742
929556004580	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
929556004581	Sulfatase; Region: Sulfatase; pfam00884
929556004582	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
929556004583	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
929556004584	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
929556004585	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
929556004586	Sulfatase; Region: Sulfatase; pfam00884
929556004587	Sulfatase; Region: Sulfatase; cl17466
929556004588	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
929556004589	Protein of unknown function DUF58; Region: DUF58; pfam01882
929556004590	Domain of unknown function (DUF4381); Region: DUF4381; pfam14316
929556004591	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
929556004592	metal ion-dependent adhesion site (MIDAS); other site
929556004593	von Willebrand factor type A domain; Region: VWA_2; pfam13519
929556004594	metal ion-dependent adhesion site (MIDAS); other site
929556004595	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556004596	binding surface
929556004597	TPR repeat; Region: TPR_11; pfam13414
929556004598	TPR motif; other site
929556004599	Oxygen tolerance; Region: BatD; pfam13584
929556004600	MoxR-like ATPases [General function prediction only]; Region: COG0714
929556004601	ATPase family associated with various cellular activities (AAA); Region: AAA_3; pfam07726
929556004602	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2989
929556004603	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
929556004604	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
929556004605	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
929556004606	Protein of unknown function (DUF1634); Region: DUF1634; pfam07843
929556004607	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
929556004608	Surface antigen; Region: Bac_surface_Ag; pfam01103
929556004609	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
929556004610	putative hydrophobic ligand binding site [chemical binding]; other site
929556004611	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
929556004612	Sulfatase; Region: Sulfatase; pfam00884
929556004613	Domain of unknown function (DUF1508); Region: DUF1508; cl01356
929556004614	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
929556004615	Protein of unknown function (DUF3037); Region: DUF3037; pfam11236
929556004616	HipA-like N-terminal domain; Region: HipA_N; pfam07805
929556004617	HipA-like C-terminal domain; Region: HipA_C; pfam07804
929556004618	HipA N-terminal domain; Region: Couple_hipA; pfam13657
929556004619	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929556004620	non-specific DNA binding site [nucleotide binding]; other site
929556004621	salt bridge; other site
929556004622	sequence-specific DNA binding site [nucleotide binding]; other site
929556004623	Domain of unknown function (DUF4172); Region: DUF4172; pfam13776
929556004624	Fic family protein [Function unknown]; Region: COG3177
929556004625	Fic/DOC family; Region: Fic; pfam02661
929556004626	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
929556004627	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
929556004628	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
929556004629	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
929556004630	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929556004631	ATP binding site [chemical binding]; other site
929556004632	putative Mg++ binding site [ion binding]; other site
929556004633	Virulence protein [General function prediction only]; Region: COG3943
929556004634	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
929556004635	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
929556004636	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
929556004637	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
929556004638	S23 ribosomal protein; Region: Ribosomal_S23p; cl05287
929556004639	four helix bundle protein; Region: TIGR02436
929556004640	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
929556004641	HsdM N-terminal domain; Region: HsdM_N; pfam12161
929556004642	Methyltransferase domain; Region: Methyltransf_26; pfam13659
929556004643	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929556004644	non-specific DNA binding site [nucleotide binding]; other site
929556004645	salt bridge; other site
929556004646	sequence-specific DNA binding site [nucleotide binding]; other site
929556004647	mobile mystery protein A; Region: mob_myst_A; TIGR02612
929556004648	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929556004649	non-specific DNA binding site [nucleotide binding]; other site
929556004650	salt bridge; other site
929556004651	sequence-specific DNA binding site [nucleotide binding]; other site
929556004652	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
929556004653	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
929556004654	trmE is a tRNA modification GTPase; Region: trmE; cd04164
929556004655	G1 box; other site
929556004656	GTP/Mg2+ binding site [chemical binding]; other site
929556004657	Switch I region; other site
929556004658	G2 box; other site
929556004659	Switch II region; other site
929556004660	G3 box; other site
929556004661	G4 box; other site
929556004662	G5 box; other site
929556004663	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
929556004664	Domain of unknown function (DUF1905); Region: DUF1905; pfam08922
929556004665	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
929556004666	Protein of unknown function (DUF2400); Region: DUF2400; pfam09674
929556004667	YbaB/EbfC DNA-binding family; Region: YbaB_DNA_bd; pfam02575
929556004668	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
929556004669	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
929556004670	homodimer interface [polypeptide binding]; other site
929556004671	substrate-cofactor binding pocket; other site
929556004672	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556004673	catalytic residue [active]
929556004674	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556004675	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556004676	ligand binding site [chemical binding]; other site
929556004677	flexible hinge region; other site
929556004678	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
929556004679	putative switch regulator; other site
929556004680	non-specific DNA interactions [nucleotide binding]; other site
929556004681	DNA binding site [nucleotide binding]
929556004682	sequence specific DNA binding site [nucleotide binding]; other site
929556004683	putative cAMP binding site [chemical binding]; other site
929556004684	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
929556004685	trimer interface [polypeptide binding]; other site
929556004686	dimer interface [polypeptide binding]; other site
929556004687	putative active site [active]
929556004688	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
929556004689	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
929556004690	GTP binding site; other site
929556004691	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
929556004692	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
929556004693	Rubredoxin; Region: Rubredoxin; pfam00301
929556004694	iron binding site [ion binding]; other site
929556004695	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
929556004696	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
929556004697	molybdopterin cofactor binding site; other site
929556004698	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
929556004699	molybdopterin cofactor binding site; other site
929556004700	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
929556004701	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929556004702	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
929556004703	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556004704	putative substrate translocation pore; other site
929556004705	Domain of unknown function (DUF4104); Region: DUF4104; pfam13372
929556004706	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
929556004707	nitrite reductase subunit NirD; Provisional; Region: PRK14989
929556004708	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929556004709	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
929556004710	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
929556004711	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
929556004712	active site
929556004713	SAM binding site [chemical binding]; other site
929556004714	homodimer interface [polypeptide binding]; other site
929556004715	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
929556004716	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
929556004717	dimer interface [polypeptide binding]; other site
929556004718	putative functional site; other site
929556004719	putative MPT binding site; other site
929556004720	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
929556004721	MoaE homodimer interface [polypeptide binding]; other site
929556004722	MoaD interaction [polypeptide binding]; other site
929556004723	active site residues [active]
929556004724	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
929556004725	MoaE interaction surface [polypeptide binding]; other site
929556004726	MoeB interaction surface [polypeptide binding]; other site
929556004727	thiocarboxylated glycine; other site
929556004728	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
929556004729	molybdopterin biosynthesis-like protein MoeZ; Validated; Region: PRK07878
929556004730	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
929556004731	ATP binding site [chemical binding]; other site
929556004732	substrate interface [chemical binding]; other site
929556004733	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
929556004734	active site residue [active]
929556004735	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
929556004736	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
929556004737	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556004738	putative substrate translocation pore; other site
929556004739	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
929556004740	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
929556004741	[4Fe-4S] binding site [ion binding]; other site
929556004742	molybdopterin cofactor binding site; other site
929556004743	This CD includes formate dehydrogenases (Fdh) H and N; nitrate reductases, Nap and Nas; and other related proteins. Formate dehydrogenase H is a component of the anaerobic formate hydrogen lyase complex  and catalyzes the reversible oxidation of formate...; Region: MopB_CT_Fdh-Nap-like; cd00508
929556004744	molybdopterin cofactor binding site; other site
929556004745	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
929556004746	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cd03467
929556004747	iron-sulfur cluster [ion binding]; other site
929556004748	[2Fe-2S] cluster binding site [ion binding]; other site
929556004749	molybdenum cofactor biosynthesis protein A, bacterial; Region: moaA; TIGR02666
929556004750	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929556004751	FeS/SAM binding site; other site
929556004752	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
929556004753	prolyl-tRNA synthetase; Provisional; Region: PRK08661
929556004754	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
929556004755	dimer interface [polypeptide binding]; other site
929556004756	motif 1; other site
929556004757	active site
929556004758	motif 2; other site
929556004759	motif 3; other site
929556004760	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
929556004761	anticodon binding site; other site
929556004762	zinc-binding site [ion binding]; other site
929556004763	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
929556004764	menaquinone biosynthesis decarboxylase, SCO4490 family; Region: mena_SCO4490; TIGR03701
929556004765	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
929556004766	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_1; cd07818
929556004767	putative hydrophobic ligand binding site [chemical binding]; other site
929556004768	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
929556004769	Fatty acid desaturase; Region: FA_desaturase; pfam00487
929556004770	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
929556004771	putative di-iron ligands [ion binding]; other site
929556004772	Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030
929556004773	Nodulation formation efficiency D (NfeD) is a membrane-bound ClpP-class protease; Region: Clp_protease_NfeD_like; cd07021
929556004774	dimer interface [polypeptide binding]; other site
929556004775	active site residues [active]
929556004776	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
929556004777	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
929556004778	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
929556004779	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
929556004780	active site
929556004781	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
929556004782	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
929556004783	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
929556004784	glutaminase; Provisional; Region: PRK00971
929556004785	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
929556004786	MutS domain III; Region: MutS_III; pfam05192
929556004787	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556004788	Walker A/P-loop; other site
929556004789	ATP binding site [chemical binding]; other site
929556004790	Q-loop/lid; other site
929556004791	ABC transporter signature motif; other site
929556004792	Walker B; other site
929556004793	D-loop; other site
929556004794	H-loop/switch region; other site
929556004795	Smr domain; Region: Smr; pfam01713
929556004796	Domain of unknown function (DUF4296); Region: DUF4296; pfam14129
929556004797	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
929556004798	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
929556004799	catalytic residue [active]
929556004800	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
929556004801	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556004802	Coenzyme A binding pocket [chemical binding]; other site
929556004803	Aspartokinases [Amino acid transport and metabolism]; Region: LysC; COG0527
929556004804	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
929556004805	nucleotide binding site [chemical binding]; other site
929556004806	substrate binding site [chemical binding]; other site
929556004807	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
929556004808	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
929556004809	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
929556004810	23S rRNA binding site [nucleotide binding]; other site
929556004811	L21 binding site [polypeptide binding]; other site
929556004812	L13 binding site [polypeptide binding]; other site
929556004813	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
929556004814	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
929556004815	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
929556004816	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
929556004817	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
929556004818	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
929556004819	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
929556004820	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
929556004821	active site
929556004822	dimer interface [polypeptide binding]; other site
929556004823	motif 1; other site
929556004824	motif 2; other site
929556004825	motif 3; other site
929556004826	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
929556004827	anticodon binding site; other site
929556004828	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
929556004829	PAS fold; Region: PAS_3; pfam08447
929556004830	putative active site [active]
929556004831	heme pocket [chemical binding]; other site
929556004832	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
929556004833	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
929556004834	putative active site [active]
929556004835	heme pocket [chemical binding]; other site
929556004836	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556004837	dimer interface [polypeptide binding]; other site
929556004838	phosphorylation site [posttranslational modification]
929556004839	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556004840	ATP binding site [chemical binding]; other site
929556004841	Mg2+ binding site [ion binding]; other site
929556004842	G-X-G motif; other site
929556004843	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
929556004844	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556004845	active site
929556004846	phosphorylation site [posttranslational modification]
929556004847	intermolecular recognition site; other site
929556004848	dimerization interface [polypeptide binding]; other site
929556004849	Predicted membrane protein [Function unknown]; Region: COG2259
929556004850	CoB--CoM heterodisulfide reductase, subunit B; Region: CoB_CoM_SS_B; TIGR03288
929556004851	Cysteine-rich domain; Region: CCG; pfam02754
929556004852	Cysteine-rich domain; Region: CCG; pfam02754
929556004853	Vacuole effluxer Atg22 like; Region: ATG22; pfam11700
929556004854	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556004855	putative substrate translocation pore; other site
929556004856	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
929556004857	aspartate-alanine antiporter; Region: Asp_Ala_antiprt; TIGR03802
929556004858	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
929556004859	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
929556004860	aspartate 4-decarboxylase; Region: asp_4_decarbox; TIGR03801
929556004861	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
929556004862	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556004863	homodimer interface [polypeptide binding]; other site
929556004864	catalytic residue [active]
929556004865	VWA domain containing CoxE-like protein; Region: VWA_CoxE; pfam05762
929556004866	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
929556004867	metal ion-dependent adhesion site (MIDAS); other site
929556004868	MoxR-like ATPases [General function prediction only]; Region: COG0714
929556004869	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556004870	Walker A motif; other site
929556004871	ATP binding site [chemical binding]; other site
929556004872	Walker B motif; other site
929556004873	arginine finger; other site
929556004874	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
929556004875	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
929556004876	DEAD-like helicases superfamily; Region: DEXDc; smart00487
929556004877	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929556004878	ATP binding site [chemical binding]; other site
929556004879	putative Mg++ binding site [ion binding]; other site
929556004880	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929556004881	nucleotide binding region [chemical binding]; other site
929556004882	ATP-binding site [chemical binding]; other site
929556004883	Fructosamine kinase; Region: Fructosamin_kin; cl17579
929556004884	Phosphotransferase enzyme family; Region: APH; pfam01636
929556004885	putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional; Region: PRK14501
929556004886	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
929556004887	active site
929556004888	homotetramer interface [polypeptide binding]; other site
929556004889	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187; cl17105
929556004890	Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: SGA1; COG3387
929556004891	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
929556004892	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556004893	Major Facilitator Superfamily; Region: MFS_1; pfam07690
929556004894	putative substrate translocation pore; other site
929556004895	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
929556004896	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
929556004897	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
929556004898	Transglutaminase/protease-like homologues; Region: TGc; smart00460
929556004899	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
929556004900	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
929556004901	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
929556004902	putative DNA binding site [nucleotide binding]; other site
929556004903	putative Zn2+ binding site [ion binding]; other site
929556004904	AsnC family; Region: AsnC_trans_reg; pfam01037
929556004905	histidine decarboxylase; Provisional; Region: PRK02769
929556004906	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929556004907	catalytic residue [active]
929556004908	Mechanosensitive ion channel; Region: MS_channel; pfam00924
929556004909	Protein of unknown function (DUF1684); Region: DUF1684; pfam07920
929556004910	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
929556004911	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
929556004912	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
929556004913	active site
929556004914	HIGH motif; other site
929556004915	nucleotide binding site [chemical binding]; other site
929556004916	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
929556004917	KMSK motif region; other site
929556004918	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
929556004919	tRNA binding surface [nucleotide binding]; other site
929556004920	anticodon binding site; other site
929556004921	Amidinotransferase; Region: Amidinotransf; cl12043
929556004922	Uncharacterized protein conserved in bacteria containing a pentein-type domain [Function unknown]; Region: COG4874
929556004923	Amidinotransferase; Region: Amidinotransf; pfam02274
929556004924	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
929556004925	dimer interface [polypeptide binding]; other site
929556004926	active site
929556004927	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
929556004928	catalytic residues [active]
929556004929	substrate binding site [chemical binding]; other site
929556004930	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
929556004931	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
929556004932	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
929556004933	active site
929556004934	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556004935	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556004936	dimer interface [polypeptide binding]; other site
929556004937	phosphorylation site [posttranslational modification]
929556004938	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556004939	ATP binding site [chemical binding]; other site
929556004940	Mg2+ binding site [ion binding]; other site
929556004941	G-X-G motif; other site
929556004942	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929556004943	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556004944	active site
929556004945	phosphorylation site [posttranslational modification]
929556004946	intermolecular recognition site; other site
929556004947	dimerization interface [polypeptide binding]; other site
929556004948	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929556004949	DNA binding site [nucleotide binding]
929556004950	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
929556004951	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556004952	catalytic residues [active]
929556004953	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
929556004954	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
929556004955	GatB domain; Region: GatB_Yqey; smart00845
929556004956	Prokaryotic diacylglycerol kinase; Region: DAGK_prokar; pfam01219
929556004957	META domain; Region: META; pfam03724
929556004958	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
929556004959	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
929556004960	motif 1; other site
929556004961	active site
929556004962	motif 2; other site
929556004963	motif 3; other site
929556004964	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
929556004965	DHHA1 domain; Region: DHHA1; pfam02272
929556004966	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
929556004967	adenosylmethionine-8-amino-7-oxononanoate transaminase; Region: bioA; TIGR00508
929556004968	inhibitor-cofactor binding pocket; inhibition site
929556004969	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556004970	catalytic residue [active]
929556004971	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
929556004972	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
929556004973	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
929556004974	substrate binding site [chemical binding]; other site
929556004975	oxyanion hole (OAH) forming residues; other site
929556004976	trimer interface [polypeptide binding]; other site
929556004977	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
929556004978	Competence protein; Region: Competence; pfam03772
929556004979	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
929556004980	putative active site [active]
929556004981	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
929556004982	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
929556004983	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
929556004984	DNA binding residues [nucleotide binding]
929556004985	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
929556004986	Peptidase family M23; Region: Peptidase_M23; pfam01551
929556004987	D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429
929556004988	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
929556004989	nudix motif; other site
929556004990	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
929556004991	Cation efflux family; Region: Cation_efflux; pfam01545
929556004992	aspartate aminotransferase; Provisional; Region: PRK05764
929556004993	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
929556004994	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556004995	homodimer interface [polypeptide binding]; other site
929556004996	catalytic residue [active]
929556004997	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
929556004998	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
929556004999	putative ribose interaction site [chemical binding]; other site
929556005000	putative ADP binding site [chemical binding]; other site
929556005001	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556005002	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
929556005003	FtsX-like permease family; Region: FtsX; pfam02687
929556005004	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
929556005005	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
929556005006	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
929556005007	substrate binding site; other site
929556005008	dimer interface; other site
929556005009	Protein of unknown function (DUF2795); Region: DUF2795; pfam11387
929556005010	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
929556005011	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
929556005012	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
929556005013	Walker A/P-loop; other site
929556005014	ATP binding site [chemical binding]; other site
929556005015	Q-loop/lid; other site
929556005016	ABC transporter signature motif; other site
929556005017	Walker B; other site
929556005018	D-loop; other site
929556005019	H-loop/switch region; other site
929556005020	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
929556005021	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
929556005022	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
929556005023	putative acyl-acceptor binding pocket; other site
929556005024	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
929556005025	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
929556005026	active site
929556005027	HIGH motif; other site
929556005028	dimer interface [polypeptide binding]; other site
929556005029	KMSKS motif; other site
929556005030	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
929556005031	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
929556005032	Substrate-binding site [chemical binding]; other site
929556005033	Substrate specificity [chemical binding]; other site
929556005034	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
929556005035	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
929556005036	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
929556005037	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
929556005038	Helix-turn-helix domain; Region: HTH_18; pfam12833
929556005039	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556005040	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
929556005041	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929556005042	NAD(P) binding site [chemical binding]; other site
929556005043	active site
929556005044	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
929556005045	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
929556005046	Ligand binding site; other site
929556005047	oligomer interface; other site
929556005048	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
929556005049	Cysteine-rich CWC; Region: Cys_rich_CWC; pfam14375
929556005050	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
929556005051	PAS domain; Region: PAS_9; pfam13426
929556005052	putative active site [active]
929556005053	heme pocket [chemical binding]; other site
929556005054	CTP synthetase; Validated; Region: pyrG; PRK05380
929556005055	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
929556005056	Catalytic site [active]
929556005057	active site
929556005058	UTP binding site [chemical binding]; other site
929556005059	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
929556005060	active site
929556005061	putative oxyanion hole; other site
929556005062	catalytic triad [active]
929556005063	membrane protein insertase; Provisional; Region: PRK01318
929556005064	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
929556005065	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
929556005066	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
929556005067	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
929556005068	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
929556005069	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
929556005070	active site
929556005071	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
929556005072	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme D-Threonine Aldolase; Region: PLPDE_III_D-TA; cd06821
929556005073	Predicted amino acid aldolase or racemase [Amino acid transport and metabolism]; Region: COG3616
929556005074	dimer interface [polypeptide binding]; other site
929556005075	active site
929556005076	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
929556005077	substrate binding site [chemical binding]; other site
929556005078	catalytic residue [active]
929556005079	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
929556005080	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
929556005081	active site
929556005082	intersubunit interface [polypeptide binding]; other site
929556005083	catalytic residue [active]
929556005084	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
929556005085	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
929556005086	substrate binding site [chemical binding]; other site
929556005087	ATP binding site [chemical binding]; other site
929556005088	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_1; cd02199
929556005089	homotrimer interaction site [polypeptide binding]; other site
929556005090	putative active site [active]
929556005091	fructuronate transporter; Provisional; Region: PRK10034; cl15264
929556005092	GntP family permease; Region: GntP_permease; pfam02447
929556005093	Domain of unknown function (DU1801); Region: DUF1801; cl17490
929556005094	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
929556005095	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
929556005096	minor groove reading motif; other site
929556005097	helix-hairpin-helix signature motif; other site
929556005098	active site
929556005099	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
929556005100	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
929556005101	active site residue [active]
929556005102	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
929556005103	active site residue [active]
929556005104	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
929556005105	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
929556005106	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556005107	Coenzyme A binding pocket [chemical binding]; other site
929556005108	Uncharacterized protein conserved in bacteria (DUF2199); Region: DUF2199; cl02048
929556005109	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556005110	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
929556005111	active site
929556005112	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
929556005113	active site
929556005114	catalytic site [active]
929556005115	substrate binding site [chemical binding]; other site
929556005116	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
929556005117	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
929556005118	Insecticide toxin TcdB middle/N-terminal region; Region: TcdB_toxin_midN; pfam12256
929556005119	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
929556005120	RHS Repeat; Region: RHS_repeat; cl11982
929556005121	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556005122	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556005123	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
929556005124	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
929556005125	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556005126	Walker A motif; other site
929556005127	ATP binding site [chemical binding]; other site
929556005128	Walker B motif; other site
929556005129	arginine finger; other site
929556005130	Domain of unknown function (DUF4157); Region: DUF4157; pfam13699
929556005131	Predicted membrane protein [Function unknown]; Region: COG3817
929556005132	DNA binding domain, excisionase family; Region: excise; TIGR01764
929556005133	PIN domain; Region: PIN_3; pfam13470
929556005134	Domain of unknown function (DUF4157); Region: DUF4157; pfam13699
929556005135	Domain of unknown function (DUF4157); Region: DUF4157; pfam13699
929556005136	OmpA family; Region: OmpA; pfam00691
929556005137	ligand binding site [chemical binding]; other site
929556005138	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556005139	ligand binding site [chemical binding]; other site
929556005140	Domain of unknown function (DUF4157); Region: DUF4157; pfam13699
929556005141	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
929556005142	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
929556005143	conserved hypothetical protein, phage tail-like region; Region: TIGR02243
929556005144	conserved hypothetical protein, phage tail-like region; Region: TIGR02243
929556005145	Gene 25-like lysozyme; Region: GPW_gp25; pfam04965
929556005146	PAAR motif; Region: PAAR_motif; pfam05488
929556005147	Phage protein D [General function prediction only]; Region: COG3500
929556005148	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
929556005149	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
929556005150	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841
929556005151	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841
929556005152	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
929556005153	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
929556005154	Protein of unknown function (DUF4255); Region: DUF4255; pfam14065
929556005155	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: PhosphMutase; cl17294
929556005156	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
929556005157	PAS fold; Region: PAS_3; pfam08447
929556005158	putative active site [active]
929556005159	heme pocket [chemical binding]; other site
929556005160	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK08270
929556005161	ATP cone domain; Region: ATP-cone; pfam03477
929556005162	Class III ribonucleotide reductase; Region: RNR_III; cd01675
929556005163	effector binding site; other site
929556005164	active site
929556005165	Zn binding site [ion binding]; other site
929556005166	Anaerobic ribonucleoside-triphosphate reductase; Region: NRDD; pfam13597
929556005167	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG2; TIGR02495
929556005168	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929556005169	FeS/SAM binding site; other site
929556005170	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
929556005171	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
929556005172	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
929556005173	EamA-like transporter family; Region: EamA; pfam00892
929556005174	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
929556005175	EamA-like transporter family; Region: EamA; pfam00892
929556005176	Transposase; Region: HTH_Tnp_1; pfam01527
929556005177	Secretin and TonB N terminus short domain; Region: STN; pfam07660
929556005178	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556005179	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556005180	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556005181	FecR protein; Region: FecR; pfam04773
929556005182	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
929556005183	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556005184	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556005185	DNA binding residues [nucleotide binding]
929556005186	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
929556005187	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556005188	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556005189	DNA binding residues [nucleotide binding]
929556005190	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
929556005191	C-terminal processing peptidase-like; serine protease family S41; Region: Peptidase_S41_CPP_like; cd07561
929556005192	Catalytic dyad [active]
929556005193	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556005194	TonB-dependent receptor; Region: TonB-Xanth-Caul; TIGR01782
929556005195	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556005196	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556005197	FecR protein; Region: FecR; pfam04773
929556005198	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
929556005199	oxidoreductase; Provisional; Region: PRK06196
929556005200	retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs; Region: retinol-DH_like_SDR_c_like; cd05327
929556005201	putative NAD(P) binding site [chemical binding]; other site
929556005202	active site
929556005203	Helix-turn-helix domain; Region: HTH_18; pfam12833
929556005204	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556005205	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
929556005206	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
929556005207	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
929556005208	Uncharacterized protein conserved in bacteria N-term (DUF3322); Region: DUF3322; pfam11795
929556005209	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4924
929556005210	Uncharacterized protein conserved in bacteria C-term(DUF2220); Region: DUF2220; pfam09983
929556005211	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4913
929556005212	P-loop containing region of AAA domain; Region: AAA_29; pfam13555
929556005213	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
929556005214	Domain of unknown function (DUF4194); Region: DUF4194; pfam13835
929556005215	Protein of unknown function (DUF3375); Region: DUF3375; pfam11855
929556005216	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
929556005217	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
929556005218	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
929556005219	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
929556005220	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556005221	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
929556005222	protein-splicing catalytic site; other site
929556005223	thioester formation/cholesterol transfer; other site
929556005224	Pretoxin HINT domain; Region: PT-HINT; pfam07591
929556005225	Helix-turn-helix domain; Region: HTH_17; pfam12728
929556005226	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
929556005227	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
929556005228	active site
929556005229	DNA binding site [nucleotide binding]
929556005230	Int/Topo IB signature motif; other site
929556005231	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
929556005232	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
929556005233	catalytic residues [active]
929556005234	catalytic nucleophile [active]
929556005235	Recombinase; Region: Recombinase; pfam07508
929556005236	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
929556005237	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
929556005238	Transposase; Region: DDE_Tnp_ISL3; pfam01610
929556005239	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
929556005240	RNA/DNA hybrid binding site [nucleotide binding]; other site
929556005241	active site
929556005242	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
929556005243	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
929556005244	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556005245	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
929556005246	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
929556005247	N-terminal plug; other site
929556005248	ligand-binding site [chemical binding]; other site
929556005249	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
929556005250	Putative catalytic NodB homology domain of uncharacterized bacterial polysaccharide deacetylases which consist of a 5-stranded beta/alpha barrel; Region: CE4_DAC_u3_5s; cd10972
929556005251	putative active site [active]
929556005252	putative metal binding site [ion binding]; other site
929556005253	Domain of unknown function (DUF1905); Region: DUF1905; pfam08922
929556005254	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
929556005255	NlpC/P60 family; Region: NLPC_P60; pfam00877
929556005256	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
929556005257	Protein of unknown function (DUF3575); Region: DUF3575; pfam12099
929556005258	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
929556005259	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
929556005260	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556005261	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556005262	DNA binding residues [nucleotide binding]
929556005263	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
929556005264	FecR protein; Region: FecR; pfam04773
929556005265	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556005266	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3787; cl17897
929556005267	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_3; cd07820
929556005268	putative hydrophobic ligand binding site [chemical binding]; other site
929556005269	YceI-like domain; Region: YceI; pfam04264
929556005270	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
929556005271	4Fe-4S binding domain; Region: Fer4; cl02805
929556005272	Polysulphide reductase [Energy production and conversion]; Region: COG5557; cl17901
929556005273	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
929556005274	Protein of unknown function (DUF2505); Region: DUF2505; pfam10698
929556005275	Cytochrome c; Region: Cytochrom_C; pfam00034
929556005276	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
929556005277	MutS domain I; Region: MutS_I; pfam01624
929556005278	MutS domain II; Region: MutS_II; pfam05188
929556005279	MutS domain III; Region: MutS_III; pfam05192
929556005280	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556005281	Walker A/P-loop; other site
929556005282	ATP binding site [chemical binding]; other site
929556005283	Q-loop/lid; other site
929556005284	ABC transporter signature motif; other site
929556005285	Walker B; other site
929556005286	D-loop; other site
929556005287	H-loop/switch region; other site
929556005288	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
929556005289	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
929556005290	putative active site [active]
929556005291	metal binding site [ion binding]; metal-binding site
929556005292	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
929556005293	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
929556005294	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
929556005295	active site
929556005296	intersubunit interactions; other site
929556005297	catalytic residue [active]
929556005298	Protein of unknown function (DUF3810); Region: DUF3810; pfam12725
929556005299	histidinol-phosphate phosphatase family domain; Region: Histidinol-ppas; TIGR01656
929556005300	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929556005301	active site
929556005302	motif I; other site
929556005303	motif II; other site
929556005304	OPT oligopeptide transporter protein; Region: OPT; cl14607
929556005305	putative oligopeptide transporter, OPT family; Region: TIGR00733
929556005306	Aspartate racemase [Cell envelope biogenesis, outer membrane]; Region: RacX; COG1794
929556005307	aspartate racemase; Region: asp_race; TIGR00035
929556005308	Homoserine dehydrogenase [Amino acid transport and metabolism]; Region: ThrA; COG0460
929556005309	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
929556005310	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
929556005311	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
929556005312	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
929556005313	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
929556005314	PspC domain; Region: PspC; cl00864
929556005315	Protein of unknown function (DUF2851); Region: DUF2851; pfam11013
929556005316	DinB superfamily; Region: DinB_2; pfam12867
929556005317	Mycothiol maleylpyruvate isomerase N-terminal domain; Region: MDMPI_N; pfam11716
929556005318	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
929556005319	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
929556005320	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556005321	Coenzyme A binding pocket [chemical binding]; other site
929556005322	Transcription factor zinc-finger; Region: zf-TFIIB; pfam13453
929556005323	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
929556005324	active site
929556005325	dimer interface [polypeptide binding]; other site
929556005326	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
929556005327	transcription termination factor Rho; Provisional; Region: rho; PRK09376
929556005328	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
929556005329	RNA binding site [nucleotide binding]; other site
929556005330	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
929556005331	multimer interface [polypeptide binding]; other site
929556005332	Walker A motif; other site
929556005333	ATP binding site [chemical binding]; other site
929556005334	Walker B motif; other site
929556005335	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
929556005336	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
929556005337	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; cl00789
929556005338	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
929556005339	catalytic center binding site [active]
929556005340	ATP binding site [chemical binding]; other site
929556005341	signal peptide peptidase SppA, 67K type; Region: SppA_67K; TIGR00705
929556005342	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
929556005343	tandem repeat interface [polypeptide binding]; other site
929556005344	oligomer interface [polypeptide binding]; other site
929556005345	active site residues [active]
929556005346	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
929556005347	tandem repeat interface [polypeptide binding]; other site
929556005348	oligomer interface [polypeptide binding]; other site
929556005349	active site residues [active]
929556005350	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
929556005351	hypothetical protein; Provisional; Region: PRK08609
929556005352	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
929556005353	metal binding triad [ion binding]; metal-binding site
929556005354	Polymerase and Histidinol Phosphatase domain of bacterial polymerase X; Region: PHP_PolX; cd07436
929556005355	active site
929556005356	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
929556005357	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
929556005358	putative active site [active]
929556005359	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
929556005360	catalytic core [active]
929556005361	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
929556005362	DNA protecting protein DprA; Region: dprA; TIGR00732
929556005363	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
929556005364	Methyltransferase domain; Region: Methyltransf_31; pfam13847
929556005365	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556005366	S-adenosylmethionine binding site [chemical binding]; other site
929556005367	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
929556005368	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556005369	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556005370	DNA binding residues [nucleotide binding]
929556005371	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
929556005372	active site
929556005373	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
929556005374	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
929556005375	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929556005376	non-specific DNA binding site [nucleotide binding]; other site
929556005377	salt bridge; other site
929556005378	sequence-specific DNA binding site [nucleotide binding]; other site
929556005379	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929556005380	non-specific DNA binding site [nucleotide binding]; other site
929556005381	salt bridge; other site
929556005382	sequence-specific DNA binding site [nucleotide binding]; other site
929556005383	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
929556005384	Predicted permeases [General function prediction only]; Region: COG0795
929556005385	EamA-like transporter family; Region: EamA; pfam00892
929556005386	Peptidase MA superfamily; Region: Peptidase_MA_2; pfam13485
929556005387	Predicted transcriptional regulator [Transcription]; Region: COG1959
929556005388	Transcriptional regulator; Region: Rrf2; pfam02082
929556005389	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648
929556005390	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
929556005391	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
929556005392	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
929556005393	active site
929556005394	SAM binding site [chemical binding]; other site
929556005395	homodimer interface [polypeptide binding]; other site
929556005396	Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Region: CysI; COG0155
929556005397	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
929556005398	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
929556005399	HEPN domain; Region: HEPN; cl00824
929556005400	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556005401	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
929556005402	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556005403	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
929556005404	Domain of unknown function (DUF4349); Region: DUF4349; pfam14257
929556005405	O-succinylhomoserine sulfhydrylase; Validated; Region: PRK08133
929556005406	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
929556005407	homodimer interface [polypeptide binding]; other site
929556005408	substrate-cofactor binding pocket; other site
929556005409	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556005410	catalytic residue [active]
929556005411	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
929556005412	GTPases - Sulfate adenylate transferase subunit 1 [Inorganic ion transport and metabolism]; Region: CysN; COG2895
929556005413	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
929556005414	CysD dimerization site [polypeptide binding]; other site
929556005415	G1 box; other site
929556005416	putative GEF interaction site [polypeptide binding]; other site
929556005417	GTP/Mg2+ binding site [chemical binding]; other site
929556005418	Switch I region; other site
929556005419	G2 box; other site
929556005420	G3 box; other site
929556005421	Switch II region; other site
929556005422	G4 box; other site
929556005423	G5 box; other site
929556005424	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
929556005425	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
929556005426	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
929556005427	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
929556005428	Active Sites [active]
929556005429	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
929556005430	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
929556005431	Active Sites [active]
929556005432	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
929556005433	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
929556005434	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK14609
929556005435	thymidylate synthase; Reviewed; Region: thyA; PRK01827
929556005436	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
929556005437	dimerization interface [polypeptide binding]; other site
929556005438	active site
929556005439	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
929556005440	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
929556005441	folate binding site [chemical binding]; other site
929556005442	NADP+ binding site [chemical binding]; other site
929556005443	Chagasin family peptidase inhibitor I42; Region: Inhibitor_I42; pfam09394
929556005444	Peptidase C1A subfamily (MEROPS database nomenclature); composed of cysteine peptidases (CPs) similar to papain, including the mammalian CPs (cathepsins B, C, F, H, L, K, O, S, V, X and W). Papain is an endopeptidase with specific substrate preferences; Region: Peptidase_C1A; cd02248
929556005445	active site
929556005446	S2 subsite; other site
929556005447	C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some...; Region: Peptidase_C1; cd02619
929556005448	active site
929556005449	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
929556005450	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
929556005451	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
929556005452	Protein export membrane protein; Region: SecD_SecF; pfam02355
929556005453	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
929556005454	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929556005455	3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain; Region: DRE_TIM_HMGL; cd07938
929556005456	active site
929556005457	catalytic residues [active]
929556005458	metal binding site [ion binding]; metal-binding site
929556005459	Transposase IS200 like; Region: Y1_Tnp; pfam01797
929556005460	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
929556005461	Alpha amylase catalytic domain found in archaeal and bacterial Alpha-amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_arch_bac_AmyA; cd11313
929556005462	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
929556005463	active site
929556005464	catalytic site [active]
929556005465	Cyclo-malto-dextrinase C-terminal domain; Region: Cyc-maltodext_C; pfam10438
929556005466	SusE outer membrane protein; Region: SusE; pfam14292
929556005467	Uncharacterized subgroup of the CBM-SusE-F_like superfamily; Region: CBM_SusE-F_like_u1; cd12967
929556005468	starch binding site [chemical binding]; other site
929556005469	carbohydrate-binding modules from Bacteroides thetaiotaomicron SusE, SusF and similar proteins; Region: CBM_SusE-F_like; cd12956
929556005470	starch binding site [chemical binding]; other site
929556005471	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556005472	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556005473	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556005474	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556005475	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556005476	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556005477	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
929556005478	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929556005479	active site
929556005480	motif I; other site
929556005481	motif II; other site
929556005482	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
929556005483	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
929556005484	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929556005485	Soluble P-type ATPase [General function prediction only]; Region: COG4087
929556005486	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
929556005487	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
929556005488	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
929556005489	putative active site; other site
929556005490	catalytic residue [active]
929556005491	Predicted membrane protein [Function unknown]; Region: COG2855
929556005492	Transcriptional regulator [Transcription]; Region: LysR; COG0583
929556005493	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
929556005494	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
929556005495	putative dimerization interface [polypeptide binding]; other site
929556005496	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
929556005497	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
929556005498	Autoinducer synthetase; Region: Autoind_synth; cl17404
929556005499	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
929556005500	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556005501	Coenzyme A binding pocket [chemical binding]; other site
929556005502	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556005503	Major Facilitator Superfamily; Region: MFS_1; pfam07690
929556005504	putative substrate translocation pore; other site
929556005505	Alpha amylase catalytic domain found in an uncharacterized protein family; Region: AmyAc_3; cd11349
929556005506	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
929556005507	active site
929556005508	catalytic site [active]
929556005509	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
929556005510	classical (c) SDRs; Region: SDR_c; cd05233
929556005511	NAD(P) binding site [chemical binding]; other site
929556005512	active site
929556005513	maltose phosphorylase; Provisional; Region: PRK13807
929556005514	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
929556005515	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
929556005516	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
929556005517	beta-phosphoglucomutase; Region: bPGM; TIGR01990
929556005518	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929556005519	Cyclomaltodextrinase, N-terminal; Region: Cyc-maltodext_N; pfam09087
929556005520	Alpha amylase catalytic domain found in bacterial cyclomaltodextrinases and related proteins; Region: AmyAc_bac_CMD_like_3; cd11340
929556005521	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
929556005522	Ca binding site [ion binding]; other site
929556005523	active site
929556005524	homodimer interface [polypeptide binding]; other site
929556005525	catalytic site [active]
929556005526	Cyclo-malto-dextrinase C-terminal domain; Region: Cyc-maltodext_C; pfam10438
929556005527	Uncharacterized protein family (UPF0150); Region: UPF0150; cl00691
929556005528	YcfA-like protein; Region: YcfA; pfam07927
929556005529	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
929556005530	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
929556005531	active site
929556005532	intersubunit interface [polypeptide binding]; other site
929556005533	zinc binding site [ion binding]; other site
929556005534	Na+ binding site [ion binding]; other site
929556005535	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
929556005536	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
929556005537	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
929556005538	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
929556005539	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929556005540	catalytic residue [active]
929556005541	phosphoglucosamine mutase; Region: Arch_GlmM; TIGR03990
929556005542	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
929556005543	active site
929556005544	substrate binding site [chemical binding]; other site
929556005545	metal binding site [ion binding]; metal-binding site
929556005546	Methyltransferase domain; Region: Methyltransf_23; pfam13489
929556005547	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556005548	S-adenosylmethionine binding site [chemical binding]; other site
929556005549	PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_4; cd03395
929556005550	active site
929556005551	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
929556005552	ZIP Zinc transporter; Region: Zip; pfam02535
929556005553	MarR family; Region: MarR_2; pfam12802
929556005554	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
929556005555	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556005556	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556005557	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556005558	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
929556005559	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556005560	putative exonuclease, DNA ligase-associated; Region: Xnuc_lig_assoc; TIGR04122
929556005561	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
929556005562	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
929556005563	CoA-binding site [chemical binding]; other site
929556005564	YbbR-like protein; Region: YbbR; pfam07949
929556005565	Preprotein translocase subunit; Region: YajC; pfam02699
929556005566	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
929556005567	transcription antitermination factor NusB; Region: nusB; TIGR01951
929556005568	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
929556005569	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Region: ELFV_dehydrog; pfam00208
929556005570	NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase; Region: NAD_bind_Leu_Phe_Val_DH; cd01075
929556005571	NAD binding site [chemical binding]; other site
929556005572	Phe binding site; other site
929556005573	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
929556005574	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
929556005575	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556005576	Walker A/P-loop; other site
929556005577	ATP binding site [chemical binding]; other site
929556005578	Q-loop/lid; other site
929556005579	ABC transporter signature motif; other site
929556005580	Walker B; other site
929556005581	D-loop; other site
929556005582	H-loop/switch region; other site
929556005583	Protein of unknown function (DUF3276); Region: DUF3276; pfam11680
929556005584	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929556005585	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929556005586	Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU)...; Region: Glycosylasparaginase; cd04513
929556005587	active site
929556005588	dimer interface [polypeptide binding]; other site
929556005589	catalytic nucleophile [active]
929556005590	GTP-binding protein YchF; Reviewed; Region: PRK09601
929556005591	YchF GTPase; Region: YchF; cd01900
929556005592	G1 box; other site
929556005593	GTP/Mg2+ binding site [chemical binding]; other site
929556005594	Switch I region; other site
929556005595	G2 box; other site
929556005596	Switch II region; other site
929556005597	G3 box; other site
929556005598	G4 box; other site
929556005599	G5 box; other site
929556005600	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
929556005601	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
929556005602	metal-binding site [ion binding]
929556005603	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
929556005604	metal-binding site [ion binding]
929556005605	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556005606	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
929556005607	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556005608	histidine decarboxylase; Provisional; Region: PRK02769
929556005609	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929556005610	catalytic residue [active]
929556005611	PhoD-like phosphatase; Region: PhoD; pfam09423
929556005612	Bacillus subtilis PhoD and related proteins, metallophosphatase domain; Region: MPP_PhoD; cd07389
929556005613	putative active site [active]
929556005614	putative metal binding site [ion binding]; other site
929556005615	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556005616	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556005617	ligand binding site [chemical binding]; other site
929556005618	flexible hinge region; other site
929556005619	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
929556005620	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556005621	Walker A/P-loop; other site
929556005622	ATP binding site [chemical binding]; other site
929556005623	Q-loop/lid; other site
929556005624	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929556005625	ABC transporter; Region: ABC_tran_2; pfam12848
929556005626	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929556005627	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
929556005628	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
929556005629	quinone interaction residues [chemical binding]; other site
929556005630	active site
929556005631	catalytic residues [active]
929556005632	FMN binding site [chemical binding]; other site
929556005633	substrate binding site [chemical binding]; other site
929556005634	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
929556005635	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
929556005636	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
929556005637	Surface antigen; Region: Bac_surface_Ag; pfam01103
929556005638	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
929556005639	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
929556005640	active site
929556005641	nucleophile elbow; other site
929556005642	Calx-beta domain; Region: Calx-beta; cl02522
929556005643	Calx-beta domain; Region: Calx-beta; cl02522
929556005644	Calx-beta domain; Region: Calx-beta; cl02522
929556005645	Calx-beta domain; Region: Calx-beta; pfam03160
929556005646	Calx-beta domain; Region: Calx-beta; pfam03160
929556005647	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556005648	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556005649	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556005650	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556005651	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556005652	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556005653	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556005654	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556005655	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556005656	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
929556005657	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556005658	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
929556005659	Calx-beta domain; Region: Calx-beta; cl02522
929556005660	Calx-beta domain; Region: Calx-beta; cl02522
929556005661	Calx-beta domain; Region: Calx-beta; cl02522
929556005662	Calx-beta domain; Region: Calx-beta; pfam03160
929556005663	Calx-beta domain; Region: Calx-beta; pfam03160
929556005664	Calx-beta domain; Region: Calx-beta; cl02522
929556005665	Calx-beta domain; Region: Calx-beta; cl02522
929556005666	Calx-beta domain; Region: Calx-beta; pfam03160
929556005667	Calx-beta domain; Region: Calx-beta; cl02522
929556005668	Calx-beta domain; Region: Calx-beta; pfam03160
929556005669	Calx-beta domain; Region: Calx-beta; pfam03160
929556005670	Calx-beta domain; Region: Calx-beta; cl02522
929556005671	Calx-beta domain; Region: Calx-beta; pfam03160
929556005672	Calx-beta domain; Region: Calx-beta; cl02522
929556005673	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556005674	Calx-beta domain; Region: Calx-beta; cl02522
929556005675	Calx-beta domain; Region: Calx-beta; cl02522
929556005676	Calx-beta domain; Region: Calx-beta; pfam03160
929556005677	Calx-beta domain; Region: Calx-beta; pfam03160
929556005678	Calx-beta domain; Region: Calx-beta; cl02522
929556005679	Calx-beta domain; Region: Calx-beta; pfam03160
929556005680	Calx-beta domain; Region: Calx-beta; cl02522
929556005681	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556005682	Calx-beta domain; Region: Calx-beta; cl02522
929556005683	Calx-beta domain; Region: Calx-beta; cl02522
929556005684	Calx-beta domain; Region: Calx-beta; pfam03160
929556005685	Calx-beta domain; Region: Calx-beta; pfam03160
929556005686	Calx-beta domain; Region: Calx-beta; cl02522
929556005687	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556005688	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
929556005689	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556005690	TPR motif; other site
929556005691	binding surface
929556005692	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556005693	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
929556005694	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556005695	ligand binding site [chemical binding]; other site
929556005696	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
929556005697	conserved repeat domain; Region: B_ant_repeat; TIGR01451
929556005698	conserved repeat domain; Region: B_ant_repeat; TIGR01451
929556005699	Domain of unknown function DUF11; Region: DUF11; cl17728
929556005700	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556005701	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
929556005702	EVE domain; Region: EVE; pfam01878
929556005703	C4-type Zn-finger protein [General function prediction only]; Region: COG1779
929556005704	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
929556005705	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
929556005706	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
929556005707	PQQ-like domain; Region: PQQ_2; pfam13360
929556005708	YWTD domain; Region: YWTD; pfam13570
929556005709	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
929556005710	Trp docking motif [polypeptide binding]; other site
929556005711	active site
929556005712	PQQ-like domain; Region: PQQ_2; pfam13360
929556005713	putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824
929556005714	PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276
929556005715	NAD(P) binding site [chemical binding]; other site
929556005716	potential frameshift: common BLAST hit: gi|338209807|ref|YP_004653854.1| Crp/Fnr family transcriptional regulator
929556005717	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556005718	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556005719	ligand binding site [chemical binding]; other site
929556005720	flexible hinge region; other site
929556005721	Major Facilitator Superfamily; Region: MFS_1; pfam07690
929556005722	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556005723	putative substrate translocation pore; other site
929556005724	HEAT repeats; Region: HEAT_2; pfam13646
929556005725	HEAT repeats; Region: HEAT_2; pfam13646
929556005726	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556005727	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556005728	Peptidase domain in the S53 family; Region: Peptidases_S53_like; cd05562
929556005729	putative active site [active]
929556005730	putative catalytic triad [active]
929556005731	Peptidase domain in the S53 family; Region: Peptidases_S53_like; cd05562
929556005732	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
929556005733	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556005734	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556005735	binding surface
929556005736	TPR motif; other site
929556005737	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556005738	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556005739	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556005740	binding surface
929556005741	TPR motif; other site
929556005742	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556005743	Adenylyl- / guanylyl cyclase, catalytic domain; Region: CYCc; smart00044
929556005744	cyclase homology domain; Region: CHD; cd07302
929556005745	nucleotidyl binding site; other site
929556005746	metal binding site [ion binding]; metal-binding site
929556005747	dimer interface [polypeptide binding]; other site
929556005748	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
929556005749	DNA polymerase III, delta subunit [DNA replication, recombination, and repair]; Region: HolA; COG1466
929556005750	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
929556005751	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N_2; pfam13588
929556005752	S-adenosylmethionine decarboxylase; Region: AdoMet_dc; pfam02675
929556005753	TPR repeat; Region: TPR_11; pfam13414
929556005754	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556005755	binding surface
929556005756	TPR motif; other site
929556005757	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556005758	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556005759	binding surface
929556005760	TPR motif; other site
929556005761	spermidine synthase; Provisional; Region: PRK03612
929556005762	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556005763	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
929556005764	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
929556005765	Beta-galactosidase jelly roll domain; Region: BetaGal_dom4_5; pfam13364
929556005766	NlpE N-terminal domain; Region: NlpE; pfam04170
929556005767	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
929556005768	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
929556005769	active site
929556005770	HIGH motif; other site
929556005771	nucleotide binding site [chemical binding]; other site
929556005772	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
929556005773	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
929556005774	active site
929556005775	KMSKS motif; other site
929556005776	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
929556005777	tRNA binding surface [nucleotide binding]; other site
929556005778	anticodon binding site; other site
929556005779	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
929556005780	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
929556005781	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556005782	S-adenosylmethionine binding site [chemical binding]; other site
929556005783	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556005784	Coenzyme A binding pocket [chemical binding]; other site
929556005785	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
929556005786	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
929556005787	homodimer interface [polypeptide binding]; other site
929556005788	metal binding site [ion binding]; metal-binding site
929556005789	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
929556005790	homodimer interface [polypeptide binding]; other site
929556005791	active site
929556005792	putative chemical substrate binding site [chemical binding]; other site
929556005793	metal binding site [ion binding]; metal-binding site
929556005794	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556005795	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556005796	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556005797	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556005798	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556005799	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556005800	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
929556005801	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
929556005802	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556005803	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
929556005804	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
929556005805	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556005806	catalytic residues [active]
929556005807	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
929556005808	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556005809	FtsX-like permease family; Region: FtsX; pfam02687
929556005810	DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; Region: DnaJ; COG0484
929556005811	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
929556005812	HSP70 interaction site [polypeptide binding]; other site
929556005813	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
929556005814	substrate binding site [polypeptide binding]; other site
929556005815	dimer interface [polypeptide binding]; other site
929556005816	DNA-damage-inducible protein D; Provisional; Region: dinD; PRK11525
929556005817	Glutamate synthase domain 2 [Amino acid transport and metabolism]; Region: GltB; COG0069
929556005818	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
929556005819	active site
929556005820	FMN binding site [chemical binding]; other site
929556005821	substrate binding site [chemical binding]; other site
929556005822	3Fe-4S cluster binding site [ion binding]; other site
929556005823	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
929556005824	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556005825	putative metal binding site [ion binding]; other site
929556005826	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
929556005827	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
929556005828	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
929556005829	putative active site [active]
929556005830	substrate binding site [chemical binding]; other site
929556005831	putative cosubstrate binding site; other site
929556005832	catalytic site [active]
929556005833	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
929556005834	substrate binding site [chemical binding]; other site
929556005835	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
929556005836	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
929556005837	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cd00449
929556005838	homodimer interface [polypeptide binding]; other site
929556005839	substrate-cofactor binding pocket; other site
929556005840	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556005841	catalytic residue [active]
929556005842	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
929556005843	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
929556005844	RNA binding surface [nucleotide binding]; other site
929556005845	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
929556005846	active site
929556005847	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
929556005848	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
929556005849	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929556005850	catalytic residue [active]
929556005851	L-lysine aminotransferase; Provisional; Region: PRK08297
929556005852	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
929556005853	inhibitor-cofactor binding pocket; inhibition site
929556005854	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556005855	catalytic residue [active]
929556005856	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
929556005857	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
929556005858	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
929556005859	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556005860	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
929556005861	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
929556005862	N-terminal plug; other site
929556005863	ligand-binding site [chemical binding]; other site
929556005864	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
929556005865	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
929556005866	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556005867	catalytic residues [active]
929556005868	bacillithiol biosynthesis deacetylase BshB1; Region: thiol_BshB1; TIGR04001
929556005869	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
929556005870	catalytic residues [active]
929556005871	dimer interface [polypeptide binding]; other site
929556005872	Domain of unknown function (DUF4294); Region: DUF4294; pfam14127
929556005873	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
929556005874	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929556005875	Zn2+ binding site [ion binding]; other site
929556005876	Mg2+ binding site [ion binding]; other site
929556005877	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
929556005878	synthetase active site [active]
929556005879	NTP binding site [chemical binding]; other site
929556005880	metal binding site [ion binding]; metal-binding site
929556005881	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
929556005882	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
929556005883	ferric uptake regulator; Provisional; Region: fur; PRK09462
929556005884	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
929556005885	metal binding site 2 [ion binding]; metal-binding site
929556005886	putative DNA binding helix; other site
929556005887	metal binding site 1 [ion binding]; metal-binding site
929556005888	dimer interface [polypeptide binding]; other site
929556005889	structural Zn2+ binding site [ion binding]; other site
929556005890	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
929556005891	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
929556005892	GDP-binding site [chemical binding]; other site
929556005893	ACT binding site; other site
929556005894	IMP binding site; other site
929556005895	aminodeoxychorismate synthase, component I, clade 2; Region: PabB-clade2; TIGR01824
929556005896	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
929556005897	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
929556005898	catalytic residues [active]
929556005899	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556005900	binding surface
929556005901	Tetratricopeptide repeat; Region: TPR_16; pfam13432
929556005902	TPR motif; other site
929556005903	Peptidase family M48; Region: Peptidase_M48; pfam01435
929556005904	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
929556005905	Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157
929556005906	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
929556005907	dimerization interface [polypeptide binding]; other site
929556005908	active site
929556005909	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
929556005910	phosphoglyceromutase; Provisional; Region: PRK05434
929556005911	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5368
929556005912	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
929556005913	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
929556005914	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
929556005915	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
929556005916	active site
929556005917	Methyltransferase domain; Region: Methyltransf_11; pfam08241
929556005918	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
929556005919	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
929556005920	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
929556005921	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
929556005922	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
929556005923	menaquinone biosynthesis protein, SCO4550 family; Region: mena_SCO4550; TIGR03699
929556005924	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929556005925	FeS/SAM binding site; other site
929556005926	Biotin and Thiamin Synthesis associated domain; Region: BATS; cl06149
929556005927	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
929556005928	uncharacterized flavoprotein, PP_4765 family; Region: flavo_PP4765; TIGR03862
929556005929	Predicted acetyltransferase [General function prediction only]; Region: COG2388
929556005930	Domain of unknown function (DUF4279); Region: DUF4279; pfam14106
929556005931	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556005932	Predicted acetyltransferase [General function prediction only]; Region: COG2388
929556005933	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556005934	F0F1 ATP synthase subunit B; Validated; Region: PRK06568
929556005935	DNA topoisomerase III; Provisional; Region: PRK07726
929556005936	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
929556005937	active site
929556005938	putative interdomain interaction site [polypeptide binding]; other site
929556005939	putative metal-binding site [ion binding]; other site
929556005940	putative nucleotide binding site [chemical binding]; other site
929556005941	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
929556005942	domain I; other site
929556005943	DNA binding groove [nucleotide binding]
929556005944	phosphate binding site [ion binding]; other site
929556005945	domain II; other site
929556005946	domain III; other site
929556005947	nucleotide binding site [chemical binding]; other site
929556005948	catalytic site [active]
929556005949	domain IV; other site
929556005950	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
929556005951	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
929556005952	putative catalytic site [active]
929556005953	putative phosphate binding site [ion binding]; other site
929556005954	active site
929556005955	metal binding site A [ion binding]; metal-binding site
929556005956	DNA binding site [nucleotide binding]
929556005957	putative AP binding site [nucleotide binding]; other site
929556005958	putative metal binding site B [ion binding]; other site
929556005959	Peroxiredoxin (PRX)-like 1 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a conserved cysteine that aligns to the first cysteine in the CXXC motif of TRX. This does not correspond to the peroxidatic...; Region: PRX_like1; cd02969
929556005960	putative catalytic residue [active]
929556005961	Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_2; cd04276
929556005962	active site
929556005963	Macro domain, Poa1p_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose...; Region: Macro_Poa1p_like; cd02901
929556005964	ADP-ribose binding site [chemical binding]; other site
929556005965	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556005966	FAD dependent oxidoreductase TIGR03364; Region: HpnW_proposed
929556005967	hydroxyglutarate oxidase; Provisional; Region: PRK11728
929556005968	phosphonatase-like hydrolase; Region: PhnX-like; TIGR03351
929556005969	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929556005970	motif II; other site
929556005971	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_22; cd08359
929556005972	putative dimer interface [polypeptide binding]; other site
929556005973	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556005974	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556005975	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
929556005976	Endoglucanase E-like members of the SGNH hydrolase family; Endoglucanase E catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; Region: Endoglucanase_E_like; cd01831
929556005977	active site
929556005978	catalytic triad [active]
929556005979	oxyanion hole [active]
929556005980	alpha-galactosidase; Region: PLN02808; cl17638
929556005981	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
929556005982	Endo-beta-mannanase [Carbohydrate transport and metabolism]; Region: COG3934
929556005983	Sugar-binding cellulase-like; Region: Cellulase-like; pfam12876
929556005984	Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; Region: IPT; cl15674
929556005985	IPT/TIG domain; Region: TIG; pfam01833
929556005986	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556005987	SusD family; Region: SusD; pfam07980
929556005988	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556005989	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556005990	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
929556005991	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183
929556005992	dimerization interface [polypeptide binding]; other site
929556005993	putative active cleft [active]
929556005994	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
929556005995	active site
929556005996	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u1; cd11477
929556005997	Na binding site [ion binding]; other site
929556005998	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
929556005999	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
929556006000	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556006001	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
929556006002	metal binding site 2 [ion binding]; metal-binding site
929556006003	putative DNA binding helix; other site
929556006004	metal binding site 1 [ion binding]; metal-binding site
929556006005	dimer interface [polypeptide binding]; other site
929556006006	structural Zn2+ binding site [ion binding]; other site
929556006007	Histidine kinase; Region: His_kinase; pfam06580
929556006008	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
929556006009	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556006010	active site
929556006011	phosphorylation site [posttranslational modification]
929556006012	intermolecular recognition site; other site
929556006013	dimerization interface [polypeptide binding]; other site
929556006014	LytTr DNA-binding domain; Region: LytTR; smart00850
929556006015	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
929556006016	Beta-lactamase; Region: Beta-lactamase; pfam00144
929556006017	DinB superfamily; Region: DinB_2; pfam12867
929556006018	RDD family; Region: RDD; pfam06271
929556006019	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_24; cd09012
929556006020	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556006021	PIF1-like helicase; Region: PIF1; pfam05970
929556006022	AAA domain; Region: AAA_30; pfam13604
929556006023	Family description; Region: UvrD_C_2; pfam13538
929556006024	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
929556006025	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
929556006026	putative DNA binding site [nucleotide binding]; other site
929556006027	putative Zn2+ binding site [ion binding]; other site
929556006028	AsnC family; Region: AsnC_trans_reg; pfam01037
929556006029	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
929556006030	EamA-like transporter family; Region: EamA; pfam00892
929556006031	YcfA-like protein; Region: YcfA; pfam07927
929556006032	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
929556006033	Zn binding site [ion binding]; other site
929556006034	active site
929556006035	metal binding site [ion binding]; metal-binding site
929556006036	Glyoxalase-like domain; Region: Glyoxalase_2; pfam12681
929556006037	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556006038	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cl00207
929556006039	Helix-turn-helix domain; Region: HTH_18; pfam12833
929556006040	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556006041	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
929556006042	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
929556006043	metal-binding site [ion binding]
929556006044	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929556006045	Soluble P-type ATPase [General function prediction only]; Region: COG4087
929556006046	Copper chaperone [Inorganic ion transport and metabolism]; Region: CopZ; COG2608
929556006047	metal-binding site [ion binding]
929556006048	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
929556006049	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
929556006050	Outer membrane efflux protein; Region: OEP; pfam02321
929556006051	Outer membrane efflux protein; Region: OEP; pfam02321
929556006052	HlyD family secretion protein; Region: HlyD_2; pfam12700
929556006053	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
929556006054	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556006055	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
929556006056	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
929556006057	lipoyl-biotinyl attachment site [posttranslational modification]; other site
929556006058	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556006059	Protein of unknown function (DUF3347); Region: DUF3347; pfam11827
929556006060	Uncharacterized protein conserved in bacteria (DUF2136); Region: DUF2136; pfam09907
929556006061	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929556006062	non-specific DNA binding site [nucleotide binding]; other site
929556006063	salt bridge; other site
929556006064	sequence-specific DNA binding site [nucleotide binding]; other site
929556006065	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929556006066	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929556006067	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
929556006068	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556006069	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
929556006070	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
929556006071	Walker A/P-loop; other site
929556006072	ATP binding site [chemical binding]; other site
929556006073	Q-loop/lid; other site
929556006074	ABC transporter signature motif; other site
929556006075	Walker B; other site
929556006076	D-loop; other site
929556006077	H-loop/switch region; other site
929556006078	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
929556006079	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
929556006080	Walker A/P-loop; other site
929556006081	ATP binding site [chemical binding]; other site
929556006082	Q-loop/lid; other site
929556006083	ABC transporter signature motif; other site
929556006084	Walker B; other site
929556006085	D-loop; other site
929556006086	H-loop/switch region; other site
929556006087	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
929556006088	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
929556006089	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
929556006090	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
929556006091	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
929556006092	Protein of unknown function (DUF1271); Region: DUF1271; pfam06902
929556006093	Zinc finger domain containing protein (CDGSH-type) [Function unknown]; Region: COG3369
929556006094	Iron-binding zinc finger CDGSH type; Region: zf-CDGSH; pfam09360
929556006095	GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518
929556006096	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741
929556006097	catalytic triad [active]
929556006098	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
929556006099	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
929556006100	Predicted aminopeptidases [General function prediction only]; Region: Iap; COG2234
929556006101	PA/protease or protease-like domain interface [polypeptide binding]; other site
929556006102	M28 Zn-Peptidases containing a PA domain insert; Region: M28_like_PA_1; cd05660
929556006103	metal binding site [ion binding]; metal-binding site
929556006104	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
929556006105	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
929556006106	DNA-binding site [nucleotide binding]; DNA binding site
929556006107	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
929556006108	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556006109	homodimer interface [polypeptide binding]; other site
929556006110	catalytic residue [active]
929556006111	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
929556006112	EamA-like transporter family; Region: EamA; pfam00892
929556006113	EamA-like transporter family; Region: EamA; pfam00892
929556006114	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556006115	Coenzyme A binding pocket [chemical binding]; other site
929556006116	Ion transport protein; Region: Ion_trans; pfam00520
929556006117	Ion channel; Region: Ion_trans_2; pfam07885
929556006118	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
929556006119	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
929556006120	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
929556006121	Walker A/P-loop; other site
929556006122	ATP binding site [chemical binding]; other site
929556006123	Q-loop/lid; other site
929556006124	ABC transporter signature motif; other site
929556006125	Walker B; other site
929556006126	D-loop; other site
929556006127	H-loop/switch region; other site
929556006128	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556006129	FtsX-like permease family; Region: FtsX; pfam02687
929556006130	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
929556006131	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
929556006132	catalytic residues [active]
929556006133	dimer interface [polypeptide binding]; other site
929556006134	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
929556006135	amphipathic channel; other site
929556006136	Asn-Pro-Ala signature motifs; other site
929556006137	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
929556006138	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
929556006139	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
929556006140	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
929556006141	Large-conductance mechanosensitive channel, MscL; Region: MscL; cl00860
929556006142	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
929556006143	Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454
929556006144	apolar tunnel; other site
929556006145	heme binding site [chemical binding]; other site
929556006146	dimerization interface [polypeptide binding]; other site
929556006147	Protein of unknown function (DUF3078); Region: DUF3078; pfam11276
929556006148	oxalate/formate antiporter; Region: oxa_formateAnti; TIGR04259
929556006149	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556006150	putative substrate translocation pore; other site
929556006151	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
929556006152	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
929556006153	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
929556006154	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929556006155	FeS/SAM binding site; other site
929556006156	Protein of unknown function, DUF399; Region: DUF399; pfam04187
929556006157	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
929556006158	ribonuclease P; Reviewed; Region: rnpA; PRK01903
929556006159	Haemolytic domain; Region: Haemolytic; pfam01809
929556006160	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
929556006161	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
929556006162	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
929556006163	protein binding site [polypeptide binding]; other site
929556006164	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
929556006165	Catalytic dyad [active]
929556006166	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
929556006167	Glycoprotease family; Region: Peptidase_M22; pfam00814
929556006168	Protein of unknown function (DUF3352); Region: DUF3352; pfam11832
929556006169	Protein of unknown function (DUF423); Region: DUF423; pfam04241
929556006170	primosome assembly protein PriA; Validated; Region: PRK05580
929556006171	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929556006172	ATP binding site [chemical binding]; other site
929556006173	putative Mg++ binding site [ion binding]; other site
929556006174	helicase superfamily c-terminal domain; Region: HELICc; smart00490
929556006175	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
929556006176	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
929556006177	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
929556006178	SmpB-tmRNA interface; other site
929556006179	manganese transport protein MntH; Reviewed; Region: PRK00701
929556006180	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
929556006181	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
929556006182	Ligand Binding Site [chemical binding]; other site
929556006183	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
929556006184	Helix-turn-helix diphteria tox regulatory element; Region: HTH_DTXR; smart00529
929556006185	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
929556006186	FeoA domain; Region: FeoA; pfam04023
929556006187	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
929556006188	putative DNA binding site [nucleotide binding]; other site
929556006189	putative Zn2+ binding site [ion binding]; other site
929556006190	AsnC family; Region: AsnC_trans_reg; pfam01037
929556006191	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
929556006192	ligand binding site [chemical binding]; other site
929556006193	active site
929556006194	UGI interface [polypeptide binding]; other site
929556006195	catalytic site [active]
929556006196	Lipocalin-like domain; Region: Lipocalin_4; pfam13648
929556006197	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
929556006198	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
929556006199	dimer interface [polypeptide binding]; other site
929556006200	putative anticodon binding site; other site
929556006201	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
929556006202	motif 1; other site
929556006203	active site
929556006204	motif 2; other site
929556006205	motif 3; other site
929556006206	Glycoside hydrolase 97; Region: Glyco_hydro_97; pfam10566
929556006207	Protein of unknown function (DUF962); Region: DUF962; pfam06127
929556006208	proline dehydrogenase; Region: PLN02681
929556006209	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
929556006210	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
929556006211	active site
929556006212	dimer interface [polypeptide binding]; other site
929556006213	metal binding site [ion binding]; metal-binding site
929556006214	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
929556006215	Prephenate dehydratase; Region: PDT; pfam00800
929556006216	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
929556006217	putative L-Phe binding site [chemical binding]; other site
929556006218	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
929556006219	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; cl17225
929556006220	Chorismate mutase type II; Region: CM_2; smart00830
929556006221	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
929556006222	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
929556006223	hinge; other site
929556006224	active site
929556006225	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
929556006226	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
929556006227	Tetramer interface [polypeptide binding]; other site
929556006228	active site
929556006229	FMN-binding site [chemical binding]; other site
929556006230	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
929556006231	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
929556006232	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
929556006233	active site
929556006234	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
929556006235	NADH(P)-binding; Region: NAD_binding_10; pfam13460
929556006236	NAD binding site [chemical binding]; other site
929556006237	substrate binding site [chemical binding]; other site
929556006238	putative active site [active]
929556006239	Protein of unknown function (DUF1697); Region: DUF1697; pfam08002
929556006240	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
929556006241	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
929556006242	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
929556006243	putative oxidoreductase; Provisional; Region: PRK11579
929556006244	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
929556006245	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
929556006246	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
929556006247	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
929556006248	nucleotide binding site [chemical binding]; other site
929556006249	Flagellin N-methylase; Region: FliB; pfam03692
929556006250	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
929556006251	active site
929556006252	metal binding site [ion binding]; metal-binding site
929556006253	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
929556006254	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
929556006255	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
929556006256	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
929556006257	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
929556006258	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
929556006259	RNA binding site [nucleotide binding]; other site
929556006260	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
929556006261	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
929556006262	CHAP domain; Region: CHAP; cl17642
929556006263	Rhomboid family; Region: Rhomboid; cl11446
929556006264	carboxy-terminal protease; Provisional; Region: PRK11186
929556006265	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
929556006266	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
929556006267	protein binding site [polypeptide binding]; other site
929556006268	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
929556006269	Catalytic dyad [active]
929556006270	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
929556006271	Immunoglobulin V-set domain; Region: V-set; pfam07686
929556006272	Immunoglobulin domain; Region: Ig; cd00096
929556006273	Immunoglobulin domain; Region: Ig; cd00096
929556006274	Immunoglobulin domain; Region: Ig_2; pfam13895
929556006275	Immunoglobulin I-set domain; Region: I-set; pfam07679
929556006276	Immunoglobulin domain; Region: Ig_2; pfam13895
929556006277	Immunoglobulin domain; Region: Ig_2; pfam13895
929556006278	Immunoglobulin I-set domain; Region: I-set; pfam07679
929556006279	Immunoglobulin domain; Region: Ig_2; pfam13895
929556006280	Immunoglobulin domain; Region: Ig_2; pfam13895
929556006281	Immunoglobulin I-set domain; Region: I-set; pfam07679
929556006282	Immunoglobulin; Region: IG; smart00409
929556006283	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556006284	Protein of unknown function (DUF3308); Region: DUF3308; cl14675
929556006285	Domain of unknown function (DUF4302); Region: DUF4302; pfam14135
929556006286	Phosphoenolpyruvate:glucose-phosphotransferase regulator; Region: MtfA; cl01267
929556006287	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556006288	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556006289	Secretin and TonB N terminus short domain; Region: STN; pfam07660
929556006290	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556006291	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556006292	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
929556006293	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556006294	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
929556006295	FecR protein; Region: FecR; pfam04773
929556006296	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
929556006297	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556006298	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
929556006299	DNA binding residues [nucleotide binding]
929556006300	ATP-dependent protease Lon; Provisional; Region: PRK13765
929556006301	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
929556006302	tetramer interface [polypeptide binding]; other site
929556006303	TPP-binding site [chemical binding]; other site
929556006304	heterodimer interface [polypeptide binding]; other site
929556006305	phosphorylation loop region [posttranslational modification]
929556006306	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
929556006307	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
929556006308	PYR/PP interface [polypeptide binding]; other site
929556006309	dimer interface [polypeptide binding]; other site
929556006310	TPP binding site [chemical binding]; other site
929556006311	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
929556006312	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
929556006313	aspartate aminotransferase; Provisional; Region: PRK07568
929556006314	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
929556006315	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556006316	homodimer interface [polypeptide binding]; other site
929556006317	catalytic residue [active]
929556006318	Domain of unknown function (DUF4386); Region: DUF4386; pfam14329
929556006319	ZU5 domain; Region: ZU5; cl02517
929556006320	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556006321	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556006322	ligand binding site [chemical binding]; other site
929556006323	flexible hinge region; other site
929556006324	Predicted transcriptional regulators [Transcription]; Region: COG1733
929556006325	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
929556006326	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
929556006327	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929556006328	NAD(P) binding site [chemical binding]; other site
929556006329	active site
929556006330	polyphosphate kinase 2, PA0141 family; Region: PPK2_P_aer; TIGR03707
929556006331	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
929556006332	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
929556006333	Sulfate transporter family; Region: Sulfate_transp; pfam00916
929556006334	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
929556006335	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
929556006336	L-2-amino-thiazoline-4-carboxylic acid hydrolase; Region: ATC_hydrolase; pfam14196
929556006337	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
929556006338	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929556006339	Helix-turn-helix domain; Region: HTH_18; pfam12833
929556006340	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556006341	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
929556006342	Beta-lactamase; Region: Beta-lactamase; pfam00144
929556006343	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556006344	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556006345	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
929556006346	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556006347	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
929556006348	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
929556006349	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
929556006350	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
929556006351	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
929556006352	Predicted acetyltransferase [General function prediction only]; Region: COG2388
929556006353	RNA polymerase sigma factor; Provisional; Region: PRK11922
929556006354	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556006355	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556006356	DNA binding residues [nucleotide binding]
929556006357	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
929556006358	putative ABC transporter; Region: ycf24; CHL00085
929556006359	FeS assembly ATPase SufC; Region: sufC; TIGR01978
929556006360	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
929556006361	Walker A/P-loop; other site
929556006362	ATP binding site [chemical binding]; other site
929556006363	Q-loop/lid; other site
929556006364	ABC transporter signature motif; other site
929556006365	Walker B; other site
929556006366	D-loop; other site
929556006367	H-loop/switch region; other site
929556006368	FeS assembly protein SufD; Region: sufD; TIGR01981
929556006369	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
929556006370	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
929556006371	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
929556006372	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929556006373	catalytic residue [active]
929556006374	Fe-S metabolism associated domain; Region: SufE; cl00951
929556006375	FeS assembly SUF system protein; Region: SUF_assoc; TIGR02945
929556006376	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
929556006377	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556006378	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556006379	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556006380	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556006381	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556006382	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556006383	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556006384	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556006385	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556006386	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556006387	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556006388	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556006389	Cadherin repeats; Region: CA; smart00112
929556006390	Ca2+ binding site [ion binding]; other site
929556006391	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556006392	Microcystin-dependent protein [Function unknown]; Region: MdpB; COG4675
929556006393	Phage Tail Collar Domain; Region: Collar; pfam07484
929556006394	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
929556006395	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
929556006396	active site
929556006397	metal binding site [ion binding]; metal-binding site
929556006398	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
929556006399	ligand-binding site [chemical binding]; other site
929556006400	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
929556006401	Aspartyl/Asparaginyl beta-hydroxylase; Region: Asp_Arg_Hydrox; cl17820
929556006402	Protein of unknown function (DUF983); Region: DUF983; cl02211
929556006403	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
929556006404	Helix-turn-helix domain; Region: HTH_18; pfam12833
929556006405	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556006406	dihydrolipoamide dehydrogenase; Region: lipoamide_DH; TIGR01350
929556006407	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
929556006408	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929556006409	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
929556006410	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
929556006411	Sulfatase; Region: Sulfatase; pfam00884
929556006412	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
929556006413	active site
929556006414	Zn binding site [ion binding]; other site
929556006415	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
929556006416	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556006417	ligand binding site [chemical binding]; other site
929556006418	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
929556006419	ZU5 domain; Region: ZU5; cl02517
929556006420	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
929556006421	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556006422	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556006423	binding surface
929556006424	TPR motif; other site
929556006425	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556006426	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556006427	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556006428	binding surface
929556006429	TPR motif; other site
929556006430	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556006431	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556006432	binding surface
929556006433	TPR motif; other site
929556006434	TPR repeat; Region: TPR_11; pfam13414
929556006435	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
929556006436	Histidine kinase; Region: HisKA_3; pfam07730
929556006437	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556006438	ATP binding site [chemical binding]; other site
929556006439	Mg2+ binding site [ion binding]; other site
929556006440	G-X-G motif; other site
929556006441	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556006442	binding surface
929556006443	TPR motif; other site
929556006444	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556006445	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556006446	Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins; Region: DHR2_DOCK; cl06123
929556006447	dimer interface [polypeptide binding]; other site
929556006448	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556006449	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
929556006450	Histidine kinase; Region: HisKA_3; pfam07730
929556006451	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556006452	ATP binding site [chemical binding]; other site
929556006453	Mg2+ binding site [ion binding]; other site
929556006454	G-X-G motif; other site
929556006455	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
929556006456	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556006457	active site
929556006458	phosphorylation site [posttranslational modification]
929556006459	intermolecular recognition site; other site
929556006460	dimerization interface [polypeptide binding]; other site
929556006461	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
929556006462	dimerization interface [polypeptide binding]; other site
929556006463	DNA binding residues [nucleotide binding]
929556006464	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
929556006465	putative active site [active]
929556006466	putative metal binding site [ion binding]; other site
929556006467	amidase; Provisional; Region: PRK08137
929556006468	Amidase; Region: Amidase; pfam01425
929556006469	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01096
929556006470	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
929556006471	Protein of unknown function (DUF3370); Region: DUF3370; pfam11850
929556006472	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u1; cd11477
929556006473	Na binding site [ion binding]; other site
929556006474	sialate_O-acetylesterase_like subfamily of the SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: sialate_O-acetylesterase_like2; cd01828
929556006475	active site
929556006476	catalytic triad [active]
929556006477	oxyanion hole [active]
929556006478	sialate_O-acetylesterase_like subfamily of the SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: sialate_O-acetylesterase_like2; cd01828
929556006479	active site
929556006480	catalytic triad [active]
929556006481	oxyanion hole [active]
929556006482	sialate_O-acetylesterase_like subfamily of the SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: sialate_O-acetylesterase_like2; cd01828
929556006483	active site
929556006484	catalytic triad [active]
929556006485	oxyanion hole [active]
929556006486	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
929556006487	dimerization interface [polypeptide binding]; other site
929556006488	putative active cleft [active]
929556006489	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
929556006490	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556006491	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
929556006492	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
929556006493	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
929556006494	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556006495	starch binding outer membrane protein SusD; Region: SusD; cl17845
929556006496	SusD family; Region: SusD; pfam07980
929556006497	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556006498	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556006499	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556006500	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556006501	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
929556006502	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
929556006503	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
929556006504	nucleotide binding site [chemical binding]; other site
929556006505	Transcriptional regulators [Transcription]; Region: PurR; COG1609
929556006506	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
929556006507	DNA binding site [nucleotide binding]
929556006508	domain linker motif; other site
929556006509	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
929556006510	dimerization interface [polypeptide binding]; other site
929556006511	ligand binding site [chemical binding]; other site
929556006512	Domain of unknown function (DUF3472); Region: DUF3472; pfam11958
929556006513	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
929556006514	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
929556006515	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556006516	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556006517	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
929556006518	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556006519	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556006520	Phosphotransferase enzyme family; Region: APH; pfam01636
929556006521	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
929556006522	substrate binding site [chemical binding]; other site
929556006523	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
929556006524	intracellular protease, PfpI family; Region: PfpI; TIGR01382
929556006525	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_1; cd03169
929556006526	conserved cys residue [active]
929556006527	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
929556006528	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
929556006529	active site
929556006530	HIGH motif; other site
929556006531	dimer interface [polypeptide binding]; other site
929556006532	KMSKS motif; other site
929556006533	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
929556006534	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
929556006535	nucleotide binding pocket [chemical binding]; other site
929556006536	K-X-D-G motif; other site
929556006537	catalytic site [active]
929556006538	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
929556006539	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
929556006540	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
929556006541	Dimer interface [polypeptide binding]; other site
929556006542	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
929556006543	dihydrodipicolinate synthase; Region: dapA; TIGR00674
929556006544	dimer interface [polypeptide binding]; other site
929556006545	active site
929556006546	catalytic residue [active]
929556006547	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
929556006548	heme-binding site [chemical binding]; other site
929556006549	Uncharacterized conserved protein [Function unknown]; Region: COG3538
929556006550	Protein of unknown function (DUF1237); Region: DUF1237; pfam06824
929556006551	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
929556006552	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
929556006553	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929556006554	catalytic residue [active]
929556006555	Cell division GTPase [Cell division and chromosome partitioning]; Region: FtsZ; COG0206
929556006556	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
929556006557	nucleotide binding site [chemical binding]; other site
929556006558	SulA interaction site; other site
929556006559	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
929556006560	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
929556006561	nucleotide binding site [chemical binding]; other site
929556006562	SHS2 domain inserted in FTSA; Region: SHS2_FTSA; pfam02491
929556006563	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
929556006564	Cell division protein FtsA; Region: FtsA; pfam14450
929556006565	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
929556006566	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
929556006567	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
929556006568	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
929556006569	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
929556006570	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
929556006571	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
929556006572	active site
929556006573	homodimer interface [polypeptide binding]; other site
929556006574	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
929556006575	UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell envelope biogenesis, outer membrane]; Region: MurD; COG0771
929556006576	Alanine dehydrogenase/PNT, C-terminal domain; Region: AlaDh_PNT_C; smart01002
929556006577	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
929556006578	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
929556006579	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
929556006580	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
929556006581	Mg++ binding site [ion binding]; other site
929556006582	putative catalytic motif [active]
929556006583	putative substrate binding site [chemical binding]; other site
929556006584	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
929556006585	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
929556006586	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
929556006587	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
929556006588	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
929556006589	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
929556006590	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
929556006591	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
929556006592	MraW methylase family; Region: Methyltransf_5; cl17771
929556006593	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
929556006594	cell division protein MraZ; Reviewed; Region: PRK00326
929556006595	MraZ protein; Region: MraZ; pfam02381
929556006596	MraZ protein; Region: MraZ; pfam02381
929556006597	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
929556006598	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
929556006599	Phosphoglycerate kinase; Region: PGK; pfam00162
929556006600	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
929556006601	substrate binding site [chemical binding]; other site
929556006602	hinge regions; other site
929556006603	ADP binding site [chemical binding]; other site
929556006604	catalytic site [active]
929556006605	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
929556006606	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
929556006607	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
929556006608	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556006609	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
929556006610	starch binding outer membrane protein SusD; Region: SusD; cl17845
929556006611	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556006612	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556006613	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556006614	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556006615	Alpha-L-fucosidase; Region: Alpha_L_fucos; pfam01120
929556006616	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
929556006617	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
929556006618	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
929556006619	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
929556006620	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
929556006621	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
929556006622	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
929556006623	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
929556006624	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
929556006625	active site
929556006626	Fn3 associated; Region: Fn3_assoc; pfam13287
929556006627	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
929556006628	starch binding outer membrane protein SusD; Region: SusD; cl17845
929556006629	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556006630	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556006631	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556006632	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556006633	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
929556006634	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
929556006635	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556006636	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556006637	ligand binding site [chemical binding]; other site
929556006638	flexible hinge region; other site
929556006639	FemAB family; Region: FemAB; pfam02388
929556006640	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
929556006641	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556006642	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
929556006643	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556006644	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556006645	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
929556006646	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
929556006647	N-terminal plug; other site
929556006648	ligand-binding site [chemical binding]; other site
929556006649	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
929556006650	Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by...; Region: PRX_1cys; cd03016
929556006651	dimer interface [polypeptide binding]; other site
929556006652	decamer (pentamer of dimers) interface [polypeptide binding]; other site
929556006653	catalytic triad [active]
929556006654	putative transporter; Validated; Region: PRK03818
929556006655	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
929556006656	TrkA-C domain; Region: TrkA_C; pfam02080
929556006657	TrkA-C domain; Region: TrkA_C; pfam02080
929556006658	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
929556006659	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_GTP; cd00819
929556006660	active site
929556006661	substrate-binding site [chemical binding]; other site
929556006662	metal-binding site [ion binding]
929556006663	GTP binding site [chemical binding]; other site
929556006664	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
929556006665	MgtC family; Region: MgtC; pfam02308
929556006666	Transposase, Mutator family; Region: Transposase_mut; pfam00872
929556006667	MULE transposase domain; Region: MULE; pfam10551
929556006668	GTPase CgtA; Reviewed; Region: obgE; PRK12299
929556006669	GTP1/OBG; Region: GTP1_OBG; pfam01018
929556006670	Obg GTPase; Region: Obg; cd01898
929556006671	G1 box; other site
929556006672	GTP/Mg2+ binding site [chemical binding]; other site
929556006673	Switch I region; other site
929556006674	G2 box; other site
929556006675	G3 box; other site
929556006676	Switch II region; other site
929556006677	G4 box; other site
929556006678	G5 box; other site
929556006679	adenylate kinase; Reviewed; Region: adk; PRK00279
929556006680	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
929556006681	AMP-binding site [chemical binding]; other site
929556006682	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
929556006683	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
929556006684	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
929556006685	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
929556006686	ligand binding site [chemical binding]; other site
929556006687	hypothetical protein; Provisional; Region: PRK13665
929556006688	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
929556006689	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
929556006690	NADP binding site [chemical binding]; other site
929556006691	active site
929556006692	putative substrate binding site [chemical binding]; other site
929556006693	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
929556006694	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
929556006695	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
929556006696	alpha subunit interaction interface [polypeptide binding]; other site
929556006697	Walker A motif; other site
929556006698	ATP binding site [chemical binding]; other site
929556006699	Walker B motif; other site
929556006700	inhibitor binding site; inhibition site
929556006701	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
929556006702	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
929556006703	gamma subunit interface [polypeptide binding]; other site
929556006704	LBP interface [polypeptide binding]; other site
929556006705	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
929556006706	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
929556006707	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347
929556006708	Uncharacterized conserved protein (DUF2132); Region: DUF2132; pfam09905
929556006709	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
929556006710	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
929556006711	Walker A/P-loop; other site
929556006712	ATP binding site [chemical binding]; other site
929556006713	Q-loop/lid; other site
929556006714	ABC transporter signature motif; other site
929556006715	Walker B; other site
929556006716	D-loop; other site
929556006717	H-loop/switch region; other site
929556006718	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
929556006719	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
929556006720	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556006721	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556006722	DNA binding residues [nucleotide binding]
929556006723	Transcriptional regulators [Transcription]; Region: PurR; COG1609
929556006724	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
929556006725	DNA binding site [nucleotide binding]
929556006726	domain linker motif; other site
929556006727	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
929556006728	dimerization interface [polypeptide binding]; other site
929556006729	ligand binding site [chemical binding]; other site
929556006730	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
929556006731	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
929556006732	trehalose synthase; Region: treS_nterm; TIGR02456
929556006733	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
929556006734	active site
929556006735	catalytic site [active]
929556006736	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
929556006737	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
929556006738	Bacterial protein of unknown function (DUF885); Region: DUF885; pfam05960
929556006739	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
929556006740	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
929556006741	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
929556006742	substrate binding site [chemical binding]; other site
929556006743	active site
929556006744	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929556006745	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556006746	active site
929556006747	phosphorylation site [posttranslational modification]
929556006748	intermolecular recognition site; other site
929556006749	dimerization interface [polypeptide binding]; other site
929556006750	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929556006751	DNA binding site [nucleotide binding]
929556006752	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
929556006753	putative active site [active]
929556006754	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556006755	dimer interface [polypeptide binding]; other site
929556006756	phosphorylation site [posttranslational modification]
929556006757	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556006758	ATP binding site [chemical binding]; other site
929556006759	Mg2+ binding site [ion binding]; other site
929556006760	G-X-G motif; other site
929556006761	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
929556006762	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
929556006763	inhibitor-cofactor binding pocket; inhibition site
929556006764	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556006765	catalytic residue [active]
929556006766	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
929556006767	dimer interface [polypeptide binding]; other site
929556006768	active site
929556006769	Schiff base residues; other site
929556006770	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
929556006771	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
929556006772	domain interfaces; other site
929556006773	active site
929556006774	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
929556006775	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
929556006776	active site
929556006777	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
929556006778	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
929556006779	tRNA; other site
929556006780	putative tRNA binding site [nucleotide binding]; other site
929556006781	putative NADP binding site [chemical binding]; other site
929556006782	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Provisional; Region: PRK02048
929556006783	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
929556006784	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
929556006785	PspC domain; Region: PspC; pfam04024
929556006786	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
929556006787	classical (c) SDRs; Region: SDR_c; cd05233
929556006788	NAD(P) binding site [chemical binding]; other site
929556006789	active site
929556006790	Permease; Region: Permease; pfam02405
929556006791	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
929556006792	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
929556006793	Walker A/P-loop; other site
929556006794	ATP binding site [chemical binding]; other site
929556006795	Q-loop/lid; other site
929556006796	ABC transporter signature motif; other site
929556006797	Walker B; other site
929556006798	D-loop; other site
929556006799	H-loop/switch region; other site
929556006800	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
929556006801	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556006802	S-adenosylmethionine binding site [chemical binding]; other site
929556006803	N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3653
929556006804	D-aminoacylases (N-acyl-D-Amino acid amidohydrolases) catalyze the hydrolysis of N-acyl-D-amino acids to produce the corresponding D-amino acids, which are used as intermediates in the synthesis of pesticides, bioactive peptides, and antibiotics; Region: D-aminoacylase; cd01297
929556006805	active site
929556006806	putative substrate binding pocket [chemical binding]; other site
929556006807	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
929556006808	Protein of unknown function (DUF4197); Region: DUF4197; pfam13852
929556006809	DNA topoisomerase IV subunit A; Provisional; Region: PRK12758
929556006810	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cl00148
929556006811	CAP-like domain; other site
929556006812	active site
929556006813	primary dimer interface [polypeptide binding]; other site
929556006814	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
929556006815	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556006816	ATP binding site [chemical binding]; other site
929556006817	Mg2+ binding site [ion binding]; other site
929556006818	G-X-G motif; other site
929556006819	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of type II DNA topoisomerases (Topo II) and DNA mismatch repair (MutL/MLH1/PMS2) proteins. This transducer domain is homologous to the second...; Region: TopoII_MutL_Trans; cl02783
929556006820	ATP binding site [chemical binding]; other site
929556006821	TOPRIM_TopoIIA_like: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to Saccharomyces cerevisiae Topoisomerase II. TopoIIA enzymes cut both strands...; Region: TOPRIM_TopoIIA_like; cd01030
929556006822	active site
929556006823	putative metal-binding site [ion binding]; other site
929556006824	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
929556006825	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
929556006826	active site
929556006827	catalytic triad [active]
929556006828	oxyanion hole [active]
929556006829	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
929556006830	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
929556006831	Cl- selectivity filter; other site
929556006832	Cl- binding residues [ion binding]; other site
929556006833	pore gating glutamate residue; other site
929556006834	dimer interface [polypeptide binding]; other site
929556006835	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with either the SpoIVFB domain (sporulation protein, stage IV cell wall formation, F locus, promoter-distal B) or the chloride channel protein EriC; Region: CBS_pair_SpoIVFB_EriC_assoc2; cd04613
929556006836	FOG: CBS domain [General function prediction only]; Region: COG0517
929556006837	Serine acetyltransferase, N-terminal; Region: SATase_N; cl05762
929556006838	serine O-acetyltransferase; Region: cysE; TIGR01172
929556006839	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
929556006840	trimer interface [polypeptide binding]; other site
929556006841	active site
929556006842	substrate binding site [chemical binding]; other site
929556006843	CoA binding site [chemical binding]; other site
929556006844	cysteine synthase B; Region: cysM; TIGR01138
929556006845	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
929556006846	dimer interface [polypeptide binding]; other site
929556006847	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556006848	catalytic residue [active]
929556006849	Protein of unknown function (DUF1345); Region: DUF1345; pfam07077
929556006850	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
929556006851	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
929556006852	Cl- selectivity filter; other site
929556006853	Cl- binding residues [ion binding]; other site
929556006854	pore gating glutamate residue; other site
929556006855	dimer interface [polypeptide binding]; other site
929556006856	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
929556006857	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556006858	global nitrogen regulator NtcA, cyanobacterial; Region: NtcA_cyano; TIGR03697
929556006859	ligand binding site [chemical binding]; other site
929556006860	flexible hinge region; other site
929556006861	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
929556006862	putative switch regulator; other site
929556006863	non-specific DNA interactions [nucleotide binding]; other site
929556006864	DNA binding site [nucleotide binding]
929556006865	sequence specific DNA binding site [nucleotide binding]; other site
929556006866	putative cAMP binding site [chemical binding]; other site
929556006867	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
929556006868	M28 Zn-Peptidase IAP aminopeptidase may contain PA domain insert; Region: M28_like_5; cd08021
929556006869	Peptidase family M28; Region: Peptidase_M28; pfam04389
929556006870	metal binding site [ion binding]; metal-binding site
929556006871	Repair protein; Region: Repair_PSII; pfam04536
929556006872	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929556006873	FeS/SAM binding site; other site
929556006874	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
929556006875	active site
929556006876	metal binding site [ion binding]; metal-binding site
929556006877	interdomain interaction site; other site
929556006878	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
929556006879	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
929556006880	non-specific DNA binding site [nucleotide binding]; other site
929556006881	salt bridge; other site
929556006882	sequence-specific DNA binding site [nucleotide binding]; other site
929556006883	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
929556006884	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
929556006885	Phosphopantetheine attachment site; Region: PP-binding; cl09936
929556006886	hypothetical protein; Provisional; Region: PRK10030
929556006887	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
929556006888	putative hydrophobic ligand binding site [chemical binding]; other site
929556006889	The SYLF domain (also called DUF500), a novel lipid-binding module; Region: SYLF; cl01109
929556006890	Type 1 glutamine amidotransferase (GATase1)-like domain found in cyanophycinase; Region: GAT1_cyanophycinase; cd03145
929556006891	proposed catalytic triad [active]
929556006892	active site nucleophile [active]
929556006893	PBP superfamily domain; Region: PBP_like_2; cl17296
929556006894	Uncharacterized conserved protein [Function unknown]; Region: COG1262
929556006895	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
929556006896	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
929556006897	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
929556006898	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Ada; COG2169
929556006899	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
929556006900	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
929556006901	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
929556006902	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
929556006903	DNA binding site [nucleotide binding]
929556006904	active site
929556006905	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556006906	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556006907	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556006908	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
929556006909	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
929556006910	N-terminal plug; other site
929556006911	ligand-binding site [chemical binding]; other site
929556006912	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
929556006913	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
929556006914	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
929556006915	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
929556006916	Tic20-like protein; Region: Tic20; pfam09685
929556006917	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
929556006918	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
929556006919	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
929556006920	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
929556006921	acetyl-CoA synthetase; Provisional; Region: PRK00174
929556006922	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
929556006923	active site
929556006924	CoA binding site [chemical binding]; other site
929556006925	acyl-activating enzyme (AAE) consensus motif; other site
929556006926	AMP binding site [chemical binding]; other site
929556006927	acetate binding site [chemical binding]; other site
929556006928	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
929556006929	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
929556006930	Domain of unknown function (DUF4295); Region: DUF4295; pfam14128
929556006931	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
929556006932	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
929556006933	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
929556006934	ribosomal protein S12 methylthiotransferase RimO; Region: TIGR01125
929556006935	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
929556006936	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929556006937	FeS/SAM binding site; other site
929556006938	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
929556006939	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
929556006940	Uncharacterized protein conserved in bacteria (DUF2317); Region: DUF2317; pfam10079
929556006941	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4365
929556006942	Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055
929556006943	prephenate dehydrogenase; Validated; Region: PRK08507
929556006944	Prephenate dehydrogenase [Amino acid transport and metabolism]; Region: TyrA; COG0287
929556006945	nitrite reductase, copper-containing; Region: Cu_nitrite_red; TIGR02376
929556006946	Multicopper oxidase; Region: Cu-oxidase; pfam00394
929556006947	Cytochrome c; Region: Cytochrom_C; cl11414
929556006948	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
929556006949	Cytochrome c; Region: Cytochrom_C; pfam00034
929556006950	Uncharacterized conserved protein [Function unknown]; Region: COG1262
929556006951	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
929556006952	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
929556006953	Cu(I) binding site [ion binding]; other site
929556006954	MG2 domain; Region: A2M_N; pfam01835
929556006955	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556006956	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556006957	Alpha-2-macroglobulin family; Region: A2M; pfam00207
929556006958	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
929556006959	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556006960	Major Facilitator Superfamily; Region: MFS_1; pfam07690
929556006961	putative substrate translocation pore; other site
929556006962	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_14; cd13139
929556006963	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
929556006964	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
929556006965	Catalytic site [active]
929556006966	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
929556006967	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
929556006968	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
929556006969	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
929556006970	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
929556006971	ParB-like nuclease domain; Region: ParBc; pfam02195
929556006972	KorB domain; Region: KorB; pfam08535
929556006973	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
929556006974	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
929556006975	P-loop; other site
929556006976	Magnesium ion binding site [ion binding]; other site
929556006977	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
929556006978	Magnesium ion binding site [ion binding]; other site
929556006979	Predicted flavoprotein [General function prediction only]; Region: COG0431
929556006980	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
929556006981	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
929556006982	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
929556006983	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
929556006984	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929556006985	motif II; other site
929556006986	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
929556006987	TIGR01777 family protein; Region: yfcH
929556006988	putative NAD(P) binding site [chemical binding]; other site
929556006989	putative active site [active]
929556006990	Predicted transcriptional regulators [Transcription]; Region: COG1510
929556006991	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556006992	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
929556006993	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556006994	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
929556006995	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556006996	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556006997	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
929556006998	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556006999	active site
929556007000	phosphorylation site [posttranslational modification]
929556007001	intermolecular recognition site; other site
929556007002	dimerization interface [polypeptide binding]; other site
929556007003	LytTr DNA-binding domain; Region: LytTR; smart00850
929556007004	Histidine kinase; Region: His_kinase; pfam06580
929556007005	Domain of unknown function (DUF1508); Region: DUF1508; cl01356
929556007006	Domain of unknown function (DUF1508); Region: DUF1508; cl01356
929556007007	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556007008	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
929556007009	ligand binding site [chemical binding]; other site
929556007010	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929556007011	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929556007012	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556007013	Major Facilitator Superfamily; Region: MFS_1; pfam07690
929556007014	putative substrate translocation pore; other site
929556007015	Nitric oxide reductase large subunit [Inorganic ion transport and metabolism]; Region: NorB; COG3256
929556007016	Rrf2 family protein; Region: rrf2_super; TIGR00738
929556007017	Transcriptional regulator; Region: Rrf2; pfam02082
929556007018	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
929556007019	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556007020	Walker A/P-loop; other site
929556007021	ATP binding site [chemical binding]; other site
929556007022	Q-loop/lid; other site
929556007023	ABC transporter signature motif; other site
929556007024	Walker B; other site
929556007025	D-loop; other site
929556007026	H-loop/switch region; other site
929556007027	ABC transporter; Region: ABC_tran_2; pfam12848
929556007028	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929556007029	apolipoprotein N-acyltransferase; Region: lnt; TIGR00546
929556007030	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
929556007031	active site
929556007032	catalytic triad [active]
929556007033	dimer interface [polypeptide binding]; other site
929556007034	Domain of unknown function (DUF955); Region: DUF955; pfam06114
929556007035	serine racemase; Region: PLN02970
929556007036	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
929556007037	tetramer interface [polypeptide binding]; other site
929556007038	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556007039	catalytic residue [active]
929556007040	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
929556007041	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556007042	Coenzyme A binding pocket [chemical binding]; other site
929556007043	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
929556007044	SnoaL-like domain; Region: SnoaL_2; pfam12680
929556007045	RibD C-terminal domain; Region: RibD_C; cl17279
929556007046	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
929556007047	DinB superfamily; Region: DinB_2; pfam12867
929556007048	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
929556007049	dimer interface [polypeptide binding]; other site
929556007050	maltose O-acetyltransferase; Provisional; Region: PRK10092
929556007051	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
929556007052	active site
929556007053	substrate binding site [chemical binding]; other site
929556007054	trimer interface [polypeptide binding]; other site
929556007055	CoA binding site [chemical binding]; other site
929556007056	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
929556007057	nicotinate phosphoribosyltransferase; Provisional; Region: PRK05321
929556007058	active site
929556007059	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
929556007060	classical (c) SDRs; Region: SDR_c; cd05233
929556007061	NAD(P) binding site [chemical binding]; other site
929556007062	active site
929556007063	short chain dehydrogenase; Provisional; Region: PRK06172
929556007064	classical (c) SDRs; Region: SDR_c; cd05233
929556007065	NAD(P) binding site [chemical binding]; other site
929556007066	active site
929556007067	glutamate racemase; Provisional; Region: PRK00865
929556007068	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
929556007069	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556007070	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556007071	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556007072	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556007073	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556007074	SusD family; Region: SusD; pfam07980
929556007075	Uncharacterized glycoside hydrolase family 99-like domain; Region: GH99_GH71_like_3; cd11575
929556007076	putative ligand binding site [chemical binding]; other site
929556007077	putative catalytic site [active]
929556007078	Glycoside hydrolase 97; Region: Glyco_hydro_97; pfam10566
929556007079	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
929556007080	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
929556007081	active site
929556007082	catalytic site [active]
929556007083	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
929556007084	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
929556007085	ATP binding site [chemical binding]; other site
929556007086	Mg++ binding site [ion binding]; other site
929556007087	motif III; other site
929556007088	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929556007089	nucleotide binding region [chemical binding]; other site
929556007090	ATP-binding site [chemical binding]; other site
929556007091	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556007092	leucyl-tRNA synthetase, eubacterial and mitochondrial family; Region: leuS_bact; TIGR00396
929556007093	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
929556007094	active site
929556007095	HIGH motif; other site
929556007096	nucleotide binding site [chemical binding]; other site
929556007097	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
929556007098	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
929556007099	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
929556007100	active site
929556007101	KMSKS motif; other site
929556007102	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
929556007103	tRNA binding surface [nucleotide binding]; other site
929556007104	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
929556007105	Protein of unknown function (DUF3098); Region: DUF3098; pfam11297
929556007106	Bacitracin resistance protein BacA; Region: BacA; pfam02673
929556007107	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
929556007108	tRNA pseudouridine(55) synthase; Region: TruB; TIGR00431
929556007109	RNA binding site [nucleotide binding]; other site
929556007110	active site
929556007111	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
929556007112	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
929556007113	active site
929556007114	Riboflavin kinase; Region: Flavokinase; pfam01687
929556007115	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
929556007116	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
929556007117	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
929556007118	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
929556007119	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
929556007120	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
929556007121	RNA polymerase sigma factor; Provisional; Region: PRK12513
929556007122	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556007123	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556007124	DNA binding residues [nucleotide binding]
929556007125	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
929556007126	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556007127	S-adenosylmethionine binding site [chemical binding]; other site
929556007128	Predicted membrane protein [Function unknown]; Region: COG3650
929556007129	aconitate hydratase; Validated; Region: PRK07229
929556007130	Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: AcnA_Mitochondrial; cd01584
929556007131	substrate binding site [chemical binding]; other site
929556007132	ligand binding site [chemical binding]; other site
929556007133	Mitochondrial aconitase A swivel domain. Aconitase (also known as aconitate hydratase and citrate hydro-lyase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes...; Region: AcnA_Mitochon_Swivel; cd01578
929556007134	substrate binding site [chemical binding]; other site
929556007135	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
929556007136	FOG: PKD repeat [General function prediction only]; Region: COG3291
929556007137	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
929556007138	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556007139	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
929556007140	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
929556007141	active site
929556007142	Domain of unknown function (DUF4289); Region: DUF4289; pfam14121
929556007143	purine nucleoside phosphorylase; Provisional; Region: PRK08202
929556007144	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
929556007145	Tetraacyldisaccharide-1-P 4'-kinase; Region: LpxK; pfam02606
929556007146	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
929556007147	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
929556007148	Predicted membrane protein [Function unknown]; Region: COG3059
929556007149	Helix-turn-helix domain; Region: HTH_18; pfam12833
929556007150	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556007151	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
929556007152	Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17; Region: ALDH_F4-17_P5CDH; cd07123
929556007153	delta-1-pyrroline-5-carboxylate dehydrogenase, group 1; Region: D1pyr5carbox1; TIGR01236
929556007154	Glutamate binding site [chemical binding]; other site
929556007155	NAD binding site [chemical binding]; other site
929556007156	catalytic residues [active]
929556007157	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
929556007158	Cytochrome c; Region: Cytochrom_C; pfam00034
929556007159	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
929556007160	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
929556007161	nucleotide binding site [chemical binding]; other site
929556007162	NEF interaction site [polypeptide binding]; other site
929556007163	SBD interface [polypeptide binding]; other site
929556007164	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
929556007165	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
929556007166	SLBB domain; Region: SLBB; pfam10531
929556007167	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
929556007168	Chain length determinant protein; Region: Wzz; cl15801
929556007169	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
929556007170	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
929556007171	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_epsE_like; cd13129
929556007172	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
929556007173	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
929556007174	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
929556007175	Probable Catalytic site; other site
929556007176	metal-binding site
929556007177	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
929556007178	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
929556007179	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
929556007180	This family is most closely related to the GT1 family of glycosyltransferases. Bme6 in Brucella melitensis has been shown to be involved in the biosynthesis of a polysaccharide; Region: GT1_Bme6_like; cd03821
929556007181	putative ADP-binding pocket [chemical binding]; other site
929556007182	Acyltransferase family; Region: Acyl_transf_3; pfam01757
929556007183	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
929556007184	putative trimer interface [polypeptide binding]; other site
929556007185	putative active site [active]
929556007186	putative substrate binding site [chemical binding]; other site
929556007187	putative CoA binding site [chemical binding]; other site
929556007188	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
929556007189	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
929556007190	putative metal binding site; other site
929556007191	putative glycosyl transferase; Provisional; Region: PRK10307
929556007192	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
929556007193	Undecaprenyl-phosphate glucose phosphotransferase; Region: WcaJ_sugtrans; TIGR03023
929556007194	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
929556007195	Bacterial sugar transferase; Region: Bac_transf; pfam02397
929556007196	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
929556007197	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
929556007198	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
929556007199	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
929556007200	alphaNTD homodimer interface [polypeptide binding]; other site
929556007201	alphaNTD - beta interaction site [polypeptide binding]; other site
929556007202	alphaNTD - beta' interaction site [polypeptide binding]; other site
929556007203	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
929556007204	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
929556007205	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
929556007206	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
929556007207	RNA binding surface [nucleotide binding]; other site
929556007208	30S ribosomal protein S11; Validated; Region: PRK05309
929556007209	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
929556007210	30S ribosomal protein S13; Region: bact_S13; TIGR03631
929556007211	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
929556007212	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
929556007213	rRNA binding site [nucleotide binding]; other site
929556007214	predicted 30S ribosome binding site; other site
929556007215	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
929556007216	active site
929556007217	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
929556007218	SecY translocase; Region: SecY; pfam00344
929556007219	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
929556007220	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
929556007221	23S rRNA binding site [nucleotide binding]; other site
929556007222	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
929556007223	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
929556007224	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
929556007225	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
929556007226	23S rRNA interface [nucleotide binding]; other site
929556007227	L21e interface [polypeptide binding]; other site
929556007228	5S rRNA interface [nucleotide binding]; other site
929556007229	L27 interface [polypeptide binding]; other site
929556007230	L5 interface [polypeptide binding]; other site
929556007231	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
929556007232	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
929556007233	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
929556007234	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
929556007235	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
929556007236	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
929556007237	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
929556007238	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
929556007239	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
929556007240	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
929556007241	RNA binding site [nucleotide binding]; other site
929556007242	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
929556007243	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
929556007244	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
929556007245	23S rRNA interface [nucleotide binding]; other site
929556007246	putative translocon interaction site; other site
929556007247	signal recognition particle (SRP54) interaction site; other site
929556007248	L23 interface [polypeptide binding]; other site
929556007249	trigger factor interaction site; other site
929556007250	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
929556007251	23S rRNA interface [nucleotide binding]; other site
929556007252	5S rRNA interface [nucleotide binding]; other site
929556007253	putative antibiotic binding site [chemical binding]; other site
929556007254	L25 interface [polypeptide binding]; other site
929556007255	L27 interface [polypeptide binding]; other site
929556007256	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
929556007257	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
929556007258	G-X-X-G motif; other site
929556007259	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
929556007260	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
929556007261	putative translocon binding site; other site
929556007262	protein-rRNA interface [nucleotide binding]; other site
929556007263	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
929556007264	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
929556007265	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
929556007266	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
929556007267	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
929556007268	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
929556007269	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
929556007270	Protein of unknown function (DUF3308); Region: DUF3308; cl14675
929556007271	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556007272	Domain of unknown function DUF11; Region: DUF11; pfam01345
929556007273	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556007274	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
929556007275	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556007276	active site
929556007277	phosphorylation site [posttranslational modification]
929556007278	intermolecular recognition site; other site
929556007279	dimerization interface [polypeptide binding]; other site
929556007280	LytTr DNA-binding domain; Region: LytTR; smart00850
929556007281	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
929556007282	Histidine kinase; Region: HisKA_2; pfam07568
929556007283	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556007284	ATP binding site [chemical binding]; other site
929556007285	Mg2+ binding site [ion binding]; other site
929556007286	G-X-G motif; other site
929556007287	Integrase core domain; Region: rve; pfam00665
929556007288	Integrase core domain; Region: rve_3; pfam13683
929556007289	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
929556007290	elongation factor G; Reviewed; Region: PRK12739
929556007291	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
929556007292	G1 box; other site
929556007293	putative GEF interaction site [polypeptide binding]; other site
929556007294	GTP/Mg2+ binding site [chemical binding]; other site
929556007295	Switch I region; other site
929556007296	G2 box; other site
929556007297	G3 box; other site
929556007298	Switch II region; other site
929556007299	G4 box; other site
929556007300	G5 box; other site
929556007301	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
929556007302	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
929556007303	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
929556007304	30S ribosomal protein S7; Validated; Region: PRK05302
929556007305	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
929556007306	S17 interaction site [polypeptide binding]; other site
929556007307	S8 interaction site; other site
929556007308	16S rRNA interaction site [nucleotide binding]; other site
929556007309	streptomycin interaction site [chemical binding]; other site
929556007310	23S rRNA interaction site [nucleotide binding]; other site
929556007311	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
929556007312	Esterase/lipase [General function prediction only]; Region: COG1647
929556007313	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
929556007314	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
929556007315	active site
929556007316	dimer interface [polypeptide binding]; other site
929556007317	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
929556007318	dimer interface [polypeptide binding]; other site
929556007319	active site
929556007320	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
929556007321	putative active site [active]
929556007322	catalytic residue [active]
929556007323	Integrase core domain; Region: rve; pfam00665
929556007324	Integrase core domain; Region: rve_3; pfam13683
929556007325	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
929556007326	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
929556007327	5S rRNA interface [nucleotide binding]; other site
929556007328	CTC domain interface [polypeptide binding]; other site
929556007329	L16 interface [polypeptide binding]; other site
929556007330	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
929556007331	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
929556007332	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929556007333	active site
929556007334	Protein of unknown function (DUF2723); Region: DUF2723; pfam11028
929556007335	Protein of unknown function (DUF2723); Region: DUF2723; pfam11028
929556007336	Exonuclease-Endonuclease-Phosphatase domain; uncharacterized family 1; Region: EEP-1; cd09083
929556007337	putative catalytic site [active]
929556007338	putative metal binding site [ion binding]; other site
929556007339	putative phosphate binding site [ion binding]; other site
929556007340	Predicted periplasmic or secreted lipoprotein [General function prediction only]; Region: OsmY; COG2823
929556007341	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
929556007342	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
929556007343	Uncharacterized conserved protein [Function unknown]; Region: COG3189
929556007344	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
929556007345	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
929556007346	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
929556007347	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556007348	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556007349	DNA binding residues [nucleotide binding]
929556007350	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
929556007351	FecR protein; Region: FecR; pfam04773
929556007352	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556007353	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556007354	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
929556007355	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556007356	starch binding outer membrane protein SusD; Region: SusD; cl17845
929556007357	Domain of unknown function (DUF4302); Region: DUF4302; pfam14135
929556007358	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
929556007359	Sel1 repeat; Region: Sel1; pfam08238
929556007360	Sel1-like repeats; Region: SEL1; smart00671
929556007361	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
929556007362	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
929556007363	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
929556007364	substrate binding pocket [chemical binding]; other site
929556007365	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556007366	membrane ATPase/protein kinase; Provisional; Region: PRK09435
929556007367	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
929556007368	Walker A; other site
929556007369	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
929556007370	G4 box; other site
929556007371	G5 box; other site
929556007372	Methylmalonyl-CoA epimerase (MMCE); Region: MMCE; cd07249
929556007373	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556007374	dimer interface [polypeptide binding]; other site
929556007375	substrate binding site [chemical binding]; other site
929556007376	metal binding site [ion binding]; metal-binding site
929556007377	methylmalonyl-CoA decarboxylase alpha subunit; Region: mmdA; TIGR01117
929556007378	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
929556007379	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
929556007380	putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK05641
929556007381	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
929556007382	carboxyltransferase (CT) interaction site; other site
929556007383	biotinylation site [posttranslational modification]; other site
929556007384	Integral membrane protein TerC family; Region: TerC; cl10468
929556007385	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit [Energy production and conversion]; Region: OadB; COG1883
929556007386	butyryl-CoA:acetate CoA-transferase; Region: butyr_acet_CoA; TIGR03948
929556007387	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
929556007388	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
929556007389	methylmalonyl-CoA mutase, heterodimeric type, beta chain; Region: mmCoA_mut_beta; TIGR00642
929556007390	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Beta subunit-like subfamily; contains bacterial proteins similar to the beta subunit of MCMs from Propionbacterium shermanni and Streptomyces cinnamonensis, which are alpha/beta...; Region: MM_CoA_mutase_beta; cd03677
929556007391	heterodimer interface [polypeptide binding]; other site
929556007392	substrate interaction site [chemical binding]; other site
929556007393	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
929556007394	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
929556007395	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
929556007396	active site
929556007397	substrate binding site [chemical binding]; other site
929556007398	coenzyme B12 binding site [chemical binding]; other site
929556007399	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
929556007400	B12 binding site [chemical binding]; other site
929556007401	cobalt ligand [ion binding]; other site
929556007402	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
929556007403	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; cl01747
929556007404	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556007405	Ribokinase-like subgroup C.  Found only in bacteria, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_C; cd01946
929556007406	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
929556007407	substrate binding site [chemical binding]; other site
929556007408	ATP binding site [chemical binding]; other site
929556007409	Cytochrome b5-like Heme/Steroid binding domain; Region: Cyt-b5; cl02041
929556007410	Apolipoprotein A1/A4/E domain; Region: Apolipoprotein; pfam01442
929556007411	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
929556007412	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556007413	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556007414	DNA binding residues [nucleotide binding]
929556007415	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
929556007416	FAD binding domain; Region: FAD_binding_4; pfam01565
929556007417	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
929556007418	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
929556007419	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
929556007420	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
929556007421	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
929556007422	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929556007423	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
929556007424	FOG: CBS domain [General function prediction only]; Region: COG0517
929556007425	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_10; cd04623
929556007426	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; Region: Oxidored_q4; cl00535
929556007427	NADH dehydrogenase subunit B; Validated; Region: PRK06411
929556007428	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
929556007429	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
929556007430	NADH dehydrogenase subunit D; Validated; Region: PRK06075
929556007431	NADH dehydrogenase subunit E; Validated; Region: PRK07539
929556007432	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
929556007433	putative dimer interface [polypeptide binding]; other site
929556007434	[2Fe-2S] cluster binding site [ion binding]; other site
929556007435	NADH-quinone oxidoreductase, F subunit; Region: nuoF_fam; TIGR01959
929556007436	SLBB domain; Region: SLBB; pfam10531
929556007437	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
929556007438	NADH-quinone oxidoreductase, chain G; Region: NuoG; TIGR01973
929556007439	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
929556007440	catalytic loop [active]
929556007441	iron binding site [ion binding]; other site
929556007442	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
929556007443	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
929556007444	[4Fe-4S] binding site [ion binding]; other site
929556007445	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
929556007446	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
929556007447	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
929556007448	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
929556007449	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
929556007450	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
929556007451	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
929556007452	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
929556007453	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
929556007454	NADH dehydrogenase subunit 5 C-terminus; Region: NADH5_C; pfam06455
929556007455	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
929556007456	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
929556007457	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
929556007458	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
929556007459	Protein of unknown function (DUF3316); Region: DUF3316; pfam11777
929556007460	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
929556007461	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556007462	Walker A/P-loop; other site
929556007463	ATP binding site [chemical binding]; other site
929556007464	Q-loop/lid; other site
929556007465	ABC transporter signature motif; other site
929556007466	Walker B; other site
929556007467	D-loop; other site
929556007468	ABC transporter; Region: ABC_tran_2; pfam12848
929556007469	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
929556007470	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
929556007471	Domain of unknown function (DUF4382); Region: DUF4382; pfam14321
929556007472	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
929556007473	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929556007474	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556007475	active site
929556007476	phosphorylation site [posttranslational modification]
929556007477	intermolecular recognition site; other site
929556007478	dimerization interface [polypeptide binding]; other site
929556007479	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929556007480	DNA binding site [nucleotide binding]
929556007481	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556007482	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556007483	dimer interface [polypeptide binding]; other site
929556007484	phosphorylation site [posttranslational modification]
929556007485	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556007486	ATP binding site [chemical binding]; other site
929556007487	Mg2+ binding site [ion binding]; other site
929556007488	G-X-G motif; other site
929556007489	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
929556007490	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
929556007491	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
929556007492	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
929556007493	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556007494	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
929556007495	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
929556007496	E3 interaction surface; other site
929556007497	lipoyl attachment site [posttranslational modification]; other site
929556007498	e3 binding domain; Region: E3_binding; pfam02817
929556007499	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
929556007500	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
929556007501	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
929556007502	TPP-binding site [chemical binding]; other site
929556007503	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
929556007504	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
929556007505	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
929556007506	DNA binding residues [nucleotide binding]
929556007507	B12 binding domain; Region: B12-binding_2; pfam02607
929556007508	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
929556007509	Putative D-3-Phosphoglycerate Dehydrogenases; Region: PGDH_like_1; cd12169
929556007510	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
929556007511	dimerization interface [polypeptide binding]; other site
929556007512	NAD binding site [chemical binding]; other site
929556007513	ligand binding site [chemical binding]; other site
929556007514	catalytic site [active]
929556007515	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
929556007516	ABC1 family; Region: ABC1; cl17513
929556007517	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
929556007518	active site
929556007519	ATP binding site [chemical binding]; other site
929556007520	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
929556007521	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929556007522	NAD(P) binding site [chemical binding]; other site
929556007523	active site
929556007524	FOG: CBS domain [General function prediction only]; Region: COG0517
929556007525	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_10; cd04623
929556007526	Transposase, Mutator family; Region: Transposase_mut; pfam00872
929556007527	MULE transposase domain; Region: MULE; pfam10551
929556007528	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
929556007529	dimer interface [polypeptide binding]; other site
929556007530	[2Fe-2S] cluster binding site [ion binding]; other site
929556007531	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929556007532	TIGR01777 family protein; Region: yfcH
929556007533	NAD(P) binding site [chemical binding]; other site
929556007534	active site
929556007535	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
929556007536	DNA photolyase; Region: DNA_photolyase; pfam00875
929556007537	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
929556007538	peptidyl-prolyl isomerase, gliding motility-associated; Region: ppisom_GldI; TIGR03516
929556007539	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
929556007540	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
929556007541	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
929556007542	active site
929556007543	acetyl-CoA acetyltransferase; Provisional; Region: PRK09052
929556007544	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
929556007545	dimer interface [polypeptide binding]; other site
929556007546	active site
929556007547	GIY-YIG domain of uncharacterized hypothetical protein found in bacteria; Region: GIY-YIG_unchar_3; cd10448
929556007548	GIY-YIG motif/motif A; other site
929556007549	putative active site [active]
929556007550	putative metal binding site [ion binding]; other site
929556007551	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
929556007552	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
929556007553	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
929556007554	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
929556007555	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
929556007556	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
929556007557	substrate binding site [chemical binding]; other site
929556007558	oxyanion hole (OAH) forming residues; other site
929556007559	trimer interface [polypeptide binding]; other site
929556007560	Transcriptional regulators [Transcription]; Region: MarR; COG1846
929556007561	MarR family; Region: MarR_2; pfam12802
929556007562	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
929556007563	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
929556007564	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
929556007565	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
929556007566	acyl-activating enzyme (AAE) consensus motif; other site
929556007567	putative AMP binding site [chemical binding]; other site
929556007568	putative active site [active]
929556007569	putative CoA binding site [chemical binding]; other site
929556007570	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
929556007571	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
929556007572	acyl-activating enzyme (AAE) consensus motif; other site
929556007573	putative AMP binding site [chemical binding]; other site
929556007574	putative active site [active]
929556007575	putative CoA binding site [chemical binding]; other site
929556007576	Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070
929556007577	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
929556007578	FMN binding site [chemical binding]; other site
929556007579	substrate binding site [chemical binding]; other site
929556007580	putative catalytic residue [active]
929556007581	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
929556007582	CoenzymeA binding site [chemical binding]; other site
929556007583	subunit interaction site [polypeptide binding]; other site
929556007584	PHB binding site; other site
929556007585	Low molecular weight phosphatase family; Region: LMWPc; cl00105
929556007586	active site
929556007587	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
929556007588	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
929556007589	putative active site [active]
929556007590	putative metal binding site [ion binding]; other site
929556007591	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
929556007592	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
929556007593	Potassium binding sites [ion binding]; other site
929556007594	Cesium cation binding sites [ion binding]; other site
929556007595	Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975
929556007596	M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299
929556007597	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
929556007598	protein binding site [polypeptide binding]; other site
929556007599	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4102
929556007600	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
929556007601	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
929556007602	Protein of unknown function (DUF1800); Region: DUF1800; pfam08811
929556007603	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
929556007604	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
929556007605	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556007606	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
929556007607	Protein export membrane protein; Region: SecD_SecF; cl14618
929556007608	Outer membrane efflux protein; Region: OEP; pfam02321
929556007609	Outer membrane efflux protein; Region: OEP; pfam02321
929556007610	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556007611	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
929556007612	active site
929556007613	phosphorylation site [posttranslational modification]
929556007614	intermolecular recognition site; other site
929556007615	dimerization interface [polypeptide binding]; other site
929556007616	Peptidase S8 family domain in Kp43 proteases; Region: Peptidases_S8_Kp43_protease; cd04842
929556007617	active site
929556007618	catalytic triad [active]
929556007619	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
929556007620	Right handed beta helix region; Region: Beta_helix; pfam13229
929556007621	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
929556007622	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
929556007623	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
929556007624	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
929556007625	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
929556007626	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
929556007627	inhibitor-cofactor binding pocket; inhibition site
929556007628	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556007629	catalytic residue [active]
929556007630	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
929556007631	putative trimer interface [polypeptide binding]; other site
929556007632	putative active site [active]
929556007633	putative substrate binding site [chemical binding]; other site
929556007634	putative CoA binding site [chemical binding]; other site
929556007635	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
929556007636	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
929556007637	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
929556007638	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
929556007639	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
929556007640	Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily; Region: CE4_u7; cd10931
929556007641	putative active site [active]
929556007642	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; cl17497
929556007643	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
929556007644	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
929556007645	O-Antigen ligase; Region: Wzy_C; pfam04932
929556007646	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
929556007647	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
929556007648	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
929556007649	Chain length determinant protein; Region: Wzz; pfam02706
929556007650	exopolysaccharide transport protein family; Region: eps_transp_fam; TIGR01005
929556007651	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
929556007652	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
929556007653	SLBB domain; Region: SLBB; pfam10531
929556007654	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
929556007655	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
929556007656	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556007657	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556007658	DNA binding residues [nucleotide binding]
929556007659	NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282
929556007660	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
929556007661	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
929556007662	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
929556007663	NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288
929556007664	ligand binding site [chemical binding]; other site
929556007665	homodimer interface [polypeptide binding]; other site
929556007666	NAD(P) binding site [chemical binding]; other site
929556007667	trimer interface B [polypeptide binding]; other site
929556007668	trimer interface A [polypeptide binding]; other site
929556007669	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
929556007670	Transposase; Region: DDE_Tnp_ISL3; pfam01610
929556007671	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
929556007672	Transposase; Region: DDE_Tnp_ISL3; pfam01610
929556007673	GTPase Era; Reviewed; Region: era; PRK00089
929556007674	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
929556007675	G1 box; other site
929556007676	GTP/Mg2+ binding site [chemical binding]; other site
929556007677	Switch I region; other site
929556007678	G2 box; other site
929556007679	Switch II region; other site
929556007680	G3 box; other site
929556007681	G4 box; other site
929556007682	G5 box; other site
929556007683	KH domain; Region: KH_2; pfam07650
929556007684	GTP-binding protein Der; Reviewed; Region: PRK00093
929556007685	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
929556007686	G1 box; other site
929556007687	GTP/Mg2+ binding site [chemical binding]; other site
929556007688	Switch I region; other site
929556007689	G2 box; other site
929556007690	Switch II region; other site
929556007691	G3 box; other site
929556007692	G4 box; other site
929556007693	G5 box; other site
929556007694	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
929556007695	G1 box; other site
929556007696	GTP/Mg2+ binding site [chemical binding]; other site
929556007697	Switch I region; other site
929556007698	G2 box; other site
929556007699	G3 box; other site
929556007700	Switch II region; other site
929556007701	G4 box; other site
929556007702	G5 box; other site
929556007703	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
929556007704	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
929556007705	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
929556007706	protein binding site [polypeptide binding]; other site
929556007707	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
929556007708	Catalytic dyad [active]
929556007709	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
929556007710	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
929556007711	putative active site [active]
929556007712	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
929556007713	PhoU domain; Region: PhoU; pfam01895
929556007714	PhoU domain; Region: PhoU; pfam01895
929556007715	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
929556007716	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
929556007717	Walker A/P-loop; other site
929556007718	ATP binding site [chemical binding]; other site
929556007719	Q-loop/lid; other site
929556007720	ABC transporter signature motif; other site
929556007721	Walker B; other site
929556007722	D-loop; other site
929556007723	H-loop/switch region; other site
929556007724	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
929556007725	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929556007726	dimer interface [polypeptide binding]; other site
929556007727	conserved gate region; other site
929556007728	putative PBP binding loops; other site
929556007729	ABC-ATPase subunit interface; other site
929556007730	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
929556007731	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929556007732	dimer interface [polypeptide binding]; other site
929556007733	conserved gate region; other site
929556007734	putative PBP binding loops; other site
929556007735	ABC-ATPase subunit interface; other site
929556007736	phosphate binding protein; Region: ptsS_2; TIGR02136
929556007737	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
929556007738	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
929556007739	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
929556007740	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
929556007741	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
929556007742	glycerol kinase; Provisional; Region: glpK; PRK00047
929556007743	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
929556007744	N- and C-terminal domain interface [polypeptide binding]; other site
929556007745	active site
929556007746	MgATP binding site [chemical binding]; other site
929556007747	catalytic site [active]
929556007748	metal binding site [ion binding]; metal-binding site
929556007749	glycerol binding site [chemical binding]; other site
929556007750	homotetramer interface [polypeptide binding]; other site
929556007751	homodimer interface [polypeptide binding]; other site
929556007752	FBP binding site [chemical binding]; other site
929556007753	protein IIAGlc interface [polypeptide binding]; other site
929556007754	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
929556007755	amphipathic channel; other site
929556007756	Asn-Pro-Ala signature motifs; other site
929556007757	YceI-like domain; Region: YceI; cl01001
929556007758	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556007759	YceI-like domain; Region: YceI; pfam04264
929556007760	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
929556007761	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
929556007762	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
929556007763	substrate binding pocket [chemical binding]; other site
929556007764	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
929556007765	B12 binding site [chemical binding]; other site
929556007766	cobalt ligand [ion binding]; other site
929556007767	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
929556007768	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
929556007769	FAD binding site [chemical binding]; other site
929556007770	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_1; cd07818
929556007771	putative hydrophobic ligand binding site [chemical binding]; other site
929556007772	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
929556007773	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
929556007774	Ligand binding site; other site
929556007775	Putative Catalytic site; other site
929556007776	DXD motif; other site
929556007777	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
929556007778	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
929556007779	GTPase RsgA; Reviewed; Region: PRK00098
929556007780	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
929556007781	RNA binding site [nucleotide binding]; other site
929556007782	homodimer interface [polypeptide binding]; other site
929556007783	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
929556007784	GTPase/Zn-binding domain interface [polypeptide binding]; other site
929556007785	GTP/Mg2+ binding site [chemical binding]; other site
929556007786	G4 box; other site
929556007787	G5 box; other site
929556007788	G1 box; other site
929556007789	Switch I region; other site
929556007790	G2 box; other site
929556007791	G3 box; other site
929556007792	Switch II region; other site
929556007793	Serine hydrolase; Region: Ser_hydrolase; pfam06821
929556007794	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
929556007795	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
929556007796	putative active site [active]
929556007797	dimerization interface [polypeptide binding]; other site
929556007798	putative tRNAtyr binding site [nucleotide binding]; other site
929556007799	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs; Region: NTP-PPase_BsYpjD; cd11531
929556007800	homodimer interface [polypeptide binding]; other site
929556007801	metal binding site [ion binding]; metal-binding site
929556007802	2-phosphosulpholactate phosphatase; Region: 2-ph_phosp; pfam04029
929556007803	Phosphosulfolactate phosphohydrolase and related enzymes [Coenzyme metabolism / General function prediction only]; Region: COG2045
929556007804	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
929556007805	Sarcosine oxidase, gamma subunit family; Region: SoxG; cl01893
929556007806	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
929556007807	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
929556007808	RNA/DNA hybrid binding site [nucleotide binding]; other site
929556007809	active site
929556007810	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
929556007811	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
929556007812	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
929556007813	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
929556007814	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929556007815	dimer interface [polypeptide binding]; other site
929556007816	conserved gate region; other site
929556007817	putative PBP binding loops; other site
929556007818	ABC-ATPase subunit interface; other site
929556007819	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
929556007820	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_e; cd04192
929556007821	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
929556007822	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
929556007823	active site
929556007824	putative DNA-binding cleft [nucleotide binding]; other site
929556007825	dimer interface [polypeptide binding]; other site
929556007826	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
929556007827	nucleotide binding site/active site [active]
929556007828	HIT family signature motif; other site
929556007829	catalytic residue [active]
929556007830	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
929556007831	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
929556007832	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
929556007833	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
929556007834	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
929556007835	NAD binding site [chemical binding]; other site
929556007836	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
929556007837	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556007838	S-adenosylmethionine binding site [chemical binding]; other site
929556007839	4-hydroxythreonine-4-phosphate dehydrogenase; Region: pdxA; TIGR00557
929556007840	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
929556007841	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
929556007842	nucleoside/Zn binding site; other site
929556007843	dimer interface [polypeptide binding]; other site
929556007844	catalytic motif [active]
929556007845	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
929556007846	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
929556007847	active site
929556007848	catalytic site [active]
929556007849	Protein of unknown function (DUF3078); Region: DUF3078; pfam11276
929556007850	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
929556007851	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
929556007852	TPP-binding site [chemical binding]; other site
929556007853	tetramer interface [polypeptide binding]; other site
929556007854	heterodimer interface [polypeptide binding]; other site
929556007855	phosphorylation loop region [posttranslational modification]
929556007856	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
929556007857	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
929556007858	alpha subunit interface [polypeptide binding]; other site
929556007859	TPP binding site [chemical binding]; other site
929556007860	heterodimer interface [polypeptide binding]; other site
929556007861	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
929556007862	MG2 domain; Region: A2M_N; pfam01835
929556007863	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
929556007864	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556007865	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
929556007866	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
929556007867	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_2; cd03402
929556007868	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4877
929556007869	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
929556007870	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
929556007871	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
929556007872	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
929556007873	M28 Zn-Peptidases containing a PA domain insert; Region: M28_like_PA; cd03877
929556007874	Peptidase family M28; Region: Peptidase_M28; pfam04389
929556007875	metal binding site [ion binding]; metal-binding site
929556007876	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
929556007877	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
929556007878	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
929556007879	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
929556007880	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
929556007881	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
929556007882	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
929556007883	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
929556007884	carboxyltransferase (CT) interaction site; other site
929556007885	biotinylation site [posttranslational modification]; other site
929556007886	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
929556007887	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
929556007888	dimer interface [polypeptide binding]; other site
929556007889	active site
929556007890	CoA binding pocket [chemical binding]; other site
929556007891	putative phosphate acyltransferase; Provisional; Region: PRK05331
929556007892	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
929556007893	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
929556007894	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
929556007895	catalytic nucleophile [active]
929556007896	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
929556007897	dimer interface [polypeptide binding]; other site
929556007898	ADP-ribose binding site [chemical binding]; other site
929556007899	active site
929556007900	nudix motif; other site
929556007901	metal binding site [ion binding]; metal-binding site
929556007902	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
929556007903	active site
929556007904	dimerization interface [polypeptide binding]; other site
929556007905	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
929556007906	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
929556007907	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
929556007908	MoxR-like ATPases [General function prediction only]; Region: COG0714
929556007909	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556007910	Walker A motif; other site
929556007911	ATP binding site [chemical binding]; other site
929556007912	Walker B motif; other site
929556007913	arginine finger; other site
929556007914	Transposase, Mutator family; Region: Transposase_mut; pfam00872
929556007915	MULE transposase domain; Region: MULE; pfam10551
929556007916	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
929556007917	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
929556007918	active site
929556007919	catalytic residues [active]
929556007920	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
929556007921	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556007922	catalytic residues [active]
929556007923	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556007924	SusD family; Region: SusD; pfam07980
929556007925	Secretin and TonB N terminus short domain; Region: STN; smart00965
929556007926	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556007927	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556007928	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556007929	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
929556007930	Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712
929556007931	FecR protein; Region: FecR; pfam04773
929556007932	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
929556007933	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556007934	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556007935	DNA binding residues [nucleotide binding]
929556007936	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
929556007937	DNA-binding site [nucleotide binding]; DNA binding site
929556007938	RNA-binding motif; other site
929556007939	OstA-like protein; Region: OstA_2; pfam13100
929556007940	OstA-like protein; Region: OstA; cl00844
929556007941	OstA-like protein; Region: OstA_2; pfam13100
929556007942	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
929556007943	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
929556007944	Ligand Binding Site [chemical binding]; other site
929556007945	TilS substrate C-terminal domain; Region: TilS_C; smart00977
929556007946	Predicted naringenin-chalcone synthase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BcsA; COG3424
929556007947	Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, also called type III PKSs. PKS generate an array of different products, dependent on the nature of the starter molecule. They share a common chemical strategy; Region: CHS_like; cd00831
929556007948	malonyl-CoA binding site [chemical binding]; other site
929556007949	dimer interface [polypeptide binding]; other site
929556007950	active site
929556007951	product binding site; other site
929556007952	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
929556007953	2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654
929556007954	pyruvate carboxylase; Reviewed; Region: PRK12999
929556007955	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
929556007956	ATP-grasp domain; Region: ATP-grasp_4; cl17255
929556007957	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
929556007958	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
929556007959	active site
929556007960	catalytic residues [active]
929556007961	metal binding site [ion binding]; metal-binding site
929556007962	homodimer binding site [polypeptide binding]; other site
929556007963	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
929556007964	carboxyltransferase (CT) interaction site; other site
929556007965	biotinylation site [posttranslational modification]; other site
929556007966	seryl-tRNA synthetase; Provisional; Region: PRK05431
929556007967	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
929556007968	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
929556007969	dimer interface [polypeptide binding]; other site
929556007970	active site
929556007971	motif 1; other site
929556007972	motif 2; other site
929556007973	motif 3; other site
929556007974	Predicted methyltransferases [General function prediction only]; Region: COG0313
929556007975	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
929556007976	putative SAM binding site [chemical binding]; other site
929556007977	putative homodimer interface [polypeptide binding]; other site
929556007978	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
929556007979	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
929556007980	putative active site [active]
929556007981	catalytic triad [active]
929556007982	putative dimer interface [polypeptide binding]; other site
929556007983	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
929556007984	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
929556007985	nucleotide binding site [chemical binding]; other site
929556007986	NAD synthetase; Provisional; Region: PRK13981
929556007987	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
929556007988	multimer interface [polypeptide binding]; other site
929556007989	active site
929556007990	catalytic triad [active]
929556007991	protein interface 1 [polypeptide binding]; other site
929556007992	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
929556007993	homodimer interface [polypeptide binding]; other site
929556007994	NAD binding pocket [chemical binding]; other site
929556007995	ATP binding pocket [chemical binding]; other site
929556007996	Mg binding site [ion binding]; other site
929556007997	active-site loop [active]
929556007998	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
929556007999	gliding motility-associated lipoprotein GldB; Region: GldB_lipo; TIGR03514
929556008000	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
929556008001	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
929556008002	active site
929556008003	nucleophile elbow; other site
929556008004	Protein of unknown function (DUF964); Region: DUF964; cl01483
929556008005	methionine sulfoxide reductase B; Provisional; Region: PRK00222
929556008006	SelR domain; Region: SelR; pfam01641
929556008007	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
929556008008	Phosphoenolpyruvate carboxylase; Region: PEPcase; cl17418
929556008009	Phosphoesterase family; Region: Phosphoesterase; pfam04185
929556008010	Phosphoesterase family; Region: Phosphoesterase; pfam04185
929556008011	Domain of unknown function (DUF756); Region: DUF756; pfam05506
929556008012	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
929556008013	core domain interface [polypeptide binding]; other site
929556008014	delta subunit interface [polypeptide binding]; other site
929556008015	epsilon subunit interface [polypeptide binding]; other site
929556008016	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
929556008017	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
929556008018	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
929556008019	beta subunit interaction interface [polypeptide binding]; other site
929556008020	Walker A motif; other site
929556008021	ATP binding site [chemical binding]; other site
929556008022	Walker B motif; other site
929556008023	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
929556008024	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
929556008025	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
929556008026	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
929556008027	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
929556008028	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
929556008029	ATP synthase A chain; Region: ATP-synt_A; cl00413
929556008030	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
929556008031	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
929556008032	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
929556008033	Peptidase family M23; Region: Peptidase_M23; pfam01551
929556008034	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556008035	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
929556008036	Transglycosylase; Region: Transgly; pfam00912
929556008037	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
929556008038	oxidase reductase; Provisional; Region: PTZ00273
929556008039	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
929556008040	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
929556008041	Dienelactone hydrolase family; Region: DLH; pfam01738
929556008042	Glycoside hydrolase 97; Region: Glyco_hydro_97; pfam10566
929556008043	Recombination protein O N terminal; Region: RecO_N; pfam11967
929556008044	Recombination protein O C terminal; Region: RecO_C; pfam02565
929556008045	Predicted exporters of the RND superfamily [General function prediction only]; Region: COG1033
929556008046	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
929556008047	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929556008048	non-specific DNA binding site [nucleotide binding]; other site
929556008049	salt bridge; other site
929556008050	sequence-specific DNA binding site [nucleotide binding]; other site
929556008051	isoleucyl-tRNA synthetase; Region: ileS; TIGR00392
929556008052	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
929556008053	active site
929556008054	HIGH motif; other site
929556008055	nucleotide binding site [chemical binding]; other site
929556008056	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
929556008057	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
929556008058	active site
929556008059	KMSKS motif; other site
929556008060	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
929556008061	tRNA binding surface [nucleotide binding]; other site
929556008062	anticodon binding site; other site
929556008063	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
929556008064	lipoprotein signal peptidase; Provisional; Region: PRK14788
929556008065	lipoprotein signal peptidase; Provisional; Region: PRK14787
929556008066	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
929556008067	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
929556008068	Uncharacterized conserved protein [Function unknown]; Region: COG2968
929556008069	Protein of unknown function (DUF541); Region: SIMPL; pfam04402
929556008070	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
929556008071	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
929556008072	GIY-YIG motif/motif A; other site
929556008073	active site
929556008074	catalytic site [active]
929556008075	putative DNA binding site [nucleotide binding]; other site
929556008076	metal binding site [ion binding]; metal-binding site
929556008077	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
929556008078	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
929556008079	DNA binding site [nucleotide binding]
929556008080	gliding motility associated protien GldN; Region: GldN; TIGR03523
929556008081	gliding motility-associated protein GldM; Region: GldM_gliding; TIGR03517
929556008082	GldM N-terminal domain; Region: GldM_N; pfam12081
929556008083	GldM C-terminal domain; Region: GldM_C; pfam12080
929556008084	gliding motility-associated protein GldL; Region: GldL_gliding; TIGR03513
929556008085	gliding motility-associated lipoprotein GldK; Region: GldK; TIGR03525
929556008086	gliding motility-associated lipoprotein GldJ; Region: GldJ; TIGR03524
929556008087	gliding motility-associated lipoprotein GldJ; Region: GldJ; TIGR03524
929556008088	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
929556008089	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
929556008090	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
929556008091	active site
929556008092	Domain of unknown function (DUF4271); Region: DUF4271; pfam14093
929556008093	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07666
929556008094	classical (c) SDRs; Region: SDR_c; cd05233
929556008095	NAD(P) binding site [chemical binding]; other site
929556008096	active site
929556008097	TraB family; Region: TraB; pfam01963
929556008098	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
929556008099	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556008100	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556008101	DNA binding residues [nucleotide binding]
929556008102	Coproporphyrinogen III oxidase and related Fe-S oxidoreductases [Coenzyme metabolism]; Region: HemN; COG0635
929556008103	HemN C-terminal domain; Region: HemN_C; pfam06969
929556008104	Cupin-like domain; Region: Cupin_8; pfam13621
929556008105	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556008106	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556008107	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556008108	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556008109	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556008110	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
929556008111	metal ion-dependent adhesion site (MIDAS); other site
929556008112	Mg-chelatase subunit ChlI [Coenzyme metabolism]; Region: ChlI; COG1239
929556008113	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
929556008114	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556008115	Coenzyme A binding pocket [chemical binding]; other site
929556008116	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
929556008117	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556008118	Coenzyme A binding pocket [chemical binding]; other site
929556008119	phosphodiesterase YaeI; Provisional; Region: PRK11340
929556008120	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
929556008121	putative active site [active]
929556008122	putative metal binding site [ion binding]; other site
929556008123	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
929556008124	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
929556008125	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
929556008126	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
929556008127	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
929556008128	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
929556008129	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929556008130	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556008131	active site
929556008132	phosphorylation site [posttranslational modification]
929556008133	intermolecular recognition site; other site
929556008134	dimerization interface [polypeptide binding]; other site
929556008135	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929556008136	DNA binding site [nucleotide binding]
929556008137	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556008138	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556008139	dimer interface [polypeptide binding]; other site
929556008140	phosphorylation site [posttranslational modification]
929556008141	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556008142	ATP binding site [chemical binding]; other site
929556008143	Mg2+ binding site [ion binding]; other site
929556008144	G-X-G motif; other site
929556008145	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
929556008146	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556008147	MoeA N-terminal region (domain I and II); Region: MoeA_N; pfam03453
929556008148	MoCF_BD: molybdenum cofactor (MoCF) binding domain (BD). This domain is found a variety of proteins involved in biosynthesis of molybdopterin cofactor, like MoaB, MogA, and MoeA. The domain is presumed to bind molybdopterin; Region: MoCF_BD; cl00451
929556008149	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
929556008150	Thermus thermophiles TTHB029 and similar proteins; Region: YdjC_TTHB029_like; cd10802
929556008151	putative active site [active]
929556008152	YdjC motif; other site
929556008153	Mg binding site [ion binding]; other site
929556008154	homodimer interface [polypeptide binding]; other site
929556008155	Domain of unknown function (DUF4286); Region: DUF4286; pfam14114
929556008156	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
929556008157	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
929556008158	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556008159	ligand binding site [chemical binding]; other site
929556008160	Conserved hypothetical protein (DUF2461); Region: DUF2461; pfam09365
929556008161	Protein of unknown function (DUF420); Region: DUF420; pfam04238
929556008162	Predicted small integral membrane protein [Function unknown]; Region: COG5605
929556008163	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211
929556008164	Subunit I/III interface [polypeptide binding]; other site
929556008165	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211
929556008166	Subunit I/III interface [polypeptide binding]; other site
929556008167	protoheme IX farnesyltransferase; Region: cyoE_ctaB; TIGR01473
929556008168	UbiA prenyltransferase family; Region: UbiA; pfam01040
929556008169	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
929556008170	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
929556008171	cytochrome c oxidase, subunit I; Region: CtaD_CoxA; TIGR02891
929556008172	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
929556008173	Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion]; Region: CyoA; COG1622
929556008174	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
929556008175	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
929556008176	Protein of unknown function (DUF3341); Region: DUF3341; pfam11821
929556008177	Polysulphide reductase [Energy production and conversion]; Region: COG5557; cl17901
929556008178	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
929556008179	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
929556008180	molybdopterin cofactor binding site; other site
929556008181	The MopB_CT_PHLH CD includes a group of related uncharacterized putative hydrogenase-like homologs (PHLH) of molybdopterin binding proteins. This CD is of the PHLH region homologous to the conserved molybdopterin-binding C-terminal (MopB_CT) region...; Region: MopB_CT_PHLH; cd02784
929556008182	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
929556008183	4Fe-4S binding domain; Region: Fer4; cl02805
929556008184	Cytochrome c; Region: Cytochrom_C; cl11414
929556008185	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
929556008186	Heme-binding domain of the class III cytochrome C family and related proteins; Region: Cytochrom_C3; cd08168
929556008187	heme-binding residues [chemical binding]; other site
929556008188	deoxyhypusine synthase; Region: dhys; TIGR00321
929556008189	Deoxyhypusine synthase; Region: DS; cl00826
929556008190	Deoxyhypusine synthase; Region: DS; cl00826
929556008191	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
929556008192	starch binding outer membrane protein SusD; Region: SusD; cl17845
929556008193	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556008194	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556008195	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556008196	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556008197	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
929556008198	starch binding outer membrane protein SusD; Region: SusD; cl17845
929556008199	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556008200	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556008201	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556008202	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
929556008203	Surface antigen; Region: Bac_surface_Ag; pfam01103
929556008204	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556008205	S-adenosylmethionine binding site [chemical binding]; other site
929556008206	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
929556008207	peptide chain release factor 2; Validated; Region: prfB; PRK00578
929556008208	PCRF domain; Region: PCRF; pfam03462
929556008209	RF-1 domain; Region: RF-1; pfam00472
929556008210	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
929556008211	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
929556008212	Putative zinc ribbon domain; Region: DUF164; pfam02591
929556008213	Uncharacterized conserved protein [Function unknown]; Region: COG0327
929556008214	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
929556008215	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
929556008216	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
929556008217	Putative methyltransferase; Region: Methyltransf_4; cl17290
929556008218	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
929556008219	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
929556008220	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
929556008221	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
929556008222	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
929556008223	P-loop; other site
929556008224	Magnesium ion binding site [ion binding]; other site
929556008225	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
929556008226	Magnesium ion binding site [ion binding]; other site
929556008227	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
929556008228	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
929556008229	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929556008230	ATP binding site [chemical binding]; other site
929556008231	putative Mg++ binding site [ion binding]; other site
929556008232	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929556008233	nucleotide binding region [chemical binding]; other site
929556008234	ATP-binding site [chemical binding]; other site
929556008235	TRCF domain; Region: TRCF; pfam03461
929556008236	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
929556008237	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
929556008238	active site
929556008239	catalytic residues [active]
929556008240	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929556008241	active site
929556008242	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
929556008243	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
929556008244	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
929556008245	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
929556008246	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556008247	S-adenosylmethionine binding site [chemical binding]; other site
929556008248	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
929556008249	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
929556008250	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
929556008251	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
929556008252	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
929556008253	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
929556008254	active site
929556008255	(T/H)XGH motif; other site
929556008256	Guanylate kinase; Region: Guanylate_kin; pfam00625
929556008257	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
929556008258	catalytic site [active]
929556008259	G-X2-G-X-G-K; other site
929556008260	hypothetical protein; Provisional; Region: PRK11820
929556008261	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
929556008262	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
929556008263	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
929556008264	EamA-like transporter family; Region: EamA; pfam00892
929556008265	EamA-like transporter family; Region: EamA; pfam00892
929556008266	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
929556008267	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
929556008268	putative acyl-acceptor binding pocket; other site
929556008269	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
929556008270	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
929556008271	dimerization interface [polypeptide binding]; other site
929556008272	active site
929556008273	metal binding site [ion binding]; metal-binding site
929556008274	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
929556008275	dsRNA binding site [nucleotide binding]; other site
929556008276	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
929556008277	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
929556008278	dimer interface [polypeptide binding]; other site
929556008279	active site
929556008280	acyl carrier protein; Provisional; Region: acpP; PRK00982
929556008281	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
929556008282	Pyruvate kinase [Carbohydrate transport and metabolism]; Region: PykF; COG0469
929556008283	domain interfaces; other site
929556008284	active site
929556008285	Class II vitamin B12-dependent ribonucleotide reductase; Region: Ribonuc_red_2_N; pfam08471
929556008286	Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888
929556008287	active site
929556008288	dimer interface [polypeptide binding]; other site
929556008289	effector binding site; other site
929556008290	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
929556008291	TSCPD domain; Region: TSCPD; pfam12637
929556008292	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
929556008293	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
929556008294	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
929556008295	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
929556008296	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
929556008297	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
929556008298	hydrophobic ligand binding site; other site
929556008299	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
929556008300	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
929556008301	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556008302	catalytic residues [active]
929556008303	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
929556008304	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556008305	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556008306	Secretin and TonB N terminus short domain; Region: STN; pfam07660
929556008307	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556008308	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556008309	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
929556008310	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
929556008311	FecR protein; Region: FecR; pfam04773
929556008312	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
929556008313	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556008314	DNA binding residues [nucleotide binding]
929556008315	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
929556008316	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
929556008317	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
929556008318	Part of AAA domain; Region: AAA_19; pfam13245
929556008319	Family description; Region: UvrD_C_2; pfam13538
929556008320	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
929556008321	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
929556008322	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
929556008323	alpha subunit interface [polypeptide binding]; other site
929556008324	TPP binding site [chemical binding]; other site
929556008325	heterodimer interface [polypeptide binding]; other site
929556008326	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
929556008327	SmpA / OmlA family; Region: SmpA_OmlA; cl17115
929556008328	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
929556008329	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
929556008330	putative DNA binding site [nucleotide binding]; other site
929556008331	putative Zn2+ binding site [ion binding]; other site
929556008332	AsnC family; Region: AsnC_trans_reg; pfam01037
929556008333	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
929556008334	Amidohydrolase; Region: Amidohydro_4; pfam13147
929556008335	active site
929556008336	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
929556008337	Amidohydrolase; Region: Amidohydro_4; pfam13147
929556008338	active site
929556008339	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
929556008340	Metallo-dependent hydrolases, subgroup C is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_C; cd01309
929556008341	active site
929556008342	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
929556008343	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
929556008344	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
929556008345	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
929556008346	Glutamine amidotransferase class-I; Region: GATase; pfam00117
929556008347	glutamine binding [chemical binding]; other site
929556008348	catalytic triad [active]
929556008349	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
929556008350	active site
929556008351	ribulose/triose binding site [chemical binding]; other site
929556008352	phosphate binding site [ion binding]; other site
929556008353	substrate (anthranilate) binding pocket [chemical binding]; other site
929556008354	product (indole) binding pocket [chemical binding]; other site
929556008355	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
929556008356	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
929556008357	HflX GTPase family; Region: HflX; cd01878
929556008358	G1 box; other site
929556008359	GTP/Mg2+ binding site [chemical binding]; other site
929556008360	Switch I region; other site
929556008361	G2 box; other site
929556008362	G3 box; other site
929556008363	Switch II region; other site
929556008364	G4 box; other site
929556008365	G5 box; other site
929556008366	Uncharacterized subfamily of the tetrapyrrole methylase family similar to ribosomal RNA small subunit methyltransferase I (RsmI); Region: RsmI_like; cd11649
929556008367	putative SAM binding site [chemical binding]; other site
929556008368	homodimer interface [polypeptide binding]; other site
929556008369	CNH domain; Region: CNH; cl02434
929556008370	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
929556008371	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556008372	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556008373	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556008374	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556008375	aspartate aminotransferase; Provisional; Region: PRK05764
929556008376	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
929556008377	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556008378	homodimer interface [polypeptide binding]; other site
929556008379	catalytic residue [active]
929556008380	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556008381	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556008382	SusD family; Region: SusD; pfam07980
929556008383	Secretin and TonB N terminus short domain; Region: STN; pfam07660
929556008384	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556008385	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556008386	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556008387	FecR protein; Region: FecR; pfam04773
929556008388	RNA polymerase sigma-70 factor, Bacteroides expansion family 1; Region: Sig70_bacteroi1; TIGR02985
929556008389	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556008390	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556008391	DNA binding residues [nucleotide binding]
929556008392	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
929556008393	Flavin containing amine oxidoreductase; Region: Amino_oxidase; pfam01593
929556008394	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
929556008395	23S rRNA interface [nucleotide binding]; other site
929556008396	L3 interface [polypeptide binding]; other site
929556008397	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
929556008398	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
929556008399	rRNA interaction site [nucleotide binding]; other site
929556008400	S8 interaction site; other site
929556008401	putative laminin-1 binding site; other site
929556008402	elongation factor Ts; Provisional; Region: tsf; PRK09377
929556008403	UBA/TS-N domain; Region: UBA; pfam00627
929556008404	Elongation factor TS; Region: EF_TS; pfam00889
929556008405	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929556008406	non-specific DNA binding site [nucleotide binding]; other site
929556008407	salt bridge; other site
929556008408	sequence-specific DNA binding site [nucleotide binding]; other site
929556008409	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
929556008410	putative nucleotide binding site [chemical binding]; other site
929556008411	uridine monophosphate binding site [chemical binding]; other site
929556008412	homohexameric interface [polypeptide binding]; other site
929556008413	ribosome recycling factor; Reviewed; Region: frr; PRK00083
929556008414	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
929556008415	hinge region; other site
929556008416	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
929556008417	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
929556008418	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556008419	catalytic residues [active]
929556008420	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556008421	S-adenosylmethionine binding site [chemical binding]; other site
929556008422	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
929556008423	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
929556008424	active site residue [active]
929556008425	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
929556008426	active site residue [active]
929556008427	Methyltransferase domain; Region: Methyltransf_31; pfam13847
929556008428	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556008429	S-adenosylmethionine binding site [chemical binding]; other site
929556008430	Domain of unknown function (DUF4341); Region: DUF4341; pfam14241
929556008431	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
929556008432	Helix-turn-helix domain; Region: HTH_18; pfam12833
929556008433	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556008434	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
929556008435	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
929556008436	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556008437	Walker A/P-loop; other site
929556008438	ATP binding site [chemical binding]; other site
929556008439	Q-loop/lid; other site
929556008440	ABC transporter signature motif; other site
929556008441	Walker B; other site
929556008442	D-loop; other site
929556008443	H-loop/switch region; other site
929556008444	PAS fold; Region: PAS_3; pfam08447
929556008445	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
929556008446	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
929556008447	DNA binding residues [nucleotide binding]
929556008448	dimerization interface [polypeptide binding]; other site
929556008449	Domain of unknown function (DUF4136); Region: DUF4136; pfam13590
929556008450	enterobactin exporter EntS; Provisional; Region: PRK10489
929556008451	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556008452	putative substrate translocation pore; other site
929556008453	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
929556008454	PA_M28_2: Protease-associated (PA) domain, peptidase family M28, subfamily-2. A subfamily of PA-domain containing proteins belonging to the peptidase family M28. Family M28 contains aminopeptidases and carboxypeptidases, and has co-catalytic zinc ions; Region: PA_M28_2; cd04815
929556008455	PA/protease or protease-like domain interface [polypeptide binding]; other site
929556008456	M28 Zn-Peptidase Plasma glutamate carboxypeptidase; Region: M28_Pgcp_like; cd03883
929556008457	Peptidase family M28; Region: Peptidase_M28; pfam04389
929556008458	metal binding site [ion binding]; metal-binding site
929556008459	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
929556008460	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
929556008461	generic binding surface II; other site
929556008462	ssDNA binding site; other site
929556008463	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929556008464	ATP binding site [chemical binding]; other site
929556008465	putative Mg++ binding site [ion binding]; other site
929556008466	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929556008467	nucleotide binding region [chemical binding]; other site
929556008468	ATP-binding site [chemical binding]; other site
929556008469	Predicted permeases [General function prediction only]; Region: RarD; COG2962
929556008470	EamA-like transporter family; Region: EamA; pfam00892
929556008471	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
929556008472	homotrimer interaction site [polypeptide binding]; other site
929556008473	putative active site [active]
929556008474	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
929556008475	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
929556008476	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556008477	ligand binding site [chemical binding]; other site
929556008478	Aminopeptidase P, N-terminal domain; Region: AMP_N; smart01011
929556008479	proline aminopeptidase P II; Provisional; Region: PRK10879
929556008480	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
929556008481	active site
929556008482	LAO/AO transport system ATPase; Region: lao; TIGR00750
929556008483	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
929556008484	Walker A; other site
929556008485	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
929556008486	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
929556008487	putative metal binding site; other site
929556008488	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
929556008489	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
929556008490	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
929556008491	Walker A/P-loop; other site
929556008492	ATP binding site [chemical binding]; other site
929556008493	Q-loop/lid; other site
929556008494	ABC transporter signature motif; other site
929556008495	Walker B; other site
929556008496	D-loop; other site
929556008497	H-loop/switch region; other site
929556008498	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
929556008499	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
929556008500	active site
929556008501	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
929556008502	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
929556008503	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
929556008504	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
929556008505	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
929556008506	Probable Catalytic site; other site
929556008507	Glycosyl hydrolase family 99-like domain of WbsX-like glycosyltransferases; Region: Glyco_tran_WbsX; cd11579
929556008508	putative ligand binding site [chemical binding]; other site
929556008509	putative catalytic site [active]
929556008510	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
929556008511	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
929556008512	Family description; Region: VCBS; pfam13517
929556008513	Family description; Region: VCBS; pfam13517
929556008514	Family description; Region: VCBS; pfam13517
929556008515	Family description; Region: VCBS; pfam13517
929556008516	Family description; Region: VCBS; pfam13517
929556008517	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
929556008518	translation initiation factor IF-2; Region: IF-2; TIGR00487
929556008519	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
929556008520	G1 box; other site
929556008521	putative GEF interaction site [polypeptide binding]; other site
929556008522	GTP/Mg2+ binding site [chemical binding]; other site
929556008523	Switch I region; other site
929556008524	G2 box; other site
929556008525	G3 box; other site
929556008526	Switch II region; other site
929556008527	G4 box; other site
929556008528	G5 box; other site
929556008529	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
929556008530	Translation-initiation factor 2; Region: IF-2; pfam11987
929556008531	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
929556008532	transcription termination factor NusA; Region: NusA; TIGR01953
929556008533	NusA N-terminal domain; Region: NusA_N; pfam08529
929556008534	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
929556008535	RNA binding site [nucleotide binding]; other site
929556008536	homodimer interface [polypeptide binding]; other site
929556008537	NusA-like KH domain; Region: KH_5; pfam13184
929556008538	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
929556008539	G-X-X-G motif; other site
929556008540	ribosome maturation protein RimP; Reviewed; Region: PRK00092
929556008541	Sm and related proteins; Region: Sm_like; cl00259
929556008542	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
929556008543	putative oligomer interface [polypeptide binding]; other site
929556008544	putative RNA binding site [nucleotide binding]; other site
929556008545	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
929556008546	Peptidase family M1; Region: Peptidase_M1; pfam01433
929556008547	Zn binding site [ion binding]; other site
929556008548	HEAT repeats; Region: HEAT_2; pfam13646
929556008549	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
929556008550	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
929556008551	catalytic residues [active]
929556008552	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
929556008553	Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158
929556008554	FAD binding site [chemical binding]; other site
929556008555	homotetramer interface [polypeptide binding]; other site
929556008556	substrate binding pocket [chemical binding]; other site
929556008557	catalytic base [active]
929556008558	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
929556008559	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
929556008560	active site
929556008561	HIGH motif; other site
929556008562	nucleotide binding site [chemical binding]; other site
929556008563	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
929556008564	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
929556008565	tetramerization interface [polypeptide binding]; other site
929556008566	active site
929556008567	HYR domain; Region: HYR; pfam02494
929556008568	C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD); Region: AP_MHD_Cterm; cl10970
929556008569	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
929556008570	Calx-beta domain; Region: Calx-beta; cl02522
929556008571	legume lectins; Region: lectin_L-type; cl14058
929556008572	homotetramer interaction site [polypeptide binding]; other site
929556008573	carbohydrate binding site [chemical binding]; other site
929556008574	metal binding site [ion binding]; metal-binding site
929556008575	Parallel beta-helix repeat of pectate lyase; Region: PbH1; pfam13573
929556008576	pantoate--beta-alanine ligase; Region: panC; TIGR00018
929556008577	Pantoate-beta-alanine ligase; Region: PanC; cd00560
929556008578	active site
929556008579	ATP-binding site [chemical binding]; other site
929556008580	pantoate-binding site; other site
929556008581	HXXH motif; other site
929556008582	Starch synthase catalytic domain; Region: Glyco_transf_5; pfam08323
929556008583	Domain of unknown function (DUF4270); Region: DUF4270; pfam14092
929556008584	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
929556008585	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
929556008586	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
929556008587	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
929556008588	nucleoside/Zn binding site; other site
929556008589	dimer interface [polypeptide binding]; other site
929556008590	catalytic motif [active]
929556008591	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
929556008592	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
929556008593	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
929556008594	putative RNA binding site [nucleotide binding]; other site
929556008595	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556008596	S-adenosylmethionine binding site [chemical binding]; other site
929556008597	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
929556008598	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
929556008599	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
929556008600	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556008601	Uncharacterized conserved protein [Function unknown]; Region: COG2353
929556008602	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
929556008603	NADH(P)-binding; Region: NAD_binding_10; pfam13460
929556008604	NAD binding site [chemical binding]; other site
929556008605	substrate binding site [chemical binding]; other site
929556008606	putative active site [active]
929556008607	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
929556008608	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556008609	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556008610	DNA binding residues [nucleotide binding]
929556008611	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
929556008612	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
929556008613	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
929556008614	dimer interface [polypeptide binding]; other site
929556008615	anticodon binding site; other site
929556008616	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
929556008617	homodimer interface [polypeptide binding]; other site
929556008618	motif 1; other site
929556008619	active site
929556008620	motif 2; other site
929556008621	GAD domain; Region: GAD; pfam02938
929556008622	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
929556008623	motif 3; other site
929556008624	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
929556008625	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556008626	ligand binding site [chemical binding]; other site
929556008627	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
929556008628	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
929556008629	dimer interface [polypeptide binding]; other site
929556008630	ssDNA binding site [nucleotide binding]; other site
929556008631	tetramer (dimer of dimers) interface [polypeptide binding]; other site
929556008632	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
929556008633	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
929556008634	minor groove reading motif; other site
929556008635	helix-hairpin-helix signature motif; other site
929556008636	substrate binding pocket [chemical binding]; other site
929556008637	active site
929556008638	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
929556008639	DNA binding and oxoG recognition site [nucleotide binding]
929556008640	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
929556008641	IHF dimer interface [polypeptide binding]; other site
929556008642	IHF - DNA interface [nucleotide binding]; other site
929556008643	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556008644	TPR repeat; Region: TPR_11; pfam13414
929556008645	TPR motif; other site
929556008646	binding surface
929556008647	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556008648	Tetratricopeptide repeat; Region: TPR_1; pfam00515
929556008649	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
929556008650	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
929556008651	homodimer interface [polypeptide binding]; other site
929556008652	oligonucleotide binding site [chemical binding]; other site
929556008653	DNA repair protein RadA; Provisional; Region: PRK11823
929556008654	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
929556008655	Walker A motif/ATP binding site; other site
929556008656	ATP binding site [chemical binding]; other site
929556008657	Walker B motif; other site
929556008658	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
929556008659	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
929556008660	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
929556008661	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
929556008662	acyl-activating enzyme (AAE) consensus motif; other site
929556008663	acyl-activating enzyme (AAE) consensus motif; other site
929556008664	putative AMP binding site [chemical binding]; other site
929556008665	putative active site [active]
929556008666	putative CoA binding site [chemical binding]; other site
929556008667	2'-5' RNA ligase [Translation, ribosomal structure and biogenesis]; Region: LigT; COG1514
929556008668	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
929556008669	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
929556008670	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
929556008671	Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarB; COG0458
929556008672	ATP-grasp domain; Region: ATP-grasp_4; cl17255
929556008673	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
929556008674	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; smart01096
929556008675	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
929556008676	Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarB; COG0458
929556008677	ATP-grasp domain; Region: ATP-grasp_4; cl17255
929556008678	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
929556008679	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
929556008680	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
929556008681	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
929556008682	active site
929556008683	Zn binding site [ion binding]; other site
929556008684	AAA domain; Region: AAA_28; pfam13521
929556008685	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
929556008686	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556008687	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
929556008688	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556008689	DinB family; Region: DinB; cl17821
929556008690	DinB superfamily; Region: DinB_2; pfam12867
929556008691	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
929556008692	active site
929556008693	thiamine phosphate binding site [chemical binding]; other site
929556008694	pyrophosphate binding site [ion binding]; other site
929556008695	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
929556008696	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556008697	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
929556008698	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556008699	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
929556008700	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556008701	Coenzyme A binding pocket [chemical binding]; other site
929556008702	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
929556008703	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556008704	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556008705	DNA binding residues [nucleotide binding]
929556008706	YceI-like domain; Region: YceI; pfam04264
929556008707	CHRD domain; Region: CHRD; pfam07452
929556008708	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
929556008709	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
929556008710	Peptidase family M28; Region: Peptidase_M28; pfam04389
929556008711	metal binding site [ion binding]; metal-binding site
929556008712	Domain of unknown function (DUF4407); Region: DUF4407; pfam14362
929556008713	TPR repeat; Region: TPR_11; pfam13414
929556008714	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556008715	TPR motif; other site
929556008716	binding surface
929556008717	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
929556008718	argininosuccinate synthase; Provisional; Region: PRK13820
929556008719	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
929556008720	Ligand Binding Site [chemical binding]; other site
929556008721	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
929556008722	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
929556008723	Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992
929556008724	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
929556008725	inhibitor-cofactor binding pocket; inhibition site
929556008726	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556008727	catalytic residue [active]
929556008728	N-acetylornithine carbamoyltransferase; Reviewed; Region: PRK04523
929556008729	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
929556008730	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
929556008731	AAK_NAGK-like: N-Acetyl-L-glutamate kinase (NAGK)-like . Included in this CD are the Escherichia coli and Pseudomonas aeruginosa type NAGKs which catalyze the phosphorylation of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine...; Region: AAK_NAGK-like; cd04238
929556008732	nucleotide binding site [chemical binding]; other site
929556008733	N-acetyl-L-glutamate binding site [chemical binding]; other site
929556008734	pyrroline-5-carboxylate reductase; Region: proC; TIGR00112
929556008735	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
929556008736	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
929556008737	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like5; cd05651
929556008738	metal binding site [ion binding]; metal-binding site
929556008739	dimer interface [polypeptide binding]; other site
929556008740	hypothetical protein; Provisional; Region: PRK08317
929556008741	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556008742	S-adenosylmethionine binding site [chemical binding]; other site
929556008743	argininosuccinate lyase; Provisional; Region: PRK00855
929556008744	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
929556008745	active sites [active]
929556008746	tetramer interface [polypeptide binding]; other site
929556008747	Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975
929556008748	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
929556008749	M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299
929556008750	Zn binding site [ion binding]; other site
929556008751	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
929556008752	protein binding site [polypeptide binding]; other site
929556008753	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
929556008754	active site residue [active]
929556008755	8-oxoguanine DNA glycosylase, N-terminal domain; Region: OGG_N; pfam07934
929556008756	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
929556008757	endonuclease III; Region: ENDO3c; smart00478
929556008758	minor groove reading motif; other site
929556008759	helix-hairpin-helix signature motif; other site
929556008760	substrate binding pocket [chemical binding]; other site
929556008761	active site
929556008762	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_2; pfam13532
929556008763	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
929556008764	Uncharacterized protein conserved in bacteria (DUF2086); Region: DUF2086; pfam09859
929556008765	META domain; Region: META; pfam03724
929556008766	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
929556008767	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
929556008768	active site
929556008769	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
929556008770	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
929556008771	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
929556008772	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929556008773	NAD(P) binding site [chemical binding]; other site
929556008774	active site
929556008775	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
929556008776	inhibitor-cofactor binding pocket; inhibition site
929556008777	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556008778	catalytic residue [active]
929556008779	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
929556008780	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
929556008781	Ligand binding site; other site
929556008782	oligomer interface; other site
929556008783	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
929556008784	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
929556008785	active site
929556008786	NAD binding site [chemical binding]; other site
929556008787	metal binding site [ion binding]; metal-binding site
929556008788	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
929556008789	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
929556008790	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
929556008791	Ligand binding site; other site
929556008792	Putative Catalytic site; other site
929556008793	DXD motif; other site
929556008794	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
929556008795	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
929556008796	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
929556008797	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
929556008798	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
929556008799	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
929556008800	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
929556008801	putative hydrophobic ligand binding site [chemical binding]; other site
929556008802	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
929556008803	dimerization interface [polypeptide binding]; other site
929556008804	putative DNA binding site [nucleotide binding]; other site
929556008805	putative Zn2+ binding site [ion binding]; other site
929556008806	NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the...; Region: NTR_like; cl02512
929556008807	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
929556008808	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
929556008809	O-methyltransferase; Region: Methyltransf_2; pfam00891
929556008810	RibD C-terminal domain; Region: RibD_C; cl17279
929556008811	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
929556008812	Methylmalonyl-CoA epimerase (MMCE); Region: MMCE; cd07249
929556008813	substrate binding site [chemical binding]; other site
929556008814	metal binding site [ion binding]; metal-binding site
929556008815	dimer interface [polypeptide binding]; other site
929556008816	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556008817	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; cl01747
929556008818	RibD C-terminal domain; Region: RibD_C; cl17279
929556008819	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
929556008820	catalytic motif [active]
929556008821	Catalytic residue [active]
929556008822	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
929556008823	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
929556008824	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
929556008825	RibD C-terminal domain; Region: RibD_C; cl17279
929556008826	Domain of unknown function (DUF4348); Region: DUF4348; pfam14254
929556008827	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929556008828	salt bridge; other site
929556008829	non-specific DNA binding site [nucleotide binding]; other site
929556008830	sequence-specific DNA binding site [nucleotide binding]; other site
929556008831	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
929556008832	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
929556008833	dimer interface [polypeptide binding]; other site
929556008834	active site
929556008835	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929556008836	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929556008837	SnoaL-like domain; Region: SnoaL_2; pfam12680
929556008838	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
929556008839	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
929556008840	LytTr DNA-binding domain; Region: LytTR; smart00850
929556008841	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
929556008842	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
929556008843	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
929556008844	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
929556008845	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
929556008846	active site
929556008847	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
929556008848	putative DNA binding site [nucleotide binding]; other site
929556008849	dimerization interface [polypeptide binding]; other site
929556008850	putative Zn2+ binding site [ion binding]; other site
929556008851	Methyltransferase domain; Region: Methyltransf_31; pfam13847
929556008852	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556008853	S-adenosylmethionine binding site [chemical binding]; other site
929556008854	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
929556008855	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
929556008856	Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798
929556008857	arsenical-resistance protein; Region: acr3; TIGR00832
929556008858	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
929556008859	Low molecular weight phosphatase family; Region: LMWPc; cd00115
929556008860	active site
929556008861	di-heme enzyme, MXAN_0977 family; Region: MXAN_0977_Heme2; TIGR04039
929556008862	Predicted phosphatase [General function prediction only]; Region: PhoX; COG3211
929556008863	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
929556008864	Transcriptional regulator [Transcription]; Region: LysR; COG0583
929556008865	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
929556008866	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
929556008867	dimerization interface [polypeptide binding]; other site
929556008868	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
929556008869	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
929556008870	tetramer interface [polypeptide binding]; other site
929556008871	heme binding pocket [chemical binding]; other site
929556008872	NADPH binding site [chemical binding]; other site
929556008873	Peptidase M14-like domain; uncharacterized subgroup; Region: M14-like_1_4; cd06241
929556008874	putative active site [active]
929556008875	Zn binding site [ion binding]; other site
929556008876	PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH  (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme.  DCoH stimulates gene expression by...; Region: PCD_DCoH_subfamily_b; cd00914
929556008877	aromatic arch; other site
929556008878	DCoH dimer interaction site [polypeptide binding]; other site
929556008879	DCoH /HNF-1 dimer interaction site [polypeptide binding]; other site
929556008880	DCoH tetramer interaction site [polypeptide binding]; other site
929556008881	substrate binding site [chemical binding]; other site
929556008882	Protein of unknown function (DUF419); Region: DUF419; pfam04237
929556008883	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
929556008884	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929556008885	ATP binding site [chemical binding]; other site
929556008886	putative Mg++ binding site [ion binding]; other site
929556008887	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929556008888	nucleotide binding region [chemical binding]; other site
929556008889	ATP-binding site [chemical binding]; other site
929556008890	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556008891	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556008892	ligand binding site [chemical binding]; other site
929556008893	flexible hinge region; other site
929556008894	Pirin-related protein [General function prediction only]; Region: COG1741
929556008895	Pirin; Region: Pirin; pfam02678
929556008896	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
929556008897	Pirin-related protein [General function prediction only]; Region: COG1741
929556008898	Pirin; Region: Pirin; pfam02678
929556008899	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
929556008900	Predicted transcriptional regulator [Transcription]; Region: COG2378
929556008901	HTH domain; Region: HTH_11; pfam08279
929556008902	WYL domain; Region: WYL; pfam13280
929556008903	DinB family; Region: DinB; cl17821
929556008904	DinB superfamily; Region: DinB_2; pfam12867
929556008905	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
929556008906	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
929556008907	Protein of unknown function DUF72; Region: DUF72; pfam01904
929556008908	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
929556008909	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
929556008910	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556008911	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556008912	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556008913	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556008914	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556008915	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
929556008916	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556008917	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556008918	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556008919	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556008920	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556008921	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556008922	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5368
929556008923	Protein of unknown function (DUF3131); Region: DUF3131; pfam11329
929556008924	Putative glucoamylase; Region: Glycoamylase; pfam10091
929556008925	Glycosyl hydrolase family 43; Region: GH43_3; cd08982
929556008926	active site
929556008927	Coagulation factor 5/8 C-terminal domain, discoidin domain; Region: FA58C; smart00231
929556008928	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
929556008929	sugar binding site [chemical binding]; other site
929556008930	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
929556008931	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
929556008932	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
929556008933	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
929556008934	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
929556008935	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
929556008936	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556008937	RNA polymerase sigma-70 factor, TIGR02957 family; Region: SigX4
929556008938	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556008939	DNA binding residues [nucleotide binding]
929556008940	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
929556008941	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
929556008942	putative NAD(P) binding site [chemical binding]; other site
929556008943	putative substrate binding site [chemical binding]; other site
929556008944	catalytic Zn binding site [ion binding]; other site
929556008945	structural Zn binding site [ion binding]; other site
929556008946	dimer interface [polypeptide binding]; other site
929556008947	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
929556008948	putative hydrophobic ligand binding site [chemical binding]; other site
929556008949	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
929556008950	dimer interface [polypeptide binding]; other site
929556008951	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556008952	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
929556008953	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
929556008954	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977
929556008955	AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_2; cd03138
929556008956	conserved cys residue [active]
929556008957	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556008958	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231
929556008959	classical (c) SDRs; Region: SDR_c; cd05233
929556008960	NAD(P) binding site [chemical binding]; other site
929556008961	active site
929556008962	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
929556008963	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
929556008964	potential catalytic triad [active]
929556008965	conserved cys residue [active]
929556008966	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
929556008967	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
929556008968	FMN binding site [chemical binding]; other site
929556008969	active site
929556008970	substrate binding site [chemical binding]; other site
929556008971	catalytic residue [active]
929556008972	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
929556008973	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
929556008974	FMN binding site [chemical binding]; other site
929556008975	active site
929556008976	substrate binding site [chemical binding]; other site
929556008977	catalytic residue [active]
929556008978	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
929556008979	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
929556008980	active site
929556008981	catalytic tetrad [active]
929556008982	Transcriptional regulator [Transcription]; Region: LysR; COG0583
929556008983	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
929556008984	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
929556008985	dimerization interface [polypeptide binding]; other site
929556008986	Domain of unknown function (DUF1772); Region: DUF1772; pfam08592
929556008987	Methyltransferase domain; Region: Methyltransf_26; pfam13659
929556008988	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
929556008989	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
929556008990	active site
929556008991	HIGH motif; other site
929556008992	KMSKS motif; other site
929556008993	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
929556008994	tRNA binding surface [nucleotide binding]; other site
929556008995	anticodon binding site; other site
929556008996	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
929556008997	dimer interface [polypeptide binding]; other site
929556008998	putative tRNA-binding site [nucleotide binding]; other site
929556008999	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
929556009000	dimer interface [polypeptide binding]; other site
929556009001	catalytic triad [active]
929556009002	Lipid-binding putative hydrolase; Region: Lipid_bd; pfam12888
929556009003	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
929556009004	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
929556009005	starch binding outer membrane protein SusD; Region: SusD; cl17845
929556009006	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556009007	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556009008	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556009009	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556009010	Lipid-binding putative hydrolase; Region: Lipid_bd; pfam12888
929556009011	starch binding outer membrane protein SusD; Region: SusD; cl17845
929556009012	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556009013	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556009014	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556009015	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
929556009016	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556009017	Susd and RagB outer membrane lipoprotein; Region: SusD-like; pfam12741
929556009018	starch binding outer membrane protein SusD; Region: SusD; cl17845
929556009019	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556009020	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556009021	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556009022	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556009023	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
929556009024	starch binding outer membrane protein SusD; Region: SusD; cl17845
929556009025	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556009026	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556009027	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556009028	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556009029	Predicted transcriptional regulators [Transcription]; Region: COG1695
929556009030	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
929556009031	dimerization interface [polypeptide binding]; other site
929556009032	putative Zn2+ binding site [ion binding]; other site
929556009033	putative DNA binding site [nucleotide binding]; other site
929556009034	PspC domain; Region: PspC; pfam04024
929556009035	Peptidase M14-like domain; uncharacterized subgroup; Region: M14-like_1_1; cd06238
929556009036	putative active site [active]
929556009037	Zn binding site [ion binding]; other site
929556009038	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
929556009039	starch binding outer membrane protein SusD; Region: SusD; cd08977
929556009040	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
929556009041	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
929556009042	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556009043	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556009044	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556009045	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
929556009046	carboxyltransferase (CT) interaction site; other site
929556009047	biotinylation site [posttranslational modification]; other site
929556009048	Domain of unknown function (DUF4159); Region: DUF4159; pfam13709
929556009049	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
929556009050	RNA methyltransferase, RsmE family; Region: TIGR00046
929556009051	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
929556009052	Domain of unknown function DUF21; Region: DUF21; pfam01595
929556009053	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
929556009054	Transporter associated domain; Region: CorC_HlyC; smart01091
929556009055	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
929556009056	dimer interface [polypeptide binding]; other site
929556009057	substrate binding site [chemical binding]; other site
929556009058	metal binding sites [ion binding]; metal-binding site
929556009059	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
929556009060	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
929556009061	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
929556009062	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
929556009063	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
929556009064	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
929556009065	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
929556009066	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
929556009067	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
929556009068	NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus; Region: Oxidored_q1_C; pfam01010
929556009069	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
929556009070	NADH-ubiquinone/plastoquinone oxidoreductase chain 6; Region: Oxidored_q3; pfam00499
929556009071	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
929556009072	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
929556009073	4Fe-4S binding domain; Region: Fer4; cl02805
929556009074	4Fe-4S binding domain; Region: Fer4; pfam00037
929556009075	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
929556009076	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
929556009077	catalytic loop [active]
929556009078	iron binding site [ion binding]; other site
929556009079	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
929556009080	NADH-quinone oxidoreductase, F subunit; Region: nuoF_fam; TIGR01959
929556009081	SLBB domain; Region: SLBB; pfam10531
929556009082	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
929556009083	Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257
929556009084	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
929556009085	putative dimer interface [polypeptide binding]; other site
929556009086	[2Fe-2S] cluster binding site [ion binding]; other site
929556009087	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
929556009088	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
929556009089	NADH dehydrogenase subunit C; Provisional; Region: PRK06074
929556009090	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
929556009091	NADH dehydrogenase subunit B; Provisional; Region: PRK14820
929556009092	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
929556009093	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556009094	binding surface
929556009095	TPR motif; other site
929556009096	TPR repeat; Region: TPR_11; pfam13414
929556009097	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556009098	binding surface
929556009099	TPR motif; other site
929556009100	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556009101	binding surface
929556009102	TPR motif; other site
929556009103	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
929556009104	binding surface
929556009105	TPR motif; other site
929556009106	PBP superfamily domain; Region: PBP_like_2; pfam12849
929556009107	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
929556009108	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
929556009109	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
929556009110	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
929556009111	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
929556009112	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
929556009113	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
929556009114	active site
929556009115	substrate-binding site [chemical binding]; other site
929556009116	metal-binding site [ion binding]
929556009117	ATP binding site [chemical binding]; other site
929556009118	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
929556009119	putative rRNA binding site [nucleotide binding]; other site
929556009120	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
929556009121	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
929556009122	S-adenosylmethionine synthetase; Validated; Region: PRK05250
929556009123	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
929556009124	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
929556009125	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
929556009126	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
929556009127	ADP-ribose binding site [chemical binding]; other site
929556009128	dimer interface [polypeptide binding]; other site
929556009129	active site
929556009130	nudix motif; other site
929556009131	metal binding site [ion binding]; metal-binding site
929556009132	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
929556009133	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
929556009134	putative acyl-acceptor binding pocket; other site
929556009135	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
929556009136	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556009137	TPR motif; other site
929556009138	binding surface
929556009139	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
929556009140	Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236
929556009141	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
929556009142	Beta-Casp domain; Region: Beta-Casp; smart01027
929556009143	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
929556009144	M28 Zn-Peptidase Aeromonas (Vibrio) proteolytica aminopeptidase (AAP)-like; Region: M28_AAP_like; cd05642
929556009145	Peptidase family M28; Region: Peptidase_M28; pfam04389
929556009146	putative metal binding site [ion binding]; other site
929556009147	Predicted acyl esterases [General function prediction only]; Region: COG2936
929556009148	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556009149	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
929556009150	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
929556009151	succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Validated; Region: PRK07570
929556009152	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
929556009153	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK07573
929556009154	L-aspartate oxidase; Provisional; Region: PRK06175
929556009155	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
929556009156	succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; Region: sdhC_b558_fam; TIGR02046
929556009157	Succinate:quinone oxidoreductase (SQR)-like Type B subfamily 2, transmembrane subunit; composed of proteins with similarity to the SQRs of Geobacter metallireducens and Corynebacterium glutamicum. SQR catalyzes the oxidation of succinate to fumarate...; Region: SQR_TypeB_2_TM; cd03498
929556009158	putative Iron-sulfur protein interface [polypeptide binding]; other site
929556009159	proximal heme binding site [chemical binding]; other site
929556009160	distal heme binding site [chemical binding]; other site
929556009161	putative dimer interface [polypeptide binding]; other site
929556009162	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
929556009163	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
929556009164	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
929556009165	active site
929556009166	homodimer interface [polypeptide binding]; other site
929556009167	homotetramer interface [polypeptide binding]; other site
929556009168	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
929556009169	Aspartase; Region: Aspartase; cd01357
929556009170	active sites [active]
929556009171	tetramer interface [polypeptide binding]; other site
929556009172	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
929556009173	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
929556009174	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
929556009175	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
929556009176	protein binding site [polypeptide binding]; other site
929556009177	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
929556009178	protein binding site [polypeptide binding]; other site
929556009179	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
929556009180	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
929556009181	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
929556009182	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
929556009183	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556009184	active site
929556009185	phosphorylation site [posttranslational modification]
929556009186	intermolecular recognition site; other site
929556009187	dimerization interface [polypeptide binding]; other site
929556009188	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556009189	Walker A motif; other site
929556009190	ATP binding site [chemical binding]; other site
929556009191	Walker B motif; other site
929556009192	arginine finger; other site
929556009193	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
929556009194	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
929556009195	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
929556009196	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
929556009197	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
929556009198	Soluble P-type ATPase [General function prediction only]; Region: COG4087
929556009199	K+-transporting ATPase, c chain; Region: KdpC; cl00944
929556009200	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
929556009201	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
929556009202	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
929556009203	Ligand Binding Site [chemical binding]; other site
929556009204	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
929556009205	dimerization interface [polypeptide binding]; other site
929556009206	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
929556009207	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
929556009208	putative active site [active]
929556009209	heme pocket [chemical binding]; other site
929556009210	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556009211	dimer interface [polypeptide binding]; other site
929556009212	phosphorylation site [posttranslational modification]
929556009213	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556009214	ATP binding site [chemical binding]; other site
929556009215	Mg2+ binding site [ion binding]; other site
929556009216	G-X-G motif; other site
929556009217	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
929556009218	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
929556009219	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929556009220	NAD(P) binding site [chemical binding]; other site
929556009221	active site
929556009222	conserved hypothetical protein; Region: TIGR02231
929556009223	N-terminal domain of unknown function (DUF4140); Region: DUF4140; pfam13600
929556009224	Domain of unknown function (DUF4139); Region: DUF4139; pfam13598
929556009225	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
929556009226	Domain of unknown function (DUF4139); Region: DUF4139; pfam13598
929556009227	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
929556009228	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929556009229	ATP binding site [chemical binding]; other site
929556009230	putative Mg++ binding site [ion binding]; other site
929556009231	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929556009232	nucleotide binding region [chemical binding]; other site
929556009233	ATP-binding site [chemical binding]; other site
929556009234	hypothetical protein; Provisional; Region: PRK11770
929556009235	Domain of unknown function (DUF307); Region: DUF307; pfam03733
929556009236	Domain of unknown function (DUF307); Region: DUF307; pfam03733
929556009237	Membrane protein of unknown function; Region: DUF360; pfam04020
929556009238	Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system [Function unknown]; Region: COG4946
929556009239	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
929556009240	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
929556009241	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
929556009242	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
929556009243	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
929556009244	protein binding site [polypeptide binding]; other site
929556009245	Tricorn protease; serine protease family S41; Region: Peptidase_S41_TRI; cd07562
929556009246	Domain interface; other site
929556009247	Peptide binding site; other site
929556009248	Active site tetrad [active]
929556009249	putative bacillithiol system oxidoreductase, YpdA family; Region: Bthiol_YpdA; TIGR04018
929556009250	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
929556009251	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
929556009252	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4102
929556009253	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556009254	binding surface
929556009255	Tetratricopeptide repeat; Region: TPR_16; pfam13432
929556009256	TPR motif; other site
929556009257	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
929556009258	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
929556009259	RNA binding surface [nucleotide binding]; other site
929556009260	Protein of unknown function (DUF1365); Region: DUF1365; cl17838
929556009261	Flavin containing amine oxidoreductase; Region: Amino_oxidase; pfam01593
929556009262	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
929556009263	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_6; cd06154
929556009264	homotrimer interaction site [polypeptide binding]; other site
929556009265	putative active site [active]
929556009266	Fatty acid desaturase; Region: FA_desaturase; pfam00487
929556009267	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
929556009268	Di-iron ligands [ion binding]; other site
929556009269	The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505
929556009270	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
929556009271	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
929556009272	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
929556009273	active site
929556009274	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
929556009275	Ankyrin repeat; Region: Ank; pfam00023
929556009276	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
929556009277	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
929556009278	Ankyrin repeats (many copies); Region: Ank_4; pfam13637
929556009279	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
929556009280	Helix-turn-helix domain; Region: HTH_18; pfam12833
929556009281	Phosphoenolpyruvate:glucose-phosphotransferase regulator; Region: MtfA; cl01267
929556009282	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
929556009283	dimer interface [polypeptide binding]; other site
929556009284	substrate binding site [chemical binding]; other site
929556009285	ATP binding site [chemical binding]; other site
929556009286	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
929556009287	thiamine phosphate binding site [chemical binding]; other site
929556009288	active site
929556009289	pyrophosphate binding site [ion binding]; other site
929556009290	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
929556009291	substrate binding site [chemical binding]; other site
929556009292	multimerization interface [polypeptide binding]; other site
929556009293	ATP binding site [chemical binding]; other site
929556009294	hypothetical protein; Provisional; Region: PRK11239
929556009295	Protein of unknown function, DUF480; Region: DUF480; pfam04337
929556009296	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556009297	TPR motif; other site
929556009298	TPR repeat; Region: TPR_11; pfam13414
929556009299	binding surface
929556009300	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556009301	Coenzyme A binding pocket [chemical binding]; other site
929556009302	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
929556009303	cyclase homology domain; Region: CHD; cd07302
929556009304	nucleotidyl binding site; other site
929556009305	metal binding site [ion binding]; metal-binding site
929556009306	dimer interface [polypeptide binding]; other site
929556009307	Predicted integral membrane protein [Function unknown]; Region: COG5616
929556009308	TPR repeat; Region: TPR_11; pfam13414
929556009309	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556009310	TPR motif; other site
929556009311	binding surface
929556009312	TPR repeat; Region: TPR_11; pfam13414
929556009313	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556009314	TPR motif; other site
929556009315	binding surface
929556009316	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
929556009317	Uncharacterized conserved protein [Function unknown]; Region: COG2128
929556009318	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556009319	Cyclic nucleotide-binding domain; Region: cNMP_binding; pfam00027
929556009320	ligand binding site [chemical binding]; other site
929556009321	flexible hinge region; other site
929556009322	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
929556009323	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
929556009324	active site
929556009325	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
929556009326	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
929556009327	putative DNA binding site [nucleotide binding]; other site
929556009328	putative Zn2+ binding site [ion binding]; other site
929556009329	AsnC family; Region: AsnC_trans_reg; pfam01037
929556009330	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
929556009331	homotrimer interaction site [polypeptide binding]; other site
929556009332	putative active site [active]
929556009333	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
929556009334	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
929556009335	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929556009336	catalytic residue [active]
929556009337	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556009338	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
929556009339	Coenzyme A binding pocket [chemical binding]; other site
929556009340	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
929556009341	MPN+ (JAMM) motif; other site
929556009342	Zinc-binding site [ion binding]; other site
929556009343	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
929556009344	putative active site [active]
929556009345	Domain of unknown function (DUF4325); Region: DUF4325; pfam14213
929556009346	Mrr N-terminal domain; Region: Mrr_N; pfam14338
929556009347	Restriction endonuclease; Region: Mrr_cat; pfam04471
929556009348	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
929556009349	S1 domain; Region: S1_2; pfam13509
929556009350	S1 domain; Region: S1_2; pfam13509
929556009351	Bleomycin binding protein (BLMA) and similar proteins; BLMA confers bleomycin (Bm) resistance by directly binding to Bm; Region: BLMA_like; cd08349
929556009352	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556009353	ligand binding site [chemical binding]; other site
929556009354	dimer interface [polypeptide binding]; other site
929556009355	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
929556009356	active site clefts [active]
929556009357	zinc binding site [ion binding]; other site
929556009358	dimer interface [polypeptide binding]; other site
929556009359	Protein of unknown function (DUF4242); Region: DUF4242; pfam14026
929556009360	Protein of unknown function (DUF4242); Region: DUF4242; pfam14026
929556009361	Protein of unknown function (DUF4242); Region: DUF4242; pfam14026
929556009362	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
929556009363	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
929556009364	metal binding site [ion binding]; metal-binding site
929556009365	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556009366	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556009367	MAC/Perforin domain; Region: MACPF; cl02616
929556009368	Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cl02488
929556009369	linker region; other site
929556009370	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
929556009371	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
929556009372	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
929556009373	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
929556009374	dimer interface [polypeptide binding]; other site
929556009375	FMN binding site [chemical binding]; other site
929556009376	Pirin-related protein [General function prediction only]; Region: COG1741
929556009377	Pirin; Region: Pirin; pfam02678
929556009378	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
929556009379	NADH(P)-binding; Region: NAD_binding_10; pfam13460
929556009380	NAD binding site [chemical binding]; other site
929556009381	active site
929556009382	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
929556009383	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
929556009384	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
929556009385	Bacterial Ig-like domain; Region: Big_5; pfam13205
929556009386	Scramblase; Region: Scramblase; pfam03803
929556009387	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
929556009388	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
929556009389	trimer interface [polypeptide binding]; other site
929556009390	putative metal binding site [ion binding]; other site
929556009391	L-aspartate oxidase; Provisional; Region: PRK09077
929556009392	L-aspartate oxidase; Provisional; Region: PRK06175
929556009393	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
929556009394	quinolinate synthetase; Provisional; Region: PRK09375
929556009395	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
929556009396	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929556009397	Zn2+ binding site [ion binding]; other site
929556009398	Mg2+ binding site [ion binding]; other site
929556009399	Lin1944 and related proteins, classical (c) SDRs; Region: Lin1944_like_SDR_c; cd11731
929556009400	3-ketoacyl-(acyl-carrier-protein) reductase; Reviewed; Region: PRK12826
929556009401	putative NAD(P) binding site [chemical binding]; other site
929556009402	homodimer interface [polypeptide binding]; other site
929556009403	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
929556009404	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
929556009405	DUP family; Region: DUP; pfam00674
929556009406	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3786
929556009407	thiamine monophosphate kinase; Provisional; Region: PRK05731
929556009408	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
929556009409	ATP binding site [chemical binding]; other site
929556009410	dimerization interface [polypeptide binding]; other site
929556009411	Protein of unknown function, DUF481; Region: DUF481; cl01213
929556009412	Cupin superfamily (DUF985); Region: Cupin_5; pfam06172
929556009413	DinB family; Region: DinB; cl17821
929556009414	DinB superfamily; Region: DinB_2; pfam12867
929556009415	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556009416	S-adenosylmethionine binding site [chemical binding]; other site
929556009417	Predicted nucleotidyltransferase; Region: Nuc-transf; cl01417
929556009418	Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127
929556009419	Predicted membrane protein [Function unknown]; Region: COG4682
929556009420	yiaA/B two helix domain; Region: YiaAB; pfam05360
929556009421	yiaA/B two helix domain; Region: YiaAB; pfam05360
929556009422	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
929556009423	active site
929556009424	thiamine phosphate binding site [chemical binding]; other site
929556009425	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
929556009426	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
929556009427	ATP binding site [chemical binding]; other site
929556009428	substrate interface [chemical binding]; other site
929556009429	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
929556009430	active site residue [active]
929556009431	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
929556009432	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929556009433	FeS/SAM binding site; other site
929556009434	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
929556009435	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
929556009436	ThiS interaction site; other site
929556009437	putative active site [active]
929556009438	tetramer interface [polypeptide binding]; other site
929556009439	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
929556009440	active site
929556009441	thiamine phosphate binding site [chemical binding]; other site
929556009442	pyrophosphate binding site [ion binding]; other site
929556009443	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
929556009444	ThiC-associated domain; Region: ThiC-associated; pfam13667
929556009445	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
929556009446	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
929556009447	thiS-thiF/thiG interaction site; other site
929556009448	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
929556009449	hypothetical protein; Reviewed; Region: PRK09588
929556009450	TROVE domain; Region: TROVE; pfam05731
929556009451	Uncharacterized protein family UPF0547; Region: UPF0547; pfam10571
929556009452	Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_8; cd08901
929556009453	putative hydrophobic ligand binding site [chemical binding]; other site
929556009454	WYL domain; Region: WYL; pfam13280
929556009455	FAD binding domain; Region: FAD_binding_4; pfam01565
929556009456	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
929556009457	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
929556009458	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
929556009459	PAS fold; Region: PAS_3; pfam08447
929556009460	putative active site [active]
929556009461	heme pocket [chemical binding]; other site
929556009462	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
929556009463	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
929556009464	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556009465	Walker A/P-loop; other site
929556009466	ATP binding site [chemical binding]; other site
929556009467	Q-loop/lid; other site
929556009468	ABC transporter signature motif; other site
929556009469	Walker B; other site
929556009470	D-loop; other site
929556009471	H-loop/switch region; other site
929556009472	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
929556009473	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
929556009474	dimer interface [polypeptide binding]; other site
929556009475	putative radical transfer pathway; other site
929556009476	diiron center [ion binding]; other site
929556009477	tyrosyl radical; other site
929556009478	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09102
929556009479	Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317
929556009480	Class I ribonucleotide reductase; Region: RNR_I; cd01679
929556009481	active site
929556009482	dimer interface [polypeptide binding]; other site
929556009483	catalytic residues [active]
929556009484	effector binding site; other site
929556009485	R2 peptide binding site; other site
929556009486	RmuC family; Region: RmuC; pfam02646
929556009487	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
929556009488	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
929556009489	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
929556009490	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
929556009491	FMN binding site [chemical binding]; other site
929556009492	active site
929556009493	catalytic residues [active]
929556009494	substrate binding site [chemical binding]; other site
929556009495	CAAX protease self-immunity; Region: Abi; pfam02517
929556009496	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
929556009497	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
929556009498	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
929556009499	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
929556009500	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
929556009501	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
929556009502	NAD(P) binding site [chemical binding]; other site
929556009503	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
929556009504	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
929556009505	Mechanosensitive ion channel; Region: MS_channel; pfam00924
929556009506	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
929556009507	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
929556009508	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
929556009509	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
929556009510	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
929556009511	ligand binding site [chemical binding]; other site
929556009512	flexible hinge region; other site
929556009513	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
929556009514	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556009515	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
929556009516	RimM N-terminal domain; Region: RimM; pfam01782
929556009517	30S ribosomal protein S16; Provisional; Region: rpsP; PRK14521
929556009518	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
929556009519	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C); Region: NT5C; cl17836
929556009520	Protein of unknown function (DUF458); Region: DUF458; cl00861
929556009521	Domain of unknown function (DUF4198); Region: DUF4198; pfam10670
929556009522	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
929556009523	heat shock protein 90; Provisional; Region: PRK05218
929556009524	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556009525	ATP binding site [chemical binding]; other site
929556009526	Mg2+ binding site [ion binding]; other site
929556009527	G-X-G motif; other site
929556009528	D-glucuronyl C5-epimerase C-terminus; Region: C5-epim_C; pfam06662
929556009529	Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070
929556009530	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
929556009531	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929556009532	FeS/SAM binding site; other site
929556009533	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
929556009534	classical (c) SDRs; Region: SDR_c; cd05233
929556009535	NAD(P) binding site [chemical binding]; other site
929556009536	active site
929556009537	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
929556009538	B12 binding site [chemical binding]; other site
929556009539	cobalt ligand [ion binding]; other site
929556009540	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
929556009541	Walker A; other site
929556009542	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM)-like family; contains proteins similar to MCM, and the large subunit of Streptomyces coenzyme B12-dependent isobutyryl-CoA mutase (ICM). MCM catalyzes the isomerization of...; Region: MM_CoA_mutase; cl00817
929556009543	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM)-like family; contains proteins similar to MCM, and the large subunit of Streptomyces coenzyme B12-dependent isobutyryl-CoA mutase (ICM). MCM catalyzes the isomerization of...; Region: MM_CoA_mutase; cl00817
929556009544	leukotriene A-4 hydrolase/aminopeptidase; Region: leuko_A4_hydro; TIGR02411
929556009545	Peptidase M1 family contains leukotriene A4 hydrolase; Region: M1_LTA4H; cd09599
929556009546	active site
929556009547	Zn binding site [ion binding]; other site
929556009548	Leukotriene A4 hydrolase, C-terminal; Region: Leuk-A4-hydro_C; pfam09127
929556009549	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556009550	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
929556009551	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
929556009552	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556009553	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556009554	DNA binding residues [nucleotide binding]
929556009555	Domain of unknown function (DUF4136); Region: DUF4136; pfam13590
929556009556	signal recognition particle protein; Provisional; Region: PRK10867
929556009557	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
929556009558	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
929556009559	P loop; other site
929556009560	GTP binding site [chemical binding]; other site
929556009561	Signal peptide binding domain; Region: SRP_SPB; pfam02978
929556009562	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
929556009563	Zn binding site [ion binding]; other site
929556009564	carboxy-terminal protease; Provisional; Region: PRK11186
929556009565	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
929556009566	protein binding site [polypeptide binding]; other site
929556009567	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
929556009568	Catalytic dyad [active]
929556009569	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
929556009570	Methyltransferase domain; Region: Methyltransf_23; pfam13489
929556009571	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556009572	S-adenosylmethionine binding site [chemical binding]; other site
929556009573	YceI-like domain; Region: YceI; pfam04264
929556009574	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929556009575	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556009576	active site
929556009577	phosphorylation site [posttranslational modification]
929556009578	intermolecular recognition site; other site
929556009579	dimerization interface [polypeptide binding]; other site
929556009580	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929556009581	DNA binding site [nucleotide binding]
929556009582	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556009583	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556009584	dimer interface [polypeptide binding]; other site
929556009585	phosphorylation site [posttranslational modification]
929556009586	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556009587	ATP binding site [chemical binding]; other site
929556009588	Mg2+ binding site [ion binding]; other site
929556009589	G-X-G motif; other site
929556009590	Monoamine oxidase [Amino acid transport and metabolism]; Region: COG1231
929556009591	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
929556009592	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556009593	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556009594	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
929556009595	substrate binding site [chemical binding]; other site
929556009596	Domain of unknown function (DUF3127); Region: DUF3127; pfam11325
929556009597	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
929556009598	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
929556009599	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556009600	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
929556009601	homodimer interaction site [polypeptide binding]; other site
929556009602	cofactor binding site; other site
929556009603	Uncharacterized conserved protein (DUF2196); Region: DUF2196; pfam09962
929556009604	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556009605	von Willebrand factor; Region: vWF_A; pfam12450
929556009606	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
929556009607	VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subgroup; cd01465
929556009608	metal ion-dependent adhesion site (MIDAS); other site
929556009609	Domain of unknown function (DUF3520); Region: DUF3520; pfam12034
929556009610	Transposase IS200 like; Region: Y1_Tnp; cl00848
929556009611	Protein of unknown function (DUF3478); Region: DUF3478; pfam11964
929556009612	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
929556009613	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
929556009614	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
929556009615	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556009616	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556009617	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556009618	dimer interface [polypeptide binding]; other site
929556009619	phosphorylation site [posttranslational modification]
929556009620	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556009621	ATP binding site [chemical binding]; other site
929556009622	Mg2+ binding site [ion binding]; other site
929556009623	G-X-G motif; other site
929556009624	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929556009625	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556009626	active site
929556009627	phosphorylation site [posttranslational modification]
929556009628	intermolecular recognition site; other site
929556009629	dimerization interface [polypeptide binding]; other site
929556009630	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929556009631	DNA binding site [nucleotide binding]
929556009632	Uncharacterized protein related to plant photosystem II stability/assembly factor [General function prediction only]; Region: COG4447
929556009633	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
929556009634	Protein of unknown function (DUF3820); Region: DUF3820; pfam12843
929556009635	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
929556009636	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
929556009637	Fn3 associated; Region: Fn3_assoc; pfam13287
929556009638	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
929556009639	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
929556009640	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
929556009641	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
929556009642	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
929556009643	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_3; cd09620
929556009644	putative ligand binding site [chemical binding]; other site
929556009645	Sulfatase; Region: Sulfatase; pfam00884
929556009646	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
929556009647	DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024
929556009648	catalytic residues [active]
929556009649	Protein of unknown function (Porph_ging); Region: Porph_ging; cl09903
929556009650	Domain of unknown function (DUF4412); Region: DUF4412; pfam14371
929556009651	Putative carbohydrate binding domain; Region: CHB_HEX; cl03918
929556009652	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
929556009653	Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948
929556009654	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
929556009655	active site
929556009656	C-terminal Early set domain associated with the catalytic domain of chitobiase (also called N-acetylglucosaminidase); Region: E_set_Chitobiase_C; cd02847
929556009657	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
929556009658	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
929556009659	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
929556009660	active site
929556009661	metal binding site [ion binding]; metal-binding site
929556009662	homotetramer interface [polypeptide binding]; other site
929556009663	polyphosphate:nucleotide phosphotransferase, PPK2 family; Region: PPK2_rel_1; TIGR03709
929556009664	Uncharacterized ACR, COG1430; Region: DUF192; pfam02643
929556009665	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
929556009666	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
929556009667	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
929556009668	dimerization interface [polypeptide binding]; other site
929556009669	DPS ferroxidase diiron center [ion binding]; other site
929556009670	ion pore; other site
929556009671	C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some...; Region: Peptidase_C1; cd02619
929556009672	active site
929556009673	metal-dependent hydrolase; Provisional; Region: PRK13291
929556009674	DinB superfamily; Region: DinB_2; pfam12867
929556009675	Protein of unknown function, DUF606; Region: DUF606; pfam04657
929556009676	Bacterial protein of unknown function (DUF885); Region: DUF885; pfam05960
929556009677	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
929556009678	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
929556009679	amidase catalytic site [active]
929556009680	Zn binding residues [ion binding]; other site
929556009681	substrate binding site [chemical binding]; other site
929556009682	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
929556009683	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
929556009684	active site
929556009685	Zn binding site [ion binding]; other site
929556009686	Domain of unknown function (DUF4180); Region: DUF4180; pfam13788
929556009687	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
929556009688	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
929556009689	HIGH motif; other site
929556009690	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
929556009691	active site
929556009692	KMSKS motif; other site
929556009693	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556009694	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556009695	phosphorylation site [posttranslational modification]
929556009696	dimer interface [polypeptide binding]; other site
929556009697	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556009698	ATP binding site [chemical binding]; other site
929556009699	Mg2+ binding site [ion binding]; other site
929556009700	G-X-G motif; other site
929556009701	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
929556009702	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
929556009703	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
929556009704	hexamer interface [polypeptide binding]; other site
929556009705	ligand binding site [chemical binding]; other site
929556009706	putative active site [active]
929556009707	NAD(P) binding site [chemical binding]; other site
929556009708	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
929556009709	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
929556009710	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
929556009711	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929556009712	catalytic residue [active]
929556009713	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
929556009714	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
929556009715	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556009716	Walker A motif; other site
929556009717	ATP binding site [chemical binding]; other site
929556009718	Walker B motif; other site
929556009719	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
929556009720	Prostaglandin dehydrogenases; Region: PGDH; cd05288
929556009721	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
929556009722	NAD(P) binding site [chemical binding]; other site
929556009723	substrate binding site [chemical binding]; other site
929556009724	dimer interface [polypeptide binding]; other site
929556009725	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
929556009726	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
929556009727	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
929556009728	potential catalytic triad [active]
929556009729	conserved cys residue [active]
929556009730	Transcriptional regulators [Transcription]; Region: MarR; COG1846
929556009731	MarR family; Region: MarR; pfam01047
929556009732	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
929556009733	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
929556009734	putative NAD(P) binding site [chemical binding]; other site
929556009735	putative substrate binding site [chemical binding]; other site
929556009736	catalytic Zn binding site [ion binding]; other site
929556009737	structural Zn binding site [ion binding]; other site
929556009738	dimer interface [polypeptide binding]; other site
929556009739	Uncharacterized conserved protein [Function unknown]; Region: COG1262
929556009740	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
929556009741	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
929556009742	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
929556009743	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556009744	aspartate-alanine antiporter; Region: Asp_Ala_antiprt; TIGR03802
929556009745	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
929556009746	TrkA-C domain; Region: TrkA_C; pfam02080
929556009747	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
929556009748	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
929556009749	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556009750	Coenzyme A binding pocket [chemical binding]; other site
929556009751	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
929556009752	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
929556009753	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
929556009754	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
929556009755	DNA primase; Validated; Region: dnaG; PRK05667
929556009756	CHC2 zinc finger; Region: zf-CHC2; pfam01807
929556009757	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
929556009758	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
929556009759	active site
929556009760	metal binding site [ion binding]; metal-binding site
929556009761	interdomain interaction site; other site
929556009762	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
929556009763	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
929556009764	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
929556009765	trimer interface [polypeptide binding]; other site
929556009766	active site
929556009767	MG2 domain; Region: A2M_N; pfam01835
929556009768	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
929556009769	Serine proteases of the peptidase family S9A [Amino acid transport and metabolism]; Region: COG1505
929556009770	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556009771	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
929556009772	putative active site [active]
929556009773	putative metal binding site [ion binding]; other site
929556009774	peptide chain release factor 1; Validated; Region: prfA; PRK00591
929556009775	This domain is found in peptide chain release factors; Region: PCRF; smart00937
929556009776	RF-1 domain; Region: RF-1; pfam00472
929556009777	Catalytic GIY-YIG domain of yeast structure-specific endonuclease subunit SLX1 and its homologs; Region: GIY-YIG_SLX1_like; cd10449
929556009778	GIY-YIG motif/motif A; other site
929556009779	putative active site [active]
929556009780	putative metal binding site [ion binding]; other site
929556009781	Histidine kinase; Region: HisKA_3; pfam07730
929556009782	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
929556009783	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
929556009784	E-class dimer interface [polypeptide binding]; other site
929556009785	P-class dimer interface [polypeptide binding]; other site
929556009786	active site
929556009787	Cu2+ binding site [ion binding]; other site
929556009788	Zn2+ binding site [ion binding]; other site
929556009789	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556009790	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
929556009791	Histidine kinase; Region: HisKA_3; pfam07730
929556009792	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556009793	ATP binding site [chemical binding]; other site
929556009794	Mg2+ binding site [ion binding]; other site
929556009795	G-X-G motif; other site
929556009796	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
929556009797	metal binding site [ion binding]; metal-binding site
929556009798	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
929556009799	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
929556009800	FAD binding pocket [chemical binding]; other site
929556009801	conserved FAD binding motif [chemical binding]; other site
929556009802	phosphate binding motif [ion binding]; other site
929556009803	beta-alpha-beta structure motif; other site
929556009804	NAD binding pocket [chemical binding]; other site
929556009805	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
929556009806	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556009807	TPR repeat; Region: TPR_11; pfam13414
929556009808	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556009809	TPR motif; other site
929556009810	binding surface
929556009811	TPR repeat; Region: TPR_11; pfam13414
929556009812	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556009813	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
929556009814	dimer interface [polypeptide binding]; other site
929556009815	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
929556009816	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556009817	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556009818	DNA binding residues [nucleotide binding]
929556009819	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
929556009820	OsmC-like protein; Region: OsmC; cl00767
929556009821	Protein of unknown function (DUF1271); Region: DUF1271; pfam06902
929556009822	Predicted flavoprotein [General function prediction only]; Region: COG0431
929556009823	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
929556009824	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
929556009825	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
929556009826	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
929556009827	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
929556009828	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
929556009829	putative active site [active]
929556009830	putative metal binding site [ion binding]; other site
929556009831	uncharacterized subgroup of aldehyde reductase and flavonoid reductase related proteins, extended (e) SDRs; Region: AR_FR_like_1_SDR_e; cd05228
929556009832	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
929556009833	putative NADP binding site [chemical binding]; other site
929556009834	putative substrate binding site [chemical binding]; other site
929556009835	active site
929556009836	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
929556009837	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
929556009838	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
929556009839	L-serine binding site [chemical binding]; other site
929556009840	ACT domain interface; other site
929556009841	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
929556009842	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
929556009843	agmatinase; Region: agmatinase; TIGR01230
929556009844	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
929556009845	putative active site [active]
929556009846	putative metal binding site [ion binding]; other site
929556009847	imidazolonepropionase; Validated; Region: PRK09356
929556009848	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
929556009849	active site
929556009850	Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281
929556009851	putative active site [active]
929556009852	putative catalytic site [active]
929556009853	putative DNA binding site [nucleotide binding]; other site
929556009854	putative phosphate binding site [ion binding]; other site
929556009855	metal binding site A [ion binding]; metal-binding site
929556009856	putative AP binding site [nucleotide binding]; other site
929556009857	putative metal binding site B [ion binding]; other site
929556009858	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
929556009859	active site
929556009860	Low affinity iron permease; Region: Iron_permease; pfam04120
929556009861	Protein of unknown function (DUF4242); Region: DUF4242; pfam14026
929556009862	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
929556009863	urocanate hydratase; Provisional; Region: PRK05414
929556009864	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556009865	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
929556009866	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
929556009867	N-terminal plug; other site
929556009868	ligand-binding site [chemical binding]; other site
929556009869	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
929556009870	catalytic motif [active]
929556009871	Catalytic residue [active]
929556009872	Aspartyl protease; Region: Asp_protease_2; pfam13650
929556009873	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
929556009874	protein binding site [polypeptide binding]; other site
929556009875	Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_2; cd04276
929556009876	active site
929556009877	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
929556009878	glucosamine-6-phosphate deaminase-like protein; Validated; Region: PRK02122
929556009879	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
929556009880	active site
929556009881	trimer interface [polypeptide binding]; other site
929556009882	allosteric site; other site
929556009883	active site lid [active]
929556009884	hexamer (dimer of trimers) interface [polypeptide binding]; other site
929556009885	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
929556009886	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
929556009887	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556009888	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
929556009889	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
929556009890	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
929556009891	Interdomain contacts; other site
929556009892	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
929556009893	basic leucine zipper DNA-binding and multimerization region of GCN4 and related proteins; Region: B_zip1; cl02576
929556009894	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556009895	HAMP domain; Region: HAMP; pfam00672
929556009896	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556009897	dimer interface [polypeptide binding]; other site
929556009898	phosphorylation site [posttranslational modification]
929556009899	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556009900	ATP binding site [chemical binding]; other site
929556009901	Mg2+ binding site [ion binding]; other site
929556009902	G-X-G motif; other site
929556009903	Transposase, Mutator family; Region: Transposase_mut; pfam00872
929556009904	MULE transposase domain; Region: MULE; pfam10551
929556009905	Preprotein translocase SecG subunit; Region: SecG; pfam03840
929556009906	Lipopolysaccharide-assembly; Region: LptE; cl01125
929556009907	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556009908	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
929556009909	Walker A motif; other site
929556009910	ATP binding site [chemical binding]; other site
929556009911	Walker B motif; other site
929556009912	arginine finger; other site
929556009913	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14329
929556009914	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
929556009915	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929556009916	FeS/SAM binding site; other site
929556009917	TRAM domain; Region: TRAM; pfam01938
929556009918	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
929556009919	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
929556009920	homodimer interface [polypeptide binding]; other site
929556009921	substrate-cofactor binding pocket; other site
929556009922	catalytic residue [active]
929556009923	Tryptophan 2,3-dioxygenase; Region: Trp_dioxygenase; cl03994
929556009924	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
929556009925	ClC sycA-like chloride channel proteins. This ClC family presents in bacteria, where it facilitates acid resistance in acidic soil. Mutation of this gene (sycA) in Rhizobium tropici CIAT899 causes serious deficiencies in nodule development, nodulation...; Region: ClC_sycA_like; cd03682
929556009926	putative Cl- selectivity filter; other site
929556009927	putative pore gating glutamate residue; other site
929556009928	elongation factor P; Validated; Region: PRK00529
929556009929	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
929556009930	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
929556009931	RNA binding site [nucleotide binding]; other site
929556009932	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
929556009933	RNA binding site [nucleotide binding]; other site
929556009934	Predicted transcriptional regulator [Transcription]; Region: COG2378
929556009935	HTH domain; Region: HTH_11; pfam08279
929556009936	WYL domain; Region: WYL; pfam13280
929556009937	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
929556009938	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
929556009939	active site
929556009940	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4430
929556009941	DinB family; Region: DinB; cl17821
929556009942	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
929556009943	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
929556009944	Walker A/P-loop; other site
929556009945	ATP binding site [chemical binding]; other site
929556009946	Q-loop/lid; other site
929556009947	ABC transporter signature motif; other site
929556009948	Walker B; other site
929556009949	D-loop; other site
929556009950	H-loop/switch region; other site
929556009951	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
929556009952	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
929556009953	active site
929556009954	bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Reviewed; Region: PRK13188
929556009955	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
929556009956	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
929556009957	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
929556009958	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
929556009959	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
929556009960	trimer interface [polypeptide binding]; other site
929556009961	active site
929556009962	UDP-GlcNAc binding site [chemical binding]; other site
929556009963	lipid binding site [chemical binding]; lipid-binding site
929556009964	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
929556009965	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
929556009966	Zn2+ binding site [ion binding]; other site
929556009967	Mg2+ binding site [ion binding]; other site
929556009968	Response regulator receiver domain; Region: Response_reg; pfam00072
929556009969	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556009970	active site
929556009971	phosphorylation site [posttranslational modification]
929556009972	intermolecular recognition site; other site
929556009973	dimerization interface [polypeptide binding]; other site
929556009974	PglZ domain; Region: PglZ; pfam08665
929556009975	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
929556009976	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
929556009977	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
929556009978	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
929556009979	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
929556009980	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
929556009981	metal-binding site
929556009982	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
929556009983	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
929556009984	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
929556009985	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
929556009986	trimer interface [polypeptide binding]; other site
929556009987	active site
929556009988	substrate binding site [chemical binding]; other site
929556009989	CoA binding site [chemical binding]; other site
929556009990	Protein of unknown function (DUF2911); Region: DUF2911; pfam11138
929556009991	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
929556009992	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
929556009993	metal binding site [ion binding]; metal-binding site
929556009994	dimer interface [polypeptide binding]; other site
929556009995	Sporulation related domain; Region: SPOR; pfam05036
929556009996	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12901
929556009997	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
929556009998	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929556009999	nucleotide binding region [chemical binding]; other site
929556010000	ATP-binding site [chemical binding]; other site
929556010001	SEC-C motif; Region: SEC-C; pfam02810
929556010002	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
929556010003	putative catalytic site [active]
929556010004	putative metal binding site [ion binding]; other site
929556010005	putative phosphate binding site [ion binding]; other site
929556010006	DNA polymerase I; Region: pola; TIGR00593
929556010007	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
929556010008	active site
929556010009	metal binding site 1 [ion binding]; metal-binding site
929556010010	putative 5' ssDNA interaction site; other site
929556010011	metal binding site 3; metal-binding site
929556010012	metal binding site 2 [ion binding]; metal-binding site
929556010013	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
929556010014	putative DNA binding site [nucleotide binding]; other site
929556010015	putative metal binding site [ion binding]; other site
929556010016	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
929556010017	active site
929556010018	catalytic site [active]
929556010019	substrate binding site [chemical binding]; other site
929556010020	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
929556010021	active site
929556010022	DNA binding site [nucleotide binding]
929556010023	catalytic site [active]
929556010024	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
929556010025	active sites [active]
929556010026	tetramer interface [polypeptide binding]; other site
929556010027	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
929556010028	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
929556010029	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
929556010030	dimer interface [polypeptide binding]; other site
929556010031	active site
929556010032	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
929556010033	6-phosphofructokinase; Provisional; Region: PRK03202
929556010034	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
929556010035	active site
929556010036	ADP/pyrophosphate binding site [chemical binding]; other site
929556010037	dimerization interface [polypeptide binding]; other site
929556010038	allosteric effector site; other site
929556010039	fructose-1,6-bisphosphate binding site; other site
929556010040	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
929556010041	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
929556010042	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
929556010043	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
929556010044	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
929556010045	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
929556010046	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
929556010047	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
929556010048	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556010049	Walker A motif; other site
929556010050	ATP binding site [chemical binding]; other site
929556010051	Walker B motif; other site
929556010052	arginine finger; other site
929556010053	Peptidase family M41; Region: Peptidase_M41; pfam01434
929556010054	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
929556010055	hypothetical protein; Reviewed; Region: PRK12497
929556010056	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
929556010057	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_like_1; cd01832
929556010058	active site
929556010059	catalytic triad [active]
929556010060	oxyanion hole [active]
929556010061	Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975
929556010062	M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299
929556010063	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
929556010064	nudix motif; other site
929556010065	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
929556010066	bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase; Provisional; Region: PRK05379
929556010067	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
929556010068	active site
929556010069	nucleotide binding site [chemical binding]; other site
929556010070	HIGH motif; other site
929556010071	KMSKS motif; other site
929556010072	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
929556010073	nudix motif; other site
929556010074	putative nicotinate phosphoribosyltransferase; Provisional; Region: PRK09198
929556010075	pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of nicotinate phosphoribosyltransferases (NAPRTases) were originally identified as genes whose expression is upregulated upon activation in lymphoid cells. In general; Region: PBEF_like; cd01569
929556010076	active site
929556010077	Peptidase family M54, also called archaemetzincins or archaelysins; Region: Peptidase_M54; cd11375
929556010078	active site
929556010079	Zn binding site [ion binding]; other site
929556010080	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
929556010081	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
929556010082	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556010083	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
929556010084	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556010085	Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814
929556010086	putative hydrophobic ligand binding site [chemical binding]; other site
929556010087	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
929556010088	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
929556010089	ring oligomerisation interface [polypeptide binding]; other site
929556010090	ATP/Mg binding site [chemical binding]; other site
929556010091	stacking interactions; other site
929556010092	hinge regions; other site
929556010093	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
929556010094	oligomerisation interface [polypeptide binding]; other site
929556010095	mobile loop; other site
929556010096	roof hairpin; other site
929556010097	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556010098	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
929556010099	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556010100	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
929556010101	MG2 domain; Region: A2M_N; pfam01835
929556010102	GldH lipoprotein; Region: GldH_lipo; pfam14109
929556010103	PSP1 C-terminal conserved region; Region: PSP1; cl00770
929556010104	DNA polymerase III, delta subunit; Region: DNA_pol3_delta2; pfam13177
929556010105	DNA polymerase III subunit delta'; Validated; Region: PRK08485
929556010106	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
929556010107	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
929556010108	active site
929556010109	catalytic residues [active]
929556010110	metal binding site [ion binding]; metal-binding site
929556010111	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
929556010112	antiporter inner membrane protein; Provisional; Region: PRK11670
929556010113	Domain of unknown function DUF59; Region: DUF59; pfam01883
929556010114	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
929556010115	Walker A motif; other site
929556010116	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
929556010117	active site
929556010118	Int/Topo IB signature motif; other site
929556010119	DNA binding site [nucleotide binding]
929556010120	Transglycosylase; Region: Transgly; pfam00912
929556010121	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556010122	Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism]; Region: LeuA; COG0119
929556010123	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
929556010124	active site
929556010125	catalytic residues [active]
929556010126	metal binding site [ion binding]; metal-binding site
929556010127	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
929556010128	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
929556010129	substrate binding site [chemical binding]; other site
929556010130	ligand binding site [chemical binding]; other site
929556010131	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
929556010132	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
929556010133	substrate binding site [chemical binding]; other site
929556010134	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
929556010135	tartrate dehydrogenase; Region: TTC; TIGR02089
929556010136	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556010137	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
929556010138	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
929556010139	N-terminal plug; other site
929556010140	ligand-binding site [chemical binding]; other site
929556010141	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
929556010142	active site
929556010143	catalytic residues [active]
929556010144	Signal peptidase I [Intracellular trafficking and secretion]; Region: LepB; COG0681
929556010145	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
929556010146	Catalytic site [active]
929556010147	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
929556010148	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
929556010149	galactokinase; Provisional; Region: PRK05322
929556010150	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
929556010151	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
929556010152	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
929556010153	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
929556010154	active site
929556010155	catalytic residues [active]
929556010156	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
929556010157	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
929556010158	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
929556010159	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
929556010160	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
929556010161	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
929556010162	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
929556010163	DNA binding site [nucleotide binding]
929556010164	active site
929556010165	futalosine nucleosidase; Region: fut_nucase; TIGR03664
929556010166	Menaquinone biosynthesis; Region: VitK2_biosynth; cl17475
929556010167	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929556010168	NAD(P) binding site [chemical binding]; other site
929556010169	Peptidase family M23; Region: Peptidase_M23; pfam01551
929556010170	excinuclease ABC subunit B; Provisional; Region: PRK05298
929556010171	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929556010172	ATP binding site [chemical binding]; other site
929556010173	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929556010174	nucleotide binding region [chemical binding]; other site
929556010175	ATP-binding site [chemical binding]; other site
929556010176	Ultra-violet resistance protein B; Region: UvrB; pfam12344
929556010177	UvrB/uvrC motif; Region: UVR; pfam02151
929556010178	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929556010179	active site
929556010180	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
929556010181	Site-specific recombinase; Region: SpecificRecomb; cl15411
929556010182	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
929556010183	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
929556010184	NADP binding site [chemical binding]; other site
929556010185	active site
929556010186	putative substrate binding site [chemical binding]; other site
929556010187	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
929556010188	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929556010189	motif II; other site
929556010190	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
929556010191	Chloramphenicol acetyltransferase; Region: CAT; smart01059
929556010192	YtxH-like protein; Region: YtxH; pfam12732
929556010193	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
929556010194	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
929556010195	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
929556010196	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556010197	ligand binding site [chemical binding]; other site
929556010198	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
929556010199	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
929556010200	putative active site [active]
929556010201	heme pocket [chemical binding]; other site
929556010202	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
929556010203	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
929556010204	putative active site [active]
929556010205	heme pocket [chemical binding]; other site
929556010206	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556010207	dimer interface [polypeptide binding]; other site
929556010208	phosphorylation site [posttranslational modification]
929556010209	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556010210	ATP binding site [chemical binding]; other site
929556010211	G-X-G motif; other site
929556010212	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
929556010213	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556010214	active site
929556010215	phosphorylation site [posttranslational modification]
929556010216	intermolecular recognition site; other site
929556010217	dimerization interface [polypeptide binding]; other site
929556010218	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556010219	Walker A motif; other site
929556010220	ATP binding site [chemical binding]; other site
929556010221	Walker B motif; other site
929556010222	arginine finger; other site
929556010223	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
929556010224	Response regulator receiver domain; Region: Response_reg; pfam00072
929556010225	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556010226	active site
929556010227	phosphorylation site [posttranslational modification]
929556010228	intermolecular recognition site; other site
929556010229	dimerization interface [polypeptide binding]; other site
929556010230	AMP nucleosidase; Provisional; Region: PRK07115
929556010231	enoyl-CoA hydratase; Provisional; Region: PRK07658
929556010232	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
929556010233	substrate binding site [chemical binding]; other site
929556010234	oxyanion hole (OAH) forming residues; other site
929556010235	trimer interface [polypeptide binding]; other site
929556010236	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
929556010237	B12 binding site [chemical binding]; other site
929556010238	cobalt ligand [ion binding]; other site
929556010239	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
929556010240	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
929556010241	active site
929556010242	HIGH motif; other site
929556010243	nucleotide binding site [chemical binding]; other site
929556010244	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
929556010245	KMSKS motif; other site
929556010246	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
929556010247	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
929556010248	CoenzymeA binding site [chemical binding]; other site
929556010249	subunit interaction site [polypeptide binding]; other site
929556010250	PHB binding site; other site
929556010251	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
929556010252	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556010253	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556010254	DNA binding residues [nucleotide binding]
929556010255	Protein of unknown function (DUF2911); Region: DUF2911; pfam11138
929556010256	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
929556010257	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
929556010258	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
929556010259	periplasmic chaperone; Provisional; Region: PRK10780
929556010260	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
929556010261	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
929556010262	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
929556010263	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
929556010264	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
929556010265	ligand binding site [chemical binding]; other site
929556010266	Histidine kinase; Region: His_kinase; pfam06580
929556010267	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
929556010268	Mg2+ binding site [ion binding]; other site
929556010269	G-X-G motif; other site
929556010270	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
929556010271	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556010272	active site
929556010273	phosphorylation site [posttranslational modification]
929556010274	intermolecular recognition site; other site
929556010275	dimerization interface [polypeptide binding]; other site
929556010276	LytTr DNA-binding domain; Region: LytTR; smart00850
929556010277	Methyltransferase domain; Region: Methyltransf_31; pfam13847
929556010278	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556010279	S-adenosylmethionine binding site [chemical binding]; other site
929556010280	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
929556010281	efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845
929556010282	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
929556010283	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
929556010284	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
929556010285	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556010286	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556010287	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556010288	Prokaryotic RING finger family 4; Region: Prok-RING_4; pfam14447
929556010289	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cl17565
929556010290	putative metal binding site [ion binding]; other site
929556010291	CsbD-like; Region: CsbD; cl17424
929556010292	ATP-dependent Clp protease adaptor protein ClpS; Region: ClpS; pfam02617
929556010293	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
929556010294	C-terminal peptidase (prc); Region: prc; TIGR00225
929556010295	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
929556010296	protein binding site [polypeptide binding]; other site
929556010297	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
929556010298	Catalytic dyad [active]
929556010299	Elongation factor G (EF-G) family; Region: EF-G_bact; cd04170
929556010300	elongation factor G; Reviewed; Region: PRK12740
929556010301	G1 box; other site
929556010302	putative GEF interaction site [polypeptide binding]; other site
929556010303	GTP/Mg2+ binding site [chemical binding]; other site
929556010304	Switch I region; other site
929556010305	G2 box; other site
929556010306	G3 box; other site
929556010307	Switch II region; other site
929556010308	G4 box; other site
929556010309	G5 box; other site
929556010310	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
929556010311	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
929556010312	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
929556010313	NlpC/P60 family; Region: NLPC_P60; pfam00877
929556010314	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
929556010315	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
929556010316	tetramer interface [polypeptide binding]; other site
929556010317	TPP-binding site [chemical binding]; other site
929556010318	heterodimer interface [polypeptide binding]; other site
929556010319	phosphorylation loop region [posttranslational modification]
929556010320	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
929556010321	E3 interaction surface; other site
929556010322	lipoyl attachment site [posttranslational modification]; other site
929556010323	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
929556010324	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
929556010325	E3 interaction surface; other site
929556010326	lipoyl attachment site [posttranslational modification]; other site
929556010327	e3 binding domain; Region: E3_binding; pfam02817
929556010328	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
929556010329	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
929556010330	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
929556010331	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
929556010332	aldehyde dehydrogenase family 7 member; Region: PLN02315
929556010333	NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B; Region: ALDH_F7_AASADH; cd07130
929556010334	tetrameric interface [polypeptide binding]; other site
929556010335	NAD binding site [chemical binding]; other site
929556010336	catalytic residues [active]
929556010337	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
929556010338	Low molecular weight phosphatase family; Region: LMWPc; cd00115
929556010339	active site
929556010340	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
929556010341	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
929556010342	dimer interface [polypeptide binding]; other site
929556010343	motif 1; other site
929556010344	active site
929556010345	motif 2; other site
929556010346	motif 3; other site
929556010347	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
929556010348	anticodon binding site; other site
929556010349	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
929556010350	Protein of unknown function DUF58; Region: DUF58; pfam01882
929556010351	MoxR-like ATPases [General function prediction only]; Region: COG0714
929556010352	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
929556010353	Walker A motif; other site
929556010354	ATP binding site [chemical binding]; other site
929556010355	Walker B motif; other site
929556010356	arginine finger; other site
929556010357	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
929556010358	Uncharacterized protein family (UPF0259); Region: UPF0259; cl11642
929556010359	Integral membrane protein DUF95; Region: DUF95; pfam01944
929556010360	RDD family; Region: RDD; pfam06271
929556010361	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
929556010362	four helix bundle protein; Region: TIGR02436
929556010363	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
929556010364	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
929556010365	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
929556010366	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
929556010367	putative catalytic residues [active]
929556010368	putative nucleotide binding site [chemical binding]; other site
929556010369	putative aspartate binding site [chemical binding]; other site
929556010370	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
929556010371	dimer interface [polypeptide binding]; other site
929556010372	putative threonine allosteric regulatory site; other site
929556010373	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
929556010374	putative threonine allosteric regulatory site; other site
929556010375	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
929556010376	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
929556010377	homoserine kinase; Provisional; Region: PRK01212
929556010378	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
929556010379	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
929556010380	threonine synthase; Validated; Region: PRK09225
929556010381	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
929556010382	catalytic residue [active]
929556010383	C-terminal processing peptidase-like; serine protease family S41; Region: Peptidase_S41_CPP_like; cd07561
929556010384	Catalytic dyad [active]
929556010385	fumarate hydratase; Reviewed; Region: fumC; PRK00485
929556010386	Class II fumarases; Region: Fumarase_classII; cd01362
929556010387	active site
929556010388	tetramer interface [polypeptide binding]; other site
929556010389	S1/P1 nucleases and related enzymes; Region: S1-P1_nuclease; cd11010
929556010390	active site
929556010391	Zn binding site [ion binding]; other site
929556010392	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556010393	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556010394	binding surface
929556010395	TPR motif; other site
929556010396	TPR repeat; Region: TPR_11; pfam13414
929556010397	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556010398	binding surface
929556010399	TPR motif; other site
929556010400	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556010401	TPR repeat; Region: TPR_11; pfam13414
929556010402	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556010403	binding surface
929556010404	TPR motif; other site
929556010405	Tetratricopeptide repeat; Region: TPR_12; pfam13424
929556010406	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556010407	binding surface
929556010408	TPR motif; other site
929556010409	TPR repeat; Region: TPR_11; pfam13414
929556010410	(2R)-phospho-3-sulfolactate synthase (ComA); Region: ComA; pfam02679
929556010411	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
929556010412	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
929556010413	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
929556010414	shikimate binding site; other site
929556010415	NAD(P) binding site [chemical binding]; other site
929556010416	gliding motility-associated lipoprotein GldD; Region: GldD_lipo; TIGR03512
929556010417	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
929556010418	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
929556010419	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556010420	FtsX-like permease family; Region: FtsX; pfam02687
929556010421	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
929556010422	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
929556010423	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
929556010424	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
929556010425	Coenzyme A binding pocket [chemical binding]; other site
929556010426	Protein of unknown function DUF115; Region: MAF_flag10; cl17471
929556010427	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556010428	Methyltransferase domain; Region: Methyltransf_23; pfam13489
929556010429	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
929556010430	This family is most closely related to the GT1 family of glycosyltransferases. wcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis; Region: GT1_wcfI_like; cd03825
929556010431	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
929556010432	metal-binding site
929556010433	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
929556010434	exodeoxyribonuclease X; Provisional; Region: PRK07983
929556010435	L,D-transpeptidase catalytic domain; Region: YkuD_2; pfam13645
929556010436	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2989
929556010437	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
929556010438	transaminase; Validated; Region: PRK07324
929556010439	MutS domain III; Region: MutS_III; cl17822
929556010440	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556010441	Walker A/P-loop; other site
929556010442	ATP binding site [chemical binding]; other site
929556010443	Q-loop/lid; other site
929556010444	ABC transporter signature motif; other site
929556010445	Walker B; other site
929556010446	D-loop; other site
929556010447	H-loop/switch region; other site
929556010448	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
929556010449	GTP-binding protein TypA/BipA; Region: TypA_BipA; TIGR01394
929556010450	G1 box; other site
929556010451	putative GEF interaction site [polypeptide binding]; other site
929556010452	GTP/Mg2+ binding site [chemical binding]; other site
929556010453	Switch I region; other site
929556010454	G2 box; other site
929556010455	G3 box; other site
929556010456	Switch II region; other site
929556010457	G4 box; other site
929556010458	G5 box; other site
929556010459	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
929556010460	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
929556010461	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
929556010462	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
929556010463	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
929556010464	homotrimer interaction site [polypeptide binding]; other site
929556010465	zinc binding site [ion binding]; other site
929556010466	CDP-binding sites; other site
929556010467	gliding motility-associated lipoprotein GldJ; Region: GldJ; TIGR03524
929556010468	gliding motility-associated lipoprotein GldJ; Region: GldJ_short; TIGR03530
929556010469	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
929556010470	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
929556010471	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
929556010472	Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483
929556010473	catalytic motif [active]
929556010474	Catalytic residue [active]
929556010475	Cellular and retroviral pepsin-like aspartate proteases; Region: pepsin_retropepsin_like; cl11403
929556010476	Domain of unknown function (DUF4269); Region: DUF4269; pfam14091
929556010477	Short C-terminal domain; Region: SHOCT; pfam09851
929556010478	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
929556010479	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
929556010480	Protein of unknown function (DUF1304); Region: DUF1304; pfam06993
929556010481	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
929556010482	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
929556010483	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
929556010484	homodecamer interface [polypeptide binding]; other site
929556010485	GTP cyclohydrolase I; Provisional; Region: PLN03044
929556010486	active site
929556010487	putative catalytic site residues [active]
929556010488	zinc binding site [ion binding]; other site
929556010489	GTP-CH-I/GFRP interaction surface; other site
929556010490	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
929556010491	active site
929556010492	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
929556010493	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
929556010494	motif II; other site
929556010495	DinB superfamily; Region: DinB_2; pfam12867
929556010496	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
929556010497	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
929556010498	putative active site [active]
929556010499	putative metal binding site [ion binding]; other site
929556010500	Glycosyl transferase family 1; Region: Glyco_trans_1_3; pfam13528
929556010501	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
929556010502	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
929556010503	putative active site [active]
929556010504	catalytic triad [active]
929556010505	Type III pantothenate kinase; Region: Pan_kinase; cl17198
929556010506	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
929556010507	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
929556010508	SurA N-terminal domain; Region: SurA_N_3; cl07813
929556010509	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
929556010510	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
929556010511	Protein of unknown function (DUF2480); Region: DUF2480; pfam10652
929556010512	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
929556010513	The Phox Homology domain, a phosphoinositide binding module; Region: PX_domain; cl02563
929556010514	Protein of unknown function (DUF3109); Region: DUF3109; pfam11307
929556010515	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
929556010516	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
929556010517	substrate binding site; other site
929556010518	tetramer interface; other site
929556010519	bifunctional phosphoglucose/phosphomannose isomerase; Validated; Region: PRK08674
929556010520	The members of this protein family contain the SIS (Sugar ISomerase) domain and have both the phosphoglucose isomerase (PGI) and the phosphomannose isomerase (PMI) functions. These functions catalyze the reversible reactions of glucose 6-phosphate to...; Region: SIS_PGI_PMI_1; cd05017
929556010521	dimer interface [polypeptide binding]; other site
929556010522	active site
929556010523	The members of this protein family contain the SIS (Sugar ISomerase) domain and have both the phosphoglucose isomerase (PGI) and the phosphomannose isomerase (PMI) functions. These functions catalyze the reversible reactions of glucose 6-phosphate to...; Region: SIS_PGI_PMI_2; cd05637
929556010524	dimer interface [polypeptide binding]; other site
929556010525	active site
929556010526	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
929556010527	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
929556010528	NADP-binding site; other site
929556010529	homotetramer interface [polypeptide binding]; other site
929556010530	substrate binding site [chemical binding]; other site
929556010531	homodimer interface [polypeptide binding]; other site
929556010532	active site
929556010533	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
929556010534	polysaccharide export protein EpsE; Region: EpsE; TIGR03028
929556010535	SLBB domain; Region: SLBB; pfam10531
929556010536	SLBB domain; Region: SLBB; pfam10531
929556010537	SLBB domain; Region: SLBB; pfam10531
929556010538	polysaccharide export protein EpsE; Region: EpsE; TIGR03028
929556010539	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
929556010540	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
929556010541	NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family; Region: EDH_00030; TIGR04180
929556010542	NAD binding site [chemical binding]; other site
929556010543	substrate binding site [chemical binding]; other site
929556010544	active site
929556010545	aminotransferase, LLPSF_NHT_00031 family; Region: NHT_00031; TIGR04181
929556010546	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
929556010547	inhibitor-cofactor binding pocket; inhibition site
929556010548	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556010549	catalytic residue [active]
929556010550	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
929556010551	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
929556010552	putative trimer interface [polypeptide binding]; other site
929556010553	putative CoA binding site [chemical binding]; other site
929556010554	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
929556010555	NeuB family; Region: NeuB; pfam03102
929556010556	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
929556010557	NeuB binding interface [polypeptide binding]; other site
929556010558	putative substrate binding site [chemical binding]; other site
929556010559	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
929556010560	UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; Region: NeuC_NnaA; TIGR03568
929556010561	active site
929556010562	homodimer interface [polypeptide binding]; other site
929556010563	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain associated with the NTP (Nucleotidyl transferase) domain downstream. CBS is a small domain originally identified in cystathionine beta-synthase and subsequently...; Region: CBS_pair_NTP_transferase_assoc; cd04607
929556010564	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
929556010565	NTP_trnasferase_like_2 is a member of the nucleotidyl transferase family; Region: NTP_transferase_like_2; cd06426
929556010566	Substrate binding site; other site
929556010567	metal-binding site
929556010568	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
929556010569	ligand binding site; other site
929556010570	tetramer interface; other site
929556010571	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
929556010572	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
929556010573	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
929556010574	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
929556010575	active site
929556010576	UDP-N-acetylglucosamine 2-epimerase; Region: Epimerase_2; pfam02350
929556010577	homodimer interface [polypeptide binding]; other site
929556010578	WxcM-like, C-terminal; Region: FdtA; pfam05523
929556010579	WxcM-like, C-terminal; Region: FdtA; pfam05523
929556010580	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
929556010581	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
929556010582	putative trimer interface [polypeptide binding]; other site
929556010583	putative active site [active]
929556010584	putative substrate binding site [chemical binding]; other site
929556010585	putative CoA binding site [chemical binding]; other site
929556010586	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
929556010587	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
929556010588	inhibitor-cofactor binding pocket; inhibition site
929556010589	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556010590	catalytic residue [active]
929556010591	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
929556010592	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
929556010593	trimer interface [polypeptide binding]; other site
929556010594	active site
929556010595	substrate binding site [chemical binding]; other site
929556010596	CoA binding site [chemical binding]; other site
929556010597	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
929556010598	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
929556010599	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
929556010600	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
929556010601	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
929556010602	nitrous oxide reductase family maturation protein NosD; Region: NosD_copper_fam; TIGR04247
929556010603	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
929556010604	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
929556010605	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
929556010606	active site
929556010607	putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ; Provisional; Region: PRK09677
929556010608	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
929556010609	trimer interface [polypeptide binding]; other site
929556010610	active site
929556010611	substrate binding site [chemical binding]; other site
929556010612	CoA binding site [chemical binding]; other site
929556010613	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
929556010614	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929556010615	NAD(P) binding site [chemical binding]; other site
929556010616	active site
929556010617	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
929556010618	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
929556010619	Mg++ binding site [ion binding]; other site
929556010620	putative catalytic motif [active]
929556010621	substrate binding site [chemical binding]; other site
929556010622	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
929556010623	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
929556010624	TPP-binding site; other site
929556010625	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
929556010626	PYR/PP interface [polypeptide binding]; other site
929556010627	dimer interface [polypeptide binding]; other site
929556010628	TPP binding site [chemical binding]; other site
929556010629	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
929556010630	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
929556010631	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
929556010632	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
929556010633	ScpA/B protein; Region: ScpA_ScpB; cl00598
929556010634	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
929556010635	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
929556010636	dimer interface [polypeptide binding]; other site
929556010637	active site
929556010638	glycine-pyridoxal phosphate binding site [chemical binding]; other site
929556010639	folate binding site [chemical binding]; other site
929556010640	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
929556010641	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
929556010642	active site
929556010643	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
929556010644	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929556010645	FeS/SAM binding site; other site
929556010646	chlorohydrolase; Provisional; Region: PRK07213
929556010647	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
929556010648	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
929556010649	active site
929556010650	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
929556010651	isopentenyl-diphosphate delta-isomerase, type 1; Region: IPP_isom_1; TIGR02150
929556010652	active site
929556010653	metal binding site [ion binding]; metal-binding site
929556010654	nudix motif; other site
929556010655	Acylphosphatase; Region: Acylphosphatase; pfam00708
929556010656	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
929556010657	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
929556010658	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
929556010659	trimer interface [polypeptide binding]; other site
929556010660	active site
929556010661	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556010662	binding surface
929556010663	TPR motif; other site
929556010664	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556010665	TPR motif; other site
929556010666	binding surface
929556010667	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556010668	binding surface
929556010669	TPR motif; other site
929556010670	TPR repeat; Region: TPR_11; pfam13414
929556010671	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556010672	binding surface
929556010673	TPR motif; other site
929556010674	Domain of unknown function (DUF4292); Region: DUF4292; pfam14125
929556010675	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
929556010676	Peptidase family M23; Region: Peptidase_M23; pfam01551
929556010677	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
929556010678	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
929556010679	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
929556010680	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
929556010681	N-acetyl-D-glucosamine binding site [chemical binding]; other site
929556010682	catalytic residue [active]
929556010683	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
929556010684	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
929556010685	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
929556010686	Malic enzyme, N-terminal domain; Region: malic; pfam00390
929556010687	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
929556010688	putative NAD(P) binding site [chemical binding]; other site
929556010689	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
929556010690	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
929556010691	RuvA N terminal domain; Region: RuvA_N; pfam01330
929556010692	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
929556010693	cell surface protein SprA; Region: surface_SprA; TIGR04189
929556010694	Motility related/secretion protein; Region: SprA_N; pfam14349
929556010695	Motility related/secretion protein; Region: SprA_N; pfam14349
929556010696	Motility related/secretion protein; Region: SprA_N; pfam14349
929556010697	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
929556010698	lipoyl attachment site [posttranslational modification]; other site
929556010699	Predicted integral membrane protein [Function unknown]; Region: COG5652
929556010700	FeoA domain; Region: FeoA; pfam04023
929556010701	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
929556010702	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
929556010703	G1 box; other site
929556010704	GTP/Mg2+ binding site [chemical binding]; other site
929556010705	Switch I region; other site
929556010706	G2 box; other site
929556010707	G3 box; other site
929556010708	Switch II region; other site
929556010709	G4 box; other site
929556010710	G5 box; other site
929556010711	Nucleoside recognition; Region: Gate; pfam07670
929556010712	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
929556010713	Nucleoside recognition; Region: Gate; pfam07670
929556010714	SprT-like family; Region: SprT-like; pfam10263
929556010715	SprT homologues; Region: SprT; cl01182
929556010716	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_3; cd07820
929556010717	putative hydrophobic ligand binding site [chemical binding]; other site
929556010718	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
929556010719	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
929556010720	active site
929556010721	HIGH motif; other site
929556010722	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
929556010723	KMSKS motif; other site
929556010724	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
929556010725	tRNA binding surface [nucleotide binding]; other site
929556010726	anticodon binding site; other site
929556010727	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; uncharacterized family 2; Region: EEP-2; cd09084
929556010728	putative catalytic site [active]
929556010729	putative metal binding site [ion binding]; other site
929556010730	putative phosphate binding site [ion binding]; other site
929556010731	Rhomboid family; Region: Rhomboid; pfam01694
929556010732	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
929556010733	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
929556010734	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556010735	ATP binding site [chemical binding]; other site
929556010736	Mg2+ binding site [ion binding]; other site
929556010737	G-X-G motif; other site
929556010738	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
929556010739	ATP binding site [chemical binding]; other site
929556010740	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
929556010741	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
929556010742	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
929556010743	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
929556010744	Beta-lactamase; Region: Beta-lactamase; cl17358
929556010745	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA; Region: thiol_BshA; TIGR03999
929556010746	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_5; cd04962
929556010747	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
929556010748	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
929556010749	RNA binding surface [nucleotide binding]; other site
929556010750	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
929556010751	active site
929556010752	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
929556010753	N-acetyl-D-glucosamine binding site [chemical binding]; other site
929556010754	catalytic residue [active]
929556010755	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
929556010756	N-acetyl-D-glucosamine binding site [chemical binding]; other site
929556010757	catalytic residue [active]
929556010758	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556010759	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556010760	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
929556010761	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
929556010762	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
929556010763	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
929556010764	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
929556010765	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
929556010766	putative carbohydrate kinase; Provisional; Region: PRK10565
929556010767	YjeF-related protein N-terminus; Region: YjeF_N; pfam03853
929556010768	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
929556010769	putative substrate binding site [chemical binding]; other site
929556010770	putative ATP binding site [chemical binding]; other site
929556010771	putative anti-sigmaE protein; Provisional; Region: PRK13920
929556010772	Anti-sigma-K factor rskA; Region: RskA; pfam10099
929556010773	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
929556010774	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
929556010775	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
929556010776	DNA binding residues [nucleotide binding]
929556010777	lipoyl synthase; Provisional; Region: PRK05481
929556010778	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929556010779	FeS/SAM binding site; other site
929556010780	OsmC-like protein; Region: OsmC; pfam02566
929556010781	bacillithiol system protein YtxJ; Region: B_thiol_YtxJ; TIGR04019
929556010782	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
929556010783	homopentamer interface [polypeptide binding]; other site
929556010784	active site
929556010785	Uncharacterized protein conserved in bacteria (DUF2133); Region: DUF2133; pfam09976
929556010786	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
929556010787	recombination protein F; Reviewed; Region: recF; PRK00064
929556010788	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556010789	Walker A/P-loop; other site
929556010790	ATP binding site [chemical binding]; other site
929556010791	Q-loop/lid; other site
929556010792	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
929556010793	ABC transporter signature motif; other site
929556010794	Walker B; other site
929556010795	D-loop; other site
929556010796	H-loop/switch region; other site
929556010797	Protein of unknown function (DUF721); Region: DUF721; pfam05258
929556010798	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
929556010799	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
929556010800	ArsC family; Region: ArsC; pfam03960
929556010801	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
929556010802	active site
929556010803	multimer interface [polypeptide binding]; other site
929556010804	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
929556010805	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
929556010806	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
929556010807	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
929556010808	DHH family; Region: DHH; pfam01368
929556010809	DHHA1 domain; Region: DHHA1; pfam02272
929556010810	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
929556010811	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
929556010812	active site
929556010813	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
929556010814	active site
929556010815	homodimer interface [polypeptide binding]; other site
929556010816	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
929556010817	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556010818	active site
929556010819	phosphorylation site [posttranslational modification]
929556010820	intermolecular recognition site; other site
929556010821	dimerization interface [polypeptide binding]; other site
929556010822	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
929556010823	DNA binding site [nucleotide binding]
929556010824	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556010825	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
929556010826	dimerization interface [polypeptide binding]; other site
929556010827	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556010828	dimer interface [polypeptide binding]; other site
929556010829	phosphorylation site [posttranslational modification]
929556010830	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556010831	ATP binding site [chemical binding]; other site
929556010832	Mg2+ binding site [ion binding]; other site
929556010833	G-X-G motif; other site
929556010834	Outer membrane efflux protein; Region: OEP; pfam02321
929556010835	Outer membrane efflux protein; Region: OEP; pfam02321
929556010836	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
929556010837	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
929556010838	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556010839	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
929556010840	Bacterial SH3 domain; Region: SH3_3; cl17532
929556010841	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
929556010842	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
929556010843	substrate binding pocket [chemical binding]; other site
929556010844	chain length determination region; other site
929556010845	substrate-Mg2+ binding site; other site
929556010846	catalytic residues [active]
929556010847	aspartate-rich region 1; other site
929556010848	active site lid residues [active]
929556010849	aspartate-rich region 2; other site
929556010850	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
929556010851	ornithine aminotransferase; Region: Orn_aminotrans; TIGR01885
929556010852	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
929556010853	inhibitor-cofactor binding pocket; inhibition site
929556010854	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556010855	catalytic residue [active]
929556010856	Aspartate racemase [Cell envelope biogenesis, outer membrane]; Region: RacX; COG1794
929556010857	aspartate racemase; Region: asp_race; TIGR00035
929556010858	short chain dehydrogenase; Provisional; Region: PRK06181
929556010859	11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs; Region: 11beta-HSD1_like_SDR_c; cd05332
929556010860	NADP binding site [chemical binding]; other site
929556010861	homodimer interface [polypeptide binding]; other site
929556010862	substrate binding site [chemical binding]; other site
929556010863	active site
929556010864	GH3 auxin-responsive promoter; Region: GH3; pfam03321
929556010865	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
929556010866	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
929556010867	Walker A/P-loop; other site
929556010868	ATP binding site [chemical binding]; other site
929556010869	Q-loop/lid; other site
929556010870	ABC transporter signature motif; other site
929556010871	Walker B; other site
929556010872	D-loop; other site
929556010873	H-loop/switch region; other site
929556010874	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
929556010875	DHH family; Region: DHH; pfam01368
929556010876	DHHA1 domain; Region: DHHA1; pfam02272
929556010877	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
929556010878	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
929556010879	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
929556010880	dimer interface [polypeptide binding]; other site
929556010881	motif 1; other site
929556010882	active site
929556010883	motif 2; other site
929556010884	motif 3; other site
929556010885	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
929556010886	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
929556010887	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
929556010888	active site
929556010889	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
929556010890	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556010891	S-adenosylmethionine binding site [chemical binding]; other site
929556010892	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cl00309
929556010893	Transposase IS200 like; Region: Y1_Tnp; pfam01797
929556010894	peptidase T; Region: peptidase-T; TIGR01882
929556010895	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
929556010896	metal binding site [ion binding]; metal-binding site
929556010897	dimer interface [polypeptide binding]; other site
929556010898	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
929556010899	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
929556010900	ATP binding site [chemical binding]; other site
929556010901	putative Mg++ binding site [ion binding]; other site
929556010902	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
929556010903	nucleotide binding region [chemical binding]; other site
929556010904	ATP-binding site [chemical binding]; other site
929556010905	RQC domain; Region: RQC; pfam09382
929556010906	HRDC domain; Region: HRDC; pfam00570
929556010907	shikimate kinase; Reviewed; Region: aroK; PRK00131
929556010908	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
929556010909	ADP binding site [chemical binding]; other site
929556010910	magnesium binding site [ion binding]; other site
929556010911	putative shikimate binding site; other site
929556010912	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
929556010913	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
929556010914	dimer interface [polypeptide binding]; other site
929556010915	conserved gate region; other site
929556010916	putative PBP binding loops; other site
929556010917	ABC-ATPase subunit interface; other site
929556010918	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
929556010919	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
929556010920	FeS/SAM binding site; other site
929556010921	HemN C-terminal domain; Region: HemN_C; pfam06969
929556010922	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
929556010923	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
929556010924	active site
929556010925	catalytic tetrad [active]
929556010926	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
929556010927	di-heme enzyme, MXAN_0977 family; Region: MXAN_0977_Heme2; TIGR04039
929556010928	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
929556010929	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
929556010930	N-terminal plug; other site
929556010931	ligand-binding site [chemical binding]; other site
929556010932	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
929556010933	DoxX; Region: DoxX; pfam07681
929556010934	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
929556010935	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
929556010936	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
929556010937	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
929556010938	dihydropteroate synthase; Region: DHPS; TIGR01496
929556010939	substrate binding pocket [chemical binding]; other site
929556010940	dimer interface [polypeptide binding]; other site
929556010941	inhibitor binding site; inhibition site
929556010942	Uncharacterized conserved protein [Function unknown]; Region: COG1624
929556010943	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
929556010944	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
929556010945	Coenzyme A binding pocket [chemical binding]; other site
929556010946	Predicted amidohydrolase [General function prediction only]; Region: COG0388
929556010947	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
929556010948	putative active site [active]
929556010949	catalytic triad [active]
929556010950	putative dimer interface [polypeptide binding]; other site
929556010951	Major Facilitator Superfamily; Region: MFS_1; pfam07690
929556010952	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
929556010953	phosphonate utilization associated transcriptional regulator; Region: phnR_burk; TIGR03338
929556010954	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
929556010955	DNA-binding site [nucleotide binding]; DNA binding site
929556010956	FCD domain; Region: FCD; pfam07729
929556010957	bacillithiol system oxidoreductase, YphP/YqiW family; Region: YphP_YqiW; TIGR04191
929556010958	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
929556010959	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
929556010960	putative active site [active]
929556010961	catalytic site [active]
929556010962	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
929556010963	putative active site [active]
929556010964	catalytic site [active]
929556010965	SnoaL-like domain; Region: SnoaL_2; pfam12680
929556010966	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
929556010967	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
929556010968	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
929556010969	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
929556010970	homotetramer interface [polypeptide binding]; other site
929556010971	ligand binding site [chemical binding]; other site
929556010972	catalytic site [active]
929556010973	NAD binding site [chemical binding]; other site
929556010974	TPR repeat; Region: TPR_11; pfam13414
929556010975	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
929556010976	TPR motif; other site
929556010977	isocitrate lyase; Provisional; Region: PRK15063
929556010978	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
929556010979	tetramer interface [polypeptide binding]; other site
929556010980	active site
929556010981	Mg2+/Mn2+ binding site [ion binding]; other site
929556010982	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
929556010983	malate synthase A; Region: malate_syn_A; TIGR01344
929556010984	active site
929556010985	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929556010986	non-specific DNA binding site [nucleotide binding]; other site
929556010987	salt bridge; other site
929556010988	sequence-specific DNA binding site [nucleotide binding]; other site
929556010989	Domain of unknown function (DUF955); Region: DUF955; cl01076
929556010990	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
929556010991	active site
929556010992	hydrophilic channel; other site
929556010993	dimerization interface [polypeptide binding]; other site
929556010994	catalytic residues [active]
929556010995	active site lid [active]
929556010996	CpeT/CpcT family (DUF1001); Region: CpeT; pfam06206
929556010997	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
929556010998	active site
929556010999	dimer interfaces [polypeptide binding]; other site
929556011000	catalytic residues [active]
929556011001	glycine dehydrogenase; Provisional; Region: PRK05367
929556011002	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
929556011003	tetramer interface [polypeptide binding]; other site
929556011004	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556011005	catalytic residue [active]
929556011006	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
929556011007	tetramer interface [polypeptide binding]; other site
929556011008	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556011009	catalytic residue [active]
929556011010	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
929556011011	non-specific DNA binding site [nucleotide binding]; other site
929556011012	salt bridge; other site
929556011013	sequence-specific DNA binding site [nucleotide binding]; other site
929556011014	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
929556011015	catalytic core [active]
929556011016	Methyltransferase domain; Region: Methyltransf_31; pfam13847
929556011017	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
929556011018	S-adenosylmethionine binding site [chemical binding]; other site
929556011019	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
929556011020	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556011021	active site
929556011022	phosphorylation site [posttranslational modification]
929556011023	intermolecular recognition site; other site
929556011024	dimerization interface [polypeptide binding]; other site
929556011025	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
929556011026	DNA binding residues [nucleotide binding]
929556011027	dimerization interface [polypeptide binding]; other site
929556011028	7TMR-DISM extracellular 2; Region: 7TMR-DISMED2; pfam07696
929556011029	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
929556011030	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
929556011031	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556011032	ATP binding site [chemical binding]; other site
929556011033	Mg2+ binding site [ion binding]; other site
929556011034	G-X-G motif; other site
929556011035	YceI-like domain; Region: YceI; smart00867
929556011036	YceI-like domain; Region: YceI; pfam04264
929556011037	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
929556011038	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
929556011039	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
929556011040	substrate-cofactor binding pocket; other site
929556011041	pyridoxal 5'-phosphate binding site [chemical binding]; other site
929556011042	catalytic residue [active]
929556011043	Cna protein B-type domain; Region: Cna_B_2; pfam13715
929556011044	Protein of unknown function, DUF486; Region: DUF486; cl01236
929556011045	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
929556011046	Domain of unknown function (DUF4281); Region: DUF4281; pfam14108
929556011047	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
929556011048	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
929556011049	NAD(P) binding site [chemical binding]; other site
929556011050	active site
929556011051	Lamin Tail Domain; Region: LTD; pfam00932
929556011052	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
929556011053	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
929556011054	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
929556011055	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
929556011056	AAA domain; Region: AAA_28; pfam13521
929556011057	DinB superfamily; Region: DinB_2; pfam12867
929556011058	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
929556011059	active site
929556011060	LytB protein; Region: LYTB; cl00507
929556011061	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
929556011062	ferrochelatase; Reviewed; Region: hemH; PRK00035
929556011063	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
929556011064	C-terminal domain interface [polypeptide binding]; other site
929556011065	active site
929556011066	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
929556011067	active site
929556011068	N-terminal domain interface [polypeptide binding]; other site
929556011069	PAS domain S-box; Region: sensory_box; TIGR00229
929556011070	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
929556011071	PAS domain; Region: PAS_9; pfam13426
929556011072	putative active site [active]
929556011073	heme pocket [chemical binding]; other site
929556011074	PAS domain; Region: PAS_9; pfam13426
929556011075	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
929556011076	dimer interface [polypeptide binding]; other site
929556011077	phosphorylation site [posttranslational modification]
929556011078	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
929556011079	ATP binding site [chemical binding]; other site
929556011080	Mg2+ binding site [ion binding]; other site
929556011081	G-X-G motif; other site
929556011082	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
929556011083	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
929556011084	active site
929556011085	phosphorylation site [posttranslational modification]
929556011086	intermolecular recognition site; other site
929556011087	dimerization interface [polypeptide binding]; other site
929556011088	3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane]; Region: KdtA; COG1519
929556011089	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
929556011090	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
929556011091	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
929556011092	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
929556011093	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
929556011094	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
929556011095	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
929556011096	NAD binding site [chemical binding]; other site
929556011097	homodimer interface [polypeptide binding]; other site
929556011098	active site
929556011099	substrate binding site [chemical binding]; other site
929556011100	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
929556011101	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
929556011102	NAD binding site [chemical binding]; other site
929556011103	substrate binding site [chemical binding]; other site
929556011104	homodimer interface [polypeptide binding]; other site
929556011105	active site
929556011106	Surface antigen; Region: Bac_surface_Ag; pfam01103
929556011107	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
929556011108	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
929556011109	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
929556011110	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
929556011111	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
929556011112	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
929556011113	HlyD family secretion protein; Region: HlyD_3; pfam13437
929556011114	Outer membrane efflux protein; Region: OEP; pfam02321
929556011115	Outer membrane efflux protein; Region: OEP; pfam02321
929556011116	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
929556011117	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
929556011118	FtsX-like permease family; Region: FtsX; pfam02687
929556011119	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
929556011120	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, isobutyryl-CoA mutase (ICM)-like subfamily; contains archaeal and bacterial proteins similar to the large subunit of Streptomyces cinnamonensis coenzyme B12-dependent ICM. ICM...; Region: MM_CoA_mutase_ICM_like; cd03680