-- dump date 20140620_073537 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_184912.1 57651109 3236025 544..1905 1 NC_002951.2 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1905 dnaA 3236025 dnaA Staphylococcus aureus subsp. aureus COL chromosomal replication initiation protein YP_184912.1 544 D 93062 CDS YP_184913.1 57651110 3236026 2183..3316 1 NC_002951.2 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 3316 dnaN 3236026 dnaN Staphylococcus aureus subsp. aureus COL DNA polymerase III subunit beta YP_184913.1 2183 D 93062 CDS YP_184914.1 57651111 3236184 3697..3942 1 NC_002951.2 hypothetical protein 3942 3236184 SACOL0003 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184914.1 3697 D 93062 CDS YP_184915.1 57651112 3236185 3939..5051 1 NC_002951.2 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 5051 recF 3236185 recF Staphylococcus aureus subsp. aureus COL recombination protein F YP_184915.1 3939 D 93062 CDS YP_184916.1 57651113 3236186 5061..6995 1 NC_002951.2 identified by match to protein family HMM PF00204; match to protein family HMM PF00986; match to protein family HMM PF01751; match to protein family HMM PF02518; match to protein family HMM TIGR01059; DNA gyrase, B subunit 6995 gyrB 3236186 gyrB Staphylococcus aureus subsp. aureus COL DNA gyrase, B subunit YP_184916.1 5061 D 93062 CDS YP_184917.1 57651114 3236187 7032..9695 1 NC_002951.2 identified by similarity to SP:P20831; match to protein family HMM PF00521; match to protein family HMM PF03989; match to protein family HMM TIGR01063; DNA gyrase, A subunit 9695 gyrA 3236187 gyrA Staphylococcus aureus subsp. aureus COL DNA gyrase, A subunit YP_184917.1 7032 D 93062 CDS YP_184918.1 57651115 3236407 complement(9782..10483) 1 NC_002951.2 identified by similarity to EGAD:21908; match to protein family HMM PF01256; hypothetical protein 10483 3236407 SACOL0007 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184918.1 9782 R 93062 CDS YP_184919.1 57651116 3236408 10920..12434 1 NC_002951.2 catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase 12434 hutH 3236408 hutH Staphylococcus aureus subsp. aureus COL histidine ammonia-lyase YP_184919.1 10920 D 93062 CDS YP_184920.1 57651117 3236409 12813..14099 1 NC_002951.2 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 14099 serS 3236409 serS Staphylococcus aureus subsp. aureus COL seryl-tRNA synthetase YP_184920.1 12813 D 93062 CDS YP_184921.1 57651118 3236410 14749..15444 1 NC_002951.2 identified by match to protein family HMM PF03591; hypothetical protein 15444 3236410 SACOL0010 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184921.1 14749 D 93062 CDS YP_184922.1 57651119 3236194 15441..15770 1 NC_002951.2 identified by similarity to GB:AAO03607.1; match to protein family HMM PF06063; hypothetical protein 15770 3236194 SACOL0011 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184922.1 15441 D 93062 CDS YP_184923.1 57651120 3236195 16112..17101 1 NC_002951.2 identified by match to protein family HMM PF00561; homoserine O-acetyltransferase 17101 3236195 SACOL0012 Staphylococcus aureus subsp. aureus COL homoserine O-acetyltransferase YP_184923.1 16112 D 93062 CDS YP_184924.1 57651121 3236196 17407..18330 1 NC_002951.2 hypothetical protein 18330 3236196 SACOL0013 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184924.1 17407 D 93062 CDS YP_184925.1 57651122 3236197 18345..20312 1 NC_002951.2 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; hypothetical protein 20312 3236197 SACOL0014 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184925.1 18345 D 93062 CDS YP_184926.1 57651123 3236535 20309..20755 1 NC_002951.2 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 20755 rplI 3236535 rplI Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L9 YP_184926.1 20309 D 93062 CDS YP_184927.1 57651124 3236536 20787..22187 1 NC_002951.2 identified by similarity to EGAD:21924; match to protein family HMM PF00772; match to protein family HMM PF03796; match to protein family HMM TIGR00665; replicative DNA helicase 22187 dnaB 3236536 dnaB Staphylococcus aureus subsp. aureus COL replicative DNA helicase YP_184927.1 20787 D 93062 CDS YP_184928.1 57651125 3236537 22263..22355 1 NC_002951.2 hypothetical protein 22355 3236537 SACOL0017 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184928.1 22263 D 93062 CDS YP_184929.1 57651126 3236538 22465..23748 1 NC_002951.2 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 23748 purA 3236538 purA Staphylococcus aureus subsp. aureus COL adenylosuccinate synthetase YP_184929.1 22465 D 93062 CDS YP_184930.1 57651127 3236559 24952..25653 1 NC_002951.2 identified by similarity to GP:5114230; similarity to OMNI:SA0019; match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator YycF 25653 yycF 3236559 yycF Staphylococcus aureus subsp. aureus COL DNA-binding response regulator YycF YP_184930.1 24952 D 93062 CDS YP_184931.1 57651128 3236560 25666..27492 1 NC_002951.2 identified by similarity to GP:5114231; similarity to OMNI:SA0020; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensory box histidine kinase YycG 27492 yycG 3236560 yycG Staphylococcus aureus subsp. aureus COL sensory box histidine kinase YycG YP_184931.1 25666 D 93062 CDS YP_184932.1 57651129 3236561 27485..28819 1 NC_002951.2 identified by similarity to GP:1064812; match to protein family HMM PF07435; hypothetical protein 28819 yycH 3236561 yycH Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184932.1 27485 D 93062 CDS YP_184933.1 57651130 3236735 28820..29608 1 NC_002951.2 hypothetical protein 29608 yycI 3236735 yycI Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184933.1 28820 D 93062 CDS YP_184934.1 57651131 3236736 29998..30798 1 NC_002951.2 identified by match to protein family HMM PF00753; metallo-beta-lactamase YycJ 30798 yycJ 3236736 yycJ Staphylococcus aureus subsp. aureus COL metallo-beta-lactamase YycJ YP_184934.1 29998 D 93062 CDS YP_184935.1 57651132 3236737 31026..33344 1 NC_002951.2 identified by match to protein family HMM PF00149; match to protein family HMM PF00746; match to protein family HMM PF02872; match to protein family HMM TIGR01167; 5'-nucleotidase 33344 3236737 SACOL0024 Staphylococcus aureus subsp. aureus COL 5'-nucleotidase YP_184935.1 31026 D 93062 CDS YP_184936.1 57651133 3236738 complement(33576..34055) 1 NC_002951.2 hypothetical protein 34055 3236738 SACOL0025 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184936.1 33576 R 93062 CDS YP_184937.1 57651134 3236745 34372..35667 1 NC_002951.2 hypothetical protein 35667 3236745 SACOL0026 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184937.1 34372 D 93062 CDS YP_184938.1 57651135 3236746 36082..36321 1 NC_002951.2 hypothetical protein 36321 3236746 SACOL0027 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184938.1 36082 D 93062 CDS YP_184939.1 57651136 3236747 complement(36353..37027) 1 NC_002951.2 identified by similarity to SP:P19380; match to protein family HMM PF00665; IS431mec, transposase 37027 3236747 SACOL0028 Staphylococcus aureus subsp. aureus COL IS431mec, transposase YP_184939.1 36353 R 93062 CDS YP_184940.1 57651137 3236748 37285..37452 1 NC_002951.2 identified by similarity to GP:9937361; HMG-CoA synthase, truncation 37452 3236748 SACOL0029 Staphylococcus aureus subsp. aureus COL HMG-CoA synthase, truncation YP_184940.1 37285 D 93062 CDS YP_184941.1 57651382 3237118 37550..37780 1 NC_002951.2 hypothetical protein 37780 3237118 SACOL0030 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184941.1 37550 D 93062 CDS YP_184942.1 57651138 3236761 38329..39072 1 NC_002951.2 identified by similarity to EGAD:9350; similarity to EGAD:9938; match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase 39072 3236761 SACOL0031 Staphylococcus aureus subsp. aureus COL glycerophosphoryl diester phosphodiesterase YP_184942.1 38329 D 93062 CDS YP_184943.1 57651139 3236762 39169..39597 1 NC_002951.2 identified by match to protein family HMM PF01575; MaoC domain-containing protein 39597 maoC 3236762 maoC Staphylococcus aureus subsp. aureus COL MaoC domain-containing protein YP_184943.1 39169 D 93062 CDS YP_184944.1 57651140 3236763 complement(39643..41649) 1 NC_002951.2 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF05223; penicillin-binding protein 2' 41649 mecA 3236763 mecA Staphylococcus aureus subsp. aureus COL penicillin-binding protein 2' YP_184944.1 39643 R 93062 CDS YP_184945.1 57651141 3236764 41749..42735 1 NC_002951.2 identified by similarity to EGAD:24355; match to protein family HMM PF05569; methicillin-resistance MecR1 regulatory protein 42735 mecR1 3236764 mecR1 Staphylococcus aureus subsp. aureus COL methicillin-resistance MecR1 regulatory protein YP_184945.1 41749 D 93062 CDS YP_184946.1 57651142 3236765 42707..42967 1 NC_002951.2 hypothetical protein 42967 3236765 SACOL0035 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184946.1 42707 D 93062 CDS YP_184947.1 57651143 3236766 complement(42958..44481) 1 NC_002951.2 identified by match to protein family HMM PF01609; IS1272 transposase 44481 3236766 SACOL0036 Staphylococcus aureus subsp. aureus COL IS1272 transposase YP_184947.1 42958 R 93062 CDS YP_184948.1 57652407 3237004 complement(44617..45123) 1 NC_002951.2 identified by similarity to GB:AAO03627.1; hypothetical protein 45123 3237004 SACOL0037 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184948.1 44617 R 93062 CDS YP_184949.1 57652408 3237005 complement(45138..45449) 1 NC_002951.2 identified by match to protein family HMM PF06124; hypothetical protein 45449 3237005 SACOL0038 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184949.1 45138 R 93062 CDS YP_184950.1 57652409 3237006 complement(45451..45543) 1 NC_002951.2 hypothetical protein 45543 3237006 SACOL0039 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184950.1 45451 R 93062 CDS YP_184951.1 57652410 3237007 complement(45536..45886) 1 NC_002951.2 identified by similarity to GB:AAO03652.1; match to protein family HMM PF06106; hypothetical protein 45886 3237007 SACOL0040 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184951.1 45536 R 93062 CDS YP_184952.1 57652411 3237009 complement(47998..49347) 1 NC_002951.2 identified by match to protein family HMM PF00239; match to protein family HMM PF07508; cassette chromosome recombinase A1 49347 ccrA1 3237009 ccrA1 Staphylococcus aureus subsp. aureus COL cassette chromosome recombinase A1 YP_184952.1 47998 R 93062 CDS YP_184953.1 57652412 3236995 complement(49535..51304) 1 NC_002951.2 identified by match to protein family HMM PF06048; hypothetical protein 51304 3236995 SACOL0043 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184953.1 49535 R 93062 CDS YP_184954.1 57652413 3236996 complement(51304..51600) 1 NC_002951.2 identified by match to protein family HMM PF07205; hypothetical protein 51600 3236996 SACOL0044 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184954.1 51304 R 93062 CDS YP_184955.1 57652414 3236997 51771..53348 1 NC_002951.2 hypothetical protein 53348 3236997 SACOL0045 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184955.1 51771 D 93062 CDS YP_184956.1 57652415 3236998 complement(53428..54756) 1 NC_002951.2 identified by match to protein family HMM PF00581; match to protein family HMM PF00753; metallo-beta-lactamase 54756 3236998 SACOL0046 Staphylococcus aureus subsp. aureus COL metallo-beta-lactamase YP_184956.1 53428 R 93062 CDS YP_184957.1 57652416 3236999 complement(54775..55842) 1 NC_002951.2 identified by match to protein family HMM PF00581; match to protein family HMM PF01206; hypothetical protein 55842 3236999 SACOL0047 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184957.1 54775 R 93062 CDS YP_184958.1 57652417 3237000 55981..56241 1 NC_002951.2 identified by match to protein family HMM PF02583; hypothetical protein 56241 3237000 SACOL0048 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184958.1 55981 D 93062 CDS YP_184959.1 57652418 3237001 56265..56996 1 NC_002951.2 identified by match to protein family HMM PF01925; hypothetical protein 56996 3237001 SACOL0049 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184959.1 56265 D 93062 CDS YP_184960.1 57652419 3237002 57212..61858 1 NC_002951.2 identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; methicillin-resistant surface protein 61858 pls 3237002 pls Staphylococcus aureus subsp. aureus COL methicillin-resistant surface protein YP_184960.1 57212 D 93062 CDS YP_184961.1 57652420 3236891 61982..63598 1 NC_002951.2 hypothetical protein 63598 3236891 SACOL0051 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184961.1 61982 D 93062 CDS YP_184962.1 57652421 3236892 complement(63758..65269) 1 NC_002951.2 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein 65269 3236892 SACOL0052 Staphylococcus aureus subsp. aureus COL glycosyl transferase, group 1 family protein YP_184962.1 63758 R 93062 CDS YP_184963.1 57652422 3236894 68407..68499 1 NC_002951.2 hypothetical protein 68499 3236894 SACOL0057 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184963.1 68407 D 93062 CDS YP_184964.1 57652423 3236895 68646..70391 1 NC_002951.2 hypothetical protein 70391 3236895 SACOL0058 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184964.1 68646 D 93062 CDS YP_184965.1 57652424 3236987 complement(70485..70937) 1 NC_002951.2 hypothetical protein 70937 3236987 SACOL0059 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184965.1 70485 R 93062 CDS YP_184966.1 57652425 3236988 complement(71152..71907) 1 NC_002951.2 identified by match to protein family HMM PF01925; hypothetical protein 71907 3236988 SACOL0061 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184966.1 71152 R 93062 CDS YP_184967.1 57652426 3236883 complement(71907..72167) 1 NC_002951.2 identified by match to protein family HMM PF02583; hypothetical protein 72167 3236883 SACOL0062 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184967.1 71907 R 93062 CDS YP_184968.1 57652427 3236884 72304..73371 1 NC_002951.2 identified by match to protein family HMM PF00581; match to protein family HMM PF01206; hypothetical protein 73371 3236884 SACOL0063 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184968.1 72304 D 93062 CDS YP_184969.1 57652428 3236885 73402..74736 1 NC_002951.2 identified by match to protein family HMM PF00581; match to protein family HMM PF00753; metallo-beta-lactamase 74736 3236885 SACOL0064 Staphylococcus aureus subsp. aureus COL metallo-beta-lactamase YP_184969.1 73402 D 93062 CDS YP_184970.1 57652429 3236886 74755..75948 1 NC_002951.2 hypothetical protein 75948 3236886 SACOL0065 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184970.1 74755 D 93062 CDS YP_184971.1 57652430 3236887 complement(76215..76316) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH0416; hypothetical protein 76316 3236887 SACOL0066 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184971.1 76215 R 93062 CDS YP_184972.1 57652431 3236888 complement(76615..77547) 1 NC_002951.2 identified by similarity to EGAD:108206; match to protein family HMM PF01207; hypothetical protein 77547 3236888 SACOL0067 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184972.1 76615 R 93062 CDS YP_184973.1 57652432 3236889 77910..78113 1 NC_002951.2 hypothetical protein 78113 3236889 SACOL0068 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184973.1 77910 D 93062 CDS YP_184974.1 57652433 3236890 78162..78458 1 NC_002951.2 identified by match to protein family HMM PF04993; hypothetical protein 78458 3236890 SACOL0069 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184974.1 78162 D 93062 CDS YP_184975.1 57652434 3236876 complement(78530..79750) 1 NC_002951.2 identified by match to protein family HMM PF07690; permease 79750 3236876 SACOL0070 Staphylococcus aureus subsp. aureus COL permease YP_184975.1 78530 R 93062 CDS YP_184976.1 57652435 3236877 complement(79743..80204) 1 NC_002951.2 identified by similarity to EGAD:107983; hypothetical protein 80204 3236877 SACOL0071 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184976.1 79743 R 93062 CDS YP_184977.1 57652436 3236878 80406..81266 1 NC_002951.2 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; hypothetical protein 81266 3236878 SACOL0072 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184977.1 80406 D 93062 CDS YP_184978.1 57652437 3236879 complement(81621..82154) 1 NC_002951.2 hypothetical protein 82154 3236879 SACOL0073 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184978.1 81621 R 93062 CDS YP_184979.1 57652438 3236880 82254..82988 1 NC_002951.2 identified by match to protein family HMM PF00126; hypothetical protein 82988 3236880 SACOL0074 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184979.1 82254 D 93062 CDS YP_184980.1 57652439 3236881 83422..84024 1 NC_002951.2 hypothetical protein 84024 3236881 SACOL0075 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184980.1 83422 D 93062 CDS YP_184981.1 57652440 3236882 84291..87443 1 NC_002951.2 hypothetical protein 87443 3236882 SACOL0076 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184981.1 84291 D 93062 CDS YP_184982.1 57652441 3236867 87500..87982 1 NC_002951.2 hypothetical protein 87982 3236867 SACOL0077 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184982.1 87500 D 93062 CDS YP_184983.1 57652442 3236868 88187..89173 1 NC_002951.2 identified by similarity to EGAD:20792; match to protein family HMM PF00388; 1-phosphatidylinositol phosphodiesterase 89173 plc 3236868 plc Staphylococcus aureus subsp. aureus COL 1-phosphatidylinositol phosphodiesterase YP_184983.1 88187 D 93062 CDS YP_184984.1 57652443 3236869 89394..90164 1 NC_002951.2 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742; hypothetical protein 90164 3236869 SACOL0079 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184984.1 89394 D 93062 CDS YP_184985.1 57652444 3236870 90216..90986 1 NC_002951.2 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742; hypothetical protein 90986 3236870 SACOL0080 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184985.1 90216 D 93062 CDS YP_184986.1 57652445 3236871 91050..91214 1 NC_002951.2 hypothetical protein 91214 3236871 SACOL0081 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184986.1 91050 D 93062 CDS YP_184987.1 57652446 3236872 91227..91823 1 NC_002951.2 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742; hypothetical protein 91823 3236872 SACOL0082 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184987.1 91227 D 93062 CDS YP_184988.1 57652447 3236873 91890..92657 1 NC_002951.2 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742; tandem lipoprotein 92657 3236873 SACOL0083 Staphylococcus aureus subsp. aureus COL tandem lipoprotein YP_184988.1 91890 D 93062 CDS YP_184989.1 57652448 3236874 92790..94988 1 NC_002951.2 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 94988 3236874 SACOL0084 Staphylococcus aureus subsp. aureus COL AraC family transcriptional regulator YP_184989.1 92790 D 93062 CDS YP_184990.1 57652449 3236859 95139..96317 1 NC_002951.2 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; M20/M25/M40 family peptidase 96317 3236859 SACOL0085 Staphylococcus aureus subsp. aureus COL M20/M25/M40 family peptidase YP_184990.1 95139 D 93062 CDS YP_184991.1 57652450 3236860 96319..97707 1 NC_002951.2 identified by match to protein family HMM PF07690; drug transporter 97707 3236860 SACOL0086 Staphylococcus aureus subsp. aureus COL drug transporter YP_184991.1 96319 D 93062 CDS YP_184992.1 57652451 3236861 97875..97982 1 NC_002951.2 hypothetical protein 97982 3236861 SACOL0087 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184992.1 97875 D 93062 CDS YP_184993.1 57652452 3236862 complement(98200..99861) 1 NC_002951.2 identified by match to protein family HMM PF02690; match to protein family HMM TIGR00704; Na/Pi cotransporter family protein 99861 3236862 SACOL0088 Staphylococcus aureus subsp. aureus COL Na/Pi cotransporter family protein YP_184993.1 98200 R 93062 CDS YP_184994.1 57652453 3236863 complement(100187..101962) 1 NC_002951.2 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; myosin-cross-reactive antigen 101962 3236863 SACOL0089 Staphylococcus aureus subsp. aureus COL myosin-cross-reactive antigen YP_184994.1 100187 R 93062 CDS YP_184995.1 57652454 3236864 complement(102136..103008) 1 NC_002951.2 identified by match to protein family HMM PF00892; integral membrane domain-containing protein 103008 3236864 SACOL0090 Staphylococcus aureus subsp. aureus COL integral membrane domain-containing protein YP_184995.1 102136 R 93062 CDS YP_184996.1 57652455 3236865 103121..104518 1 NC_002951.2 identified by match to protein family HMM PF00155; match to protein family HMM PF00392; GntR family transcriptional regulator 104518 3236865 SACOL0091 Staphylococcus aureus subsp. aureus COL GntR family transcriptional regulator YP_184996.1 103121 D 93062 CDS YP_184997.1 57652456 3236866 104708..105181 1 NC_002951.2 hypothetical protein 105181 3236866 SACOL0092 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_184997.1 104708 D 93062 CDS YP_184998.1 57652457 3236852 105443..107035 1 NC_002951.2 identified by similarity to EGAD:8633; match to protein family HMM PF02652; match to protein family HMM TIGR00795; L-lactate permease 107035 3236852 SACOL0093 Staphylococcus aureus subsp. aureus COL L-lactate permease YP_184998.1 105443 D 93062 CDS YP_184999.1 57652458 3236853 complement(107364..108890) 1 NC_002951.2 identified by similarity to SP:P02976; match to protein family HMM PF00746; match to protein family HMM PF01476; match to protein family HMM PF02216; match to protein family HMM PF03373; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; immunoglobulin G binding protein A precursor 108890 spa 3236853 spa Staphylococcus aureus subsp. aureus COL immunoglobulin G binding protein A precursor YP_184999.1 107364 R 93062 CDS YP_185000.1 57652459 3236854 complement(109311..110063) 1 NC_002951.2 identified by similarity to OMNI:SA0096; match to protein family HMM TIGR01889; accessory regulator S 110063 sarS 3236854 sarS Staphylococcus aureus subsp. aureus COL accessory regulator S YP_185000.1 109311 R 93062 CDS YP_185001.1 57652460 3236855 complement(110432..111430) 1 NC_002951.2 identified by match to protein family HMM PF01032; iron compound ABC transporter permease SirC 111430 sirC 3236855 sirC Staphylococcus aureus subsp. aureus COL iron compound ABC transporter permease SirC YP_185001.1 110432 R 93062 CDS YP_185002.1 57652461 3236856 complement(111427..112422) 1 NC_002951.2 identified by similarity to EGAD:9723; match to protein family HMM PF01032; iron compound ABC transporter permease SirB 112422 sirB 3236856 sirB Staphylococcus aureus subsp. aureus COL iron compound ABC transporter permease SirB YP_185002.1 111427 R 93062 CDS YP_185003.1 57652462 3236857 complement(112438..113430) 1 NC_002951.2 identified by similarity to EGAD:22102; match to protein family HMM PF01497; iron compound ABC transporter iron compound-binding protein SirA 113430 sirA 3236857 sirA Staphylococcus aureus subsp. aureus COL iron compound ABC transporter iron compound-binding protein SirA YP_185003.1 112438 R 93062 CDS YP_185004.1 57652463 3236858 113694..114641 1 NC_002951.2 identified by similarity to EGAD:101781; match to protein family HMM PF00291; cysteine synthase/cystathionine beta-synthase 114641 3236858 SACOL0100 Staphylococcus aureus subsp. aureus COL cysteine synthase/cystathionine beta-synthase YP_185004.1 113694 D 93062 CDS YP_185005.1 57652464 3236840 114650..115648 1 NC_002951.2 identified by match to protein family HMM PF02423; ornithine cyclodeaminase 115648 3236840 SACOL0101 Staphylococcus aureus subsp. aureus COL ornithine cyclodeaminase YP_185005.1 114650 D 93062 CDS YP_185006.1 57652465 3236841 115669..117423 1 NC_002951.2 identified by similarity to EGAD:97400; match to protein family HMM PF04183; IucC family siderophore biosynthesis protein 117423 3236841 SACOL0102 Staphylococcus aureus subsp. aureus COL IucC family siderophore biosynthesis protein YP_185006.1 115669 D 93062 CDS YP_185007.1 57652466 3236842 117416..118672 1 NC_002951.2 identified by similarity to EGAD:9939; match to protein family HMM PF00083; match to protein family HMM PF07690; drug transporter 118672 3236842 SACOL0103 Staphylococcus aureus subsp. aureus COL drug transporter YP_185007.1 117416 D 93062 CDS YP_185008.1 57652467 3236843 118662..120398 1 NC_002951.2 identified by match to protein family HMM PF04183; IucA family siderophore biosynthesis protein 120398 3236843 SACOL0104 Staphylococcus aureus subsp. aureus COL IucA family siderophore biosynthesis protein YP_185008.1 118662 D 93062 CDS YP_185009.1 57652468 3236844 120379..122157 1 NC_002951.2 identified by match to protein family HMM PF04183; IucC family siderophore biosynthesis protein 122157 3236844 SACOL0105 Staphylococcus aureus subsp. aureus COL IucC family siderophore biosynthesis protein YP_185009.1 120379 D 93062 CDS YP_185010.1 57652469 3236845 122132..122908 1 NC_002951.2 identified by match to protein family HMM PF03328; HPCH/HPAI aldolase 122908 3236845 SACOL0106 Staphylococcus aureus subsp. aureus COL HPCH/HPAI aldolase YP_185010.1 122132 D 93062 CDS YP_185011.1 57652470 3236846 122908..124110 1 NC_002951.2 identified by match to protein family HMM PF00278; match to protein family HMM PF02784; pyridoxal-dependent decarboxylase 124110 3236846 SACOL0107 Staphylococcus aureus subsp. aureus COL pyridoxal-dependent decarboxylase YP_185011.1 122908 D 93062 CDS YP_185012.1 57652471 3236847 124114..124878 1 NC_002951.2 hypothetical protein 124878 3236847 SACOL0108 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185012.1 124114 D 93062 CDS YP_185013.1 57652472 3236832 125074..125481 1 NC_002951.2 hypothetical protein 125481 3236832 SACOL0109 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185013.1 125074 D 93062 CDS YP_185014.1 57652473 3236833 125531..126157 1 NC_002951.2 hypothetical protein 126157 3236833 SACOL0110 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185014.1 125531 D 93062 CDS YP_185015.1 57652474 3236834 126369..127145 1 NC_002951.2 identified by match to protein family HMM PF00106; acetoin reductase 127145 3236834 SACOL0111 Staphylococcus aureus subsp. aureus COL acetoin reductase YP_185015.1 126369 D 93062 CDS YP_185016.1 57652475 3236835 127289..127411 1 NC_002951.2 hypothetical protein 127411 3236835 SACOL0112 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185016.1 127289 D 93062 CDS YP_185017.1 57652476 3236836 127490..128461 1 NC_002951.2 identified by match to protein family HMM PF01370; NAD-dependent epimerase/dehydratase 128461 3236836 SACOL0113 Staphylococcus aureus subsp. aureus COL NAD-dependent epimerase/dehydratase YP_185017.1 127490 D 93062 CDS YP_185018.1 57652477 3236837 128424..129116 1 NC_002951.2 identified by match to protein family HMM PF02397; capsular polysaccharide biosynthesis glycosyltransferase 129116 3236837 SACOL0114 Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis glycosyltransferase YP_185018.1 128424 D 93062 CDS YP_185019.1 57652478 3236838 129326..130492 1 NC_002951.2 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein 130492 3236838 SACOL0115 Staphylococcus aureus subsp. aureus COL glycosyl transferase, group 1 family protein YP_185019.1 129326 D 93062 CDS YP_185020.1 57652479 3236824 130473..131711 1 NC_002951.2 hypothetical protein 131711 3236824 SACOL0116 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185020.1 130473 D 93062 CDS YP_185021.1 57652480 3236825 131701..133131 1 NC_002951.2 identified by match to protein family HMM PF01943; polysaccharide extrusion protein 133131 3236825 SACOL0117 Staphylococcus aureus subsp. aureus COL polysaccharide extrusion protein YP_185021.1 131701 D 93062 CDS YP_185022.1 57652481 3236826 133399..133998 1 NC_002951.2 identified by similarity to SP:P54375; match to protein family HMM PF00081; match to protein family HMM PF02777; superoxide dismutase 133998 sodA1 3236826 sodA1 Staphylococcus aureus subsp. aureus COL superoxide dismutase YP_185022.1 133399 D 93062 CDS YP_185023.1 57652482 3236827 134366..135091 1 NC_002951.2 identified by match to protein family HMM PF00746; match to protein family HMM TIGR01167; cell wall surface anchor family protein 135091 3236827 SACOL0119 Staphylococcus aureus subsp. aureus COL cell wall surface anchor family protein YP_185023.1 134366 D 93062 CDS YP_185024.1 57652483 3236828 complement(135283..136038) 1 NC_002951.2 identified by similarity to EGAD:37606; match to protein family HMM PF00392; GntR family transcriptional regulator 136038 3236828 SACOL0120 Staphylococcus aureus subsp. aureus COL GntR family transcriptional regulator YP_185024.1 135283 R 93062 CDS YP_185025.1 57652484 3236829 136274..136981 1 NC_002951.2 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 136981 deoD1 3236829 deoD1 Staphylococcus aureus subsp. aureus COL purine nucleoside phosphorylase YP_185025.1 136274 D 93062 CDS YP_185026.1 57652485 3236830 136988..138340 1 NC_002951.2 identified by match to protein family HMM PF07690; tetracycline resistance protein 138340 3236830 SACOL0122 Staphylococcus aureus subsp. aureus COL tetracycline resistance protein YP_185026.1 136988 D 93062 CDS YP_185027.1 57651144 3236767 138421..139083 1 NC_002951.2 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 139083 deoC1 3236767 deoC1 Staphylococcus aureus subsp. aureus COL deoxyribose-phosphate aldolase YP_185027.1 138421 D 93062 CDS YP_185028.1 57651145 3236235 139111..140289 1 NC_002951.2 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 140289 deoB 3236235 deoB Staphylococcus aureus subsp. aureus COL phosphopentomutase YP_185028.1 139111 D 93062 CDS YP_185029.1 57651146 3236236 complement(140420..141235) 1 NC_002951.2 identified by similarity to SP:P16683; match to protein family HMM PF00528; match to protein family HMM TIGR01097; phosphonate ABC transporter permease 141235 3236236 SACOL0125 Staphylococcus aureus subsp. aureus COL phosphonate ABC transporter permease YP_185029.1 140420 R 93062 CDS YP_185030.1 57651147 3236237 complement(141232..142032) 1 NC_002951.2 identified by similarity to SP:P16683; match to protein family HMM PF00528; match to protein family HMM TIGR01097; phosphonate ABC transporter permease 142032 3236237 SACOL0126 Staphylococcus aureus subsp. aureus COL phosphonate ABC transporter permease YP_185030.1 141232 R 93062 CDS YP_185031.1 57651148 3236238 complement(142034..142807) 1 NC_002951.2 identified by similarity to EGAD:19702; match to protein family HMM PF00005; match to protein family HMM TIGR02315; phosphonate ABC transporter ATP-binding protein 142807 3236238 SACOL0127 Staphylococcus aureus subsp. aureus COL phosphonate ABC transporter ATP-binding protein YP_185031.1 142034 R 93062 CDS YP_185032.1 57651149 3236239 complement(143021..143977) 1 NC_002951.2 identified by similarity to EGAD:8376; match to protein family HMM TIGR01098; phosphonate ABC transporter phosphonate-binding protein 143977 3236239 SACOL0128 Staphylococcus aureus subsp. aureus COL phosphonate ABC transporter phosphonate-binding protein YP_185032.1 143021 R 93062 CDS YP_185033.1 57651150 3236069 144206..145750 1 NC_002951.2 identified by similarity to GB:AAO05899.1; hypothetical protein 145750 3236069 SACOL0129 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185033.1 144206 D 93062 CDS YP_185034.1 57651151 3236070 145801..147336 1 NC_002951.2 identified by match to protein family HMM PF00149; match to protein family HMM PF02872; 5' nucleotidase 147336 3236070 SACOL0130 Staphylococcus aureus subsp. aureus COL 5' nucleotidase YP_185034.1 145801 D 93062 CDS YP_185035.1 57651152 3236368 150451..153060 1 NC_002951.2 identified by similarity to SP:P17547; match to protein family HMM PF00465; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 153060 3236368 SACOL0135 Staphylococcus aureus subsp. aureus COL bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_185035.1 150451 D 93062 CDS YP_185036.1 57651153 3236369 153405..154073 1 NC_002951.2 identified by match to protein family HMM PF02706; match to protein family HMM TIGR01006; capsular polysaccharide biosynthesis protein Cap5A 154073 cap5A 3236369 cap5A Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis protein Cap5A YP_185036.1 153405 D 93062 CDS YP_185037.1 57651154 3236370 154089..154775 1 NC_002951.2 identified by match to protein family HMM TIGR01007; capsular polysaccharide biosynthesis protein Cap5B 154775 cap5B 3236370 cap5B Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis protein Cap5B YP_185037.1 154089 D 93062 CDS YP_185038.1 57651155 3236020 154778..155542 1 NC_002951.2 identified by match to protein family HMM PF02811; capsular polysaccharide biosynthesis protein Cap5C 155542 cap5C 3236020 cap5C Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis protein Cap5C YP_185038.1 154778 D 93062 CDS YP_185039.1 57651156 3236021 155562..157385 1 NC_002951.2 identified by match to protein family HMM PF02719; capsular polysaccharide biosynthesis protein Cap5D 157385 cap5D 3236021 cap5D Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis protein Cap5D YP_185039.1 155562 D 93062 CDS YP_185040.1 57651157 3236022 157375..158403 1 NC_002951.2 identified by match to protein family HMM PF02719; capsular polysaccharide biosynthesis protein Cap5E 158403 cap5E 3236022 cap5E Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis protein Cap5E YP_185040.1 157375 D 93062 CDS YP_185041.1 57651158 3236023 158416..159525 1 NC_002951.2 capsular polysaccharide biosynthesis protein Cap5F 159525 cap5F 3236023 cap5F Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis protein Cap5F YP_185041.1 158416 D 93062 CDS YP_185042.1 57651159 3236620 159529..160653 1 NC_002951.2 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236; UDP-N-acetylglucosamine 2-epimerase Cap5G 160653 cap5G 3236620 cap5G Staphylococcus aureus subsp. aureus COL UDP-N-acetylglucosamine 2-epimerase Cap5G YP_185042.1 159529 D 93062 CDS YP_185043.1 57651160 3236621 160656..161282 1 NC_002951.2 identified by match to protein family HMM PF00132; capsular polysaccharide biosynthesis protein Cap5H 161282 cap5H 3236621 cap5H Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis protein Cap5H YP_185043.1 160656 D 93062 CDS YP_185044.1 57651161 3236622 161287..162396 1 NC_002951.2 capsular polysaccharide biosynthesis protein Cap5I 162396 cap5I 3236622 cap5I Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis protein Cap5I YP_185044.1 161287 D 93062 CDS YP_185045.1 57651162 3236731 162410..163576 1 NC_002951.2 identified by match to protein family HMM PF04932; capsular polysaccharide biosynthesis protein Cap5J 163576 cap5J 3236731 cap5J Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis protein Cap5J YP_185045.1 162410 D 93062 CDS YP_185046.1 57651163 3236732 163569..164774 1 NC_002951.2 capsular polysaccharide biosynthesis protein Cap5K 164774 cap5K 3236732 cap5K Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis protein Cap5K YP_185046.1 163569 D 93062 CDS YP_185047.1 57651164 3236733 164775..165980 1 NC_002951.2 identified by match to protein family HMM PF00534; capsular polysaccharide biosynthesis protein Cap5L 165980 cap5L 3236733 cap5L Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis protein Cap5L YP_185047.1 164775 D 93062 CDS YP_185048.1 57651165 3236734 165991..166548 1 NC_002951.2 identified by match to protein family HMM PF02397; capsular polysaccharide biosynthesis galactosyltransferase Cap5M 166548 cap5M 3236734 cap5M Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis galactosyltransferase Cap5M YP_185048.1 165991 D 93062 CDS YP_185049.1 57651166 3237869 166548..167435 1 NC_002951.2 capsular polysaccharide biosynthesis protein Cap5N 167435 cap5N 3237869 cap5N Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis protein Cap5N YP_185049.1 166548 D 93062 CDS YP_185050.1 57651167 3237870 167489..168751 1 NC_002951.2 identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; capsular polysaccharide biosynthesis protein Cap5O 168751 cap5O 3237870 cap5O Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis protein Cap5O YP_185050.1 167489 D 93062 CDS YP_185051.1 57651168 3237871 168798..169973 1 NC_002951.2 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236; UDP-N-acetylglucosamine 2-epimerase Cap5P 169973 cap5P 3237871 cap5P Staphylococcus aureus subsp. aureus COL UDP-N-acetylglucosamine 2-epimerase Cap5P YP_185051.1 168798 D 93062 CDS YP_185052.1 57651169 3237872 complement(170038..170364) 1 NC_002951.2 iron regulated; catalyzes the release of heme from hemoglobin allowing bacterial pathogens to use the host heme as an iron source; heme-degrading monooxygenase IsdI 170364 3237872 SACOL0152 Staphylococcus aureus subsp. aureus COL heme-degrading monooxygenase IsdI YP_185052.1 170038 R 93062 CDS YP_185053.1 57651170 3237873 complement(170371..170754) 1 NC_002951.2 identified by match to protein family HMM PF04304; hypothetical protein 170754 3237873 SACOL0153 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185053.1 170371 R 93062 CDS YP_185054.1 57651171 3238707 171181..172668 1 NC_002951.2 identified by similarity to EGAD:15875; match to protein family HMM PF00171; aldehyde dehydrogenase 172668 aldA1 3238707 aldA1 Staphylococcus aureus subsp. aureus COL aldehyde dehydrogenase YP_185054.1 171181 D 93062 CDS YP_185055.1 57651172 3238708 173314..174273 1 NC_002951.2 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux family protein 174273 3238708 SACOL0155 Staphylococcus aureus subsp. aureus COL cation efflux family protein YP_185055.1 173314 D 93062 CDS YP_185056.1 57651173 3238709 complement(174335..174538) 1 NC_002951.2 hypothetical protein 174538 3238709 SACOL0156 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185056.1 174335 R 93062 CDS YP_185057.1 57651174 3238710 174717..175229 1 NC_002951.2 hypothetical protein 175229 3238710 SACOL0157 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185057.1 174717 D 93062 CDS YP_185058.1 57651175 3237543 177296..178057 1 NC_002951.2 identified by match to protein family HMM PF00528; ABC transporter permease 178057 3237543 SACOL0159 Staphylococcus aureus subsp. aureus COL ABC transporter permease YP_185058.1 177296 D 93062 CDS YP_185059.1 57651176 3237544 178070..179101 1 NC_002951.2 identified by similarity to EGAD:175821; hypothetical protein 179101 3237544 SACOL0160 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185059.1 178070 D 93062 CDS YP_185060.1 57651177 3237545 179318..179677 1 NC_002951.2 hypothetical protein 179677 3237545 SACOL0161 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185060.1 179318 D 93062 CDS YP_185061.1 57651178 3237546 179850..180875 1 NC_002951.2 Catalyzes the reversible two-electron oxidation of formate to carbon dioxide. It allows the assimilation of carbon dioxide and provides energy for growth through oxidative phosphorylation coupled to the reduction of oxygen, nitrate, sulphate or fumarate; formate dehydrogenase 180875 3237546 SACOL0162 Staphylococcus aureus subsp. aureus COL formate dehydrogenase YP_185061.1 179850 D 93062 CDS YP_185062.1 57651179 3236418 181261..182511 1 NC_002951.2 identified by similarity to EGAD:9179; match to protein family HMM PF07690; drug transporter 182511 3236418 SACOL0163 Staphylococcus aureus subsp. aureus COL drug transporter YP_185062.1 181261 D 93062 CDS YP_185063.1 57651180 3236419 182958..190133 1 NC_002951.2 identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM TIGR01733; match to protein family HMM TIGR01746; gramicidin S synthetase 2 related protein 190133 3236419 SACOL0164 Staphylococcus aureus subsp. aureus COL gramicidin S synthetase 2 related protein YP_185063.1 182958 D 93062 CDS YP_185064.1 57651181 3236420 190146..190790 1 NC_002951.2 identified by match to protein family HMM PF01648; 4'-phosphopantetheinyl transferase 190790 3236420 SACOL0165 Staphylococcus aureus subsp. aureus COL 4'-phosphopantetheinyl transferase YP_185064.1 190146 D 93062 CDS YP_185065.1 57651182 3236421 complement(191118..191612) 1 NC_002951.2 identified by match to protein family HMM PF07274; hypothetical protein 191612 3236421 SACOL0166 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185065.1 191118 R 93062 CDS YP_185066.1 57651183 3236422 complement(191867..192631) 1 NC_002951.2 identified by similarity to EGAD:15079; match to protein family HMM PF00696; match to protein family HMM TIGR00761; acetylglutamate kinase 192631 argB 3236422 argB Staphylococcus aureus subsp. aureus COL acetylglutamate kinase YP_185066.1 191867 R 93062 CDS YP_185067.1 57651184 3236042 complement(192647..193888) 1 NC_002951.2 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 193888 argJ 3236042 argJ Staphylococcus aureus subsp. aureus COL bifunctional ornithine acetyltransferase/N-acetylglutamate synthase YP_185067.1 192647 R 93062 CDS YP_185068.1 57651185 3236043 complement(193900..194931) 1 NC_002951.2 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 194931 argC 3236043 argC Staphylococcus aureus subsp. aureus COL N-acetyl-gamma-glutamyl-phosphate reductase YP_185068.1 193900 R 93062 CDS YP_185069.1 57651186 3236044 complement(194970..196154) 1 NC_002951.2 identified by similarity to SP:P38021; match to protein family HMM PF00202; match to protein family HMM TIGR01885; ornithine aminotransferase 196154 rocD1 3236044 rocD1 Staphylococcus aureus subsp. aureus COL ornithine aminotransferase YP_185069.1 194970 R 93062 CDS YP_185070.1 57651187 3236045 complement(196407..197762) 1 NC_002951.2 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 197762 brnQ1 3236045 brnQ1 Staphylococcus aureus subsp. aureus COL branched-chain amino acid transport system II carrier protein YP_185070.1 196407 R 93062 CDS YP_185071.1 57651188 3236174 complement(198038..198535) 1 NC_002951.2 identified by similarity to GP:1736514; match to protein family HMM PF00857; isochorismatase 198535 entB 3236174 entB Staphylococcus aureus subsp. aureus COL isochorismatase YP_185071.1 198038 R 93062 CDS YP_185072.1 57651189 3236175 complement(198662..200302) 1 NC_002951.2 identified by similarity to EGAD:20234; match to protein family HMM PF00205; match to protein family HMM PF02776; indole-3-pyruvate decarboxylase 200302 ipdC 3236175 ipdC Staphylococcus aureus subsp. aureus COL indole-3-pyruvate decarboxylase YP_185072.1 198662 R 93062 CDS YP_185073.1 57651190 3236176 200496..200597 1 NC_002951.2 hypothetical protein 200597 3236176 SACOL0174 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185073.1 200496 D 93062 CDS YP_185074.1 57651191 3236177 complement(200576..202621) 1 NC_002951.2 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR02002; PTS system, IIABC components 202621 3236177 SACOL0175 Staphylococcus aureus subsp. aureus COL PTS system, IIABC components YP_185074.1 200576 R 93062 CDS YP_185075.1 57651192 3236178 203207..204262 1 NC_002951.2 identified by match to protein family HMM PF05913; hypothetical protein 204262 3236178 SACOL0176 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185075.1 203207 D 93062 CDS YP_185076.1 57651193 3236402 204259..205158 1 NC_002951.2 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 205158 murQ 3236402 murQ Staphylococcus aureus subsp. aureus COL N-acetylmuramic acid-6-phosphate etherase YP_185076.1 204259 D 93062 CDS YP_185077.1 57651194 3236403 205170..206624 1 NC_002951.2 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; PTS system, IIBC components 206624 3236403 SACOL0178 Staphylococcus aureus subsp. aureus COL PTS system, IIBC components YP_185077.1 205170 D 93062 CDS YP_185078.1 57651195 3236404 206627..207502 1 NC_002951.2 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; RpiR family phosphosugar-binding transcriptional regulator 207502 3236404 SACOL0179 Staphylococcus aureus subsp. aureus COL RpiR family phosphosugar-binding transcriptional regulator YP_185078.1 206627 D 93062 CDS YP_185079.1 57651196 3236405 208190..210979 1 NC_002951.2 identified by match to protein family HMM PF00270; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM TIGR00348; type I restriction-modification enzyme, R subunit 210979 3236405 SACOL0180 Staphylococcus aureus subsp. aureus COL type I restriction-modification enzyme, R subunit YP_185079.1 208190 D 93062 CDS YP_185080.1 57651197 3236406 211184..212026 1 NC_002951.2 hypothetical protein 212026 3236406 SACOL0181 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185080.1 211184 D 93062 CDS YP_185081.1 57651198 3236714 212028..212951 1 NC_002951.2 hypothetical protein 212951 3236714 SACOL0182 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185081.1 212028 D 93062 CDS YP_185082.1 57651199 3236715 212938..214050 1 NC_002951.2 hypothetical protein 214050 3236715 SACOL0183 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185082.1 212938 D 93062 CDS YP_185083.1 57651200 3236716 complement(214315..215907) 1 NC_002951.2 identified by match to protein family HMM PF00005; peptide ABC transporter ATP-binding protein 215907 3236716 SACOL0184 Staphylococcus aureus subsp. aureus COL peptide ABC transporter ATP-binding protein YP_185083.1 214315 R 93062 CDS YP_185084.1 57651201 3236717 216035..217342 1 NC_002951.2 identified by match to protein family HMM PF00528; peptide ABC transporter permease 217342 3236717 SACOL0185 Staphylococcus aureus subsp. aureus COL peptide ABC transporter permease YP_185084.1 216035 D 93062 CDS YP_185085.1 57651202 3236718 217348..218511 1 NC_002951.2 identified by match to protein family HMM PF00528; peptide ABC transporter permease 218511 3236718 SACOL0186 Staphylococcus aureus subsp. aureus COL peptide ABC transporter permease YP_185085.1 217348 D 93062 CDS YP_185086.1 57651203 3236719 218528..220303 1 NC_002951.2 RGD-containing lipoprotein 220303 3236719 SACOL0187 Staphylococcus aureus subsp. aureus COL RGD-containing lipoprotein YP_185086.1 218528 D 93062 CDS YP_185087.1 57651204 3236413 220341..222347 1 NC_002951.2 identified by similarity to EGAD:45768; match to protein family HMM PF01019; match to protein family HMM TIGR00066; gamma-glutamyltranspeptidase 222347 ggt 3236413 ggt Staphylococcus aureus subsp. aureus COL gamma-glutamyltranspeptidase YP_185087.1 220341 D 93062 CDS YP_185088.1 57651205 3236414 complement(222645..223418) 1 NC_002951.2 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742; hypothetical protein 223418 3236414 SACOL0189 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185088.1 222645 R 93062 CDS YP_185089.1 57651206 3236415 complement(223608..224234) 1 NC_002951.2 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase 224234 acpD 3236415 acpD Staphylococcus aureus subsp. aureus COL azoreductase YP_185089.1 223608 R 93062 CDS YP_185090.1 57651207 3236416 224443..225021 1 NC_002951.2 identified by match to protein family HMM PF01551; M23/M37 peptidase domain-containing protein 225021 3236416 SACOL0191 Staphylococcus aureus subsp. aureus COL M23/M37 peptidase domain-containing protein YP_185090.1 224443 D 93062 CDS YP_185091.1 57651208 3236417 225404..226501 1 NC_002951.2 identified by similarity to EGAD:108619; match to protein family HMM PF00005; match to protein family HMM PF03459; maltose ABC transporter ATP-binding protein 226501 3236417 SACOL0192 Staphylococcus aureus subsp. aureus COL maltose ABC transporter ATP-binding protein YP_185091.1 225404 D 93062 CDS YP_185092.1 57651209 3236253 226514..227785 1 NC_002951.2 identified by similarity to EGAD:7280; match to protein family HMM PF01547; maltose ABC transporter maltose-binding protein 227785 3236253 SACOL0193 Staphylococcus aureus subsp. aureus COL maltose ABC transporter maltose-binding protein YP_185092.1 226514 D 93062 CDS YP_185093.1 57651210 3236254 227788..229056 1 NC_002951.2 identified by similarity to EGAD:6251; match to protein family HMM PF00528; match to protein family HMM PF05154; maltose ABC transporter permease 229056 3236254 SACOL0194 Staphylococcus aureus subsp. aureus COL maltose ABC transporter permease YP_185093.1 227788 D 93062 CDS YP_185094.1 57651211 3236255 229058..229897 1 NC_002951.2 identified by match to protein family HMM PF00528; maltose ABC transporter permease 229897 3236255 SACOL0195 Staphylococcus aureus subsp. aureus COL maltose ABC transporter permease YP_185094.1 229058 D 93062 CDS YP_185095.1 57651212 3236256 229971..231047 1 NC_002951.2 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; Gfo/Idh/MocA family oxidoreductase 231047 3236256 SACOL0196 Staphylococcus aureus subsp. aureus COL Gfo/Idh/MocA family oxidoreductase YP_185095.1 229971 D 93062 CDS YP_185096.1 57651213 3236257 231072..232112 1 NC_002951.2 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; Gfo/Idh/MocA family oxidoreductase 232112 3236257 SACOL0197 Staphylococcus aureus subsp. aureus COL Gfo/Idh/MocA family oxidoreductase YP_185096.1 231072 D 93062 CDS YP_185097.1 57651214 3236768 232167..233135 1 NC_002951.2 identified by similarity to GP:10173865; match to protein family HMM PF07582; hypothetical protein 233135 3236768 SACOL0198 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185097.1 232167 D 93062 CDS YP_185098.1 57651215 3236769 complement(233496..234068) 1 NC_002951.2 identified by similarity to EGAD:28959; match to protein family HMM PF04140; hypothetical protein 234068 3236769 SACOL0199 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185098.1 233496 R 93062 CDS YP_185099.1 57651216 3236770 234223..235602 1 NC_002951.2 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 235602 uhpT 3236770 uhpT Staphylococcus aureus subsp. aureus COL sugar phosphate antiporter YP_185099.1 234223 D 93062 CDS YP_185100.1 57651217 3236771 complement(235961..236719) 1 NC_002951.2 identified by match to protein family HMM PF00072; match to protein family HMM PF00165; AraC family DNA-binding response regulator 236719 3236771 SACOL0201 Staphylococcus aureus subsp. aureus COL AraC family DNA-binding response regulator YP_185100.1 235961 R 93062 CDS YP_185101.1 57651218 3236772 complement(236712..238268) 1 NC_002951.2 identified by match to protein family HMM PF02518; match to protein family HMM PF06580; sensor histidine kinase 238268 3236772 SACOL0202 Staphylococcus aureus subsp. aureus COL sensor histidine kinase YP_185101.1 236712 R 93062 CDS YP_185102.1 57651219 3236773 complement(238265..239233) 1 NC_002951.2 iron compound ABC transporter iron compound-binding protein 239233 3236773 SACOL0203 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter iron compound-binding protein YP_185102.1 238265 R 93062 CDS YP_185103.1 57651220 3236774 239821..242070 1 NC_002951.2 identified by similarity to SP:P09373; match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255; formate acetyltransferase 242070 pflB 3236774 pflB Staphylococcus aureus subsp. aureus COL formate acetyltransferase YP_185103.1 239821 D 93062 CDS YP_185104.1 57651221 3236775 242093..242848 1 NC_002951.2 identified by similarity to SP:O68575; match to protein family HMM PF04055; pyruvate formate-lyase-activating enzyme 242848 pflA 3236775 pflA Staphylococcus aureus subsp. aureus COL pyruvate formate-lyase-activating enzyme YP_185104.1 242093 D 93062 CDS YP_185105.1 57651222 3236776 242952..243146 1 NC_002951.2 hypothetical protein 243146 3236776 SACOL0206 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185105.1 242952 D 93062 CDS YP_185106.1 57651223 3236777 243184..244947 1 NC_002951.2 identified by match to protein family HMM PF03009; hypothetical protein 244947 3236777 SACOL0207 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185106.1 243184 D 93062 CDS YP_185107.1 57652486 3236831 complement(245111..245455) 1 NC_002951.2 hypothetical protein 245455 3236831 SACOL0208 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185107.1 245111 R 93062 CDS YP_185108.1 57652487 3236816 245645..247555 1 NC_002951.2 identified by similarity to EGAD:7465; match to protein family HMM PF04022; staphylocoagulase precursor 247555 3236816 SACOL0209 Staphylococcus aureus subsp. aureus COL staphylocoagulase precursor YP_185108.1 245645 D 93062 CDS YP_185109.1 57652488 3236817 248021..248161 1 NC_002951.2 hypothetical protein 248161 3236817 SACOL0210 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185109.1 248021 D 93062 CDS YP_185110.1 57652489 3236818 complement(248158..249342) 1 NC_002951.2 identified by similarity to EGAD:174567; match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; acetyl-CoA acetyltransferase 249342 3236818 SACOL0211 Staphylococcus aureus subsp. aureus COL acetyl-CoA acetyltransferase YP_185110.1 248158 R 93062 CDS YP_185111.1 57652490 3236819 complement(249372..251633) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH3492; match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737; 3-hydroxyacyl-CoA dehydrogenase 251633 3236819 SACOL0212 Staphylococcus aureus subsp. aureus COL 3-hydroxyacyl-CoA dehydrogenase YP_185111.1 249372 R 93062 CDS YP_185112.1 57652491 3236820 complement(251819..253030) 1 NC_002951.2 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase 253030 3236820 SACOL0213 Staphylococcus aureus subsp. aureus COL acyl-CoA dehydrogenase YP_185112.1 251819 R 93062 CDS YP_185113.1 57652492 3236821 complement(253142..254647) 1 NC_002951.2 identified by similarity to EGAD:7530; match to protein family HMM PF00501; long-chain-fatty-acid--CoA ligase 254647 3236821 SACOL0214 Staphylococcus aureus subsp. aureus COL long-chain-fatty-acid--CoA ligase YP_185113.1 253142 R 93062 CDS YP_185114.1 57652493 3236822 complement(254673..256244) 1 NC_002951.2 identified by match to protein family HMM PF01144; propionate CoA-transferase 256244 3236822 SACOL0215 Staphylococcus aureus subsp. aureus COL propionate CoA-transferase YP_185114.1 254673 R 93062 CDS YP_185115.1 57652494 3236823 256691..257833 1 NC_002951.2 hypothetical protein 257833 3236823 SACOL0216 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185115.1 256691 D 93062 CDS YP_185116.1 57652495 3236809 complement(258147..259622) 1 NC_002951.2 identified by match to protein family HMM PF00496; ABC transporter substrate-binding protein 259622 3236809 SACOL0217 Staphylococcus aureus subsp. aureus COL ABC transporter substrate-binding protein YP_185116.1 258147 R 93062 CDS YP_185117.1 57652496 3236810 complement(259820..260176) 1 NC_002951.2 identified by similarity to SP:P76243; match to protein family HMM PF04343; hypothetical protein 260176 3236810 SACOL0218 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185117.1 259820 R 93062 CDS YP_185118.1 57652497 3236811 complement(260333..260506) 1 NC_002951.2 hypothetical protein 260506 3236811 SACOL0219 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185118.1 260333 R 93062 CDS YP_185119.1 57652498 3236812 complement(260532..261677) 1 NC_002951.2 identified by match to protein family HMM PF00042; match to protein family HMM PF00970; flavohemoprotein 261677 3236812 SACOL0220 Staphylococcus aureus subsp. aureus COL flavohemoprotein YP_185119.1 260532 R 93062 CDS YP_185120.1 57652499 3236813 262250..263203 1 NC_002951.2 identified by similarity to EGAD:7030; match to protein family HMM PF00056; match to protein family HMM PF02866; match to protein family HMM TIGR01771; L-lactate dehydrogenase 263203 ldh1 3236813 ldh1 Staphylococcus aureus subsp. aureus COL L-lactate dehydrogenase YP_185120.1 262250 D 93062 CDS YP_185121.1 57652500 3236814 complement(263371..263496) 1 NC_002951.2 hypothetical protein 263496 3236814 SACOL0223 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185121.1 263371 R 93062 CDS YP_185122.1 57652501 3236815 complement(263523..265052) 1 NC_002951.2 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; PTS system, IIBC components 265052 3236815 SACOL0224 Staphylococcus aureus subsp. aureus COL PTS system, IIBC components YP_185122.1 263523 R 93062 CDS YP_185123.1 57652502 3236710 265414..266349 1 NC_002951.2 identified by match to protein family HMM PF01156; inosine-uridine preferring nucleoside hydrolase 266349 3236710 SACOL0225 Staphylococcus aureus subsp. aureus COL inosine-uridine preferring nucleoside hydrolase YP_185123.1 265414 D 93062 CDS YP_185124.1 57652503 3236711 266688..268784 1 NC_002951.2 identified by match to protein family HMM PF00359; match to protein family HMM PF00874; BglG family transcriptional antiterminator 268784 3236711 SACOL0228 Staphylococcus aureus subsp. aureus COL BglG family transcriptional antiterminator YP_185124.1 266688 D 93062 CDS YP_185125.1 57652504 3236712 268769..269236 1 NC_002951.2 identified by match to protein family HMM PF00359; PTS system, sugar-specific IIA component 269236 3236712 SACOL0229 Staphylococcus aureus subsp. aureus COL PTS system, sugar-specific IIA component YP_185125.1 268769 D 93062 CDS YP_185126.1 57652505 3236713 269259..269537 1 NC_002951.2 identified by match to protein family HMM PF02302; PTS system, sorbitol-specific IIB component 269537 3236713 SACOL0230 Staphylococcus aureus subsp. aureus COL PTS system, sorbitol-specific IIB component YP_185126.1 269259 D 93062 CDS YP_185127.1 57652506 3236805 complement(269602..269736) 1 NC_002951.2 hypothetical protein 269736 3236805 SACOL0231 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185127.1 269602 R 93062 CDS YP_185128.1 57652507 3236806 269764..271023 1 NC_002951.2 identified by match to protein family HMM PF03611; match to protein family HMM TIGR00827; PTS system, sorbitol-specific IIC component 271023 3236806 SACOL0232 Staphylococcus aureus subsp. aureus COL PTS system, sorbitol-specific IIC component YP_185128.1 269764 D 93062 CDS YP_185129.1 57652508 3236807 271041..272096 1 NC_002951.2 identified by similarity to SP:Q06004; similarity to OMNI:NTL01BH0190; match to protein family HMM PF00107; sorbitol dehydrogenase 272096 gutB 3236807 gutB Staphylococcus aureus subsp. aureus COL sorbitol dehydrogenase YP_185129.1 271041 D 93062 CDS YP_185130.1 57652509 3236808 272098..272244 1 NC_002951.2 hypothetical protein 272244 3236808 SACOL0234 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185130.1 272098 D 93062 CDS YP_185131.1 57652510 3236701 272268..273311 1 NC_002951.2 identified by match to protein family HMM PF00107; hexitol dehydrogenase 273311 3236701 SACOL0235 Staphylococcus aureus subsp. aureus COL hexitol dehydrogenase YP_185131.1 272268 D 93062 CDS YP_185132.1 57652511 3236702 273839..274555 1 NC_002951.2 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 274555 ispD 3236702 ispD Staphylococcus aureus subsp. aureus COL 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_185132.1 273839 D 93062 CDS YP_185133.1 57652512 3236703 274548..275573 1 NC_002951.2 identified by match to protein family HMM PF00107; alcohol dehydrogenase, zinc-containing 275573 3236703 SACOL0237 Staphylococcus aureus subsp. aureus COL alcohol dehydrogenase, zinc-containing YP_185133.1 274548 D 93062 CDS YP_185134.1 57652513 3236704 275595..277289 1 NC_002951.2 identified by match to protein family HMM PF04464; teichoic acid biosynthesis protein 277289 3236704 SACOL0238 Staphylococcus aureus subsp. aureus COL teichoic acid biosynthesis protein YP_185134.1 275595 D 93062 CDS YP_185135.1 57652514 3236705 277717..278886 1 NC_002951.2 identified by match to protein family HMM PF04464; TagF domain-containing protein 278886 3236705 SACOL0239 Staphylococcus aureus subsp. aureus COL TagF domain-containing protein YP_185135.1 277717 D 93062 CDS YP_185136.1 57652515 3236706 279162..279878 1 NC_002951.2 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 279878 ispD 3236706 ispD Staphylococcus aureus subsp. aureus COL 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_185136.1 279162 D 93062 CDS YP_185137.1 57652516 3236707 279871..280896 1 NC_002951.2 identified by match to protein family HMM PF00107; alcohol dehydrogenase, zinc-containing 280896 3236707 SACOL0241 Staphylococcus aureus subsp. aureus COL alcohol dehydrogenase, zinc-containing YP_185137.1 279871 D 93062 CDS YP_185138.1 57652517 3236708 280918..282606 1 NC_002951.2 identified by match to protein family HMM PF04464; teichoic acid biosynthesis protein 282606 3236708 SACOL0242 Staphylococcus aureus subsp. aureus COL teichoic acid biosynthesis protein YP_185138.1 280918 D 93062 CDS YP_185139.1 57652518 3236695 282642..284363 1 NC_002951.2 identified by match to protein family HMM PF00535; glycosyl transferase, group 2 family protein 284363 3236695 SACOL0243 Staphylococcus aureus subsp. aureus COL glycosyl transferase, group 2 family protein YP_185139.1 282642 D 93062 CDS YP_185140.1 57652519 3236696 284503..285177 1 NC_002951.2 involved in peptidoglycan cross-linking; cell wall biosynthesis protein ScdA 285177 scdA 3236696 scdA Staphylococcus aureus subsp. aureus COL cell wall biosynthesis protein ScdA YP_185140.1 284503 D 93062 CDS YP_185141.1 57652520 3236697 285424..287178 1 NC_002951.2 identified by similarity to EGAD:42940; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694; sensor histidine kinase LytS 287178 lytS 3236697 lytS Staphylococcus aureus subsp. aureus COL sensor histidine kinase LytS YP_185141.1 285424 D 93062 CDS YP_185142.1 57652521 3236698 287181..287921 1 NC_002951.2 identified by similarity to EGAD:42941; match to protein family HMM PF00072; match to protein family HMM PF04397; two-component response regulator 287921 lytR 3236698 lytR Staphylococcus aureus subsp. aureus COL two-component response regulator YP_185142.1 287181 D 93062 CDS YP_185143.1 57652522 3236699 288034..288477 1 NC_002951.2 negatively regulates murein hydrolase activity; murein hydrolase regulator LrgA 288477 lrgA 3236699 lrgA Staphylococcus aureus subsp. aureus COL murein hydrolase regulator LrgA YP_185143.1 288034 D 93062 CDS YP_185144.1 57652523 3236700 288470..289171 1 NC_002951.2 in conjunction with LrgA this protein inhibits the expression or activity of extracellular murein hydrolases; antiholin-like protein LrgB 289171 lrgB 3236700 lrgB Staphylococcus aureus subsp. aureus COL antiholin-like protein LrgB YP_185144.1 288470 D 93062 CDS YP_185145.1 57652524 3236684 complement(289279..289983) 1 NC_002951.2 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 289983 3236684 SACOL0249 Staphylococcus aureus subsp. aureus COL GntR family transcriptional regulator YP_185145.1 289279 R 93062 CDS YP_185146.1 57652525 3236685 290132..290923 1 NC_002951.2 identified by match to protein family HMM PF00358; match to protein family HMM TIGR00830; PTS system, IIA component 290923 3236685 SACOL0250 Staphylococcus aureus subsp. aureus COL PTS system, IIA component YP_185146.1 290132 D 93062 CDS YP_185147.1 57652526 3236686 290939..292375 1 NC_002951.2 identified by similarity to EGAD:36677; match to protein family HMM PF00232; 6-phospho-beta-glucosidase 292375 bglA 3236686 bglA Staphylococcus aureus subsp. aureus COL 6-phospho-beta-glucosidase YP_185147.1 290939 D 93062 CDS YP_185148.1 57652527 3236687 complement(292809..293570) 1 NC_002951.2 hypothetical protein 293570 3236687 SACOL0252 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185148.1 292809 R 93062 CDS YP_185149.1 57652528 3236688 complement(293821..294735) 1 NC_002951.2 identified by similarity to EGAD:29131; match to protein family HMM PF00294; match to protein family HMM TIGR02152; ribokinase 294735 rbsK 3236688 rbsK Staphylococcus aureus subsp. aureus COL ribokinase YP_185149.1 293821 R 93062 CDS YP_185150.1 57652529 3236689 complement(294763..295167) 1 NC_002951.2 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 295167 3236689 SACOL0254 Staphylococcus aureus subsp. aureus COL D-ribose pyranase YP_185150.1 294763 R 93062 CDS YP_185151.1 57652530 3236690 complement(295182..296063) 1 NC_002951.2 identified by match to protein family HMM PF06800; hypothetical protein 296063 3236690 SACOL0255 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185151.1 295182 R 93062 CDS YP_185152.1 57652531 3236691 complement(296295..297293) 1 NC_002951.2 identified by similarity to SP:P25551; match to protein family HMM PF00356; match to protein family HMM PF00532; ribose operon repressor 297293 3236691 SACOL0257 Staphylococcus aureus subsp. aureus COL ribose operon repressor YP_185152.1 296295 R 93062 CDS YP_185153.1 57652532 3236677 297444..297623 1 NC_002951.2 hypothetical protein 297623 3236677 SACOL0258 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185153.1 297444 D 93062 CDS YP_185154.1 57652533 3236678 297673..298065 1 NC_002951.2 hypothetical protein 298065 3236678 SACOL0259 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185154.1 297673 D 93062 CDS YP_185156.1 57652535 3236680 complement(298738..300114) 1 NC_002951.2 identified by match to protein family HMM PF07690; drug transporter 300114 3236680 SACOL0261 Staphylococcus aureus subsp. aureus COL drug transporter YP_185156.1 298738 R 93062 CDS YP_185157.1 57652536 3236681 300348..301340 1 NC_002951.2 identified by similarity to EGAD:17563; match to protein family HMM PF02275; choloylglycine hydrolase 301340 3236681 SACOL0262 Staphylococcus aureus subsp. aureus COL choloylglycine hydrolase YP_185157.1 300348 D 93062 CDS YP_185158.1 57652537 3236682 301648..302616 1 NC_002951.2 identified by similarity to GP:2239274; match to protein family HMM PF01551; peptidoglycan hydrolase 302616 lytM 3236682 lytM Staphylococcus aureus subsp. aureus COL peptidoglycan hydrolase YP_185158.1 301648 D 93062 CDS YP_185159.1 57652538 3236683 complement(302668..303327) 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 303327 3236683 SACOL0264 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_185159.1 302668 R 93062 CDS YP_185160.1 57652539 3236669 complement(303341..304261) 1 NC_002951.2 hypothetical protein 304261 3236669 SACOL0265 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185160.1 303341 R 93062 CDS YP_185161.1 57652540 3236670 complement(304258..305424) 1 NC_002951.2 hypothetical protein 305424 3236670 SACOL0266 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185161.1 304258 R 93062 CDS YP_185162.1 57652541 3236671 complement(305492..307015) 1 NC_002951.2 hypothetical protein 307015 3236671 SACOL0267 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185162.1 305492 R 93062 CDS YP_185163.1 57652542 3236672 307286..307939 1 NC_002951.2 hypothetical protein 307939 3236672 SACOL0268 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185163.1 307286 D 93062 CDS YP_185164.1 57652543 3236673 307973..308560 1 NC_002951.2 hypothetical protein 308560 3236673 SACOL0269 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185164.1 307973 D 93062 CDS YP_185165.1 57652544 3236674 complement(308703..309596) 1 NC_002951.2 identified by match to protein family HMM PF05257; staphyloxanthin biosynthesis protein 309596 3236674 SACOL0270 Staphylococcus aureus subsp. aureus COL staphyloxanthin biosynthesis protein YP_185165.1 308703 R 93062 CDS YP_185166.1 57652545 3236675 309844..310137 1 NC_002951.2 identified by match to protein family HMM PF06013; hypothetical protein 310137 3236675 SACOL0271 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185166.1 309844 D 93062 CDS YP_185167.1 57652546 3236676 310221..313250 1 NC_002951.2 hypothetical protein 313250 3236676 SACOL0272 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185167.1 310221 D 93062 CDS YP_185168.1 57652547 3236661 313250..313708 1 NC_002951.2 hypothetical protein 313708 3236661 SACOL0273 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185168.1 313250 D 93062 CDS YP_185169.1 57652548 3236662 313680..313922 1 NC_002951.2 hypothetical protein 313922 3236662 SACOL0274 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185169.1 313680 D 93062 CDS YP_185170.1 57652549 3236663 313935..315269 1 NC_002951.2 hypothetical protein 315269 3236663 SACOL0275 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185170.1 313935 D 93062 CDS YP_185171.1 57652550 3236664 315291..319730 1 NC_002951.2 identified by similarity to EGAD:128572; match to protein family HMM PF01580; diarrheal toxin 319730 yukA 3236664 yukA Staphylococcus aureus subsp. aureus COL diarrheal toxin YP_185171.1 315291 D 93062 CDS YP_185172.1 57652551 3236665 319760..320152 1 NC_002951.2 hypothetical protein 320152 3236665 SACOL0277 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185172.1 319760 D 93062 CDS YP_185173.1 57652552 3236666 320168..320482 1 NC_002951.2 hypothetical protein 320482 3236666 SACOL0278 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185173.1 320168 D 93062 CDS YP_185174.1 57652553 3236667 320482..321156 1 NC_002951.2 hypothetical protein 321156 3236667 SACOL0279 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185174.1 320482 D 93062 CDS YP_185175.1 57652554 3236668 321156..321473 1 NC_002951.2 hypothetical protein 321473 3236668 SACOL0280 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185175.1 321156 D 93062 CDS YP_185176.1 57652555 3236653 321483..323327 1 NC_002951.2 hypothetical protein 323327 3236653 SACOL0281 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185176.1 321483 D 93062 CDS YP_185177.1 57652556 3236654 323338..323829 1 NC_002951.2 identified by match to protein family HMM PF04634; match to protein family HMM TIGR01741; hypothetical protein 323829 3236654 SACOL0282 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185177.1 323338 D 93062 CDS YP_185178.1 57652557 3236655 324037..324720 1 NC_002951.2 hypothetical protein 324720 3236655 SACOL0283 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185178.1 324037 D 93062 CDS YP_185179.1 57652558 3236656 324867..325478 1 NC_002951.2 hypothetical protein 325478 3236656 SACOL0284 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185179.1 324867 D 93062 CDS YP_185180.1 57652559 3236657 325614..325832 1 NC_002951.2 hypothetical protein 325832 3236657 SACOL0285 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185180.1 325614 D 93062 CDS YP_185181.1 57652560 3236658 325964..326464 1 NC_002951.2 identified by match to protein family HMM PF04634; match to protein family HMM TIGR01741; hypothetical protein 326464 3236658 SACOL0286 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185181.1 325964 D 93062 CDS YP_185182.2 228943814 3236659 326475..326975 1 NC_002951.2 identified by match to protein family HMM PF04634; match to protein family HMM TIGR01741; hypothetical protein 326975 3236659 SACOL0287 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185182.2 326475 D 93062 CDS YP_185183.1 57652562 3236646 327492..327983 1 NC_002951.2 identified by match to protein family HMM PF04634; match to protein family HMM TIGR01741; hypothetical protein 327983 3236646 SACOL0289 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185183.1 327492 D 93062 CDS YP_185184.1 57652563 3236647 328193..328876 1 NC_002951.2 hypothetical protein 328876 3236647 SACOL0290 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185184.1 328193 D 93062 CDS YP_185185.1 57652564 3236648 329462..329962 1 NC_002951.2 identified by match to protein family HMM PF04634; match to protein family HMM TIGR01741; hypothetical protein 329962 3236648 SACOL0291 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185185.1 329462 D 93062 CDS YP_185186.1 57652565 3236649 329974..330474 1 NC_002951.2 identified by match to protein family HMM PF04634; match to protein family HMM TIGR01741; hypothetical protein 330474 3236649 SACOL0292 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185186.1 329974 D 93062 CDS YP_185187.1 57652566 3236650 330485..330985 1 NC_002951.2 identified by match to protein family HMM PF04634; match to protein family HMM TIGR01741; hypothetical protein 330985 3236650 SACOL0293 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185187.1 330485 D 93062 CDS YP_185188.2 228943813 3236651 330996..331496 1 NC_002951.2 identified by match to protein family HMM PF04634; match to protein family HMM TIGR01741; hypothetical protein 331496 3236651 SACOL0294 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185188.2 330996 D 93062 CDS YP_185189.1 57651224 3236783 331507..332007 1 NC_002951.2 identified by match to protein family HMM PF04634; match to protein family HMM TIGR01741; hypothetical protein 332007 3236783 SACOL0295 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185189.1 331507 D 93062 CDS YP_185190.1 57651225 3236784 332018..332518 1 NC_002951.2 identified by match to protein family HMM PF04634; match to protein family HMM TIGR01741; hypothetical protein 332518 3236784 SACOL0296 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185190.1 332018 D 93062 CDS YP_185191.1 57651226 3236785 332529..333017 1 NC_002951.2 identified by match to protein family HMM PF04634; match to protein family HMM TIGR01741; hypothetical protein 333017 3236785 SACOL0297 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185191.1 332529 D 93062 CDS YP_185192.1 57651227 3236786 333640..334014 1 NC_002951.2 hypothetical protein 334014 3236786 SACOL0299 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185192.1 333640 D 93062 CDS YP_185193.1 57651228 3236787 334167..334565 1 NC_002951.2 hypothetical protein 334565 3236787 SACOL0300 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185193.1 334167 D 93062 CDS YP_185194.1 57651229 3236788 complement(334781..335626) 1 NC_002951.2 identified by match to protein family HMM PF01226; formate/nitrite transporter family protein 335626 3236788 SACOL0301 Staphylococcus aureus subsp. aureus COL formate/nitrite transporter family protein YP_185194.1 334781 R 93062 CDS YP_185195.1 57651230 3236948 complement(335842..337149) 1 NC_002951.2 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 337149 brnQ2 3236948 brnQ2 Staphylococcus aureus subsp. aureus COL branched-chain amino acid transport system II carrier protein YP_185195.1 335842 R 93062 CDS YP_185196.1 57651231 3236949 337733..338623 1 NC_002951.2 identified by match to protein family HMM PF03767; match to protein family HMM TIGR01533; 5'-nucleotidase 338623 3236949 SACOL0303 Staphylococcus aureus subsp. aureus COL 5'-nucleotidase YP_185196.1 337733 D 93062 CDS YP_185197.1 57651232 3236950 338872..339921 1 NC_002951.2 identified by match to protein family HMM PF02687; ABC transporter permease 339921 3236950 SACOL0305 Staphylococcus aureus subsp. aureus COL ABC transporter permease YP_185197.1 338872 D 93062 CDS YP_185198.1 57651233 3236951 339934..340611 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 340611 3236951 SACOL0306 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_185198.1 339934 D 93062 CDS YP_185199.1 57651234 3236952 340819..341850 1 NC_002951.2 identified by similarity to EGAD:33437; perfringolysin O regulator protein 341850 pfoR 3236952 pfoR Staphylococcus aureus subsp. aureus COL perfringolysin O regulator protein YP_185199.1 340819 D 93062 CDS YP_185200.1 57651235 3236778 342193..343311 1 NC_002951.2 identified by match to protein family HMM PF00294; carbohydrate kinase 343311 3236778 SACOL0308 Staphylococcus aureus subsp. aureus COL carbohydrate kinase YP_185200.1 342193 D 93062 CDS YP_185201.1 57651236 3236779 343286..344209 1 NC_002951.2 identified by match to protein family HMM PF04227; hypothetical protein 344209 3236779 SACOL0309 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185201.1 343286 D 93062 CDS YP_185202.1 57651237 3236780 344220..345440 1 NC_002951.2 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; nucleoside permease NupC 345440 3236780 SACOL0310 Staphylococcus aureus subsp. aureus COL nucleoside permease NupC YP_185202.1 344220 D 93062 CDS YP_185203.1 57651238 3236781 complement(345545..347077) 1 NC_002951.2 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; sodium:solute symporter family protein 347077 3236781 SACOL0311 Staphylococcus aureus subsp. aureus COL sodium:solute symporter family protein YP_185203.1 345545 R 93062 CDS YP_185204.1 57651239 3236782 complement(347117..347998) 1 NC_002951.2 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 347998 nanA 3236782 nanA Staphylococcus aureus subsp. aureus COL N-acetylneuraminate lyase YP_185204.1 347117 R 93062 CDS YP_185205.1 57651240 3236927 348156..349016 1 NC_002951.2 identified by match to protein family HMM PF00480; ROK family protein 349016 3236927 SACOL0313 Staphylococcus aureus subsp. aureus COL ROK family protein YP_185205.1 348156 D 93062 CDS YP_185206.1 57651241 3236928 complement(349294..350094) 1 NC_002951.2 identified by similarity to EGAD:15022; match to protein family HMM PF01380; hypothetical protein 350094 3236928 SACOL0314 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185206.1 349294 R 93062 CDS YP_185207.1 57651242 3236929 350234..350902 1 NC_002951.2 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 350902 3236929 SACOL0315 Staphylococcus aureus subsp. aureus COL N-acetylmannosamine-6-phosphate 2-epimerase YP_185207.1 350234 D 93062 CDS YP_185208.1 57651243 3236930 complement(351029..352342) 1 NC_002951.2 identified by match to protein family HMM PF07670; hypothetical protein 352342 3236930 SACOL0316 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185208.1 351029 R 93062 CDS YP_185209.1 57651244 3236931 352760..354694 1 NC_002951.2 identified by similarity to EGAD:17843; match to protein family HMM PF04650; match to protein family HMM TIGR01168; lipase precursor, interruption-N 354694 3236931 SACOL0317 Staphylococcus aureus subsp. aureus COL lipase precursor, interruption-N YP_185209.1 352760 D 93062 CDS YP_185210.1 57651245 3236912 complement(354785..355990) 1 NC_002951.2 identified by similarity to EGAD:72831; match to protein family HMM PF00589; prophage L54a, integrase 355990 int 3236912 int Staphylococcus aureus subsp. aureus COL prophage L54a, integrase YP_185210.1 354785 R 93062 CDS YP_185211.1 57651246 3236913 complement(356184..356897) 1 NC_002951.2 hypothetical protein 356897 3236913 SACOL0319 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185211.1 356184 R 93062 CDS YP_185212.1 57651247 3236914 complement(356975..357202) 1 NC_002951.2 hypothetical protein 357202 3236914 SACOL0320 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185212.1 356975 R 93062 CDS YP_185213.1 57651248 3236915 complement(357357..358076) 1 NC_002951.2 identified by similarity to GP:3341939; match to protein family HMM PF00717; match to protein family HMM PF01381; prophage L54a, repressor protein 358076 3236915 SACOL0321 Staphylococcus aureus subsp. aureus COL prophage L54a, repressor protein YP_185213.1 357357 R 93062 CDS YP_185214.1 57651249 3236916 358218..358436 1 NC_002951.2 identified by similarity to GP:11127678; prophage L54a, Cro-like protein 358436 3236916 SACOL0322 Staphylococcus aureus subsp. aureus COL prophage L54a, Cro-like protein YP_185214.1 358218 D 93062 CDS YP_185215.1 57651250 3236937 358451..358759 1 NC_002951.2 hypothetical protein 358759 3236937 SACOL0323 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185215.1 358451 D 93062 CDS YP_185216.1 57651251 3236938 complement(358763..358915) 1 NC_002951.2 hypothetical protein 358915 3236938 SACOL0324 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185216.1 358763 R 93062 CDS YP_185217.1 57651252 3236939 358916..359707 1 NC_002951.2 identified by similarity to GP:8918756; match to protein family HMM PF02498; prophage L54a, antirepressor 359707 3236939 SACOL0325 Staphylococcus aureus subsp. aureus COL prophage L54a, antirepressor YP_185217.1 358916 D 93062 CDS YP_185218.1 57651253 3236940 359708..359932 1 NC_002951.2 hypothetical protein 359932 3236940 SACOL0326 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185218.1 359708 D 93062 CDS YP_185219.1 57651254 3236941 359972..360217 1 NC_002951.2 hypothetical protein 360217 3236941 SACOL0327 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185219.1 359972 D 93062 CDS YP_185220.1 57651255 3236942 complement(360186..360551) 1 NC_002951.2 hypothetical protein 360551 3236942 SACOL0328 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185220.1 360186 R 93062 CDS YP_185221.1 57651256 3236932 360605..360805 1 NC_002951.2 identified by similarity to OMNI:NTL01SA1873; hypothetical protein 360805 3236932 SACOL0329 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185221.1 360605 D 93062 CDS YP_185222.1 57651257 3236933 complement(360792..361172) 1 NC_002951.2 identified by similarity to OMNI:NTL01SA1872; hypothetical protein 361172 3236933 SACOL0330 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185222.1 360792 R 93062 CDS YP_185223.1 57651258 3236934 361220..361411 1 NC_002951.2 hypothetical protein 361411 3236934 SACOL0331 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185223.1 361220 D 93062 CDS YP_185224.1 57651259 3236935 complement(361389..361640) 1 NC_002951.2 identified by similarity to GP:5730267; hypothetical protein 361640 3236935 SACOL0332 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185224.1 361389 R 93062 CDS YP_185225.1 57651260 3236936 361695..361958 1 NC_002951.2 identified by similarity to GP:3341945; hypothetical protein 361958 3236936 SACOL0333 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185225.1 361695 D 93062 CDS YP_185226.1 57651261 3236896 361971..362132 1 NC_002951.2 identified by similarity to OMNI:NTL01SA1870; match to protein family HMM PF06900; hypothetical protein 362132 3236896 SACOL0334 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185226.1 361971 D 93062 CDS YP_185227.1 57651262 3236897 362222..362539 1 NC_002951.2 hypothetical protein 362539 3236897 SACOL0335 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185227.1 362222 D 93062 CDS YP_185228.1 57651263 3236898 362544..362804 1 NC_002951.2 identified by similarity to GP:3341947; match to protein family HMM PF06531; hypothetical protein 362804 3236898 SACOL0336 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185228.1 362544 D 93062 CDS YP_185229.1 57651264 3236899 362814..363035 1 NC_002951.2 hypothetical protein 363035 3236899 SACOL0337 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185229.1 362814 D 93062 CDS YP_185230.1 57651265 3236900 363028..363651 1 NC_002951.2 identified by similarity to GP:3282307; match to protein family HMM PF06378; hypothetical protein 363651 3236900 SACOL0338 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185230.1 363028 D 93062 CDS YP_185231.1 57651266 3236901 363651..364070 1 NC_002951.2 identified by similarity to EGAD:17778; match to protein family HMM PF00436; match to protein family HMM TIGR00621; prophage L54a, single-stranded DNA binding protein 364070 ssb1 3236901 ssb1 Staphylococcus aureus subsp. aureus COL prophage L54a, single-stranded DNA binding protein YP_185231.1 363651 D 93062 CDS YP_185232.1 57651267 3236902 364084..364779 1 NC_002951.2 identified by similarity to GP:8918766; match to protein family HMM PF06147; hypothetical protein 364779 3236902 SACOL0340 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185232.1 364084 D 93062 CDS YP_185233.1 57651268 3236903 364751..365551 1 NC_002951.2 identified by similarity to GP:8918767; match to protein family HMM TIGR01446; match to protein family HMM TIGR01714; hypothetical protein 365551 3236903 SACOL0341 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185233.1 364751 D 93062 CDS YP_185234.1 57651269 3236904 365551..365907 1 NC_002951.2 hypothetical protein 365907 3236904 SACOL0342 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185234.1 365551 D 93062 CDS YP_185235.1 57651270 3236905 365904..367145 1 NC_002951.2 identified by similarity to EGAD:21924; match to protein family HMM PF03796; prophage L54a, replicative DNA helicase 367145 3236905 SACOL0343 Staphylococcus aureus subsp. aureus COL prophage L54a, replicative DNA helicase YP_185235.1 365904 D 93062 CDS YP_185236.1 57651271 3236906 367142..367357 1 NC_002951.2 hypothetical protein 367357 3236906 SACOL0344 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185236.1 367142 D 93062 CDS YP_185237.1 57651272 3236907 367360..367581 1 NC_002951.2 hypothetical protein 367581 3236907 SACOL0345 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185237.1 367360 D 93062 CDS YP_185238.1 57651273 3236908 367591..368016 1 NC_002951.2 identified by match to protein family HMM PF05869; match to protein family HMM TIGR01712; prophage L54a, N-6-adenine-methyltransferase 368016 3236908 SACOL0346 Staphylococcus aureus subsp. aureus COL prophage L54a, N-6-adenine-methyltransferase YP_185238.1 367591 D 93062 CDS YP_185239.1 57651274 3236909 368013..368417 1 NC_002951.2 identified by similarity to GP:8918440; match to protein family HMM PF06356; hypothetical protein 368417 3236909 SACOL0347 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185239.1 368013 D 93062 CDS YP_185240.1 57651275 3236910 368422..368607 1 NC_002951.2 identified by similarity to GP:8918770; hypothetical protein 368607 3236910 SACOL0348 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185240.1 368422 D 93062 CDS YP_185241.1 57651276 3236911 368608..368865 1 NC_002951.2 identified by similarity to GP:8918771; match to protein family HMM PF01381; hypothetical protein 368865 3236911 SACOL0349 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185241.1 368608 D 93062 CDS YP_185242.1 57651277 3236943 368877..369233 1 NC_002951.2 identified by similarity to GP:12697847; hypothetical protein 369233 3236943 SACOL0350 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185242.1 368877 D 93062 CDS YP_185243.1 57651278 3236944 369237..369479 1 NC_002951.2 identified by similarity to GP:12697848; match to protein family HMM PF06194; hypothetical protein 369479 3236944 SACOL0351 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185243.1 369237 D 93062 CDS YP_185244.1 57651279 3236945 369493..369699 1 NC_002951.2 hypothetical protein 369699 3236945 SACOL0352 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185244.1 369493 D 93062 CDS YP_185245.1 57651280 3236946 369702..370103 1 NC_002951.2 hypothetical protein 370103 3236946 SACOL0353 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185245.1 369702 D 93062 CDS YP_185246.1 57651281 3236947 370100..370447 1 NC_002951.2 identified by similarity to GP:5001708; match to protein family HMM TIGR01671; hypothetical protein 370447 3236947 SACOL0354 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185246.1 370100 D 93062 CDS YP_185247.1 57651282 3236922 370444..370752 1 NC_002951.2 identified by similarity to GP:8918774; hypothetical protein 370752 3236922 SACOL0355 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185247.1 370444 D 93062 CDS YP_185248.1 57651283 3236923 370745..370981 1 NC_002951.2 identified by similarity to GP:8918447; match to protein family HMM PF06260; hypothetical protein 370981 3236923 SACOL0356 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185248.1 370745 D 93062 CDS YP_185249.1 57651284 3236924 370986..371528 1 NC_002951.2 identified by similarity to SP:P33316; match to protein family HMM PF00692; prophage L54a, deoxyuridine 5'-triphosphate nucleotidohydrolase 371528 dut 3236924 dut Staphylococcus aureus subsp. aureus COL prophage L54a, deoxyuridine 5'-triphosphate nucleotidohydrolase YP_185249.1 370986 D 93062 CDS YP_185250.1 57651285 3236925 371565..371771 1 NC_002951.2 identified by similarity to OMNI:NTL02SA0871; match to protein family HMM PF07129; hypothetical protein 371771 3236925 SACOL0358 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185250.1 371565 D 93062 CDS YP_185251.1 57651286 3236926 371768..371962 1 NC_002951.2 hypothetical protein 371962 3236926 SACOL0359 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185251.1 371768 D 93062 CDS YP_185252.1 57651287 3236917 371959..372162 1 NC_002951.2 hypothetical protein 372162 3236917 SACOL0360 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185252.1 371959 D 93062 CDS YP_185253.1 57651288 3236918 372155..372307 1 NC_002951.2 identified by similarity to GP:12697854; match to protein family HMM PF06116; hypothetical protein 372307 3236918 SACOL0361 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185253.1 372155 D 93062 CDS YP_185254.1 57651289 3236919 372375..372575 1 NC_002951.2 identified by similarity to GP:12697855; match to protein family HMM PF07438; hypothetical protein 372575 3236919 SACOL0362 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185254.1 372375 D 93062 CDS YP_185255.1 57651290 3236920 372532..372882 1 NC_002951.2 identified by similarity to OMNI:SA0363; hypothetical protein 372882 3236920 SACOL0363 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185255.1 372532 D 93062 CDS YP_185256.1 57651291 3236921 372895..373332 1 NC_002951.2 identified by match to protein family HMM TIGR01636; prophage L54a, RinA family transcriptional regulator 373332 3236921 SACOL0364 Staphylococcus aureus subsp. aureus COL prophage L54a, RinA family transcriptional regulator YP_185256.1 372895 D 93062 CDS YP_185257.1 57651292 3236794 373489..373803 1 NC_002951.2 identified by match to protein family HMM PF01844; prophage L54a, HNH endonuclease 373803 3236794 SACOL0365 Staphylococcus aureus subsp. aureus COL prophage L54a, HNH endonuclease YP_185257.1 373489 D 93062 CDS YP_185258.1 57651293 3236795 373932..374237 1 NC_002951.2 identified by match to protein family HMM PF05119; prophage L54a, terminase, small subunit 374237 3236795 SACOL0366 Staphylococcus aureus subsp. aureus COL prophage L54a, terminase, small subunit YP_185258.1 373932 D 93062 CDS YP_185259.1 57651294 3236796 374227..375918 1 NC_002951.2 identified by similarity to GP:12697860; match to protein family HMM PF03354; prophage L54a, terminase, large subunit 375918 3236796 SACOL0367 Staphylococcus aureus subsp. aureus COL prophage L54a, terminase, large subunit YP_185259.1 374227 D 93062 CDS YP_185260.1 57651295 3236797 375923..377161 1 NC_002951.2 identified by similarity to GP:4126611; match to protein family HMM PF04860; match to protein family HMM TIGR01537; prophage L54a, HK97 family portal protein 377161 3236797 SACOL0368 Staphylococcus aureus subsp. aureus COL prophage L54a, HK97 family portal protein YP_185260.1 375923 D 93062 CDS YP_185261.1 57651296 3236798 377145..377918 1 NC_002951.2 identified by match to protein family HMM PF00574; prophage L54a, Clp protease 377918 3236798 SACOL0369 Staphylococcus aureus subsp. aureus COL prophage L54a, Clp protease YP_185261.1 377145 D 93062 CDS YP_185262.1 57651297 3236799 377930..379093 1 NC_002951.2 identified by match to protein family HMM PF05065; prophage L54a, major capsid protein 379093 3236799 SACOL0370 Staphylococcus aureus subsp. aureus COL prophage L54a, major capsid protein YP_185262.1 377930 D 93062 CDS YP_185263.1 57651298 3236800 379162..379440 1 NC_002951.2 identified by similarity to GP:13361058; match to protein family HMM TIGR01560; prophage L54a, DNA packaging protein 379440 3236800 SACOL0371 Staphylococcus aureus subsp. aureus COL prophage L54a, DNA packaging protein YP_185263.1 379162 D 93062 CDS YP_185264.1 57651299 3236801 379452..379784 1 NC_002951.2 hypothetical protein 379784 3236801 SACOL0372 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185264.1 379452 D 93062 CDS YP_185265.1 57651300 3236802 379781..380182 1 NC_002951.2 identified by similarity to GP:12697866; hypothetical protein 380182 3236802 SACOL0373 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185265.1 379781 D 93062 CDS YP_185266.1 57651301 3236803 380183..380578 1 NC_002951.2 identified by similarity to OMNI:NTL01SA1839; hypothetical protein 380578 3236803 SACOL0374 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185266.1 380183 D 93062 CDS YP_185267.1 57651302 3236804 380613..381254 1 NC_002951.2 identified by similarity to GP:12697868; match to protein family HMM PF04630; match to protein family HMM TIGR01603; prophage L54a, major tail protein 381254 3236804 SACOL0375 Staphylococcus aureus subsp. aureus COL prophage L54a, major tail protein YP_185267.1 380613 D 93062 CDS YP_185268.1 57651303 3236789 381346..381801 1 NC_002951.2 identified by match to protein family HMM PF02368; prophage L54a, major tail protein 381801 3236789 SACOL0376 Staphylococcus aureus subsp. aureus COL prophage L54a, major tail protein YP_185268.1 381346 D 93062 CDS YP_185269.1 57651304 3236790 381859..382209 1 NC_002951.2 hypothetical protein 382209 3236790 SACOL0377 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185269.1 381859 D 93062 CDS YP_185270.1 57651305 3236791 382251..382409 1 NC_002951.2 hypothetical protein 382409 3236791 SACOL0378 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185270.1 382251 D 93062 CDS YP_185271.1 57652568 3236652 382423..388623 1 NC_002951.2 identified by match to protein family HMM PF01551; match to protein family HMM TIGR01760; prophage L54a, TP901 family tail tape meausure protein 388623 3236652 SACOL0379 Staphylococcus aureus subsp. aureus COL prophage L54a, TP901 family tail tape meausure protein YP_185271.1 382423 D 93062 CDS YP_185272.1 57652569 3236638 388623..389447 1 NC_002951.2 identified by similarity to GP:12697873; match to protein family HMM PF06997; hypothetical protein 389447 3236638 SACOL0380 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185272.1 388623 D 93062 CDS YP_185273.1 57652570 3236639 389456..391039 1 NC_002951.2 identified by similarity to GP:12697874; match to protein family HMM PF06605; hypothetical protein 391039 3236639 SACOL0381 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185273.1 389456 D 93062 CDS YP_185274.1 57652571 3236640 391039..391329 1 NC_002951.2 hypothetical protein 391329 3236640 SACOL0382 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185274.1 391039 D 93062 CDS YP_185275.1 57652572 3236641 391345..393255 1 NC_002951.2 identified by similarity to GP:8918471; hypothetical protein 393255 3236641 SACOL0383 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185275.1 391345 D 93062 CDS YP_185276.1 57652573 3236642 393255..394721 1 NC_002951.2 identified by similarity to GP:8918472; hypothetical protein 394721 3236642 SACOL0384 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185276.1 393255 D 93062 CDS YP_185277.1 57652574 3236643 394721..395110 1 NC_002951.2 identified by similarity to GP:12697878; hypothetical protein 395110 3236643 SACOL0385 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185277.1 394721 D 93062 CDS YP_185278.1 57652575 3236644 395103..395267 1 NC_002951.2 identified by match to protein family HMM TIGR01669; hypothetical protein 395267 3236644 SACOL0386 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185278.1 395103 D 93062 CDS YP_185279.1 57652576 3236645 395313..395612 1 NC_002951.2 identified by similarity to GP:8918803; hypothetical protein 395612 3236645 SACOL0387 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185279.1 395313 D 93062 CDS YP_185280.1 57652577 3236631 395748..396050 1 NC_002951.2 identified by similarity to GP:3341931; match to protein family HMM PF04688; match to protein family HMM TIGR01592; prophage L54a, holin 396050 3236631 SACOL0388 Staphylococcus aureus subsp. aureus COL prophage L54a, holin YP_185280.1 395748 D 93062 CDS YP_185281.1 57652578 3236632 396062..397516 1 NC_002951.2 identified by similarity to GP:12697881; match to protein family HMM PF01520; match to protein family HMM PF05257; prophage L54a, amidase 397516 3236632 SACOL0389 Staphylococcus aureus subsp. aureus COL prophage L54a, amidase YP_185281.1 396062 D 93062 CDS YP_185282.1 57652579 3236633 398286..398408 1 NC_002951.2 identified by similarity to EGAD:17843; lipase precursor, interruption-C 398408 3236633 SACOL0390 Staphylococcus aureus subsp. aureus COL lipase precursor, interruption-C YP_185282.1 398286 D 93062 CDS YP_185283.1 57652580 3236634 complement(398650..399477) 1 NC_002951.2 hypothetical protein 399477 3236634 SACOL0391 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185283.1 398650 R 93062 CDS YP_185284.1 57652581 3236635 complement(399550..400749) 1 NC_002951.2 identified by match to protein family HMM PF00724; Oye family NADH-dependent flavin oxidoreductase 400749 3236635 SACOL0392 Staphylococcus aureus subsp. aureus COL Oye family NADH-dependent flavin oxidoreductase YP_185284.1 399550 R 93062 CDS YP_185285.1 57652582 3236636 400845..400937 1 NC_002951.2 hypothetical protein 400937 3236636 SACOL0393 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185285.1 400845 D 93062 CDS YP_185286.1 57652583 3236637 401051..402052 1 NC_002951.2 identified by match to protein family HMM PF00296; hypothetical protein 402052 3236637 SACOL0394 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185286.1 401051 D 93062 CDS YP_185287.1 57652584 3236623 402086..402418 1 NC_002951.2 identified by match to protein family HMM PF01597; glycine cleavage system H protein 402418 3236623 SACOL0395 Staphylococcus aureus subsp. aureus COL glycine cleavage system H protein YP_185287.1 402086 D 93062 CDS YP_185288.1 57652585 3236624 402419..403219 1 NC_002951.2 identified by match to protein family HMM PF01661; hypothetical protein 403219 3236624 SACOL0396 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185288.1 402419 D 93062 CDS YP_185289.1 57652586 3236625 403209..404153 1 NC_002951.2 hypothetical protein 404153 3236625 SACOL0397 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185289.1 403209 D 93062 CDS YP_185290.1 57652587 3236626 404131..405153 1 NC_002951.2 identified by match to protein family HMM PF03099; match to protein family HMM TIGR00545; lipoate-protein ligase A family protein 405153 3236626 SACOL0398 Staphylococcus aureus subsp. aureus COL lipoate-protein ligase A family protein YP_185290.1 404131 D 93062 CDS YP_185291.1 57652588 3236627 405468..406493 1 NC_002951.2 oxidoreductase 406493 3236627 SACOL0399 Staphylococcus aureus subsp. aureus COL oxidoreductase YP_185291.1 405468 D 93062 CDS YP_185292.1 57652589 3236628 complement(406586..407932) 1 NC_002951.2 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 407932 ulaA 3236628 ulaA Staphylococcus aureus subsp. aureus COL PTS system ascorbate-specific transporter subunit IIC YP_185292.1 406586 R 93062 CDS YP_185293.1 57652590 3236629 complement(407947..408231) 1 NC_002951.2 identified by match to protein family HMM PF02302; hypothetical protein 408231 3236629 SACOL0401 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185293.1 407947 R 93062 CDS YP_185294.1 57652591 3236630 complement(408233..408676) 1 NC_002951.2 identified by match to protein family HMM PF00359; PTS system, IIA component 408676 3236630 SACOL0402 Staphylococcus aureus subsp. aureus COL PTS system, IIA component YP_185294.1 408233 R 93062 CDS YP_185295.1 57652592 3236524 complement(408681..410636) 1 NC_002951.2 identified by match to protein family HMM PF00359; match to protein family HMM PF00874; BglG family transcriptional antiterminator 410636 3236524 SACOL0403 Staphylococcus aureus subsp. aureus COL BglG family transcriptional antiterminator YP_185295.1 408681 R 93062 CDS YP_185296.1 57652593 3236525 410848..411267 1 NC_002951.2 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 411267 3236525 SACOL0404 Staphylococcus aureus subsp. aureus COL MarR family transcriptional regulator YP_185296.1 410848 D 93062 CDS YP_185297.1 57652594 3236526 411374..412729 1 NC_002951.2 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797; MATE efflux family protein 412729 3236526 SACOL0405 Staphylococcus aureus subsp. aureus COL MATE efflux family protein YP_185297.1 411374 D 93062 CDS YP_185298.1 57652595 3236527 412833..413273 1 NC_002951.2 hypothetical protein 413273 3236527 SACOL0406 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185298.1 412833 D 93062 CDS YP_185299.1 57652596 3236528 complement(413356..414714) 1 NC_002951.2 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00712; match to protein family HMM TIGR00881; glycerol-3-phosphate transporter 414714 glpT 3236528 glpT Staphylococcus aureus subsp. aureus COL glycerol-3-phosphate transporter YP_185299.1 413356 R 93062 CDS YP_185300.1 57652597 3236529 415022..415882 1 NC_002951.2 identified by match to protein family HMM PF00903; glyoxalase 415882 3236529 SACOL0408 Staphylococcus aureus subsp. aureus COL glyoxalase YP_185300.1 415022 D 93062 CDS YP_185301.1 57652598 3236530 415962..417023 1 NC_002951.2 identified by similarity to GP:9965112; match to protein family HMM PF00296; hypothetical protein 417023 3236530 SACOL0409 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185301.1 415962 D 93062 CDS YP_185302.1 57652599 3236531 417037..417603 1 NC_002951.2 identified by match to protein family HMM PF03358; FMN reductase-like protein 417603 3236531 SACOL0410 Staphylococcus aureus subsp. aureus COL FMN reductase-like protein YP_185302.1 417037 D 93062 CDS YP_185303.1 57652600 3236516 complement(417663..418658) 1 NC_002951.2 identified by match to protein family HMM PF03601; hypothetical protein 418658 3236516 SACOL0411 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185303.1 417663 R 93062 CDS YP_185304.1 57652601 3236517 418756..419052 1 NC_002951.2 hypothetical protein 419052 3236517 SACOL0412 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185304.1 418756 D 93062 CDS YP_185305.1 57652602 3236518 419132..419677 1 NC_002951.2 identified by match to protein family HMM PF00583; ribosomal-protein-serine acetyltransferase 419677 3236518 SACOL0413 Staphylococcus aureus subsp. aureus COL ribosomal-protein-serine acetyltransferase YP_185305.1 419132 D 93062 CDS YP_185306.1 57652603 3236519 419945..420799 1 NC_002951.2 identified by match to protein family HMM PF04302; lipoprotein 420799 3236519 SACOL0414 Staphylococcus aureus subsp. aureus COL lipoprotein YP_185306.1 419945 D 93062 CDS YP_185307.1 57652604 3236520 420796..422025 1 NC_002951.2 identified by similarity to EGAD:20441; match to protein family HMM PF04261; match to protein family HMM TIGR01409; match to protein family HMM TIGR01412; match to protein family HMM TIGR01413; Dyp-type peroxidase 422025 3236520 SACOL0415 Staphylococcus aureus subsp. aureus COL Dyp-type peroxidase YP_185307.1 420796 D 93062 CDS YP_185308.1 57652605 3236521 422006..423718 1 NC_002951.2 hypothetical protein 423718 3236521 SACOL0416 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185308.1 422006 D 93062 CDS YP_185309.1 57652606 3236522 complement(423810..424466) 1 NC_002951.2 identified by match to protein family HMM PF00902; match to protein family HMM TIGR00945; MttB family protein 424466 3236522 SACOL0417 Staphylococcus aureus subsp. aureus COL MttB family protein YP_185309.1 423810 R 93062 CDS YP_185310.1 57652607 3236523 complement(424528..424743) 1 NC_002951.2 identified by match to protein family HMM PF02416; match to protein family HMM TIGR01411; mttA/Hcf106 family protein 424743 3236523 SACOL0418 Staphylococcus aureus subsp. aureus COL mttA/Hcf106 family protein YP_185310.1 424528 R 93062 CDS YP_185311.1 57652608 3236509 complement(424852..425241) 1 NC_002951.2 hypothetical protein 425241 3236509 SACOL0419 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185311.1 424852 R 93062 CDS YP_185312.1 57652609 3236510 425482..425685 1 NC_002951.2 identified by match to protein family HMM PF01381; Cro/CI family transcriptional regulator 425685 3236510 SACOL0420 Staphylococcus aureus subsp. aureus COL Cro/CI family transcriptional regulator YP_185312.1 425482 D 93062 CDS YP_185313.1 57652610 3236511 425682..426395 1 NC_002951.2 hypothetical protein 426395 3236511 SACOL0421 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185313.1 425682 D 93062 CDS YP_185314.1 57652611 3236512 426420..427262 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 427262 3236512 SACOL0422 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_185314.1 426420 D 93062 CDS YP_185315.1 57652612 3236513 427262..427891 1 NC_002951.2 hypothetical protein 427891 3236513 SACOL0424 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185315.1 427262 D 93062 CDS YP_185316.1 57652613 3236514 complement(428258..429391) 1 NC_002951.2 hypothetical protein 429391 3236514 SACOL0425 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185316.1 428258 R 93062 CDS YP_185317.1 57652614 3236515 429930..431111 1 NC_002951.2 identified by similarity to EGAD:16007; match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; acetyl-CoA acetyltransferase 431111 3236515 SACOL0426 Staphylococcus aureus subsp. aureus COL acetyl-CoA acetyltransferase YP_185317.1 429930 D 93062 CDS YP_185318.1 57652615 3236501 complement(431194..431946) 1 NC_002951.2 identified by match to protein family HMM PF04199; hypothetical protein 431946 3236501 SACOL0427 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185318.1 431194 R 93062 CDS YP_185319.1 57652616 3236502 complement(431989..434217) 1 NC_002951.2 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 434217 metE 3236502 metE Staphylococcus aureus subsp. aureus COL 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_185319.1 431989 R 93062 CDS YP_185320.1 57652617 3236503 complement(434214..436055) 1 NC_002951.2 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase 436055 3236503 SACOL0429 Staphylococcus aureus subsp. aureus COL bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase YP_185320.1 434214 R 93062 CDS YP_185321.1 57652618 3236504 complement(436024..437184) 1 NC_002951.2 identified by match to protein family HMM PF01053; trans-sulfuration enzyme family protein 437184 3236504 SACOL0430 Staphylococcus aureus subsp. aureus COL trans-sulfuration enzyme family protein YP_185321.1 436024 R 93062 CDS YP_185322.1 57652619 3236505 complement(437181..438284) 1 NC_002951.2 identified by match to protein family HMM PF01053; trans-sulfuration enzyme family protein 438284 3236505 SACOL0431 Staphylococcus aureus subsp. aureus COL trans-sulfuration enzyme family protein YP_185322.1 437181 R 93062 CDS YP_185323.1 57652620 3236506 438948..439793 1 NC_002951.2 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; spoOJ protein 439793 3236506 SACOL0432 Staphylococcus aureus subsp. aureus COL spoOJ protein YP_185323.1 438948 D 93062 CDS YP_185324.1 57652621 3236507 439950..440831 1 NC_002951.2 identified by similarity to SP:P75783; match to protein family HMM PF00924; hypothetical protein 440831 3236507 SACOL0433 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185324.1 439950 D 93062 CDS YP_185325.1 57652622 3236508 440861..441064 1 NC_002951.2 identified by similarity to GP:10176677; match to protein family HMM PF06107; hypothetical protein 441064 3236508 SACOL0434 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185325.1 440861 D 93062 CDS YP_185326.1 57652623 3236494 441076..442173 1 NC_002951.2 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 442173 3236494 SACOL0435 Staphylococcus aureus subsp. aureus COL GTP-dependent nucleic acid-binding protein EngD YP_185326.1 441076 D 93062 CDS YP_185327.1 57652624 3236495 complement(442259..442450) 1 NC_002951.2 identified by similarity to GB:AAO06017.1; hypothetical protein 442450 3236495 SACOL0436 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185327.1 442259 R 93062 CDS YP_185328.2 161353537 3236496 442694..442990 1 NC_002951.2 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 442990 rpsF 3236496 rpsF Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S6 YP_185328.2 442694 D 93062 CDS YP_185329.1 57652626 3236497 443011..443514 1 NC_002951.2 identified by similarity to EGAD:17778; match to protein family HMM PF00436; match to protein family HMM TIGR00621; single-stranded DNA-binding protein 443514 ssb2 3236497 ssb2 Staphylococcus aureus subsp. aureus COL single-stranded DNA-binding protein YP_185329.1 443011 D 93062 CDS YP_185330.1 57652627 3236498 443566..443808 1 NC_002951.2 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 443808 rpsR 3236498 rpsR Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S18 YP_185330.1 443566 D 93062 CDS YP_185331.1 57652628 3236499 complement(444074..445012) 1 NC_002951.2 identified by similarity to GP:4894254; hypothetical protein 445012 3236499 SACOL0440 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185331.1 444074 R 93062 CDS YP_185332.1 57652629 3236485 445958..446569 1 NC_002951.2 enterotoxin 446569 3236485 SACOL0442 Staphylococcus aureus subsp. aureus COL enterotoxin YP_185332.1 445958 D 93062 CDS YP_185333.1 57652630 3236486 446938..447306 1 NC_002951.2 identified by match to protein family HMM PF06486; match to protein family HMM TIGR01655; hypothetical protein 447306 3236486 SACOL0443 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185333.1 446938 D 93062 CDS YP_185334.1 57652631 3236487 447487..448059 1 NC_002951.2 identified by match to protein family HMM PF03413; hypothetical protein 448059 3236487 SACOL0444 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185334.1 447487 D 93062 CDS YP_185335.1 57652632 3236488 complement(448197..448460) 1 NC_002951.2 identified by similarity to GB:AAO06012.1; hypothetical protein 448460 3236488 SACOL0445 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185335.1 448197 R 93062 CDS YP_185336.1 57652633 3236489 448760..449011 1 NC_002951.2 identified by match to protein family HMM PF04226; hypothetical protein 449011 3236489 SACOL0446 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185336.1 448760 D 93062 CDS YP_185337.1 57652634 3236490 449437..450018 1 NC_002951.2 identified by match to protein family HMM PF00300; phosphoglycerate mutase 450018 3236490 SACOL0447 Staphylococcus aureus subsp. aureus COL phosphoglycerate mutase YP_185337.1 449437 D 93062 CDS YP_185338.1 57652635 3236491 complement(450084..450467) 1 NC_002951.2 hypothetical protein 450467 3236491 SACOL0448 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185338.1 450084 R 93062 CDS YP_185339.1 57652636 3236492 complement(450722..451348) 1 NC_002951.2 hypothetical protein 451348 3236492 SACOL0449 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185339.1 450722 R 93062 CDS YP_185340.1 57652637 3236478 complement(451421..451714) 1 NC_002951.2 hypothetical protein 451714 3236478 SACOL0450 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185340.1 451421 R 93062 CDS YP_185341.1 57652638 3236479 complement(451793..453316) 1 NC_002951.2 identified by similarity to EGAD:30995; match to protein family HMM PF00070; alkyl hydroperoxide reductase subunit F 453316 ahpF 3236479 ahpF Staphylococcus aureus subsp. aureus COL alkyl hydroperoxide reductase subunit F YP_185341.1 451793 R 93062 CDS YP_185342.1 57652639 3236480 complement(453332..453901) 1 NC_002951.2 identified by similarity to EGAD:37649; match to protein family HMM PF00578; alkyl hydroperoxide reductase subunit C 453901 ahpC 3236480 ahpC Staphylococcus aureus subsp. aureus COL alkyl hydroperoxide reductase subunit C YP_185342.1 453332 R 93062 CDS YP_185343.1 57652640 3236481 454393..455148 1 NC_002951.2 identified by similarity to EGAD:18715; match to protein family HMM PF00881; NAD(P)H-flavin oxidoreductase 455148 3236481 SACOL0453 Staphylococcus aureus subsp. aureus COL NAD(P)H-flavin oxidoreductase YP_185343.1 454393 D 93062 CDS YP_185344.1 57652641 3236482 complement(455229..456617) 1 NC_002951.2 identified by match to protein family HMM PF00375; sodium:dicarboxylate symporter family protein 456617 3236482 SACOL0454 Staphylococcus aureus subsp. aureus COL sodium:dicarboxylate symporter family protein YP_185344.1 455229 R 93062 CDS YP_185345.1 57652642 3236483 complement(457594..458550) 1 NC_002951.2 identified by similarity to SP:Q8CQQ7; hypothetical protein 458550 3236483 SACOL0455 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185345.1 457594 R 93062 CDS YP_185346.1 57652643 3236484 complement(458668..459330) 1 NC_002951.2 identified by similarity to GB:AAO05995.1; hypothetical protein 459330 3236484 SACOL0456 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185346.1 458668 R 93062 CDS YP_185347.1 57652644 3236471 complement(459473..459880) 1 NC_002951.2 identified by similarity to GB:AAO05994.1; hypothetical protein 459880 3236471 SACOL0457 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185347.1 459473 R 93062 CDS YP_185348.1 57652645 3236472 460392..460970 1 NC_002951.2 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 460970 xpt 3236472 xpt Staphylococcus aureus subsp. aureus COL xanthine phosphoribosyltransferase YP_185348.1 460392 D 93062 CDS YP_185349.1 57652646 3236473 460970..462238 1 NC_002951.2 identified by similarity to EGAD:30678; match to protein family HMM PF00860; match to protein family HMM TIGR00801; xanthine permease 462238 pbuX 3236473 pbuX Staphylococcus aureus subsp. aureus COL xanthine permease YP_185349.1 460970 D 93062 CDS YP_185350.1 57652647 3236474 462276..463742 1 NC_002951.2 identified by similarity to SP:P21879; match to protein family HMM PF00478; match to protein family HMM PF00571; match to protein family HMM TIGR01302; inosine-5'-monophosphate dehydrogenase 463742 guaB 3236474 guaB Staphylococcus aureus subsp. aureus COL inosine-5'-monophosphate dehydrogenase YP_185350.1 462276 D 93062 CDS YP_185351.1 57652648 3236475 463767..465308 1 NC_002951.2 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 465308 guaA 3236475 guaA Staphylococcus aureus subsp. aureus COL GMP synthase YP_185351.1 463767 D 93062 CDS YP_185352.1 57652649 3236476 complement(465421..465957) 1 NC_002951.2 hypothetical protein 465957 3236476 SACOL0462 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185352.1 465421 R 93062 CDS YP_185353.1 57652650 3236477 complement(466350..467054) 1 NC_002951.2 hypothetical protein 467054 3236477 SACOL0463 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185353.1 466350 R 93062 CDS YP_185354.1 57652651 3236467 complement(467453..467725) 1 NC_002951.2 identified by match to protein family HMM PF01527; IS3 family transposase 467725 3236467 SACOL0464 Staphylococcus aureus subsp. aureus COL IS3 family transposase YP_185354.1 467453 R 93062 CDS YP_185355.1 57651306 3236792 complement(467986..468138) 1 NC_002951.2 hypothetical protein 468138 3236792 SACOL0465 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185355.1 467986 R 93062 CDS YP_185356.1 57651307 3236793 complement(468662..469021) 1 NC_002951.2 identified by match to protein family HMM PF06993; hypothetical protein 469021 3236793 SACOL0466 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185356.1 468662 R 93062 CDS YP_185357.1 57651308 3236953 complement(469040..469885) 1 NC_002951.2 hypothetical protein 469885 3236953 SACOL0467 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185357.1 469040 R 93062 CDS YP_185358.1 57651309 3236954 470357..471037 1 NC_002951.2 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 471037 3236954 SACOL0468 Staphylococcus aureus subsp. aureus COL superantigen-like protein YP_185358.1 470357 D 93062 CDS YP_185359.1 57651310 3236955 471323..472018 1 NC_002951.2 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 472018 3236955 SACOL0469 Staphylococcus aureus subsp. aureus COL superantigen-like protein YP_185359.1 471323 D 93062 CDS YP_185360.1 57651311 3236956 472309..473367 1 NC_002951.2 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 473367 3236956 SACOL0470 Staphylococcus aureus subsp. aureus COL superantigen-like protein YP_185360.1 472309 D 93062 CDS YP_185361.1 57651312 3236957 473486..473623 1 NC_002951.2 hypothetical protein 473623 3236957 SACOL0471 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185361.1 473486 D 93062 CDS YP_185362.1 57651313 3236958 473732..474658 1 NC_002951.2 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 474658 3236958 SACOL0472 Staphylococcus aureus subsp. aureus COL superantigen-like protein YP_185362.1 473732 D 93062 CDS YP_185363.1 57651314 3236959 475038..475736 1 NC_002951.2 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 475736 3236959 SACOL0473 Staphylococcus aureus subsp. aureus COL superantigen-like protein YP_185363.1 475038 D 93062 CDS YP_185364.1 57651315 3236960 476102..476785 1 NC_002951.2 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 476785 3236960 SACOL0474 Staphylococcus aureus subsp. aureus COL superantigen-like protein YP_185364.1 476102 D 93062 CDS YP_185365.1 57651316 3236961 complement(476870..476971) 1 NC_002951.2 hypothetical protein 476971 3236961 SACOL0475 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185365.1 476870 R 93062 CDS YP_185366.1 57651317 3236962 477049..478605 1 NC_002951.2 identified by match to protein family HMM PF02384; match to protein family HMM PF02506; match to protein family HMM TIGR00497; type I restriction-modification system, M subunit 478605 hsdM1 3236962 hsdM1 Staphylococcus aureus subsp. aureus COL type I restriction-modification system, M subunit YP_185366.1 477049 D 93062 CDS YP_185367.1 57651318 3236963 478598..479809 1 NC_002951.2 identified by match to protein family HMM PF01420; type I restriction-modification system S subunit 479809 3236963 SACOL0477 Staphylococcus aureus subsp. aureus COL type I restriction-modification system S subunit YP_185367.1 478598 D 93062 CDS YP_185368.1 57651319 3236964 480192..480869 1 NC_002951.2 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 480869 3236964 SACOL0478 Staphylococcus aureus subsp. aureus COL superantigen-like protein YP_185368.1 480192 D 93062 CDS YP_185369.1 57651320 3236965 480891..482399 1 NC_002951.2 identified by match to protein family HMM TIGR01168; hypothetical protein 482399 3236965 SACOL0479 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185369.1 480891 D 93062 CDS YP_185370.1 57651321 3236966 complement(482503..482811) 1 NC_002951.2 hypothetical protein 482811 3236966 SACOL0480 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185370.1 482503 R 93062 CDS YP_185371.1 57651322 3236967 483149..483949 1 NC_002951.2 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742; hypothetical protein 483949 3236967 SACOL0481 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185371.1 483149 D 93062 CDS YP_185372.1 57651323 3236968 483981..484772 1 NC_002951.2 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742; hypothetical protein 484772 3236968 SACOL0482 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185372.1 483981 D 93062 CDS YP_185373.1 57651324 3236969 484842..485618 1 NC_002951.2 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742; staphyloccoccus tandem lipoprotein 485618 3236969 SACOL0483 Staphylococcus aureus subsp. aureus COL staphyloccoccus tandem lipoprotein YP_185373.1 484842 D 93062 CDS YP_185374.1 57651325 3236970 485794..486609 1 NC_002951.2 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742; hypothetical protein 486609 3236970 SACOL0484 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185374.1 485794 D 93062 CDS YP_185375.1 57651326 3236971 486628..487413 1 NC_002951.2 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742; hypothetical protein 487413 3236971 SACOL0485 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185375.1 486628 D 93062 CDS YP_185376.1 57651327 3236972 487593..488408 1 NC_002951.2 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742; hypothetical protein 488408 3236972 SACOL0486 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185376.1 487593 D 93062 CDS YP_185377.1 57651328 3236973 488401..489726 1 NC_002951.2 hypothetical protein 489726 3236973 SACOL0487 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185377.1 488401 D 93062 CDS YP_185378.1 57651329 3236974 489723..490046 1 NC_002951.2 hypothetical protein 490046 3236974 SACOL0488 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185378.1 489723 D 93062 CDS YP_185379.1 57651330 3236975 490065..490379 1 NC_002951.2 hypothetical protein 490379 3236975 SACOL0489 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185379.1 490065 D 93062 CDS YP_185380.1 57651331 3236976 complement(490669..490929) 1 NC_002951.2 hypothetical protein 490929 3236976 SACOL0490 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185380.1 490669 R 93062 CDS YP_185381.1 57651332 3236977 491048..492250 1 NC_002951.2 identified by match to protein family HMM PF02492; match to protein family HMM PF07683; cobalamin synthesis protein 492250 3236977 SACOL0491 Staphylococcus aureus subsp. aureus COL cobalamin synthesis protein YP_185381.1 491048 D 93062 CDS YP_185382.1 57651333 3236978 493838..495322 1 NC_002951.2 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit 5 495322 nuoF 3236978 nuoF Staphylococcus aureus subsp. aureus COL NADH dehydrogenase subunit 5 YP_185382.1 493838 D 93062 CDS YP_185383.1 57651334 3236979 495335..498040 1 NC_002951.2 hypothetical protein 498040 3236979 SACOL0495 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185383.1 495335 D 93062 CDS YP_185384.1 57651335 3236980 498202..498564 1 NC_002951.2 hypothetical protein 498564 3236980 SACOL0496 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185384.1 498202 D 93062 CDS YP_185385.1 57651336 3236981 complement(498793..499140) 1 NC_002951.2 hypothetical protein 499140 3236981 SACOL0497 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185385.1 498793 R 93062 CDS YP_185386.1 57651337 3236982 499247..499921 1 NC_002951.2 identified by match to protein family HMM PF01569; hypothetical protein 499921 3236982 SACOL0498 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185386.1 499247 D 93062 CDS YP_185387.1 57651338 3236983 499958..500692 1 NC_002951.2 hypothetical protein 500692 3236983 SACOL0499 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185387.1 499958 D 93062 CDS YP_185388.1 57651339 3236984 500802..500918 1 NC_002951.2 hypothetical protein 500918 3236984 SACOL0500 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185388.1 500802 D 93062 CDS YP_185389.1 57651340 3236985 501148..502485 1 NC_002951.2 identified by match to protein family HMM PF00209; sodium-dependent transporter 502485 3236985 SACOL0501 Staphylococcus aureus subsp. aureus COL sodium-dependent transporter YP_185389.1 501148 D 93062 CDS YP_185390.1 57651341 3236986 502702..503616 1 NC_002951.2 identified by similarity to EGAD:89450; match to protein family HMM PF00291; cysteine synthase/cystathionine beta-synthase 503616 3236986 SACOL0502 Staphylococcus aureus subsp. aureus COL cysteine synthase/cystathionine beta-synthase YP_185390.1 502702 D 93062 CDS YP_185391.1 57651342 3237078 503600..504742 1 NC_002951.2 identified by match to protein family HMM PF01053; trans-sulfuration enzyme family protein 504742 3237078 SACOL0503 Staphylococcus aureus subsp. aureus COL trans-sulfuration enzyme family protein YP_185391.1 503600 D 93062 CDS YP_185392.1 57651343 3237079 505036..506061 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 506061 3237079 SACOL0504 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_185392.1 505036 D 93062 CDS YP_185393.1 57651344 3237080 506065..506724 1 NC_002951.2 identified by match to protein family HMM PF00528; ABC transporter permease 506724 3237080 SACOL0505 Staphylococcus aureus subsp. aureus COL ABC transporter permease YP_185393.1 506065 D 93062 CDS YP_185394.1 57651345 3237081 506761..507603 1 NC_002951.2 identified by match to protein family HMM PF03180; ABC transporter substrate-binding protein 507603 3237081 SACOL0506 Staphylococcus aureus subsp. aureus COL ABC transporter substrate-binding protein YP_185394.1 506761 D 93062 CDS YP_185395.1 57651346 3237082 507935..508939 1 NC_002951.2 identified by match to protein family HMM PF01476; match to protein family HMM PF05257; LysM domain-containing protein 508939 3237082 SACOL0507 Staphylococcus aureus subsp. aureus COL LysM domain-containing protein YP_185395.1 507935 D 93062 CDS YP_185396.1 57651347 3237083 complement(509124..509393) 1 NC_002951.2 identified by similarity to GB:AAO05959.1; hypothetical protein 509393 3237083 SACOL0508 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185396.1 509124 R 93062 CDS YP_185397.1 57651348 3237084 509542..509937 1 NC_002951.2 identified by match to protein family HMM PF00293; MutT/nudix family protein 509937 3237084 SACOL0509 Staphylococcus aureus subsp. aureus COL MutT/nudix family protein YP_185397.1 509542 D 93062 CDS YP_185398.1 57651349 3237085 509927..510412 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 510412 3237085 SACOL0510 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_185398.1 509927 D 93062 CDS YP_185399.1 57651350 3237086 complement(510581..511363) 1 NC_002951.2 hypothetical protein 511363 3237086 SACOL0511 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185399.1 510581 R 93062 CDS YP_185400.1 57651351 3237087 complement(511360..512472) 1 NC_002951.2 hypothetical protein 512472 3237087 SACOL0512 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185400.1 511360 R 93062 CDS YP_185401.1 57651352 3237088 complement(512593..513477) 1 NC_002951.2 identified by similarity to EGAD:6257; match to protein family HMM PF00126; transcriptional regulatory protein GltC 513477 gltC 3237088 gltC Staphylococcus aureus subsp. aureus COL transcriptional regulatory protein GltC YP_185401.1 512593 R 93062 CDS YP_185402.1 57651353 3237089 513658..518157 1 NC_002951.2 identified by similarity to EGAD:109137; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04897; match to protein family HMM PF04898; glutamate synthase 518157 gltB 3237089 gltB Staphylococcus aureus subsp. aureus COL glutamate synthase YP_185402.1 513658 D 93062 CDS YP_185403.1 57651354 3237090 518175..519638 1 NC_002951.2 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase 519638 gltD 3237090 gltD Staphylococcus aureus subsp. aureus COL glutamate synthase YP_185403.1 518175 D 93062 CDS YP_185404.1 57651355 3237091 520470..521897 1 NC_002951.2 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR01992; PTS system, IIBC components 521897 3237091 SACOL0516 Staphylococcus aureus subsp. aureus COL PTS system, IIBC components YP_185404.1 520470 D 93062 CDS YP_185405.1 57651356 3237092 521961..523601 1 NC_002951.2 identified by match to protein family HMM PF00128; alpha-amylase 523601 3237092 SACOL0517 Staphylococcus aureus subsp. aureus COL alpha-amylase YP_185405.1 521961 D 93062 CDS YP_185406.1 57651357 3237093 523626..524354 1 NC_002951.2 identified by similarity to EGAD:37606; match to protein family HMM PF00392; match to protein family HMM PF07702; GntR family transcriptional regulator 524354 3237093 SACOL0518 Staphylococcus aureus subsp. aureus COL GntR family transcriptional regulator YP_185406.1 523626 D 93062 CDS YP_185407.1 57651358 3237094 524993..525517 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 525517 3237094 SACOL0519 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_185407.1 524993 D 93062 CDS YP_185408.1 57651359 3237095 525586..527283 1 NC_002951.2 identified by similarity to SP:P09122; match to protein family HMM PF00004; DNA polymerase III subunits gamma and tau 527283 dnaX 3237095 dnaX Staphylococcus aureus subsp. aureus COL DNA polymerase III subunits gamma and tau YP_185408.1 525586 D 93062 CDS YP_185409.1 57651360 3237096 527373..527690 1 NC_002951.2 identified by similarity to EGAD:19844; match to protein family HMM PF02575; match to protein family HMM TIGR00103; hypothetical protein 527690 3237096 SACOL0521 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185409.1 527373 D 93062 CDS YP_185410.1 57651361 3237097 527697..528293 1 NC_002951.2 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 528293 recR 3237097 recR Staphylococcus aureus subsp. aureus COL recombination protein RecR YP_185410.1 527697 D 93062 CDS YP_185411.1 57651362 3237098 535057..536394 1 NC_002951.2 identified by match to protein family HMM PF01276; Orn/Lys/Arg decarboxylase 536394 3237098 SACOL0523 Staphylococcus aureus subsp. aureus COL Orn/Lys/Arg decarboxylase YP_185411.1 535057 D 93062 CDS YP_185412.1 57651363 3237099 536396..537013 1 NC_002951.2 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 537013 tmk 3237099 tmk Staphylococcus aureus subsp. aureus COL thymidylate kinase YP_185412.1 536396 D 93062 CDS YP_185413.1 57651364 3237100 537041..537370 1 NC_002951.2 identified by similarity to GP:10172655; match to protein family HMM PF06153; hypothetical protein 537370 3237100 SACOL0525 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185413.1 537041 D 93062 CDS YP_185414.1 57651365 3237101 537584..538510 1 NC_002951.2 identified by similarity to EGAD:13071; DNA polymerase III subunit delta' 538510 3237101 SACOL0526 Staphylococcus aureus subsp. aureus COL DNA polymerase III subunit delta' YP_185414.1 537584 D 93062 CDS YP_185415.1 57651366 3237102 538511..539314 1 NC_002951.2 identified by match to protein family HMM PF04468; hypothetical protein 539314 3237102 SACOL0527 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185415.1 538511 D 93062 CDS YP_185416.1 57651367 3237103 539331..539678 1 NC_002951.2 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 539678 3237103 SACOL0528 Staphylococcus aureus subsp. aureus COL DNA replication intiation control protein YabA YP_185416.1 539331 D 93062 CDS YP_185417.1 57651368 3237104 539952..540677 1 NC_002951.2 hypothetical protein 540677 3237104 SACOL0529 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185417.1 539952 D 93062 CDS YP_185418.1 57651369 3237105 540670..540918 1 NC_002951.2 identified by match to protein family HMM PF01541; hypothetical protein 540918 3237105 SACOL0530 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185418.1 540670 D 93062 CDS YP_185419.1 57651370 3237106 540920..541759 1 NC_002951.2 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096; tetrapyrrole methylase 541759 3237106 SACOL0531 Staphylococcus aureus subsp. aureus COL tetrapyrrole methylase YP_185419.1 540920 D 93062 CDS YP_185420.1 57651371 3237107 complement(541784..541939) 1 NC_002951.2 hypothetical protein 541939 3237107 SACOL0532 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185420.1 541784 R 93062 CDS YP_185421.1 57651372 3237108 542044..544017 1 NC_002951.2 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 544017 metS 3237108 metS Staphylococcus aureus subsp. aureus COL methionyl-tRNA synthetase YP_185421.1 542044 D 93062 CDS YP_185422.1 57651373 3237109 544048..544821 1 NC_002951.2 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010; TatD family deoxyribonuclease 544821 3237109 SACOL0534 Staphylococcus aureus subsp. aureus COL TatD family deoxyribonuclease YP_185422.1 544048 D 93062 CDS YP_185423.1 57651374 3237110 544988..545524 1 NC_002951.2 identified by match to protein family HMM PF01751; match to protein family HMM TIGR00334; hypothetical protein 545524 3237110 SACOL0535 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185423.1 544988 D 93062 CDS YP_185424.1 57651375 3237111 545535..546428 1 NC_002951.2 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 546428 ksgA 3237111 ksgA Staphylococcus aureus subsp. aureus COL dimethyladenosine transferase YP_185424.1 545535 D 93062 CDS YP_185425.1 57651376 3237112 546528..546791 1 NC_002951.2 identified by similarity to EGAD:13222; match to protein family HMM PF06257; hypothetical protein 546791 3237112 SACOL0537 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185425.1 546528 D 93062 CDS YP_185426.1 57651377 3237113 547101..547949 1 NC_002951.2 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 547949 ipk 3237113 ipk Staphylococcus aureus subsp. aureus COL 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_185426.1 547101 D 93062 CDS YP_185427.1 57651378 3237114 547963..548787 1 NC_002951.2 identified by similarity to EGAD:16043; match to protein family HMM PF00156; match to protein family HMM TIGR01743; pur operon repressor 548787 purR 3237114 purR Staphylococcus aureus subsp. aureus COL pur operon repressor YP_185427.1 547963 D 93062 CDS YP_185428.1 57650037 3238252 548804..549184 1 NC_002951.2 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004; endoribonuclease L-PSP 549184 3238252 SACOL0540 Staphylococcus aureus subsp. aureus COL endoribonuclease L-PSP YP_185428.1 548804 D 93062 CDS YP_185429.1 57650038 3238406 549256..549558 1 NC_002951.2 stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus; regulatory protein SpoVG 549558 spoVG 3238406 spoVG Staphylococcus aureus subsp. aureus COL regulatory protein SpoVG YP_185429.1 549256 D 93062 CDS YP_185430.1 57650039 3238520 549748..549879 1 NC_002951.2 hypothetical protein 549879 3238520 SACOL0542 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185430.1 549748 D 93062 CDS YP_185431.1 57650040 3238384 549902..551254 1 NC_002951.2 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 551254 glmU 3238384 glmU Staphylococcus aureus subsp. aureus COL bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_185431.1 549902 D 93062 CDS YP_185432.1 57650041 3238302 551401..552366 1 NC_002951.2 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 552366 prsA 3238302 prsA Staphylococcus aureus subsp. aureus COL ribose-phosphate pyrophosphokinase YP_185432.1 551401 D 93062 CDS YP_185433.1 57650042 3238045 552516..553169 1 NC_002951.2 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 553169 rplY 3238045 rplY Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L25/general stress protein Ctc YP_185433.1 552516 D 93062 CDS YP_185434.1 57650043 3238366 553480..554052 1 NC_002951.2 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 554052 pth 3238366 pth Staphylococcus aureus subsp. aureus COL peptidyl-tRNA hydrolase YP_185434.1 553480 D 93062 CDS YP_185435.1 57650044 3238490 554052..557558 1 NC_002951.2 identified by similarity to EGAD:14131; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580; transcription-repair coupling factor 557558 mfd 3238490 mfd Staphylococcus aureus subsp. aureus COL transcription-repair coupling factor YP_185435.1 554052 D 93062 CDS YP_185436.1 57650045 3238257 557548..559074 1 NC_002951.2 identified by match to protein family HMM PF01943; polysaccharide biosynthesis protein 559074 3238257 SACOL0548 Staphylococcus aureus subsp. aureus COL polysaccharide biosynthesis protein YP_185436.1 557548 D 93062 CDS YP_185437.1 57650046 3238372 559074..560267 1 NC_002951.2 identified by match to protein family HMM PF00590; match to protein family HMM PF03819; tetrapyrrole methylase 560267 3238372 SACOL0549 Staphylococcus aureus subsp. aureus COL tetrapyrrole methylase YP_185437.1 559074 D 93062 CDS YP_185438.1 57650047 3238327 560264..560527 1 NC_002951.2 identified by match to protein family HMM PF01479; S4 domain-containing protein 560527 3238327 SACOL0550 Staphylococcus aureus subsp. aureus COL S4 domain-containing protein YP_185438.1 560264 D 93062 CDS YP_185439.1 57650048 3238149 560545..560937 1 NC_002951.2 identified by similarity to EGAD:12437; match to protein family HMM PF04977; cell-division protein divIC 560937 3238149 SACOL0551 Staphylococcus aureus subsp. aureus COL cell-division protein divIC YP_185439.1 560545 D 93062 CDS YP_185440.1 57651384 3237120 561042..561443 1 NC_002951.2 identified by similarity to SP:P80870; match to protein family HMM PF00575; hypothetical protein 561443 3237120 SACOL0552 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185440.1 561042 D 93062 CDS YP_185441.1 57651385 3237121 561623..562918 1 NC_002951.2 identified by similarity to EGAD:18381; match to protein family HMM PF01171; hypothetical protein 562918 3237121 SACOL0553 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185441.1 561623 D 93062 CDS YP_185442.1 57651386 3237122 562923..563462 1 NC_002951.2 identified by similarity to EGAD:18056; match to protein family HMM PF00156; match to protein family HMM TIGR01203; hypoxanthine phosphoribosyltransferase 563462 hpt 3237122 hpt Staphylococcus aureus subsp. aureus COL hypoxanthine phosphoribosyltransferase YP_185442.1 562923 D 93062 CDS YP_185443.1 57651387 3237123 563719..565812 1 NC_002951.2 identified by similarity to EGAD:13183; match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM PF06480; match to protein family HMM TIGR01241; cell division protein FtsH 565812 3237123 SACOL0555 Staphylococcus aureus subsp. aureus COL cell division protein FtsH YP_185443.1 563719 D 93062 CDS YP_185444.1 57651388 3237124 566041..566922 1 NC_002951.2 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 566922 hslO 3237124 hslO Staphylococcus aureus subsp. aureus COL Hsp33-like chaperonin YP_185444.1 566041 D 93062 CDS YP_185445.1 57651389 3237125 567101..568033 1 NC_002951.2 identified by similarity to SP:P37887; match to protein family HMM PF00291; match to protein family HMM TIGR01136; match to protein family HMM TIGR01139; cysteine synthase 568033 cysK 3237125 cysK Staphylococcus aureus subsp. aureus COL cysteine synthase YP_185445.1 567101 D 93062 CDS YP_185446.1 57651390 3237126 568249..569052 1 NC_002951.2 identified by similarity to SP:O05701; match to protein family HMM PF00809; match to protein family HMM TIGR01496; dihydropteroate synthase 569052 folP 3237126 folP Staphylococcus aureus subsp. aureus COL dihydropteroate synthase YP_185446.1 568249 D 93062 CDS YP_185447.1 57651391 3237127 569030..569395 1 NC_002951.2 identified by similarity to SP:P56740; match to protein family HMM PF02152; match to protein family HMM TIGR00525; match to protein family HMM TIGR00526; dihydroneopterin aldolase 569395 folB 3237127 folB Staphylococcus aureus subsp. aureus COL dihydroneopterin aldolase YP_185447.1 569030 D 93062 CDS YP_185448.1 57651392 3237128 569392..569868 1 NC_002951.2 identified by similarity to EGAD:18680; match to protein family HMM PF01288; match to protein family HMM TIGR01498; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 569868 folK 3237128 folK Staphylococcus aureus subsp. aureus COL 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_185448.1 569392 D 93062 CDS YP_185449.1 57651393 3237129 570262..570354 1 NC_002951.2 hypothetical protein 570354 3237129 SACOL0561 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185449.1 570262 D 93062 CDS YP_185450.1 57651394 3237130 570407..571894 1 NC_002951.2 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 571894 lysS 3237130 lysS Staphylococcus aureus subsp. aureus COL lysyl-tRNA synthetase YP_185450.1 570407 D 93062 CDS YP_185451.1 57651395 3237613 complement(583479..584861) 1 NC_002951.2 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 584861 3237613 SACOL0563 Staphylococcus aureus subsp. aureus COL GntR family transcriptional regulator YP_185451.1 583479 R 93062 CDS YP_185452.1 57651396 3237614 584965..585852 1 NC_002951.2 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 585852 3237614 SACOL0564 Staphylococcus aureus subsp. aureus COL pyridoxal biosynthesis lyase PdxS YP_185452.1 584965 D 93062 CDS YP_185453.1 57651397 3237615 585856..586416 1 NC_002951.2 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 586416 3237615 SACOL0565 Staphylococcus aureus subsp. aureus COL glutamine amidotransferase subunit PdxT YP_185453.1 585856 D 93062 CDS YP_185454.1 57651398 3237616 complement(586624..587838) 1 NC_002951.2 identified by similarity to EGAD:6216; match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; nucleoside permease NupC 587838 nupC 3237616 nupC Staphylococcus aureus subsp. aureus COL nucleoside permease NupC YP_185454.1 586624 R 93062 CDS YP_185455.1 57651399 3237617 587996..588457 1 NC_002951.2 identified by similarity to EGAD:23972; match to protein family HMM PF05848; transcriptional regulator CtsR 588457 ctsR 3237617 ctsR Staphylococcus aureus subsp. aureus COL transcriptional regulator CtsR YP_185455.1 587996 D 93062 CDS YP_185456.1 57651400 3238526 588476..589042 1 NC_002951.2 identified by similarity to GP:7007431; match to protein family HMM PF02151; hypothetical protein 589042 3238526 SACOL0568 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185456.1 588476 D 93062 CDS YP_185457.1 57651401 3238527 589032..590039 1 NC_002951.2 identified by match to protein family HMM PF00217; ATP:guanido phosphotransferase 590039 3238527 SACOL0569 Staphylococcus aureus subsp. aureus COL ATP:guanido phosphotransferase YP_185457.1 589032 D 93062 CDS YP_185458.1 57651402 3238529 592995..594359 1 NC_002951.2 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 594359 radA 3238529 radA Staphylococcus aureus subsp. aureus COL DNA repair protein RadA YP_185458.1 592995 D 93062 CDS YP_185459.1 57651403 3238530 594384..595457 1 NC_002951.2 identified by similarity to OMNI:NTL01BH0107; match to protein family HMM PF01850; match to protein family HMM PF01938; PIN/TRAM domain-containing protein 595457 3238530 SACOL0573 Staphylococcus aureus subsp. aureus COL PIN/TRAM domain-containing protein YP_185459.1 594384 D 93062 CDS YP_185460.1 57651404 3238712 596014..597468 1 NC_002951.2 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 597468 gltX 3238712 gltX Staphylococcus aureus subsp. aureus COL glutamyl-tRNA synthetase YP_185460.1 596014 D 93062 CDS YP_185461.1 57651405 3235986 597897..598538 1 NC_002951.2 identified by similarity to EGAD:98265; match to protein family HMM PF00132; match to protein family HMM TIGR01172; serine acetyltransferase 598538 cysE 3235986 cysE Staphylococcus aureus subsp. aureus COL serine acetyltransferase YP_185461.1 597897 D 93062 CDS YP_185462.1 57651406 3235987 598522..599922 1 NC_002951.2 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 599922 cysS 3235987 cysS Staphylococcus aureus subsp. aureus COL cysteinyl-tRNA synthetase YP_185462.1 598522 D 93062 CDS YP_185463.1 57651407 3235988 599915..600319 1 NC_002951.2 identified by similarity to EGAD:108189; match to protein family HMM PF05948; hypothetical protein 600319 3235988 SACOL0577 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185463.1 599915 D 93062 CDS YP_185464.1 57651408 3235989 600327..601073 1 NC_002951.2 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00186; RNA methyltransferase 601073 3235989 SACOL0578 Staphylococcus aureus subsp. aureus COL RNA methyltransferase YP_185464.1 600327 D 93062 CDS YP_185465.1 57651409 3236214 601073..601597 1 NC_002951.2 identified by similarity to EGAD:14028; match to protein family HMM PF05991; hypothetical protein 601597 3236214 SACOL0579 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185465.1 601073 D 93062 CDS YP_185466.1 57651410 3236215 601678..602247 1 NC_002951.2 identified by similarity to OMNI:EF0049; match to protein family HMM PF04542; hypothetical protein 602247 3236215 SACOL0580 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185466.1 601678 D 93062 CDS YP_185467.1 57651411 3236216 602561..602743 1 NC_002951.2 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 602743 secE 3236216 secE Staphylococcus aureus subsp. aureus COL preprotein translocase subunit SecE YP_185467.1 602561 D 93062 CDS YP_185468.1 57651412 3236217 602756..603304 1 NC_002951.2 identified by similarity to EGAD:9622; match to protein family HMM PF00467; match to protein family HMM PF02357; match to protein family HMM TIGR00922; transcription antitermination protein 603304 nusG 3236217 nusG Staphylococcus aureus subsp. aureus COL transcription antitermination protein YP_185468.1 602756 D 93062 CDS YP_185469.1 57651413 3236218 603476..603907 1 NC_002951.2 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 603907 rplK 3236218 rplK Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L11 YP_185469.1 603476 D 93062 CDS YP_185470.1 57651414 3236230 604115..604807 1 NC_002951.2 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 604807 rplA 3236230 rplA Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L1 YP_185470.1 604115 D 93062 CDS YP_185471.1 57651415 3236231 605079..605579 1 NC_002951.2 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 605579 rplJ 3236231 rplJ Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L10 YP_185471.1 605079 D 93062 CDS YP_185472.1 57651416 3236232 605622..605990 1 NC_002951.2 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 605990 rplL 3236232 rplL Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L7/L12 YP_185472.1 605622 D 93062 CDS YP_185473.1 57651417 3236233 606165..606773 1 NC_002951.2 identified by similarity to GP:10172736; match to protein family HMM PF05175; hypothetical protein 606773 3236233 SACOL0587 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185473.1 606165 D 93062 CDS YP_185474.1 57651418 3236234 606988..610539 1 NC_002951.2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 610539 rpoB 3236234 rpoB Staphylococcus aureus subsp. aureus COL DNA-directed RNA polymerase subunit beta YP_185474.1 606988 D 93062 CDS YP_185475.1 57651419 3236179 610676..614299 1 NC_002951.2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 614299 rpoC 3236179 rpoC Staphylococcus aureus subsp. aureus COL DNA-directed RNA polymerase subunit beta' YP_185475.1 610676 D 93062 CDS YP_185476.1 57651420 3236180 614436..614690 1 NC_002951.2 in Bacillus subtilis this non-essential protein associates with the ribosome; ribosomal protein L7Ae-like 614690 3236180 SACOL0590 Staphylococcus aureus subsp. aureus COL ribosomal protein L7Ae-like YP_185476.1 614436 D 93062 CDS YP_185477.1 57651421 3236181 614788..615201 1 NC_002951.2 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 615201 rpsL 3236181 rpsL Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S12 YP_185477.1 614788 D 93062 CDS YP_185478.1 57651422 3236182 615267..615737 1 NC_002951.2 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 615737 rpsG 3236182 rpsG Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S7 YP_185478.1 615267 D 93062 CDS YP_185479.1 57651423 3236183 615860..617941 1 NC_002951.2 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 617941 fusA 3236183 fusA Staphylococcus aureus subsp. aureus COL elongation factor G YP_185479.1 615860 D 93062 CDS YP_185480.1 57651424 3236433 618158..619342 1 NC_002951.2 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 619342 tuf 3236433 tuf Staphylococcus aureus subsp. aureus COL elongation factor Tu YP_185480.1 618158 D 93062 CDS YP_185481.1 57651425 3236434 complement(619624..620799) 1 NC_002951.2 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; M20/M25/M40 family peptidase 620799 3236434 SACOL0595 Staphylococcus aureus subsp. aureus COL M20/M25/M40 family peptidase YP_185481.1 619624 R 93062 CDS YP_185482.1 57651426 3236435 620970..622157 1 NC_002951.2 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase 622157 3236435 SACOL0596 Staphylococcus aureus subsp. aureus COL 2-amino-3-ketobutyrate coenzyme A ligase YP_185482.1 620970 D 93062 CDS YP_185483.1 57651427 3236436 622423..623301 1 NC_002951.2 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 623301 3236436 SACOL0597 Staphylococcus aureus subsp. aureus COL chaperone protein HchA YP_185483.1 622423 D 93062 CDS YP_185484.1 57651428 3236437 623461..625098 1 NC_002951.2 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 625098 3236437 SACOL0598 Staphylococcus aureus subsp. aureus COL ribulokinase YP_185484.1 623461 D 93062 CDS YP_185485.1 57651429 3236200 625312..626277 1 NC_002951.2 identified by similarity to OMNI:NT01TA1215; hypothetical protein 626277 3236200 SACOL0599 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185485.1 625312 D 93062 CDS YP_185486.1 57651430 3236201 626612..627688 1 NC_002951.2 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 627688 ilvE 3236201 ilvE Staphylococcus aureus subsp. aureus COL branched-chain amino acid aminotransferase YP_185486.1 626612 D 93062 CDS YP_185487.1 57651431 3236202 627661..627834 1 NC_002951.2 hypothetical protein 627834 3236202 SACOL0601 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185487.1 627661 D 93062 CDS YP_185488.1 57651432 3236203 627938..628621 1 NC_002951.2 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; HAD superfamily hydrolase 628621 3236203 SACOL0602 Staphylococcus aureus subsp. aureus COL HAD superfamily hydrolase YP_185488.1 627938 D 93062 CDS YP_185489.1 57651433 3236204 complement(628737..629399) 1 NC_002951.2 identified by match to protein family HMM PF01712; deoxynucleoside kinase 629399 3236204 SACOL0603 Staphylococcus aureus subsp. aureus COL deoxynucleoside kinase YP_185489.1 628737 R 93062 CDS YP_185490.1 57651434 3236258 complement(629392..630009) 1 NC_002951.2 identified by match to protein family HMM PF01712; deoxynucleoside kinase 630009 3236258 SACOL0604 Staphylococcus aureus subsp. aureus COL deoxynucleoside kinase YP_185490.1 629392 R 93062 CDS YP_185491.1 57651435 3236351 630693..631562 1 NC_002951.2 identified by match to protein family HMM PF00702; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; HAD superfamily hydrolase 631562 3236351 SACOL0606 Staphylococcus aureus subsp. aureus COL HAD superfamily hydrolase YP_185491.1 630693 D 93062 CDS YP_185492.1 57651436 3236352 631583..632149 1 NC_002951.2 identified by similarity to GP:10281002; match to protein family HMM PF03358; hypothetical protein 632149 3236352 SACOL0607 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185492.1 631583 D 93062 CDS YP_185493.1 57651437 3236353 632579..635422 1 NC_002951.2 identified by similarity to GP:3550592; match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF05738; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; sdrC protein 635422 sdrC 3236353 sdrC Staphylococcus aureus subsp. aureus COL sdrC protein YP_185493.1 632579 D 93062 CDS YP_185494.1 57651438 3236072 635789..639934 1 NC_002951.2 identified by similarity to GP:3550594; match to protein family HMM PF00746; match to protein family HMM PF02412; match to protein family HMM PF04650; match to protein family HMM PF05738; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; sdrD protein 639934 sdrD 3236072 sdrD Staphylococcus aureus subsp. aureus COL sdrD protein YP_185494.1 635789 D 93062 CDS YP_185495.1 57651439 3236073 640328..643828 1 NC_002951.2 identified by similarity to GP:3550596; match to protein family HMM PF00746; match to protein family HMM PF02412; match to protein family HMM PF04650; match to protein family HMM PF05738; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; sdrE protein 643828 sdrE 3236073 sdrE Staphylococcus aureus subsp. aureus COL sdrE protein YP_185495.1 640328 D 93062 CDS YP_185496.1 57651440 3236074 643947..645419 1 NC_002951.2 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein 645419 3236074 SACOL0611 Staphylococcus aureus subsp. aureus COL glycosyl transferase, group 1 family protein YP_185496.1 643947 D 93062 CDS YP_185497.1 57651441 3236075 complement(645543..647033) 1 NC_002951.2 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein 647033 3236075 SACOL0612 Staphylococcus aureus subsp. aureus COL glycosyl transferase, group 1 family protein YP_185497.1 645543 R 93062 CDS YP_185498.1 57651442 3236076 complement(647315..648193) 1 NC_002951.2 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis; GTP cyclohydrolase 648193 3236076 SACOL0613 Staphylococcus aureus subsp. aureus COL GTP cyclohydrolase YP_185498.1 647315 R 93062 CDS YP_185499.1 57651443 3236168 complement(648206..648871) 1 NC_002951.2 identified by similarity to GP:10175943; match to protein family HMM PF02585; hypothetical protein 648871 3236168 SACOL0614 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185499.1 648206 R 93062 CDS YP_185500.1 57651444 3236740 complement(648885..649247) 1 NC_002951.2 identified by similarity to GP:10175942; hypothetical protein 649247 3236740 SACOL0615 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185500.1 648885 R 93062 CDS YP_185501.1 57651445 3236741 649523..650281 1 NC_002951.2 identified by similarity to EGAD:107403; match to protein family HMM PF01182; glucosamine-6-phosphate isomerase 650281 nagB 3236741 nagB Staphylococcus aureus subsp. aureus COL glucosamine-6-phosphate isomerase YP_185501.1 649523 D 93062 CDS YP_185502.1 57651446 3236742 650358..650990 1 NC_002951.2 identified by similarity to EGAD:30794; match to protein family HMM PF00215; hexulose-6-phosphate synthase 650990 3236742 SACOL0617 Staphylococcus aureus subsp. aureus COL hexulose-6-phosphate synthase YP_185502.1 650358 D 93062 CDS YP_185503.1 57651447 3236743 650992..651540 1 NC_002951.2 identified by match to protein family HMM PF01380; SIS domain-containing protein 651540 3236743 SACOL0618 Staphylococcus aureus subsp. aureus COL SIS domain-containing protein YP_185503.1 650992 D 93062 CDS YP_185504.1 57651448 3236744 651644..652300 1 NC_002951.2 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; HAD superfamily hydrolase 652300 3236744 SACOL0619 Staphylococcus aureus subsp. aureus COL HAD superfamily hydrolase YP_185504.1 651644 D 93062 CDS YP_185505.1 57651449 3238378 652802..654202 1 NC_002951.2 identified by similarity to EGAD:8124; match to protein family HMM PF00083; match to protein family HMM PF07690; osmoprotectant proline transporter 654202 proP 3238378 proP Staphylococcus aureus subsp. aureus COL osmoprotectant proline transporter YP_185505.1 652802 D 93062 CDS YP_185506.1 57651450 3238379 654746..656122 1 NC_002951.2 identified by match to protein family HMM PF00501; substrate--CoA ligase 656122 3238379 SACOL0621 Staphylococcus aureus subsp. aureus COL substrate--CoA ligase YP_185506.1 654746 D 93062 CDS YP_185507.1 57651451 3238380 656124..657263 1 NC_002951.2 identified by similarity to EGAD:91218; similarity to EGAD:173607; match to protein family HMM PF00108; match to protein family HMM PF02803; match to protein family HMM TIGR01930; acetyl-CoA acetyltransferase 657263 atoB 3238380 atoB Staphylococcus aureus subsp. aureus COL acetyl-CoA acetyltransferase YP_185507.1 656124 D 93062 CDS YP_185508.1 57651452 3238381 657238..657603 1 NC_002951.2 hypothetical protein 657603 3238381 SACOL0623 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185508.1 657238 D 93062 CDS YP_185509.1 57651453 3238382 657606..657875 1 NC_002951.2 identified by similarity to GB:AAO03945.1; hypothetical protein 657875 3238382 SACOL0624 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185509.1 657606 D 93062 CDS YP_185510.1 57651454 3238383 complement(658076..658243) 1 NC_002951.2 hypothetical protein 658243 3238383 SACOL0625 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185510.1 658076 R 93062 CDS YP_185511.1 57651455 3238551 complement(658750..659580) 1 NC_002951.2 identified by similarity to EGAD:21177; match to protein family HMM TIGR00097; phosphomethylpyrimidine kinase 659580 thiD1 3238551 thiD1 Staphylococcus aureus subsp. aureus COL phosphomethylpyrimidine kinase YP_185511.1 658750 R 93062 CDS YP_185512.1 57651456 3238552 659764..660420 1 NC_002951.2 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 660420 ung 3238552 ung Staphylococcus aureus subsp. aureus COL uracil-DNA glycosylase YP_185512.1 659764 D 93062 CDS YP_185513.1 57651457 3238553 660421..660801 1 NC_002951.2 identified by similarity to GB:AAO03949.1; hypothetical protein 660801 3238553 SACOL0628 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185513.1 660421 D 93062 CDS YP_185514.1 57651458 3238554 660934..661302 1 NC_002951.2 identified by similarity to EGAD:17353; match to protein family HMM PF04241; hypothetical protein 661302 3238554 SACOL0629 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185514.1 660934 D 93062 CDS YP_185515.1 57651459 3238555 661423..662907 1 NC_002951.2 identified by match to protein family HMM PF00324; amino acid permease 662907 3238555 SACOL0630 Staphylococcus aureus subsp. aureus COL amino acid permease YP_185515.1 661423 D 93062 CDS YP_185516.1 57651460 3238421 complement(663049..663501) 1 NC_002951.2 identified by similarity to GP:10172694; hypothetical protein 663501 3238421 SACOL0631 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185516.1 663049 R 93062 CDS YP_185517.1 57651461 3238422 complement(663514..664278) 1 NC_002951.2 identified by match to protein family HMM PF06738; hypothetical protein 664278 3238422 SACOL0632 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185517.1 663514 R 93062 CDS YP_185518.1 57651462 3238423 complement(664827..665579) 1 NC_002951.2 identified by similarity to EGAD:20638; match to protein family HMM PF06778; heme peroxidase 665579 3238423 SACOL0633 Staphylococcus aureus subsp. aureus COL heme peroxidase YP_185518.1 664827 R 93062 CDS YP_185519.1 57651463 3238424 665747..666733 1 NC_002951.2 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 666733 eutD 3238424 eutD Staphylococcus aureus subsp. aureus COL phosphotransacetylase YP_185519.1 665747 D 93062 CDS YP_185520.1 57651464 3238425 666736..667572 1 NC_002951.2 lipoate-protein ligase A family protein 667572 3238425 SACOL0635 Staphylococcus aureus subsp. aureus COL lipoate-protein ligase A family protein YP_185520.1 666736 D 93062 CDS YP_185521.1 57651465 3238171 668159..669079 1 NC_002951.2 identified by similarity to GP:9937364; match to protein family HMM PF00288; match to protein family HMM TIGR00549; mevalonate kinase 669079 mvk 3238171 mvk Staphylococcus aureus subsp. aureus COL mevalonate kinase YP_185521.1 668159 D 93062 CDS YP_185522.1 57651466 3238172 669084..670067 1 NC_002951.2 identified by similarity to GP:14246359; match to protein family HMM PF00288; match to protein family HMM TIGR01240; mevalonate diphosphate decarboxylase 670067 mvaD 3238172 mvaD Staphylococcus aureus subsp. aureus COL mevalonate diphosphate decarboxylase YP_185522.1 669084 D 93062 CDS YP_185523.1 57650049 3238051 670080..671156 1 NC_002951.2 identified by match to protein family HMM PF00288; match to protein family HMM TIGR01220; phosphomevalonate kinase 671156 3238051 SACOL0638 Staphylococcus aureus subsp. aureus COL phosphomevalonate kinase YP_185523.1 670080 D 93062 CDS YP_185524.1 57650050 3238519 671333..671674 1 NC_002951.2 identified by similarity to GP:10176446; hypothetical protein 671674 3238519 SACOL0639 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185524.1 671333 D 93062 CDS YP_185525.1 57650051 3238584 complement(671727..673049) 1 NC_002951.2 identified by match to protein family HMM PF00070; match to protein family HMM PF02852; pyridine nucleotide-disulfide oxidoreductase 673049 3238584 SACOL0640 Staphylococcus aureus subsp. aureus COL pyridine nucleotide-disulfide oxidoreductase YP_185525.1 671727 R 93062 CDS YP_185526.1 57650052 3238415 complement(673036..673476) 1 NC_002951.2 identified by similarity to GP:4512355; hypothetical protein 673476 3238415 SACOL0641 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185526.1 673036 R 93062 CDS YP_185527.1 57650053 3238266 673534..673635 1 NC_002951.2 hypothetical protein 673635 3238266 SACOL0642 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185527.1 673534 D 93062 CDS YP_185528.1 57650054 3238138 674101..675510 1 NC_002951.2 identified by similarity to GP:11230708; hypothetical protein 675510 3238138 SACOL0643 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185528.1 674101 D 93062 CDS YP_185529.1 57650055 3238516 675514..676140 1 NC_002951.2 identified by similarity to GP:11230710; match to protein family HMM PF04276; match to protein family HMM TIGR01218; hypothetical protein 676140 3238516 SACOL0644 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185529.1 675514 D 93062 CDS YP_185530.1 57650056 3238034 676266..676907 1 NC_002951.2 identified by similarity to GP:11230710; match to protein family HMM PF04276; match to protein family HMM TIGR01218; hypothetical protein 676907 3238034 SACOL0645 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185530.1 676266 D 93062 CDS YP_185531.1 57650057 3238390 676995..677612 1 NC_002951.2 identified by similarity to GP:11230710; match to protein family HMM PF04276; match to protein family HMM TIGR01218; hypothetical protein 677612 3238390 SACOL0646 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185531.1 676995 D 93062 CDS YP_185532.1 57650058 3238593 677687..678316 1 NC_002951.2 identified by similarity to GP:11230710; match to protein family HMM PF04276; match to protein family HMM TIGR01218; hypothetical protein 678316 3238593 SACOL0647 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185532.1 677687 D 93062 CDS YP_185533.1 57650059 3238000 678512..679132 1 NC_002951.2 identified by similarity to GP:11230710; match to protein family HMM PF04276; match to protein family HMM TIGR01218; hypothetical protein 679132 3238000 SACOL0648 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185533.1 678512 D 93062 CDS YP_185534.1 57650060 3238566 679263..679904 1 NC_002951.2 identified by similarity to GP:11230710; match to protein family HMM PF04276; match to protein family HMM TIGR01218; hypothetical protein 679904 3238566 SACOL0649 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185534.1 679263 D 93062 CDS YP_185535.1 57650061 3238495 679951..680580 1 NC_002951.2 identified by similarity to GP:11230710; match to protein family HMM PF04276; match to protein family HMM TIGR01218; hypothetical protein 680580 3238495 SACOL0650 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185535.1 679951 D 93062 CDS YP_185536.1 57650062 3238419 681033..681662 1 NC_002951.2 identified by similarity to GP:11230710; match to protein family HMM PF04276; match to protein family HMM TIGR01218; hypothetical protein 681662 3238419 SACOL0651 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185536.1 681033 D 93062 CDS YP_185537.1 57650063 3238250 681777..682427 1 NC_002951.2 identified by similarity to GP:11230710; match to protein family HMM PF04276; match to protein family HMM TIGR01218; hypothetical protein 682427 3238250 SACOL0652 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185537.1 681777 D 93062 CDS YP_185538.1 57650064 3238177 682464..683099 1 NC_002951.2 identified by similarity to GP:10173594; match to protein family HMM PF04276; match to protein family HMM TIGR01218; hypothetical protein 683099 3238177 SACOL0653 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185538.1 682464 D 93062 CDS YP_185539.1 57650065 3238201 683334..683960 1 NC_002951.2 identified by similarity to GP:11230710; match to protein family HMM PF04276; match to protein family HMM TIGR01218; hypothetical protein 683960 3238201 SACOL0654 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185539.1 683334 D 93062 CDS YP_185540.1 57650066 3238144 684230..685168 1 NC_002951.2 identified by similarity to EGAD:30452; match to protein family HMM PF00248; aldo/keto reductase oxidoreductase 685168 3238144 SACOL0655 Staphylococcus aureus subsp. aureus COL aldo/keto reductase oxidoreductase YP_185540.1 684230 D 93062 CDS YP_185541.1 57650067 3238186 685379..685915 1 NC_002951.2 identified by similarity to EGAD:107983; hypothetical protein 685915 3238186 SACOL0656 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185541.1 685379 D 93062 CDS YP_185542.1 57650068 3238558 686600..687895 1 NC_002951.2 identified by match to protein family HMM PF01966; HD domain-containing protein 687895 3238558 SACOL0658 Staphylococcus aureus subsp. aureus COL HD domain-containing protein YP_185542.1 686600 D 93062 CDS YP_185543.1 57650069 3238192 687923..688444 1 NC_002951.2 identified by similarity to EGAD:108331; hypothetical protein 688444 3238192 SACOL0659 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185543.1 687923 D 93062 CDS YP_185544.1 57650070 3238251 688943..689953 1 NC_002951.2 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 689953 adhP 3238251 adhP Staphylococcus aureus subsp. aureus COL alcohol dehydrogenase YP_185544.1 688943 D 93062 CDS YP_185545.1 57650071 3238121 690028..690135 1 NC_002951.2 hypothetical protein 690135 3238121 SACOL0661 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185545.1 690028 D 93062 CDS YP_185546.1 57650072 3238233 690216..690644 1 NC_002951.2 identified by similarity to EGAD:108312; hypothetical protein 690644 3238233 SACOL0662 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185546.1 690216 D 93062 CDS YP_185547.1 57650073 3238408 690641..692302 1 NC_002951.2 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 692302 argS 3238408 argS Staphylococcus aureus subsp. aureus COL arginyl-tRNA synthetase YP_185547.1 690641 D 93062 CDS YP_185548.1 57650074 3238050 692691..693326 1 NC_002951.2 identified by match to protein family HMM PF00730; endonuclease III 693326 3238050 SACOL0664 Staphylococcus aureus subsp. aureus COL endonuclease III YP_185548.1 692691 D 93062 CDS YP_185549.1 57650075 3238565 693705..694592 1 NC_002951.2 identified by match to protein family HMM PF01497; iron compound ABC transporter iron compound-binding protein 694592 3238565 SACOL0665 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter iron compound-binding protein YP_185549.1 693705 D 93062 CDS YP_185550.1 57650076 3238642 694740..695690 1 NC_002951.2 identified by match to protein family HMM PF01032; iron compound ABC transporter permease 695690 3238642 SACOL0666 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter permease YP_185550.1 694740 D 93062 CDS YP_185551.1 57650077 3238498 695745..696464 1 NC_002951.2 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; HAD superfamily hydrolase 696464 3238498 SACOL0667 Staphylococcus aureus subsp. aureus COL HAD superfamily hydrolase YP_185551.1 695745 D 93062 CDS YP_185552.1 57650078 3238412 696448..697248 1 NC_002951.2 identified by match to protein family HMM PF00561; alpha/beta fold family hydrolase 697248 3238412 SACOL0668 Staphylococcus aureus subsp. aureus COL alpha/beta fold family hydrolase YP_185552.1 696448 D 93062 CDS YP_185553.1 57650079 3238294 697384..697890 1 NC_002951.2 identified by similarity to GB:AAO03984.1; hypothetical protein 697890 3238294 SACOL0669 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185553.1 697384 D 93062 CDS YP_185554.1 57650080 3238411 698052..698768 1 NC_002951.2 identified by similarity to GB:AAO03985.1; hypothetical protein 698768 3238411 SACOL0670 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185554.1 698052 D 93062 CDS YP_185555.1 57650081 3238544 698937..699725 1 NC_002951.2 identified by match to protein family HMM PF00561; alpha/beta fold family hydrolase 699725 3238544 SACOL0671 Staphylococcus aureus subsp. aureus COL alpha/beta fold family hydrolase YP_185555.1 698937 D 93062 CDS YP_185556.1 57650082 3238478 complement(699976..700350) 1 NC_002951.2 identified by similarity to EGAD:42500; match to protein family HMM TIGR01889; accessory regulator A 700350 sarA 3238478 sarA Staphylococcus aureus subsp. aureus COL accessory regulator A YP_185556.1 699976 R 93062 CDS YP_185557.1 57651380 3237116 complement(700498..700617) 1 NC_002951.2 hypothetical protein 700617 3237116 SACOL0673 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185557.1 700498 R 93062 CDS YP_185558.1 57650083 3238003 complement(701298..702191) 1 NC_002951.2 identified by similarity to GB:AAO03989.1; match to protein family HMM PF04657; hypothetical protein 702191 3238003 SACOL0675 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185558.1 701298 R 93062 CDS YP_185559.1 57650084 3238289 complement(702422..702646) 1 NC_002951.2 identified by similarity to GB:AAO03992.1; hypothetical protein 702646 3238289 SACOL0676 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185559.1 702422 R 93062 CDS YP_185560.1 57650085 3238594 complement(702663..702866) 1 NC_002951.2 identified by similarity to GB:AAO03993.1; hypothetical protein 702866 3238594 SACOL0677 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185560.1 702663 R 93062 CDS YP_185561.1 57650086 3238465 703025..703585 1 NC_002951.2 identified by similarity to EGAD:9824; match to protein family HMM PF00589; phage integrase integrase/recombinase 703585 3238465 SACOL0678 Staphylococcus aureus subsp. aureus COL phage integrase integrase/recombinase YP_185561.1 703025 D 93062 CDS YP_185562.1 57650087 3237886 703604..706006 1 NC_002951.2 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit A 706006 3237886 SACOL0679 Staphylococcus aureus subsp. aureus COL monovalent cation/H+ antiporter subunit A YP_185562.1 703604 D 93062 CDS YP_185563.1 57650088 3237831 705993..706418 1 NC_002951.2 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit B 706418 3237831 SACOL0680 Staphylococcus aureus subsp. aureus COL monovalent cation/H+ antiporter subunit B YP_185563.1 705993 D 93062 CDS YP_185564.1 57650089 3237268 706415..706759 1 NC_002951.2 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit C 706759 3237268 SACOL0681 Staphylococcus aureus subsp. aureus COL monovalent cation/H+ antiporter subunit C YP_185564.1 706415 D 93062 CDS YP_185565.1 57651467 3238173 706749..708245 1 NC_002951.2 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; in S. meliloti it is known to be involved specifically with K+ transport; monovalent cation/H+ antiporter subunit D 708245 3238173 SACOL0682 Staphylococcus aureus subsp. aureus COL monovalent cation/H+ antiporter subunit D YP_185565.1 706749 D 93062 CDS YP_185566.1 57651468 3238174 708246..708728 1 NC_002951.2 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; monovalent cation/H+ antiporter subunit E 708728 3238174 SACOL0684 Staphylococcus aureus subsp. aureus COL monovalent cation/H+ antiporter subunit E YP_185566.1 708246 D 93062 CDS YP_185567.1 57651469 3238175 708725..709027 1 NC_002951.2 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit F 709027 3238175 SACOL0685 Staphylococcus aureus subsp. aureus COL monovalent cation/H+ antiporter subunit F YP_185567.1 708725 D 93062 CDS YP_185568.1 57651470 3238176 709002..709439 1 NC_002951.2 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit G 709439 3238176 SACOL0686 Staphylococcus aureus subsp. aureus COL monovalent cation/H+ antiporter subunit G YP_185568.1 709002 D 93062 CDS YP_185569.1 57651471 3236720 709779..711821 1 NC_002951.2 identified by match to protein family HMM PF00999; Na+/H+ antiporter 711821 3236720 SACOL0687 Staphylococcus aureus subsp. aureus COL Na+/H+ antiporter YP_185569.1 709779 D 93062 CDS YP_185570.1 57651472 3236721 complement(712981..713910) 1 NC_002951.2 identified by match to protein family HMM PF01297; ABC transporter substrate-binding protein 713910 3236721 SACOL0688 Staphylococcus aureus subsp. aureus COL ABC transporter substrate-binding protein YP_185570.1 712981 R 93062 CDS YP_185571.1 57651473 3236722 complement(713907..714743) 1 NC_002951.2 identified by match to protein family HMM PF00950; ABC transporter permease 714743 3236722 SACOL0689 Staphylococcus aureus subsp. aureus COL ABC transporter permease YP_185571.1 713907 R 93062 CDS YP_185572.1 57651474 3236723 complement(714737..715480) 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 715480 3236723 SACOL0690 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_185572.1 714737 R 93062 CDS YP_185573.1 57651475 3236724 715602..716246 1 NC_002951.2 identified by similarity to GP:1617434; match to protein family HMM PF01325; match to protein family HMM PF02742; match to protein family HMM PF04023; iron-dependent repressor 716246 sirR 3236724 sirR Staphylococcus aureus subsp. aureus COL iron-dependent repressor YP_185573.1 715602 D 93062 CDS YP_185574.1 57651476 3236582 complement(716326..717078) 1 NC_002951.2 identified by similarity to GB:AAO04006.1; hypothetical protein 717078 3236582 SACOL0692 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185574.1 716326 R 93062 CDS YP_185575.1 57651477 3236583 717314..718078 1 NC_002951.2 identified by similarity to EGAD:19699; match to protein family HMM PF03808; match to protein family HMM TIGR00696; teichoic acid biosynthesis protein 718078 tagA 3236583 tagA Staphylococcus aureus subsp. aureus COL teichoic acid biosynthesis protein YP_185575.1 717314 D 93062 CDS YP_185576.1 57651478 3236584 complement(718139..718933) 1 NC_002951.2 with TagG is involved in the export of teichoic acids; teichoic acids export protein ATP-binding subunit 718933 3236584 SACOL0694 Staphylococcus aureus subsp. aureus COL teichoic acids export protein ATP-binding subunit YP_185576.1 718139 R 93062 CDS YP_185577.1 57651479 3236585 719280..720092 1 NC_002951.2 identified by similarity to EGAD:30975; match to protein family HMM PF01061; tagG protein, teichoic acid ABC transporter protein 720092 3236585 SACOL0695 Staphylococcus aureus subsp. aureus COL tagG protein, teichoic acid ABC transporter protein YP_185577.1 719280 D 93062 CDS YP_185578.1 57651480 3236586 720191..721294 1 NC_002951.2 identified by similarity to EGAD:16235; match to protein family HMM PF04464; teichoic acid biosynthesis protein B 721294 tagB 3236586 tagB Staphylococcus aureus subsp. aureus COL teichoic acid biosynthesis protein B YP_185578.1 720191 D 93062 CDS YP_185579.1 57651481 3236587 721291..722352 1 NC_002951.2 identified by similarity to GP:1913906; match to protein family HMM PF00535; teichoic acid biosynthesis protein X 722352 tagX 3236587 tagX Staphylococcus aureus subsp. aureus COL teichoic acid biosynthesis protein X YP_185579.1 721291 D 93062 CDS YP_185580.1 57651482 3236188 722415..722813 1 NC_002951.2 identified by similarity to EGAD:16695; match to protein family HMM PF01467; match to protein family HMM TIGR00125; match to protein family HMM TIGR01518; glycerol-3-phosphate cytidylyltransferase 722813 tagD 3236188 tagD Staphylococcus aureus subsp. aureus COL glycerol-3-phosphate cytidylyltransferase YP_185580.1 722415 D 93062 CDS YP_185581.1 57651483 3236189 complement(722930..724225) 1 NC_002951.2 identified by match to protein family HMM PF00144; match to protein family HMM PF00768; penicillin-binding protein 4 724225 pbp4 3236189 pbp4 Staphylococcus aureus subsp. aureus COL penicillin-binding protein 4 YP_185581.1 722930 R 93062 CDS YP_185582.1 57651484 3236190 724646..726373 1 NC_002951.2 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 726373 abcA 3236190 abcA Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein/permease YP_185582.1 724646 D 93062 CDS YP_185583.1 57651485 3236191 726732..727961 1 NC_002951.2 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; nucleoside permease NupC 727961 3236191 SACOL0701 Staphylococcus aureus subsp. aureus COL nucleoside permease NupC YP_185583.1 726732 D 93062 CDS YP_185584.1 57651486 3236192 728216..728308 1 NC_002951.2 hypothetical protein 728308 3236192 SACOL0702 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185584.1 728216 D 93062 CDS YP_185585.1 57651487 3236240 728486..729319 1 NC_002951.2 identified by similarity to EGAD:108622; match to protein family HMM PF02588; hypothetical protein 729319 3236240 SACOL0703 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185585.1 728486 D 93062 CDS YP_185586.1 57651488 3236241 729601..730398 1 NC_002951.2 identified by similarity to EGAD:37683; match to protein family HMM PF00005; iron compound ABC transporter ATP-binding protein 730398 3236241 SACOL0704 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter ATP-binding protein YP_185586.1 729601 D 93062 CDS YP_185587.1 57651489 3236242 730434..731438 1 NC_002951.2 identified by similarity to EGAD:23253; match to protein family HMM PF01032; iron compound ABC transporter permease 731438 3236242 SACOL0705 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter permease YP_185587.1 730434 D 93062 CDS YP_185588.1 57651490 3236243 731435..732451 1 NC_002951.2 identified by similarity to EGAD:37682; match to protein family HMM PF01032; iron compound ABC transporter permease 732451 3236243 SACOL0706 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter permease YP_185588.1 731435 D 93062 CDS YP_185589.1 57651491 3236244 732688..733653 1 NC_002951.2 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 733653 3236244 SACOL0707 Staphylococcus aureus subsp. aureus COL dihydroxyacetone kinase subunit DhaK YP_185589.1 732688 D 93062 CDS YP_185590.1 57651492 3236603 733695..734279 1 NC_002951.2 identified by similarity to OMNI:NTL01BH3400; match to protein family HMM PF02734; match to protein family HMM TIGR02365; DAK2 domain-containing protein 734279 3236603 SACOL0708 Staphylococcus aureus subsp. aureus COL DAK2 domain-containing protein YP_185590.1 733695 D 93062 CDS YP_185591.1 57651493 3236604 734272..734634 1 NC_002951.2 identified by similarity to OMNI:NTL01LL0257; match to protein family HMM PF03610; match to protein family HMM TIGR02364; phosphotransferase mannnose-specific family component IIA 734634 3236604 SACOL0709 Staphylococcus aureus subsp. aureus COL phosphotransferase mannnose-specific family component IIA YP_185591.1 734272 D 93062 CDS YP_185592.1 57651494 3236605 734750..735247 1 NC_002951.2 identified by similarity to OMNI:SA0710; hypothetical protein 735247 3236605 SACOL0710 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185592.1 734750 D 93062 CDS YP_185593.1 57651495 3236606 735703..736770 1 NC_002951.2 identified by similarity to EGAD:107607; match to protein family HMM PF05525; hypothetical protein 736770 3236606 SACOL0711 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185593.1 735703 D 93062 CDS YP_185594.1 57651496 3236607 736921..737964 1 NC_002951.2 lipase/esterase 737964 3236607 SACOL0712 Staphylococcus aureus subsp. aureus COL lipase/esterase YP_185594.1 736921 D 93062 CDS YP_185595.1 57651497 3236608 738293..738721 1 NC_002951.2 hypothetical protein 738721 3236608 SACOL0713 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185595.1 738293 D 93062 CDS YP_185596.1 57651498 3236595 complement(738930..739436) 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 739436 3236595 SACOL0714 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_185596.1 738930 R 93062 CDS YP_185597.1 57651499 3236596 739549..740472 1 NC_002951.2 identified by similarity to GB:AAO04023.1; hypothetical protein 740472 3236596 SACOL0715 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185597.1 739549 D 93062 CDS YP_185598.1 57651500 3236597 740479..741162 1 NC_002951.2 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 741162 3236597 SACOL0716 Staphylococcus aureus subsp. aureus COL DNA-binding response regulator YP_185598.1 740479 D 93062 CDS YP_185599.1 57651501 3236598 741155..742195 1 NC_002951.2 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 742195 3236598 SACOL0717 Staphylococcus aureus subsp. aureus COL sensor histidine kinase YP_185599.1 741155 D 93062 CDS YP_185600.1 57651502 3236599 742339..743100 1 NC_002951.2 identified by similarity to EGAD:108398; match to protein family HMM PF00005; ABC transporter ATP-binding protein 743100 3236599 SACOL0718 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_185600.1 742339 D 93062 CDS YP_185601.1 57651503 3236600 743090..744979 1 NC_002951.2 ABC transporter permease 744979 3236600 SACOL0720 Staphylococcus aureus subsp. aureus COL ABC transporter permease YP_185601.1 743090 D 93062 CDS YP_185602.1 57651504 3236424 745704..746321 1 NC_002951.2 identified by match to protein family HMM PF01865; hypothetical protein 746321 3236424 SACOL0721 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185602.1 745704 D 93062 CDS YP_185603.1 57651505 3236425 746337..747344 1 NC_002951.2 identified by match to protein family HMM PF01384; phosphate transporter family protein 747344 3236425 SACOL0722 Staphylococcus aureus subsp. aureus COL phosphate transporter family protein YP_185603.1 746337 D 93062 CDS YP_185604.1 57651506 3236426 complement(747932..748729) 1 NC_002951.2 identified by match to protein family HMM PF01476; match to protein family HMM PF05257; LysM domain-containing protein 748729 3236426 SACOL0723 Staphylococcus aureus subsp. aureus COL LysM domain-containing protein YP_185604.1 747932 R 93062 CDS YP_185605.1 57651507 3236427 749090..749734 1 NC_002951.2 identified by similarity to GB:AAO04031.1; hypothetical protein 749734 3236427 SACOL0724 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185605.1 749090 D 93062 CDS YP_185606.1 57651508 3236428 750431..752581 1 NC_002951.2 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 752581 3236428 SACOL0725 Staphylococcus aureus subsp. aureus COL AraC family transcriptional regulator YP_185606.1 750431 D 93062 CDS YP_185607.1 57651509 3236429 752661..753086 1 NC_002951.2 identified by match to protein family HMM TIGR01889; hypothetical protein 753086 sarX 3236429 sarX Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185607.1 752661 D 93062 CDS YP_185608.1 57651510 3236056 753276..753992 1 NC_002951.2 identified by similarity to OMNI:NTL01BH3262; match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein 753992 3236056 SACOL0727 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185608.1 753276 D 93062 CDS YP_185609.1 57651511 3236057 753992..754465 1 NC_002951.2 identified by similarity to EGAD:48132; match to protein family HMM PF06172; hypothetical protein 754465 3236057 SACOL0728 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185609.1 753992 D 93062 CDS YP_185610.1 57651512 3236058 754818..755462 1 NC_002951.2 identified by similarity to EGAD:173390; match to protein family HMM PF04167; hypothetical protein 755462 3236058 SACOL0730 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185610.1 754818 D 93062 CDS YP_185611.1 57651513 3236059 755578..756444 1 NC_002951.2 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 756444 3236059 SACOL0731 Staphylococcus aureus subsp. aureus COL LysR family transcriptional regulator YP_185611.1 755578 D 93062 CDS YP_185612.1 57651514 3236060 756783..758003 1 NC_002951.2 identified by similarity to EGAD:19549; similarity to EGAD:173457; match to protein family HMM PF07690; sugar efflux transporter 758003 3236060 SACOL0733 Staphylococcus aureus subsp. aureus COL sugar efflux transporter YP_185612.1 756783 D 93062 CDS YP_185613.1 57651515 3238099 758000..758488 1 NC_002951.2 identified by similarity to OMNI:NTL01BH3813; match to protein family HMM PF04306; hypothetical protein 758488 3238099 SACOL0734 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185613.1 758000 D 93062 CDS YP_185614.1 57651516 3238100 complement(758587..759276) 1 NC_002951.2 identified by similarity to GB:AAO04043.1; hypothetical protein 759276 3238100 SACOL0735 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185614.1 758587 R 93062 CDS YP_185615.1 57651517 3238101 759403..759846 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 759846 3238101 SACOL0736 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_185615.1 759403 D 93062 CDS YP_185616.1 57651518 3238102 759913..760308 1 NC_002951.2 identified by similarity to GB:AAO04044.1; hypothetical protein 760308 3238102 SACOL0737 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185616.1 759913 D 93062 CDS YP_185617.1 57651519 3238103 760446..760745 1 NC_002951.2 identified by similarity to GB:AAO04045.1; hypothetical protein 760745 3238103 SACOL0738 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185617.1 760446 D 93062 CDS YP_185618.1 57651520 3238104 760825..761367 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 761367 3238104 SACOL0739 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_185618.1 760825 D 93062 CDS YP_185619.1 57651521 3237145 complement(761463..762029) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH3087; match to protein family HMM PF03641; match to protein family HMM TIGR00730; hypothetical protein 762029 3237145 SACOL0740 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185619.1 761463 R 93062 CDS YP_185620.1 57651522 3237146 complement(762031..762489) 1 NC_002951.2 identified by similarity to EGAD:42455; match to protein family HMM PF02639; hypothetical protein 762489 3237146 SACOL0741 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185620.1 762031 R 93062 CDS YP_185621.1 57651523 3237147 complement(762492..763175) 1 NC_002951.2 hypothetical protein 763175 3237147 SACOL0742 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185621.1 762492 R 93062 CDS YP_185622.1 57651524 3237148 complement(763347..764222) 1 NC_002951.2 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters UDP disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 764222 uppP 3237148 uppP Staphylococcus aureus subsp. aureus COL UDP pyrophosphate phosphatase YP_185622.1 763347 R 93062 CDS YP_185623.1 57651525 3237149 764441..766072 1 NC_002951.2 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein 766072 3237149 SACOL0744 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_185623.1 764441 D 93062 CDS YP_185624.1 57651526 3237854 766069..767742 1 NC_002951.2 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein 767742 3237854 SACOL0745 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_185624.1 766069 D 93062 CDS YP_185625.1 57651527 3237855 complement(767869..768312) 1 NC_002951.2 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 768312 norR 3237855 norR Staphylococcus aureus subsp. aureus COL MarR family transcriptional regulator YP_185625.1 767869 R 93062 CDS YP_185626.1 57651528 3237856 768539..769465 1 NC_002951.2 identified by match to protein family HMM PF02492; match to protein family HMM PF07683; cobalamin synthesis protein/P47K family protein 769465 3237856 SACOL0747 Staphylococcus aureus subsp. aureus COL cobalamin synthesis protein/P47K family protein YP_185626.1 768539 D 93062 CDS YP_185627.1 57651529 3237857 769568..770476 1 NC_002951.2 identified by match to protein family HMM PF00248; aldo/keto reductase oxidoreductase 770476 3237857 SACOL0748 Staphylococcus aureus subsp. aureus COL aldo/keto reductase oxidoreductase YP_185627.1 769568 D 93062 CDS YP_185628.1 57651530 3237858 770511..770798 1 NC_002951.2 identified by similarity to GB:AAO04057.1; hypothetical protein 770798 3237858 SACOL0749 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185628.1 770511 D 93062 CDS YP_185629.1 57651531 3237859 771081..772634 1 NC_002951.2 identified by match to protein family HMM PF00939; match to protein family HMM TIGR00785; anion transporter family protein 772634 3237859 SACOL0750 Staphylococcus aureus subsp. aureus COL anion transporter family protein YP_185629.1 771081 D 93062 CDS YP_185630.1 57651532 3237789 772720..774093 1 NC_002951.2 identified by match to protein family HMM PF03441; deoxyribodipyrimidine photolyase 774093 3237789 SACOL0751 Staphylococcus aureus subsp. aureus COL deoxyribodipyrimidine photolyase YP_185630.1 772720 D 93062 CDS YP_185631.1 57651533 3237790 complement(774529..775146) 1 NC_002951.2 identified by similarity to EGAD:47605; match to protein family HMM PF07099; hypothetical protein 775146 3237790 SACOL0752 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185631.1 774529 R 93062 CDS YP_185632.1 57651534 3237791 complement(775332..775754) 1 NC_002951.2 identified by similarity to EGAD:104132; match to protein family HMM PF03479; hypothetical protein 775754 3237791 SACOL0753 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185632.1 775332 R 93062 CDS YP_185633.1 57651535 3237792 775963..777129 1 NC_002951.2 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00880; multi drug resistance protein (norA) 777129 norA 3237792 norA Staphylococcus aureus subsp. aureus COL multi drug resistance protein (norA) YP_185633.1 775963 D 93062 CDS YP_185634.1 57651536 3237793 777422..777874 1 NC_002951.2 identified by similarity to GB:AAO04064.1; hypothetical protein 777874 3237793 SACOL0755 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185634.1 777422 D 93062 CDS YP_185635.1 57651537 3237826 778048..778530 1 NC_002951.2 identified by similarity to SP:P36922; match to protein family HMM PF04073; match to protein family HMM TIGR00011; ebsC protein 778530 3237826 SACOL0756 Staphylococcus aureus subsp. aureus COL ebsC protein YP_185635.1 778048 D 93062 CDS YP_185636.1 57651538 3237827 778780..779544 1 NC_002951.2 identified by match to protein family HMM PF00455; DeoR family transcriptional regulator 779544 3237827 SACOL0757 Staphylococcus aureus subsp. aureus COL DeoR family transcriptional regulator YP_185636.1 778780 D 93062 CDS YP_185637.1 57651539 3237828 779541..780461 1 NC_002951.2 identified by similarity to GP:9501780; similarity to EGAD:107874; match to protein family HMM PF00294; 1-phosphofructokinase 780461 fruK 3237828 fruK Staphylococcus aureus subsp. aureus COL 1-phosphofructokinase YP_185637.1 779541 D 93062 CDS YP_185638.1 57651540 3237830 782732..783913 1 NC_002951.2 identified by similarity to EGAD:107401; match to protein family HMM PF01979; match to protein family HMM TIGR00221; N-acetylglucosamine-6-phosphate deacetylase 783913 nagA 3237830 nagA Staphylococcus aureus subsp. aureus COL N-acetylglucosamine-6-phosphate deacetylase YP_185638.1 782732 D 93062 CDS YP_185639.1 57651541 3237796 784134..785483 1 NC_002951.2 identified by similarity to OMNI:SA0762; match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; hemolysin 785483 3237796 SACOL0762 Staphylococcus aureus subsp. aureus COL hemolysin YP_185639.1 784134 D 93062 CDS YP_185640.1 57651542 3237797 785705..786544 1 NC_002951.2 identified by match to protein family HMM PF00248; aldo/keto reductase oxidoreductase 786544 3237797 SACOL0763 Staphylococcus aureus subsp. aureus COL aldo/keto reductase oxidoreductase YP_185640.1 785705 D 93062 CDS YP_185641.1 57651543 3237798 786676..787659 1 NC_002951.2 identified by match to protein family HMM PF00535; glycosyl transferase, group 2 family protein 787659 3237798 SACOL0764 Staphylococcus aureus subsp. aureus COL glycosyl transferase, group 2 family protein YP_185641.1 786676 D 93062 CDS YP_185642.1 57651544 3237799 complement(787731..788786) 1 NC_002951.2 identified by similarity to GP:5726301; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase SaeS 788786 saeS 3237799 saeS Staphylococcus aureus subsp. aureus COL sensor histidine kinase SaeS YP_185642.1 787731 R 93062 CDS YP_185643.1 57651545 3237800 complement(788786..789472) 1 NC_002951.2 identified by similarity to GP:5726300; match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator SaeR 789472 saeR 3237800 saeR Staphylococcus aureus subsp. aureus COL DNA-binding response regulator SaeR YP_185643.1 788786 R 93062 CDS YP_185644.1 57651546 3237924 complement(789447..789920) 1 NC_002951.2 identified by similarity to GP:10174872; hypothetical protein 789920 3237924 SACOL0767 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185644.1 789447 R 93062 CDS YP_185645.1 57651547 3237925 complement(790262..790702) 1 NC_002951.2 identified by similarity to GB:AAO04078.1; hypothetical protein 790702 3237925 SACOL0768 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185645.1 790262 R 93062 CDS YP_185646.1 57651548 3237926 complement(790982..791566) 1 NC_002951.2 identified by similarity to GB:AAO04081.1; hypothetical protein 791566 3237926 SACOL0769 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185646.1 790982 R 93062 CDS YP_185647.1 57651549 3237927 complement(791665..792378) 1 NC_002951.2 identified by match to protein family HMM PF04055; radical activating enzyme family protein 792378 3237927 SACOL0770 Staphylococcus aureus subsp. aureus COL radical activating enzyme family protein YP_185647.1 791665 R 93062 CDS YP_185648.1 57651550 3237928 complement(792382..792801) 1 NC_002951.2 identified by match to protein family HMM PF01242; 6-pyruvoyl tetrahydrobiopterin synthase 792801 3237928 SACOL0771 Staphylococcus aureus subsp. aureus COL 6-pyruvoyl tetrahydrobiopterin synthase YP_185648.1 792382 R 93062 CDS YP_185649.1 57651551 3237929 complement(792803..793471) 1 NC_002951.2 identified by match to protein family HMM PF06508; match to protein family HMM TIGR00364; exsB protein 793471 3237929 SACOL0772 Staphylococcus aureus subsp. aureus COL exsB protein YP_185649.1 792803 R 93062 CDS YP_185650.1 57651552 3237801 793822..794415 1 NC_002951.2 identified by similarity to EGAD:6981; match to protein family HMM PF00117; match to protein family HMM TIGR00566; para-aminobenzoate synthase, glutamine amidotransferase, component II 794415 pabA 3237801 pabA Staphylococcus aureus subsp. aureus COL para-aminobenzoate synthase, glutamine amidotransferase, component II YP_185650.1 793822 D 93062 CDS YP_185651.1 57651553 3237803 796518..797228 1 NC_002951.2 identified by similarity to GP:10174435; match to protein family HMM PF02682; hypothetical protein 797228 3237803 SACOL0776 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185651.1 796518 D 93062 CDS YP_185652.1 57651554 3237804 797212..798216 1 NC_002951.2 identified by match to protein family HMM PF02626; hypothetical protein 798216 3237804 SACOL0777 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185652.1 797212 D 93062 CDS YP_185653.1 57651555 3237805 798690..800630 1 NC_002951.2 identified by match to protein family HMM PF00884; sulfatase 800630 3237805 SACOL0778 Staphylococcus aureus subsp. aureus COL sulfatase YP_185653.1 798690 D 93062 CDS YP_185654.1 57651556 3237783 800907..802784 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 802784 3237783 SACOL0779 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_185654.1 800907 D 93062 CDS YP_185655.1 57651557 3237784 802796..804577 1 NC_002951.2 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389; ATP-dependent DNA helicase RecQ 804577 recQ1 3237784 recQ1 Staphylococcus aureus subsp. aureus COL ATP-dependent DNA helicase RecQ YP_185655.1 802796 D 93062 CDS YP_185656.1 57651558 3237785 804799..805776 1 NC_002951.2 identified by similarity to EGAD:37691; match to protein family HMM PF00005; osmoprotectant ABC transporter ATP-binding protein 805776 3237785 SACOL0781 Staphylococcus aureus subsp. aureus COL osmoprotectant ABC transporter ATP-binding protein YP_185656.1 804799 D 93062 CDS YP_185657.1 57651559 3237786 805769..807283 1 NC_002951.2 identified by similarity to EGAD:37692; match to protein family HMM PF00528; match to protein family HMM PF04069; osmoprotectant ABC transporter permease 807283 opuBB 3237786 opuBB Staphylococcus aureus subsp. aureus COL osmoprotectant ABC transporter permease YP_185657.1 805769 D 93062 CDS YP_185658.1 57651560 3237787 807523..808581 1 NC_002951.2 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 808581 hisC 3237787 hisC Staphylococcus aureus subsp. aureus COL histidinol-phosphate aminotransferase YP_185658.1 807523 D 93062 CDS YP_185659.1 57651561 3236290 808932..809474 1 NC_002951.2 identified by similarity to EGAD:107442; match to protein family HMM PF06941; hypothetical protein 809474 3236290 SACOL0785 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185659.1 808932 D 93062 CDS YP_185660.1 57651562 3236291 809587..809748 1 NC_002951.2 hypothetical protein 809748 3236291 SACOL0786 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185660.1 809587 D 93062 CDS YP_185661.1 57651563 3236292 complement(810154..811071) 1 NC_002951.2 identified by match to protein family HMM PF00781; match to protein family HMM TIGR00147; hypothetical protein 811071 3236292 SACOL0787 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185661.1 810154 R 93062 CDS YP_185662.1 57651564 3236293 complement(811341..812846) 1 NC_002951.2 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924; proton-dependent oligopeptide transporter family protein 812846 3236293 SACOL0788 Staphylococcus aureus subsp. aureus COL proton-dependent oligopeptide transporter family protein YP_185662.1 811341 R 93062 CDS YP_185663.1 57651565 3236294 complement(813187..813687) 1 NC_002951.2 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 813687 3236294 SACOL0789 Staphylococcus aureus subsp. aureus COL 7-cyano-7-deazaguanine reductase YP_185663.1 813187 R 93062 CDS YP_185664.1 57651566 3236295 complement(813707..814573) 1 NC_002951.2 identified by match to protein family HMM PF00892; integral membrane domain-containing protein 814573 3236295 SACOL0790 Staphylococcus aureus subsp. aureus COL integral membrane domain-containing protein YP_185664.1 813707 R 93062 CDS YP_185665.1 57651383 3237119 814958..815224 1 NC_002951.2 identified by similarity to GP:14329707; ribonucleoside-diphosphate reductase 2, NrdH-redoxin 815224 3237119 SACOL0790.1 Staphylococcus aureus subsp. aureus COL ribonucleoside-diphosphate reductase 2, NrdH-redoxin YP_185665.1 814958 D 93062 CDS YP_185666.1 57651567 3237911 815374..815772 1 NC_002951.2 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 815772 nrdI 3237911 nrdI Staphylococcus aureus subsp. aureus COL ribonucleotide reductase stimulatory protein YP_185666.1 815374 D 93062 CDS YP_185667.1 57651568 3237912 815735..817840 1 NC_002951.2 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 817840 nrdE 3237912 nrdE Staphylococcus aureus subsp. aureus COL ribonucleotide-diphosphate reductase subunit alpha YP_185667.1 815735 D 93062 CDS YP_185668.1 57651569 3237913 817958..818929 1 NC_002951.2 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 818929 nrdF 3237913 nrdF Staphylococcus aureus subsp. aureus COL ribonucleotide-diphosphate reductase subunit beta YP_185668.1 817958 D 93062 CDS YP_185669.1 57651570 3237914 819062..819166 1 NC_002951.2 hypothetical protein 819166 3237914 SACOL0794 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185669.1 819062 D 93062 CDS YP_185670.1 57651571 3237915 819637..820608 1 NC_002951.2 identified by similarity to EGAD:37681; match to protein family HMM PF01032; iron compound ABC transporter permease 820608 3237915 SACOL0796 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter permease YP_185670.1 819637 D 93062 CDS YP_185671.1 57651572 3236989 820595..821551 1 NC_002951.2 identified by similarity to EGAD:37682; match to protein family HMM PF01032; iron compound ABC transporter permease 821551 3236989 SACOL0797 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter permease YP_185671.1 820595 D 93062 CDS YP_185672.1 57651573 3236990 821548..822309 1 NC_002951.2 identified by similarity to EGAD:37683; match to protein family HMM PF00005; iron compound ABC transporter ATP-binding protein 822309 3236990 SACOL0798 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter ATP-binding protein YP_185672.1 821548 D 93062 CDS YP_185673.1 57651574 3236991 822428..823456 1 NC_002951.2 identified by similarity to EGAD:22102; match to protein family HMM PF01497; transferrin receptor 823456 3236991 SACOL0799 Staphylococcus aureus subsp. aureus COL transferrin receptor YP_185673.1 822428 D 93062 CDS YP_185674.1 57651575 3236992 complement(823773..824087) 1 NC_002951.2 identified by similarity to EGAD:53989; match to protein family HMM PF05495; hypothetical protein 824087 3236992 SACOL0800 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185674.1 823773 R 93062 CDS YP_185675.1 57651576 3236993 complement(824105..825028) 1 NC_002951.2 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 825028 murB 3236993 murB Staphylococcus aureus subsp. aureus COL UDP-N-acetylenolpyruvoylglucosamine reductase YP_185675.1 824105 R 93062 CDS YP_185676.1 57651577 3236994 complement(825155..825673) 1 NC_002951.2 identified by similarity to GB:AAO04118.1; match to protein family HMM PF04229; hypothetical protein 825673 3236994 SACOL0802 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185676.1 825155 R 93062 CDS YP_185677.1 57651578 3237591 825793..826671 1 NC_002951.2 hypothetical protein 826671 3237591 SACOL0803 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185677.1 825793 D 93062 CDS YP_185678.1 57651579 3237592 826825..827145 1 NC_002951.2 identified by similarity to EGAD:30569; hypothetical protein 827145 3237592 SACOL0804 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185678.1 826825 D 93062 CDS YP_185679.1 57651580 3237593 827570..828694 1 NC_002951.2 identified by similarity to EGAD:13841; match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase 828694 3237593 SACOL0805 Staphylococcus aureus subsp. aureus COL glycerate kinase YP_185679.1 827570 D 93062 CDS YP_185680.1 57651581 3237594 complement(828883..830109) 1 NC_002951.2 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 830109 pepT 3237594 pepT Staphylococcus aureus subsp. aureus COL peptidase T YP_185680.1 828883 R 93062 CDS YP_185681.1 57651582 3237595 complement(830123..830617) 1 NC_002951.2 identified by similarity to GP:10172694; hypothetical protein 830617 3237595 SACOL0807 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185681.1 830123 R 93062 CDS YP_185682.1 57651583 3236167 complement(830635..831396) 1 NC_002951.2 identified by match to protein family HMM PF06738; hypothetical protein 831396 3236167 SACOL0808 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185682.1 830635 R 93062 CDS YP_185683.1 57651584 3236259 complement(831592..832662) 1 NC_002951.2 identified by match to protein family HMM PF00990; match to protein family HMM PF07694; match to protein family HMM TIGR00254; diguanylate cyclase 832662 3236259 SACOL0809 Staphylococcus aureus subsp. aureus COL diguanylate cyclase YP_185683.1 831592 R 93062 CDS YP_185684.1 57651585 3236260 832980..834035 1 NC_002951.2 Possible involvement in methicillin resistance.identified by similarity to EGAD:23076; match to protein family HMM PF00953; glycosyl transferase, group 4 family protein 834035 3236260 SACOL0810 Staphylococcus aureus subsp. aureus COL glycosyl transferase, group 4 family protein YP_185684.1 832980 D 93062 CDS YP_185685.1 57651586 3236261 complement(834205..834846) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH3636; match to protein family HMM PF01205; match to protein family HMM TIGR00257; hypothetical protein 834846 3236261 SACOL0811 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185685.1 834205 R 93062 CDS YP_185686.1 57651587 3236262 834990..835856 1 NC_002951.2 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; degV family protein 835856 3236262 SACOL0812 Staphylococcus aureus subsp. aureus COL degV family protein YP_185686.1 834990 D 93062 CDS YP_185687.1 57651588 3236263 836220..837302 1 NC_002951.2 identified by similarity to EGAD:24480; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851; comf operon protein 1 837302 3236263 SACOL0813 Staphylococcus aureus subsp. aureus COL comf operon protein 1 YP_185687.1 836220 D 93062 CDS YP_185688.1 57650090 3237326 837295..837969 1 NC_002951.2 identified by similarity to EGAD:11495; hypothetical protein 837969 3237326 SACOL0814 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185688.1 837295 D 93062 CDS YP_185689.1 57650091 3236329 838030..838602 1 NC_002951.2 identified by match to protein family HMM PF02482; match to protein family HMM TIGR00741; ribosomal subunit interface protein 838602 3236329 SACOL0815 Staphylococcus aureus subsp. aureus COL ribosomal subunit interface protein YP_185689.1 838030 D 93062 CDS YP_185690.1 57650092 3236839 839016..841547 1 NC_002951.2 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 841547 secA 3236839 secA Staphylococcus aureus subsp. aureus COL preprotein translocase subunit SecA YP_185690.1 839016 D 93062 CDS YP_185691.1 57650093 3237743 841589..841693 1 NC_002951.2 hypothetical protein 841693 3237743 SACOL0817 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185691.1 841589 D 93062 CDS YP_185692.1 57650094 3237992 join(841862..841933,841935..842972) 1 NC_002951.2 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 842972 prfB 3237992 prfB Staphylococcus aureus subsp. aureus COL peptide chain release factor 2 YP_185692.1 841862 D 93062 CDS YP_185693.1 57650095 3236080 843126..843233 1 NC_002951.2 hypothetical protein 843233 3236080 SACOL0819 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185693.1 843126 D 93062 CDS YP_185694.1 57650096 3237908 843381..844220 1 NC_002951.2 identified by match to protein family HMM PF01476; match to protein family HMM PF05257; LysM domain-containing protein 844220 3237908 SACOL0820 Staphylococcus aureus subsp. aureus COL LysM domain-containing protein YP_185694.1 843381 D 93062 CDS YP_185695.1 57650097 3237571 844394..845044 1 NC_002951.2 HD domain-containing protein 845044 3237571 SACOL0821 Staphylococcus aureus subsp. aureus COL HD domain-containing protein YP_185695.1 844394 D 93062 CDS YP_185696.1 57650098 3236875 845041..845277 1 NC_002951.2 identified by similarity to OMNI:NT01BS4098; hypothetical protein 845277 3236875 SACOL0822 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185696.1 845041 D 93062 CDS YP_185697.1 57650099 3237964 845540..847531 1 NC_002951.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 847531 uvrB 3237964 uvrB Staphylococcus aureus subsp. aureus COL excinuclease ABC subunit B YP_185697.1 845540 D 93062 CDS YP_185698.1 57650100 3237897 847539..850385 1 NC_002951.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 850385 uvrA 3237897 uvrA Staphylococcus aureus subsp. aureus COL excinuclease ABC subunit A YP_185698.1 847539 D 93062 CDS YP_185699.1 57650101 3237761 850992..851924 1 NC_002951.2 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 851924 hprK 3237761 hprK Staphylococcus aureus subsp. aureus COL HPr kinase/phosphorylase YP_185699.1 850992 D 93062 CDS YP_185700.1 57650102 3237753 851930..852769 1 NC_002951.2 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 852769 lgt 3237753 lgt Staphylococcus aureus subsp. aureus COL prolipoprotein diacylglyceryl transferase YP_185700.1 851930 D 93062 CDS YP_185701.1 57650103 3238318 852777..853262 1 NC_002951.2 identified by match to protein family HMM PF00132; acetyltransferase 853262 3238318 SACOL0827 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_185701.1 852777 D 93062 CDS YP_185702.1 57650104 3238466 853270..854709 1 NC_002951.2 identified by match to protein family HMM PF00515; TPR domain-containing protein 854709 3238466 SACOL0828 Staphylococcus aureus subsp. aureus COL TPR domain-containing protein YP_185702.1 853270 D 93062 CDS YP_185703.1 57650105 3238649 854776..855711 1 NC_002951.2 identified by similarity to GP:6434033; match to protein family HMM PF00070; match to protein family HMM TIGR01292; thioredoxin-disulfide reductase 855711 trxB 3238649 trxB Staphylococcus aureus subsp. aureus COL thioredoxin-disulfide reductase YP_185703.1 854776 D 93062 CDS YP_185704.1 57650106 3238109 856421..857332 1 NC_002951.2 identified by similarity to EGAD:107355; match to protein family HMM PF03668; hypothetical protein 857332 3238109 SACOL0830 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185704.1 856421 D 93062 CDS YP_185705.1 57650107 3238503 857329..858324 1 NC_002951.2 identified by similarity to GP:10176192; match to protein family HMM PF01933; match to protein family HMM TIGR01826; hypothetical protein 858324 3238503 SACOL0831 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185705.1 857329 D 93062 CDS YP_185706.1 57650108 3238205 858434..859378 1 NC_002951.2 identified by similarity to EGAD:107351; match to protein family HMM PF02650; match to protein family HMM TIGR00647; hypothetical protein 859378 3238205 SACOL0832 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185706.1 858434 D 93062 CDS YP_185707.1 57650109 3238532 859951..860538 1 NC_002951.2 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 860538 clpP 3238532 clpP Staphylococcus aureus subsp. aureus COL ATP-dependent Clp protease proteolytic subunit YP_185707.1 859951 D 93062 CDS YP_185708.1 57650110 3238107 complement(860781..861683) 1 NC_002951.2 identified by match to protein family HMM TIGR01777; hypothetical protein 861683 3238107 SACOL0834 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185708.1 860781 R 93062 CDS YP_185709.1 57650111 3238695 862387..863016 1 NC_002951.2 identified by similarity to GB:AAO04151.1; hypothetical protein 863016 3238695 SACOL0835 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185709.1 862387 D 93062 CDS YP_185710.1 57650112 3238702 complement(863205..863351) 1 NC_002951.2 hypothetical protein 863351 3238702 SACOL0836 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185710.1 863205 R 93062 CDS YP_185711.1 57650113 3238376 863776..864789 1 NC_002951.2 identified by similarity to OMNI:SA0837; match to protein family HMM PF04198; glycolytic operon regulator 864789 gapR 3238376 gapR Staphylococcus aureus subsp. aureus COL glycolytic operon regulator YP_185711.1 863776 D 93062 CDS YP_185712.1 57650114 3238183 864842..865852 1 NC_002951.2 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; glyceraldehyde 3-phosphate dehydrogenase 865852 gapA1 3238183 gapA1 Staphylococcus aureus subsp. aureus COL glyceraldehyde 3-phosphate dehydrogenase YP_185712.1 864842 D 93062 CDS YP_185713.1 57650115 3238653 865991..867181 1 NC_002951.2 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 867181 pgk 3238653 pgk Staphylococcus aureus subsp. aureus COL phosphoglycerate kinase YP_185713.1 865991 D 93062 CDS YP_185714.1 57650116 3238661 867303..868064 1 NC_002951.2 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 868064 tpiA 3238661 tpiA Staphylococcus aureus subsp. aureus COL triosephosphate isomerase YP_185714.1 867303 D 93062 CDS YP_185715.1 57650117 3238263 868067..869584 1 NC_002951.2 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 869584 pgm 3238263 pgm Staphylococcus aureus subsp. aureus COL phosphoglyceromutase YP_185715.1 868067 D 93062 CDS YP_185716.1 57650118 3238461 869714..871018 1 NC_002951.2 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 871018 eno 3238461 eno Staphylococcus aureus subsp. aureus COL phosphopyruvate hydratase YP_185716.1 869714 D 93062 CDS YP_185717.1 57650119 3238683 871358..871816 1 NC_002951.2 identified by similarity to GB:AAO04159.1; hypothetical protein 871816 3238683 SACOL0843 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185717.1 871358 D 93062 CDS YP_185718.1 57650120 3238677 871883..872116 1 NC_002951.2 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810; preprotein translocase subunit SecG 872116 secG 3238677 secG Staphylococcus aureus subsp. aureus COL preprotein translocase subunit SecG YP_185718.1 871883 D 93062 CDS YP_185719.1 57650121 3238682 872232..872972 1 NC_002951.2 identified by similarity to EGAD:18058; carboxylesterase 872972 est 3238682 est Staphylococcus aureus subsp. aureus COL carboxylesterase YP_185719.1 872232 D 93062 CDS YP_185720.1 57650122 3238592 873006..875378 1 NC_002951.2 identified by match to protein family HMM PF00575; match to protein family HMM PF00773; match to protein family HMM TIGR00358; match to protein family HMM TIGR02063; VacB/RNase II family exoribonuclease 875378 3238592 SACOL0846 Staphylococcus aureus subsp. aureus COL VacB/RNase II family exoribonuclease YP_185720.1 873006 D 93062 CDS YP_185721.1 57650123 3238583 875400..875864 1 NC_002951.2 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 875864 smpB 3238583 smpB Staphylococcus aureus subsp. aureus COL SsrA-binding protein YP_185721.1 875400 D 93062 CDS YP_185722.1 57650124 3238533 876638..876919 1 NC_002951.2 hypothetical protein 876919 3238533 SACOL0848 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185722.1 876638 D 93062 CDS YP_185723.1 57650125 3238660 complement(877186..877509) 1 NC_002951.2 hypothetical protein 877509 3238660 SACOL0849 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185723.1 877186 R 93062 CDS YP_185724.1 57650126 3238502 complement(877525..877671) 1 NC_002951.2 hypothetical protein 877671 3238502 SACOL0850 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185724.1 877525 R 93062 CDS YP_185725.1 57650127 3238317 complement(877863..878591) 1 NC_002951.2 hypothetical protein 878591 3238317 SACOL0851 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185725.1 877863 R 93062 CDS YP_185726.1 57650128 3238108 879027..879182 1 NC_002951.2 hypothetical protein 879182 3238108 SACOL0853 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185726.1 879027 D 93062 CDS YP_185727.1 57650129 3238044 879190..879711 1 NC_002951.2 hypothetical protein 879711 3238044 SACOL0854 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185727.1 879190 D 93062 CDS YP_185728.1 57650130 3238518 879850..880380 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 880380 3238518 SACOL0855 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_185728.1 879850 D 93062 CDS YP_185729.1 57650131 3238303 880643..883444 1 NC_002951.2 identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; clumping factor A 883444 clfA 3238303 clfA Staphylococcus aureus subsp. aureus COL clumping factor A YP_185729.1 880643 D 93062 CDS YP_185730.1 57650132 3238595 883665..885191 1 NC_002951.2 identified by similarity to EGAD:7465; staphylocoagulase precursor 885191 3238595 SACOL0857 Staphylococcus aureus subsp. aureus COL staphylocoagulase precursor YP_185730.1 883665 D 93062 CDS YP_185731.1 57650133 3238492 885542..886564 1 NC_002951.2 secretory extracellular matrix and plasma binding protein 886564 empbp 3238492 empbp Staphylococcus aureus subsp. aureus COL secretory extracellular matrix and plasma binding protein YP_185731.1 885542 D 93062 CDS YP_185732.1 57650134 3238290 886899..887369 1 NC_002951.2 hypothetical protein 887369 3238290 SACOL0859 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185732.1 886899 D 93062 CDS YP_185733.1 57650135 3238436 887710..888396 1 NC_002951.2 identified by similarity to EGAD:8282; match to protein family HMM PF00565; thermonuclease precursor 888396 nuc 3238436 nuc Staphylococcus aureus subsp. aureus COL thermonuclease precursor YP_185733.1 887710 D 93062 CDS YP_185734.1 57650136 3238193 888753..888953 1 NC_002951.2 identified by match to protein family HMM PF00313; CSD family cold shock protein 888953 3238193 SACOL0861 Staphylococcus aureus subsp. aureus COL CSD family cold shock protein YP_185734.1 888753 D 93062 CDS YP_185735.1 57650137 3238550 complement(889449..889667) 1 NC_002951.2 hypothetical protein 889667 3238550 SACOL0862 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185735.1 889449 R 93062 CDS YP_185736.1 57650138 3238143 complement(889729..890013) 1 NC_002951.2 identified by similarity to GB:AAO04177.1; hypothetical protein 890013 3238143 SACOL0863 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185736.1 889729 R 93062 CDS YP_185737.1 57650139 3238009 complement(890101..890670) 1 NC_002951.2 hypothetical protein 890670 3238009 SACOL0864 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185737.1 890101 R 93062 CDS YP_185738.1 57650140 3238453 complement(891075..891335) 1 NC_002951.2 hypothetical protein 891335 3238453 SACOL0865 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185738.1 891075 R 93062 CDS YP_185739.1 57650141 3238510 complement(891640..891744) 1 NC_002951.2 hypothetical protein 891744 3238510 SACOL0866 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185739.1 891640 R 93062 CDS YP_185740.1 57650142 3238199 complement(891876..892112) 1 NC_002951.2 identified by similarity to GB:AAO04183.1; hypothetical protein 892112 3238199 SACOL0868 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185740.1 891876 R 93062 CDS YP_185741.1 57650143 3238141 892328..892918 1 NC_002951.2 identified by match to protein family HMM PF00300; phosphoglycerate mutase 892918 3238141 SACOL0869 Staphylococcus aureus subsp. aureus COL phosphoglycerate mutase YP_185741.1 892328 D 93062 CDS YP_185742.1 57650144 3238020 complement(892991..893608) 1 NC_002951.2 identified by match to protein family HMM PF01810; LysE/YggA family protein 893608 3238020 SACOL0870 Staphylococcus aureus subsp. aureus COL LysE/YggA family protein YP_185742.1 892991 R 93062 CDS YP_185743.1 57650145 3238368 complement(893763..894257) 1 NC_002951.2 hypothetical protein 894257 3238368 SACOL0871 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185743.1 893763 R 93062 CDS YP_185744.1 57650146 3238279 complement(894656..895078) 1 NC_002951.2 identified by match to protein family HMM PF02566; OsmC/Ohr family protein 895078 3238279 SACOL0872 Staphylococcus aureus subsp. aureus COL OsmC/Ohr family protein YP_185744.1 894656 R 93062 CDS YP_185745.1 57650147 3238019 895226..895942 1 NC_002951.2 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 895942 aroD 3238019 aroD Staphylococcus aureus subsp. aureus COL 3-dehydroquinate dehydratase YP_185745.1 895226 D 93062 CDS YP_185746.1 57650148 3238367 896025..896564 1 NC_002951.2 identified by match to protein family HMM PF00881; nitroreductase 896564 3238367 SACOL0874 Staphylococcus aureus subsp. aureus COL nitroreductase YP_185746.1 896025 D 93062 CDS YP_185747.1 57650149 3238350 complement(896714..897034) 1 NC_002951.2 identified by match to protein family HMM PF00085; thioredoxin 897034 3238350 SACOL0875 Staphylococcus aureus subsp. aureus COL thioredoxin YP_185747.1 896714 R 93062 CDS YP_185748.1 57650150 3238606 897178..897534 1 NC_002951.2 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617; hypothetical protein 897534 3238606 SACOL0876 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185748.1 897178 D 93062 CDS YP_185749.1 57650151 3238420 897692..898072 1 NC_002951.2 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 898072 gcvH 3238420 gcvH Staphylococcus aureus subsp. aureus COL glycine cleavage system protein H YP_185749.1 897692 D 93062 CDS YP_185750.1 57650152 3238470 898251..899129 1 NC_002951.2 identified by similarity to EGAD:107990; hypothetical protein 899129 3238470 SACOL0879 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185750.1 898251 D 93062 CDS YP_185751.1 57650153 3238130 899871..900257 1 NC_002951.2 identified by match to protein family HMM PF01751; TOPRIM domain-containing protein 900257 3238130 SACOL0880 Staphylococcus aureus subsp. aureus COL TOPRIM domain-containing protein YP_185751.1 899871 D 93062 CDS YP_185752.1 57650154 3238521 900250..900546 1 NC_002951.2 hypothetical protein 900546 3238521 SACOL0881 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185752.1 900250 D 93062 CDS YP_185753.1 57650155 3238499 900796..901821 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 901821 3238499 SACOL0882 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_185753.1 900796 D 93062 CDS YP_185754.1 57650156 3238371 901814..902509 1 NC_002951.2 identified by match to protein family HMM PF00528; ABC transporter permease 902509 3238371 SACOL0883 Staphylococcus aureus subsp. aureus COL ABC transporter permease YP_185754.1 901814 D 93062 CDS YP_185755.1 57650157 3238301 902527..903348 1 NC_002951.2 identified by match to protein family HMM PF03180; ABC transporter substrate-binding protein 903348 3238301 SACOL0884 Staphylococcus aureus subsp. aureus COL ABC transporter substrate-binding protein YP_185755.1 902527 D 93062 CDS YP_185756.1 57650158 3238598 complement(903491..904711) 1 NC_002951.2 identified by similarity to EGAD:72831; match to protein family HMM PF00589; pathogenicity island protein, integrase 904711 3238598 SACOL0885 Staphylococcus aureus subsp. aureus COL pathogenicity island protein, integrase YP_185756.1 903491 R 93062 CDS YP_185757.1 57650159 3238540 complement(904800..905528) 1 NC_002951.2 identified by match to protein family HMM PF01123; match to protein family HMM PF02876; enterotoxin 905528 sek 3238540 sek Staphylococcus aureus subsp. aureus COL enterotoxin YP_185757.1 904800 R 93062 CDS YP_185758.1 57650160 3237308 complement(905552..906280) 1 NC_002951.2 identified by match to protein family HMM PF01123; match to protein family HMM PF02876; enterotoxin type I 906280 sei 3237308 sei Staphylococcus aureus subsp. aureus COL enterotoxin type I YP_185758.1 905552 R 93062 CDS YP_185759.1 57650161 3236109 complement(906350..906781) 1 NC_002951.2 pathogenicity island, lipoprotein 906781 3236109 SACOL0888 Staphylococcus aureus subsp. aureus COL pathogenicity island, lipoprotein YP_185759.1 906350 R 93062 CDS YP_185760.1 57650162 3237133 complement(906798..907256) 1 NC_002951.2 identified by similarity to GP:12697827; similarity to GP:14246619; match to protein family HMM PF06114; pathogenicity island protein 907256 3237133 SACOL0889 Staphylococcus aureus subsp. aureus COL pathogenicity island protein YP_185760.1 906798 R 93062 CDS YP_185761.1 57650163 3236162 complement(907268..907600) 1 NC_002951.2 identified by match to protein family HMM PF01381; Cro/CI family transcriptional regulator 907600 3236162 SACOL0890 Staphylococcus aureus subsp. aureus COL Cro/CI family transcriptional regulator YP_185761.1 907268 R 93062 CDS YP_185762.1 57650164 3236126 907793..908056 1 NC_002951.2 identified by match to protein family HMM PF01381; transcriptional regulator 908056 3236126 SACOL0891 Staphylococcus aureus subsp. aureus COL transcriptional regulator YP_185762.1 907793 D 93062 CDS YP_185763.1 57650165 3237883 908049..908321 1 NC_002951.2 identified by similarity to GP:2689561; pathogenicity island protein 908321 3237883 SACOL0892 Staphylococcus aureus subsp. aureus COL pathogenicity island protein YP_185763.1 908049 D 93062 CDS YP_185764.1 57650166 3237979 908333..908479 1 NC_002951.2 identified by similarity to GP:14247798; pathogenicity island protein 908479 3237979 SACOL0893 Staphylococcus aureus subsp. aureus COL pathogenicity island protein YP_185764.1 908333 D 93062 CDS YP_185765.1 57650167 3236164 908472..908681 1 NC_002951.2 identified by similarity to OMNI:NTL01SA1904; pathogenicity island protein 908681 3236164 SACOL0894 Staphylococcus aureus subsp. aureus COL pathogenicity island protein YP_185765.1 908472 D 93062 CDS YP_185766.1 57650168 3236166 908684..909004 1 NC_002951.2 identified by similarity to GP:11094390; match to protein family HMM PF07342; pathogenicity island protein 909004 3236166 SACOL0895 Staphylococcus aureus subsp. aureus COL pathogenicity island protein YP_185766.1 908684 D 93062 CDS YP_185767.1 57650169 3236165 909068..909937 1 NC_002951.2 identified by similarity to GP:11094389; pathogenicity island protein 909937 3236165 SACOL0896 Staphylococcus aureus subsp. aureus COL pathogenicity island protein YP_185767.1 909068 D 93062 CDS YP_185768.1 57650170 3237134 909954..911411 1 NC_002951.2 identified by match to protein family HMM PF05272; hypothetical protein 911411 3237134 SACOL0897 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185768.1 909954 D 93062 CDS YP_185769.1 57650171 3236093 911712..912074 1 NC_002951.2 identified by similarity to GP:11094386; pathogenicity island protein 912074 3236093 SACOL0898 Staphylococcus aureus subsp. aureus COL pathogenicity island protein YP_185769.1 911712 D 93062 CDS YP_185770.1 57651589 3237767 912076..912360 1 NC_002951.2 identified by similarity to GP:2689555; pathogenicity island protein 912360 3237767 SACOL0899 Staphylococcus aureus subsp. aureus COL pathogenicity island protein YP_185770.1 912076 D 93062 CDS YP_185771.1 57651590 3237768 912357..912998 1 NC_002951.2 identified by similarity to GP:11094385; pathogenicity island protein 912998 3237768 SACOL0900 Staphylococcus aureus subsp. aureus COL pathogenicity island protein YP_185771.1 912357 D 93062 CDS YP_185772.1 57651591 3237769 913515..913856 1 NC_002951.2 identified by similarity to GP:11094384; pathogenicity island protein 913856 3237769 SACOL0901 Staphylococcus aureus subsp. aureus COL pathogenicity island protein YP_185772.1 913515 D 93062 CDS YP_185773.1 57651592 3237770 913868..914446 1 NC_002951.2 identified by similarity to GP:2689553; pathogenicity island protein 914446 3237770 SACOL0902 Staphylococcus aureus subsp. aureus COL pathogenicity island protein YP_185773.1 913868 D 93062 CDS YP_185774.1 57651593 3237771 914464..914682 1 NC_002951.2 identified by similarity to GP:2689552; pathogenicity island protein 914682 3237771 SACOL0903 Staphylococcus aureus subsp. aureus COL pathogenicity island protein YP_185774.1 914464 D 93062 CDS YP_185775.1 57651594 3237772 914733..915260 1 NC_002951.2 identified by similarity to GP:2689551; pathogenicity island protein 915260 3237772 SACOL0904 Staphylococcus aureus subsp. aureus COL pathogenicity island protein YP_185775.1 914733 D 93062 CDS YP_185776.1 57651595 3237774 915263..915604 1 NC_002951.2 identified by similarity to GP:11094380; pathogenicity island protein 915604 3237774 SACOL0905 Staphylococcus aureus subsp. aureus COL pathogenicity island protein YP_185776.1 915263 D 93062 CDS YP_185777.1 57651596 3237775 915601..916170 1 NC_002951.2 identified by similarity to EGAD:37809; match to protein family HMM PF03592; phage terminase 916170 3237775 SACOL0906 Staphylococcus aureus subsp. aureus COL phage terminase YP_185777.1 915601 D 93062 CDS YP_185778.1 57651597 3237776 916478..917278 1 NC_002951.2 identified by similarity to GP:3212819; match to protein family HMM PF01123; match to protein family HMM PF02876; enterotoxin B 917278 seb 3237776 seb Staphylococcus aureus subsp. aureus COL enterotoxin B YP_185778.1 916478 D 93062 CDS YP_185779.1 57651598 3237777 complement(917356..917913) 1 NC_002951.2 hypothetical protein 917913 3237777 SACOL0908 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185779.1 917356 R 93062 CDS YP_185780.1 57651599 3237778 918286..918438 1 NC_002951.2 hypothetical protein 918438 3237778 SACOL0909 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185780.1 918286 D 93062 CDS YP_185781.1 57651600 3237754 918509..918619 1 NC_002951.2 hypothetical protein 918619 3237754 SACOL0910 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185781.1 918509 D 93062 CDS YP_185782.1 57651601 3237755 918606..918806 1 NC_002951.2 hypothetical protein 918806 3237755 SACOL0911 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185782.1 918606 D 93062 CDS YP_185783.1 57651602 3237756 919637..919831 1 NC_002951.2 identified by similarity to EGAD:108069; match to protein family HMM PF05532; hypothetical protein 919831 3237756 SACOL0912 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185783.1 919637 D 93062 CDS YP_185784.1 57651603 3237757 complement(920064..920915) 1 NC_002951.2 identified by similarity to GP:10174688; match to protein family HMM PF04018; hypothetical protein 920915 3237757 SACOL0913 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185784.1 920064 R 93062 CDS YP_185785.1 57651604 3237758 921243..922004 1 NC_002951.2 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978; FeS assembly ATPase SufC 922004 3237758 SACOL0914 Staphylococcus aureus subsp. aureus COL FeS assembly ATPase SufC YP_185785.1 921243 D 93062 CDS YP_185786.1 57651605 3237759 922102..923409 1 NC_002951.2 identified by similarity to EGAD:109075; match to protein family HMM PF01458; match to protein family HMM TIGR01981; FeS assembly protein SufD 923409 sufD 3237759 sufD Staphylococcus aureus subsp. aureus COL FeS assembly protein SufD YP_185786.1 922102 D 93062 CDS YP_185787.1 57651606 3237762 923524..924765 1 NC_002951.2 identified by match to protein family HMM PF00266; match to protein family HMM TIGR01979; SufS subfamily cysteine desulfurase 924765 3237762 SACOL0916 Staphylococcus aureus subsp. aureus COL SufS subfamily cysteine desulfurase YP_185787.1 923524 D 93062 CDS YP_185788.1 57651607 3237763 924755..925219 1 NC_002951.2 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994; NifU domain-containing protein 925219 3237763 SACOL0917 Staphylococcus aureus subsp. aureus COL NifU domain-containing protein YP_185788.1 924755 D 93062 CDS YP_185789.1 57651608 3237764 925370..926767 1 NC_002951.2 identified by similarity to EGAD:109032; match to protein family HMM PF01458; match to protein family HMM TIGR01980; FeS assembly protein SufB 926767 sufB 3237764 sufB Staphylococcus aureus subsp. aureus COL FeS assembly protein SufB YP_185789.1 925370 D 93062 CDS YP_185790.1 57651609 3237765 926954..927091 1 NC_002951.2 hypothetical protein 927091 3237765 SACOL0919 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185790.1 926954 D 93062 CDS YP_185791.1 57651610 3237766 complement(927097..927411) 1 NC_002951.2 hypothetical protein 927411 3237766 SACOL0920 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185791.1 927097 R 93062 CDS YP_185792.1 57651611 3237744 927776..928816 1 NC_002951.2 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; hypothetical protein 928816 3237744 SACOL0921 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185792.1 927776 D 93062 CDS YP_185793.1 57651612 3237745 928830..929897 1 NC_002951.2 identified by similarity to GP:10173821; match to protein family HMM PF03060; hypothetical protein 929897 3237745 SACOL0922 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185793.1 928830 D 93062 CDS YP_185794.1 57651613 3237746 930110..930958 1 NC_002951.2 identified by similarity to EGAD:109000; match to protein family HMM PF01904; hypothetical protein 930958 3237746 SACOL0924 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185794.1 930110 D 93062 CDS YP_185795.1 57651614 3237747 930971..931798 1 NC_002951.2 identified by similarity to GP:10176077; match to protein family HMM PF01925; hypothetical protein 931798 3237747 SACOL0925 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185795.1 930971 D 93062 CDS YP_185796.1 57651615 3237748 931825..933144 1 NC_002951.2 identified by match to protein family HMM PF00149; 5'-nucleotidase 933144 3237748 SACOL0926 Staphylococcus aureus subsp. aureus COL 5'-nucleotidase YP_185796.1 931825 D 93062 CDS YP_185797.1 57651616 3237749 933228..934145 1 NC_002951.2 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 934145 lipA 3237749 lipA Staphylococcus aureus subsp. aureus COL lipoyl synthase YP_185797.1 933228 D 93062 CDS YP_185798.1 57651617 3237898 934266..934658 1 NC_002951.2 identified by similarity to OMNI:NTL01BH3437; match to protein family HMM PF06265; hypothetical protein 934658 3237898 SACOL0928 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185798.1 934266 D 93062 CDS YP_185799.1 57651618 3237899 complement(934737..934994) 1 NC_002951.2 identified by similarity to GP:10176055; hypothetical protein 934994 3237899 SACOL0929 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185799.1 934737 R 93062 CDS YP_185800.1 57651619 3237900 935101..935535 1 NC_002951.2 identified by similarity to GP:10176053; match to protein family HMM PF01934; hypothetical protein 935535 3237900 SACOL0930 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185800.1 935101 D 93062 CDS YP_185801.1 57651620 3237901 935535..936314 1 NC_002951.2 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01457; match to protein family HMM TIGR01460; HAD superfamily hydrolase 936314 3237901 SACOL0931 Staphylococcus aureus subsp. aureus COL HAD superfamily hydrolase YP_185801.1 935535 D 93062 CDS YP_185802.1 57651621 3237902 936347..937306 1 NC_002951.2 identified by match to protein family HMM PF00389; match to protein family HMM PF02826; D-isomer specific 2-hydroxyacid dehydrogenase 937306 3237902 SACOL0932 Staphylococcus aureus subsp. aureus COL D-isomer specific 2-hydroxyacid dehydrogenase YP_185802.1 936347 D 93062 CDS YP_185803.1 57651622 3237725 937560..937670 1 NC_002951.2 hypothetical protein 937670 3237725 SACOL0933 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185803.1 937560 D 93062 CDS YP_185804.1 57651623 3237726 937718..937870 1 NC_002951.2 identified by similarity to GB:AAO04220.1; hypothetical protein 937870 3237726 SACOL0934 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185804.1 937718 D 93062 CDS YP_185805.1 57651624 3237727 937886..939343 1 NC_002951.2 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 939343 dltA 3237727 dltA Staphylococcus aureus subsp. aureus COL D-alanine--poly(phosphoribitol) ligase subunit 1 YP_185805.1 937886 D 93062 CDS YP_185806.1 57651625 3237728 939340..940554 1 NC_002951.2 identified by similarity to EGAD:22430; match to protein family HMM PF03062; DltB protein 940554 dltB 3237728 dltB Staphylococcus aureus subsp. aureus COL DltB protein YP_185806.1 939340 D 93062 CDS YP_185807.1 57651626 3237729 940572..940808 1 NC_002951.2 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 940808 dltC 3237729 dltC Staphylococcus aureus subsp. aureus COL D-alanine--poly(phosphoribitol) ligase subunit 2 YP_185807.1 940572 D 93062 CDS YP_185808.1 57651627 3237730 940805..941980 1 NC_002951.2 identified by similarity to EGAD:16580; match to protein family HMM PF04914; match to protein family HMM PF04915; match to protein family HMM PF04918; DltD protein 941980 dltD 3237730 dltD Staphylococcus aureus subsp. aureus COL DltD protein YP_185808.1 940805 D 93062 CDS YP_185809.1 57651628 3237735 complement(942243..942464) 1 NC_002951.2 identified by match to protein family HMM PF01106; NifU domain-containing protein 942464 3237735 SACOL0939 Staphylococcus aureus subsp. aureus COL NifU domain-containing protein YP_185809.1 942243 R 93062 CDS YP_185810.1 57651629 3237736 942586..942909 1 NC_002951.2 identified by similarity to EGAD:108969; match to protein family HMM PF07315; hypothetical protein 942909 3237736 SACOL0940 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185810.1 942586 D 93062 CDS YP_185811.1 57651630 3237738 944349..944585 1 NC_002951.2 identified by similarity to EGAD:108965; match to protein family HMM PF07293; hypothetical protein 944585 3237738 SACOL0942 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185811.1 944349 D 93062 CDS YP_185812.1 57651631 3237739 944598..944957 1 NC_002951.2 identified by similarity to EGAD:108962; match to protein family HMM PF01521; match to protein family HMM TIGR00049; hypothetical protein 944957 3237739 SACOL0943 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185812.1 944598 D 93062 CDS YP_185813.1 57651632 3237720 945411..946619 1 NC_002951.2 identified by match to protein family HMM PF00070; NADH dehydrogenase 946619 3237720 SACOL0944 Staphylococcus aureus subsp. aureus COL NADH dehydrogenase YP_185813.1 945411 D 93062 CDS YP_185814.1 57651633 3237721 946750..948225 1 NC_002951.2 identified by similarity to EGAD:17761; match to protein family HMM PF00883; cytosol aminopeptidase 948225 3237721 SACOL0945 Staphylococcus aureus subsp. aureus COL cytosol aminopeptidase YP_185814.1 946750 D 93062 CDS YP_185815.1 57651634 3237722 948636..949952 1 NC_002951.2 identified by similarity to GP:10175982; match to protein family HMM PF03553; Na+/H+ antiporter family protein 949952 3237722 SACOL0946 Staphylococcus aureus subsp. aureus COL Na+/H+ antiporter family protein YP_185815.1 948636 D 93062 CDS YP_185816.1 57651635 3237723 949971..950345 1 NC_002951.2 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 950345 3237723 SACOL0947 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185816.1 949971 D 93062 CDS YP_185817.1 57651636 3237724 complement(950401..951555) 1 NC_002951.2 identified by similarity to GB:AAO04236.1; hypothetical protein 951555 3237724 SACOL0948 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185817.1 950401 R 93062 CDS YP_185818.1 57651637 3237710 complement(951804..952160) 1 NC_002951.2 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit G 952160 mnhG 3237710 mnhG Staphylococcus aureus subsp. aureus COL monovalent cation/H+ antiporter subunit G YP_185818.1 951804 R 93062 CDS YP_185819.1 57651638 3237711 complement(952138..952431) 1 NC_002951.2 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit F 952431 mnhF 3237711 mnhF Staphylococcus aureus subsp. aureus COL monovalent cation/H+ antiporter subunit F YP_185819.1 952138 R 93062 CDS YP_185820.1 57651639 3237712 complement(952431..952910) 1 NC_002951.2 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit E 952910 mnhE 3237712 mnhE Staphylococcus aureus subsp. aureus COL monovalent cation/H+ antiporter subunit E YP_185820.1 952431 R 93062 CDS YP_185821.1 57651640 3237713 complement(952912..954408) 1 NC_002951.2 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; monovalent cation/H+ antiporter subunit D 954408 mnhD 3237713 mnhD Staphylococcus aureus subsp. aureus COL monovalent cation/H+ antiporter subunit D YP_185821.1 952912 R 93062 CDS YP_185822.1 57651641 3237714 complement(954401..954742) 1 NC_002951.2 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit C 954742 mnhC 3237714 mnhC Staphylococcus aureus subsp. aureus COL monovalent cation/H+ antiporter subunit C YP_185822.1 954401 R 93062 CDS YP_185823.1 57651642 3237888 complement(954742..955170) 1 NC_002951.2 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in the case of S. meliloti it was proved to be involved specifically with K+ transport; monovalent cation/H+ antiporter subunit B 955170 mnhB 3237888 mnhB Staphylococcus aureus subsp. aureus COL monovalent cation/H+ antiporter subunit B YP_185823.1 954742 R 93062 CDS YP_185824.1 57651643 3237889 complement(955163..957568) 1 NC_002951.2 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit A 957568 mnhA 3237889 mnhA Staphylococcus aureus subsp. aureus COL monovalent cation/H+ antiporter subunit A YP_185824.1 955163 R 93062 CDS YP_185825.1 57651644 3237890 complement(957699..958082) 1 NC_002951.2 identified by similarity to EGAD:10092; hypothetical protein 958082 kapB 3237890 kapB Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185825.1 957699 R 93062 CDS YP_185826.1 57651645 3237891 958146..958739 1 NC_002951.2 identified by match to protein family HMM PF00160; cyclophilin type peptidyl-prolyl cis-trans isomerase 958739 3237891 SACOL0957 Staphylococcus aureus subsp. aureus COL cyclophilin type peptidyl-prolyl cis-trans isomerase YP_185826.1 958146 D 93062 CDS YP_185827.1 57651646 3237892 959155..959532 1 NC_002951.2 identified by similarity to SP:P80870; match to protein family HMM PF00575; general stress protein 13 959532 3237892 SACOL0958 Staphylococcus aureus subsp. aureus COL general stress protein 13 YP_185827.1 959155 D 93062 CDS YP_185828.1 57651647 3237696 959894..961021 1 NC_002951.2 identified by match to protein family HMM PF00724; Oye family NADH-dependent flavin oxidoreductase 961021 3237696 SACOL0959 Staphylococcus aureus subsp. aureus COL Oye family NADH-dependent flavin oxidoreductase YP_185828.1 959894 D 93062 CDS YP_185829.1 57651648 3237697 961329..962519 1 NC_002951.2 identified by similarity to EGAD:21835; match to protein family HMM PF00202; match to protein family HMM TIGR01885; ornithine--oxo-acid transaminase 962519 rocD 3237697 rocD Staphylococcus aureus subsp. aureus COL ornithine--oxo-acid transaminase YP_185829.1 961329 D 93062 CDS YP_185830.1 57651649 3237698 962628..963872 1 NC_002951.2 identified by match to protein family HMM PF00208; match to protein family HMM PF02812; glutamate dehydrogenase 963872 gluD 3237698 gluD Staphylococcus aureus subsp. aureus COL glutamate dehydrogenase YP_185830.1 962628 D 93062 CDS YP_185831.1 57651650 3237699 complement(964375..965304) 1 NC_002951.2 identified by similarity to EGAD:9350; match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase 965304 3237699 SACOL0962 Staphylococcus aureus subsp. aureus COL glycerophosphoryl diester phosphodiesterase YP_185831.1 964375 R 93062 CDS YP_185832.1 57651651 3237700 complement(965546..966925) 1 NC_002951.2 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 966925 argH 3237700 argH Staphylococcus aureus subsp. aureus COL argininosuccinate lyase YP_185832.1 965546 R 93062 CDS YP_185833.1 57651652 3237701 complement(966915..968120) 1 NC_002951.2 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 968120 argG 3237701 argG Staphylococcus aureus subsp. aureus COL argininosuccinate synthase YP_185833.1 966915 R 93062 CDS YP_185834.1 57651653 3237942 complement(968265..968399) 1 NC_002951.2 hypothetical protein 968399 3237942 SACOL0965 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185834.1 968265 R 93062 CDS YP_185835.1 57651654 3237943 968471..969802 1 NC_002951.2 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 969802 pgi 3237943 pgi Staphylococcus aureus subsp. aureus COL glucose-6-phosphate isomerase YP_185835.1 968471 D 93062 CDS YP_185836.1 57651655 3237944 970127..970702 1 NC_002951.2 identified by similarity to GP:4185300; hypothetical protein 970702 3237944 SACOL0967 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185836.1 970127 D 93062 CDS YP_185837.1 57651656 3237945 970707..971231 1 NC_002951.2 identified by similarity to SP:P72364; match to protein family HMM PF00717; match to protein family HMM TIGR02227; signal peptidase IA, inactive 971231 spsA 3237945 spsA Staphylococcus aureus subsp. aureus COL signal peptidase IA, inactive YP_185837.1 970707 D 93062 CDS YP_185838.1 57651657 3237946 971238..971822 1 NC_002951.2 identified by similarity to SP:P72365; match to protein family HMM PF00717; match to protein family HMM TIGR02227; signal peptidase IB 971822 spsB 3237946 spsB Staphylococcus aureus subsp. aureus COL signal peptidase IB YP_185838.1 971238 D 93062 CDS YP_185839.1 57651658 3237683 971982..975458 1 NC_002951.2 In Gram positive bacteria, the RexAB system appears to fulfill the biological roles of RecBCD found in Gram negative bacteria. In B. subtilis, RexAB is also known as AddABidentified by similarity to EGAD:12281; exonuclease RexB 975458 rexB 3237683 rexB Staphylococcus aureus subsp. aureus COL exonuclease RexB YP_185839.1 971982 D 93062 CDS YP_185840.1 57651659 3237684 975459..979112 1 NC_002951.2 In Gram positive bacteria, the RexAB system appears to fulfill the biological roles of RecBCD found in Gram negative bacteria. In B. subtilis, RexAB is also known as AddABidentified by similarity to EGAD:18428; match to protein family HMM PF00580; exonuclease RexA 979112 rexA 3237684 rexA Staphylococcus aureus subsp. aureus COL exonuclease RexA YP_185840.1 975459 D 93062 CDS YP_185841.1 57651660 3237685 979278..980180 1 NC_002951.2 identified by match to protein family HMM PF01557; fumarylacetoacetate hydrolase 980180 3237685 SACOL0973 Staphylococcus aureus subsp. aureus COL fumarylacetoacetate hydrolase YP_185841.1 979278 D 93062 CDS YP_185842.1 57651661 3237686 980509..980898 1 NC_002951.2 identified by similarity to EGAD:108917; match to protein family HMM PF07457; hypothetical protein 980898 3237686 SACOL0974 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185842.1 980509 D 93062 CDS YP_185843.1 57651662 3237687 complement(981069..982385) 1 NC_002951.2 NADPH-dependent; catalyzes the reduction of coenzyme A disulfide; coenzyme A disulfide reductase 982385 3237687 SACOL0975 Staphylococcus aureus subsp. aureus COL coenzyme A disulfide reductase YP_185843.1 981069 R 93062 CDS YP_185844.1 57651663 3237675 complement(982437..983261) 1 NC_002951.2 identified by match to protein family HMM PF00702; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; HAD superfamily hydrolase 983261 3237675 SACOL0976 Staphylococcus aureus subsp. aureus COL HAD superfamily hydrolase YP_185844.1 982437 R 93062 CDS YP_185845.1 57651664 3237676 983375..983683 1 NC_002951.2 identified by similarity to EGAD:107291; match to protein family HMM PF01883; hypothetical protein 983683 3237676 SACOL0977 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185845.1 983375 D 93062 CDS YP_185846.1 57651665 3237677 984230..986044 1 NC_002951.2 identified by match to protein family HMM PF01757; hypothetical protein 986044 3237677 SACOL0978 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185846.1 984230 D 93062 CDS YP_185847.1 57651666 3237678 986247..988856 1 NC_002951.2 identified by similarity to GP:5231279; match to protein family HMM PF00004; match to protein family HMM PF02861; ATP-dependent Clp protease, ATP-binding subunit ClpB 988856 clpB 3237678 clpB Staphylococcus aureus subsp. aureus COL ATP-dependent Clp protease, ATP-binding subunit ClpB YP_185847.1 986247 D 93062 CDS YP_185848.1 57651667 3237679 complement(988915..989784) 1 NC_002951.2 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 989784 3237679 SACOL0980 Staphylococcus aureus subsp. aureus COL LysR family transcriptional regulator YP_185848.1 988915 R 93062 CDS YP_185849.1 57651668 3237680 989894..991039 1 NC_002951.2 identified by similarity to EGAD:19945; match to protein family HMM PF00682; isopropylmalate synthase-like protein 991039 3237680 SACOL0981 Staphylococcus aureus subsp. aureus COL isopropylmalate synthase-like protein YP_185849.1 989894 D 93062 CDS YP_185850.1 57651669 3237875 991023..991664 1 NC_002951.2 identified by similarity to EGAD:43484; match to protein family HMM PF01300; Sua5/YciO/YrdC/YwlC family protein 991664 3237875 SACOL0982 Staphylococcus aureus subsp. aureus COL Sua5/YciO/YrdC/YwlC family protein YP_185850.1 991023 D 93062 CDS YP_185851.1 57651670 3237876 991657..992775 1 NC_002951.2 hypothetical protein 992775 3237876 SACOL0983 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185851.1 991657 D 93062 CDS YP_185852.1 57650172 3237010 992759..993274 1 NC_002951.2 identified by similarity to EGAD:108624; match to protein family HMM TIGR00481; hypothetical protein 993274 3237010 SACOL0984 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185852.1 992759 D 93062 CDS YP_185853.1 57650173 3237907 993585..994019 1 NC_002951.2 identified by match to protein family HMM PF03642; surface protein 994019 3237907 SACOL0985 Staphylococcus aureus subsp. aureus COL surface protein YP_185853.1 993585 D 93062 CDS YP_185854.1 57650174 3236154 complement(994276..994461) 1 NC_002951.2 hypothetical protein 994461 3236154 SACOL0986 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185854.1 994276 R 93062 CDS YP_185855.1 57650175 3237317 994756..995697 1 NC_002951.2 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 995697 fabH 3237317 fabH Staphylococcus aureus subsp. aureus COL 3-oxoacyl-ACP synthase YP_185855.1 994756 D 93062 CDS YP_185856.1 57650176 3237606 995709..996953 1 NC_002951.2 identified by similarity to SP:P39435; match to protein family HMM PF00109; match to protein family HMM PF02801; 3-oxoacyl-ACP synthase 996953 fabF 3237606 fabF Staphylococcus aureus subsp. aureus COL 3-oxoacyl-ACP synthase YP_185856.1 995709 D 93062 CDS YP_185857.1 57650177 3236270 complement(997008..997379) 1 NC_002951.2 identified by similarity to GB:AAO04276.1; hypothetical protein 997379 3236270 SACOL0989 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185857.1 997008 R 93062 CDS YP_185858.1 57650178 3237647 997602..997700 1 NC_002951.2 hypothetical protein 997700 3237647 SACOL0990 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185858.1 997602 D 93062 CDS YP_185859.1 57650179 3236092 997700..998548 1 NC_002951.2 identified by match to protein family HMM PF00528; oligopeptide ABC transporter permease 998548 oppB 3236092 oppB Staphylococcus aureus subsp. aureus COL oligopeptide ABC transporter permease YP_185859.1 997700 D 93062 CDS YP_185860.1 57650180 3237604 998548..999618 1 NC_002951.2 identified by match to protein family HMM PF00528; oligopeptide ABC transporter permease 999618 oppC 3237604 oppC Staphylococcus aureus subsp. aureus COL oligopeptide ABC transporter permease YP_185860.1 998548 D 93062 CDS YP_185861.1 57650181 3236193 999635..1000717 1 NC_002951.2 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01727; oligopeptide ABC transporter ATP-binding protein 1000717 oppD 3236193 oppD Staphylococcus aureus subsp. aureus COL oligopeptide ABC transporter ATP-binding protein YP_185861.1 999635 D 93062 CDS YP_185862.1 57650182 3236091 1000707..1001648 1 NC_002951.2 identified by match to protein family HMM PF00005; oligopeptide ABC transporter ATP-binding protein 1001648 oppF 3236091 oppF Staphylococcus aureus subsp. aureus COL oligopeptide ABC transporter ATP-binding protein YP_185862.1 1000707 D 93062 CDS YP_185863.1 57650183 3236268 1001666..1003321 1 NC_002951.2 identified by match to protein family HMM PF00496; oligopeptide ABC transporter oligopeptide-binding protein 1003321 3236268 SACOL0995 Staphylococcus aureus subsp. aureus COL oligopeptide ABC transporter oligopeptide-binding protein YP_185863.1 1001666 D 93062 CDS YP_185864.1 57650184 3237274 1003533..1005248 1 NC_002951.2 identified by match to protein family HMM PF00496; oligopeptide ABC transporter oligopeptide-binding protein 1005248 3237274 SACOL0996 Staphylococcus aureus subsp. aureus COL oligopeptide ABC transporter oligopeptide-binding protein YP_185864.1 1003533 D 93062 CDS YP_185865.1 57650185 3237292 1005299..1006285 1 NC_002951.2 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01727; oligopeptide ABC transporter ATP-binding protein 1006285 3237292 SACOL0997 Staphylococcus aureus subsp. aureus COL oligopeptide ABC transporter ATP-binding protein YP_185865.1 1005299 D 93062 CDS YP_185866.1 57650186 3236152 1006288..1007268 1 NC_002951.2 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01727; oligopeptide ABC transporter ATP-binding protein 1007268 3236152 SACOL0998 Staphylococcus aureus subsp. aureus COL oligopeptide ABC transporter ATP-binding protein YP_185866.1 1006288 D 93062 CDS YP_185867.1 57650187 3236083 1007261..1008223 1 NC_002951.2 identified by match to protein family HMM PF00528; oligopeptide ABC transporter permease 1008223 3236083 SACOL0999 Staphylococcus aureus subsp. aureus COL oligopeptide ABC transporter permease YP_185867.1 1007261 D 93062 CDS YP_185868.1 57650188 3236087 1008235..1009116 1 NC_002951.2 identified by match to protein family HMM PF00528; oligopeptide ABC transporter permease 1009116 3236087 SACOL1000 Staphylococcus aureus subsp. aureus COL oligopeptide ABC transporter permease YP_185868.1 1008235 D 93062 CDS YP_185869.1 57650189 3236281 complement(1009158..1010147) 1 NC_002951.2 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 1010147 trpS 3236281 trpS Staphylococcus aureus subsp. aureus COL tryptophanyl-tRNA synthetase YP_185869.1 1009158 R 93062 CDS YP_185870.1 57650190 3236118 1010442..1010837 1 NC_002951.2 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 1010837 spxA 3236118 spxA Staphylococcus aureus subsp. aureus COL transcriptional regulator Spx YP_185870.1 1010442 D 93062 CDS YP_185871.1 57650191 3237150 1011208..1011927 1 NC_002951.2 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein 1011927 3237150 SACOL1003 Staphylococcus aureus subsp. aureus COL adaptor protein YP_185871.1 1011208 D 93062 CDS YP_185872.1 57650192 3237328 1012048..1013034 1 NC_002951.2 identified by similarity to GP:3211759; match to protein family HMM PF06054; competence protein 1013034 3237328 SACOL1004 Staphylococcus aureus subsp. aureus COL competence protein YP_185872.1 1012048 D 93062 CDS YP_185873.1 57650193 3237289 1013082..1014890 1 NC_002951.2 identified by match to protein family HMM PF01432; match to protein family HMM TIGR00181; oligoendopeptidase F 1014890 pepF 3237289 pepF Staphylococcus aureus subsp. aureus COL oligoendopeptidase F YP_185873.1 1013082 D 93062 CDS YP_185874.1 57650194 3236090 complement(1015350..1016156) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH2858; hypothetical protein 1016156 3236090 SACOL1006 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185874.1 1015350 R 93062 CDS YP_185875.1 57650195 3237302 complement(1016179..1016544) 1 NC_002951.2 identified by similarity to EGAD:82734; match to protein family HMM PF01152; hypothetical protein 1016544 3237302 SACOL1007 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185875.1 1016179 R 93062 CDS YP_185876.1 57650196 3237488 complement(1016648..1017241) 1 NC_002951.2 identified by similarity to EGAD:107332; match to protein family HMM PF01928; hypothetical protein 1017241 3237488 SACOL1008 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185876.1 1016648 R 93062 CDS YP_185877.1 57650197 3237192 1017427..1017774 1 NC_002951.2 identified by similarity to OMNI:NTL01BH2853; hypothetical protein 1017774 3237192 SACOL1009 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185877.1 1017427 D 93062 CDS YP_185878.1 57650198 3236157 1017791..1018426 1 NC_002951.2 identified by match to protein family HMM PF04607; GTP pyrophosphokinase 1018426 relA1 3236157 relA1 Staphylococcus aureus subsp. aureus COL GTP pyrophosphokinase YP_185878.1 1017791 D 93062 CDS YP_185879.1 57650199 3237131 1018443..1019252 1 NC_002951.2 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1019252 ppnK 3237131 ppnK Staphylococcus aureus subsp. aureus COL inorganic polyphosphate/ATP-NAD kinase YP_185879.1 1018443 D 93062 CDS YP_185880.1 57650200 3237557 1019249..1020103 1 NC_002951.2 identified by match to protein family HMM PF00849; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase D 1020103 3237557 SACOL1012 Staphylococcus aureus subsp. aureus COL ribosomal large subunit pseudouridine synthase D YP_185880.1 1019249 D 93062 CDS YP_185881.1 57650201 3237303 1020124..1021509 1 NC_002951.2 identified by match to protein family HMM PF00571; match to protein family HMM PF01769; match to protein family HMM PF03448; match to protein family HMM TIGR00400; magnesium transporter 1021509 mgtE 3237303 mgtE Staphylococcus aureus subsp. aureus COL magnesium transporter YP_185881.1 1020124 D 93062 CDS YP_185882.1 57650202 3237502 1023641..1024411 1 NC_002951.2 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 1024411 fabI 3237502 fabI Staphylococcus aureus subsp. aureus COL enoyl-ACP reductase YP_185882.1 1023641 D 93062 CDS YP_185883.1 57650203 3236110 complement(1024606..1025691) 1 NC_002951.2 identified by similarity to GP:10175543; match to protein family HMM PF01594; hypothetical protein 1025691 3236110 SACOL1017 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185883.1 1024606 R 93062 CDS YP_185884.1 57650204 3236111 1026033..1027601 1 NC_002951.2 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; sodium:alanine symporter family protein 1027601 3236111 SACOL1018 Staphylococcus aureus subsp. aureus COL sodium:alanine symporter family protein YP_185884.1 1026033 D 93062 CDS YP_185885.1 57650205 3237282 1027743..1028501 1 NC_002951.2 identified by similarity to OMNI:NTL01BH1443; match to protein family HMM PF00756; hypothetical protein 1028501 3237282 SACOL1019 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185885.1 1027743 D 93062 CDS YP_185886.1 57650206 3237751 1028695..1029204 1 NC_002951.2 similar to 2'-5' RNA ligase; hypothetical protein 1029204 3237751 SACOL1020 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185886.1 1028695 D 93062 CDS YP_185887.1 57650207 3237297 complement(1029317..1030507) 1 NC_002951.2 identified by match to protein family HMM PF07690; hypothetical protein 1030507 3237297 SACOL1021 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185887.1 1029317 R 93062 CDS YP_185888.1 57650208 3237773 complement(1030485..1031660) 1 NC_002951.2 processive; catalyzes the formation of mono-, di- and tri-glucosyldiacylglycerol by the progressive transfer of glucosyl residues to diacylglycerol; involved in the formation of membrane glycolipids; diacylglycerol glucosyltransferase 1031660 ypfP 3237773 ypfP Staphylococcus aureus subsp. aureus COL diacylglycerol glucosyltransferase YP_185888.1 1030485 R 93062 CDS YP_185889.1 57650209 3237160 1032093..1033574 1 NC_002951.2 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase 1033574 murE 3237160 murE Staphylococcus aureus subsp. aureus COL UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase YP_185889.1 1032093 D 93062 CDS YP_185890.1 57650210 3236161 1033567..1033818 1 NC_002951.2 identified by similarity to GB:AAO04316.1; hypothetical protein 1033818 3236161 SACOL1024 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185890.1 1033567 D 93062 CDS YP_185891.1 57650211 3236280 1033818..1035380 1 NC_002951.2 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 1035380 prfC 3236280 prfC Staphylococcus aureus subsp. aureus COL peptide chain release factor 3 YP_185891.1 1033818 D 93062 CDS YP_185892.1 57650212 3237989 1035682..1036485 1 NC_002951.2 identified by similarity to GP:4160468; match to protein family HMM PF03741; hypothetical protein 1036485 3237989 SACOL1026 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185892.1 1035682 D 93062 CDS YP_185893.1 57650213 3237291 1036544..1036639 1 NC_002951.2 hypothetical protein 1036639 3237291 SACOL1027 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185893.1 1036544 D 93062 CDS YP_185894.1 57650214 3237294 1036719..1039028 1 NC_002951.2 identified by match to protein family HMM PF00089; serine protease 1039028 htrA 3237294 htrA Staphylococcus aureus subsp. aureus COL serine protease YP_185894.1 1036719 D 93062 CDS YP_185895.1 57650215 3237290 1039045..1040403 1 NC_002951.2 identified by match to protein family HMM PF02386; sodium transport family protein 1040403 3237290 SACOL1030 Staphylococcus aureus subsp. aureus COL sodium transport family protein YP_185895.1 1039045 D 93062 CDS YP_185896.1 57650216 3236160 1040542..1042053 1 NC_002951.2 identified by match to protein family HMM PF02872; 5' nucleotidase 1042053 3236160 SACOL1031 Staphylococcus aureus subsp. aureus COL 5' nucleotidase YP_185896.1 1040542 D 93062 CDS YP_185897.1 57650217 3236117 complement(1042540..1043070) 1 NC_002951.2 identified by match to protein family HMM PF06338; ComK family protein 1043070 3236117 SACOL1032 Staphylococcus aureus subsp. aureus COL ComK family protein YP_185897.1 1042540 R 93062 CDS YP_185898.1 57650218 3237577 1043319..1043537 1 NC_002951.2 hypothetical protein 1043537 3237577 SACOL1033 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185898.1 1043319 D 93062 CDS YP_185899.1 57650219 3237277 complement(1043618..1044604) 1 NC_002951.2 identified by match to protein family HMM PF03099; match to protein family HMM TIGR00545; lipoate-protein ligase A family protein 1044604 3237277 SACOL1034 Staphylococcus aureus subsp. aureus COL lipoate-protein ligase A family protein YP_185899.1 1043618 R 93062 CDS YP_185900.1 57650220 3237333 1044803..1044979 1 NC_002951.2 identified by similarity to EGAD:107617; hypothetical protein 1044979 3237333 SACOL1035 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185900.1 1044803 D 93062 CDS YP_185901.1 57650221 3237338 1044994..1045596 1 NC_002951.2 identified by match to protein family HMM PF02517; protease 1045596 3237338 SACOL1036 Staphylococcus aureus subsp. aureus COL protease YP_185901.1 1044994 D 93062 CDS YP_185902.1 57650222 3237456 1045868..1045975 1 NC_002951.2 hypothetical protein 1045975 3237456 SACOL1037 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185902.1 1045868 D 93062 CDS YP_185903.1 57650223 3236108 1046941..1048905 1 NC_002951.2 identified by match to protein family HMM TIGR01654; membrane protein 1048905 3236108 SACOL1038 Staphylococcus aureus subsp. aureus COL membrane protein YP_185903.1 1046941 D 93062 CDS YP_185904.1 57650224 3237167 1048908..1049228 1 NC_002951.2 identified by similarity to EGAD:45945; match to protein family HMM TIGR01655; hypothetical protein 1049228 3237167 SACOL1039 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185904.1 1048908 D 93062 CDS YP_185905.1 57650225 3237893 1049225..1049866 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1049866 3237893 SACOL1040 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_185905.1 1049225 D 93062 CDS YP_185906.1 57650226 3237153 complement(1049954..1050244) 1 NC_002951.2 hypothetical protein 1050244 3237153 SACOL1041 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185906.1 1049954 R 93062 CDS YP_185907.1 57650227 3236078 1050523..1050810 1 NC_002951.2 hypothetical protein 1050810 3236078 SACOL1042 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185907.1 1050523 D 93062 CDS YP_185908.1 57650228 3237331 1050816..1052297 1 NC_002951.2 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein 1052297 3237331 SACOL1043 Staphylococcus aureus subsp. aureus COL glycosyl transferase, group 1 family protein YP_185908.1 1050816 D 93062 CDS YP_185909.1 57650229 3236114 complement(1052386..1052742) 1 NC_002951.2 identified by similarity to GP:5822807; match to protein family HMM PF07681; hypothetical protein 1052742 3236114 SACOL1044 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185909.1 1052386 R 93062 CDS YP_185910.1 57650230 3236113 1053219..1054178 1 NC_002951.2 identified by match to protein family HMM PF01497; iron compound ABC transporter iron compound-binding protein 1054178 3236113 SACOL1045 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter iron compound-binding protein YP_185910.1 1053219 D 93062 CDS YP_185911.1 57650231 3236132 complement(1054224..1054355) 1 NC_002951.2 hypothetical protein 1054355 3236132 SACOL1046 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185911.1 1054224 R 93062 CDS YP_185912.1 57650232 3237055 complement(1054419..1054709) 1 NC_002951.2 identified by similarity to EGAD:47675; match to protein family HMM PF05154; hypothetical protein 1054709 3237055 SACOL1047 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185912.1 1054419 R 93062 CDS YP_185913.1 57650233 3237839 1054853..1055350 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 1055350 3237839 SACOL1048 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_185913.1 1054853 D 93062 CDS YP_185914.1 57650234 3236493 complement(1055402..1056340) 1 NC_002951.2 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 1056340 menA 3236493 menA Staphylococcus aureus subsp. aureus COL 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_185914.1 1055402 R 93062 CDS YP_185915.1 57650235 3236131 1056491..1056595 1 NC_002951.2 hypothetical protein 1056595 3236131 SACOL1050 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185915.1 1056491 D 93062 CDS YP_185916.1 57650236 3236100 1056672..1057883 1 NC_002951.2 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543; isochorismate synthase 1057883 3236100 SACOL1051 Staphylococcus aureus subsp. aureus COL isochorismate synthase YP_185916.1 1056672 D 93062 CDS YP_185917.1 57650237 3236546 1057870..1059543 1 NC_002951.2 identified by similarity to EGAD:19018; match to protein family HMM PF02776; match to protein family HMM TIGR00173; 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase 1059543 menD 3236546 menD Staphylococcus aureus subsp. aureus COL 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase YP_185917.1 1057870 D 93062 CDS YP_185918.1 57650238 3236273 1059530..1060333 1 NC_002951.2 identified by match to protein family HMM PF00561; alpha/beta fold family hydrolase 1060333 3236273 SACOL1053 Staphylococcus aureus subsp. aureus COL alpha/beta fold family hydrolase YP_185918.1 1059530 D 93062 CDS YP_185919.1 57650239 3236163 1060326..1061147 1 NC_002951.2 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 1061147 menB 3236163 menB Staphylococcus aureus subsp. aureus COL naphthoate synthase YP_185919.1 1060326 D 93062 CDS YP_185920.1 57650240 3236298 complement(1061386..1061715) 1 NC_002951.2 identified by similarity to OMNI:SA1055; sspC protein 1061715 sspC 3236298 sspC Staphylococcus aureus subsp. aureus COL sspC protein YP_185920.1 1061386 R 93062 CDS YP_185921.1 57650241 3236119 complement(1061753..1062934) 1 NC_002951.2 identified by similarity to OMNI:SA1056; match to protein family HMM PF05543; cysteine protease precursor SspB 1062934 sspB1 3236119 sspB1 Staphylococcus aureus subsp. aureus COL cysteine protease precursor SspB YP_185921.1 1061753 R 93062 CDS YP_185922.1 57650242 3237584 complement(1063016..1064026) 1 NC_002951.2 identified by similarity to EGAD:7212; match to protein family HMM PF00089; V8 protease 1064026 sspA 3237584 sspA Staphylococcus aureus subsp. aureus COL V8 protease YP_185922.1 1063016 R 93062 CDS YP_185923.1 57650243 3236079 complement(1064554..1065708) 1 NC_002951.2 identified by match to protein family HMM PF00155; aminotransferase, class I 1065708 3236079 SACOL1058 Staphylococcus aureus subsp. aureus COL aminotransferase, class I YP_185923.1 1064554 R 93062 CDS YP_185924.1 57650244 3236267 complement(1065904..1066914) 1 NC_002951.2 identified by similarity to EGAD:107562; match to protein family HMM PF01757; hypothetical protein 1066914 3236267 SACOL1059 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185924.1 1065904 R 93062 CDS YP_185925.1 57650245 3236272 1067067..1067486 1 NC_002951.2 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 1067486 3236272 SACOL1060 Staphylococcus aureus subsp. aureus COL MarR family transcriptional regulator YP_185925.1 1067067 D 93062 CDS YP_185926.1 57650246 3236133 complement(1067693..1071463) 1 NC_002951.2 identified by similarity to EGAD:42602; match to protein family HMM PF01510; match to protein family HMM PF01832; bifunctional autolysin 1071463 atl 3236133 atl Staphylococcus aureus subsp. aureus COL bifunctional autolysin YP_185926.1 1067693 R 93062 CDS YP_185927.1 57650247 3237794 complement(1071691..1072125) 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 1072125 3237794 SACOL1063 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_185927.1 1071691 R 93062 CDS YP_185928.1 57650248 3237319 complement(1072280..1072750) 1 NC_002951.2 identified by similarity to GP:2267240; hypothetical protein 1072750 3237319 SACOL1064 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185928.1 1072280 R 93062 CDS YP_185929.1 57650249 3237272 complement(1072798..1074015) 1 NC_002951.2 identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350; hypothetical protein 1074015 3237272 SACOL1065 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185929.1 1072798 R 93062 CDS YP_185930.1 57650250 3238481 1074466..1075659 1 NC_002951.2 identified by match to protein family HMM PF00144; fmt protein 1075659 3238481 SACOL1066 Staphylococcus aureus subsp. aureus COL fmt protein YP_185930.1 1074466 D 93062 CDS YP_185931.1 57650251 3238089 complement(1076196..1076474) 1 NC_002951.2 identified by match to protein family HMM PF03626; quinol oxidase subunit IV 1076474 qoxD 3238089 qoxD Staphylococcus aureus subsp. aureus COL quinol oxidase subunit IV YP_185931.1 1076196 R 93062 CDS YP_185932.1 57650252 3238140 complement(1076483..1077088) 1 NC_002951.2 identified by similarity to EGAD:6311; match to protein family HMM PF00510; quinol oxidase subunit III 1077088 qoxC 3238140 qoxC Staphylococcus aureus subsp. aureus COL quinol oxidase subunit III YP_185932.1 1076483 R 93062 CDS YP_185933.1 57650253 3238612 complement(1077078..1079066) 1 NC_002951.2 identified by similarity to EGAD:7190; match to protein family HMM PF00115; quinol oxidase subunit I 1079066 qoxA 3238612 qoxA Staphylococcus aureus subsp. aureus COL quinol oxidase subunit I YP_185933.1 1077078 R 93062 CDS YP_185934.1 57650254 3238582 complement(1079066..1080166) 1 NC_002951.2 identified by similarity to EGAD:20044; match to protein family HMM PF02790; match to protein family HMM PF06481; match to protein family HMM TIGR01432; quinol oxidase subunit II 1080166 qoxB 3238582 qoxB Staphylococcus aureus subsp. aureus COL quinol oxidase subunit II YP_185934.1 1079066 R 93062 CDS YP_185935.1 57651671 3237877 complement(1080738..1081055) 1 NC_002951.2 hypothetical protein 1081055 3237877 SACOL1071 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185935.1 1080738 R 93062 CDS YP_185936.1 57651672 3237878 complement(1081861..1082721) 1 NC_002951.2 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1082721 folD 3237878 folD Staphylococcus aureus subsp. aureus COL bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_185936.1 1081861 R 93062 CDS YP_185937.1 57651673 3237879 1082922..1083404 1 NC_002951.2 identified by similarity to EGAD:19627; match to protein family HMM PF00731; match to protein family HMM TIGR01162; phosphoribosylaminoimidazole carboxylase, catalytic subunit 1083404 purE 3237879 purE Staphylococcus aureus subsp. aureus COL phosphoribosylaminoimidazole carboxylase, catalytic subunit YP_185937.1 1082922 D 93062 CDS YP_185938.1 57651674 3237669 1083391..1084515 1 NC_002951.2 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1084515 purK 3237669 purK Staphylococcus aureus subsp. aureus COL phosphoribosylaminoimidazole carboxylase ATPase subunit YP_185938.1 1083391 D 93062 CDS YP_185939.1 57651675 3237670 1084519..1085223 1 NC_002951.2 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1085223 purC 3237670 purC Staphylococcus aureus subsp. aureus COL phosphoribosylaminoimidazole-succinocarboxamide synthase YP_185939.1 1084519 D 93062 CDS YP_185940.1 57651676 3237671 1085223..1085486 1 NC_002951.2 identified by similarity to EGAD:10915; match to protein family HMM PF02700; match to protein family HMM TIGR00302; phosphoribosylformylglycinamidine synthase, PurS protein 1085486 purS 3237671 purS Staphylococcus aureus subsp. aureus COL phosphoribosylformylglycinamidine synthase, PurS protein YP_185940.1 1085223 D 93062 CDS YP_185941.1 57651677 3237672 1085488..1086159 1 NC_002951.2 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 1086159 purQ 3237672 purQ Staphylococcus aureus subsp. aureus COL phosphoribosylformylglycinamidine synthase I YP_185941.1 1085488 D 93062 CDS YP_185942.1 57651678 3237673 1086152..1088341 1 NC_002951.2 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 1088341 purL 3237673 purL Staphylococcus aureus subsp. aureus COL phosphoribosylformylglycinamidine synthase II YP_185942.1 1086152 D 93062 CDS YP_185943.1 57651679 3236103 1088320..1089804 1 NC_002951.2 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 1089804 purF 3236103 purF Staphylococcus aureus subsp. aureus COL amidophosphoribosyltransferase YP_185943.1 1088320 D 93062 CDS YP_185944.1 57651680 3236104 1089797..1090825 1 NC_002951.2 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 1090825 purM 3236104 purM Staphylococcus aureus subsp. aureus COL phosphoribosylaminoimidazole synthetase YP_185944.1 1089797 D 93062 CDS YP_185945.1 57651681 3236105 1090828..1091394 1 NC_002951.2 identified by similarity to EGAD:16303; match to protein family HMM PF00551; match to protein family HMM TIGR00639; phosphoribosylglycinamide formyltransferase 1091394 purN 3236105 purN Staphylococcus aureus subsp. aureus COL phosphoribosylglycinamide formyltransferase YP_185945.1 1090828 D 93062 CDS YP_185946.1 57651682 3236106 1091409..1092887 1 NC_002951.2 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1092887 purH 3236106 purH Staphylococcus aureus subsp. aureus COL bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_185946.1 1091409 D 93062 CDS YP_185947.1 57651683 3236107 1092909..1094156 1 NC_002951.2 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 1094156 purD 3236107 purD Staphylococcus aureus subsp. aureus COL phosphoribosylamine--glycine ligase YP_185947.1 1092909 D 93062 CDS YP_185948.1 57651684 3237934 complement(1094421..1095227) 1 NC_002951.2 identified by match to protein family HMM PF02361; cobalt transport family protein 1095227 3237934 SACOL1084 Staphylococcus aureus subsp. aureus COL cobalt transport family protein YP_185948.1 1094421 R 93062 CDS YP_185949.1 57651685 3237935 complement(1095220..1096620) 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1096620 3237935 SACOL1085 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_185949.1 1095220 R 93062 CDS YP_185950.1 57651686 3237936 complement(1096635..1097210) 1 NC_002951.2 identified by similarity to EGAD:107484; hypothetical protein 1097210 3237936 SACOL1086 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185950.1 1096635 R 93062 CDS YP_185951.1 57651687 3237937 complement(1097857..1097991) 1 NC_002951.2 hypothetical protein 1097991 3237937 SACOL1087 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185951.1 1097857 R 93062 CDS YP_185952.1 57651688 3237938 1098143..1099438 1 NC_002951.2 identified by similarity to GB:AAO04375.1; hypothetical protein 1099438 3237938 SACOL1088 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185952.1 1098143 D 93062 CDS YP_185953.1 57651689 3237814 1099863..1101035 1 NC_002951.2 identified by similarity to EGAD:16798; hypothetical protein 1101035 3237814 SACOL1089 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185953.1 1099863 D 93062 CDS YP_185954.1 57651690 3237815 1101089..1101631 1 NC_002951.2 identified by similarity to GB:AAO04377.1; hypothetical protein 1101631 3237815 SACOL1090 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185954.1 1101089 D 93062 CDS YP_185955.1 57651691 3237816 1101785..1102051 1 NC_002951.2 identified by similarity to OMNI:SA1091; match to protein family HMM PF00381; match to protein family HMM TIGR01003; phosphocarrier protein HPr 1102051 ptsH 3237816 ptsH Staphylococcus aureus subsp. aureus COL phosphocarrier protein HPr YP_185955.1 1101785 D 93062 CDS YP_185956.1 57651692 3237817 1102054..1103772 1 NC_002951.2 identified by similarity to EGAD:13195; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417; phosphoenolpyruvate-protein phosphotransferase 1103772 ptsI 3237817 ptsI Staphylococcus aureus subsp. aureus COL phosphoenolpyruvate-protein phosphotransferase YP_185956.1 1102054 D 93062 CDS YP_185957.1 57651693 3237818 complement(1104009..1104242) 1 NC_002951.2 identified by similarity to GB:AAO04380.1; hypothetical protein 1104242 3237818 SACOL1093 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185957.1 1104009 R 93062 CDS YP_185958.1 57651694 3237819 1104440..1105801 1 NC_002951.2 identified by match to protein family HMM PF01654; cytochrome d ubiquinol oxidase subunit I 1105801 cydA 3237819 cydA Staphylococcus aureus subsp. aureus COL cytochrome d ubiquinol oxidase subunit I YP_185958.1 1104440 D 93062 CDS YP_185959.1 57651695 3237629 1105798..1106817 1 NC_002951.2 identified by similarity to GP:4514629; cytochrome d ubiquinol oxidase subunit II 1106817 cydB 3237629 cydB Staphylococcus aureus subsp. aureus COL cytochrome d ubiquinol oxidase subunit II YP_185959.1 1105798 D 93062 CDS YP_185960.1 57651696 3237630 1106950..1107612 1 NC_002951.2 identified by match to protein family HMM PF02080; match to protein family HMM PF02254; TrkA potassium uptake family protein 1107612 3237630 SACOL1096 Staphylococcus aureus subsp. aureus COL TrkA potassium uptake family protein YP_185960.1 1106950 D 93062 CDS YP_185961.1 57651697 3237631 complement(1107648..1107827) 1 NC_002951.2 hypothetical protein 1107827 3237631 SACOL1097 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185961.1 1107648 R 93062 CDS YP_185962.1 57651698 3237632 complement(1107961..1109658) 1 NC_002951.2 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; match to protein family HMM TIGR00649; hypothetical protein 1109658 3237632 SACOL1098 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185962.1 1107961 R 93062 CDS YP_185963.1 57651699 3237633 complement(1109658..1109876) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH2664; match to protein family HMM PF07288; hypothetical protein 1109876 3237633 SACOL1099 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185963.1 1109658 R 93062 CDS YP_185964.1 57651700 3237843 complement(1110357..1110908) 1 NC_002951.2 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1110908 def 3237843 def Staphylococcus aureus subsp. aureus COL peptide deformylase YP_185964.1 1110357 R 93062 CDS YP_185965.1 57651701 3237844 1111273..1111899 1 NC_002951.2 identified by similarity to SP:P21884; hypothetical protein 1111899 3237844 SACOL1101 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185965.1 1111273 D 93062 CDS YP_185966.1 57651702 3237845 1112070..1113182 1 NC_002951.2 identified by similarity to SP:P21881; match to protein family HMM PF00676; pyruvate dehydrogenase complex E1 component subunit alpha 1113182 pdhA 3237845 pdhA Staphylococcus aureus subsp. aureus COL pyruvate dehydrogenase complex E1 component subunit alpha YP_185966.1 1112070 D 93062 CDS YP_185967.1 57651703 3237846 1113186..1114163 1 NC_002951.2 identified by similarity to EGAD:13437; similarity to GP:7107452; match to protein family HMM PF02779; match to protein family HMM PF02780; pyruvate dehydrogenase complex E1 component subunit beta 1114163 pdhB 3237846 pdhB Staphylococcus aureus subsp. aureus COL pyruvate dehydrogenase complex E1 component subunit beta YP_185967.1 1113186 D 93062 CDS YP_185968.1 57651704 3237847 1114254..1115546 1 NC_002951.2 identified by similarity to EGAD:102440; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; branched-chain alpha-keto acid dehydrogenase E2 1115546 pdhC 3237847 pdhC Staphylococcus aureus subsp. aureus COL branched-chain alpha-keto acid dehydrogenase E2 YP_185968.1 1114254 D 93062 CDS YP_185969.1 57651705 3237345 1115550..1116956 1 NC_002951.2 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1116956 pdhD 3237345 pdhD Staphylococcus aureus subsp. aureus COL dihydrolipoamide dehydrogenase YP_185969.1 1115550 D 93062 CDS YP_185970.1 57651706 3237346 1117124..1117399 1 NC_002951.2 identified by similarity to OMNI:NTL01LL0557; match to protein family HMM PF05256; hypothetical protein 1117399 3237346 SACOL1106 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185970.1 1117124 D 93062 CDS YP_185971.1 57651707 3237347 1117543..1118082 1 NC_002951.2 identified by match to protein family HMM PF01381; Cro/CI family transcriptional regulator 1118082 3237347 SACOL1107 Staphylococcus aureus subsp. aureus COL Cro/CI family transcriptional regulator YP_185971.1 1117543 D 93062 CDS YP_185972.1 57651708 3237348 1118095..1119189 1 NC_002951.2 identified by match to protein family HMM PF00005; spermidine/putrescine ABC transporter ATP-binding protein 1119189 3237348 SACOL1108 Staphylococcus aureus subsp. aureus COL spermidine/putrescine ABC transporter ATP-binding protein YP_185972.1 1118095 D 93062 CDS YP_185973.1 57651709 3237349 1119182..1119979 1 NC_002951.2 identified by match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 1119979 3237349 SACOL1109 Staphylococcus aureus subsp. aureus COL spermidine/putrescine ABC transporter permease YP_185973.1 1119182 D 93062 CDS YP_185974.1 57651710 3237350 1119985..1120794 1 NC_002951.2 identified by similarity to EGAD:15490; match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 1120794 3237350 SACOL1110 Staphylococcus aureus subsp. aureus COL spermidine/putrescine ABC transporter permease YP_185974.1 1119985 D 93062 CDS YP_185975.1 57651711 3237715 1120794..1121867 1 NC_002951.2 identified by similarity to EGAD:16715; match to protein family HMM PF01547; spermidine/putrescine ABC transporter substrate-binding protein 1121867 3237715 SACOL1111 Staphylococcus aureus subsp. aureus COL spermidine/putrescine ABC transporter substrate-binding protein YP_185975.1 1120794 D 93062 CDS YP_185976.1 57651712 3237716 1121941..1122960 1 NC_002951.2 identified by similarity to GB:AAO04398.1; hypothetical protein 1122960 3237716 SACOL1112 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185976.1 1121941 D 93062 CDS YP_185977.1 57651713 3237717 1123243..1123662 1 NC_002951.2 hypothetical protein 1123662 3237717 SACOL1113 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185977.1 1123243 D 93062 CDS YP_185978.1 57651714 3237718 complement(1123744..1125096) 1 NC_002951.2 identified by match to protein family HMM PF01566; match to protein family HMM TIGR01197; manganese transport protein MntH 1125096 3237718 SACOL1114 Staphylococcus aureus subsp. aureus COL manganese transport protein MntH YP_185978.1 1123744 R 93062 CDS YP_185979.1 57651715 3237719 complement(1125280..1125894) 1 NC_002951.2 identified by similarity to EGAD:107910; match to protein family HMM PF06335; hypothetical protein 1125894 3237719 SACOL1115 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185979.1 1125280 R 93062 CDS YP_185980.1 57651716 3237981 1126051..1126878 1 NC_002951.2 identified by match to protein family HMM PF00459; inositol monophosphatase 1126878 3237981 SACOL1116 Staphylococcus aureus subsp. aureus COL inositol monophosphatase YP_185980.1 1126051 D 93062 CDS YP_185981.1 57651717 3237982 complement(1127032..1127223) 1 NC_002951.2 identified by similarity to GB:AAO04403.1; hypothetical protein 1127223 3237982 SACOL1117 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185981.1 1127032 R 93062 CDS YP_185982.1 57651718 3237983 1127325..1129172 1 NC_002951.2 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394; GTP-binding protein TypA 1129172 typA 3237983 typA Staphylococcus aureus subsp. aureus COL GTP-binding protein TypA YP_185982.1 1127325 D 93062 CDS YP_185983.1 57651719 3237984 complement(1129312..1129479) 1 NC_002951.2 identified by similarity to EGAD:107937; hypothetical protein 1129479 3237984 SACOL1119 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185983.1 1129312 R 93062 CDS YP_185984.1 57651720 3237985 complement(1129481..1129963) 1 NC_002951.2 identified by similarity to OMNI:NT01BS1746; hypothetical protein 1129963 3237985 SACOL1120 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185984.1 1129481 R 93062 CDS YP_185985.1 57651721 3237986 1130104..1130379 1 NC_002951.2 depletion of this protein in Bacillus subtilis results in defects in cell morphology; crystal structure of Staphylococcus protein shows homodimer; ligand binding protein; hypothetical protein 1130379 3237986 SACOL1121 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185985.1 1130104 D 93062 CDS YP_185986.1 57651722 3237821 1130693..1131919 1 NC_002951.2 identified by similarity to EGAD:20048; match to protein family HMM PF01098; cell cycle protein FtsW 1131919 3237821 SACOL1122 Staphylococcus aureus subsp. aureus COL cell cycle protein FtsW YP_185986.1 1130693 D 93062 CDS YP_185987.1 57651723 3237822 1132473..1135925 1 NC_002951.2 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 1135925 pyc 3237822 pyc Staphylococcus aureus subsp. aureus COL pyruvate carboxylase YP_185987.1 1132473 D 93062 CDS YP_185988.1 57651724 3237823 complement(1136065..1137135) 1 NC_002951.2 identified by similarity to EGAD:18452; match to protein family HMM PF02628; cytochrome oxidase assembly protein 1137135 ctaA 3237823 ctaA Staphylococcus aureus subsp. aureus COL cytochrome oxidase assembly protein YP_185988.1 1136065 R 93062 CDS YP_185989.1 57651725 3237824 1137416..1138327 1 NC_002951.2 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 1138327 ctaB 3237824 ctaB Staphylococcus aureus subsp. aureus COL protoheme IX farnesyltransferase YP_185989.1 1137416 D 93062 CDS YP_185990.1 57651726 3237825 1138352..1138813 1 NC_002951.2 identified by similarity to EGAD:156110; match to protein family HMM PF04238; hypothetical protein 1138813 3237825 SACOL1126 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185990.1 1138352 D 93062 CDS YP_185991.1 57651727 3237309 1139025..1139228 1 NC_002951.2 hypothetical protein 1139228 3237309 SACOL1127 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185991.1 1139025 D 93062 CDS YP_185992.1 57651728 3237310 1139278..1140177 1 NC_002951.2 identified by similarity to OMNI:NT01BS1763; hypothetical protein 1140177 3237310 SACOL1128 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185992.1 1139278 D 93062 CDS YP_185993.1 57651729 3237311 1140193..1140627 1 NC_002951.2 identified by similarity to OMNI:NT01BS1766; match to protein family HMM PF07050; hypothetical protein 1140627 3237311 SACOL1129 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185993.1 1140193 D 93062 CDS YP_185994.1 57651730 3237312 complement(1140690..1141616) 1 NC_002951.2 identified by similarity to EGAD:9350; match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase 1141616 3237312 SACOL1130 Staphylococcus aureus subsp. aureus COL glycerophosphoryl diester phosphodiesterase YP_185994.1 1140690 R 93062 CDS YP_185995.1 57651731 3237313 1141855..1142109 1 NC_002951.2 identified by similarity to OMNI:EF2453; hypothetical protein 1142109 3237313 SACOL1131 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185995.1 1141855 D 93062 CDS YP_185996.1 57651732 3237314 complement(1142112..1142501) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH2594; hypothetical protein 1142501 3237314 SACOL1132 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185996.1 1142112 R 93062 CDS YP_185997.1 57651733 3237639 1142571..1143113 1 NC_002951.2 identified by similarity to EGAD:108192; match to protein family HMM PF03602; match to protein family HMM TIGR00095; hypothetical protein 1143113 3237639 SACOL1133 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185997.1 1142571 D 93062 CDS YP_185998.1 57651734 3237640 1143115..1143597 1 NC_002951.2 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1143597 coaD 3237640 coaD Staphylococcus aureus subsp. aureus COL phosphopantetheine adenylyltransferase YP_185998.1 1143115 D 93062 CDS YP_185999.1 57651735 3237641 complement(1143659..1144798) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH2588; match to protein family HMM PF05636; hypothetical protein 1144798 3237641 SACOL1135 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_185999.1 1143659 R 93062 CDS YP_186000.1 57651736 3237642 1144925..1145482 1 NC_002951.2 identified by similarity to GP:10175205; match to protein family HMM PF02620; hypothetical protein 1145482 3237642 SACOL1136 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186000.1 1144925 D 93062 CDS YP_186001.1 57651737 3237643 1145562..1145735 1 NC_002951.2 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1145735 rpmF 3237643 rpmF Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L32 YP_186001.1 1145562 D 93062 CDS YP_186002.1 57651738 3236095 complement(1145889..1147826) 1 NC_002951.2 identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF05031; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; LPXTG cell wall surface anchor protein 1147826 isdB 3236095 isdB Staphylococcus aureus subsp. aureus COL LPXTG cell wall surface anchor protein YP_186002.1 1145889 R 93062 CDS YP_186003.1 57651739 3236096 complement(1148029..1149081) 1 NC_002951.2 identified by match to protein family HMM PF00746; match to protein family HMM PF05031; match to protein family HMM TIGR01167; LPXTG cell wall surface anchor protein 1149081 isdA 3236096 isdA Staphylococcus aureus subsp. aureus COL LPXTG cell wall surface anchor protein YP_186003.1 1148029 R 93062 CDS YP_186004.1 57651740 3236097 1149290..1149973 1 NC_002951.2 identified by similarity to GP:10175922; match to protein family HMM PF05031; NPQTN cell wall surface anchor protein 1149973 isdC 3236097 isdC Staphylococcus aureus subsp. aureus COL NPQTN cell wall surface anchor protein YP_186004.1 1149290 D 93062 CDS YP_186005.1 57651741 3236098 1149973..1151049 1 NC_002951.2 hypothetical protein 1151049 isdD 3236098 isdD Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186005.1 1149973 D 93062 CDS YP_186006.1 57651742 3236099 1151046..1151924 1 NC_002951.2 identified by similarity to EGAD:16402; match to protein family HMM PF01497; iron compound ABC transporter iron compound-binding protein 1151924 3236099 SACOL1143 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter iron compound-binding protein YP_186006.1 1151046 D 93062 CDS YP_186007.1 57651743 3237660 1151937..1152902 1 NC_002951.2 identified by similarity to EGAD:7245; match to protein family HMM PF01032; iron compound ABC transporter permease 1152902 3237660 SACOL1144 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter permease YP_186007.1 1151937 D 93062 CDS YP_186008.1 57651744 3237661 1152964..1153698 1 NC_002951.2 identified by similarity to OMNI:NTL01BH3297; match to protein family HMM PF07170; sortase 1153698 srtB 3237661 srtB Staphylococcus aureus subsp. aureus COL sortase YP_186008.1 1152964 D 93062 CDS YP_186009.1 57651745 3237662 1153717..1154040 1 NC_002951.2 iron regulated; catalyzes the release of heme from hemoglobin allowing bacterial pathogens to use the host heme as an iron source; heme-degrading monooxygenase IsdG 1154040 3237662 SACOL1146 Staphylococcus aureus subsp. aureus COL heme-degrading monooxygenase IsdG YP_186009.1 1153717 D 93062 CDS YP_186010.1 57651746 3237663 1154424..1155164 1 NC_002951.2 identified by match to protein family HMM PF00588; RNA methyltransferase 1155164 3237663 SACOL1147 Staphylococcus aureus subsp. aureus COL RNA methyltransferase YP_186010.1 1154424 D 93062 CDS YP_186011.1 57651747 3237664 1155545..1156603 1 NC_002951.2 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1156603 pheS 3237664 pheS Staphylococcus aureus subsp. aureus COL phenylalanyl-tRNA synthetase subunit alpha YP_186011.1 1155545 D 93062 CDS YP_186012.1 57651748 3237665 1156603..1159005 1 NC_002951.2 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1159005 pheT 3237665 pheT Staphylococcus aureus subsp. aureus COL phenylalanyl-tRNA synthetase subunit beta YP_186012.1 1156603 D 93062 CDS YP_186013.1 57651749 3237649 complement(1159176..1160114) 1 NC_002951.2 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 1160114 rnhC 3237649 rnhC Staphylococcus aureus subsp. aureus COL ribonuclease HIII YP_186013.1 1159176 R 93062 CDS YP_186014.1 57651750 3237650 1160484..1160750 1 NC_002951.2 identified by similarity to EGAD:107725; match to protein family HMM PF05164; hypothetical protein 1160750 3237650 SACOL1151 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186014.1 1160484 D 93062 CDS YP_186015.1 57651751 3237651 1160751..1161272 1 NC_002951.2 identified by match to protein family HMM PF02674; hypothetical protein 1161272 3237651 SACOL1152 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186015.1 1160751 D 93062 CDS YP_186016.1 57651752 3237652 1161345..1163057 1 NC_002951.2 identified by match to protein family HMM PF02231; match to protein family HMM PF02811; hypothetical protein 1163057 3237652 SACOL1153 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186016.1 1161345 D 93062 CDS YP_186017.1 57651753 3237653 1163067..1165415 1 NC_002951.2 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange; recombination and DNA strand exchange inhibitor protein 1165415 3237653 SACOL1154 Staphylococcus aureus subsp. aureus COL recombination and DNA strand exchange inhibitor protein YP_186017.1 1163067 D 93062 CDS YP_186018.1 57651754 3237320 1165588..1165902 1 NC_002951.2 identified by similarity to SP:P14949; match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 1165902 trxA 3237320 trxA Staphylococcus aureus subsp. aureus COL thioredoxin YP_186018.1 1165588 D 93062 CDS YP_186019.1 57650255 3238637 complement(1165965..1166060) 1 NC_002951.2 hypothetical protein 1166060 3238637 SACOL1156 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186019.1 1165965 R 93062 CDS YP_186020.1 57650256 3238194 1166226..1168007 1 NC_002951.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1168007 uvrC 3238194 uvrC Staphylococcus aureus subsp. aureus COL excinuclease ABC subunit C YP_186020.1 1166226 D 93062 CDS YP_186021.1 57650257 3238335 1168331..1168945 1 NC_002951.2 identified by similarity to EGAD:20778; match to protein family HMM TIGR02046; succinate dehydrogenase, cytochrome b558 subunit 1168945 sdhC 3238335 sdhC Staphylococcus aureus subsp. aureus COL succinate dehydrogenase, cytochrome b558 subunit YP_186021.1 1168331 D 93062 CDS YP_186022.1 57650258 3238477 1168997..1170763 1 NC_002951.2 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 1170763 sdhA 3238477 sdhA Staphylococcus aureus subsp. aureus COL succinate dehydrogenase flavoprotein subunit YP_186022.1 1168997 D 93062 CDS YP_186023.1 57650259 3238001 1170763..1171578 1 NC_002951.2 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 1171578 sdhB 3238001 sdhB Staphylococcus aureus subsp. aureus COL succinate dehydrogenase iron-sulfur subunit YP_186023.1 1170763 D 93062 CDS YP_186024.1 57650260 3238222 1171814..1172614 1 NC_002951.2 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1172614 murI 3238222 murI Staphylococcus aureus subsp. aureus COL glutamate racemase YP_186024.1 1171814 D 93062 CDS YP_186025.1 57650261 3238373 1172626..1173213 1 NC_002951.2 hydrolyzes non-standard nucleotides such as xanthine and inosine; nucleoside-triphosphatase 1173213 3238373 SACOL1162 Staphylococcus aureus subsp. aureus COL nucleoside-triphosphatase YP_186025.1 1172626 D 93062 CDS YP_186026.1 57650262 3238469 1173206..1173709 1 NC_002951.2 identified by similarity to OMNI:NTL01BH3069; match to protein family HMM TIGR00040; hypothetical protein 1173709 3238469 SACOL1163 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186026.1 1173206 D 93062 CDS YP_186027.1 57650263 3238323 1174198..1174527 1 NC_002951.2 identified by similarity to EGAD:16905; fibrinogen binding-like protein 1174527 3238323 SACOL1164 Staphylococcus aureus subsp. aureus COL fibrinogen binding-like protein YP_186027.1 1174198 D 93062 CDS YP_186028.1 57650264 3238216 1174698..1174805 1 NC_002951.2 hypothetical protein 1174805 3238216 SACOL1165 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186028.1 1174698 D 93062 CDS YP_186029.1 57650265 3238392 complement(1174896..1175297) 1 NC_002951.2 FLIPr; secreted protein that blocks the formyl peptide receptor-like 1 (FPRL1) found in neutrophils, monocytes, B cells, and NK cells; inhibits the binding of chemoattractants (such as formylated peptides) to FPRL1, which initiates the phagocyte mobilization towards the infection site; formyl peptide receptor-like 1 inhibitory protein 1175297 3238392 SACOL1166 Staphylococcus aureus subsp. aureus COL formyl peptide receptor-like 1 inhibitory protein YP_186029.1 1174896 R 93062 CDS YP_186030.1 57650266 3238163 1175969..1176475 1 NC_002951.2 hypothetical protein 1176475 3238163 SACOL1167 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186030.1 1175969 D 93062 CDS YP_186031.1 57650267 3238454 1176734..1177231 1 NC_002951.2 identified by similarity to EGAD:16905; fibrinogen-binding protein 1177231 efb 3238454 efb Staphylococcus aureus subsp. aureus COL fibrinogen-binding protein YP_186031.1 1176734 D 93062 CDS YP_186032.1 57650268 3238697 1177385..1177735 1 NC_002951.2 fibrinogen-binding protein precursor-like protein 1177735 3238697 SACOL1169 Staphylococcus aureus subsp. aureus COL fibrinogen-binding protein precursor-like protein YP_186032.1 1177385 D 93062 CDS YP_186033.1 57650269 3238603 1178161..1178406 1 NC_002951.2 hypothetical protein 1178406 3238603 SACOL1170 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186033.1 1178161 D 93062 CDS YP_186034.1 57650270 3238139 complement(1178557..1178742) 1 NC_002951.2 hypothetical protein 1178742 3238139 SACOL1171 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186034.1 1178557 R 93062 CDS YP_186035.1 57650271 3238597 complement(1179364..1179597) 1 NC_002951.2 hypothetical protein 1179597 3238597 SACOL1172 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186035.1 1179364 R 93062 CDS YP_186036.1 57650272 3237999 complement(1180074..1181033) 1 NC_002951.2 identified by similarity to SP:P09616; match to protein family HMM PF01117; match to protein family HMM TIGR01002; alpha-hemolysin precursor 1181033 hlY 3237999 hlY Staphylococcus aureus subsp. aureus COL alpha-hemolysin precursor YP_186036.1 1180074 R 93062 CDS YP_186037.1 57650273 3238304 1181706..1181852 1 NC_002951.2 hypothetical protein 1181852 3238304 SACOL1174 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186037.1 1181706 D 93062 CDS YP_186038.1 57650274 3238126 1181836..1182033 1 NC_002951.2 hypothetical protein 1182033 3238126 SACOL1175 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186038.1 1181836 D 93062 CDS YP_186039.1 57650275 3238079 complement(1182065..1182313) 1 NC_002951.2 hypothetical protein 1182313 3238079 SACOL1176 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186039.1 1182065 R 93062 CDS YP_186040.1 57650276 3238517 1182290..1182421 1 NC_002951.2 hypothetical protein 1182421 3238517 SACOL1177 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186040.1 1182290 D 93062 CDS YP_186041.1 57650277 3238464 complement(1182590..1183306) 1 NC_002951.2 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 1183306 3238464 SACOL1178 Staphylococcus aureus subsp. aureus COL superantigen-like protein YP_186041.1 1182590 R 93062 CDS YP_186042.1 57650278 3238522 complement(1183414..1184139) 1 NC_002951.2 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 1184139 3238522 SACOL1179 Staphylococcus aureus subsp. aureus COL superantigen-like protein YP_186042.1 1183414 R 93062 CDS YP_186043.1 57650279 3238179 complement(1184234..1184959) 1 NC_002951.2 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 1184959 3238179 SACOL1180 Staphylococcus aureus subsp. aureus COL superantigen-like protein YP_186043.1 1184234 R 93062 CDS YP_186044.1 57650280 3238259 1185397..1186398 1 NC_002951.2 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 1186398 arcB1 3238259 arcB1 Staphylococcus aureus subsp. aureus COL ornithine carbamoyltransferase YP_186044.1 1185397 D 93062 CDS YP_186045.1 57650281 3238413 1186421..1187353 1 NC_002951.2 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 1187353 arcC1 3238413 arcC1 Staphylococcus aureus subsp. aureus COL carbamate kinase YP_186045.1 1186421 D 93062 CDS YP_186046.1 57650282 3238125 1187525..1189081 1 NC_002951.2 identified by match to protein family HMM PF03606; hypothetical protein 1189081 3238125 SACOL1183 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186046.1 1187525 D 93062 CDS YP_186047.1 57650283 3238559 complement(1189921..1190868) 1 NC_002951.2 exfoliative toxin 1190868 3238559 SACOL1184 Staphylococcus aureus subsp. aureus COL exfoliative toxin YP_186047.1 1189921 R 93062 CDS YP_186048.1 57650284 3238145 1191117..1191305 1 NC_002951.2 hypothetical protein 1191305 3238145 SACOL1185 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186048.1 1191117 D 93062 CDS YP_186049.1 57650285 3236432 1192217..1192351 1 NC_002951.2 identified by similarity to EGAD:9804; match to protein family HMM PF05480; anti protein (phenol soluble modulin) 1192351 3236432 SACOL1186 Staphylococcus aureus subsp. aureus COL anti protein (phenol soluble modulin) YP_186049.1 1192217 D 93062 CDS YP_186050.1 57650286 3236423 1192408..1192542 1 NC_002951.2 identified by similarity to EGAD:6344; match to protein family HMM PF05480; anti protein (phenol soluble modulin) 1192542 3236423 SACOL1187 Staphylococcus aureus subsp. aureus COL anti protein (phenol soluble modulin) YP_186050.1 1192408 D 93062 CDS YP_186051.1 57650287 3238615 1192666..1193361 1 NC_002951.2 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; match to protein family HMM TIGR02254; HAD superfamily hydrolase 1193361 3238615 SACOL1188 Staphylococcus aureus subsp. aureus COL HAD superfamily hydrolase YP_186051.1 1192666 D 93062 CDS YP_186052.1 57650288 3238607 complement(1193470..1193910) 1 NC_002951.2 identified by match to protein family HMM PF00583; hypothetical protein 1193910 3238607 SACOL1189 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186052.1 1193470 R 93062 CDS YP_186053.1 57650289 3236047 1194105..1195718 1 NC_002951.2 identified by similarity to EGAD:37696; hypothetical protein 1195718 3236047 SACOL1190 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186053.1 1194105 D 93062 CDS YP_186054.1 57650290 3238641 1195862..1196293 1 NC_002951.2 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 1196293 mraZ 3238641 mraZ Staphylococcus aureus subsp. aureus COL cell division protein MraZ YP_186054.1 1195862 D 93062 CDS YP_186055.1 57650291 3237962 1196309..1197244 1 NC_002951.2 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW 1197244 mraW 3237962 mraW Staphylococcus aureus subsp. aureus COL S-adenosyl-methyltransferase MraW YP_186055.1 1196309 D 93062 CDS YP_186056.1 57650292 3236134 1197273..1197659 1 NC_002951.2 identified by similarity to EGAD:21242; match to protein family HMM TIGR02209; cell division protein 1197659 3236134 SACOL1193 Staphylococcus aureus subsp. aureus COL cell division protein YP_186056.1 1197273 D 93062 CDS YP_186057.1 57650293 3236102 1197640..1199874 1 NC_002951.2 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF03793; penicillin-binding protein 1 1199874 pbp1 3236102 pbp1 Staphylococcus aureus subsp. aureus COL penicillin-binding protein 1 YP_186057.1 1197640 D 93062 CDS YP_186058.1 57650294 3236112 1200166..1201131 1 NC_002951.2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1201131 mraY 3236112 mraY Staphylococcus aureus subsp. aureus COL phospho-N-acetylmuramoyl-pentapeptide- transferase YP_186058.1 1200166 D 93062 CDS YP_186059.1 57650295 3238515 1201133..1202482 1 NC_002951.2 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 1202482 murD 3238515 murD Staphylococcus aureus subsp. aureus COL UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_186059.1 1201133 D 93062 CDS YP_186060.1 57650296 3238331 1202498..1203817 1 NC_002951.2 identified by similarity to EGAD:18732; match to protein family HMM PF03799; cell division protein 1203817 divIB 3238331 divIB Staphylococcus aureus subsp. aureus COL cell division protein YP_186060.1 1202498 D 93062 CDS YP_186061.1 57651755 3237321 1203923..1205335 1 NC_002951.2 identified by similarity to EGAD:18700; match to protein family HMM PF02491; match to protein family HMM TIGR01174; cell division protein FtsA 1205335 ftsA 3237321 ftsA Staphylococcus aureus subsp. aureus COL cell division protein FtsA YP_186061.1 1203923 D 93062 CDS YP_186062.1 57651756 3237322 1205368..1206540 1 NC_002951.2 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1206540 ftsZ 3237322 ftsZ Staphylococcus aureus subsp. aureus COL cell division protein FtsZ YP_186062.1 1205368 D 93062 CDS YP_186063.1 57651757 3237323 1206800..1207591 1 NC_002951.2 identified by similarity to EGAD:108215; match to protein family HMM PF02578; match to protein family HMM TIGR00726; hypothetical protein 1207591 3237323 SACOL1200 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186063.1 1206800 D 93062 CDS YP_186064.1 57651758 3237324 1207609..1208283 1 NC_002951.2 identified by similarity to EGAD:108216; match to protein family HMM PF01168; match to protein family HMM TIGR00044; hypothetical protein 1208283 3237324 SACOL1201 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186064.1 1207609 D 93062 CDS YP_186065.1 57651759 3237863 1208280..1208843 1 NC_002951.2 identified by match to protein family HMM PF04472; hypothetical protein 1208843 ylmF 3237863 ylmF Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186065.1 1208280 D 93062 CDS YP_186066.1 57651760 3237864 1208855..1209145 1 NC_002951.2 identified by match to protein family HMM PF02325; hypothetical protein 1209145 ylmG 3237864 ylmG Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186066.1 1208855 D 93062 CDS YP_186067.1 57651761 3237865 1209255..1210034 1 NC_002951.2 identified by similarity to GP:4009474; match to protein family HMM PF01479; YlmH protein 1210034 ylmH 3237865 ylmH Staphylococcus aureus subsp. aureus COL YlmH protein YP_186067.1 1209255 D 93062 CDS YP_186068.1 57651762 3237866 1210058..1210675 1 NC_002951.2 identified by match to protein family HMM PF05103; hypothetical protein 1210675 3237866 SACOL1205 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186068.1 1210058 D 93062 CDS YP_186069.1 57651763 3237867 1210896..1213649 1 NC_002951.2 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1213649 ileS 3237867 ileS Staphylococcus aureus subsp. aureus COL isoleucyl-tRNA synthetase YP_186069.1 1210896 D 93062 CDS YP_186070.1 57651764 3237154 1213939..1214736 1 NC_002951.2 identified by match to protein family HMM PF00903; glyoxalase 1214736 3237154 SACOL1207 Staphylococcus aureus subsp. aureus COL glyoxalase YP_186070.1 1213939 D 93062 CDS YP_186071.1 57651765 3237155 1215560..1216051 1 NC_002951.2 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1216051 lspA 3237155 lspA Staphylococcus aureus subsp. aureus COL lipoprotein signal peptidase YP_186071.1 1215560 D 93062 CDS YP_186072.1 57651766 3237156 1216051..1216968 1 NC_002951.2 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase D 1216968 3237156 SACOL1209 Staphylococcus aureus subsp. aureus COL ribosomal large subunit pseudouridine synthase D YP_186072.1 1216051 D 93062 CDS YP_186073.1 57651767 3237157 1217368..1217895 1 NC_002951.2 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase 1217895 pyrR 3237157 pyrR Staphylococcus aureus subsp. aureus COL bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase YP_186073.1 1217368 D 93062 CDS YP_186074.1 57651768 3237158 1218113..1219420 1 NC_002951.2 identified by similarity to EGAD:20988; match to protein family HMM PF00860; match to protein family HMM TIGR00801; uracil permease 1219420 uraA 3237158 uraA Staphylococcus aureus subsp. aureus COL uracil permease YP_186074.1 1218113 D 93062 CDS YP_186075.1 57651769 3237655 1219448..1220329 1 NC_002951.2 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 1220329 pyrB 3237655 pyrB Staphylococcus aureus subsp. aureus COL aspartate carbamoyltransferase catalytic subunit YP_186075.1 1219448 D 93062 CDS YP_186076.1 57651770 3237656 1220347..1221621 1 NC_002951.2 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1221621 pyrC 3237656 pyrC Staphylococcus aureus subsp. aureus COL dihydroorotase YP_186076.1 1220347 D 93062 CDS YP_186077.1 57651771 3237657 1221623..1222723 1 NC_002951.2 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1222723 carA 3237657 carA Staphylococcus aureus subsp. aureus COL carbamoyl phosphate synthase small subunit YP_186077.1 1221623 D 93062 CDS YP_186078.1 57651772 3237658 1222716..1225889 1 NC_002951.2 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1225889 carB 3237658 carB Staphylococcus aureus subsp. aureus COL carbamoyl phosphate synthase large subunit YP_186078.1 1222716 D 93062 CDS YP_186079.1 57651773 3237659 1225999..1226691 1 NC_002951.2 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1226691 pyrF 3237659 pyrF Staphylococcus aureus subsp. aureus COL orotidine 5'-phosphate decarboxylase YP_186079.1 1225999 D 93062 CDS YP_186080.1 57651774 3236135 1226691..1227302 1 NC_002951.2 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1227302 pyrE 3236135 pyrE Staphylococcus aureus subsp. aureus COL orotate phosphoribosyltransferase YP_186080.1 1226691 D 93062 CDS YP_186081.1 57651775 3236136 1227332..1227544 1 NC_002951.2 identified by similarity to GB:AAO04479.1; hypothetical protein 1227544 3236136 SACOL1218 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186081.1 1227332 D 93062 CDS YP_186082.1 57651776 3236137 1227981..1228382 1 NC_002951.2 identified by similarity to OMNI:NTL03PA01359; hypothetical protein 1228382 3236137 SACOL1219 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186082.1 1227981 D 93062 CDS YP_186083.1 57651777 3236138 complement(1228645..1230342) 1 NC_002951.2 identified by match to protein family HMM PF05670; match to protein family HMM PF05833; fibronectin/fibrinogen binding-like protein 1230342 3236138 SACOL1220 Staphylococcus aureus subsp. aureus COL fibronectin/fibrinogen binding-like protein YP_186083.1 1228645 R 93062 CDS YP_186084.1 57651778 3236139 1230617..1231240 1 NC_002951.2 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1231240 gmk 3236139 gmk Staphylococcus aureus subsp. aureus COL guanylate kinase YP_186084.1 1230617 D 93062 CDS YP_186085.1 57651779 3236140 1231240..1231458 1 NC_002951.2 Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 1231458 rpoZ 3236140 rpoZ Staphylococcus aureus subsp. aureus COL DNA-directed RNA polymerase subunit omega YP_186085.1 1231240 D 93062 CDS YP_186086.1 57651780 3237848 1231668..1232873 1 NC_002951.2 identified by similarity to SP:P24285; match to protein family HMM PF02441; match to protein family HMM PF04127; match to protein family HMM TIGR00521; phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase 1232873 coaBC 3237848 coaBC Staphylococcus aureus subsp. aureus COL phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase YP_186086.1 1231668 D 93062 CDS YP_186087.1 57651781 3237849 1232873..1235281 1 NC_002951.2 identified by similarity to EGAD:98914; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851; match to protein family HMM TIGR00595; primosomal protein N` 1235281 priA 3237849 priA Staphylococcus aureus subsp. aureus COL primosomal protein N` YP_186087.1 1232873 D 93062 CDS YP_186088.1 57651782 3237850 1235787..1236740 1 NC_002951.2 hypothetical protein 1236740 3237850 SACOL1225 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186088.1 1235787 D 93062 CDS YP_186089.1 57651783 3237851 complement(1236903..1237181) 1 NC_002951.2 identified by similarity to EGAD:47675; match to protein family HMM PF05154; hypothetical protein 1237181 3237851 SACOL1226 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186089.1 1236903 R 93062 CDS YP_186090.1 57651784 3237852 1237405..1237893 1 NC_002951.2 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1237893 def2 3237852 def2 Staphylococcus aureus subsp. aureus COL peptide deformylase YP_186090.1 1237405 D 93062 CDS YP_186091.1 57651785 3237966 1237886..1238821 1 NC_002951.2 identified by match to protein family HMM PF00551; match to protein family HMM PF02911; match to protein family HMM TIGR00460; methionyl-tRNA formyltransferase 1238821 fmt 3237966 fmt Staphylococcus aureus subsp. aureus COL methionyl-tRNA formyltransferase YP_186091.1 1237886 D 93062 CDS YP_186092.1 57651786 3237967 1238818..1240125 1 NC_002951.2 identified by match to protein family HMM PF01029; match to protein family HMM PF01189; match to protein family HMM TIGR00563; sun protein 1240125 sun 3237967 sun Staphylococcus aureus subsp. aureus COL sun protein YP_186092.1 1238818 D 93062 CDS YP_186093.1 57651787 3237968 1240128..1241222 1 NC_002951.2 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1241222 3237968 SACOL1230 Staphylococcus aureus subsp. aureus COL ribosomal RNA large subunit methyltransferase N YP_186093.1 1240128 D 93062 CDS YP_186094.1 57651788 3237969 1241229..1241972 1 NC_002951.2 identified by match to protein family HMM PF00481; protein phosphatase 2C domain-containing protein 1241972 3237969 SACOL1231 Staphylococcus aureus subsp. aureus COL protein phosphatase 2C domain-containing protein YP_186094.1 1241229 D 93062 CDS YP_186095.1 57651789 3237951 1244191..1245066 1 NC_002951.2 identified by similarity to EGAD:108267; match to protein family HMM PF03193; match to protein family HMM TIGR00157; hypothetical protein 1245066 3237951 SACOL1234 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186095.1 1244191 D 93062 CDS YP_186096.1 57651790 3237952 1245067..1245711 1 NC_002951.2 identified by match to protein family HMM PF00834; match to protein family HMM TIGR01163; ribulose-phosphate 3-epimerase 1245711 rpe 3237952 rpe Staphylococcus aureus subsp. aureus COL ribulose-phosphate 3-epimerase YP_186096.1 1245067 D 93062 CDS YP_186097.1 57651791 3237953 1245718..1246359 1 NC_002951.2 identified by similarity to EGAD:108271; match to protein family HMM PF04263; match to protein family HMM PF04265; match to protein family HMM TIGR01378; hypothetical protein 1246359 3237953 SACOL1236 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186097.1 1245718 D 93062 CDS YP_186098.1 57651792 3237954 complement(1246740..1246928) 1 NC_002951.2 required for 70S ribosome assembly; 50S ribosomal protein L28 1246928 rpmB 3237954 rpmB Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L28 YP_186098.1 1246740 R 93062 CDS YP_186099.1 57651793 3237955 1247371..1247745 1 NC_002951.2 identified by similarity to EGAD:108275; match to protein family HMM PF03780; hypothetical protein 1247745 3237955 SACOL1239 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186099.1 1247371 D 93062 CDS YP_186100.1 57651794 3238621 1247760..1249406 1 NC_002951.2 identified by match to protein family HMM PF02734; DAK2 domain-containing protein 1249406 3238621 SACOL1240 Staphylococcus aureus subsp. aureus COL DAK2 domain-containing protein YP_186100.1 1247760 D 93062 CDS YP_186101.1 57651795 3238622 1249596..1251656 1 NC_002951.2 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1251656 recG 3238622 recG Staphylococcus aureus subsp. aureus COL ATP-dependent DNA helicase RecG YP_186101.1 1249596 D 93062 CDS YP_186102.1 57651796 3238623 1251859..1252431 1 NC_002951.2 negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria; fatty acid biosynthesis transcriptional regulator 1252431 3238623 SACOL1242 Staphylococcus aureus subsp. aureus COL fatty acid biosynthesis transcriptional regulator YP_186102.1 1251859 D 93062 CDS YP_186103.1 57651797 3238624 1252436..1253422 1 NC_002951.2 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1253422 plsX 3238624 plsX Staphylococcus aureus subsp. aureus COL glycerol-3-phosphate acyltransferase PlsX YP_186103.1 1252436 D 93062 CDS YP_186104.1 57651798 3238625 1253415..1254341 1 NC_002951.2 identified by similarity to EGAD:97846; match to protein family HMM PF00698; match to protein family HMM TIGR00128; malonyl CoA-ACP transacylase 1254341 fabD 3238625 fabD Staphylococcus aureus subsp. aureus COL malonyl CoA-ACP transacylase YP_186104.1 1253415 D 93062 CDS YP_186105.1 57651799 3238574 1254334..1255068 1 NC_002951.2 identified by similarity to EGAD:108288; match to protein family HMM PF00106; match to protein family HMM TIGR01830; 3-oxoacyl-ACP reductase 1255068 fabG1 3238574 fabG1 Staphylococcus aureus subsp. aureus COL 3-oxoacyl-ACP reductase YP_186105.1 1254334 D 93062 CDS YP_186106.1 57651800 3238575 complement(1255191..1255289) 1 NC_002951.2 hypothetical protein 1255289 3238575 SACOL1246 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186106.1 1255191 R 93062 CDS YP_186107.1 57651801 3238576 1255311..1255544 1 NC_002951.2 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1255544 acpP 3238576 acpP Staphylococcus aureus subsp. aureus COL acyl carrier protein YP_186107.1 1255311 D 93062 CDS YP_186108.1 57651802 3238577 1255660..1256391 1 NC_002951.2 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1256391 rnc 3238577 rnc Staphylococcus aureus subsp. aureus COL ribonuclease III YP_186108.1 1255660 D 93062 CDS YP_186109.1 57651803 3238578 1256538..1260104 1 NC_002951.2 identified by similarity to EGAD:37839; match to protein family HMM PF02463; match to protein family HMM PF02483; match to protein family HMM PF06470; match to protein family HMM TIGR00650; match to protein family HMM TIGR02168; chromosome segregation protein SMC 1260104 3238578 SACOL1250 Staphylococcus aureus subsp. aureus COL chromosome segregation protein SMC YP_186109.1 1256538 D 93062 CDS YP_186110.1 57651804 3238080 1260104..1261354 1 NC_002951.2 identified by match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064; cell division protein FtsY 1261354 3238080 SACOL1251 Staphylococcus aureus subsp. aureus COL cell division protein FtsY YP_186110.1 1260104 D 93062 CDS YP_186111.1 57651805 3238081 1261341..1261673 1 NC_002951.2 identified by similarity to OMNI:NTL01BH2488; match to protein family HMM PF04297; DNA-binding protein 1261673 3238081 SACOL1252 Staphylococcus aureus subsp. aureus COL DNA-binding protein YP_186111.1 1261341 D 93062 CDS YP_186112.1 57651806 3238082 1261699..1263066 1 NC_002951.2 identified by similarity to EGAD:5600; match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959; signal recognition particle protein 1263066 ffh 3238082 ffh Staphylococcus aureus subsp. aureus COL signal recognition particle protein YP_186112.1 1261699 D 93062 CDS YP_186113.1 57651807 3238083 1263501..1263776 1 NC_002951.2 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1263776 rpsP 3238083 rpsP Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S16 YP_186113.1 1263501 D 93062 CDS YP_186114.1 57651808 3238084 1263964..1264467 1 NC_002951.2 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1264467 rimM 3238084 rimM Staphylococcus aureus subsp. aureus COL 16S rRNA-processing protein RimM YP_186114.1 1263964 D 93062 CDS YP_186115.1 57651809 3238165 1264467..1265204 1 NC_002951.2 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1265204 trmD 3238165 trmD Staphylococcus aureus subsp. aureus COL tRNA (guanine-N(1)-)-methyltransferase YP_186115.1 1264467 D 93062 CDS YP_186116.1 57651810 3238166 1265307..1265657 1 NC_002951.2 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1265657 rplS 3238166 rplS Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L19 YP_186116.1 1265307 D 93062 CDS YP_186117.1 57651811 3238167 complement(1265901..1268507) 1 NC_002951.2 identified by similarity to EGAD:108285; hypothetical protein 1268507 3238167 SACOL1259 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186117.1 1265901 R 93062 CDS YP_186118.1 57651812 3238168 1268908..1269792 1 NC_002951.2 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 1269792 rbgA 3238168 rbgA Staphylococcus aureus subsp. aureus COL ribosomal biogenesis GTPase YP_186118.1 1268908 D 93062 CDS YP_186119.1 57651813 3238169 1269776..1270543 1 NC_002951.2 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1270543 rnhB 3238169 rnhB Staphylococcus aureus subsp. aureus COL ribonuclease HII YP_186119.1 1269776 D 93062 CDS YP_186120.1 57651814 3238170 1270652..1271818 1 NC_002951.2 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1271818 sucC 3238170 sucC Staphylococcus aureus subsp. aureus COL succinyl-CoA synthetase subunit beta YP_186120.1 1270652 D 93062 CDS YP_186121.1 57651815 3238355 1271840..1272748 1 NC_002951.2 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 1272748 sucD 3238355 sucD Staphylococcus aureus subsp. aureus COL succinyl-CoA synthetase subunit alpha YP_186121.1 1271840 D 93062 CDS YP_186122.1 57651816 3238356 1272942..1274093 1 NC_002951.2 identified by similarity to GP:3767593; match to protein family HMM PF01476; match to protein family HMM PF04650; match to protein family HMM PF05257; match to protein family HMM TIGR01168; cell wall hydrolase 1274093 lytN 3238356 lytN Staphylococcus aureus subsp. aureus COL cell wall hydrolase YP_186122.1 1272942 D 93062 CDS YP_186123.1 57651817 3238357 1274121..1275365 1 NC_002951.2 identified by match to protein family HMM PF02388; endopeptidase resistance gene 1275365 eprH 3238357 eprH Staphylococcus aureus subsp. aureus COL endopeptidase resistance gene YP_186123.1 1274121 D 93062 CDS YP_186124.1 57651818 3238358 1275538..1276410 1 NC_002951.2 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732; DNA processing protein DprA 1276410 3238358 SACOL1266 Staphylococcus aureus subsp. aureus COL DNA processing protein DprA YP_186124.1 1275538 D 93062 CDS YP_186125.1 57651819 3238359 1276590..1278659 1 NC_002951.2 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1278659 topA 3238359 topA Staphylococcus aureus subsp. aureus COL DNA topoisomerase I YP_186125.1 1276590 D 93062 CDS YP_186126.1 57651820 3238029 1278815..1280122 1 NC_002951.2 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 1280122 gid 3238029 gid Staphylococcus aureus subsp. aureus COL tRNA (uracil-5-)-methyltransferase Gid YP_186126.1 1278815 D 93062 CDS YP_186127.1 57651821 3238030 1280539..1281435 1 NC_002951.2 identified by similarity to EGAD:14579; similarity to GP:9622622; match to protein family HMM PF00589; match to protein family HMM PF02899; match to protein family HMM TIGR02224; tyrosine recombinase XerC 1281435 xerC 3238030 xerC Staphylococcus aureus subsp. aureus COL tyrosine recombinase XerC YP_186127.1 1280539 D 93062 CDS YP_186128.1 57651822 3238031 1281432..1281977 1 NC_002951.2 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 1281977 hslV 3238031 hslV Staphylococcus aureus subsp. aureus COL ATP-dependent protease peptidase subunit YP_186128.1 1281432 D 93062 CDS YP_186129.1 57651823 3238032 1282043..1283446 1 NC_002951.2 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 1283446 hslU 3238032 hslU Staphylococcus aureus subsp. aureus COL ATP-dependent protease ATP-binding subunit HslU YP_186129.1 1282043 D 93062 CDS YP_186130.1 57651824 3238033 1283471..1284244 1 NC_002951.2 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 1284244 codY 3238033 codY Staphylococcus aureus subsp. aureus COL transcriptional repressor CodY YP_186130.1 1283471 D 93062 CDS YP_186131.2 408843730 3238505 1284586..>1285350 1 NC_002951.2 truncated; one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 >1285350 rpsB 3238505 rpsB Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S2 YP_186131.2 1284586 D 93062 CDS YP_186132.1 57651826 3238506 1285396..1285509 1 NC_002951.2 hypothetical protein 1285509 3238506 SACOL1275 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186132.1 1285396 D 93062 CDS YP_186133.1 57651827 3238507 1285544..1286425 1 NC_002951.2 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1286425 tsf 3238507 tsf Staphylococcus aureus subsp. aureus COL elongation factor Ts YP_186133.1 1285544 D 93062 CDS YP_186134.1 57651828 3238508 1286562..1287284 1 NC_002951.2 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1287284 pyrH 3238508 pyrH Staphylococcus aureus subsp. aureus COL uridylate kinase YP_186134.1 1286562 D 93062 CDS YP_186135.1 57651829 3238509 1287303..1287857 1 NC_002951.2 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1287857 frr 3238509 frr Staphylococcus aureus subsp. aureus COL ribosome recycling factor YP_186135.1 1287303 D 93062 CDS YP_186136.1 57651830 3238385 1288230..1289000 1 NC_002951.2 catalyzes the formation of UDP pyrophosphate from isopentenyl pyrophosphate; UDP pyrophosphate synthase 1289000 uppS 3238385 uppS Staphylococcus aureus subsp. aureus COL UDP pyrophosphate synthase YP_186136.1 1288230 D 93062 CDS YP_186137.1 57651831 3238386 1289007..1289789 1 NC_002951.2 identified by similarity to EGAD:108469; match to protein family HMM PF01148; phosphatidate cytidylyltransferase 1289789 cdsA 3238386 cdsA Staphylococcus aureus subsp. aureus COL phosphatidate cytidylyltransferase YP_186137.1 1289007 D 93062 CDS YP_186138.1 57651832 3238387 1290026..1291312 1 NC_002951.2 identified by match to protein family HMM PF02163; match to protein family HMM TIGR00054; membrane-associated zinc metalloprotease 1291312 3238387 SACOL1281 Staphylococcus aureus subsp. aureus COL membrane-associated zinc metalloprotease YP_186138.1 1290026 D 93062 CDS YP_186139.1 57651833 3238388 1291332..1293035 1 NC_002951.2 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 1293035 proS 3238388 proS Staphylococcus aureus subsp. aureus COL prolyl-tRNA synthetase YP_186139.1 1291332 D 93062 CDS YP_186140.1 57651834 3238389 1293299..1297609 1 NC_002951.2 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 1297609 polC 3238389 polC Staphylococcus aureus subsp. aureus COL DNA polymerase III PolC YP_186140.1 1293299 D 93062 CDS YP_186141.1 57651835 3238341 1297899..1298366 1 NC_002951.2 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1298366 3238341 SACOL1284 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186141.1 1297899 D 93062 CDS YP_186142.1 57651836 3238342 1298387..1299562 1 NC_002951.2 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1299562 nusA 3238342 nusA Staphylococcus aureus subsp. aureus COL transcription elongation factor NusA YP_186142.1 1298387 D 93062 CDS YP_186143.1 57651837 3238343 1299583..1299867 1 NC_002951.2 identified by similarity to OMNI:NTL01BH2418; match to protein family HMM PF04296; hypothetical protein 1299867 3238343 SACOL1286 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186143.1 1299583 D 93062 CDS YP_186144.1 57651838 3238344 1299864..1300181 1 NC_002951.2 identified by similarity to EGAD:9717; match to protein family HMM PF01248; 50S ribosomal protein L7 1300181 3238344 SACOL1287 Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L7 YP_186144.1 1299864 D 93062 CDS YP_186145.1 57651839 3238345 1300186..1302303 1 NC_002951.2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1302303 infB 3238345 infB Staphylococcus aureus subsp. aureus COL translation initiation factor IF-2 YP_186145.1 1300186 D 93062 CDS YP_186146.1 57651840 3238346 1302689..1303039 1 NC_002951.2 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1303039 rbfA 3238346 rbfA Staphylococcus aureus subsp. aureus COL ribosome-binding factor A YP_186146.1 1302689 D 93062 CDS YP_186147.1 57651841 3236225 1303208..1304125 1 NC_002951.2 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1304125 truB 3236225 truB Staphylococcus aureus subsp. aureus COL tRNA pseudouridine synthase B YP_186147.1 1303208 D 93062 CDS YP_186148.1 57651842 3236226 1304140..1305111 1 NC_002951.2 identified by similarity to SP:P54575; match to protein family HMM PF01687; match to protein family HMM PF06574; match to protein family HMM TIGR00083; riboflavin biosynthesis protein RibF 1305111 ribF 3236226 ribF Staphylococcus aureus subsp. aureus COL riboflavin biosynthesis protein RibF YP_186148.1 1304140 D 93062 CDS YP_186149.1 57651843 3236227 1305226..1305495 1 NC_002951.2 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1305495 rpsO 3236227 rpsO Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S15 YP_186149.1 1305226 D 93062 CDS YP_186150.1 57651844 3236228 1305865..1307961 1 NC_002951.2 identified by similarity to SP:P50849; match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; polynucleotide phosphorylase/polyadenylase 1307961 pnp 3236228 pnp Staphylococcus aureus subsp. aureus COL polynucleotide phosphorylase/polyadenylase YP_186150.1 1305865 D 93062 CDS YP_186151.1 57651845 3236229 1308299..1309870 1 NC_002951.2 identified by match to protein family HMM PF00753; match to protein family HMM PF07521; metallo-beta-lactamase 1309870 3236229 SACOL1294 Staphylococcus aureus subsp. aureus COL metallo-beta-lactamase YP_186151.1 1308299 D 93062 CDS YP_186152.1 57651846 3236219 1310117..1312495 1 NC_002951.2 identified by similarity to EGAD:23720; match to protein family HMM PF01580; FtsK/SpoIIIE family protein 1312495 3236219 SACOL1295 Staphylococcus aureus subsp. aureus COL FtsK/SpoIIIE family protein YP_186152.1 1310117 D 93062 CDS YP_186153.1 57651847 3236220 1312500..1313213 1 NC_002951.2 identified by match to protein family HMM PF07702; GntR family transcriptional regulator 1313213 3236220 SACOL1296 Staphylococcus aureus subsp. aureus COL GntR family transcriptional regulator YP_186153.1 1312500 D 93062 CDS YP_186154.1 57651848 3236221 1313244..1314509 1 NC_002951.2 identified by similarity to OMNI:NTL01BH2396; match to protein family HMM PF05193; hypothetical protein 1314509 3236221 SACOL1297 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186154.1 1313244 D 93062 CDS YP_186155.1 57651849 3236222 1314509..1315795 1 NC_002951.2 identified by match to protein family HMM PF00675; match to protein family HMM PF05193; M16 family peptidase 1315795 3236222 SACOL1298 Staphylococcus aureus subsp. aureus COL M16 family peptidase YP_186155.1 1314509 D 93062 CDS YP_186156.1 57651850 3236223 1315795..1316499 1 NC_002951.2 identified by similarity to GP:10175011; match to protein family HMM PF00106; acetoacetyl-CoA reductase 1316499 3236223 SACOL1299 Staphylococcus aureus subsp. aureus COL acetoacetyl-CoA reductase YP_186156.1 1315795 D 93062 CDS YP_186157.1 57651851 3236224 1316604..1317431 1 NC_002951.2 identified by similarity to GP:10175009; ACT domain-containing protein 1317431 3236224 SACOL1300 Staphylococcus aureus subsp. aureus COL ACT domain-containing protein YP_186157.1 1316604 D 93062 CDS YP_186158.1 57651852 3236360 1317450..1317842 1 NC_002951.2 transcriptional regulator 1317842 3236360 SACOL1301 Staphylococcus aureus subsp. aureus COL transcriptional regulator YP_186158.1 1317450 D 93062 CDS YP_186159.1 57651853 3236361 1317876..1318454 1 NC_002951.2 identified by similarity to EGAD:30182; match to protein family HMM PF01066; match to protein family HMM TIGR00560; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1318454 pgsA 3236361 pgsA Staphylococcus aureus subsp. aureus COL CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_186159.1 1317876 D 93062 CDS YP_186160.1 57651854 3236362 1318681..1319832 1 NC_002951.2 identified by similarity to EGAD:108567; match to protein family HMM PF00994; match to protein family HMM TIGR00200; competence/damage-inducible protein CinA 1319832 3236362 SACOL1303 Staphylococcus aureus subsp. aureus COL competence/damage-inducible protein CinA YP_186160.1 1318681 D 93062 CDS YP_186161.1 57651855 3236363 1319997..1321040 1 NC_002951.2 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1321040 recA 3236363 recA Staphylococcus aureus subsp. aureus COL recombinase A YP_186161.1 1319997 D 93062 CDS YP_186162.1 57651856 3236364 1321394..1322953 1 NC_002951.2 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 1322953 3236364 SACOL1305 Staphylococcus aureus subsp. aureus COL phosphodiesterase YP_186162.1 1321394 D 93062 CDS YP_186163.1 57651857 3236365 complement(1323250..1323465) 1 NC_002951.2 identified by similarity to GB:AAO04562.1; hypothetical protein 1323465 3236365 SACOL1306 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186163.1 1323250 R 93062 CDS YP_186164.1 57651858 3236354 1323639..1324436 1 NC_002951.2 identified by similarity to EGAD:108574; match to protein family HMM PF00149; match to protein family HMM TIGR00282; hypothetical protein 1324436 3236354 SACOL1307 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186164.1 1323639 D 93062 CDS YP_186165.1 57651859 3236355 1324576..1326336 1 NC_002951.2 identified by match to protein family HMM PF01558; match to protein family HMM PF01855; pyruvate ferredoxin oxidoreductase subunit alpha 1326336 3236355 SACOL1308 Staphylococcus aureus subsp. aureus COL pyruvate ferredoxin oxidoreductase subunit alpha YP_186165.1 1324576 D 93062 CDS YP_186166.1 57651860 3236356 1326337..1327203 1 NC_002951.2 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; 2-oxoglutarate ferredoxin oxidoreductase subunit beta 1327203 3236356 SACOL1309 Staphylococcus aureus subsp. aureus COL 2-oxoglutarate ferredoxin oxidoreductase subunit beta YP_186166.1 1326337 D 93062 CDS YP_186167.1 57651861 3236357 1327297..1327590 1 NC_002951.2 hypothetical protein 1327590 3236357 SACOL1310 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186167.1 1327297 D 93062 CDS YP_186168.1 57651862 3236358 1327724..1329268 1 NC_002951.2 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1329268 miaB 3236358 miaB Staphylococcus aureus subsp. aureus COL (dimethylallyl)adenosine tRNA methylthiotransferase YP_186168.1 1327724 D 93062 CDS YP_186169.1 57651863 3236359 1329269..1329634 1 NC_002951.2 identified by similarity to EGAD:108740; hypothetical protein 1329634 3236359 SACOL1313 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186169.1 1329269 D 93062 CDS YP_186170.1 57651864 3236061 1329661..1330152 1 NC_002951.2 identified by similarity to OMNI:EF2778; match to protein family HMM TIGR02359; hypothetical protein 1330152 3236061 SACOL1314 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186170.1 1329661 D 93062 CDS YP_186171.1 57651865 3236062 1330455..1333073 1 NC_002951.2 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1333073 hexA 3236062 hexA Staphylococcus aureus subsp. aureus COL DNA mismatch repair protein MutS YP_186171.1 1330455 D 93062 CDS YP_186172.1 57651866 3236063 1333086..1335095 1 NC_002951.2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 1335095 mutL 3236063 mutL Staphylococcus aureus subsp. aureus COL DNA mismatch repair protein YP_186172.1 1333086 D 93062 CDS YP_186173.1 57651867 3236064 1335101..1335643 1 NC_002951.2 identified by similarity to EGAD:18158; match to protein family HMM PF04309; glycerol uptake operon antiterminator regulatory protein 1335643 glpP 3236064 glpP Staphylococcus aureus subsp. aureus COL glycerol uptake operon antiterminator regulatory protein YP_186173.1 1335101 D 93062 CDS YP_186174.1 57651868 3236065 1336108..1336926 1 NC_002951.2 identified by similarity to EGAD:21817; match to protein family HMM PF00230; match to protein family HMM TIGR00861; glycerol uptake facilitator protein 1336926 glpF 3236065 glpF Staphylococcus aureus subsp. aureus COL glycerol uptake facilitator protein YP_186174.1 1336108 D 93062 CDS YP_186175.1 57651869 3236394 1337055..1338551 1 NC_002951.2 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 1338551 glpK 3236394 glpK Staphylococcus aureus subsp. aureus COL glycerol kinase YP_186175.1 1337055 D 93062 CDS YP_186176.1 57651870 3236395 1338709..1340382 1 NC_002951.2 identified by similarity to EGAD:18115; match to protein family HMM PF01266; aerobic glycerol-3-phosphate dehydrogenase 1340382 glpD 3236395 glpD Staphylococcus aureus subsp. aureus COL aerobic glycerol-3-phosphate dehydrogenase YP_186176.1 1338709 D 93062 CDS YP_186177.1 57651871 3236396 1340532..1341446 1 NC_002951.2 identified by match to protein family HMM PF00561; alpha/beta fold family hydrolase 1341446 3236396 SACOL1322 Staphylococcus aureus subsp. aureus COL alpha/beta fold family hydrolase YP_186177.1 1340532 D 93062 CDS YP_186178.1 57651872 3236397 1341464..1342399 1 NC_002951.2 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1342399 miaA 3236397 miaA Staphylococcus aureus subsp. aureus COL tRNA delta(2)-isopentenylpyrophosphate transferase YP_186178.1 1341464 D 93062 CDS YP_186179.1 57651873 3236398 1342414..1342647 1 NC_002951.2 identified by similarity to EGAD:12661; match to protein family HMM PF01423; hfq protein 1342647 3236398 SACOL1324 Staphylococcus aureus subsp. aureus COL hfq protein YP_186179.1 1342414 D 93062 CDS YP_186180.1 57651874 3236399 complement(1342869..1343345) 1 NC_002951.2 identified by similarity to EGAD:45646; match to protein family HMM PF00255; glutathione peroxidase 1343345 gpxA1 3236399 gpxA1 Staphylococcus aureus subsp. aureus COL glutathione peroxidase YP_186180.1 1342869 R 93062 CDS YP_186181.1 57650297 3236012 1343457..1344695 1 NC_002951.2 identified by match to protein family HMM PF04471; GTP-binding protein 1344695 3236012 SACOL1326 Staphylococcus aureus subsp. aureus COL GTP-binding protein YP_186181.1 1343457 D 93062 CDS YP_186182.1 57650298 3237273 1344714..1345952 1 NC_002951.2 identified by match to protein family HMM PF06838; hypothetical protein 1345952 3237273 SACOL1327 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186182.1 1344714 D 93062 CDS YP_186183.1 57650299 3236141 1346195..1346563 1 NC_002951.2 identified by similarity to EGAD:15799; match to protein family HMM PF00376; glutamine synthetase 1346563 glnR 3236141 glnR Staphylococcus aureus subsp. aureus COL glutamine synthetase YP_186183.1 1346195 D 93062 CDS YP_186184.1 57650300 3237965 1346582..1347922 1 NC_002951.2 identified by similarity to EGAD:102439; match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653; glutamine synthetase 1347922 femC 3237965 femC Staphylococcus aureus subsp. aureus COL glutamine synthetase YP_186184.1 1346582 D 93062 CDS YP_186185.1 57650301 3237904 1348415..1348612 1 NC_002951.2 hypothetical protein 1348612 3237904 SACOL1331 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186185.1 1348415 D 93062 CDS YP_186186.1 57650302 3237283 1349301..1349525 1 NC_002951.2 hypothetical protein 1349525 3237283 SACOL1332 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186186.1 1349301 D 93062 CDS YP_186187.1 57650303 3237882 1349819..1350025 1 NC_002951.2 hypothetical protein 1350025 3237882 SACOL1333 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186187.1 1349819 D 93062 CDS YP_186188.1 57650304 3237894 1350726..1350836 1 NC_002951.2 hypothetical protein 1350836 3237894 SACOL1334 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186188.1 1350726 D 93062 CDS YP_186189.1 57650305 3237141 1351264..1351449 1 NC_002951.2 hypothetical protein 1351449 3237141 SACOL1335 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186189.1 1351264 D 93062 CDS YP_186190.1 57650306 3237260 1351961..1352065 1 NC_002951.2 hypothetical protein 1352065 3237260 SACOL1336 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186190.1 1351961 D 93062 CDS YP_186191.1 57650307 3237695 1352098..1352193 1 NC_002951.2 hypothetical protein 1352193 3237695 SACOL1337 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186191.1 1352098 D 93062 CDS YP_186192.1 57650308 3236048 1352194..1352445 1 NC_002951.2 hypothetical protein 1352445 3236048 SACOL1338 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186192.1 1352194 D 93062 CDS YP_186193.1 57650309 3236285 1352650..1353075 1 NC_002951.2 hypothetical protein 1353075 3236285 SACOL1339 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186193.1 1352650 D 93062 CDS YP_186194.1 57650310 3237344 1353196..1353444 1 NC_002951.2 hypothetical protein 1353444 3237344 SACOL1340 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186194.1 1353196 D 93062 CDS YP_186195.1 57650311 3237056 1353574..1353675 1 NC_002951.2 hypothetical protein 1353675 3237056 SACOL1341 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186195.1 1353574 D 93062 CDS YP_186196.1 57650312 3237265 1353721..1353987 1 NC_002951.2 hypothetical protein 1353987 3237265 SACOL1342 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186196.1 1353721 D 93062 CDS YP_186197.1 57650313 3237301 1354324..1354458 1 NC_002951.2 hypothetical protein 1354458 3237301 SACOL1344 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186197.1 1354324 D 93062 CDS YP_186198.1 57650314 3237300 1354549..1354839 1 NC_002951.2 hypothetical protein 1354839 3237300 SACOL1345 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186198.1 1354549 D 93062 CDS YP_186199.1 57650315 3236116 1354850..1355044 1 NC_002951.2 hypothetical protein 1355044 3236116 SACOL1346 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186199.1 1354850 D 93062 CDS YP_186200.1 57650316 3237195 1355094..1355435 1 NC_002951.2 hypothetical protein 1355435 3237195 SACOL1347 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186200.1 1355094 D 93062 CDS YP_186201.1 57650317 3237885 1355442..1355633 1 NC_002951.2 identified by similarity to GB:AAO04588.1; hypothetical protein 1355633 3237885 SACOL1348 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186201.1 1355442 D 93062 CDS YP_186202.1 57650318 3236144 complement(1356182..1357207) 1 NC_002951.2 identified by similarity to OMNI:PG0474; hypothetical protein 1357207 3236144 SACOL1349 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186202.1 1356182 R 93062 CDS YP_186203.1 57650319 3237974 1357477..1357674 1 NC_002951.2 identified by similarity to GB:AAO04593.1; hypothetical protein 1357674 3237974 SACOL1350 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186203.1 1357477 D 93062 CDS YP_186204.1 57650320 3237976 1357732..1359213 1 NC_002951.2 identified by similarity to SP:O66043; match to protein family HMM PF00614; cardiolipin synthetase 1359213 cls1 3237976 cls1 Staphylococcus aureus subsp. aureus COL cardiolipin synthetase YP_186204.1 1357732 D 93062 CDS YP_186205.1 57650321 3237330 1359388..1360296 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1360296 3237330 SACOL1352 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_186205.1 1359388 D 93062 CDS YP_186206.1 57650322 3236077 1360265..1360996 1 NC_002951.2 ABC transporter permease 1360996 3236077 SACOL1353 Staphylococcus aureus subsp. aureus COL ABC transporter permease YP_186206.1 1360265 D 93062 CDS YP_186207.1 57650323 3236156 1361000..1362091 1 NC_002951.2 identified by match to protein family HMM PF02518; sensor histidine kinase 1362091 3236156 SACOL1354 Staphylococcus aureus subsp. aureus COL sensor histidine kinase YP_186207.1 1361000 D 93062 CDS YP_186208.1 57650324 3237166 1362088..1362690 1 NC_002951.2 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; LuxR family DNA-binding response regulator 1362690 3237166 SACOL1355 Staphylococcus aureus subsp. aureus COL LuxR family DNA-binding response regulator YP_186208.1 1362088 D 93062 CDS YP_186209.1 57650325 3237568 1362963..1363070 1 NC_002951.2 hypothetical protein 1363070 3237568 SACOL1356 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186209.1 1362963 D 93062 CDS YP_186210.1 57650326 3237703 1363130..1363663 1 NC_002951.2 identified by match to protein family HMM PF00565; thermonuclease 1363663 3237703 SACOL1357 Staphylococcus aureus subsp. aureus COL thermonuclease YP_186210.1 1363130 D 93062 CDS YP_186211.1 57650327 3237343 complement(1363806..1364660) 1 NC_002951.2 identified by similarity to GB:AAO04603.1; hypothetical protein 1364660 3237343 SACOL1358 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186211.1 1363806 R 93062 CDS YP_186212.1 57650328 3237168 1364976..1365566 1 NC_002951.2 identified by similarity to GB:AAO04604.1; hypothetical protein 1365566 3237168 SACOL1359 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186212.1 1364976 D 93062 CDS YP_186213.1 57650329 3237434 complement(1365620..1367002) 1 NC_002951.2 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 1367002 3237434 SACOL1360 Staphylococcus aureus subsp. aureus COL aspartate kinase YP_186213.1 1365620 R 93062 CDS YP_186214.1 57650330 3237161 1367008..1367115 1 NC_002951.2 hypothetical protein 1367115 3237161 SACOL1361 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186214.1 1367008 D 93062 CDS YP_186215.1 57650331 3237612 1367193..1368473 1 NC_002951.2 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1368473 hom 3237612 hom Staphylococcus aureus subsp. aureus COL homoserine dehydrogenase YP_186215.1 1367193 D 93062 CDS YP_186216.1 57650332 3236145 1368479..1369540 1 NC_002951.2 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1369540 thrC 3236145 thrC Staphylococcus aureus subsp. aureus COL threonine synthase YP_186216.1 1368479 D 93062 CDS YP_186217.1 57650333 3236142 1369542..1370456 1 NC_002951.2 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 1370456 thrB 3236142 thrB Staphylococcus aureus subsp. aureus COL homoserine kinase YP_186217.1 1369542 D 93062 CDS YP_186218.1 57650334 3237316 1370514..1371317 1 NC_002951.2 identified by match to protein family HMM PF00702; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; HAD superfamily hydrolase 1371317 3237316 SACOL1365 Staphylococcus aureus subsp. aureus COL HAD superfamily hydrolase YP_186218.1 1370514 D 93062 CDS YP_186219.1 57650335 3237329 complement(1371610..1371924) 1 NC_002951.2 identified by similarity to GB:AAO04611.1; hypothetical protein 1371924 3237329 SACOL1366 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186219.1 1371610 R 93062 CDS YP_186220.1 57650336 3237332 complement(1372142..1373596) 1 NC_002951.2 identified by match to protein family HMM PF00324; amino acid permease 1373596 3237332 SACOL1367 Staphylococcus aureus subsp. aureus COL amino acid permease YP_186220.1 1372142 R 93062 CDS YP_186221.1 57650337 3236085 1373896..1375317 1 NC_002951.2 identified by similarity to EGAD:29401; match to protein family HMM PF00199; catalase 1375317 kataA 3236085 kataA Staphylococcus aureus subsp. aureus COL catalase YP_186221.1 1373896 D 93062 CDS YP_186222.1 57650338 3237135 1375408..1375557 1 NC_002951.2 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1375557 rpmG 3237135 rpmG Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L33 YP_186222.1 1375408 D 93062 CDS YP_186223.1 57650339 3237267 1376011..1376280 1 NC_002951.2 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 1376280 rpsN 3237267 rpsN Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S14 YP_186223.1 1376011 D 93062 CDS YP_186224.1 57650340 3237315 1376437..1377414 1 NC_002951.2 identified by match to protein family HMM PF00478; match to protein family HMM TIGR01306; guanosine 5'-monophosphate oxidoreductase 1377414 guaC 3237315 guaC Staphylococcus aureus subsp. aureus COL guanosine 5'-monophosphate oxidoreductase YP_186224.1 1376437 D 93062 CDS YP_186225.1 57650341 3237704 complement(1377411..1377515) 1 NC_002951.2 hypothetical protein 1377515 3237704 SACOL1372 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186225.1 1377411 R 93062 CDS YP_186226.1 57650342 3237305 1377589..1378452 1 NC_002951.2 identified by similarity to EGAD:107961; hypothetical protein 1378452 3237305 SACOL1373 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186226.1 1377589 D 93062 CDS YP_186227.1 57650343 3237666 complement(1378832..1379455) 1 NC_002951.2 Represses a number of genes involved in the response to DNA damage; LexA repressor 1379455 lexA 3237666 lexA Staphylococcus aureus subsp. aureus COL LexA repressor YP_186227.1 1378832 R 93062 CDS YP_186228.1 57650344 3237325 1379598..1379831 1 NC_002951.2 identified by similarity to GB:AAO04620.1; hypothetical protein 1379831 3237325 SACOL1375 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186228.1 1379598 D 93062 CDS YP_186229.1 57650345 3237534 1379967..1380206 1 NC_002951.2 identified by similarity to OMNI:NTL01SPL1328; match to protein family HMM PF05979; hypothetical protein 1380206 3237534 SACOL1376 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186229.1 1379967 D 93062 CDS YP_186230.1 57650346 3237261 1380327..1382315 1 NC_002951.2 identified by similarity to EGAD:29878; match to protein family HMM PF00456; match to protein family HMM PF02779; match to protein family HMM PF02780; match to protein family HMM TIGR00232; transketolase 1382315 tkt 3237261 tkt Staphylococcus aureus subsp. aureus COL transketolase YP_186230.1 1380327 D 93062 CDS YP_186231.1 57650347 3236094 1382593..1382835 1 NC_002951.2 identified by similarity to SP:Q8CSP3; match to protein family HMM PF03672; hypothetical protein 1382835 3236094 SACOL1378 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186231.1 1382593 D 93062 CDS YP_186232.1 57650348 3237337 1382822..1382920 1 NC_002951.2 hypothetical protein 1382920 3237337 SACOL1379 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186232.1 1382822 D 93062 CDS YP_186233.1 57650349 3236269 1383014..1383481 1 NC_002951.2 identified by similarity to EGAD:29885; match to protein family HMM PF07301; hypothetical protein 1383481 3236269 SACOL1380 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186233.1 1383014 D 93062 CDS YP_186234.1 57650350 3236271 1383605..1384726 1 NC_002951.2 identified by similarity to EGAD:9310; match to protein family HMM PF00149; match to protein family HMM TIGR00619; exonuclease SbcD 1384726 sbcD 3236271 sbcD Staphylococcus aureus subsp. aureus COL exonuclease SbcD YP_186234.1 1383605 D 93062 CDS YP_186235.1 57650351 3237143 1384730..1387759 1 NC_002951.2 identified by similarity to EGAD:7288; exonuclease SbcC 1387759 sbcC 3237143 sbcC Staphylococcus aureus subsp. aureus COL exonuclease SbcC YP_186235.1 1384730 D 93062 CDS YP_186236.1 57650352 3237602 complement(1387830..1388192) 1 NC_002951.2 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 1388192 mscL 3237602 mscL Staphylococcus aureus subsp. aureus COL large-conductance mechanosensitive channel YP_186236.1 1387830 R 93062 CDS YP_186237.1 57650353 3238581 1388396..1390042 1 NC_002951.2 identified by similarity to EGAD:45763; match to protein family HMM PF02028; match to protein family HMM TIGR00842; BCCT family osmoprotectant transporter 1390042 opuD1 3238581 opuD1 Staphylococcus aureus subsp. aureus COL BCCT family osmoprotectant transporter YP_186237.1 1388396 D 93062 CDS YP_186238.1 57650354 3238094 1390934..1393639 1 NC_002951.2 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1393639 acnA 3238094 acnA Staphylococcus aureus subsp. aureus COL aconitate hydratase YP_186238.1 1390934 D 93062 CDS YP_186239.1 57650355 3238136 1393819..1394286 1 NC_002951.2 identified by similarity to GP:10174908; match to protein family HMM PF03061; match to protein family HMM TIGR00051; hypothetical protein 1394286 3238136 SACOL1386 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186239.1 1393819 D 93062 CDS YP_186240.1 57650356 3238038 complement(1394493..1394789) 1 NC_002951.2 identified by similarity to EGAD:109071; match to protein family HMM PF07113; hypothetical protein 1394789 3238038 SACOL1387 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186240.1 1394493 R 93062 CDS YP_186241.1 57650357 3237152 complement(1395165..1395773) 1 NC_002951.2 identified by match to protein family HMM PF02660; match to protein family HMM TIGR00023; hypothetical protein 1395773 3237152 SACOL1388 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186241.1 1395165 R 93062 CDS YP_186242.1 57650358 3236245 1395973..1397970 1 NC_002951.2 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1397970 parE 3236245 parE Staphylococcus aureus subsp. aureus COL DNA topoisomerase IV subunit B YP_186242.1 1395973 D 93062 CDS YP_186243.1 57650359 3237159 1397970..1400372 1 NC_002951.2 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1400372 parC 3237159 parC Staphylococcus aureus subsp. aureus COL DNA topoisomerase IV subunit A YP_186243.1 1397970 D 93062 CDS YP_186244.1 57650360 3236127 1400622..1402097 1 NC_002951.2 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835; sodium:alanine symporter family protein 1402097 3236127 SACOL1392 Staphylococcus aureus subsp. aureus COL sodium:alanine symporter family protein YP_186244.1 1400622 D 93062 CDS YP_186245.1 57650361 3236319 1402582..1403433 1 NC_002951.2 identified by similarity to SP:P39805; match to protein family HMM PF00874; match to protein family HMM PF03123; transcription antiterminator 1403433 3236319 SACOL1393 Staphylococcus aureus subsp. aureus COL transcription antiterminator YP_186245.1 1402582 D 93062 CDS YP_186246.1 57650362 3237562 1403408..1403575 1 NC_002951.2 hypothetical protein 1403575 3237562 SACOL1394 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186246.1 1403408 D 93062 CDS YP_186247.1 57650363 3237576 1403568..1404776 1 NC_002951.2 identified by similarity to EGAD:108679; match to protein family HMM PF01594; hypothetical protein 1404776 3237576 SACOL1395 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186247.1 1403568 D 93062 CDS YP_186248.1 57650364 3237597 1405257..1407779 1 NC_002951.2 identified by match to protein family HMM PF04329; match to protein family HMM PF04330; match to protein family HMM PF04331; fmtC protein 1407779 fmtC 3237597 fmtC Staphylococcus aureus subsp. aureus COL fmtC protein YP_186248.1 1405257 D 93062 CDS YP_186249.1 57650365 3237919 complement(1407982..1408491) 1 NC_002951.2 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 1408491 msrA 3237919 msrA Staphylococcus aureus subsp. aureus COL methionine sulfoxide reductase A YP_186249.1 1407982 R 93062 CDS YP_186250.1 57650366 3237702 1408628..1409611 1 NC_002951.2 identified by similarity to EGAD:20070; match to protein family HMM PF03816; match to protein family HMM TIGR00350; transcriptional regulator 1409611 3237702 SACOL1398 Staphylococcus aureus subsp. aureus COL transcriptional regulator YP_186250.1 1408628 D 93062 CDS YP_186251.1 57650367 3236692 complement(1409699..1409884) 1 NC_002951.2 identified by match to protein family HMM PF01361; match to protein family HMM TIGR00013; 4-oxalocrotonate tautomerase 1409884 dmpI 3236692 dmpI Staphylococcus aureus subsp. aureus COL 4-oxalocrotonate tautomerase YP_186251.1 1409699 R 93062 CDS YP_186252.1 57650368 3236153 1410032..1411294 1 NC_002951.2 identified by match to protein family HMM PF00817; ImpB/MucB/SamB family protein 1411294 3236153 SACOL1400 Staphylococcus aureus subsp. aureus COL ImpB/MucB/SamB family protein YP_186252.1 1410032 D 93062 CDS YP_186253.1 57650369 3236275 complement(1411431..1412522) 1 NC_002951.2 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 1412522 tyrA 3236275 tyrA Staphylococcus aureus subsp. aureus COL prephenate dehydrogenase YP_186253.1 1411431 R 93062 CDS YP_186254.1 57650370 3237834 1412687..1413718 1 NC_002951.2 identified by similarity to EGAD:108848; match to protein family HMM PF05343; glutamyl aminopeptidase 1413718 3237834 SACOL1402 Staphylococcus aureus subsp. aureus COL glutamyl aminopeptidase YP_186254.1 1412687 D 93062 CDS YP_186255.1 57650371 3236120 1414210..1415616 1 NC_002951.2 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1415616 trpE 3236120 trpE Staphylococcus aureus subsp. aureus COL anthranilate synthase component I YP_186255.1 1414210 D 93062 CDS YP_186256.1 57650372 3236143 1415613..1416179 1 NC_002951.2 identified by similarity to SP:Q02003; match to protein family HMM PF00117; match to protein family HMM TIGR00566; anthranilate synthase component II 1416179 trpG 3236143 trpG Staphylococcus aureus subsp. aureus COL anthranilate synthase component II YP_186256.1 1415613 D 93062 CDS YP_186257.1 57650373 3237298 1416185..1417183 1 NC_002951.2 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1417183 trpD 3237298 trpD Staphylococcus aureus subsp. aureus COL anthranilate phosphoribosyltransferase YP_186257.1 1416185 D 93062 CDS YP_186258.1 57650374 3237335 1417185..1417967 1 NC_002951.2 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase 1417967 trpC 3237335 trpC Staphylococcus aureus subsp. aureus COL indole-3-glycerol-phosphate synthase YP_186258.1 1417185 D 93062 CDS YP_186259.1 57650375 3237862 1417964..1418599 1 NC_002951.2 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase 1418599 trpF 3237862 trpF Staphylococcus aureus subsp. aureus COL N-(5'-phosphoribosyl)anthranilate isomerase YP_186259.1 1417964 D 93062 CDS YP_186260.1 57650376 3237588 1418592..1419806 1 NC_002951.2 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1419806 trpB 3237588 trpB Staphylococcus aureus subsp. aureus COL tryptophan synthase subunit beta YP_186260.1 1418592 D 93062 CDS YP_186261.1 57650377 3237599 1419799..1420527 1 NC_002951.2 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1420527 trpA 3237599 trpA Staphylococcus aureus subsp. aureus COL tryptophan synthase subunit alpha YP_186261.1 1419799 D 93062 CDS YP_186262.1 57651875 3236169 1420810..1422111 1 NC_002951.2 identified by similarity to EGAD:29547; match to protein family HMM PF02388; femA protein 1422111 femA 3236169 femA Staphylococcus aureus subsp. aureus COL femA protein YP_186262.1 1420810 D 93062 CDS YP_186263.1 57651876 3236170 1422130..1423389 1 NC_002951.2 identified by similarity to EGAD:29548; match to protein family HMM PF02388; femB protein 1423389 3236170 SACOL1411 Staphylococcus aureus subsp. aureus COL femB protein YP_186263.1 1422130 D 93062 CDS YP_186264.1 57651877 3236171 1424072..1424839 1 NC_002951.2 identified by match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; hydrolase-like protein 1424839 3236171 SACOL1412 Staphylococcus aureus subsp. aureus COL hydrolase-like protein YP_186264.1 1424072 D 93062 CDS YP_186265.1 57651878 3236172 complement(1424887..1425360) 1 NC_002951.2 hypothetical protein 1425360 3236172 SACOL1413 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186265.1 1424887 R 93062 CDS YP_186266.1 57651879 3236173 complement(1425484..1426185) 1 NC_002951.2 identified by match to protein family HMM PF00005; peptide ABC transporter ATP-binding protein 1426185 3236173 SACOL1414 Staphylococcus aureus subsp. aureus COL peptide ABC transporter ATP-binding protein YP_186266.1 1425484 R 93062 CDS YP_186267.1 57651880 3236562 complement(1426178..1426951) 1 NC_002951.2 identified by match to protein family HMM PF00005; peptide ABC transporter ATP-binding protein 1426951 3236562 SACOL1415 Staphylococcus aureus subsp. aureus COL peptide ABC transporter ATP-binding protein YP_186267.1 1426178 R 93062 CDS YP_186268.1 57651881 3236563 complement(1426938..1427768) 1 NC_002951.2 identified by match to protein family HMM PF00528; peptide ABC transporter permease 1427768 3236563 SACOL1416 Staphylococcus aureus subsp. aureus COL peptide ABC transporter permease YP_186268.1 1426938 R 93062 CDS YP_186269.1 57651882 3236564 complement(1427761..1428747) 1 NC_002951.2 identified by match to protein family HMM PF00528; peptide ABC transporter permease 1428747 3236564 SACOL1417 Staphylococcus aureus subsp. aureus COL peptide ABC transporter permease YP_186269.1 1427761 R 93062 CDS YP_186270.1 57651883 3236565 complement(1429051..1429395) 1 NC_002951.2 identified by similarity to GB:AAO04661.1; hypothetical protein 1429395 3236565 SACOL1418 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186270.1 1429051 R 93062 CDS YP_186271.1 57651884 3236566 1429600..1431414 1 NC_002951.2 identified by match to protein family HMM PF01432; match to protein family HMM TIGR00181; oligoendopeptidase F 1431414 3236566 SACOL1419 Staphylococcus aureus subsp. aureus COL oligoendopeptidase F YP_186271.1 1429600 D 93062 CDS YP_186272.1 57651885 3236567 complement(1431554..1432195) 1 NC_002951.2 identified by match to protein family HMM PF01895; match to protein family HMM TIGR02135; phosphate transport system protein PhoU 1432195 3236567 SACOL1420 Staphylococcus aureus subsp. aureus COL phosphate transport system protein PhoU YP_186272.1 1431554 R 93062 CDS YP_186273.1 57651886 3236568 complement(1432202..1433053) 1 NC_002951.2 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1433053 3236568 SACOL1421 Staphylococcus aureus subsp. aureus COL phosphate transporter ATP-binding protein YP_186273.1 1432202 R 93062 CDS YP_186274.1 57651887 3236371 complement(1433100..1434017) 1 NC_002951.2 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; phosphate ABC transporter permease 1434017 3236371 SACOL1422 Staphylococcus aureus subsp. aureus COL phosphate ABC transporter permease YP_186274.1 1433100 R 93062 CDS YP_186275.1 57651888 3236372 complement(1434019..1434945) 1 NC_002951.2 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138; phosphate ABC transporter permease 1434945 3236372 SACOL1423 Staphylococcus aureus subsp. aureus COL phosphate ABC transporter permease YP_186275.1 1434019 R 93062 CDS YP_186276.1 57651889 3236373 complement(1435136..1436119) 1 NC_002951.2 identified by match to protein family HMM PF01547; match to protein family HMM TIGR02136; phosphate ABC transporter substrate-binding protein 1436119 3236373 SACOL1424 Staphylococcus aureus subsp. aureus COL phosphate ABC transporter substrate-binding protein YP_186276.1 1435136 R 93062 CDS YP_186277.1 57651890 3236374 1436659..1436955 1 NC_002951.2 identified by similarity to GP:8918792; truncated IS1272 transposase 1436955 3236374 SACOL1425 Staphylococcus aureus subsp. aureus COL truncated IS1272 transposase YP_186277.1 1436659 D 93062 CDS YP_186278.1 57651891 3236375 complement(1437091..1437993) 1 NC_002951.2 identified by similarity to EGAD:107281; hypothetical protein 1437993 3236375 SACOL1426 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186278.1 1437091 R 93062 CDS YP_186279.1 57651892 3236376 1438140..1439741 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1439741 3236376 SACOL1427 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_186279.1 1438140 D 93062 CDS YP_186280.1 57651893 3236208 1440601..1441806 1 NC_002951.2 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1441806 lysC 3236208 lysC Staphylococcus aureus subsp. aureus COL aspartate kinase YP_186280.1 1440601 D 93062 CDS YP_186281.1 57651894 3236209 1441870..1442859 1 NC_002951.2 identified by similarity to EGAD:15165; match to protein family HMM PF01118; match to protein family HMM PF02774; match to protein family HMM TIGR01296; aspartate semialdehyde dehydrogenase 1442859 asd 3236209 asd Staphylococcus aureus subsp. aureus COL aspartate semialdehyde dehydrogenase YP_186281.1 1441870 D 93062 CDS YP_186282.1 57651895 3236210 1442861..1443748 1 NC_002951.2 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1443748 dapA 3236210 dapA Staphylococcus aureus subsp. aureus COL dihydrodipicolinate synthase YP_186282.1 1442861 D 93062 CDS YP_186283.1 57651896 3236211 1443745..1444467 1 NC_002951.2 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1444467 dapB 3236211 dapB Staphylococcus aureus subsp. aureus COL dihydrodipicolinate reductase YP_186283.1 1443745 D 93062 CDS YP_186284.1 57651897 3236212 1444494..1445213 1 NC_002951.2 identified by similarity to EGAD:165602; match to protein family HMM PF00132; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 1445213 dapD 3236212 dapD Staphylococcus aureus subsp. aureus COL 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase YP_186284.1 1444494 D 93062 CDS YP_186285.1 57651898 3236553 1445356..1446507 1 NC_002951.2 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; M20/M25/M40 family peptidase 1446507 3236553 SACOL1433 Staphylococcus aureus subsp. aureus COL M20/M25/M40 family peptidase YP_186285.1 1445356 D 93062 CDS YP_186286.1 57651899 3236554 1446512..1447597 1 NC_002951.2 identified by match to protein family HMM PF00842; match to protein family HMM PF01168; alanine racemase 1447597 3236554 SACOL1434 Staphylococcus aureus subsp. aureus COL alanine racemase YP_186286.1 1446512 D 93062 CDS YP_186287.1 57651900 3236555 1447587..1448852 1 NC_002951.2 identified by similarity to SP:P23630; match to protein family HMM PF00278; match to protein family HMM PF02784; match to protein family HMM TIGR01048; diaminopimelate decarboxylase 1448852 lysA 3236555 lysA Staphylococcus aureus subsp. aureus COL diaminopimelate decarboxylase YP_186287.1 1447587 D 93062 CDS YP_186288.1 57651901 3236556 complement(1449092..1449493) 1 NC_002951.2 hypothetical protein 1449493 3236556 SACOL1436 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186288.1 1449092 R 93062 CDS YP_186289.1 57651902 3236557 complement(1449690..1449890) 1 NC_002951.2 identified by match to protein family HMM PF00313; CSD family cold shock protein 1449890 3236557 SACOL1437 Staphylococcus aureus subsp. aureus COL CSD family cold shock protein YP_186289.1 1449690 R 93062 CDS YP_186290.1 57651903 3236558 complement(1450061..1450369) 1 NC_002951.2 identified by similarity to OMNI:EF2065; match to protein family HMM PF06279; hypothetical protein 1450369 3236558 SACOL1438 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186290.1 1450061 R 93062 CDS YP_186291.1 57651904 3236547 1450532..1450801 1 NC_002951.2 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1450801 3236547 SACOL1439 Staphylococcus aureus subsp. aureus COL acylphosphatase YP_186291.1 1450532 D 93062 CDS YP_186292.1 57651905 3236548 1450820..1451449 1 NC_002951.2 identified by similarity to EGAD:19663; hypothetical protein 1451449 3236548 SACOL1440 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186292.1 1450820 D 93062 CDS YP_186293.1 57651906 3236549 1451481..1452617 1 NC_002951.2 identified by similarity to EGAD:143199; match to protein family HMM PF05816; tellurite resistance protein 1452617 3236549 SACOL1441 Staphylococcus aureus subsp. aureus COL tellurite resistance protein YP_186293.1 1451481 D 93062 CDS YP_186295.1 57651908 3236551 complement(1453630..1454973) 1 NC_002951.2 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796; branched-chain amino acid transport system II carrier protein 1454973 brnQ3 3236551 brnQ3 Staphylococcus aureus subsp. aureus COL branched-chain amino acid transport system II carrier protein YP_186295.1 1453630 R 93062 CDS YP_186296.1 57651909 3236552 complement(1455198..1457084) 1 NC_002951.2 identified by similarity to EGAD:109250; hypothetical protein 1457084 3236552 SACOL1444 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186296.1 1455198 R 93062 CDS YP_186297.1 57651910 3238280 complement(1457098..1457889) 1 NC_002951.2 identified by similarity to EGAD:42972; CbbQ/NirQ/NorQ/GpvN family protein 1457889 3238280 SACOL1445 Staphylococcus aureus subsp. aureus COL CbbQ/NirQ/NorQ/GpvN family protein YP_186297.1 1457098 R 93062 CDS YP_186298.1 57651911 3238281 complement(1458070..1458273) 1 NC_002951.2 identified by similarity to GP:10174822; hypothetical protein 1458273 3238281 SACOL1446 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186298.1 1458070 R 93062 CDS YP_186299.1 57651912 3238282 complement(1458302..1459111) 1 NC_002951.2 identified by similarity to GP:10174794; hypothetical protein 1459111 3238282 SACOL1447 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186299.1 1458302 R 93062 CDS YP_186300.1 57651913 3238283 complement(1459691..1460959) 1 NC_002951.2 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 1460959 sucB 3238283 sucB Staphylococcus aureus subsp. aureus COL dihydrolipoamide succinyltransferase YP_186300.1 1459691 R 93062 CDS YP_186301.1 57651914 3238284 complement(1460973..1463771) 1 NC_002951.2 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 1463771 sucA 3238284 sucA Staphylococcus aureus subsp. aureus COL 2-oxoglutarate dehydrogenase E1 component YP_186301.1 1460973 R 93062 CDS YP_186302.1 57651915 3238285 complement(1464055..1465410) 1 NC_002951.2 identified by similarity to GP:9230553; similarity to OMNI:SA1450; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase ArlS 1465410 arlS 3238285 arlS Staphylococcus aureus subsp. aureus COL sensor histidine kinase ArlS YP_186302.1 1464055 R 93062 CDS YP_186303.1 57651916 3238224 complement(1465407..1466066) 1 NC_002951.2 identified by similarity to GP:9230552; similarity to OMNI:SA1451; match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator ArlR 1466066 arlR 3238224 arlR Staphylococcus aureus subsp. aureus COL DNA-binding response regulator ArlR YP_186303.1 1465407 R 93062 CDS YP_186304.1 57651917 3238225 complement(1466854..1467468) 1 NC_002951.2 identified by match to protein family HMM PF01569; hypothetical protein 1467468 3238225 SACOL1452 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186304.1 1466854 R 93062 CDS YP_186305.1 57651918 3238226 complement(1467485..1468555) 1 NC_002951.2 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDPdiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1468555 murG 3238226 murG Staphylococcus aureus subsp. aureus COL UDPdiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_186305.1 1467485 R 93062 CDS YP_186306.1 57650378 3238127 complement(1469477..1470967) 1 NC_002951.2 identified by match to protein family HMM PF00595; match to protein family HMM PF03572; match to protein family HMM TIGR00225; carboxyl-terminal protease 1470967 3238127 SACOL1455 Staphylococcus aureus subsp. aureus COL carboxyl-terminal protease YP_186306.1 1469477 R 93062 CDS YP_186307.1 57650379 3238072 complement(1471159..1471380) 1 NC_002951.2 identified by similarity to OMNI:EF1680; match to protein family HMM PF06855; hypothetical protein 1471380 3238072 SACOL1456 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186307.1 1471159 R 93062 CDS YP_186308.1 57650380 3238636 complement(1471380..1471880) 1 NC_002951.2 identified by match to protein family HMM PF00358; match to protein family HMM TIGR00830; PTS system, IIA component 1471880 3238636 SACOL1457 Staphylococcus aureus subsp. aureus COL PTS system, IIA component YP_186308.1 1471380 R 93062 CDS YP_186309.1 57650381 3238616 complement(1472932..1473771) 1 NC_002951.2 identified by match to protein family HMM PF02645; match to protein family HMM TIGR00762; hypothetical protein 1473771 3238616 SACOL1460 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186309.1 1472932 R 93062 CDS YP_186310.1 57650382 3238319 complement(1473786..1474265) 1 NC_002951.2 identified by similarity to SP:P10167; match to protein family HMM PF00186; dihydrofolate reductase 1474265 folA 3238319 folA Staphylococcus aureus subsp. aureus COL dihydrofolate reductase YP_186310.1 1473786 R 93062 CDS YP_186311.1 57650383 3238178 complement(1474465..1475421) 1 NC_002951.2 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1475421 thyA 3238178 thyA Staphylococcus aureus subsp. aureus COL thymidylate synthase YP_186311.1 1474465 R 93062 CDS YP_186312.1 57650384 3238106 complement(1475845..1476282) 1 NC_002951.2 identified by similarity to EGAD:45736; match to protein family HMM PF06491; hypothetical protein 1476282 3238106 SACOL1464 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186312.1 1475845 R 93062 CDS YP_186313.1 57650385 3238354 complement(1476298..1477422) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH1721; match to protein family HMM PF03130; hypothetical protein 1477422 3238354 SACOL1465 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186313.1 1476298 R 93062 CDS YP_186314.1 57650386 3238370 complement(1477460..1477711) 1 NC_002951.2 identified by similarity to GP:5738608; hypothetical protein 1477711 3238370 SACOL1466 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186314.1 1477460 R 93062 CDS YP_186315.1 57650387 3237581 complement(1477723..1477917) 1 NC_002951.2 identified by similarity to EGAD:45731; hypothetical protein 1477917 3237581 SACOL1467 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186315.1 1477723 R 93062 CDS YP_186316.1 57650388 3237598 1478162..1478866 1 NC_002951.2 identified by match to protein family HMM PF02592; match to protein family HMM TIGR00697; hypothetical protein 1478866 3237598 SACOL1468 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186316.1 1478162 D 93062 CDS YP_186317.1 57650389 3237993 complement(1478931..1479062) 1 NC_002951.2 hypothetical protein 1479062 3237993 SACOL1469 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186317.1 1478931 R 93062 CDS YP_186318.1 57650390 3237553 1479407..1479808 1 NC_002951.2 identified by match to protein family HMM PF00075; cell wall enzyme EbsB 1479808 3237553 SACOL1471 Staphylococcus aureus subsp. aureus COL cell wall enzyme EbsB YP_186318.1 1479407 D 93062 CDS YP_186319.1 57651379 3237115 complement(1479867..1511363) 1 NC_002951.2 identified by match to protein family HMM PF01468; match to protein family HMM PF04650; match to protein family HMM PF07554; match to protein family HMM PF07564; match to protein family HMM TIGR01168; match to protein family HMM TIGR01643; cell wall associated fibronectin-binding protein 1511363 ebh 3237115 ebh Staphylococcus aureus subsp. aureus COL cell wall associated fibronectin-binding protein YP_186319.1 1479867 R 93062 CDS YP_186320.1 57650391 3238491 complement(1511761..1513152) 1 NC_002951.2 identified by match to protein family HMM PF07690; drug transporter 1513152 3238491 SACOL1475 Staphylococcus aureus subsp. aureus COL drug transporter YP_186320.1 1511761 R 93062 CDS YP_186321.1 57650392 3237275 complement(1513309..1514631) 1 NC_002951.2 identified by match to protein family HMM PF00324; amino acid permease 1514631 3237275 SACOL1476 Staphylococcus aureus subsp. aureus COL amino acid permease YP_186321.1 1513309 R 93062 CDS YP_186322.1 57650393 3236081 complement(1514662..1515702) 1 NC_002951.2 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase 1515702 ilvA1 3236081 ilvA1 Staphylococcus aureus subsp. aureus COL threonine dehydratase YP_186322.1 1514662 R 93062 CDS YP_186323.1 57650394 3237750 complement(1515797..1516915) 1 NC_002951.2 identified by match to protein family HMM PF01262; match to protein family HMM PF05222; match to protein family HMM TIGR00518; alanine dehydrogenase 1516915 ald1 3237750 ald1 Staphylococcus aureus subsp. aureus COL alanine dehydrogenase YP_186323.1 1515797 R 93062 CDS YP_186324.1 57650395 3237691 complement(1517390..1518268) 1 NC_002951.2 identified by match to protein family HMM PF01367; match to protein family HMM PF02739; 5'-3' exonuclease 1518268 3237691 SACOL1479 Staphylococcus aureus subsp. aureus COL 5'-3' exonuclease YP_186324.1 1517390 R 93062 CDS YP_186325.1 57650396 3238626 complement(1518288..1521728) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH1703; hypothetical protein 1521728 3238626 SACOL1480 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186325.1 1518288 R 93062 CDS YP_186326.1 57650397 3237933 1522032..1523372 1 NC_002951.2 identified by similarity to OMNI:NTL01BH1857; match to protein family HMM PF03413; match to protein family HMM PF03929; hypothetical protein 1523372 3237933 SACOL1481 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186326.1 1522032 D 93062 CDS YP_186327.1 57650398 3236284 complement(1523578..1523910) 1 NC_002951.2 hypothetical protein 1523910 3236284 SACOL1482 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186327.1 1523578 R 93062 CDS YP_186328.1 57650399 3237809 complement(1523994..1525139) 1 NC_002951.2 identified by similarity to EGAD:37711; match to protein family HMM PF01170; hypothetical protein 1525139 3237809 SACOL1483 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186328.1 1523994 R 93062 CDS YP_186329.1 57650400 3236286 complement(1525790..1526134) 1 NC_002951.2 identified by match to protein family HMM PF05103; hypothetical protein 1526134 3236286 SACOL1484 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186329.1 1525790 R 93062 CDS YP_186330.1 57650401 3237411 complement(1526148..1526711) 1 NC_002951.2 identified by similarity to EGAD:37709; match to protein family HMM PF06908; hypothetical protein 1526711 3237411 SACOL1485 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186330.1 1526148 R 93062 CDS YP_186331.1 57650402 3237555 complement(1526704..1527054) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH1710; hypothetical protein 1527054 3237555 SACOL1486 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186331.1 1526704 R 93062 CDS YP_186332.1 57650403 3237554 1527488..1527613 1 NC_002951.2 hypothetical protein 1527613 3237554 SACOL1488 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186332.1 1527488 D 93062 CDS YP_186333.1 57650404 3237565 1527594..1528220 1 NC_002951.2 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 1528220 recU 3237565 recU Staphylococcus aureus subsp. aureus COL Holliday junction-specific endonuclease YP_186333.1 1527594 D 93062 CDS YP_186334.1 57650405 3237601 1528217..1530400 1 NC_002951.2 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; penicillin-binding protein 2 1530400 pbp2 3237601 pbp2 Staphylococcus aureus subsp. aureus COL penicillin-binding protein 2 YP_186334.1 1528217 D 93062 CDS YP_186335.1 57650406 3237940 complement(1530966..1531307) 1 NC_002951.2 identified by similarity to GB:AAO04736.1; hypothetical protein 1531307 3237940 SACOL1491 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186335.1 1530966 R 93062 CDS YP_186336.1 57650407 3237971 complement(1531312..1531971) 1 NC_002951.2 identified by similarity to EGAD:18451; match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01083; endonuclease III 1531971 nth 3237971 nth Staphylococcus aureus subsp. aureus COL endonuclease III YP_186336.1 1531312 R 93062 CDS YP_186337.1 57650408 3237994 complement(1531961..1532647) 1 NC_002951.2 identified by similarity to EGAD:16577; match to protein family HMM PF04271; match to protein family HMM TIGR01446; DNA replication protein DnaD 1532647 3237994 SACOL1493 Staphylococcus aureus subsp. aureus COL DNA replication protein DnaD YP_186337.1 1531961 R 93062 CDS YP_186338.1 57650409 3237887 complement(1532975..1534267) 1 NC_002951.2 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1534267 asnC 3237887 asnC Staphylococcus aureus subsp. aureus COL asparaginyl-tRNA synthetase YP_186338.1 1532975 R 93062 CDS YP_186339.1 57650410 3237709 complement(1534589..1537282) 1 NC_002951.2 identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573; match to protein family HMM TIGR01407; DNA polymerase III subunit epsilon/ATP-dependent helicase DinG 1537282 3237709 SACOL1495 Staphylococcus aureus subsp. aureus COL DNA polymerase III subunit epsilon/ATP-dependent helicase DinG YP_186339.1 1534589 R 93062 CDS YP_186340.1 57650411 3237611 complement(1537306..1538277) 1 NC_002951.2 identified by similarity to EGAD:30996; match to protein family HMM PF03099; match to protein family HMM TIGR00121; birA bifunctional protein 1538277 birA 3237611 birA Staphylococcus aureus subsp. aureus COL birA bifunctional protein YP_186340.1 1537306 R 93062 CDS YP_186341.1 57650412 3237288 complement(1538264..1539466) 1 NC_002951.2 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 1539466 papS 3237288 papS Staphylococcus aureus subsp. aureus COL tRNA CCA-pyrophosphorylase YP_186341.1 1538264 R 93062 CDS YP_186342.1 57650413 3237811 complement(1539471..1540625) 1 NC_002951.2 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein 1540625 3237811 SACOL1498 Staphylococcus aureus subsp. aureus COL glycosyl transferase, group 1 family protein YP_186342.1 1539471 R 93062 CDS YP_186343.1 57650414 3237635 complement(1540854..1541171) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH1682; match to protein family HMM PF03819; hypothetical protein 1541171 3237635 SACOL1499 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186343.1 1540854 R 93062 CDS YP_186344.1 57650415 3237634 complement(1541508..1542215) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH1680; match to protein family HMM PF04298; hypothetical protein 1542215 3237634 SACOL1500 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186344.1 1541508 R 93062 CDS YP_186345.1 57650416 3237644 complement(1542260..1542847) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH1678; match to protein family HMM PF07187; hypothetical protein 1542847 3237644 SACOL1501 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186345.1 1542260 R 93062 CDS YP_186346.1 57650417 3237956 complement(1542837..1543412) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH1673; hypothetical protein 1543412 3237956 SACOL1502 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186346.1 1542837 R 93062 CDS YP_186347.1 57650418 3237707 complement(1543426..1544670) 1 NC_002951.2 identified by similarity to EGAD:37740; hypothetical protein 1544670 3237707 SACOL1503 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186347.1 1543426 R 93062 CDS YP_186348.1 57650419 3237694 complement(1544677..1545975) 1 NC_002951.2 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1545975 aroA 3237694 aroA Staphylococcus aureus subsp. aureus COL 3-phosphoshikimate 1-carboxyvinyltransferase YP_186348.1 1544677 R 93062 CDS YP_186349.1 57650420 3237570 complement(1545985..1547049) 1 NC_002951.2 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1547049 aroB 3237570 aroB Staphylococcus aureus subsp. aureus COL 3-dehydroquinate synthase YP_186349.1 1545985 R 93062 CDS YP_186350.1 57650421 3237903 complement(1547075..1548241) 1 NC_002951.2 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1548241 aroC 3237903 aroC Staphylococcus aureus subsp. aureus COL chorismate synthase YP_186350.1 1547075 R 93062 CDS YP_186351.1 57650422 3237575 complement(1548627..1548827) 1 NC_002951.2 hypothetical protein 1548827 3237575 SACOL1507 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186351.1 1548627 R 93062 CDS YP_186352.1 57650423 3237808 complement(1548856..1548981) 1 NC_002951.2 hypothetical protein 1548981 3237808 SACOL1508 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186352.1 1548856 R 93062 CDS YP_186353.1 57650424 3237884 complement(1549036..1549485) 1 NC_002951.2 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1549485 ndk 3237884 ndk Staphylococcus aureus subsp. aureus COL nucleoside diphosphate kinase YP_186353.1 1549036 R 93062 CDS YP_186354.1 57650425 3237812 complement(1549577..1550536) 1 NC_002951.2 identified by similarity to EGAD:97466; match to protein family HMM PF00348; polyprenyl synthetase 1550536 3237812 SACOL1510 Staphylococcus aureus subsp. aureus COL polyprenyl synthetase YP_186354.1 1549577 R 93062 CDS YP_186355.1 57650426 3237587 complement(1550538..1551263) 1 NC_002951.2 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 1551263 ubiE 3237587 ubiE Staphylococcus aureus subsp. aureus COL ubiquinone/menaquinone biosynthesis methyltransferase YP_186355.1 1550538 R 93062 CDS YP_186356.1 57650427 3237620 complement(1551266..1551838) 1 NC_002951.2 identified by similarity to GB:AAO04756.1; hypothetical protein 1551838 3237620 SACOL1512 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186356.1 1551266 R 93062 CDS YP_186357.1 57650428 3237552 complement(1552269..1552541) 1 NC_002951.2 identified by similarity to EGAD:8587; match to protein family HMM PF00216; DNA-binding protein HU 1552541 hup 3237552 hup Staphylococcus aureus subsp. aureus COL DNA-binding protein HU YP_186357.1 1552269 R 93062 CDS YP_186358.1 57650429 3237596 complement(1552712..1553710) 1 NC_002951.2 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1553710 gpsA 3237596 gpsA Staphylococcus aureus subsp. aureus COL NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_186358.1 1552712 R 93062 CDS YP_186359.1 57650430 3237585 complement(1553727..1555037) 1 NC_002951.2 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1555037 engA 3237585 engA Staphylococcus aureus subsp. aureus COL GTP-binding protein EngA YP_186359.1 1553727 R 93062 CDS YP_186360.1 57650431 3237339 complement(1555259..1556434) 1 NC_002951.2 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1556434 rpsA 3237339 rpsA Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S1 YP_186360.1 1555259 R 93062 CDS YP_186361.1 57650432 3237910 complement(1557146..1557805) 1 NC_002951.2 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1557805 cmk 3237910 cmk Staphylococcus aureus subsp. aureus COL cytidylate kinase YP_186361.1 1557146 R 93062 CDS YP_186362.1 57650433 3237586 1557882..1558850 1 NC_002951.2 identified by similarity to EGAD:8552; match to protein family HMM PF00710; L-asparaginase 1558850 ansA 3237586 ansA Staphylococcus aureus subsp. aureus COL L-asparaginase YP_186362.1 1557882 D 93062 CDS YP_186363.1 57650434 3237980 complement(1558965..1559951) 1 NC_002951.2 identified by match to protein family HMM PF00070; pyridine nucleotide-disulfide oxidoreductase 1559951 3237980 SACOL1520 Staphylococcus aureus subsp. aureus COL pyridine nucleotide-disulfide oxidoreductase YP_186363.1 1558965 R 93062 CDS YP_186364.1 57650435 3237551 complement(1560112..1560228) 1 NC_002951.2 hypothetical protein 1560228 3237551 SACOL1521 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186364.1 1560112 R 93062 CDS YP_186365.1 57650436 3237648 complement(1560353..1561813) 1 NC_002951.2 identified by similarity to GP:1397239; match to protein family HMM PF01476; elastin binding protein 1561813 3237648 SACOL1522 Staphylococcus aureus subsp. aureus COL elastin binding protein YP_186365.1 1560353 R 93062 CDS YP_186366.1 57650437 3237732 complement(1561966..1563345) 1 NC_002951.2 identified by similarity to EGAD:37724; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851; match to protein family HMM TIGR00614; ATP-dependent DNA helicase RecQ 1563345 recQ2 3237732 recQ2 Staphylococcus aureus subsp. aureus COL ATP-dependent DNA helicase RecQ YP_186366.1 1561966 R 93062 CDS YP_186367.1 57650438 3237558 complement(1563335..1564288) 1 NC_002951.2 identified by similarity to EGAD:37723; hypothetical protein 1564288 3237558 SACOL1524 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186367.1 1563335 R 93062 CDS YP_186368.1 57650439 3237609 1564396..1564644 1 NC_002951.2 identified by similarity to SP:P50727; ferredoxin 1564644 fer 3237609 fer Staphylococcus aureus subsp. aureus COL ferredoxin YP_186368.1 1564396 D 93062 CDS YP_186369.1 57650440 3237608 complement(1564750..1565295) 1 NC_002951.2 identified by similarity to EGAD:37721; hypothetical protein 1565295 3237608 SACOL1526 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186369.1 1564750 R 93062 CDS YP_186370.1 57650441 3237293 complement(1565892..1566806) 1 NC_002951.2 hypothetical protein 1566806 3237293 SACOL1528 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186370.1 1565892 R 93062 CDS YP_186371.1 57650442 3237603 complement(1566821..1567027) 1 NC_002951.2 hypothetical protein 1567027 3237603 SACOL1529 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186371.1 1566821 R 93062 CDS YP_186372.1 57650443 3237574 complement(1567020..1567898) 1 NC_002951.2 hypothetical protein 1567898 3237574 SACOL1530 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186372.1 1567020 R 93062 CDS YP_186373.1 57650444 3237841 complement(1568016..1568933) 1 NC_002951.2 hypothetical protein 1568933 3237841 SACOL1531 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186373.1 1568016 R 93062 CDS YP_186374.1 57650445 3237961 complement(1569024..1571186) 1 NC_002951.2 hypothetical protein 1571186 3237961 SACOL1532 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186374.1 1569024 R 93062 CDS YP_186375.1 57650446 3237403 complement(1571179..1572048) 1 NC_002951.2 hypothetical protein 1572048 3237403 SACOL1533 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186375.1 1571179 R 93062 CDS YP_186376.1 57650447 3237988 complement(1572353..1574104) 1 NC_002951.2 identified by similarity to GP:7839534; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase SrrB 1574104 srrB 3237988 srrB Staphylococcus aureus subsp. aureus COL sensor histidine kinase SrrB YP_186376.1 1572353 R 93062 CDS YP_186377.1 57650448 3237860 complement(1574085..1574810) 1 NC_002951.2 identified by similarity to GP:7839533; match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator SrrA 1574810 srrA 3237860 srrA Staphylococcus aureus subsp. aureus COL DNA-binding response regulator SrrA YP_186377.1 1574085 R 93062 CDS YP_186378.1 57650449 3237734 complement(1574943..1575680) 1 NC_002951.2 identified by similarity to EGAD:14622; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; ribosomal large subunit pseudouridine synthase B 1575680 rluB 3237734 rluB Staphylococcus aureus subsp. aureus COL ribosomal large subunit pseudouridine synthase B YP_186378.1 1574943 R 93062 CDS YP_186379.1 57650450 3237564 complement(1575673..1576215) 1 NC_002951.2 identified by similarity to EGAD:15088; match to protein family HMM PF04079; match to protein family HMM TIGR00281; segregation and condensation protein B 1576215 scpB 3237564 scpB Staphylococcus aureus subsp. aureus COL segregation and condensation protein B YP_186379.1 1575673 R 93062 CDS YP_186380.1 57650451 3237782 complement(1576208..1576939) 1 NC_002951.2 identified by similarity to EGAD:14314; match to protein family HMM PF02616; hypothetical protein 1576939 scpA 3237782 scpA Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186380.1 1576208 R 93062 CDS YP_186381.1 57650452 3237874 1577031..1577537 1 NC_002951.2 identified by similarity to EGAD:12647; match to protein family HMM PF03745; hypothetical protein 1577537 3237874 SACOL1539 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186381.1 1577031 D 93062 CDS YP_186382.1 57650453 3237654 complement(1577615..1578502) 1 NC_002951.2 identified by similarity to EGAD:24225; match to protein family HMM PF00589; match to protein family HMM PF02899; match to protein family HMM TIGR02225; tyrosine recombinase XerD 1578502 xerD 3237654 xerD Staphylococcus aureus subsp. aureus COL tyrosine recombinase XerD YP_186382.1 1577615 R 93062 CDS YP_186383.1 57650454 3237853 complement(1578551..1579000) 1 NC_002951.2 identified by similarity to EGAD:14407; match to protein family HMM PF01475; FUR family transcriptional regulator 1579000 3237853 SACOL1541 Staphylococcus aureus subsp. aureus COL FUR family transcriptional regulator YP_186383.1 1578551 R 93062 CDS YP_186384.1 57650455 3236300 complement(1579105..1579647) 1 NC_002951.2 identified by match to protein family HMM PF00293; MutT/nudix family protein 1579647 3236300 SACOL1542 Staphylococcus aureus subsp. aureus COL MutT/nudix family protein YP_186384.1 1579105 R 93062 CDS YP_186385.1 57650456 3237580 1579729..1580637 1 NC_002951.2 identified by match to protein family HMM PF00248; aldo/keto reductase oxidoreductase 1580637 3237580 SACOL1543 Staphylococcus aureus subsp. aureus COL aldo/keto reductase oxidoreductase YP_186385.1 1579729 D 93062 CDS YP_186386.1 57650457 3237682 complement(1580853..1581101) 1 NC_002951.2 hypothetical protein 1581101 3237682 SACOL1544 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186386.1 1580853 R 93062 CDS YP_186387.1 57650458 3237781 complement(1581117..1581872) 1 NC_002951.2 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase 1581872 3237781 SACOL1545 Staphylococcus aureus subsp. aureus COL short chain dehydrogenase/reductase oxidoreductase YP_186387.1 1581117 R 93062 CDS YP_186388.1 57650459 3237752 1582014..1582829 1 NC_002951.2 identified by similarity to EGAD:45894; match to protein family HMM PF01089; match to protein family HMM TIGR00112; pyrroline-5-carboxylate reductase 1582829 proC 3237752 proC Staphylococcus aureus subsp. aureus COL pyrroline-5-carboxylate reductase YP_186388.1 1582014 D 93062 CDS YP_186389.1 57650460 3237779 complement(1582934..1583854) 1 NC_002951.2 identified by match to protein family HMM PF00753; AtsA/ElaC family protein 1583854 3237779 SACOL1548 Staphylococcus aureus subsp. aureus COL AtsA/ElaC family protein YP_186389.1 1582934 R 93062 CDS YP_186390.1 57650461 3237569 1584167..1585651 1 NC_002951.2 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1585651 zwf 3237569 zwf Staphylococcus aureus subsp. aureus COL glucose-6-phosphate 1-dehydrogenase YP_186390.1 1584167 D 93062 CDS YP_186391.1 57650462 3237556 1585854..1586747 1 NC_002951.2 identified by match to protein family HMM PF00165; match to protein family HMM PF06445; AraC family transcriptional regulator 1586747 3237556 SACOL1550 Staphylococcus aureus subsp. aureus COL AraC family transcriptional regulator YP_186391.1 1585854 D 93062 CDS YP_186392.1 57650463 3237582 complement(1586830..1588479) 1 NC_002951.2 identified by similarity to EGAD:18543; match to protein family HMM PF00128; alpha-D-1,4-glucosidase 1588479 malA 3237582 malA Staphylococcus aureus subsp. aureus COL alpha-D-1,4-glucosidase YP_186392.1 1586830 R 93062 CDS YP_186393.1 57650464 3237327 complement(1588495..1589514) 1 NC_002951.2 identified by similarity to EGAD:23070; match to protein family HMM PF00356; match to protein family HMM PF00532; maltose operon transcriptional repressor 1589514 malR 3237327 malR Staphylococcus aureus subsp. aureus COL maltose operon transcriptional repressor YP_186393.1 1588495 R 93062 CDS YP_186394.1 57650465 3237917 complement(1589708..1590079) 1 NC_002951.2 identified by match to protein family HMM PF00903; glyoxalase 1590079 3237917 SACOL1553 Staphylococcus aureus subsp. aureus COL glyoxalase YP_186394.1 1589708 R 93062 CDS YP_186395.1 57650466 3237561 complement(1590298..1591704) 1 NC_002951.2 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 1591704 gnd 3237561 gnd Staphylococcus aureus subsp. aureus COL 6-phosphogluconate dehydrogenase YP_186395.1 1590298 R 93062 CDS YP_186396.1 57650467 3237560 complement(1591772..1592905) 1 NC_002951.2 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01883; M20/M25/M40 family peptidase 1592905 3237560 SACOL1555 Staphylococcus aureus subsp. aureus COL M20/M25/M40 family peptidase YP_186396.1 1591772 R 93062 CDS YP_186397.1 57650468 3237465 1593168..1593347 1 NC_002951.2 hypothetical protein 1593347 3237465 SACOL1556 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186397.1 1593168 D 93062 CDS YP_186398.1 57650469 3237572 complement(1593474..1594454) 1 NC_002951.2 identified by similarity to EGAD:45880; match to protein family HMM PF06081; hypothetical protein 1594454 3237572 SACOL1557 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186398.1 1593474 R 93062 CDS YP_186399.1 57650470 3237457 complement(1594468..1594905) 1 NC_002951.2 identified by similarity to EGAD:45876; match to protein family HMM PF06491; hypothetical protein 1594905 3237457 SACOL1558 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186399.1 1594468 R 93062 CDS YP_186400.1 57650471 3237583 complement(1594978..1595076) 1 NC_002951.2 hypothetical protein 1595076 3237583 SACOL1559 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186400.1 1594978 R 93062 CDS YP_186401.1 57650472 3237932 complement(1595256..1596530) 1 NC_002951.2 identified by similarity to EGAD:13011; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; 2-oxoisovalerate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase 1596530 3237932 SACOL1560 Staphylococcus aureus subsp. aureus COL 2-oxoisovalerate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase YP_186401.1 1595256 R 93062 CDS YP_186402.1 57650473 3237795 complement(1596543..1597526) 1 NC_002951.2 identified by match to protein family HMM PF02779; match to protein family HMM PF02780; 2-oxoisovalerate dehydrogenase, E1 component subunit beta 1597526 3237795 SACOL1561 Staphylococcus aureus subsp. aureus COL 2-oxoisovalerate dehydrogenase, E1 component subunit beta YP_186402.1 1596543 R 93062 CDS YP_186403.1 57650474 3237906 complement(1597526..1598518) 1 NC_002951.2 identified by match to protein family HMM PF00676; 2-oxoisovalerate dehydrogenase, E1 component subunit alpha 1598518 3237906 SACOL1562 Staphylococcus aureus subsp. aureus COL 2-oxoisovalerate dehydrogenase, E1 component subunit alpha YP_186403.1 1597526 R 93062 CDS YP_186404.1 57650475 3236287 complement(1598534..1599955) 1 NC_002951.2 identified by similarity to SP:P54533; match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM TIGR01350; dihydrolipoamide dehydrogenase 1599955 lpdA 3236287 lpdA Staphylococcus aureus subsp. aureus COL dihydrolipoamide dehydrogenase YP_186404.1 1598534 R 93062 CDS YP_186405.1 57650476 3237920 complement(1600106..1601785) 1 NC_002951.2 identified by similarity to EGAD:12400; match to protein family HMM TIGR00634; DNA repair protein RecN 1601785 recN 3237920 recN Staphylococcus aureus subsp. aureus COL DNA repair protein RecN YP_186405.1 1600106 R 93062 CDS YP_186406.1 57650477 3237573 complement(1601801..1602253) 1 NC_002951.2 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 1602253 argR 3237573 argR Staphylococcus aureus subsp. aureus COL arginine repressor YP_186406.1 1601801 R 93062 CDS YP_186407.1 57650478 3237242 complement(1602685..1603566) 1 NC_002951.2 identified by similarity to SP:Q08291; match to protein family HMM PF00348; geranyltranstransferase 1603566 ispA 3237242 ispA Staphylococcus aureus subsp. aureus COL geranyltranstransferase YP_186407.1 1602685 R 93062 CDS YP_186408.1 57650479 3237334 complement(1603544..1603774) 1 NC_002951.2 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1603774 xseB 3237334 xseB Staphylococcus aureus subsp. aureus COL exodeoxyribonuclease VII small subunit YP_186408.1 1603544 R 93062 CDS YP_186409.1 57650480 3237842 complement(1603767..1605104) 1 NC_002951.2 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1605104 xseA 3237842 xseA Staphylococcus aureus subsp. aureus COL exodeoxyribonuclease VII large subunit YP_186409.1 1603767 R 93062 CDS YP_186410.1 57650481 3237373 complement(1605121..1605510) 1 NC_002951.2 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 1605510 nusB 3237373 nusB Staphylococcus aureus subsp. aureus COL transcription antitermination protein NusB YP_186410.1 1605121 R 93062 CDS YP_186411.1 57650482 3237733 complement(1605570..1605932) 1 NC_002951.2 identified by similarity to EGAD:45861; match to protein family HMM PF03780; hypothetical protein 1605932 3237733 SACOL1570 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186411.1 1605570 R 93062 CDS YP_186412.1 57650483 3237941 complement(1605947..1607302) 1 NC_002951.2 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 1607302 accC 3237941 accC Staphylococcus aureus subsp. aureus COL acetyl-CoA carboxylase biotin carboxylase subunit YP_186412.1 1605947 R 93062 CDS YP_186413.1 57650484 3236296 complement(1607302..1607766) 1 NC_002951.2 identified by similarity to SP:P49786; match to protein family HMM PF00364; match to protein family HMM TIGR00531; acetyl-CoA carboxylase, biotin carboxyl carrier protein 1607766 accB 3236296 accB Staphylococcus aureus subsp. aureus COL acetyl-CoA carboxylase, biotin carboxyl carrier protein YP_186413.1 1607302 R 93062 CDS YP_186414.1 57650485 3237304 complement(1609250..1609591) 1 NC_002951.2 identified by similarity to EGAD:108527; hypothetical protein 1609591 3237304 SACOL1574 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186414.1 1609250 R 93062 CDS YP_186415.1 57650486 3237690 complement(1609647..1610237) 1 NC_002951.2 hypothetical protein 1610237 3237690 SACOL1575 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186415.1 1609647 R 93062 CDS YP_186416.1 57650487 3237681 complement(1610244..1611290) 1 NC_002951.2 identified by similarity to EGAD:23152; match to protein family HMM PF05257; traG protein 1611290 3237681 SACOL1576 Staphylococcus aureus subsp. aureus COL traG protein YP_186416.1 1610244 R 93062 CDS YP_186417.1 57650488 3237668 complement(1611280..1613127) 1 NC_002951.2 identified by similarity to EGAD:108524; hypothetical protein 1613127 3237668 SACOL1577 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186417.1 1611280 R 93062 CDS YP_186418.1 57650489 3237610 complement(1613132..1614490) 1 NC_002951.2 identified by match to protein family HMM PF01580; FtsK/SpoIIIE family protein 1614490 3237610 SACOL1578 Staphylococcus aureus subsp. aureus COL FtsK/SpoIIIE family protein YP_186418.1 1613132 R 93062 CDS YP_186419.1 57650490 3236299 complement(1614544..1617039) 1 NC_002951.2 identified by similarity to EGAD:108522; hypothetical protein 1617039 3236299 SACOL1579 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186419.1 1614544 R 93062 CDS YP_186420.1 57650491 3236084 complement(1617074..1617457) 1 NC_002951.2 hypothetical protein 1617457 3236084 SACOL1580 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186420.1 1617074 R 93062 CDS YP_186421.1 57650492 3237607 complement(1617469..1617729) 1 NC_002951.2 identified by similarity to EGAD:108519; hypothetical protein 1617729 3237607 SACOL1581 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186421.1 1617469 R 93062 CDS YP_186422.1 57650493 3237978 complement(1617734..1618789) 1 NC_002951.2 identified by similarity to GP:1881301; hypothetical protein 1618789 3237978 SACOL1582 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186422.1 1617734 R 93062 CDS YP_186423.1 57651919 3238227 complement(1618850..1619941) 1 NC_002951.2 identified by similarity to EGAD:108511; match to protein family HMM PF02486; replication initiation factor family protein 1619941 3238227 SACOL1583 Staphylococcus aureus subsp. aureus COL replication initiation factor family protein YP_186423.1 1618850 R 93062 CDS YP_186424.1 57651920 3238228 complement(1620116..1620418) 1 NC_002951.2 hypothetical protein 1620418 3238228 SACOL1584 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186424.1 1620116 R 93062 CDS YP_186425.1 57651921 3238534 complement(1620432..1620752) 1 NC_002951.2 identified by similarity to EGAD:108509; hypothetical protein 1620752 3238534 SACOL1585 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186425.1 1620432 R 93062 CDS YP_186426.1 57651922 3238535 complement(1620903..1621187) 1 NC_002951.2 hypothetical protein 1621187 3238535 SACOL1586 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186426.1 1620903 R 93062 CDS YP_186427.1 57651923 3238536 complement(1621582..1622139) 1 NC_002951.2 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1622139 efp 3238536 efp Staphylococcus aureus subsp. aureus COL elongation factor P YP_186427.1 1621582 R 93062 CDS YP_186428.1 57651924 3238537 complement(1622165..1623226) 1 NC_002951.2 identified by similarity to GP:3372642; match to protein family HMM PF00557; proline dipeptidase 1623226 3238537 SACOL1588 Staphylococcus aureus subsp. aureus COL proline dipeptidase YP_186428.1 1622165 R 93062 CDS YP_186429.1 57651925 3238538 1623331..1623912 1 NC_002951.2 identified by similarity to GP:6606214; hypothetical protein 1623912 3238538 SACOL1589 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186429.1 1623331 D 93062 CDS YP_186430.1 57651926 3238539 1623926..1624144 1 NC_002951.2 identified by similarity to GB:AAO04815.1; hypothetical protein 1624144 3238539 SACOL1590 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186430.1 1623926 D 93062 CDS YP_186431.1 57651927 3238023 complement(1624208..1625038) 1 NC_002951.2 identified by match to protein family HMM PF03099; lipoate-protein ligase A family protein 1625038 3238023 SACOL1591 Staphylococcus aureus subsp. aureus COL lipoate-protein ligase A family protein YP_186431.1 1624208 R 93062 CDS YP_186432.1 57651928 3238024 1625196..1625582 1 NC_002951.2 identified by match to protein family HMM PF00581; rhodanese-like domain-containing protein 1625582 3238024 SACOL1592 Staphylococcus aureus subsp. aureus COL rhodanese-like domain-containing protein YP_186432.1 1625196 D 93062 CDS YP_186433.1 57651929 3238025 complement(1625947..1627419) 1 NC_002951.2 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; glycine dehydrogenase subunit 2 1627419 3238025 SACOL1593 Staphylococcus aureus subsp. aureus COL glycine dehydrogenase subunit 2 YP_186433.1 1625947 R 93062 CDS YP_186434.1 57651930 3238026 complement(1627412..1628758) 1 NC_002951.2 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein; glycine dehydrogenase subunit 1 1628758 3238026 SACOL1594 Staphylococcus aureus subsp. aureus COL glycine dehydrogenase subunit 1 YP_186434.1 1627412 R 93062 CDS YP_186435.1 57651931 3238027 complement(1628778..1629869) 1 NC_002951.2 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 1629869 gcvT 3238027 gcvT Staphylococcus aureus subsp. aureus COL glycine cleavage system aminomethyltransferase T YP_186435.1 1628778 R 93062 CDS YP_186436.1 57651932 3238028 complement(1630028..1630552) 1 NC_002951.2 identified by similarity to EGAD:29699; match to protein family HMM PF01202; shikimate kinase 1630552 aroK 3238028 aroK Staphylococcus aureus subsp. aureus COL shikimate kinase YP_186436.1 1630028 R 93062 CDS YP_186437.1 57651933 3236386 complement(1630785..1631282) 1 NC_002951.2 hypothetical protein 1631282 3236386 SACOL1597 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186437.1 1630785 R 93062 CDS YP_186438.1 57651934 3236387 complement(1631486..1631932) 1 NC_002951.2 hypothetical protein 1631932 3236387 SACOL1598 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186438.1 1631486 R 93062 CDS YP_186439.1 57651935 3236388 complement(1631910..1632221) 1 NC_002951.2 identified by similarity to EGAD:18290; comG operon protein 3 precursor 1632221 comGC 3236388 comGC Staphylococcus aureus subsp. aureus COL comG operon protein 3 precursor YP_186439.1 1631910 R 93062 CDS YP_186440.1 57651936 3236389 complement(1632235..1633305) 1 NC_002951.2 identified by similarity to EGAD:21818; match to protein family HMM PF00482; competence protein ComGB 1633305 3236389 SACOL1600 Staphylococcus aureus subsp. aureus COL competence protein ComGB YP_186440.1 1632235 R 93062 CDS YP_186441.1 57651937 3236390 complement(1633277..1634251) 1 NC_002951.2 identified by similarity to EGAD:12231; match to protein family HMM PF00437; competence protein comGA 1634251 3236390 SACOL1601 Staphylococcus aureus subsp. aureus COL competence protein comGA YP_186441.1 1633277 R 93062 CDS YP_186442.1 57651938 3236391 complement(1634303..1634926) 1 NC_002951.2 identified by match to protein family HMM PF00753; metallo-beta-lactamase 1634926 3236391 SACOL1602 Staphylococcus aureus subsp. aureus COL metallo-beta-lactamase YP_186442.1 1634303 R 93062 CDS YP_186443.1 57651939 3236609 complement(1634923..1635252) 1 NC_002951.2 identified by similarity to EGAD:36859; match to protein family HMM PF01910; match to protein family HMM TIGR00106; hypothetical protein 1635252 3236609 SACOL1603 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186443.1 1634923 R 93062 CDS YP_186444.1 57651940 3236610 complement(1635252..1636238) 1 NC_002951.2 identified by match to protein family HMM PF00480; match to protein family HMM TIGR00744; glucokinase 1636238 glk 3236610 glk Staphylococcus aureus subsp. aureus COL glucokinase YP_186444.1 1635252 R 93062 CDS YP_186445.1 57651941 3236611 complement(1636235..1636438) 1 NC_002951.2 identified by similarity to EGAD:45836; match to protein family HMM PF06014; hypothetical protein 1636438 3236611 SACOL1605 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186445.1 1636235 R 93062 CDS YP_186446.1 57651942 3236612 complement(1636419..1637882) 1 NC_002951.2 identified by match to protein family HMM PF01694; rhomboid family protein 1637882 3236612 SACOL1606 Staphylococcus aureus subsp. aureus COL rhomboid family protein YP_186446.1 1636419 R 93062 CDS YP_186447.1 57651943 3236613 complement(1637894..1638433) 1 NC_002951.2 identified by match to protein family HMM PF01812; 5-formyltetrahydrofolate cyclo-ligase 1638433 3236613 SACOL1607 Staphylococcus aureus subsp. aureus COL 5-formyltetrahydrofolate cyclo-ligase YP_186447.1 1637894 R 93062 CDS YP_186448.1 57651944 3236614 complement(1638642..1638791) 1 NC_002951.2 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1638791 rpmG 3236614 rpmG Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L33 YP_186448.1 1638642 R 93062 CDS YP_186449.1 57651945 3236573 complement(1638904..1640979) 1 NC_002951.2 identified by similarity to OMNI:SA1609; match to protein family HMM PF00905; match to protein family HMM PF03717; penicillin-binding protein 3 1640979 pbp3 3236573 pbp3 Staphylococcus aureus subsp. aureus COL penicillin-binding protein 3 YP_186449.1 1638904 R 93062 CDS YP_186450.1 57651946 3236574 complement(1641100..1641699) 1 NC_002951.2 identified by similarity to SP:P54375; match to protein family HMM PF00081; match to protein family HMM PF02777; superoxide dismutase 1641699 sodA2 3236574 sodA2 Staphylococcus aureus subsp. aureus COL superoxide dismutase YP_186450.1 1641100 R 93062 CDS YP_186451.1 57651947 3236575 complement(1641975..1642385) 1 NC_002951.2 identified by match to protein family HMM PF01475; FUR family transcriptional regulator 1642385 3236575 SACOL1611 Staphylococcus aureus subsp. aureus COL FUR family transcriptional regulator YP_186451.1 1641975 R 93062 CDS YP_186452.1 57651948 3236576 complement(1642372..1643235) 1 NC_002951.2 identified by match to protein family HMM PF00950; ABC transporter permease 1643235 3236576 SACOL1612 Staphylococcus aureus subsp. aureus COL ABC transporter permease YP_186452.1 1642372 R 93062 CDS YP_186453.1 57651949 3236577 complement(1643277..1644062) 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1644062 3236577 SACOL1613 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_186453.1 1643277 R 93062 CDS YP_186454.1 57651950 3236578 complement(1644188..1645078) 1 NC_002951.2 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 1645078 nfo 3236578 nfo Staphylococcus aureus subsp. aureus COL endonuclease IV YP_186454.1 1644188 R 93062 CDS YP_186455.1 57651951 3236615 complement(1645088..1646434) 1 NC_002951.2 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; DEAD/DEAH box helicase 1646434 3236615 SACOL1615 Staphylococcus aureus subsp. aureus COL DEAD/DEAH box helicase YP_186455.1 1645088 R 93062 CDS YP_186456.1 57651952 3236616 complement(1646548..1647648) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH1383; match to protein family HMM PF01784; match to protein family HMM TIGR00486; hypothetical protein 1647648 3236616 SACOL1616 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186456.1 1646548 R 93062 CDS YP_186457.1 57651953 3236617 complement(1647651..1648328) 1 NC_002951.2 identified by similarity to OMNI:NTL01LL1087; match to protein family HMM PF04816; hypothetical protein 1648328 3236617 SACOL1617 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186457.1 1647651 R 93062 CDS YP_186458.1 57651954 3236618 complement(1648459..1649565) 1 NC_002951.2 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 1649565 rpoD 3236618 rpoD Staphylococcus aureus subsp. aureus COL RNA polymerase sigma factor RpoD YP_186458.1 1648459 R 93062 CDS YP_186459.1 57651955 3236619 complement(1649789..1651588) 1 NC_002951.2 identified by similarity to EGAD:32007; match to protein family HMM PF01751; match to protein family HMM PF01807; match to protein family HMM TIGR01391; DNA primase 1651588 dnaG 3236619 dnaG Staphylococcus aureus subsp. aureus COL DNA primase YP_186459.1 1649789 R 93062 CDS YP_186460.1 57651956 3238295 complement(1651649..1652467) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH1376; match to protein family HMM PF03618; hypothetical protein 1652467 3238295 SACOL1620 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186460.1 1651649 R 93062 CDS YP_186461.1 57651957 3238296 complement(1652478..1653017) 1 NC_002951.2 identified by match to protein family HMM PF00571; hypothetical protein 1653017 3238296 SACOL1621 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186461.1 1652478 R 93062 CDS YP_186462.1 57651958 3238297 1653436..1654827 1 NC_002951.2 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 1654827 glyS 3238297 glyS Staphylococcus aureus subsp. aureus COL glycyl-tRNA synthetase YP_186462.1 1653436 D 93062 CDS YP_186463.1 57651959 3238298 complement(1654977..1655729) 1 NC_002951.2 identified by match to protein family HMM PF02565; match to protein family HMM TIGR00613; RecO family DNA repair protein 1655729 3238298 SACOL1623 Staphylococcus aureus subsp. aureus COL RecO family DNA repair protein YP_186463.1 1654977 R 93062 CDS YP_186464.1 57651960 3238299 complement(1655751..1656650) 1 NC_002951.2 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1656650 era 3238299 era Staphylococcus aureus subsp. aureus COL GTP-binding protein Era YP_186464.1 1655751 R 93062 CDS YP_186465.1 57651961 3238300 complement(1656651..1657055) 1 NC_002951.2 identified by similarity to EGAD:8728; match to protein family HMM PF00383; match to protein family HMM TIGR01354; cytidine deaminase 1657055 cdd 3238300 cdd Staphylococcus aureus subsp. aureus COL cytidine deaminase YP_186465.1 1656651 R 93062 CDS YP_186466.1 57651962 3238273 complement(1657066..1657410) 1 NC_002951.2 identified by similarity to EGAD:11045; match to protein family HMM PF01219; diacylglycerol kinase 1657410 dgkA 3238273 dgkA Staphylococcus aureus subsp. aureus COL diacylglycerol kinase YP_186466.1 1657066 R 93062 CDS YP_186467.1 57651963 3238274 complement(1657413..1657880) 1 NC_002951.2 identified by similarity to EGAD:109021; match to protein family HMM PF02130; match to protein family HMM TIGR00043; hypothetical protein 1657880 3238274 SACOL1627 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186467.1 1657413 R 93062 CDS YP_186468.1 57651964 3238275 complement(1657881..1658801) 1 NC_002951.2 identified by match to protein family HMM PF00013; match to protein family HMM PF02562; PhoH family protein 1658801 3238275 SACOL1628 Staphylococcus aureus subsp. aureus COL PhoH family protein YP_186468.1 1657881 R 93062 CDS YP_186469.1 57651965 3238276 complement(1659132..1659830) 1 NC_002951.2 identified by similarity to GB:AAO04858.1; hypothetical protein 1659830 3238276 SACOL1629 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186469.1 1659132 R 93062 CDS YP_186470.1 57651966 3238277 complement(1659847..1660836) 1 NC_002951.2 identified by similarity to EGAD:45808; match to protein family HMM PF07251; hypothetical protein 1660836 3238277 SACOL1630 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186470.1 1659847 R 93062 CDS YP_186471.1 57651967 3238278 complement(1660854..1661561) 1 NC_002951.2 identified by similarity to EGAD:45807; hypothetical protein 1661561 3238278 SACOL1631 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186471.1 1660854 R 93062 CDS YP_186472.1 57651968 3238013 complement(1661781..1661957) 1 NC_002951.2 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 1661957 rpsU 3238013 rpsU Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S21 YP_186472.1 1661781 R 93062 CDS YP_186473.1 57651969 3238014 complement(1662250..1663596) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH1354; match to protein family HMM PF00919; match to protein family HMM PF01938; match to protein family HMM PF04055; match to protein family HMM TIGR00089; match to protein family HMM TIGR01579; hypothetical protein 1663596 3238014 SACOL1633 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186473.1 1662250 R 93062 CDS YP_186474.1 57651970 3238015 complement(1663603..1664355) 1 NC_002951.2 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1664355 3238015 SACOL1634 Staphylococcus aureus subsp. aureus COL 16S ribosomal RNA methyltransferase RsmE YP_186474.1 1663603 R 93062 CDS YP_186475.1 57651971 3238016 complement(1664357..1665295) 1 NC_002951.2 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 1665295 prmA 3238016 prmA Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L11 methyltransferase YP_186475.1 1664357 R 93062 CDS YP_186476.1 57651972 3238017 complement(1665299..1666438) 1 NC_002951.2 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 1666438 dnaJ 3238017 dnaJ Staphylococcus aureus subsp. aureus COL chaperone protein DnaJ YP_186476.1 1665299 R 93062 CDS YP_186477.1 57651973 3238018 complement(1666574..1668406) 1 NC_002951.2 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 1668406 dnaK 3238018 dnaK Staphylococcus aureus subsp. aureus COL molecular chaperone DnaK YP_186477.1 1666574 R 93062 CDS YP_186478.1 57651974 3238471 complement(1668475..1669101) 1 NC_002951.2 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 1669101 grpE 3238471 grpE Staphylococcus aureus subsp. aureus COL heat shock protein GrpE YP_186478.1 1668475 R 93062 CDS YP_186479.1 57651975 3238472 complement(1669133..1670110) 1 NC_002951.2 identified by similarity to EGAD:15810; match to protein family HMM PF01628; match to protein family HMM TIGR00331; heat-inducible transcription repressor HrcA 1670110 hrcA 3238472 hrcA Staphylococcus aureus subsp. aureus COL heat-inducible transcription repressor HrcA YP_186479.1 1669133 R 93062 CDS YP_186480.1 57651976 3238473 complement(1670210..1671367) 1 NC_002951.2 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1671367 3238473 SACOL1640 Staphylococcus aureus subsp. aureus COL coproporphyrinogen III oxidase YP_186480.1 1670210 R 93062 CDS YP_186481.1 57651977 3238474 complement(1671897..1673720) 1 NC_002951.2 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1673720 lepA 3238474 lepA Staphylococcus aureus subsp. aureus COL GTP-binding protein LepA YP_186481.1 1671897 R 93062 CDS YP_186482.1 57651978 3238475 1674066..1674317 1 NC_002951.2 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1674317 rpsT 3238475 rpsT Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S20 YP_186482.1 1674066 D 93062 CDS YP_186483.1 57651979 3238455 complement(1674362..1675336) 1 NC_002951.2 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 1675336 holA 3238455 holA Staphylococcus aureus subsp. aureus COL DNA polymerase III subunit delta YP_186483.1 1674362 R 93062 CDS YP_186484.1 57651980 3238456 complement(1675393..1677540) 1 NC_002951.2 identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361; competence protein ComEC/Rec2 1677540 3238456 SACOL1644 Staphylococcus aureus subsp. aureus COL competence protein ComEC/Rec2 YP_186484.1 1675393 R 93062 CDS YP_186485.1 57651981 3238457 complement(1677599..1678030) 1 NC_002951.2 identified by similarity to EGAD:23914; match to protein family HMM PF00383; comE operon protein 2 1678030 3238457 SACOL1645 Staphylococcus aureus subsp. aureus COL comE operon protein 2 YP_186485.1 1677599 R 93062 CDS YP_186486.1 57651982 3238458 complement(1678152..1678838) 1 NC_002951.2 identified by similarity to OMNI:NTL01SA1471; match to protein family HMM PF00633; match to protein family HMM TIGR00426; comE operon protein 1-like protein 1678838 comEA 3238458 comEA Staphylococcus aureus subsp. aureus COL comE operon protein 1-like protein YP_186486.1 1678152 R 93062 CDS YP_186487.1 57651983 3238459 complement(1678878..1679594) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH1333; hypothetical protein 1679594 3238459 SACOL1647 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186487.1 1678878 R 93062 CDS YP_186488.1 57651984 3238460 complement(1679597..1679950) 1 NC_002951.2 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090; hypothetical protein 1679950 3238460 SACOL1648 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186488.1 1679597 R 93062 CDS YP_186489.1 57651985 3236246 complement(1679951..1680535) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH1330; match to protein family HMM PF01966; match to protein family HMM TIGR00488; hypothetical protein 1680535 3236246 SACOL1649 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186489.1 1679951 R 93062 CDS YP_186490.1 57651986 3236247 complement(1680525..1681094) 1 NC_002951.2 identified by similarity to OMNI:NTL01SPL0234; match to protein family HMM PF01467; match to protein family HMM TIGR00125; match to protein family HMM TIGR00482; nicotinate (nicotinamide) nucleotide adenylyltransferase 1681094 nadD 3236247 nadD Staphylococcus aureus subsp. aureus COL nicotinate (nicotinamide) nucleotide adenylyltransferase YP_186490.1 1680525 R 93062 CDS YP_186491.1 57651987 3236248 complement(1681097..1681387) 1 NC_002951.2 identified by similarity to EGAD:45796; match to protein family HMM PF01985; match to protein family HMM TIGR00253; hypothetical protein 1681387 3236248 SACOL1651 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186491.1 1681097 R 93062 CDS YP_186492.1 57651988 3236249 complement(1681391..1682197) 1 NC_002951.2 identified by similarity to EGAD:45757; match to protein family HMM PF01488; match to protein family HMM TIGR00507; shikimate 5-dehydrogenase 1682197 aroE 3236249 aroE Staphylococcus aureus subsp. aureus COL shikimate 5-dehydrogenase YP_186492.1 1681391 R 93062 CDS YP_186493.1 57651989 3236250 complement(1682211..1683311) 1 NC_002951.2 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH 1683311 3236250 SACOL1653 Staphylococcus aureus subsp. aureus COL GTP-binding protein YqeH YP_186493.1 1682211 R 93062 CDS YP_186494.1 57651990 3236251 complement(1683312..1683839) 1 NC_002951.2 identified by similarity to OMNI:NTL01BS02561; match to protein family HMM TIGR01662; match to protein family HMM TIGR01668; HAD superfamily hydrolase 1683839 3236251 SACOL1654 Staphylococcus aureus subsp. aureus COL HAD superfamily hydrolase YP_186494.1 1683312 R 93062 CDS YP_186495.1 57651991 3236252 complement(1683859..1684545) 1 NC_002951.2 identified by similarity to EGAD:16140; match to protein family HMM PF01048; match to protein family HMM TIGR01704; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1684545 mtn 3236252 mtn Staphylococcus aureus subsp. aureus COL 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_186495.1 1683859 R 93062 CDS YP_186496.1 57651992 3236438 1684859..1685128 1 NC_002951.2 hypothetical protein 1685128 3236438 SACOL1656 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186496.1 1684859 D 93062 CDS YP_186497.1 57651993 3236439 complement(1685330..1686034) 1 NC_002951.2 identified by match to protein family HMM PF01123; match to protein family HMM PF02876; enterotoxin type A 1686034 3236439 SACOL1657 Staphylococcus aureus subsp. aureus COL enterotoxin type A YP_186497.1 1685330 R 93062 CDS YP_186498.1 57651994 3236440 complement(1686496..1687716) 1 NC_002951.2 hypothetical protein 1687716 3236440 SACOL1658 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186498.1 1686496 R 93062 CDS YP_186499.1 57651995 3236532 complement(1688005..1689234) 1 NC_002951.2 identified by similarity to GP:10174438; similarity to OMNI:NTL01BH1823; hypothetical protein 1689234 3236532 SACOL1659 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186499.1 1688005 R 93062 CDS YP_186500.1 57651996 3236533 complement(1689247..1689999) 1 NC_002951.2 identified by match to protein family HMM PF03746; LamB/YcsF family protein 1689999 3236533 SACOL1660 Staphylococcus aureus subsp. aureus COL LamB/YcsF family protein YP_186500.1 1689247 R 93062 CDS YP_186501.1 57651997 3236534 complement(1689999..1691360) 1 NC_002951.2 identified by similarity to SP:P49787; match to protein family HMM PF00289; match to protein family HMM PF02785; match to protein family HMM PF02786; acetyl-CoA carboxylase, biotin carboxylase 1691360 3236534 SACOL1661 Staphylococcus aureus subsp. aureus COL acetyl-CoA carboxylase, biotin carboxylase YP_186501.1 1689999 R 93062 CDS YP_186502.1 57651998 3236725 complement(1691374..1691823) 1 NC_002951.2 identified by similarity to SP:P49786; match to protein family HMM PF00364; acetyl-CoA carboxylase, biotin carboxyl carrier protein 1691823 3236725 SACOL1662 Staphylococcus aureus subsp. aureus COL acetyl-CoA carboxylase, biotin carboxyl carrier protein YP_186502.1 1691374 R 93062 CDS YP_186503.1 57651999 3236726 complement(1691825..1692835) 1 NC_002951.2 identified by match to protein family HMM PF02626; match to protein family HMM TIGR00724; hypothetical protein 1692835 3236726 SACOL1663 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186503.1 1691825 R 93062 CDS YP_186504.1 57652000 3236727 complement(1692825..1693559) 1 NC_002951.2 identified by similarity to OMNI:NTL01CJ01472; match to protein family HMM PF02682; match to protein family HMM TIGR00370; hypothetical protein 1693559 3236727 SACOL1664 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186504.1 1692825 R 93062 CDS YP_186505.1 57652001 3236728 complement(1693885..1694361) 1 NC_002951.2 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1694361 greA 3236728 greA Staphylococcus aureus subsp. aureus COL transcription elongation factor GreA YP_186505.1 1693885 R 93062 CDS YP_186506.1 57652002 3236729 complement(1694389..1695012) 1 NC_002951.2 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1695012 udk 3236729 udk Staphylococcus aureus subsp. aureus COL uridine kinase YP_186506.1 1694389 R 93062 CDS YP_186507.1 57650494 3237957 complement(1695012..1696280) 1 NC_002951.2 identified by match to protein family HMM PF01136; U32 family peptidase 1696280 3237957 SACOL1667 Staphylococcus aureus subsp. aureus COL U32 family peptidase YP_186507.1 1695012 R 93062 CDS YP_186508.1 57650495 3237600 complement(1696292..1697215) 1 NC_002951.2 identified by match to protein family HMM PF01136; U32 family peptidase 1697215 3237600 SACOL1668 Staphylococcus aureus subsp. aureus COL U32 family peptidase YP_186508.1 1696292 R 93062 CDS YP_186509.1 57650496 3237550 complement(1697218..1697856) 1 NC_002951.2 identified by match to protein family HMM PF01596; O-methyltransferase 1697856 3237550 SACOL1669 Staphylococcus aureus subsp. aureus COL O-methyltransferase YP_186509.1 1697218 R 93062 CDS YP_186510.1 57650497 3237578 complement(1698141..1698449) 1 NC_002951.2 identified by similarity to OMNI:EF1204; match to protein family HMM PF06949; hypothetical protein 1698449 3237578 SACOL1670 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186510.1 1698141 R 93062 CDS YP_186511.1 57650498 3236115 complement(1698464..1698892) 1 NC_002951.2 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 1698892 3236115 SACOL1671 Staphylococcus aureus subsp. aureus COL Holliday junction resolvase-like protein YP_186511.1 1698464 R 93062 CDS YP_186512.1 57650499 3237840 complement(1698896..1699156) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH1271; match to protein family HMM PF06135; hypothetical protein 1699156 3237840 SACOL1672 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186512.1 1698896 R 93062 CDS YP_186513.1 57650500 3237916 complement(1699219..1701849) 1 NC_002951.2 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1701849 alaS 3237916 alaS Staphylococcus aureus subsp. aureus COL alanyl-tRNA synthetase YP_186513.1 1699219 R 93062 CDS YP_186514.1 57650501 3237788 complement(1702192..1704669) 1 NC_002951.2 identified by match to protein family HMM TIGR01448; recombinase D 1704669 3237788 SACOL1674 Staphylococcus aureus subsp. aureus COL recombinase D YP_186514.1 1702192 R 93062 CDS YP_186515.1 57650502 3237637 complement(1704671..1705339) 1 NC_002951.2 identified by similarity to EGAD:107352; match to protein family HMM PF00515; TPR domain-containing protein 1705339 3237637 SACOL1675 Staphylococcus aureus subsp. aureus COL TPR domain-containing protein YP_186515.1 1704671 R 93062 CDS YP_186516.1 57650503 3237621 complement(1705801..1706919) 1 NC_002951.2 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1706919 mnmA 3237621 mnmA Staphylococcus aureus subsp. aureus COL tRNA-specific 2-thiouridylase MnmA YP_186516.1 1705801 R 93062 CDS YP_186517.1 57650504 3237374 complement(1706920..1708062) 1 NC_002951.2 identified by match to protein family HMM PF00266; class V aminotransferase 1708062 3237374 SACOL1677 Staphylococcus aureus subsp. aureus COL class V aminotransferase YP_186517.1 1706920 R 93062 CDS YP_186518.1 57650505 3237939 1708374..1709387 1 NC_002951.2 identified by match to protein family HMM PF00296; luciferase 1709387 3237939 SACOL1678 Staphylococcus aureus subsp. aureus COL luciferase YP_186518.1 1708374 D 93062 CDS YP_186519.1 57650506 3237813 complement(1709624..1709770) 1 NC_002951.2 identified by similarity to GB:AAO04906.1; hypothetical protein 1709770 3237813 SACOL1679 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186519.1 1709624 R 93062 CDS YP_186520.1 57650507 3238476 complement(1709810..1709992) 1 NC_002951.2 identified by similarity to GP:13622388; match to protein family HMM PF05532; hypothetical protein 1709992 3238476 SACOL1680 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186520.1 1709810 R 93062 CDS YP_186521.1 57650508 3238321 complement(1710092..1710514) 1 NC_002951.2 identified by match to protein family HMM PF02082; match to protein family HMM TIGR00738; Rrf2 family protein 1710514 3238321 SACOL1681 Staphylococcus aureus subsp. aureus COL Rrf2 family protein YP_186521.1 1710092 R 93062 CDS YP_186522.1 57650509 3238320 1710599..1711873 1 NC_002951.2 identified by match to protein family HMM PF00004; recombination factor protein RarA 1711873 3238320 SACOL1682 Staphylococcus aureus subsp. aureus COL recombination factor protein RarA YP_186522.1 1710599 D 93062 CDS YP_186523.1 57650510 3238611 complement(1712034..1712807) 1 NC_002951.2 identified by match to protein family HMM PF00899; hypothetical protein 1712807 3238611 SACOL1683 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186523.1 1712034 R 93062 CDS YP_186524.1 57650511 3238249 complement(1713268..1715034) 1 NC_002951.2 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1715034 aspS 3238249 aspS Staphylococcus aureus subsp. aureus COL aspartyl-tRNA synthetase YP_186524.1 1713268 R 93062 CDS YP_186525.1 57650512 3238238 complement(1715050..1716312) 1 NC_002951.2 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1716312 hisS 3238238 hisS Staphylococcus aureus subsp. aureus COL histidyl-tRNA synthetase YP_186525.1 1715050 R 93062 CDS YP_186526.1 57650513 3238432 complement(1716773..1717648) 1 NC_002951.2 identified by match to protein family HMM PF01520; N-acetylmuramoyl-L-alanine amidase 1717648 3238432 SACOL1687 Staphylococcus aureus subsp. aureus COL N-acetylmuramoyl-L-alanine amidase YP_186526.1 1716773 R 93062 CDS YP_186527.1 57650514 3238135 complement(1717645..1718097) 1 NC_002951.2 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1718097 3238135 SACOL1688 Staphylococcus aureus subsp. aureus COL D-tyrosyl-tRNA(Tyr) deacylase YP_186527.1 1717645 R 93062 CDS YP_186528.1 57650515 3238211 complement(1718109..1720298) 1 NC_002951.2 identified by similarity to EGAD:107375; match to protein family HMM PF01842; match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; GTP pyrophosphokinase 1720298 relA2 3238211 relA2 Staphylococcus aureus subsp. aureus COL GTP pyrophosphokinase YP_186528.1 1718109 R 93062 CDS YP_186529.1 57650516 3238414 complement(1720726..1721244) 1 NC_002951.2 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1721244 apt 3238414 apt Staphylococcus aureus subsp. aureus COL adenine phosphoribosyltransferase YP_186529.1 1720726 R 93062 CDS YP_186530.1 57650517 3238200 complement(1721266..1723539) 1 NC_002951.2 identified by similarity to EGAD:24228; match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644; single-stranded-DNA-specific exonuclease RecJ 1723539 recJ 3238200 recJ Staphylococcus aureus subsp. aureus COL single-stranded-DNA-specific exonuclease RecJ YP_186530.1 1721266 R 93062 CDS YP_186531.1 57650518 3238037 complement(1723742..1726021) 1 NC_002951.2 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; bifunctional preprotein translocase subunit SecD/SecF 1726021 3238037 SACOL1692 Staphylococcus aureus subsp. aureus COL bifunctional preprotein translocase subunit SecD/SecF YP_186531.1 1723742 R 93062 CDS YP_186532.1 57650519 3238482 complement(1726296..1726556) 1 NC_002951.2 identified by match to protein family HMM PF02699; match to protein family HMM TIGR00739; preprotein translocase, YajC subunit 1726556 yajC 3238482 yajC Staphylococcus aureus subsp. aureus COL preprotein translocase, YajC subunit YP_186532.1 1726296 R 93062 CDS YP_186533.1 57650520 3238043 complement(1726575..1727714) 1 NC_002951.2 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1727714 tgt 3238043 tgt Staphylococcus aureus subsp. aureus COL queuine tRNA-ribosyltransferase YP_186533.1 1726575 R 93062 CDS YP_186534.1 57650521 3238239 complement(1727737..1728762) 1 NC_002951.2 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1728762 queA 3238239 queA Staphylococcus aureus subsp. aureus COL S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_186534.1 1727737 R 93062 CDS YP_186535.1 57650522 3238142 complement(1728764..1729768) 1 NC_002951.2 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1729768 ruvB 3238142 ruvB Staphylococcus aureus subsp. aureus COL Holliday junction DNA helicase RuvB YP_186535.1 1728764 R 93062 CDS YP_186536.1 57650523 3238120 complement(1729800..1730402) 1 NC_002951.2 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1730402 ruvA 3238120 ruvA Staphylococcus aureus subsp. aureus COL Holliday junction DNA helicase RuvA YP_186536.1 1729800 R 93062 CDS YP_186537.1 57650524 3238485 complement(1730416..1730874) 1 NC_002951.2 identified by match to protein family HMM PF01842; hypothetical protein 1730874 3238485 SACOL1698 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186537.1 1730416 R 93062 CDS YP_186538.1 57650525 3238040 complement(1730884..1732176) 1 NC_002951.2 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1732176 obgE 3238040 obgE Staphylococcus aureus subsp. aureus COL GTPase ObgE YP_186538.1 1730884 R 93062 CDS YP_186539.1 57650526 3238006 complement(1732531..1732815) 1 NC_002951.2 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1732815 rpmA 3238006 rpmA Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L27 YP_186539.1 1732531 R 93062 CDS YP_186540.1 57650527 3238602 complement(1732827..1733147) 1 NC_002951.2 identified by similarity to EGAD:7018; match to protein family HMM PF04327; hypothetical protein 1733147 3238602 SACOL1701 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186540.1 1732827 R 93062 CDS YP_186541.1 57650528 3238052 complement(1733153..1733461) 1 NC_002951.2 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 1733461 rplU 3238052 rplU Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L21 YP_186541.1 1733153 R 93062 CDS YP_186542.1 57650529 3238463 complement(1733628..1734158) 1 NC_002951.2 identified by similarity to EGAD:24238; match to protein family HMM PF04093; rod shape-determining protein MreD 1734158 3238463 SACOL1703 Staphylococcus aureus subsp. aureus COL rod shape-determining protein MreD YP_186542.1 1733628 R 93062 CDS YP_186543.1 57650530 3238244 complement(1734158..1735000) 1 NC_002951.2 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 1735000 mreC 3238244 mreC Staphylococcus aureus subsp. aureus COL rod shape-determining protein MreC YP_186543.1 1734158 R 93062 CDS YP_186544.1 57650531 3238504 complement(1735393..1735866) 1 NC_002951.2 hypothetical protein 1735866 3238504 SACOL1705 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186544.1 1735393 R 93062 CDS YP_186545.1 57650532 3238572 complement(1736340..1736624) 1 NC_002951.2 hypothetical protein 1736624 3238572 SACOL1706 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186545.1 1736340 R 93062 CDS YP_186546.1 57650533 3238129 complement(1736692..1737378) 1 NC_002951.2 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1737378 radC 3238129 radC Staphylococcus aureus subsp. aureus COL DNA repair protein RadC YP_186546.1 1736692 R 93062 CDS YP_186547.1 57650534 3238643 complement(1737375..1738082) 1 NC_002951.2 identified by match to protein family HMM PF01478; match to protein family HMM PF06750; type III leader peptidase 1738082 3238643 SACOL1708 Staphylococcus aureus subsp. aureus COL type III leader peptidase YP_186547.1 1737375 R 93062 CDS YP_186548.1 57650535 3238701 complement(1738352..1739623) 1 NC_002951.2 identified by similarity to EGAD:12279; similarity to EGAD:42028; match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM TIGR01499; folylpolyglutamate synthase/dihydrofolate synthase 1739623 folC 3238701 folC Staphylococcus aureus subsp. aureus COL folylpolyglutamate synthase/dihydrofolate synthase YP_186548.1 1738352 R 93062 CDS YP_186549.1 57650536 3238312 complement(1739636..1742266) 1 NC_002951.2 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1742266 valS 3238312 valS Staphylococcus aureus subsp. aureus COL valyl-tRNA synthetase YP_186549.1 1739636 R 93062 CDS YP_186550.1 57650537 3238360 1742669..1743229 1 NC_002951.2 identified by similarity to EGAD:6433; match to protein family HMM PF03352; DNA-3-methyladenine glycosylase 1743229 3238360 SACOL1711 Staphylococcus aureus subsp. aureus COL DNA-3-methyladenine glycosylase YP_186550.1 1742669 D 93062 CDS YP_186551.1 57650538 3238556 complement(1743452..1744525) 1 NC_002951.2 identified by match to protein family HMM PF05145; abrB protein 1744525 3238556 SACOL1712 Staphylococcus aureus subsp. aureus COL abrB protein YP_186551.1 1743452 R 93062 CDS YP_186552.1 57650539 3238620 complement(1744721..1746007) 1 NC_002951.2 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 1746007 hemL1 3238620 hemL1 Staphylococcus aureus subsp. aureus COL glutamate-1-semialdehyde aminotransferase YP_186552.1 1744721 R 93062 CDS YP_186553.1 57650540 3238571 complement(1746055..1747029) 1 NC_002951.2 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 1747029 hemB 3238571 hemB Staphylococcus aureus subsp. aureus COL delta-aminolevulinic acid dehydratase YP_186553.1 1746055 R 93062 CDS YP_186554.1 57650541 3238340 complement(1747032..1747700) 1 NC_002951.2 identified by match to protein family HMM PF02602; uroporphyrinogen III synthase 1747700 hemD 3238340 hemD Staphylococcus aureus subsp. aureus COL uroporphyrinogen III synthase YP_186554.1 1747032 R 93062 CDS YP_186555.1 57650542 3238223 complement(1747722..1748648) 1 NC_002951.2 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 1748648 hemC 3238223 hemC Staphylococcus aureus subsp. aureus COL porphobilinogen deaminase YP_186555.1 1747722 R 93062 CDS YP_186556.1 57650543 3238353 complement(1748690..1749505) 1 NC_002951.2 identified by similarity to EGAD:15411; match to protein family HMM PF01578; hemX protein 1749505 3238353 SACOL1718 Staphylococcus aureus subsp. aureus COL hemX protein YP_186556.1 1748690 R 93062 CDS YP_186557.1 57650544 3236739 complement(1749527..1750873) 1 NC_002951.2 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1750873 hemA 3236739 hemA Staphylococcus aureus subsp. aureus COL glutamyl-tRNA reductase YP_186557.1 1749527 R 93062 CDS YP_186558.1 57650545 3238352 complement(1751090..1751680) 1 NC_002951.2 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1751680 engB 3238352 engB Staphylococcus aureus subsp. aureus COL ribosome biogenesis GTP-binding protein YsxC YP_186558.1 1751090 R 93062 CDS YP_186559.1 57650546 3238124 complement(1751834..1753096) 1 NC_002951.2 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1753096 clpX 3238124 clpX Staphylococcus aureus subsp. aureus COL ATP-dependent protease ATP-binding subunit ClpX YP_186559.1 1751834 R 93062 CDS YP_186560.1 57650547 3238349 complement(1753247..1754548) 1 NC_002951.2 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1754548 tig 3238349 tig Staphylococcus aureus subsp. aureus COL trigger factor YP_186560.1 1753247 R 93062 CDS YP_186561.1 57650548 3238351 complement(1754711..1755640) 1 NC_002951.2 identified by similarity to GB:AAO04950.1; hypothetical protein 1755640 3238351 SACOL1723 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186561.1 1754711 R 93062 CDS YP_186562.1 57650549 3238264 complement(1755659..1756267) 1 NC_002951.2 identified by match to protein family HMM PF00293; MutT/nudix family protein 1756267 3238264 SACOL1724 Staphylococcus aureus subsp. aureus COL MutT/nudix family protein YP_186562.1 1755659 R 93062 CDS YP_186563.1 57650550 3236569 complement(1756409..1756765) 1 NC_002951.2 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1756765 rplT 3236569 rplT Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L20 YP_186563.1 1756409 R 93062 CDS YP_186564.1 57650551 3236392 complement(1756812..1757012) 1 NC_002951.2 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001; 50S ribosomal protein L35 1757012 rpmI 3236392 rpmI Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L35 YP_186564.1 1756812 R 93062 CDS YP_186565.1 57650552 3237740 complement(1757041..1757568) 1 NC_002951.2 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1757568 infC 3237740 infC Staphylococcus aureus subsp. aureus COL translation initiation factor IF-3 YP_186565.1 1757041 R 93062 CDS YP_186566.1 57650553 3236213 complement(1757797..1759290) 1 NC_002951.2 identified by match to protein family HMM PF00324; amino acid permease 1759290 3236213 SACOL1728 Staphylococcus aureus subsp. aureus COL amino acid permease YP_186566.1 1757797 R 93062 CDS YP_186567.1 57650554 3236393 complement(1759716..1761653) 1 NC_002951.2 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1761653 thrS 3236393 thrS Staphylococcus aureus subsp. aureus COL threonyl-tRNA synthetase YP_186567.1 1759716 R 93062 CDS YP_186568.1 57650555 3238339 complement(1762066..1762986) 1 NC_002951.2 Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 1762986 dnaI 3238339 dnaI Staphylococcus aureus subsp. aureus COL primosomal protein DnaI YP_186568.1 1762066 R 93062 CDS YP_186569.1 57650556 3238557 complement(1762986..1764386) 1 NC_002951.2 identified by similarity to EGAD:12808; match to protein family HMM PF07261; replication initiation and membrane attachment protein 1764386 3238557 SACOL1732 Staphylococcus aureus subsp. aureus COL replication initiation and membrane attachment protein YP_186569.1 1762986 R 93062 CDS YP_186570.1 57650557 3238711 complement(1764387..1764857) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH3149; match to protein family HMM PF03477; match to protein family HMM TIGR00244; transcriptional regulator NrdR 1764857 nrdR 3238711 nrdR Staphylococcus aureus subsp. aureus COL transcriptional regulator NrdR YP_186570.1 1764387 R 93062 CDS YP_186571.1 57650558 3238151 complement(1765067..1766092) 1 NC_002951.2 identified by similarity to EGAD:107759; match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534; glyceraldehyde 3-phosphate dehydrogenase 2 1766092 gapA2 3238151 gapA2 Staphylococcus aureus subsp. aureus COL glyceraldehyde 3-phosphate dehydrogenase 2 YP_186571.1 1765067 R 93062 CDS YP_186572.1 57650559 3238585 complement(1766262..1766885) 1 NC_002951.2 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 1766885 coaE 3238585 coaE Staphylococcus aureus subsp. aureus COL dephospho-CoA kinase YP_186572.1 1766262 R 93062 CDS YP_186573.1 57650560 3238185 complement(1766901..1767773) 1 NC_002951.2 In the Gram-positive bacteria, the preferred gene symbol is fpg. In other prokaryotes, the gene symbol is mutM.identified by similarity to EGAD:8852; match to protein family HMM PF01149; match to protein family HMM PF06831; match to protein family HMM TIGR00577; formamidopyrimidine-DNA glycosylase 1767773 fpg 3238185 fpg Staphylococcus aureus subsp. aureus COL formamidopyrimidine-DNA glycosylase YP_186573.1 1766901 R 93062 CDS YP_186574.1 57650561 3238703 complement(1767789..1770419) 1 NC_002951.2 identified by similarity to EGAD:108026; match to protein family HMM PF00476; match to protein family HMM PF01367; match to protein family HMM PF01612; match to protein family HMM PF02739; match to protein family HMM TIGR00593; DNA polymerase I 1770419 polA 3238703 polA Staphylococcus aureus subsp. aureus COL DNA polymerase I YP_186574.1 1767789 R 93062 CDS YP_186575.1 57650562 3236400 complement(1770713..1772200) 1 NC_002951.2 hypothetical protein 1772200 3236400 SACOL1738 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186575.1 1770713 R 93062 CDS YP_186576.1 57650563 3236401 complement(1772699..1774363) 1 NC_002951.2 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensory box histidine kinase PhoR 1774363 3236401 SACOL1739 Staphylococcus aureus subsp. aureus COL sensory box histidine kinase PhoR YP_186576.1 1772699 R 93062 CDS YP_186577.1 57650564 3237708 complement(1774360..1775064) 1 NC_002951.2 identified by similarity to EGAD:18490; match to protein family HMM PF00072; match to protein family HMM PF00486; alkaline phosphatase synthesis transcriptional regulatory protein 1775064 phoP 3237708 phoP Staphylococcus aureus subsp. aureus COL alkaline phosphatase synthesis transcriptional regulatory protein YP_186577.1 1774360 R 93062 CDS YP_186578.1 57650565 3236289 complement(1775454..1776722) 1 NC_002951.2 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1776722 icd 3236289 icd Staphylococcus aureus subsp. aureus COL isocitrate dehydrogenase YP_186578.1 1775454 R 93062 CDS YP_186579.1 57650566 3238105 complement(1776771..1777892) 1 NC_002951.2 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; citrate synthase 1777892 gltA 3238105 gltA Staphylococcus aureus subsp. aureus COL citrate synthase YP_186579.1 1776771 R 93062 CDS YP_186580.1 57650567 3238324 1778240..1779601 1 NC_002951.2 identified by match to protein family HMM PF00324; amino acid permease 1779601 3238324 SACOL1743 Staphylococcus aureus subsp. aureus COL amino acid permease YP_186580.1 1778240 D 93062 CDS YP_186581.1 57650568 3238347 complement(1781926..1783683) 1 NC_002951.2 identified by similarity to EGAD:108035; match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; pyruvate kinase 1783683 pyk 3238347 pyk Staphylococcus aureus subsp. aureus COL pyruvate kinase YP_186581.1 1781926 R 93062 CDS YP_186582.1 57650569 3238326 complement(1783705..1784673) 1 NC_002951.2 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1784673 pfkA 3238326 pfkA Staphylococcus aureus subsp. aureus COL 6-phosphofructokinase YP_186582.1 1783705 R 93062 CDS YP_186583.1 57650570 3238265 complement(1784942..1785886) 1 NC_002951.2 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1785886 accA 3238265 accA Staphylococcus aureus subsp. aureus COL acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_186583.1 1784942 R 93062 CDS YP_186584.1 57650571 3238232 complement(1785886..1786743) 1 NC_002951.2 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 1786743 accD 3238232 accD Staphylococcus aureus subsp. aureus COL acetyl-CoA carboxylase subunit beta YP_186584.1 1785886 R 93062 CDS YP_186585.1 57650572 3238131 complement(1786938..1788167) 1 NC_002951.2 identified by match to protein family HMM PF00390; match to protein family HMM PF03949; NADP-dependent malic enzyme 1788167 3238131 SACOL1749 Staphylococcus aureus subsp. aureus COL NADP-dependent malic enzyme YP_186585.1 1786938 R 93062 CDS YP_186586.1 57650573 3238132 complement(1788617..1791814) 1 NC_002951.2 identified by similarity to EGAD:108043; match to protein family HMM PF01336; match to protein family HMM PF02231; match to protein family HMM TIGR00594; DNA polymerase III subunit alpha 1791814 dnaE 3238132 dnaE Staphylococcus aureus subsp. aureus COL DNA polymerase III subunit alpha YP_186586.1 1788617 R 93062 CDS YP_186587.1 57650574 3238462 complement(1791835..1792776) 1 NC_002951.2 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; hypothetical protein 1792776 3238462 SACOL1751 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186587.1 1791835 R 93062 CDS YP_186588.1 57652003 3236730 complement(1793037..1794335) 1 NC_002951.2 identified by match to protein family HMM PF00571; match to protein family HMM PF03061; match to protein family HMM PF07085; hypothetical protein 1794335 3236730 SACOL1752 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186588.1 1793037 R 93062 CDS YP_186589.1 57652004 3235990 1794540..1794953 1 NC_002951.2 identified by match to protein family HMM PF00582; universal stress protein 1794953 3235990 SACOL1753 Staphylococcus aureus subsp. aureus COL universal stress protein YP_186589.1 1794540 D 93062 CDS YP_186590.1 57652005 3235992 1796121..1797176 1 NC_002951.2 identified by similarity to EGAD:30261; match to protein family HMM PF00557; proline dipeptidase 1797176 pepQ 3235992 pepQ Staphylococcus aureus subsp. aureus COL proline dipeptidase YP_186590.1 1796121 D 93062 CDS YP_186591.1 57652006 3235993 complement(1797270..1797368) 1 NC_002951.2 hypothetical protein 1797368 3235993 SACOL1757 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186591.1 1797270 R 93062 CDS YP_186592.1 57652007 3235994 complement(1797492..1798610) 1 NC_002951.2 identified by similarity to EGAD:15508; match to protein family HMM PF01262; match to protein family HMM PF05222; match to protein family HMM TIGR00518; alanine dehydrogenase 1798610 ald2 3235994 ald2 Staphylococcus aureus subsp. aureus COL alanine dehydrogenase YP_186592.1 1797492 R 93062 CDS YP_186593.1 57652008 3235995 1798751..1799251 1 NC_002951.2 identified by match to protein family HMM PF00582; universal stress protein 1799251 3235995 SACOL1759 Staphylococcus aureus subsp. aureus COL universal stress protein YP_186593.1 1798751 D 93062 CDS YP_186594.1 57652009 3236755 complement(1799497..1800699) 1 NC_002951.2 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1800699 ackA 3236755 ackA Staphylococcus aureus subsp. aureus COL acetate kinase YP_186594.1 1799497 R 93062 CDS YP_186595.1 57652010 3236756 complement(1800787..1801734) 1 NC_002951.2 identified by similarity to EGAD:11836; hypothetical protein 1801734 3236756 SACOL1761 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186595.1 1800787 R 93062 CDS YP_186596.1 57652011 3236757 complement(1801857..1802351) 1 NC_002951.2 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1802351 tpx 3236757 tpx Staphylococcus aureus subsp. aureus COL thiol peroxidase YP_186596.1 1801857 R 93062 CDS YP_186597.1 57652012 3236758 complement(1802449..1803219) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH2125; match to protein family HMM PF01925; hypothetical protein 1803219 3236758 SACOL1763 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186597.1 1802449 R 93062 CDS YP_186598.1 57652013 3236759 complement(1803263..1804486) 1 NC_002951.2 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 1804486 thiI 3236759 thiI Staphylococcus aureus subsp. aureus COL thiamine biosynthesis protein ThiI YP_186598.1 1803263 R 93062 CDS YP_186599.1 57652014 3236760 complement(1804486..1805625) 1 NC_002951.2 identified by match to protein family HMM PF00266; class V aminotransferase 1805625 3236760 SACOL1765 Staphylococcus aureus subsp. aureus COL class V aminotransferase YP_186599.1 1804486 R 93062 CDS YP_186600.1 57652015 3236377 1805783..1805923 1 NC_002951.2 hypothetical protein 1805923 3236377 SACOL1766 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186600.1 1805783 D 93062 CDS YP_186601.1 57652016 3236378 complement(1805997..1807691) 1 NC_002951.2 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 1807691 3236378 SACOL1767 Staphylococcus aureus subsp. aureus COL septation ring formation regulator EzrA YP_186601.1 1805997 R 93062 CDS YP_186602.1 57652017 3236379 1807828..1808292 1 NC_002951.2 identified by match to protein family HMM PF01590; GAF domain-containing protein 1808292 3236379 SACOL1768 Staphylococcus aureus subsp. aureus COL GAF domain-containing protein YP_186602.1 1807828 D 93062 CDS YP_186603.1 57652018 3236380 1808536..1809138 1 NC_002951.2 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1809138 rpsD 3236380 rpsD Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S4 YP_186603.1 1808536 D 93062 CDS YP_186604.1 57652019 3236381 complement(1809354..1810097) 1 NC_002951.2 identified by similarity to EGAD:9350; match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase 1810097 3236381 SACOL1770 Staphylococcus aureus subsp. aureus COL glycerophosphoryl diester phosphodiesterase YP_186604.1 1809354 R 93062 CDS YP_186605.1 57652020 3236382 1810177..1810623 1 NC_002951.2 identified by match to protein family HMM PF02566; OsmC/Ohr family protein 1810623 3236382 SACOL1771 Staphylococcus aureus subsp. aureus COL OsmC/Ohr family protein YP_186605.1 1810177 D 93062 CDS YP_186606.1 57652021 3236383 1810737..1811897 1 NC_002951.2 identified by match to protein family HMM PF00266; class V aminotransferase 1811897 3236383 SACOL1772 Staphylococcus aureus subsp. aureus COL class V aminotransferase YP_186606.1 1810737 D 93062 CDS YP_186607.1 57652022 3236384 1811884..1813488 1 NC_002951.2 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1813488 serA 3236384 serA Staphylococcus aureus subsp. aureus COL D-3-phosphoglycerate dehydrogenase YP_186607.1 1811884 D 93062 CDS YP_186608.1 57652023 3236588 complement(1813638..1814768) 1 NC_002951.2 HAD superfamily hydrolase 1814768 3236588 SACOL1774 Staphylococcus aureus subsp. aureus COL HAD superfamily hydrolase YP_186608.1 1813638 R 93062 CDS YP_186609.1 57652024 3236589 complement(1814875..1816341) 1 NC_002951.2 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR01998; PTS system, IIBC components 1816341 3236589 SACOL1775 Staphylococcus aureus subsp. aureus COL PTS system, IIBC components YP_186609.1 1814875 R 93062 CDS YP_186610.1 57652025 3236590 complement(1816469..1817086) 1 NC_002951.2 identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530; 1-acyl-sn-glycerol-3-phosphate acyltransferase 1817086 3236590 SACOL1776 Staphylococcus aureus subsp. aureus COL 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_186610.1 1816469 R 93062 CDS YP_186611.1 57652026 3236591 1817258..1818532 1 NC_002951.2 identified by similarity to OMNI:NTL01LL2179; match to protein family HMM PF00089; match to protein family HMM PF00595; serine protease HtrA 1818532 3236591 SACOL1777 Staphylococcus aureus subsp. aureus COL serine protease HtrA YP_186611.1 1817258 D 93062 CDS YP_186612.1 57652027 3236592 complement(1818626..1819888) 1 NC_002951.2 identified by similarity to EGAD:22377; match to protein family HMM PF00579; match to protein family HMM PF01479; match to protein family HMM TIGR00234; tyrosyl-tRNA synthetase 1819888 tyrS 3236592 tyrS Staphylococcus aureus subsp. aureus COL tyrosyl-tRNA synthetase YP_186612.1 1818626 R 93062 CDS YP_186613.1 57652028 3236593 1820270..1821175 1 NC_002951.2 identified by match to protein family HMM PF00912; transglycosylase domain-containing protein 1821175 3236593 SACOL1779 Staphylococcus aureus subsp. aureus COL transglycosylase domain-containing protein YP_186613.1 1820270 D 93062 CDS YP_186614.1 57652029 3236594 complement(1821378..1824065) 1 NC_002951.2 identified by match to protein family HMM PF04650; match to protein family HMM PF05031; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; cell wall surface anchor family protein 1824065 3236594 SACOL1781 Staphylococcus aureus subsp. aureus COL cell wall surface anchor family protein YP_186614.1 1821378 R 93062 CDS YP_186615.2 228943815 3236749 complement(1824399..1826066) 1 NC_002951.2 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 1826066 fhs 3236749 fhs Staphylococcus aureus subsp. aureus COL formate--tetrahydrofolate ligase YP_186615.2 1824399 R 93062 CDS YP_186616.1 57652031 3236750 complement(1826506..1828212) 1 NC_002951.2 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 1828212 acs 3236750 acs Staphylococcus aureus subsp. aureus COL acetyl-CoA synthetase YP_186616.1 1826506 R 93062 CDS YP_186617.1 57652032 3236751 1828381..1829013 1 NC_002951.2 identified by similarity to EGAD:23882; acetoin utilization protein AcuA 1829013 acuA 3236751 acuA Staphylococcus aureus subsp. aureus COL acetoin utilization protein AcuA YP_186617.1 1828381 D 93062 CDS YP_186618.1 57652033 3236752 1829038..1830207 1 NC_002951.2 identified by similarity to EGAD:19784; match to protein family HMM PF00850; acetoin utilization protein AcuC 1830207 acuC 3236752 acuC Staphylococcus aureus subsp. aureus COL acetoin utilization protein AcuC YP_186618.1 1829038 D 93062 CDS YP_186619.1 57652034 3236753 complement(1830305..1831294) 1 NC_002951.2 identified by similarity to EGAD:41199; match to protein family HMM PF00356; match to protein family HMM PF00532; match to protein family HMM TIGR01481; catabolite control protein A 1831294 ccpA 3236753 ccpA Staphylococcus aureus subsp. aureus COL catabolite control protein A YP_186619.1 1830305 R 93062 CDS YP_186620.1 57652035 3236754 complement(1831834..1832925) 1 NC_002951.2 catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate; bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase 1832925 3236754 SACOL1787 Staphylococcus aureus subsp. aureus COL bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase YP_186620.1 1831834 R 93062 CDS YP_186621.1 57652036 3236013 complement(1833625..1835142) 1 NC_002951.2 hypothetical protein 1835142 3236013 SACOL1788 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186621.1 1833625 R 93062 CDS YP_186622.1 57652037 3236014 complement(1835216..1835707) 1 NC_002951.2 identified by similarity to EGAD:30617; match to protein family HMM PF06103; hypothetical protein 1835707 3236014 SACOL1789 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186622.1 1835216 R 93062 CDS YP_186623.1 57652038 3236015 complement(1835781..1837094) 1 NC_002951.2 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1837094 murC 3236015 murC Staphylococcus aureus subsp. aureus COL UDP-N-acetylmuramate--L-alanine ligase YP_186623.1 1835781 R 93062 CDS YP_186624.1 57652039 3236016 complement(1837118..1840942) 1 NC_002951.2 identified by match to protein family HMM PF01580; FtsK/SpoIIIE family protein 1840942 3236016 SACOL1791 Staphylococcus aureus subsp. aureus COL FtsK/SpoIIIE family protein YP_186624.1 1837118 R 93062 CDS YP_186625.1 57652040 3236017 complement(1840963..1841559) 1 NC_002951.2 identified by match to protein family HMM PF01588; hypothetical protein 1841559 3236017 SACOL1792 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186625.1 1840963 R 93062 CDS YP_186626.1 57652041 3236018 complement(1841588..1842445) 1 NC_002951.2 identified by similarity to OMNI:NTL01BS02977; match to protein family HMM PF07285; hypothetical protein 1842445 3236018 SACOL1793 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186626.1 1841588 R 93062 CDS YP_186627.1 57652042 3236019 complement(1842545..1842856) 1 NC_002951.2 identified by match to protein family HMM PF00085; thioredoxin 1842856 3236019 SACOL1794 Staphylococcus aureus subsp. aureus COL thioredoxin YP_186627.1 1842545 R 93062 CDS YP_186628.1 57652043 3236049 complement(1842921..1843997) 1 NC_002951.2 identified by similarity to EGAD:40297; match to protein family HMM PF05343; glutamyl aminopeptidase 1843997 pepA1 3236049 pepA1 Staphylococcus aureus subsp. aureus COL glutamyl aminopeptidase YP_186628.1 1842921 R 93062 CDS YP_186629.1 57652044 3236050 1844084..1844395 1 NC_002951.2 identified by similarity to OMNI:EF3039; match to protein family HMM PF03413; hypothetical protein 1844395 3236050 SACOL1796 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186629.1 1844084 D 93062 CDS YP_186630.1 57652045 3236051 complement(1844520..1845296) 1 NC_002951.2 identified by match to protein family HMM PF00753; metallo-beta-lactamase 1845296 3236051 SACOL1797 Staphylococcus aureus subsp. aureus COL metallo-beta-lactamase YP_186630.1 1844520 R 93062 CDS YP_186631.1 57652046 3236052 complement(1845832..1846476) 1 NC_002951.2 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 1846476 trmB 3236052 trmB Staphylococcus aureus subsp. aureus COL tRNA (guanine-N(7)-)-methyltransferase YP_186631.1 1845832 R 93062 CDS YP_186632.1 57652047 3236053 complement(1846491..1847282) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH3266; match to protein family HMM PF01636; hypothetical protein 1847282 3236053 SACOL1799 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186632.1 1846491 R 93062 CDS YP_186633.1 57652048 3236054 complement(1847832..1848680) 1 NC_002951.2 identified by similarity to EGAD:38031; match to protein family HMM PF01063; match to protein family HMM TIGR01121; D-alanine aminotransferase 1848680 dat 3236054 dat Staphylococcus aureus subsp. aureus COL D-alanine aminotransferase YP_186633.1 1847832 R 93062 CDS YP_186634.1 57652049 3236055 complement(1848684..1850093) 1 NC_002951.2 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 1850093 3236055 SACOL1801 Staphylococcus aureus subsp. aureus COL dipeptidase PepV YP_186634.1 1848684 R 93062 CDS YP_186635.1 57652050 3236027 complement(1851013..1851435) 1 NC_002951.2 identified by similarity to GB:AAO05024.1; hypothetical protein 1851435 3236027 SACOL1802 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186635.1 1851013 R 93062 CDS YP_186636.1 57652051 3236028 complement(1851452..1852147) 1 NC_002951.2 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00093; pseudouridine synthase 1 protein 1852147 3236028 SACOL1803 Staphylococcus aureus subsp. aureus COL pseudouridine synthase 1 protein YP_186636.1 1851452 R 93062 CDS YP_186637.1 57652052 3236029 complement(1852144..1853805) 1 NC_002951.2 identified by match to protein family HMM PF01943; polysaccharide biosynthesis protein 1853805 3236029 SACOL1804 Staphylococcus aureus subsp. aureus COL polysaccharide biosynthesis protein YP_186637.1 1852144 R 93062 CDS YP_186638.1 57652053 3236030 1854212..1855480 1 NC_002951.2 identified by similarity to OMNI:NTL01BH3282; match to protein family HMM PF03486; match to protein family HMM TIGR00275; hypothetical protein 1855480 3236030 SACOL1805 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186638.1 1854212 D 93062 CDS YP_186639.1 57652054 3236031 complement(1855597..1862157) 1 NC_002951.2 identified by match to protein family HMM PF04650; match to protein family HMM PF07564; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; cell wall surface anchor family protein 1862157 3236031 SACOL1806 Staphylococcus aureus subsp. aureus COL cell wall surface anchor family protein YP_186639.1 1855597 R 93062 CDS YP_186640.1 57652055 3236032 complement(1862483..1862794) 1 NC_002951.2 identified by match to protein family HMM PF00581; rhodanese-like domain-containing protein 1862794 3236032 SACOL1807 Staphylococcus aureus subsp. aureus COL rhodanese-like domain-containing protein YP_186640.1 1862483 R 93062 CDS YP_186641.1 57652056 3236033 complement(1862816..1865233) 1 NC_002951.2 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1865233 leuS 3236033 leuS Staphylococcus aureus subsp. aureus COL leucyl-tRNA synthetase YP_186641.1 1862816 R 93062 CDS YP_186642.1 57652057 3236034 complement(1865521..1866702) 1 NC_002951.2 identified by match to protein family HMM PF07690; drug transporter 1866702 3236034 SACOL1809 Staphylococcus aureus subsp. aureus COL drug transporter YP_186642.1 1865521 R 93062 CDS YP_186643.1 57652058 3236540 1866812..1867765 1 NC_002951.2 identified by similarity to EGAD:108408; match to protein family HMM PF04055; match to protein family HMM TIGR01212; hypothetical protein 1867765 3236540 SACOL1810 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186643.1 1866812 D 93062 CDS YP_186644.1 57652059 3238704 1867762..1868325 1 NC_002951.2 identified by similarity to OMNI:NTL01BH3288; match to protein family HMM PF06962; hypothetical protein 1868325 3238704 SACOL1811 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186644.1 1867762 D 93062 CDS YP_186645.1 57652060 3238705 complement(1868445..1868945) 1 NC_002951.2 identified by similarity to GP:6651452; match to protein family HMM TIGR01889; repressor of toxins 1868945 rot 3238705 rot Staphylococcus aureus subsp. aureus COL repressor of toxins YP_186645.1 1868445 R 93062 CDS YP_186646.1 57652061 3236541 complement(1870425..1871252) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH3291; lysophospholipase 1871252 3236541 SACOL1814 Staphylococcus aureus subsp. aureus COL lysophospholipase YP_186646.1 1870425 R 93062 CDS YP_186647.1 57652062 3236542 complement(1871255..1871374) 1 NC_002951.2 hypothetical protein 1871374 3236542 SACOL1815 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186647.1 1871255 R 93062 CDS YP_186648.1 57652063 3236543 1871486..1872487 1 NC_002951.2 identified by match to protein family HMM PF01619; proline dehydrogenase 1872487 putA 3236543 putA Staphylococcus aureus subsp. aureus COL proline dehydrogenase YP_186648.1 1871486 D 93062 CDS YP_186649.1 57652064 3236544 complement(1872609..1873073) 1 NC_002951.2 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 1873073 ribH 3236544 ribH Staphylococcus aureus subsp. aureus COL 6,7-dimethyl-8-ribityllumazine synthase YP_186649.1 1872609 R 93062 CDS YP_186650.1 57652065 3236545 complement(1873086..1874267) 1 NC_002951.2 identified by similarity to EGAD:14797; match to protein family HMM PF00925; match to protein family HMM PF00926; match to protein family HMM TIGR00505; match to protein family HMM TIGR00506; riboflavin biosynthesis protein 1874267 ribBA 3236545 ribBA Staphylococcus aureus subsp. aureus COL riboflavin biosynthesis protein YP_186650.1 1873086 R 93062 CDS YP_186651.1 57652066 3236005 complement(1874278..1874910) 1 NC_002951.2 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1874910 ribE 3236005 ribE Staphylococcus aureus subsp. aureus COL riboflavin synthase subunit alpha YP_186651.1 1874278 R 93062 CDS YP_186652.1 57652067 3236006 complement(1874917..1875960) 1 NC_002951.2 identified by similarity to EGAD:14315; match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00326; riboflavin biosynthesis protein RibD 1875960 ribD 3236006 ribD Staphylococcus aureus subsp. aureus COL riboflavin biosynthesis protein RibD YP_186652.1 1874917 R 93062 CDS YP_186653.1 57652068 3236007 complement(1876441..1877943) 1 NC_002951.2 identified by similarity to GB:AAO05041.1; hypothetical protein 1877943 3236007 SACOL1821 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186653.1 1876441 R 93062 CDS YP_186654.1 57652069 3236008 1878466..1878780 1 NC_002951.2 identified by similarity to EGAD:10168; match to protein family HMM PF01022; arsenical resistance operon repressor 1878780 arsR 3236008 arsR Staphylococcus aureus subsp. aureus COL arsenical resistance operon repressor YP_186654.1 1878466 D 93062 CDS YP_186655.1 57652070 3236009 1878780..1880072 1 NC_002951.2 identified by similarity to OMNI:NTL02EC4342; match to protein family HMM PF02040; match to protein family HMM TIGR00935; arsenical pump membrane protein 1880072 arsB 3236009 arsB Staphylococcus aureus subsp. aureus COL arsenical pump membrane protein YP_186655.1 1878780 D 93062 CDS YP_186656.1 57652071 3236010 1880090..1880485 1 NC_002951.2 catalyzes the reduction of arsenate to arsenite; also can dephosphorylate tyrosine phosphorylated proteins, aryl phosphates, and acyl phosphates; arsenate reductase 1880485 arsC 3236010 arsC Staphylococcus aureus subsp. aureus COL arsenate reductase YP_186656.1 1880090 D 93062 CDS YP_186657.1 57652072 3236011 complement(1880780..1881634) 1 NC_002951.2 identified by match to protein family HMM PF01832; N-acetylmuramoyl-L-alanine amidase 1881634 3236011 SACOL1825 Staphylococcus aureus subsp. aureus COL N-acetylmuramoyl-L-alanine amidase YP_186657.1 1880780 R 93062 CDS YP_186658.1 57652073 3235998 complement(1881910..1882134) 1 NC_002951.2 identified by similarity to GB:AAN32737.1; hypothetical protein 1882134 3235998 SACOL1826 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186658.1 1881910 R 93062 CDS YP_186659.1 57652074 3235999 1882333..1882803 1 NC_002951.2 identified by match to protein family HMM PF04542; RNA polymerase sigma-70 family protein 1882803 3235999 SACOL1827 Staphylococcus aureus subsp. aureus COL RNA polymerase sigma-70 family protein YP_186659.1 1882333 D 93062 CDS YP_186660.1 57652075 3236000 1882916..1883359 1 NC_002951.2 identified by similarity to GB:AAN32735.1; hypothetical protein 1883359 3236000 SACOL1828 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186660.1 1882916 D 93062 CDS YP_186661.1 57652076 3236001 complement(1883346..1883789) 1 NC_002951.2 identified by similarity to GB:AAO05047.1; hypothetical protein 1883789 3236001 SACOL1829 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186661.1 1883346 R 93062 CDS YP_186662.1 57652077 3236002 1884085..1884720 1 NC_002951.2 identified by match to protein family HMM PF02517; hypothetical protein 1884720 3236002 SACOL1830 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186662.1 1884085 D 93062 CDS YP_186663.1 57652078 3236003 complement(1885160..1885873) 1 NC_002951.2 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase 1885873 tal 3236003 tal Staphylococcus aureus subsp. aureus COL translaldolase YP_186663.1 1885160 R 93062 CDS YP_186664.1 57652079 3236004 1886613..1887056 1 NC_002951.2 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1887056 crcB 3236004 crcB Staphylococcus aureus subsp. aureus COL camphor resistance protein CrcB YP_186664.1 1886613 D 93062 CDS YP_186665.1 57652080 3237535 1887053..1887406 1 NC_002951.2 identified by match to protein family HMM PF02537; crcB family protein 1887406 3237535 SACOL1833 Staphylococcus aureus subsp. aureus COL crcB family protein YP_186665.1 1887053 D 93062 CDS YP_186666.1 57652081 3237537 complement(1889489..1890322) 1 NC_002951.2 identified by match to protein family HMM PF00248; aldo/keto reductase oxidoreductase 1890322 3237537 SACOL1835 Staphylococcus aureus subsp. aureus COL aldo/keto reductase oxidoreductase YP_186666.1 1889489 R 93062 CDS YP_186667.1 57652082 3237538 complement(1890534..1891442) 1 NC_002951.2 identified by similarity to GB:AAO05056.1; hypothetical protein 1891442 3237538 SACOL1836 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186667.1 1890534 R 93062 CDS YP_186668.1 57650575 3238437 complement(1891567..1892760) 1 NC_002951.2 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1892760 metK 3238437 metK Staphylococcus aureus subsp. aureus COL S-adenosylmethionine synthetase YP_186668.1 1891567 R 93062 CDS YP_186669.1 57650576 3238059 1893131..1894723 1 NC_002951.2 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 1894723 pckA 3238059 pckA Staphylococcus aureus subsp. aureus COL phosphoenolpyruvate carboxykinase YP_186669.1 1893131 D 93062 CDS YP_186670.1 57650577 3238253 complement(1894859..1895344) 1 NC_002951.2 identified by match to protein family HMM PF01797; IS200 family transposase 1895344 3238253 SACOL1839 Staphylococcus aureus subsp. aureus COL IS200 family transposase YP_186670.1 1894859 R 93062 CDS YP_186671.1 57650578 3238600 complement(1895719..1896489) 1 NC_002951.2 identified by similarity to EGAD:108415; hypothetical protein 1896489 3238600 SACOL1840 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186671.1 1895719 R 93062 CDS YP_186672.1 57650579 3236082 complement(1896470..1896949) 1 NC_002951.2 identified by match to protein family HMM PF00293; hypothetical protein 1896949 3236082 SACOL1841 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186672.1 1896470 R 93062 CDS YP_186673.1 57650580 3238245 1897009..1897266 1 NC_002951.2 identified by similarity to OMNI:NTL01BH2832; match to protein family HMM PF01809; match to protein family HMM TIGR00278; hypothetical protein 1897266 3238245 SACOL1842 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186673.1 1897009 D 93062 CDS YP_186674.1 57650581 3238640 complement(1897263..1898264) 1 NC_002951.2 identified by similarity to OMNI:NTL01SA1672; match to protein family HMM TIGR01928; o-succinylbenzoic acid (OSB) synthetase 1898264 3238640 SACOL1843 Staphylococcus aureus subsp. aureus COL o-succinylbenzoic acid (OSB) synthetase YP_186674.1 1897263 R 93062 CDS YP_186675.1 57650582 3237284 complement(1898269..1899747) 1 NC_002951.2 identified by similarity to EGAD:102199; match to protein family HMM PF00501; match to protein family HMM TIGR01923; O-succinylbenzoic acid--CoA ligase 1899747 3237284 SACOL1844 Staphylococcus aureus subsp. aureus COL O-succinylbenzoic acid--CoA ligase YP_186675.1 1898269 R 93062 CDS YP_186676.1 57650583 3237285 complement(1899906..1900388) 1 NC_002951.2 hypothetical protein 1900388 3237285 SACOL1845 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186676.1 1899906 R 93062 CDS YP_186677.1 57650584 3238325 1900664..1901314 1 NC_002951.2 hypothetical protein 1901314 3238325 SACOL1846 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186677.1 1900664 D 93062 CDS YP_186678.1 57650585 3238698 1901395..1902390 1 NC_002951.2 identified by similarity to EGAD:108623; hypothetical protein 1902390 3238698 SACOL1847 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186678.1 1901395 D 93062 CDS YP_186679.1 57650586 3237958 1902466..1903092 1 NC_002951.2 hypothetical protein 1903092 3237958 SACOL1848 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186679.1 1902466 D 93062 CDS YP_186680.1 57650587 3237810 1903133..1903477 1 NC_002951.2 hypothetical protein 1903477 3237810 SACOL1849 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186680.1 1903133 D 93062 CDS YP_186681.1 57650588 3237618 1903575..1904126 1 NC_002951.2 hypothetical protein 1904126 3237618 SACOL1850 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186681.1 1903575 D 93062 CDS YP_186682.1 57650589 3237619 complement(1904344..1904985) 1 NC_002951.2 hypothetical protein 1904985 3237619 SACOL1851 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186682.1 1904344 R 93062 CDS YP_186683.1 57650590 3236121 complement(1905286..1905462) 1 NC_002951.2 hypothetical protein 1905462 3236121 SACOL1853 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186683.1 1905286 R 93062 CDS YP_186684.1 57650591 3238137 complement(1905473..1905856) 1 NC_002951.2 hypothetical protein 1905856 3238137 SACOL1854 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186684.1 1905473 R 93062 CDS YP_186685.1 57650592 3238322 complement(1907606..1907983) 1 NC_002951.2 hypothetical protein 1907983 3238322 SACOL1857 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186685.1 1907606 R 93062 CDS YP_186686.1 57650593 3237142 complement(1908504..1909064) 1 NC_002951.2 hypothetical protein 1909064 3237142 SACOL1858 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186686.1 1908504 R 93062 CDS YP_186687.1 57650594 3237780 complement(1909269..1912319) 1 NC_002951.2 hypothetical protein 1912319 3237780 SACOL1859 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186687.1 1909269 R 93062 CDS YP_186688.1 57650595 3237336 complement(1912386..1912616) 1 NC_002951.2 hypothetical protein 1912616 3237336 SACOL1860 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186688.1 1912386 R 93062 CDS YP_186689.1 57650596 3237806 complement(1913466..1914665) 1 NC_002951.2 identified by match to protein family HMM PF01420; type I restriction-modification enzyme, S subunit, EcoA family protein 1914665 hsdS 3237806 hsdS Staphylococcus aureus subsp. aureus COL type I restriction-modification enzyme, S subunit, EcoA family protein YP_186689.1 1913466 R 93062 CDS YP_186690.1 57650597 3237807 complement(1914658..1916214) 1 NC_002951.2 identified by match to protein family HMM PF02384; match to protein family HMM PF02506; match to protein family HMM TIGR00497; type I restriction-modification system, M subunit 1916214 hsdM2 3237807 hsdM2 Staphylococcus aureus subsp. aureus COL type I restriction-modification system, M subunit YP_186690.1 1914658 R 93062 CDS YP_186691.1 57650598 3237975 complement(1916378..1916512) 1 NC_002951.2 hypothetical protein 1916512 3237975 SACOL1863 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186691.1 1916378 R 93062 CDS YP_186692.1 57650599 3236088 complement(1916577..1917296) 1 NC_002951.2 identified by similarity to OMNI:SA1864; match to protein family HMM PF00089; serine protease SplF 1917296 3236088 SACOL1864 Staphylococcus aureus subsp. aureus COL serine protease SplF YP_186692.1 1916577 R 93062 CDS YP_186693.1 57650600 3237760 complement(1917447..1918163) 1 NC_002951.2 identified by similarity to OMNI:SA1865; match to protein family HMM PF00089; serine protease SplE 1918163 3237760 SACOL1865 Staphylococcus aureus subsp. aureus COL serine protease SplE YP_186693.1 1917447 R 93062 CDS YP_186694.1 57650601 3237918 complement(1918321..1919040) 1 NC_002951.2 identified by similarity to OMNI:NTL01SA1687; match to protein family HMM PF00089; serine protease SplD 1919040 3237918 SACOL1866 Staphylococcus aureus subsp. aureus COL serine protease SplD YP_186694.1 1918321 R 93062 CDS YP_186695.1 57650602 3236101 complement(1919161..1919880) 1 NC_002951.2 identified by match to protein family HMM PF00089; serine protease SplC 1919880 splC 3236101 splC Staphylococcus aureus subsp. aureus COL serine protease SplC YP_186695.1 1919161 R 93062 CDS YP_186696.1 57650603 3237835 complement(1919938..1920660) 1 NC_002951.2 identified by similarity to OMNI:SA1868; match to protein family HMM PF00089; serine protease SplB 1920660 splB 3237835 splB Staphylococcus aureus subsp. aureus COL serine protease SplB YP_186696.1 1919938 R 93062 CDS YP_186697.1 57650604 3237977 complement(1920785..1921501) 1 NC_002951.2 identified by similarity to GP:9739156; match to protein family HMM PF00089; serine protease SplA 1921501 splA 3237977 splA Staphylococcus aureus subsp. aureus COL serine protease SplA YP_186697.1 1920785 R 93062 CDS YP_186698.1 57650605 3236330 1922465..1923031 1 NC_002951.2 hypothetical protein 1923031 3236330 SACOL1870 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186698.1 1922465 D 93062 CDS YP_186699.1 57650606 3237295 complement(1923505..1924203) 1 NC_002951.2 identified by similarity to EGAD:41184; epidermin immunity protein F 1924203 epiG 3237295 epiG Staphylococcus aureus subsp. aureus COL epidermin immunity protein F YP_186699.1 1923505 R 93062 CDS YP_186700.1 57650607 3237296 complement(1924200..1924961) 1 NC_002951.2 identified by similarity to EGAD:41183; epidermin immunity protein F 1924961 epiE 3237296 epiE Staphylococcus aureus subsp. aureus COL epidermin immunity protein F YP_186700.1 1924200 R 93062 CDS YP_186701.1 57650608 3237162 complement(1924958..1925650) 1 NC_002951.2 identified by similarity to EGAD:41182; match to protein family HMM PF00005; epidermin immunity protein F 1925650 epiF 3237162 epiF Staphylococcus aureus subsp. aureus COL epidermin immunity protein F YP_186701.1 1924958 R 93062 CDS YP_186702.1 57650609 3237868 complement(1925673..1927046) 1 NC_002951.2 identified by similarity to EGAD:8533; match to protein family HMM PF00082; epidermin leader peptide processing serine protease EpiP 1927046 epiP 3237868 epiP Staphylococcus aureus subsp. aureus COL epidermin leader peptide processing serine protease EpiP YP_186702.1 1925673 R 93062 CDS YP_186703.1 57650610 3237638 complement(1927056..1927574) 1 NC_002951.2 identified by similarity to EGAD:10889; match to protein family HMM PF02441; epidermin biosynthesis protein EpiD 1927574 epiD 3237638 epiD Staphylococcus aureus subsp. aureus COL epidermin biosynthesis protein EpiD YP_186703.1 1927056 R 93062 CDS YP_186704.1 57650611 3237151 complement(1928827..1931820) 1 NC_002951.2 identified by similarity to EGAD:6172; match to protein family HMM PF04737; match to protein family HMM PF04738; epidermin biosynthesis protein EpiB 1931820 epiB 3237151 epiB Staphylococcus aureus subsp. aureus COL epidermin biosynthesis protein EpiB YP_186704.1 1928827 R 93062 CDS YP_186705.1 57650612 3237579 complement(1931885..1932028) 1 NC_002951.2 identified by similarity to EGAD:6281; match to protein family HMM PF02052; lantibiotic epidermin precursor EpiA 1932028 epiA 3237579 epiA Staphylococcus aureus subsp. aureus COL lantibiotic epidermin precursor EpiA YP_186705.1 1931885 R 93062 CDS YP_186706.1 57650613 3237266 1932920..1934239 1 NC_002951.2 identified by similarity to EGAD:13897; match to protein family HMM PF01610; IS1181 transposase 1934239 3237266 SACOL1879 Staphylococcus aureus subsp. aureus COL IS1181 transposase YP_186706.1 1932920 D 93062 CDS YP_186707.1 57650614 3236709 complement(1934671..1935654) 1 NC_002951.2 identified by similarity to GP:2765304; match to protein family HMM PF01117; match to protein family HMM TIGR01002; leukotoxin LukD 1935654 lukD 3236709 lukD Staphylococcus aureus subsp. aureus COL leukotoxin LukD YP_186707.1 1934671 R 93062 CDS YP_186708.1 57650615 3237836 complement(1935656..1936591) 1 NC_002951.2 identified by similarity to EGAD:22934; match to protein family HMM PF01117; match to protein family HMM TIGR01002; leukotoxin LukE 1936591 lukE 3237836 lukE Staphylococcus aureus subsp. aureus COL leukotoxin LukE YP_186708.1 1935656 R 93062 CDS YP_186709.1 57650616 3237605 1937391..1937930 1 NC_002951.2 hypothetical protein 1937930 3237605 SACOL1882 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186709.1 1937391 D 93062 CDS YP_186710.1 57650617 3237930 1937943..1938731 1 NC_002951.2 hypothetical protein 1938731 3237930 SACOL1883 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186710.1 1937943 D 93062 CDS YP_186711.1 57650618 3237931 complement(1941188..1941742) 1 NC_002951.2 identified by similarity to EGAD:109412; hypothetical protein 1941742 3237931 SACOL1885 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186711.1 1941188 R 93062 CDS YP_186712.1 57650619 3237820 1941836..1942063 1 NC_002951.2 hypothetical protein 1942063 3237820 SACOL1886 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186712.1 1941836 D 93062 CDS YP_186713.1 57650620 3237144 complement(1942065..1943465) 1 NC_002951.2 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX; protoporphyrinogen oxidase 1943465 hemG 3237144 hemG Staphylococcus aureus subsp. aureus COL protoporphyrinogen oxidase YP_186713.1 1942065 R 93062 CDS YP_186714.1 57650621 3236274 complement(1943489..1944412) 1 NC_002951.2 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1944412 hemH 3236274 hemH Staphylococcus aureus subsp. aureus COL ferrochelatase YP_186714.1 1943489 R 93062 CDS YP_186715.1 57650622 3237987 complement(1944470..1945507) 1 NC_002951.2 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 1945507 hemE 3237987 hemE Staphylococcus aureus subsp. aureus COL uroporphyrinogen decarboxylase YP_186715.1 1944470 R 93062 CDS YP_186716.1 57650623 3237963 complement(1945497..1945607) 1 NC_002951.2 hypothetical protein 1945607 3237963 SACOL1890 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186716.1 1945497 R 93062 CDS YP_186717.1 57650624 3236288 1945770..1946273 1 NC_002951.2 identified by similarity to OMNI:SA1891; RNAIII-activating protein TRAP 1946273 3236288 SACOL1891 Staphylococcus aureus subsp. aureus COL RNAIII-activating protein TRAP YP_186717.1 1945770 D 93062 CDS YP_186718.1 57650625 3237832 complement(1946397..1947620) 1 NC_002951.2 identified by match to protein family HMM PF05975; hypothetical protein 1947620 3237832 SACOL1892 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186718.1 1946397 R 93062 CDS YP_186719.1 57650626 3237833 complement(1947613..1948353) 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1948353 3237833 SACOL1893 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_186719.1 1947613 R 93062 CDS YP_186720.1 57650627 3237861 1948487..1948909 1 NC_002951.2 identified by match to protein family HMM PF01230; HIT family protein 1948909 3237861 SACOL1894 Staphylococcus aureus subsp. aureus COL HIT family protein YP_186720.1 1948487 D 93062 CDS YP_186721.1 57650628 3237299 1949051..1949416 1 NC_002951.2 identified by similarity to GB:AAO05118.1; hypothetical protein 1949416 3237299 SACOL1895 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186721.1 1949051 D 93062 CDS YP_186722.1 57650629 3237905 1950149..1950706 1 NC_002951.2 identified by similarity to OMNI:NTL01BH1184; hypothetical protein 1950706 3237905 SACOL1896 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186722.1 1950149 D 93062 CDS YP_186723.1 57650630 3237278 1950911..1951873 1 NC_002951.2 identified by similarity to EGAD:7364; match to protein family HMM PF00639; protein export protein PrsA 1951873 3237278 SACOL1897 Staphylococcus aureus subsp. aureus COL protein export protein PrsA YP_186723.1 1950911 D 93062 CDS YP_186724.1 57650631 3237279 complement(1951994..1952935) 1 NC_002951.2 catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates; 3'-5' exoribonuclease YhaM 1952935 cbf1 3237279 cbf1 Staphylococcus aureus subsp. aureus COL 3'-5' exoribonuclease YhaM YP_186724.1 1951994 R 93062 CDS YP_186725.1 57650632 3236128 complement(1952932..1955868) 1 NC_002951.2 identified by similarity to GB:AAO05123.1; hypothetical protein 1955868 3236128 SACOL1899 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186725.1 1952932 R 93062 CDS YP_186726.1 57650633 3237667 complement(1955858..1957054) 1 NC_002951.2 identified by match to protein family HMM PF00149; DNA repair exonuclease 1957054 3237667 SACOL1900 Staphylococcus aureus subsp. aureus COL DNA repair exonuclease YP_186726.1 1955858 R 93062 CDS YP_186727.1 57650634 3237950 complement(1957826..1958170) 1 NC_002951.2 identified by similarity to EGAD:108585; match to protein family HMM PF06133; hypothetical protein 1958170 3237950 SACOL1902 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186727.1 1957826 R 93062 CDS YP_186728.1 57650635 3237342 complement(1958239..1959363) 1 NC_002951.2 identified by match to protein family HMM PF04286; hypothetical protein 1959363 3237342 SACOL1903 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186728.1 1958239 R 93062 CDS YP_186729.1 57650636 3237895 complement(1959542..1960006) 1 NC_002951.2 identified by match to protein family HMM PF01381; transcriptional regulator 1960006 3237895 SACOL1904 Staphylococcus aureus subsp. aureus COL transcriptional regulator YP_186729.1 1959542 R 93062 CDS YP_186730.1 57650637 3237896 complement(1960362..1960985) 1 NC_002951.2 identified by similarity to OMNI:NTL01SA1761; match to protein family HMM PF00072; match to protein family HMM PF00196; LuxR family DNA-binding response regulator 1960985 3237896 SACOL1905 Staphylococcus aureus subsp. aureus COL LuxR family DNA-binding response regulator YP_186730.1 1960362 R 93062 CDS YP_186731.1 57650638 3237318 complement(1961007..1962119) 1 NC_002951.2 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; sensor histidine kinase 1962119 3237318 SACOL1906 Staphylococcus aureus subsp. aureus COL sensor histidine kinase YP_186731.1 1961007 R 93062 CDS YP_186732.1 57650639 3237136 1962282..1963103 1 NC_002951.2 identified by match to protein family HMM PF00849; ribosomal large subunit pseudouridine synthase D 1963103 3237136 SACOL1907 Staphylococcus aureus subsp. aureus COL ribosomal large subunit pseudouridine synthase D YP_186732.1 1962282 D 93062 CDS YP_186733.1 57650640 3237674 complement(1963566..1964951) 1 NC_002951.2 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1964951 fumC 3237674 fumC Staphylococcus aureus subsp. aureus COL fumarate hydratase YP_186733.1 1963566 R 93062 CDS YP_186734.1 57650641 3237636 complement(1965147..1965542) 1 NC_002951.2 identified by similarity to GB:AAO05132.1; hypothetical protein 1965542 3237636 SACOL1909 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186734.1 1965147 R 93062 CDS YP_186735.1 57650642 3237280 1965661..1966023 1 NC_002951.2 hypothetical protein 1966023 3237280 SACOL1910 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186735.1 1965661 D 93062 CDS YP_186736.1 57650643 3237281 complement(1966319..1966471) 1 NC_002951.2 identified by similarity to GB:AAO05133.1; hypothetical protein 1966471 3237281 SACOL1911 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186736.1 1966319 R 93062 CDS YP_186737.1 57650644 3236086 complement(1966496..1967095) 1 NC_002951.2 hypothetical protein 1967095 3236086 SACOL1912 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186737.1 1966496 R 93062 CDS YP_186738.1 57650645 3237923 complement(1967254..1967724) 1 NC_002951.2 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00185; RNA methyltransferase 1967724 3237923 SACOL1913 Staphylococcus aureus subsp. aureus COL RNA methyltransferase YP_186738.1 1967254 R 93062 CDS YP_186739.1 57650646 3237276 complement(1967729..1968856) 1 NC_002951.2 identified by match to protein family HMM PF00037; match to protein family HMM TIGR00276; iron-sulfur cluster-binding protein 1968856 3237276 SACOL1914 Staphylococcus aureus subsp. aureus COL iron-sulfur cluster-binding protein YP_186739.1 1967729 R 93062 CDS YP_186740.1 57650647 3237990 complement(1969007..1969735) 1 NC_002951.2 identified by match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 1969735 3237990 SACOL1915 Staphylococcus aureus subsp. aureus COL amino acid ABC transporter ATP-binding protein YP_186740.1 1969007 R 93062 CDS YP_186741.1 57650648 3237991 complement(1969722..1971179) 1 NC_002951.2 identified by match to protein family HMM PF00497; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease/substrate-binding protein 1971179 3237991 SACOL1916 Staphylococcus aureus subsp. aureus COL amino acid ABC transporter permease/substrate-binding protein YP_186741.1 1969722 R 93062 CDS YP_186742.1 57650649 3237559 complement(1971437..1972498) 1 NC_002951.2 identified by match to protein family HMM PF02378; PTS system, IIC component 1972498 3237559 SACOL1917 Staphylococcus aureus subsp. aureus COL PTS system, IIC component YP_186742.1 1971437 R 93062 CDS YP_186743.1 57650650 3238022 1972991..1974310 1 NC_002951.2 identified by similarity to EGAD:13897; match to protein family HMM PF01610; IS1181 transposase 1974310 3238022 SACOL1918 Staphylococcus aureus subsp. aureus COL IS1181 transposase YP_186743.1 1972991 D 93062 CDS YP_186744.1 57650651 3238214 complement(1982818..1983264) 1 NC_002951.2 identified by match to protein family HMM PF01475; FUR family transcriptional regulator 1983264 3238214 SACOL1919 Staphylococcus aureus subsp. aureus COL FUR family transcriptional regulator YP_186744.1 1982818 R 93062 CDS YP_186745.1 57650652 3238215 complement(1983361..1984311) 1 NC_002951.2 identified by match to protein family HMM PF00389; match to protein family HMM PF02826; D-isomer specific 2-hydroxyacid dehydrogenase 1984311 3238215 SACOL1920 Staphylococcus aureus subsp. aureus COL D-isomer specific 2-hydroxyacid dehydrogenase YP_186745.1 1983361 R 93062 CDS YP_186746.1 57650653 3238210 complement(1984317..1984772) 1 NC_002951.2 identified by match to protein family HMM PF00578; bacterioferritin comigratory protein 1984772 bcp 3238210 bcp Staphylococcus aureus subsp. aureus COL bacterioferritin comigratory protein YP_186746.1 1984317 R 93062 CDS YP_186747.1 57652083 3237539 1984853..1986142 1 NC_002951.2 converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate; glutamate-1-semialdehyde aminotransferase 1986142 hemL2 3237539 hemL2 Staphylococcus aureus subsp. aureus COL glutamate-1-semialdehyde aminotransferase YP_186747.1 1984853 D 93062 CDS YP_186748.1 57652084 3237540 1986435..1987529 1 NC_002951.2 identified by match to protein family HMM PF06081; hypothetical protein 1987529 3237540 SACOL1923 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186748.1 1986435 D 93062 CDS YP_186749.1 57652085 3237541 complement(1987720..1989456) 1 NC_002951.2 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; toxin exporting ABC transporter permease/ATP-binding protein 1989456 3237541 SACOL1924 Staphylococcus aureus subsp. aureus COL toxin exporting ABC transporter permease/ATP-binding protein YP_186749.1 1987720 R 93062 CDS YP_186750.1 57652086 3237526 complement(1989747..1990289) 1 NC_002951.2 identified by match to protein family HMM PF04167; hypothetical protein 1990289 3237526 SACOL1925 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186750.1 1989747 R 93062 CDS YP_186751.1 57652087 3237527 complement(1990591..1991628) 1 NC_002951.2 identified by similarity to EGAD:19424; match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084; A/G-specific adenine glycosylase 1991628 mutY 3237527 mutY Staphylococcus aureus subsp. aureus COL A/G-specific adenine glycosylase YP_186751.1 1990591 R 93062 CDS YP_186752.1 57652088 3237528 1991780..1992757 1 NC_002951.2 identified by match to protein family HMM PF04307; hypothetical protein 1992757 3237528 SACOL1927 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186752.1 1991780 D 93062 CDS YP_186753.1 57652089 3237529 complement(1993018..1993854) 1 NC_002951.2 hypothetical protein 1993854 3237529 SACOL1928 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186753.1 1993018 R 93062 CDS YP_186754.1 57652090 3237530 complement(1993863..1995380) 1 NC_002951.2 ABC transporter ATP-binding protein 1995380 3237530 SACOL1929 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_186754.1 1993863 R 93062 CDS YP_186755.1 57652091 3237531 complement(1995395..1995709) 1 NC_002951.2 hypothetical protein 1995709 3237531 SACOL1930 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186755.1 1995395 R 93062 CDS YP_186756.1 57652092 3237532 complement(1995687..1996505) 1 NC_002951.2 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1996505 recX 3237532 recX Staphylococcus aureus subsp. aureus COL recombination regulator RecX YP_186756.1 1995687 R 93062 CDS YP_186757.1 57652093 3237533 complement(1996766..1997575) 1 NC_002951.2 monofunctional; catalyzes the elongation of glycan strands in cell wall biosynthesis; glycosyltransferase 1997575 3237533 SACOL1932 Staphylococcus aureus subsp. aureus COL glycosyltransferase YP_186757.1 1996766 R 93062 CDS YP_186758.1 57652094 3237519 complement(1997916..1998431) 1 NC_002951.2 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382; ThiJ/PfpI family protein 1998431 3237519 SACOL1933 Staphylococcus aureus subsp. aureus COL ThiJ/PfpI family protein YP_186758.1 1997916 R 93062 CDS YP_186759.1 57652095 3237520 complement(1998562..1998723) 1 NC_002951.2 hypothetical protein 1998723 3237520 SACOL1934 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186759.1 1998562 R 93062 CDS YP_186760.1 57652096 3237521 1998947..2000098 1 NC_002951.2 identified by similarity to GP:10173504; match to protein family HMM PF04055; hypothetical protein 2000098 3237521 SACOL1935 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186760.1 1998947 D 93062 CDS YP_186761.1 57652097 3237522 complement(2000358..2000888) 1 NC_002951.2 identified by match to protein family HMM PF03061; hypothetical protein 2000888 3237522 SACOL1936 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186761.1 2000358 R 93062 CDS YP_186762.1 57652098 3237523 complement(2000978..2002234) 1 NC_002951.2 identified by similarity to SP:Q9X4A7; match to protein family HMM PF02073; aminopeptidase PepS 2002234 pepS 3237523 pepS Staphylococcus aureus subsp. aureus COL aminopeptidase PepS YP_186762.1 2000978 R 93062 CDS YP_186763.1 57652099 3237524 complement(2002237..2002443) 1 NC_002951.2 identified by match to protein family HMM PF06569; hypothetical protein 2002443 3237524 SACOL1938 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186763.1 2002237 R 93062 CDS YP_186764.1 57652100 3237525 2002584..2003048 1 NC_002951.2 identified by match to protein family HMM PF01451; phosphotyrosine protein phosphatase 2003048 3237525 SACOL1939 Staphylococcus aureus subsp. aureus COL phosphotyrosine protein phosphatase YP_186764.1 2002584 D 93062 CDS YP_186765.1 57652101 3237511 2003055..2003330 1 NC_002951.2 identified by similarity to GB:AAO05166.1; hypothetical protein 2003330 3237511 SACOL1940 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186765.1 2003055 D 93062 CDS YP_186766.1 57652102 3237512 2003608..2004825 1 NC_002951.2 identified by match to protein family HMM PF03631; match to protein family HMM TIGR00765; ribonuclease BN 2004825 3237512 SACOL1941 Staphylococcus aureus subsp. aureus COL ribonuclease BN YP_186766.1 2003608 D 93062 CDS YP_186767.1 57652103 3237513 complement(2004941..2005570) 1 NC_002951.2 identified by similarity to GP:9501772; similarity to OMNI:NTL01SA1761; match to protein family HMM PF00072; match to protein family HMM PF00196; DNA-binding response regulator VraR 2005570 vraR 3237513 vraR Staphylococcus aureus subsp. aureus COL DNA-binding response regulator VraR YP_186767.1 2004941 R 93062 CDS YP_186768.1 57652104 3237514 complement(2005560..2006603) 1 NC_002951.2 identified by similarity to OMNI:NTL02SA1888; match to protein family HMM PF02518; sensor histidine kinase VraS 2006603 vraS 3237514 vraS Staphylococcus aureus subsp. aureus COL sensor histidine kinase VraS YP_186768.1 2005560 R 93062 CDS YP_186769.1 57652105 3237515 complement(2006600..2007301) 1 NC_002951.2 hypothetical protein 2007301 3237515 SACOL1944 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186769.1 2006600 R 93062 CDS YP_186770.1 57652106 3237516 complement(2007316..2007702) 1 NC_002951.2 hypothetical protein 2007702 3237516 SACOL1945 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186770.1 2007316 R 93062 CDS YP_186771.1 57652107 3237517 complement(2007919..2008677) 1 NC_002951.2 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 2008677 3237517 SACOL1946 Staphylococcus aureus subsp. aureus COL methionine aminopeptidase YP_186771.1 2007919 R 93062 CDS YP_186772.1 57652108 3237518 2009205..2010191 1 NC_002951.2 hypothetical protein 2010191 3237518 SACOL1947 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186772.1 2009205 D 93062 CDS YP_186773.1 57652109 3237503 complement(2010622..2011035) 1 NC_002951.2 hypothetical protein 2011035 3237503 SACOL1948 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186773.1 2010622 R 93062 CDS YP_186774.1 57652110 3237504 complement(2011064..2011174) 1 NC_002951.2 hypothetical protein 2011174 3237504 SACOL1949 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186774.1 2011064 R 93062 CDS YP_186775.1 57652111 3237505 complement(2011260..2011991) 1 NC_002951.2 identified by match to protein family HMM PF07685; cobyric acid synthase 2011991 3237505 SACOL1950 Staphylococcus aureus subsp. aureus COL cobyric acid synthase YP_186775.1 2011260 R 93062 CDS YP_186776.1 57652112 3237506 complement(2011993..2013306) 1 NC_002951.2 Mur ligase 2013306 3237506 SACOL1951 Staphylococcus aureus subsp. aureus COL Mur ligase YP_186776.1 2011993 R 93062 CDS YP_186777.1 57652113 3237507 2013598..2014098 1 NC_002951.2 identified by similarity to EGAD:8114; match to protein family HMM PF00210; ferritins family protein 2014098 3237507 SACOL1952 Staphylococcus aureus subsp. aureus COL ferritins family protein YP_186777.1 2013598 D 93062 CDS YP_186778.1 57652114 3237508 complement(2014180..2014272) 1 NC_002951.2 hypothetical protein 2014272 3237508 SACOL1953 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186778.1 2014180 R 93062 CDS YP_186779.1 57652115 3237509 2014487..2015041 1 NC_002951.2 identified by match to protein family HMM PF00929; exonuclease 2015041 3237509 SACOL1954 Staphylococcus aureus subsp. aureus COL exonuclease YP_186779.1 2014487 D 93062 CDS YP_186780.1 57652116 3237510 complement(2015109..2016179) 1 NC_002951.2 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 2016179 dinP 3237510 dinP Staphylococcus aureus subsp. aureus COL DNA polymerase IV YP_186780.1 2015109 R 93062 CDS YP_186781.1 57652117 3237495 complement(2016426..2016956) 1 NC_002951.2 identified by similarity to GB:AAO05180.1; hypothetical protein 2016956 3237495 SACOL1956 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186781.1 2016426 R 93062 CDS YP_186782.1 57652118 3237496 complement(2017126..2018487) 1 NC_002951.2 identified by match to protein family HMM PF05958; match to protein family HMM TIGR00479; RNA methyltransferase 2018487 3237496 SACOL1957 Staphylococcus aureus subsp. aureus COL RNA methyltransferase YP_186782.1 2017126 R 93062 CDS YP_186783.1 57652119 3237497 complement(2018568..2019515) 1 NC_002951.2 similar to YegS from E. coli; lipid kinase 2019515 3237497 SACOL1958 Staphylococcus aureus subsp. aureus COL lipid kinase YP_186783.1 2018568 R 93062 CDS YP_186784.1 57652120 3237498 complement(2020284..2021711) 1 NC_002951.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 2021711 gatB 3237498 gatB Staphylococcus aureus subsp. aureus COL aspartyl/glutamyl-tRNA amidotransferase subunit B YP_186784.1 2020284 R 93062 CDS YP_186785.1 57652121 3237499 complement(2021724..2023181) 1 NC_002951.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 2023181 gatA 3237499 gatA Staphylococcus aureus subsp. aureus COL aspartyl/glutamyl-tRNA amidotransferase subunit A YP_186785.1 2021724 R 93062 CDS YP_186786.1 57652122 3237500 complement(2023183..2023485) 1 NC_002951.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 2023485 gatC 3237500 gatC Staphylococcus aureus subsp. aureus COL aspartyl/glutamyl-tRNA amidotransferase subunit C YP_186786.1 2023183 R 93062 CDS YP_186787.1 57652123 3237501 2023853..2025391 1 NC_002951.2 identified by similarity to EGAD:107637; match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121; high affinity proline permease 2025391 3237501 SACOL1963 Staphylococcus aureus subsp. aureus COL high affinity proline permease YP_186787.1 2023853 D 93062 CDS YP_186788.1 57650654 3238098 complement(2025480..2026679) 1 NC_002951.2 identified by similarity to GP:20522056; match to protein family HMM PF07537; hypothetical protein 2026679 camS 3238098 camS Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186788.1 2025480 R 93062 CDS YP_186789.1 57650655 3238150 complement(2026692..2028695) 1 NC_002951.2 identified by similarity to SP:O87703; match to protein family HMM PF00533; match to protein family HMM PF01653; match to protein family HMM PF03119; match to protein family HMM PF03120; match to protein family HMM TIGR00575; DNA ligase, NAD-dependent 2028695 ligA 3238150 ligA Staphylococcus aureus subsp. aureus COL DNA ligase, NAD-dependent YP_186789.1 2026692 R 93062 CDS YP_186790.1 57650656 3238182 complement(2028699..2030891) 1 NC_002951.2 identified by similarity to SP:Q53727; match to protein family HMM PF00580; match to protein family HMM TIGR01073; ATP-dependent DNA helicase PcrA 2030891 pcrA 3238182 pcrA Staphylococcus aureus subsp. aureus COL ATP-dependent DNA helicase PcrA YP_186790.1 2028699 R 93062 CDS YP_186791.1 57650657 3238021 complement(2030888..2031580) 1 NC_002951.2 PcrB-like protein; GGGP synthase; member of prenyltransferases that transfer isoprenoid groups to nonisoprenoid acceptors; functions in form GGGP from glycerol-1-phosphate (G-1-P) and geranylgeranyl pyrophosphate (GGPP); important in lipid metabolism and especially important as the ether linkages in archaea are different than those in bacteria; GGGP synthase lies at the branch point for membrane lipid biosynthesis; cytosolic; T acidophilum protein acts as a homodimer while M thermoautotrophicum protein has been reported to function as a pentamer; geranylgeranylglyceryl phosphate synthase 2031580 3238021 SACOL1967 Staphylococcus aureus subsp. aureus COL geranylgeranylglyceryl phosphate synthase YP_186791.1 2030888 R 93062 CDS YP_186792.1 57650658 3238635 complement(2031752..2032054) 1 NC_002951.2 identified by match to protein family HMM PF01371; hypothetical protein 2032054 3238635 SACOL1968 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186792.1 2031752 R 93062 CDS YP_186793.1 57650659 3238180 complement(2032163..2033458) 1 NC_002951.2 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 2033458 purB 3238180 purB Staphylococcus aureus subsp. aureus COL adenylosuccinate lyase YP_186793.1 2032163 R 93062 CDS YP_186794.1 57650660 3238181 2034319..2035485 1 NC_002951.2 identified by similarity to OMNI:SA1056; cysteine protease precursor SspB 2035485 sspB2 3238181 sspB2 Staphylococcus aureus subsp. aureus COL cysteine protease precursor SspB YP_186794.1 2034319 D 93062 CDS YP_186795.1 57650661 3238184 2035516..2035842 1 NC_002951.2 hypothetical protein 2035842 3238184 SACOL1971 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186795.1 2035516 D 93062 CDS YP_186796.1 57650662 3238258 complement(2036134..2036307) 1 NC_002951.2 hypothetical protein 2036307 3238258 SACOL1972 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186796.1 2036134 R 93062 CDS YP_186797.1 57650663 3238039 complement(2036288..2036890) 1 NC_002951.2 hypothetical protein 2036890 3238039 SACOL1973 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186797.1 2036288 R 93062 CDS YP_186798.1 57650664 3238369 complement(2037161..2037982) 1 NC_002951.2 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 2037982 nadE 3238369 nadE Staphylococcus aureus subsp. aureus COL NAD synthetase YP_186798.1 2037161 R 93062 CDS YP_186799.1 57650665 3238409 complement(2037975..2039444) 1 NC_002951.2 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 2039444 3238409 SACOL1975 Staphylococcus aureus subsp. aureus COL nicotinate phosphoribosyltransferase YP_186799.1 2037975 R 93062 CDS YP_186800.1 57650666 3238410 2039628..2040704 1 NC_002951.2 identified by match to protein family HMM PF02898; nitric-oxide synthase, oxygenase subunit 2040704 3238410 SACOL1976 Staphylococcus aureus subsp. aureus COL nitric-oxide synthase, oxygenase subunit YP_186800.1 2039628 D 93062 CDS YP_186801.1 57650667 3238627 2040724..2041518 1 NC_002951.2 identified by similarity to EGAD:17359; similarity to EGAD:29700; match to protein family HMM PF00800; match to protein family HMM PF01842; prephenate dehydratase 2041518 pheA 3238627 pheA Staphylococcus aureus subsp. aureus COL prephenate dehydratase YP_186801.1 2040724 D 93062 CDS YP_186802.1 57650668 3238435 complement(2041543..2041665) 1 NC_002951.2 hypothetical protein 2041665 3238435 SACOL1978 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186802.1 2041543 R 93062 CDS YP_186803.1 57650669 3238267 complement(2041708..2043270) 1 NC_002951.2 identified by match to protein family HMM PF00939; match to protein family HMM TIGR00785; sodium-dependent transporter 2043270 3238267 SACOL1979 Staphylococcus aureus subsp. aureus COL sodium-dependent transporter YP_186803.1 2041708 R 93062 CDS YP_186804.1 57650670 3238268 complement(2043475..2044572) 1 NC_002951.2 hypothetical protein 2044572 3238268 SACOL1980 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186804.1 2043475 R 93062 CDS YP_186805.1 57650671 3238234 2044944..2045504 1 NC_002951.2 identified by match to protein family HMM PF00857; isochorismatase 2045504 3238234 SACOL1981 Staphylococcus aureus subsp. aureus COL isochorismatase YP_186805.1 2044944 D 93062 CDS YP_186806.1 57650672 3238596 2045557..2046486 1 NC_002951.2 catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase 2046486 ppaC 3238596 ppaC Staphylococcus aureus subsp. aureus COL manganese-dependent inorganic pyrophosphatase YP_186806.1 2045557 D 93062 CDS YP_186807.1 57650673 3238087 complement(2046681..2046854) 1 NC_002951.2 hypothetical protein 2046854 3238087 SACOL1983 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186807.1 2046681 R 93062 CDS YP_186808.1 57650674 3238088 2046906..2048285 1 NC_002951.2 identified by match to protein family HMM PF00171; aldehyde dehydrogenase 2048285 aldA2 3238088 aldA2 Staphylococcus aureus subsp. aureus COL aldehyde dehydrogenase YP_186808.1 2046906 D 93062 CDS YP_186809.1 57650675 3238407 complement(2048405..2049433) 1 NC_002951.2 identified by similarity to EGAD:107450; hypothetical protein 2049433 3238407 SACOL1985 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186809.1 2048405 R 93062 CDS YP_186810.1 57650676 3238164 2049703..2050104 1 NC_002951.2 hypothetical protein 2050104 3238164 SACOL1986 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186810.1 2049703 D 93062 CDS YP_186811.1 57650677 3238271 complement(2050677..2050850) 1 NC_002951.2 hypothetical protein 2050850 3238271 SACOL1987 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186811.1 2050677 R 93062 CDS YP_186812.1 57650678 3238272 2051301..2052341 1 NC_002951.2 identified by match to protein family HMM PF03417; hypothetical protein 2052341 3238272 SACOL1988 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186812.1 2051301 D 93062 CDS YP_186813.1 57650679 3238221 complement(2052398..2053240) 1 NC_002951.2 identified by similarity to GB:AAO05216.1; hypothetical protein 2053240 3238221 SACOL1989 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186813.1 2052398 R 93062 CDS YP_186814.1 57650680 3238229 complement(2053237..2053794) 1 NC_002951.2 hypothetical protein 2053794 3238229 SACOL1990 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186814.1 2053237 R 93062 CDS YP_186815.1 57650681 3238230 complement(2053854..2054378) 1 NC_002951.2 identified by similarity to GB:AAO05218.1; hypothetical protein 2054378 3238230 SACOL1991 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186815.1 2053854 R 93062 CDS YP_186816.1 57650682 3238377 2054499..2055062 1 NC_002951.2 identified by similarity to GB:BAC14289.1; hypothetical protein 2055062 3238377 SACOL1992 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186816.1 2054499 D 93062 CDS YP_186817.1 57650683 3238573 complement(2055128..2055868) 1 NC_002951.2 identified by similarity to GB:AAO05220.1; hypothetical protein 2055868 3238573 SACOL1993 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186817.1 2055128 R 93062 CDS YP_186818.1 57650684 3238035 complement(2055868..2056740) 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2056740 3238035 SACOL1994 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_186818.1 2055868 R 93062 CDS YP_186819.1 57650685 3238036 complement(2056737..2057417) 1 NC_002951.2 identified by similarity to GB:AAO05222.1; hypothetical protein 2057417 3238036 SACOL1995 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186819.1 2056737 R 93062 CDS YP_186820.1 57650686 3238316 complement(2057418..2058314) 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2058314 3238316 SACOL1996 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_186820.1 2057418 R 93062 CDS YP_186821.1 57650687 3238638 complement(2058311..2058691) 1 NC_002951.2 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 2058691 3238638 SACOL1997 Staphylococcus aureus subsp. aureus COL GntR family transcriptional regulator YP_186821.1 2058311 R 93062 CDS YP_186822.1 57650688 3238639 complement(2058955..2059131) 1 NC_002951.2 identified by similarity to GB:AAO05225.1; hypothetical protein 2059131 3238639 SACOL1998 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186822.1 2058955 R 93062 CDS YP_186823.1 57650689 3238152 complement(2059374..2059472) 1 NC_002951.2 hypothetical protein 2059472 3238152 SACOL1999 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186823.1 2059374 R 93062 CDS YP_186824.1 57650690 3238405 2059672..2060958 1 NC_002951.2 hypothetical protein 2060958 3238405 SACOL2000 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186824.1 2059672 D 93062 CDS YP_186825.1 57650691 3238647 complement(join(2061282..2061587,2061589..2063337)) 1 NC_002951.2 identified by similarity to GP:8648965; map protein, programmed frameshift 2063337 map 3238647 map Staphylococcus aureus subsp. aureus COL map protein, programmed frameshift YP_186825.1 2061282 R 93062 CDS YP_186826.1 57650692 3238648 2063726..2064718 1 NC_002951.2 identified by similarity to OMNI:SA2003; match to protein family HMM PF03372; phospholipase C 2064718 hlb 3238648 hlb Staphylococcus aureus subsp. aureus COL phospholipase C YP_186826.1 2063726 D 93062 CDS YP_186827.1 57650693 3238002 complement(2064956..2065828) 1 NC_002951.2 identified by match to protein family HMM PF01117; match to protein family HMM TIGR01002; leukocidin subunit precursor 2065828 3238002 SACOL2004 Staphylococcus aureus subsp. aureus COL leukocidin subunit precursor YP_186827.1 2064956 R 93062 CDS YP_186828.1 57650694 3238231 complement(2065994..2067049) 1 NC_002951.2 identified by match to protein family HMM PF01117; Aerolysin/leukocidin family protein 2067049 3238231 SACOL2006 Staphylococcus aureus subsp. aureus COL Aerolysin/leukocidin family protein YP_186828.1 2065994 R 93062 CDS YP_186829.1 57650695 3238212 complement(2069080..2069925) 1 NC_002951.2 identified by similarity to SP:P39887; tetracenomycin polyketide synthesis O-methyltransferase TcmP 2069925 3238212 SACOL2009 Staphylococcus aureus subsp. aureus COL tetracenomycin polyketide synthesis O-methyltransferase TcmP YP_186829.1 2069080 R 93062 CDS YP_186830.1 57650696 3238213 complement(2069987..2070898) 1 NC_002951.2 identified by similarity to EGAD:22102; match to protein family HMM PF01497; iron compound ABC transporter iron compound-binding protein 2070898 3238213 SACOL2010 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter iron compound-binding protein YP_186830.1 2069987 R 93062 CDS YP_186831.1 57650697 3238599 2071059..2072366 1 NC_002951.2 identified by match to protein family HMM PF02386; sodium transport family protein 2072366 3238599 SACOL2011 Staphylococcus aureus subsp. aureus COL sodium transport family protein YP_186831.1 2071059 D 93062 CDS YP_186832.1 57650698 3238122 complement(2073219..2073662) 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 2073662 3238122 SACOL2012 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_186832.1 2073219 R 93062 CDS YP_186833.1 57650699 3238123 complement(2073768..2074205) 1 NC_002951.2 hypothetical protein 2074205 3238123 SACOL2013 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186833.1 2073768 R 93062 CDS YP_186834.1 57650700 3237998 complement(2074523..2075113) 1 NC_002951.2 identified by similarity to EGAD:101510; match to protein family HMM PF03592; phage terminase 2075113 3237998 SACOL2014 Staphylococcus aureus subsp. aureus COL phage terminase YP_186834.1 2074523 R 93062 CDS YP_186835.1 57650701 3238008 complement(2076024..2077640) 1 NC_002951.2 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 2077640 groEL 3238008 groEL Staphylococcus aureus subsp. aureus COL chaperonin GroEL YP_186835.1 2076024 R 93062 CDS YP_186836.1 57650702 3238330 complement(2077716..2078000) 1 NC_002951.2 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 2078000 groES 3238330 groES Staphylococcus aureus subsp. aureus COL co-chaperonin GroES YP_186836.1 2077716 R 93062 CDS YP_186837.1 57650703 3238513 2078175..2078918 1 NC_002951.2 identified by match to protein family HMM PF02517; hypothetical protein 2078918 3238513 SACOL2018 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186837.1 2078175 D 93062 CDS YP_186838.1 57650704 3238514 complement(2078943..2080202) 1 NC_002951.2 identified by similarity to GP:8101009; sdrH protein 2080202 3238514 SACOL2019 Staphylococcus aureus subsp. aureus COL sdrH protein YP_186838.1 2078943 R 93062 CDS YP_186839.1 57650705 3238427 2080399..2081025 1 NC_002951.2 identified by match to protein family HMM PF00881; hypothetical protein 2081025 3238427 SACOL2020 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186839.1 2080399 D 93062 CDS YP_186840.1 57650706 3238161 2081386..2082171 1 NC_002951.2 identified by match to protein family HMM PF00795; carbon-nitrogen family hydrolase 2082171 3238161 SACOL2021 Staphylococcus aureus subsp. aureus COL carbon-nitrogen family hydrolase YP_186840.1 2081386 D 93062 CDS YP_186841.1 57650707 3238162 complement(2082768..2082902) 1 NC_002951.2 Lyses erythrocytes and other mammalian cells; delta-hemolysin 2082902 hld 3238162 hld Staphylococcus aureus subsp. aureus COL delta-hemolysin YP_186841.1 2082768 R 93062 CDS YP_186842.1 57650708 3236539 2083138..2083707 1 NC_002951.2 identified by match to protein family HMM PF04647; accessory gene regulator protein B 2083707 agrB 3236539 agrB Staphylococcus aureus subsp. aureus COL accessory gene regulator protein B YP_186842.1 2083138 D 93062 CDS YP_186843.1 57650709 3236385 2083704..2083844 1 NC_002951.2 identified by similarity to EGAD:18902; match to protein family HMM PF05931; accessory gene regulator protein D 2083844 agrD 3236385 agrD Staphylococcus aureus subsp. aureus COL accessory gene regulator protein D YP_186843.1 2083704 D 93062 CDS YP_186844.1 57650710 3236411 2083869..2085161 1 NC_002951.2 identified by match to protein family HMM PF02518; accessory gene regulator protein C 2085161 argC2 3236411 argC2 Staphylococcus aureus subsp. aureus COL accessory gene regulator protein C YP_186844.1 2083869 D 93062 CDS YP_186845.1 57650711 3236412 2085180..2085896 1 NC_002951.2 identified by similarity to EGAD:16137; match to protein family HMM PF00072; match to protein family HMM PF04397; accessory gene regulator protein A 2085896 agrA 3236412 agrA Staphylococcus aureus subsp. aureus COL accessory gene regulator protein A YP_186845.1 2085180 D 93062 CDS YP_186846.1 57650712 3236366 complement(2086263..2087222) 1 NC_002951.2 identified by similarity to EGAD:129878; match to protein family HMM PF00294; fructokinase 2087222 3236366 SACOL2028 Staphylococcus aureus subsp. aureus COL fructokinase YP_186846.1 2086263 R 93062 CDS YP_186847.1 57650713 3237139 complement(2087219..2088703) 1 NC_002951.2 identified by similarity to EGAD:20672; match to protein family HMM PF00251; match to protein family HMM TIGR01322; sucrose-6-phosphate hydrolase 2088703 cscA 3237139 cscA Staphylococcus aureus subsp. aureus COL sucrose-6-phosphate hydrolase YP_186847.1 2087219 R 93062 CDS YP_186848.1 57650714 3237140 complement(2088852..2089802) 1 NC_002951.2 identified by similarity to EGAD:43207; match to protein family HMM PF00356; match to protein family HMM PF00532; sucrose operon repressor 2089802 scrR 3237140 scrR Staphylococcus aureus subsp. aureus COL sucrose operon repressor YP_186848.1 2088852 R 93062 CDS YP_186849.1 57650715 3237731 complement(2089985..2091235) 1 NC_002951.2 identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836; ammonium transporter family protein 2091235 3237731 SACOL2031 Staphylococcus aureus subsp. aureus COL ammonium transporter family protein YP_186849.1 2089985 R 93062 CDS YP_186850.1 57650716 3236276 complement(2091442..2091666) 1 NC_002951.2 identified by match to protein family HMM PF01206; hypothetical protein 2091666 3236276 SACOL2033 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186850.1 2091442 R 93062 CDS YP_186851.1 57650717 3236277 complement(2091726..2092805) 1 NC_002951.2 identified by match to protein family HMM PF04143; hypothetical protein 2092805 3236277 SACOL2034 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186851.1 2091726 R 93062 CDS YP_186852.1 57650718 3236155 complement(2093109..2093744) 1 NC_002951.2 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 2093744 3236155 SACOL2035 Staphylococcus aureus subsp. aureus COL redox-sensing transcriptional repressor Rex YP_186852.1 2093109 R 93062 CDS YP_186853.1 57650719 3236158 2093997..2095925 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2095925 3236158 SACOL2036 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_186853.1 2093997 D 93062 CDS YP_186854.1 57650720 3236159 2096287..2097897 1 NC_002951.2 identified by match to protein family HMM PF00488; hypothetical protein 2097897 3236159 SACOL2037 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186854.1 2096287 D 93062 CDS YP_186855.1 57650721 3236089 complement(2097999..2099024) 1 NC_002951.2 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 2099024 3236089 SACOL2038 Staphylococcus aureus subsp. aureus COL DNA-binding/iron metalloprotein/AP endonuclease YP_186855.1 2097999 R 93062 CDS YP_186856.1 57650722 3236150 complement(2099017..2099481) 1 NC_002951.2 identified by similarity to PIR:E69786; match to protein family HMM PF00583; match to protein family HMM TIGR01575; ribosomal-protein-alanine acetyltransferase 2099481 3236150 SACOL2039 Staphylococcus aureus subsp. aureus COL ribosomal-protein-alanine acetyltransferase YP_186856.1 2099017 R 93062 CDS YP_186857.1 57650723 3236151 complement(2099454..2100116) 1 NC_002951.2 identified by match to protein family HMM PF00814; hypothetical protein 2100116 3236151 SACOL2040 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186857.1 2099454 R 93062 CDS YP_186858.1 57650724 3236693 complement(2100097..2100531) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH0546; match to protein family HMM PF02367; match to protein family HMM TIGR00150; hypothetical protein 2100531 3236693 SACOL2041 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186858.1 2100097 R 93062 CDS YP_186859.1 57650725 3236694 2101069..2102757 1 NC_002951.2 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 2102757 ilvD 3236694 ilvD Staphylococcus aureus subsp. aureus COL dihydroxy-acid dehydratase YP_186859.1 2101069 D 93062 CDS YP_186860.1 57650726 3236297 2102785..2104554 1 NC_002951.2 identified by match to protein family HMM PF00205; match to protein family HMM PF02776; match to protein family HMM TIGR00118; acetolactate synthase large subunit 2104554 ilvB 3236297 ilvB Staphylococcus aureus subsp. aureus COL acetolactate synthase large subunit YP_186860.1 2102785 D 93062 CDS YP_186861.1 57650727 3237563 2104554..2104808 1 NC_002951.2 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, this subunit subunit is required for full activity and valine sensitivity; also known as acetolactate synthase small; acetolactate synthase 1 regulatory subunit 2104808 3237563 SACOL2044 Staphylococcus aureus subsp. aureus COL acetolactate synthase 1 regulatory subunit YP_186861.1 2104554 D 93062 CDS YP_186862.1 57650728 3238699 2104945..2105949 1 NC_002951.2 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 2105949 ilvC 3238699 ilvC Staphylococcus aureus subsp. aureus COL ketol-acid reductoisomerase YP_186862.1 2104945 D 93062 CDS YP_186863.1 57650729 3238700 2105979..2107508 1 NC_002951.2 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 2107508 leuA 3238700 leuA Staphylococcus aureus subsp. aureus COL 2-isopropylmalate synthase YP_186863.1 2105979 D 93062 CDS YP_186864.1 57650730 3238128 2107511..2108557 1 NC_002951.2 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 2108557 leuB 3238128 leuB Staphylococcus aureus subsp. aureus COL 3-isopropylmalate dehydrogenase YP_186864.1 2107511 D 93062 CDS YP_186865.1 57650731 3238073 2108571..2109941 1 NC_002951.2 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 2109941 leuC 3238073 leuC Staphylococcus aureus subsp. aureus COL isopropylmalate isomerase large subunit YP_186865.1 2108571 D 93062 CDS YP_186866.1 57650732 3238074 2109942..2110514 1 NC_002951.2 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 2110514 leuD 3238074 leuD Staphylococcus aureus subsp. aureus COL isopropylmalate isomerase small subunit YP_186866.1 2109942 D 93062 CDS YP_186867.1 57650733 3238418 2110529..2111797 1 NC_002951.2 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 2111797 ilvA2 3238418 ilvA2 Staphylococcus aureus subsp. aureus COL threonine dehydratase YP_186867.1 2110529 D 93062 CDS YP_186868.1 57650734 3238500 complement(2118160..2118615) 1 NC_002951.2 identified by match to protein family HMM PF03926; hypothetical protein 2118615 3238500 SACOL2052 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186868.1 2118160 R 93062 CDS YP_186869.1 57650735 3238501 complement(2118608..2120758) 1 NC_002951.2 identified by match to protein family HMM PF00575; S1 RNA-binding domain-containing protein 2120758 3238501 SACOL2053 Staphylococcus aureus subsp. aureus COL S1 RNA-binding domain-containing protein YP_186869.1 2118608 R 93062 CDS YP_186870.1 57650736 3237972 complement(2121192..2121962) 1 NC_002951.2 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase; RNA polymerase sigma factor SigB 2121962 rpoF 3237972 rpoF Staphylococcus aureus subsp. aureus COL RNA polymerase sigma factor SigB YP_186870.1 2121192 R 93062 CDS YP_186871.1 57650737 3237973 complement(2121937..2122416) 1 NC_002951.2 binds to sigma-B preventing the formation of an RNA polymerase holoenzyme; serine-protein kinase RsbW 2122416 rsbW 3237973 rsbW Staphylococcus aureus subsp. aureus COL serine-protein kinase RsbW YP_186871.1 2121937 R 93062 CDS YP_186872.1 57650738 3237741 complement(2122418..2122744) 1 NC_002951.2 identified by similarity to SP:P95842; match to protein family HMM PF01740; match to protein family HMM TIGR00377; anti-anti-sigma factor RsbV 2122744 rsbV 3237741 rsbV Staphylococcus aureus subsp. aureus COL anti-anti-sigma factor RsbV YP_186872.1 2122418 R 93062 CDS YP_186873.1 57650739 3237742 complement(2122864..2123865) 1 NC_002951.2 identified by similarity to GP:1729794; match to protein family HMM PF07228; sigma factor B regulator protein 2123865 rsbU 3237742 rsbU Staphylococcus aureus subsp. aureus COL sigma factor B regulator protein YP_186873.1 2122864 R 93062 CDS YP_186874.1 57650740 3238426 complement(2124215..2124577) 1 NC_002951.2 identified by similarity to GP:10834755; match to protein family HMM PF02452; PemK family protein 2124577 3238426 SACOL2058 Staphylococcus aureus subsp. aureus COL PemK family protein YP_186874.1 2124215 R 93062 CDS YP_186875.1 57650741 3238046 complement(2124574..2124744) 1 NC_002951.2 hypothetical protein 2124744 3238046 SACOL2059 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186875.1 2124574 R 93062 CDS YP_186876.1 57650742 3238047 complement(2124829..2125977) 1 NC_002951.2 identified by match to protein family HMM PF00842; match to protein family HMM PF01168; match to protein family HMM TIGR00492; alanine racemase 2125977 alr 3238047 alr Staphylococcus aureus subsp. aureus COL alanine racemase YP_186876.1 2124829 R 93062 CDS YP_186877.1 57650743 3238092 complement(2126043..2126402) 1 NC_002951.2 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 2126402 acpS 3238092 acpS Staphylococcus aureus subsp. aureus COL 4'-phosphopantetheinyl transferase YP_186877.1 2126043 R 93062 CDS YP_186878.1 57650744 3238093 complement(2126406..2126900) 1 NC_002951.2 identified by match to protein family HMM PF03703; hypothetical protein 2126900 3238093 SACOL2062 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186878.1 2126406 R 93062 CDS YP_186879.1 57650745 3238269 complement(2126884..2128467) 1 NC_002951.2 identified by match to protein family HMM PF03703; hypothetical protein 2128467 3238269 SACOL2063 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186879.1 2126884 R 93062 CDS YP_186880.1 57650746 3238270 complement(2128460..2128939) 1 NC_002951.2 hypothetical protein 2128939 3238270 SACOL2064 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186880.1 2128460 R 93062 CDS YP_186881.1 57650747 3238364 complement(2129035..2129151) 1 NC_002951.2 hypothetical protein 2129151 3238364 SACOL2065 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186881.1 2129035 R 93062 CDS YP_186882.1 57650748 3238365 complement(2129148..2129708) 1 NC_002951.2 one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 2129708 kdpC 3238365 kdpC Staphylococcus aureus subsp. aureus COL potassium-transporting ATPase subunit C YP_186882.1 2129148 R 93062 CDS YP_186883.1 57650749 3238586 complement(2129728..2131755) 1 NC_002951.2 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 2131755 kdpB 3238586 kdpB Staphylococcus aureus subsp. aureus COL potassium-transporting ATPase subunit B YP_186883.1 2129728 R 93062 CDS YP_186884.1 57650750 3238587 complement(2131774..2133450) 1 NC_002951.2 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 2133450 kdpA 3238587 kdpA Staphylococcus aureus subsp. aureus COL potassium-transporting ATPase subunit A YP_186884.1 2131774 R 93062 CDS YP_186885.1 57650751 3238085 complement(2133474..2133584) 1 NC_002951.2 identified by match to protein family HMM TIGR02115; K+-transporting ATPase, F subunit 2133584 kdpF 3238085 kdpF Staphylococcus aureus subsp. aureus COL K+-transporting ATPase, F subunit YP_186885.1 2133474 R 93062 CDS YP_186886.1 57650752 3238086 2133722..2136379 1 NC_002951.2 identified by similarity to EGAD:149594; match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF02702; sensor histidine kinase KdpD 2136379 kdpD 3238086 kdpD Staphylococcus aureus subsp. aureus COL sensor histidine kinase KdpD YP_186886.1 2133722 D 93062 CDS YP_186887.1 57650753 3238112 2136379..2137074 1 NC_002951.2 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator KdpE 2137074 kdpE 3238112 kdpE Staphylococcus aureus subsp. aureus COL DNA-binding response regulator KdpE YP_186887.1 2136379 D 93062 CDS YP_186888.1 57650754 3238041 complement(2137443..2138963) 1 NC_002951.2 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; DEAD/DEAH box helicase 2138963 3238041 SACOL2072 Staphylococcus aureus subsp. aureus COL DEAD/DEAH box helicase YP_186888.1 2137443 R 93062 CDS YP_186889.1 57650755 3238042 complement(2139480..2140838) 1 NC_002951.2 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM TIGR01143; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 2140838 murF 3238042 murF Staphylococcus aureus subsp. aureus COL UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_186889.1 2139480 R 93062 CDS YP_186890.1 57650756 3238133 complement(2140853..2141923) 1 NC_002951.2 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 2141923 ddl 3238133 ddl Staphylococcus aureus subsp. aureus COL D-alanyl-alanine synthetase A YP_186890.1 2140853 R 93062 CDS YP_186891.1 57650757 3238134 2142241..2143443 1 NC_002951.2 identified by match to protein family HMM PF01098; cell cycle protein FtsW 2143443 ftsW 3238134 ftsW Staphylococcus aureus subsp. aureus COL cell cycle protein FtsW YP_186891.1 2142241 D 93062 CDS YP_186892.1 57650758 3238493 complement(2143707..2143844) 1 NC_002951.2 identified by similarity to GB:AAO05283.1; hypothetical protein 2143844 3238493 SACOL2076 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186892.1 2143707 R 93062 CDS YP_186893.1 57650759 3238494 complement(2143972..2144181) 1 NC_002951.2 identified by similarity to GB:AAO05284.1; match to protein family HMM PF00403; hypothetical protein 2144181 3238494 SACOL2077 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186893.1 2143972 R 93062 CDS YP_186894.1 57650760 3238400 complement(2144193..2144486) 1 NC_002951.2 identified by match to protein family HMM PF02583; hypothetical protein 2144486 3238400 SACOL2078 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186894.1 2144193 R 93062 CDS YP_186895.1 57650761 3238401 2144652..2146136 1 NC_002951.2 identified by similarity to SP:O66043; match to protein family HMM PF00614; cardiolipin synthetase 2146136 cls2 3238401 cls2 Staphylococcus aureus subsp. aureus COL cardiolipin synthetase YP_186895.1 2144652 D 93062 CDS YP_186896.1 57650762 3238511 2146164..2146811 1 NC_002951.2 identified by similarity to GP:10175456; match to protein family HMM PF01966; HD domain-containing protein 2146811 3238511 SACOL2080 Staphylococcus aureus subsp. aureus COL HD domain-containing protein YP_186896.1 2146164 D 93062 CDS YP_186897.1 57650763 3238512 complement(2146986..2147078) 1 NC_002951.2 hypothetical protein 2147078 3238512 SACOL2081 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186897.1 2146986 R 93062 CDS YP_186898.1 57650764 3238110 complement(2147624..2148496) 1 NC_002951.2 identified by match to protein family HMM PF02096; hypothetical protein 2148496 3238110 SACOL2082 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186898.1 2147624 R 93062 CDS YP_186899.1 57650765 3238111 complement(2148582..2149223) 1 NC_002951.2 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 2149223 thiE 3238111 thiE Staphylococcus aureus subsp. aureus COL thiamine-phosphate pyrophosphorylase YP_186899.1 2148582 R 93062 CDS YP_186900.1 57650766 3238160 complement(2149225..2150016) 1 NC_002951.2 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 2150016 thiM 3238160 thiM Staphylococcus aureus subsp. aureus COL hydroxyethylthiazole kinase YP_186900.1 2149225 R 93062 CDS YP_186901.1 57650767 3238664 complement(2150000..2150830) 1 NC_002951.2 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 2150830 thiD2 3238664 thiD2 Staphylococcus aureus subsp. aureus COL phosphomethylpyrimidine kinase YP_186901.1 2150000 R 93062 CDS YP_186902.1 57650768 3238665 complement(2150823..2151512) 1 NC_002951.2 identified by similarity to EGAD:24145; match to protein family HMM PF03070; TenA family transcription regulator 2151512 3238665 SACOL2086 Staphylococcus aureus subsp. aureus COL TenA family transcription regulator YP_186902.1 2150823 R 93062 CDS YP_186903.1 57650769 3238684 complement(2151898..2152593) 1 NC_002951.2 identified by match to protein family HMM PF06737; sceD protein 2152593 3238684 SACOL2088 Staphylococcus aureus subsp. aureus COL sceD protein YP_186903.1 2151898 R 93062 CDS YP_186904.1 57650770 3238685 complement(2152982..2153377) 1 NC_002951.2 identified by similarity to EGAD:17778; match to protein family HMM PF00436; match to protein family HMM TIGR00621; ssDNA-binding protein 2153377 3238685 SACOL2089 Staphylococcus aureus subsp. aureus COL ssDNA-binding protein YP_186904.1 2152982 R 93062 CDS YP_186905.1 57650771 3238675 2153571..2154011 1 NC_002951.2 identified by similarity to GP:2735511; hypothetical protein 2154011 ywpF 3238675 ywpF Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186905.1 2153571 D 93062 CDS YP_186906.1 57650772 3238676 complement(2154070..2154510) 1 NC_002951.2 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 2154510 fabZ 3238676 fabZ Staphylococcus aureus subsp. aureus COL (3R)-hydroxymyristoyl-ACP dehydratase YP_186906.1 2154070 R 93062 CDS YP_186907.1 57650773 3238693 complement(2154544..2155809) 1 NC_002951.2 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2155809 murAA 3238693 murAA Staphylococcus aureus subsp. aureus COL UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_186907.1 2154544 R 93062 CDS YP_186908.1 57650774 3238694 complement(2155920..2156153) 1 NC_002951.2 identified by match to protein family HMM PF06612; match to protein family HMM TIGR02327; hypothetical protein 2156153 3238694 SACOL2093 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186908.1 2155920 R 93062 CDS YP_186909.1 57652124 3237489 complement(2156715..2157119) 1 NC_002951.2 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 2157119 atpC 3237489 atpC Staphylococcus aureus subsp. aureus COL F0F1 ATP synthase subunit epsilon YP_186909.1 2156715 R 93062 CDS YP_186910.1 57652125 3237490 complement(2157139..2158551) 1 NC_002951.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 2158551 atpD 3237490 atpD Staphylococcus aureus subsp. aureus COL F0F1 ATP synthase subunit beta YP_186910.1 2157139 R 93062 CDS YP_186911.1 57652126 3237491 complement(2158573..2159439) 1 NC_002951.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 2159439 atpG 3237491 atpG Staphylococcus aureus subsp. aureus COL F0F1 ATP synthase subunit gamma YP_186911.1 2158573 R 93062 CDS YP_186912.1 57652127 3237492 complement(2159470..2160978) 1 NC_002951.2 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 2160978 atpA 3237492 atpA Staphylococcus aureus subsp. aureus COL F0F1 ATP synthase subunit alpha YP_186912.1 2159470 R 93062 CDS YP_186913.1 57652128 3237493 complement(2161000..2161539) 1 NC_002951.2 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 2161539 atpH 3237493 atpH Staphylococcus aureus subsp. aureus COL F0F1 ATP synthase subunit delta YP_186913.1 2161000 R 93062 CDS YP_186914.1 57652129 3237494 complement(2161539..2162060) 1 NC_002951.2 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit B is part of the membrane proton channel; F0F1 ATP synthase subunit B 2162060 atpF 3237494 atpF Staphylococcus aureus subsp. aureus COL F0F1 ATP synthase subunit B YP_186914.1 2161539 R 93062 CDS YP_186915.1 57652130 3237481 complement(2162258..2162470) 1 NC_002951.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 2162470 atpE 3237481 atpE Staphylococcus aureus subsp. aureus COL F0F1 ATP synthase subunit C YP_186915.1 2162258 R 93062 CDS YP_186916.1 57652131 3237482 complement(2162513..2163241) 1 NC_002951.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 2163241 atpB 3237482 atpB Staphylococcus aureus subsp. aureus COL F0F1 ATP synthase subunit A YP_186916.1 2162513 R 93062 CDS YP_186917.1 57652132 3237483 complement(2163262..2163615) 1 NC_002951.2 identified by similarity to GB:AAO05306.1; hypothetical protein 2163615 3237483 SACOL2102 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186917.1 2163262 R 93062 CDS YP_186918.1 57652133 3237484 complement(2163782..2164909) 1 NC_002951.2 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236; UDP-GlcNAc 2-epimerase 2164909 3237484 SACOL2103 Staphylococcus aureus subsp. aureus COL UDP-GlcNAc 2-epimerase YP_186918.1 2163782 R 93062 CDS YP_186919.1 57652134 3237485 complement(2164933..2165562) 1 NC_002951.2 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 2165562 upp 3237485 upp Staphylococcus aureus subsp. aureus COL uracil phosphoribosyltransferase YP_186919.1 2164933 R 93062 CDS YP_186920.1 57652135 3237486 complement(2165590..2166828) 1 NC_002951.2 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 2166828 glyA 3237486 glyA Staphylococcus aureus subsp. aureus COL serine hydroxymethyltransferase YP_186920.1 2165590 R 93062 CDS YP_186921.1 57652136 3237487 complement(2166855..2167379) 1 NC_002951.2 identified by match to protein family HMM PF04260; match to protein family HMM TIGR01440; hypothetical protein 2167379 3237487 SACOL2106 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186921.1 2166855 R 93062 CDS YP_186922.1 57652137 3237473 complement(2167486..2167905) 1 NC_002951.2 identified by similarity to EGAD:30369; match to protein family HMM PF01451; phosphotyrosine protein phosphatase 2167905 3237473 SACOL2107 Staphylococcus aureus subsp. aureus COL phosphotyrosine protein phosphatase YP_186922.1 2167486 R 93062 CDS YP_186923.1 57652138 3237474 complement(2167902..2168957) 1 NC_002951.2 identified by match to protein family HMM PF01300; match to protein family HMM PF03481; match to protein family HMM TIGR00057; Sua5/YciO/YrdC/YwlC family protein 2168957 3237474 SACOL2108 Staphylococcus aureus subsp. aureus COL Sua5/YciO/YrdC/YwlC family protein YP_186923.1 2167902 R 93062 CDS YP_186924.1 57652139 3237475 complement(2169032..2169868) 1 NC_002951.2 identified by match to protein family HMM TIGR00536; HemK family modification methylase 2169868 3237475 SACOL2109 Staphylococcus aureus subsp. aureus COL HemK family modification methylase YP_186924.1 2169032 R 93062 CDS YP_186925.1 57652140 3237476 complement(2169855..2170931) 1 NC_002951.2 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 2170931 prfA 3237476 prfA Staphylococcus aureus subsp. aureus COL peptide chain release factor 1 YP_186925.1 2169855 R 93062 CDS YP_186926.1 57652141 3237477 complement(2170932..2171531) 1 NC_002951.2 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 2171531 tdk 3237477 tdk Staphylococcus aureus subsp. aureus COL thymidine kinase YP_186926.1 2170932 R 93062 CDS YP_186927.1 57652142 3237478 complement(2171878..2172132) 1 NC_002951.2 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 2172132 rpmE2 3237478 rpmE2 Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L31 YP_186927.1 2171878 R 93062 CDS YP_186928.1 57652143 3237479 complement(2172250..2173566) 1 NC_002951.2 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 2173566 rho 3237479 rho Staphylococcus aureus subsp. aureus COL transcription termination factor Rho YP_186928.1 2172250 R 93062 CDS YP_186929.1 57652144 3237480 complement(2173813..2175240) 1 NC_002951.2 identified by match to protein family HMM PF00171; aldehyde dehydrogenase 2175240 3237480 SACOL2114 Staphylococcus aureus subsp. aureus COL aldehyde dehydrogenase YP_186929.1 2173813 R 93062 CDS YP_186930.1 57652145 3237466 complement(2175478..2175813) 1 NC_002951.2 identified by similarity to EGAD:109282; match to protein family HMM PF01638; hypothetical protein 2175813 3237466 SACOL2115 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186930.1 2175478 R 93062 CDS YP_186931.1 57652146 3237467 complement(2175902..2177161) 1 NC_002951.2 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2177161 murAB 3237467 murAB Staphylococcus aureus subsp. aureus COL UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_186931.1 2175902 R 93062 CDS YP_186932.1 57652147 3237468 complement(2177627..2178487) 1 NC_002951.2 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; induced by anaerobic conditions in Bacillus subtilis; fructose-bisphosphate aldolase 2178487 fbaA 3237468 fbaA Staphylococcus aureus subsp. aureus COL fructose-bisphosphate aldolase YP_186932.1 2177627 R 93062 CDS YP_186933.1 57652148 3237469 2178705..2179226 1 NC_002951.2 hypothetical protein 2179226 3237469 SACOL2118 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186933.1 2178705 D 93062 CDS YP_186934.1 57652149 3237470 complement(2179335..2180945) 1 NC_002951.2 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 2180945 pyrG 3237470 pyrG Staphylococcus aureus subsp. aureus COL CTP synthetase YP_186934.1 2179335 R 93062 CDS YP_186935.1 57652150 3237471 complement(2181281..2181811) 1 NC_002951.2 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 2181811 rpoE 3237471 rpoE Staphylococcus aureus subsp. aureus COL DNA-directed RNA polymerase subunit delta YP_186935.1 2181281 R 93062 CDS YP_186936.1 57652151 3237472 complement(2181923..2182783) 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 2182783 3237472 SACOL2121 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_186936.1 2181923 R 93062 CDS YP_186937.1 57652152 3237458 2183207..2184010 1 NC_002951.2 catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type II pantothenate kinases are not regulated by feedback inhibition by coenzyme A; pantothenate kinase 2184010 3237458 SACOL2122 Staphylococcus aureus subsp. aureus COL pantothenate kinase YP_186937.1 2183207 D 93062 CDS YP_186938.1 57652153 3237459 complement(2184140..2184811) 1 NC_002951.2 identified by similarity to GB:AAO05328.1; hypothetical protein 2184811 3237459 SACOL2123 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186938.1 2184140 R 93062 CDS YP_186939.1 57652154 3237460 complement(2185210..2186403) 1 NC_002951.2 identified by similarity to GB:AAO05329.1; hypothetical protein 2186403 3237460 SACOL2124 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186939.1 2185210 R 93062 CDS YP_186940.1 57652155 3237461 complement(2186403..2187587) 1 NC_002951.2 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; M20/M25/M40 family peptidase 2187587 3237461 SACOL2125 Staphylococcus aureus subsp. aureus COL M20/M25/M40 family peptidase YP_186940.1 2186403 R 93062 CDS YP_186941.1 57652156 3237462 2187898..2188368 1 NC_002951.2 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 2188368 luxS 3237462 luxS Staphylococcus aureus subsp. aureus COL S-ribosylhomocysteinase YP_186941.1 2187898 D 93062 CDS YP_186942.1 57652157 3237463 complement(2188520..2188870) 1 NC_002951.2 hypothetical protein 2188870 3237463 SACOL2127 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186942.1 2188520 R 93062 CDS YP_186943.1 57652158 3237464 complement(2188884..2190185) 1 NC_002951.2 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase 2190185 pdp 3237464 pdp Staphylococcus aureus subsp. aureus COL pyrimidine-nucleoside phosphorylase YP_186943.1 2188884 R 93062 CDS YP_186944.1 57652159 3237449 complement(2190464..2191126) 1 NC_002951.2 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 2191126 deoC2 3237449 deoC2 Staphylococcus aureus subsp. aureus COL deoxyribose-phosphate aldolase YP_186944.1 2190464 R 93062 CDS YP_186945.1 57652160 3237450 2191441..2192151 1 NC_002951.2 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 2192151 deoD 3237450 deoD Staphylococcus aureus subsp. aureus COL purine nucleoside phosphorylase YP_186945.1 2191441 D 93062 CDS YP_186946.1 57652161 3237451 complement(2192272..2192715) 1 NC_002951.2 identified by match to protein family HMM PF00210; Dps family protein 2192715 3237451 SACOL2131 Staphylococcus aureus subsp. aureus COL Dps family protein YP_186946.1 2192272 R 93062 CDS YP_186947.1 57652162 3237452 complement(2192915..2193328) 1 NC_002951.2 identified by similarity to GP:10173467; match to protein family HMM PF04134; hypothetical protein 2193328 3237452 SACOL2132 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186947.1 2192915 R 93062 CDS YP_186948.1 57652163 3237453 complement(2193786..2195159) 1 NC_002951.2 identified by similarity to GB:AAO05339.1; hypothetical protein 2195159 3237453 SACOL2133 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186948.1 2193786 R 93062 CDS YP_186949.1 57652164 3237454 complement(2195831..2196061) 1 NC_002951.2 identified by similarity to GB:AAO05341.1; hypothetical protein 2196061 3237454 SACOL2134 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186949.1 2195831 R 93062 CDS YP_186950.1 57652165 3237455 complement(2196092..2197030) 1 NC_002951.2 identified by similarity to EGAD:14340; match to protein family HMM PF01238; match to protein family HMM TIGR00218; mannose-6-phosphate isomerase, class I 2197030 manA1 3237455 manA1 Staphylococcus aureus subsp. aureus COL mannose-6-phosphate isomerase, class I YP_186950.1 2196092 R 93062 CDS YP_186951.1 57652166 3237442 complement(2197465..2198130) 1 NC_002951.2 hypothetical protein 2198130 3237442 SACOL2136 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186951.1 2197465 R 93062 CDS YP_186952.1 57652167 3237443 2198282..2198602 1 NC_002951.2 identified by similarity to GP:4126673; similarity to OMNI:SA2137; match to protein family HMM PF01022; transcriptional regulator CzrA 2198602 czrA 3237443 czrA Staphylococcus aureus subsp. aureus COL transcriptional regulator CzrA YP_186952.1 2198282 D 93062 CDS YP_186953.1 57652168 3237444 2198604..2199584 1 NC_002951.2 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux family protein 2199584 3237444 SACOL2138 Staphylococcus aureus subsp. aureus COL cation efflux family protein YP_186953.1 2198604 D 93062 CDS YP_186954.1 57652169 3237445 2199794..2199901 1 NC_002951.2 hypothetical protein 2199901 3237445 SACOL2139 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186954.1 2199794 D 93062 CDS YP_186955.1 57652170 3237448 complement(2202166..2203302) 1 NC_002951.2 SAP domain-containing protein 2203302 3237448 SACOL2142 Staphylococcus aureus subsp. aureus COL SAP domain-containing protein YP_186955.1 2202166 R 93062 CDS YP_186956.1 57652171 3237435 complement(2204388..2205257) 1 NC_002951.2 identified by similarity to GP:10174364; match to protein family HMM PF00702; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; hypothetical protein 2205257 3237435 SACOL2143 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186956.1 2204388 R 93062 CDS YP_186957.1 57652172 3237436 complement(2205313..2206095) 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2206095 3237436 SACOL2144 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_186957.1 2205313 R 93062 CDS YP_186958.1 57652173 3237437 complement(2206327..2208132) 1 NC_002951.2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 2208132 glmS 3237437 glmS Staphylococcus aureus subsp. aureus COL glucosamine--fructose-6-phosphate aminotransferase YP_186958.1 2206327 R 93062 CDS YP_186959.1 57652174 3237438 2208813..2210351 1 NC_002951.2 identified by match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851; PTS system, mannitol-specific IIBC components 2210351 3237438 SACOL2146 Staphylococcus aureus subsp. aureus COL PTS system, mannitol-specific IIBC components YP_186959.1 2208813 D 93062 CDS YP_186960.1 57652175 3237439 2210386..2212518 1 NC_002951.2 identified by match to protein family HMM PF00874; BglG family transcriptional antiterminator 2212518 3237439 SACOL2147 Staphylococcus aureus subsp. aureus COL BglG family transcriptional antiterminator YP_186960.1 2210386 D 93062 CDS YP_186961.1 57652176 3237440 2212530..2212964 1 NC_002951.2 identified by similarity to SP:P17875; match to protein family HMM PF00359; PTS system, mannitol-specific IIA component 2212964 3237440 SACOL2148 Staphylococcus aureus subsp. aureus COL PTS system, mannitol-specific IIA component YP_186961.1 2212530 D 93062 CDS YP_186962.1 57652177 3237441 2212964..2214070 1 NC_002951.2 identified by similarity to EGAD:16282; match to protein family HMM PF01232; mannitol-1-phosphate 5-dehydrogenase 2214070 mtlD 3237441 mtlD Staphylococcus aureus subsp. aureus COL mannitol-1-phosphate 5-dehydrogenase YP_186962.1 2212964 D 93062 CDS YP_186963.1 57652178 3237427 complement(2214389..2221825) 1 NC_002951.2 identified by similarity to GP:5834649; match to protein family HMM PF04650; match to protein family HMM PF07564; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; fmtB protiein 2221825 fmtB 3237427 fmtB Staphylococcus aureus subsp. aureus COL fmtB protiein YP_186963.1 2214389 R 93062 CDS YP_186964.1 57652179 3237428 complement(2222102..2223457) 1 NC_002951.2 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 2223457 glmM 3237428 glmM Staphylococcus aureus subsp. aureus COL phosphoglucosamine mutase YP_186964.1 2222102 R 93062 CDS YP_186965.1 57652180 3237429 complement(2223484..2224416) 1 NC_002951.2 hypothetical protein 2224416 3237429 SACOL2152 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186965.1 2223484 R 93062 CDS YP_186966.1 57652181 3237430 complement(2224418..2225227) 1 NC_002951.2 identified by similarity to EGAD:108364; match to protein family HMM PF02457; match to protein family HMM TIGR00159; hypothetical protein 2225227 3237430 SACOL2153 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186966.1 2224418 R 93062 CDS YP_186967.1 57652182 3237431 complement(2225416..2226324) 1 NC_002951.2 identified by similarity to EGAD:14086; match to protein family HMM PF00491; match to protein family HMM TIGR01229; arginase 2226324 rocF 3237431 rocF Staphylococcus aureus subsp. aureus COL arginase YP_186967.1 2225416 R 93062 CDS YP_186968.1 57652183 3237433 complement(2234163..2235227) 1 NC_002951.2 ATP-binding Mrp/Nbp35 family protein 2235227 3237433 SACOL2156 Staphylococcus aureus subsp. aureus COL ATP-binding Mrp/Nbp35 family protein YP_186968.1 2234163 R 93062 CDS YP_186969.1 57652184 3237419 complement(2235375..2236817) 1 NC_002951.2 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; EmrB/QacA family drug resistance transporter 2236817 3237419 SACOL2157 Staphylococcus aureus subsp. aureus COL EmrB/QacA family drug resistance transporter YP_186969.1 2235375 R 93062 CDS YP_186970.1 57652185 3237420 complement(2237139..2237612) 1 NC_002951.2 identified by similarity to GB:AAO05399.1; hypothetical protein 2237612 3237420 SACOL2158 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186970.1 2237139 R 93062 CDS YP_186971.1 57652186 3237421 complement(2237711..2239054) 1 NC_002951.2 identified by match to protein family HMM PF07690; drug transporter 2239054 3237421 SACOL2159 Staphylococcus aureus subsp. aureus COL drug transporter YP_186971.1 2237711 R 93062 CDS YP_186972.1 57652187 3237422 complement(2239231..2239914) 1 NC_002951.2 identified by similarity to EGAD:38000; match to protein family HMM PF03006; match to protein family HMM TIGR01065; hemolysin III 2239914 3237422 SACOL2160 Staphylococcus aureus subsp. aureus COL hemolysin III YP_186972.1 2239231 R 93062 CDS YP_186973.1 57652188 3237423 complement(2239933..2241120) 1 NC_002951.2 identified by match to protein family HMM PF01704; UTP-glucose-1-phosphate uridylyltransferase 2241120 3237423 SACOL2161 Staphylococcus aureus subsp. aureus COL UTP-glucose-1-phosphate uridylyltransferase YP_186973.1 2239933 R 93062 CDS YP_186974.1 57652189 3237424 complement(2241164..2241679) 1 NC_002951.2 identified by match to protein family HMM PF04307; hypothetical protein 2241679 3237424 SACOL2162 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186974.1 2241164 R 93062 CDS YP_186975.1 57652190 3237425 2241857..2242117 1 NC_002951.2 hypothetical protein 2242117 3237425 SACOL2163 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186975.1 2241857 D 93062 CDS YP_186976.1 57652191 3237426 complement(2242249..2243619) 1 NC_002951.2 identified by similarity to GP:10176572; match to protein family HMM PF07670; hypothetical protein 2243619 3237426 SACOL2164 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186976.1 2242249 R 93062 CDS YP_186977.1 57652192 3237412 complement(2243855..2244823) 1 NC_002951.2 identified by similarity to EGAD:7245; match to protein family HMM PF01032; iron compound ABC transporter permease 2244823 3237412 SACOL2165 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter permease YP_186977.1 2243855 R 93062 CDS YP_186978.1 57652193 3237413 complement(2244820..2245851) 1 NC_002951.2 identified by similarity to EGAD:23253; match to protein family HMM PF01032; iron compound ABC transporter permease 2245851 3237413 SACOL2166 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter permease YP_186978.1 2244820 R 93062 CDS YP_186979.1 57652194 3237414 complement(2245863..2246846) 1 NC_002951.2 identified by match to protein family HMM PF01497; iron compound ABC transporter iron compound-binding protein 2246846 3237414 SACOL2167 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter iron compound-binding protein YP_186979.1 2245863 R 93062 CDS YP_186980.1 57652195 3237415 complement(2247238..2248308) 1 NC_002951.2 identified by match to protein family HMM PF01168; hypothetical protein 2248308 3237415 SACOL2168 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186980.1 2247238 R 93062 CDS YP_186981.1 57652196 3237416 complement(2248315..2250072) 1 NC_002951.2 identified by match to protein family HMM PF04183; aerobactin biosynthesis protein 2250072 3237416 SACOL2169 Staphylococcus aureus subsp. aureus COL aerobactin biosynthesis protein YP_186981.1 2248315 R 93062 CDS YP_186982.1 57652197 3237417 complement(2250059..2251252) 1 NC_002951.2 identified by match to protein family HMM PF05977; match to protein family HMM PF07690; transporter 2251252 3237417 SACOL2170 Staphylococcus aureus subsp. aureus COL transporter YP_186982.1 2250059 R 93062 CDS YP_186983.1 57652198 3237418 2251354..2253330 1 NC_002951.2 identified by match to protein family HMM PF04183; aerobactin biosynthesis protein 2253330 3237418 SACOL2171 Staphylococcus aureus subsp. aureus COL aerobactin biosynthesis protein YP_186983.1 2251354 D 93062 CDS YP_186984.1 57652199 3237405 complement(2255446..2255955) 1 NC_002951.2 identified by similarity to EGAD:40949; match to protein family HMM PF03780; alkaline shock protein 23 2255955 3237405 SACOL2173 Staphylococcus aureus subsp. aureus COL alkaline shock protein 23 YP_186984.1 2255446 R 93062 CDS YP_186985.1 57652200 3237406 complement(2256018..2256257) 1 NC_002951.2 identified by similarity to GB:AAO05416.1; hypothetical protein 2256257 3237406 SACOL2174 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186985.1 2256018 R 93062 CDS YP_186986.1 57652201 3237407 complement(2256270..2256818) 1 NC_002951.2 identified by similarity to GB:AAO05417.1; hypothetical protein 2256818 3237407 SACOL2175 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186986.1 2256270 R 93062 CDS YP_186987.1 57652202 3237408 complement(2256981..2258543) 1 NC_002951.2 identified by similarity to EGAD:45763; match to protein family HMM PF02028; match to protein family HMM TIGR00842; BCCT family osmoprotectant transporter 2258543 opuD2 3237408 opuD2 Staphylococcus aureus subsp. aureus COL BCCT family osmoprotectant transporter YP_186987.1 2256981 R 93062 CDS YP_186988.1 57652203 3237409 complement(2258850..2259851) 1 NC_002951.2 identified by match to protein family HMM PF00107; alcohol dehydrogenase, zinc-containing 2259851 3237409 SACOL2177 Staphylococcus aureus subsp. aureus COL alcohol dehydrogenase, zinc-containing YP_186988.1 2258850 R 93062 CDS YP_186989.1 57652204 3237410 complement(2260085..2261086) 1 NC_002951.2 identified by match to protein family HMM PF00107; alcohol dehydrogenase, zinc-containing 2261086 3237410 SACOL2178 Staphylococcus aureus subsp. aureus COL alcohol dehydrogenase, zinc-containing YP_186989.1 2260085 R 93062 CDS YP_186990.1 57650775 3238416 complement(2261369..2262238) 1 NC_002951.2 identified by match to protein family HMM PF06028; hypothetical protein 2262238 3238416 SACOL2179 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186990.1 2261369 R 93062 CDS YP_186991.1 57650776 3238417 complement(2262504..2263916) 1 NC_002951.2 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; 6-phospho-beta-galactosidase 2263916 lacG 3238417 lacG Staphylococcus aureus subsp. aureus COL 6-phospho-beta-galactosidase YP_186991.1 2262504 R 93062 CDS YP_186992.1 57650777 3238567 complement(2263934..2265652) 1 NC_002951.2 identified by similarity to EGAD:22339; match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00394; match to protein family HMM TIGR00410; match to protein family HMM TIGR00853; PTS system, lactose-specific IIBC components 2265652 lacE 3238567 lacE Staphylococcus aureus subsp. aureus COL PTS system, lactose-specific IIBC components YP_186992.1 2263934 R 93062 CDS YP_186993.1 57650778 3238568 complement(2265652..2265963) 1 NC_002951.2 identified by similarity to EGAD:18801; match to protein family HMM PF02255; match to protein family HMM TIGR00823; PTS system, lactose-specific IIA component 2265963 lacF 3238568 lacF Staphylococcus aureus subsp. aureus COL PTS system, lactose-specific IIA component YP_186993.1 2265652 R 93062 CDS YP_186994.1 57650779 3238060 complement(2265985..2266965) 1 NC_002951.2 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 2266965 lacD 3238060 lacD Staphylococcus aureus subsp. aureus COL tagatose 1,6-diphosphate aldolase YP_186994.1 2265985 R 93062 CDS YP_186995.1 57650780 3238197 complement(2266969..2267901) 1 NC_002951.2 catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP; tagatose-6-phosphate kinase 2267901 lacC 3238197 lacC Staphylococcus aureus subsp. aureus COL tagatose-6-phosphate kinase YP_186995.1 2266969 R 93062 CDS YP_186996.1 57650781 3238198 complement(2267914..2268429) 1 NC_002951.2 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; galactose-6-phosphate isomerase subunit LacB 2268429 lacB 3238198 lacB Staphylococcus aureus subsp. aureus COL galactose-6-phosphate isomerase subunit LacB YP_186996.1 2267914 R 93062 CDS YP_186997.1 57650782 3238604 complement(2268445..2268873) 1 NC_002951.2 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization; galactose-6-phosphate isomerase subunit LacA 2268873 3238604 SACOL2186 Staphylococcus aureus subsp. aureus COL galactose-6-phosphate isomerase subunit LacA YP_186997.1 2268445 R 93062 CDS YP_186998.1 57650783 3238605 complement(2268888..2269004) 1 NC_002951.2 hypothetical protein 2269004 3238605 SACOL2187 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_186998.1 2268888 R 93062 CDS YP_186999.1 57650784 3238563 complement(2269241..2269996) 1 NC_002951.2 identified by similarity to SP:P16644; match to protein family HMM PF00455; lactose phosphotransferase system repressor 2269996 lacR 3238563 lacR Staphylococcus aureus subsp. aureus COL lactose phosphotransferase system repressor YP_186999.1 2269241 R 93062 CDS YP_187000.1 57650785 3238564 2270247..2270978 1 NC_002951.2 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 2270978 3238564 SACOL2189 Staphylococcus aureus subsp. aureus COL NAD-dependent deacetylase YP_187000.1 2270247 D 93062 CDS YP_187001.1 57650786 3238090 complement(2271269..2271877) 1 NC_002951.2 hypothetical protein 2271877 3238090 SACOL2190 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187001.1 2271269 R 93062 CDS YP_187002.1 57650787 3238091 complement(2272139..2272264) 1 NC_002951.2 hypothetical protein 2272264 3238091 SACOL2191 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187002.1 2272139 R 93062 CDS YP_187003.1 57650788 3238569 complement(2272484..2273332) 1 NC_002951.2 identified by match to protein family HMM PF00248; aldo/keto reductase oxidoreductase 2273332 3238569 SACOL2192 Staphylococcus aureus subsp. aureus COL aldo/keto reductase oxidoreductase YP_187003.1 2272484 R 93062 CDS YP_187004.1 57650789 3238570 complement(2273402..2273818) 1 NC_002951.2 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 2273818 3238570 SACOL2193 Staphylococcus aureus subsp. aureus COL MerR family transcriptional regulator YP_187004.1 2273402 R 93062 CDS YP_187005.1 57650790 3238658 2274226..2276649 1 NC_002951.2 identified by similarity to EGAD:42558; match to protein family HMM PF02278; match to protein family HMM PF02884; hyaluronate lyase 2276649 hysA 3238658 hysA Staphylococcus aureus subsp. aureus COL hyaluronate lyase YP_187005.1 2274226 D 93062 CDS YP_187006.1 57650791 3238659 complement(2276709..2277563) 1 NC_002951.2 identified by match to protein family HMM PF01551; M23/M37 peptidase domain-containing protein 2277563 3238659 SACOL2195 Staphylococcus aureus subsp. aureus COL M23/M37 peptidase domain-containing protein YP_187006.1 2276709 R 93062 CDS YP_187007.1 57650792 3238068 complement(2277774..2278589) 1 NC_002951.2 identified by match to protein family HMM TIGR01484; hypothetical protein 2278589 3238068 SACOL2196 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187007.1 2277774 R 93062 CDS YP_187008.1 57650793 3238069 2278883..2279308 1 NC_002951.2 identified by match to protein family HMM PF03642; surface protein 2279308 3238069 SACOL2197 Staphylococcus aureus subsp. aureus COL surface protein YP_187008.1 2278883 D 93062 CDS YP_187009.1 57650794 3238531 complement(2279672..2280376) 1 NC_002951.2 identified by similarity to EGAD:17067; match to protein family HMM PF03306; match to protein family HMM TIGR01252; alpha-acetolactate decarboxylase 2280376 budA1 3238531 budA1 Staphylococcus aureus subsp. aureus COL alpha-acetolactate decarboxylase YP_187009.1 2279672 R 93062 CDS YP_187010.1 57650795 3238195 complement(2280413..2282077) 1 NC_002951.2 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase; acetolactate synthase 2282077 budB 3238195 budB Staphylococcus aureus subsp. aureus COL acetolactate synthase YP_187010.1 2280413 R 93062 CDS YP_187011.1 57650796 3238196 2282357..2282452 1 NC_002951.2 hypothetical protein 2282452 3238196 SACOL2200 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187011.1 2282357 D 93062 CDS YP_187012.1 57650797 3238496 complement(2283267..2283866) 1 NC_002951.2 hypothetical protein 2283866 3238496 SACOL2201 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187012.1 2283267 R 93062 CDS YP_187013.1 57650798 3238497 complement(2283899..2284672) 1 NC_002951.2 hypothetical protein 2284672 3238497 SACOL2202 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187013.1 2283899 R 93062 CDS YP_187014.1 57650799 3238479 complement(2284801..2285937) 1 NC_002951.2 ClpA-like protein 2285937 3238479 SACOL2203 Staphylococcus aureus subsp. aureus COL ClpA-like protein YP_187014.1 2284801 R 93062 CDS YP_187015.1 57650800 3238480 complement(2285938..2286729) 1 NC_002951.2 hypothetical protein 2286729 3238480 SACOL2204 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187015.1 2285938 R 93062 CDS YP_187016.1 57650801 3237881 complement(2288674..2289072) 1 NC_002951.2 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 2289072 rpsI 3237881 rpsI Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S9 YP_187016.1 2288674 R 93062 CDS YP_187017.1 57650802 3237137 complement(2289086..2289523) 1 NC_002951.2 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 2289523 rplM 3237137 rplM Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L13 YP_187017.1 2289086 R 93062 CDS YP_187018.1 57650803 3237138 complement(2289763..2290566) 1 NC_002951.2 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 2290566 truA 3237138 truA Staphylococcus aureus subsp. aureus COL tRNA pseudouridine synthase A YP_187018.1 2289763 R 93062 CDS YP_187019.1 57650804 3238696 complement(2290571..2291377) 1 NC_002951.2 identified by match to protein family HMM PF02361; cobalt transport family protein 2291377 3238696 SACOL2209 Staphylococcus aureus subsp. aureus COL cobalt transport family protein YP_187019.1 2290571 R 93062 CDS YP_187020.1 57650805 3238666 complement(2291367..2292227) 1 NC_002951.2 with CbiNQ forms the ABC transporter for cobalt import; Staphylococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2292227 cbiO 3238666 cbiO Staphylococcus aureus subsp. aureus COL cobalt transporter ATP-binding subunit YP_187020.1 2291367 R 93062 CDS YP_187021.1 57650806 3238667 complement(2292224..2293033) 1 NC_002951.2 with CbiNQ forms the ABC transporter for cobalt import; Staphylococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2293033 cbiO 3238667 cbiO Staphylococcus aureus subsp. aureus COL cobalt transporter ATP-binding subunit YP_187021.1 2292224 R 93062 CDS YP_187022.1 57650807 3238613 complement(2293571..2293939) 1 NC_002951.2 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 2293939 rplQ 3238613 rplQ Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L17 YP_187022.1 2293571 R 93062 CDS YP_187023.1 57650808 3238614 complement(2293956..2294900) 1 NC_002951.2 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 2294900 rpoA 3238614 rpoA Staphylococcus aureus subsp. aureus COL DNA-directed RNA polymerase subunit alpha YP_187023.1 2293956 R 93062 CDS YP_187024.1 57650809 3238374 complement(2294975..2295364) 1 NC_002951.2 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 2295364 rpsK 3238374 rpsK Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S11 YP_187024.1 2294975 R 93062 CDS YP_187025.1 57650810 3238375 complement(2295388..2295753) 1 NC_002951.2 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 2295753 rpsM 3238375 rpsM Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S13 YP_187025.1 2295388 R 93062 CDS YP_187026.1 57650811 3237566 complement(2295776..2295889) 1 NC_002951.2 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 2295889 rpmJ 3237566 rpmJ Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L36 YP_187026.1 2295776 R 93062 CDS YP_187027.1 57650812 3237567 complement(2295921..2296139) 1 NC_002951.2 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 2296139 infA 3237567 infA Staphylococcus aureus subsp. aureus COL translation initiation factor IF-1 YP_187027.1 2295921 R 93062 CDS YP_187028.1 57650813 3237692 complement(2296332..2296979) 1 NC_002951.2 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 2296979 adk 3237692 adk Staphylococcus aureus subsp. aureus COL adenylate kinase YP_187028.1 2296332 R 93062 CDS YP_187029.1 57650814 3237693 complement(2296996..2298288) 1 NC_002951.2 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 2298288 secY 3237693 secY Staphylococcus aureus subsp. aureus COL preprotein translocase subunit SecY YP_187029.1 2296996 R 93062 CDS YP_187030.1 57650815 3238662 complement(2298288..2298728) 1 NC_002951.2 late assembly protein; 50S ribosomal protein L15 2298728 rplO 3238662 rplO Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L15 YP_187030.1 2298288 R 93062 CDS YP_187031.1 57650816 3238663 complement(2298745..2298924) 1 NC_002951.2 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 2298924 rpmD 3238663 rpmD Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L30 YP_187031.1 2298745 R 93062 CDS YP_187032.1 57650817 3238048 complement(2298941..2299441) 1 NC_002951.2 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 2299441 rpsE 3238048 rpsE Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S5 YP_187032.1 2298941 R 93062 CDS YP_187033.1 57650818 3238049 complement(2299462..2299821) 1 NC_002951.2 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 2299821 rplR 3238049 rplR Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L18 YP_187033.1 2299462 R 93062 CDS YP_187034.1 57650819 3238328 complement(2299852..2300388) 1 NC_002951.2 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 2300388 rplF 3238328 rplF Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L6 YP_187034.1 2299852 R 93062 CDS YP_187035.1 57650820 3238329 complement(2300413..2300811) 1 NC_002951.2 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 2300811 rpsH 3238329 rpsH Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S8 YP_187035.1 2300413 R 93062 CDS YP_187036.1 57650821 3237688 complement(2300843..2301028) 1 NC_002951.2 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 2301028 rpsN 3237688 rpsN Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S14 YP_187036.1 2300843 R 93062 CDS YP_187037.1 57650822 3237689 complement(2301051..2301590) 1 NC_002951.2 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 2301590 rplE 3237689 rplE Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L5 YP_187037.1 2301051 R 93062 CDS YP_187038.1 57650823 3238545 complement(2301617..2301934) 1 NC_002951.2 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 2301934 rplX 3238545 rplX Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L24 YP_187038.1 2301617 R 93062 CDS YP_187039.1 57650824 3238546 complement(2301970..2302338) 1 NC_002951.2 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 2302338 rplN 3238546 rplN Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L14 YP_187039.1 2301970 R 93062 CDS YP_187040.1 57650825 3237306 complement(2302370..2302633) 1 NC_002951.2 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 2302633 rpsQ 3237306 rpsQ Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S17 YP_187040.1 2302370 R 93062 CDS YP_187041.1 57650826 3237307 complement(2302657..2302866) 1 NC_002951.2 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 2302866 rpmC 3237307 rpmC Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L29 YP_187041.1 2302657 R 93062 CDS YP_187042.1 57650827 3236282 complement(2302856..2303290) 1 NC_002951.2 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 2303290 rplP 3236282 rplP Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L16 YP_187042.1 2302856 R 93062 CDS YP_187043.1 57650828 3236283 complement(2303293..2303946) 1 NC_002951.2 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 2303946 rpsC 3236283 rpsC Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S3 YP_187043.1 2303293 R 93062 CDS YP_187044.1 57650829 3237286 complement(2303970..2304323) 1 NC_002951.2 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 2304323 rplV 3237286 rplV Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L22 YP_187044.1 2303970 R 93062 CDS YP_187045.1 57650830 3237287 complement(2304352..2304630) 1 NC_002951.2 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 2304630 rpsS 3237287 rpsS Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S19 YP_187045.1 2304352 R 93062 CDS YP_187046.1 57650831 3237340 complement(2304697..2305530) 1 NC_002951.2 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 2305530 rplB 3237340 rplB Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L2 YP_187046.1 2304697 R 93062 CDS YP_187047.1 57650832 3237341 complement(2305563..2305838) 1 NC_002951.2 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 2305838 rplW 3237341 rplW Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L23 YP_187047.1 2305563 R 93062 CDS YP_187048.1 57650833 3237645 complement(2305838..2306461) 1 NC_002951.2 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 2306461 rplD 3237645 rplD Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L4 YP_187048.1 2305838 R 93062 CDS YP_187049.2 161353538 3237646 complement(2306488..2307150) 1 NC_002951.2 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 2307150 rplC 3237646 rplC Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L3 YP_187049.2 2306488 R 93062 CDS YP_187050.1 57650835 3236278 complement(2307178..2307486) 1 NC_002951.2 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 2307486 rpsJ 3236278 rpsJ Staphylococcus aureus subsp. aureus COL 30S ribosomal protein S10 YP_187050.1 2307178 R 93062 CDS YP_187051.1 57650836 3236279 2307843..2308232 1 NC_002951.2 identified by similarity to GB:AAO05467.1; hypothetical protein 2308232 3236279 SACOL2241 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187051.1 2307843 D 93062 CDS YP_187052.1 57650837 3238467 complement(2308424..2309758) 1 NC_002951.2 identified by match to protein family HMM PF00860; xanthine/uracil permease 2309758 3238467 SACOL2242 Staphylococcus aureus subsp. aureus COL xanthine/uracil permease YP_187052.1 2308424 R 93062 CDS YP_187053.1 57650838 3238468 complement(2309871..2312006) 1 NC_002951.2 decatenates replicating daughter chromosomes; DNA topoisomerase III 2312006 topB 3238468 topB Staphylococcus aureus subsp. aureus COL DNA topoisomerase III YP_187053.1 2309871 R 93062 CDS YP_187054.1 57650839 3237163 2312193..2313080 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 2313080 3237163 SACOL2245 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_187054.1 2312193 D 93062 CDS YP_187055.1 57650840 3237164 2313261..2314124 1 NC_002951.2 identified by match to protein family HMM PF06800; sugar transporter 2314124 3237164 SACOL2246 Staphylococcus aureus subsp. aureus COL sugar transporter YP_187055.1 2313261 D 93062 CDS YP_187056.1 57650841 3237165 complement(2314241..2314372) 1 NC_002951.2 hypothetical protein 2314372 3237165 SACOL2247 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187056.1 2314241 R 93062 CDS YP_187057.1 57650842 3237193 complement(2314543..2315451) 1 NC_002951.2 identified by match to protein family HMM PF03547; hypothetical protein 2315451 3237193 SACOL2248 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187057.1 2314543 R 93062 CDS YP_187058.1 57650843 3237194 2315584..2315748 1 NC_002951.2 hypothetical protein 2315748 3237194 SACOL2250 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187058.1 2315584 D 93062 CDS YP_187059.1 57650844 3238235 2315993..2316310 1 NC_002951.2 identified by similarity to GB:AAO05474.1; hypothetical protein 2316310 3238235 SACOL2251 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187059.1 2315993 D 93062 CDS YP_187060.1 57650845 3238236 complement(2316497..2319664) 1 NC_002951.2 identified by match to protein family HMM PF00873; AcrB/AcrD/AcrF family protein 2319664 3238236 SACOL2252 Staphylococcus aureus subsp. aureus COL AcrB/AcrD/AcrF family protein YP_187060.1 2316497 R 93062 CDS YP_187061.1 57650846 3238237 complement(2319781..2321046) 1 NC_002951.2 identified by match to protein family HMM PF02388; femX protein 2321046 femX 3238237 femX Staphylococcus aureus subsp. aureus COL femX protein YP_187061.1 2319781 R 93062 CDS YP_187062.1 57650847 3237837 complement(2321678..2322442) 1 NC_002951.2 identified by similarity to GB:AAO05477.1; hypothetical protein 2322442 3237837 SACOL2255 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187062.1 2321678 R 93062 CDS YP_187063.1 57650848 3237838 2322604..2323044 1 NC_002951.2 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 2323044 3237838 SACOL2256 Staphylococcus aureus subsp. aureus COL MarR family transcriptional regulator YP_187063.1 2322604 D 93062 CDS YP_187064.1 57650849 3238579 2323037..2324248 1 NC_002951.2 identified by match to protein family HMM PF07690; drug transporter 2324248 3238579 SACOL2257 Staphylococcus aureus subsp. aureus COL drug transporter YP_187064.1 2323037 D 93062 CDS YP_187065.1 57650850 3238580 complement(2324350..2324700) 1 NC_002951.2 identified by similarity to OMNI:SA2258; match to protein family HMM TIGR01889; hypothetical protein 2324700 sarV 3238580 sarV Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187065.1 2324350 R 93062 CDS YP_187066.1 57650851 3236129 2324826..2324996 1 NC_002951.2 hypothetical protein 2324996 3236129 SACOL2259 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187066.1 2324826 D 93062 CDS YP_187067.1 57650852 3236130 complement(2325053..2325196) 1 NC_002951.2 hypothetical protein 2325196 3236130 SACOL2260 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187067.1 2325053 R 93062 CDS YP_187068.1 57650853 3238393 complement(2325391..2326413) 1 NC_002951.2 identified by similarity to EGAD:15818; match to protein family HMM PF04055; match to protein family HMM PF06463; molybdenum cofactor biosynthesis protein A 2326413 moaA 3238393 moaA Staphylococcus aureus subsp. aureus COL molybdenum cofactor biosynthesis protein A YP_187068.1 2325391 R 93062 CDS YP_187069.1 57650854 3238394 complement(2326433..2327032) 1 NC_002951.2 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 2327032 mobA 3238394 mobA Staphylococcus aureus subsp. aureus COL molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_187069.1 2326433 R 93062 CDS YP_187070.1 57650855 3238395 complement(2327039..2327272) 1 NC_002951.2 identified by similarity to GP:3955207; match to protein family HMM PF02597; match to protein family HMM TIGR01682; molybdopterin converting factor subunit 1 2327272 moaD 3238395 moaD Staphylococcus aureus subsp. aureus COL molybdopterin converting factor subunit 1 YP_187070.1 2327039 R 93062 CDS YP_187071.1 57650856 3237589 complement(2327278..2327724) 1 NC_002951.2 identified by similarity to SP:P30749; match to protein family HMM PF02391; molybdenum cofactor biosynthesis protein E 2327724 moaE 3237589 moaE Staphylococcus aureus subsp. aureus COL molybdenum cofactor biosynthesis protein E YP_187071.1 2327278 R 93062 CDS YP_187072.1 57652205 3237396 complement(2327738..2328223) 1 NC_002951.2 identified by similarity to EGAD:107851; match to protein family HMM PF03205; match to protein family HMM TIGR00176; molybdopterin-guanine dinucleotide biosynthesis protein B 2328223 mobB 3237396 mobB Staphylococcus aureus subsp. aureus COL molybdopterin-guanine dinucleotide biosynthesis protein B YP_187072.1 2327738 R 93062 CDS YP_187073.1 57652206 3237397 complement(2328220..2329479) 1 NC_002951.2 identified by similarity to GP:3955204; match to protein family HMM PF00994; match to protein family HMM PF03453; match to protein family HMM PF03454; match to protein family HMM TIGR00177; molybdopterin biosynthesis MoeA protein 2329479 3237397 SACOL2266 Staphylococcus aureus subsp. aureus COL molybdopterin biosynthesis MoeA protein YP_187073.1 2328220 R 93062 CDS YP_187074.1 57652207 3237398 2329542..2330036 1 NC_002951.2 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 2330036 moaC 3237398 moaC Staphylococcus aureus subsp. aureus COL molybdenum cofactor biosynthesis protein MoaC YP_187074.1 2329542 D 93062 CDS YP_187075.1 57652208 3237399 complement(2330038..2330544) 1 NC_002951.2 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; molybdenum cofactor biosynthesis protein B 2330544 moaB 3237399 moaB Staphylococcus aureus subsp. aureus COL molybdenum cofactor biosynthesis protein B YP_187075.1 2330038 R 93062 CDS YP_187076.1 57652209 3237400 complement(2330575..2331579) 1 NC_002951.2 identified by similarity to GP:3955201; match to protein family HMM PF00899; match to protein family HMM PF05237; molybdopterin biosynthesis MoeB protein 2331579 3237400 SACOL2269 Staphylococcus aureus subsp. aureus COL molybdopterin biosynthesis MoeB protein YP_187076.1 2330575 R 93062 CDS YP_187077.1 57652210 3237401 complement(2331749..2332354) 1 NC_002951.2 identified by match to protein family HMM PF00005; molybdenum ABC transporter ATP-binding protein ModC 2332354 modC 3237401 modC Staphylococcus aureus subsp. aureus COL molybdenum ABC transporter ATP-binding protein ModC YP_187077.1 2331749 R 93062 CDS YP_187078.1 57652211 3237402 complement(2332355..2333026) 1 NC_002951.2 identified by similarity to SP:P09834; match to protein family HMM PF00528; match to protein family HMM TIGR02141; molybdenum ABC transporter permease ModB 2333026 modB 3237402 modB Staphylococcus aureus subsp. aureus COL molybdenum ABC transporter permease ModB YP_187078.1 2332355 R 93062 CDS YP_187079.1 57652212 3237388 complement(2333040..2333822) 1 NC_002951.2 identified by similarity to EGAD:13554; match to protein family HMM PF01547; match to protein family HMM TIGR01256; molybdenum ABC transporter molybdenum-binding protein ModA 2333822 modA 3237388 modA Staphylococcus aureus subsp. aureus COL molybdenum ABC transporter molybdenum-binding protein ModA YP_187079.1 2333040 R 93062 CDS YP_187080.1 57652213 3237389 2334112..2334909 1 NC_002951.2 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 2334909 fdhD 3237389 fdhD Staphylococcus aureus subsp. aureus COL formate dehydrogenase accessory protein YP_187080.1 2334112 D 93062 CDS YP_187081.1 57652214 3237390 complement(2335081..2335851) 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 2335851 3237390 SACOL2274 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_187081.1 2335081 R 93062 CDS YP_187082.1 57652215 3237391 complement(2335923..2336477) 1 NC_002951.2 identified by match to protein family HMM PF02632; BioY family protein 2336477 3237391 SACOL2275 Staphylococcus aureus subsp. aureus COL BioY family protein YP_187082.1 2335923 R 93062 CDS YP_187083.1 57652216 3237392 complement(2336598..2337539) 1 NC_002951.2 identified by match to protein family HMM PF01156; inosine-uridine preferring nucleoside hydrolase 2337539 3237392 SACOL2276 Staphylococcus aureus subsp. aureus COL inosine-uridine preferring nucleoside hydrolase YP_187083.1 2336598 R 93062 CDS YP_187084.1 57652217 3237393 complement(2337938..2338846) 1 NC_002951.2 identified by similarity to EGAD:22102; match to protein family HMM PF01497; iron compound ABC transporter iron compound-binding protein 2338846 3237393 SACOL2277 Staphylococcus aureus subsp. aureus COL iron compound ABC transporter iron compound-binding protein YP_187084.1 2337938 R 93062 CDS YP_187085.1 57652218 3237394 complement(2339060..2340214) 1 NC_002951.2 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase-like protein 2340214 3237394 SACOL2278 Staphylococcus aureus subsp. aureus COL acyl-CoA dehydrogenase-like protein YP_187085.1 2339060 R 93062 CDS YP_187086.1 57652219 3237395 complement(2340431..2341336) 1 NC_002951.2 identified by match to protein family HMM PF03253; transporter 2341336 3237395 SACOL2279 Staphylococcus aureus subsp. aureus COL transporter YP_187086.1 2340431 R 93062 CDS YP_187087.1 57652220 3237382 2341596..2341898 1 NC_002951.2 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 2341898 ureA 3237382 ureA Staphylococcus aureus subsp. aureus COL urease subunit gamma YP_187087.1 2341596 D 93062 CDS YP_187088.1 57652221 3237383 2341912..2342322 1 NC_002951.2 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Staphylococcus saprophyticus plays a role in bladder invasiveness and may induce the formation of kidney and bladder stones due to the alkalization of urine; urease subunit beta 2342322 ureB 3237383 ureB Staphylococcus aureus subsp. aureus COL urease subunit beta YP_187088.1 2341912 D 93062 CDS YP_187089.1 57652222 3237384 2342319..2344034 1 NC_002951.2 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 2344034 ureC 3237384 ureC Staphylococcus aureus subsp. aureus COL urease subunit alpha YP_187089.1 2342319 D 93062 CDS YP_187090.1 57652223 3237385 2344047..2344499 1 NC_002951.2 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 2344499 ureE 3237385 ureE Staphylococcus aureus subsp. aureus COL urease accessory protein UreE YP_187090.1 2344047 D 93062 CDS YP_187091.1 57652224 3237386 2344492..2345181 1 NC_002951.2 identified by similarity to EGAD:8726; match to protein family HMM PF01730; urease accessory protein UreF 2345181 ureF 3237386 ureF Staphylococcus aureus subsp. aureus COL urease accessory protein UreF YP_187091.1 2344492 D 93062 CDS YP_187092.1 57652225 3237387 2345194..2345808 1 NC_002951.2 identified by similarity to EGAD:6421; match to protein family HMM PF02492; match to protein family HMM TIGR00101; urease accessory protein UreG 2345808 ureG 3237387 ureG Staphylococcus aureus subsp. aureus COL urease accessory protein UreG YP_187092.1 2345194 D 93062 CDS YP_187093.1 57652226 3237375 2345808..2346644 1 NC_002951.2 identified by similarity to EGAD:7142; match to protein family HMM PF01774; urease accessory protein UreD 2346644 ureD 3237375 ureD Staphylococcus aureus subsp. aureus COL urease accessory protein UreD YP_187093.1 2345808 D 93062 CDS YP_187094.1 57652227 3237376 complement(2346833..2347180) 1 NC_002951.2 identified by similarity to OMNI:SA2287; match to protein family HMM TIGR01889; accessory regulator R 2347180 sarR 3237376 sarR Staphylococcus aureus subsp. aureus COL accessory regulator R YP_187094.1 2346833 R 93062 CDS YP_187095.1 57652228 3237377 complement(2347608..2347934) 1 NC_002951.2 hypothetical protein 2347934 3237377 SACOL2288 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187095.1 2347608 R 93062 CDS YP_187096.1 57652229 3237378 complement(2347998..2348741) 1 NC_002951.2 identified by match to protein family HMM TIGR01889; hypothetical protein 2348741 sarY 3237378 sarY Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187096.1 2347998 R 93062 CDS YP_187097.1 57652230 3237379 complement(2348767..2350722) 1 NC_002951.2 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 2350722 3237379 SACOL2290 Staphylococcus aureus subsp. aureus COL AraC family transcriptional regulator YP_187097.1 2348767 R 93062 CDS YP_187098.1 57652231 3237380 2351332..2352135 1 NC_002951.2 identified by match to protein family HMM PF05257; staphyloxanthin biosynthesis protein 2352135 3237380 SACOL2291 Staphylococcus aureus subsp. aureus COL staphyloxanthin biosynthesis protein YP_187098.1 2351332 D 93062 CDS YP_187099.1 57652232 3237381 complement(2352568..2353968) 1 NC_002951.2 identified by match to protein family HMM PF03553; match to protein family HMM TIGR00931; Na+/H+ antiporter NhaC 2353968 nhaC 3237381 nhaC Staphylococcus aureus subsp. aureus COL Na+/H+ antiporter NhaC YP_187099.1 2352568 R 93062 CDS YP_187100.1 57652233 3237365 complement(2354063..2355145) 1 NC_002951.2 identified by match to protein family HMM PF02317; NAD/NADP octopine/nopaline dehydrogenase 2355145 3237365 SACOL2293 Staphylococcus aureus subsp. aureus COL NAD/NADP octopine/nopaline dehydrogenase YP_187100.1 2354063 R 93062 CDS YP_187101.1 57652234 3237366 2355393..2355815 1 NC_002951.2 hypothetical protein 2355815 3237366 SACOL2294 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187101.1 2355393 D 93062 CDS YP_187102.1 57652235 3237367 2356052..2356552 1 NC_002951.2 identified by match to protein family HMM PF05257; staphyloxanthin biosynthesis protein 2356552 3237367 SACOL2295 Staphylococcus aureus subsp. aureus COL staphyloxanthin biosynthesis protein YP_187102.1 2356052 D 93062 CDS YP_187103.1 57652236 3237368 2356914..2357867 1 NC_002951.2 Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; glycerate dehydrogenase 2357867 3237368 SACOL2296 Staphylococcus aureus subsp. aureus COL glycerate dehydrogenase YP_187103.1 2356914 D 93062 CDS YP_187104.1 57652237 3237369 complement(2357959..2359083) 1 NC_002951.2 identified by match to protein family HMM PF01360; hypothetical protein 2359083 3237369 SACOL2297 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187104.1 2357959 R 93062 CDS YP_187105.1 57652238 3237370 complement(2359394..2360170) 1 NC_002951.2 identified by match to protein family HMM PF01832; N-acetylmuramoyl-L-alanine amidase 2360170 3237370 SACOL2298 Staphylococcus aureus subsp. aureus COL N-acetylmuramoyl-L-alanine amidase YP_187105.1 2359394 R 93062 CDS YP_187106.1 57652239 3237371 complement(2360192..2360443) 1 NC_002951.2 identified by similarity to GB:AAO05523.1; hypothetical protein 2360443 3237371 SACOL2299 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187106.1 2360192 R 93062 CDS YP_187107.1 57652240 3237372 complement(2360653..2361126) 1 NC_002951.2 hypothetical protein 2361126 3237372 SACOL2300 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187107.1 2360653 R 93062 CDS YP_187108.1 57652241 3237357 complement(2361126..2364080) 1 NC_002951.2 identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01591; formate dehydrogenase subunit alpha 2364080 3237357 SACOL2301 Staphylococcus aureus subsp. aureus COL formate dehydrogenase subunit alpha YP_187108.1 2361126 R 93062 CDS YP_187109.1 57652242 3237358 complement(2364682..2365635) 1 NC_002951.2 identified by similarity to EGAD:20070; match to protein family HMM PF03816; match to protein family HMM TIGR00350; transcriptional regulator 2365635 3237358 SACOL2302 Staphylococcus aureus subsp. aureus COL transcriptional regulator YP_187109.1 2364682 R 93062 CDS YP_187110.1 57652243 3237359 complement(2365762..2366559) 1 NC_002951.2 identified by match to protein family HMM PF00459; inositol monophosphatase 2366559 3237359 SACOL2303 Staphylococcus aureus subsp. aureus COL inositol monophosphatase YP_187110.1 2365762 R 93062 CDS YP_187111.1 57652244 3237360 2366944..2367636 1 NC_002951.2 hypothetical protein 2367636 3237360 SACOL2304 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187111.1 2366944 D 93062 CDS YP_187113.1 57652246 3237362 complement(2368283..2369020) 1 NC_002951.2 identified by similarity to GP:10173173; match to protein family HMM PF02517; hypothetical protein 2369020 3237362 SACOL2306 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187113.1 2368283 R 93062 CDS YP_187114.1 57652247 3237363 2369069..2369398 1 NC_002951.2 identified by similarity to GB:AAO05528.1; hypothetical protein 2369398 3237363 SACOL2307 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187114.1 2369069 D 93062 CDS YP_187115.1 57650857 3237590 2369843..2370715 1 NC_002951.2 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; RpiR family phosphosugar-binding transcriptional regulator 2370715 3237590 SACOL2308 Staphylococcus aureus subsp. aureus COL RpiR family phosphosugar-binding transcriptional regulator YP_187115.1 2369843 D 93062 CDS YP_187116.1 57650858 3238057 complement(2371102..2372481) 1 NC_002951.2 identified by match to protein family HMM PF00324; amino acid permease 2372481 3238057 SACOL2309 Staphylococcus aureus subsp. aureus COL amino acid permease YP_187116.1 2371102 R 93062 CDS YP_187117.1 57650859 3238058 2372761..2373117 1 NC_002951.2 identified by similarity to GB:AAO05534.1; hypothetical protein 2373117 3238058 SACOL2310 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187117.1 2372761 D 93062 CDS YP_187118.1 57650860 3236449 2373114..2373299 1 NC_002951.2 hypothetical protein 2373299 3236449 SACOL2311 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187118.1 2373114 D 93062 CDS YP_187119.1 57650861 3236450 complement(2373395..2373586) 1 NC_002951.2 hypothetical protein 2373586 3236450 SACOL2312 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187119.1 2373395 R 93062 CDS YP_187120.1 57650862 3238157 complement(2373597..2374232) 1 NC_002951.2 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; HAD superfamily hydrolase 2374232 3238157 SACOL2313 Staphylococcus aureus subsp. aureus COL HAD superfamily hydrolase YP_187120.1 2373597 R 93062 CDS YP_187121.1 57650863 3238158 complement(2374307..2375224) 1 NC_002951.2 identified by match to protein family HMM PF01758; sodium/bile acid symporter family protein 2375224 3238158 SACOL2314 Staphylococcus aureus subsp. aureus COL sodium/bile acid symporter family protein YP_187121.1 2374307 R 93062 CDS YP_187122.1 57650864 3238159 2375492..2376022 1 NC_002951.2 identified by similarity to GB:AAO05537.1; hypothetical protein 2376022 3238159 SACOL2315 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187122.1 2375492 D 93062 CDS YP_187123.1 57650865 3238004 complement(2376088..2377692) 1 NC_002951.2 identified by match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR02005; PTS system, IIBC components 2377692 3238004 SACOL2316 Staphylococcus aureus subsp. aureus COL PTS system, IIBC components YP_187123.1 2376088 R 93062 CDS YP_187124.1 57650866 3238005 2378022..2378786 1 NC_002951.2 identified by match to protein family HMM PF01380; match to protein family HMM PF01418; phosphosugar-binding transcriptional regulator 2378786 3238005 SACOL2317 Staphylococcus aureus subsp. aureus COL phosphosugar-binding transcriptional regulator YP_187124.1 2378022 D 93062 CDS YP_187125.1 57650867 3238010 complement(2378844..2379350) 1 NC_002951.2 identified by similarity to GB:AAO05542.1; hypothetical protein 2379350 3238010 SACOL2318 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187125.1 2378844 R 93062 CDS YP_187126.1 57650868 3238011 complement(2379517..2380830) 1 NC_002951.2 identified by similarity to OMNI:VCA0193; match to protein family HMM PF03553; Na+/H+ antiporter family protein 2380830 3238011 SACOL2319 Staphylococcus aureus subsp. aureus COL Na+/H+ antiporter family protein YP_187126.1 2379517 R 93062 CDS YP_187127.1 57650869 3238012 complement(2381055..2381624) 1 NC_002951.2 hypothetical protein 2381624 3238012 SACOL2320 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187127.1 2381055 R 93062 CDS YP_187128.1 57650870 3238070 complement(2382111..2382992) 1 NC_002951.2 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase 2382992 3238070 SACOL2321 Staphylococcus aureus subsp. aureus COL short chain dehydrogenase/reductase oxidoreductase YP_187128.1 2382111 R 93062 CDS YP_187129.1 57650871 3238071 complement(2383103..2384224) 1 NC_002951.2 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891; M20/M25/M40 family peptidase 2384224 3238071 SACOL2322 Staphylococcus aureus subsp. aureus COL M20/M25/M40 family peptidase YP_187129.1 2383103 R 93062 CDS YP_187130.1 57650872 3237921 complement(2384501..2385739) 1 NC_002951.2 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase 2385739 hutI 3237921 hutI Staphylococcus aureus subsp. aureus COL imidazolonepropionase YP_187130.1 2384501 R 93062 CDS YP_187131.1 57650873 3237922 complement(2385739..2387400) 1 NC_002951.2 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 2387400 hutU 3237922 hutU Staphylococcus aureus subsp. aureus COL urocanate hydratase YP_187131.1 2385739 R 93062 CDS YP_187132.1 57650874 3238483 2387560..2388444 1 NC_002951.2 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 2388444 3238483 SACOL2325 Staphylococcus aureus subsp. aureus COL LysR family transcriptional regulator YP_187132.1 2387560 D 93062 CDS YP_187133.1 57650875 3238484 2388866..2389285 1 NC_002951.2 catalyzes resistance to fosfomycin by the addition of a thiol cofactor; fosfomycin resistance protein FosB 2389285 fosB 3238484 fosB Staphylococcus aureus subsp. aureus COL fosfomycin resistance protein FosB YP_187133.1 2388866 D 93062 CDS YP_187134.1 57650876 3238442 complement(2389541..2390476) 1 NC_002951.2 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate; formimidoylglutamase 2390476 hutG 3238442 hutG Staphylococcus aureus subsp. aureus COL formimidoylglutamase YP_187134.1 2389541 R 93062 CDS YP_187135.1 57650877 3238443 2390766..2392025 1 NC_002951.2 identified by match to protein family HMM PF02517; hypothetical protein 2392025 3238443 SACOL2328 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187135.1 2390766 D 93062 CDS YP_187136.1 57650878 3238444 complement(2392091..2392777) 1 NC_002951.2 catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 2392777 rpiA 3238444 rpiA Staphylococcus aureus subsp. aureus COL ribose-5-phosphate isomerase A YP_187136.1 2392091 R 93062 CDS YP_187137.1 57650879 3238433 2392951..2393604 1 NC_002951.2 identified by match to protein family HMM PF03473; match to protein family HMM PF03475; hypothetical protein 2393604 3238433 SACOL2330 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187137.1 2392951 D 93062 CDS YP_187138.1 57650880 3238434 complement(2393734..2393847) 1 NC_002951.2 hypothetical protein 2393847 3238434 SACOL2331 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187138.1 2393734 R 93062 CDS YP_187139.1 57650881 3237959 complement(2393840..2394859) 1 NC_002951.2 identified by match to protein family HMM PF01263; aldose 1-epimerase 2394859 galM 3237959 galM Staphylococcus aureus subsp. aureus COL aldose 1-epimerase YP_187139.1 2393840 R 93062 CDS YP_187140.1 57650882 3237960 complement(2394889..2395215) 1 NC_002951.2 identified by match to protein family HMM PF02694; hypothetical protein 2395215 3237960 SACOL2333 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187140.1 2394889 R 93062 CDS YP_187141.1 57650883 3237269 complement(2395433..2396665) 1 NC_002951.2 hypothetical protein 2396665 3237269 SACOL2334 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187141.1 2395433 R 93062 CDS YP_187142.1 57650884 3237270 complement(2396658..2397557) 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2397557 3237270 SACOL2335 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_187142.1 2396658 R 93062 CDS YP_187143.1 57650885 3237271 complement(2397627..2397725) 1 NC_002951.2 hypothetical protein 2397725 3237271 SACOL2336 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187143.1 2397627 R 93062 CDS YP_187144.1 57650886 3237547 complement(2397788..2398435) 1 NC_002951.2 hypothetical protein 2398435 3237547 SACOL2338 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187144.1 2397788 R 93062 CDS YP_187145.1 57650887 3237548 2398834..2399442 1 NC_002951.2 identified by similarity to EGAD:99518; match to protein family HMM PF02245; match to protein family HMM TIGR00567; DNA-3-methyladenine glycosylase 2399442 3237548 SACOL2339 Staphylococcus aureus subsp. aureus COL DNA-3-methyladenine glycosylase YP_187145.1 2398834 D 93062 CDS YP_187146.1 57650888 3237549 2399779..2400987 1 NC_002951.2 identified by match to protein family HMM PF03616; match to protein family HMM TIGR00210; sodium:glutamate symporter 2400987 gltS 3237549 gltS Staphylococcus aureus subsp. aureus COL sodium:glutamate symporter YP_187146.1 2399779 D 93062 CDS YP_187147.1 57650889 3235996 complement(2401035..2402084) 1 NC_002951.2 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 2402084 fni 3235996 fni Staphylococcus aureus subsp. aureus COL isopentenyl pyrophosphate isomerase YP_187147.1 2401035 R 93062 CDS YP_187148.1 57650890 3235997 complement(2402115..2403062) 1 NC_002951.2 identified by match to protein family HMM PF01544; magnesium and cobalt transport protein CorA 2403062 3235997 SACOL2342 Staphylococcus aureus subsp. aureus COL magnesium and cobalt transport protein CorA YP_187148.1 2402115 R 93062 CDS YP_187149.1 57650891 3236039 2403159..2403650 1 NC_002951.2 hypothetical protein 2403650 3236039 SACOL2343 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187149.1 2403159 D 93062 CDS YP_187150.1 57650892 3236040 2403647..2404066 1 NC_002951.2 hypothetical protein 2404066 3236040 SACOL2344 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187150.1 2403647 D 93062 CDS YP_187151.1 57650893 3236041 complement(2404174..2405076) 1 NC_002951.2 identified by similarity to EGAD:16024; esterase 2405076 3236041 SACOL2345 Staphylococcus aureus subsp. aureus COL esterase YP_187151.1 2404174 R 93062 CDS YP_187152.1 57650894 3237947 2405302..2405940 1 NC_002951.2 identified by similarity to GB:AAO05571.1; hypothetical protein 2405940 3237947 SACOL2346 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187152.1 2405302 D 93062 CDS YP_187153.1 57650895 3237948 complement(2406186..2408117) 1 NC_002951.2 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; EmrB/QacA family drug resistance transporter 2408117 3237948 SACOL2347 Staphylococcus aureus subsp. aureus COL EmrB/QacA family drug resistance transporter YP_187153.1 2406186 R 93062 CDS YP_187154.1 57650896 3237949 complement(2408130..2408777) 1 NC_002951.2 hypothetical protein 2408777 3237949 SACOL2348 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187154.1 2408130 R 93062 CDS YP_187155.1 57650897 3237705 2408898..2409449 1 NC_002951.2 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2409449 3237705 SACOL2349 Staphylococcus aureus subsp. aureus COL TetR family transcriptional regulator YP_187155.1 2408898 D 93062 CDS YP_187156.1 57650898 3237706 complement(2409679..2410887) 1 NC_002951.2 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00710; tcaB protein 2410887 tcaB 3237706 tcaB Staphylococcus aureus subsp. aureus COL tcaB protein YP_187156.1 2409679 R 93062 CDS YP_187157.1 57650899 3236066 complement(2410997..2411125) 1 NC_002951.2 hypothetical protein 2411125 3236066 SACOL2351 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187157.1 2410997 R 93062 CDS YP_187158.1 57650900 3236067 complement(2411156..2412538) 1 NC_002951.2 tcaA protein 2412538 tcaA 3236067 tcaA Staphylococcus aureus subsp. aureus COL tcaA protein YP_187158.1 2411156 R 93062 CDS YP_187159.1 57650901 3236068 complement(2412778..2413233) 1 NC_002951.2 identified by match to protein family HMM PF01047; transcriptional regulator TcaR 2413233 tcaR 3236068 tcaR Staphylococcus aureus subsp. aureus COL transcriptional regulator TcaR YP_187159.1 2412778 R 93062 CDS YP_187160.1 57650902 3236430 2413428..2414396 1 NC_002951.2 identified by match to protein family HMM PF02698; hypothetical protein 2414396 3236430 SACOL2354 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187160.1 2413428 D 93062 CDS YP_187161.1 57650903 3236570 complement(2415467..2416132) 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2416132 3236570 SACOL2356 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_187161.1 2415467 R 93062 CDS YP_187162.1 57650904 3236571 complement(2416132..2417187) 1 NC_002951.2 identified by match to protein family HMM PF02687; ABC transporter permease 2417187 3236571 SACOL2357 Staphylococcus aureus subsp. aureus COL ABC transporter permease YP_187162.1 2416132 R 93062 CDS YP_187163.1 57650905 3236572 2417323..2417997 1 NC_002951.2 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 2417997 3236572 SACOL2358 Staphylococcus aureus subsp. aureus COL DNA-binding response regulator YP_187163.1 2417323 D 93062 CDS YP_187164.1 57650906 3238332 2417990..2419363 1 NC_002951.2 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 2419363 3238332 SACOL2359 Staphylococcus aureus subsp. aureus COL sensor histidine kinase YP_187164.1 2417990 D 93062 CDS YP_187165.1 57650907 3238333 2419526..2419969 1 NC_002951.2 identified by match to protein family HMM PF04397; hypothetical protein 2419969 3238333 SACOL2360 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187165.1 2419526 D 93062 CDS YP_187166.1 57650908 3238334 2419966..2420421 1 NC_002951.2 hypothetical protein 2420421 3238334 SACOL2361 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187166.1 2419966 D 93062 CDS YP_187167.1 57650909 3236601 complement(2420487..2421965) 1 NC_002951.2 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 2421965 mqo1 3236601 mqo1 Staphylococcus aureus subsp. aureus COL malate:quinone oxidoreductase YP_187167.1 2420487 R 93062 CDS YP_187168.1 57650910 3236602 complement(2422346..2423944) 1 NC_002951.2 identified by similarity to EGAD:8633; match to protein family HMM PF02652; match to protein family HMM TIGR00795; L-lactate permease 2423944 3236602 SACOL2363 Staphylococcus aureus subsp. aureus COL L-lactate permease YP_187168.1 2422346 R 93062 CDS YP_187169.1 57650911 3238202 2424261..2425934 1 NC_002951.2 identified by similarity to GB:AAO05587.1; hypothetical protein 2425934 3238202 SACOL2364 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187169.1 2424261 D 93062 CDS YP_187170.1 57650912 3238203 complement(2426087..2426716) 1 NC_002951.2 identified by similarity to GB:AAO05588.1; hypothetical protein 2426716 3238203 SACOL2365 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187170.1 2426087 R 93062 CDS YP_187171.1 57650913 3238204 complement(2427030..2427545) 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 2427545 3238204 SACOL2366 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_187171.1 2427030 R 93062 CDS YP_187172.1 57650914 3238547 2427736..2428740 1 NC_002951.2 identified by match to protein family HMM PF00107; alcohol dehydrogenase, zinc-containing 2428740 3238547 SACOL2367 Staphylococcus aureus subsp. aureus COL alcohol dehydrogenase, zinc-containing YP_187172.1 2427736 D 93062 CDS YP_187173.1 57650915 3238548 complement(2428786..2429187) 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 2429187 3238548 SACOL2368 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_187173.1 2428786 R 93062 CDS YP_187174.1 57650916 3238549 complement(2429223..2430257) 1 NC_002951.2 identified by match to protein family HMM PF00070; pyridine nucleotide-disulfide oxidoreductase 2430257 3238549 SACOL2369 Staphylococcus aureus subsp. aureus COL pyridine nucleotide-disulfide oxidoreductase YP_187174.1 2429223 R 93062 CDS YP_187175.1 57650917 3236146 complement(2430489..2430920) 1 NC_002951.2 hypothetical protein 2430920 3236146 SACOL2371 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187175.1 2430489 R 93062 CDS YP_187176.1 57650918 3236147 2430972..2431064 1 NC_002951.2 hypothetical protein 2431064 3236147 SACOL2372 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187176.1 2430972 D 93062 CDS YP_187177.1 57650919 3236148 complement(2431127..2432404) 1 NC_002951.2 hypothetical protein 2432404 3236148 SACOL2373 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187177.1 2431127 R 93062 CDS YP_187178.1 57650920 3237262 2432565..2433188 1 NC_002951.2 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2433188 3237262 SACOL2374 Staphylococcus aureus subsp. aureus COL TetR family transcriptional regulator YP_187178.1 2432565 D 93062 CDS YP_187179.1 57650921 3237263 2433234..2434178 1 NC_002951.2 identified by match to protein family HMM PF01544; CorA family protein 2434178 3237263 SACOL2375 Staphylococcus aureus subsp. aureus COL CorA family protein YP_187179.1 2433234 D 93062 CDS YP_187180.1 57650922 3237264 complement(2434264..2435706) 1 NC_002951.2 identified by similarity to EGAD:18969; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR01996; PTS system, sucrose-specific IIBC components 2435706 3237264 SACOL2376 Staphylococcus aureus subsp. aureus COL PTS system, sucrose-specific IIBC components YP_187180.1 2434264 R 93062 CDS YP_187181.1 57650923 3237626 2435889..2436272 1 NC_002951.2 identified by similarity to GB:AAO05601.1; hypothetical protein 2436272 3237626 SACOL2377 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187181.1 2435889 D 93062 CDS YP_187182.1 57650924 3237627 2437760..2439865 1 NC_002951.2 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 2439865 3237627 SACOL2378 Staphylococcus aureus subsp. aureus COL AraC family transcriptional regulator YP_187182.1 2437760 D 93062 CDS YP_187183.1 57650925 3237628 2439936..2440358 1 NC_002951.2 identified by similarity to EGAD:107318; match to protein family HMM PF01243; hypothetical protein 2440358 3237628 SACOL2379 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187183.1 2439936 D 93062 CDS YP_187184.1 57650926 3238523 complement(2440454..2440576) 1 NC_002951.2 hypothetical protein 2440576 3238523 SACOL2380 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187184.1 2440454 R 93062 CDS YP_187185.1 57650927 3238524 2440623..2440979 1 NC_002951.2 identified by similarity to GB:AAO05604.1; hypothetical protein 2440979 3238524 SACOL2381 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187185.1 2440623 D 93062 CDS YP_187186.1 57650928 3238525 complement(2441383..2442660) 1 NC_002951.2 identified by similarity to EGAD:7647; match to protein family HMM PF00375; proton/sodium-glutamate symport protein 2442660 3238525 SACOL2382 Staphylococcus aureus subsp. aureus COL proton/sodium-glutamate symport protein YP_187186.1 2441383 R 93062 CDS YP_187187.1 57650929 3238644 complement(2442842..2443207) 1 NC_002951.2 identified by similarity to GB:AAO05606.1; hypothetical protein 2443207 3238644 SACOL2383 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187187.1 2442842 R 93062 CDS YP_187188.1 57650930 3238645 2443605..2444051 1 NC_002951.2 identified by match to protein family HMM PF01047; accessory protein Z 2444051 sarZ 3238645 sarZ Staphylococcus aureus subsp. aureus COL accessory protein Z YP_187188.1 2443605 D 93062 CDS YP_187189.1 57650931 3238646 2444267..2444695 1 NC_002951.2 identified by match to protein family HMM PF00011; HSP20 family protein 2444695 3238646 SACOL2385 Staphylococcus aureus subsp. aureus COL HSP20 family protein YP_187189.1 2444267 D 93062 CDS YP_187190.1 57650932 3236198 complement(2444802..2445971) 1 NC_002951.2 identified by similarity to EGAD:30454; match to protein family HMM PF07690; nitrite extrusion protein 2445971 3236198 SACOL2386 Staphylococcus aureus subsp. aureus COL nitrite extrusion protein YP_187190.1 2444802 R 93062 CDS YP_187191.1 57650933 3236205 2447234..2447974 1 NC_002951.2 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 2447974 3236205 SACOL2388 Staphylococcus aureus subsp. aureus COL MerR family transcriptional regulator YP_187191.1 2447234 D 93062 CDS YP_187192.1 57650934 3236206 complement(2448232..2448885) 1 NC_002951.2 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; transcriptional regulatory protein DegU 2448885 3236206 SACOL2389 Staphylococcus aureus subsp. aureus COL transcriptional regulatory protein DegU YP_187192.1 2448232 R 93062 CDS YP_187193.1 57650935 3236207 complement(2448908..2449942) 1 NC_002951.2 identified by match to protein family HMM PF02518; sensory box histidine kinase 2449942 3236207 SACOL2390 Staphylococcus aureus subsp. aureus COL sensory box histidine kinase YP_187193.1 2448908 R 93062 CDS YP_187194.1 57650936 3238246 complement(2449966..2450418) 1 NC_002951.2 identified by similarity to GB:AAO05612.1; hypothetical protein 2450418 3238246 SACOL2391 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187194.1 2449966 R 93062 CDS YP_187195.1 57650937 3238247 complement(2450438..2451115) 1 NC_002951.2 identified by similarity to EGAD:30704; match to protein family HMM PF02665; match to protein family HMM TIGR00351; respiratory nitrate reductase subunit gamma 2451115 narI 3238247 narI Staphylococcus aureus subsp. aureus COL respiratory nitrate reductase subunit gamma YP_187195.1 2450438 R 93062 CDS YP_187196.1 57650938 3238248 complement(2451108..2451698) 1 NC_002951.2 identified by match to protein family HMM PF02613; match to protein family HMM TIGR00684; respiratory nitrate reductase subunit delta 2451698 narJ 3238248 narJ Staphylococcus aureus subsp. aureus COL respiratory nitrate reductase subunit delta YP_187196.1 2451108 R 93062 CDS YP_187197.1 57650939 3238628 complement(2451676..2453235) 1 NC_002951.2 identified by similarity to EGAD:16236; similarity to EGAD:30703; match to protein family HMM TIGR01660; respiratory nitrate reductase subunit beta 2453235 narH 3238628 narH Staphylococcus aureus subsp. aureus COL respiratory nitrate reductase subunit beta YP_187197.1 2451676 R 93062 CDS YP_187198.1 57650940 3238629 complement(2453225..2456914) 1 NC_002951.2 identified by similarity to EGAD:30702; match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580; respiratory nitrate reductase subunit alpha 2456914 narG 3238629 narG Staphylococcus aureus subsp. aureus COL respiratory nitrate reductase subunit alpha YP_187198.1 2453225 R 93062 CDS YP_187199.1 57650941 3238630 complement(2457224..2458201) 1 NC_002951.2 identified by similarity to GP:4433641; match to protein family HMM PF00590; match to protein family HMM TIGR01469; uroporphyrinogen III methylase SirB 2458201 3238630 SACOL2396 Staphylococcus aureus subsp. aureus COL uroporphyrinogen III methylase SirB YP_187199.1 2457224 R 93062 CDS YP_187200.1 57650942 3236579 complement(2458192..2458506) 1 NC_002951.2 identified by similarity to EGAD:30823; match to protein family HMM PF00355; nitrite reductase [NAD(P)H], small subunit 2458506 nirD 3236579 nirD Staphylococcus aureus subsp. aureus COL nitrite reductase [NAD(P)H], small subunit YP_187200.1 2458192 R 93062 CDS YP_187201.1 57650943 3236580 complement(2458510..2460915) 1 NC_002951.2 identified by similarity to EGAD:30822; match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; nitrite reductase [NAD(P)H], large subunit 2460915 nirB 3236580 nirB Staphylococcus aureus subsp. aureus COL nitrite reductase [NAD(P)H], large subunit YP_187201.1 2458510 R 93062 CDS YP_187202.1 57650944 3236581 complement(2460981..2461712) 1 NC_002951.2 identified by similarity to GP:4433637; transcriptional regulator NirR 2461712 nirR 3236581 nirR Staphylococcus aureus subsp. aureus COL transcriptional regulator NirR YP_187202.1 2460981 R 93062 CDS YP_187203.1 57650945 3236035 complement(2461942..2462478) 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 2462478 3236035 SACOL2400 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_187203.1 2461942 R 93062 CDS YP_187204.1 57650946 3236036 complement(2462711..2463535) 1 NC_002951.2 identified by match to protein family HMM PF01226; formate/nitrite transporter family protein 2463535 3236036 SACOL2401 Staphylococcus aureus subsp. aureus COL formate/nitrite transporter family protein YP_187204.1 2462711 R 93062 CDS YP_187205.1 57650947 3236037 complement(2464018..2464485) 1 NC_002951.2 identified by similarity to GP:3294247; hypothetical protein 2464485 3236037 SACOL2402 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187205.1 2464018 R 93062 CDS YP_187206.1 57650948 3236038 complement(2464671..2466221) 1 NC_002951.2 identified by match to protein family HMM PF01297; ABC transporter substrate-binding protein 2466221 3236038 SACOL2403 Staphylococcus aureus subsp. aureus COL ABC transporter substrate-binding protein YP_187206.1 2464671 R 93062 CDS YP_187207.1 57650949 3238588 complement(2466516..2466782) 1 NC_002951.2 identified by match to protein family HMM PF06769; match to protein family HMM TIGR02116; addiction module antitoxin 2466782 3238588 SACOL2404 Staphylococcus aureus subsp. aureus COL addiction module antitoxin YP_187207.1 2466516 R 93062 CDS YP_187208.1 57650950 3238589 complement(2466782..2467033) 1 NC_002951.2 identified by match to protein family HMM PF02604; match to protein family HMM TIGR01552; addiction module antitoxin 2467033 3238589 SACOL2405 Staphylococcus aureus subsp. aureus COL addiction module antitoxin YP_187208.1 2466782 R 93062 CDS YP_187209.1 57650951 3238590 complement(2467198..2467296) 1 NC_002951.2 hypothetical protein 2467296 3238590 SACOL2406 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187209.1 2467198 R 93062 CDS YP_187210.1 57650952 3238591 complement(2467306..2467905) 1 NC_002951.2 identified by similarity to EGAD:109043; match to protein family HMM PF01323; lipoprotein 2467905 3238591 SACOL2407 Staphylococcus aureus subsp. aureus COL lipoprotein YP_187210.1 2467306 R 93062 CDS YP_187211.1 57650953 3238632 complement(2467924..2468295) 1 NC_002951.2 identified by similarity to GB:AAO05629.1; lipoprotein 2468295 3238632 SACOL2408 Staphylococcus aureus subsp. aureus COL lipoprotein YP_187211.1 2467924 R 93062 CDS YP_187212.1 57650954 3238633 2468541..2469791 1 NC_002951.2 identified by similarity to GP:4574233; match to protein family HMM PF02388; fmhA protein 2469791 fmhA 3238633 fmhA Staphylococcus aureus subsp. aureus COL fmhA protein YP_187212.1 2468541 D 93062 CDS YP_187213.1 57650955 3238634 complement(2469888..2470619) 1 NC_002951.2 identified by match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 2470619 3238634 SACOL2410 Staphylococcus aureus subsp. aureus COL amino acid ABC transporter ATP-binding protein YP_187213.1 2469888 R 93062 CDS YP_187214.1 57650956 3238153 complement(2470616..2471344) 1 NC_002951.2 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 2471344 3238153 SACOL2411 Staphylococcus aureus subsp. aureus COL amino acid ABC transporter permease YP_187214.1 2470616 R 93062 CDS YP_187215.1 57650957 3238154 complement(2471316..2472095) 1 NC_002951.2 identified by match to protein family HMM PF00497; amino acid ABC transporter amino acid-binding protein 2472095 3238154 SACOL2412 Staphylococcus aureus subsp. aureus COL amino acid ABC transporter amino acid-binding protein YP_187215.1 2471316 R 93062 CDS YP_187216.1 57650958 3238155 complement(2472216..2473613) 1 NC_002951.2 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711; EmrB/QacA family drug resistance transporter 2473613 3238155 SACOL2413 Staphylococcus aureus subsp. aureus COL EmrB/QacA family drug resistance transporter YP_187216.1 2472216 R 93062 CDS YP_187217.1 57650959 3238156 2473830..2473934 1 NC_002951.2 identified by similarity to GB:AAO05635.1; hypothetical protein 2473934 3238156 SACOL2414 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187217.1 2473830 D 93062 CDS YP_187218.1 57650960 3238336 complement(2474088..2474774) 1 NC_002951.2 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 2474774 gpmA 3238336 gpmA Staphylococcus aureus subsp. aureus COL phosphoglyceromutase YP_187218.1 2474088 R 93062 CDS YP_187219.1 57650961 3238337 complement(2475100..2475966) 1 NC_002951.2 identified by match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux family protein 2475966 3238337 SACOL2416 Staphylococcus aureus subsp. aureus COL cation efflux family protein YP_187219.1 2475100 R 93062 CDS YP_187220.1 57650962 3238338 2476718..2478028 1 NC_002951.2 identified by similarity to OMNI:SA2418; match to protein family HMM PF02216; IgG-binding protein SBI 2478028 3238338 SACOL2418 Staphylococcus aureus subsp. aureus COL IgG-binding protein SBI YP_187220.1 2476718 D 93062 CDS YP_187221.1 57650963 3238445 2478564..2479493 1 NC_002951.2 identified by similarity to OMNI:SA2419; match to protein family HMM PF01117; match to protein family HMM TIGR01002; gamma-hemolysin, component A 2479493 hlgA 3238445 hlgA Staphylococcus aureus subsp. aureus COL gamma-hemolysin, component A YP_187221.1 2478564 D 93062 CDS YP_187222.1 57650964 3238446 2479557..2479682 1 NC_002951.2 hypothetical protein 2479682 3238446 SACOL2420 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187222.1 2479557 D 93062 CDS YP_187223.1 57650965 3238447 2480061..2481008 1 NC_002951.2 identified by similarity to SP:P31716; match to protein family HMM PF01117; match to protein family HMM TIGR01002; gamma hemolysin, component C 2481008 hlgC 3238447 hlgC Staphylococcus aureus subsp. aureus COL gamma hemolysin, component C YP_187223.1 2480061 D 93062 CDS YP_187224.1 57650966 3238448 2481010..2481987 1 NC_002951.2 identified by similarity to SP:P31715; match to protein family HMM PF01117; match to protein family HMM TIGR01002; gamma hemolysin, component B 2481987 hlgB 3238448 hlgB Staphylococcus aureus subsp. aureus COL gamma hemolysin, component B YP_187224.1 2481010 D 93062 CDS YP_187225.1 57650967 3238617 complement(2482039..2482506) 1 NC_002951.2 identified by similarity to EGAD:19942; hypothetical protein 2482506 3238617 SACOL2423 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187225.1 2482039 R 93062 CDS YP_187226.1 57650968 3238618 complement(2482517..2483209) 1 NC_002951.2 catalyzes the formation of pimeloyl-CoA from pimelate and coenzyme A; 6-carboxyhexanoate--CoA ligase 2483209 bioW 3238618 bioW Staphylococcus aureus subsp. aureus COL 6-carboxyhexanoate--CoA ligase YP_187226.1 2482517 R 93062 CDS YP_187227.1 57650969 3238619 complement(2483220..2484335) 1 NC_002951.2 identified by similarity to EGAD:45705; match to protein family HMM PF00155; 8-amino-7-oxononanoate synthase 2484335 3238619 SACOL2425 Staphylococcus aureus subsp. aureus COL 8-amino-7-oxononanoate synthase YP_187227.1 2483220 R 93062 CDS YP_187228.1 57650970 3238608 complement(2484313..2485320) 1 NC_002951.2 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine; biotin synthase 2485320 bioB 3238608 bioB Staphylococcus aureus subsp. aureus COL biotin synthase YP_187228.1 2484313 R 93062 CDS YP_187229.1 57650971 3238609 complement(2485322..2486680) 1 NC_002951.2 identified by similarity to EGAD:45704; match to protein family HMM PF00202; match to protein family HMM TIGR00508; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 2486680 bioA 3238609 bioA Staphylococcus aureus subsp. aureus COL adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_187229.1 2485322 R 93062 CDS YP_187230.1 57650972 3238610 complement(2486658..2487344) 1 NC_002951.2 identified by similarity to SP:Q58695; match to protein family HMM TIGR00347; dethiobiotin synthase 2487344 bioD 3238610 bioD Staphylococcus aureus subsp. aureus COL dethiobiotin synthase YP_187230.1 2486658 R 93062 CDS YP_187231.1 57650973 3238689 complement(2487565..2487708) 1 NC_002951.2 hypothetical protein 2487708 3238689 SACOL2429 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187231.1 2487565 R 93062 CDS YP_187232.1 57650974 3238690 complement(2487796..2489529) 1 NC_002951.2 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 2489529 3238690 SACOL2430 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein/permease YP_187232.1 2487796 R 93062 CDS YP_187233.1 57650975 3238691 complement(2489554..2491317) 1 NC_002951.2 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding protein/permease 2491317 3238691 SACOL2431 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein/permease YP_187233.1 2489554 R 93062 CDS YP_187234.1 57650976 3238692 complement(2491945..2492052) 1 NC_002951.2 hypothetical protein 2492052 3238692 SACOL2433 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187234.1 2491945 R 93062 CDS YP_187235.1 57650977 3238053 complement(2492187..2492573) 1 NC_002951.2 identified by similarity to GP:13162065; match to protein family HMM PF04138; hypothetical protein 2492573 3238053 SACOL2434 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187235.1 2492187 R 93062 CDS YP_187236.1 57650978 3238054 2492841..2493983 1 NC_002951.2 identified by similarity to OMNI:NTL01BH0556; match to protein family HMM PF02595; match to protein family HMM TIGR00045; glycerate kinase 2493983 3238054 SACOL2435 Staphylococcus aureus subsp. aureus COL glycerate kinase YP_187236.1 2492841 D 93062 CDS YP_187237.1 57652248 3237364 2494043..2494702 1 NC_002951.2 identified by similarity to GB:AAO05641.1; hypothetical protein 2494702 3237364 SACOL2436 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187237.1 2494043 D 93062 CDS YP_187238.1 57652249 3237258 2494884..2496095 1 NC_002951.2 identified by similarity to SP:P28246; match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00710; bicyclomycin resistance protein 2496095 bcr 3237258 bcr Staphylococcus aureus subsp. aureus COL bicyclomycin resistance protein YP_187238.1 2494884 D 93062 CDS YP_187239.1 57652250 3237259 complement(2496218..2496691) 1 NC_002951.2 identified by match to protein family HMM PF06445; hypothetical protein 2496691 3237259 SACOL2438 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187239.1 2496218 R 93062 CDS YP_187240.1 57652251 3237351 2496804..2497460 1 NC_002951.2 identified by similarity to GB:AAO05643.1; hypothetical protein 2497460 3237351 SACOL2439 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187240.1 2496804 D 93062 CDS YP_187241.1 57652252 3237352 complement(2497523..2498329) 1 NC_002951.2 identified by match to protein family HMM PF00149; hypothetical protein 2498329 3237352 SACOL2440 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187241.1 2497523 R 93062 CDS YP_187242.1 57652253 3237353 2498615..2500024 1 NC_002951.2 identified by match to protein family HMM PF00324; amino acid permease 2500024 3237353 SACOL2441 Staphylococcus aureus subsp. aureus COL amino acid permease YP_187242.1 2498615 D 93062 CDS YP_187243.1 57652254 3237354 2500162..2502240 1 NC_002951.2 identified by match to protein family HMM PF00999; Na+/H+ antiporter 2502240 3237354 SACOL2442 Staphylococcus aureus subsp. aureus COL Na+/H+ antiporter YP_187243.1 2500162 D 93062 CDS YP_187244.1 57652255 3237355 complement(2502380..2504209) 1 NC_002951.2 hypothetical protein 2504209 3237355 SACOL2443 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187244.1 2502380 R 93062 CDS YP_187245.1 57652256 3237356 2504441..2505937 1 NC_002951.2 identified by similarity to GP:9246437; match to protein family HMM PF00144; fmtA-like protein 2505937 3237356 SACOL2445 Staphylococcus aureus subsp. aureus COL fmtA-like protein YP_187245.1 2504441 D 93062 CDS YP_187246.1 57652257 3237251 complement(2506029..2506880) 1 NC_002951.2 epimerase/dehydratase 2506880 3237251 SACOL2446 Staphylococcus aureus subsp. aureus COL epimerase/dehydratase YP_187246.1 2506029 R 93062 CDS YP_187247.1 57652258 3237252 complement(2507202..2508137) 1 NC_002951.2 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 2508137 3237252 SACOL2448 Staphylococcus aureus subsp. aureus COL 2-dehydropantoate 2-reductase YP_187247.1 2507202 R 93062 CDS YP_187248.1 57652259 3237253 complement(2508363..2509763) 1 NC_002951.2 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; drug transporter 2509763 3237253 SACOL2449 Staphylococcus aureus subsp. aureus COL drug transporter YP_187248.1 2508363 R 93062 CDS YP_187249.1 57652260 3237254 complement(2510057..2510752) 1 NC_002951.2 identified by match to protein family HMM PF00528; amino acid ABC transporter permease 2510752 3237254 SACOL2450 Staphylococcus aureus subsp. aureus COL amino acid ABC transporter permease YP_187249.1 2510057 R 93062 CDS YP_187250.1 57652261 3237255 complement(2510752..2511693) 1 NC_002951.2 identified by match to protein family HMM PF04069; amino acid ABC transporter amino acid-binding protein 2511693 3237255 SACOL2451 Staphylococcus aureus subsp. aureus COL amino acid ABC transporter amino acid-binding protein YP_187250.1 2510752 R 93062 CDS YP_187251.1 57652262 3237256 complement(2511710..2512345) 1 NC_002951.2 identified by match to protein family HMM PF00528; amino acid ABC transporter permease 2512345 3237256 SACOL2452 Staphylococcus aureus subsp. aureus COL amino acid ABC transporter permease YP_187251.1 2511710 R 93062 CDS YP_187252.1 57652263 3237257 complement(2512342..2513568) 1 NC_002951.2 identified by match to protein family HMM PF00005; match to protein family HMM PF00571; match to protein family HMM TIGR01186; amino acid ABC transporter ATP-binding protein 2513568 3237257 SACOL2453 Staphylococcus aureus subsp. aureus COL amino acid ABC transporter ATP-binding protein YP_187252.1 2512342 R 93062 CDS YP_187253.1 57652264 3237243 complement(2513895..2514014) 1 NC_002951.2 hypothetical protein 2514014 3237243 SACOL2454 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187253.1 2513895 R 93062 CDS YP_187254.1 57652265 3237244 complement(2514238..2514837) 1 NC_002951.2 identified by similarity to GP:4514322; hypothetical protein 2514837 3237244 SACOL2456 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187254.1 2514238 R 93062 CDS YP_187255.1 57652266 3237245 complement(2514830..2515000) 1 NC_002951.2 hypothetical protein 2515000 3237245 SACOL2457 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187255.1 2514830 R 93062 CDS YP_187256.1 57652267 3237246 2515017..2516654 1 NC_002951.2 identified by match to protein family HMM PF00324; amino acid permease 2516654 3237246 SACOL2458 Staphylococcus aureus subsp. aureus COL amino acid permease YP_187256.1 2515017 D 93062 CDS YP_187257.1 57652268 3237247 2517262..2518614 1 NC_002951.2 identified by similarity to SP:P37967; match to protein family HMM PF00135; para-nitrobenzyl esterase 2518614 pnbA 3237247 pnbA Staphylococcus aureus subsp. aureus COL para-nitrobenzyl esterase YP_187257.1 2517262 D 93062 CDS YP_187258.1 57652269 3237248 complement(2518676..2519863) 1 NC_002951.2 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; drug transporter 2519863 3237248 SACOL2460 Staphylococcus aureus subsp. aureus COL drug transporter YP_187258.1 2518676 R 93062 CDS YP_187259.1 57652270 3237249 complement(2520259..2521035) 1 NC_002951.2 identified by similarity to SP:P77307; match to protein family HMM PF03649; match to protein family HMM TIGR00245; hypothetical protein 2521035 3237249 SACOL2461 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187259.1 2520259 R 93062 CDS YP_187260.1 57652271 3237250 complement(2521028..2521690) 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2521690 3237250 SACOL2462 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_187260.1 2521028 R 93062 CDS YP_187261.1 57652272 3237234 complement(2521938..2523014) 1 NC_002951.2 identified by similarity to EGAD:40297; match to protein family HMM PF05343; glutamyl-aminopeptidase 2523014 pepA2 3237234 pepA2 Staphylococcus aureus subsp. aureus COL glutamyl-aminopeptidase YP_187261.1 2521938 R 93062 CDS YP_187262.1 57652273 3237235 complement(2523369..2523635) 1 NC_002951.2 identified by match to protein family HMM TIGR02116; addiction module antitoxin 2523635 3237235 SACOL2464 Staphylococcus aureus subsp. aureus COL addiction module antitoxin YP_187262.1 2523369 R 93062 CDS YP_187263.1 57652274 3237236 complement(2523635..2523892) 1 NC_002951.2 identified by match to protein family HMM PF02604; match to protein family HMM TIGR01552; addiction module antitoxin 2523892 3237236 SACOL2465 Staphylococcus aureus subsp. aureus COL addiction module antitoxin YP_187263.1 2523635 R 93062 CDS YP_187264.1 57652275 3237237 complement(2523998..2524192) 1 NC_002951.2 hypothetical protein 2524192 3237237 SACOL2466 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187264.1 2523998 R 93062 CDS YP_187265.1 57652276 3237238 2524251..2524706 1 NC_002951.2 identified by match to protein family HMM PF06998; lipoprotein 2524706 3237238 SACOL2467 Staphylococcus aureus subsp. aureus COL lipoprotein YP_187265.1 2524251 D 93062 CDS YP_187266.1 57652277 3237239 complement(2524874..2526451) 1 NC_002951.2 identified by match to protein family HMM PF01645; glutamate synthase 2526451 3237239 SACOL2469 Staphylococcus aureus subsp. aureus COL glutamate synthase YP_187266.1 2524874 R 93062 CDS YP_187267.1 57652278 3237240 2526646..2527395 1 NC_002951.2 hypothetical protein 2527395 3237240 SACOL2470 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187267.1 2526646 D 93062 CDS YP_187268.1 57652279 3237241 complement(2527619..2528812) 1 NC_002951.2 identified by similarity to GP:10174698; match to protein family HMM PF07690; transporter 2528812 3237241 SACOL2471 Staphylococcus aureus subsp. aureus COL transporter YP_187268.1 2527619 R 93062 CDS YP_187269.1 57652280 3237227 complement(2528824..2529573) 1 NC_002951.2 identified by match to protein family HMM PF00005; peptide ABC transporter ATP-binding protein 2529573 3237227 SACOL2472 Staphylococcus aureus subsp. aureus COL peptide ABC transporter ATP-binding protein YP_187269.1 2528824 R 93062 CDS YP_187270.1 57652281 3237228 complement(2529566..2530381) 1 NC_002951.2 identified by match to protein family HMM PF00005; peptide ABC transporter ATP-binding protein 2530381 3237228 SACOL2473 Staphylococcus aureus subsp. aureus COL peptide ABC transporter ATP-binding protein YP_187270.1 2529566 R 93062 CDS YP_187271.1 57652282 3237229 complement(2530378..2531247) 1 NC_002951.2 identified by match to protein family HMM PF00528; peptide ABC transporter permease 2531247 3237229 SACOL2474 Staphylococcus aureus subsp. aureus COL peptide ABC transporter permease YP_187271.1 2530378 R 93062 CDS YP_187272.1 57652283 3237230 complement(2531244..2532179) 1 NC_002951.2 identified by match to protein family HMM PF00528; peptide ABC transporter permease 2532179 3237230 SACOL2475 Staphylococcus aureus subsp. aureus COL peptide ABC transporter permease YP_187272.1 2531244 R 93062 CDS YP_187273.1 57652284 3237231 complement(2532192..2533790) 1 NC_002951.2 identified by match to protein family HMM PF00496; match to protein family HMM TIGR02294; peptide ABC transporter peptide-binding protein 2533790 3237231 SACOL2476 Staphylococcus aureus subsp. aureus COL peptide ABC transporter peptide-binding protein YP_187273.1 2532192 R 93062 CDS YP_187274.1 57652285 3237232 complement(2533933..2535147) 1 NC_002951.2 hypothetical protein 2535147 3237232 SACOL2477 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187274.1 2533933 R 93062 CDS YP_187275.1 57650979 3238055 complement(2535227..2536045) 1 NC_002951.2 identified by similarity to OMNI:NTL01BH2075; hypothetical protein 2536045 3238055 SACOL2478 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187275.1 2535227 R 93062 CDS YP_187276.1 57650980 3238056 complement(2536056..2536877) 1 NC_002951.2 identified by similarity to GP:10174690; hypothetical protein 2536877 3238056 SACOL2479 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187276.1 2536056 R 93062 CDS YP_187277.1 57650981 3238541 complement(2537025..2537156) 1 NC_002951.2 hypothetical protein 2537156 3238541 SACOL2480 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187277.1 2537025 R 93062 CDS YP_187278.1 57650982 3238542 complement(2537620..2537985) 1 NC_002951.2 hypothetical protein 2537985 3238542 SACOL2481 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187278.1 2537620 R 93062 CDS YP_187279.1 57650983 3238560 2539299..2540837 1 NC_002951.2 identified by match to protein family HMM PF03806; transporter 2540837 3238560 SACOL2483 Staphylococcus aureus subsp. aureus COL transporter YP_187279.1 2539299 D 93062 CDS YP_187280.1 57650984 3238561 complement(2540949..2541371) 1 NC_002951.2 identified by match to protein family HMM TIGR00778; alkylhydroperoxidase 2541371 3238561 SACOL2484 Staphylococcus aureus subsp. aureus COL alkylhydroperoxidase YP_187280.1 2540949 R 93062 CDS YP_187281.1 57650985 3238562 complement(2541823..2542242) 1 NC_002951.2 hypothetical protein 2542242 3238562 SACOL2485 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187281.1 2541823 R 93062 CDS YP_187282.1 57650986 3238116 complement(2542260..2542679) 1 NC_002951.2 hypothetical protein 2542679 3238116 SACOL2486 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187282.1 2542260 R 93062 CDS YP_187283.1 57650987 3238117 complement(2542946..2543368) 1 NC_002951.2 identified by similarity to GB:AAO03749.1; match to protein family HMM PF07252; hypothetical protein 2543368 3238117 SACOL2487 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187283.1 2542946 R 93062 CDS YP_187284.1 57650988 3238118 complement(2543619..2544314) 1 NC_002951.2 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase 2544314 3238118 SACOL2488 Staphylococcus aureus subsp. aureus COL short chain dehydrogenase/reductase oxidoreductase YP_187284.1 2543619 R 93062 CDS YP_187285.1 57650989 3238119 2544762..2544884 1 NC_002951.2 identified by similarity to GB:AAO05678.1; hypothetical protein 2544884 3238119 SACOL2489 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187285.1 2544762 D 93062 CDS YP_187286.1 57650990 3238313 complement(2545144..2545335) 1 NC_002951.2 identified by similarity to GB:AAO05679.1; hypothetical protein 2545335 3238313 SACOL2491 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187286.1 2545144 R 93062 CDS YP_187287.1 57650991 3238314 2545770..2545892 1 NC_002951.2 hypothetical protein 2545892 3238314 SACOL2492 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187287.1 2545770 D 93062 CDS YP_187288.1 57650992 3238315 complement(2545896..2546690) 1 NC_002951.2 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742; hypothetical protein 2546690 3238315 SACOL2493 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187288.1 2545896 R 93062 CDS YP_187289.1 57650993 3238486 complement(2547226..2547513) 1 NC_002951.2 hypothetical protein 2547513 3238486 SACOL2494 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187289.1 2547226 R 93062 CDS YP_187290.1 57650994 3238487 complement(2547516..2547842) 1 NC_002951.2 hypothetical protein 2547842 3238487 SACOL2495 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187290.1 2547516 R 93062 CDS YP_187291.1 57650995 3238488 complement(2548054..2549166) 1 NC_002951.2 hypothetical protein 2549166 3238488 SACOL2496 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187291.1 2548054 R 93062 CDS YP_187292.1 57650996 3238489 complement(2549163..2549948) 1 NC_002951.2 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742; hypothetical protein 2549948 3238489 SACOL2497 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187292.1 2549163 R 93062 CDS YP_187293.1 57650997 3238428 complement(2550060..2550836) 1 NC_002951.2 identified by match to protein family HMM PF04507; match to protein family HMM TIGR01742; hypothetical protein 2550836 3238428 SACOL2498 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187293.1 2550060 R 93062 CDS YP_187294.1 57650998 3238429 complement(2551139..2554000) 1 NC_002951.2 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851; helicase 2554000 3238429 SACOL2499 Staphylococcus aureus subsp. aureus COL helicase YP_187294.1 2551139 R 93062 CDS YP_187295.1 57650999 3238430 complement(2554002..2554394) 1 NC_002951.2 identified by match to protein family HMM PF00293; MutT/nudix family protein 2554394 3238430 SACOL2500 Staphylococcus aureus subsp. aureus COL MutT/nudix family protein YP_187295.1 2554002 R 93062 CDS YP_187296.1 57651000 3238431 2554511..2556319 1 NC_002951.2 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphoglucomutase/phosphomannomutase 2556319 3238431 SACOL2501 Staphylococcus aureus subsp. aureus COL phosphoglucomutase/phosphomannomutase YP_187296.1 2554511 D 93062 CDS YP_187297.1 57651001 3238260 2556603..2556869 1 NC_002951.2 hypothetical protein 2556869 3238260 SACOL2502 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187297.1 2556603 D 93062 CDS YP_187298.1 57651002 3238261 2557013..2557321 1 NC_002951.2 hypothetical protein 2557321 3238261 SACOL2503 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187298.1 2557013 D 93062 CDS YP_187299.1 57651003 3238262 complement(2557643..2558836) 1 NC_002951.2 identified by match to protein family HMM PF07690; permease 2558836 3238262 SACOL2504 Staphylococcus aureus subsp. aureus COL permease YP_187299.1 2557643 R 93062 CDS YP_187300.1 57651004 3238095 complement(2559220..2562951) 1 NC_002951.2 identified by match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM PF07501; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; cell wall surface anchor family protein 2562951 3238095 SACOL2505 Staphylococcus aureus subsp. aureus COL cell wall surface anchor family protein YP_187300.1 2559220 R 93062 CDS YP_187301.1 57651005 3238096 complement(2563256..2563612) 1 NC_002951.2 identified by match to protein family HMM TIGR01889; accessory regulator T 2563612 sarT 3238096 sarT Staphylococcus aureus subsp. aureus COL accessory regulator T YP_187301.1 2563256 R 93062 CDS YP_187302.1 57651006 3238097 2563936..2564679 1 NC_002951.2 identified by similarity to OMNI:SA2507; match to protein family HMM TIGR01889; accessory regulator U 2564679 sarU 3238097 sarU Staphylococcus aureus subsp. aureus COL accessory regulator U YP_187302.1 2563936 D 93062 CDS YP_187303.1 57651007 3238061 complement(2564890..2565756) 1 NC_002951.2 identified by similarity to EGAD:16704; match to protein family HMM PF00483; match to protein family HMM TIGR01099; UTP-glucose-1-phosphate uridylyltransferase 2565756 galU 3238061 galU Staphylococcus aureus subsp. aureus COL UTP-glucose-1-phosphate uridylyltransferase YP_187303.1 2564890 R 93062 CDS YP_187304.1 57651008 3238062 complement(2565936..2568758) 1 NC_002951.2 identified by match to protein family HMM PF00746; match to protein family HMM PF02986; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; fibronectin binding protein B 2568758 fnbB 3238062 fnbB Staphylococcus aureus subsp. aureus COL fibronectin binding protein B YP_187304.1 2565936 R 93062 CDS YP_187305.1 57651009 3238063 complement(2568919..2569041) 1 NC_002951.2 hypothetical protein 2569041 3238063 SACOL2510 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187305.1 2568919 R 93062 CDS YP_187306.1 57651010 3238064 complement(2569440..2572496) 1 NC_002951.2 identified by similarity to SP:P14738; match to protein family HMM PF00746; match to protein family HMM PF02986; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; fibronectin-binding protein A 2572496 fnbA 3238064 fnbA Staphylococcus aureus subsp. aureus COL fibronectin-binding protein A YP_187306.1 2569440 R 93062 CDS YP_187307.1 57651011 3238113 complement(2572738..2572932) 1 NC_002951.2 hypothetical protein 2572932 3238113 SACOL2513 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187307.1 2572738 R 93062 CDS YP_187308.1 57651012 3238114 complement(2572964..2574322) 1 NC_002951.2 identified by similarity to EGAD:19179; match to protein family HMM PF02447; match to protein family HMM TIGR00791; gluconate transporter, permease 2574322 gntP 3238114 gntP Staphylococcus aureus subsp. aureus COL gluconate transporter, permease YP_187308.1 2572964 R 93062 CDS YP_187309.1 57651013 3238115 complement(2574439..2575992) 1 NC_002951.2 identified by similarity to EGAD:22614; match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01314; gluconokinase 2575992 gntK 3238115 gntK Staphylococcus aureus subsp. aureus COL gluconokinase YP_187309.1 2574439 R 93062 CDS YP_187310.1 57651014 3238291 complement(2576016..2576696) 1 NC_002951.2 identified by similarity to EGAD:17516; match to protein family HMM PF00392; gluconate operon transcriptional repressor 2576696 gntR 3238291 gntR Staphylococcus aureus subsp. aureus COL gluconate operon transcriptional repressor YP_187310.1 2576016 R 93062 CDS YP_187311.1 57651015 3238292 complement(2576850..2577614) 1 NC_002951.2 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 2577614 3238292 SACOL2517 Staphylococcus aureus subsp. aureus COL MerR family transcriptional regulator YP_187311.1 2576850 R 93062 CDS YP_187312.1 57651016 3238293 complement(2577779..2578471) 1 NC_002951.2 identified by similarity to EGAD:14115; match to protein family HMM PF04607; hypothetical protein 2578471 3238293 SACOL2518 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187312.1 2577779 R 93062 CDS YP_187313.1 57651017 3238217 complement(2578702..2579190) 1 NC_002951.2 hypothetical protein 2579190 3238217 SACOL2519 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187313.1 2578702 R 93062 CDS YP_187314.1 57651018 3238218 complement(2579257..2581149) 1 NC_002951.2 identified by match to protein family HMM PF05976; hypothetical protein 2581149 3238218 SACOL2520 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187314.1 2579257 R 93062 CDS YP_187315.1 57651019 3238219 complement(2581558..2582835) 1 NC_002951.2 identified by match to protein family HMM PF07690; transporter 2582835 3238219 SACOL2521 Staphylococcus aureus subsp. aureus COL transporter YP_187315.1 2581558 R 93062 CDS YP_187316.1 57651020 3238220 2583382..2583993 1 NC_002951.2 identified by match to protein family HMM PF00597; DedA family protein 2583993 3238220 SACOL2522 Staphylococcus aureus subsp. aureus COL DedA family protein YP_187316.1 2583382 D 93062 CDS YP_187317.1 57651021 3238187 complement(2584090..2585253) 1 NC_002951.2 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; drug transporter 2585253 3238187 SACOL2523 Staphylococcus aureus subsp. aureus COL drug transporter YP_187317.1 2584090 R 93062 CDS YP_187318.1 57651022 3238188 complement(2585246..2585710) 1 NC_002951.2 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 2585710 3238188 SACOL2524 Staphylococcus aureus subsp. aureus COL MarR family transcriptional regulator YP_187318.1 2585246 R 93062 CDS YP_187319.1 57651023 3238189 2586138..2586833 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2586833 3238189 SACOL2525 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_187319.1 2586138 D 93062 CDS YP_187320.1 57651024 3238402 2587978..2589942 1 NC_002951.2 identified by similarity to EGAD:37656; match to protein family HMM PF06874; fructose-1,6-bisphosphatase 2589942 3238402 SACOL2527 Staphylococcus aureus subsp. aureus COL fructose-1,6-bisphosphatase YP_187320.1 2587978 D 93062 CDS YP_187321.1 57651025 3238403 2590286..2591365 1 NC_002951.2 hypothetical protein 2591365 3238403 SACOL2528 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187321.1 2590286 D 93062 CDS YP_187322.1 57651026 3238404 complement(2591470..2592063) 1 NC_002951.2 phospholipase/carboxylesterase 2592063 3238404 SACOL2529 Staphylococcus aureus subsp. aureus COL phospholipase/carboxylesterase YP_187322.1 2591470 R 93062 CDS YP_187323.1 57651027 3238146 complement(2592085..2593053) 1 NC_002951.2 identified by similarity to GP:10174794; match to protein family HMM PF00903; hypothetical protein 2593053 3238146 SACOL2530 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187323.1 2592085 R 93062 CDS YP_187324.1 57651028 3238147 complement(2593131..2593565) 1 NC_002951.2 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 2593565 3238147 SACOL2531 Staphylococcus aureus subsp. aureus COL MarR family transcriptional regulator YP_187324.1 2593131 R 93062 CDS YP_187325.1 57651029 3238148 2593792..2594076 1 NC_002951.2 acetyltransferase 2594076 3238148 SACOL2532 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_187325.1 2593792 D 93062 CDS YP_187326.1 57651030 3238240 2594247..2595053 1 NC_002951.2 identified by match to protein family HMM PF00903; glyoxalase 2595053 3238240 SACOL2533 Staphylococcus aureus subsp. aureus COL glyoxalase YP_187326.1 2594247 D 93062 CDS YP_187327.1 57651031 3238241 complement(2595173..2595844) 1 NC_002951.2 identified by match to protein family HMM PF00881; NAD(P)H-flavin oxidoreductase 2595844 frp 3238241 frp Staphylococcus aureus subsp. aureus COL NAD(P)H-flavin oxidoreductase YP_187327.1 2595173 R 93062 CDS YP_187328.1 57651032 3238242 2596114..2597106 1 NC_002951.2 catalyzes the formation of pyruvate from lactate; D-lactate dehydrogenase 2597106 3238242 SACOL2535 Staphylococcus aureus subsp. aureus COL D-lactate dehydrogenase YP_187328.1 2596114 D 93062 CDS YP_187329.1 57651033 3238243 complement(2597355..2598155) 1 NC_002951.2 identified by match to protein family HMM TIGR00099; match to protein family HMM TIGR01484; HAD superfamily hydrolase 2598155 3238243 SACOL2536 Staphylococcus aureus subsp. aureus COL HAD superfamily hydrolase YP_187329.1 2597355 R 93062 CDS YP_187330.1 57651034 3238305 2598476..2599111 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2599111 3238305 SACOL2537 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_187330.1 2598476 D 93062 CDS YP_187331.1 57651035 3238306 2599117..2599848 1 NC_002951.2 hypothetical protein 2599848 3238306 SACOL2538 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187331.1 2599117 D 93062 CDS YP_187332.1 57651036 3238307 complement(2600008..2600628) 1 NC_002951.2 identified by similarity to GP:5726436; match to protein family HMM PF04203; match to protein family HMM TIGR01076; sortase 2600628 srtA 3238307 srtA Staphylococcus aureus subsp. aureus COL sortase YP_187332.1 2600008 R 93062 CDS YP_187333.1 57651037 3238678 2600822..2601313 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 2601313 3238678 SACOL2541 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_187333.1 2600822 D 93062 CDS YP_187334.1 57651038 3238679 complement(2601751..2601921) 1 NC_002951.2 hypothetical protein 2601921 3238679 SACOL2542 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187334.1 2601751 R 93062 CDS YP_187335.1 57651039 3238680 complement(2601983..2602081) 1 NC_002951.2 hypothetical protein 2602081 3238680 SACOL2543 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187335.1 2601983 R 93062 CDS YP_187336.1 57651040 3238681 complement(2602100..2602999) 1 NC_002951.2 identified by similarity to EGAD:154938; match to protein family HMM PF03313; match to protein family HMM TIGR00718; L-serine dehydratase, iron-sulfur-dependent subunit alpha 2602999 sdaAA 3238681 sdaAA Staphylococcus aureus subsp. aureus COL L-serine dehydratase, iron-sulfur-dependent subunit alpha YP_187336.1 2602100 R 93062 CDS YP_187337.1 57651041 3238286 complement(2603013..2603693) 1 NC_002951.2 identified by similarity to SP:P33074; match to protein family HMM PF03315; match to protein family HMM TIGR00719; L-serine dehydratase, iron-sulfur-dependent subunit beta 2603693 sdaAB 3238286 sdaAB Staphylococcus aureus subsp. aureus COL L-serine dehydratase, iron-sulfur-dependent subunit beta YP_187337.1 2603013 R 93062 CDS YP_187338.1 57651042 3238287 complement(2603696..2604739) 1 NC_002951.2 identified by similarity to EGAD:33437; perfringolysin O regulator protein 2604739 3238287 SACOL2546 Staphylococcus aureus subsp. aureus COL perfringolysin O regulator protein YP_187338.1 2603696 R 93062 CDS YP_187339.1 57651043 3238288 2605291..2605494 1 NC_002951.2 hypothetical protein 2605494 3238288 SACOL2547 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187339.1 2605291 D 93062 CDS YP_187340.1 57651044 3238308 2605650..2606612 1 NC_002951.2 identified by similarity to GP:10173339; match to protein family HMM PF00892; hypothetical protein 2606612 3238308 SACOL2548 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187340.1 2605650 D 93062 CDS YP_187341.1 57651045 3238309 complement(2606694..2607662) 1 NC_002951.2 identified by similarity to EGAD:16024; hypothetical protein 2607662 3238309 SACOL2549 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187341.1 2606694 R 93062 CDS YP_187342.1 57651046 3236046 complement(2607795..2608139) 1 NC_002951.2 hypothetical protein 2608139 3236046 SACOL2550 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187342.1 2607795 R 93062 CDS YP_187343.1 57651047 3238310 complement(2608181..2608591) 1 NC_002951.2 identified by similarity to OMNI:VC1938; hypothetical protein 2608591 3238310 SACOL2551 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187343.1 2608181 R 93062 CDS YP_187344.1 57651048 3238311 complement(2608971..2611037) 1 NC_002951.2 identified by match to protein family HMM PF00358; match to protein family HMM PF00367; match to protein family HMM PF02378; match to protein family HMM TIGR00826; match to protein family HMM TIGR00830; match to protein family HMM TIGR02002; PTS system, IIABC components 2611037 3238311 SACOL2552 Staphylococcus aureus subsp. aureus COL PTS system, IIABC components YP_187344.1 2608971 R 93062 CDS YP_187345.1 57651049 3238065 complement(2611338..2613077) 1 NC_002951.2 catalyzes the formation of acetyl phosphate from pyruvate; pyruvate oxidase 2613077 3238065 SACOL2553 Staphylococcus aureus subsp. aureus COL pyruvate oxidase YP_187345.1 2611338 R 93062 CDS YP_187346.1 57651050 3238066 complement(2613124..2613813) 1 NC_002951.2 identified by match to protein family HMM PF04172; hypothetical protein 2613813 3238066 SACOL2554 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187346.1 2613124 R 93062 CDS YP_187347.1 57651051 3238067 complement(2613806..2614201) 1 NC_002951.2 identified by match to protein family HMM PF03788; LrgA family protein 2614201 3238067 SACOL2554.1 Staphylococcus aureus subsp. aureus COL LrgA family protein YP_187347.1 2613806 R 93062 CDS YP_187348.1 57651052 3238206 complement(2614414..2615298) 1 NC_002951.2 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 2615298 3238206 SACOL2555 Staphylococcus aureus subsp. aureus COL LysR family transcriptional regulator YP_187348.1 2614414 R 93062 CDS YP_187349.1 57651053 3238207 2615459..2615677 1 NC_002951.2 identified by similarity to GB:AAO05749.1; hypothetical protein 2615677 3238207 SACOL2556 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187349.1 2615459 D 93062 CDS YP_187350.1 57651054 3238208 2616066..2616497 1 NC_002951.2 identified by match to protein family HMM PF05257; hypothetical protein 2616497 3238208 SACOL2557 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187350.1 2616066 D 93062 CDS YP_187351.1 57651055 3238209 complement(2617257..2617514) 1 NC_002951.2 hypothetical protein 2617514 3238209 SACOL2559 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187351.1 2617257 R 93062 CDS YP_187352.1 57651056 3238671 complement(2618093..2619370) 1 NC_002951.2 identified by similarity to EGAD:9852; match to protein family HMM PF00368; match to protein family HMM TIGR00532; hydroxymethylglutaryl-CoA reductase, degradative 2619370 3238671 SACOL2560 Staphylococcus aureus subsp. aureus COL hydroxymethylglutaryl-CoA reductase, degradative YP_187352.1 2618093 R 93062 CDS YP_187353.1 57651057 3238672 2619624..2620790 1 NC_002951.2 identified by similarity to GP:9937361; match to protein family HMM PF01154; match to protein family HMM TIGR01835; hydroxymethylglutaryl-CoA synthase 2620790 3238672 SACOL2561 Staphylococcus aureus subsp. aureus COL hydroxymethylglutaryl-CoA synthase YP_187353.1 2619624 D 93062 CDS YP_187354.1 57651058 3238673 complement(2620960..2621481) 1 NC_002951.2 identified by similarity to EGAD:29038; match to protein family HMM PF01035; match to protein family HMM PF02870; match to protein family HMM TIGR00589; methylated-DNA--protein-cysteine methyltransferase 2621481 ogt 3238673 ogt Staphylococcus aureus subsp. aureus COL methylated-DNA--protein-cysteine methyltransferase YP_187354.1 2620960 R 93062 CDS YP_187355.1 57651059 3238674 2621890..2623995 1 NC_002951.2 identified by match to protein family HMM PF00004; match to protein family HMM PF02151; ATP-dependent Clp protease 2623995 3238674 SACOL2563 Staphylococcus aureus subsp. aureus COL ATP-dependent Clp protease YP_187355.1 2621890 D 93062 CDS YP_187356.1 57652286 3237233 complement(2624247..2626241) 1 NC_002951.2 identified by similarity to EGAD:7439; match to protein family HMM PF02421; match to protein family HMM PF07664; match to protein family HMM PF07670; match to protein family HMM TIGR00231; match to protein family HMM TIGR00437; ferrous iron transport protein B 2626241 feoB 3237233 feoB Staphylococcus aureus subsp. aureus COL ferrous iron transport protein B YP_187356.1 2624247 R 93062 CDS YP_187357.1 57652287 3237219 complement(2626253..2626480) 1 NC_002951.2 identified by match to protein family HMM PF04023; FeoA domain-containing protein 2626480 3237219 SACOL2565 Staphylococcus aureus subsp. aureus COL FeoA domain-containing protein YP_187357.1 2626253 R 93062 CDS YP_187358.1 57652288 3237220 complement(2626696..2629185) 1 NC_002951.2 identified by match to protein family HMM PF03176; MmpL efflux pump 2629185 3237220 SACOL2566 Staphylococcus aureus subsp. aureus COL MmpL efflux pump YP_187358.1 2626696 R 93062 CDS YP_187359.1 57652289 3237221 2629393..2629878 1 NC_002951.2 hypothetical protein 2629878 3237221 SACOL2567 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187359.1 2629393 D 93062 CDS YP_187360.1 57652290 3237222 complement(2629955..2630122) 1 NC_002951.2 hypothetical protein 2630122 3237222 SACOL2568 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187360.1 2629955 R 93062 CDS YP_187361.1 57652291 3237223 complement(2630234..2631778) 1 NC_002951.2 catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate; 1-pyrroline-5-carboxylate dehydrogenase 2631778 3237223 SACOL2569 Staphylococcus aureus subsp. aureus COL 1-pyrroline-5-carboxylate dehydrogenase YP_187361.1 2630234 R 93062 CDS YP_187362.1 57652292 3237224 complement(2631968..2632567) 1 NC_002951.2 identified by similarity to EGAD:12452; match to protein family HMM PF00132; galactoside O-acetyltransferase 2632567 3237224 SACOL2570 Staphylococcus aureus subsp. aureus COL galactoside O-acetyltransferase YP_187362.1 2631968 R 93062 CDS YP_187363.1 57652293 3237225 2632806..2632997 1 NC_002951.2 identified by similarity to GB:AAO05760.1; hypothetical protein 2632997 3237225 SACOL2571 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187363.1 2632806 D 93062 CDS YP_187364.1 57652294 3237226 2633237..2635645 1 NC_002951.2 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; copper-translocating P-type ATPase 2635645 3237226 SACOL2572 Staphylococcus aureus subsp. aureus COL copper-translocating P-type ATPase YP_187364.1 2633237 D 93062 CDS YP_187365.1 57652295 3237212 2635936..2636142 1 NC_002951.2 identified by match to protein family HMM PF00403; match to protein family HMM TIGR00003; copper ion binding protein 2636142 3237212 SACOL2573 Staphylococcus aureus subsp. aureus COL copper ion binding protein YP_187365.1 2635936 D 93062 CDS YP_187366.1 57652296 3237213 complement(2636232..2637230) 1 NC_002951.2 catalyzes the formation of pyruvate from lactate; D-lactate dehydrogenase 2637230 3237213 SACOL2574 Staphylococcus aureus subsp. aureus COL D-lactate dehydrogenase YP_187366.1 2636232 R 93062 CDS YP_187367.1 57652297 3237214 complement(2637253..2638407) 1 NC_002951.2 identified by match to protein family HMM PF00155; aminotransferase, class I 2638407 3237214 SACOL2575 Staphylococcus aureus subsp. aureus COL aminotransferase, class I YP_187367.1 2637253 R 93062 CDS YP_187368.1 57652298 3237215 complement(2638834..2640342) 1 NC_002951.2 identified by match to protein family HMM PF01593; squalene synthase 2640342 crtN 3237215 crtN Staphylococcus aureus subsp. aureus COL squalene synthase YP_187368.1 2638834 R 93062 CDS YP_187369.1 57652299 3237216 complement(2640354..2641217) 1 NC_002951.2 identified by similarity to GP:2224841; match to protein family HMM PF00494; dehydrosqualene synthase 2641217 crtM 3237216 crtM Staphylococcus aureus subsp. aureus COL dehydrosqualene synthase YP_187369.1 2640354 R 93062 CDS YP_187370.1 57652300 3237217 complement(2641254..2642390) 1 NC_002951.2 identified by match to protein family HMM PF00535; glycosyl transferase, group 2 family protein 2642390 3237217 SACOL2578 Staphylococcus aureus subsp. aureus COL glycosyl transferase, group 2 family protein YP_187370.1 2641254 R 93062 CDS YP_187371.1 57652301 3237218 complement(2642387..2643880) 1 NC_002951.2 identified by similarity to EGAD:16690; match to protein family HMM PF01593; phytoene dehydrogenase 2643880 3237218 SACOL2579 Staphylococcus aureus subsp. aureus COL phytoene dehydrogenase YP_187371.1 2642387 R 93062 CDS YP_187372.1 57652302 3237204 complement(2643873..2644361) 1 NC_002951.2 hypothetical protein 2644361 3237204 SACOL2580 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187372.1 2643873 R 93062 CDS YP_187373.1 57652303 3237205 complement(2644536..2645303) 1 NC_002951.2 identified by match to protein family HMM PF05257; staphyloxanthin biosynthesis protein 2645303 3237205 SACOL2581 Staphylococcus aureus subsp. aureus COL staphyloxanthin biosynthesis protein YP_187373.1 2644536 R 93062 CDS YP_187374.1 57652304 3237206 complement(2645664..2647475) 1 NC_002951.2 identified by match to protein family HMM PF01757; hypothetical protein 2647475 3237206 SACOL2582 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187374.1 2645664 R 93062 CDS YP_187375.1 57652305 3237207 complement(2647987..2648475) 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 2648475 3237207 SACOL2583 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_187375.1 2647987 R 93062 CDS YP_187376.1 57652306 3237208 complement(2648751..2649452) 1 NC_002951.2 identified by match to protein family HMM PF06737; immunodominant antigen A 2649452 isaA 3237208 isaA Staphylococcus aureus subsp. aureus COL immunodominant antigen A YP_187376.1 2648751 R 93062 CDS YP_187377.1 57652307 3237209 complement(2650060..2651115) 1 NC_002951.2 hypothetical protein 2651115 3237209 SACOL2585 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187377.1 2650060 R 93062 CDS YP_187378.1 57652308 3237210 2651492..2652094 1 NC_002951.2 hypothetical protein 2652094 3237210 SACOL2587 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187378.1 2651492 D 93062 CDS YP_187379.1 57652309 3237211 2652292..2652792 1 NC_002951.2 hypothetical protein 2652792 3237211 SACOL2588 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187379.1 2652292 D 93062 CDS YP_187380.1 57652310 3237196 2653012..2653242 1 NC_002951.2 identified by match to protein family HMM PF05979; hypothetical protein 2653242 3237196 SACOL2589 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187380.1 2653012 D 93062 CDS YP_187381.1 57652311 3237197 complement(2653392..2653769) 1 NC_002951.2 identified by match to protein family HMM PF00903; glyoxalase 2653769 3237197 SACOL2590 Staphylococcus aureus subsp. aureus COL glyoxalase YP_187381.1 2653392 R 93062 CDS YP_187382.1 57652312 3237198 complement(2653786..2654607) 1 NC_002951.2 identified by similarity to EGAD:19015; hypothetical protein 2654607 3237198 SACOL2591 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187382.1 2653786 R 93062 CDS YP_187383.1 57652313 3237199 complement(2654627..2654926) 1 NC_002951.2 hypothetical protein 2654926 3237199 SACOL2592 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187383.1 2654627 R 93062 CDS YP_187384.1 57652314 3237200 2655057..2655614 1 NC_002951.2 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 2655614 3237200 SACOL2593 Staphylococcus aureus subsp. aureus COL TetR family transcriptional regulator YP_187384.1 2655057 D 93062 CDS YP_187385.1 57652315 3237201 2655607..2656311 1 NC_002951.2 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase 2656311 3237201 SACOL2594 Staphylococcus aureus subsp. aureus COL short chain dehydrogenase/reductase oxidoreductase YP_187385.1 2655607 D 93062 CDS YP_187386.1 57652316 3237202 2656321..2656428 1 NC_002951.2 hypothetical protein 2656428 3237202 SACOL2595 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187386.1 2656321 D 93062 CDS YP_187387.1 57652317 3237203 2656409..2657419 1 NC_002951.2 identified by match to protein family HMM PF04909; hypothetical protein 2657419 3237203 SACOL2596 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187387.1 2656409 D 93062 CDS YP_187388.1 57652318 3237184 2657439..2658269 1 NC_002951.2 identified by match to protein family HMM PF00561; alpha/beta fold family hydrolase 2658269 3237184 SACOL2597 Staphylococcus aureus subsp. aureus COL alpha/beta fold family hydrolase YP_187388.1 2657439 D 93062 CDS YP_187389.1 57652319 3237185 complement(2658416..2659306) 1 NC_002951.2 identified by similarity to EGAD:156097; match to protein family HMM PF02492; match to protein family HMM PF07683; cobalamin synthesis protein 2659306 3237185 SACOL2598 Staphylococcus aureus subsp. aureus COL cobalamin synthesis protein YP_187389.1 2658416 R 93062 CDS YP_187390.1 57652320 3237186 complement(2659404..2660723) 1 NC_002951.2 identified by match to protein family HMM PF07670; hypothetical protein 2660723 3237186 SACOL2599 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187390.1 2659404 R 93062 CDS YP_187391.1 57652321 3237187 complement(2660738..2661844) 1 NC_002951.2 hypothetical protein 2661844 3237187 SACOL2600 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187391.1 2660738 R 93062 CDS YP_187392.1 57652322 3237188 complement(2662178..2662474) 1 NC_002951.2 identified by similarity to GP:10173595; hypothetical protein 2662474 3237188 SACOL2601 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187392.1 2662178 R 93062 CDS YP_187393.1 57652323 3237189 complement(2662462..2662830) 1 NC_002951.2 hypothetical protein 2662830 3237189 SACOL2602 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187393.1 2662462 R 93062 CDS YP_187394.1 57652324 3237190 complement(2662845..2663123) 1 NC_002951.2 hypothetical protein 2663123 3237190 SACOL2603 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187394.1 2662845 R 93062 CDS YP_187395.1 57652325 3237191 complement(2663465..2664274) 1 NC_002951.2 identified by similarity to GP:22295547; match to protein family HMM PF03881; hypothetical protein 2664274 3237191 SACOL2605 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187395.1 2663465 R 93062 CDS YP_187396.1 57652326 3237177 2664549..2665613 1 NC_002951.2 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 2665613 pyrD 3237177 pyrD Staphylococcus aureus subsp. aureus COL dihydroorotate dehydrogenase 2 YP_187396.1 2664549 D 93062 CDS YP_187397.1 57652327 3237178 2665768..2666043 1 NC_002951.2 hypothetical protein 2666043 3237178 SACOL2607 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187397.1 2665768 D 93062 CDS YP_187398.1 57652328 3237179 complement(2666229..2666951) 1 NC_002951.2 identified by match to protein family HMM PF02677; hypothetical protein 2666951 3237179 SACOL2608 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187398.1 2666229 R 93062 CDS YP_187399.1 57652329 3237180 2667305..2667754 1 NC_002951.2 hypothetical protein 2667754 3237180 SACOL2609 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187399.1 2667305 D 93062 CDS YP_187400.1 57652330 3237181 complement(2667835..2668422) 1 NC_002951.2 TetR family transcriptional regulator 2668422 3237181 SACOL2610 Staphylococcus aureus subsp. aureus COL TetR family transcriptional regulator YP_187400.1 2667835 R 93062 CDS YP_187401.1 57652331 3237182 2668555..2670237 1 NC_002951.2 identified by match to protein family HMM PF02129; match to protein family HMM TIGR00976; CocE/NonD family hydrolase 2670237 3237182 SACOL2612 Staphylococcus aureus subsp. aureus COL CocE/NonD family hydrolase YP_187401.1 2668555 D 93062 CDS YP_187402.1 57652332 3237183 complement(2670366..2670749) 1 NC_002951.2 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 2670749 panD 3237183 panD Staphylococcus aureus subsp. aureus COL aspartate alpha-decarboxylase YP_187402.1 2670366 R 93062 CDS YP_187403.1 57652333 3237170 complement(2670751..2671602) 1 NC_002951.2 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 2671602 panC 3237170 panC Staphylococcus aureus subsp. aureus COL pantoate--beta-alanine ligase YP_187403.1 2670751 R 93062 CDS YP_187404.1 57652334 3237171 complement(2671595..2672413) 1 NC_002951.2 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 2672413 panB 3237171 panB Staphylococcus aureus subsp. aureus COL 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_187404.1 2671595 R 93062 CDS YP_187405.1 57652335 3237172 2672486..2673346 1 NC_002951.2 catalyzes the formation of 2-dehydropantoate from (R)-pantoate; 2-dehydropantoate 2-reductase 2673346 3237172 SACOL2616 Staphylococcus aureus subsp. aureus COL 2-dehydropantoate 2-reductase YP_187405.1 2672486 D 93062 CDS YP_187406.1 57652336 3237173 complement(2673432..2674136) 1 NC_002951.2 identified by similarity to EGAD:8473; match to protein family HMM PF03306; match to protein family HMM TIGR01252; alpha-acetolactate decarboxylase 2674136 budA2 3237173 budA2 Staphylococcus aureus subsp. aureus COL alpha-acetolactate decarboxylase YP_187406.1 2673432 R 93062 CDS YP_187407.1 57652337 3237174 complement(2674414..2675373) 1 NC_002951.2 identified by similarity to EGAD:16887; match to protein family HMM PF00056; match to protein family HMM PF02866; match to protein family HMM TIGR01771; L-lactate dehydrogenase 2675373 ldh2 3237174 ldh2 Staphylococcus aureus subsp. aureus COL L-lactate dehydrogenase YP_187407.1 2674414 R 93062 CDS YP_187408.1 57652338 3237175 2676060..2677508 1 NC_002951.2 identified by match to protein family HMM PF00324; amino acid permease 2677508 3237175 SACOL2619 Staphylococcus aureus subsp. aureus COL amino acid permease YP_187408.1 2676060 D 93062 CDS YP_187409.1 57652339 3237176 complement(2677589..2678926) 1 NC_002951.2 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 2678926 3237176 SACOL2620 Staphylococcus aureus subsp. aureus COL 4-aminobutyrate aminotransferase YP_187409.1 2677589 R 93062 CDS YP_187410.1 57652340 3237072 2679184..2679600 1 NC_002951.2 hypothetical protein 2679600 3237072 SACOL2621 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187410.1 2679184 D 93062 CDS YP_187411.1 57652341 3237073 2679723..2680613 1 NC_002951.2 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis; fructose-1,6-bisphosphate aldolase 2680613 fdaB 3237073 fdaB Staphylococcus aureus subsp. aureus COL fructose-1,6-bisphosphate aldolase YP_187411.1 2679723 D 93062 CDS YP_187412.1 57652342 3237074 complement(2680806..2682302) 1 NC_002951.2 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 2682302 mqo2 3237074 mqo2 Staphylococcus aureus subsp. aureus COL malate:quinone oxidoreductase YP_187412.1 2680806 R 93062 CDS YP_187413.1 57652343 3237075 complement(2682987..2684585) 1 NC_002951.2 identified by similarity to EGAD:18603; match to protein family HMM PF00501; acetyl-CoA synthetase 2684585 3237075 SACOL2624 Staphylococcus aureus subsp. aureus COL acetyl-CoA synthetase YP_187413.1 2682987 R 93062 CDS YP_187414.1 57652344 3237076 complement(2684779..2685222) 1 NC_002951.2 identified by match to protein family HMM PF03992; hypothetical protein 2685222 3237076 SACOL2625 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187414.1 2684779 R 93062 CDS YP_187415.1 57652345 3237077 complement(2685503..2685715) 1 NC_002951.2 identified by similarity to GB:AAO05805.1; match to protein family HMM PF06855; hypothetical protein 2685715 3237077 SACOL2626 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187415.1 2685503 R 93062 CDS YP_187416.1 57652346 3237169 complement(2685993..2687702) 1 NC_002951.2 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 2687702 betA 3237169 betA Staphylococcus aureus subsp. aureus COL choline dehydrogenase YP_187416.1 2685993 R 93062 CDS YP_187417.1 57652347 3237065 complement(2687963..2689453) 1 NC_002951.2 identified by similarity to EGAD:97843; match to protein family HMM PF00171; match to protein family HMM TIGR01804; betaine aldehyde dehydrogenase 2689453 betB 3237065 betB Staphylococcus aureus subsp. aureus COL betaine aldehyde dehydrogenase YP_187417.1 2687963 R 93062 CDS YP_187418.1 57652348 3237066 2689522..2689617 1 NC_002951.2 hypothetical protein 2689617 3237066 SACOL2629 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187418.1 2689522 D 93062 CDS YP_187419.1 57652349 3237067 2689706..2690269 1 NC_002951.2 identified by similarity to GP:4574119; hypothetical protein 2690269 3237067 SACOL2630 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187419.1 2689706 D 93062 CDS YP_187420.1 57652350 3237068 complement(2690457..2691143) 1 NC_002951.2 hypothetical protein 2691143 3237068 SACOL2631 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187420.1 2690457 R 93062 CDS YP_187421.1 57652351 3237069 complement(2691407..2693029) 1 NC_002951.2 identified by similarity to EGAD:45763; match to protein family HMM PF02028; match to protein family HMM TIGR00842; BCCT family osmoprotectant transporter 2693029 cudT 3237069 cudT Staphylococcus aureus subsp. aureus COL BCCT family osmoprotectant transporter YP_187421.1 2691407 R 93062 CDS YP_187422.1 57652352 3237070 complement(2693548..2694084) 1 NC_002951.2 identified by similarity to GP:4098082; anaerobic ribonucleoside-triphosphate reductase activating protein 2694084 nrdG 3237070 nrdG Staphylococcus aureus subsp. aureus COL anaerobic ribonucleoside-triphosphate reductase activating protein YP_187422.1 2693548 R 93062 CDS YP_187423.1 57652353 3237071 complement(2694081..2695931) 1 NC_002951.2 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 2695931 nrdD 3237071 nrdD Staphylococcus aureus subsp. aureus COL anaerobic ribonucleoside triphosphate reductase YP_187423.1 2694081 R 93062 CDS YP_187424.1 57652354 3237057 complement(2696178..2697548) 1 NC_002951.2 identified by match to protein family HMM PF03600; match to protein family HMM TIGR00784; citrate transporter, permease 2697548 3237057 SACOL2636 Staphylococcus aureus subsp. aureus COL citrate transporter, permease YP_187424.1 2696178 R 93062 CDS YP_187425.1 57652355 3237058 complement(2697870..2697965) 1 NC_002951.2 hypothetical protein 2697965 3237058 SACOL2637 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187425.1 2697870 R 93062 CDS YP_187426.1 57652356 3237059 complement(2698041..2698646) 1 NC_002951.2 catalyzes the formation of siroheme from precorrin-2; precorrin-2 dehydrogenase 2698646 3237059 SACOL2638 Staphylococcus aureus subsp. aureus COL precorrin-2 dehydrogenase YP_187426.1 2698041 R 93062 CDS YP_187427.1 57652357 3237060 complement(2698709..2700589) 1 NC_002951.2 identified by similarity to SP:P38038; match to protein family HMM PF00175; match to protein family HMM PF00258; match to protein family HMM PF00667; match to protein family HMM TIGR01931; sulfite reductase (NADPH) flavoprotein alpha-component 2700589 cysJ 3237060 cysJ Staphylococcus aureus subsp. aureus COL sulfite reductase (NADPH) flavoprotein alpha-component YP_187427.1 2698709 R 93062 CDS YP_187428.1 57652358 3237061 2700784..2700876 1 NC_002951.2 hypothetical protein 2700876 3237061 SACOL2640 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187428.1 2700784 D 93062 CDS YP_187429.1 57652359 3237062 complement(2700984..2701481) 1 NC_002951.2 identified by similarity to EGAD:45646; match to protein family HMM PF00255; glutathione peroxidase 2701481 gpxA2 3237062 gpxA2 Staphylococcus aureus subsp. aureus COL glutathione peroxidase YP_187429.1 2700984 R 93062 CDS YP_187430.1 57652360 3237063 complement(2702176..2702289) 1 NC_002951.2 hypothetical protein 2702289 3237063 SACOL2642 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187430.1 2702176 R 93062 CDS YP_187431.1 57652361 3237064 complement(2702905..2704905) 1 NC_002951.2 identified by match to protein family HMM PF02687; ABC transporter permease 2704905 3237064 SACOL2643 Staphylococcus aureus subsp. aureus COL ABC transporter permease YP_187431.1 2702905 R 93062 CDS YP_187432.1 57652362 3237047 complement(2704902..2705666) 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2705666 3237047 SACOL2644 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_187432.1 2704902 R 93062 CDS YP_187433.1 57652363 3237048 complement(2705765..2706652) 1 NC_002951.2 identified by match to protein family HMM PF02518; nisin susceptibility-associated sensor histidine kinase 2706652 nsaS 3237048 nsaS Staphylococcus aureus subsp. aureus COL nisin susceptibility-associated sensor histidine kinase YP_187433.1 2705765 R 93062 CDS YP_187434.1 57652364 3237049 complement(2706663..2707328) 1 NC_002951.2 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 2707328 3237049 SACOL2646 Staphylococcus aureus subsp. aureus COL DNA-binding response regulator YP_187434.1 2706663 R 93062 CDS YP_187435.1 57652365 3237050 complement(2707354..2707554) 1 NC_002951.2 hypothetical protein 2707554 3237050 SACOL2647 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187435.1 2707354 R 93062 CDS YP_187436.1 57652366 3237051 2707752..2709176 1 NC_002951.2 identified by match to protein family HMM PF00245; alkaline phosphatase 2709176 3237051 SACOL2648 Staphylococcus aureus subsp. aureus COL alkaline phosphatase YP_187436.1 2707752 D 93062 CDS YP_187437.1 57652367 3237052 complement(2709236..2709337) 1 NC_002951.2 identified by similarity to GB:AAO05842.1; hypothetical protein 2709337 3237052 SACOL2649 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187437.1 2709236 R 93062 CDS YP_187438.1 57652368 3237053 complement(2709459..2709914) 1 NC_002951.2 transcriptional regulator 2709914 3237053 SACOL2650 Staphylococcus aureus subsp. aureus COL transcriptional regulator YP_187438.1 2709459 R 93062 CDS YP_187439.1 57652369 3237054 complement(2710159..2710920) 1 NC_002951.2 identified by similarity to GP:7453516; similarity to OMNI:NTL01LL1811; match to protein family HMM PF00756; tributyrin esterase EstA 2710920 3237054 SACOL2651 Staphylococcus aureus subsp. aureus COL tributyrin esterase EstA YP_187439.1 2710159 R 93062 CDS YP_187440.1 57652370 3237041 complement(2711036..2713777) 1 NC_002951.2 identified by similarity to GP:3393011; match to protein family HMM PF00746; match to protein family HMM PF04650; match to protein family HMM TIGR01167; match to protein family HMM TIGR01168; clumping factor B 2713777 clfB 3237041 clfB Staphylococcus aureus subsp. aureus COL clumping factor B YP_187440.1 2711036 R 93062 CDS YP_187441.1 57652371 3237042 complement(2714127..2714813) 1 NC_002951.2 identified by similarity to GP:8894540; Crp/FNR family transcriptional regulator 2714813 3237042 SACOL2653 Staphylococcus aureus subsp. aureus COL Crp/FNR family transcriptional regulator YP_187441.1 2714127 R 93062 CDS YP_187442.1 57652372 3237043 complement(2714930..2715871) 1 NC_002951.2 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2715871 arcC2 3237043 arcC2 Staphylococcus aureus subsp. aureus COL carbamate kinase YP_187442.1 2714930 R 93062 CDS YP_187443.1 57652373 3237044 complement(2715888..2717318) 1 NC_002951.2 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00905; arginine/ornithine antiporter 2717318 arcD 3237044 arcD Staphylococcus aureus subsp. aureus COL arginine/ornithine antiporter YP_187443.1 2715888 R 93062 CDS YP_187444.1 57652374 3237045 complement(2717409..2718419) 1 NC_002951.2 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 2718419 arcB2 3237045 arcB2 Staphylococcus aureus subsp. aureus COL ornithine carbamoyltransferase YP_187444.1 2717409 R 93062 CDS YP_187445.1 57652375 3237046 complement(2718452..2719687) 1 NC_002951.2 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 2719687 arcA 3237046 arcA Staphylococcus aureus subsp. aureus COL arginine deiminase YP_187445.1 2718452 R 93062 CDS YP_187446.1 57652376 3237033 complement(2720034..2720483) 1 NC_002951.2 identified by similarity to EGAD:18464; match to protein family HMM PF02863; ArgR family transcriptional regulator 2720483 3237033 SACOL2658 Staphylococcus aureus subsp. aureus COL ArgR family transcriptional regulator YP_187446.1 2720034 R 93062 CDS YP_187447.1 57652377 3237034 complement(2720850..2722379) 1 NC_002951.2 identified by similarity to SP:P81177; match to protein family HMM PF01447; match to protein family HMM PF02868; match to protein family HMM PF03413; match to protein family HMM PF07504; zinc metalloproteinase aureolysin 2722379 aur 3237034 aur Staphylococcus aureus subsp. aureus COL zinc metalloproteinase aureolysin YP_187447.1 2720850 R 93062 CDS YP_187448.1 57652378 3237035 complement(2722803..2723330) 1 NC_002951.2 immunodominant antigen B 2723330 isaB 3237035 isaB Staphylococcus aureus subsp. aureus COL immunodominant antigen B YP_187448.1 2722803 R 93062 CDS YP_187449.1 57652379 3237036 2723588..2724046 1 NC_002951.2 identified by similarity to GB:AAO05863.1; hypothetical protein 2724046 3237036 SACOL2661 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187449.1 2723588 D 93062 CDS YP_187450.1 57652380 3237037 2724286..2726160 1 NC_002951.2 identified by match to protein family HMM PF00359; match to protein family HMM PF00874; BglG family transcriptional antiterminator 2726160 3237037 SACOL2662 Staphylococcus aureus subsp. aureus COL BglG family transcriptional antiterminator YP_187450.1 2724286 D 93062 CDS YP_187451.1 57652381 3237038 2726237..2728189 1 NC_002951.2 identified by match to protein family HMM PF00359; match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR00848; match to protein family HMM TIGR01427; PTS system, fructose-specific IIABC components 2728189 3237038 SACOL2663 Staphylococcus aureus subsp. aureus COL PTS system, fructose-specific IIABC components YP_187451.1 2726237 D 93062 CDS YP_187452.1 57652382 3237039 2728203..2729141 1 NC_002951.2 identified by similarity to EGAD:14340; match to protein family HMM PF01238; match to protein family HMM TIGR00218; mannose-6-phosphate isomerase 2729141 manA2 3237039 manA2 Staphylococcus aureus subsp. aureus COL mannose-6-phosphate isomerase YP_187452.1 2728203 D 93062 CDS YP_187453.1 57652383 3237040 complement(2729253..2732234) 1 NC_002951.2 identified by match to protein family HMM PF01061; phage infection protein 2732234 3237040 SACOL2665 Staphylococcus aureus subsp. aureus COL phage infection protein YP_187453.1 2729253 R 93062 CDS YP_187454.1 57652384 3237025 2732445..2734304 1 NC_002951.2 identified by similarity to EGAD:7341; match to protein family HMM PF01832; match to protein family HMM PF05257; N-acetylmuramoyl-L-alanine amidase 2734304 3237025 SACOL2666 Staphylococcus aureus subsp. aureus COL N-acetylmuramoyl-L-alanine amidase YP_187454.1 2732445 D 93062 CDS YP_187455.1 57652385 3237026 complement(2734571..2735131) 1 NC_002951.2 identified by match to protein family HMM PF00857; isochorismatase 2735131 3237026 SACOL2667 Staphylococcus aureus subsp. aureus COL isochorismatase YP_187455.1 2734571 R 93062 CDS YP_187456.1 57652386 3237027 complement(2735299..2737206) 1 NC_002951.2 LPXTG cell wall surface anchor family protein 2737206 3237027 SACOL2668 Staphylococcus aureus subsp. aureus COL LPXTG cell wall surface anchor family protein YP_187456.1 2735299 R 93062 CDS YP_187457.1 57652387 3237028 complement(2737448..2738806) 1 NC_002951.2 hypothetical protein 2738806 3237028 SACOL2669 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187457.1 2737448 R 93062 CDS YP_187458.1 57652388 3237029 complement(2738799..2740307) 1 NC_002951.2 identified by match to protein family HMM PF00534; glycosyl transferase, group 1 family protein 2740307 3237029 SACOL2670 Staphylococcus aureus subsp. aureus COL glycosyl transferase, group 1 family protein YP_187458.1 2738799 R 93062 CDS YP_187459.1 57652389 3237030 complement(2740325..2742715) 1 NC_002951.2 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins; preprotein translocase subunit SecA 2742715 3237030 SACOL2671 Staphylococcus aureus subsp. aureus COL preprotein translocase subunit SecA YP_187459.1 2740325 R 93062 CDS YP_187460.1 57652390 3237031 complement(2742705..2743664) 1 NC_002951.2 identified by similarity to GB:AAK17000.1; hypothetical protein 2743664 3237031 SACOL2672 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187460.1 2742705 R 93062 CDS YP_187461.1 57652391 3237032 complement(2743642..2745210) 1 NC_002951.2 identified by similarity to GB:AAK16999.1; hypothetical protein 2745210 3237032 SACOL2673 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187461.1 2743642 R 93062 CDS YP_187462.1 57652392 3237018 complement(2745200..2746753) 1 NC_002951.2 identified by similarity to GB:AAK16998.1; accessory secretory protein Asp1 2746753 3237018 SACOL2674 Staphylococcus aureus subsp. aureus COL accessory secretory protein Asp1 YP_187462.1 2745200 R 93062 CDS YP_187463.1 57652393 3237019 complement(2746764..2747975) 1 NC_002951.2 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 2747975 secY 3237019 secY Staphylococcus aureus subsp. aureus COL preprotein translocase subunit SecY YP_187463.1 2746764 R 93062 CDS YP_187464.1 57652394 3237020 complement(2748105..2754890) 1 NC_002951.2 identified by match to protein family HMM PF00746; match to protein family HMM PF05345; match to protein family HMM TIGR01167; LPXTG cell wall surface anchor family protein 2754890 3237020 SACOL2676 Staphylococcus aureus subsp. aureus COL LPXTG cell wall surface anchor family protein YP_187464.1 2748105 R 93062 CDS YP_187465.1 57652395 3237021 complement(2755244..2755354) 1 NC_002951.2 hypothetical protein 2755354 3237021 SACOL2677 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187465.1 2755244 R 93062 CDS YP_187466.1 57652396 3237022 complement(2755435..2756127) 1 NC_002951.2 hypothetical protein 2756127 3237022 SACOL2678 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187466.1 2755435 R 93062 CDS YP_187467.1 57652397 3237023 2756808..2757110 1 NC_002951.2 hypothetical protein 2757110 3237023 SACOL2680 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187467.1 2756808 D 93062 CDS YP_187468.1 57652398 3237024 2757264..2757623 1 NC_002951.2 hypothetical protein 2757623 3237024 SACOL2681 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187468.1 2757264 D 93062 CDS YP_187469.1 57652399 3237011 complement(2757708..2758319) 1 NC_002951.2 hypothetical protein 2758319 3237011 SACOL2682 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187469.1 2757708 R 93062 CDS YP_187470.1 57652400 3237012 complement(2758398..2758874) 1 NC_002951.2 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; a fusion protein of this enzyme with MsrB provides protection against oxidative stress in Neisseria gonorrhoeae; methionine sulfoxide reductase A 2758874 3237012 SACOL2683 Staphylococcus aureus subsp. aureus COL methionine sulfoxide reductase A YP_187470.1 2758398 R 93062 CDS YP_187471.1 57652401 3237013 complement(2758877..2759377) 1 NC_002951.2 identified by match to protein family HMM PF00583; acetyltransferase 2759377 3237013 SACOL2684 Staphylococcus aureus subsp. aureus COL acetyltransferase YP_187471.1 2758877 R 93062 CDS YP_187472.1 57652402 3237014 complement(2759612..2760379) 1 NC_002951.2 identified by match to protein family HMM PF02811; capsular polysaccharide biosynthesis protein Cap1C 2760379 cap1C 3237014 cap1C Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis protein Cap1C YP_187472.1 2759612 R 93062 CDS YP_187473.1 57652403 3237015 complement(2760376..2761068) 1 NC_002951.2 identified by similarity to EGAD:13148; match to protein family HMM TIGR01007; capsular polysaccharide biosynthesis protein Cap1B 2761068 cap1B 3237015 cap1B Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis protein Cap1B YP_187473.1 2760376 R 93062 CDS YP_187474.1 57652404 3237016 complement(2761085..2761747) 1 NC_002951.2 identified by match to protein family HMM PF02706; capsular polysaccharide biosynthesis protein Cap1A 2761747 cap1A 3237016 cap1A Staphylococcus aureus subsp. aureus COL capsular polysaccharide biosynthesis protein Cap1A YP_187474.1 2761085 R 93062 CDS YP_187475.1 57652405 3237017 complement(2762596..2763156) 1 NC_002951.2 identified by similarity to GP:5813900; similarity to OMNI:SA2688; match to protein family HMM PF00440; intercellular adhesion regulator 2763156 icaR 3237017 icaR Staphylococcus aureus subsp. aureus COL intercellular adhesion regulator YP_187475.1 2762596 R 93062 CDS YP_187476.1 57652406 3237003 2763320..2764558 1 NC_002951.2 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 2764558 icaA 3237003 icaA Staphylococcus aureus subsp. aureus COL N-glycosyltransferase YP_187476.1 2763320 D 93062 CDS YP_187477.1 57651060 3238686 2764522..2764827 1 NC_002951.2 intercellular adhesion protein D 2764827 icaD 3238686 icaD Staphylococcus aureus subsp. aureus COL intercellular adhesion protein D YP_187477.1 2764522 D 93062 CDS YP_187478.1 57651061 3238687 2764824..2765702 1 NC_002951.2 identified by match to protein family HMM PF01522; intercellular adhesion protein B 2765702 icaB 3238687 icaB Staphylococcus aureus subsp. aureus COL intercellular adhesion protein B YP_187478.1 2764824 D 93062 CDS YP_187479.1 57651381 3237117 complement(2767032..2767097) 1 NC_002951.2 hypothetical protein 2767097 3237117 SACOL2693 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187479.1 2767032 R 93062 CDS YP_187480.1 57651062 3238361 complement(2767125..2769167) 1 NC_002951.2 identified by similarity to SP:Q02510; similarity to EGAD:17843; match to protein family HMM PF04650; match to protein family HMM TIGR01168; lipase 2769167 geh 3238361 geh Staphylococcus aureus subsp. aureus COL lipase YP_187480.1 2767125 R 93062 CDS YP_187481.1 57651063 3238362 complement(2769888..2770100) 1 NC_002951.2 hypothetical protein 2770100 3238362 SACOL2695 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187481.1 2769888 R 93062 CDS YP_187482.1 57651064 3238363 complement(2770260..2770892) 1 NC_002951.2 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP 2770892 hisI 3238363 hisI Staphylococcus aureus subsp. aureus COL bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP YP_187482.1 2770260 R 93062 CDS YP_187483.1 57651065 3238650 complement(2770889..2771647) 1 NC_002951.2 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2771647 hisF 3238650 hisF Staphylococcus aureus subsp. aureus COL imidazole glycerol phosphate synthase subunit HisF YP_187483.1 2770889 R 93062 CDS YP_187484.1 57651066 3238651 complement(2771644..2772348) 1 NC_002951.2 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-hosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2772348 hisA 3238651 hisA Staphylococcus aureus subsp. aureus COL 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_187484.1 2771644 R 93062 CDS YP_187485.1 57651067 3238652 complement(2772341..2772919) 1 NC_002951.2 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2772919 hisH 3238652 hisH Staphylococcus aureus subsp. aureus COL imidazole glycerol phosphate synthase subunit HisH YP_187485.1 2772341 R 93062 CDS YP_187486.1 57651068 3238668 complement(2772916..2773494) 1 NC_002951.2 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 2773494 hisB 3238668 hisB Staphylococcus aureus subsp. aureus COL imidazoleglycerol-phosphate dehydratase YP_187486.1 2772916 R 93062 CDS YP_187487.1 57651069 3238669 complement(2773463..2774476) 1 NC_002951.2 identified by match to protein family HMM PF00155; histidinol-phosphate aminotransferase 2774476 3238669 SACOL2701 Staphylococcus aureus subsp. aureus COL histidinol-phosphate aminotransferase YP_187487.1 2773463 R 93062 CDS YP_187488.1 57651070 3238670 complement(2774492..2775748) 1 NC_002951.2 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2775748 hisD 3238670 hisD Staphylococcus aureus subsp. aureus COL histidinol dehydrogenase YP_187488.1 2774492 R 93062 CDS YP_187489.1 57651071 3238449 complement(2775735..2776349) 1 NC_002951.2 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase catalytic subunit 2776349 hisG 3238449 hisG Staphylococcus aureus subsp. aureus COL ATP phosphoribosyltransferase catalytic subunit YP_187489.1 2775735 R 93062 CDS YP_187490.1 57651072 3238450 complement(2776367..2777185) 1 NC_002951.2 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase regulatory subunit 2777185 hisZ 3238450 hisZ Staphylococcus aureus subsp. aureus COL ATP phosphoribosyltransferase regulatory subunit YP_187490.1 2776367 R 93062 CDS YP_187491.1 57651073 3238451 complement(2777490..2778614) 1 NC_002951.2 hypothetical protein 2778614 3238451 SACOL2705 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187491.1 2777490 R 93062 CDS YP_187492.1 57651074 3238452 complement(2778732..2779229) 1 NC_002951.2 hypothetical protein 2779229 3238452 SACOL2706 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187492.1 2778732 R 93062 CDS YP_187493.1 57651075 3238438 complement(2779276..2780109) 1 NC_002951.2 identified by match to protein family HMM PF02361; cobalt transport family protein 2780109 3238438 SACOL2707 Staphylococcus aureus subsp. aureus COL cobalt transport family protein YP_187493.1 2779276 R 93062 CDS YP_187494.1 57651076 3238439 complement(2780106..2781818) 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2781818 3238439 SACOL2708 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_187494.1 2780106 R 93062 CDS YP_187495.1 57651077 3238440 complement(2781871..2782425) 1 NC_002951.2 identified by match to protein family HMM PF07155; hypothetical protein 2782425 3238440 SACOL2709 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187495.1 2781871 R 93062 CDS YP_187496.1 57651078 3238075 complement(2782454..2783302) 1 NC_002951.2 identified by similarity to EGAD:167429; match to protein family HMM PF01887; hypothetical protein 2783302 3238075 SACOL2710 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187496.1 2782454 R 93062 CDS YP_187497.1 57651079 3238076 2783682..2784197 1 NC_002951.2 identified by match to protein family HMM PF04264; hypothetical protein 2784197 3238076 SACOL2711 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187497.1 2783682 D 93062 CDS YP_187498.1 57651080 3238077 complement(2784346..2785317) 1 NC_002951.2 identified by similarity to GP:6441050; drP35 protein 2785317 drp35 3238077 drp35 Staphylococcus aureus subsp. aureus COL drP35 protein YP_187498.1 2784346 R 93062 CDS YP_187499.1 57651081 3238078 2785561..2786517 1 NC_002951.2 identified by match to protein family HMM PF00581; hypothetical protein 2786517 3238078 SACOL2713 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187499.1 2785561 D 93062 CDS YP_187500.1 57651082 3238254 2786669..2787307 1 NC_002951.2 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 2787307 pcp 3238254 pcp Staphylococcus aureus subsp. aureus COL pyrrolidone-carboxylate peptidase YP_187500.1 2786669 D 93062 CDS YP_187501.1 57651083 3238255 complement(2787426..2788193) 1 NC_002951.2 hypothetical protein 2788193 3238255 SACOL2715 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187501.1 2787426 R 93062 CDS YP_187502.1 57651084 3238256 complement(2788183..2788521) 1 NC_002951.2 identified by match to protein family HMM PF03551; hypothetical protein 2788521 3238256 SACOL2716 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187502.1 2788183 R 93062 CDS YP_187503.1 57651085 3238654 2788688..2789152 1 NC_002951.2 hypothetical protein 2789152 3238654 SACOL2717 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187503.1 2788688 D 93062 CDS YP_187504.1 57651086 3238655 2789390..2790808 1 NC_002951.2 identified by match to protein family HMM PF00939; match to protein family HMM TIGR00785; anion transporter family protein 2790808 3238655 SACOL2718 Staphylococcus aureus subsp. aureus COL anion transporter family protein YP_187504.1 2789390 D 93062 CDS YP_187505.1 57651087 3238656 complement(2791221..2792129) 1 NC_002951.2 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688; rarD protein 2792129 rarD 3238656 rarD Staphylococcus aureus subsp. aureus COL rarD protein YP_187505.1 2791221 R 93062 CDS YP_187506.1 57651088 3238657 2792354..2792929 1 NC_002951.2 hypothetical protein 2792929 3238657 SACOL2720 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187506.1 2792354 D 93062 CDS YP_187507.1 57651089 3237622 2793058..2794110 1 NC_002951.2 identified by similarity to EGAD:33273; match to protein family HMM PF03824; match to protein family HMM TIGR00802; high-affinity nickel-transport protein 2794110 nixA 3237622 nixA Staphylococcus aureus subsp. aureus COL high-affinity nickel-transport protein YP_187507.1 2793058 D 93062 CDS YP_187508.1 57651090 3237623 2794353..2795147 1 NC_002951.2 identified by match to protein family HMM PF00797; N-acetyltransferase 2795147 3237623 SACOL2722 Staphylococcus aureus subsp. aureus COL N-acetyltransferase YP_187508.1 2794353 D 93062 CDS YP_187509.1 57651091 3237624 complement(2795281..2795793) 1 NC_002951.2 hypothetical protein 2795793 3237624 SACOL2723 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187509.1 2795281 R 93062 CDS YP_187510.1 57651092 3237625 2796076..2796834 1 NC_002951.2 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 2796834 3237625 SACOL2724 Staphylococcus aureus subsp. aureus COL ABC transporter ATP-binding protein YP_187510.1 2796076 D 93062 CDS YP_187511.1 57651093 3236848 2796824..2798704 1 NC_002951.2 identified by match to protein family HMM PF02687; ABC transporter permease 2798704 3236848 SACOL2725 Staphylococcus aureus subsp. aureus COL ABC transporter permease YP_187511.1 2796824 D 93062 CDS YP_187512.1 57651094 3236849 2798797..2798988 1 NC_002951.2 hypothetical protein 2798988 3236849 SACOL2726 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187512.1 2798797 D 93062 CDS YP_187513.1 57651095 3236850 2799000..2799536 1 NC_002951.2 identified by match to protein family HMM PF00665; integrase/recombinase core subunit 2799536 3236850 SACOL2727 Staphylococcus aureus subsp. aureus COL integrase/recombinase core subunit YP_187513.1 2799000 D 93062 CDS YP_187514.1 57651096 3236851 complement(2799596..2800093) 1 NC_002951.2 hypothetical protein 2800093 3236851 SACOL2728 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187514.1 2799596 R 93062 CDS YP_187515.1 57651097 3238396 2800172..2800522 1 NC_002951.2 integrase/recombinase core subunit 2800522 3238396 SACOL2729 Staphylococcus aureus subsp. aureus COL integrase/recombinase core subunit YP_187515.1 2800172 D 93062 CDS YP_187516.1 57651098 3238397 2800551..2800742 1 NC_002951.2 hypothetical protein 2800742 3238397 SACOL2730 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187516.1 2800551 D 93062 CDS YP_187517.1 57651099 3238398 2801135..2801335 1 NC_002951.2 identified by match to protein family HMM PF00313; CSD family cold shock protein 2801335 3238398 SACOL2731 Staphylococcus aureus subsp. aureus COL CSD family cold shock protein YP_187517.1 2801135 D 93062 CDS YP_187518.1 57651100 3238399 complement(2801462..2802031) 1 NC_002951.2 identified by match to protein family HMM PF01381; transcriptional regulator 2802031 3238399 SACOL2732 Staphylococcus aureus subsp. aureus COL transcriptional regulator YP_187518.1 2801462 R 93062 CDS YP_187519.1 57651101 3236122 complement(2802291..2802671) 1 NC_002951.2 identified by similarity to GB:AAO06054.1; hypothetical protein 2802671 3236122 SACOL2733 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187519.1 2802291 R 93062 CDS YP_187520.1 57651102 3236123 complement(2802754..2803107) 1 NC_002951.2 identified by similarity to GB:AAO06055.1; hypothetical protein 2803107 3236123 SACOL2734 Staphylococcus aureus subsp. aureus COL hypothetical protein YP_187520.1 2802754 R 93062 CDS YP_187521.1 57651103 3236124 complement(2803561..2804400) 1 NC_002951.2 identified by similarity to SP:P26497; match to protein family HMM PF02195; match to protein family HMM TIGR00180; ParB family chromosome partioning protein 2804400 3236124 SACOL2735 Staphylococcus aureus subsp. aureus COL ParB family chromosome partioning protein YP_187521.1 2803561 R 93062 CDS YP_187522.1 57651104 3236125 complement(2804443..2805162) 1 NC_002951.2 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 2805162 gidB 3236125 gidB Staphylococcus aureus subsp. aureus COL 16S rRNA methyltransferase GidB YP_187522.1 2804443 R 93062 CDS YP_187523.1 57651105 3236264 complement(2805162..2807039) 1 NC_002951.2 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 2807039 gidA 3236264 gidA Staphylococcus aureus subsp. aureus COL tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_187523.1 2805162 R 93062 CDS YP_187524.1 57651106 3236265 complement(2807106..2808485) 1 NC_002951.2 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 2808485 trmE 3236265 trmE Staphylococcus aureus subsp. aureus COL tRNA modification GTPase TrmE YP_187524.1 2807106 R 93062 CDS YP_187525.1 57651107 3236266 complement(2808624..2808971) 1 NC_002951.2 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 2808971 rnpA 3236266 rnpA Staphylococcus aureus subsp. aureus COL ribonuclease P YP_187525.1 2808624 R 93062 CDS YP_187526.1 57651108 3236024 complement(2809098..2809235) 1 NC_002951.2 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 2809235 rpmH 3236024 rpmH Staphylococcus aureus subsp. aureus COL 50S ribosomal protein L34 YP_187526.1 2809098 R 93062 CDS YP_184747.1 57659842 3237996 32..976 1 NC_006629.2 identified by similarity to EGAD:10909; match to protein family HMM PF02486; replication initiation protein 976 repC 3237996 repC Staphylococcus aureus subsp. aureus COL replication initiation protein YP_184747.1 32 D 93062 CDS YP_184748.1 57659841 3237997 1138..2517 1 NC_006629.2 identified by similarity to EGAD:6626; match to protein family HMM PF07690; tetracycline resistance protein 2517 tet 3237997 tet Staphylococcus aureus subsp. aureus COL tetracycline resistance protein YP_184748.1 1138 D 93062 CDS YP_184749.1 57659840 3237995 2703..3944 1 NC_006629.2 identified by similarity to EGAD:21785; match to protein family HMM PF01076; plasmid recombination enzyme 3944 pre 3237995 pre Staphylococcus aureus subsp. aureus COL plasmid recombination enzyme YP_184749.1 2703 D 93062 CDS