-- dump date 20140620_074328 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_042134.1 49484913 2862485 517..1878 1 NC_002953.3 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1878 dnaA 2862485 dnaA Staphylococcus aureus subsp. aureus MSSA476 chromosomal replication initiation protein YP_042134.1 517 D 282459 CDS YP_042135.1 49484914 2863534 2156..3289 1 NC_002953.3 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 3289 2863534 SAS0002 Staphylococcus aureus subsp. aureus MSSA476 DNA polymerase III subunit beta YP_042135.1 2156 D 282459 CDS YP_042136.1 49484915 2863844 3670..3915 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0003; hypothetical protein 3915 2863844 SAS0003 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042136.1 3670 D 282459 CDS YP_042137.1 49484916 2863845 3912..5024 1 NC_002953.3 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 5024 recF 2863845 recF Staphylococcus aureus subsp. aureus MSSA476 recombination protein F YP_042137.1 3912 D 282459 CDS YP_042138.1 49484917 2863525 5037..6968 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0005; DNA gyrase subunit B 6968 2863525 SAS0005 Staphylococcus aureus subsp. aureus MSSA476 DNA gyrase subunit B YP_042138.1 5037 D 282459 CDS YP_042139.1 49484918 2863526 7005..9668 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0006; DNA gyrase subunit A 9668 2863526 SAS0006 Staphylococcus aureus subsp. aureus MSSA476 DNA gyrase subunit A YP_042139.1 7005 D 282459 CDS YP_042140.1 49484919 2863330 complement(9755..10585) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0007; hypothetical protein 10585 2863330 SAS0007 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042140.1 9755 R 282459 CDS YP_042141.1 49484920 2862922 10893..12407 1 NC_002953.3 catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase 12407 hutH 2862922 hutH Staphylococcus aureus subsp. aureus MSSA476 histidine ammonia-lyase YP_042141.1 10893 D 282459 CDS YP_042142.1 49484921 2862923 12786..14072 1 NC_002953.3 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 14072 2862923 SAS0009 Staphylococcus aureus subsp. aureus MSSA476 seryl-tRNA synthetase YP_042142.1 12786 D 282459 CDS YP_042143.1 49484922 2863128 14724..15419 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0010; hypothetical protein 15419 2863128 SAS0010 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042143.1 14724 D 282459 CDS YP_042144.1 49484923 2862973 15416..15745 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0011; hypothetical protein 15745 2862973 SAS0011 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042144.1 15416 D 282459 CDS YP_042145.1 49484924 2862974 16108..17076 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0012; hydrolase 17076 2862974 SAS0012 Staphylococcus aureus subsp. aureus MSSA476 hydrolase YP_042145.1 16108 D 282459 CDS YP_042146.1 49484925 2862977 17321..18307 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0013; hypothetical protein 18307 2862977 SAS0013 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042146.1 17321 D 282459 CDS YP_042147.1 49484926 2862982 18322..20289 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0014; hypothetical protein 20289 2862982 SAS0014 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042147.1 18322 D 282459 CDS YP_042148.1 49484927 2862983 20286..20732 1 NC_002953.3 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 20732 rplI 2862983 rplI Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L9 YP_042148.1 20286 D 282459 CDS YP_042149.1 49484928 2862860 20764..22164 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0016; replicative DNA helicase 22164 2862860 SAS0016 Staphylococcus aureus subsp. aureus MSSA476 replicative DNA helicase YP_042149.1 20764 D 282459 CDS YP_042150.1 49484929 2862094 22443..23726 1 NC_002953.3 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 23726 2862094 SAS0017 Staphylococcus aureus subsp. aureus MSSA476 adenylosuccinate synthetase YP_042150.1 22443 D 282459 CDS YP_042151.1 49484930 2862095 24924..25631 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0018; response regulator protein 25631 2862095 SAS0018 Staphylococcus aureus subsp. aureus MSSA476 response regulator protein YP_042151.1 24924 D 282459 CDS YP_042152.1 49484931 2861788 25644..27470 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0019; sensor kinase 27470 2861788 SAS0019 Staphylococcus aureus subsp. aureus MSSA476 sensor kinase YP_042152.1 25644 D 282459 CDS YP_042153.1 49484932 2863016 27463..28797 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0020; hypothetical protein 28797 2863016 SAS0020 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042153.1 27463 D 282459 CDS YP_042154.1 49484933 2863017 28798..29586 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0021; hypothetical protein 29586 2863017 SAS0021 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042154.1 28798 D 282459 CDS YP_042155.1 49484934 2863002 29975..30775 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0022; metallo-beta-lactamase superfamily protein 30775 2863002 SAS0022 Staphylococcus aureus subsp. aureus MSSA476 metallo-beta-lactamase superfamily protein YP_042155.1 29975 D 282459 CDS YP_042156.1 49484935 2861765 30961..33321 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0023; 5'-nucleotidase 33321 2861765 SAS0023 Staphylococcus aureus subsp. aureus MSSA476 5'-nucleotidase YP_042156.1 30961 D 282459 CDS YP_042157.1 49484936 2861766 33689..34168 1 NC_002953.3 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 34168 2861766 SAS0024 Staphylococcus aureus subsp. aureus MSSA476 rRNA large subunit methyltransferase YP_042157.1 33689 D 282459 CDS YP_042158.1 49484937 2861763 complement(34546..37584) 1 NC_002953.3 N-terminus is similar to the N_terminal region of Escherichia coli type I restriction enzyme EcoR124II R protein HsdR or Hsr SWALL:T1R1_ECOLI (SWALL:P10486) (1033 aa) fasta scores: E(): 2.1e-05, 22.57% id in 762 aa. Full length CDS is similar to Caulobacter crescentus hypothetical protein CC0623 SWALL:Q9AAH5 (EMBL:AE005738) (964 aa) fasta scores: E(): 2.5e-103, 37.74% id in 959 aa; type I restriction enzyme protein 37584 2861763 SAS0025 Staphylococcus aureus subsp. aureus MSSA476 type I restriction enzyme protein YP_042158.1 34546 R 282459 CDS YP_042159.1 49484938 2864389 complement(37588..38898) 1 NC_002953.3 Similar to Escherichia coli type I restriction enzyme EcoBI specificity protein HsdS or Hss SWALL:T1SB_ECOLI (SWALL:P06990) (474 aa) fasta scores: E(): 3.7e-10, 21.44% id in 443 aa, and to Caulobacter crescentus type I restriction-modification system, S subunit CC0621 SWALL:Q9AAH7 (EMBL:AE005738) (450 aa) fasta scores: E(): 9.9e-18, 23.18% id in 440 aa; type I restriction enzyme specificity protein 38898 2864389 SAS0026 Staphylococcus aureus subsp. aureus MSSA476 type I restriction enzyme specificity protein YP_042159.1 37588 R 282459 CDS YP_042160.1 49484939 2864390 complement(38891..40678) 1 NC_002953.3 Similar to Escherichia coli type I restriction enzyme EcoR124II M protein HsdM or Hsm SWALL:T1M1_ECOLI (SWALL:P10484) (520 aa) fasta scores: E(): 8.6e-16, 23.81% id in 504 aa, and to Caulobacter crescentus type I restriction-modification system, M subunit, CC0620 SWALL:Q9AAH8 (EMBL:AE005738) (611 aa) fasta scores: E(): 2.1e-72, 42.97% id in 605 aa; type I restriction enzyme methylase 40678 2864390 SAS0027 Staphylococcus aureus subsp. aureus MSSA476 type I restriction enzyme methylase YP_042160.1 38891 R 282459 CDS YP_042161.1 49484940 2864039 complement(40866..41087) 1 NC_002953.3 Similar to Staphylococcus aureus hypothetical 9.2 kDa protein SWALL:Q93IA3 (EMBL:AB037671) (80 aa) fasta scores: E(): 1.1e-24, 89.04% id in 73 aa, and to Staphylococcus aureus hypothetical 8.0 kDa protein SWALL:Q93ID7 (EMBL:AB037671) (68 aa) fasta scores: E(): 0.0037, 33.33% id in 54 aa; hypothetical protein 41087 2864039 SAS0028 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042161.1 40866 R 282459 CDS YP_042162.1 49484941 2863985 complement(41101..41604) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0056; Similar to Staphylococcus aureus hypothetical protein SA0054 SWALL:Q99XD7 (EMBL:AP003358) (172 aa) fasta scores: E(): 2.6e-59, 94.61% id in 167 aa; hypothetical protein 41604 2863985 SAS0029 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042162.1 41101 R 282459 CDS YP_042163.1 49484942 2863986 complement(41620..41931) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0057; Similar to Staphylococcus hominis hypothetical protein Orf11 SWALL:Q8VUW8 (EMBL:AB063171) (103 aa) fasta scores: E(): 1.7e-36, 93.2% id in 103 aa; hypothetical protein 41931 2863986 SAS0030 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042163.1 41620 R 282459 CDS YP_042164.1 49484943 2862750 complement(42024..42365) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0058; Similar to Staphylococcus aureus hypothetical 13.8 kDa protein SWALL:Q9LBZ1 (EMBL:AB033763) (116 aa) fasta scores: E(): 3.7e-44, 96.42% id in 112 aa; hypothetical protein 42365 2862750 SAS0031 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042164.1 42024 R 282459 CDS YP_042165.1 49484944 2864289 complement(42831..44456) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0059; Similar to Staphylococcus hominis site-specific recombinase CcrB1 SWALL:BAB83487 (EMBL:AB063171) (542 aa) fasta scores: E(): 2.8e-179, 95.01% id in 542 aa, and to Staphylococcus aureus cassette chromosome recombinase B CcrB or CcrB3 SWALL:Q9R3U2 (EMBL:AB014437) (542 aa) fasta scores: E(): 4.3e-163, 85.79% id in 542 aa; site-specific recombinase 44456 ccrB 2864289 ccrB Staphylococcus aureus subsp. aureus MSSA476 site-specific recombinase YP_042165.1 42831 R 282459 CDS YP_042166.1 49484945 2864288 complement(44478..45827) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0060; Similar to Staphylococcus hominis site-specific recombinase CcrA1 SWALL:Q8VUX1 (EMBL:AB063171) (449 aa) fasta scores: E(): 1e-161, 94.87% id in 449 aa, and to Staphylococcus aureus cassette chromosome recombinase A1 CcrA1 SWALL:Q9S0L6 (EMBL:AB033763) (449 aa) fasta scores: E(): 3.6e-161, 94.65% id in 449 aa; site-specific recombinase 45827 ccrA1 2864288 ccrA1 Staphylococcus aureus subsp. aureus MSSA476 site-specific recombinase YP_042166.1 44478 R 282459 CDS YP_042167.1 49484946 2861797 complement(46015..47784) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0061; Similar to Staphylococcus hominis DNA, cassette chromosome SCC, strain:ATCC27844 hypothetical protein SWALL:Q8VUX3 (EMBL:AB063171) (589 aa) fasta scores: E(): 2.5e-202, 89.47% id in 589 aa, and to Staphylococcus aureus hypothetical protein SWALL:Q9S0L7 (EMBL:AB033763) (589 aa) fasta scores: E(): 1e-201, 88.79% id in 589 aa; hypothetical protein 47784 2861797 SAS0034 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042167.1 46015 R 282459 CDS YP_042168.1 49484947 2861798 complement(47784..48080) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0062; Similar to Staphylococcus aureus hypothetical 11.1 kDa protein SWALL:Q9LBZ5 (EMBL:AB033763) (98 aa) fasta scores: E(): 1e-34, 88.77% id in 98 aa, and to Staphylococcus hominis DNA, cassette chromosome scc, strain:ATCC27844 hypothetical protein SWALL:Q8VUX4 (EMBL:AB063171) (98 aa) fasta scores: E(): 7.5e-33, 84.69% id in 98 aa; hypothetical protein 48080 2861798 SAS0035 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042168.1 47784 R 282459 CDS YP_042169.1 49484948 2863284 complement(48253..49740) 1 NC_002953.3 Poor database matches. N-terminus is similar to the N-terminal region of Ureaplasma parvum hypothetical membrane lipoprotein UU125 SWALL:Q9PR19 (EMBL:AE002113) (394 aa) fasta scores: E(): 0.0071, 23.33% id in 330 aa; hypothetical protein 49740 2863284 SAS0036 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042169.1 48253 R 282459 CDS YP_042170.1 49484949 2863371 49912..50616 1 NC_002953.3 hypothetical protein 50616 2863371 SAS0037 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042170.1 49912 D 282459 CDS YP_042171.1 49484950 2863372 50640..51482 1 NC_002953.3 Poor database matches C-terminal region is similar to Brucella melitensis hypothetical protein BMEI1674 SWALL:Q8YF53 (EMBL:AE009602) (250 aa) fasta scores: E(): 1e-10, 32.61% id in 233 aa. CDS contains a coiled-coil region, residues 62 to 85; hypothetical protein 51482 2863372 SAS0038 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042171.1 50640 D 282459 CDS YP_042172.1 49484951 2863375 51926..52234 1 NC_002953.3 No significant database matches. Doubtful CDS; hypothetical protein 52234 2863375 SAS0040 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042172.1 51926 D 282459 CDS YP_042173.1 49484952 2863381 52820..53458 1 NC_002953.3 Similar to Staphylococcus aureus fusidic acid resistance protein Far1 SWALL:Q8GNY5 (EMBL:AF468686) (213 aa) fasta scores: E(): 7.8e-28, 43.68% id in 206 aa; fusidic acid resistance protein 53458 2863381 SAS0043 Staphylococcus aureus subsp. aureus MSSA476 fusidic acid resistance protein YP_042173.1 52820 D 282459 CDS YP_042174.1 49484953 2863382 54144..54773 1 NC_002953.3 Similar to Xylella fastidiosa hypothetical protein XF0543 SWALL:Q9PFW4 (EMBL:AE003901) (222 aa) fasta scores: E(): 0.0072, 26.94% id in 219 aa. N-terminal region is similar to Streptococcus pneumoniae hypothetical protein SP1047 SWALL:Q97QZ5 (EMBL:AE007407) (105 aa) fasta scores: E(): 9.9e-07, 38.09% id in 105 aa; hypothetical protein 54773 2863382 SAS0044 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042174.1 54144 D 282459 CDS YP_042175.1 49484954 2863358 complement(55452..55880) 1 NC_002953.3 Similar to Escherichia coli phnB protein PhnB SWALL:PHNB_ECOLI (SWALL:P16681) (147 aa) fasta scores: E(): 0.046, 22.55% id in 133 aa, and to Clostridium acetobutylicum uncharacterized conserved protein, phnb family CAC3689 SWALL:Q97D00 (EMBL:AE007864) (137 aa) fasta scores: E(): 3.3e-06, 31.49% id in 127 aa; hypothetical protein 55880 2863358 SAS0046 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042175.1 55452 R 282459 CDS YP_042176.1 49484955 2862655 55960..56889 1 NC_002953.3 Similar to Bacillus halodurans hypothetical protein BH1889 SWALL:Q9KBN6 (EMBL:AP001513) (325 aa) fasta scores: E(): 5.2e-16, 25.71% id in 315 aa, and to Listeria monocytogenes hypothetical protein LMO0364 SWALL:Q8YA03 (EMBL:AL591975) (314 aa) fasta scores: E(): 1.7e-15, 24.44% id in 315 aa; hypothetical protein 56889 2862655 SAS0047 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042176.1 55960 D 282459 CDS YP_042177.1 49484956 2862656 57181..58476 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0025; Similar to Staphylococcus aureus region mecA element hypothetical protein Orf1260 SWALL:Q9KJC5 (EMBL:AF181950) (419 aa) fasta scores: E(): 2.2e-138, 93.51% id in 416 aa. Weakly similar to Listeria monocytogenes hypothetical protein LMO0304 SWALL:Q8YA57 (EMBL:AL591974) (421 aa) fasta scores: E(): 2.1e-18, 27.65% id in 434 aa; hypothetical protein 58476 2862656 SAS0048 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042177.1 57181 D 282459 CDS YP_042178.1 49484957 2862465 60231..60956 1 NC_002953.3 Identical to Staphylococcus aureus enterotoxin H Seh SWALL:Q53585 (EMBL:U11702) (241 aa) fasta scores: E(): 1.2e-84, 100% id in 241 aa. Similar to Staphylococcus aureus enterotoxin type E precursor EntE SWALL:ETXE_STAAU (SWALL:P12993) (257 aa) fasta scores: E(): 2.1e-21, 37.05% id in 251 aa; enterotoxin H 60956 seh 2862465 seh Staphylococcus aureus subsp. aureus MSSA476 enterotoxin H YP_042178.1 60231 D 282459 CDS YP_042179.1 49484958 2863440 61852..62325 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0098; acetyltransferase (GNAT) family protein 62325 2863440 SAS0053 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase (GNAT) family protein YP_042179.1 61852 D 282459 CDS YP_042180.1 49484959 2862672 complement(62876..63631) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0048; hypothetical protein 63631 2862672 SAS0054 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042180.1 62876 R 282459 CDS YP_042181.1 49484960 2862673 complement(63631..63897) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0047; hypothetical protein 63897 2862673 SAS0055 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042181.1 63631 R 282459 CDS YP_042182.1 49484961 2863478 64028..65095 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0046; hypothetical protein 65095 2863478 SAS0056 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042182.1 64028 D 282459 CDS YP_042183.1 49484962 2863462 65126..66460 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0044; metallo-beta-lactamase superfamily protein 66460 2863462 SAS0057 Staphylococcus aureus subsp. aureus MSSA476 metallo-beta-lactamase superfamily protein YP_042183.1 65126 D 282459 CDS YP_042184.1 49484963 2863463 66479..67672 1 NC_002953.3 Similar to the C-terminal region of Schizosaccharomyces pombe sulfide:quinone oxidoreductase, mitochondrial precursor HMT2 or CAD1 or SPBC2G5.06c SWALL:HMT2_SCHPO (SWALL:O94284) (459 aa) fasta scores: E(): 9.1e-52, 39.36% id in 409 aa, and to the full length Bacillus cereus sulfide-quinone reductase bc3512 SWALL:Q81AP8 (EMBL:AE017009) (399 aa) fasta scores: E(): 3.3e-87, 54.7% id in 393 aa; oxidoreductase 67672 2863463 SAS0058 Staphylococcus aureus subsp. aureus MSSA476 oxidoreductase YP_042184.1 66479 D 282459 CDS YP_042185.1 49484964 2863645 complement(68339..69325) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0099; hypothetical protein 69325 2863645 SAS0059 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042185.1 68339 R 282459 CDS YP_042186.1 49484965 2863051 69634..69837 1 NC_002953.3 Similar to the C-terminal region of Bacillus anthracis hypothetical protein ba2438 SWALL:Q81QI7 (EMBL:AE017031) (81 aa) fasta scores: E(): 2.2, 33.87% id in 62 aa. Weakly similar to Escherichia coli microcin M imunity protein McmI SWALL:Q83TS3 (EMBL:AJ515251) (73 aa) fasta scores: E(): 7.7, 27.77% id in 54 aa; hypothetical protein 69837 2863051 SAS0060 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042186.1 69634 D 282459 CDS YP_042187.1 49484966 2863052 69886..70182 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0101; hypothetical protein 70182 2863052 SAS0061 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042187.1 69886 D 282459 CDS YP_042188.1 49484967 2862602 complement(70254..71474) 1 NC_002953.3 Similar to Lactobacillus plantarum transport protein lp_0492 SWALL:Q88Z68 (EMBL:AL935253) (403 aa) fasta scores: E(): 1.4e-51, 38.02% id in 405 aa, and to Bacillus anthracis permease, ba2277 SWALL:Q81QY7 (EMBL:AE017031) (409 aa) fasta scores: E(): 1.2e-17, 20.84% id in 403 aa; hypothetical protein 71474 2862602 SAS0062 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042188.1 70254 R 282459 CDS YP_042189.1 49484968 2863027 complement(71467..72024) 1 NC_002953.3 Similar to Bacillus subtilis hypothetical protein YwqN SWALL:P96726 (EMBL:Z92952) (181 aa) fasta scores: E(): 1.8e-24, 39.22% id in 181 aa, and to Bacillus cereus trp repressor binding protein bc5177 SWALL:Q815H5 (EMBL:AE017014) (181 aa) fasta scores: E(): 1.4e-23, 40.11% id in 177 aa; hypothetical protein 72024 2863027 SAS0063 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042189.1 71467 R 282459 CDS YP_042190.1 49484969 2863028 72131..72991 1 NC_002953.3 Similar to Bacillus anthracis transcriptional regulator, LysR family ba3543 SWALL:Q81YK0 (EMBL:AE017035) (297 aa) fasta scores: E(): 8.1e-19, 29.31% id in 290 aa. C-terminus is similar to the C-terminal region of Bacillus subtilis transcriptional regulatory protein GltR or bsu26670 SWALL:GLTR_BACSU (SWALL:P94501) (296 aa) fasta scores: E(): 3.2e-13, 27.98% id in 243 aa; LysR family regulatory protein 72991 2863028 SAS0064 Staphylococcus aureus subsp. aureus MSSA476 LysR family regulatory protein YP_042190.1 72131 D 282459 CDS YP_042191.1 49484970 2863424 complement(73346..73879) 1 NC_002953.3 Similar to Bacillus anthracis hypothetical protein BA1938 SWALL:Q81RU9 (EMBL:AE017030) (182 aa) fasta scores: E(): 1.8e-27, 45.05% id in 182 aa; hypothetical protein 73879 2863424 SAS0065 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042191.1 73346 R 282459 CDS YP_042192.1 49484971 2864070 73979..74713 1 NC_002953.3 Similar to Bacillus anthracis transcriptional regulator, LysR family ba1937 SWALL:Q81RV0 (EMBL:AE017030) (262 aa) fasta scores: E(): 2.5e-11, 28.9% id in 256 aa. C-terminus is similar to the C-terminal region of Bacillus subtilis transcriptional regulatory protein GltR or bsu26670 SWALL:GLTR_BACSU (SWALL:P94501) (296 aa) fasta scores: E(): 5.7e-06, 26.05% id in 238 aa; LysR family regulatory protein 74713 2864070 SAS0066 Staphylococcus aureus subsp. aureus MSSA476 LysR family regulatory protein YP_042192.1 73979 D 282459 CDS YP_042193.1 49484972 2864071 75138..75749 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0102; hypothetical protein 75749 2864071 SAS0067 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042193.1 75138 D 282459 CDS YP_042194.1 49484973 2863061 76016..79168 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0103; hypothetical protein 79168 2863061 SAS0068 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042194.1 76016 D 282459 CDS YP_042195.1 49484974 2863617 79225..79707 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0104; hypothetical protein 79707 2863617 SAS0069 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042195.1 79225 D 282459 CDS YP_042196.1 49484975 2863618 81118..81888 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0106; lipoprotein 81888 2863618 SAS0072 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_042196.1 81118 D 282459 CDS YP_042197.1 49484976 2863677 81940..82710 1 NC_002953.3 lipoprotein 82710 2863677 SAS0073 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_042197.1 81940 D 282459 CDS YP_042198.1 49484977 2864298 82989..83753 1 NC_002953.3 lipoprotein 83753 2864298 SAS0074 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_042198.1 82989 D 282459 CDS YP_042199.1 49484978 2864299 83756..85132 1 NC_002953.3 Weakly similar to Listeria monocytogenes hypothetical protein lmo2804 SWALL:Q8Y3N1 (EMBL:AL591984) (427 aa) fasta scores: E(): 3.9e-10, 25.56% id in 442 aa, and Listeria innocua hypothetical protein lin2936 SWALL:Q926V4 (EMBL:AL596174) (427 aa) fasta scores: E(): 1.4e-08, 24.44% id in 454 aa; hypothetical protein 85132 2864299 SAS0075 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042199.1 83756 D 282459 CDS YP_042200.1 49484979 2862233 85132..85458 1 NC_002953.3 Poor database matches. Weakly similar to Streptococcus agalactiae hypothetical protein gbs1827 SWALL:Q8E3D2 (EMBL:AL766853) (130 aa) fasta scores: E(): 5.7, 25.77% id in 97 aa; hypothetical protein 85458 2862233 SAS0076 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042200.1 85132 D 282459 CDS YP_042201.1 49484980 2864086 85462..85773 1 NC_002953.3 hypothetical protein 85773 2864086 SAS0077 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042201.1 85462 D 282459 CDS YP_042202.1 49484981 2864087 86025..88262 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0107; regulatory protein 88262 2864087 SAS0078 Staphylococcus aureus subsp. aureus MSSA476 regulatory protein YP_042202.1 86025 D 282459 CDS YP_042203.1 49484982 2864226 88413..89591 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0108; peptidase 89591 2864226 SAS0079 Staphylococcus aureus subsp. aureus MSSA476 peptidase YP_042203.1 88413 D 282459 CDS YP_042204.1 49484983 2864296 89593..90981 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0109; transporter protein 90981 2864296 SAS0080 Staphylococcus aureus subsp. aureus MSSA476 transporter protein YP_042204.1 89593 D 282459 CDS YP_042205.1 49484984 2864297 complement(91468..93135) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0110; Na+/Pi-cotransporter protein 93135 2864297 SAS0081 Staphylococcus aureus subsp. aureus MSSA476 Na+/Pi-cotransporter protein YP_042205.1 91468 R 282459 CDS YP_042206.1 49484985 2862282 complement(93453..95228) 1 NC_002953.3 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever; myosin-cross-reactive antigen 95228 2862282 SAS0082 Staphylococcus aureus subsp. aureus MSSA476 myosin-cross-reactive antigen YP_042206.1 93453 R 282459 CDS YP_042207.1 49484986 2864112 95579..96052 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0112; hypothetical protein 96052 2864112 SAS0083 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042207.1 95579 D 282459 CDS YP_042208.1 49484987 2864113 96314..97906 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0113; L-lactate permease 1 97906 2864113 SAS0084 Staphylococcus aureus subsp. aureus MSSA476 L-lactate permease 1 YP_042208.1 96314 D 282459 CDS YP_042209.1 49484988 2864145 complement(98235..99713) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0114; immunoglobulin G binding protein A precursor 99713 2864145 SAS0085 Staphylococcus aureus subsp. aureus MSSA476 immunoglobulin G binding protein A precursor YP_042209.1 98235 R 282459 CDS YP_042210.1 49484989 2862258 complement(100134..100886) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0115; regulatory protein 100886 2862258 SAS0086 Staphylococcus aureus subsp. aureus MSSA476 regulatory protein YP_042210.1 100134 R 282459 CDS YP_042211.1 49484990 2862259 complement(101255..102253) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0116; siderophore transport system permease 102253 2862259 SAS0087 Staphylococcus aureus subsp. aureus MSSA476 siderophore transport system permease YP_042211.1 101255 R 282459 CDS YP_042212.1 49484991 2864148 complement(102250..103245) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0117; siderophore transport system permease 103245 2864148 SAS0088 Staphylococcus aureus subsp. aureus MSSA476 siderophore transport system permease YP_042212.1 102250 R 282459 CDS YP_042213.1 49484992 2862594 complement(103261..104253) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0118; lipoprotein 104253 2862594 SAS0089 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_042213.1 103261 R 282459 CDS YP_042214.1 49484993 2862595 104484..105464 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0119; pyridoxal-phosphate dependent protein 105464 2862595 SAS0090 Staphylococcus aureus subsp. aureus MSSA476 pyridoxal-phosphate dependent protein YP_042214.1 104484 D 282459 CDS YP_042215.1 49484994 2861951 105461..106471 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0120; ornithine cyclodeaminase 106471 2861951 SAS0091 Staphylococcus aureus subsp. aureus MSSA476 ornithine cyclodeaminase YP_042215.1 105461 D 282459 CDS YP_042216.1 49484995 2861960 106492..108246 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0121; siderophore biosynthesis protein 108246 2861960 SAS0092 Staphylococcus aureus subsp. aureus MSSA476 siderophore biosynthesis protein YP_042216.1 106492 D 282459 CDS YP_042217.1 49484996 2861961 108239..109495 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0122; transport protein 109495 2861961 SAS0093 Staphylococcus aureus subsp. aureus MSSA476 transport protein YP_042217.1 108239 D 282459 CDS YP_042218.1 49484997 2862309 109485..111221 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0123; siderophore biosynthesis protein 111221 2862309 SAS0094 Staphylococcus aureus subsp. aureus MSSA476 siderophore biosynthesis protein YP_042218.1 109485 D 282459 CDS YP_042219.1 49484998 2862311 111202..112980 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0124; siderophore biosynthesis protein 112980 2862311 SAS0095 Staphylococcus aureus subsp. aureus MSSA476 siderophore biosynthesis protein YP_042219.1 111202 D 282459 CDS YP_042220.1 49484999 2862312 112955..113731 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0125; aldolase 113731 2862312 SAS0096 Staphylococcus aureus subsp. aureus MSSA476 aldolase YP_042220.1 112955 D 282459 CDS YP_042221.1 49485000 2861957 113731..114933 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0126; pyridoxal-dependent decarboxylase 114933 2861957 SAS0097 Staphylococcus aureus subsp. aureus MSSA476 pyridoxal-dependent decarboxylase YP_042221.1 113731 D 282459 CDS YP_042222.1 49485001 2862031 114937..115701 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0127; hypothetical protein 115701 2862031 SAS0098 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042222.1 114937 D 282459 CDS YP_042223.1 49485002 2862032 115897..116304 1 NC_002953.3 Poor database matches. Weakly similar to Clostridium acetobutylicum uncharacterized membrane protein cac0546 SWALL:Q97LL2 (EMBL:AE007570) (116 aa) fasta scores: E(): 1.4, 25% id in 100 aa; hypothetical protein 116304 2862032 SAS0099 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042223.1 115897 D 282459 CDS YP_042224.1 49485003 2862533 116354..116980 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0128; hypothetical protein 116980 2862533 SAS0100 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042224.1 116354 D 282459 CDS YP_042225.1 49485004 2862349 117192..117968 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0129; acetoin reductase 117968 2862349 SAS0101 Staphylococcus aureus subsp. aureus MSSA476 acetoin reductase YP_042225.1 117192 D 282459 CDS YP_042226.1 49485005 2862350 complement(118017..118166) 1 NC_002953.3 Doubtful CDS. No significant database hits; hypothetical protein 118166 2862350 SAS0101a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042226.1 118017 R 282459 CDS YP_042227.1 49485006 2861832 118313..119284 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0130; NAD dependent epimerase/dehydratase family protein 119284 2861832 SAS0102 Staphylococcus aureus subsp. aureus MSSA476 NAD dependent epimerase/dehydratase family protein YP_042227.1 118313 D 282459 CDS YP_042228.1 49485007 2862361 119247..119939 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0131; sugar transferase 119939 2862361 SAS0103 Staphylococcus aureus subsp. aureus MSSA476 sugar transferase YP_042228.1 119247 D 282459 CDS YP_042229.1 49485008 2862362 120149..121315 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0132; galactosyl transferase 121315 2862362 SAS0104 Staphylococcus aureus subsp. aureus MSSA476 galactosyl transferase YP_042229.1 120149 D 282459 CDS YP_042230.1 49485009 2863175 121296..122534 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0133; hypothetical protein 122534 2863175 SAS0105 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042230.1 121296 D 282459 CDS YP_042231.1 49485010 2862296 122524..123954 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0134; polysaccharide biosynthesis protein 123954 2862296 SAS0106 Staphylococcus aureus subsp. aureus MSSA476 polysaccharide biosynthesis protein YP_042231.1 122524 D 282459 CDS YP_042232.1 49485011 2862710 124222..124821 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0135; superoxide dismutase 124821 2862710 SAS0107 Staphylococcus aureus subsp. aureus MSSA476 superoxide dismutase YP_042232.1 124222 D 282459 CDS YP_042233.1 49485012 2862711 125189..125914 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0136; surface anchored protein 125914 2862711 SAS0108 Staphylococcus aureus subsp. aureus MSSA476 surface anchored protein YP_042233.1 125189 D 282459 CDS YP_042234.1 49485013 2863397 complement(126105..126845) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0137; GntR family transcriptional regulator 126845 2863397 SAS0109 Staphylococcus aureus subsp. aureus MSSA476 GntR family transcriptional regulator YP_042234.1 126105 R 282459 CDS YP_042235.1 49485014 2862325 127096..127803 1 NC_002953.3 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 127803 2862325 SAS0110 Staphylococcus aureus subsp. aureus MSSA476 purine nucleoside phosphorylase YP_042235.1 127096 D 282459 CDS YP_042236.1 49485015 2862326 127810..129162 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0139; transport system protein 129162 2862326 SAS0111 Staphylococcus aureus subsp. aureus MSSA476 transport system protein YP_042236.1 127810 D 282459 CDS YP_042237.1 49485016 2862098 129243..129905 1 NC_002953.3 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 129905 2862098 SAS0112 Staphylococcus aureus subsp. aureus MSSA476 deoxyribose-phosphate aldolase YP_042237.1 129243 D 282459 CDS YP_042238.1 49485017 2862099 129933..131111 1 NC_002953.3 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 131111 2862099 SAS0113 Staphylococcus aureus subsp. aureus MSSA476 phosphopentomutase YP_042238.1 129933 D 282459 CDS YP_042239.1 49485018 2862398 complement(131242..132057) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0142; binding-protein-dependent transport systems membrane component 132057 2862398 SAS0114 Staphylococcus aureus subsp. aureus MSSA476 binding-protein-dependent transport systems membrane component YP_042239.1 131242 R 282459 CDS YP_042240.1 49485019 2864265 complement(132054..132854) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0143; binding-protein-dependent transport system membrane component 132854 2864265 SAS0115 Staphylococcus aureus subsp. aureus MSSA476 binding-protein-dependent transport system membrane component YP_042240.1 132054 R 282459 CDS YP_042241.1 49485020 2864266 complement(132856..133629) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0144; ABC transporter ATP binding protein 133629 2864266 SAS0116 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP binding protein YP_042241.1 132856 R 282459 CDS YP_042242.1 49485021 2864262 complement(133843..134799) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0145; lipoprotein 134799 2864262 SAS0117 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_042242.1 133843 R 282459 CDS YP_042243.1 49485022 2862831 135028..136572 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0146; hypothetical protein 136572 2862831 SAS0118 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042243.1 135028 D 282459 CDS YP_042244.1 49485023 2862832 136623..138158 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0147; nucleotidase 138158 2862832 SAS0119 Staphylococcus aureus subsp. aureus MSSA476 nucleotidase YP_042244.1 136623 D 282459 CDS YP_042245.1 49485024 2863880 141371..143980 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0150; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 143980 2863880 SAS0123 Staphylococcus aureus subsp. aureus MSSA476 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_042245.1 141371 D 282459 CDS YP_042246.1 49485025 2863881 144318..144986 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0151; capsular polysaccharide synthesis enzyme 144986 2863881 SAS0124 Staphylococcus aureus subsp. aureus MSSA476 capsular polysaccharide synthesis enzyme YP_042246.1 144318 D 282459 CDS YP_042247.1 49485026 2864231 145002..145688 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0152; capsular polysaccharide synthesis enzyme 145688 2864231 SAS0125 Staphylococcus aureus subsp. aureus MSSA476 capsular polysaccharide synthesis enzyme YP_042247.1 145002 D 282459 CDS YP_042248.1 49485027 2861855 145691..146455 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0153; capsular polysaccharide synthesis enzyme 146455 2861855 SAS0126 Staphylococcus aureus subsp. aureus MSSA476 capsular polysaccharide synthesis enzyme YP_042248.1 145691 D 282459 CDS YP_042249.1 49485028 2863107 146475..148298 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0154; capsular polysaccharide synthesis enzyme 148298 2863107 SAS0127 Staphylococcus aureus subsp. aureus MSSA476 capsular polysaccharide synthesis enzyme YP_042249.1 146475 D 282459 CDS YP_042250.1 49485029 2862056 148288..149316 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0155; capsular polysaccharide synthesis enzyme 149316 2862056 SAS0128 Staphylococcus aureus subsp. aureus MSSA476 capsular polysaccharide synthesis enzyme YP_042250.1 148288 D 282459 CDS YP_042251.1 49485030 2862136 149329..150438 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0156; capsular polysaccharide synthesis enzyme 150438 2862136 SAS0129 Staphylococcus aureus subsp. aureus MSSA476 capsular polysaccharide synthesis enzyme YP_042251.1 149329 D 282459 CDS YP_042252.1 49485031 2862137 150442..151566 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0157; capsular polysaccharide synthesis enzyme 151566 2862137 SAS0130 Staphylococcus aureus subsp. aureus MSSA476 capsular polysaccharide synthesis enzyme YP_042252.1 150442 D 282459 CDS YP_042253.1 49485032 2862159 151569..152648 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0158; capsular polysaccharide synthesis enzyme 152648 2862159 SAS0131 Staphylococcus aureus subsp. aureus MSSA476 capsular polysaccharide synthesis enzyme YP_042253.1 151569 D 282459 CDS YP_042254.1 49485033 2863122 152641..154035 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0159; capsular polysaccharide synthesis enzyme 154035 2863122 SAS0132 Staphylococcus aureus subsp. aureus MSSA476 capsular polysaccharide synthesis enzyme YP_042254.1 152641 D 282459 CDS YP_042255.1 49485034 2863123 154032..154589 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0160; capsular polysaccharide synthesis enzyme 154589 2863123 SAS0133 Staphylococcus aureus subsp. aureus MSSA476 capsular polysaccharide synthesis enzyme YP_042255.1 154032 D 282459 CDS YP_042256.1 49485035 2863827 154598..155836 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0161; capsular polysaccharide synthesis enzyme 155836 2863827 SAS0134 Staphylococcus aureus subsp. aureus MSSA476 capsular polysaccharide synthesis enzyme YP_042256.1 154598 D 282459 CDS YP_042257.1 49485036 2863828 155870..157075 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0162; capsular polysaccharide synthesis enzyme 157075 2863828 SAS0135 Staphylococcus aureus subsp. aureus MSSA476 capsular polysaccharide synthesis enzyme YP_042257.1 155870 D 282459 CDS YP_042258.1 49485037 2862447 157086..157643 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0163; capsular polysaccharide synthesis enzyme 157643 2862447 SAS0136 Staphylococcus aureus subsp. aureus MSSA476 capsular polysaccharide synthesis enzyme YP_042258.1 157086 D 282459 CDS YP_042259.1 49485038 2862439 157643..158530 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0164; capsular polysaccharide synthesis enzyme 158530 2862439 SAS0137 Staphylococcus aureus subsp. aureus MSSA476 capsular polysaccharide synthesis enzyme YP_042259.1 157643 D 282459 CDS YP_042260.1 49485039 2862440 158584..159846 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0165; capsular polysaccharide synthesis enzyme 159846 2862440 SAS0138 Staphylococcus aureus subsp. aureus MSSA476 capsular polysaccharide synthesis enzyme YP_042260.1 158584 D 282459 CDS YP_042261.1 49485040 2863108 159893..161068 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0166; capsular polysaccharide synthesis enzyme 161068 2863108 SAS0139 Staphylococcus aureus subsp. aureus MSSA476 capsular polysaccharide synthesis enzyme YP_042261.1 159893 D 282459 CDS YP_042262.1 49485041 2863238 complement(161133..161459) 1 NC_002953.3 iron regulated; catalyzes the release of heme from hemoglobin allowing bacterial pathogens to use the host heme as an iron source; heme-degrading monooxygenase IsdI 161459 2863238 SAS0140 Staphylococcus aureus subsp. aureus MSSA476 heme-degrading monooxygenase IsdI YP_042262.1 161133 R 282459 CDS YP_042263.1 49485042 2863239 complement(161466..161849) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0168; hypothetical protein 161849 2863239 SAS0141 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042263.1 161466 R 282459 CDS YP_042264.1 49485043 2862480 162276..163763 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0169; aldehyde dehydrogenase 163763 2862480 SAS0142 Staphylococcus aureus subsp. aureus MSSA476 aldehyde dehydrogenase YP_042264.1 162276 D 282459 CDS YP_042265.1 49485044 2863161 164409..165368 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0170; cation efflux system protein 165368 2863161 SAS0143 Staphylococcus aureus subsp. aureus MSSA476 cation efflux system protein YP_042265.1 164409 D 282459 CDS YP_042266.1 49485045 2863162 165436..165702 1 NC_002953.3 Doubtful CDS. No significant database matches; hypothetical protein 165702 2863162 SAS0144 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042266.1 165436 D 282459 CDS YP_042267.1 49485046 2862888 complement(165662..165865) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0171; hypothetical protein 165865 2862888 SAS0145 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042267.1 165662 R 282459 CDS YP_042268.1 49485047 2862889 166043..166555 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0172; hypothetical protein 166555 2862889 SAS0146 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042268.1 166043 D 282459 CDS YP_042269.1 49485048 2863324 166897..167637 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0173; ABC transporter ATP-binding protein 167637 2863324 SAS0147 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042269.1 166897 D 282459 CDS YP_042270.1 49485049 2862856 167651..168625 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0174; lipoprotein 168625 2862856 SAS0148 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_042270.1 167651 D 282459 CDS YP_042271.1 49485050 2862857 168622..169383 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0175; transport system permease 169383 2862857 SAS0149 Staphylococcus aureus subsp. aureus MSSA476 transport system permease YP_042271.1 168622 D 282459 CDS YP_042272.1 49485051 2862893 169396..170427 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0176; hypothetical protein 170427 2862893 SAS0150 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042272.1 169396 D 282459 CDS YP_042273.1 49485052 2863234 170644..171003 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0177; hypothetical protein 171003 2863234 SAS0151 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042273.1 170644 D 282459 CDS YP_042274.1 49485053 2863235 171078..172202 1 NC_002953.3 Catalyzes the reversible two-electron oxidation of formate to carbon dioxide. It allows the assimilation of carbon dioxide and provides energy for growth through oxidative phosphorylation coupled to the reduction of oxygen, nitrate, sulphate or fumarate; formate dehydrogenase 172202 2863235 SAS0152 Staphylococcus aureus subsp. aureus MSSA476 formate dehydrogenase YP_042274.1 171078 D 282459 CDS YP_042275.1 49485054 2863577 172588..173838 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0179; transporter protein 173838 2863577 SAS0153 Staphylococcus aureus subsp. aureus MSSA476 transporter protein YP_042275.1 172588 D 282459 CDS YP_042276.1 49485055 2862914 174285..181460 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0180; non-ribosomal peptide synthetase 181460 2862914 SAS0154 Staphylococcus aureus subsp. aureus MSSA476 non-ribosomal peptide synthetase YP_042276.1 174285 D 282459 CDS YP_042277.1 49485056 2862915 181473..182117 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0181; 4'-phosphopantetheinyl transferase 182117 2862915 SAS0155 Staphylococcus aureus subsp. aureus MSSA476 4'-phosphopantetheinyl transferase YP_042277.1 181473 D 282459 CDS YP_042278.1 49485057 2863588 complement(182445..182939) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0182; hypothetical protein 182939 2863588 SAS0156 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042278.1 182445 R 282459 CDS YP_042279.1 49485058 2863589 complement(183194..183958) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0183; amino acid kinase 183958 2863589 SAS0157 Staphylococcus aureus subsp. aureus MSSA476 amino acid kinase YP_042279.1 183194 R 282459 CDS YP_042280.1 49485059 2863538 complement(183974..185215) 1 NC_002953.3 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 185215 argJ 2863538 argJ Staphylococcus aureus subsp. aureus MSSA476 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase YP_042280.1 183974 R 282459 CDS YP_042281.1 49485060 2863539 complement(185227..186261) 1 NC_002953.3 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 186261 argC 2863539 argC Staphylococcus aureus subsp. aureus MSSA476 N-acetyl-gamma-glutamyl-phosphate reductase YP_042281.1 185227 R 282459 CDS YP_042282.1 49485061 2863540 complement(186297..187481) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0186; ornithine aminotransferase 187481 2863540 SAS0160 Staphylococcus aureus subsp. aureus MSSA476 ornithine aminotransferase YP_042282.1 186297 R 282459 CDS YP_042283.1 49485062 2862093 complement(187734..189089) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0187; branched-chain amino acid transport system carrier protein 189089 2862093 SAS0161 Staphylococcus aureus subsp. aureus MSSA476 branched-chain amino acid transport system carrier protein YP_042283.1 187734 R 282459 CDS YP_042284.1 49485063 2862984 complement(189365..189922) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0188; isochorismatase 189922 2862984 SAS0162 Staphylococcus aureus subsp. aureus MSSA476 isochorismatase YP_042284.1 189365 R 282459 CDS YP_042285.1 49485064 2862985 complement(189989..191629) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0189; thiamine pyrophosphate enzyme 191629 2862985 SAS0163 Staphylococcus aureus subsp. aureus MSSA476 thiamine pyrophosphate enzyme YP_042285.1 189989 R 282459 CDS YP_042286.1 49485065 2863571 complement(191902..193947) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0190; glucose-specific PTS transporter protein, IIABC component 193947 2863571 SAS0164 Staphylococcus aureus subsp. aureus MSSA476 glucose-specific PTS transporter protein, IIABC component YP_042286.1 191902 R 282459 CDS YP_042287.1 49485066 2862122 194532..195587 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0191; hypothetical protein 195587 2862122 SAS0165 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042287.1 194532 D 282459 CDS YP_042288.1 49485067 2862123 195584..196483 1 NC_002953.3 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 196483 murQ 2862123 murQ Staphylococcus aureus subsp. aureus MSSA476 N-acetylmuramic acid 6-phosphate etherase YP_042288.1 195584 D 282459 CDS YP_042289.1 49485068 2862948 196495..197949 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0193; sucrose-specific PTS transporter protein 197949 2862948 SAS0167 Staphylococcus aureus subsp. aureus MSSA476 sucrose-specific PTS transporter protein YP_042289.1 196495 D 282459 CDS YP_042290.1 49485069 2862949 197949..198827 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0194; transcriptional regulator 198827 2862949 SAS0168 Staphylococcus aureus subsp. aureus MSSA476 transcriptional regulator YP_042290.1 197949 D 282459 CDS YP_042291.1 49485070 2864431 complement(199021..199302) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0195; hypothetical protein 199302 2864431 SAS0169 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042291.1 199021 R 282459 CDS YP_042292.1 49485071 2862691 199515..202304 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0196; type I restriction enzyme 202304 2862691 SAS0170 Staphylococcus aureus subsp. aureus MSSA476 type I restriction enzyme YP_042292.1 199515 D 282459 CDS YP_042293.1 49485072 2862692 complement(202451..203050) 1 NC_002953.3 Weakly similar to Cortinarius talus ATPase subunit 6 ATP6 SWALL:Q8M3Z0 (EMBL:AF388804) (214 aa) fasta scores: E(): 0.31, 25.61% id in 203 aa, and to Bacillus cereus ABC transporter permease bc4219 SWALL:Q818N0 (EMBL:AE017011) (210 aa) fasta scores: E(): 7.8, 20.31% id in 192 aa; hypothetical protein 203050 2862692 SAS0171 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042293.1 202451 R 282459 CDS YP_042294.1 49485073 2861819 203176..203931 1 NC_002953.3 Weakly similar to Oceanobacillus iheyensis hypothetical conserved protein ob2941 SWALL:Q8EMB6 (EMBL:AP004603) (287 aa) fasta scores: E(): 0.5, 22.37% id in 286 aa, and to the C-terminal region of Enterococcus faecalis hypothetical protein ef0417 SWALL:Q838M6 (EMBL:AE016948) (392 aa) fasta scores: E(): 0.0033, 24.56% id in 232 aa; hypothetical protein 203931 2861819 SAS0172 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042294.1 203176 D 282459 CDS YP_042295.1 49485074 2864391 203928..204608 1 NC_002953.3 Similar to Enterococcus faecalis ABC transporter, ATP-binding protein ef2986 SWALL:Q82ZR2 (EMBL:AE016956) (224 aa) fasta scores: E(): 7.8e-39, 54.66% id in 225 aa, and to Bacillus halodurans ABC transporter bh3673 SWALL:Q9K6Q5 (EMBL:AP001519) (227 aa) fasta scores: E(): 6e-38, 49.32% id in 223 aa; ABC transporter ATP-binding protein 204608 2864391 SAS0173 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042295.1 203928 D 282459 CDS YP_042296.1 49485075 2864392 204605..205783 1 NC_002953.3 Similar to Clostridium perfringens probable ABC transporter cpe1540 SWALL:Q8XK63 (EMBL:AP003190) (394 aa) fasta scores: E(): 1.1e-34, 34.42% id in 398 aa, and to the C-terminal region of Escherichia coli macrolide-specific ABC-type efflux carrier MacB or b0879 SWALL:MACB_ECOLI (SWALL:P75831) (648 aa) fasta scores: E(): 4.8e-24, 26.88% id in 398 aa; permease 205783 2864392 SAS0174 Staphylococcus aureus subsp. aureus MSSA476 permease YP_042296.1 204605 D 282459 CDS YP_042297.1 49485076 2864435 205990..206211 1 NC_002953.3 hypothetical protein 206211 2864435 SAS0175 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042297.1 205990 D 282459 CDS YP_042298.1 49485077 2864442 206249..207967 1 NC_002953.3 Weakly similar to Clostridium beijerinckii CirB protein SWALL:CAD97581 (EMBL:AJ566621) (581 aa) fasta scores: E(): 1.2e-10, 24.04% id in 599 aa, and Clostridium perfringens hypothetical protein cpe0306 SWALL:Q8XNM7 (EMBL:AP003186) (532 aa) fasta scores: E(): 0.013, 20.43% id in 558 aa; hypothetical protein 207967 2864442 SAS0176 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042298.1 206249 D 282459 CDS YP_042299.1 49485078 2864443 208026..208469 1 NC_002953.3 Similar to the C-terminal regions of Bacillus thuringiensis integral membrane protein pbt138 SWALL:Q8KIV7 (EMBL:AL731825) (177 aa) fasta scores: E(): 1.7e-06, 26.56% id in 128 aa, and to Methanococcus jannaschii hypothetical protein mj0793 SWALL:Y793_METJA (SWALL:Q58203) (178 aa) fasta scores: E(): 1.2e-05, 30.65% id in 137 aa; hypothetical protein 208469 2864443 SAS0177 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042299.1 208026 D 282459 CDS YP_042300.1 49485079 2863291 208481..209203 1 NC_002953.3 Weakly similar to Bacillus subtilis ATP-binding transport protein nata nata or bsu02750 SWALL:NATA_BACSU (SWALL:P46903) (246 aa) fasta scores: E(): 1e-12, 29.43% id in 214 aa, and to Clostridium tetani ABC transporter ATP-binding protein ctp37 SWALL:Q899X7 (EMBL:AF528097) (213 aa) fasta scores: E(): 8.8e-16, 35.92% id in 206 aa; ATP-binding transport protein 209203 2863291 SAS0178 Staphylococcus aureus subsp. aureus MSSA476 ATP-binding transport protein YP_042300.1 208481 D 282459 CDS YP_042301.1 49485080 2863292 209190..209366 1 NC_002953.3 Poor database matches. Similar to internal region of Salmonella typhimurium melibiose carrier protein stm4299 SWALL:MELB_SALTY (SWALL:P30878) (476 aa) fasta scores: E(): 8.7, 40.35% id in 57 aa; hypothetical protein 209366 2863292 SAS0179 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042301.1 209190 D 282459 CDS YP_042302.1 49485081 2863997 complement(209413..209601) 1 NC_002953.3 Doubtful CDS. No significant database matches; hypothetical protein 209601 2863997 SAS0180 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042302.1 209413 R 282459 CDS YP_042303.1 49485082 2863365 complement(210076..211668) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0198; ABC transporter ATP-binding protein 211668 2863365 SAS0181 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042303.1 210076 R 282459 CDS YP_042304.1 49485083 2863366 211796..213103 1 NC_002953.3 Possible alternative translational start sites. C-terminal region is similar to Bacillus subtilis dipeptide transport system permease DppB or BSU12930 SWALL:DPPB_BACSU (SWALL:P26903) (308 aa) fasta scores: E(): 8.3e-32, 32.24% id in 307 aa, and to Fusobacterium nucleatum subsp. vincentii ATCC 49256 dipeptide transport system permease FNV2131 SWALL:Q7P899 (EMBL:AABF01000003) (308 aa) fasta scores: E(): 2.2e-45, 42.67% id in 307 aa; Ortholog of S. aureus MRSA252 (BX571856) SAR0199; transport system permease 213103 2863366 SAS0182 Staphylococcus aureus subsp. aureus MSSA476 transport system permease YP_042304.1 211796 D 282459 CDS YP_042305.1 49485084 2863314 213109..214272 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0200; transport system permease 214272 2863314 SAS0183 Staphylococcus aureus subsp. aureus MSSA476 transport system permease YP_042305.1 213109 D 282459 CDS YP_042306.1 49485085 2863979 214289..216064 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0201; RGD-containing lipoprotein 216064 2863979 SAS0184 Staphylococcus aureus subsp. aureus MSSA476 RGD-containing lipoprotein YP_042306.1 214289 D 282459 CDS YP_042307.1 49485086 2863980 216102..218108 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0202; gamma-glutamyltranspeptidase 218108 2863980 SAS0185 Staphylococcus aureus subsp. aureus MSSA476 gamma-glutamyltranspeptidase YP_042307.1 216102 D 282459 CDS YP_042308.1 49485087 2863423 complement(218421..219194) 1 NC_002953.3 hypothetical protein 219194 2863423 SAS0186 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042308.1 218421 R 282459 CDS YP_042309.1 49485088 2863443 complement(219384..220010) 1 NC_002953.3 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase 220010 acpD 2863443 acpD Staphylococcus aureus subsp. aureus MSSA476 azoreductase YP_042309.1 219384 R 282459 CDS YP_042310.1 49485089 2863444 220219..220797 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0204; peptidase 220797 2863444 SAS0188 Staphylococcus aureus subsp. aureus MSSA476 peptidase YP_042310.1 220219 D 282459 CDS YP_042311.1 49485090 2863249 221180..222277 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0205; ABC transporter ATP-binding protein 222277 2863249 SAS0189 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042311.1 221180 D 282459 CDS YP_042312.1 49485091 2863250 222290..223561 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0206; extracellular sugar-binding lipoprotein 223561 2863250 SAS0190 Staphylococcus aureus subsp. aureus MSSA476 extracellular sugar-binding lipoprotein YP_042312.1 222290 D 282459 CDS YP_042313.1 49485092 2863663 223564..224832 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0207; sugar transport system permease 224832 2863663 SAS0191 Staphylococcus aureus subsp. aureus MSSA476 sugar transport system permease YP_042313.1 223564 D 282459 CDS YP_042314.1 49485093 2862598 224834..225673 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0208; sugar transport system permease 225673 2862598 SAS0192 Staphylococcus aureus subsp. aureus MSSA476 sugar transport system permease YP_042314.1 224834 D 282459 CDS YP_042315.1 49485094 2862599 225744..226823 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0209; oxidoreductase 226823 2862599 SAS0193 Staphylococcus aureus subsp. aureus MSSA476 oxidoreductase YP_042315.1 225744 D 282459 CDS YP_042316.1 49485095 2863031 226848..227888 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0210; oxidoreductase 227888 2863031 SAS0194 Staphylococcus aureus subsp. aureus MSSA476 oxidoreductase YP_042316.1 226848 D 282459 CDS YP_042317.1 49485096 2863064 227943..228911 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0211; hypothetical protein 228911 2863064 SAS0195 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042317.1 227943 D 282459 CDS YP_042318.1 49485097 2863065 complement(229272..229766) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0212; hypothetical protein 229766 2863065 SAS0196 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042318.1 229272 R 282459 CDS YP_042319.1 49485098 2863062 229999..231378 1 NC_002953.3 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 231378 uhpT 2863062 uhpT Staphylococcus aureus subsp. aureus MSSA476 sugar phosphate antiporter YP_042319.1 229999 D 282459 CDS YP_042320.1 49485099 2863636 complement(231737..232495) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0214; response regulator 232495 2863636 SAS0198 Staphylococcus aureus subsp. aureus MSSA476 response regulator YP_042320.1 231737 R 282459 CDS YP_042321.1 49485100 2863637 complement(232488..234044) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0215; sensor kinase 234044 2863637 SAS0199 Staphylococcus aureus subsp. aureus MSSA476 sensor kinase YP_042321.1 232488 R 282459 CDS YP_042322.1 49485101 2863043 complement(234041..235009) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0216; lipoprotein 235009 2863043 SAS0200 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_042322.1 234041 R 282459 CDS YP_042323.1 49485102 2863044 235597..237846 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0217; formate acetyltransferase 237846 2863044 SAS0201 Staphylococcus aureus subsp. aureus MSSA476 formate acetyltransferase YP_042323.1 235597 D 282459 CDS YP_042324.1 49485103 2864326 237869..238624 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0218; pyruvate formate-lyase activating enzyme 238624 2864326 SAS0202 Staphylococcus aureus subsp. aureus MSSA476 pyruvate formate-lyase activating enzyme YP_042324.1 237869 D 282459 CDS YP_042325.1 49485104 2863631 238614..238922 1 NC_002953.3 hypothetical protein 238922 2863631 SAS0203 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042325.1 238614 D 282459 CDS YP_042326.1 49485105 2863632 238960..240723 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0220; hypothetical protein 240723 2863632 SAS0204 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042326.1 238960 D 282459 CDS YP_042327.1 49485106 2864081 complement(240887..241231) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0221; hypothetical protein 241231 2864081 SAS0205 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042327.1 240887 R 282459 CDS YP_042328.1 49485107 2863086 241421..243322 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0222; staphylocoagulase precursor 243322 2863086 SAS0206 Staphylococcus aureus subsp. aureus MSSA476 staphylocoagulase precursor YP_042328.1 241421 D 282459 CDS YP_042329.1 49485108 2863087 complement(243925..245109) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0223; thiolase 245109 2863087 SAS0207 Staphylococcus aureus subsp. aureus MSSA476 thiolase YP_042329.1 243925 R 282459 CDS YP_042330.1 49485109 2864135 complement(245139..247400) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0224; fatty oxidation complex protein 247400 2864135 SAS0208 Staphylococcus aureus subsp. aureus MSSA476 fatty oxidation complex protein YP_042330.1 245139 R 282459 CDS YP_042331.1 49485110 2861875 complement(247587..248798) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0225; acyl-CoA dehydrogenase 248798 2861875 SAS0209 Staphylococcus aureus subsp. aureus MSSA476 acyl-CoA dehydrogenase YP_042331.1 247587 R 282459 CDS YP_042332.1 49485111 2861876 complement(248910..250415) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0226; acyl-CoA synthetase 250415 2861876 SAS0210 Staphylococcus aureus subsp. aureus MSSA476 acyl-CoA synthetase YP_042332.1 248910 R 282459 CDS YP_042333.1 49485112 2864292 complement(250441..252003) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0227; acetyl-CoA transferase 252003 2864292 SAS0211 Staphylococcus aureus subsp. aureus MSSA476 acetyl-CoA transferase YP_042333.1 250441 R 282459 CDS YP_042334.1 49485113 2864293 252459..253601 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0229; hypothetical protein 253601 2864293 SAS0212 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042334.1 252459 D 282459 CDS YP_042335.1 49485114 2864172 complement(253915..255390) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0230; extracellular solute-binding lipoprotein 255390 2864172 SAS0213 Staphylococcus aureus subsp. aureus MSSA476 extracellular solute-binding lipoprotein YP_042335.1 253915 R 282459 CDS YP_042336.1 49485115 2864163 complement(255588..255944) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0231; hypothetical protein 255944 2864163 SAS0214 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042336.1 255588 R 282459 CDS YP_042337.1 49485116 2864164 complement(256101..256274) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0232; hypothetical protein 256274 2864164 SAS0215 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042337.1 256101 R 282459 CDS YP_042338.1 49485117 2864349 complement(256300..257445) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0233; flavohemoprotein 257445 2864349 SAS0216 Staphylococcus aureus subsp. aureus MSSA476 flavohemoprotein YP_042338.1 256300 R 282459 CDS YP_042339.1 49485118 2864185 258018..258971 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0234; L-lactate dehydrogenase 258971 2864185 SAS0217 Staphylococcus aureus subsp. aureus MSSA476 L-lactate dehydrogenase YP_042339.1 258018 D 282459 CDS YP_042340.1 49485119 2864186 complement(259291..260820) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0235; PTS transport system, IIBC component 260820 2864186 SAS0218 Staphylococcus aureus subsp. aureus MSSA476 PTS transport system, IIBC component YP_042340.1 259291 R 282459 CDS YP_042341.1 49485120 2864144 261182..262117 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0236; inosine-uridine preferring nucleoside hydrolase 262117 2864144 SAS0219 Staphylococcus aureus subsp. aureus MSSA476 inosine-uridine preferring nucleoside hydrolase YP_042341.1 261182 D 282459 CDS YP_042342.1 49485121 2864188 262153..262323 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0237; No significant database hits; hypothetical protein 262323 2864188 SAS0219a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042342.1 262153 D 282459 CDS YP_042343.1 49485122 2864189 262433..264550 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0238; PTS regulator 264550 2864189 SAS0220 Staphylococcus aureus subsp. aureus MSSA476 PTS regulator YP_042343.1 262433 D 282459 CDS YP_042344.1 49485123 2864206 264535..265002 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0240; PTS transport system, IIA component 265002 2864206 SAS0221 Staphylococcus aureus subsp. aureus MSSA476 PTS transport system, IIA component YP_042344.1 264535 D 282459 CDS YP_042345.1 49485124 2864207 265025..265303 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0241; PTS transport system, IIB component 265303 2864207 SAS0222 Staphylococcus aureus subsp. aureus MSSA476 PTS transport system, IIB component YP_042345.1 265025 D 282459 CDS YP_042346.1 49485125 2864187 265530..266789 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0242; PTS transport system, IIC component 266789 2864187 SAS0223 Staphylococcus aureus subsp. aureus MSSA476 PTS transport system, IIC component YP_042346.1 265530 D 282459 CDS YP_042347.1 49485126 2862222 266807..267862 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0243; zinc-binding dehydrogenase 267862 2862222 SAS0224 Staphylococcus aureus subsp. aureus MSSA476 zinc-binding dehydrogenase YP_042347.1 266807 D 282459 CDS YP_042348.1 49485127 2862223 267864..268010 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0244; hypothetical protein 268010 2862223 SAS0225 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042348.1 267864 D 282459 CDS YP_042349.1 49485128 2862303 268034..269077 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0245; zinc-binding dehydrogenase 269077 2862303 SAS0226 Staphylococcus aureus subsp. aureus MSSA476 zinc-binding dehydrogenase YP_042349.1 268034 D 282459 CDS YP_042350.1 49485129 2861974 269605..270321 1 NC_002953.3 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 270321 ispD 2861974 ispD Staphylococcus aureus subsp. aureus MSSA476 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_042350.1 269605 D 282459 CDS YP_042351.1 49485130 2861975 270314..271339 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0247; zinc-binding dehydrogenase 271339 2861975 SAS0228 Staphylococcus aureus subsp. aureus MSSA476 zinc-binding dehydrogenase YP_042351.1 270314 D 282459 CDS YP_042352.1 49485131 2861966 271361..273055 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0248; hypothetical protein 273055 2861966 SAS0229 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042352.1 271361 D 282459 CDS YP_042353.1 49485132 2862596 complement(273367..273501) 1 NC_002953.3 No significant database matches. Doubtful CDS; hypothetical protein 273501 2862596 SAS0230 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042353.1 273367 R 282459 CDS YP_042354.1 49485133 2862873 273703..273828 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0250; No significant database matches. Doubtful CDS; hypothetical protein 273828 2862873 SAS0230a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042354.1 273703 D 282459 CDS YP_042355.1 49485134 2862545 274081..275250 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0251; teichoic acid biosynthesis protein 275250 2862545 SAS0231 Staphylococcus aureus subsp. aureus MSSA476 teichoic acid biosynthesis protein YP_042355.1 274081 D 282459 CDS YP_042356.1 49485135 2862546 275526..276242 1 NC_002953.3 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 276242 ispD 2862546 ispD Staphylococcus aureus subsp. aureus MSSA476 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_042356.1 275526 D 282459 CDS YP_042357.1 49485136 2862002 276235..277260 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0253; zinc-binding dehydrogenase 277260 2862002 SAS0233 Staphylococcus aureus subsp. aureus MSSA476 zinc-binding dehydrogenase YP_042357.1 276235 D 282459 CDS YP_042358.1 49485137 2862721 277282..278970 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0254; hypothetical protein 278970 2862721 SAS0234 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042358.1 277282 D 282459 CDS YP_042359.1 49485138 2862722 279003..280724 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0255; glycosyl transferase family protein 280724 2862722 SAS0235 Staphylococcus aureus subsp. aureus MSSA476 glycosyl transferase family protein YP_042359.1 279003 D 282459 CDS YP_042360.1 49485139 2864369 280868..281542 1 NC_002953.3 involved in peptidoglycan cross-linking; cell wall biosynthesis protein ScdA 281542 2864369 SAS0236 Staphylococcus aureus subsp. aureus MSSA476 cell wall biosynthesis protein ScdA YP_042360.1 280868 D 282459 CDS YP_042361.1 49485140 2863410 281786..283540 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0257; autolysin sensor kinase 283540 2863410 SAS0237 Staphylococcus aureus subsp. aureus MSSA476 autolysin sensor kinase YP_042361.1 281786 D 282459 CDS YP_042362.1 49485141 2863411 283543..284283 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0258; two-component response regulator 284283 2863411 SAS0238 Staphylococcus aureus subsp. aureus MSSA476 two-component response regulator YP_042362.1 283543 D 282459 CDS YP_042363.1 49485142 2862404 284396..284839 1 NC_002953.3 negatively regulates murein hydrolase activity; murein hydrolase regulator LrgA 284839 2862404 SAS0239 Staphylococcus aureus subsp. aureus MSSA476 murein hydrolase regulator LrgA YP_042363.1 284396 D 282459 CDS YP_042364.1 49485143 2864274 284832..285533 1 NC_002953.3 in conjunction with LrgA this protein inhibits the expression or activity of extracellular murein hydrolases; antiholin-like protein LrgB 285533 2864274 SAS0240 Staphylococcus aureus subsp. aureus MSSA476 antiholin-like protein LrgB YP_042364.1 284832 D 282459 CDS YP_042365.1 49485144 2864275 complement(285641..286345) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0262; GntR family transcriptional regulator 286345 2864275 SAS0241 Staphylococcus aureus subsp. aureus MSSA476 GntR family transcriptional regulator YP_042365.1 285641 R 282459 CDS YP_042366.1 49485145 2864277 286494..287285 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0263; PTS transport system protein 287285 2864277 SAS0242 Staphylococcus aureus subsp. aureus MSSA476 PTS transport system protein YP_042366.1 286494 D 282459 CDS YP_042367.1 49485146 2864278 287301..288737 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0264; 6-phospho-beta-glucosidase 288737 2864278 SAS0243 Staphylococcus aureus subsp. aureus MSSA476 6-phospho-beta-glucosidase YP_042367.1 287301 D 282459 CDS YP_042368.1 49485147 2864276 complement(289230..289991) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0265; hypothetical protein 289991 2864276 SAS0244 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042368.1 289230 R 282459 CDS YP_042369.1 49485148 2863621 complement(290242..291156) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0266; ribokinase 291156 2863621 SAS0245 Staphylococcus aureus subsp. aureus MSSA476 ribokinase YP_042369.1 290242 R 282459 CDS YP_042370.1 49485149 2863622 complement(291184..291588) 1 NC_002953.3 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 291588 2863622 SAS0246 Staphylococcus aureus subsp. aureus MSSA476 D-ribose pyranase YP_042370.1 291184 R 282459 CDS YP_042371.1 49485150 2863998 complement(291603..292484) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0268; sugar transport protein 292484 2863998 SAS0247 Staphylococcus aureus subsp. aureus MSSA476 sugar transport protein YP_042371.1 291603 R 282459 CDS YP_042372.1 49485151 2863794 complement(292716..293714) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0269; LacI family regulatory protein 293714 2863794 SAS0248 Staphylococcus aureus subsp. aureus MSSA476 LacI family regulatory protein YP_042372.1 292716 R 282459 CDS YP_042373.1 49485152 2863795 293932..294045 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0269a; No significant database matches. Doubtful CDS; hypothetical protein 294045 2863795 SAS0248a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042373.1 293932 D 282459 CDS YP_042374.1 49485153 2863781 294095..294487 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0270; hypothetical protein 294487 2863781 SAS0249 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042374.1 294095 D 282459 CDS YP_042375.1 49485154 2863099 complement(294615..295991) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0271; transport protein 295991 2863099 SAS0250 Staphylococcus aureus subsp. aureus MSSA476 transport protein YP_042375.1 294615 R 282459 CDS YP_042376.1 49485155 2863100 296225..297217 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0272; choloylglycine hydrolase 297217 2863100 SAS0251 Staphylococcus aureus subsp. aureus MSSA476 choloylglycine hydrolase YP_042376.1 296225 D 282459 CDS YP_042377.1 49485156 2863939 297543..298493 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0273; peptidoglycan hydrolase 298493 2863939 SAS0252 Staphylococcus aureus subsp. aureus MSSA476 peptidoglycan hydrolase YP_042377.1 297543 D 282459 CDS YP_042378.1 49485157 2863940 complement(298545..299204) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0274; ABC transporter ATP-binding protein 299204 2863940 SAS0253 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042378.1 298545 R 282459 CDS YP_042379.1 49485158 2862814 complement(299218..300138) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0275; hypothetical protein 300138 2862814 SAS0254 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042379.1 299218 R 282459 CDS YP_042380.1 49485159 2863689 complement(300135..301301) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0276; hypothetical protein 301301 2863689 SAS0255 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042380.1 300135 R 282459 CDS YP_042381.1 49485160 2863690 complement(301369..302892) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0277; hypothetical protein 302892 2863690 SAS0256 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042381.1 301369 R 282459 CDS YP_042382.1 49485161 2863691 complement(303223..304125) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0278; hypothetical protein 304125 2863691 SAS0257 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042382.1 303223 R 282459 CDS YP_042383.1 49485162 2862396 304364..304657 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0279; hypothetical protein 304657 2862396 SAS0258 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042383.1 304364 D 282459 CDS YP_042384.1 49485163 2862397 304740..307769 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0280; hypothetical protein 307769 2862397 SAS0259 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042384.1 304740 D 282459 CDS YP_042385.1 49485164 2864258 307769..308227 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0281; hypothetical protein 308227 2864258 SAS0260 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042385.1 307769 D 282459 CDS YP_042386.1 49485165 2864259 308199..308441 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0282; hypothetical protein 308441 2864259 SAS0261 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042386.1 308199 D 282459 CDS YP_042387.1 49485166 2863608 308454..309788 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0283; hypothetical protein 309788 2863608 SAS0262 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042387.1 308454 D 282459 CDS YP_042388.1 49485167 2863774 309810..314249 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0284; hypothetical protein 314249 2863774 SAS0263 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042388.1 309810 D 282459 CDS YP_042389.1 49485168 2863775 314279..314671 1 NC_002953.3 hypothetical protein 314671 2863775 SAS0264 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042389.1 314279 D 282459 CDS YP_042390.1 49485169 2862297 314687..315001 1 NC_002953.3 Similar to Listeria monocytogenes hypothetical protein lmo0063 SWALL:Q8YAQ4 (EMBL:AL591973) (99 aa) fasta scores: E(): 0.01, 22.91% id in 96 aa, and to Listeria innocua hypothetical protein lin0056 SWALL:Q92FP7 (EMBL:AL596163) (99 aa) fasta scores: E(): 0.014, 22.91% id in 96 aa; hypothetical protein 315001 2862297 SAS0265 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042390.1 314687 D 282459 CDS YP_042391.1 49485170 2863875 314998..315675 1 NC_002953.3 Similar to Listeria monocytogenes hypothetical protein lmo0064 SWALL:Q8YAQ3 (EMBL:AL591973) (233 aa) fasta scores: E(): 0.066, 22.89% id in 214 aa, and to Listeria innocua hypothetical protein lin0057 SWALL:Q92FP6 (EMBL:AL596163) (233 aa) fasta scores: E(): 0.39, 21.69% id in 212 aa; hypothetical protein 315675 2863875 SAS0266 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042391.1 314998 D 282459 CDS YP_042392.1 49485171 2863876 315675..315992 1 NC_002953.3 hypothetical protein 315992 2863876 SAS0267 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042392.1 315675 D 282459 CDS YP_042393.1 49485172 2862220 316002..317846 1 NC_002953.3 Weakly similar to Listeria monocytogenes hypothetical protein lmo0066 SWALL:Q8YAQ1 (EMBL:AL591973) (604 aa) fasta scores: E(): 2.1e-11, 22.54% id in 630 aa; hypothetical protein 317846 2862220 SAS0268 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042393.1 316002 D 282459 CDS YP_042394.1 49485173 2862221 317857..318351 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0293; hypothetical protein 318351 2862221 SAS0269 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042394.1 317857 D 282459 CDS YP_042395.1 49485174 2863933 318562..319245 1 NC_002953.3 hypothetical protein 319245 2863933 SAS0270 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042395.1 318562 D 282459 CDS YP_042396.1 49485175 2861838 319392..320003 1 NC_002953.3 hypothetical protein 320003 2861838 SAS0271 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042396.1 319392 D 282459 CDS YP_042397.1 49485176 2861839 320202..320702 1 NC_002953.3 Similar to Bacillus cereus hypothetical cytosolic protein bc3263 SWALL:Q813D5 (EMBL:AE017008) (173 aa) fasta scores: E(): 8.5e-11, 31.41% id in 156 aa, and to the C-terminal region of Bacillus subtilis hypothetical cytosolic protein YeeE SWALL:O30580 (EMBL:AF012532) (369 aa) fasta scores: E(): 1.4e-11, 28.76% id in 146 aa; hypothetical protein 320702 2861839 SAS0272 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042397.1 320202 D 282459 CDS YP_042398.1 49485177 2863897 320713..321213 1 NC_002953.3 Similar to Bacillus halodurans hypothetical protein bh3703 SWALL:Q9K6M5 (EMBL:AP001519) (169 aa) fasta scores: E(): 2e-07, 30.06% id in 163 aa, and to the C-terminal region of Bacillus subtilis hypothetical protein YeeE SWALL:O30580 (EMBL:AF012532) (369 aa) fasta scores: E(): 5.8e-11, 30.13% id in 146 aa; hypothetical protein 321213 2863897 SAS0273 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042398.1 320713 D 282459 CDS YP_042399.1 49485178 2863936 321224..321724 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0294; Similar to Bacillus cereus hypothetical cytosolic protein bc3263 SWALL:Q813D5 (EMBL:AE017008) (173 aa) fasta scores: E(): 2.8e-13, 36.02% id in 161 aa, and to the C-terminal region of Bacillus subtilis hypothetical protein YeeE SWALL:O30580 (EMBL:AF012532) (369 aa) fasta scores: E(): 3.5e-13, 32.85% id in 140 aa; hypothetical protein 321724 2863936 SAS0274 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042399.1 321224 D 282459 CDS YP_042400.1 49485179 2863937 321735..322235 1 NC_002953.3 Similar to Bacillus cereus hypothetical cytosolic protein bc3263 SWALL:Q813D5 (EMBL:AE017008) (173 aa) fasta scores: E(): 4e-10, 30.51% id in 154 aa, and to the C-terminal region Bacillus subtilis hypothetical protein YeeE SWALL:O30580 (EMBL:AF012532) (369 aa) fasta scores: E(): 3.5e-09, 27.33% id in 150 aa; hypothetical protein 322235 2863937 SAS0275 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042400.1 321735 D 282459 CDS YP_042401.1 49485180 2862839 322246..322746 1 NC_002953.3 Similar to Bacillus cereus hypothetical cytosolic protein bc3263 SWALL:Q813D5 (EMBL:AE017008) (173 aa) fasta scores: E(): 1e-10, 33.11% id in 154 aa, and to the C-terminal region of Bacillus subtilis hypothetical protein YeeE SWALL:O30580 (EMBL:AF012532) (369 aa) fasta scores: E(): 9.4e-11, 30.71% id in 140 aa; hypothetical protein 322746 2862839 SAS0276 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042401.1 322246 D 282459 CDS YP_042402.1 49485181 2862840 322757..323257 1 NC_002953.3 Similar to Bacillus cereus hypothetical cytosolic protein bc3263 SWALL:Q813D5 (EMBL:AE017008) (173 aa) fasta scores: E(): 2.8e-14, 37.01% id in 154 aa, and to the C-terminal region of Bacillus subtilis hypothetical protein YeeE SWALL:O30580 (EMBL:AF012532) (369 aa) fasta scores: E(): 3.3e-12, 32.14% id in 140 aa; hypothetical protein 323257 2862840 SAS0277 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042402.1 322757 D 282459 CDS YP_042403.1 49485182 2861844 323268..323768 1 NC_002953.3 Similar to Bacillus cereus hypothetical cytosolic protein bc3263 SWALL:Q813D5 (EMBL:AE017008) (173 aa) fasta scores: E(): 1.3e-10, 33.11% id in 154 aa, and to the C-terminal region of Bacillus subtilis YeeE SWALL:O30580 (EMBL:AF012532) (369 aa) fasta scores: E(): 3.1e-11, 31.42% id in 140 aa; hypothetical protein 323768 2861844 SAS0278 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042403.1 323268 D 282459 CDS YP_042404.1 49485183 2863902 323779..324267 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0297; Similar to Bacillus cereus hypothetical cytosolic protein bc3263 SWALL:Q813D5 (EMBL:AE017008) (173 aa) fasta scores: E(): 1.8e-12, 33.33% id in 156 aa, and to the C-terminal region of Bacillus subtilis YeeE SWALL:O30580 (EMBL:AF012532) (369 aa) fasta scores: E(): 1.4e-11, 29.45% id in 146 aa; hypothetical protein 324267 2863902 SAS0279 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042404.1 323779 D 282459 CDS YP_042405.1 49485184 2863903 324892..325266 1 NC_002953.3 Poor database matches. Weakly similar to Clostridium tetani hypothetical protein ctc00500 SWALL:Q898F5 (EMBL:AE015937) (145 aa) fasta scores: E(): 0.27, 26.98% id in 126 aa; hypothetical protein 325266 2863903 SAS0280 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042405.1 324892 D 282459 CDS YP_042406.1 49485185 2862065 325416..325814 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0301; hypothetical protein 325814 2862065 SAS0281 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042406.1 325416 D 282459 CDS YP_042407.1 49485186 2862040 complement(326064..326888) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0302; formate/nitrite transporter 326888 2862040 SAS0282 Staphylococcus aureus subsp. aureus MSSA476 formate/nitrite transporter YP_042407.1 326064 R 282459 CDS YP_042408.1 49485187 2862041 complement(327127..328434) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0303; amino acid transport system 328434 2862041 SAS0283 Staphylococcus aureus subsp. aureus MSSA476 amino acid transport system YP_042408.1 327127 R 282459 CDS YP_042409.1 49485188 2862075 329018..329908 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0304; hypothetical protein 329908 2862075 SAS0284 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042409.1 329018 D 282459 CDS YP_042410.1 49485189 2862076 330158..331207 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0305; hypothetical protein 331207 2862076 SAS0285 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042410.1 330158 D 282459 CDS YP_042411.1 49485190 2862084 331220..331897 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0306; ABC transporter ATP-binding protein 331897 2862084 SAS0286 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042411.1 331220 D 282459 CDS YP_042412.1 49485191 2863796 332105..333136 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0307; hypothetical protein 333136 2863796 SAS0287 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042412.1 332105 D 282459 CDS YP_042413.1 49485192 2863797 333479..334597 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0308; PfkB family carbohydrate kinase 334597 2863797 SAS0288 Staphylococcus aureus subsp. aureus MSSA476 PfkB family carbohydrate kinase YP_042413.1 333479 D 282459 CDS YP_042414.1 49485193 2861857 334572..335495 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0309; hypothetical protein 335495 2861857 SAS0289 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042414.1 334572 D 282459 CDS YP_042415.1 49485194 2863109 335506..336726 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0310; nucleoside permease 336726 2863109 SAS0290 Staphylococcus aureus subsp. aureus MSSA476 nucleoside permease YP_042415.1 335506 D 282459 CDS YP_042416.1 49485195 2863110 complement(336832..338364) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0311; sodium:solute symporter family protein 338364 2863110 SAS0291 Staphylococcus aureus subsp. aureus MSSA476 sodium:solute symporter family protein YP_042416.1 336832 R 282459 CDS YP_042417.1 49485196 2861853 complement(338404..339285) 1 NC_002953.3 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 339285 2861853 SAS0292 Staphylococcus aureus subsp. aureus MSSA476 N-acetylneuraminate lyase YP_042417.1 338404 R 282459 CDS YP_042418.1 49485197 2861854 339443..340303 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0313; ROK family protein 340303 2861854 SAS0293 Staphylococcus aureus subsp. aureus MSSA476 ROK family protein YP_042418.1 339443 D 282459 CDS YP_042419.1 49485198 2863832 complement(340580..341380) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0314; hypothetical protein 341380 2863832 SAS0294 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042419.1 340580 R 282459 CDS YP_042420.1 49485199 2863200 341521..342189 1 NC_002953.3 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 342189 2863200 SAS0295 Staphylococcus aureus subsp. aureus MSSA476 N-acetylmannosamine-6-phosphate 2-epimerase YP_042420.1 341521 D 282459 CDS YP_042421.1 49485200 2863201 complement(342320..343633) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0316; hypothetical protein 343633 2863201 SAS0296 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042421.1 342320 R 282459 CDS YP_042422.1 49485201 2862193 344051..346123 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0317; lipase precursor 346123 2862193 SAS0297 Staphylococcus aureus subsp. aureus MSSA476 lipase precursor YP_042422.1 344051 D 282459 CDS YP_042423.1 49485202 2863188 complement(346365..347192) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0318; hypothetical protein 347192 2863188 SAS0298 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042423.1 346365 R 282459 CDS YP_042424.1 49485203 2863189 complement(347265..348464) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0319; NADH:flavin oxidoreductase / NADH oxidase family protein 348464 2863189 SAS0299 Staphylococcus aureus subsp. aureus MSSA476 NADH:flavin oxidoreductase / NADH oxidase family protein YP_042424.1 347265 R 282459 CDS YP_042425.1 49485204 2863855 348766..349767 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0320; luciferase family protein 349767 2863855 SAS0300 Staphylococcus aureus subsp. aureus MSSA476 luciferase family protein YP_042425.1 348766 D 282459 CDS YP_042426.1 49485205 2863856 349801..350133 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0321; glycine cleavage H-protein 350133 2863856 SAS0301 Staphylococcus aureus subsp. aureus MSSA476 glycine cleavage H-protein YP_042426.1 349801 D 282459 CDS YP_042427.1 49485206 2862430 350134..350934 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0322; hypothetical protein 350934 2862430 SAS0302 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042427.1 350134 D 282459 CDS YP_042428.1 49485207 2863326 350921..351868 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0323; hypothetical protein 351868 2863326 SAS0303 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042428.1 350921 D 282459 CDS YP_042429.1 49485208 2863327 351846..352868 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0324; lipoate-protein ligase A 352868 2863327 SAS0304 Staphylococcus aureus subsp. aureus MSSA476 lipoate-protein ligase A YP_042429.1 351846 D 282459 CDS YP_042430.1 49485209 2862446 353181..354209 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0325; reductase 354209 2862446 SAS0305 Staphylococcus aureus subsp. aureus MSSA476 reductase YP_042430.1 353181 D 282459 CDS YP_042431.1 49485210 2862975 complement(354302..355648) 1 NC_002953.3 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 355648 ulaA 2862975 ulaA Staphylococcus aureus subsp. aureus MSSA476 PTS system ascorbate-specific transporter subunit IIC YP_042431.1 354302 R 282459 CDS YP_042432.1 49485211 2862976 complement(355663..355947) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0327; PTS transport system protein 355947 2862976 SAS0307 Staphylococcus aureus subsp. aureus MSSA476 PTS transport system protein YP_042432.1 355663 R 282459 CDS YP_042433.1 49485212 2862894 complement(355949..356392) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0328; PTS transport system IIA component 356392 2862894 SAS0308 Staphylococcus aureus subsp. aureus MSSA476 PTS transport system IIA component YP_042433.1 355949 R 282459 CDS YP_042434.1 49485213 2862895 complement(356397..358352) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0329; PTS regulator 358352 2862895 SAS0309 Staphylococcus aureus subsp. aureus MSSA476 PTS regulator YP_042434.1 356397 R 282459 CDS YP_042435.1 49485214 2862954 358564..358983 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0330; MarR family transcriptional regulator 358983 2862954 SAS0310 Staphylococcus aureus subsp. aureus MSSA476 MarR family transcriptional regulator YP_042435.1 358564 D 282459 CDS YP_042436.1 49485215 2862978 359090..360445 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0331; hypothetical protein 360445 2862978 SAS0311 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042436.1 359090 D 282459 CDS YP_042437.1 49485216 2862979 360552..360992 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0332; hypothetical protein 360992 2862979 SAS0312 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042437.1 360552 D 282459 CDS YP_042438.1 49485217 2862947 complement(361075..362433) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0333; glycerol-3-phosphate transporter 362433 2862947 SAS0313 Staphylococcus aureus subsp. aureus MSSA476 glycerol-3-phosphate transporter YP_042438.1 361075 R 282459 CDS YP_042439.1 49485218 2862980 362745..363671 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0334; dioxygenase 363671 2862980 SAS0314 Staphylococcus aureus subsp. aureus MSSA476 dioxygenase YP_042439.1 362745 D 282459 CDS YP_042440.1 49485219 2862981 363685..364746 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0335; luciferase-like monooxygenase 364746 2862981 SAS0315 Staphylococcus aureus subsp. aureus MSSA476 luciferase-like monooxygenase YP_042440.1 363685 D 282459 CDS YP_042441.1 49485220 2863000 364760..365326 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0336; NADH-dependent FMN reductase 365326 2863000 SAS0316 Staphylococcus aureus subsp. aureus MSSA476 NADH-dependent FMN reductase YP_042441.1 364760 D 282459 CDS YP_042442.1 49485221 2863001 complement(365386..366381) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0338; hypothetical protein 366381 2863001 SAS0317 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042442.1 365386 R 282459 CDS YP_042443.1 49485222 2862958 366686..367231 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0339; acetyltransferase 367231 2862958 SAS0318 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase YP_042443.1 366686 D 282459 CDS YP_042444.1 49485223 2863008 367498..368352 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0340; lipoprotein 368352 2863008 SAS0319 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_042444.1 367498 D 282459 CDS YP_042445.1 49485224 2863009 368349..369578 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0341; Sec-independent exported protein 369578 2863009 SAS0320 Staphylococcus aureus subsp. aureus MSSA476 Sec-independent exported protein YP_042445.1 368349 D 282459 CDS YP_042446.1 49485225 2861817 369556..371271 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0342; hypothetical protein 371271 2861817 SAS0321 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042446.1 369556 D 282459 CDS YP_042447.1 49485226 2862111 complement(371363..372064) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0343; Sec-independent protein translocase 372064 2862111 SAS0322 Staphylococcus aureus subsp. aureus MSSA476 Sec-independent protein translocase YP_042447.1 371363 R 282459 CDS YP_042448.1 49485227 2862112 complement(372081..372296) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0344; Sec-independent protein translocase 372296 2862112 SAS0323 Staphylococcus aureus subsp. aureus MSSA476 Sec-independent protein translocase YP_042448.1 372081 R 282459 CDS YP_042449.1 49485228 2861795 complement(372404..372793) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0345; hypothetical protein 372793 2861795 SAS0324 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042449.1 372404 R 282459 CDS YP_042450.1 49485229 2861796 373033..373236 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0346; DNA-binding protein 373236 2861796 SAS0325 Staphylococcus aureus subsp. aureus MSSA476 DNA-binding protein YP_042450.1 373033 D 282459 CDS YP_042451.1 49485230 2863010 373233..373946 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0347; hypothetical protein 373946 2863010 SAS0326 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042451.1 373233 D 282459 CDS YP_042452.1 49485231 2864421 373971..374813 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0348; ABC transporter ATP-binding protein 374813 2864421 SAS0327 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042452.1 373971 D 282459 CDS YP_042453.1 49485232 2864422 374813..375442 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0349; hypothetical protein 375442 2864422 SAS0328 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042453.1 374813 D 282459 CDS YP_042454.1 49485233 2864401 complement(375832..376965) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0350; hypothetical protein 376965 2864401 SAS0329 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042454.1 375832 R 282459 CDS YP_042455.1 49485234 2864409 377504..378685 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0351; acetyl-CoA acetyltransferase 378685 2864409 SAS0330 Staphylococcus aureus subsp. aureus MSSA476 acetyl-CoA acetyltransferase YP_042455.1 377504 D 282459 CDS YP_042456.1 49485235 2864410 complement(378768..379520) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0352; hypothetical protein 379520 2864410 SAS0331 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042456.1 378768 R 282459 CDS YP_042457.1 49485236 2862696 complement(379563..381791) 1 NC_002953.3 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 381791 2862696 SAS0332 Staphylococcus aureus subsp. aureus MSSA476 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_042457.1 379563 R 282459 CDS YP_042458.1 49485237 2862697 complement(381788..383629) 1 NC_002953.3 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase 383629 2862697 SAS0333 Staphylococcus aureus subsp. aureus MSSA476 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase YP_042458.1 381788 R 282459 CDS YP_042459.1 49485238 2863999 complement(383598..384758) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0355; Cys/Met metabolism PLP-dependent enzyme 384758 2863999 SAS0334 Staphylococcus aureus subsp. aureus MSSA476 Cys/Met metabolism PLP-dependent enzyme YP_042459.1 383598 R 282459 CDS YP_042460.1 49485239 2863306 complement(384755..385858) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0356; Cys/Met metabolism PLP-dependent enzyme 385858 2863306 SAS0335 Staphylococcus aureus subsp. aureus MSSA476 Cys/Met metabolism PLP-dependent enzyme YP_042460.1 384755 R 282459 CDS YP_042461.1 49485240 2863307 386522..387367 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0357; DNA-binding protein 387367 2863307 SAS0336 Staphylococcus aureus subsp. aureus MSSA476 DNA-binding protein YP_042461.1 386522 D 282459 CDS YP_042462.1 49485241 2863262 387524..388405 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0358; hypothetical protein 388405 2863262 SAS0337 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042462.1 387524 D 282459 CDS YP_042463.1 49485242 2863445 388435..388638 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0359; hypothetical protein 388638 2863445 SAS0338 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042463.1 388435 D 282459 CDS YP_042464.1 49485243 2863446 388650..389747 1 NC_002953.3 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 389747 2863446 SAS0339 Staphylococcus aureus subsp. aureus MSSA476 GTP-dependent nucleic acid-binding protein EngD YP_042464.1 388650 D 282459 CDS YP_042465.1 49485244 2862650 complement(389833..390024) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0361; hypothetical protein 390024 2862650 SAS0340 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042465.1 389833 R 282459 CDS YP_042466.1 49485245 2862651 390268..390564 1 NC_002953.3 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 390564 rpsF 2862651 rpsF Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S6 YP_042466.1 390268 D 282459 CDS YP_042467.1 49485246 2863484 390585..391088 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0363; single-strand DNA-binding protein 391088 2863484 SAS0342 Staphylococcus aureus subsp. aureus MSSA476 single-strand DNA-binding protein YP_042467.1 390585 D 282459 CDS YP_042468.1 49485247 2862603 391140..391382 1 NC_002953.3 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 391382 rpsR 2862603 rpsR Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S18 YP_042468.1 391140 D 282459 CDS YP_042469.1 49485248 2862604 complement(391648..392640) 1 NC_002953.3 N-terminal region is similar to Bacillus anthracis hypothetical protein bxa0052 SWALL:Q9X309 (EMBL:AF065404) (276 aa) fasta scores: E(): 1.7e-11, 38.26% id in 230 aa, and to the N-terminal region of Enterococcus faecalis hypothetical protein ef2085 SWALL:Q832Y3 (EMBL:AE016953) (322 aa) fasta scores: E(): 0.0034, 26.37% id in 273 aa; hypothetical protein 392640 2862604 SAS0344 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042469.1 391648 R 282459 CDS YP_042470.1 49485249 2862621 393545..394156 1 NC_002953.3 Poor database matches. C-terminus is similar to the C-terminal region of Staphylococcus aureus exotoxin 1 Set1 SWALL:Q9RN32 (EMBL:AF188837) (231 aa) fasta scores: E(): 0.034, 30.92% id in 152 aa; hypothetical protein 394156 2862621 SAS0347 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042470.1 393545 D 282459 CDS YP_042471.1 49485250 2862622 394525..394926 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0389; hypothetical protein 394926 2862622 SAS0348 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042471.1 394525 D 282459 CDS YP_042472.1 49485251 2864124 395074..395646 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0390; hypothetical protein 395646 2864124 SAS0349 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042472.1 395074 D 282459 CDS YP_042473.1 49485252 2864125 complement(395784..396047) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0391; hypothetical protein 396047 2864125 SAS0350 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042473.1 395784 R 282459 CDS YP_042474.1 49485253 2864078 396341..396592 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0392; hypothetical protein 396592 2864078 SAS0351 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042474.1 396341 D 282459 CDS YP_042475.1 49485254 2864058 complement(396631..396840) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0393; hypothetical protein 396840 2864058 SAS0352 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042475.1 396631 R 282459 CDS YP_042476.1 49485255 2864059 397018..397599 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0394; phosphoglycerate mutase family protein 397599 2864059 SAS0353 Staphylococcus aureus subsp. aureus MSSA476 phosphoglycerate mutase family protein YP_042476.1 397018 D 282459 CDS YP_042477.1 49485256 2864291 complement(397665..398048) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0395; hypothetical protein 398048 2864291 SAS0354 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042477.1 397665 R 282459 CDS YP_042478.1 49485257 2863220 398136..398234 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR395a; No significant database matches. Doubtful CDS; hypothetical protein 398234 2863220 SAS0354a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042478.1 398136 D 282459 CDS YP_042479.1 49485258 2863221 complement(398303..398929) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0396; hypothetical protein 398929 2863221 SAS0355 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042479.1 398303 R 282459 CDS YP_042480.1 49485259 2864303 complement(399002..400612) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0397; hypothetical protein 400612 2864303 SAS0356 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042480.1 399002 R 282459 CDS YP_042481.1 49485260 2864304 complement(400727..402250) 1 NC_002953.3 EC_number 1.6.4.-; Ortholog of S. aureus MRSA252 (BX571856) SAR0398; alkyl hydroperoxide reductase 402250 2864304 SAS0357 Staphylococcus aureus subsp. aureus MSSA476 alkyl hydroperoxide reductase YP_042481.1 400727 R 282459 CDS YP_042482.1 49485261 2864225 complement(402266..402835) 1 NC_002953.3 EC_number 1.6.4.-; Ortholog of S. aureus MRSA252 (BX571856) SAR0399; alkyl hydroperoxide reductase 402835 2864225 SAS0358 Staphylococcus aureus subsp. aureus MSSA476 alkyl hydroperoxide reductase YP_042482.1 402266 R 282459 CDS YP_042483.1 49485262 2864100 403327..404082 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0400; nitroreductase family protein 404082 2864100 SAS0359 Staphylococcus aureus subsp. aureus MSSA476 nitroreductase family protein YP_042483.1 403327 D 282459 CDS YP_042484.1 49485263 2864101 complement(404163..405551) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0401; sodium:dicarboxylate symporter protein 405551 2864101 SAS0360 Staphylococcus aureus subsp. aureus MSSA476 sodium:dicarboxylate symporter protein YP_042484.1 404163 R 282459 CDS YP_042485.1 49485264 2864127 405636..405734 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0401a; No significant database matches. Doubtful CDS; hypothetical protein 405734 2864127 SAS0360a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042485.1 405636 D 282459 CDS YP_042486.1 49485265 2862261 complement(406725..407681) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0403; hypothetical protein 407681 2862261 SAS0361 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042486.1 406725 R 282459 CDS YP_042487.1 49485266 2862262 complement(407799..408461) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0404; hypothetical protein 408461 2862262 SAS0362 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042487.1 407799 R 282459 CDS YP_042488.1 49485267 2862245 complement(408604..409011) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0405; hypothetical protein 409011 2862245 SAS0363 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042488.1 408604 R 282459 CDS YP_042489.1 49485268 2862246 409524..410102 1 NC_002953.3 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 410102 2862246 SAS0364 Staphylococcus aureus subsp. aureus MSSA476 xanthine phosphoribosyltransferase YP_042489.1 409524 D 282459 CDS YP_042490.1 49485269 2864194 410102..411370 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0407; xanthine permease 411370 2864194 SAS0365 Staphylococcus aureus subsp. aureus MSSA476 xanthine permease YP_042490.1 410102 D 282459 CDS YP_042491.1 49485270 2862240 411408..412874 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0408; inosine-5'-monophosphate dehydrogenase 412874 2862240 SAS0366 Staphylococcus aureus subsp. aureus MSSA476 inosine-5'-monophosphate dehydrogenase YP_042491.1 411408 D 282459 CDS YP_042492.1 49485271 2862241 412899..414440 1 NC_002953.3 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 414440 guaA 2862241 guaA Staphylococcus aureus subsp. aureus MSSA476 GMP synthase YP_042492.1 412899 D 282459 CDS YP_042493.1 49485272 2862316 414952..416058 1 NC_002953.3 hypothetical protein 416058 2862316 SAS0368 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042493.1 414952 D 282459 CDS YP_042494.1 49485273 2861983 416502..416687 1 NC_002953.3 Poor database matches. Weakly similar to the C-terminal region of Buchnera aphidicola high-affinity zinc uptake system membrane protein bbp294 SWALL:Q89AJ1 (EMBL:AE014017) (261 aa) fasta scores: E(): 4.7, 35.41% id in 48 aa; hypothetical protein 416687 2861983 SAS0369 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042494.1 416502 D 282459 CDS YP_042495.1 49485274 2861984 complement(416684..417076) 1 NC_002953.3 hypothetical protein 417076 2861984 SAS0370 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042495.1 416684 R 282459 CDS YP_042496.1 49485275 2864146 complement(417098..417577) 1 NC_002953.3 hypothetical protein 417577 2864146 SAS0371 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042496.1 417098 R 282459 CDS YP_042497.1 49485276 2864147 complement(417703..417960) 1 NC_002953.3 hypothetical protein 417960 2864147 SAS0372 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042497.1 417703 R 282459 CDS YP_042498.1 49485277 2861952 418503..418835 1 NC_002953.3 Poor database matches. C-terminus is similar to the C-terminal region of Streptococcus mutans hypothetical protein SMU.423 SWALL:Q8DVP7 (EMBL:AE014889) (76 aa) fasta scores: E(): 0.062, 47.54% id in 61 aa; hypothetical protein 418835 2861952 SAS0373 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042498.1 418503 D 282459 CDS YP_042499.1 49485278 2863877 419940..421766 1 NC_002953.3 Poor database matches. Similar to Campylobacter jejuni rloF protein SWALL:Q8G8B7 (EMBL:AF542644) (554 aa) fasta scores: E(): 0.054, 25.08% id in 606 aa; hypothetical protein 421766 2863877 SAS0375 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042499.1 419940 D 282459 CDS YP_042500.1 49485279 2863878 complement(422304..422726) 1 NC_002953.3 Weakly similar to Clostridium perfringens hypothetical protein cpe1491 SWALL:Q8XKA9 (EMBL:AP003190) (140 aa) fasta scores: E(): 1.7, 24.82% id in 141 aa; hypothetical protein 422726 2863878 SAS0376 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042500.1 422304 R 282459 CDS YP_042501.1 49485280 2862013 complement(423051..423599) 1 NC_002953.3 hypothetical protein 423599 2862013 SAS0377 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042501.1 423051 R 282459 CDS YP_042502.1 49485281 2862578 complement(423580..423741) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0418; hypothetical protein 423741 2862578 SAS0378 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042502.1 423580 R 282459 CDS YP_042503.1 49485282 2862579 424095..424502 1 NC_002953.3 Similar to Clostridium tetani conserved protein ctc00602 SWALL:Q897W9 (EMBL:AE015938) (138 aa) fasta scores: E(): 9.2e-11, 41.3% id in 138 aa, and to Bacillus anthracis hypothetical protein ba4379 SWALL:Q81M73 (EMBL:AE017037) (135 aa) fasta scores: E(): 8e-10, 38.97% id in 136 aa; hypothetical protein 424502 2862579 SAS0379 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042503.1 424095 D 282459 CDS YP_042504.1 49485283 2861955 424549..425031 1 NC_002953.3 Similar to Enterococcus faecalis hypothetical protein ef1702 SWALL:Q834F3 (EMBL:AE016952) (154 aa) fasta scores: E(): 1.9e-27, 58.5% id in 147 aa, and to Bacillus subtilis hypothetical protein YbbK or bsu01720 SWALL:YBBK_BACSU (SWALL:Q45584) (151 aa) fasta scores: E(): 9.4e-25, 53.02% id in 149 aa; hypothetical protein 425031 2861955 SAS0380 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042504.1 424549 D 282459 CDS YP_042505.1 49485284 2861956 425231..425920 1 NC_002953.3 Similar to Neisseria meningitidis hypothetical protein nma2192 or rei1 SWALL:Q9JQX9 (EMBL:AL162758) (219 aa) fasta scores: E(): 1.1e-26, 43.83% id in 219 aa, and to the C-terminal region of Corynebacterium efficiens conserved hypothetical protein ce0348 SWALL:Q8FSN5 (EMBL:AP005215) (281 aa) fasta scores: E(): 7.7e-37, 48.9% id in 229 aa; hypothetical protein 425920 2861956 SAS0381 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042505.1 425231 D 282459 CDS YP_042506.1 49485285 2862033 complement(426094..426201) 1 NC_002953.3 Doubtful CDS. No significant database hits; hypothetical protein 426201 2862033 SAS0381a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042506.1 426094 R 282459 CDS YP_042507.1 49485286 2862538 complement(426195..426554) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0420; hypothetical protein 426554 2862538 SAS0382 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042507.1 426195 R 282459 CDS YP_042508.1 49485287 2862539 complement(426573..427418) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0421; hypothetical protein 427418 2862539 SAS0383 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042508.1 426573 R 282459 CDS YP_042509.1 49485288 2864368 427890..428570 1 NC_002953.3 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 428570 2864368 SAS0384 Staphylococcus aureus subsp. aureus MSSA476 superantigen-like protein YP_042509.1 427890 D 282459 CDS YP_042510.1 49485289 2863408 428856..429551 1 NC_002953.3 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 429551 2863408 SAS0385 Staphylococcus aureus subsp. aureus MSSA476 superantigen-like protein YP_042510.1 428856 D 282459 CDS YP_042511.1 49485290 2863409 429842..430912 1 NC_002953.3 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 430912 2863409 SAS0386 Staphylococcus aureus subsp. aureus MSSA476 superantigen-like protein YP_042511.1 429842 D 282459 CDS YP_042512.1 49485291 2862359 431277..432224 1 NC_002953.3 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 432224 2862359 SAS0387 Staphylococcus aureus subsp. aureus MSSA476 superantigen-like protein YP_042512.1 431277 D 282459 CDS YP_042513.1 49485292 2862360 432588..433292 1 NC_002953.3 SSL5, SET3, SET10; bind P-selectin glycoprotein ligand-1 and inhibit P-selectin-mediated neutrophil rolling along the endothelium; these proteins share structural homology to known superantigens but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 5 433292 2862360 SAS0388 Staphylococcus aureus subsp. aureus MSSA476 superantigen-like protein 5 YP_042513.1 432588 D 282459 CDS YP_042514.1 49485293 2864352 433738..434436 1 NC_002953.3 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 434436 2864352 SAS0389 Staphylococcus aureus subsp. aureus MSSA476 superantigen-like protein YP_042514.1 433738 D 282459 CDS YP_042515.1 49485294 2863499 434858..435553 1 NC_002953.3 SSL7, SET1; blocks IgA-FcR interactions and inhibits complement, leading to increased survival of a sensitive bacterium in blood; superantigen-like protein 7 435553 2863499 SAS0390 Staphylococcus aureus subsp. aureus MSSA476 superantigen-like protein 7 YP_042515.1 434858 D 282459 CDS YP_042516.2 161761283 2863500 435892..436590 1 NC_002953.3 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 436590 2863500 SAS0391 Staphylococcus aureus subsp. aureus MSSA476 superantigen-like protein YP_042516.2 435892 D 282459 CDS YP_042517.1 49485296 2863319 436969..437667 1 NC_002953.3 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 437667 2863319 SAS0392 Staphylococcus aureus subsp. aureus MSSA476 superantigen-like protein YP_042517.1 436969 D 282459 CDS YP_042518.1 49485297 2862333 438026..438709 1 NC_002953.3 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 438709 2862333 SAS0393 Staphylococcus aureus subsp. aureus MSSA476 superantigen-like protein YP_042518.1 438026 D 282459 CDS YP_042519.1 49485298 2862334 438787..438918 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0432; Doubtful CDS. No significant database hits; hypothetical protein 438918 2862334 SAS0393a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042519.1 438787 D 282459 CDS YP_042520.1 49485299 2862833 438971..440527 1 NC_002953.3 restriction enzyme modification protein 440527 2862833 SAS0394 Staphylococcus aureus subsp. aureus MSSA476 restriction enzyme modification protein YP_042520.1 438971 D 282459 CDS YP_042521.1 49485300 2862834 440520..441779 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0434; restriction and modification system specificity protein 441779 2862834 SAS0395 Staphylococcus aureus subsp. aureus MSSA476 restriction and modification system specificity protein YP_042521.1 440520 D 282459 CDS YP_042522.1 49485301 2862387 442185..442877 1 NC_002953.3 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 442877 2862387 SAS0396 Staphylococcus aureus subsp. aureus MSSA476 superantigen-like protein YP_042522.1 442185 D 282459 CDS YP_042523.1 49485302 2863762 442899..444401 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0436; hypothetical protein 444401 2863762 SAS0397 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042523.1 442899 D 282459 CDS YP_042524.1 49485303 2863763 complement(444508..444816) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0437; hypothetical protein 444816 2863763 SAS0398 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042524.1 444508 R 282459 CDS YP_042525.1 49485304 2862306 445152..445964 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0440; lipoprotein 445964 2862306 SAS0399 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_042525.1 445152 D 282459 CDS YP_042526.1 49485305 2863927 446012..446782 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0442; hypothetical protein 446782 2863927 SAS0400 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042526.1 446012 D 282459 CDS YP_042527.1 49485306 2863928 446814..447605 1 NC_002953.3 lipoprotein 447605 2863928 SAS0401 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_042527.1 446814 D 282459 CDS YP_042528.1 49485307 2862170 447657..448454 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0444; lipoprotein 448454 2862170 SAS0402 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_042528.1 447657 D 282459 CDS YP_042529.1 49485308 2862171 448633..449448 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0443; lipoprotein 449448 2862171 SAS0403 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_042529.1 448633 D 282459 CDS YP_042530.1 49485309 2862208 449438..450763 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0446; hypothetical protein 450763 2862208 SAS0404 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042530.1 449438 D 282459 CDS YP_042531.1 49485310 2863942 450760..451083 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0447; hypothetical protein 451083 2863942 SAS0405 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042531.1 450760 D 282459 CDS YP_042532.1 49485311 2863943 451102..451416 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0448; hypothetical protein 451416 2863943 SAS0406 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042532.1 451102 D 282459 CDS YP_042533.1 49485312 2862172 complement(451700..451894) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0449; hypothetical protein 451894 2862172 SAS0407 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042533.1 451700 R 282459 CDS YP_042534.1 49485313 2862164 452092..453294 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0450; cobalamin synthesis protein 453294 2862164 SAS0408 Staphylococcus aureus subsp. aureus MSSA476 cobalamin synthesis protein YP_042534.1 452092 D 282459 CDS YP_042535.1 49485314 2862165 453563..453691 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0451; hypothetical protein 453691 2862165 SAS0409 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042535.1 453563 D 282459 CDS YP_042536.1 49485315 2863127 454880..456364 1 NC_002953.3 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit 5 456364 2863127 SAS0410 Staphylococcus aureus subsp. aureus MSSA476 NADH dehydrogenase subunit 5 YP_042536.1 454880 D 282459 CDS YP_042537.1 49485316 2861856 456377..459082 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0453; hypothetical protein 459082 2861856 SAS0411 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042537.1 456377 D 282459 CDS YP_042538.1 49485317 2862081 459244..459606 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0454; hypothetical protein 459606 2862081 SAS0412 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042538.1 459244 D 282459 CDS YP_042539.1 49485318 2863184 complement(459835..460182) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0455; hypothetical protein 460182 2863184 SAS0413 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042539.1 459835 R 282459 CDS YP_042540.1 49485319 2863185 460289..460963 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0456; hypothetical protein 460963 2863185 SAS0414 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042540.1 460289 D 282459 CDS YP_042541.1 49485320 2862059 461000..461734 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0457; hypothetical protein 461734 2862059 SAS0415 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042541.1 461000 D 282459 CDS YP_042542.1 49485321 2861858 461912..462025 1 NC_002953.3 Doubtful CDS. No database matches; hypothetical protein 462025 2861858 SAS0415a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042542.1 461912 D 282459 CDS YP_042543.1 49485322 2863780 462187..463527 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0458; sodium:neurotransmitter symporter family protein 463527 2863780 SAS0416 Staphylococcus aureus subsp. aureus MSSA476 sodium:neurotransmitter symporter family protein YP_042543.1 462187 D 282459 CDS YP_042544.1 49485323 2863868 463744..464649 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0459; pyridoxal-phosphate dependent protein 464649 2863868 SAS0417 Staphylococcus aureus subsp. aureus MSSA476 pyridoxal-phosphate dependent protein YP_042544.1 463744 D 282459 CDS YP_042545.1 49485324 2863869 464642..465784 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0460; Cys/Met metabolism PLP-dependent enzyme 465784 2863869 SAS0418 Staphylococcus aureus subsp. aureus MSSA476 Cys/Met metabolism PLP-dependent enzyme YP_042545.1 464642 D 282459 CDS YP_042546.1 49485325 2863831 466081..467106 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0461; ABC transporter ATP-binding protein 467106 2863831 SAS0419 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042546.1 466081 D 282459 CDS YP_042547.1 49485326 2862433 467110..467769 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0462; transport system membrane protein 467769 2862433 SAS0420 Staphylococcus aureus subsp. aureus MSSA476 transport system membrane protein YP_042547.1 467110 D 282459 CDS YP_042548.1 49485327 2862434 467806..468648 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0463; lipoprotein 468648 2862434 SAS0421 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_042548.1 467806 D 282459 CDS YP_042549.1 49485328 2862318 468980..469984 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0464; hypothetical protein 469984 2862318 SAS0422 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042549.1 468980 D 282459 CDS YP_042550.1 49485329 2863840 complement(470169..470438) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0465; hypothetical protein 470438 2863840 SAS0423 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042550.1 470169 R 282459 CDS YP_042551.1 49485330 2863841 470578..470982 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0466; MutT domain-containing protein 470982 2863841 SAS0424 Staphylococcus aureus subsp. aureus MSSA476 MutT domain-containing protein YP_042551.1 470578 D 282459 CDS YP_042552.1 49485331 2862474 470972..471457 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0467; acetyltransferase 471457 2862474 SAS0425 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase YP_042552.1 470972 D 282459 CDS YP_042553.1 49485332 2862475 complement(471626..472408) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0468; hypothetical protein 472408 2862475 SAS0426 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042553.1 471626 R 282459 CDS YP_042554.1 49485333 2861861 complement(472405..473523) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0469; hypothetical protein 473523 2861861 SAS0427 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042554.1 472405 R 282459 CDS YP_042555.1 49485334 2862425 complement(473638..474522) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0470; LysR family regulatory protein 474522 2862425 SAS0428 Staphylococcus aureus subsp. aureus MSSA476 LysR family regulatory protein YP_042555.1 473638 R 282459 CDS YP_042556.1 49485335 2862426 474704..479203 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0471; glutamate synthase 479203 2862426 SAS0429 Staphylococcus aureus subsp. aureus MSSA476 glutamate synthase YP_042556.1 474704 D 282459 CDS YP_042557.1 49485336 2863858 479221..480684 1 NC_002953.3 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase 480684 gltD 2863858 gltD Staphylococcus aureus subsp. aureus MSSA476 glutamate synthase YP_042557.1 479221 D 282459 CDS YP_042558.1 49485337 2862448 481515..482942 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0473; sugar-specific PTS transport system, IIBC component 482942 2862448 SAS0431 Staphylococcus aureus subsp. aureus MSSA476 sugar-specific PTS transport system, IIBC component YP_042558.1 481515 D 282459 CDS YP_042559.1 49485338 2862449 483006..484646 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0474; glycosyl hydrolase 484646 2862449 SAS0432 Staphylococcus aureus subsp. aureus MSSA476 glycosyl hydrolase YP_042559.1 483006 D 282459 CDS YP_042560.1 49485339 2862493 484671..485399 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0475; GntR family transcriptional regulator 485399 2862493 SAS0433 Staphylococcus aureus subsp. aureus MSSA476 GntR family transcriptional regulator YP_042560.1 484671 D 282459 CDS YP_042562.1 49485341 2862896 486042..486566 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0476; acetyltransferase (GNAT) family protein 486566 2862896 SAS0434 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase (GNAT) family protein YP_042562.1 486042 D 282459 CDS YP_042563.1 49485342 2862932 486635..488332 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0477; DNA polymerase III, tau subunit 488332 2862932 SAS0435 Staphylococcus aureus subsp. aureus MSSA476 DNA polymerase III, tau subunit YP_042563.1 486635 D 282459 CDS YP_042564.1 49485343 2862933 488422..488739 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0478; hypothetical protein 488739 2862933 SAS0436 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042564.1 488422 D 282459 CDS YP_042565.1 49485344 2862918 488746..489342 1 NC_002953.3 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 489342 recR 2862918 recR Staphylococcus aureus subsp. aureus MSSA476 recombination protein RecR YP_042565.1 488746 D 282459 CDS YP_042566.1 49485345 2863530 496066..497403 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0482; Orn/Lys/Arg decarboxylase family protein 497403 2863530 SAS0438 Staphylococcus aureus subsp. aureus MSSA476 Orn/Lys/Arg decarboxylase family protein YP_042566.1 496066 D 282459 CDS YP_042567.1 49485346 2863531 497405..498022 1 NC_002953.3 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 498022 tmk 2863531 tmk Staphylococcus aureus subsp. aureus MSSA476 thymidylate kinase YP_042567.1 497405 D 282459 CDS YP_042568.1 49485347 2862992 498050..498379 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0484; hypothetical protein 498379 2862992 SAS0440 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042568.1 498050 D 282459 CDS YP_042569.1 49485348 2862993 498593..499519 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0485; DNA polymerase III subunit delta' 499519 2862993 SAS0441 Staphylococcus aureus subsp. aureus MSSA476 DNA polymerase III subunit delta' YP_042569.1 498593 D 282459 CDS YP_042570.1 49485349 2863541 499520..500323 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0486; hypothetical protein 500323 2863541 SAS0442 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042570.1 499520 D 282459 CDS YP_042571.1 49485350 2862952 500340..500687 1 NC_002953.3 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 500687 2862952 SAS0443 Staphylococcus aureus subsp. aureus MSSA476 DNA replication intiation control protein YabA YP_042571.1 500340 D 282459 CDS YP_042572.1 49485351 2862953 500961..501686 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0488; hypothetical protein 501686 2862953 SAS0444 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042572.1 500961 D 282459 CDS YP_042573.1 49485352 2861748 501679..501927 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0489; hypothetical protein 501927 2861748 SAS0445 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042573.1 501679 D 282459 CDS YP_042574.1 49485353 2862880 501929..502768 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0490; tetrapyrrole (corrin/porphyrin) methylase family protein 502768 2862880 SAS0446 Staphylococcus aureus subsp. aureus MSSA476 tetrapyrrole (corrin/porphyrin) methylase family protein YP_042574.1 501929 D 282459 CDS YP_042575.1 49485354 2862881 503053..505026 1 NC_002953.3 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 505026 2862881 SAS0447 Staphylococcus aureus subsp. aureus MSSA476 methionyl-tRNA synthetase YP_042575.1 503053 D 282459 CDS YP_042576.1 49485355 2861776 505057..505830 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0492; TatD related DNase 505830 2861776 SAS0448 Staphylococcus aureus subsp. aureus MSSA476 TatD related DNase YP_042576.1 505057 D 282459 CDS YP_042577.1 49485356 2861777 505997..506533 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0493; hypothetical protein 506533 2861777 SAS0449 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042577.1 505997 D 282459 CDS YP_042578.1 49485357 2864045 506544..507437 1 NC_002953.3 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 507437 ksgA 2864045 ksgA Staphylococcus aureus subsp. aureus MSSA476 dimethyladenosine transferase YP_042578.1 506544 D 282459 CDS YP_042579.1 49485358 2861826 507537..507800 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0495; hypothetical protein 507800 2861826 SAS0451 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042579.1 507537 D 282459 CDS YP_042580.1 49485359 2861827 508110..508958 1 NC_002953.3 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 508958 ipk 2861827 ipk Staphylococcus aureus subsp. aureus MSSA476 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_042580.1 508110 D 282459 CDS YP_042581.1 49485360 2861770 508972..509796 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0497; pur operon repressor 509796 2861770 SAS0453 Staphylococcus aureus subsp. aureus MSSA476 pur operon repressor YP_042581.1 508972 D 282459 CDS YP_042582.1 49485361 2862689 509813..510193 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0498; regulatory protein 510193 2862689 SAS0454 Staphylococcus aureus subsp. aureus MSSA476 regulatory protein YP_042582.1 509813 D 282459 CDS YP_042583.1 49485362 2862690 510265..510567 1 NC_002953.3 stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus; regulatory protein SpoVG 510567 2862690 SAS0455 Staphylococcus aureus subsp. aureus MSSA476 regulatory protein SpoVG YP_042583.1 510265 D 282459 CDS YP_042584.1 49485363 2864381 510911..512263 1 NC_002953.3 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 512263 glmU 2864381 glmU Staphylococcus aureus subsp. aureus MSSA476 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_042584.1 510911 D 282459 CDS YP_042585.1 49485364 2864382 512410..513375 1 NC_002953.3 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 513375 2864382 SAS0457 Staphylococcus aureus subsp. aureus MSSA476 ribose-phosphate pyrophosphokinase YP_042585.1 512410 D 282459 CDS YP_042586.1 49485365 2864014 513525..514178 1 NC_002953.3 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 514178 2864014 SAS0458 Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L25 YP_042586.1 513525 D 282459 CDS YP_042587.1 49485366 2861821 514458..515030 1 NC_002953.3 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 515030 2861821 SAS0459 Staphylococcus aureus subsp. aureus MSSA476 peptidyl-tRNA hydrolase YP_042587.1 514458 D 282459 CDS YP_042588.1 49485367 2861822 515030..518536 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0504; transcription-repair coupling factor 518536 2861822 SAS0460 Staphylococcus aureus subsp. aureus MSSA476 transcription-repair coupling factor YP_042588.1 515030 D 282459 CDS YP_042589.1 49485368 2862930 518526..520052 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0505; polysaccharide biosynthesis protein 520052 2862930 SAS0461 Staphylococcus aureus subsp. aureus MSSA476 polysaccharide biosynthesis protein YP_042589.1 518526 D 282459 CDS YP_042590.1 49485369 2864008 520052..521245 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0506; tetrapyrrole (corrin/porphyrin) methylase 521245 2864008 SAS0462 Staphylococcus aureus subsp. aureus MSSA476 tetrapyrrole (corrin/porphyrin) methylase YP_042590.1 520052 D 282459 CDS YP_042591.1 49485370 2864009 521242..521505 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0507; S4 domain-containing protein 521505 2864009 SAS0463 Staphylococcus aureus subsp. aureus MSSA476 S4 domain-containing protein YP_042591.1 521242 D 282459 CDS YP_042592.1 49485371 2862659 521523..521915 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0508; cell division protein 521915 2862659 SAS0464 Staphylococcus aureus subsp. aureus MSSA476 cell division protein YP_042592.1 521523 D 282459 CDS YP_042593.1 49485372 2862660 522020..522421 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0509; hypothetical protein 522421 2862660 SAS0465 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042593.1 522020 D 282459 CDS YP_042594.1 49485373 2863457 522601..523896 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0510; hypothetical protein 523896 2863457 SAS0466 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042594.1 522601 D 282459 CDS YP_042595.1 49485374 2863282 523901..524440 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0511; hypoxanthine phosphoribosyltransferase 524440 2863282 SAS0467 Staphylococcus aureus subsp. aureus MSSA476 hypoxanthine phosphoribosyltransferase YP_042595.1 523901 D 282459 CDS YP_042596.1 49485375 2863283 524697..526790 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0512; cell division protein 526790 2863283 SAS0468 Staphylococcus aureus subsp. aureus MSSA476 cell division protein YP_042596.1 524697 D 282459 CDS YP_042597.1 49485376 2862678 527019..527900 1 NC_002953.3 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 527900 hslO 2862678 hslO Staphylococcus aureus subsp. aureus MSSA476 Hsp33-like chaperonin YP_042597.1 527019 D 282459 CDS YP_042598.1 49485377 2863348 528079..529011 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0514; O-acetylserine (thiol)-lyase 529011 2863348 SAS0470 Staphylococcus aureus subsp. aureus MSSA476 O-acetylserine (thiol)-lyase YP_042598.1 528079 D 282459 CDS YP_042599.1 49485378 2863349 529227..530030 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0515; dihydropteroate synthase 530030 2863349 SAS0471 Staphylococcus aureus subsp. aureus MSSA476 dihydropteroate synthase YP_042599.1 529227 D 282459 CDS YP_042600.1 49485379 2863654 530008..530373 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0516; dihydroneopterin aldolase 530373 2863654 SAS0472 Staphylococcus aureus subsp. aureus MSSA476 dihydroneopterin aldolase YP_042600.1 530008 D 282459 CDS YP_042601.1 49485380 2863655 530370..530846 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0517; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 530846 2863655 SAS0473 Staphylococcus aureus subsp. aureus MSSA476 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_042601.1 530370 D 282459 CDS YP_042602.1 49485381 2863056 531385..532872 1 NC_002953.3 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 532872 lysS 2863056 lysS Staphylococcus aureus subsp. aureus MSSA476 lysyl-tRNA synthetase YP_042602.1 531385 D 282459 CDS YP_042603.1 49485382 2863054 complement(545308..546690) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0521; GntR family transcriptional regulator 546690 2863054 SAS0475 Staphylococcus aureus subsp. aureus MSSA476 GntR family transcriptional regulator YP_042603.1 545308 R 282459 CDS YP_042604.1 49485383 2863055 546794..547681 1 NC_002953.3 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 547681 2863055 SAS0476 Staphylococcus aureus subsp. aureus MSSA476 pyridoxal biosynthesis lyase PdxS YP_042604.1 546794 D 282459 CDS YP_042605.1 49485384 2864102 547685..548245 1 NC_002953.3 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 548245 2864102 SAS0477 Staphylococcus aureus subsp. aureus MSSA476 glutamine amidotransferase subunit PdxT YP_042605.1 547685 D 282459 CDS YP_042606.1 49485385 2863659 complement(548451..549665) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0524; nucleoside permease 549665 2863659 SAS0478 Staphylococcus aureus subsp. aureus MSSA476 nucleoside permease YP_042606.1 548451 R 282459 CDS YP_042607.1 49485386 2863660 549823..550284 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0525; DNA-binding protein 550284 2863660 SAS0479 Staphylococcus aureus subsp. aureus MSSA476 DNA-binding protein YP_042607.1 549823 D 282459 CDS YP_042608.1 49485387 2862225 550303..550869 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0526; hypothetical protein 550869 2862225 SAS0480 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042608.1 550303 D 282459 CDS YP_042609.1 49485388 2862226 550859..551866 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0527; ATP:guanido phosphotransferase 551866 2862226 SAS0481 Staphylococcus aureus subsp. aureus MSSA476 ATP:guanido phosphotransferase YP_042609.1 550859 D 282459 CDS YP_042610.1 49485389 2864181 551880..554336 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0528; stress response-related Clp ATPase 554336 2864181 SAS0482 Staphylococcus aureus subsp. aureus MSSA476 stress response-related Clp ATPase YP_042610.1 551880 D 282459 CDS YP_042611.1 49485390 2864054 554820..556184 1 NC_002953.3 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 556184 2864054 SAS0483 Staphylococcus aureus subsp. aureus MSSA476 DNA repair protein RadA YP_042611.1 554820 D 282459 CDS YP_042612.1 49485391 2864055 556209..557282 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0530; hypothetical protein 557282 2864055 SAS0484 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042612.1 556209 D 282459 CDS YP_042613.1 49485392 2862586 557839..559293 1 NC_002953.3 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 559293 gltX 2862586 gltX Staphylococcus aureus subsp. aureus MSSA476 glutamyl-tRNA synthetase YP_042613.1 557839 D 282459 CDS YP_042614.1 49485393 2864217 559716..560363 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0532; serine acetyltransferase 560363 2864217 SAS0486 Staphylococcus aureus subsp. aureus MSSA476 serine acetyltransferase YP_042614.1 559716 D 282459 CDS YP_042615.1 49485394 2864129 560347..561747 1 NC_002953.3 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 561747 cysS 2864129 cysS Staphylococcus aureus subsp. aureus MSSA476 cysteinyl-tRNA synthetase YP_042615.1 560347 D 282459 CDS YP_042616.1 49485395 2864109 561740..562144 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0534; hypothetical protein 562144 2864109 SAS0488 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042616.1 561740 D 282459 CDS YP_042617.1 49485396 2864110 562152..562898 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0535; SpoU rRNA methylase family protein 562898 2864110 SAS0489 Staphylococcus aureus subsp. aureus MSSA476 SpoU rRNA methylase family protein YP_042617.1 562152 D 282459 CDS YP_042618.1 49485397 2862310 562898..563422 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0536; hypothetical protein 563422 2862310 SAS0490 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042618.1 562898 D 282459 CDS YP_042619.1 49485398 2862027 563503..564072 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0537; hypothetical protein 564072 2862027 SAS0491 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042619.1 563503 D 282459 CDS YP_042620.1 49485399 2862028 564187..564330 1 NC_002953.3 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 564330 rpmG 2862028 rpmG Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L33 YP_042620.1 564187 D 282459 CDS YP_042621.1 49485400 2862587 564386..564568 1 NC_002953.3 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 564568 secE 2862587 secE Staphylococcus aureus subsp. aureus MSSA476 preprotein translocase subunit SecE YP_042621.1 564386 D 282459 CDS YP_042622.1 49485401 2862715 564581..565129 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0540; transcription antitermination protein 565129 2862715 SAS0494 Staphylococcus aureus subsp. aureus MSSA476 transcription antitermination protein YP_042622.1 564581 D 282459 CDS YP_042623.1 49485402 2862716 565310..565732 1 NC_002953.3 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 565732 rplK 2862716 rplK Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L11 YP_042623.1 565310 D 282459 CDS YP_042624.1 49485403 2863958 565940..566632 1 NC_002953.3 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 566632 rplA 2863958 rplA Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L1 YP_042624.1 565940 D 282459 CDS YP_042625.1 49485404 2863959 566904..567404 1 NC_002953.3 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 567404 rplJ 2863959 rplJ Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L10 YP_042625.1 566904 D 282459 CDS YP_042626.1 49485405 2862363 567447..567815 1 NC_002953.3 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 567815 rplL 2862363 rplL Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L7/L12 YP_042626.1 567447 D 282459 CDS YP_042627.1 49485406 2862187 567990..568598 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0546; hypothetical protein 568598 2862187 SAS0499 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042627.1 567990 D 282459 CDS YP_042628.1 49485407 2862188 568813..572364 1 NC_002953.3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 572364 rpoB 2862188 rpoB Staphylococcus aureus subsp. aureus MSSA476 DNA-directed RNA polymerase subunit beta YP_042628.1 568813 D 282459 CDS YP_042629.1 49485408 2863814 572501..576124 1 NC_002953.3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 576124 2863814 SAS0501 Staphylococcus aureus subsp. aureus MSSA476 DNA-directed RNA polymerase subunit beta' YP_042629.1 572501 D 282459 CDS YP_042630.1 49485409 2863186 576204..576515 1 NC_002953.3 in Bacillus subtilis this non-essential protein associates with the ribosome; ribosomal protein L7Ae-like 576515 2863186 SAS0502 Staphylococcus aureus subsp. aureus MSSA476 ribosomal protein L7Ae-like YP_042630.1 576204 D 282459 CDS YP_042631.1 49485410 2863187 576613..577026 1 NC_002953.3 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 577026 rpsL 2863187 rpsL Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S12 YP_042631.1 576613 D 282459 CDS YP_042632.1 49485411 2863084 577092..577562 1 NC_002953.3 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 577562 2863084 SAS0504 Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S7 YP_042632.1 577092 D 282459 CDS YP_042633.1 49485412 2863085 577685..579766 1 NC_002953.3 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 579766 2863085 SAS0505 Staphylococcus aureus subsp. aureus MSSA476 elongation factor G YP_042633.1 577685 D 282459 CDS YP_042634.1 49485413 2862502 579983..581167 1 NC_002953.3 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 581167 tuf 2862502 tuf Staphylococcus aureus subsp. aureus MSSA476 elongation factor Tu YP_042634.1 579983 D 282459 CDS YP_042635.1 49485414 2861944 complement(581449..582624) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0554; peptidase 582624 2861944 SAS0507 Staphylococcus aureus subsp. aureus MSSA476 peptidase YP_042635.1 581449 R 282459 CDS YP_042636.1 49485415 2862781 582795..583982 1 NC_002953.3 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase 583982 2862781 SAS0508 Staphylococcus aureus subsp. aureus MSSA476 2-amino-3-ketobutyrate CoA ligase YP_042636.1 582795 D 282459 CDS YP_042637.1 49485416 2861897 584249..585127 1 NC_002953.3 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 585127 2861897 SAS0509 Staphylococcus aureus subsp. aureus MSSA476 chaperone protein HchA YP_042637.1 584249 D 282459 CDS YP_042638.1 49485417 2862218 585286..586923 1 NC_002953.3 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 586923 2862218 SAS0510 Staphylococcus aureus subsp. aureus MSSA476 ribulokinase YP_042638.1 585286 D 282459 CDS YP_042639.1 49485418 2862219 587137..588102 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0558; hypothetical protein 588102 2862219 SAS0511 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042639.1 587137 D 282459 CDS YP_042640.1 49485419 2862725 588437..589513 1 NC_002953.3 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 589513 2862725 SAS0512 Staphylococcus aureus subsp. aureus MSSA476 branched-chain amino acid aminotransferase YP_042640.1 588437 D 282459 CDS YP_042641.1 49485420 2862726 589764..590447 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0560; haloacid dehalogenase 590447 2862726 SAS0513 Staphylococcus aureus subsp. aureus MSSA476 haloacid dehalogenase YP_042641.1 589764 D 282459 CDS YP_042642.1 49485421 2863699 complement(590563..591225) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0561; deoxyadenosine kinase 591225 2863699 SAS0514 Staphylococcus aureus subsp. aureus MSSA476 deoxyadenosine kinase YP_042642.1 590563 R 282459 CDS YP_042643.1 49485422 2864336 complement(591218..591835) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0562; deoxyadenosine kinase 591835 2864336 SAS0515 Staphylococcus aureus subsp. aureus MSSA476 deoxyadenosine kinase YP_042643.1 591218 R 282459 CDS YP_042644.1 49485423 2864337 591902..592372 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0563; deaminase 592372 2864337 SAS0516 Staphylococcus aureus subsp. aureus MSSA476 deaminase YP_042644.1 591902 D 282459 CDS YP_042645.1 49485424 2861999 592519..593388 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0564; haloacid dehalogenase 593388 2861999 SAS0517 Staphylococcus aureus subsp. aureus MSSA476 haloacid dehalogenase YP_042645.1 592519 D 282459 CDS YP_042646.1 49485425 2862035 593409..593975 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0565; hypothetical protein 593975 2862035 SAS0518 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042646.1 593409 D 282459 CDS YP_042647.1 49485426 2862036 594406..597279 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0566; surface anchored protein 597279 2862036 SAS0519 Staphylococcus aureus subsp. aureus MSSA476 surface anchored protein YP_042647.1 594406 D 282459 CDS YP_042648.1 49485427 2863340 597646..601743 1 NC_002953.3 surface anchored protein 601743 2863340 SAS0520 Staphylococcus aureus subsp. aureus MSSA476 surface anchored protein YP_042648.1 597646 D 282459 CDS YP_042649.1 49485428 2863341 602137..605562 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0567; bone sialoprotein-binding protein 605562 2863341 SAS0521 Staphylococcus aureus subsp. aureus MSSA476 bone sialoprotein-binding protein YP_042649.1 602137 D 282459 CDS YP_042650.1 49485429 2863331 605681..607153 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0568; glycosyl transferase family protein 607153 2863331 SAS0522 Staphylococcus aureus subsp. aureus MSSA476 glycosyl transferase family protein YP_042650.1 605681 D 282459 CDS YP_042651.1 49485430 2863687 complement(607277..608767) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0569; glycosyl transferase family protein 608767 2863687 SAS0523 Staphylococcus aureus subsp. aureus MSSA476 glycosyl transferase family protein YP_042651.1 607277 R 282459 CDS YP_042652.1 49485431 2863688 complement(609049..609927) 1 NC_002953.3 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis; GTP cyclohydrolase 609927 2863688 SAS0524 Staphylococcus aureus subsp. aureus MSSA476 GTP cyclohydrolase YP_042652.1 609049 R 282459 CDS YP_042653.1 49485432 2861823 complement(609940..610605) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0571; hypothetical protein 610605 2861823 SAS0525 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042653.1 609940 R 282459 CDS YP_042654.1 49485433 2861815 complement(610619..610978) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0572; hypothetical protein 610978 2861815 SAS0526 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042654.1 610619 R 282459 CDS YP_042655.1 49485434 2861816 611257..612015 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0573; glucosamine-6-phosphate isomerase 612015 2861816 SAS0527 Staphylococcus aureus subsp. aureus MSSA476 glucosamine-6-phosphate isomerase YP_042655.1 611257 D 282459 CDS YP_042656.1 49485435 2863266 612092..612724 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0574; hexulose-6-phosphate synthase 612724 2863266 SAS0528 Staphylococcus aureus subsp. aureus MSSA476 hexulose-6-phosphate synthase YP_042656.1 612092 D 282459 CDS YP_042657.1 49485436 2863267 612726..613274 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0575; 6-phospho 3-hexuloisomerase 613274 2863267 SAS0529 Staphylococcus aureus subsp. aureus MSSA476 6-phospho 3-hexuloisomerase YP_042657.1 612726 D 282459 CDS YP_042658.1 49485437 2864461 613387..614034 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0576; haloacid dehalogenase 614034 2864461 SAS0530 Staphylococcus aureus subsp. aureus MSSA476 haloacid dehalogenase YP_042658.1 613387 D 282459 CDS YP_042659.1 49485438 2863164 614536..615936 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0577; proline/betaine transporter 615936 2863164 SAS0531 Staphylococcus aureus subsp. aureus MSSA476 proline/betaine transporter YP_042659.1 614536 D 282459 CDS YP_042660.1 49485439 2863165 616187..616480 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0578; hypothetical protein 616480 2863165 SAS0532 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042660.1 616187 D 282459 CDS YP_042661.1 49485440 2862066 616480..617856 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0580; AMP-binding protein 617856 2862066 SAS0533 Staphylococcus aureus subsp. aureus MSSA476 AMP-binding protein YP_042661.1 616480 D 282459 CDS YP_042662.1 49485441 2862419 617858..618997 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0581; ketoacyl-CoA thiolase 618997 2862419 SAS0534 Staphylococcus aureus subsp. aureus MSSA476 ketoacyl-CoA thiolase YP_042662.1 617858 D 282459 CDS YP_042663.1 49485442 2862420 618972..619337 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0582; hypothetical protein 619337 2862420 SAS0535 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042663.1 618972 D 282459 CDS YP_042664.1 49485443 2862203 619340..619609 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0583; hypothetical protein 619609 2862203 SAS0536 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042664.1 619340 D 282459 CDS YP_042665.1 49485444 2862204 complement(619810..619977) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0584; hypothetical protein 619977 2862204 SAS0537 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042665.1 619810 R 282459 CDS YP_042666.1 49485445 2862138 complement(620484..621314) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0585; phosphomethylpyrimidine kinase 621314 2862138 SAS0538 Staphylococcus aureus subsp. aureus MSSA476 phosphomethylpyrimidine kinase YP_042666.1 620484 R 282459 CDS YP_042667.1 49485446 2864227 621498..622154 1 NC_002953.3 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 622154 2864227 SAS0539 Staphylococcus aureus subsp. aureus MSSA476 uracil-DNA glycosylase YP_042667.1 621498 D 282459 CDS YP_042668.1 49485447 2864228 622155..622535 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0587; hypothetical protein 622535 2864228 SAS0540 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042668.1 622155 D 282459 CDS YP_042669.1 49485448 2862399 622668..623036 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0588; hypothetical protein 623036 2862399 SAS0541 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042669.1 622668 D 282459 CDS YP_042670.1 49485449 2864267 623157..624641 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0589; amino acid permease 624641 2864267 SAS0542 Staphylococcus aureus subsp. aureus MSSA476 amino acid permease YP_042670.1 623157 D 282459 CDS YP_042671.1 49485450 2864268 complement(624782..625234) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0590; hypothetical protein 625234 2864268 SAS0543 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042671.1 624782 R 282459 CDS YP_042672.1 49485451 2862160 complement(625247..626011) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0591; hypothetical protein 626011 2862160 SAS0544 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042672.1 625247 R 282459 CDS YP_042673.1 49485452 2862161 626322..626519 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0592; hypothetical protein 626519 2862161 SAS0545 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042673.1 626322 D 282459 CDS YP_042674.1 49485453 2862129 complement(626560..627312) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0593; heme peroxidase 627312 2862129 SAS0546 Staphylococcus aureus subsp. aureus MSSA476 heme peroxidase YP_042674.1 626560 R 282459 CDS YP_042675.1 49485454 2862069 627480..628466 1 NC_002953.3 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 628466 eutD 2862069 eutD Staphylococcus aureus subsp. aureus MSSA476 phosphotransacetylase YP_042675.1 627480 D 282459 CDS YP_042676.1 49485455 2862070 628469..629305 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0595; lipoate-protein ligase A 629305 2862070 SAS0548 Staphylococcus aureus subsp. aureus MSSA476 lipoate-protein ligase A YP_042676.1 628469 D 282459 CDS YP_042677.1 49485456 2862207 629892..630812 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0596; mevalonate kinase 630812 2862207 SAS0549 Staphylococcus aureus subsp. aureus MSSA476 mevalonate kinase YP_042677.1 629892 D 282459 CDS YP_042678.1 49485457 2862077 630817..631800 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0597; mevalonate diphosphate decarboxylase 631800 2862077 SAS0550 Staphylococcus aureus subsp. aureus MSSA476 mevalonate diphosphate decarboxylase YP_042678.1 630817 D 282459 CDS YP_042679.1 49485458 2862078 631813..632889 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0598; phosphomevalonate kinase 632889 2862078 SAS0551 Staphylococcus aureus subsp. aureus MSSA476 phosphomevalonate kinase YP_042679.1 631813 D 282459 CDS YP_042680.1 49485459 2863823 633066..633407 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0599; hypothetical protein 633407 2863823 SAS0552 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042680.1 633066 D 282459 CDS YP_042681.1 49485460 2863824 complement(633459..634781) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0600; pyridine nucleotide-disulfide oxidoreductase 634781 2863824 SAS0553 Staphylococcus aureus subsp. aureus MSSA476 pyridine nucleotide-disulfide oxidoreductase YP_042681.1 633459 R 282459 CDS YP_042682.1 49485461 2862450 complement(634768..635208) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0601; hypothetical protein 635208 2862450 SAS0554 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042682.1 634768 R 282459 CDS YP_042683.1 49485462 2863111 635833..637242 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0602; hypothetical protein 637242 2863111 SAS0555 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042683.1 635833 D 282459 CDS YP_042684.1 49485463 2863112 637246..637872 1 NC_002953.3 Similar to Staphylococcus haemolyticus hypothetical protein SWALL:Q9F2H5 (EMBL:AJ302698) (220 aa) fasta scores: E(): 6.1e-07, 23.28% id in 189 aa, and to Oceanobacillus iheyensis hypothetical conserved protein ob3290 SWALL:Q8ELD9 (EMBL:AP004604) (212 aa) fasta scores: E(): 3.6e-06, 21.56% id in 218 aa; hypothetical protein 637872 2863112 SAS0556 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042684.1 637246 D 282459 CDS YP_042685.1 49485464 2862458 638008..638640 1 NC_002953.3 Similar to Oceanobacillus iheyensis hypothetical conserved protein ob1330 SWALL:Q8ERH2 (EMBL:AP004597) (217 aa) fasta scores: E(): 2.9e-07, 26.6% id in 218 aa, and to Staphylococcus haemolyticus hypothetical protein SWALL:Q9F2H5 (EMBL:AJ302698) (220 aa) fasta scores: E(): 5.3e-07, 27.55% id in 196 aa; hypothetical protein 638640 2862458 SAS0557 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042685.1 638008 D 282459 CDS YP_042686.1 49485465 2863168 638728..639345 1 NC_002953.3 Similar to Oceanobacillus iheyensis hypothetical conserved protein ob1336 SWALL:Q8ERG6 (EMBL:AP004597) (219 aa) fasta scores: E(): 2.3e-06, 25.58% id in 215 aa, and to Staphylococcus haemolyticus hypothetical protein SWALL:Q9F2H5 (EMBL:AJ302698) (220 aa) fasta scores: E(): 1.3e-05, 21.1% id in 199 aa; hypothetical protein 639345 2863168 SAS0558 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042686.1 638728 D 282459 CDS YP_042687.1 49485466 2863169 639420..640049 1 NC_002953.3 Similar to Oceanobacillus iheyensis hypothetical conserved protein ob1320 SWALL:Q8ERI2 (EMBL:AP004597) (215 aa) fasta scores: E(): 5.8e-07, 24.17% id in 211 aa, and to Staphylococcus haemolyticus hypothetical protein SWALL:Q9F2H5 (EMBL:AJ302698) (220 aa) fasta scores: E(): 2e-07, 22.48% id in 209 aa; hypothetical protein 640049 2863169 SAS0559 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042687.1 639420 D 282459 CDS YP_042688.1 49485467 2863860 640997..641638 1 NC_002953.3 Similar to Staphylococcus haemolyticus hypothetical protein SWALL:Q9F2H5 (EMBL:AJ302698) (220 aa) fasta scores: E(): 3.4e-07, 22.91% id in 192 aa, and to Oceanobacillus iheyensis hypothetical conserved protein ob3291 SWALL:Q8ELD8 (EMBL:AP004604) (216 aa) fasta scores: E(): 9.7e-07, 24.51% id in 208 aa; hypothetical protein 641638 2863860 SAS0562 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042688.1 640997 D 282459 CDS YP_042689.1 49485468 2863584 641685..642314 1 NC_002953.3 Similar to Oceanobacillus iheyensis hypothetical conserved protein ob1336 SWALL:Q8ERG6 (EMBL:AP004597) (219 aa) fasta scores: E(): 8.9e-09, 24.88% id in 221 aa, and to Staphylococcus haemolyticus hypothetical protein SWALL:Q9F2H5 (EMBL:AJ302698) (220 aa) fasta scores: E(): 1.1e-07, 25.26% id in 186 aa; hypothetical protein 642314 2863584 SAS0563 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042689.1 641685 D 282459 CDS YP_042690.1 49485469 2863578 642767..643396 1 NC_002953.3 Similar to Staphylococcus haemolyticus hypothetical protein SWALL:Q9F2H5 (EMBL:AJ302698) (220 aa) fasta scores: E(): 8.2e-10, 27.6% id in 192 aa, and to Oceanobacillus iheyensis hypothetical conserved protein ob3290 SWALL:Q8ELD9 (EMBL:AP004604) (212 aa) fasta scores: E(): 1.1e-09, 26.31% id in 209 aa; hypothetical protein 643396 2863578 SAS0564 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042690.1 642767 D 282459 CDS YP_042691.1 49485470 2863579 643511..644161 1 NC_002953.3 Similar to Oceanobacillus iheyensis hypothetical conserved protein ob1330 SWALL:Q8ERH2 (EMBL:AP004597) (217 aa) fasta scores: E(): 1.2e-09, 29.24% id in 212 aa, and to Staphylococcus haemolyticus hypothetical protein SWALL:Q9F2H5 (EMBL:AJ302698) (220 aa) fasta scores: E(): 2.2e-07, 27.04% id in 196 aa; hypothetical protein 644161 2863579 SAS0565 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042691.1 643511 D 282459 CDS YP_042692.1 49485471 2863018 644198..644833 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0603; hypothetical protein 644833 2863018 SAS0566 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042692.1 644198 D 282459 CDS YP_042693.1 49485472 2862926 645068..645694 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0605; hypothetical protein 645694 2862926 SAS0567 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042693.1 645068 D 282459 CDS YP_042694.1 49485473 2862927 645964..646902 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0608; aldo/keto reductase 646902 2862927 SAS0568 Staphylococcus aureus subsp. aureus MSSA476 aldo/keto reductase YP_042694.1 645964 D 282459 CDS YP_042695.1 49485474 2863014 647113..647649 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0609; hypothetical protein 647649 2863014 SAS0569 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042695.1 647113 D 282459 CDS YP_042696.1 49485475 2863015 647818..648294 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0610; acetyltransferase 648294 2863015 SAS0570 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase YP_042696.1 647818 D 282459 CDS YP_042697.1 49485476 2864038 648334..649629 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0611; phosphohydrolase 649629 2864038 SAS0571 Staphylococcus aureus subsp. aureus MSSA476 phosphohydrolase YP_042697.1 648334 D 282459 CDS YP_042698.1 49485477 2863521 649672..650178 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0612; hypothetical protein 650178 2863521 SAS0572 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042698.1 649672 D 282459 CDS YP_042699.1 49485478 2863522 650677..651687 1 NC_002953.3 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 651687 2863522 SAS0573 Staphylococcus aureus subsp. aureus MSSA476 alcohol dehydrogenase YP_042699.1 650677 D 282459 CDS YP_042700.1 49485479 2861750 651764..651871 1 NC_002953.3 Doubtful CDS. No database matches; hypothetical protein 651871 2861750 SAS0573a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042700.1 651764 D 282459 CDS YP_042701.1 49485480 2861760 651952..652380 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0614; hypothetical protein 652380 2861760 SAS0574 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042701.1 651952 D 282459 CDS YP_042702.1 49485481 2861761 652377..654038 1 NC_002953.3 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 654038 argS 2861761 argS Staphylococcus aureus subsp. aureus MSSA476 arginyl-tRNA synthetase YP_042702.1 652377 D 282459 CDS YP_042703.1 49485482 2861751 654429..655064 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0617; DNA repair protein 655064 2861751 SAS0576 Staphylococcus aureus subsp. aureus MSSA476 DNA repair protein YP_042703.1 654429 D 282459 CDS YP_042704.1 49485483 2861752 655315..656202 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0618; transport system lipoprotein 656202 2861752 SAS0577 Staphylococcus aureus subsp. aureus MSSA476 transport system lipoprotein YP_042704.1 655315 D 282459 CDS YP_042705.1 49485484 2861809 656351..657301 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0619; FecCD transport family protein 657301 2861809 SAS0578 Staphylococcus aureus subsp. aureus MSSA476 FecCD transport family protein YP_042705.1 656351 D 282459 CDS YP_042706.1 49485485 2861789 657356..658075 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0620; haloacid dehalogenase 658075 2861789 SAS0579 Staphylococcus aureus subsp. aureus MSSA476 haloacid dehalogenase YP_042706.1 657356 D 282459 CDS YP_042707.1 49485486 2861790 658059..658859 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0621; hydrolase 658859 2861790 SAS0580 Staphylococcus aureus subsp. aureus MSSA476 hydrolase YP_042707.1 658059 D 282459 CDS YP_042708.1 49485487 2862755 658995..659501 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0622; hypothetical protein 659501 2862755 SAS0581 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042708.1 658995 D 282459 CDS YP_042709.1 49485488 2863264 659663..660379 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0623; hypothetical protein 660379 2863264 SAS0582 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042709.1 659663 D 282459 CDS YP_042710.1 49485489 2863265 660548..661336 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0624; esterase 661336 2863265 SAS0583 Staphylococcus aureus subsp. aureus MSSA476 esterase YP_042710.1 660548 D 282459 CDS YP_042711.1 49485490 2863304 complement(661586..661960) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0625; accessory regulator A 661960 2863304 SAS0584 Staphylococcus aureus subsp. aureus MSSA476 accessory regulator A YP_042711.1 661586 R 282459 CDS YP_042712.1 49485491 2863305 complement(662908..663837) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0626; hypothetical protein 663837 2863305 SAS0585 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042712.1 662908 R 282459 CDS YP_042713.1 49485492 2862661 complement(664032..664256) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0627; hypothetical protein 664256 2862661 SAS0586 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042713.1 664032 R 282459 CDS YP_042714.1 49485493 2863656 complement(664273..664476) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0628; hypothetical protein 664476 2863656 SAS0587 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042714.1 664273 R 282459 CDS YP_042715.1 49485494 2863657 664635..665195 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0629; phage integrase family protein 665195 2863657 SAS0588 Staphylococcus aureus subsp. aureus MSSA476 phage integrase family protein YP_042715.1 664635 D 282459 CDS YP_042716.1 49485495 2863466 665214..667616 1 NC_002953.3 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit A 667616 2863466 SAS0589 Staphylococcus aureus subsp. aureus MSSA476 monovalent cation/H+ antiporter subunit A YP_042716.1 665214 D 282459 CDS YP_042717.1 49485496 2863049 667603..668028 1 NC_002953.3 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit B 668028 2863049 SAS0590 Staphylococcus aureus subsp. aureus MSSA476 monovalent cation/H+ antiporter subunit B YP_042717.1 667603 D 282459 CDS YP_042718.1 49485497 2863050 668025..668369 1 NC_002953.3 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit C 668369 2863050 SAS0591 Staphylococcus aureus subsp. aureus MSSA476 monovalent cation/H+ antiporter subunit C YP_042718.1 668025 D 282459 CDS YP_042719.1 49485498 2863432 668359..669855 1 NC_002953.3 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; in S. meliloti it is known to be involved specifically with K+ transport; monovalent cation/H+ antiporter subunit D 669855 2863432 SAS0592 Staphylococcus aureus subsp. aureus MSSA476 monovalent cation/H+ antiporter subunit D YP_042719.1 668359 D 282459 CDS YP_042720.1 49485499 2863433 669856..670338 1 NC_002953.3 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; monovalent cation/H+ antiporter subunit E 670338 2863433 SAS0593 Staphylococcus aureus subsp. aureus MSSA476 monovalent cation/H+ antiporter subunit E YP_042720.1 669856 D 282459 CDS YP_042721.1 49485500 2863644 670335..670637 1 NC_002953.3 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit F 670637 2863644 SAS0594 Staphylococcus aureus subsp. aureus MSSA476 monovalent cation/H+ antiporter subunit F YP_042721.1 670335 D 282459 CDS YP_042722.1 49485501 2863033 670612..671049 1 NC_002953.3 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit G 671049 2863033 SAS0595 Staphylococcus aureus subsp. aureus MSSA476 monovalent cation/H+ antiporter subunit G YP_042722.1 670612 D 282459 CDS YP_042723.1 49485502 2863034 671389..673431 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0637; sodium/hydrogen exchanger family protein 673431 2863034 SAS0596 Staphylococcus aureus subsp. aureus MSSA476 sodium/hydrogen exchanger family protein YP_042723.1 671389 D 282459 CDS YP_042724.1 49485503 2863063 complement(674592..675521) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0641; ABC transporter extracellular binding protein 675521 2863063 SAS0597 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter extracellular binding protein YP_042724.1 674592 R 282459 CDS YP_042725.1 49485504 2864283 complement(675518..676354) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0642; ABC transporter permease 676354 2864283 SAS0598 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter permease YP_042725.1 675518 R 282459 CDS YP_042726.1 49485505 2864284 complement(676348..677091) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0643; ABC transporter ATP-binding protein 677091 2864284 SAS0599 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042726.1 676348 R 282459 CDS YP_042727.1 49485506 2862236 677213..677857 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0644; metalloregulator 677857 2862236 SAS0600 Staphylococcus aureus subsp. aureus MSSA476 metalloregulator YP_042727.1 677213 D 282459 CDS YP_042728.1 49485507 2862237 complement(677937..678689) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0645; hypothetical protein 678689 2862237 SAS0601 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042728.1 677937 R 282459 CDS YP_042729.1 49485508 2864117 678925..679689 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0646; teichoic acid biosynthesis protein 679689 2864117 SAS0602 Staphylococcus aureus subsp. aureus MSSA476 teichoic acid biosynthesis protein YP_042729.1 678925 D 282459 CDS YP_042730.1 49485509 2864114 complement(679750..680544) 1 NC_002953.3 with TagG is involved in the export of teichoic acids; teichoic acids export protein ATP-binding subunit 680544 2864114 SAS0603 Staphylococcus aureus subsp. aureus MSSA476 teichoic acids export protein ATP-binding subunit YP_042730.1 679750 R 282459 CDS YP_042731.1 49485510 2864115 680870..681703 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0648; teichoic acid ABC transporter permease 681703 2864115 SAS0604 Staphylococcus aureus subsp. aureus MSSA476 teichoic acid ABC transporter permease YP_042731.1 680870 D 282459 CDS YP_042732.1 49485511 2864139 681802..682905 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0649; teichoic acid biosynthesis protein 682905 2864139 SAS0605 Staphylococcus aureus subsp. aureus MSSA476 teichoic acid biosynthesis protein YP_042732.1 681802 D 282459 CDS YP_042733.1 49485512 2864174 682902..683963 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0650; glycosyl transferase family protein 683963 2864174 SAS0606 Staphylococcus aureus subsp. aureus MSSA476 glycosyl transferase family protein YP_042733.1 682902 D 282459 CDS YP_042734.1 49485513 2864175 684026..684424 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0651; glycerol-3-phosphate cytidylyltransferase 684424 2864175 SAS0607 Staphylococcus aureus subsp. aureus MSSA476 glycerol-3-phosphate cytidylyltransferase YP_042734.1 684026 D 282459 CDS YP_042735.1 49485514 2864211 complement(684541..685836) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0652; penicillin-binding protein 4 685836 2864211 SAS0608 Staphylococcus aureus subsp. aureus MSSA476 penicillin-binding protein 4 YP_042735.1 684541 R 282459 CDS YP_042736.1 49485515 2864212 686257..687984 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0653; ABC transporter ATP-binding protein 687984 2864212 SAS0609 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042736.1 686257 D 282459 CDS YP_042738.1 49485517 2864184 688341..689570 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0655; Na+ dependent nucleoside transporter 689570 2864184 SAS0610 Staphylococcus aureus subsp. aureus MSSA476 Na+ dependent nucleoside transporter YP_042738.1 688341 D 282459 CDS YP_042739.1 49485518 2862577 690095..690928 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0656; hypothetical protein 690928 2862577 SAS0611 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042739.1 690095 D 282459 CDS YP_042740.1 49485519 2861995 691210..692007 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0657; ferrichrome ABC transporter ATP-binding protein 692007 2861995 SAS0612 Staphylococcus aureus subsp. aureus MSSA476 ferrichrome ABC transporter ATP-binding protein YP_042740.1 691210 D 282459 CDS YP_042741.1 49485520 2862173 692043..693047 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0658; ferrichrome transport permease 693047 2862173 SAS0613 Staphylococcus aureus subsp. aureus MSSA476 ferrichrome transport permease YP_042741.1 692043 D 282459 CDS YP_042742.1 49485521 2862174 693044..694060 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0659; ferrichrome transport permease 694060 2862174 SAS0614 Staphylococcus aureus subsp. aureus MSSA476 ferrichrome transport permease YP_042742.1 693044 D 282459 CDS YP_042743.1 49485522 2862004 694294..695262 1 NC_002953.3 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; dihydroxyacetone kinase subunit DhaK 695262 2862004 SAS0615 Staphylococcus aureus subsp. aureus MSSA476 dihydroxyacetone kinase subunit DhaK YP_042743.1 694294 D 282459 CDS YP_042744.1 49485523 2862005 695304..695888 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0661; dihydroxyacetone kinase 695888 2862005 SAS0616 Staphylococcus aureus subsp. aureus MSSA476 dihydroxyacetone kinase YP_042744.1 695304 D 282459 CDS YP_042745.1 49485524 2863697 695881..696243 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0662; PTS system mannnose-specific transporter subunit IIA 696243 2863697 SAS0617 Staphylococcus aureus subsp. aureus MSSA476 PTS system mannnose-specific transporter subunit IIA YP_042745.1 695881 D 282459 CDS YP_042746.1 49485525 2862037 696359..696856 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0663; hypothetical protein 696856 2862037 SAS0618 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042746.1 696359 D 282459 CDS YP_042747.1 49485526 2863333 697313..698380 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0664; hypothetical protein 698380 2863333 SAS0619 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042747.1 697313 D 282459 CDS YP_042748.1 49485527 2863701 698531..699574 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0665; esterase 699574 2863701 SAS0620 Staphylococcus aureus subsp. aureus MSSA476 esterase YP_042748.1 698531 D 282459 CDS YP_042749.1 49485528 2862402 699903..700331 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0666; hypothetical protein 700331 2862402 SAS0621 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042749.1 699903 D 282459 CDS YP_042750.1 49485529 2862403 complement(700540..701046) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0667; hypothetical protein 701046 2862403 SAS0622 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042750.1 700540 R 282459 CDS YP_042751.1 49485530 2863970 701159..702082 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0668; hypothetical protein 702082 2863970 SAS0623 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042751.1 701159 D 282459 CDS YP_042752.1 49485531 2863971 702098..702772 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0669; response regulator protein 702772 2863971 SAS0624 Staphylococcus aureus subsp. aureus MSSA476 response regulator protein YP_042752.1 702098 D 282459 CDS YP_042753.1 49485532 2862189 702765..703805 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0670; sensor histidine kinase 703805 2862189 SAS0625 Staphylococcus aureus subsp. aureus MSSA476 sensor histidine kinase YP_042753.1 702765 D 282459 CDS YP_042754.1 49485533 2863960 703949..704710 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0671; ABC transporter 704710 2863960 SAS0626 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter YP_042754.1 703949 D 282459 CDS YP_042755.1 49485534 2863961 704700..706589 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0672; ABC transporter permease 706589 2863961 SAS0627 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter permease YP_042755.1 704700 D 282459 CDS YP_042756.1 49485535 2863386 707314..707931 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0673; hypothetical protein 707931 2863386 SAS0628 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042756.1 707314 D 282459 CDS YP_042757.1 49485536 2862736 707947..708954 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0674; phosphate transport protein 708954 2862736 SAS0629 Staphylococcus aureus subsp. aureus MSSA476 phosphate transport protein YP_042757.1 707947 D 282459 CDS YP_042758.1 49485537 2862737 complement(709542..710339) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0675; hypothetical protein 710339 2862737 SAS0630 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042758.1 709542 R 282459 CDS YP_042759.1 49485538 2861921 710700..711344 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0676; hypothetical protein 711344 2861921 SAS0631 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042759.1 710700 D 282459 CDS YP_042760.1 49485539 2861922 712041..714191 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0677; AraC family transcriptional regulator 714191 2861922 SAS0632 Staphylococcus aureus subsp. aureus MSSA476 AraC family transcriptional regulator YP_042760.1 712041 D 282459 CDS YP_042761.1 49485540 2863643 714271..714696 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0679; hypothetical protein 714696 2863643 SAS0633 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042761.1 714271 D 282459 CDS YP_042762.1 49485541 2862105 714886..715602 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0680; hypothetical protein 715602 2862105 SAS0634 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042762.1 714886 D 282459 CDS YP_042763.1 49485542 2862106 715602..716075 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0681; hypothetical protein 716075 2862106 SAS0635 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042763.1 715602 D 282459 CDS YP_042764.1 49485543 2863798 716428..717072 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0682; hypothetical protein 717072 2863798 SAS0636 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042764.1 716428 D 282459 CDS YP_042765.1 49485544 2862574 717188..718054 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0683; LysR family regulatory protein 718054 2862574 SAS0637 Staphylococcus aureus subsp. aureus MSSA476 LysR family regulatory protein YP_042765.1 717188 D 282459 CDS YP_042766.1 49485545 2862575 718393..719613 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0684; sugar efflux transporter 719613 2862575 SAS0638 Staphylococcus aureus subsp. aureus MSSA476 sugar efflux transporter YP_042766.1 718393 D 282459 CDS YP_042767.1 49485546 2862117 719610..720098 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0685; hypothetical protein 720098 2862117 SAS0639 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042767.1 719610 D 282459 CDS YP_042768.1 49485547 2862118 complement(720197..720886) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0728; hypothetical protein 720886 2862118 SAS0640 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042768.1 720197 R 282459 CDS YP_042769.1 49485548 2863325 721013..721456 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0729; acetyltransferase 721456 2863325 SAS0641 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase YP_042769.1 721013 D 282459 CDS YP_042770.1 49485549 2863159 721523..721918 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0730; hypothetical protein 721918 2863159 SAS0642 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042770.1 721523 D 282459 CDS YP_042771.1 49485550 2863160 722056..722355 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0731; hypothetical protein 722355 2863160 SAS0643 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042771.1 722056 D 282459 CDS YP_042772.1 49485551 2863941 722435..722977 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0732; acetyltransferase 722977 2863941 SAS0644 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase YP_042772.1 722435 D 282459 CDS YP_042773.1 49485552 2863842 complement(723073..723639) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0733; hypothetical protein 723639 2863842 SAS0645 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042773.1 723073 R 282459 CDS YP_042774.1 49485553 2863843 complement(723641..724099) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0734; hypothetical protein 724099 2863843 SAS0646 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042774.1 723641 R 282459 CDS YP_042775.1 49485554 2863719 complement(724102..724785) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0735; hypothetical protein 724785 2863719 SAS0647 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042775.1 724102 R 282459 CDS YP_042776.1 49485555 2863720 complement(724957..725832) 1 NC_002953.3 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 725832 uppP 2863720 uppP Staphylococcus aureus subsp. aureus MSSA476 undecaprenyl pyrophosphate phosphatase YP_042776.1 724957 R 282459 CDS YP_042777.1 49485556 2862388 726051..727682 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0737; ABC transporter ATP-binding protein 727682 2862388 SAS0649 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042777.1 726051 D 282459 CDS YP_042778.1 49485557 2861833 727679..729352 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0738; ABC transporter ATP-binding protein 729352 2861833 SAS0650 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042778.1 727679 D 282459 CDS YP_042779.1 49485558 2861834 complement(729479..729922) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0739; MarR family transcriptional regulator 729922 2861834 SAS0651 Staphylococcus aureus subsp. aureus MSSA476 MarR family transcriptional regulator YP_042779.1 729479 R 282459 CDS YP_042780.1 49485559 2864271 730149..731075 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0740; cobalamin synthesis protein 731075 2864271 SAS0652 Staphylococcus aureus subsp. aureus MSSA476 cobalamin synthesis protein YP_042780.1 730149 D 282459 CDS YP_042781.1 49485560 2863915 731178..732086 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0741; aldo/keto reductase 732086 2863915 SAS0653 Staphylococcus aureus subsp. aureus MSSA476 aldo/keto reductase YP_042781.1 731178 D 282459 CDS YP_042782.1 49485561 2863916 732121..732408 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0742; hypothetical protein 732408 2863916 SAS0654 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042782.1 732121 D 282459 CDS YP_042783.1 49485562 2863917 732691..734244 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0743; sodium:sulfate symporter protein 734244 2863917 SAS0655 Staphylococcus aureus subsp. aureus MSSA476 sodium:sulfate symporter protein YP_042783.1 732691 D 282459 CDS YP_042784.1 49485563 2863918 734330..735703 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0744; DNA photolyase 735703 2863918 SAS0656 Staphylococcus aureus subsp. aureus MSSA476 DNA photolyase YP_042784.1 734330 D 282459 CDS YP_042785.1 49485564 2862135 complement(735858..736142) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0745; hypothetical protein 736142 2862135 SAS0657 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042785.1 735858 R 282459 CDS YP_042786.1 49485565 2863113 complement(736139..736759) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0746; hypothetical protein 736759 2863113 SAS0658 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042786.1 736139 R 282459 CDS YP_042787.1 49485566 2863114 complement(736942..737364) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0747; hypothetical protein 737364 2863114 SAS0659 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042787.1 736942 R 282459 CDS YP_042788.1 49485567 2862199 737573..738739 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0748; fluoroquinolone resistance protein 738739 2862199 SAS0660 Staphylococcus aureus subsp. aureus MSSA476 fluoroquinolone resistance protein YP_042788.1 737573 D 282459 CDS YP_042789.1 49485568 2862042 739020..739484 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0749; hypothetical protein 739484 2862042 SAS0661 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042789.1 739020 D 282459 CDS YP_042790.1 49485569 2862043 739657..740139 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0750; hypothetical protein 740139 2862043 SAS0662 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042790.1 739657 D 282459 CDS YP_042791.1 49485570 2863863 740392..741153 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0751; DeoR ramily regulatory protein 741153 2863863 SAS0663 Staphylococcus aureus subsp. aureus MSSA476 DeoR ramily regulatory protein YP_042791.1 740392 D 282459 CDS YP_042792.1 49485571 2863864 741150..742070 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0752; phosphofructokinase 742070 2863864 SAS0664 Staphylococcus aureus subsp. aureus MSSA476 phosphofructokinase YP_042792.1 741150 D 282459 CDS YP_042793.1 49485572 2862064 742076..744034 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0753; PTS transport system, fructose-specific IIABC component 744034 2862064 SAS0665 Staphylococcus aureus subsp. aureus MSSA476 PTS transport system, fructose-specific IIABC component YP_042793.1 742076 D 282459 CDS YP_042794.1 49485573 2862841 744342..745523 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0754; N-acetylglucosamine-6-phosphate deacetylase 745523 2862841 SAS0666 Staphylococcus aureus subsp. aureus MSSA476 N-acetylglucosamine-6-phosphate deacetylase YP_042794.1 744342 D 282459 CDS YP_042795.1 49485574 2862842 745744..747093 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0755; hypothetical protein 747093 2862842 SAS0667 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042795.1 745744 D 282459 CDS YP_042796.1 49485575 2862418 747315..748154 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0756; aldo/keto reductase 748154 2862418 SAS0668 Staphylococcus aureus subsp. aureus MSSA476 aldo/keto reductase YP_042796.1 747315 D 282459 CDS YP_042797.1 49485576 2863825 748286..749269 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0757; glucosyl transferase 749269 2863825 SAS0669 Staphylococcus aureus subsp. aureus MSSA476 glucosyl transferase YP_042797.1 748286 D 282459 CDS YP_042798.1 49485577 2863826 complement(749341..750396) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0758; histidine kinase 750396 2863826 SAS0670 Staphylococcus aureus subsp. aureus MSSA476 histidine kinase YP_042798.1 749341 R 282459 CDS YP_042799.1 49485578 2862467 complement(750396..751082) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0759; response regulator protein 751082 2862467 SAS0671 Staphylococcus aureus subsp. aureus MSSA476 response regulator protein YP_042799.1 750396 R 282459 CDS YP_042800.1 49485579 2862468 complement(751057..751530) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0760; hypothetical protein 751530 2862468 SAS0672 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042800.1 751057 R 282459 CDS YP_042801.1 49485580 2862428 complement(751873..752313) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0761; hypothetical protein 752313 2862428 SAS0673 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042801.1 751873 R 282459 CDS YP_042802.1 49485581 2863865 complement(752593..753177) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0762; hypothetical protein 753177 2863865 SAS0674 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042802.1 752593 R 282459 CDS YP_042803.1 49485582 2863866 complement(753276..753989) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0763; radical activating enzyme 753989 2863866 SAS0675 Staphylococcus aureus subsp. aureus MSSA476 radical activating enzyme YP_042803.1 753276 R 282459 CDS YP_042804.1 49485583 2862476 complement(753993..754412) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0764; 6-pyruvoyl tetrahydrobiopterin synthase 754412 2862476 SAS0676 Staphylococcus aureus subsp. aureus MSSA476 6-pyruvoyl tetrahydrobiopterin synthase YP_042804.1 753993 R 282459 CDS YP_042805.1 49485584 2862469 complement(754414..755082) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0765; hypothetical protein 755082 2862469 SAS0677 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042805.1 754414 R 282459 CDS YP_042806.1 49485585 2862470 755433..756026 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0766; glutamine amidotransferase class-I protein 756026 2862470 SAS0678 Staphylococcus aureus subsp. aureus MSSA476 glutamine amidotransferase class-I protein YP_042806.1 755433 D 282459 CDS YP_042807.1 49485586 2862483 756010..757161 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0767; para-aminobenzoate synthase component 757161 2862483 SAS0679 Staphylococcus aureus subsp. aureus MSSA476 para-aminobenzoate synthase component YP_042807.1 756010 D 282459 CDS YP_042808.1 49485587 2862484 757161..757769 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0768; para-aminobenzoate synthetase component 757769 2862484 SAS0680 Staphylococcus aureus subsp. aureus MSSA476 para-aminobenzoate synthetase component YP_042808.1 757161 D 282459 CDS YP_042809.1 49485588 2863852 757835..758041 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0769; hypothetical protein 758041 2863852 SAS0681 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042809.1 757835 D 282459 CDS YP_042810.1 49485589 2863242 758129..758839 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0770; hypothetical protein 758839 2863242 SAS0682 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042810.1 758129 D 282459 CDS YP_042811.1 49485590 2863243 758823..759827 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0771; hypothetical protein 759827 2863243 SAS0683 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042811.1 758823 D 282459 CDS YP_042812.1 49485591 2863857 760301..762241 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0772; sulfatase 762241 2863857 SAS0684 Staphylococcus aureus subsp. aureus MSSA476 sulfatase YP_042812.1 760301 D 282459 CDS YP_042813.1 49485592 2863554 762518..764395 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0773; ABC transporter ATP-binding protein 764395 2863554 SAS0685 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042813.1 762518 D 282459 CDS YP_042814.1 49485593 2863555 764407..766188 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0774; ATP-dependent DNA helicase 766188 2863555 SAS0686 Staphylococcus aureus subsp. aureus MSSA476 ATP-dependent DNA helicase YP_042814.1 764407 D 282459 CDS YP_042815.1 49485594 2863536 766410..767387 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0775; ABC transporter ATP-binding protein 767387 2863536 SAS0687 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042815.1 766410 D 282459 CDS YP_042816.1 49485595 2863537 767380..768894 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0776; ABC transporter permease 768894 2863537 SAS0688 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter permease YP_042816.1 767380 D 282459 CDS YP_042817.1 49485596 2861762 769134..770192 1 NC_002953.3 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 770192 2861762 SAS0689 Staphylococcus aureus subsp. aureus MSSA476 histidinol-phosphate aminotransferase YP_042817.1 769134 D 282459 CDS YP_042818.1 49485597 2863565 770487..771029 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0778; hypothetical protein 771029 2863565 SAS0690 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042818.1 770487 D 282459 CDS YP_042819.1 49485598 2863566 complement(771710..772627) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0780; diacylglycerol kinase 772627 2863566 SAS0691 Staphylococcus aureus subsp. aureus MSSA476 diacylglycerol kinase YP_042819.1 771710 R 282459 CDS YP_042820.1 49485599 2864387 complement(772896..774401) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0781; proton-dependent oligopeptide transport protein 774401 2864387 SAS0692 Staphylococcus aureus subsp. aureus MSSA476 proton-dependent oligopeptide transport protein YP_042820.1 772896 R 282459 CDS YP_042821.1 49485600 2861793 complement(774742..775242) 1 NC_002953.3 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 775242 2861793 SAS0693 Staphylococcus aureus subsp. aureus MSSA476 7-cyano-7-deazaguanine reductase YP_042821.1 774742 R 282459 CDS YP_042822.1 49485601 2861794 complement(775262..776128) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0783; hypothetical protein 776128 2861794 SAS0694 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042822.1 775262 R 282459 CDS YP_042823.1 49485602 2864419 776929..777327 1 NC_002953.3 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 777327 nrdI 2864419 nrdI Staphylococcus aureus subsp. aureus MSSA476 ribonucleotide reductase stimulatory protein YP_042823.1 776929 D 282459 CDS YP_042824.1 49485603 2864420 777290..779395 1 NC_002953.3 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 779395 2864420 SAS0696 Staphylococcus aureus subsp. aureus MSSA476 ribonucleotide-diphosphate reductase subunit alpha YP_042824.1 777290 D 282459 CDS YP_042825.1 49485604 2861804 779513..780484 1 NC_002953.3 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 780484 nrdF 2861804 nrdF Staphylococcus aureus subsp. aureus MSSA476 ribonucleotide-diphosphate reductase subunit beta YP_042825.1 779513 D 282459 CDS YP_042826.1 49485605 2862760 781192..782163 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0787; FecCD transport family protein 782163 2862760 SAS0698 Staphylococcus aureus subsp. aureus MSSA476 FecCD transport family protein YP_042826.1 781192 D 282459 CDS YP_042827.1 49485606 2862761 782150..783106 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0788; FecCD transport family protein 783106 2862761 SAS0699 Staphylococcus aureus subsp. aureus MSSA476 FecCD transport family protein YP_042827.1 782150 D 282459 CDS YP_042828.1 49485607 2861818 783103..783864 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0789; ABC transporter ATP-binding protein 783864 2861818 SAS0700 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042828.1 783103 D 282459 CDS YP_042829.1 49485608 2864446 783983..785011 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0790; lipoprotein 785011 2864446 SAS0701 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_042829.1 783983 D 282459 CDS YP_042830.1 49485609 2864447 complement(785328..785642) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0791; hypothetical protein 785642 2864447 SAS0702 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042830.1 785328 R 282459 CDS YP_042831.1 49485610 2863468 complement(785660..786583) 1 NC_002953.3 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 786583 murB 2863468 murB Staphylococcus aureus subsp. aureus MSSA476 UDP-N-acetylenolpyruvoylglucosamine reductase YP_042831.1 785660 R 282459 CDS YP_042832.1 49485611 2863469 complement(786710..787228) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0793; hypothetical protein 787228 2863469 SAS0704 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042832.1 786710 R 282459 CDS YP_042833.1 49485612 2863297 787348..788226 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0794; hypothetical protein 788226 2863297 SAS0705 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042833.1 787348 D 282459 CDS YP_042834.1 49485613 2863274 788380..788700 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0795; hypothetical protein 788700 2863274 SAS0706 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042834.1 788380 D 282459 CDS YP_042835.1 49485614 2863275 789125..790249 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0796; glycerate kinase 790249 2863275 SAS0707 Staphylococcus aureus subsp. aureus MSSA476 glycerate kinase YP_042835.1 789125 D 282459 CDS YP_042836.1 49485615 2863335 complement(790431..791657) 1 NC_002953.3 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 791657 2863335 SAS0708 Staphylococcus aureus subsp. aureus MSSA476 peptidase T YP_042836.1 790431 R 282459 CDS YP_042837.1 49485616 2863299 complement(791671..792165) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0798; hypothetical protein 792165 2863299 SAS0709 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042837.1 791671 R 282459 CDS YP_042838.1 49485617 2863300 complement(792183..792944) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0799; hypothetical protein 792944 2863300 SAS0710 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042838.1 792183 R 282459 CDS YP_042839.1 49485618 2863650 complement(793140..794210) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0800; hypothetical protein 794210 2863650 SAS0711 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042839.1 793140 R 282459 CDS YP_042840.1 49485619 2863651 794528..795583 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0801; glycosyl transferase 795583 2863651 SAS0712 Staphylococcus aureus subsp. aureus MSSA476 glycosyl transferase YP_042840.1 794528 D 282459 CDS YP_042841.1 49485620 2862664 complement(795755..796396) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0802; hypothetical protein 796396 2862664 SAS0713 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042841.1 795755 R 282459 CDS YP_042842.1 49485621 2863045 796540..797406 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0803; hypothetical protein 797406 2863045 SAS0714 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042842.1 796540 D 282459 CDS YP_042843.1 49485622 2863046 797770..798852 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0804; helicase 798852 2863046 SAS0715 Staphylococcus aureus subsp. aureus MSSA476 helicase YP_042843.1 797770 D 282459 CDS YP_042844.1 49485623 2862631 798845..799519 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0805; hypothetical protein 799519 2862631 SAS0716 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042844.1 798845 D 282459 CDS YP_042845.1 49485624 2864324 799580..800152 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0806; S30EA family ribosomal protein 800152 2864324 SAS0717 Staphylococcus aureus subsp. aureus MSSA476 S30EA family ribosomal protein YP_042845.1 799580 D 282459 CDS YP_042846.1 49485625 2864325 800566..803097 1 NC_002953.3 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 803097 secA 2864325 secA Staphylococcus aureus subsp. aureus MSSA476 preprotein translocase subunit SecA YP_042846.1 800566 D 282459 CDS YP_042847.1 49485626 2864294 join(803412..803483,803485..804522) 1 NC_002953.3 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 804522 prfB 2864294 prfB Staphylococcus aureus subsp. aureus MSSA476 peptide chain release factor 2 YP_042847.1 803412 D 282459 CDS YP_042848.1 49485627 2864295 804931..805770 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0809; hypothetical protein 805770 2864295 SAS0720 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042848.1 804931 D 282459 CDS YP_042849.1 49485628 2861873 805944..806594 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0810; phosphohydrolase 806594 2861873 SAS0721 Staphylococcus aureus subsp. aureus MSSA476 phosphohydrolase YP_042849.1 805944 D 282459 CDS YP_042850.1 49485629 2864122 806591..806827 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0811; hypothetical protein 806827 2864122 SAS0722 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042850.1 806591 D 282459 CDS YP_042851.1 49485630 2864123 807090..809081 1 NC_002953.3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 809081 2864123 SAS0723 Staphylococcus aureus subsp. aureus MSSA476 excinuclease ABC subunit B YP_042851.1 807090 D 282459 CDS YP_042852.1 49485631 2862255 809089..811935 1 NC_002953.3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 811935 uvrA 2862255 uvrA Staphylococcus aureus subsp. aureus MSSA476 excinuclease ABC subunit A YP_042852.1 809089 D 282459 CDS YP_042853.1 49485632 2864347 812542..813474 1 NC_002953.3 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 813474 2864347 SAS0725 Staphylococcus aureus subsp. aureus MSSA476 HPr kinase/phosphorylase YP_042853.1 812542 D 282459 CDS YP_042854.1 49485633 2864348 813480..814319 1 NC_002953.3 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 814319 2864348 SAS0726 Staphylococcus aureus subsp. aureus MSSA476 prolipoprotein diacylglyceryl transferase YP_042854.1 813480 D 282459 CDS YP_042855.1 49485634 2864169 814327..814812 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0816; acetyltransferase 814812 2864169 SAS0727 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase YP_042855.1 814327 D 282459 CDS YP_042856.1 49485635 2864170 814820..816259 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0817; hypothetical protein 816259 2864170 SAS0728 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042856.1 814820 D 282459 CDS YP_042857.1 49485636 2864282 816326..817261 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0818; thioredoxin reductase 817261 2864282 SAS0729 Staphylococcus aureus subsp. aureus MSSA476 thioredoxin reductase YP_042857.1 816326 D 282459 CDS YP_042858.1 49485637 2863088 818026..818937 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0820; hypothetical protein 818937 2863088 SAS0730 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042858.1 818026 D 282459 CDS YP_042859.1 49485638 2863089 818934..819929 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0821; hypothetical protein 819929 2863089 SAS0731 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042859.1 818934 D 282459 CDS YP_042860.1 49485639 2862315 820040..820984 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0822; hypothetical protein 820984 2862315 SAS0732 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042860.1 820040 D 282459 CDS YP_042861.1 49485640 2864201 821557..822144 1 NC_002953.3 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 822144 clpP 2864201 clpP Staphylococcus aureus subsp. aureus MSSA476 ATP-dependent Clp protease proteolytic subunit YP_042861.1 821557 D 282459 CDS YP_042862.1 49485641 2864202 complement(822387..823289) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0825; hypothetical protein 823289 2864202 SAS0734 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042862.1 822387 R 282459 CDS YP_042863.1 49485642 2864199 823992..824621 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0826; hypothetical protein 824621 2864199 SAS0736 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042863.1 823992 D 282459 CDS YP_042864.1 49485643 2864200 825318..826331 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0827; glycolytic operon regulator 826331 2864200 SAS0737 Staphylococcus aureus subsp. aureus MSSA476 glycolytic operon regulator YP_042864.1 825318 D 282459 CDS YP_042865.1 49485644 2862414 826384..827394 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0828; glyceraldehyde 3-phosphate dehydrogenase 1 827394 2862414 SAS0738 Staphylococcus aureus subsp. aureus MSSA476 glyceraldehyde 3-phosphate dehydrogenase 1 YP_042865.1 826384 D 282459 CDS YP_042866.1 49485645 2862029 827533..828723 1 NC_002953.3 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 828723 pgk 2862029 pgk Staphylococcus aureus subsp. aureus MSSA476 phosphoglycerate kinase YP_042866.1 827533 D 282459 CDS YP_042867.1 49485646 2862030 828845..829606 1 NC_002953.3 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 829606 tpiA 2862030 tpiA Staphylococcus aureus subsp. aureus MSSA476 triosephosphate isomerase YP_042867.1 828845 D 282459 CDS YP_042868.1 49485647 2862551 829609..831126 1 NC_002953.3 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 831126 2862551 SAS0741 Staphylococcus aureus subsp. aureus MSSA476 phosphoglyceromutase YP_042868.1 829609 D 282459 CDS YP_042869.1 49485648 2861962 831256..832560 1 NC_002953.3 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 832560 eno 2861962 eno Staphylococcus aureus subsp. aureus MSSA476 phosphopyruvate hydratase YP_042869.1 831256 D 282459 CDS YP_042870.1 49485649 2861963 832899..833357 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0833; hypothetical protein 833357 2861963 SAS0743 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042870.1 832899 D 282459 CDS YP_042871.1 49485650 2863707 833424..833657 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0834; preprotein translocase subunit SecG 833657 secG 2863707 secG Staphylococcus aureus subsp. aureus MSSA476 preprotein translocase subunit SecG YP_042871.1 833424 D 282459 CDS YP_042872.1 49485651 2863708 833773..834513 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0835; carboxylesterase 834513 2863708 SAS0745 Staphylococcus aureus subsp. aureus MSSA476 carboxylesterase YP_042872.1 833773 D 282459 CDS YP_042873.1 49485652 2863879 834547..836919 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0836; ribonuclease R 836919 2863879 SAS0746 Staphylococcus aureus subsp. aureus MSSA476 ribonuclease R YP_042873.1 834547 D 282459 CDS YP_042874.1 49485653 2863693 836941..837405 1 NC_002953.3 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 837405 smpB 2863693 smpB Staphylococcus aureus subsp. aureus MSSA476 SsrA-binding protein YP_042874.1 836941 D 282459 CDS YP_042875.1 49485654 2863694 complement(838270..838998) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0839; hypothetical protein 838998 2863694 SAS0749 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042875.1 838270 R 282459 CDS YP_042876.1 49485655 2862808 839596..840117 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0840; hypothetical protein 840117 2862808 SAS0750 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042876.1 839596 D 282459 CDS YP_042877.1 49485656 2863882 840256..840786 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0841; acetyltransferase 840786 2863882 SAS0751 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase YP_042877.1 840256 D 282459 CDS YP_042878.1 49485657 2863883 841049..843835 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0842; clumping factor 843835 2863883 SAS0752 Staphylococcus aureus subsp. aureus MSSA476 clumping factor YP_042878.1 841049 D 282459 CDS YP_042879.1 49485658 2862000 844056..845582 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0843; hypothetical protein 845582 2862000 SAS0753 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042879.1 844056 D 282459 CDS YP_042880.1 49485659 2862001 845933..846955 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0845; hypothetical protein 846955 2862001 SAS0754 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042880.1 845933 D 282459 CDS YP_042881.1 49485660 2863969 847290..847811 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0846; hypothetical protein 847811 2863969 SAS0755 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042881.1 847290 D 282459 CDS YP_042882.1 49485661 2862700 848152..848838 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0847; thermonuclease precursor 848838 2862700 SAS0756 Staphylococcus aureus subsp. aureus MSSA476 thermonuclease precursor YP_042882.1 848152 D 282459 CDS YP_042883.1 49485662 2862701 849195..849395 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0848; cold shock protein 849395 2862701 SAS0757 Staphylococcus aureus subsp. aureus MSSA476 cold shock protein YP_042883.1 849195 D 282459 CDS YP_042884.1 49485663 2862783 complement(849891..850109) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0849; hypothetical protein 850109 2862783 SAS0758 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042884.1 849891 R 282459 CDS YP_042885.1 49485664 2862786 complement(850171..850455) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0850; hypothetical protein 850455 2862786 SAS0759 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042885.1 850171 R 282459 CDS YP_042886.1 49485665 2862787 complement(850543..851112) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0851; hypothetical protein 851112 2862787 SAS0760 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042886.1 850543 R 282459 CDS YP_042887.1 49485666 2864220 complement(851300..851488) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0852; hypothetical protein 851488 2864220 SAS0761 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042887.1 851300 R 282459 CDS YP_042888.1 49485667 2864221 complement(851517..851777) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0853; hypothetical protein 851777 2864221 SAS0762 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042888.1 851517 R 282459 CDS YP_042889.1 49485668 2863560 852117..852320 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0854; hypothetical protein 852320 2863560 SAS0763 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042889.1 852117 D 282459 CDS YP_042890.1 49485669 2863419 complement(852317..852553) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0855; hypothetical protein 852553 2863419 SAS0764 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042890.1 852317 R 282459 CDS YP_042891.1 49485670 2863420 852777..853358 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0856; phosphoglycerate mutase family protein 853358 2863420 SAS0765 Staphylococcus aureus subsp. aureus MSSA476 phosphoglycerate mutase family protein YP_042891.1 852777 D 282459 CDS YP_042892.1 49485671 2864451 complement(853407..854024) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0857; LysE type translocator protein 854024 2864451 SAS0766 Staphylococcus aureus subsp. aureus MSSA476 LysE type translocator protein YP_042892.1 853407 R 282459 CDS YP_042893.1 49485672 2861864 complement(854179..854673) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0858; hypothetical protein 854673 2861864 SAS0767 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042893.1 854179 R 282459 CDS YP_042895.1 49485674 2862205 complement(855072..855494) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0859; OsmC-like protein 855494 2862205 SAS0768 Staphylococcus aureus subsp. aureus MSSA476 OsmC-like protein YP_042895.1 855072 R 282459 CDS YP_042896.1 49485675 2862206 855642..856358 1 NC_002953.3 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 856358 2862206 SAS0769 Staphylococcus aureus subsp. aureus MSSA476 3-dehydroquinate dehydratase YP_042896.1 855642 D 282459 CDS YP_042897.1 49485676 2863429 856441..856980 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0861; nitroreductase family protein 856980 2863429 SAS0770 Staphylococcus aureus subsp. aureus MSSA476 nitroreductase family protein YP_042897.1 856441 D 282459 CDS YP_042898.1 49485677 2862675 complement(857130..857450) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0862; thioredoxin 857450 2862675 SAS0771 Staphylococcus aureus subsp. aureus MSSA476 thioredoxin YP_042898.1 857130 R 282459 CDS YP_042899.1 49485678 2862676 857594..857950 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0863; hypothetical protein 857950 2862676 SAS0772 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042899.1 857594 D 282459 CDS YP_042900.1 49485679 2862749 858108..858488 1 NC_002953.3 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 858488 2862749 SAS0773 Staphylococcus aureus subsp. aureus MSSA476 glycine cleavage system protein H YP_042900.1 858108 D 282459 CDS YP_042901.1 49485680 2864440 858667..859545 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0865; hypothetical protein 859545 2864440 SAS0774 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042901.1 858667 D 282459 CDS YP_042902.1 49485681 2864441 complement(859569..859811) 1 NC_002953.3 Doubtful CDS. No significant database matches; hypothetical protein 859811 2864441 SAS0775 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042902.1 859569 R 282459 CDS YP_042903.1 49485682 2862507 860286..860672 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0867; hypothetical protein 860672 2862507 SAS0776 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042903.1 860286 D 282459 CDS YP_042904.1 49485683 2864372 860665..860961 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0868; hypothetical protein 860961 2864372 SAS0777 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042904.1 860665 D 282459 CDS YP_042905.1 49485684 2861829 861211..862236 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0870; ABC transporter ATP-binding protein 862236 2861829 SAS0779 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042905.1 861211 D 282459 CDS YP_042906.1 49485685 2863575 862229..862924 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0871; ABC transporter permease 862924 2863575 SAS0780 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter permease YP_042906.1 862229 D 282459 CDS YP_042907.1 49485686 2863576 862942..863763 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0872; lipoprotein 863763 2863576 SAS0781 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_042907.1 862942 D 282459 CDS YP_042908.1 49485687 2862850 864117..864311 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0874; hypothetical protein 864311 2862850 SAS0782 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042908.1 864117 D 282459 CDS YP_042909.1 49485688 2862912 complement(864544..865395) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0875; hypothetical protein 865395 2862912 SAS0783 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042909.1 864544 R 282459 CDS YP_042910.1 49485689 2862913 865723..866484 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0876; ABC transporter ATP-binding protein 866484 2862913 SAS0784 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_042910.1 865723 D 282459 CDS YP_042911.1 49485690 2862054 866582..867889 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0877; hypothetical protein 867889 2862054 SAS0785 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042911.1 866582 D 282459 CDS YP_042912.1 49485691 2862055 868004..869245 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0878; selenocysteine lyase 869245 2862055 SAS0786 Staphylococcus aureus subsp. aureus MSSA476 selenocysteine lyase YP_042912.1 868004 D 282459 CDS YP_042913.1 49485692 2862139 869235..869699 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0879; NifU-like protein 869699 2862139 SAS0787 Staphylococcus aureus subsp. aureus MSSA476 NifU-like protein YP_042913.1 869235 D 282459 CDS YP_042914.1 49485693 2863076 869850..871247 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0880; hypothetical protein 871247 2863076 SAS0788 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042914.1 869850 D 282459 CDS YP_042915.1 49485694 2863077 871434..871571 1 NC_002953.3 Doubtful CDS. No database matches; hypothetical protein 871571 2863077 SAS0788a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042915.1 871434 D 282459 CDS YP_042916.1 49485695 2863956 complement(871577..871891) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0881; hypothetical protein 871891 2863956 SAS0789 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042916.1 871577 R 282459 CDS YP_042917.1 49485696 2861842 872256..873296 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0882; hypothetical protein 873296 2861842 SAS0790 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042917.1 872256 D 282459 CDS YP_042918.1 49485697 2861843 873310..874377 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0883; dioxygenase 874377 2861843 SAS0791 Staphylococcus aureus subsp. aureus MSSA476 dioxygenase YP_042918.1 873310 D 282459 CDS YP_042919.1 49485698 2863945 874553..875401 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0884; hypothetical protein 875401 2863945 SAS0792 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042919.1 874553 D 282459 CDS YP_042920.1 49485699 2863946 875414..876241 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0885; hypothetical protein 876241 2863946 SAS0793 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042920.1 875414 D 282459 CDS YP_042921.1 49485700 2862053 876268..877587 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0886; 5'-nucleotidase 877587 2862053 SAS0794 Staphylococcus aureus subsp. aureus MSSA476 5'-nucleotidase YP_042921.1 876268 D 282459 CDS YP_042922.1 49485701 2862140 877671..878588 1 NC_002953.3 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 878588 2862140 SAS0795 Staphylococcus aureus subsp. aureus MSSA476 lipoyl synthase YP_042922.1 877671 D 282459 CDS YP_042923.1 49485702 2862141 878718..879101 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0888; hypothetical protein 879101 2862141 SAS0796 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042923.1 878718 D 282459 CDS YP_042924.1 49485703 2862824 complement(879180..879446) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0889; hypothetical protein 879446 2862824 SAS0797 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042924.1 879180 R 282459 CDS YP_042925.1 49485704 2863202 879544..879978 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0890; hypothetical protein 879978 2863202 SAS0798 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042925.1 879544 D 282459 CDS YP_042926.1 49485705 2863203 879978..880757 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0891; haloacid dehalogenase 880757 2863203 SAS0799 Staphylococcus aureus subsp. aureus MSSA476 haloacid dehalogenase YP_042926.1 879978 D 282459 CDS YP_042927.1 49485706 2862082 880790..881749 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0892; D-isomer specific 2-hydroxyacid dehydrogenase 881749 2862082 SAS0800 Staphylococcus aureus subsp. aureus MSSA476 D-isomer specific 2-hydroxyacid dehydrogenase YP_042927.1 880790 D 282459 CDS YP_042928.1 49485707 2862083 882161..882313 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0893; No significant database matches; hypothetical protein 882313 2862083 SAS0801 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042928.1 882161 D 282459 CDS YP_042929.1 49485708 2862202 882329..883786 1 NC_002953.3 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 883786 2862202 SAS0802 Staphylococcus aureus subsp. aureus MSSA476 D-alanine--poly(phosphoribitol) ligase subunit 1 YP_042929.1 882329 D 282459 CDS YP_042930.1 49485709 2863240 883783..884997 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0895; activated D-alanine transport protein 884997 2863240 SAS0803 Staphylococcus aureus subsp. aureus MSSA476 activated D-alanine transport protein YP_042930.1 883783 D 282459 CDS YP_042931.1 49485710 2863241 885015..885251 1 NC_002953.3 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 885251 2863241 SAS0804 Staphylococcus aureus subsp. aureus MSSA476 D-alanine--poly(phosphoribitol) ligase subunit 2 YP_042931.1 885015 D 282459 CDS YP_042932.1 49485711 2862489 885248..886423 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0897; lipoteichoic acid biosynthesis protein 886423 2862489 SAS0805 Staphylococcus aureus subsp. aureus MSSA476 lipoteichoic acid biosynthesis protein YP_042932.1 885248 D 282459 CDS YP_042933.1 49485712 2862490 complement(886686..886928) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0898; hypothetical protein 886928 2862490 SAS0806 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042933.1 886686 R 282459 CDS YP_042934.1 49485713 2862491 887029..887352 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0899; hypothetical protein 887352 2862491 SAS0807 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042934.1 887029 D 282459 CDS YP_042935.1 49485714 2862451 complement(887411..888475) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0900; pyridine nucleotide-disulfide oxidoreductase 888475 2862451 SAS0808 Staphylococcus aureus subsp. aureus MSSA476 pyridine nucleotide-disulfide oxidoreductase YP_042935.1 887411 R 282459 CDS YP_042936.1 49485715 2862452 888792..889028 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0901; hypothetical protein 889028 2862452 SAS0809 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042936.1 888792 D 282459 CDS YP_042937.1 49485716 2863542 889041..889400 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0902; hypothetical protein 889400 2863542 SAS0810 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042937.1 889041 D 282459 CDS YP_042938.1 49485717 2862916 889854..891062 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0903; pyridine nucleotide-disulfide oxidoreductase 891062 2862916 SAS0811 Staphylococcus aureus subsp. aureus MSSA476 pyridine nucleotide-disulfide oxidoreductase YP_042938.1 889854 D 282459 CDS YP_042939.1 49485718 2862917 891193..892668 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0904; cytosol aminopeptidase 892668 2862917 SAS0812 Staphylococcus aureus subsp. aureus MSSA476 cytosol aminopeptidase YP_042939.1 891193 D 282459 CDS YP_042940.1 49485719 2863558 893079..894395 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0905; transporter protein 894395 2863558 SAS0813 Staphylococcus aureus subsp. aureus MSSA476 transporter protein YP_042940.1 893079 D 282459 CDS YP_042941.1 49485720 2862950 894414..894788 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0906; hypothetical protein 894788 2862950 SAS0814 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042941.1 894414 D 282459 CDS YP_042942.1 49485721 2862951 complement(894844..895998) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0907; hypothetical protein 895998 2862951 SAS0815 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042942.1 894844 R 282459 CDS YP_042943.1 49485722 2863563 complement(896247..896603) 1 NC_002953.3 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit G 896603 2863563 SAS0816 Staphylococcus aureus subsp. aureus MSSA476 monovalent cation/H+ antiporter subunit G YP_042943.1 896247 R 282459 CDS YP_042944.1 49485723 2863564 complement(896581..896874) 1 NC_002953.3 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit F 896874 2863564 SAS0817 Staphylococcus aureus subsp. aureus MSSA476 monovalent cation/H+ antiporter subunit F YP_042944.1 896581 R 282459 CDS YP_042945.1 49485724 2861785 complement(896874..897353) 1 NC_002953.3 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit E 897353 2861785 SAS0818 Staphylococcus aureus subsp. aureus MSSA476 monovalent cation/H+ antiporter subunit E YP_042945.1 896874 R 282459 CDS YP_042946.1 49485725 2864021 complement(897355..898851) 1 NC_002953.3 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; monovalent cation/H+ antiporter subunit D 898851 2864021 SAS0819 Staphylococcus aureus subsp. aureus MSSA476 monovalent cation/H+ antiporter subunit D YP_042946.1 897355 R 282459 CDS YP_042947.1 49485726 2864022 complement(898844..899185) 1 NC_002953.3 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit C 899185 2864022 SAS0820 Staphylococcus aureus subsp. aureus MSSA476 monovalent cation/H+ antiporter subunit C YP_042947.1 898844 R 282459 CDS YP_042948.1 49485727 2863585 complement(899185..899613) 1 NC_002953.3 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in the case of S. meliloti it was proved to be involved specifically with K+ transport; monovalent cation/H+ antiporter subunit B 899613 2863585 SAS0821 Staphylococcus aureus subsp. aureus MSSA476 monovalent cation/H+ antiporter subunit B YP_042948.1 899185 R 282459 CDS YP_042949.1 49485728 2864030 complement(899606..902011) 1 NC_002953.3 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit A 902011 2864030 SAS0822 Staphylococcus aureus subsp. aureus MSSA476 monovalent cation/H+ antiporter subunit A YP_042949.1 899606 R 282459 CDS YP_042950.1 49485729 2864031 complement(902142..902525) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0915; hypothetical protein 902525 2864031 SAS0823 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042950.1 902142 R 282459 CDS YP_042951.1 49485730 2864379 902589..903182 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0916; cyclophilin type peptidyl-prolyl cis-trans isomerase 903182 2864379 SAS0824 Staphylococcus aureus subsp. aureus MSSA476 cyclophilin type peptidyl-prolyl cis-trans isomerase YP_042951.1 902589 D 282459 CDS YP_042952.1 49485731 2864380 903597..903974 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0917; S1 RNA-binding domain-containing protein 903974 2864380 SAS0825 Staphylococcus aureus subsp. aureus MSSA476 S1 RNA-binding domain-containing protein YP_042952.1 903597 D 282459 CDS YP_042953.1 49485732 2864400 904336..905463 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0918; NADH:flavin oxidoreductase / NADH oxidase family protein 905463 2864400 SAS0826 Staphylococcus aureus subsp. aureus MSSA476 NADH:flavin oxidoreductase / NADH oxidase family protein YP_042953.1 904336 D 282459 CDS YP_042954.1 49485733 2864407 905771..906961 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0919; ornithine--oxo-acid transaminase 906961 rocD 2864407 rocD Staphylococcus aureus subsp. aureus MSSA476 ornithine--oxo-acid transaminase YP_042954.1 905771 D 282459 CDS YP_042955.1 49485734 2864408 907070..908314 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0920; NAD-specific glutamate dehydrogenase 908314 2864408 SAS0828 Staphylococcus aureus subsp. aureus MSSA476 NAD-specific glutamate dehydrogenase YP_042955.1 907070 D 282459 CDS YP_042956.1 49485735 2864432 complement(908704..909633) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0921; glycerophosphoryl diester phosphodiesterase 909633 2864432 SAS0829 Staphylococcus aureus subsp. aureus MSSA476 glycerophosphoryl diester phosphodiesterase YP_042956.1 908704 R 282459 CDS YP_042957.1 49485736 2864019 complement(909875..911254) 1 NC_002953.3 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 911254 2864019 SAS0830 Staphylococcus aureus subsp. aureus MSSA476 argininosuccinate lyase YP_042957.1 909875 R 282459 CDS YP_042958.1 49485737 2864020 complement(911244..912449) 1 NC_002953.3 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 912449 2864020 SAS0831 Staphylococcus aureus subsp. aureus MSSA476 argininosuccinate synthase YP_042958.1 911244 R 282459 CDS YP_042959.1 49485738 2862773 912800..914131 1 NC_002953.3 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 914131 pgi 2862773 pgi Staphylococcus aureus subsp. aureus MSSA476 glucose-6-phosphate isomerase YP_042959.1 912800 D 282459 CDS YP_042960.1 49485739 2862774 914456..915031 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0925; hypothetical protein 915031 2862774 SAS0833 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042960.1 914456 D 282459 CDS YP_042961.1 49485740 2863293 915036..915560 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0926; signal peptidase Ia 915560 2863293 SAS0834 Staphylococcus aureus subsp. aureus MSSA476 signal peptidase Ia YP_042961.1 915036 D 282459 CDS YP_042962.1 49485741 2862780 915576..916151 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0927; signal peptidase Ib 916151 2862780 SAS0835 Staphylococcus aureus subsp. aureus MSSA476 signal peptidase Ib YP_042962.1 915576 D 282459 CDS YP_042963.1 49485742 2863515 916311..919787 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0928; hypothetical protein 919787 2863515 SAS0836 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042963.1 916311 D 282459 CDS YP_042964.1 49485743 2863347 919788..923441 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0929; hypothetical protein 923441 2863347 SAS0837 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042964.1 919788 D 282459 CDS YP_042965.1 49485744 2863367 923607..924509 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0930; fumarylacetoacetate (FAA) hydrolase family protein 924509 2863367 SAS0838 Staphylococcus aureus subsp. aureus MSSA476 fumarylacetoacetate (FAA) hydrolase family protein YP_042965.1 923607 D 282459 CDS YP_042966.1 49485745 2863368 924838..925227 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0931; hypothetical protein 925227 2863368 SAS0839 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042966.1 924838 D 282459 CDS YP_042967.1 49485746 2863373 complement(925399..926715) 1 NC_002953.3 NADPH-dependent; catalyzes the reduction of coenzyme A disulfide; coenzyme A disulfide reductase 926715 2863373 SAS0840 Staphylococcus aureus subsp. aureus MSSA476 coenzyme A disulfide reductase YP_042967.1 925399 R 282459 CDS YP_042968.1 49485747 2863374 complement(926767..927591) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0934; haloacid dehalogenase 927591 2863374 SAS0841 Staphylococcus aureus subsp. aureus MSSA476 haloacid dehalogenase YP_042968.1 926767 R 282459 CDS YP_042969.1 49485748 2863467 927705..928013 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0935; hypothetical protein 928013 2863467 SAS0842 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042969.1 927705 D 282459 CDS YP_042970.1 49485749 2862687 complement(928010..928102) 1 NC_002953.3 No database matches; hypothetical protein 928102 2862687 SAS0843 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042970.1 928010 R 282459 CDS YP_042971.1 49485750 2862038 928561..930375 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0937; hypothetical protein 930375 2862038 SAS0844 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042971.1 928561 D 282459 CDS YP_042972.1 49485751 2863437 930578..933187 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0938; ATPase of an ATP-dependent protease 933187 2863437 SAS0845 Staphylococcus aureus subsp. aureus MSSA476 ATPase of an ATP-dependent protease YP_042972.1 930578 D 282459 CDS YP_042973.1 49485752 2863029 complement(933246..934115) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0939; LysR family regulatory protein 934115 2863029 SAS0846 Staphylococcus aureus subsp. aureus MSSA476 LysR family regulatory protein YP_042973.1 933246 R 282459 CDS YP_042974.1 49485753 2863030 934225..935370 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0940; hypothetical protein 935370 2863030 SAS0847 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042974.1 934225 D 282459 CDS YP_042975.1 49485754 2863480 935354..935995 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0941; hypothetical protein 935995 2863480 SAS0848 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042975.1 935354 D 282459 CDS YP_042976.1 49485755 2863481 935988..937106 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0942; hypothetical protein 937106 2863481 SAS0849 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042976.1 935988 D 282459 CDS YP_042977.1 49485756 2863025 937090..937605 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0943; hypothetical protein 937605 2863025 SAS0850 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042977.1 937090 D 282459 CDS YP_042978.1 49485757 2863671 937916..938350 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0944; hypothetical protein 938350 2863671 SAS0851 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042978.1 937916 D 282459 CDS YP_042979.1 49485758 2863672 complement(938607..938792) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0945; hypothetical protein 938792 2863672 SAS0852 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042979.1 938607 R 282459 CDS YP_042980.1 49485759 2863616 939087..940028 1 NC_002953.3 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 940028 2863616 SAS0853 Staphylococcus aureus subsp. aureus MSSA476 3-oxoacyl-ACP synthase YP_042980.1 939087 D 282459 CDS YP_042981.1 49485760 2864316 940040..941284 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0947; 3-oxoacyl-ACP synthase 941284 2864316 SAS0854 Staphylococcus aureus subsp. aureus MSSA476 3-oxoacyl-ACP synthase YP_042981.1 940040 D 282459 CDS YP_042982.1 49485761 2864317 complement(941339..941710) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0948; hypothetical protein 941710 2864317 SAS0855 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042982.1 941339 R 282459 CDS YP_042983.1 49485762 2863047 941953..942879 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0949; oligopeptide transport system permease 942879 2863047 SAS0856 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transport system permease YP_042983.1 941953 D 282459 CDS YP_042984.1 49485763 2863048 942879..943949 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0950; oligopeptide transport system permease 943949 2863048 SAS0857 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transport system permease YP_042984.1 942879 D 282459 CDS YP_042985.1 49485764 2862256 943965..945047 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0951; oligopeptide transport ATP-binding protein 945047 2862256 SAS0858 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transport ATP-binding protein YP_042985.1 943965 D 282459 CDS YP_042986.1 49485765 2862317 945037..945978 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0952; oligopeptide transport ATP-binding protein 945978 2862317 SAS0859 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transport ATP-binding protein YP_042986.1 945037 D 282459 CDS YP_042987.1 49485766 2862322 945997..947652 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0953; transport system extracellular binding lipoprotein 947652 2862322 SAS0860 Staphylococcus aureus subsp. aureus MSSA476 transport system extracellular binding lipoprotein YP_042987.1 945997 D 282459 CDS YP_042988.1 49485767 2864290 947864..949579 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0954; transport system extracellular binding lipoprotein 949579 2864290 SAS0861 Staphylococcus aureus subsp. aureus MSSA476 transport system extracellular binding lipoprotein YP_042988.1 947864 D 282459 CDS YP_042989.1 49485768 2862562 949630..950616 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0957; oligopeptide transport ATP-binding protein 950616 2862562 SAS0862 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transport ATP-binding protein YP_042989.1 949630 D 282459 CDS YP_042990.1 49485769 2862563 950619..951599 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0958; oligopeptide transport ATP-binding protein 951599 2862563 SAS0863 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transport ATP-binding protein YP_042990.1 950619 D 282459 CDS YP_042991.1 49485770 2864142 951592..952554 1 NC_002953.3 oligopeptide transport system permease 952554 2864142 SAS0864 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transport system permease YP_042991.1 951592 D 282459 CDS YP_042992.1 49485771 2864143 952566..953447 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0960; oligopeptide transport system permease 953447 2864143 SAS0865 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transport system permease YP_042992.1 952566 D 282459 CDS YP_042993.1 49485772 2862592 complement(953489..954478) 1 NC_002953.3 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 954478 2862592 SAS0866 Staphylococcus aureus subsp. aureus MSSA476 tryptophanyl-tRNA synthetase YP_042993.1 953489 R 282459 CDS YP_042994.1 49485773 2864215 954773..955168 1 NC_002953.3 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 955168 spxA 2864215 spxA Staphylococcus aureus subsp. aureus MSSA476 transcriptional regulator Spx YP_042994.1 954773 D 282459 CDS YP_042995.1 49485774 2864216 955539..956258 1 NC_002953.3 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein 956258 2864216 SAS0868 Staphylococcus aureus subsp. aureus MSSA476 adaptor protein YP_042995.1 955539 D 282459 CDS YP_042996.1 49485775 2862593 956379..957365 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0967; hypothetical protein 957365 2862593 SAS0869 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042996.1 956379 D 282459 CDS YP_042997.1 49485776 2861972 957413..959221 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0968; oligopeptidase 959221 2861972 SAS0870 Staphylococcus aureus subsp. aureus MSSA476 oligopeptidase YP_042997.1 957413 D 282459 CDS YP_042998.1 49485777 2861973 complement(959681..960487) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0969; hypothetical protein 960487 2861973 SAS0871 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042998.1 959681 R 282459 CDS YP_042999.1 49485778 2861978 complement(960510..960875) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0970; hypothetical protein 960875 2861978 SAS0872 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_042999.1 960510 R 282459 CDS YP_043000.1 49485779 2861979 complement(960979..961572) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0971; hypothetical protein 961572 2861979 SAS0873 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043000.1 960979 R 282459 CDS YP_043001.1 49485780 2862006 961758..962105 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0972; hypothetical protein 962105 2862006 SAS0874 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043001.1 961758 D 282459 CDS YP_043002.1 49485781 2861976 962122..962757 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0973; GTP pyrophosphokinase 962757 2861976 SAS0875 Staphylococcus aureus subsp. aureus MSSA476 GTP pyrophosphokinase YP_043002.1 962122 D 282459 CDS YP_043003.1 49485782 2861977 962774..963583 1 NC_002953.3 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 963583 ppnK 2861977 ppnK Staphylococcus aureus subsp. aureus MSSA476 inorganic polyphosphate/ATP-NAD kinase YP_043003.1 962774 D 282459 CDS YP_043004.1 49485783 2861992 963580..964434 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0975; RNA pseudouridylate synthase 964434 2861992 SAS0877 Staphylococcus aureus subsp. aureus MSSA476 RNA pseudouridylate synthase YP_043004.1 963580 D 282459 CDS YP_043005.1 49485784 2862534 964455..965840 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0976; divalent cation transport protein 965840 2862534 SAS0878 Staphylococcus aureus subsp. aureus MSSA476 divalent cation transport protein YP_043005.1 964455 D 282459 CDS YP_043006.1 49485785 2862535 965850..967694 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0977; cation transport protein 967694 2862535 SAS0879 Staphylococcus aureus subsp. aureus MSSA476 cation transport protein YP_043006.1 965850 D 282459 CDS YP_043007.1 49485786 2862547 967972..968742 1 NC_002953.3 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-(acyl carrier protein) reductase 968742 2862547 SAS0880 Staphylococcus aureus subsp. aureus MSSA476 enoyl-(acyl carrier protein) reductase YP_043007.1 967972 D 282459 CDS YP_043008.1 49485787 2862548 complement(968937..970022) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0979; hypothetical protein 970022 2862548 SAS0881 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043008.1 968937 R 282459 CDS YP_043009.1 49485788 2863704 970364..971932 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0980; sodium:alanine symporter family protein 971932 2863704 SAS0882 Staphylococcus aureus subsp. aureus MSSA476 sodium:alanine symporter family protein YP_043009.1 970364 D 282459 CDS YP_043010.1 49485789 2862542 972077..972835 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0981; hypothetical protein 972835 2862542 SAS0883 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043010.1 972077 D 282459 CDS YP_043011.1 49485790 2862543 973029..973538 1 NC_002953.3 similar to 2'-5' RNA ligase; hypothetical protein 973538 2862543 SAS0884 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043011.1 973029 D 282459 CDS YP_043012.1 49485791 2861836 complement(973651..974841) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0986; hypothetical protein 974841 2861836 SAS0885 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043012.1 973651 R 282459 CDS YP_043013.1 49485792 2863511 complement(974819..975994) 1 NC_002953.3 processive; catalyzes the formation of mono-, di- and tri-glucosyldiacylglycerol by the progressive transfer of glucosyl residues to diacylglycerol; involved in the formation of membrane glycolipids; diacylglycerol glucosyltransferase 975994 2863511 SAS0886 Staphylococcus aureus subsp. aureus MSSA476 diacylglycerol glucosyltransferase YP_043013.1 974819 R 282459 CDS YP_043014.1 49485793 2863512 976427..977911 1 NC_002953.3 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase 977911 2863512 SAS0887 Staphylococcus aureus subsp. aureus MSSA476 UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase YP_043014.1 976427 D 282459 CDS YP_043015.1 49485794 2863082 977901..978152 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0989; hypothetical protein 978152 2863082 SAS0888 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043015.1 977901 D 282459 CDS YP_043016.1 49485795 2863083 978152..979714 1 NC_002953.3 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 979714 prfC 2863083 prfC Staphylococcus aureus subsp. aureus MSSA476 peptide chain release factor 3 YP_043016.1 978152 D 282459 CDS YP_043017.1 49485796 2862357 980016..980819 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0991; hypothetical protein 980819 2862357 SAS0890 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043017.1 980016 D 282459 CDS YP_043018.1 49485797 2862304 complement(981108..982313) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1562; phage integrase 982313 2862304 SAS0891 Staphylococcus aureus subsp. aureus MSSA476 phage integrase YP_043018.1 981108 R 282459 CDS YP_043019.1 49485798 2862305 982440..983063 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1561; hypothetical protein 983063 2862305 SAS0892 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043019.1 982440 D 282459 CDS YP_043020.1 49485799 2863972 complement(983050..983172) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1560; hypothetical protein 983172 2863972 SAS0893 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043020.1 983050 R 282459 CDS YP_043021.1 49485800 2862352 complement(983262..983657) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1559; hypothetical protein 983657 2862352 SAS0894 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043021.1 983262 R 282459 CDS YP_043022.1 49485801 2862353 complement(983686..984120) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1558; lipoprotein 984120 2862353 SAS0895 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_043022.1 983686 R 282459 CDS YP_043023.1 49485802 2861886 complement(984138..984599) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1557; hypothetical protein 984599 2861886 SAS0896 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043023.1 984138 R 282459 CDS YP_043024.1 49485803 2861887 complement(984612..984941) 1 NC_002953.3 Similar to Bacteriophage A118 repressor protein SWALL:Q9T188 (EMBL:AJ242593) (101 aa) fasta scores: E(): 0.00012, 32.65% id in 98 aa, and to Enterococcus faecalis transcriptional regulator, Cro/CI family ef1422 SWALL:Q835F5 (EMBL:AE016951) (107 aa) fasta scores: E(): 0.00014, 33.01% id in 106 aa; phage regulatory protein 984941 2861887 SAS0897 Staphylococcus aureus subsp. aureus MSSA476 phage regulatory protein YP_043024.1 984612 R 282459 CDS YP_043025.1 49485804 2862230 985093..985293 1 NC_002953.3 Similar to Lactococcus phage BK5-T Cro repressor SWALL:Q38329 (EMBL:AF176025) (79 aa) fasta scores: E(): 0.016, 33.33% id in 60 aa, and to Streptococcus pyogenes, Streptococcus pyogenes Cro-like repressor protein-phage associated spy1485 or spym18_1503 or spym3_1142 or sps0720 SWALL:Q99YY6 (EMBL:AE006582) (70 aa) fasta scores: E(): 0.034, 36.95% id in 46 aa; phage regulatory protein 985293 2862230 SAS0898 Staphylococcus aureus subsp. aureus MSSA476 phage regulatory protein YP_043025.1 985093 D 282459 CDS YP_043026.1 49485805 2861933 985377..985553 1 NC_002953.3 hypothetical protein 985553 2861933 SAS0899 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043026.1 985377 D 282459 CDS YP_043027.1 49485806 2861934 complement(985550..985789) 1 NC_002953.3 Similar to Sulfolobus sp. NOB8H2 hypothetical protein SWALL:O93686 (EMBL:AJ010405) (72 aa) fasta scores: E(): 0.98, 37.03% id in 54 aa; hypothetical protein 985789 2861934 SAS0900 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043027.1 985550 R 282459 CDS YP_043028.1 49485807 2863628 985836..986051 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1548; hypothetical protein 986051 2863628 SAS0901 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043028.1 985836 D 282459 CDS YP_043029.1 49485808 2863182 986076..986339 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1547; DNA-binding protein 986339 2863182 SAS0902 Staphylococcus aureus subsp. aureus MSSA476 DNA-binding protein YP_043029.1 986076 D 282459 CDS YP_043030.1 49485809 2863183 986351..986512 1 NC_002953.3 Similar to Staphylococcus aureus phage phi 13 phi PVL orf 38-like protein SWALL:Q8SDM7 (EMBL:AF424783) (53 aa) fasta scores: E(): 2.8e-20, 92.45% id in 53 aa, and to Staphylococcus aureus prophage phiPV83 phi PVL orf 38 homologue SWALL:Q9MBS6 (EMBL:AB044554) (55 aa) fasta scores: E(): 9e-20, 94.23% id in 52 aa; hypothetical protein 986512 2863183 SAS0903 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043030.1 986351 D 282459 CDS YP_043031.1 49485810 2861986 986905..987165 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2088; hypothetical protein 987165 2861986 SAS0905 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043031.1 986905 D 282459 CDS YP_043032.1 49485811 2864171 987179..987541 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1544; hypothetical protein 987541 2864171 SAS0906 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043032.1 987179 D 282459 CDS YP_043033.1 49485812 2862238 987538..988704 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1543; hypothetical protein 988704 2862238 SAS0907 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043033.1 987538 D 282459 CDS YP_043034.1 49485813 2862239 988730..989287 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1542; hypothetical protein 989287 2862239 SAS0908 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043034.1 988730 D 282459 CDS YP_043035.1 49485814 2863233 989347..991308 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1541; DNA polymerase 991308 2863233 SAS0909 Staphylococcus aureus subsp. aureus MSSA476 DNA polymerase YP_043035.1 989347 D 282459 CDS YP_043036.1 49485815 2862812 991321..991506 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1540; hypothetical protein 991506 2862812 SAS0910 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043036.1 991321 D 282459 CDS YP_043037.1 49485816 2862813 991506..991907 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1539; DNA-binding protein 991907 2862813 SAS0911 Staphylococcus aureus subsp. aureus MSSA476 DNA-binding protein YP_043037.1 991506 D 282459 CDS YP_043038.1 49485817 2863722 991907..992161 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1538; hypothetical protein 992161 2863722 SAS0912 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043038.1 991907 D 282459 CDS YP_043039.1 49485818 2863723 992167..992409 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2076; hypothetical protein 992409 2863723 SAS0913 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043039.1 992167 D 282459 CDS YP_043040.1 49485819 2863770 992423..992629 1 NC_002953.3 Similar to N-terminal region of Staphylococcus aureus phage phi 12 PVL orf 52-like protein SWALL:Q8SDR1 (EMBL:AF424782) (133 aa) fasta scores: E(): 5.1e-07, 43.28% id in 67 aa; hypothetical protein 992629 2863770 SAS0914 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043040.1 992423 D 282459 CDS YP_043041.1 49485820 2862167 992632..993036 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1535; hypothetical protein 993036 2862167 SAS0915 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043041.1 992632 D 282459 CDS YP_043042.1 49485821 2862168 993033..993380 1 NC_002953.3 Identical to Staphylococcus aureus phage phi 12 hypothetical phage protein SWALL:Q8SBD5 (EMBL:AF424782) (115 aa) fasta scores: E(): 4.2e-42, 100% id in 115 aa; hypothetical protein 993380 2862168 SAS0916 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043042.1 993033 D 282459 CDS YP_043043.1 49485822 2862026 993377..993685 1 NC_002953.3 Highly similar to Staphylococcus aureus phage phi 12 PV83 orf 27-like protein SWALL:Q8SDR0 (EMBL:AF424782) (102 aa) fasta scores: E(): 1.3e-33, 97.05% id in 102 aa; hypothetical protein 993685 2862026 SAS0917 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043043.1 993377 D 282459 CDS YP_043044.1 49485823 2863934 993678..993926 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2074; hypothetical protein 993926 2863934 SAS0918 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043044.1 993678 D 282459 CDS YP_043045.1 49485824 2863935 993919..994455 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1531; hypothetical protein 994455 2863935 SAS0919 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043045.1 993919 D 282459 CDS YP_043046.1 49485825 2863950 994492..994665 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1530; hypothetical protein 994665 2863950 SAS0920 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043046.1 994492 D 282459 CDS YP_043047.1 49485826 2863951 994682..994876 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2071; hypothetical protein 994876 2863951 SAS0921 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043047.1 994682 D 282459 CDS YP_043048.1 49485827 2862152 994876..995400 1 NC_002953.3 hypothetical protein 995400 2862152 SAS0922 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043048.1 994876 D 282459 CDS YP_043049.1 49485828 2863124 995448..995600 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1527; hypothetical protein 995600 2863124 SAS0923 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043049.1 995448 D 282459 CDS YP_043051.1 49485830 2863944 995668..995868 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1526; exported phage protein 995868 2863944 SAS0924 Staphylococcus aureus subsp. aureus MSSA476 exported phage protein YP_043051.1 995668 D 282459 CDS YP_043052.1 49485831 2863801 complement(995895..996101) 1 NC_002953.3 Poor database matches. Weakly similar to Pyrococcus horikoshii hypothetical upf0248 protein PH1212.1 SWALL:YC1A_PYRHO (SWALL:P59734) (83 aa) fasta scores: E(): 4.5, 27.53% id in 69 aa; hypothetical protein 996101 2863801 SAS0925 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043052.1 995895 R 282459 CDS YP_043053.1 49485832 2863802 996156..998603 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1525; hypothetical protein 998603 2863802 SAS0926 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043053.1 996156 D 282459 CDS YP_043054.1 49485833 2862836 998944..999234 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1524; hypothetical protein 999234 2862836 SAS0927 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043054.1 998944 D 282459 CDS YP_043055.1 49485834 2862837 999224..1000591 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1523; hypothetical protein 1000591 2862837 SAS0928 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043055.1 999224 D 282459 CDS YP_043056.1 49485835 2863216 1000604..1001041 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1522; phage regulatory protein 1001041 2863216 SAS0929 Staphylococcus aureus subsp. aureus MSSA476 phage regulatory protein YP_043056.1 1000604 D 282459 CDS YP_043057.1 49485836 2863192 1001202..1001522 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1521; hypothetical protein 1001522 2863192 SAS0930 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043057.1 1001202 D 282459 CDS YP_043058.1 49485837 2863193 1001648..1001953 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1520; terminase small subunit 1001953 2863193 SAS0931 Staphylococcus aureus subsp. aureus MSSA476 terminase small subunit YP_043058.1 1001648 D 282459 CDS YP_043059.1 49485838 2863126 1001934..1003634 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1519; terminase large subunit 1003634 2863126 SAS0932 Staphylococcus aureus subsp. aureus MSSA476 terminase large subunit YP_043059.1 1001934 D 282459 CDS YP_043060.1 49485839 2863834 1003639..1004877 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1518; portal protein 1004877 2863834 SAS0933 Staphylococcus aureus subsp. aureus MSSA476 portal protein YP_043060.1 1003639 D 282459 CDS YP_043061.1 49485840 2863835 1004861..1005634 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1517; phage protease 1005634 2863835 SAS0934 Staphylococcus aureus subsp. aureus MSSA476 phage protease YP_043061.1 1004861 D 282459 CDS YP_043062.1 49485841 2862437 1005646..1006809 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1516; hypothetical protein 1006809 2862437 SAS0935 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043062.1 1005646 D 282459 CDS YP_043063.1 49485842 2862438 1006878..1007156 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1515; hypothetical protein 1007156 2862438 SAS0936 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043063.1 1006878 D 282459 CDS YP_043064.1 49485843 2862421 1007168..1007500 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1514; hypothetical protein 1007500 2862421 SAS0937 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043064.1 1007168 D 282459 CDS YP_043065.1 49485844 2863209 1007527..1007898 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1513; hypothetical protein 1007898 2863209 SAS0938 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043065.1 1007527 D 282459 CDS YP_043066.1 49485845 2863210 1007899..1008294 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1512; hypothetical protein 1008294 2863210 SAS0939 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043066.1 1007899 D 282459 CDS YP_043067.1 49485846 2862488 1008329..1008970 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1511; major tail protein 1008970 2862488 SAS0940 Staphylococcus aureus subsp. aureus MSSA476 major tail protein YP_043067.1 1008329 D 282459 CDS YP_043068.1 49485847 2862495 1009062..1009517 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1510; major tail protein 1009517 2862495 SAS0941 Staphylococcus aureus subsp. aureus MSSA476 major tail protein YP_043068.1 1009062 D 282459 CDS YP_043069.1 49485848 2862496 1009575..1009925 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1509; hypothetical protein 1009925 2862496 SAS0942 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043069.1 1009575 D 282459 CDS YP_043070.1 49485849 2862924 1009967..1010125 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1508; hypothetical protein 1010125 2862924 SAS0943 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043070.1 1009967 D 282459 CDS YP_043071.1 49485850 2862925 1010139..1016339 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1507; hypothetical protein 1016339 2862925 SAS0944 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043071.1 1010139 D 282459 CDS YP_043072.1 49485851 2862492 1016339..1017163 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1506; hypothetical protein 1017163 2862492 SAS0945 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043072.1 1016339 D 282459 CDS YP_043073.1 49485852 2862929 1017172..1018755 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1505; hypothetical protein 1018755 2862929 SAS0946 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043073.1 1017172 D 282459 CDS YP_043074.1 49485853 2863321 1018755..1019045 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1504; hypothetical protein 1019045 2863321 SAS0947 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043074.1 1018755 D 282459 CDS YP_043075.1 49485854 2863158 1019061..1020971 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1503; hypothetical protein 1020971 2863158 SAS0948 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043075.1 1019061 D 282459 CDS YP_043076.1 49485855 2862934 1020971..1022437 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1502; hypothetical protein 1022437 2862934 SAS0949 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043076.1 1020971 D 282459 CDS YP_043077.1 49485856 2862935 1022437..1022826 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1501; hypothetical protein 1022826 2862935 SAS0950 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043077.1 1022437 D 282459 CDS YP_043078.1 49485857 2862854 1022819..1022983 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1500; hypothetical protein 1022983 2862854 SAS0951 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043078.1 1022819 D 282459 CDS YP_043079.1 49485858 2862855 1023029..1023328 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1499; hypothetical protein 1023328 2862855 SAS0952 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043079.1 1023029 D 282459 CDS YP_043080.1 49485859 2862887 1023464..1023766 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1498; holin 1023766 2862887 SAS0953 Staphylococcus aureus subsp. aureus MSSA476 holin YP_043080.1 1023464 D 282459 CDS YP_043081.1 49485860 2862990 1023777..1025231 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1497; amidase 1025231 2862990 SAS0954 Staphylococcus aureus subsp. aureus MSSA476 amidase YP_043081.1 1023777 D 282459 CDS YP_043082.1 49485861 2862991 1025807..1028116 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0992; protease 1028116 2862991 SAS0955 Staphylococcus aureus subsp. aureus MSSA476 protease YP_043082.1 1025807 D 282459 CDS YP_043083.1 49485862 2862996 1028133..1029491 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0993; sodium transport protein 1029491 2862996 SAS0956 Staphylococcus aureus subsp. aureus MSSA476 sodium transport protein YP_043083.1 1028133 D 282459 CDS YP_043084.1 49485863 2863546 1029627..1031141 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0994; 5'-nucleotidase 1031141 2863546 SAS0957 Staphylococcus aureus subsp. aureus MSSA476 5'-nucleotidase YP_043084.1 1029627 D 282459 CDS YP_043085.1 49485864 2863547 complement(1031628..1032197) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0995; regulatory protein 1032197 2863547 SAS0958 Staphylococcus aureus subsp. aureus MSSA476 regulatory protein YP_043085.1 1031628 R 282459 CDS YP_043086.1 49485865 2862997 1032398..1032625 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0996; hypothetical protein 1032625 2862997 SAS0959 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043086.1 1032398 D 282459 CDS YP_043087.1 49485866 2862998 complement(1032706..1033692) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0997; lipoate-protein ligase A 1033692 2862998 SAS0960 Staphylococcus aureus subsp. aureus MSSA476 lipoate-protein ligase A YP_043087.1 1032706 R 282459 CDS YP_043088.1 49485867 2864016 1033891..1034067 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0998; hypothetical protein 1034067 2864016 SAS0961 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043088.1 1033891 D 282459 CDS YP_043089.1 49485868 2862940 1034082..1034684 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0999; hypothetical protein 1034684 2862940 SAS0962 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043089.1 1034082 D 282459 CDS YP_043090.1 49485869 2862941 1034895..1035002 1 NC_002953.3 No significant database matches. Doubtful CDS; hypothetical protein 1035002 2862941 SAS0963 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043090.1 1034895 D 282459 CDS YP_043091.1 49485870 2863523 <1035643..1035924 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1001; hypothetical protein 1035924 2863523 SAS0964 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043091.1 <1035643 D 282459 CDS YP_043092.1 49485871 2864034 1037934..1038254 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1003; hypothetical protein 1038254 2864034 SAS0967 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043092.1 1037934 D 282459 CDS YP_043093.1 49485872 2862109 1038251..1038892 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1004; ABC transporter ATP-binding protein 1038892 2862109 SAS0968 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_043093.1 1038251 D 282459 CDS YP_043094.1 49485873 2862110 complement(1038980..1039270) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1005; hypothetical protein 1039270 2862110 SAS0969 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043094.1 1038980 R 282459 CDS YP_043095.1 49485874 2861773 1039611..1039898 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1007; hypothetical protein 1039898 2861773 SAS0970 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043095.1 1039611 D 282459 CDS YP_043096.1 49485875 2864376 1039904..1041385 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1008; glycosyl transferase family protein 1041385 2864376 SAS0971 Staphylococcus aureus subsp. aureus MSSA476 glycosyl transferase family protein YP_043096.1 1039904 D 282459 CDS YP_043097.1 49485876 2864377 complement(1041474..1041830) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1010; hypothetical protein 1041830 2864377 SAS0972 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043097.1 1041474 R 282459 CDS YP_043098.1 49485877 2864028 1042318..1043277 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1011; transport system extracellular binding lipoprotein 1043277 2864028 SAS0973 Staphylococcus aureus subsp. aureus MSSA476 transport system extracellular binding lipoprotein YP_043098.1 1042318 D 282459 CDS YP_043099.1 49485878 2864383 complement(1043323..1043439) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1012; hypothetical protein 1043439 2864383 SAS0974 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043099.1 1043323 R 282459 CDS YP_043100.1 49485879 2864384 complement(1043518..1043733) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1013; hypothetical protein 1043733 2864384 SAS0975 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043100.1 1043518 R 282459 CDS YP_043101.1 49485880 2864413 1043898..1044449 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1014; hypothetical protein 1044449 2864413 SAS0976 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043101.1 1043898 D 282459 CDS YP_043102.1 49485881 2864414 complement(1044500..1045438) 1 NC_002953.3 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 1045438 2864414 SAS0977 Staphylococcus aureus subsp. aureus MSSA476 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_043102.1 1044500 R 282459 CDS YP_043103.1 49485882 2864393 1045611..1046981 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1016; chorismate binding protein 1046981 2864393 SAS0978 Staphylococcus aureus subsp. aureus MSSA476 chorismate binding protein YP_043103.1 1045611 D 282459 CDS YP_043104.1 49485883 2864385 1046968..1048641 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1017; menaquinone biosynthesis bifunctional protein 1048641 2864385 SAS0979 Staphylococcus aureus subsp. aureus MSSA476 menaquinone biosynthesis bifunctional protein YP_043104.1 1046968 D 282459 CDS YP_043105.1 49485884 2864386 1048628..1049431 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1018; hydrolase 1049431 2864386 SAS0980 Staphylococcus aureus subsp. aureus MSSA476 hydrolase YP_043105.1 1048628 D 282459 CDS YP_043106.1 49485885 2864460 1049424..1050245 1 NC_002953.3 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 1050245 2864460 SAS0981 Staphylococcus aureus subsp. aureus MSSA476 naphthoate synthase YP_043106.1 1049424 D 282459 CDS YP_043107.1 49485886 2864398 complement(1050483..1050812) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1020; hypothetical protein 1050812 2864398 SAS0982 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043107.1 1050483 R 282459 CDS YP_043108.1 49485887 2864399 complement(1050850..1052031) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1021; cysteine protease precursor 1052031 2864399 SAS0983 Staphylococcus aureus subsp. aureus MSSA476 cysteine protease precursor YP_043108.1 1050850 R 282459 CDS YP_043109.1 49485888 2862506 complement(1052113..1053114) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1022; glutamyl endopeptidase precursor 1053114 2862506 SAS0984 Staphylococcus aureus subsp. aureus MSSA476 glutamyl endopeptidase precursor YP_043109.1 1052113 R 282459 CDS YP_043110.1 49485889 2862688 complement(1053642..1054796) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1023; aminotransferase 1054796 2862688 SAS0985 Staphylococcus aureus subsp. aureus MSSA476 aminotransferase YP_043110.1 1053642 R 282459 CDS YP_043111.1 49485890 2864002 complement(1054992..1056002) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1024; hypothetical protein 1056002 2864002 SAS0986 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043111.1 1054992 R 282459 CDS YP_043112.1 49485891 2862751 1056155..1056574 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1025; MarR family transcriptional regulator 1056574 2862751 SAS0987 Staphylococcus aureus subsp. aureus MSSA476 MarR family transcriptional regulator YP_043112.1 1056155 D 282459 CDS YP_043113.1 49485892 2862752 complement(1056781..1060533) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1026; bifunctional autolysin precursor 1060533 2862752 SAS0988 Staphylococcus aureus subsp. aureus MSSA476 bifunctional autolysin precursor YP_043113.1 1056781 R 282459 CDS YP_043114.1 49485893 2862743 complement(1060761..1061195) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1027; acetyltransferase (GNAT) family protein 1061195 2862743 SAS0989 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase (GNAT) family protein YP_043114.1 1060761 R 282459 CDS YP_043115.1 49485894 2863268 complement(1061350..1061820) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1028; hypothetical protein 1061820 2863268 SAS0990 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043115.1 1061350 R 282459 CDS YP_043116.1 49485895 2863269 complement(1061868..1063085) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1029; hypothetical protein 1063085 2863269 SAS0991 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043116.1 1061868 R 282459 CDS YP_043117.1 49485896 2864012 1063536..1064729 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1030; autolysis and methicillin resistant-related protein 1064729 2864012 SAS0992 Staphylococcus aureus subsp. aureus MSSA476 autolysis and methicillin resistant-related protein YP_043117.1 1063536 D 282459 CDS YP_043118.1 49485897 2864013 complement(1065266..1065556) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1031; quinol oxidase polypeptide IV 1065556 2864013 SAS0993 Staphylococcus aureus subsp. aureus MSSA476 quinol oxidase polypeptide IV YP_043118.1 1065266 R 282459 CDS YP_043119.1 49485898 2862869 complement(1065553..1066158) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1032; quinol oxidase polypeptide III 1066158 2862869 SAS0994 Staphylococcus aureus subsp. aureus MSSA476 quinol oxidase polypeptide III YP_043119.1 1065553 R 282459 CDS YP_043120.1 49485899 2863279 complement(1066148..1068136) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1033; quinol oxidase polypeptide I 1068136 2863279 SAS0995 Staphylococcus aureus subsp. aureus MSSA476 quinol oxidase polypeptide I YP_043120.1 1066148 R 282459 CDS YP_043121.1 49485900 2863280 complement(1068136..1069236) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1034; quinol oxidase polypeptide II precursor 1069236 2863280 SAS0996 Staphylococcus aureus subsp. aureus MSSA476 quinol oxidase polypeptide II precursor YP_043121.1 1068136 R 282459 CDS YP_043122.1 49485901 2863270 complement(1069808..1070125) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1035; hypothetical protein 1070125 2863270 SAS0997 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043122.1 1069808 R 282459 CDS YP_043123.1 49485902 2863352 complement(1070908..1071768) 1 NC_002953.3 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 1071768 2863352 SAS0999 Staphylococcus aureus subsp. aureus MSSA476 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_043123.1 1070908 R 282459 CDS YP_043124.1 49485903 2863353 1071969..1072451 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1038; phosphoribosylaminoimidazole carboxylase catalytic subunit 1072451 2863353 SAS1000 Staphylococcus aureus subsp. aureus MSSA476 phosphoribosylaminoimidazole carboxylase catalytic subunit YP_043124.1 1071969 D 282459 CDS YP_043125.1 49485904 2862668 1072438..1073562 1 NC_002953.3 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1073562 2862668 SAS1001 Staphylococcus aureus subsp. aureus MSSA476 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_043125.1 1072438 D 282459 CDS YP_043126.1 49485905 2862669 1073566..1074270 1 NC_002953.3 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 1074270 2862669 SAS1002 Staphylococcus aureus subsp. aureus MSSA476 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_043126.1 1073566 D 282459 CDS YP_043127.1 49485906 2863286 1074270..1074533 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1041; hypothetical protein 1074533 2863286 SAS1003 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043127.1 1074270 D 282459 CDS YP_043128.1 49485907 2862670 1074535..1075206 1 NC_002953.3 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 1075206 2862670 SAS1004 Staphylococcus aureus subsp. aureus MSSA476 phosphoribosylformylglycinamidine synthase I YP_043128.1 1074535 D 282459 CDS YP_043129.1 49485908 2862671 1075199..1077388 1 NC_002953.3 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 1077388 2862671 SAS1005 Staphylococcus aureus subsp. aureus MSSA476 phosphoribosylformylglycinamidine synthase II YP_043129.1 1075199 D 282459 CDS YP_043130.1 49485909 2863434 1077367..1078851 1 NC_002953.3 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 1078851 2863434 SAS1006 Staphylococcus aureus subsp. aureus MSSA476 amidophosphoribosyltransferase YP_043130.1 1077367 D 282459 CDS YP_043131.1 49485910 2863427 1078844..1079872 1 NC_002953.3 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 1079872 2863427 SAS1007 Staphylococcus aureus subsp. aureus MSSA476 phosphoribosylaminoimidazole synthetase YP_043131.1 1078844 D 282459 CDS YP_043132.1 49485911 2863428 1079875..1080441 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1046; phosphoribosylglycinamide formyltransferase 1080441 2863428 SAS1008 Staphylococcus aureus subsp. aureus MSSA476 phosphoribosylglycinamide formyltransferase YP_043132.1 1079875 D 282459 CDS YP_043133.1 49485912 2863491 1080456..1081934 1 NC_002953.3 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1081934 purH 2863491 purH Staphylococcus aureus subsp. aureus MSSA476 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_043133.1 1080456 D 282459 CDS YP_043134.1 49485913 2863492 1081956..1083203 1 NC_002953.3 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 1083203 2863492 SAS1010 Staphylococcus aureus subsp. aureus MSSA476 phosphoribosylamine--glycine ligase YP_043134.1 1081956 D 282459 CDS YP_043135.1 49485914 2862620 complement(1083468..1084289) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1049; cobalt transport protein 1084289 2862620 SAS1011 Staphylococcus aureus subsp. aureus MSSA476 cobalt transport protein YP_043135.1 1083468 R 282459 CDS YP_043136.1 49485915 2863471 complement(1084267..1085667) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1050; ABC transporter ATP-binding protein 1085667 2863471 SAS1012 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_043136.1 1084267 R 282459 CDS YP_043137.1 49485916 2863472 complement(1085682..1086257) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1051; hypothetical protein 1086257 2863472 SAS1013 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043137.1 1085682 R 282459 CDS YP_043138.1 49485917 2863222 complement(1086841..1086975) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1052; hypothetical protein 1086975 2863222 SAS1014 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043138.1 1086841 R 282459 CDS YP_043139.1 49485918 2863646 1087127..1088422 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1053; hypothetical protein 1088422 2863646 SAS1015 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043139.1 1087127 D 282459 CDS YP_043140.1 49485919 2863647 1088847..1090019 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1054; hypothetical protein 1090019 2863647 SAS1016 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043140.1 1088847 D 282459 CDS YP_043141.1 49485920 2863066 1090073..1090615 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1055; hypothetical protein 1090615 2863066 SAS1017 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043141.1 1090073 D 282459 CDS YP_043142.1 49485921 2863067 1090769..1091035 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1056; phosphocarrier protein HPr 1091035 2863067 SAS1018 Staphylococcus aureus subsp. aureus MSSA476 phosphocarrier protein HPr YP_043142.1 1090769 D 282459 CDS YP_043143.1 49485922 2864072 1091038..1092756 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1057; phosphoenolpyruvate-protein phosphotransferase 1092756 2864072 SAS1019 Staphylococcus aureus subsp. aureus MSSA476 phosphoenolpyruvate-protein phosphotransferase YP_043143.1 1091038 D 282459 CDS YP_043144.1 49485923 2864073 complement(1092993..1093226) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1058; glutaredoxin 1093226 2864073 SAS1020 Staphylococcus aureus subsp. aureus MSSA476 glutaredoxin YP_043144.1 1092993 R 282459 CDS YP_043145.1 49485924 2864074 1093424..1094785 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1059; cytochrome ubiquinol oxidase 1094785 2864074 SAS1021 Staphylococcus aureus subsp. aureus MSSA476 cytochrome ubiquinol oxidase YP_043145.1 1093424 D 282459 CDS YP_043146.1 49485925 2864079 1094782..1095801 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1060; hypothetical protein 1095801 2864079 SAS1022 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043146.1 1094782 D 282459 CDS YP_043147.1 49485926 2864092 1095934..1096596 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1061; potassium transport protein 1096596 2864092 SAS1023 Staphylococcus aureus subsp. aureus MSSA476 potassium transport protein YP_043147.1 1095934 D 282459 CDS YP_043148.1 49485927 2864093 complement(1096945..1098642) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1063; hypothetical protein 1098642 2864093 SAS1024 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043148.1 1096945 R 282459 CDS YP_043149.1 49485928 2864090 complement(1098642..1098860) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1064; hypothetical protein 1098860 2864090 SAS1025 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043149.1 1098642 R 282459 CDS YP_043150.1 49485929 2864091 complement(1099342..1099893) 1 NC_002953.3 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1099893 def 2864091 def Staphylococcus aureus subsp. aureus MSSA476 peptide deformylase YP_043150.1 1099342 R 282459 CDS YP_043151.1 49485930 2864315 1100258..1100884 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1066; hypothetical protein 1100884 2864315 SAS1027 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043151.1 1100258 D 282459 CDS YP_043152.1 49485931 2864107 1101055..1102167 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1067; pyruvate dehydrogenase E1 component subunit alpha 1102167 2864107 SAS1028 Staphylococcus aureus subsp. aureus MSSA476 pyruvate dehydrogenase E1 component subunit alpha YP_043152.1 1101055 D 282459 CDS YP_043153.1 49485932 2864108 1102171..1103148 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1068; pyruvate dehydrogenase E1 component subunit beta 1103148 2864108 SAS1029 Staphylococcus aureus subsp. aureus MSSA476 pyruvate dehydrogenase E1 component subunit beta YP_043153.1 1102171 D 282459 CDS YP_043154.1 49485933 2864285 1103239..1104531 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1069; branched-chain alpha-keto acid dehydrogenase E2 1104531 2864285 SAS1030 Staphylococcus aureus subsp. aureus MSSA476 branched-chain alpha-keto acid dehydrogenase E2 YP_043154.1 1103239 D 282459 CDS YP_043155.1 49485934 2864342 1104535..1105941 1 NC_002953.3 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1105941 2864342 SAS1031 Staphylococcus aureus subsp. aureus MSSA476 dihydrolipoamide dehydrogenase YP_043155.1 1104535 D 282459 CDS YP_043156.1 49485935 2864343 1106109..1106384 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1071; hypothetical protein 1106384 2864343 SAS1032 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043156.1 1106109 D 282459 CDS YP_043157.1 49485936 2864286 1106528..1107067 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1072; DNA-binding protein 1107067 2864286 SAS1033 Staphylococcus aureus subsp. aureus MSSA476 DNA-binding protein YP_043157.1 1106528 D 282459 CDS YP_043158.1 49485937 2864287 1107080..1108174 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1073; ABC transporter ATP binding protein 1108174 2864287 SAS1034 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP binding protein YP_043158.1 1107080 D 282459 CDS YP_043159.1 49485938 2864149 1108167..1108964 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1074; ABC transporter permease 1108964 2864149 SAS1035 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter permease YP_043159.1 1108167 D 282459 CDS YP_043160.1 49485939 2863097 1108970..1109779 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1075; ABC transporter permease 1109779 2863097 SAS1036 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter permease YP_043160.1 1108970 D 282459 CDS YP_043161.1 49485940 2863098 1109779..1110852 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1076; ABC transporter extracellular binding protein 1110852 2863098 SAS1037 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter extracellular binding protein YP_043161.1 1109779 D 282459 CDS YP_043162.1 49485941 2862242 1110926..1111945 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1077; hypothetical protein 1111945 2862242 SAS1038 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043162.1 1110926 D 282459 CDS YP_043163.1 49485942 2861880 1112228..1112647 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1078; hypothetical protein 1112647 2861880 SAS1039 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043163.1 1112228 D 282459 CDS YP_043164.1 49485943 2861881 complement(1112729..1114081) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1079; manganese transport protein MntH 1114081 2861881 SAS1040 Staphylococcus aureus subsp. aureus MSSA476 manganese transport protein MntH YP_043164.1 1112729 R 282459 CDS YP_043165.1 49485944 2864182 complement(1114265..1114879) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1080; hypothetical protein 1114879 2864182 SAS1041 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043165.1 1114265 R 282459 CDS YP_043166.1 49485945 2864183 1115036..1115863 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1081; inositol monophosphatase 1115863 2864183 SAS1042 Staphylococcus aureus subsp. aureus MSSA476 inositol monophosphatase YP_043166.1 1115036 D 282459 CDS YP_043167.1 49485946 2862585 complement(1116017..1116208) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1082; hypothetical protein 1116208 2862585 SAS1043 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043167.1 1116017 R 282459 CDS YP_043168.1 49485947 2861878 1116310..1118157 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1083; BipA family GTPase 1118157 2861878 SAS1044 Staphylococcus aureus subsp. aureus MSSA476 BipA family GTPase YP_043168.1 1116310 D 282459 CDS YP_043169.1 49485948 2861879 complement(1118297..1118464) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1084; hypothetical protein 1118464 2861879 SAS1045 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043169.1 1118297 R 282459 CDS YP_043170.1 49485949 2862591 complement(1118466..1118948) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1085; hypothetical protein 1118948 2862591 SAS1046 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043170.1 1118466 R 282459 CDS YP_043171.1 49485950 2862018 1119089..1119364 1 NC_002953.3 depletion of this protein in Bacillus subtilis results in defects in cell morphology; crystal structure of Staphylococcus protein shows homodimer; ligand binding protein; hypothetical protein 1119364 2862018 SAS1047 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043171.1 1119089 D 282459 CDS YP_043172.1 49485951 2862019 1119678..1120904 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1087; cell division protein 1120904 2862019 SAS1048 Staphylococcus aureus subsp. aureus MSSA476 cell division protein YP_043172.1 1119678 D 282459 CDS YP_043173.1 49485952 2864190 1121458..1124910 1 NC_002953.3 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 1124910 2864190 SAS1049 Staphylococcus aureus subsp. aureus MSSA476 pyruvate carboxylase YP_043173.1 1121458 D 282459 CDS YP_043174.1 49485953 2864191 complement(1125050..1125961) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1089; heme A synthase 1125961 2864191 SAS1050 Staphylococcus aureus subsp. aureus MSSA476 heme A synthase YP_043174.1 1125050 R 282459 CDS YP_043175.1 49485954 2863888 1126401..1127312 1 NC_002953.3 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 1127312 2863888 SAS1051 Staphylococcus aureus subsp. aureus MSSA476 protoheme IX farnesyltransferase YP_043175.1 1126401 D 282459 CDS YP_043176.1 49485955 2861953 1127337..1127798 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1091; hypothetical protein 1127798 2861953 SAS1052 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043176.1 1127337 D 282459 CDS YP_043177.1 49485956 2861954 1128125..1129162 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1092; hypothetical protein 1129162 2861954 SAS1053 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043177.1 1128125 D 282459 CDS YP_043178.1 49485957 2862008 1129178..1129612 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1093; hypothetical protein 1129612 2862008 SAS1054 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043178.1 1129178 D 282459 CDS YP_043179.1 49485958 2863702 complement(1129675..1130601) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1094; hypothetical protein 1130601 2863702 SAS1055 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043179.1 1129675 R 282459 CDS YP_043180.1 49485959 2863703 1130840..1131094 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1095; hypothetical protein 1131094 2863703 SAS1056 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043180.1 1130840 D 282459 CDS YP_043181.1 49485960 2863975 complement(1131097..1131486) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1096; hypothetical protein 1131486 2863975 SAS1057 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043181.1 1131097 R 282459 CDS YP_043182.1 49485961 2863976 1131556..1132098 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1097; methylase 1132098 2863976 SAS1058 Staphylococcus aureus subsp. aureus MSSA476 methylase YP_043182.1 1131556 D 282459 CDS YP_043183.1 49485962 2863962 1132100..1132582 1 NC_002953.3 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1132582 coaD 2863962 coaD Staphylococcus aureus subsp. aureus MSSA476 phosphopantetheine adenylyltransferase YP_043183.1 1132100 D 282459 CDS YP_043184.1 49485963 2862520 complement(1132644..1133783) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1099; hypothetical protein 1133783 2862520 SAS1060 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043184.1 1132644 R 282459 CDS YP_043185.1 49485964 2862521 1133910..1134467 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1100; hypothetical protein 1134467 2862521 SAS1061 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043185.1 1133910 D 282459 CDS YP_043186.1 49485965 2864370 1134547..1134720 1 NC_002953.3 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1134720 rpmF 2864370 rpmF Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L32 YP_043186.1 1134547 D 282459 CDS YP_043187.1 49485966 2864365 complement(1134874..1136811) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1102; iron-regulated heme-iron binding protein 1136811 2864365 SAS1063 Staphylococcus aureus subsp. aureus MSSA476 iron-regulated heme-iron binding protein YP_043187.1 1134874 R 282459 CDS YP_043188.1 49485967 2864366 complement(1137014..1138066) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1103; iron-regulated heme-iron binding protein 1138066 2864366 SAS1064 Staphylococcus aureus subsp. aureus MSSA476 iron-regulated heme-iron binding protein YP_043188.1 1137014 R 282459 CDS YP_043189.1 49485968 2862597 1138275..1138958 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1104; surface anchored protein 1138958 2862597 SAS1065 Staphylococcus aureus subsp. aureus MSSA476 surface anchored protein YP_043189.1 1138275 D 282459 CDS YP_043190.1 49485969 2863599 1138958..1140034 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1105; hypothetical protein 1140034 2863599 SAS1066 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043190.1 1138958 D 282459 CDS YP_043191.1 49485970 2863232 1140031..1140909 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1106; transport system extracellular binding lipoprotein 1140909 2863232 SAS1067 Staphylococcus aureus subsp. aureus MSSA476 transport system extracellular binding lipoprotein YP_043191.1 1140031 D 282459 CDS YP_043192.1 49485971 2863911 1140919..1141887 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1107; iron/heme permease 1141887 2863911 SAS1068 Staphylococcus aureus subsp. aureus MSSA476 iron/heme permease YP_043192.1 1140919 D 282459 CDS YP_043193.1 49485972 2863912 1141949..1142683 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1108; sortase 1142683 2863912 SAS1069 Staphylococcus aureus subsp. aureus MSSA476 sortase YP_043193.1 1141949 D 282459 CDS YP_043194.1 49485973 2862706 1142702..1143025 1 NC_002953.3 iron regulated; catalyzes the release of heme from hemoglobin allowing bacterial pathogens to use the host heme as an iron source; heme-degrading monooxygenase IsdG 1143025 2862706 SAS1070 Staphylococcus aureus subsp. aureus MSSA476 heme-degrading monooxygenase IsdG YP_043194.1 1142702 D 282459 CDS YP_043195.1 49485974 2861929 1143062..1143169 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1109a; Doubtful CDS. No database matches; hypothetical protein 1143169 2861929 SAS1070a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043195.1 1143062 D 282459 CDS YP_043196.1 49485975 2861930 1143409..1144149 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1110; SpoU rRNA methylase family protein 1144149 2861930 SAS1071 Staphylococcus aureus subsp. aureus MSSA476 SpoU rRNA methylase family protein YP_043196.1 1143409 D 282459 CDS YP_043197.1 49485976 2861931 1144530..1145588 1 NC_002953.3 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1145588 pheS 2861931 pheS Staphylococcus aureus subsp. aureus MSSA476 phenylalanyl-tRNA synthetase subunit alpha YP_043197.1 1144530 D 282459 CDS YP_043198.1 49485977 2861927 1145588..1147990 1 NC_002953.3 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1147990 pheT 2861927 pheT Staphylococcus aureus subsp. aureus MSSA476 phenylalanyl-tRNA synthetase subunit beta YP_043198.1 1145588 D 282459 CDS YP_043199.1 49485978 2861913 complement(1148225..1149163) 1 NC_002953.3 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 1149163 2861913 SAS1074 Staphylococcus aureus subsp. aureus MSSA476 ribonuclease HIII YP_043199.1 1148225 R 282459 CDS YP_043200.1 49485979 2864222 1149533..1149799 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1114; hypothetical protein 1149799 2864222 SAS1075 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043200.1 1149533 D 282459 CDS YP_043201.1 49485980 2864223 1149800..1150321 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1115; hypothetical protein 1150321 2864223 SAS1076 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043201.1 1149800 D 282459 CDS YP_043202.1 49485981 2863955 1150394..1152106 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1116; hypothetical protein 1152106 2863955 SAS1077 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043202.1 1150394 D 282459 CDS YP_043203.1 49485982 2863705 1152116..1154464 1 NC_002953.3 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange; recombination and DNA strand exchange inhibitor protein 1154464 2863705 SAS1078 Staphylococcus aureus subsp. aureus MSSA476 recombination and DNA strand exchange inhibitor protein YP_043203.1 1152116 D 282459 CDS YP_043204.1 49485983 2861987 1154637..1154951 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1118; thioredoxin 1154951 2861987 SAS1079 Staphylococcus aureus subsp. aureus MSSA476 thioredoxin YP_043204.1 1154637 D 282459 CDS YP_043205.1 49485984 2864150 1155275..1157056 1 NC_002953.3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1157056 uvrC 2864150 uvrC Staphylococcus aureus subsp. aureus MSSA476 excinuclease ABC subunit C YP_043205.1 1155275 D 282459 CDS YP_043206.1 49485985 2864151 1157380..1157994 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1120; succinate dehydrogenase cytochrome b558 1157994 2864151 SAS1081 Staphylococcus aureus subsp. aureus MSSA476 succinate dehydrogenase cytochrome b558 YP_043206.1 1157380 D 282459 CDS YP_043207.1 49485986 2864152 1158046..1159812 1 NC_002953.3 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 1159812 sdhA 2864152 sdhA Staphylococcus aureus subsp. aureus MSSA476 succinate dehydrogenase flavoprotein subunit YP_043207.1 1158046 D 282459 CDS YP_043208.1 49485987 2864083 1159812..1160627 1 NC_002953.3 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 1160627 sdhB 2864083 sdhB Staphylococcus aureus subsp. aureus MSSA476 succinate dehydrogenase iron-sulfur subunit YP_043208.1 1159812 D 282459 CDS YP_043209.1 49485988 2861877 1160863..1161663 1 NC_002953.3 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1161663 2861877 SAS1084 Staphylococcus aureus subsp. aureus MSSA476 glutamate racemase YP_043209.1 1160863 D 282459 CDS YP_043210.1 49485989 2863036 1161675..1162262 1 NC_002953.3 hydrolyzes non-standard nucleotides such as xanthine and inosine; nucleoside-triphosphatase 1162262 2863036 SAS1085 Staphylococcus aureus subsp. aureus MSSA476 nucleoside-triphosphatase YP_043210.1 1161675 D 282459 CDS YP_043211.1 49485990 2863037 1162255..1162758 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1125; hypothetical protein 1162758 2863037 SAS1086 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043211.1 1162255 D 282459 CDS YP_043212.1 49485991 2863038 1162886..1163053 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1126; hypothetical protein 1163053 2863038 SAS1087 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043212.1 1162886 D 282459 CDS YP_043213.1 49485992 2862639 1163247..1163564 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1127; hypothetical protein 1163564 2862639 SAS1088 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043213.1 1163247 D 282459 CDS YP_043214.1 49485993 2863649 complement(1163934..1164332) 1 NC_002953.3 FLIPr; secreted protein that blocks the formyl peptide receptor-like 1 (FPRL1) found in neutrophils, monocytes, B cells, and NK cells; inhibits the binding of chemoattractants (such as formylated peptides) to FPRL1, which initiates the phagocyte mobilization towards the infection site; formyl peptide receptor-like 1 inhibitory protein 1164332 2863649 SAS1089 Staphylococcus aureus subsp. aureus MSSA476 formyl peptide receptor-like 1 inhibitory protein YP_043214.1 1163934 R 282459 CDS YP_043215.1 49485994 2863452 1165003..1165509 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1129; hypothetical protein 1165509 2863452 SAS1090 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043215.1 1165003 D 282459 CDS YP_043216.1 49485995 2863453 1165768..1166265 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1130; fibrinogen-binding protein precursor 1166265 2863453 SAS1091 Staphylococcus aureus subsp. aureus MSSA476 fibrinogen-binding protein precursor YP_043216.1 1165768 D 282459 CDS YP_043217.1 49485996 2863454 1166419..1166769 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1131; hypothetical protein 1166769 2863454 SAS1092 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043217.1 1166419 D 282459 CDS YP_043218.1 49485997 2864029 1167086..1167409 1 NC_002953.3 hypothetical protein 1167409 2864029 SAS1093 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043218.1 1167086 D 282459 CDS YP_043219.1 49485998 2863298 complement(1167534..1167719) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1133; hypothetical protein 1167719 2863298 SAS1094 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043219.1 1167534 R 282459 CDS YP_043220.1 49485999 2861782 complement(1167926..1168174) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1133a; Poor database matches. Weakly similar to Staphylococcus aureus an internal region of AgrB protein SWALL:Q53644 (EMBL:X52543) (423 aa) fasta scores: E(): 2.2, 30% id in 70 aa. Possible gene remnant; hypothetical protein 1168174 2861782 SAS1095 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043220.1 1167926 R 282459 CDS YP_043221.1 49486000 2861783 complement(1168338..1168571) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1134; hypothetical protein 1168571 2861783 SAS1096 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043221.1 1168338 R 282459 CDS YP_043222.1 49486001 2861784 complement(1169048..1170007) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1136; alpha-hemolysin precursor 1170007 2861784 SAS1097 Staphylococcus aureus subsp. aureus MSSA476 alpha-hemolysin precursor YP_043222.1 1169048 R 282459 CDS YP_043223.1 49486002 2862928 1170680..1170826 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1136a; Doubtful CDS. No database matches; hypothetical protein 1170826 2862928 SAS1097a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043223.1 1170680 D 282459 CDS YP_043224.1 49486003 2863007 1170810..1171007 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1137; hypothetical protein 1171007 2863007 SAS1098 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043224.1 1170810 D 282459 CDS YP_043225.1 49486004 2863567 complement(1171451..1172167) 1 NC_002953.3 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 1172167 2863567 SAS1099 Staphylococcus aureus subsp. aureus MSSA476 superantigen-like protein YP_043225.1 1171451 R 282459 CDS YP_043226.1 49486005 2863568 complement(1172275..1173000) 1 NC_002953.3 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 1173000 2863568 SAS1100 Staphylococcus aureus subsp. aureus MSSA476 superantigen-like protein YP_043226.1 1172275 R 282459 CDS YP_043227.1 49486006 2863569 complement(1173095..1173820) 1 NC_002953.3 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation; superantigen-like protein 1173820 2863569 SAS1101 Staphylococcus aureus subsp. aureus MSSA476 superantigen-like protein YP_043227.1 1173095 R 282459 CDS YP_043228.1 49486007 2863211 1174258..1175259 1 NC_002953.3 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 1175259 2863211 SAS1102 Staphylococcus aureus subsp. aureus MSSA476 ornithine carbamoyltransferase YP_043228.1 1174258 D 282459 CDS YP_043229.1 49486008 2862444 1175282..1176214 1 NC_002953.3 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 1176214 2862444 SAS1103 Staphylococcus aureus subsp. aureus MSSA476 carbamate kinase YP_043229.1 1175282 D 282459 CDS YP_043230.1 49486009 2862061 1176386..1177942 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1144; hypothetical protein 1177942 2862061 SAS1104 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043230.1 1176386 D 282459 CDS YP_043231.1 49486010 2862062 1178249..1178476 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1146; hypothetical protein 1178476 2862062 SAS1105 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043231.1 1178249 D 282459 CDS YP_043232.1 49486011 2862063 complement(1178782..1179729) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1147; hypothetical protein 1179729 2862063 SAS1106 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043232.1 1178782 R 282459 CDS YP_043233.1 49486012 2864248 1179978..1180166 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1148; DNA-binding protein 1180166 2864248 SAS1107 Staphylococcus aureus subsp. aureus MSSA476 DNA-binding protein YP_043233.1 1179978 D 282459 CDS YP_043234.1 49486013 2861845 1181078..1181212 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1150; anti protein 1181212 2861845 SAS1107a Staphylococcus aureus subsp. aureus MSSA476 anti protein YP_043234.1 1181078 D 282459 CDS YP_043235.1 49486014 2863776 1181269..1181403 1 NC_002953.3 anti protein 1181403 2863776 SAS1108 Staphylococcus aureus subsp. aureus MSSA476 anti protein YP_043235.1 1181269 D 282459 CDS YP_043236.1 49486015 2863777 1181536..1182222 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1151; haloacid dehalogenase 1182222 2863777 SAS1109 Staphylococcus aureus subsp. aureus MSSA476 haloacid dehalogenase YP_043236.1 1181536 D 282459 CDS YP_043237.1 49486016 2863778 complement(1182331..1182771) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1152; hypothetical protein 1182771 2863778 SAS1110 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043237.1 1182331 R 282459 CDS YP_043238.1 49486017 2863957 1182966..1184579 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1153; hypothetical protein 1184579 2863957 SAS1111 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043238.1 1182966 D 282459 CDS YP_043239.1 49486018 2863764 1184723..1185154 1 NC_002953.3 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 1185154 2863764 SAS1112 Staphylococcus aureus subsp. aureus MSSA476 cell division protein MraZ YP_043239.1 1184723 D 282459 CDS YP_043240.1 49486019 2863725 1185170..1186105 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1155; S-adenosyl-methyltransferase MraW 1186105 mraW 2863725 mraW Staphylococcus aureus subsp. aureus MSSA476 S-adenosyl-methyltransferase MraW YP_043240.1 1185170 D 282459 CDS YP_043241.1 49486020 2863726 1186119..1186520 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1156; cell division protein 1186520 2863726 SAS1114 Staphylococcus aureus subsp. aureus MSSA476 cell division protein YP_043241.1 1186119 D 282459 CDS YP_043242.1 49486021 2863727 1186501..1188735 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1157; penicillin-binding protein 1 1188735 2863727 SAS1115 Staphylococcus aureus subsp. aureus MSSA476 penicillin-binding protein 1 YP_043242.1 1186501 D 282459 CDS YP_043243.1 49486022 2864233 1189027..1189992 1 NC_002953.3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1189992 mraY 2864233 mraY Staphylococcus aureus subsp. aureus MSSA476 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_043243.1 1189027 D 282459 CDS YP_043244.1 49486023 2862217 1189994..1191343 1 NC_002953.3 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 1191343 murD 2862217 murD Staphylococcus aureus subsp. aureus MSSA476 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_043244.1 1189994 D 282459 CDS YP_043245.1 49486024 2862090 1191356..1192678 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1160; cell division protein 1192678 2862090 SAS1118 Staphylococcus aureus subsp. aureus MSSA476 cell division protein YP_043245.1 1191356 D 282459 CDS YP_043246.1 49486025 2862091 1192784..1194196 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1161; cell division protein 1194196 2862091 SAS1119 Staphylococcus aureus subsp. aureus MSSA476 cell division protein YP_043246.1 1192784 D 282459 CDS YP_043247.1 49486026 2862092 1194229..1195401 1 NC_002953.3 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1195401 2862092 SAS1120 Staphylococcus aureus subsp. aureus MSSA476 cell division protein FtsZ YP_043247.1 1194229 D 282459 CDS YP_043248.1 49486027 2862151 1195661..1196452 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1163; hypothetical protein 1196452 2862151 SAS1121 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043248.1 1195661 D 282459 CDS YP_043249.1 49486028 2863119 1196470..1197144 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1164; hypothetical protein 1197144 2863119 SAS1122 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043249.1 1196470 D 282459 CDS YP_043250.1 49486029 2863870 1197141..1197704 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1165; hypothetical protein 1197704 2863870 SAS1123 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043250.1 1197141 D 282459 CDS YP_043251.1 49486030 2861859 1197716..1198006 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1166; hypothetical protein 1198006 2861859 SAS1124 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043251.1 1197716 D 282459 CDS YP_043252.1 49486031 2861860 1198089..1198895 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1167; hypothetical protein 1198895 2861860 SAS1125 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043252.1 1198089 D 282459 CDS YP_043253.1 49486032 2861835 1198919..1199536 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1168; hypothetical protein 1199536 2861835 SAS1126 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043253.1 1198919 D 282459 CDS YP_043254.1 49486033 2862471 1199757..1202510 1 NC_002953.3 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 1202510 ileS 2862471 ileS Staphylococcus aureus subsp. aureus MSSA476 isoleucyl-tRNA synthetase YP_043254.1 1199757 D 282459 CDS YP_043255.1 49486034 2863138 1202800..1203597 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1171; glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein 1203597 2863138 SAS1128 Staphylococcus aureus subsp. aureus MSSA476 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein YP_043255.1 1202800 D 282459 CDS YP_043256.1 49486035 2863140 1204450..1204941 1 NC_002953.3 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1204941 lspA 2863140 lspA Staphylococcus aureus subsp. aureus MSSA476 lipoprotein signal peptidase YP_043256.1 1204450 D 282459 CDS YP_043257.1 49486036 2862897 1204941..1205858 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1173; RNA pseudouridylate synthase 1205858 2862897 SAS1131 Staphylococcus aureus subsp. aureus MSSA476 RNA pseudouridylate synthase YP_043257.1 1204941 D 282459 CDS YP_043258.1 49486037 2862851 1206258..1206785 1 NC_002953.3 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 1206785 2862851 SAS1132 Staphylococcus aureus subsp. aureus MSSA476 bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase YP_043258.1 1206258 D 282459 CDS YP_043259.1 49486038 2863548 1207003..1208310 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1175; uracil permease 1208310 2863548 SAS1133 Staphylococcus aureus subsp. aureus MSSA476 uracil permease YP_043259.1 1207003 D 282459 CDS YP_043260.1 49486039 2863549 1208338..1209219 1 NC_002953.3 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 1209219 pyrB 2863549 pyrB Staphylococcus aureus subsp. aureus MSSA476 aspartate carbamoyltransferase YP_043260.1 1208338 D 282459 CDS YP_043261.1 49486040 2863550 1209237..1210511 1 NC_002953.3 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1210511 pyrC 2863550 pyrC Staphylococcus aureus subsp. aureus MSSA476 dihydroorotase YP_043261.1 1209237 D 282459 CDS YP_043262.1 49486041 2863559 1210513..1211613 1 NC_002953.3 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1211613 2863559 SAS1136 Staphylococcus aureus subsp. aureus MSSA476 carbamoyl phosphate synthase small subunit YP_043262.1 1210513 D 282459 CDS YP_043263.1 49486042 2862999 1211606..1214779 1 NC_002953.3 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1214779 carB 2862999 carB Staphylococcus aureus subsp. aureus MSSA476 carbamoyl phosphate synthase large subunit YP_043263.1 1211606 D 282459 CDS YP_043264.1 49486043 2861742 1214886..1215581 1 NC_002953.3 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1215581 2861742 SAS1138 Staphylococcus aureus subsp. aureus MSSA476 orotidine 5'-phosphate decarboxylase YP_043264.1 1214886 D 282459 CDS YP_043265.1 49486044 2861743 1215581..1216192 1 NC_002953.3 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1216192 pyrE 2861743 pyrE Staphylococcus aureus subsp. aureus MSSA476 orotate phosphoribosyltransferase YP_043265.1 1215581 D 282459 CDS YP_043266.1 49486045 2861744 1216222..1216434 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1182; hypothetical protein 1216434 2861744 SAS1140 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043266.1 1216222 D 282459 CDS YP_043267.1 49486046 2863517 1216871..1217272 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1183; hypothetical protein 1217272 2863517 SAS1141 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043267.1 1216871 D 282459 CDS YP_043268.1 49486047 2861828 complement(1217535..1219232) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1184; hypothetical protein 1219232 2861828 SAS1142 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043268.1 1217535 R 282459 CDS YP_043269.1 49486048 2861811 1219507..1220130 1 NC_002953.3 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1220130 gmk 2861811 gmk Staphylococcus aureus subsp. aureus MSSA476 guanylate kinase YP_043269.1 1219507 D 282459 CDS YP_043270.1 49486049 2861812 1220130..1220348 1 NC_002953.3 Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 1220348 rpoZ 2861812 rpoZ Staphylococcus aureus subsp. aureus MSSA476 DNA-directed RNA polymerase subunit omega YP_043270.1 1220130 D 282459 CDS YP_043271.1 49486050 2861813 1220564..1221763 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1187; flavoprotein 1221763 2861813 SAS1145 Staphylococcus aureus subsp. aureus MSSA476 flavoprotein YP_043271.1 1220564 D 282459 CDS YP_043272.1 49486051 2864378 1221763..1224171 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1188; primosomal protein n' 1224171 2864378 SAS1146 Staphylococcus aureus subsp. aureus MSSA476 primosomal protein n' YP_043272.1 1221763 D 282459 CDS YP_043273.1 49486052 2861786 1224674..1225627 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1189; lipoprotein 1225627 2861786 SAS1147 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_043273.1 1224674 D 282459 CDS YP_043274.1 49486053 2862693 complement(1225790..1226068) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1190; hypothetical protein 1226068 2862693 SAS1148 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043274.1 1225790 R 282459 CDS YP_043275.1 49486054 2862694 1226292..1226780 1 NC_002953.3 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1226780 2862694 SAS1149 Staphylococcus aureus subsp. aureus MSSA476 peptide deformylase YP_043275.1 1226292 D 282459 CDS YP_043276.1 49486055 2862695 1226773..1227708 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1192; methionyl-tRNA formyltransferase 1227708 2862695 SAS1150 Staphylococcus aureus subsp. aureus MSSA476 methionyl-tRNA formyltransferase YP_043276.1 1226773 D 282459 CDS YP_043277.1 49486056 2863271 1227705..1229012 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1193; hypothetical protein 1229012 2863271 SAS1151 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043277.1 1227705 D 282459 CDS YP_043278.1 49486057 2863339 1229015..1230109 1 NC_002953.3 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 1230109 2863339 SAS1152 Staphylococcus aureus subsp. aureus MSSA476 ribosomal RNA large subunit methyltransferase N YP_043278.1 1229015 D 282459 CDS YP_043279.1 49486058 2864426 1230116..1230859 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1195; protein phosphatase 1230859 2864426 SAS1153 Staphylococcus aureus subsp. aureus MSSA476 protein phosphatase YP_043279.1 1230116 D 282459 CDS YP_043280.1 49486059 2864427 1230856..1232850 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1196; serine/threonine-protein kinase 1232850 2864427 SAS1154 Staphylococcus aureus subsp. aureus MSSA476 serine/threonine-protein kinase YP_043280.1 1230856 D 282459 CDS YP_043281.1 49486060 2864428 1233078..1233953 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1197; hypothetical protein 1233953 2864428 SAS1155 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043281.1 1233078 D 282459 CDS YP_043282.1 49486061 2863342 1233954..1234598 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1198; ribulose-phosphate 3-epimerase 1234598 2863342 SAS1156 Staphylococcus aureus subsp. aureus MSSA476 ribulose-phosphate 3-epimerase YP_043282.1 1233954 D 282459 CDS YP_043283.1 49486062 2863666 1234605..1235246 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1199; hypothetical protein 1235246 2863666 SAS1157 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043283.1 1234605 D 282459 CDS YP_043284.1 49486063 2863359 complement(1235627..1235815) 1 NC_002953.3 required for 70S ribosome assembly; 50S ribosomal protein L28 1235815 rpmB 2863359 rpmB Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L28 YP_043284.1 1235627 R 282459 CDS YP_043285.1 49486064 2863360 1236258..1236632 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1201; hypothetical protein 1236632 2863360 SAS1159 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043285.1 1236258 D 282459 CDS YP_043286.1 49486065 2863361 1236647..1238293 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1202; hypothetical protein 1238293 2863361 SAS1160 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043286.1 1236647 D 282459 CDS YP_043287.1 49486066 2863470 1238483..1240543 1 NC_002953.3 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1240543 2863470 SAS1161 Staphylococcus aureus subsp. aureus MSSA476 ATP-dependent DNA helicase RecG YP_043287.1 1238483 D 282459 CDS YP_043288.1 49486067 2863035 1240761..1241318 1 NC_002953.3 negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria; fatty acid biosynthesis transcriptional regulator 1241318 2863035 SAS1162 Staphylococcus aureus subsp. aureus MSSA476 fatty acid biosynthesis transcriptional regulator YP_043288.1 1240761 D 282459 CDS YP_043289.1 49486068 2863667 1241323..1242309 1 NC_002953.3 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1242309 2863667 SAS1163 Staphylococcus aureus subsp. aureus MSSA476 glycerol-3-phosphate acyltransferase PlsX YP_043289.1 1241323 D 282459 CDS YP_043290.1 49486069 2863668 1242302..1243228 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1206; malonyl CoA-acyl carrier protein transacylase 1243228 2863668 SAS1164 Staphylococcus aureus subsp. aureus MSSA476 malonyl CoA-acyl carrier protein transacylase YP_043290.1 1242302 D 282459 CDS YP_043291.1 49486070 2863669 1243215..1243955 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1207; 3-oxoacyl-ACP reductase 1243955 2863669 SAS1165 Staphylococcus aureus subsp. aureus MSSA476 3-oxoacyl-ACP reductase YP_043291.1 1243215 D 282459 CDS YP_043292.1 49486071 2864060 1244325..1244558 1 NC_002953.3 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1244558 acpP 2864060 acpP Staphylococcus aureus subsp. aureus MSSA476 acyl carrier protein YP_043292.1 1244325 D 282459 CDS YP_043293.1 49486072 2862250 1244674..1245405 1 NC_002953.3 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1245405 rnc 2862250 rnc Staphylococcus aureus subsp. aureus MSSA476 ribonuclease III YP_043293.1 1244674 D 282459 CDS YP_043294.1 49486073 2864344 1245552..1249118 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1210; chromosome partition protein 1249118 2864344 SAS1168 Staphylococcus aureus subsp. aureus MSSA476 chromosome partition protein YP_043294.1 1245552 D 282459 CDS YP_043295.1 49486074 2864345 1249118..1250368 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1211; cell division protein 1250368 2864345 SAS1169 Staphylococcus aureus subsp. aureus MSSA476 cell division protein YP_043295.1 1249118 D 282459 CDS YP_043296.1 49486075 2864346 1250355..1250687 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1212; DNA-binding protein 1250687 2864346 SAS1170 Staphylococcus aureus subsp. aureus MSSA476 DNA-binding protein YP_043296.1 1250355 D 282459 CDS YP_043297.1 49486076 2863104 1250713..1252080 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1213; signal recognition particle protein 1252080 2863104 SAS1171 Staphylococcus aureus subsp. aureus MSSA476 signal recognition particle protein YP_043297.1 1250713 D 282459 CDS YP_043298.1 49486077 2862564 1252515..1252790 1 NC_002953.3 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1252790 rpsP 2862564 rpsP Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S16 YP_043298.1 1252515 D 282459 CDS YP_043299.1 49486078 2864136 1252978..1253481 1 NC_002953.3 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1253481 rimM 2864136 rimM Staphylococcus aureus subsp. aureus MSSA476 16S rRNA-processing protein RimM YP_043299.1 1252978 D 282459 CDS YP_043300.1 49486079 2864137 1253481..1254218 1 NC_002953.3 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1254218 trmD 2864137 trmD Staphylococcus aureus subsp. aureus MSSA476 tRNA (guanine-N(1)-)-methyltransferase YP_043300.1 1253481 D 282459 CDS YP_043301.1 49486080 2864138 1254321..1254671 1 NC_002953.3 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1254671 rplS 2864138 rplS Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L19 YP_043301.1 1254321 D 282459 CDS YP_043302.1 49486081 2861948 complement(1255140..1257746) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1218; hypothetical protein 1257746 2861948 SAS1176 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043302.1 1255140 R 282459 CDS YP_043303.1 49486082 2864198 1258147..1259031 1 NC_002953.3 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase 1259031 rbgA 2864198 rbgA Staphylococcus aureus subsp. aureus MSSA476 ribosomal biogenesis GTPase YP_043303.1 1258147 D 282459 CDS YP_043304.1 49486083 2862530 1259015..1259782 1 NC_002953.3 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1259782 rnhB 2862530 rnhB Staphylococcus aureus subsp. aureus MSSA476 ribonuclease HII YP_043304.1 1259015 D 282459 CDS YP_043305.1 49486084 2862531 1259891..1261057 1 NC_002953.3 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1261057 sucC 2862531 sucC Staphylococcus aureus subsp. aureus MSSA476 succinyl-CoA synthetase subunit beta YP_043305.1 1259891 D 282459 CDS YP_043306.1 49486085 2862532 1261079..1261987 1 NC_002953.3 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 1261987 2862532 SAS1180 Staphylococcus aureus subsp. aureus MSSA476 succinyl-CoA synthetase subunit alpha YP_043306.1 1261079 D 282459 CDS YP_043307.1 49486086 2862516 1262214..1263332 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1223; cell wall hydrolase 1263332 2862516 SAS1181 Staphylococcus aureus subsp. aureus MSSA476 cell wall hydrolase YP_043307.1 1262214 D 282459 CDS YP_043308.1 49486087 2863611 1263360..1264604 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1224; FemAB family protein 1264604 2863611 SAS1182 Staphylococcus aureus subsp. aureus MSSA476 FemAB family protein YP_043308.1 1263360 D 282459 CDS YP_043309.1 49486088 2862412 1264777..1265649 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1225; SMF family protein 1265649 2862412 SAS1183 Staphylococcus aureus subsp. aureus MSSA476 SMF family protein YP_043309.1 1264777 D 282459 CDS YP_043310.1 49486089 2862413 1265829..1267898 1 NC_002953.3 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1267898 2862413 SAS1184 Staphylococcus aureus subsp. aureus MSSA476 DNA topoisomerase I YP_043310.1 1265829 D 282459 CDS YP_043311.1 49486090 2863329 1268054..1269361 1 NC_002953.3 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 1269361 2863329 SAS1185 Staphylococcus aureus subsp. aureus MSSA476 tRNA (uracil-5-)-methyltransferase Gid YP_043311.1 1268054 D 282459 CDS YP_043312.1 49486091 2863404 1269778..1270674 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1228; integrase/recombinase 1270674 2863404 SAS1186 Staphylococcus aureus subsp. aureus MSSA476 integrase/recombinase YP_043312.1 1269778 D 282459 CDS YP_043313.1 49486092 2862909 1270671..1271216 1 NC_002953.3 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 1271216 2862909 SAS1187 Staphylococcus aureus subsp. aureus MSSA476 ATP-dependent protease peptidase subunit YP_043313.1 1270671 D 282459 CDS YP_043314.1 49486093 2862300 1271282..1272685 1 NC_002953.3 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 1272685 hslU 2862300 hslU Staphylococcus aureus subsp. aureus MSSA476 ATP-dependent protease ATP-binding subunit HslU YP_043314.1 1271282 D 282459 CDS YP_043315.1 49486094 2862301 1272710..1273483 1 NC_002953.3 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY 1273483 2862301 SAS1189 Staphylococcus aureus subsp. aureus MSSA476 transcriptional repressor CodY YP_043315.1 1272710 D 282459 CDS YP_043316.1 49486095 2862302 1273825..1274592 1 NC_002953.3 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1274592 rpsB 2862302 rpsB Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S2 YP_043316.1 1273825 D 282459 CDS YP_043317.1 49486096 2861932 1274774..1275655 1 NC_002953.3 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1275655 tsf 2861932 tsf Staphylococcus aureus subsp. aureus MSSA476 elongation factor Ts YP_043317.1 1274774 D 282459 CDS YP_043318.1 49486097 2863415 1275792..1276514 1 NC_002953.3 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1276514 pyrH 2863415 pyrH Staphylococcus aureus subsp. aureus MSSA476 uridylate kinase YP_043318.1 1275792 D 282459 CDS YP_043319.1 49486098 2863416 1276533..1277087 1 NC_002953.3 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1277087 frr 2863416 frr Staphylococcus aureus subsp. aureus MSSA476 ribosome recycling factor YP_043319.1 1276533 D 282459 CDS YP_043320.1 49486099 2862742 1277460..1278230 1 NC_002953.3 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 1278230 2862742 SAS1194 Staphylococcus aureus subsp. aureus MSSA476 undecaprenyl pyrophosphate synthase YP_043320.1 1277460 D 282459 CDS YP_043321.1 49486100 2862279 1278237..1279019 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1237; phosphatidate cytidylyltransferase 1279019 2862279 SAS1195 Staphylococcus aureus subsp. aureus MSSA476 phosphatidate cytidylyltransferase YP_043321.1 1278237 D 282459 CDS YP_043322.1 49486101 2862280 1279231..1280517 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1238; hypothetical protein 1280517 2862280 SAS1196 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043322.1 1279231 D 282459 CDS YP_043323.1 49486102 2862281 1280537..1282240 1 NC_002953.3 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 1282240 2862281 SAS1197 Staphylococcus aureus subsp. aureus MSSA476 prolyl-tRNA synthetase YP_043323.1 1280537 D 282459 CDS YP_043324.1 49486103 2862615 1282498..1286814 1 NC_002953.3 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 1286814 polC 2862615 polC Staphylococcus aureus subsp. aureus MSSA476 DNA polymerase III PolC YP_043324.1 1282498 D 282459 CDS YP_043325.1 49486104 2862964 1287104..1287571 1 NC_002953.3 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 1287571 2862964 SAS1199 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043325.1 1287104 D 282459 CDS YP_043326.1 49486105 2862965 1287592..1288767 1 NC_002953.3 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1288767 nusA 2862965 nusA Staphylococcus aureus subsp. aureus MSSA476 transcription elongation factor NusA YP_043326.1 1287592 D 282459 CDS YP_043327.1 49486106 2862405 1288788..1289072 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1243; hypothetical protein 1289072 2862405 SAS1201 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043327.1 1288788 D 282459 CDS YP_043328.1 49486107 2862517 1289069..1289386 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1244; ribosomal protein 1289386 2862517 SAS1202 Staphylococcus aureus subsp. aureus MSSA476 ribosomal protein YP_043328.1 1289069 D 282459 CDS YP_043329.1 49486108 2862518 1289391..1291508 1 NC_002953.3 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1291508 infB 2862518 infB Staphylococcus aureus subsp. aureus MSSA476 translation initiation factor IF-2 YP_043329.1 1289391 D 282459 CDS YP_043330.1 49486109 2862519 1291894..1292244 1 NC_002953.3 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1292244 rbfA 2862519 rbfA Staphylococcus aureus subsp. aureus MSSA476 ribosome-binding factor A YP_043330.1 1291894 D 282459 CDS YP_043331.1 49486110 2863692 1292414..1293331 1 NC_002953.3 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1293331 2863692 SAS1205 Staphylococcus aureus subsp. aureus MSSA476 tRNA pseudouridine synthase B YP_043331.1 1292414 D 282459 CDS YP_043332.1 49486111 2863749 1293346..1294317 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1248; riboflavin biosynthesis protein 1294317 2863749 SAS1206 Staphylococcus aureus subsp. aureus MSSA476 riboflavin biosynthesis protein YP_043332.1 1293346 D 282459 CDS YP_043333.1 49486112 2863750 1294432..1294701 1 NC_002953.3 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1294701 rpsO 2863750 rpsO Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S15 YP_043333.1 1294432 D 282459 CDS YP_043334.1 49486113 2863765 1295069..1297165 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1250; polynucleotide phosphorylase 1297165 2863765 SAS1208 Staphylococcus aureus subsp. aureus MSSA476 polynucleotide phosphorylase YP_043334.1 1295069 D 282459 CDS YP_043335.1 49486114 2863930 1297401..1299074 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1251; hypothetical protein 1299074 2863930 SAS1209 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043335.1 1297401 D 282459 CDS YP_043336.1 49486115 2863931 1299331..1301700 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1252; DNA translocase (FtsK/SpoIIIE family protein) 1301700 2863931 SAS1210 Staphylococcus aureus subsp. aureus MSSA476 DNA translocase (FtsK/SpoIIIE family protein) YP_043336.1 1299331 D 282459 CDS YP_043337.1 49486116 2863932 1301705..1302418 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1253; hypothetical protein 1302418 2863932 SAS1211 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043337.1 1301705 D 282459 CDS YP_043338.1 49486117 2863730 1302449..1303714 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1254; hypothetical protein 1303714 2863730 SAS1212 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043338.1 1302449 D 282459 CDS YP_043339.1 49486118 2863952 1303714..1305000 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1255; protease 1305000 2863952 SAS1213 Staphylococcus aureus subsp. aureus MSSA476 protease YP_043339.1 1303714 D 282459 CDS YP_043340.1 49486119 2863953 1305000..1305704 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1256; short chain dehydrogenase 1305704 2863953 SAS1214 Staphylococcus aureus subsp. aureus MSSA476 short chain dehydrogenase YP_043340.1 1305000 D 282459 CDS YP_043341.1 49486120 2863919 1305809..1306636 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1257; hypothetical protein 1306636 2863919 SAS1215 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043341.1 1305809 D 282459 CDS YP_043342.1 49486121 2862142 1306655..1307047 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1258; DNA-binding protein 1307047 2862142 SAS1216 Staphylococcus aureus subsp. aureus MSSA476 DNA-binding protein YP_043342.1 1306655 D 282459 CDS YP_043343.1 49486122 2862143 1307081..1307659 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1259; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1307659 2862143 SAS1217 Staphylococcus aureus subsp. aureus MSSA476 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_043343.1 1307081 D 282459 CDS YP_043344.1 49486123 2862144 1307886..1309037 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1260; hypothetical protein 1309037 2862144 SAS1218 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043344.1 1307886 D 282459 CDS YP_043345.1 49486124 2863929 1309202..1310245 1 NC_002953.3 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1310245 recA 2863929 recA Staphylococcus aureus subsp. aureus MSSA476 recombinase A YP_043345.1 1309202 D 282459 CDS YP_043346.1 49486125 2863212 1310599..1312158 1 NC_002953.3 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; phosphodiesterase 1312158 2863212 SAS1220 Staphylococcus aureus subsp. aureus MSSA476 phosphodiesterase YP_043346.1 1310599 D 282459 CDS YP_043347.1 49486126 2863213 complement(1312455..1312670) 1 NC_002953.3 hypothetical protein 1312670 2863213 SAS1221 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043347.1 1312455 R 282459 CDS YP_043348.1 49486127 2862134 1312844..1313641 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1264; hypothetical protein 1313641 2862134 SAS1222 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043348.1 1312844 D 282459 CDS YP_043349.1 49486128 2862213 1313781..1315541 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1265; pyruvate flavodoxin/ferredoxin oxidoreductase 1315541 2862213 SAS1223 Staphylococcus aureus subsp. aureus MSSA476 pyruvate flavodoxin/ferredoxin oxidoreductase YP_043349.1 1313781 D 282459 CDS YP_043350.1 49486129 2862214 1315542..1316408 1 NC_002953.3 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin; 2-oxoglutarate ferredoxin oxidoreductase subunit beta 1316408 2862214 SAS1224 Staphylococcus aureus subsp. aureus MSSA476 2-oxoglutarate ferredoxin oxidoreductase subunit beta YP_043350.1 1315542 D 282459 CDS YP_043351.1 49486130 2861850 1316502..1316795 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1267; hypothetical protein 1316795 2861850 SAS1225 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043351.1 1316502 D 282459 CDS YP_043352.1 49486131 2862445 1316929..1318473 1 NC_002953.3 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1318473 2862445 SAS1226 Staphylococcus aureus subsp. aureus MSSA476 (dimethylallyl)adenosine tRNA methylthiotransferase YP_043352.1 1316929 D 282459 CDS YP_043353.1 49486132 2863829 1318474..1318839 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1269; hypothetical protein 1318839 2863829 SAS1227 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043353.1 1318474 D 282459 CDS YP_043354.1 49486133 2863830 1318866..1319357 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1270; hypothetical protein 1319357 2863830 SAS1228 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043354.1 1318866 D 282459 CDS YP_043355.1 49486134 2862427 1319660..1322278 1 NC_002953.3 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1322278 2862427 SAS1229 Staphylococcus aureus subsp. aureus MSSA476 DNA mismatch repair protein MutS YP_043355.1 1319660 D 282459 CDS YP_043356.1 49486135 2862319 1322291..1324300 1 NC_002953.3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 1324300 mutL 2862319 mutL Staphylococcus aureus subsp. aureus MSSA476 DNA mismatch repair protein YP_043356.1 1322291 D 282459 CDS YP_043357.1 49486136 2862320 1324315..1324848 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1273; glycerol uptake operon antiterminator regulatory protein 1324848 2862320 SAS1231 Staphylococcus aureus subsp. aureus MSSA476 glycerol uptake operon antiterminator regulatory protein YP_043357.1 1324315 D 282459 CDS YP_043358.1 49486137 2862321 complement(1324885..1324983) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1273a; Doubtful CDS. No significant database hits; hypothetical protein 1324983 2862321 SAS1231a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043358.1 1324885 R 282459 CDS YP_043359.1 49486138 2863572 1325323..1326141 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1274; glycerol uptake facilitator protein 1326141 2863572 SAS1232 Staphylococcus aureus subsp. aureus MSSA476 glycerol uptake facilitator protein YP_043359.1 1325323 D 282459 CDS YP_043360.1 49486139 2863532 1326270..1327766 1 NC_002953.3 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 1327766 glpK 2863532 glpK Staphylococcus aureus subsp. aureus MSSA476 glycerol kinase YP_043360.1 1326270 D 282459 CDS YP_043361.1 49486140 2863533 1327876..1329597 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1276; aerobic glycerol-3-phosphate dehydrogenase 1329597 2863533 SAS1234 Staphylococcus aureus subsp. aureus MSSA476 aerobic glycerol-3-phosphate dehydrogenase YP_043361.1 1327876 D 282459 CDS YP_043362.1 49486141 2863820 1329747..1330661 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1277; hydrolase 1330661 2863820 SAS1235 Staphylococcus aureus subsp. aureus MSSA476 hydrolase YP_043362.1 1329747 D 282459 CDS YP_043363.1 49486142 2862119 1330679..1331614 1 NC_002953.3 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1331614 miaA 2862119 miaA Staphylococcus aureus subsp. aureus MSSA476 tRNA delta(2)-isopentenylpyrophosphate transferase YP_043363.1 1330679 D 282459 CDS YP_043364.1 49486143 2862120 1331629..1331862 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1279; hypothetical protein 1331862 2862120 SAS1237 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043364.1 1331629 D 282459 CDS YP_043365.1 49486144 2862121 complement(1332084..1332560) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1280; glutathione peroxidase 1332560 2862121 SAS1238 Staphylococcus aureus subsp. aureus MSSA476 glutathione peroxidase YP_043365.1 1332084 R 282459 CDS YP_043366.1 49486145 2863535 1332672..1333910 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1281; hypothetical protein 1333910 2863535 SAS1239 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043366.1 1332672 D 282459 CDS YP_043367.1 49486146 2862962 1333929..1335167 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1282; hypothetical protein 1335167 2862962 SAS1240 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043367.1 1333929 D 282459 CDS YP_043368.1 49486147 2862963 1335411..1335779 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1283; glutamine synthetase 1335779 2862963 SAS1241 Staphylococcus aureus subsp. aureus MSSA476 glutamine synthetase YP_043368.1 1335411 D 282459 CDS YP_043369.1 49486148 2862959 1335798..1337138 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1284; glutamine synthetase 1337138 2862959 SAS1242 Staphylococcus aureus subsp. aureus MSSA476 glutamine synthetase YP_043369.1 1335798 D 282459 CDS YP_043370.1 49486149 2864042 1337641..1337838 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1285; hypothetical protein 1337838 2864042 SAS1243 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043370.1 1337641 D 282459 CDS YP_043371.1 49486150 2864043 1338539..1338745 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1302; hypothetical protein 1338745 2864043 SAS1244 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043371.1 1338539 D 282459 CDS YP_043372.1 49486151 2864044 1339042..1339248 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1303; hypothetical protein 1339248 2864044 SAS1245 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043372.1 1339042 D 282459 CDS YP_043373.1 49486152 2862757 1341182..1341286 1 NC_002953.3 Doubtful CDS. No database matches; hypothetical protein 1341286 2862757 SAS1246a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043373.1 1341182 D 282459 CDS YP_043374.1 49486153 2862758 1341415..1341666 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1311; hypothetical protein 1341666 2862758 SAS1247 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043374.1 1341415 D 282459 CDS YP_043375.1 49486154 2863334 1342141..1342575 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1314; hypothetical protein 1342575 2863334 SAS1249 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043375.1 1342141 D 282459 CDS YP_043376.1 49486155 2864452 1342863..1343075 1 NC_002953.3 Poor database matches. Weakly similar to the N-terminal region of mycobacteriophage TM4 protein Gp8 SWALL:Q9ZX69 (EMBL:AF068845) (186 aa) fasta scores: E(): 1.9, 37.83% id in 74 aa; hypothetical protein 1343075 2864452 SAS1250 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043376.1 1342863 D 282459 CDS YP_043377.1 49486156 2864453 1343195..1343464 1 NC_002953.3 hypothetical protein 1343464 2864453 SAS1251 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043377.1 1343195 D 282459 CDS YP_043378.1 49486157 2864454 1343477..1343599 1 NC_002953.3 hypothetical protein 1343599 2864454 SAS1252 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043378.1 1343477 D 282459 CDS YP_043379.1 49486158 2863989 1344328..1344522 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1317; hypothetical protein 1344522 2863989 SAS1254 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043379.1 1344328 D 282459 CDS YP_043380.1 49486159 2863990 1344808..1344918 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1325b; Poor database matches. Similar to Bacillus anthracis conserved domain protein BA3762 SWALL:Q81XZ9 (EMBL:AE017035) (40 aa) fasta scores: E(): 1, 39.39% id in 33 aa; hypothetical protein 1344918 2863990 SAS1255 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043380.1 1344808 D 282459 CDS YP_043381.1 49486160 2863350 complement(1345083..1346108) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1326; hypothetical protein 1346108 2863350 SAS1256 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043381.1 1345083 R 282459 CDS YP_043382.1 49486161 2862628 1346378..1346575 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1327; hypothetical protein 1346575 2862628 SAS1257 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043382.1 1346378 D 282459 CDS YP_043383.1 49486162 2862629 1346632..1348113 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1328; cardiolipin synthase 1348113 2862629 SAS1258 Staphylococcus aureus subsp. aureus MSSA476 cardiolipin synthase YP_043383.1 1346632 D 282459 CDS YP_043384.1 49486163 2862630 1348288..1349196 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1329; ABC transporter ATP-binding protein 1349196 2862630 SAS1259 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_043384.1 1348288 D 282459 CDS YP_043385.1 49486164 2862638 1349165..1349896 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1330; hypothetical protein 1349896 2862638 SAS1260 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043385.1 1349165 D 282459 CDS YP_043386.1 49486165 2862684 1349900..1350991 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1331; sensor kinase 1350991 2862684 SAS1261 Staphylococcus aureus subsp. aureus MSSA476 sensor kinase YP_043386.1 1349900 D 282459 CDS YP_043387.1 49486166 2862685 1350988..1351590 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1332; response regulator 1351590 2862685 SAS1262 Staphylococcus aureus subsp. aureus MSSA476 response regulator YP_043387.1 1350988 D 282459 CDS YP_043388.1 49486167 2862662 complement(1351703..1351891) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1333; hypothetical protein 1351891 2862662 SAS1263 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043388.1 1351703 R 282459 CDS YP_043389.1 49486168 2862652 1352030..1352563 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1334; thermonuclease 1352563 2862652 SAS1264 Staphylococcus aureus subsp. aureus MSSA476 thermonuclease YP_043389.1 1352030 D 282459 CDS YP_043390.1 49486169 2862653 complement(1352706..1353560) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1335; hypothetical protein 1353560 2862653 SAS1265 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043390.1 1352706 R 282459 CDS YP_043391.1 49486170 2862654 1353876..1354466 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1336; hypothetical protein 1354466 2862654 SAS1266 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043391.1 1353876 D 282459 CDS YP_043392.1 49486171 2863449 complement(1354520..1355914) 1 NC_002953.3 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase 1355914 2863449 SAS1267 Staphylococcus aureus subsp. aureus MSSA476 aspartate kinase YP_043392.1 1354520 R 282459 CDS YP_043393.1 49486172 2863441 1356093..1357373 1 NC_002953.3 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1357373 2863441 SAS1268 Staphylococcus aureus subsp. aureus MSSA476 homoserine dehydrogenase YP_043393.1 1356093 D 282459 CDS YP_043394.1 49486173 2863442 1357379..1358440 1 NC_002953.3 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 1358440 2863442 SAS1269 Staphylococcus aureus subsp. aureus MSSA476 threonine synthase YP_043394.1 1357379 D 282459 CDS YP_043395.1 49486174 2863487 1358442..1359356 1 NC_002953.3 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 1359356 2863487 SAS1270 Staphylococcus aureus subsp. aureus MSSA476 homoserine kinase YP_043395.1 1358442 D 282459 CDS YP_043396.1 49486175 2864065 1359414..1360217 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1341; haloacid dehalogenase 1360217 2864065 SAS1271 Staphylococcus aureus subsp. aureus MSSA476 haloacid dehalogenase YP_043396.1 1359414 D 282459 CDS YP_043397.1 49486176 2864066 complement(1360510..1360824) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1342; hypothetical protein 1360824 2864066 SAS1272 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043397.1 1360510 R 282459 CDS YP_043398.1 49486177 2864067 complement(1361042..1362496) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1343; amino acid permease 1362496 2864067 SAS1273 Staphylococcus aureus subsp. aureus MSSA476 amino acid permease YP_043398.1 1361042 R 282459 CDS YP_043399.1 49486178 2861874 1362700..1364217 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1344; catalase 1364217 2861874 SAS1274 Staphylococcus aureus subsp. aureus MSSA476 catalase YP_043399.1 1362700 D 282459 CDS YP_043400.1 49486179 2863661 1364308..1364457 1 NC_002953.3 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1364457 rpmG 2863661 rpmG Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L33 YP_043400.1 1364308 D 282459 CDS YP_043401.1 49486180 2863662 1364911..1365180 1 NC_002953.3 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 1365180 rpsN 2863662 rpsN Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S14 YP_043401.1 1364911 D 282459 CDS YP_043402.1 49486181 2864061 1365337..1366314 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1347; guanosine 5'-monophosphate oxidoreductase 1366314 2864061 SAS1277 Staphylococcus aureus subsp. aureus MSSA476 guanosine 5'-monophosphate oxidoreductase YP_043402.1 1365337 D 282459 CDS YP_043403.1 49486182 2864321 1366489..1367352 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1348; hypothetical protein 1367352 2864321 SAS1278 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043403.1 1366489 D 282459 CDS YP_043404.1 49486183 2864322 complement(1367732..1368355) 1 NC_002953.3 Represses a number of genes involved in the response to DNA damage; LexA repressor 1368355 2864322 SAS1279 Staphylococcus aureus subsp. aureus MSSA476 LexA repressor YP_043404.1 1367732 R 282459 CDS YP_043405.1 49486184 2864323 1368495..1368731 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1350; hypothetical protein 1368731 2864323 SAS1280 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043405.1 1368495 D 282459 CDS YP_043406.1 49486185 2864080 1368867..1369106 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1351; hypothetical protein 1369106 2864080 SAS1281 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043406.1 1368867 D 282459 CDS YP_043407.1 49486186 2864103 1369227..1371215 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1352; transketolase 1371215 2864103 SAS1282 Staphylococcus aureus subsp. aureus MSSA476 transketolase YP_043407.1 1369227 D 282459 CDS YP_043408.1 49486187 2864104 1371493..1371735 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1353; hypothetical protein 1371735 2864104 SAS1283 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043408.1 1371493 D 282459 CDS YP_043409.1 49486188 2864094 1371914..1372381 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1355; hypothetical protein 1372381 2864094 SAS1284 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043409.1 1371914 D 282459 CDS YP_043410.1 49486189 2864306 1372505..1373626 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1356; exonuclease 1373626 2864306 SAS1285 Staphylococcus aureus subsp. aureus MSSA476 exonuclease YP_043410.1 1372505 D 282459 CDS YP_043411.1 49486190 2864307 1373630..1376659 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1357; exonuclease 1376659 2864307 SAS1286 Staphylococcus aureus subsp. aureus MSSA476 exonuclease YP_043411.1 1373630 D 282459 CDS YP_043412.1 49486191 2864308 complement(1376730..1377092) 1 NC_002953.3 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 1377092 mscL 2864308 mscL Staphylococcus aureus subsp. aureus MSSA476 large-conductance mechanosensitive channel YP_043412.1 1376730 R 282459 CDS YP_043413.1 49486192 2864302 1377296..1378942 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1361; glycine betaine transporter 1 1378942 2864302 SAS1288 Staphylococcus aureus subsp. aureus MSSA476 glycine betaine transporter 1 YP_043413.1 1377296 D 282459 CDS YP_043414.1 49486193 2862277 1379834..1382539 1 NC_002953.3 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1382539 2862277 SAS1289 Staphylococcus aureus subsp. aureus MSSA476 aconitate hydratase YP_043414.1 1379834 D 282459 CDS YP_043415.1 49486194 2862278 1382719..1383186 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1363; hypothetical protein 1383186 2862278 SAS1290 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043415.1 1382719 D 282459 CDS YP_043416.1 49486195 2862283 complement(1383393..1383689) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1364; hypothetical protein 1383689 2862283 SAS1292 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043416.1 1383393 R 282459 CDS YP_043417.1 49486196 2864208 complement(1384064..1384672) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1365; hypothetical protein 1384672 2864208 SAS1293 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043417.1 1384064 R 282459 CDS YP_043418.1 49486197 2864209 1384872..1386869 1 NC_002953.3 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1386869 2864209 SAS1294 Staphylococcus aureus subsp. aureus MSSA476 DNA topoisomerase IV subunit B YP_043418.1 1384872 D 282459 CDS YP_043419.1 49486198 2864210 1386869..1389271 1 NC_002953.3 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 1389271 2864210 SAS1295 Staphylococcus aureus subsp. aureus MSSA476 DNA topoisomerase IV subunit A YP_043419.1 1386869 D 282459 CDS YP_043420.1 49486199 2861969 1389521..1390981 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1368; sodium:alanine symporter family protein 1390981 2861969 SAS1296 Staphylococcus aureus subsp. aureus MSSA476 sodium:alanine symporter family protein YP_043420.1 1389521 D 282459 CDS YP_043421.1 49486200 2862234 1391481..1392332 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1369; transcription antiterminator 1392332 2862234 SAS1297 Staphylococcus aureus subsp. aureus MSSA476 transcription antiterminator YP_043421.1 1391481 D 282459 CDS YP_043422.1 49486201 2862235 1392379..1392474 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1370; hypothetical protein 1392474 2862235 SAS1298 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043422.1 1392379 D 282459 CDS YP_043423.1 49486202 2862557 1392467..1393675 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1371; hypothetical protein 1393675 2862557 SAS1299 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043423.1 1392467 D 282459 CDS YP_043424.1 49486203 2862588 1394156..1396678 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1372; hypothetical protein 1396678 2862588 SAS1300 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043424.1 1394156 D 282459 CDS YP_043425.1 49486204 2862589 complement(1396881..1397390) 1 NC_002953.3 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 1397390 2862589 SAS1301 Staphylococcus aureus subsp. aureus MSSA476 methionine sulfoxide reductase A YP_043425.1 1396881 R 282459 CDS YP_043426.1 49486205 2862590 1397527..1398510 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1374; hypothetical protein 1398510 2862590 SAS1302 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043426.1 1397527 D 282459 CDS YP_043427.1 49486206 2864157 complement(1398598..1398786) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1376; 4-oxalocrotonate tautomerase 1398786 2864157 SAS1303 Staphylococcus aureus subsp. aureus MSSA476 4-oxalocrotonate tautomerase YP_043427.1 1398598 R 282459 CDS YP_043428.1 49486207 2861988 1398931..1400193 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1377; ImpB/MucB/SamB family protein 1400193 2861988 SAS1304 Staphylococcus aureus subsp. aureus MSSA476 ImpB/MucB/SamB family protein YP_043428.1 1398931 D 282459 CDS YP_043429.1 49486208 2861989 complement(1400329..1401420) 1 NC_002953.3 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 1401420 2861989 SAS1305 Staphylococcus aureus subsp. aureus MSSA476 prephenate dehydrogenase YP_043429.1 1400329 R 282459 CDS YP_043430.1 49486209 2862408 1401585..1402616 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1379; peptidase 1402616 2862408 SAS1306 Staphylococcus aureus subsp. aureus MSSA476 peptidase YP_043430.1 1401585 D 282459 CDS YP_043431.1 49486210 2863872 1403108..1404514 1 NC_002953.3 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1404514 2863872 SAS1307 Staphylococcus aureus subsp. aureus MSSA476 anthranilate synthase component I YP_043431.1 1403108 D 282459 CDS YP_043432.1 49486211 2863873 1404511..1405077 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1381; anthranilate synthase component II 1405077 2863873 SAS1308 Staphylococcus aureus subsp. aureus MSSA476 anthranilate synthase component II YP_043432.1 1404511 D 282459 CDS YP_043433.1 49486212 2863874 1405083..1406081 1 NC_002953.3 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1406081 trpD 2863874 trpD Staphylococcus aureus subsp. aureus MSSA476 anthranilate phosphoribosyltransferase YP_043433.1 1405083 D 282459 CDS YP_043434.1 49486213 2863605 1406083..1406865 1 NC_002953.3 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol phosphate synthase 1406865 trpC 2863605 trpC Staphylococcus aureus subsp. aureus MSSA476 indole-3-glycerol phosphate synthase YP_043434.1 1406083 D 282459 CDS YP_043435.1 49486214 2863799 1406865..1407497 1 NC_002953.3 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase 1407497 2863799 SAS1311 Staphylococcus aureus subsp. aureus MSSA476 N-(5'-phosphoribosyl)anthranilate isomerase YP_043435.1 1406865 D 282459 CDS YP_043436.1 49486215 2863800 1407490..1408704 1 NC_002953.3 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1408704 2863800 SAS1312 Staphylococcus aureus subsp. aureus MSSA476 tryptophan synthase subunit beta YP_043436.1 1407490 D 282459 CDS YP_043437.1 49486216 2862351 1408697..1409425 1 NC_002953.3 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1409425 trpA 2862351 trpA Staphylococcus aureus subsp. aureus MSSA476 tryptophan synthase subunit alpha YP_043437.1 1408697 D 282459 CDS YP_043438.1 49486217 2862354 1409747..1411009 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1387; factor essential for expression of methicillin resistance 1411009 2862354 SAS1314 Staphylococcus aureus subsp. aureus MSSA476 factor essential for expression of methicillin resistance YP_043438.1 1409747 D 282459 CDS YP_043439.1 49486218 2862355 1411028..1412287 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1388; methicillin resistance expression factor 1412287 2862355 SAS1315 Staphylococcus aureus subsp. aureus MSSA476 methicillin resistance expression factor YP_043439.1 1411028 D 282459 CDS YP_043440.1 49486219 2862356 1412576..1413232 1 NC_002953.3 hypothetical protein 1413232 2862356 SAS1316 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043440.1 1412576 D 282459 CDS YP_043441.1 49486220 2862366 complement(1414319..1414792) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1391; hypothetical protein 1414792 2862366 SAS1319 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043441.1 1414319 R 282459 CDS YP_043442.1 49486221 2862367 complement(1414916..1415617) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1392; oligopeptide transporter ATPase 1415617 2862367 SAS1320 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transporter ATPase YP_043442.1 1414916 R 282459 CDS YP_043443.1 49486222 2863497 complement(1415610..1416383) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1393; oligopeptide transporter ATPase 1416383 2863497 SAS1321 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transporter ATPase YP_043443.1 1415610 R 282459 CDS YP_043444.1 49486223 2863498 complement(1416370..1417200) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1394; oligopeptide transport system permease 1417200 2863498 SAS1322 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transport system permease YP_043444.1 1416370 R 282459 CDS YP_043445.1 49486224 2862369 complement(1417193..1418179) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1395; oligopeptide transport system permease 1418179 2862369 SAS1323 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transport system permease YP_043445.1 1417193 R 282459 CDS YP_043446.1 49486225 2862347 complement(1418483..1418827) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1396; hypothetical protein 1418827 2862347 SAS1324 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043446.1 1418483 R 282459 CDS YP_043447.1 49486226 2862348 1419032..1420846 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1397; peptidase 1420846 2862348 SAS1325 Staphylococcus aureus subsp. aureus MSSA476 peptidase YP_043447.1 1419032 D 282459 CDS YP_043448.1 49486227 2862342 complement(1420985..1421626) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1398; phosphate transport system protein 1421626 2862342 SAS1326 Staphylococcus aureus subsp. aureus MSSA476 phosphate transport system protein YP_043448.1 1420985 R 282459 CDS YP_043449.1 49486228 2862343 complement(1421633..1422484) 1 NC_002953.3 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 1422484 2862343 SAS1327 Staphylococcus aureus subsp. aureus MSSA476 phosphate transporter ATP-binding protein YP_043449.1 1421633 R 282459 CDS YP_043450.1 49486229 2862335 complement(1422531..1423448) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1400; ABC transporter permease 1423448 2862335 SAS1328 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter permease YP_043450.1 1422531 R 282459 CDS YP_043451.1 49486230 2862336 complement(1423450..1424376) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1401; ABC transporter permease 1424376 2862336 SAS1329 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter permease YP_043451.1 1423450 R 282459 CDS YP_043452.1 49486231 2861938 complement(1424567..1425550) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1402; phosphate-binding lipoprotein 1425550 2861938 SAS1330 Staphylococcus aureus subsp. aureus MSSA476 phosphate-binding lipoprotein YP_043452.1 1424567 R 282459 CDS YP_043453.1 49486232 2861937 complement(1426526..1427428) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1403; hypothetical protein 1427428 2861937 SAS1332 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043453.1 1426526 R 282459 CDS YP_043454.1 49486233 2861910 1427575..1429176 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1404; ABC transporter ATP-binding protein 1429176 2861910 SAS1333 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_043454.1 1427575 D 282459 CDS YP_043455.1 49486234 2861911 1430043..1431248 1 NC_002953.3 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1431248 2861911 SAS1334 Staphylococcus aureus subsp. aureus MSSA476 aspartate kinase YP_043455.1 1430043 D 282459 CDS YP_043456.1 49486235 2861898 1431312..1432301 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1406; aspartate semialdehyde dehydrogenase 1432301 2861898 SAS1335 Staphylococcus aureus subsp. aureus MSSA476 aspartate semialdehyde dehydrogenase YP_043456.1 1431312 D 282459 CDS YP_043457.1 49486236 2861899 1432303..1433190 1 NC_002953.3 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1433190 dapA 2861899 dapA Staphylococcus aureus subsp. aureus MSSA476 dihydrodipicolinate synthase YP_043457.1 1432303 D 282459 CDS YP_043458.1 49486237 2862298 1433187..1433909 1 NC_002953.3 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1433909 2862298 SAS1337 Staphylococcus aureus subsp. aureus MSSA476 dihydrodipicolinate reductase YP_043458.1 1433187 D 282459 CDS YP_043459.1 49486238 2862299 1433936..1434655 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1409; tetrahydrodipicolinate acetyltransferase 1434655 2862299 SAS1338 Staphylococcus aureus subsp. aureus MSSA476 tetrahydrodipicolinate acetyltransferase YP_043459.1 1433936 D 282459 CDS YP_043460.1 49486239 2863130 1434798..1435949 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1410; peptidase 1435949 2863130 SAS1339 Staphylococcus aureus subsp. aureus MSSA476 peptidase YP_043460.1 1434798 D 282459 CDS YP_043461.1 49486240 2863131 1435954..1437039 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1411; alanine racemase 1437039 2863131 SAS1340 Staphylococcus aureus subsp. aureus MSSA476 alanine racemase YP_043461.1 1435954 D 282459 CDS YP_043462.1 49486241 2862327 1437029..1438294 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1412; diaminopimelate decarboxylase 1438294 2862327 SAS1341 Staphylococcus aureus subsp. aureus MSSA476 diaminopimelate decarboxylase YP_043462.1 1437029 D 282459 CDS YP_043463.1 49486242 2862769 complement(1438534..1438935) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1413; hypothetical protein 1438935 2862769 SAS1342 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043463.1 1438534 R 282459 CDS YP_043464.1 49486243 2862770 complement(1439132..1439332) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1414; cold shock protein 1439332 2862770 SAS1343 Staphylococcus aureus subsp. aureus MSSA476 cold shock protein YP_043464.1 1439132 R 282459 CDS YP_043465.1 49486244 2864050 complement(1439503..1439811) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1415; hypothetical protein 1439811 2864050 SAS1344 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043465.1 1439503 R 282459 CDS YP_043466.1 49486245 2864051 1439974..1440243 1 NC_002953.3 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1440243 2864051 SAS1345 Staphylococcus aureus subsp. aureus MSSA476 acylphosphatase YP_043466.1 1439974 D 282459 CDS YP_043467.1 49486246 2864263 1440268..1440891 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1417; hypothetical protein 1440891 2864263 SAS1346 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043467.1 1440268 D 282459 CDS YP_043468.1 49486247 2864264 1440923..1442059 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1418; hypothetical protein 1442059 2864264 SAS1347 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043468.1 1440923 D 282459 CDS YP_043469.1 49486248 2863772 complement(1443072..1444415) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1419; branched-chain amino acid transporter protein 1444415 2863772 SAS1350 Staphylococcus aureus subsp. aureus MSSA476 branched-chain amino acid transporter protein YP_043469.1 1443072 R 282459 CDS YP_043470.1 49486249 2862838 complement(1444640..1446526) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1420; hypothetical protein 1446526 2862838 SAS1351 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043470.1 1444640 R 282459 CDS YP_043471.1 49486250 2862374 complement(1446540..1447331) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1421; hypothetical protein 1447331 2862374 SAS1352 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043471.1 1446540 R 282459 CDS YP_043472.1 49486251 2862375 complement(1447512..1447715) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1422; hypothetical protein 1447715 2862375 SAS1353 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043472.1 1447512 R 282459 CDS YP_043473.1 49486252 2863923 complement(1447744..1448553) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1423; hypothetical protein 1448553 2863923 SAS1354 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043473.1 1447744 R 282459 CDS YP_043474.1 49486253 2863924 complement(1449133..1450401) 1 NC_002953.3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 1450401 2863924 SAS1355 Staphylococcus aureus subsp. aureus MSSA476 dihydrolipoamide succinyltransferase YP_043474.1 1449133 R 282459 CDS YP_043475.1 49486254 2863894 complement(1450415..1453213) 1 NC_002953.3 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 1453213 sucA 2863894 sucA Staphylococcus aureus subsp. aureus MSSA476 2-oxoglutarate dehydrogenase E1 YP_043475.1 1450415 R 282459 CDS YP_043476.1 49486255 2863895 complement(1453497..1454852) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1426; sensor kinase 1454852 2863895 SAS1357 Staphylococcus aureus subsp. aureus MSSA476 sensor kinase YP_043476.1 1453497 R 282459 CDS YP_043477.1 49486256 2862195 complement(1454849..1455508) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1427; response regulator protein 1455508 2862195 SAS1358 Staphylococcus aureus subsp. aureus MSSA476 response regulator protein YP_043477.1 1454849 R 282459 CDS YP_043478.1 49486257 2862196 complement(1455979..1456152) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1428; Doubtful CDS. No significant database hits; hypothetical protein 1456152 2862196 SAS1358a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043478.1 1455979 R 282459 CDS YP_043479.1 49486258 2863208 complement(1456295..1456909) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1429; hypothetical protein 1456909 2863208 SAS1359 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043479.1 1456295 R 282459 CDS YP_043480.1 49486259 2863214 complement(1456926..1457996) 1 NC_002953.3 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1457996 murG 2863214 murG Staphylococcus aureus subsp. aureus MSSA476 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_043480.1 1456926 R 282459 CDS YP_043481.1 49486260 2863215 complement(1458008..1458517) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1431; acetyltransferase 1458517 2863215 SAS1361 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase YP_043481.1 1458008 R 282459 CDS YP_043482.1 49486261 2862498 complement(1459705..1461195) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1432; protease 1461195 2862498 SAS1363 Staphylococcus aureus subsp. aureus MSSA476 protease YP_043482.1 1459705 R 282459 CDS YP_043483.1 49486262 2863217 complement(1461387..1461608) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1434; hypothetical protein 1461608 2863217 SAS1364 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043483.1 1461387 R 282459 CDS YP_043484.1 49486263 2863218 complement(1461608..1462108) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1435; PTS system glucose-specific transporter subunit IIA 1462108 2863218 SAS1365 Staphylococcus aureus subsp. aureus MSSA476 PTS system glucose-specific transporter subunit IIA YP_043484.1 1461608 R 282459 CDS YP_043485.1 49486264 2862047 complement(1462120..1462548) 1 NC_002953.3 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 1462548 2862047 SAS1366 Staphylococcus aureus subsp. aureus MSSA476 methionine sulfoxide reductase B YP_043485.1 1462120 R 282459 CDS YP_043486.1 49486265 2862048 complement(1462541..1463074) 1 NC_002953.3 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 1463074 2862048 SAS1367 Staphylococcus aureus subsp. aureus MSSA476 methionine sulfoxide reductase A YP_043486.1 1462541 R 282459 CDS YP_043487.1 49486266 2862847 complement(1463160..1463999) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1438; hypothetical protein 1463999 2862847 SAS1368 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043487.1 1463160 R 282459 CDS YP_043488.1 49486267 2862453 complement(1464014..1464493) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1439; dihydrofolate reductase 1464493 2862453 SAS1369 Staphylococcus aureus subsp. aureus MSSA476 dihydrofolate reductase YP_043488.1 1464014 R 282459 CDS YP_043489.1 49486268 2862454 complement(1464693..1465649) 1 NC_002953.3 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1465649 thyA 2862454 thyA Staphylococcus aureus subsp. aureus MSSA476 thymidylate synthase YP_043489.1 1464693 R 282459 CDS YP_043490.1 49486269 2862215 complement(1466073..1466510) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1441; hypothetical protein 1466510 2862215 SAS1371 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043490.1 1466073 R 282459 CDS YP_043491.1 49486270 2862216 complement(1466526..1467650) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1442; hypothetical protein 1467650 2862216 SAS1372 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043491.1 1466526 R 282459 CDS YP_043492.1 49486271 2863848 complement(1467689..1467940) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1443; Similar to the N-terminal region of Bacillus halodurans hypothetical protein BH1718 SWALL:Q9KC56 (EMBL:AP001512) (380 aa) fasta scores: E(): 1.4e-09, 42.16% id in 83 aa. Possible gene remnant; hypothetical protein 1467940 2863848 SAS1373 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043492.1 1467689 R 282459 CDS YP_043493.1 49486272 2863849 complement(1467952..1468146) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1444; hypothetical protein 1468146 2863849 SAS1374 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043493.1 1467952 R 282459 CDS YP_043494.1 49486273 2862459 1468391..1469095 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1445; hypothetical protein 1469095 2862459 SAS1375 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043494.1 1468391 D 282459 CDS YP_043495.1 49486274 2862460 <1469127..1469261 1 NC_002953.3 Doubtful CDS. No database matches; hypothetical protein 1469261 2862460 SAS1375a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043495.1 <1469127 D 282459 CDS YP_043496.1 49486275 2862919 1469635..1470036 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1446; hypothetical protein 1470036 2862919 SAS1376 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043496.1 1469635 D 282459 CDS YP_043497.1 49486276 2862920 complement(1497358..1498749) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1448; transporter protein 1498749 2862920 SAS1379 Staphylococcus aureus subsp. aureus MSSA476 transporter protein YP_043497.1 1497358 R 282459 CDS YP_043498.1 49486277 2862921 complement(1498906..1500228) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1449; amino acid permease 1500228 2862921 SAS1380 Staphylococcus aureus subsp. aureus MSSA476 amino acid permease YP_043498.1 1498906 R 282459 CDS YP_043499.1 49486278 2863853 complement(1500259..1501299) 1 NC_002953.3 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase 1501299 2863853 SAS1381 Staphylococcus aureus subsp. aureus MSSA476 threonine dehydratase YP_043499.1 1500259 R 282459 CDS YP_043500.1 49486279 2863854 complement(1501394..1502512) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1451; alanine dehydrogenase 1502512 2863854 SAS1382 Staphylococcus aureus subsp. aureus MSSA476 alanine dehydrogenase YP_043500.1 1501394 R 282459 CDS YP_043501.1 49486280 2863573 complement(1502988..1503866) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1452; 5'-3' exonuclease 1503866 2863573 SAS1383 Staphylococcus aureus subsp. aureus MSSA476 5'-3' exonuclease YP_043501.1 1502988 R 282459 CDS YP_043502.1 49486281 2863574 complement(1503886..1507326) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1453; hypothetical protein 1507326 2863574 SAS1384 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043502.1 1503886 R 282459 CDS YP_043503.1 49486282 2863236 1507629..1508969 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1454; hypothetical protein 1508969 2863236 SAS1385 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043503.1 1507629 D 282459 CDS YP_043504.1 49486283 2863237 complement(1509540..1509872) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1455; hypothetical protein 1509872 2863237 SAS1386 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043504.1 1509540 R 282459 CDS YP_043505.1 49486284 2862096 complement(1509956..1511101) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1456; hypothetical protein 1511101 2862096 SAS1387 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043505.1 1509956 R 282459 CDS YP_043506.1 49486285 2863561 complement(1511752..1512096) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1457; hypothetical protein 1512096 2863561 SAS1388 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043506.1 1511752 R 282459 CDS YP_043507.1 49486286 2863562 complement(1512110..1512673) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1458; hypothetical protein 1512673 2863562 SAS1389 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043507.1 1512110 R 282459 CDS YP_043508.1 49486287 2863590 complement(1512666..1513016) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1459; hypothetical protein 1513016 2863590 SAS1390 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043508.1 1512666 R 282459 CDS YP_043509.1 49486288 2863591 complement(1513070..1513249) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1459a; No significant database matches; hypothetical protein 1513249 2863591 SAS1391 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043509.1 1513070 R 282459 CDS YP_043510.1 49486289 2862960 1513555..1514181 1 NC_002953.3 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease 1514181 recU 2862960 recU Staphylococcus aureus subsp. aureus MSSA476 Holliday junction-specific endonuclease YP_043510.1 1513555 D 282459 CDS YP_043511.1 49486290 2862961 1514178..1516361 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1461; penicillin-binding protein 2 1516361 2862961 SAS1393 Staphylococcus aureus subsp. aureus MSSA476 penicillin-binding protein 2 YP_043511.1 1514178 D 282459 CDS YP_043512.1 49486291 2864448 complement(1516925..1517266) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1462; hypothetical protein 1517266 2864448 SAS1394 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043512.1 1516925 R 282459 CDS YP_043513.1 49486292 2864449 complement(1517271..1517930) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1463; endonuclease 1517930 2864449 SAS1395 Staphylococcus aureus subsp. aureus MSSA476 endonuclease YP_043513.1 1517271 R 282459 CDS YP_043514.1 49486293 2861820 complement(1517920..1518606) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1464; hypothetical protein 1518606 2861820 SAS1396 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043514.1 1517920 R 282459 CDS YP_043515.1 49486294 2864026 complement(1518934..1520226) 1 NC_002953.3 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1520226 asnC 2864026 asnC Staphylococcus aureus subsp. aureus MSSA476 asparaginyl-tRNA synthetase YP_043515.1 1518934 R 282459 CDS YP_043516.1 49486295 2864027 complement(1520548..1523241) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1466; hypothetical protein 1523241 2864027 SAS1398 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043516.1 1520548 R 282459 CDS YP_043517.1 49486296 2864429 complement(1523265..1524236) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1467; BirA bifunctional protein [includes: biotin operon repressor; biotin--[acetyl-CoA-carboxylase] synthetase 1524236 2864429 SAS1399 Staphylococcus aureus subsp. aureus MSSA476 BirA bifunctional protein [includes: biotin operon repressor; biotin--[acetyl-CoA-carboxylase] synthetase YP_043517.1 1523265 R 282459 CDS YP_043518.1 49486297 2864430 complement(1524223..1525425) 1 NC_002953.3 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 1525425 2864430 SAS1400 Staphylococcus aureus subsp. aureus MSSA476 tRNA CCA-pyrophosphorylase YP_043518.1 1524223 R 282459 CDS YP_043519.1 49486298 2864458 complement(1525430..1526572) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1469; glycosyl transferase family protein 1526572 2864458 SAS1401 Staphylococcus aureus subsp. aureus MSSA476 glycosyl transferase family protein YP_043519.1 1525430 R 282459 CDS YP_043520.1 49486299 2864459 complement(1526814..1527131) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1470; hypothetical protein 1527131 2864459 SAS1402 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043520.1 1526814 R 282459 CDS YP_043521.1 49486300 2862745 complement(1527467..1528165) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1471; hypothetical protein 1528165 2862745 SAS1403 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043521.1 1527467 R 282459 CDS YP_043522.1 49486301 2862746 complement(1528219..1528806) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1472; hypothetical protein 1528806 2862746 SAS1404 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043522.1 1528219 R 282459 CDS YP_043523.1 49486302 2863257 complement(1528796..1529371) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1473; hypothetical protein 1529371 2863257 SAS1405 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043523.1 1528796 R 282459 CDS YP_043524.1 49486303 2862657 complement(1529385..1530629) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1474; hypothetical protein 1530629 2862657 SAS1406 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043524.1 1529385 R 282459 CDS YP_043525.1 49486304 2862658 complement(1530636..1531934) 1 NC_002953.3 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1531934 2862658 SAS1407 Staphylococcus aureus subsp. aureus MSSA476 3-phosphoshikimate 1-carboxyvinyltransferase YP_043525.1 1530636 R 282459 CDS YP_043526.1 49486305 2862636 complement(1531944..1533008) 1 NC_002953.3 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1533008 aroB 2862636 aroB Staphylococcus aureus subsp. aureus MSSA476 3-dehydroquinate synthase YP_043526.1 1531944 R 282459 CDS YP_043527.1 49486306 2862637 complement(1533034..1534200) 1 NC_002953.3 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 1534200 2862637 SAS1409 Staphylococcus aureus subsp. aureus MSSA476 chorismate synthase YP_043527.1 1533034 R 282459 CDS YP_043528.1 49486307 2863473 complement(1534588..1534788) 1 NC_002953.3 Doubtful CDS. No database matches; hypothetical protein 1534788 2863473 SAS1409a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043528.1 1534588 R 282459 CDS YP_043529.1 49486308 2863474 complement(1534998..1535447) 1 NC_002953.3 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1535447 ndk 2863474 ndk Staphylococcus aureus subsp. aureus MSSA476 nucleoside diphosphate kinase YP_043529.1 1534998 R 282459 CDS YP_043530.1 49486309 2863276 complement(1535539..1536498) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1479; heptaprenyl diphosphate synthase component II 1536498 2863276 SAS1411 Staphylococcus aureus subsp. aureus MSSA476 heptaprenyl diphosphate synthase component II YP_043530.1 1535539 R 282459 CDS YP_043531.1 49486310 2863277 complement(1536500..1537225) 1 NC_002953.3 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 1537225 ubiE 2863277 ubiE Staphylococcus aureus subsp. aureus MSSA476 ubiquinone/menaquinone biosynthesis methyltransferase YP_043531.1 1536500 R 282459 CDS YP_043532.1 49486311 2862607 complement(1537228..1537800) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1481; hypothetical protein 1537800 2862607 SAS1413 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043532.1 1537228 R 282459 CDS YP_043533.1 49486312 2863258 complement(1538231..1538503) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1482; DNA-binding protein HU 1538503 2863258 SAS1414 Staphylococcus aureus subsp. aureus MSSA476 DNA-binding protein HU YP_043533.1 1538231 R 282459 CDS YP_043534.1 49486313 2863259 complement(1538674..1539672) 1 NC_002953.3 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1539672 gpsA 2863259 gpsA Staphylococcus aureus subsp. aureus MSSA476 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_043534.1 1538674 R 282459 CDS YP_043535.1 49486314 2863460 complement(1539689..1540999) 1 NC_002953.3 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 1540999 engA 2863460 engA Staphylococcus aureus subsp. aureus MSSA476 GTP-binding protein EngA YP_043535.1 1539689 R 282459 CDS YP_043536.1 49486315 2863461 complement(1541221..1542396) 1 NC_002953.3 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1542396 rpsA 2863461 rpsA Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S1 YP_043536.1 1541221 R 282459 CDS YP_043537.1 49486316 2862611 complement(1543094..1543753) 1 NC_002953.3 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1543753 cmk 2862611 cmk Staphylococcus aureus subsp. aureus MSSA476 cytidylate kinase YP_043537.1 1543094 R 282459 CDS YP_043538.1 49486317 2862612 1543830..1544798 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1487; L-asparaginase 1544798 2862612 SAS1419 Staphylococcus aureus subsp. aureus MSSA476 L-asparaginase YP_043538.1 1543830 D 282459 CDS YP_043539.1 49486318 2862616 complement(1544913..1545899) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1488; pyridine nucleotide-disulfide oxidoreductase 1545899 2862616 SAS1420 Staphylococcus aureus subsp. aureus MSSA476 pyridine nucleotide-disulfide oxidoreductase YP_043539.1 1544913 R 282459 CDS YP_043540.1 49486319 2862617 complement(1546301..1547761) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1489; cell surface elastin binding protein 1547761 2862617 SAS1421 Staphylococcus aureus subsp. aureus MSSA476 cell surface elastin binding protein YP_043540.1 1546301 R 282459 CDS YP_043541.1 49486320 2862623 complement(1547914..1549293) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1490; DEAD/DEAH box helicase 1549293 2862623 SAS1422 Staphylococcus aureus subsp. aureus MSSA476 DEAD/DEAH box helicase YP_043541.1 1547914 R 282459 CDS YP_043542.1 49486321 2864140 complement(1549283..1550236) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1491; hypothetical protein 1550236 2864140 SAS1423 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043542.1 1549283 R 282459 CDS YP_043543.1 49486322 2864141 1550344..1550592 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1492; ferredoxin 1550592 2864141 SAS1424 Staphylococcus aureus subsp. aureus MSSA476 ferredoxin YP_043543.1 1550344 D 282459 CDS YP_043544.1 49486323 2863624 complement(1550698..1551243) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1493; hypothetical protein 1551243 2863624 SAS1425 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043544.1 1550698 R 282459 CDS YP_043545.1 49486324 2863625 complement(1551653..1552567) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1565; lipoprotein 1552567 2863625 SAS1426 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_043545.1 1551653 R 282459 CDS YP_043546.1 49486325 2863684 complement(1552624..1553541) 1 NC_002953.3 lipoprotein 1553541 2863684 SAS1427 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_043546.1 1552624 R 282459 CDS YP_043547.1 49486326 2863685 complement(1553599..1554504) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1495; lipoprotein 1554504 2863685 SAS1428 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_043547.1 1553599 R 282459 CDS YP_043548.1 49486327 2862572 complement(1554595..1556757) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1563; No significant database matches; hypothetical protein 1556757 2862572 SAS1429 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043548.1 1554595 R 282459 CDS YP_043549.1 49486328 2862573 complement(1556769..1557677) 1 NC_002953.3 lipoprotein 1557677 2862573 SAS1430 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_043549.1 1556769 R 282459 CDS YP_043550.1 49486329 2862266 complement(1557922..1559688) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1567; sensor kinase 1559688 2862266 SAS1431 Staphylococcus aureus subsp. aureus MSSA476 sensor kinase YP_043550.1 1557922 R 282459 CDS YP_043551.1 49486330 2864155 complement(1559654..1560397) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1568; response regulator protein 1560397 2864155 SAS1432 Staphylococcus aureus subsp. aureus MSSA476 response regulator protein YP_043551.1 1559654 R 282459 CDS YP_043552.1 49486331 2864156 complement(1560512..1561249) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1569; ribosomal large subunit pseudouridine synthase B 1561249 2864156 SAS1433 Staphylococcus aureus subsp. aureus MSSA476 ribosomal large subunit pseudouridine synthase B YP_043552.1 1560512 R 282459 CDS YP_043553.1 49486332 2861981 complement(1561242..1561784) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1570; hypothetical protein 1561784 2861981 SAS1434 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043553.1 1561242 R 282459 CDS YP_043554.1 49486333 2861982 complement(1561777..1562532) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1571; hypothetical protein 1562532 2861982 SAS1435 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043554.1 1561777 R 282459 CDS YP_043555.1 49486334 2863603 1562600..1563106 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1572; hypothetical protein 1563106 2863603 SAS1436 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043555.1 1562600 D 282459 CDS YP_043556.1 49486335 2863604 complement(1563184..1564071) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1573; integrase/recombinase 1564071 2863604 SAS1437 Staphylococcus aureus subsp. aureus MSSA476 integrase/recombinase YP_043556.1 1563184 R 282459 CDS YP_043557.1 49486336 2862540 complement(1564120..1564569) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1574; iron uptake regulatory protein 1564569 2862540 SAS1438 Staphylococcus aureus subsp. aureus MSSA476 iron uptake regulatory protein YP_043557.1 1564120 R 282459 CDS YP_043558.1 49486337 2862541 complement(1564674..1565216) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1575; ADP-ribose pyrophosphatase 1565216 2862541 SAS1439 Staphylococcus aureus subsp. aureus MSSA476 ADP-ribose pyrophosphatase YP_043558.1 1564674 R 282459 CDS YP_043559.1 49486338 2863407 1565298..1566206 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1576; aldo/keto reductase 1566206 2863407 SAS1440 Staphylococcus aureus subsp. aureus MSSA476 aldo/keto reductase YP_043559.1 1565298 D 282459 CDS YP_043560.1 49486339 2862719 complement(1566422..1566670) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1577; hypothetical protein 1566670 2862719 SAS1441 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043560.1 1566422 R 282459 CDS YP_043561.1 49486340 2862720 complement(1566686..1567444) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1578; short chain dehydrogenase 1567444 2862720 SAS1442 Staphylococcus aureus subsp. aureus MSSA476 short chain dehydrogenase YP_043561.1 1566686 R 282459 CDS YP_043562.1 49486341 2863176 1567583..1568398 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1579; pyrroline-5-carboxylate reductase 1568398 2863176 SAS1443 Staphylococcus aureus subsp. aureus MSSA476 pyrroline-5-carboxylate reductase YP_043562.1 1567583 D 282459 CDS YP_043563.1 49486342 2863177 complement(1568501..1569421) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1581; hypothetical protein 1569421 2863177 SAS1444 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043563.1 1568501 R 282459 CDS YP_043564.1 49486343 2863509 1569734..1571218 1 NC_002953.3 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1571218 2863509 SAS1445 Staphylococcus aureus subsp. aureus MSSA476 glucose-6-phosphate 1-dehydrogenase YP_043564.1 1569734 D 282459 CDS YP_043565.1 49486344 2863510 1571448..1572314 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1583; AraC family transcriptional regulator 1572314 2863510 SAS1446 Staphylococcus aureus subsp. aureus MSSA476 AraC family transcriptional regulator YP_043565.1 1571448 D 282459 CDS YP_043566.1 49486345 2862900 complement(1572396..1574045) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1584; alpha-D-1,4-glucosidase 1574045 2862900 SAS1447 Staphylococcus aureus subsp. aureus MSSA476 alpha-D-1,4-glucosidase YP_043566.1 1572396 R 282459 CDS YP_043567.1 49486346 2862901 complement(1574061..1575080) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1585; maltose operon transcriptional repressor 1575080 2862901 SAS1448 Staphylococcus aureus subsp. aureus MSSA476 maltose operon transcriptional repressor YP_043567.1 1574061 R 282459 CDS YP_043568.1 49486347 2862809 complement(1575274..1575645) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1586; glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein 1575645 2862809 SAS1449 Staphylococcus aureus subsp. aureus MSSA476 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein YP_043568.1 1575274 R 282459 CDS YP_043569.1 49486348 2862231 complement(1575864..1577270) 1 NC_002953.3 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 1577270 2862231 SAS1450 Staphylococcus aureus subsp. aureus MSSA476 6-phosphogluconate dehydrogenase YP_043569.1 1575864 R 282459 CDS YP_043570.1 49486349 2862232 complement(1577338..1578471) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1590; peptidase 1578471 2862232 SAS1451 Staphylococcus aureus subsp. aureus MSSA476 peptidase YP_043570.1 1577338 R 282459 CDS YP_043571.1 49486350 2862500 complement(1579040..1580020) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1591; hypothetical protein 1580020 2862500 SAS1452 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043571.1 1579040 R 282459 CDS YP_043572.1 49486351 2862501 complement(1580034..1580471) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1592; hypothetical protein 1580471 2862501 SAS1453 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043572.1 1580034 R 282459 CDS YP_043573.1 49486352 2862380 complement(1580822..1582096) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1593; lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex 1582096 2862380 SAS1454 Staphylococcus aureus subsp. aureus MSSA476 lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex YP_043573.1 1580822 R 282459 CDS YP_043574.1 49486353 2862381 complement(1582109..1583092) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1594; 2-oxoisovalerate dehydrogenase subunit beta 1583092 2862381 SAS1455 Staphylococcus aureus subsp. aureus MSSA476 2-oxoisovalerate dehydrogenase subunit beta YP_043574.1 1582109 R 282459 CDS YP_043575.1 49486354 2862371 complement(1583092..1584084) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1595; 2-oxoisovalerate dehydrogenase subunit alpha 1584084 2862371 SAS1456 Staphylococcus aureus subsp. aureus MSSA476 2-oxoisovalerate dehydrogenase subunit alpha YP_043575.1 1583092 R 282459 CDS YP_043576.1 49486355 2862372 complement(1584100..1585521) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1596; dihydrolipoamide dehydrogenase 1585521 2862372 SAS1457 Staphylococcus aureus subsp. aureus MSSA476 dihydrolipoamide dehydrogenase YP_043576.1 1584100 R 282459 CDS YP_043577.1 49486356 2862386 complement(1585672..1587351) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1597; DNA repair protein 1587351 2862386 SAS1458 Staphylococcus aureus subsp. aureus MSSA476 DNA repair protein YP_043577.1 1585672 R 282459 CDS YP_043578.1 49486357 2862795 complement(1587367..1587819) 1 NC_002953.3 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 1587819 2862795 SAS1459 Staphylococcus aureus subsp. aureus MSSA476 arginine repressor ArgR YP_043578.1 1587367 R 282459 CDS YP_043579.1 49486358 2862796 complement(1588251..1589132) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1599; geranyltranstransferase 1589132 2862796 SAS1460 Staphylococcus aureus subsp. aureus MSSA476 geranyltranstransferase YP_043579.1 1588251 R 282459 CDS YP_043580.1 49486359 2864355 complement(1589110..1589340) 1 NC_002953.3 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1589340 2864355 SAS1461 Staphylococcus aureus subsp. aureus MSSA476 exodeoxyribonuclease VII small subunit YP_043580.1 1589110 R 282459 CDS YP_043581.1 49486360 2864356 complement(1589333..1590670) 1 NC_002953.3 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1590670 xseA 2864356 xseA Staphylococcus aureus subsp. aureus MSSA476 exodeoxyribonuclease VII large subunit YP_043581.1 1589333 R 282459 CDS YP_043582.1 49486361 2863505 complement(1590687..1591076) 1 NC_002953.3 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 1591076 nusB 2863505 nusB Staphylococcus aureus subsp. aureus MSSA476 transcription antitermination protein NusB YP_043582.1 1590687 R 282459 CDS YP_043583.1 49486362 2863506 complement(1591136..1591498) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1603; hypothetical protein 1591498 2863506 SAS1464 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043583.1 1591136 R 282459 CDS YP_043584.1 49486363 2863501 complement(1591513..1592868) 1 NC_002953.3 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 1592868 2863501 SAS1465 Staphylococcus aureus subsp. aureus MSSA476 acetyl-CoA carboxylase biotin carboxylase subunit YP_043584.1 1591513 R 282459 CDS YP_043585.1 49486364 2863502 complement(1592868..1593332) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1605; biotin carboxyl carrier protein of acetyl-CoA carboxylase 1593332 2863502 SAS1466 Staphylococcus aureus subsp. aureus MSSA476 biotin carboxyl carrier protein of acetyl-CoA carboxylase YP_043585.1 1592868 R 282459 CDS YP_043586.1 49486365 2863403 complement(1593806..1594363) 1 NC_002953.3 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1594363 2863403 SAS1467 Staphylococcus aureus subsp. aureus MSSA476 elongation factor P YP_043586.1 1593806 R 282459 CDS YP_043587.1 49486366 2863398 complement(1594389..1595450) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1607; peptidase 1595450 2863398 SAS1468 Staphylococcus aureus subsp. aureus MSSA476 peptidase YP_043587.1 1594389 R 282459 CDS YP_043588.1 49486367 2863399 1595555..1596136 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1608; hypothetical protein 1596136 2863399 SAS1469 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043588.1 1595555 D 282459 CDS YP_043589.1 49486368 2862738 1596150..1596368 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1609; hypothetical protein 1596368 2862738 SAS1470 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043589.1 1596150 D 282459 CDS YP_043590.1 49486369 2862739 complement(1596432..1597262) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1610; lipoate-protein ligase A 1597262 2862739 SAS1471 Staphylococcus aureus subsp. aureus MSSA476 lipoate-protein ligase A YP_043590.1 1596432 R 282459 CDS YP_043591.1 49486370 2862704 1597420..1597806 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1611; hypothetical protein 1597806 2862704 SAS1472 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043591.1 1597420 D 282459 CDS YP_043592.1 49486371 2862705 complement(1598171..1599643) 1 NC_002953.3 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; glycine dehydrogenase subunit 2 1599643 2862705 SAS1473 Staphylococcus aureus subsp. aureus MSSA476 glycine dehydrogenase subunit 2 YP_043592.1 1598171 R 282459 CDS YP_043593.1 49486372 2863395 complement(1599636..1600991) 1 NC_002953.3 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein; glycine dehydrogenase subunit 1 1600991 2863395 SAS1474 Staphylococcus aureus subsp. aureus MSSA476 glycine dehydrogenase subunit 1 YP_043593.1 1599636 R 282459 CDS YP_043594.1 49486373 2863396 complement(1601002..1602093) 1 NC_002953.3 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 1602093 gcvT 2863396 gcvT Staphylococcus aureus subsp. aureus MSSA476 glycine cleavage system aminomethyltransferase T YP_043594.1 1601002 R 282459 CDS YP_043595.1 49486374 2862906 complement(1602252..1602776) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1615; shikimate kinase 1602776 2862906 SAS1476 Staphylococcus aureus subsp. aureus MSSA476 shikimate kinase YP_043595.1 1602252 R 282459 CDS YP_043596.1 49486375 2862331 complement(1603009..1603506) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1616; hypothetical protein 1603506 2862331 SAS1477 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043596.1 1603009 R 282459 CDS YP_043597.1 49486376 2862332 complement(1603424..1603723) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1617; hypothetical protein 1603723 2862332 SAS1478 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043597.1 1603424 R 282459 CDS YP_043598.1 49486377 2861942 complement(1603710..1604144) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1618; hypothetical protein 1604144 2861942 SAS1479 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043598.1 1603710 R 282459 CDS YP_043599.1 49486378 2861943 complement(1604134..1604445) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1619; hypothetical protein 1604445 2861943 SAS1480 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043599.1 1604134 R 282459 CDS YP_043600.1 49486379 2861940 complement(1604459..1605529) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1620; hypothetical protein 1605529 2861940 SAS1481 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043600.1 1604459 R 282459 CDS YP_043601.1 49486380 2861941 complement(1605501..1606475) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1621; hypothetical protein 1606475 2861941 SAS1482 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043601.1 1605501 R 282459 CDS YP_043602.1 49486381 2861935 complement(1606527..1607150) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1622; metallo-beta-lactamase superfamily protein 1607150 2861935 SAS1483 Staphylococcus aureus subsp. aureus MSSA476 metallo-beta-lactamase superfamily protein YP_043602.1 1606527 R 282459 CDS YP_043603.1 49486382 2861936 complement(1607147..1607476) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1623; hypothetical protein 1607476 2861936 SAS1484 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043603.1 1607147 R 282459 CDS YP_043604.1 49486383 2861928 complement(1607476..1608462) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1624; glucokinase 1608462 2861928 SAS1485 Staphylococcus aureus subsp. aureus MSSA476 glucokinase YP_043604.1 1607476 R 282459 CDS YP_043605.1 49486384 2861923 complement(1608459..1608662) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1625; hypothetical protein 1608662 2861923 SAS1486 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043605.1 1608459 R 282459 CDS YP_043606.1 49486385 2861924 complement(1608643..1610106) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1626; hypothetical protein 1610106 2861924 SAS1487 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043606.1 1608643 R 282459 CDS YP_043607.1 49486386 2861919 complement(1610118..1610657) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1627; 5-formyltetrahydrofolate cyclo-ligase 1610657 2861919 SAS1488 Staphylococcus aureus subsp. aureus MSSA476 5-formyltetrahydrofolate cyclo-ligase YP_043607.1 1610118 R 282459 CDS YP_043608.1 49486387 2861920 complement(1610866..1611015) 1 NC_002953.3 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1611015 rpmG 2861920 rpmG Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L33 YP_043608.1 1610866 R 282459 CDS YP_043609.1 49486388 2861917 complement(1611128..1613203) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1629; penicillin-binding protein 3 1613203 2861917 SAS1490 Staphylococcus aureus subsp. aureus MSSA476 penicillin-binding protein 3 YP_043609.1 1611128 R 282459 CDS YP_043610.1 49486389 2861918 complement(1613324..1613923) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1630; superoxide dismutase 1613923 2861918 SAS1491 Staphylococcus aureus subsp. aureus MSSA476 superoxide dismutase YP_043610.1 1613324 R 282459 CDS YP_043611.1 49486390 2861914 complement(1614199..1614609) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1631; zinc-specific metalloregulatory protein 1614609 2861914 SAS1492 Staphylococcus aureus subsp. aureus MSSA476 zinc-specific metalloregulatory protein YP_043611.1 1614199 R 282459 CDS YP_043612.1 49486391 2861915 complement(1614596..1615459) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1632; ABC transporter permease 1615459 2861915 SAS1493 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter permease YP_043612.1 1614596 R 282459 CDS YP_043613.1 49486392 2861912 complement(1615501..1616286) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1633; ABC transporter ATP-binding protein 1616286 2861912 SAS1494 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_043613.1 1615501 R 282459 CDS YP_043614.1 49486393 2861906 complement(1616412..1617302) 1 NC_002953.3 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 1617302 2861906 SAS1495 Staphylococcus aureus subsp. aureus MSSA476 endonuclease IV YP_043614.1 1616412 R 282459 CDS YP_043615.1 49486394 2861907 complement(1617312..1618658) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1635; helicase 1618658 2861907 SAS1496 Staphylococcus aureus subsp. aureus MSSA476 helicase YP_043615.1 1617312 R 282459 CDS YP_043616.1 49486395 2861904 complement(1618772..1619872) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1636; hypothetical protein 1619872 2861904 SAS1497 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043616.1 1618772 R 282459 CDS YP_043617.1 49486396 2861905 complement(1619875..1620552) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1637; hypothetical protein 1620552 2861905 SAS1498 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043617.1 1619875 R 282459 CDS YP_043618.1 49486397 2861902 complement(1620683..1621789) 1 NC_002953.3 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 1621789 2861902 SAS1499 Staphylococcus aureus subsp. aureus MSSA476 RNA polymerase sigma factor RpoD YP_043618.1 1620683 R 282459 CDS YP_043619.1 49486398 2861903 complement(1622013..1623830) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1639; DNA primase 1623830 2861903 SAS1500 Staphylococcus aureus subsp. aureus MSSA476 DNA primase YP_043619.1 1622013 R 282459 CDS YP_043620.1 49486399 2861900 complement(1623891..1624709) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1640; hypothetical protein 1624709 2861900 SAS1501 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043620.1 1623891 R 282459 CDS YP_043621.1 49486400 2861896 1625678..1627069 1 NC_002953.3 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase 1627069 2861896 SAS1503 Staphylococcus aureus subsp. aureus MSSA476 glycyl-tRNA synthetase YP_043621.1 1625678 D 282459 CDS YP_043622.1 49486401 2861888 complement(1627220..1627972) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1643; recombination protein O 1627972 2861888 SAS1504 Staphylococcus aureus subsp. aureus MSSA476 recombination protein O YP_043622.1 1627220 R 282459 CDS YP_043623.1 49486402 2861889 complement(1627994..1628893) 1 NC_002953.3 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1628893 era 2861889 era Staphylococcus aureus subsp. aureus MSSA476 GTP-binding protein Era YP_043623.1 1627994 R 282459 CDS YP_043624.1 49486403 2862729 complement(1628894..1629298) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1645; cytidine deaminase 1629298 2862729 SAS1506 Staphylococcus aureus subsp. aureus MSSA476 cytidine deaminase YP_043624.1 1628894 R 282459 CDS YP_043625.1 49486404 2862730 complement(1629309..1629653) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1646; diacylglycerol kinase 1629653 2862730 SAS1507 Staphylococcus aureus subsp. aureus MSSA476 diacylglycerol kinase YP_043625.1 1629309 R 282459 CDS YP_043626.1 49486405 2862878 complement(1629656..1630123) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1647; hypothetical protein 1630123 2862878 SAS1508 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043626.1 1629656 R 282459 CDS YP_043627.1 49486406 2862879 complement(1630124..1631071) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1648; PhoH-like protein 1631071 2862879 SAS1509 Staphylococcus aureus subsp. aureus MSSA476 PhoH-like protein YP_043627.1 1630124 R 282459 CDS YP_043628.1 49486407 2861894 complement(1631375..1632073) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1649; hypothetical protein 1632073 2861894 SAS1510 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043628.1 1631375 R 282459 CDS YP_043629.1 49486408 2861895 complement(1632090..1633079) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1650; hypothetical protein 1633079 2861895 SAS1511 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043629.1 1632090 R 282459 CDS YP_043630.1 49486409 2861916 complement(1633097..1633804) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1651; hypothetical protein 1633804 2861916 SAS1512 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043630.1 1633097 R 282459 CDS YP_043631.1 49486410 2861892 complement(1634024..1634200) 1 NC_002953.3 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 1634200 rpsU 2861892 rpsU Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S21 YP_043631.1 1634024 R 282459 CDS YP_043632.1 49486411 2861893 complement(1634493..1635839) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1653; hypothetical protein 1635839 2861893 SAS1514 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043632.1 1634493 R 282459 CDS YP_043633.1 49486412 2863768 complement(1635846..1636598) 1 NC_002953.3 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1636598 2863768 SAS1515 Staphylococcus aureus subsp. aureus MSSA476 16S ribosomal RNA methyltransferase RsmE YP_043633.1 1635846 R 282459 CDS YP_043634.1 49486413 2863769 complement(1636600..1637538) 1 NC_002953.3 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 1637538 prmA 2863769 prmA Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L11 methyltransferase YP_043634.1 1636600 R 282459 CDS YP_043635.1 49486414 2863733 complement(1637542..1638681) 1 NC_002953.3 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 1638681 2863733 SAS1517 Staphylococcus aureus subsp. aureus MSSA476 molecular chaperone DnaJ YP_043635.1 1637542 R 282459 CDS YP_043636.1 49486415 2863734 complement(1638817..1640649) 1 NC_002953.3 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 1640649 dnaK 2863734 dnaK Staphylococcus aureus subsp. aureus MSSA476 molecular chaperone DnaK YP_043636.1 1638817 R 282459 CDS YP_043637.1 49486416 2862384 complement(1640718..1641344) 1 NC_002953.3 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 1641344 2862384 SAS1519 Staphylococcus aureus subsp. aureus MSSA476 heat shock protein GrpE YP_043637.1 1640718 R 282459 CDS YP_043638.1 49486417 2862385 complement(1641376..1642353) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1659; heat-inducible transcription repressor 1642353 2862385 SAS1520 Staphylococcus aureus subsp. aureus MSSA476 heat-inducible transcription repressor YP_043638.1 1641376 R 282459 CDS YP_043639.1 49486418 2863724 complement(1642454..1643578) 1 NC_002953.3 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1643578 2863724 SAS1521 Staphylococcus aureus subsp. aureus MSSA476 coproporphyrinogen III oxidase YP_043639.1 1642454 R 282459 CDS YP_043640.1 49486419 2864260 complement(1644144..1645967) 1 NC_002953.3 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1645967 2864260 SAS1522 Staphylococcus aureus subsp. aureus MSSA476 GTP-binding protein LepA YP_043640.1 1644144 R 282459 CDS YP_043641.1 49486420 2864261 1646313..1646564 1 NC_002953.3 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1646564 rpsT 2864261 rpsT Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S20 YP_043641.1 1646313 D 282459 CDS YP_043642.1 49486421 2863728 complement(1646609..1647583) 1 NC_002953.3 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 1647583 holA 2863728 holA Staphylococcus aureus subsp. aureus MSSA476 DNA polymerase III subunit delta YP_043642.1 1646609 R 282459 CDS YP_043643.1 49486422 2863729 complement(1647640..1649841) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1665; hypothetical protein 1649841 2863729 SAS1525 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043643.1 1647640 R 282459 CDS YP_043644.1 49486423 2863714 complement(1649846..1650307) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1666; deaminase 1650307 2863714 SAS1526 Staphylococcus aureus subsp. aureus MSSA476 deaminase YP_043644.1 1649846 R 282459 CDS YP_043645.1 49486424 2863715 complement(1650399..1651076) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1667; hypothetical protein 1651076 2863715 SAS1527 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043645.1 1650399 R 282459 CDS YP_043646.1 49486425 2862162 complement(1651125..1651841) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1668; hypothetical protein 1651841 2862162 SAS1528 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043646.1 1651125 R 282459 CDS YP_043647.1 49486426 2862163 complement(1651844..1652197) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1669; hypothetical protein 1652197 2862163 SAS1529 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043647.1 1651844 R 282459 CDS YP_043648.1 49486427 2863721 complement(1652198..1652782) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1670; hypothetical protein 1652782 2863721 SAS1530 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043648.1 1652198 R 282459 CDS YP_043649.1 49486428 2862829 complement(1652772..1653341) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1671; hypothetical protein 1653341 2862829 SAS1531 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043649.1 1652772 R 282459 CDS YP_043650.1 49486429 2862830 complement(1653344..1653634) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1672; hypothetical protein 1653634 2862830 SAS1532 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043650.1 1653344 R 282459 CDS YP_043651.1 49486430 2863900 complement(1653638..1654444) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1673; shikimate 5-dehydrogenase 1654444 2863900 SAS1533 Staphylococcus aureus subsp. aureus MSSA476 shikimate 5-dehydrogenase YP_043651.1 1653638 R 282459 CDS YP_043652.1 49486431 2863901 complement(1654458..1655558) 1 NC_002953.3 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH 1655558 2863901 SAS1534 Staphylococcus aureus subsp. aureus MSSA476 GTP-binding protein YqeH YP_043652.1 1654458 R 282459 CDS YP_043653.1 49486432 2862057 complement(1655559..1656086) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1675; hypothetical protein 1656086 2862057 SAS1535 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043653.1 1655559 R 282459 CDS YP_043654.1 49486433 2862058 complement(1656106..1656792) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1676; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1656792 2862058 SAS1536 Staphylococcus aureus subsp. aureus MSSA476 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_043654.1 1656106 R 282459 CDS YP_043655.1 49486434 2863717 1657106..1657375 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1677; hypothetical protein 1657375 2863717 SAS1537 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043655.1 1657106 D 282459 CDS YP_043656.1 49486435 2863718 complement(1657577..1658266) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1679; enterotoxin 1658266 2863718 SAS1538 Staphylococcus aureus subsp. aureus MSSA476 enterotoxin YP_043656.1 1657577 R 282459 CDS YP_043657.1 49486436 2863328 complement(1659036..1660256) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1682; hypothetical protein 1660256 2863328 SAS1539 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043657.1 1659036 R 282459 CDS YP_043658.1 49486437 2862051 complement(1660543..1661772) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1683; hypothetical protein 1661772 2862051 SAS1540 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043658.1 1660543 R 282459 CDS YP_043659.1 49486438 2862052 complement(1661784..1662536) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1684; LamB/YcsF family protein 1662536 2862052 SAS1541 Staphylococcus aureus subsp. aureus MSSA476 LamB/YcsF family protein YP_043659.1 1661784 R 282459 CDS YP_043660.1 49486439 2862200 complement(1662536..1663897) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1685; biotin carboxylase 1663897 2862200 SAS1542 Staphylococcus aureus subsp. aureus MSSA476 biotin carboxylase YP_043660.1 1662536 R 282459 CDS YP_043661.1 49486440 2862201 complement(1663911..1664360) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1686; biotin carboxyl carrier protein of acetyl-CoA carboxylase 1664360 2862201 SAS1543 Staphylococcus aureus subsp. aureus MSSA476 biotin carboxyl carrier protein of acetyl-CoA carboxylase YP_043661.1 1663911 R 282459 CDS YP_043662.1 49486441 2863904 complement(1664362..1665372) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1687; hypothetical protein 1665372 2863904 SAS1544 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043662.1 1664362 R 282459 CDS YP_043663.1 49486442 2863905 complement(1665362..1666096) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1688; hypothetical protein 1666096 2863905 SAS1545 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043663.1 1665362 R 282459 CDS YP_043664.1 49486443 2863861 complement(1666422..1666898) 1 NC_002953.3 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1666898 greA 2863861 greA Staphylococcus aureus subsp. aureus MSSA476 transcription elongation factor GreA YP_043664.1 1666422 R 282459 CDS YP_043665.1 49486444 2863862 complement(1666926..1667549) 1 NC_002953.3 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1667549 2863862 SAS1547 Staphylococcus aureus subsp. aureus MSSA476 uridine kinase YP_043665.1 1666926 R 282459 CDS YP_043666.1 49486445 2862417 complement(1667549..1668817) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1691; peptidase 1668817 2862417 SAS1548 Staphylococcus aureus subsp. aureus MSSA476 peptidase YP_043666.1 1667549 R 282459 CDS YP_043667.1 49486446 2862848 complement(1668829..1669752) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1692; peptidase 1669752 2862848 SAS1549 Staphylococcus aureus subsp. aureus MSSA476 peptidase YP_043667.1 1668829 R 282459 CDS YP_043668.1 49486447 2862849 complement(1669755..1670393) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1693; O-methyltransferase 1670393 2862849 SAS1550 Staphylococcus aureus subsp. aureus MSSA476 O-methyltransferase YP_043668.1 1669755 R 282459 CDS YP_043669.1 49486448 2862209 complement(1670678..1670986) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1694; hypothetical protein 1670986 2862209 SAS1551 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043669.1 1670678 R 282459 CDS YP_043670.1 49486449 2862210 complement(1671001..1671429) 1 NC_002953.3 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 1671429 2862210 SAS1552 Staphylococcus aureus subsp. aureus MSSA476 Holliday junction resolvase-like protein YP_043670.1 1671001 R 282459 CDS YP_043671.1 49486450 2863143 complement(1671433..1671693) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1696; hypothetical protein 1671693 2863143 SAS1553 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043671.1 1671433 R 282459 CDS YP_043672.1 49486451 2863144 complement(1671756..1674386) 1 NC_002953.3 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1674386 alaS 2863144 alaS Staphylococcus aureus subsp. aureus MSSA476 alanyl-tRNA synthetase YP_043672.1 1671756 R 282459 CDS YP_043673.1 49486452 2863154 complement(1674729..1677206) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1698; hypothetical protein 1677206 2863154 SAS1555 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043673.1 1674729 R 282459 CDS YP_043674.1 49486453 2863155 complement(1677208..1677876) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1699; hypothetical protein 1677876 2863155 SAS1556 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043674.1 1677208 R 282459 CDS YP_043675.1 49486454 2862890 complement(1678457..1679575) 1 NC_002953.3 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1679575 mnmA 2862890 mnmA Staphylococcus aureus subsp. aureus MSSA476 tRNA-specific 2-thiouridylase MnmA YP_043675.1 1678457 R 282459 CDS YP_043676.1 49486455 2862944 complement(1679576..1680718) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1702; cysteine desulfurase 1680718 2862944 SAS1558 Staphylococcus aureus subsp. aureus MSSA476 cysteine desulfurase YP_043676.1 1679576 R 282459 CDS YP_043677.1 49486456 2862945 1681030..1682043 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1703; oxygenase 1682043 2862945 SAS1559 Staphylococcus aureus subsp. aureus MSSA476 oxygenase YP_043677.1 1681030 D 282459 CDS YP_043678.1 49486457 2863170 complement(1682280..1682426) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1704; hypothetical protein 1682426 2863170 SAS1560 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043678.1 1682280 R 282459 CDS YP_043679.1 49486458 2863171 complement(1682466..1682648) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1705; hypothetical protein 1682648 2863171 SAS1561 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043679.1 1682466 R 282459 CDS YP_043680.1 49486459 2863551 complement(1682748..1683170) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1706; hypothetical protein 1683170 2863551 SAS1562 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043680.1 1682748 R 282459 CDS YP_043681.1 49486460 2863552 1683255..1684529 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1707; recombination factor protein RarA 1684529 2863552 SAS1563 Staphylococcus aureus subsp. aureus MSSA476 recombination factor protein RarA YP_043681.1 1683255 D 282459 CDS YP_043682.1 49486461 2863544 complement(1684690..1685463) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1708; hypothetical protein 1685463 2863544 SAS1564 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043682.1 1684690 R 282459 CDS YP_043683.1 49486462 2863545 complement(1685677..1685778) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1709; hypothetical protein 1685778 2863545 SAS1565 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043683.1 1685677 R 282459 CDS YP_043684.1 49486463 2862967 complement(1685924..1687690) 1 NC_002953.3 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1687690 aspS 2862967 aspS Staphylococcus aureus subsp. aureus MSSA476 aspartyl-tRNA synthetase YP_043684.1 1685924 R 282459 CDS YP_043685.1 49486464 2862852 complement(1687706..1688968) 1 NC_002953.3 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1688968 hisS 2862852 hisS Staphylococcus aureus subsp. aureus MSSA476 histidyl-tRNA synthetase YP_043685.1 1687706 R 282459 CDS YP_043686.1 49486465 2862853 complement(1689429..1690304) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1712; N-acetylmuramoyl-L-alanine amidase 1690304 2862853 SAS1568 Staphylococcus aureus subsp. aureus MSSA476 N-acetylmuramoyl-L-alanine amidase YP_043686.1 1689429 R 282459 CDS YP_043687.1 49486466 2862968 complement(1690301..1690753) 1 NC_002953.3 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 1690753 2862968 SAS1569 Staphylococcus aureus subsp. aureus MSSA476 D-tyrosyl-tRNA(Tyr) deacylase YP_043687.1 1690301 R 282459 CDS YP_043688.1 49486467 2862969 complement(1690765..1692975) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1714; GTP pyrophosphokinase 1692975 2862969 SAS1570 Staphylococcus aureus subsp. aureus MSSA476 GTP pyrophosphokinase YP_043688.1 1690765 R 282459 CDS YP_043689.1 49486468 2864024 complement(1693382..1693900) 1 NC_002953.3 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1693900 2864024 SAS1571 Staphylococcus aureus subsp. aureus MSSA476 adenine phosphoribosyltransferase YP_043689.1 1693382 R 282459 CDS YP_043690.1 49486469 2864025 complement(1693922..1696195) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1716; single-stranded-DNA-specific exonuclease 1696195 2864025 SAS1572 Staphylococcus aureus subsp. aureus MSSA476 single-stranded-DNA-specific exonuclease YP_043690.1 1693922 R 282459 CDS YP_043691.1 49486470 2863005 complement(1696398..1698677) 1 NC_002953.3 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; bifunctional preprotein translocase subunit SecD/SecF 1698677 2863005 SAS1573 Staphylococcus aureus subsp. aureus MSSA476 bifunctional preprotein translocase subunit SecD/SecF YP_043691.1 1696398 R 282459 CDS YP_043692.1 49486471 2863006 complement(1698952..1699212) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1718; hypothetical protein 1699212 2863006 SAS1574 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043692.1 1698952 R 282459 CDS YP_043693.1 49486472 2862102 complement(1699231..1700370) 1 NC_002953.3 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1700370 tgt 2862102 tgt Staphylococcus aureus subsp. aureus MSSA476 queuine tRNA-ribosyltransferase YP_043693.1 1699231 R 282459 CDS YP_043694.1 49486473 2862994 complement(1700393..1701418) 1 NC_002953.3 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 1701418 queA 2862994 queA Staphylococcus aureus subsp. aureus MSSA476 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_043694.1 1700393 R 282459 CDS YP_043695.1 49486474 2862995 complement(1701420..1702424) 1 NC_002953.3 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1702424 ruvB 2862995 ruvB Staphylococcus aureus subsp. aureus MSSA476 Holliday junction DNA helicase RuvB YP_043695.1 1701420 R 282459 CDS YP_043696.1 49486475 2861830 complement(1702456..1703058) 1 NC_002953.3 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1703058 ruvA 2861830 ruvA Staphylococcus aureus subsp. aureus MSSA476 Holliday junction DNA helicase RuvA YP_043696.1 1702456 R 282459 CDS YP_043697.1 49486476 2862931 complement(1703072..1703530) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1723; hypothetical protein 1703530 2862931 SAS1579 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043697.1 1703072 R 282459 CDS YP_043698.1 49486477 2862115 complement(1703540..1704832) 1 NC_002953.3 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1704832 obgE 2862115 obgE Staphylococcus aureus subsp. aureus MSSA476 GTPase ObgE YP_043698.1 1703540 R 282459 CDS YP_043699.1 49486478 2862116 complement(1705317..1705601) 1 NC_002953.3 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1705601 rpmA 2862116 rpmA Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L27 YP_043699.1 1705317 R 282459 CDS YP_043700.1 49486479 2861746 complement(1705613..1705933) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1726; hypothetical protein 1705933 2861746 SAS1582 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043700.1 1705613 R 282459 CDS YP_043701.1 49486480 2861747 complement(1705939..1706247) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1727; 50S ribosomal protein L21 1706247 rplU 2861747 rplU Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L21 YP_043701.1 1705939 R 282459 CDS YP_043702.1 49486481 2864403 complement(1706609..1707139) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1728; hypothetical protein 1707139 2864403 SAS1584 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043702.1 1706609 R 282459 CDS YP_043703.1 49486482 2864374 complement(1707139..1707981) 1 NC_002953.3 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 1707981 2864374 SAS1585 Staphylococcus aureus subsp. aureus MSSA476 rod shape-determining protein MreC YP_043703.1 1707139 R 282459 CDS YP_043704.1 49486483 2864375 complement(1708180..1708299) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1729a; Doubtful CDS. No database matches; hypothetical protein 1708299 2864375 SAS1585a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043704.1 1708180 R 282459 CDS YP_043705.1 49486484 2861774 complement(1708373..1708846) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1730; hypothetical protein 1708846 2861774 SAS1586 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043705.1 1708373 R 282459 CDS YP_043706.1 49486485 2861775 1708988..1709203 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1731; hypothetical protein 1709203 2861775 SAS1587 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043706.1 1708988 D 282459 CDS YP_043707.1 49486486 2863993 complement(1709320..1709604) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1732; hypothetical protein 1709604 2863993 SAS1588 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043707.1 1709320 R 282459 CDS YP_043708.1 49486487 2863994 complement(1709672..1710358) 1 NC_002953.3 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1710358 radC 2863994 radC Staphylococcus aureus subsp. aureus MSSA476 DNA repair protein RadC YP_043708.1 1709672 R 282459 CDS YP_043709.1 49486488 2862698 complement(1710355..1711062) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1741; type III leader peptidase family protein 1711062 2862698 SAS1590 Staphylococcus aureus subsp. aureus MSSA476 type III leader peptidase family protein YP_043709.1 1710355 R 282459 CDS YP_043710.1 49486489 2862699 complement(1711332..1712603) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1742; folylpolyglutamate synthase 1712603 2862699 SAS1591 Staphylococcus aureus subsp. aureus MSSA476 folylpolyglutamate synthase YP_043710.1 1711332 R 282459 CDS YP_043711.1 49486490 2862868 complement(1712616..1715246) 1 NC_002953.3 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1715246 valS 2862868 valS Staphylococcus aureus subsp. aureus MSSA476 valyl-tRNA synthetase YP_043711.1 1712616 R 282459 CDS YP_043712.1 49486491 2864405 1715649..1716209 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1744; DNA-3-methyladenine glycosylase I 1716209 2864405 SAS1593 Staphylococcus aureus subsp. aureus MSSA476 DNA-3-methyladenine glycosylase I YP_043712.1 1715649 D 282459 CDS YP_043713.1 49486492 2864406 complement(1716432..1717505) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1745; hypothetical protein 1717505 2864406 SAS1594 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043713.1 1716432 R 282459 CDS YP_043714.1 49486493 2862775 complement(1717539..1717628) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1746; hypothetical protein 1717628 2862775 SAS1595 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043714.1 1717539 R 282459 CDS YP_043715.1 49486494 2862776 complement(1717701..1718987) 1 NC_002953.3 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 1718987 2862776 SAS1596 Staphylococcus aureus subsp. aureus MSSA476 glutamate-1-semialdehyde aminotransferase YP_043715.1 1717701 R 282459 CDS YP_043716.1 49486495 2862870 complement(1719035..1720009) 1 NC_002953.3 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 1720009 2862870 SAS1597 Staphylococcus aureus subsp. aureus MSSA476 delta-aminolevulinic acid dehydratase YP_043716.1 1719035 R 282459 CDS YP_043717.1 49486496 2862871 complement(1720012..1720680) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1749; uroporphyrinogen III synthase 1720680 2862871 SAS1598 Staphylococcus aureus subsp. aureus MSSA476 uroporphyrinogen III synthase YP_043717.1 1720012 R 282459 CDS YP_043718.1 49486497 2863981 complement(1720702..1721628) 1 NC_002953.3 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 1721628 hemC 2863981 hemC Staphylococcus aureus subsp. aureus MSSA476 porphobilinogen deaminase YP_043718.1 1720702 R 282459 CDS YP_043719.1 49486498 2863982 complement(1721670..1722485) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1751; hypothetical protein 1722485 2863982 SAS1600 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043719.1 1721670 R 282459 CDS YP_043720.1 49486499 2863285 complement(1722507..1723853) 1 NC_002953.3 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1723853 hemA 2863285 hemA Staphylococcus aureus subsp. aureus MSSA476 glutamyl-tRNA reductase YP_043720.1 1722507 R 282459 CDS YP_043721.1 49486500 2862777 complement(1724070..1724660) 1 NC_002953.3 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1724660 engB 2862777 engB Staphylococcus aureus subsp. aureus MSSA476 ribosome biogenesis GTP-binding protein YsxC YP_043721.1 1724070 R 282459 CDS YP_043722.1 49486501 2862778 complement(1724814..1726076) 1 NC_002953.3 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1726076 clpX 2862778 clpX Staphylococcus aureus subsp. aureus MSSA476 ATP-dependent protease ATP-binding subunit ClpX YP_043722.1 1724814 R 282459 CDS YP_043723.1 49486502 2862679 complement(1726227..1727528) 1 NC_002953.3 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1727528 tig 2862679 tig Staphylococcus aureus subsp. aureus MSSA476 trigger factor YP_043723.1 1726227 R 282459 CDS YP_043724.1 49486503 2862680 complement(1727691..1728620) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1756; hypothetical protein 1728620 2862680 SAS1605 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043724.1 1727691 R 282459 CDS YP_043725.1 49486504 2863272 complement(1728639..1729247) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1757; hypothetical protein 1729247 2863272 SAS1606 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043725.1 1728639 R 282459 CDS YP_043726.1 49486505 2863273 complement(1729389..1729745) 1 NC_002953.3 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1729745 rplT 2863273 rplT Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L20 YP_043726.1 1729389 R 282459 CDS YP_043727.1 49486506 2863302 complement(1729792..1729992) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1759; 50S ribosomal protein L35 1729992 rpmI 2863302 rpmI Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L35 YP_043727.1 1729792 R 282459 CDS YP_043728.1 49486507 2863303 complement(1730021..1730548) 1 NC_002953.3 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 1730548 infC 2863303 infC Staphylococcus aureus subsp. aureus MSSA476 translation initiation factor IF-3 YP_043728.1 1730021 R 282459 CDS YP_043729.1 49486508 2863301 complement(1730777..1732270) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1761; lysine-specific permease 1732270 2863301 SAS1610 Staphylococcus aureus subsp. aureus MSSA476 lysine-specific permease YP_043729.1 1730777 R 282459 CDS YP_043730.1 49486509 2862626 complement(1732696..1734633) 1 NC_002953.3 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1734633 thrS 2862626 thrS Staphylococcus aureus subsp. aureus MSSA476 threonyl-tRNA synthetase YP_043730.1 1732696 R 282459 CDS YP_043731.1 49486510 2862627 complement(1735045..1735965) 1 NC_002953.3 Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 1735965 2862627 SAS1612 Staphylococcus aureus subsp. aureus MSSA476 primosomal protein DnaI YP_043731.1 1735045 R 282459 CDS YP_043732.1 49486511 2863464 complement(1735965..1737365) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1764; chromosome replication initiation/membrane attachment protein 1737365 2863464 SAS1613 Staphylococcus aureus subsp. aureus MSSA476 chromosome replication initiation/membrane attachment protein YP_043732.1 1735965 R 282459 CDS YP_043733.1 49486512 2863465 complement(1737366..1737836) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1765; transcriptional regulator NrdR 1737836 nrdR 2863465 nrdR Staphylococcus aureus subsp. aureus MSSA476 transcriptional regulator NrdR YP_043733.1 1737366 R 282459 CDS YP_043734.1 49486513 2863482 complement(1738047..1739072) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1766; glyceraldehyde 3-phosphate dehydrogenase 2 1739072 2863482 SAS1615 Staphylococcus aureus subsp. aureus MSSA476 glyceraldehyde 3-phosphate dehydrogenase 2 YP_043734.1 1738047 R 282459 CDS YP_043735.1 49486514 2863483 complement(1739242..1739865) 1 NC_002953.3 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 1739865 coaE 2863483 coaE Staphylococcus aureus subsp. aureus MSSA476 dephospho-CoA kinase YP_043735.1 1739242 R 282459 CDS YP_043736.1 49486515 2863430 complement(1739881..1740753) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1768; formamidopyrimidine-DNA glycosylase 1740753 2863430 SAS1617 Staphylococcus aureus subsp. aureus MSSA476 formamidopyrimidine-DNA glycosylase YP_043736.1 1739881 R 282459 CDS YP_043737.1 49486516 2863431 complement(1740769..1743399) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1769; DNA polymerase I 1743399 2863431 SAS1618 Staphylococcus aureus subsp. aureus MSSA476 DNA polymerase I YP_043737.1 1740769 R 282459 CDS YP_043738.1 49486517 2863680 complement(1743693..1745180) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1770; hypothetical protein 1745180 2863680 SAS1619 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043738.1 1743693 R 282459 CDS YP_043739.1 49486518 2863675 complement(1745679..1747343) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1771; alkaline phosphatase synthesis sensor protein 1747343 2863675 SAS1620 Staphylococcus aureus subsp. aureus MSSA476 alkaline phosphatase synthesis sensor protein YP_043739.1 1745679 R 282459 CDS YP_043740.1 49486519 2863676 complement(1747340..1748044) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1772; alkaline phosphatase synthesis transcriptional regulatory protein 1748044 2863676 SAS1621 Staphylococcus aureus subsp. aureus MSSA476 alkaline phosphatase synthesis transcriptional regulatory protein YP_043740.1 1747340 R 282459 CDS YP_043741.1 49486520 2864056 complement(1748434..1749702) 1 NC_002953.3 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1749702 2864056 SAS1622 Staphylococcus aureus subsp. aureus MSSA476 isocitrate dehydrogenase YP_043741.1 1748434 R 282459 CDS YP_043742.1 49486521 2864057 complement(1749751..1750872) 1 NC_002953.3 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; citrate synthase 1750872 2864057 SAS1623 Staphylococcus aureus subsp. aureus MSSA476 citrate synthase YP_043742.1 1749751 R 282459 CDS YP_043743.1 49486522 2864075 1751220..1752581 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1775; D-serine/D-alanine/glycine transporter 1752581 2864075 SAS1624 Staphylococcus aureus subsp. aureus MSSA476 D-serine/D-alanine/glycine transporter YP_043743.1 1751220 D 282459 CDS YP_043744.1 49486523 2864076 complement(1752929..1754686) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1776; pyruvate kinase 1754686 2864076 SAS1625 Staphylococcus aureus subsp. aureus MSSA476 pyruvate kinase YP_043744.1 1752929 R 282459 CDS YP_043745.1 49486524 2863633 complement(1754708..1755676) 1 NC_002953.3 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 1755676 pfkA 2863633 pfkA Staphylococcus aureus subsp. aureus MSSA476 6-phosphofructokinase YP_043745.1 1754708 R 282459 CDS YP_043746.1 49486525 2863634 complement(1755945..1756889) 1 NC_002953.3 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1756889 2863634 SAS1627 Staphylococcus aureus subsp. aureus MSSA476 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_043746.1 1755945 R 282459 CDS YP_043747.1 49486526 2864099 complement(1756889..1757746) 1 NC_002953.3 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 1757746 2864099 SAS1628 Staphylococcus aureus subsp. aureus MSSA476 acetyl-CoA carboxylase subunit beta YP_043747.1 1756889 R 282459 CDS YP_043748.1 49486527 2863023 complement(1757941..1759170) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1780; NAD-dependent malic enzyme 1759170 2863023 SAS1629 Staphylococcus aureus subsp. aureus MSSA476 NAD-dependent malic enzyme YP_043748.1 1757941 R 282459 CDS YP_043749.1 49486528 2863024 complement(1759620..1762817) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1781; DNA polymerase III subunit alpha 1762817 2863024 SAS1630 Staphylococcus aureus subsp. aureus MSSA476 DNA polymerase III subunit alpha YP_043749.1 1759620 R 282459 CDS YP_043750.1 49486529 2864319 complement(1762838..1763779) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1782; hypothetical protein 1763779 2864319 SAS1631 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043750.1 1762838 R 282459 CDS YP_043751.1 49486530 2864320 complement(1764233..1765531) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1783; DNA-binding protein 1765531 2864320 SAS1632 Staphylococcus aureus subsp. aureus MSSA476 DNA-binding protein YP_043751.1 1764233 R 282459 CDS YP_043752.1 49486531 2862313 1765736..1766149 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1784; universal stress protein 1766149 2862313 SAS1633 Staphylococcus aureus subsp. aureus MSSA476 universal stress protein YP_043752.1 1765736 D 282459 CDS YP_043753.1 49486532 2862314 complement(1766454..1767143) 1 NC_002953.3 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins; metal-dependent hydrolase 1767143 2862314 SAS1634 Staphylococcus aureus subsp. aureus MSSA476 metal-dependent hydrolase YP_043753.1 1766454 R 282459 CDS YP_043754.1 49486533 2864118 1767318..1768373 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1786; metallopeptidase 1768373 2864118 SAS1635 Staphylococcus aureus subsp. aureus MSSA476 metallopeptidase YP_043754.1 1767318 D 282459 CDS YP_043755.1 49486534 2864119 complement(1768689..1769807) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1787; alanine dehydrogenase 1769807 2864119 SAS1636 Staphylococcus aureus subsp. aureus MSSA476 alanine dehydrogenase YP_043755.1 1768689 R 282459 CDS YP_043756.1 49486535 2864334 1769948..1770448 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1788; universal stress protein 1770448 2864334 SAS1637 Staphylococcus aureus subsp. aureus MSSA476 universal stress protein YP_043756.1 1769948 D 282459 CDS YP_043757.1 49486536 2861949 complement(1770694..1771896) 1 NC_002953.3 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 1771896 2861949 SAS1638 Staphylococcus aureus subsp. aureus MSSA476 acetate kinase YP_043757.1 1770694 R 282459 CDS YP_043758.1 49486537 2861950 complement(1771984..1772931) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1790; hypothetical protein 1772931 2861950 SAS1639 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043758.1 1771984 R 282459 CDS YP_043759.1 49486538 2861882 complement(1773054..1773548) 1 NC_002953.3 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1773548 tpx 2861882 tpx Staphylococcus aureus subsp. aureus MSSA476 thiol peroxidase YP_043759.1 1773054 R 282459 CDS YP_043760.1 49486539 2861883 complement(1773646..1774416) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1792; hypothetical protein 1774416 2861883 SAS1641 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043760.1 1773646 R 282459 CDS YP_043761.1 49486540 2864327 complement(1774460..1775683) 1 NC_002953.3 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 1775683 2864327 SAS1642 Staphylococcus aureus subsp. aureus MSSA476 thiamine biosynthesis protein ThiI YP_043761.1 1774460 R 282459 CDS YP_043762.1 49486541 2864328 complement(1775683..1776822) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1794; aminotransferase class-V protein 1776822 2864328 SAS1643 Staphylococcus aureus subsp. aureus MSSA476 aminotransferase class-V protein YP_043762.1 1775683 R 282459 CDS YP_043763.1 49486542 2861967 complement(1777194..1778888) 1 NC_002953.3 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 1778888 2861967 SAS1644 Staphylococcus aureus subsp. aureus MSSA476 septation ring formation regulator EzrA YP_043763.1 1777194 R 282459 CDS YP_043764.1 49486543 2861968 1779025..1779489 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1796; hypothetical protein 1779489 2861968 SAS1645 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043764.1 1779025 D 282459 CDS YP_043765.1 49486544 2864338 1779733..1780335 1 NC_002953.3 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 1780335 rpsD 2864338 rpsD Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S4 YP_043765.1 1779733 D 282459 CDS YP_043766.1 49486545 2861970 complement(1780551..1781294) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1798; hypothetical protein 1781294 2861970 SAS1647 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043766.1 1780551 R 282459 CDS YP_043767.1 49486546 2861971 1781374..1781820 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1799; OsmC-like protein 1781820 2861971 SAS1648 Staphylococcus aureus subsp. aureus MSSA476 OsmC-like protein YP_043767.1 1781374 D 282459 CDS YP_043768.1 49486547 2862024 1781934..1783094 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1800; soluble hydrogenase subunit 1783094 2862024 SAS1649 Staphylococcus aureus subsp. aureus MSSA476 soluble hydrogenase subunit YP_043768.1 1781934 D 282459 CDS YP_043769.1 49486548 2862025 1783081..1784685 1 NC_002953.3 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1784685 2862025 SAS1650 Staphylococcus aureus subsp. aureus MSSA476 D-3-phosphoglycerate dehydrogenase YP_043769.1 1783081 D 282459 CDS YP_043770.1 49486549 2861993 complement(1784835..1785965) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1802; hypothetical protein 1785965 2861993 SAS1651 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043770.1 1784835 R 282459 CDS YP_043771.1 49486550 2861994 complement(1786072..1787538) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1803; PTS system IIBC component 1787538 2861994 SAS1652 Staphylococcus aureus subsp. aureus MSSA476 PTS system IIBC component YP_043771.1 1786072 R 282459 CDS YP_043772.1 49486551 2862022 complement(1787666..1788283) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1804; acyltransferase 1788283 2862022 SAS1653 Staphylococcus aureus subsp. aureus MSSA476 acyltransferase YP_043772.1 1787666 R 282459 CDS YP_043773.1 49486552 2862023 1788455..1789729 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1805; protease 1789729 2862023 SAS1654 Staphylococcus aureus subsp. aureus MSSA476 protease YP_043773.1 1788455 D 282459 CDS YP_043774.1 49486553 2863706 complement(1789823..1791085) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1806; tyrosyl-tRNA synthetase 1791085 2863706 SAS1655 Staphylococcus aureus subsp. aureus MSSA476 tyrosyl-tRNA synthetase YP_043774.1 1789823 R 282459 CDS YP_043775.1 49486554 2863913 1791467..1792372 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1807; Possible gene remnant. Similar to the N-terminal region of Bacillus subtilis penicillin-binding protein 1A/1B PonA or BSU22320 SWALL:PBPA_BACSU (SWALL:P39793) (914 aa) fasta scores: E(): 9e-15, 31.86% id in 273 aa, and to Enterococcus faecalis penicillin-binding protein 1B, EF1740 SWALL:Q834C6 (EMBL:AE016952) (803 aa) fasta scores: E(): 1e-32, 37.5% id in 304 aa. Full length CDS is similar to Staphylococcus epidermidis SgtA protein SE1407 SWALL:Q8CNW0 (EMBL:AE016748) (301 aa) fasta scores: E(): 1.7e-69, 63.3% id in 297 aa; transglycosylase 1792372 2863913 SAS1656 Staphylococcus aureus subsp. aureus MSSA476 transglycosylase YP_043775.1 1791467 D 282459 CDS YP_043776.1 49486555 2863914 complement(1792575..1795262) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1809; haptoglobin-binding surface anchored protein 1795262 2863914 SAS1657 Staphylococcus aureus subsp. aureus MSSA476 haptoglobin-binding surface anchored protein YP_043776.1 1792575 R 282459 CDS YP_043777.1 49486556 2862376 1795255..1795350 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1809a; Doubtful CDS; hypothetical protein 1795350 2862376 SAS1657a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043777.1 1795255 D 282459 CDS YP_043778.1 49486557 2862377 complement(1795596..1797263) 1 NC_002953.3 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 1797263 2862377 SAS1658 Staphylococcus aureus subsp. aureus MSSA476 formate--tetrahydrofolate ligase YP_043778.1 1795596 R 282459 CDS YP_043779.1 49486558 2863609 complement(1797703..1799409) 1 NC_002953.3 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 1799409 2863609 SAS1659 Staphylococcus aureus subsp. aureus MSSA476 acetyl-CoA synthetase YP_043779.1 1797703 R 282459 CDS YP_043780.1 49486559 2863610 1799578..1800210 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1812; acetoin utilization protein 1800210 2863610 SAS1660 Staphylococcus aureus subsp. aureus MSSA476 acetoin utilization protein YP_043780.1 1799578 D 282459 CDS YP_043781.1 49486560 2862717 1800235..1801404 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1813; histone deacetylase family protein 1801404 2862717 SAS1661 Staphylococcus aureus subsp. aureus MSSA476 histone deacetylase family protein YP_043781.1 1800235 D 282459 CDS YP_043782.1 49486561 2862718 complement(1801502..1802491) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1814; catabolite control protein A 1802491 2862718 SAS1662 Staphylococcus aureus subsp. aureus MSSA476 catabolite control protein A YP_043782.1 1801502 R 282459 CDS YP_043783.1 49486562 2862368 complement(1803031..1804122) 1 NC_002953.3 catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate; bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase 1804122 2862368 SAS1663 Staphylococcus aureus subsp. aureus MSSA476 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase YP_043783.1 1803031 R 282459 CDS YP_043784.1 49486563 2863230 complement(1804822..1805868) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1816; hypothetical protein 1805868 2863230 SAS1664 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043784.1 1804822 R 282459 CDS YP_043785.1 49486564 2863231 complement(1805942..1806433) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1817; hypothetical protein 1806433 2863231 SAS1665 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043785.1 1805942 R 282459 CDS YP_043786.1 49486565 2862902 complement(1806507..1807820) 1 NC_002953.3 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1807820 murC 2862902 murC Staphylococcus aureus subsp. aureus MSSA476 UDP-N-acetylmuramate--L-alanine ligase YP_043786.1 1806507 R 282459 CDS YP_043787.1 49486566 2862903 complement(1807844..1811668) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1819; FtsK/SpoIIIE family protein 1811668 2862903 SAS1667 Staphylococcus aureus subsp. aureus MSSA476 FtsK/SpoIIIE family protein YP_043787.1 1807844 R 282459 CDS YP_043788.1 49486567 2862904 complement(1811689..1812285) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1820; hypothetical protein 1812285 2862904 SAS1668 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043788.1 1811689 R 282459 CDS YP_043789.1 49486568 2862905 complement(1812314..1813171) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1821; hypothetical protein 1813171 2862905 SAS1669 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043789.1 1812314 R 282459 CDS YP_043790.1 49486569 2862382 complement(1813271..1813582) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1822; thioredoxin 1813582 2862382 SAS1670 Staphylococcus aureus subsp. aureus MSSA476 thioredoxin YP_043790.1 1813271 R 282459 CDS YP_043791.1 49486570 2862383 complement(1813647..1814723) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1823; aminopeptidase 1814723 2862383 SAS1671 Staphylococcus aureus subsp. aureus MSSA476 aminopeptidase YP_043791.1 1813647 R 282459 CDS YP_043792.1 49486571 2862373 1814810..1815121 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1824; hypothetical protein 1815121 2862373 SAS1672 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043792.1 1814810 D 282459 CDS YP_043793.1 49486572 2862378 complement(1815246..1816088) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1825; metallo-beta-lactamase superfamily protein 1816088 2862378 SAS1673 Staphylococcus aureus subsp. aureus MSSA476 metallo-beta-lactamase superfamily protein YP_043793.1 1815246 R 282459 CDS YP_043794.1 49486573 2862379 complement(1816558..1817202) 1 NC_002953.3 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 1817202 trmB 2862379 trmB Staphylococcus aureus subsp. aureus MSSA476 tRNA (guanine-N(7)-)-methyltransferase YP_043794.1 1816558 R 282459 CDS YP_043795.1 49486574 2863805 complement(1817217..1818008) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1834; hypothetical protein 1818008 2863805 SAS1675 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043795.1 1817217 R 282459 CDS YP_043796.1 49486575 2863806 complement(1818559..1819407) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1835; D-alanine aminotransferase 1819407 2863806 SAS1676 Staphylococcus aureus subsp. aureus MSSA476 D-alanine aminotransferase YP_043796.1 1818559 R 282459 CDS YP_043797.1 49486576 2862528 complement(1819411..1820820) 1 NC_002953.3 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 1820820 2862528 SAS1677 Staphylococcus aureus subsp. aureus MSSA476 dipeptidase PepV YP_043797.1 1819411 R 282459 CDS YP_043798.1 49486577 2862529 complement(1821513..1821935) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1837; hypothetical protein 1821935 2862529 SAS1678 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043798.1 1821513 R 282459 CDS YP_043799.1 49486578 2862805 complement(1821952..1822647) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1838; RNA pseudouridine synthase 1822647 2862805 SAS1679 Staphylococcus aureus subsp. aureus MSSA476 RNA pseudouridine synthase YP_043799.1 1821952 R 282459 CDS YP_043800.1 49486579 2862806 complement(1822644..1824305) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1839; polysaccharide biosynthesis protein 1824305 2862806 SAS1680 Staphylococcus aureus subsp. aureus MSSA476 polysaccharide biosynthesis protein YP_043800.1 1822644 R 282459 CDS YP_043801.1 49486580 2862794 1824712..1825980 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1840; hypothetical protein 1825980 2862794 SAS1681 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043801.1 1824712 D 282459 CDS YP_043802.1 49486581 2862512 complement(1826097..1832657) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1841; surface anchored protein 1832657 2862512 SAS1682 Staphylococcus aureus subsp. aureus MSSA476 surface anchored protein YP_043802.1 1826097 R 282459 CDS YP_043803.1 49486582 2862513 complement(1832983..1833294) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1842; hypothetical protein 1833294 2862513 SAS1683 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043803.1 1832983 R 282459 CDS YP_043804.1 49486583 2862510 complement(1833316..1835736) 1 NC_002953.3 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1835736 leuS 2862510 leuS Staphylococcus aureus subsp. aureus MSSA476 leucyl-tRNA synthetase YP_043804.1 1833316 R 282459 CDS YP_043805.1 49486584 2862511 complement(1836027..1837208) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1844; hypothetical protein 1837208 2862511 SAS1685 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043805.1 1836027 R 282459 CDS YP_043806.1 49486585 2862508 1837318..1838271 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1845; hypothetical protein 1838271 2862508 SAS1686 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043806.1 1837318 D 282459 CDS YP_043807.1 49486586 2862509 1838268..1838831 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1846; hypothetical protein 1838831 2862509 SAS1687 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043807.1 1838268 D 282459 CDS YP_043808.1 49486587 2863619 complement(1838951..1839451) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1847; repressor of toxins 1839451 2863619 SAS1688 Staphylococcus aureus subsp. aureus MSSA476 repressor of toxins YP_043808.1 1838951 R 282459 CDS YP_043809.1 49486588 2863620 complement(1839926..1840753) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1848; hypothetical protein 1840753 2863620 SAS1689 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043809.1 1839926 R 282459 CDS YP_043810.1 49486589 2863402 1840987..1841988 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1849; proline dehydrogenase 1841988 2863402 SAS1690 Staphylococcus aureus subsp. aureus MSSA476 proline dehydrogenase YP_043810.1 1840987 D 282459 CDS YP_043811.1 49486590 2863391 complement(1842110..1842574) 1 NC_002953.3 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 1842574 ribH 2863391 ribH Staphylococcus aureus subsp. aureus MSSA476 6,7-dimethyl-8-ribityllumazine synthase YP_043811.1 1842110 R 282459 CDS YP_043812.1 49486591 2863392 complement(1842587..1843768) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1851; riboflavin biosynthesis protein 1843768 2863392 SAS1692 Staphylococcus aureus subsp. aureus MSSA476 riboflavin biosynthesis protein YP_043812.1 1842587 R 282459 CDS YP_043813.1 49486592 2863387 complement(1843779..1844411) 1 NC_002953.3 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1844411 2863387 SAS1693 Staphylococcus aureus subsp. aureus MSSA476 riboflavin synthase subunit alpha YP_043813.1 1843779 R 282459 CDS YP_043814.1 49486593 2863388 complement(1844418..1845461) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1853; bifunctional riboflavin biosynthesis protein 1845461 2863388 SAS1694 Staphylococcus aureus subsp. aureus MSSA476 bifunctional riboflavin biosynthesis protein YP_043814.1 1844418 R 282459 CDS YP_043815.1 49486594 2864359 complement(1845942..1847444) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1854; hypothetical protein 1847444 2864359 SAS1695 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043815.1 1845942 R 282459 CDS YP_043816.1 49486595 2864360 1847967..1848281 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1855; arsenical resistance operon repressor 2 1848281 2864360 SAS1696 Staphylococcus aureus subsp. aureus MSSA476 arsenical resistance operon repressor 2 YP_043816.1 1847967 D 282459 CDS YP_043817.1 49486596 2862340 1848281..1849573 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1856; arsenical pump membrane protein 2 1849573 2862340 SAS1697 Staphylococcus aureus subsp. aureus MSSA476 arsenical pump membrane protein 2 YP_043817.1 1848281 D 282459 CDS YP_043818.1 49486597 2862341 complement(1849660..1850514) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1857; hypothetical protein 1850514 2862341 SAS1698 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043818.1 1849660 R 282459 CDS YP_043819.1 49486598 2862328 complement(1850790..1851014) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1858; hypothetical protein 1851014 2862328 SAS1699 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043819.1 1850790 R 282459 CDS YP_043820.1 49486599 2861925 1851213..1851683 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1859; DNA-binding protein 1851683 2861925 SAS1700 Staphylococcus aureus subsp. aureus MSSA476 DNA-binding protein YP_043820.1 1851213 D 282459 CDS YP_043821.1 49486600 2861926 1851796..1852239 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1860; hypothetical protein 1852239 2861926 SAS1701 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043821.1 1851796 D 282459 CDS YP_043822.1 49486601 2861908 complement(1852226..1852669) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1861; hypothetical protein 1852669 2861908 SAS1702 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043822.1 1852226 R 282459 CDS YP_043823.1 49486602 2864254 complement(1854039..1854752) 1 NC_002953.3 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase 1854752 2864254 SAS1704 Staphylococcus aureus subsp. aureus MSSA476 translaldolase YP_043823.1 1854039 R 282459 CDS YP_043824.1 49486603 2864255 1855012..1855314 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1865; hypothetical protein 1855314 2864255 SAS1705 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043824.1 1855012 D 282459 CDS YP_043825.1 49486604 2863178 1855492..1855935 1 NC_002953.3 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1855935 2863178 SAS1706 Staphylococcus aureus subsp. aureus MSSA476 camphor resistance protein CrcB YP_043825.1 1855492 D 282459 CDS YP_043826.1 49486605 2863179 1855932..1856285 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1867; CrcB-like protein 1856285 2863179 SAS1707 Staphylococcus aureus subsp. aureus MSSA476 CrcB-like protein YP_043826.1 1855932 D 282459 CDS YP_043827.1 49486606 2862067 1856477..1856656 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0402; Doubtful CDS. No significant database matches; hypothetical protein 1856656 2862067 SAS1708 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043827.1 1856477 D 282459 CDS YP_043828.1 49486607 2862147 complement(1856668..1857501) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1868; aldo/keto reductase 1857501 2862147 SAS1709 Staphylococcus aureus subsp. aureus MSSA476 aldo/keto reductase YP_043828.1 1856668 R 282459 CDS YP_043829.1 49486608 2862148 complement(1857713..1858624) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1869; hypothetical protein 1858624 2862148 SAS1710 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043829.1 1857713 R 282459 CDS YP_043830.1 49486609 2863198 complement(1858746..1859939) 1 NC_002953.3 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1859939 2863198 SAS1711 Staphylococcus aureus subsp. aureus MSSA476 S-adenosylmethionine synthetase YP_043830.1 1858746 R 282459 CDS YP_043831.1 49486610 2863199 1860311..1861903 1 NC_002953.3 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 1861903 2863199 SAS1712 Staphylococcus aureus subsp. aureus MSSA476 phosphoenolpyruvate carboxykinase YP_043831.1 1860311 D 282459 CDS YP_043832.1 49486611 2863115 1862027..1862203 1 NC_002953.3 Doubtful CDS. No database matches; hypothetical protein 1862203 2863115 SAS1712a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043832.1 1862027 D 282459 CDS YP_043833.1 49486612 2863116 complement(1862281..1863051) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1873; hypothetical protein 1863051 2863116 SAS1713 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043833.1 1862281 R 282459 CDS YP_043834.1 49486613 2862088 complement(1863032..1863511) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1874; hypothetical protein 1863511 2862088 SAS1714 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043834.1 1863032 R 282459 CDS YP_043835.1 49486614 2862089 1863571..1863828 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1875; hypothetical protein 1863828 2862089 SAS1715 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043835.1 1863571 D 282459 CDS YP_043836.1 49486615 2862166 complement(1863825..1864826) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1876; hypothetical protein 1864826 2862166 SAS1716 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043836.1 1863825 R 282459 CDS YP_043837.1 49486616 2862486 complement(1864831..1866309) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1877; AMP-binding protein 1866309 2862486 SAS1717 Staphylococcus aureus subsp. aureus MSSA476 AMP-binding protein YP_043837.1 1864831 R 282459 CDS YP_043838.1 49486617 2862487 complement(1866468..1866950) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1878; lipoprotein 1866950 2862487 SAS1718 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_043838.1 1866468 R 282459 CDS YP_043839.1 49486618 2863205 1867262..1867876 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1879; hypothetical protein 1867876 2863205 SAS1719 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043839.1 1867262 D 282459 CDS YP_043840.1 49486619 2863206 1867957..1868952 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1880; hypothetical protein 1868952 2863206 SAS1720 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043840.1 1867957 D 282459 CDS YP_043841.1 49486620 2863592 1869026..1869652 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1881; lipoprotein 1869652 2863592 SAS1721 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_043841.1 1869026 D 282459 CDS YP_043842.1 49486621 2863593 1869693..1870034 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1882; hypothetical protein 1870034 2863593 SAS1722 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043842.1 1869693 D 282459 CDS YP_043843.1 49486622 2863156 1870135..1870707 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1883; hypothetical protein 1870707 2863156 SAS1723 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043843.1 1870135 D 282459 CDS YP_043844.1 49486623 2863157 complement(1870995..1871462) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1885; CDS is truncated at the C-terminus in comparison to SAR1885; hypothetical protein 1871462 2863157 SAS1724 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043844.1 1870995 R 282459 CDS YP_043845.1 49486624 2863117 complement(1871836..1872012) 1 NC_002953.3 Poor database matches. Similar to an internal region of Lactococcus lactis hypothetical lactococcin 972 immunity protein LclB SWALL:Q9L651 (EMBL:AF242367) (648 aa) fasta scores: E(): 0.94, 34.54% id in 55 aa. Possible gene remnant; hypothetical protein 1872012 2863117 SAS1725 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043845.1 1871836 R 282459 CDS YP_043846.1 49486625 2862190 complement(1872023..1872406) 1 NC_002953.3 hypothetical protein 1872406 2862190 SAS1726 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043846.1 1872023 R 282459 CDS YP_043847.1 49486626 2863557 complement(1879882..1881081) 1 NC_002953.3 restriction modification DNA specificity protein 1881081 2863557 SAS1731 Staphylococcus aureus subsp. aureus MSSA476 restriction modification DNA specificity protein YP_043847.1 1879882 R 282459 CDS YP_043848.1 49486627 2862938 complement(1881074..1882630) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0433; type I restriction enzyme modification protein 1882630 2862938 SAS1732 Staphylococcus aureus subsp. aureus MSSA476 type I restriction enzyme modification protein YP_043848.1 1881074 R 282459 CDS YP_043849.1 49486628 2862939 complement(1882993..1883712) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1900; serine protease 1883712 2862939 SAS1733 Staphylococcus aureus subsp. aureus MSSA476 serine protease YP_043849.1 1882993 R 282459 CDS YP_043850.1 49486629 2861945 complement(1883833..1884552) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1906; serine protease 1884552 2861945 SAS1734 Staphylococcus aureus subsp. aureus MSSA476 serine protease YP_043850.1 1883833 R 282459 CDS YP_043851.1 49486630 2863580 complement(1884610..1885332) 1 NC_002953.3 C-terminus is similar to the C-terminal regions of Staphylococcus aureus exfoliative toxin A precursor Eta SWALL:ETA_STAAU (SWALL:P09331) (280 aa) fasta scores: E(): 2.3e-11, 32.7% id in 211 aa, and to Staphylococcus hyicus exfoliative toxin B SWALL:Q9KWH0 (EMBL:AB036767) (268 aa) fasta scores: E(): 8.7e-09, 32.65% id in 196 aa; serine protease 1885332 2863580 SAS1735 Staphylococcus aureus subsp. aureus MSSA476 serine protease YP_043851.1 1884610 R 282459 CDS YP_043852.1 49486631 2863581 complement(1885457..1886164) 1 NC_002953.3 Similar to Staphylococcus aureus exfoliative toxin B precursor Etb SWALL:ETB_STAAU (SWALL:P09332) (277 aa) fasta scores: E(): 1.9e-06, 32.88% id in 225 aa; serine protease 1886164 2863581 SAS1736 Staphylococcus aureus subsp. aureus MSSA476 serine protease YP_043852.1 1885457 R 282459 CDS YP_043853.1 49486632 2864036 complement(1886600..1886818) 1 NC_002953.3 hypothetical protein 1886818 2864036 SAS1737 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043853.1 1886600 R 282459 CDS YP_043854.1 49486633 2864037 1887128..1887694 1 NC_002953.3 Similar to Staphylococcus aureus pathogenicity island 3 Ear protein SWALL:Q93CE4 (EMBL:AF410775) (185 aa) fasta scores: E(): 2.8e-19, 42.1% id in 190 aa; hypothetical protein 1887694 2864037 SAS1738 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043854.1 1887128 D 282459 CDS YP_043855.1 49486634 2863987 complement(1888168..1888878) 1 NC_002953.3 Similar to Staphylococcus epidermidis ABC transporter subunit EpiG SWALL:Q54004 (EMBL:U77778) (230 aa) fasta scores: E(): 7.1e-42, 49.34% id in 229 aa, and to Streptococcus mutans MutG protein smu.657 SWALL:Q8DV51 (EMBL:AE014909) (248 aa) fasta scores: E(): 0.00014, 22.67% id in 247 aa; lantibiotic ABC transporter protein 1888878 2863987 SAS1739 Staphylococcus aureus subsp. aureus MSSA476 lantibiotic ABC transporter protein YP_043855.1 1888168 R 282459 CDS YP_043856.1 49486635 2863988 complement(1888863..1889624) 1 NC_002953.3 Similar to Staphylococcus epidermidis ABC transporter subunit EpiE SWALL:Q54003 (EMBL:U77778) (254 aa) fasta scores: E(): 6.6e-51, 51.19% id in 252 aa, and to Bacillus subtilis Spa E SWALL:Q93GH0 (EMBL:AF233755) (251 aa) fasta scores: E(): 2.8e-11, 22.85% id in 245 aa; lantibiotic ABC transporter protein 1889624 2863988 SAS1740 Staphylococcus aureus subsp. aureus MSSA476 lantibiotic ABC transporter protein YP_043856.1 1888863 R 282459 CDS YP_043857.1 49486636 2863354 complement(1889621..1890313) 1 NC_002953.3 Similar to Streptococcus pyogenes lantibiotic transport ATP-binding protein SrtF or spy1085 SWALL:SRTF_STRPY (SWALL:Q9FDU7) (229 aa) fasta scores: E(): 1.3e-32, 48.85% id in 219 aa, and to Staphylococcus epidermidis ABC transporter subunit EpiF SWALL:Q54002 (EMBL:U77778) (231 aa) fasta scores: E(): 2.2e-54, 72.88% id in 225 aa; lantibiotic transport ATP-binding protein 1890313 2863354 SAS1741 Staphylococcus aureus subsp. aureus MSSA476 lantibiotic transport ATP-binding protein YP_043857.1 1889621 R 282459 CDS YP_043858.1 49486637 2863355 complement(1890336..1891709) 1 NC_002953.3 Similar to Staphylococcus epidermidis epidermin leader peptide processing serine protease EpiP precursor epiP SWALL:EPIP_STAEP (SWALL:P30199) (461 aa) fasta scores: E(): 3.1e-77, 49.24% id in 461 aa, and to an internal region of Lactococcus lactis nisin leader peptide processing serine protease precursor NisP SWALL:NISP_LACLA (SWALL:Q07596) (682 aa) fasta scores: E(): 3.7e-46, 36.52% id in 449 aa; lantibiotic leader peptide processing serine protease 1891709 2863355 SAS1742 Staphylococcus aureus subsp. aureus MSSA476 lantibiotic leader peptide processing serine protease YP_043858.1 1890336 R 282459 CDS YP_043859.1 49486638 2864015 complement(1891719..1892252) 1 NC_002953.3 Similar to Staphylococcus epidermidis epidermin modifying enzyme EpiD SWALL:EPID_STAEP (SWALL:P30197) (181 aa) fasta scores: E(): 2.5e-36, 53.48% id in 172 aa, and to Streptococcus mutans MutD protein SWALL:Q9RPL6 (EMBL:AF154675) (188 aa) fasta scores: E(): 1.2e-17, 39.02% id in 164 aa; lantibiotic modifying enzyme 1892252 2864015 SAS1743 Staphylococcus aureus subsp. aureus MSSA476 lantibiotic modifying enzyme YP_043859.1 1891719 R 282459 CDS YP_043860.1 49486639 2862747 complement(1892253..1893497) 1 NC_002953.3 Similar to Staphylococcus epidermidis epidermin biosynthesis protein EpiC SWALL:EPIC_STAEP (SWALL:P30196) (455 aa) fasta scores: E(): 1.8e-70, 46.71% id in 411 aa, and to Streptococcus mutans MutC protein SWALL:Q9RPL7 (EMBL:AF154675) (424 aa) fasta scores: E(): 1.2e-38, 32.47% id in 425 aa; lantibiotic biosynthesis protein 1893497 2862747 SAS1744 Staphylococcus aureus subsp. aureus MSSA476 lantibiotic biosynthesis protein YP_043860.1 1892253 R 282459 CDS YP_043861.1 49486640 2862748 complement(1893490..1896483) 1 NC_002953.3 Similar to Staphylococcus epidermidis epidermin biosynthesis protein EpiB SWALL:EPIB_STAEP (SWALL:P30195) (986 aa) fasta scores: E(): 3.1e-127, 45.08% id in 996 aa, and to Bacillus subtilis subtilin biosynthesis protein SpaB or SpaD or spaE SWALL:SPAB_BACSU (SWALL:P39774) (1030 aa) fasta scores: E(): 2.8e-43, 25.95% id in 1044 aa; lantibiotic biosynthesis protein 1896483 2862748 SAS1745 Staphylococcus aureus subsp. aureus MSSA476 lantibiotic biosynthesis protein YP_043861.1 1893490 R 282459 CDS YP_043862.1 49486641 2864010 complement(1896548..1896691) 1 NC_002953.3 Similar to Staphylococcus gallinarum lantibiotic gallidermin precursor GdmA SWALL:LANG_STAGA (SWALL:P21838) (52 aa) fasta scores: E(): 1.7e-09, 64.44% id in 45 aa, and to Staphylococcus epidermidis lantibiotic epidermin precursor EpiA SWALL:LANE_STAEP (SWALL:P08136) (52 aa) fasta scores: E(): 1.1e-08, 61.36% id in 44 aa; lantibiotic protein 1896691 2864010 SAS1746 Staphylococcus aureus subsp. aureus MSSA476 lantibiotic protein YP_043862.1 1896548 R 282459 CDS YP_043863.1 49486642 2864011 complement(1897428..1897571) 1 NC_002953.3 Similar to Staphylococcus gallinarum lantibiotic gallidermin precursor GdmA SWALL:LANG_STAGA (SWALL:P21838) (52 aa) fasta scores: E(): 3.1e-07, 51.11% id in 45 aa, and to Staphylococcus epidermidis lantibiotic epidermin precursor EpiA SWALL:LANE_STAEP (SWALL:P08136) (52 aa) fasta scores: E(): 1.4e-06, 50% id in 44 aa; lantibiotic protein 1897571 2864011 SAS1747a Staphylococcus aureus subsp. aureus MSSA476 lantibiotic protein YP_043863.1 1897428 R 282459 CDS YP_043864.1 49486643 2864425 complement(1897813..1898796) 1 NC_002953.3 Similar to Staphylococcus aureus gamma-hemolysin component B precursor HlgB SWALL:HLGB_STAAN (SWALL:Q07226) (325 aa) fasta scores: E(): 9.7e-96, 75.92% id in 324 aa; gamma-hemolysin component B precursor 1898796 hlgB 2864425 hlgB Staphylococcus aureus subsp. aureus MSSA476 gamma-hemolysin component B precursor YP_043864.1 1897813 R 282459 CDS YP_043865.1 49486644 2864424 complement(1898798..1899733) 1 NC_002953.3 Similar to Staphylococcus aureus gamma-hemolysin component A precursor HlgA or Hlg2 SWALL:HLGA_STAAM (SWALL:P31714) (309 aa) fasta scores: E(): 5.4e-84, 70.87% id in 309 aa; gamma-hemolysin component A precursor 1899733 hlgA 2864424 hlgA Staphylococcus aureus subsp. aureus MSSA476 gamma-hemolysin component A precursor YP_043865.1 1898798 R 282459 CDS YP_043866.1 49486645 2863983 1900630..1901085 1 NC_002953.3 hypothetical protein 1901085 2863983 SAS1750 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043866.1 1900630 D 282459 CDS YP_043867.1 49486646 2863984 1901098..1901886 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1914; Poor database matches. Weakly similar to the N-terminal region of Plasmodium falciparum hypothetical protein PF11_0387 SWALL:Q8IHY9 (EMBL:AE014841) (551 aa) fasta scores: E(): 1, 23.89% id in 272 aa; hypothetical protein 1901886 2863984 SAS1751 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043867.1 1901098 D 282459 CDS YP_043868.1 49486647 2862762 complement(1904343..1904897) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1922; hypothetical protein 1904897 2862762 SAS1752 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043868.1 1904343 R 282459 CDS YP_043869.1 49486648 2862763 complement(1905219..1906619) 1 NC_002953.3 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX; protoporphyrinogen oxidase 1906619 2862763 SAS1753 Staphylococcus aureus subsp. aureus MSSA476 protoporphyrinogen oxidase YP_043869.1 1905219 R 282459 CDS YP_043870.1 49486649 2862674 complement(1906643..1907566) 1 NC_002953.3 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1907566 hemH 2862674 hemH Staphylococcus aureus subsp. aureus MSSA476 ferrochelatase YP_043870.1 1906643 R 282459 CDS YP_043871.1 49486650 2863287 complement(1907624..1908661) 1 NC_002953.3 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 1908661 hemE 2863287 hemE Staphylococcus aureus subsp. aureus MSSA476 uroporphyrinogen decarboxylase YP_043871.1 1907624 R 282459 CDS YP_043872.1 49486651 2863288 1908924..1909427 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1926; signal transduction protein 1909427 2863288 SAS1756 Staphylococcus aureus subsp. aureus MSSA476 signal transduction protein YP_043872.1 1908924 D 282459 CDS YP_043873.1 49486652 2862618 complement(1909551..1910774) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1927; transporter protein 1910774 2862618 SAS1757 Staphylococcus aureus subsp. aureus MSSA476 transporter protein YP_043873.1 1909551 R 282459 CDS YP_043874.1 49486653 2862619 complement(1910767..1911507) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1928; ABC transporter ATP-binding protein 1911507 2862619 SAS1758 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_043874.1 1910767 R 282459 CDS YP_043875.1 49486654 2862665 1911641..1912063 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1929; HIT-family protein 1912063 2862665 SAS1759 Staphylococcus aureus subsp. aureus MSSA476 HIT-family protein YP_043875.1 1911641 D 282459 CDS YP_043876.1 49486655 2862666 1912205..1912570 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1930; hypothetical protein 1912570 2862666 SAS1760 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043876.1 1912205 D 282459 CDS YP_043877.1 49486656 2862641 1912548..1912754 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1930a; Similar to the N-terminal regions of Clostridium acetobutylicum hypothetical protein CAC0828 cac0828 SWALL:Q97KT8 (EMBL:AE007598) (308 aa) fasta scores: E(): 2, 32.3% id in 65 aa. Weakly similar to the N-terminal region of Clostridium tetani hypothetical protein ctp43 SWALL:Q899X2 (EMBL:AF528097) (142 aa) fasta scores: E(): 7, 23.63% id in 55 aa; hypothetical protein 1912754 2862641 SAS1760a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043877.1 1912548 D 282459 CDS YP_043878.1 49486657 2862642 1913303..1913860 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1931; hypothetical protein 1913860 2862642 SAS1761 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043878.1 1913303 D 282459 CDS YP_043879.1 49486658 2862667 1914065..1915027 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1932; peptidyl-prolyl cis-isomerase 1915027 2862667 SAS1762 Staphylococcus aureus subsp. aureus MSSA476 peptidyl-prolyl cis-isomerase YP_043879.1 1914065 D 282459 CDS YP_043880.1 49486659 2863421 complement(1915148..1916089) 1 NC_002953.3 catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates; 3'-5' exoribonuclease 1916089 2863421 SAS1763 Staphylococcus aureus subsp. aureus MSSA476 3'-5' exoribonuclease YP_043880.1 1915148 R 282459 CDS YP_043881.1 49486660 2863422 complement(1916086..1919022) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1934; hypothetical protein 1919022 2863422 SAS1764 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043881.1 1916086 R 282459 CDS YP_043882.1 49486661 2863228 complement(1919012..1920208) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1935; DNA repair exonuclease 1920208 2863228 SAS1765 Staphylococcus aureus subsp. aureus MSSA476 DNA repair exonuclease YP_043882.1 1919012 R 282459 CDS YP_043883.1 49486662 2863229 complement(1921090..1921434) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1936; hypothetical protein 1921434 2863229 SAS1766 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043883.1 1921090 R 282459 CDS YP_043884.1 49486663 2863425 complement(1921503..1922627) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1937; hypothetical protein 1922627 2863425 SAS1767 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043884.1 1921503 R 282459 CDS YP_043885.1 49486664 2863426 complement(1922806..1923270) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1938; DNA-binding protein 1923270 2863426 SAS1768 Staphylococcus aureus subsp. aureus MSSA476 DNA-binding protein YP_043885.1 1922806 R 282459 CDS YP_043886.1 49486665 2863041 complement(1923626..1924249) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1939; response regulator 1924249 2863041 SAS1769 Staphylococcus aureus subsp. aureus MSSA476 response regulator YP_043886.1 1923626 R 282459 CDS YP_043887.1 49486666 2863042 complement(1924271..1925383) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1940; histidine kinase 1925383 2863042 SAS1770 Staphylococcus aureus subsp. aureus MSSA476 histidine kinase YP_043887.1 1924271 R 282459 CDS YP_043888.1 49486667 2863053 1925546..1926367 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1941; RNA pseudouridylate synthase 1926367 2863053 SAS1771 Staphylococcus aureus subsp. aureus MSSA476 RNA pseudouridylate synthase YP_043888.1 1925546 D 282459 CDS YP_043889.1 49486668 2863681 complement(1926828..1928213) 1 NC_002953.3 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1928213 fumC 2863681 fumC Staphylococcus aureus subsp. aureus MSSA476 fumarate hydratase YP_043889.1 1926828 R 282459 CDS YP_043890.1 49486669 2863682 complement(1928409..1928804) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1943; hypothetical protein 1928804 2863682 SAS1773 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043890.1 1928409 R 282459 CDS YP_043891.1 49486670 2861831 1928923..1929075 1 NC_002953.3 Doubtful CDS. No significant database matches; hypothetical protein 1929075 2861831 SAS1774 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043891.1 1928923 D 282459 CDS YP_043892.1 49486671 2864281 1929082..1929345 1 NC_002953.3 hypothetical protein 1929345 2864281 SAS1775 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043892.1 1929082 D 282459 CDS YP_043893.1 49486672 2863641 complement(1929410..1929562) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1944; hypothetical protein 1929562 2863641 SAS1776 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043893.1 1929410 R 282459 CDS YP_043894.1 49486673 2863642 complement(1929587..1930186) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1945; hypothetical protein 1930186 2863642 SAS1777 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043894.1 1929587 R 282459 CDS YP_043895.1 49486674 2864192 complement(1930345..1930815) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1946; SpoU rRNA methylase family protein 1930815 2864192 SAS1778 Staphylococcus aureus subsp. aureus MSSA476 SpoU rRNA methylase family protein YP_043895.1 1930345 R 282459 CDS YP_043896.1 49486675 2864193 complement(1930820..1931947) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1947; (Fe-S)-binding protein 1931947 2864193 SAS1779 Staphylococcus aureus subsp. aureus MSSA476 (Fe-S)-binding protein YP_043896.1 1930820 R 282459 CDS YP_043897.1 49486676 2864082 complement(1932098..1932826) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1948; glutamine transport ATP-binding protein 1932826 2864082 SAS1780 Staphylococcus aureus subsp. aureus MSSA476 glutamine transport ATP-binding protein YP_043897.1 1932098 R 282459 CDS YP_043898.1 49486677 2864339 complement(1932813..1934270) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1949; extracellular glutamine-binding protein 1934270 2864339 SAS1781 Staphylococcus aureus subsp. aureus MSSA476 extracellular glutamine-binding protein YP_043898.1 1932813 R 282459 CDS YP_043899.1 49486678 2864340 complement(1934528..1935589) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1950; hypothetical protein 1935589 2864340 SAS1782 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043899.1 1934528 R 282459 CDS YP_043900.1 49486679 2862307 complement(1944450..1944896) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1951; peroxide operon regulator 1944896 2862307 SAS1783 Staphylococcus aureus subsp. aureus MSSA476 peroxide operon regulator YP_043900.1 1944450 R 282459 CDS YP_043901.1 49486680 2862308 complement(1944993..1945943) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1952; hypothetical protein 1945943 2862308 SAS1784 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043901.1 1944993 R 282459 CDS YP_043902.1 49486681 2862560 complement(1945949..1946401) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1953; AhpC/TSA family protein 1946401 2862560 SAS1785 Staphylococcus aureus subsp. aureus MSSA476 AhpC/TSA family protein YP_043902.1 1945949 R 282459 CDS YP_043903.1 49486682 2862561 1946485..1947774 1 NC_002953.3 converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate; glutamate-1-semialdehyde aminotransferase 1947774 2862561 SAS1786 Staphylococcus aureus subsp. aureus MSSA476 glutamate-1-semialdehyde aminotransferase YP_043903.1 1946485 D 282459 CDS YP_043904.1 49486683 2862565 1948067..1949161 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1955; hypothetical protein 1949161 2862565 SAS1787 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043904.1 1948067 D 282459 CDS YP_043905.1 49486684 2862566 complement(1949353..1951089) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1956; ABC transporter ATP-binding protein 1951089 2862566 SAS1788 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_043905.1 1949353 R 282459 CDS YP_043906.1 49486685 2864049 complement(1951380..1951922) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1957; hypothetical protein 1951922 2864049 SAS1789 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043906.1 1951380 R 282459 CDS YP_043907.1 49486686 2862581 complement(1952224..1953261) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1958; HhH-GPD superfamily base excision DNA repair protein 1953261 2862581 SAS1790 Staphylococcus aureus subsp. aureus MSSA476 HhH-GPD superfamily base excision DNA repair protein YP_043907.1 1952224 R 282459 CDS YP_043908.1 49486687 2862582 1953413..1954390 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1959; hypothetical protein 1954390 2862582 SAS1791 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043908.1 1953413 D 282459 CDS YP_043909.1 49486688 2862583 complement(1954651..1955487) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1960; hypothetical protein 1955487 2862583 SAS1792 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043909.1 1954651 R 282459 CDS YP_043910.1 49486689 2862584 complement(1955496..1957013) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1961; hypothetical protein 1957013 2862584 SAS1793 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043910.1 1955496 R 282459 CDS YP_043911.1 49486690 2862011 complement(1957028..1957342) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1962; hypothetical protein 1957342 2862011 SAS1794 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043911.1 1957028 R 282459 CDS YP_043912.1 49486691 2862012 complement(1957320..1958138) 1 NC_002953.3 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1958138 recX 2862012 recX Staphylococcus aureus subsp. aureus MSSA476 recombination regulator RecX YP_043912.1 1957320 R 282459 CDS YP_043913.1 49486692 2862558 complement(1958399..1959208) 1 NC_002953.3 monofunctional; catalyzes the elongation of glycan strands in cell wall biosynthesis; glycosyltransferase 1959208 2862558 SAS1796 Staphylococcus aureus subsp. aureus MSSA476 glycosyltransferase YP_043913.1 1958399 R 282459 CDS YP_043914.1 49486693 2862559 complement(1959547..1960062) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1965; ThiJ/PfpI family protein 1960062 2862559 SAS1797 Staphylococcus aureus subsp. aureus MSSA476 ThiJ/PfpI family protein YP_043914.1 1959547 R 282459 CDS YP_043915.1 49486694 2863700 complement(1960193..1960354) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1966; hypothetical protein 1960354 2863700 SAS1798 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043915.1 1960193 R 282459 CDS YP_043916.1 49486695 2862536 1960578..1961729 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1967; hypothetical protein 1961729 2862536 SAS1799 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043916.1 1960578 D 282459 CDS YP_043917.1 49486696 2862537 complement(1961989..1962519) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1968; hypothetical protein 1962519 2862537 SAS1800 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043917.1 1961989 R 282459 CDS YP_043918.1 49486697 2862364 complement(1962608..1963855) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1969; aminopeptidase 1963855 2862364 SAS1801 Staphylococcus aureus subsp. aureus MSSA476 aminopeptidase YP_043918.1 1962608 R 282459 CDS YP_043919.1 49486698 2862365 complement(1963867..1964082) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1970; hypothetical protein 1964082 2862365 SAS1802 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043919.1 1963867 R 282459 CDS YP_043920.1 49486699 2862907 1964214..1964678 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1971; low molecular weight phosphotyrosine protein phosphatase 1964678 2862907 SAS1803 Staphylococcus aureus subsp. aureus MSSA476 low molecular weight phosphotyrosine protein phosphatase YP_043920.1 1964214 D 282459 CDS YP_043921.1 49486700 2862908 1964685..1964960 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1972; hypothetical protein 1964960 2862908 SAS1804 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043921.1 1964685 D 282459 CDS YP_043922.1 49486701 2863784 1965238..1966449 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1973; hypothetical protein 1966449 2863784 SAS1805 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043922.1 1965238 D 282459 CDS YP_043923.1 49486702 2863785 complement(1966561..1967190) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1974; response regulator 1967190 2863785 SAS1806 Staphylococcus aureus subsp. aureus MSSA476 response regulator YP_043923.1 1966561 R 282459 CDS YP_043924.1 49486703 2862370 complement(1967180..1968223) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1975; histidine kinase sensor 1968223 2862370 SAS1807 Staphylococcus aureus subsp. aureus MSSA476 histidine kinase sensor YP_043924.1 1967180 R 282459 CDS YP_043925.1 49486704 2863196 complement(1968220..1968921) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1976; hypothetical protein 1968921 2863196 SAS1808 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043925.1 1968220 R 282459 CDS YP_043926.1 49486705 2863197 complement(1968936..1969322) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1977; hypothetical protein 1969322 2863197 SAS1809 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043926.1 1968936 R 282459 CDS YP_043927.1 49486706 2863190 complement(1969539..1970297) 1 NC_002953.3 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1970297 2863190 SAS1810 Staphylococcus aureus subsp. aureus MSSA476 methionine aminopeptidase YP_043927.1 1969539 R 282459 CDS YP_043928.1 49486707 2863191 1970828..1971814 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1980; hypothetical protein 1971814 2863191 SAS1811 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043928.1 1970828 D 282459 CDS YP_043929.1 49486708 2863494 complement(1972112..1972228) 1 NC_002953.3 Doubtful CDS. No database matches; hypothetical protein 1972228 2863494 SAS1811a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043929.1 1972112 R 282459 CDS YP_043930.1 49486709 2863495 complement(1972304..1972717) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1981; hypothetical protein 1972717 2863495 SAS1812 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043930.1 1972304 R 282459 CDS YP_043931.1 49486710 2863393 complement(1972943..1973674) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1982; hypothetical protein 1973674 2863393 SAS1813 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043931.1 1972943 R 282459 CDS YP_043932.1 49486711 2863394 complement(1973676..1974989) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1983; Mur ligase family protein 1974989 2863394 SAS1814 Staphylococcus aureus subsp. aureus MSSA476 Mur ligase family protein YP_043932.1 1973676 R 282459 CDS YP_043933.1 49486712 2863022 1975281..1975781 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1984; ferritin 1975781 2863022 SAS1815 Staphylococcus aureus subsp. aureus MSSA476 ferritin YP_043933.1 1975281 D 282459 CDS YP_043934.1 49486713 2863389 1976171..1976725 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1985; exonuclease 1976725 2863389 SAS1816 Staphylococcus aureus subsp. aureus MSSA476 exonuclease YP_043934.1 1976171 D 282459 CDS YP_043935.1 49486714 2863390 complement(1976792..1977862) 1 NC_002953.3 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 1977862 2863390 SAS1817 Staphylococcus aureus subsp. aureus MSSA476 DNA polymerase IV YP_043935.1 1976792 R 282459 CDS YP_043936.1 49486715 2863803 complement(1978109..1978639) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1987; hypothetical protein 1978639 2863803 SAS1818 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043936.1 1978109 R 282459 CDS YP_043937.1 49486716 2863804 complement(1978809..1980170) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1988; RNA methyltransferase 1980170 2863804 SAS1819 Staphylococcus aureus subsp. aureus MSSA476 RNA methyltransferase YP_043937.1 1978809 R 282459 CDS YP_043938.1 49486717 2862338 complement(1980251..1981198) 1 NC_002953.3 similar to YegS from E. coli; lipid kinase 1981198 2862338 SAS1820 Staphylococcus aureus subsp. aureus MSSA476 lipid kinase YP_043938.1 1980251 R 282459 CDS YP_043939.1 49486718 2862339 complement(1981852..1983279) 1 NC_002953.3 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1983279 gatB 2862339 gatB Staphylococcus aureus subsp. aureus MSSA476 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_043939.1 1981852 R 282459 CDS YP_043940.1 49486719 2861890 complement(1983292..1984749) 1 NC_002953.3 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1984749 gatA 2861890 gatA Staphylococcus aureus subsp. aureus MSSA476 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_043940.1 1983292 R 282459 CDS YP_043941.1 49486720 2861891 complement(1984751..1985053) 1 NC_002953.3 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 1985053 gatC 2861891 gatC Staphylococcus aureus subsp. aureus MSSA476 aspartyl/glutamyl-tRNA amidotransferase subunit C YP_043941.1 1984751 R 282459 CDS YP_043942.1 49486721 2862224 1985420..1986958 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1994; high affinity proline permease 1986958 2862224 SAS1825 Staphylococcus aureus subsp. aureus MSSA476 high affinity proline permease YP_043942.1 1985420 D 282459 CDS YP_043943.1 49486722 2863172 complement(1987047..1988246) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1995; lipoprotein 1988246 2863172 SAS1826 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_043943.1 1987047 R 282459 CDS YP_043944.1 49486723 2863173 complement(1988259..1990262) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1996; DNA ligase 1990262 2863173 SAS1827 Staphylococcus aureus subsp. aureus MSSA476 DNA ligase YP_043944.1 1988259 R 282459 CDS YP_043945.1 49486724 2862394 complement(1990266..1992458) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1997; ATP-dependent DNA helicase 1992458 2862394 SAS1828 Staphylococcus aureus subsp. aureus MSSA476 ATP-dependent DNA helicase YP_043945.1 1990266 R 282459 CDS YP_043946.1 49486725 2862395 complement(1992455..1993147) 1 NC_002953.3 PcrB-like protein; GGGP synthase; member of prenyltransferases that transfer isoprenoid groups to nonisoprenoid acceptors; functions in form GGGP from glycerol-1-phosphate (G-1-P) and geranylgeranyl pyrophosphate (GGPP); important in lipid metabolism and especially important as the ether linkages in archaea are different than those in bacteria; GGGP synthase lies at the branch point for membrane lipid biosynthesis; cytosolic; T acidophilum protein acts as a homodimer while M thermoautotrophicum protein has been reported to function as a pentamer; geranylgeranylglyceryl phosphate synthase 1993147 2862395 SAS1829 Staphylococcus aureus subsp. aureus MSSA476 geranylgeranylglyceryl phosphate synthase YP_043946.1 1992455 R 282459 CDS YP_043947.1 49486726 2864218 complement(1993319..1993621) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1999; hypothetical protein 1993621 2864218 SAS1830 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043947.1 1993319 R 282459 CDS YP_043948.1 49486727 2864219 complement(1993730..1995025) 1 NC_002953.3 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1995025 2864219 SAS1831 Staphylococcus aureus subsp. aureus MSSA476 adenylosuccinate lyase YP_043948.1 1993730 R 282459 CDS YP_043949.1 49486728 2862827 1995886..1997052 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2001; staphopain protease 1997052 2862827 SAS1832 Staphylococcus aureus subsp. aureus MSSA476 staphopain protease YP_043949.1 1995886 D 282459 CDS YP_043950.1 49486729 2862828 1997083..1997409 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2002; hypothetical protein 1997409 2862828 SAS1833 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043950.1 1997083 D 282459 CDS YP_043951.1 49486730 2863906 complement(1997701..1997874) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2003; hypothetical protein 1997874 2863906 SAS1834 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043951.1 1997701 R 282459 CDS YP_043952.1 49486731 2862132 complement(1997855..1998457) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2004; hypothetical protein 1998457 2862132 SAS1835 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043952.1 1997855 R 282459 CDS YP_043953.1 49486732 2862133 complement(1998728..1999549) 1 NC_002953.3 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1999549 nadE 2862133 nadE Staphylococcus aureus subsp. aureus MSSA476 NAD synthetase YP_043953.1 1998728 R 282459 CDS YP_043954.1 49486733 2862127 complement(1999542..2001011) 1 NC_002953.3 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 2001011 2862127 SAS1837 Staphylococcus aureus subsp. aureus MSSA476 nicotinate phosphoribosyltransferase YP_043954.1 1999542 R 282459 CDS YP_043955.1 49486734 2862128 2001195..2002271 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2007; oxygenase 2002271 2862128 SAS1838 Staphylococcus aureus subsp. aureus MSSA476 oxygenase YP_043955.1 2001195 D 282459 CDS YP_043956.1 49486735 2862145 2002291..2003085 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2008; prephenate dehydratase 2003085 2862145 SAS1839 Staphylococcus aureus subsp. aureus MSSA476 prephenate dehydratase YP_043956.1 2002291 D 282459 CDS YP_043957.1 49486736 2862146 complement(2003275..2004837) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2009; sodium:sulfate symporter 2004837 2862146 SAS1840 Staphylococcus aureus subsp. aureus MSSA476 sodium:sulfate symporter YP_043957.1 2003275 R 282459 CDS YP_043958.1 49486737 2862153 complement(2005042..2006139) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2010; hypothetical protein 2006139 2862153 SAS1841 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043958.1 2005042 R 282459 CDS YP_043959.1 49486738 2862154 2006511..2007071 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2011; isochorismatase family protein 2007071 2862154 SAS1842 Staphylococcus aureus subsp. aureus MSSA476 isochorismatase family protein YP_043959.1 2006511 D 282459 CDS YP_043960.1 49486739 2862858 2007118..2008053 1 NC_002953.3 catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase 2008053 2862858 SAS1843 Staphylococcus aureus subsp. aureus MSSA476 manganese-dependent inorganic pyrophosphatase YP_043960.1 2007118 D 282459 CDS YP_043961.1 49486740 2862073 2008473..2009852 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2013; aldehyde dehydrogenase 2009852 2862073 SAS1844 Staphylococcus aureus subsp. aureus MSSA476 aldehyde dehydrogenase YP_043961.1 2008473 D 282459 CDS YP_043962.1 49486741 2862074 complement(2009972..2011000) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2014; hypothetical protein 2011000 2862074 SAS1845 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043962.1 2009972 R 282459 CDS YP_043963.1 49486742 2863586 2011270..2011671 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2015; hypothetical protein 2011671 2863586 SAS1846 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043963.1 2011270 D 282459 CDS YP_043964.1 49486743 2861754 complement(2012244..2012417) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2016; hypothetical protein 2012417 2861754 SAS1848 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043964.1 2012244 R 282459 CDS YP_043965.1 49486744 2861755 2012868..2013908 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2017; hypothetical protein 2013908 2861755 SAS1849 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043965.1 2012868 D 282459 CDS YP_043966.1 49486745 2863812 complement(2013965..2014807) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2018; hypothetical protein 2014807 2863812 SAS1850 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043966.1 2013965 R 282459 CDS YP_043967.1 49486746 2863813 complement(2014804..2015361) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2019; hypothetical protein 2015361 2863813 SAS1851 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043967.1 2014804 R 282459 CDS YP_043968.1 49486747 2863246 complement(2015421..2015945) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2020; hypothetical protein 2015945 2863246 SAS1852 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043968.1 2015421 R 282459 CDS YP_043969.1 49486748 2861802 2016066..2016629 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2021; hypothetical protein 2016629 2861802 SAS1853 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043969.1 2016066 D 282459 CDS YP_043970.1 49486749 2861803 complement(2016695..2017435) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2022; hypothetical protein 2017435 2861803 SAS1854 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043970.1 2016695 R 282459 CDS YP_043971.1 49486750 2862113 complement(2017435..2018307) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2023; ABC transporter ATP-binding protein 2018307 2862113 SAS1855 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_043971.1 2017435 R 282459 CDS YP_043972.1 49486751 2862114 complement(2018304..2018984) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2024; hypothetical protein 2018984 2862114 SAS1856 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043972.1 2018304 R 282459 CDS YP_043973.1 49486752 2862891 complement(2018985..2019881) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2025; ABC transporter ATP-binding protein 2019881 2862891 SAS1857 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_043973.1 2018985 R 282459 CDS YP_043974.1 49486753 2862892 complement(2019878..2020333) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2026; GntR family transcriptional regulator 2020333 2862892 SAS1858 Staphylococcus aureus subsp. aureus MSSA476 GntR family transcriptional regulator YP_043974.1 2019878 R 282459 CDS YP_043975.1 49486754 2861824 complement(2020517..2020693) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2027; hypothetical protein 2020693 2861824 SAS1859 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043975.1 2020517 R 282459 CDS YP_043976.1 49486755 3248051 complement(2020936..2021034) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2027a; Doubtful CDS. No database matches; hypothetical protein 2021034 3248051 SAS1859.1 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043976.1 2020936 R 282459 CDS YP_043977.1 49486756 2861825 2021234..2022520 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2028; hypothetical protein 2022520 2861825 SAS1860 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043977.1 2021234 D 282459 CDS YP_043978.1 49486757 2864040 2025851..2026030 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2032; hypothetical protein 2026030 2864040 SAS1863a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043978.1 2025851 D 282459 CDS YP_043979.1 49486758 2864041 2026054..2026362 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2033; hypothetical protein 2026362 2864041 SAS1864 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043979.1 2026054 D 282459 CDS YP_043980.1 49486759 2864417 2026410..2026601 1 NC_002953.3 hypothetical protein 2026601 2864417 SAS1865 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043980.1 2026410 D 282459 CDS YP_043981.1 49486760 2864418 complement(2026654..2027004) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2035; hypothetical protein 2027004 2864418 SAS1866 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043981.1 2026654 R 282459 CDS YP_043982.1 49486761 2863311 complement(2028502..2028993) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2039; staphylokinase precursor 2028993 2863311 SAS1868 Staphylococcus aureus subsp. aureus MSSA476 staphylokinase precursor YP_043982.1 2028502 R 282459 CDS YP_043983.1 49486762 2864411 complement(2029184..2029939) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2040; Similar to the N-terminal region of Staphylococcus aureus autolysin LytA SWALL:ALYS_STAAU (SWALL:P24556) (481 aa) fasta scores: E(): 2.7e-07, 29.23% id in 260 aa, and to the full length Staphylococcus aureus phage phi 13 amidase SWALL:Q8SDJ9 (EMBL:AF424783) (251 aa) fasta scores: E(): 6.1e-108, 99.6% id in 251 aa. Possible gene remnant; autolysin 2029939 2864411 SAS1869 Staphylococcus aureus subsp. aureus MSSA476 autolysin YP_043983.1 2029184 R 282459 CDS YP_043984.1 49486763 2864412 complement(2029951..2030205) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2041; holin 2030205 2864412 SAS1870 Staphylococcus aureus subsp. aureus MSSA476 holin YP_043984.1 2029951 R 282459 CDS YP_043985.1 49486764 2862759 complement(2030417..2030602) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2042; hypothetical protein 2030602 2862759 SAS1871 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043985.1 2030417 R 282459 CDS YP_043986.1 49486765 2863260 complement(2030702..2031475) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2043; enterotoxin type A precursor 2031475 2863260 SAS1872 Staphylococcus aureus subsp. aureus MSSA476 enterotoxin type A precursor YP_043986.1 2030702 R 282459 CDS YP_043987.1 49486766 2863261 complement(2031848..2032222) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2045; hypothetical protein 2032222 2863261 SAS1873 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043987.1 2031848 R 282459 CDS YP_043988.1 49486767 2863363 complement(2032278..2032565) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2046; hypothetical protein 2032565 2863363 SAS1874 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043988.1 2032278 R 282459 CDS YP_043989.1 49486768 2863364 complement(2032611..2032763) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2047; hypothetical protein 2032763 2863364 SAS1875 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043989.1 2032611 R 282459 CDS YP_043990.1 49486769 2863058 complement(2032756..2036538) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2048; hypothetical protein 2036538 2863058 SAS1876 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043990.1 2032756 R 282459 CDS YP_043991.1 49486770 2863059 complement(2036554..2038044) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2049; hypothetical protein 2038044 2863059 SAS1877 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043991.1 2036554 R 282459 CDS YP_043992.1 49486771 2862767 complement(2038044..2042693) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2050; hypothetical protein 2042693 2862767 SAS1878 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043992.1 2038044 R 282459 CDS YP_043993.1 49486772 2862768 complement(2042749..2042871) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2051; hypothetical protein 2042871 2862768 SAS1879 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043993.1 2042749 R 282459 CDS YP_043994.1 49486773 2863638 complement(2042931..2043377) 1 NC_002953.3 Identical to Staphylococcus aureus phage phi 13, and Staphylococcus aureus prophage phiPV83 phi PVL orf 14-like protein SWALL:Q9MBP3 (EMBL:AF424783) (148 aa) fasta scores: E(): 1.5e-49, 100% id in 148 aa; hypothetical protein 2043377 2863638 SAS1880 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043994.1 2042931 R 282459 CDS YP_043995.1 49486774 2863255 complement(2043442..2044395) 1 NC_002953.3 Identical to Staphylococcus aureus phage phi 13 phi PVL orf 13-like protein SWALL:Q8SDK5 (EMBL:AF424783) (317 aa) fasta scores: E(): 7.8e-115, 100% id in 317 aa; hypothetical protein 2044395 2863255 SAS1881 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043995.1 2043442 R 282459 CDS YP_043996.1 49486775 2863256 complement(2044396..2044776) 1 NC_002953.3 Highly similar to Staphylococcus aureus phage phi 13 phi PVL orf 12-like protein SWALL:Q8SDK6 (EMBL:AF424783) (126 aa) fasta scores: E(): 2.7e-49, 99.2% id in 126 aa; hypothetical protein 2044776 2863256 SAS1882 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043996.1 2044396 R 282459 CDS YP_043997.1 49486776 2863626 complement(2044773..2045150) 1 NC_002953.3 Identical to Staphylococcus aureus phage phi 13, and Staphylococcus aureus prophage phiPV83 phi PVL orf 11-like protein SWALL:Q9MBP6 (EMBL:AF424783) (125 aa) fasta scores: E(): 2.5e-46, 100% id in 125 aa; hypothetical protein 2045150 2863626 SAS1883 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043997.1 2044773 R 282459 CDS YP_043998.1 49486777 2863627 complement(2045150..2045482) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2058; hypothetical protein 2045482 2863627 SAS1884 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043998.1 2045150 R 282459 CDS YP_043999.1 49486778 2864096 complement(2045472..2045804) 1 NC_002953.3 Identical to Staphylococcus aureus prophage phiPV83 orf 44a SWALL:Q9MBP8 (EMBL:AB044554) (113 aa) fasta scores: E(): 8.9e-44, 100% id in 109 aa; hypothetical protein 2045804 2864096 SAS1885 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_043999.1 2045472 R 282459 CDS YP_044000.1 49486779 2864097 complement(2045813..2045971) 1 NC_002953.3 Identical to Staphylococcus aureus bacteriophage PVL, Staphylococcus aureus prophage phiPV83, and Staphylococcus aureus phage phi 13 orf 8 SWALL:O80047 (EMBL:AB009866) (52 aa) fasta scores: E(): 3e-17, 100% id in 52 aa; hypothetical protein 2045971 2864097 SAS1886 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044000.1 2045813 R 282459 CDS YP_044001.1 49486780 2864068 complement(2046007..2047254) 1 NC_002953.3 Almost identical to Staphylococcus aureus phage phi 13 head protein SWALL:Q8SDK8 (EMBL:AF424783) (415 aa) fasta scores: E(): 1.8e-134, 99.75% id in 415 aa; capsid protein 2047254 2864068 SAS1887 Staphylococcus aureus subsp. aureus MSSA476 capsid protein YP_044001.1 2046007 R 282459 CDS YP_044002.1 49486781 2864069 complement(2047342..2047938) 1 NC_002953.3 Identical to Staphylococcus aureus phage phi 13, and Staphylococcus aureus prophage phiPV83 prohead protease SWALL:Q9MBP9 (EMBL:AF424783) (194 aa) fasta scores: E(): 1.7e-73, 100% id in 194 aa; prohead protease 2047938 2864069 SAS1888 Staphylococcus aureus subsp. aureus MSSA476 prohead protease YP_044002.1 2047342 R 282459 CDS YP_044003.1 49486782 2864111 complement(2047919..2049169) 1 NC_002953.3 Identical to Staphylococcus aureus bacteriophage PVL portal protein SWALL:O80043 (EMBL:AB009866) (416 aa) fasta scores: E(): 2.8e-159, 100% id in 416 aa; portal protein 2049169 2864111 SAS1889 Staphylococcus aureus subsp. aureus MSSA476 portal protein YP_044003.1 2047919 R 282459 CDS YP_044004.1 49486783 2862555 complement(2049175..2049375) 1 NC_002953.3 Almost identical to Staphylococcus aureus prophage phiPV83 phi PVL orf 3 homologue SWALL:Q9MBQ1 (EMBL:AB044554) (66 aa) fasta scores: E(): 3.2e-23, 98.48% id in 66 aa; hypothetical protein 2049375 2862555 SAS1890 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044004.1 2049175 R 282459 CDS YP_044005.1 49486784 2862556 complement(2049389..2051083) 1 NC_002953.3 Identical to Staphylococcus aureus phage phi 13, and Staphylococcus aureus prophage phiPV83 terminase-large subunit SWALL:Q9MBQ2 (EMBL:AF424783) (564 aa) fasta scores: E(): 0, 100% id in 564 aa; terminase-large subunit 2051083 2862556 SAS1891 Staphylococcus aureus subsp. aureus MSSA476 terminase-large subunit YP_044005.1 2049389 R 282459 CDS YP_044006.1 49486785 2864300 complement(2051086..2051553) 1 NC_002953.3 Identical to Staphylococcus aureus bacteriophage PVL, Staphylococcus aureus prophage phiPV83, and Staphylococcus aureus phage phi 13 orf 4 like protein SWALL:O80040 (EMBL:AB009866) (155 aa) fasta scores: E(): 8.7e-56, 100% id in 155 aa; hypothetical protein 2051553 2864300 SAS1892 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044006.1 2051086 R 282459 CDS YP_044007.1 49486786 2864301 complement(2051682..2052035) 1 NC_002953.3 Identical to Staphylococcus aureus prophage phiPV83 phi PVL orf 63 homologue SWALL:Q9MBQ3 (EMBL:AB044554) (117 aa) fasta scores: E(): 3.8e-50, 100% id in 117 aa; hypothetical protein 2052035 2864301 SAS1893 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044007.1 2051682 R 282459 CDS YP_044008.1 49486787 2863102 complement(2052042..2052494) 1 NC_002953.3 Almost identical to Staphylococcus aureus prophage phiPV83 phi PVL orf 62 homologue SWALL:Q9MBQ4 (EMBL:AB044554) (150 aa) fasta scores: E(): 1.9e-52, 98.66% id in 150 aa; hypothetical protein 2052494 2863102 SAS1894 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044008.1 2052042 R 282459 CDS YP_044009.1 49486788 2863103 complement(2052609..2053079) 1 NC_002953.3 Highly similar to Staphylococcus aureus prophage phiPV83 phi PVL orf 61 homologue SWALL:Q9MBQ5 (EMBL:AB044554) (153 aa) fasta scores: E(): 2e-48, 94.77% id in 153 aa; hypothetical protein 2053079 2863103 SAS1895 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044009.1 2052609 R 282459 CDS YP_044010.1 49486789 2862016 complement(2053102..2053305) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2068; hypothetical protein 2053305 2862016 SAS1896 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044010.1 2053102 R 282459 CDS YP_044011.1 49486790 2862017 complement(2053302..2053952) 1 NC_002953.3 Identical to Staphylococcus aureus bacteriophage PVL orf 59 SWALL:O80097 (EMBL:AB009866) (216 aa) fasta scores: E(): 1.2e-74, 100% id in 216 aa; hypothetical protein 2053952 2862017 SAS1897 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044011.1 2053302 R 282459 CDS YP_044012.1 49486791 2862580 complement(2053959..2054111) 1 NC_002953.3 Identical to Staphylococcus aureus bacteriophage PVL orf 58 SWALL:O80096 (EMBL:AB009866) (50 aa) fasta scores: E(): 1e-18, 100% id in 50 aa; hypothetical protein 2054111 2862580 SAS1898 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044012.1 2053959 R 282459 CDS YP_044013.1 49486792 2862810 complement(2054111..2054260) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2069; hypothetical protein 2054260 2862810 SAS1899 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044013.1 2054111 R 282459 CDS YP_044014.1 49486793 2862227 complement(2054601..2055005) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2078; hypothetical protein 2055005 2862227 SAS1901 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044014.1 2054601 R 282459 CDS YP_044015.1 49486794 2862525 complement(2055014..2055232) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2080; hypothetical protein 2055232 2862525 SAS1902 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044015.1 2055014 R 282459 CDS YP_044016.1 49486795 2862526 complement(2055239..2056132) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2082; phage regulatory protein 2056132 2862526 SAS1903 Staphylococcus aureus subsp. aureus MSSA476 phage regulatory protein YP_044016.1 2055239 R 282459 CDS YP_044017.1 49486796 2864279 complement(2056162..2056632) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2083; single-strand DNA-binding protein 2056632 2864279 SAS1904 Staphylococcus aureus subsp. aureus MSSA476 single-strand DNA-binding protein YP_044017.1 2056162 R 282459 CDS YP_044018.1 49486797 2864280 complement(2056633..2057118) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2084; hypothetical protein 2057118 2864280 SAS1905 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044018.1 2056633 R 282459 CDS YP_044019.1 49486798 2863968 complement(2057331..2058251) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2085; hypothetical protein 2058251 2863968 SAS1906 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044019.1 2057331 R 282459 CDS YP_044020.1 49486799 2863695 complement(2058253..2060202) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2086; hypothetical protein 2060202 2863695 SAS1907 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044020.1 2058253 R 282459 CDS YP_044021.1 49486800 2863696 complement(2060205..2060483) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2087; hypothetical protein 2060483 2863696 SAS1908 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044021.1 2060205 R 282459 CDS YP_044022.1 49486801 2864357 complement(2060477..2060737) 1 NC_002953.3 Identical to Staphylococcus aureus phage phi 13 phi PVL orf 39-like protein SWALL:Q8SDM6 (EMBL:AF424783) (86 aa) fasta scores: E(): 1.5e-31, 100% id in 86 aa; hypothetical protein 2060737 2864357 SAS1909 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044022.1 2060477 R 282459 CDS YP_044023.1 49486802 2864358 complement(2060830..2060991) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2091; hypothetical protein 2060991 2864358 SAS1910 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044023.1 2060830 R 282459 CDS YP_044024.1 49486803 2863068 complement(2060988..2061308) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2092; hypothetical protein 2061308 2863068 SAS1911 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044024.1 2060988 R 282459 CDS YP_044025.1 49486804 2863069 2061364..2061999 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2093; hypothetical protein 2061999 2863069 SAS1912 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044025.1 2061364 D 282459 CDS YP_044026.1 49486805 2863977 complement(2062014..2062154) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2094; hypothetical protein 2062154 2863977 SAS1912a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044026.1 2062014 R 282459 CDS YP_044027.1 49486806 2863978 complement(2062185..2062382) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2095; hypothetical protein 2062382 2863978 SAS1913 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044027.1 2062185 R 282459 CDS YP_044028.1 49486807 2863756 2063200..2063739 1 NC_002953.3 Almost identical to Staphylococcus aureus phage phi 13 phi PVL orf 33-like protein SWALL:Q8SDN0 (EMBL:AF424783) (179 aa) fasta scores: E(): 1.1e-70, 99.44% id in 179 aa; hypothetical protein 2063739 2863756 SAS1916 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044028.1 2063200 D 282459 CDS YP_044029.1 49486808 2863757 complement(2063763..2064044) 1 NC_002953.3 Amost identical to Staphylococcus aureus phage phi 13 phi PVL orf 32-like protein SWALL:Q8SDN1 (EMBL:AF424783) (93 aa) fasta scores: E(): 5.8e-32, 98.92% id in 93 aa. Possible alternative translational start site; hypothetical protein 2064044 2863757 SAS1917 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044029.1 2063763 R 282459 CDS YP_044030.1 49486809 2863947 complement(2064041..2064265) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1555; regulatory protein 2064265 2863947 SAS1918 Staphylococcus aureus subsp. aureus MSSA476 regulatory protein YP_044030.1 2064041 R 282459 CDS YP_044031.1 49486810 2863948 2064424..2065194 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2100; repressor 2065194 2863948 SAS1919 Staphylococcus aureus subsp. aureus MSSA476 repressor YP_044031.1 2064424 D 282459 CDS YP_044032.1 49486811 2863890 2065390..2066118 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1920; enterotoxin 2066118 2863890 SAS1920 Staphylococcus aureus subsp. aureus MSSA476 enterotoxin YP_044032.1 2065390 D 282459 CDS YP_044033.1 49486812 2863891 2066142..2066870 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR1919; enterotoxin 2066870 2863891 SAS1921 Staphylococcus aureus subsp. aureus MSSA476 enterotoxin YP_044033.1 2066142 D 282459 CDS YP_044034.1 49486813 2862825 2066954..2067991 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2105; integrase 2067991 2862825 SAS1922 Staphylococcus aureus subsp. aureus MSSA476 integrase YP_044034.1 2066954 D 282459 CDS YP_044035.1 49486814 2862826 complement(2069110..2070126) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2107; leukocidin F subunit 2070126 2862826 SAS1924 Staphylococcus aureus subsp. aureus MSSA476 leukocidin F subunit YP_044035.1 2069110 R 282459 CDS YP_044036.1 49486815 2862835 complement(2070148..2071200) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2108; leukocidin S subunit 2071200 2862835 SAS1925 Staphylococcus aureus subsp. aureus MSSA476 leukocidin S subunit YP_044036.1 2070148 R 282459 CDS YP_044037.1 49486816 2861840 2071636..2072859 1 NC_002953.3 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2072859 2861840 SAS1926 Staphylococcus aureus subsp. aureus MSSA476 succinyl-diaminopimelate desuccinylase YP_044037.1 2071636 D 282459 CDS YP_044038.1 49486817 2861841 complement(2073231..2074076) 1 NC_002953.3 Similar to Streptomyces glaucescens tetracenomycin polyketide synthesis O-methyltransferase TcmP SWALL:TCMP_STRGA (SWALL:P39887) (270 aa) fasta scores: E(): 4.3e-11, 25.1% id in 243 aa, and to Methanosarcina acetivorans hypothetical protein ma3472 SWALL:Q8TKD5 (EMBL:AE011055) (274 aa) fasta scores: E(): 5.7e-24, 39.63% id in 270 aa; hypothetical protein 2074076 2861841 SAS1927 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044038.1 2073231 R 282459 CDS YP_044039.1 49486818 2861846 complement(2074138..2075049) 1 NC_002953.3 Similar to Bacillus subtilis ferrichrome-binding protein precursor fhud or bsu33320 SWALL:FHUD_BACSU (SWALL:P37580) (315 aa) fasta scores: E(): 5.7e-29, 38.66% id in 300 aa, and to Clostridium acetobutylicum ferrichrome-binding periplasmic proteinl, fhud cac0790 SWALL:Q97KX6 (EMBL:AE007594) (307 aa) fasta scores: E(): 4.4e-31, 37.71% id in 297 aa; ferrichrome-binding protein precursor 2075049 2861846 SAS1928 Staphylococcus aureus subsp. aureus MSSA476 ferrichrome-binding protein precursor YP_044039.1 2074138 R 282459 CDS YP_044040.1 49486819 2861847 2075210..2076517 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2111; sodium transport protein 2076517 2861847 SAS1929 Staphylococcus aureus subsp. aureus MSSA476 sodium transport protein YP_044040.1 2075210 D 282459 CDS YP_044041.1 49486820 2863954 complement(2077371..2077796) 1 NC_002953.3 Similar to Streptococcus agalactiae acetyltransferase, GNAT family sag0999 SWALL:Q8DZU8 (EMBL:AE014237) (143 aa) fasta scores: E(): 2.3e-10, 30.76% id in 130 aa, and to Rickettsia conorii similarity to histon and other protein acetyltransferase rc0741 SWALL:Q92HN0 (EMBL:AE008631) (149 aa) fasta scores: E(): 1.8e-07, 29.85% id in 134 aa; GNAT family acetyltransferase 2077796 2863954 SAS1930 Staphylococcus aureus subsp. aureus MSSA476 GNAT family acetyltransferase YP_044041.1 2077371 R 282459 CDS YP_044042.1 49486821 2861837 complement(2077920..2078438) 1 NC_002953.3 hypothetical protein 2078438 2861837 SAS1931 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044042.1 2077920 R 282459 CDS YP_044043.1 49486822 2862079 complement(2078674..2079264) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR0382; terminase small subunit 2079264 2862079 SAS1932 Staphylococcus aureus subsp. aureus MSSA476 terminase small subunit YP_044043.1 2078674 R 282459 CDS YP_044044.1 49486823 2862080 complement(2079261..2079476) 1 NC_002953.3 Poor database matches. Weakly similar to C-terminal region of Bacillus subtilis YjcO protein SWALL:O31637 (EMBL:Z99110) (153 aa) fasta scores: E(): 0.56, 25% id in 60 aa; hypothetical protein 2079476 2862080 SAS1933 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044044.1 2079261 R 282459 CDS YP_044045.1 49486824 2863816 complement(2080175..2081791) 1 NC_002953.3 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 2081791 groEL 2863816 groEL Staphylococcus aureus subsp. aureus MSSA476 molecular chaperone GroEL YP_044045.1 2080175 R 282459 CDS YP_044046.1 49486825 2863817 complement(2081867..2082151) 1 NC_002953.3 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 2082151 groES 2863817 groES Staphylococcus aureus subsp. aureus MSSA476 co-chaperonin GroES YP_044046.1 2081867 R 282459 CDS YP_044047.1 49486826 2863582 2082326..2083069 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2118; hypothetical protein 2083069 2863582 SAS1937 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044047.1 2082326 D 282459 CDS YP_044048.1 49486827 2863583 complement(2083094..2084236) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2119; membrane anchored protein 2084236 2863583 SAS1938 Staphylococcus aureus subsp. aureus MSSA476 membrane anchored protein YP_044048.1 2083094 R 282459 CDS YP_044049.1 49486828 2863166 2084433..2085059 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2120; hypothetical protein 2085059 2863166 SAS1939 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044049.1 2084433 D 282459 CDS YP_044050.1 49486829 2863167 2085420..2086205 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2121; carbon-nitrogen hydrolase 2086205 2863167 SAS1940 Staphylococcus aureus subsp. aureus MSSA476 carbon-nitrogen hydrolase YP_044050.1 2085420 D 282459 CDS YP_044051.1 49486830 2862130 complement(2086804..2086941) 1 NC_002953.3 Lyses erythrocytes and other mammalian cells; delta-hemolysin 2086941 2862130 SAS1940a Staphylococcus aureus subsp. aureus MSSA476 delta-hemolysin YP_044051.1 2086804 R 282459 CDS YP_044052.1 49486831 2862131 2087174..2087737 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2123; autoinducer processing protein 2087737 2862131 SAS1941 Staphylococcus aureus subsp. aureus MSSA476 autoinducer processing protein YP_044052.1 2087174 D 282459 CDS YP_044053.1 49486832 2863204 2087741..2087881 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2124; autoinducer peptide 2087881 2863204 SAS1942 Staphylococcus aureus subsp. aureus MSSA476 autoinducer peptide YP_044053.1 2087741 D 282459 CDS YP_044054.1 49486833 2861869 2087906..2089198 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2125; autoinducer sensor protein 2089198 2861869 SAS1943 Staphylococcus aureus subsp. aureus MSSA476 autoinducer sensor protein YP_044054.1 2087906 D 282459 CDS YP_044055.1 49486834 2861870 2089217..2089933 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2126; autoinducer sensor protein response regulator protein 2089933 2861870 SAS1944 Staphylococcus aureus subsp. aureus MSSA476 autoinducer sensor protein response regulator protein YP_044055.1 2089217 D 282459 CDS YP_044056.1 49486835 2863850 complement(2090302..2091261) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2127; fructokinase 2091261 2863850 SAS1945 Staphylococcus aureus subsp. aureus MSSA476 fructokinase YP_044056.1 2090302 R 282459 CDS YP_044057.1 49486836 2863851 complement(2091258..2092742) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2128; sucrose-6-phosphate hydrolase 2092742 2863851 SAS1946 Staphylococcus aureus subsp. aureus MSSA476 sucrose-6-phosphate hydrolase YP_044057.1 2091258 R 282459 CDS YP_044058.1 49486837 2862884 complement(2092891..2093841) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2129; sucrose operon repressor 2093841 2862884 SAS1947 Staphylococcus aureus subsp. aureus MSSA476 sucrose operon repressor YP_044058.1 2092891 R 282459 CDS YP_044059.1 49486838 2862885 complement(2094024..2095274) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2130; ammonium transporter family protein 2095274 2862885 SAS1948 Staphylococcus aureus subsp. aureus MSSA476 ammonium transporter family protein YP_044059.1 2094024 R 282459 CDS YP_044060.1 49486839 2863322 complement(2095482..2095706) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2131; hypothetical protein 2095706 2863322 SAS1949 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044060.1 2095482 R 282459 CDS YP_044061.1 49486840 2863323 complement(2095766..2096845) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2132; hypothetical protein 2096845 2863323 SAS1950 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044061.1 2095766 R 282459 CDS YP_044062.1 49486841 2864035 complement(2097149..2097784) 1 NC_002953.3 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 2097784 2864035 SAS1951 Staphylococcus aureus subsp. aureus MSSA476 redox-sensing transcriptional repressor Rex YP_044062.1 2097149 R 282459 CDS YP_044063.1 49486842 2862898 2098037..2099965 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2134; ABC transporter ATP-binding protein 2099965 2862898 SAS1952 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_044063.1 2098037 D 282459 CDS YP_044064.1 49486843 2862899 2100327..2101937 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2135; hypothetical protein 2101937 2862899 SAS1953 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044064.1 2100327 D 282459 CDS YP_044065.1 49486844 2862107 complement(2102039..2103064) 1 NC_002953.3 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 2103064 2862107 SAS1954 Staphylococcus aureus subsp. aureus MSSA476 DNA-binding/iron metalloprotein/AP endonuclease YP_044065.1 2102039 R 282459 CDS YP_044066.1 49486845 2862108 complement(2103057..2103521) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2137; acetyltransferase 2103521 2862108 SAS1955 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase YP_044066.1 2103057 R 282459 CDS YP_044067.1 49486846 2862936 complement(2103494..2104156) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2138; hypothetical protein 2104156 2862936 SAS1956 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044067.1 2103494 R 282459 CDS YP_044068.1 49486847 2862937 complement(2104137..2104631) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2139; hypothetical protein 2104631 2862937 SAS1957 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044068.1 2104137 R 282459 CDS YP_044069.1 49486848 2863003 2105109..2106797 1 NC_002953.3 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 2106797 2863003 SAS1958 Staphylococcus aureus subsp. aureus MSSA476 dihydroxy-acid dehydratase YP_044069.1 2105109 D 282459 CDS YP_044070.1 49486849 2863004 2106825..2108594 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2141; acetolactate synthase large subunit 2108594 2863004 SAS1959 Staphylococcus aureus subsp. aureus MSSA476 acetolactate synthase large subunit YP_044070.1 2106825 D 282459 CDS YP_044071.1 49486850 2861757 2108985..2109989 1 NC_002953.3 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 2109989 2861757 SAS1961 Staphylococcus aureus subsp. aureus MSSA476 ketol-acid reductoisomerase YP_044071.1 2108985 D 282459 CDS YP_044072.1 49486851 2861758 2110019..2111548 1 NC_002953.3 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 2111548 2861758 SAS1962 Staphylococcus aureus subsp. aureus MSSA476 2-isopropylmalate synthase YP_044072.1 2110019 D 282459 CDS YP_044073.1 49486852 2864415 2111551..2112597 1 NC_002953.3 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 2112597 2864415 SAS1963 Staphylococcus aureus subsp. aureus MSSA476 3-isopropylmalate dehydrogenase YP_044073.1 2111551 D 282459 CDS YP_044074.1 49486853 2864416 2112611..2113981 1 NC_002953.3 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 2113981 2864416 SAS1964 Staphylococcus aureus subsp. aureus MSSA476 isopropylmalate isomerase large subunit YP_044074.1 2112611 D 282459 CDS YP_044075.1 49486854 2861791 2113982..2114554 1 NC_002953.3 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 2114554 leuD 2861791 leuD Staphylococcus aureus subsp. aureus MSSA476 isopropylmalate isomerase small subunit YP_044075.1 2113982 D 282459 CDS YP_044076.1 49486855 2861792 2114569..2115837 1 NC_002953.3 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 2115837 2861792 SAS1966 Staphylococcus aureus subsp. aureus MSSA476 threonine dehydratase YP_044076.1 2114569 D 282459 CDS YP_044077.1 49486856 2864438 complement(2122456..2122911) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2150; hypothetical protein 2122911 2864438 SAS1967 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044077.1 2122456 R 282459 CDS YP_044078.1 49486857 2864439 complement(2122904..2125054) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2151; RNA binding protein 2125054 2864439 SAS1968 Staphylococcus aureus subsp. aureus MSSA476 RNA binding protein YP_044078.1 2122904 R 282459 CDS YP_044079.1 49486858 2864373 complement(2125487..2126257) 1 NC_002953.3 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase; RNA polymerase sigma factor SigB 2126257 2864373 SAS1969 Staphylococcus aureus subsp. aureus MSSA476 RNA polymerase sigma factor SigB YP_044079.1 2125487 R 282459 CDS YP_044080.1 49486859 2864000 complement(2126232..2126711) 1 NC_002953.3 binds to sigma-B preventing the formation of an RNA polymerase holoenzyme; serine-protein kinase RsbW 2126711 2864000 SAS1970 Staphylococcus aureus subsp. aureus MSSA476 serine-protein kinase RsbW YP_044080.1 2126232 R 282459 CDS YP_044081.1 49486860 2864001 complement(2126713..2127039) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2154; anti-sigma B factor antagonist 2127039 2864001 SAS1971 Staphylococcus aureus subsp. aureus MSSA476 anti-sigma B factor antagonist YP_044081.1 2126713 R 282459 CDS YP_044082.1 49486861 2861805 complement(2127158..2128159) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2155; sigma factor sigB regulation protein 2128159 2861805 SAS1972 Staphylococcus aureus subsp. aureus MSSA476 sigma factor sigB regulation protein YP_044082.1 2127158 R 282459 CDS YP_044083.1 49486862 2861806 complement(2128508..2128870) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2156; hypothetical protein 2128870 2861806 SAS1973 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044083.1 2128508 R 282459 CDS YP_044084.1 49486863 2864436 complement(2128867..2129037) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2157; hypothetical protein 2129037 2864436 SAS1974 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044084.1 2128867 R 282459 CDS YP_044085.1 49486864 2864437 complement(2129122..2130270) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2158; alanine racemase 2130270 2864437 SAS1975 Staphylococcus aureus subsp. aureus MSSA476 alanine racemase YP_044085.1 2129122 R 282459 CDS YP_044086.1 49486865 2863343 complement(2130336..2130695) 1 NC_002953.3 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 2130695 acpS 2863343 acpS Staphylococcus aureus subsp. aureus MSSA476 4'-phosphopantetheinyl transferase YP_044086.1 2130336 R 282459 CDS YP_044087.1 49486866 2863344 complement(2130699..2131190) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2160; hypothetical protein 2131190 2863344 SAS1977 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044087.1 2130699 R 282459 CDS YP_044088.1 49486867 2863362 complement(2131177..2132760) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2161; hypothetical protein 2132760 2863362 SAS1978 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044088.1 2131177 R 282459 CDS YP_044089.1 49486868 2864456 complement(2132753..2133232) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2162; hypothetical protein 2133232 2864456 SAS1979 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044089.1 2132753 R 282459 CDS YP_044090.1 49486869 2864457 complement(2133441..2134001) 1 NC_002953.3 one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 2134001 2864457 SAS1980 Staphylococcus aureus subsp. aureus MSSA476 potassium-transporting ATPase subunit C YP_044090.1 2133441 R 282459 CDS YP_044091.1 49486870 2862632 complement(2134021..2136048) 1 NC_002953.3 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 2136048 2862632 SAS1981 Staphylococcus aureus subsp. aureus MSSA476 potassium-transporting ATPase subunit B YP_044091.1 2134021 R 282459 CDS YP_044092.1 49486871 2862633 complement(2136067..2137743) 1 NC_002953.3 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 2137743 2862633 SAS1982 Staphylococcus aureus subsp. aureus MSSA476 potassium-transporting ATPase subunit A YP_044092.1 2136067 R 282459 CDS YP_044093.1 49486872 2863485 2138015..2140672 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2166; sensor kinase 2140672 2863485 SAS1983 Staphylococcus aureus subsp. aureus MSSA476 sensor kinase YP_044093.1 2138015 D 282459 CDS YP_044094.1 49486873 2863486 2140672..2141367 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2167; response regulator protein 2141367 2863486 SAS1984 Staphylococcus aureus subsp. aureus MSSA476 response regulator protein YP_044094.1 2140672 D 282459 CDS YP_044095.1 49486874 2863379 complement(2141736..2143256) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2168; helicase 2143256 2863379 SAS1985 Staphylococcus aureus subsp. aureus MSSA476 helicase YP_044095.1 2141736 R 282459 CDS YP_044096.1 49486875 2863380 complement(2143773..2145131) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2169; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-- D-alanyl-D-alanyl ligase 2145131 2863380 SAS1986 Staphylococcus aureus subsp. aureus MSSA476 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-- D-alanyl-D-alanyl ligase YP_044096.1 2143773 R 282459 CDS YP_044097.1 49486876 2862609 complement(2145146..2146216) 1 NC_002953.3 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 2146216 ddl 2862609 ddl Staphylococcus aureus subsp. aureus MSSA476 D-alanyl-alanine synthetase A YP_044097.1 2145146 R 282459 CDS YP_044098.1 49486877 2862682 2146513..2147715 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2171; hypothetical protein 2147715 2862682 SAS1988 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044098.1 2146513 D 282459 CDS YP_044099.1 49486878 2862683 complement(2147978..2148115) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2173; hypothetical protein 2148115 2862683 SAS1989 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044099.1 2147978 R 282459 CDS YP_044100.1 49486879 2863356 complement(2148243..2148452) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2174; hypothetical protein 2148452 2863356 SAS1990 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044100.1 2148243 R 282459 CDS YP_044101.1 49486880 2863357 complement(2148464..2148757) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2175; hypothetical protein 2148757 2863357 SAS1991 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044101.1 2148464 R 282459 CDS YP_044102.1 49486881 2862605 2148923..2150407 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2177; cardiolipin synthetase 2150407 2862605 SAS1992 Staphylococcus aureus subsp. aureus MSSA476 cardiolipin synthetase YP_044102.1 2148923 D 282459 CDS YP_044103.1 49486882 2862606 2150435..2151082 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2178; hypothetical protein 2151082 2862606 SAS1993 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044103.1 2150435 D 282459 CDS YP_044104.1 49486883 2863652 complement(2151696..2152568) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2179; hypothetical protein 2152568 2863652 SAS1994 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044104.1 2151696 R 282459 CDS YP_044105.1 49486884 2863653 complement(2152654..2153295) 1 NC_002953.3 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 2153295 thiE 2863653 thiE Staphylococcus aureus subsp. aureus MSSA476 thiamine-phosphate pyrophosphorylase YP_044105.1 2152654 R 282459 CDS YP_044106.1 49486885 2863648 complement(2153288..2154088) 1 NC_002953.3 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 2154088 2863648 SAS1996 Staphylococcus aureus subsp. aureus MSSA476 hydroxyethylthiazole kinase YP_044106.1 2153288 R 282459 CDS YP_044107.1 49486886 2862613 complement(2154072..2154902) 1 NC_002953.3 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 2154902 2862613 SAS1997 Staphylococcus aureus subsp. aureus MSSA476 phosphomethylpyrimidine kinase YP_044107.1 2154072 R 282459 CDS YP_044108.1 49486887 2862614 complement(2154895..2155584) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2183; transcriptional activator 2155584 2862614 SAS1998 Staphylococcus aureus subsp. aureus MSSA476 transcriptional activator YP_044108.1 2154895 R 282459 CDS YP_044109.1 49486888 2863673 2155847..2156092 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2183b; Doubtful CDS. No database matches; hypothetical protein 2156092 2863673 SAS1998b Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044109.1 2155847 D 282459 CDS YP_044110.1 49486889 2863674 complement(2156108..2156803) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2184; hypothetical protein 2156803 2863674 SAS1999 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044110.1 2156108 R 282459 CDS YP_044111.1 49486890 2863223 complement(2157192..2157587) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2185; ssDNA-binding protein 2157587 2863223 SAS2000 Staphylococcus aureus subsp. aureus MSSA476 ssDNA-binding protein YP_044111.1 2157192 R 282459 CDS YP_044112.1 49486891 2863224 2157781..2158221 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2186; hypothetical protein 2158221 2863224 SAS2001 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044112.1 2157781 D 282459 CDS YP_044113.1 49486892 2863639 complement(2158279..2158719) 1 NC_002953.3 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 2158719 fabZ 2863639 fabZ Staphylococcus aureus subsp. aureus MSSA476 (3R)-hydroxymyristoyl-ACP dehydratase YP_044113.1 2158279 R 282459 CDS YP_044114.1 49486893 2863640 complement(2158753..2160018) 1 NC_002953.3 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2160018 2863640 SAS2003 Staphylococcus aureus subsp. aureus MSSA476 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_044114.1 2158753 R 282459 CDS YP_044115.1 49486894 2863658 complement(2160129..2160362) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2189; hypothetical protein 2160362 2863658 SAS2004 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044115.1 2160129 R 282459 CDS YP_044116.1 49486895 2863039 complement(2160924..2161328) 1 NC_002953.3 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 2161328 atpC 2863039 atpC Staphylococcus aureus subsp. aureus MSSA476 ATP synthase F0F1 subunit epsilon YP_044116.1 2160924 R 282459 CDS YP_044117.1 49486896 2863040 complement(2161348..2162760) 1 NC_002953.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 2162760 2863040 SAS2006 Staphylococcus aureus subsp. aureus MSSA476 ATP synthase F0F1 subunit beta YP_044117.1 2161348 R 282459 CDS YP_044118.1 49486897 2863095 complement(2162782..2163648) 1 NC_002953.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 2163648 2863095 SAS2007 Staphylococcus aureus subsp. aureus MSSA476 ATP synthase F0F1 subunit gamma YP_044118.1 2162782 R 282459 CDS YP_044119.1 49486898 2863096 complement(2163679..2165187) 1 NC_002953.3 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 2165187 2863096 SAS2008 Staphylococcus aureus subsp. aureus MSSA476 ATP synthase F0F1 subunit alpha YP_044119.1 2163679 R 282459 CDS YP_044120.1 49486899 2864084 complement(2165209..2165748) 1 NC_002953.3 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 2165748 2864084 SAS2009 Staphylococcus aureus subsp. aureus MSSA476 ATP synthase F0F1 subunit delta YP_044120.1 2165209 R 282459 CDS YP_044121.1 49486900 2864085 complement(2165748..2166269) 1 NC_002953.3 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit B is part of the membrane proton channel; ATP synthase F0F1 subunit B 2166269 2864085 SAS2010 Staphylococcus aureus subsp. aureus MSSA476 ATP synthase F0F1 subunit B YP_044121.1 2165748 R 282459 CDS YP_044122.1 49486901 2864063 complement(2166466..2166678) 1 NC_002953.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 2166678 2864063 SAS2011 Staphylococcus aureus subsp. aureus MSSA476 F0F1 ATP synthase subunit C YP_044122.1 2166466 R 282459 CDS YP_044123.1 49486902 2864064 complement(2166721..2167449) 1 NC_002953.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 2167449 2864064 SAS2012 Staphylococcus aureus subsp. aureus MSSA476 ATP synthase F0F1 subunit A YP_044123.1 2166721 R 282459 CDS YP_044124.1 49486903 2864077 complement(2167470..2167823) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2198; ATP synthase I 2167823 2864077 SAS2013 Staphylococcus aureus subsp. aureus MSSA476 ATP synthase I YP_044124.1 2167470 R 282459 CDS YP_044125.1 49486904 2864052 complement(2167990..2169120) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2199; UDP-GlcNAc 2-epimerase 2169120 2864052 SAS2014 Staphylococcus aureus subsp. aureus MSSA476 UDP-GlcNAc 2-epimerase YP_044125.1 2167990 R 282459 CDS YP_044126.1 49486905 2864053 complement(2169141..2169770) 1 NC_002953.3 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 2169770 upp 2864053 upp Staphylococcus aureus subsp. aureus MSSA476 uracil phosphoribosyltransferase YP_044126.1 2169141 R 282459 CDS YP_044127.1 49486906 2864332 complement(2169798..2171036) 1 NC_002953.3 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 2171036 glyA 2864332 glyA Staphylococcus aureus subsp. aureus MSSA476 serine hydroxymethyltransferase YP_044127.1 2169798 R 282459 CDS YP_044128.1 49486907 2864333 complement(2171063..2171587) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2202; hypothetical protein 2171587 2864333 SAS2017 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044128.1 2171063 R 282459 CDS YP_044129.1 49486908 2864105 complement(2171694..2172113) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2203; low molecular weight protein-tyrosine-phosphatase 2172113 2864105 SAS2018 Staphylococcus aureus subsp. aureus MSSA476 low molecular weight protein-tyrosine-phosphatase YP_044129.1 2171694 R 282459 CDS YP_044130.1 49486909 2864106 complement(2172110..2173156) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2204; hypothetical protein 2173156 2864106 SAS2019 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044130.1 2172110 R 282459 CDS YP_044131.1 49486910 2862290 complement(2173240..2174076) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2205; hypothetical protein 2174076 2862290 SAS2020 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044131.1 2173240 R 282459 CDS YP_044132.1 49486911 2862291 complement(2174063..2175139) 1 NC_002953.3 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 2175139 prfA 2862291 prfA Staphylococcus aureus subsp. aureus MSSA476 peptide chain release factor 1 YP_044132.1 2174063 R 282459 CDS YP_044133.1 49486912 2862254 complement(2175140..2175739) 1 NC_002953.3 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 2175739 2862254 SAS2022 Staphylococcus aureus subsp. aureus MSSA476 thymidine kinase YP_044133.1 2175140 R 282459 CDS YP_044134.1 49486913 2862286 complement(2176086..2176340) 1 NC_002953.3 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 2176340 rpmE2 2862286 rpmE2 Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L31 YP_044134.1 2176086 R 282459 CDS YP_044135.1 49486914 2862287 complement(2176458..2177774) 1 NC_002953.3 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 2177774 rho 2862287 rho Staphylococcus aureus subsp. aureus MSSA476 transcription termination factor Rho YP_044135.1 2176458 R 282459 CDS YP_044136.1 49486915 2862288 complement(2178021..2179448) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2210; aldehyde dehydrogenase 2179448 2862288 SAS2025 Staphylococcus aureus subsp. aureus MSSA476 aldehyde dehydrogenase YP_044136.1 2178021 R 282459 CDS YP_044137.1 49486916 2862289 complement(2179686..2180024) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2211; hypothetical protein 2180024 2862289 SAS2026 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044137.1 2179686 R 282459 CDS YP_044138.1 49486917 2862267 complement(2180110..2181369) 1 NC_002953.3 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2181369 2862267 SAS2027 Staphylococcus aureus subsp. aureus MSSA476 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_044138.1 2180110 R 282459 CDS YP_044139.1 49486918 2862268 complement(2181835..2182695) 1 NC_002953.3 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; induced by anaerobic conditions in Bacillus subtilis; fructose-bisphosphate aldolase 2182695 2862268 SAS2028 Staphylococcus aureus subsp. aureus MSSA476 fructose-bisphosphate aldolase YP_044139.1 2181835 R 282459 CDS YP_044140.1 49486919 2864158 2182913..2183434 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2214; hypothetical protein 2183434 2864158 SAS2029 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044140.1 2182913 D 282459 CDS YP_044141.1 49486920 2864159 complement(2183543..2185153) 1 NC_002953.3 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 2185153 pyrG 2864159 pyrG Staphylococcus aureus subsp. aureus MSSA476 CTP synthetase YP_044141.1 2183543 R 282459 CDS YP_044142.1 49486921 2862292 complement(2185489..2186019) 1 NC_002953.3 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 2186019 2862292 SAS2031 Staphylococcus aureus subsp. aureus MSSA476 DNA-directed RNA polymerase subunit delta YP_044142.1 2185489 R 282459 CDS YP_044143.1 49486922 2864160 complement(2186131..2186991) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2217; acetyltransferase 2186991 2864160 SAS2032 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase YP_044143.1 2186131 R 282459 CDS YP_044144.1 49486923 2864161 2187415..2188218 1 NC_002953.3 catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type II pantothenate kinases are not regulated by feedback inhibition by coenzyme A; pantothenate kinase 2188218 2864161 SAS2033 Staphylococcus aureus subsp. aureus MSSA476 pantothenate kinase YP_044144.1 2187415 D 282459 CDS YP_044145.1 49486924 2864176 complement(2188348..2189019) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2219; hypothetical protein 2189019 2864176 SAS2034 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044145.1 2188348 R 282459 CDS YP_044146.1 49486925 2864177 complement(2189418..2190611) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2220; hypothetical protein 2190611 2864177 SAS2035 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044146.1 2189418 R 282459 CDS YP_044147.1 49486926 2864204 complement(2190611..2191795) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2221; peptidase 2191795 2864204 SAS2036 Staphylococcus aureus subsp. aureus MSSA476 peptidase YP_044147.1 2190611 R 282459 CDS YP_044148.1 49486927 2864205 2192106..2192576 1 NC_002953.3 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 2192576 2864205 SAS2037 Staphylococcus aureus subsp. aureus MSSA476 S-ribosylhomocysteinase YP_044148.1 2192106 D 282459 CDS YP_044149.1 49486928 2862505 complement(2192728..2193078) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2223; hypothetical protein 2193078 2862505 SAS2038 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044149.1 2192728 R 282459 CDS YP_044150.1 49486929 2861947 complement(2193092..2194393) 1 NC_002953.3 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase 2194393 2861947 SAS2039 Staphylococcus aureus subsp. aureus MSSA476 pyrimidine-nucleoside phosphorylase YP_044150.1 2193092 R 282459 CDS YP_044151.1 49486930 2861998 complement(2194674..2195336) 1 NC_002953.3 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 2195336 2861998 SAS2040 Staphylococcus aureus subsp. aureus MSSA476 deoxyribose-phosphate aldolase YP_044151.1 2194674 R 282459 CDS YP_044152.1 49486931 2862553 2195651..2196361 1 NC_002953.3 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 2196361 deoD 2862553 deoD Staphylococcus aureus subsp. aureus MSSA476 purine nucleoside phosphorylase YP_044152.1 2195651 D 282459 CDS YP_044153.1 49486932 2862554 complement(2196482..2196925) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2227; non-heme iron-containing ferritin 2196925 2862554 SAS2042 Staphylococcus aureus subsp. aureus MSSA476 non-heme iron-containing ferritin YP_044153.1 2196482 R 282459 CDS YP_044154.1 49486933 2861964 complement(2197125..2197538) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2228; hypothetical protein 2197538 2861964 SAS2043 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044154.1 2197125 R 282459 CDS YP_044155.1 49486934 2861965 complement(2197996..2199369) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2229; hypothetical protein 2199369 2861965 SAS2044 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044155.1 2197996 R 282459 CDS YP_044156.1 49486935 2862549 complement(2200041..2200271) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2230; hypothetical protein 2200271 2862549 SAS2045 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044156.1 2200041 R 282459 CDS YP_044157.1 49486936 2862550 complement(2200302..2201240) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2231; mannose-6-phosphate isomerase 2201240 2862550 SAS2046 Staphylococcus aureus subsp. aureus MSSA476 mannose-6-phosphate isomerase YP_044157.1 2200302 R 282459 CDS YP_044158.1 49486937 2863180 complement(2201676..2202341) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2232; hypothetical protein 2202341 2863180 SAS2047 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044158.1 2201676 R 282459 CDS YP_044159.1 49486938 2863181 2202493..2202813 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2233; zinc and cobalt transport repressor protein 2202813 2863181 SAS2048 Staphylococcus aureus subsp. aureus MSSA476 zinc and cobalt transport repressor protein YP_044159.1 2202493 D 282459 CDS YP_044160.1 49486939 2862552 2202815..2203795 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2234; zinc resistance protein 2203795 2862552 SAS2049 Staphylococcus aureus subsp. aureus MSSA476 zinc resistance protein YP_044160.1 2202815 D 282459 CDS YP_044161.1 49486940 2863818 2204061..2205152 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2235; hypothetical protein 2205152 2863818 SAS2050 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044161.1 2204061 D 282459 CDS YP_044163.1 49486942 2863451 2206964..2207056 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2239; Doubtful CDS. No database matches; hypothetical protein 2207056 2863451 SAS2052a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044163.1 2206964 D 282459 CDS YP_044164.1 49486943 2863503 complement(2207186..2208043) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2240; haloacid dehalogenase 2208043 2863503 SAS2053 Staphylococcus aureus subsp. aureus MSSA476 haloacid dehalogenase YP_044164.1 2207186 R 282459 CDS YP_044165.1 49486944 2863504 complement(2208111..2208893) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2241; ABC transporter ATP-binding protein 2208893 2863504 SAS2054 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_044165.1 2208111 R 282459 CDS YP_044166.1 49486945 2861767 complement(2209125..2210930) 1 NC_002953.3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 2210930 2861767 SAS2055 Staphylococcus aureus subsp. aureus MSSA476 glucosamine--fructose-6-phosphate aminotransferase YP_044166.1 2209125 R 282459 CDS YP_044167.1 49486946 2861768 2211398..2211553 1 NC_002953.3 Doubtful CDS. No significant database hits; hypothetical protein 2211553 2861768 SAS2056 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044167.1 2211398 D 282459 CDS YP_044168.1 49486947 2862707 2211611..2213149 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2244; PTS system mannitol-specific transporter subunit IIBC 2213149 2862707 SAS2057 Staphylococcus aureus subsp. aureus MSSA476 PTS system mannitol-specific transporter subunit IIBC YP_044168.1 2211611 D 282459 CDS YP_044169.1 49486948 2863105 2213184..2215316 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2245; transcriptional antiterminator 2215316 2863105 SAS2058 Staphylococcus aureus subsp. aureus MSSA476 transcriptional antiterminator YP_044169.1 2213184 D 282459 CDS YP_044170.1 49486949 2863106 2215328..2215762 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2246; PTS system mannitol-specific transporter subunit IIA 2215762 2863106 SAS2059 Staphylococcus aureus subsp. aureus MSSA476 PTS system mannitol-specific transporter subunit IIA YP_044170.1 2215328 D 282459 CDS YP_044171.1 49486950 2862820 2215762..2216868 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2247; mannitol-1-phosphate 5-dehydrogenase 2216868 2862820 SAS2060 Staphylococcus aureus subsp. aureus MSSA476 mannitol-1-phosphate 5-dehydrogenase YP_044171.1 2215762 D 282459 CDS YP_044172.1 49486951 2862821 complement(2224979..2226334) 1 NC_002953.3 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 2226334 glmM 2862821 glmM Staphylococcus aureus subsp. aureus MSSA476 phosphoglucosamine mutase YP_044172.1 2224979 R 282459 CDS YP_044173.1 49486952 2862740 complement(2226361..2227293) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2253; hypothetical protein 2227293 2862740 SAS2064 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044173.1 2226361 R 282459 CDS YP_044174.1 49486953 2862741 complement(2227295..2228104) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2254; hypothetical protein 2228104 2862741 SAS2065 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044174.1 2227295 R 282459 CDS YP_044175.1 49486954 2863909 complement(2228293..2229201) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2255; arginase 2229201 2863909 SAS2066 Staphylococcus aureus subsp. aureus MSSA476 arginase YP_044175.1 2228293 R 282459 CDS YP_044176.1 49486955 2863910 complement(2235396..2236460) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2256; hypothetical protein 2236460 2863910 SAS2067 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044176.1 2235396 R 282459 CDS YP_044177.1 49486956 2862389 complement(2236608..2238050) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2257; transport protein 2238050 2862389 SAS2068 Staphylococcus aureus subsp. aureus MSSA476 transport protein YP_044177.1 2236608 R 282459 CDS YP_044178.1 49486957 2863345 complement(2238373..2238840) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2259; hypothetical protein 2238840 2863345 SAS2069 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044178.1 2238373 R 282459 CDS YP_044179.1 49486958 2863346 complement(2238945..2240288) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2260; transport protein 2240288 2863346 SAS2070 Staphylococcus aureus subsp. aureus MSSA476 transport protein YP_044179.1 2238945 R 282459 CDS YP_044180.1 49486959 2864311 complement(2240465..2241148) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2261; hypothetical protein 2241148 2864311 SAS2071 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044180.1 2240465 R 282459 CDS YP_044181.1 49486960 2864312 complement(2241167..2242354) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2262; UTP-glucose-1-phosphate uridylyltransferase 2242354 2864312 SAS2072 Staphylococcus aureus subsp. aureus MSSA476 UTP-glucose-1-phosphate uridylyltransferase YP_044181.1 2241167 R 282459 CDS YP_044182.1 49486961 2864167 complement(2242398..2242913) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2263; hypothetical protein 2242913 2864167 SAS2073 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044182.1 2242398 R 282459 CDS YP_044183.1 49486962 2864168 2243090..2243350 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2264; hypothetical protein 2243350 2864168 SAS2074 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044183.1 2243090 D 282459 CDS YP_044184.1 49486963 2862803 complement(2243482..2244852) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2265; hypothetical protein 2244852 2862803 SAS2075 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044184.1 2243482 R 282459 CDS YP_044185.1 49486964 2862804 complement(2245088..2246056) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2266; FecCD transport family protein 2246056 2862804 SAS2076 Staphylococcus aureus subsp. aureus MSSA476 FecCD transport family protein YP_044185.1 2245088 R 282459 CDS YP_044186.1 49486965 2862257 complement(2246053..2247084) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2267; FecCD transport family protein 2247084 2862257 SAS2077 Staphylococcus aureus subsp. aureus MSSA476 FecCD transport family protein YP_044186.1 2246053 R 282459 CDS YP_044187.1 49486966 2862734 complement(2247096..2248079) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2268; transport system binding lipoprotein 2248079 2862734 SAS2078 Staphylococcus aureus subsp. aureus MSSA476 transport system binding lipoprotein YP_044187.1 2247096 R 282459 CDS YP_044188.1 49486967 2862735 complement(2248471..2249541) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2269; hypothetical protein 2249541 2862735 SAS2079 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044188.1 2248471 R 282459 CDS YP_044189.1 49486968 2861800 complement(2249548..2251305) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2270; hypothetical protein 2251305 2861800 SAS2080 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044189.1 2249548 R 282459 CDS YP_044190.1 49486969 2861801 complement(2251292..2252485) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2271; hypothetical protein 2252485 2861801 SAS2081 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044190.1 2251292 R 282459 CDS YP_044191.1 49486970 2862792 2252587..2254563 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2272; hypothetical protein 2254563 2862792 SAS2082 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044191.1 2252587 D 282459 CDS YP_044192.1 49486971 2862793 complement(2254723..2255232) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2273; alkaline shock protein 23 2255232 2862793 SAS2083 Staphylococcus aureus subsp. aureus MSSA476 alkaline shock protein 23 YP_044192.1 2254723 R 282459 CDS YP_044193.1 49486972 2862179 complement(2255295..2255534) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2274; hypothetical protein 2255534 2862179 SAS2084 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044193.1 2255295 R 282459 CDS YP_044194.1 49486973 2862180 complement(2255547..2256083) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2275; hypothetical protein 2256083 2862180 SAS2085 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044194.1 2255547 R 282459 CDS YP_044195.1 49486974 2863964 complement(2256258..2257820) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2276; glycine betaine transporter 2 2257820 2863964 SAS2086 Staphylococcus aureus subsp. aureus MSSA476 glycine betaine transporter 2 YP_044195.1 2256258 R 282459 CDS YP_044196.1 49486975 2864229 complement(2258128..2259135) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2277; zinc-binding dehydrogenase 2259135 2864229 SAS2087 Staphylococcus aureus subsp. aureus MSSA476 zinc-binding dehydrogenase YP_044196.1 2258128 R 282459 CDS YP_044197.1 49486976 2864230 complement(2259369..2260373) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2278; zinc-binding dehydrogenase 2260373 2864230 SAS2088 Staphylococcus aureus subsp. aureus MSSA476 zinc-binding dehydrogenase YP_044197.1 2259369 R 282459 CDS YP_044198.1 49486977 2862723 complement(2260653..2261522) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2279; hypothetical protein 2261522 2862723 SAS2089 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044198.1 2260653 R 282459 CDS YP_044199.1 49486978 2862724 complement(2261788..2263200) 1 NC_002953.3 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; 6-phospho-beta-galactosidase 2263200 2862724 SAS2090 Staphylococcus aureus subsp. aureus MSSA476 6-phospho-beta-galactosidase YP_044199.1 2261788 R 282459 CDS YP_044200.1 49486979 2863141 complement(2263218..2264930) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2281; PTS system lactose-specific transporter subunit IIBC 2264930 2863141 SAS2091 Staphylococcus aureus subsp. aureus MSSA476 PTS system lactose-specific transporter subunit IIBC YP_044200.1 2263218 R 282459 CDS YP_044201.1 49486980 2863142 complement(2264936..2265247) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2282; PTS system lactose-specific transporter subunit IIA 2265247 2863142 SAS2092 Staphylococcus aureus subsp. aureus MSSA476 PTS system lactose-specific transporter subunit IIA YP_044201.1 2264936 R 282459 CDS YP_044202.1 49486981 2862753 complement(2265269..2266249) 1 NC_002953.3 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 2266249 2862753 SAS2093 Staphylococcus aureus subsp. aureus MSSA476 tagatose 1,6-diphosphate aldolase YP_044202.1 2265269 R 282459 CDS YP_044203.1 49486982 2862754 complement(2266253..2267185) 1 NC_002953.3 catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP; tagatose-6-phosphate kinase 2267185 2862754 SAS2094 Staphylococcus aureus subsp. aureus MSSA476 tagatose-6-phosphate kinase YP_044203.1 2266253 R 282459 CDS YP_044204.1 49486983 2862714 complement(2267198..2267713) 1 NC_002953.3 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; galactose-6-phosphate isomerase subunit LacB 2267713 2862714 SAS2095 Staphylococcus aureus subsp. aureus MSSA476 galactose-6-phosphate isomerase subunit LacB YP_044204.1 2267198 R 282459 CDS YP_044205.1 49486984 2863838 complement(2267729..2268157) 1 NC_002953.3 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization; galactose-6-phosphate isomerase subunit LacA 2268157 2863838 SAS2096 Staphylococcus aureus subsp. aureus MSSA476 galactose-6-phosphate isomerase subunit LacA YP_044205.1 2267729 R 282459 CDS YP_044206.1 49486985 2863839 complement(2268525..2269280) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2287; lactose phosphotransferase system repressor 2269280 2863839 SAS2097 Staphylococcus aureus subsp. aureus MSSA476 lactose phosphotransferase system repressor YP_044206.1 2268525 R 282459 CDS YP_044207.1 49486986 2862504 2269531..2270262 1 NC_002953.3 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 2270262 2862504 SAS2098 Staphylococcus aureus subsp. aureus MSSA476 NAD-dependent deacetylase YP_044207.1 2269531 D 282459 CDS YP_044208.1 49486987 2861871 2270311..2270460 1 NC_002953.3 Doubtful CDS. No significant database hits; hypothetical protein 2270460 2861871 SAS2099 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044208.1 2270311 D 282459 CDS YP_044209.1 49486988 2862294 complement(2270553..2271161) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2289; hypothetical protein 2271161 2862294 SAS2100 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044209.1 2270553 R 282459 CDS YP_044210.1 49486989 2862295 complement(2271423..2271548) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2289a; Doubtful CDS. No database matches; hypothetical protein 2271548 2862295 SAS2100a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044210.1 2271423 R 282459 CDS YP_044211.1 49486990 2863146 complement(2271767..2272615) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2290; aldo/keto reductase 2272615 2863146 SAS2101 Staphylococcus aureus subsp. aureus MSSA476 aldo/keto reductase YP_044211.1 2271767 R 282459 CDS YP_044212.1 49486991 2863147 complement(2272685..2273101) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2291; MerR family transcriptional regulator 2273101 2863147 SAS2102 Staphylococcus aureus subsp. aureus MSSA476 MerR family transcriptional regulator YP_044212.1 2272685 R 282459 CDS YP_044213.1 49486992 2863378 2273510..2275957 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2292; hyaluronate lyase precursor 2 2275957 2863378 SAS2103 Staphylococcus aureus subsp. aureus MSSA476 hyaluronate lyase precursor 2 YP_044213.1 2273510 D 282459 CDS YP_044214.1 49486993 2863846 2276146..2276571 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2295; hypothetical protein 2276571 2863846 SAS2104 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044214.1 2276146 D 282459 CDS YP_044215.1 49486994 2863847 complement(2276958..2277662) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2296; hypothetical protein 2277662 2863847 SAS2105 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044215.1 2276958 R 282459 CDS YP_044216.1 49486995 2863072 complement(2277699..2279363) 1 NC_002953.3 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase; acetolactate synthase 2279363 2863072 SAS2106 Staphylococcus aureus subsp. aureus MSSA476 acetolactate synthase YP_044216.1 2277699 R 282459 CDS YP_044217.1 49486996 2863073 2279611..2279736 1 NC_002953.3 Doubtful CDS; hypothetical protein 2279736 2863073 SAS2107 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044217.1 2279611 D 282459 CDS YP_044218.1 49486997 2863527 complement(2279810..2279992) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2297b; Doubtful CDS; hypothetical protein 2279992 2863527 SAS2107a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044218.1 2279810 R 282459 CDS YP_044220.1 49486999 2862183 complement(2280339..2280731) 1 NC_002953.3 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 2280731 rpsI 2862183 rpsI Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S9 YP_044220.1 2280339 R 282459 CDS YP_044221.1 49487000 2862184 complement(2280751..2281188) 1 NC_002953.3 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 2281188 rplM 2862184 rplM Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L13 YP_044221.1 2280751 R 282459 CDS YP_044222.1 49487001 2862293 complement(2281428..2282231) 1 NC_002953.3 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 2282231 truA 2862293 truA Staphylococcus aureus subsp. aureus MSSA476 tRNA pseudouridine synthase A YP_044222.1 2281428 R 282459 CDS YP_044223.1 49487002 2863438 complement(2282236..2283042) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2303; cobalt transport protein 2283042 2863438 SAS2111 Staphylococcus aureus subsp. aureus MSSA476 cobalt transport protein YP_044223.1 2282236 R 282459 CDS YP_044224.1 49487003 2863439 complement(2283032..2283892) 1 NC_002953.3 with CbiNQ forms the ABC transporter for cobalt import; Staphylococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2283892 cbiO 2863439 cbiO Staphylococcus aureus subsp. aureus MSSA476 cobalt transporter ATP-binding subunit YP_044224.1 2283032 R 282459 CDS YP_044225.1 49487004 2862708 complement(2283889..2284698) 1 NC_002953.3 with CbiNQ forms the ABC transporter for cobalt import; Staphylococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit 2284698 cbiO 2862708 cbiO Staphylococcus aureus subsp. aureus MSSA476 cobalt transporter ATP-binding subunit YP_044225.1 2283889 R 282459 CDS YP_044226.1 49487005 2862709 complement(2285236..2285604) 1 NC_002953.3 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 2285604 rplQ 2862709 rplQ Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L17 YP_044226.1 2285236 R 282459 CDS YP_044227.1 49487006 2863070 complement(2285621..2286565) 1 NC_002953.3 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 2286565 2863070 SAS2115 Staphylococcus aureus subsp. aureus MSSA476 DNA-directed RNA polymerase subunit alpha YP_044227.1 2285621 R 282459 CDS YP_044228.1 49487007 2863071 complement(2286640..2287029) 1 NC_002953.3 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 2287029 2863071 SAS2116 Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S11 YP_044228.1 2286640 R 282459 CDS YP_044229.1 49487008 2864153 complement(2287053..2287418) 1 NC_002953.3 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 2287418 rpsM 2864153 rpsM Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S13 YP_044229.1 2287053 R 282459 CDS YP_044230.1 49487009 2864154 complement(2287441..2287554) 1 NC_002953.3 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 2287554 rpmJ 2864154 rpmJ Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L36 YP_044230.1 2287441 R 282459 CDS YP_044231.1 49487010 2864062 complement(2287586..2287804) 1 NC_002953.3 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 2287804 infA 2864062 infA Staphylococcus aureus subsp. aureus MSSA476 translation initiation factor IF-1 YP_044231.1 2287586 R 282459 CDS YP_044232.1 49487011 2862441 complement(2287997..2288644) 1 NC_002953.3 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 2288644 adk 2862441 adk Staphylococcus aureus subsp. aureus MSSA476 adenylate kinase YP_044232.1 2287997 R 282459 CDS YP_044233.1 49487012 2862442 complement(2288661..2289953) 1 NC_002953.3 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 2289953 secY 2862442 secY Staphylococcus aureus subsp. aureus MSSA476 preprotein translocase subunit SecY YP_044233.1 2288661 R 282459 CDS YP_044234.1 49487013 2863336 complement(2289953..2290393) 1 NC_002953.3 late assembly protein; 50S ribosomal protein L15 2290393 rplO 2863336 rplO Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L15 YP_044234.1 2289953 R 282459 CDS YP_044235.1 49487014 2863337 complement(2290410..2290589) 1 NC_002953.3 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 2290589 rpmD 2863337 rpmD Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L30 YP_044235.1 2290410 R 282459 CDS YP_044236.1 49487015 2863384 complement(2290606..2291106) 1 NC_002953.3 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 2291106 rpsE 2863384 rpsE Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S5 YP_044236.1 2290606 R 282459 CDS YP_044237.1 49487016 2863385 complement(2291127..2291486) 1 NC_002953.3 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 2291486 rplR 2863385 rplR Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L18 YP_044237.1 2291127 R 282459 CDS YP_044238.1 49487017 2862391 complement(2291517..2292053) 1 NC_002953.3 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 2292053 rplF 2862391 rplF Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L6 YP_044238.1 2291517 R 282459 CDS YP_044239.1 49487018 2862392 complement(2292078..2292476) 1 NC_002953.3 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 2292476 rpsH 2862392 rpsH Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S8 YP_044239.1 2292078 R 282459 CDS YP_044240.1 49487019 2863479 complement(2292508..2292693) 1 NC_002953.3 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 2292693 rpsN 2863479 rpsN Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S14 YP_044240.1 2292508 R 282459 CDS YP_044241.1 49487020 2862269 complement(2292716..2293255) 1 NC_002953.3 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 2293255 rplE 2862269 rplE Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L5 YP_044241.1 2292716 R 282459 CDS YP_044242.1 49487021 2862270 complement(2293282..2293599) 1 NC_002953.3 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 2293599 rplX 2862270 rplX Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L24 YP_044242.1 2293282 R 282459 CDS YP_044243.1 49487022 2863244 complement(2293635..2294003) 1 NC_002953.3 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 2294003 rplN 2863244 rplN Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L14 YP_044243.1 2293635 R 282459 CDS YP_044244.1 49487023 2863245 complement(2294035..2294298) 1 NC_002953.3 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 2294298 rpsQ 2863245 rpsQ Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S17 YP_044244.1 2294035 R 282459 CDS YP_044245.1 49487024 2862822 complement(2294322..2294531) 1 NC_002953.3 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 2294531 2862822 SAS2133 Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L29 YP_044245.1 2294322 R 282459 CDS YP_044246.1 49487025 2862823 complement(2294521..2294955) 1 NC_002953.3 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 2294955 rplP 2862823 rplP Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L16 YP_044246.1 2294521 R 282459 CDS YP_044247.1 49487026 2863594 complement(2294958..2295611) 1 NC_002953.3 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 2295611 rpsC 2863594 rpsC Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S3 YP_044247.1 2294958 R 282459 CDS YP_044248.1 49487027 2863595 complement(2295635..2295988) 1 NC_002953.3 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 2295988 rplV 2863595 rplV Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L22 YP_044248.1 2295635 R 282459 CDS YP_044249.1 49487028 2863496 complement(2296017..2296295) 1 NC_002953.3 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 2296295 rpsS 2863496 rpsS Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S19 YP_044249.1 2296017 R 282459 CDS YP_044250.1 49487029 2862712 complement(2296362..2297195) 1 NC_002953.3 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 2297195 rplB 2862712 rplB Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L2 YP_044250.1 2296362 R 282459 CDS YP_044251.1 49487030 2862713 complement(2297228..2297503) 1 NC_002953.3 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 2297503 rplW 2862713 rplW Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L23 YP_044251.1 2297228 R 282459 CDS YP_044252.1 49487031 2863790 complement(2297503..2298126) 1 NC_002953.3 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 2298126 rplD 2863790 rplD Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L4 YP_044252.1 2297503 R 282459 CDS YP_044253.1 49487032 2863791 complement(2298153..2298815) 1 NC_002953.3 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 2298815 rplC 2863791 rplC Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L3 YP_044253.1 2298153 R 282459 CDS YP_044254.1 49487033 2862567 complement(2298843..2299151) 1 NC_002953.3 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 2299151 rpsJ 2862567 rpsJ Staphylococcus aureus subsp. aureus MSSA476 30S ribosomal protein S10 YP_044254.1 2298843 R 282459 CDS YP_044255.1 49487034 2862568 2299502..2299897 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2337; hypothetical protein 2299897 2862568 SAS2143 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044255.1 2299502 D 282459 CDS YP_044256.1 49487035 2863412 complement(2300088..2301422) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2338; xanthine/uracil permeases family protein 2301422 2863412 SAS2144 Staphylococcus aureus subsp. aureus MSSA476 xanthine/uracil permeases family protein YP_044256.1 2300088 R 282459 CDS YP_044257.1 49487036 2863413 complement(2301535..2303670) 1 NC_002953.3 decatenates replicating daughter chromosomes; DNA topoisomerase III 2303670 2863413 SAS2145 Staphylococcus aureus subsp. aureus MSSA476 DNA topoisomerase III YP_044257.1 2301535 R 282459 CDS YP_044258.1 49487037 2863920 2303857..2304744 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2340; acetyltransferase (GNAT) family protein 2304744 2863920 SAS2146 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase (GNAT) family protein YP_044258.1 2303857 D 282459 CDS YP_044259.1 49487038 2862799 2304925..2305788 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2341; glucose uptake protein 2305788 2862799 SAS2147 Staphylococcus aureus subsp. aureus MSSA476 glucose uptake protein YP_044259.1 2304925 D 282459 CDS YP_044260.1 49487039 2862800 complement(2306207..2307115) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2342; hypothetical protein 2307115 2862800 SAS2148 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044260.1 2306207 R 282459 CDS YP_044261.1 49487040 2863093 2307248..2307412 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2343; hypothetical protein 2307412 2863093 SAS2149 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044261.1 2307248 D 282459 CDS YP_044262.1 49487041 2863094 2307657..2307974 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2344; hypothetical protein 2307974 2863094 SAS2150 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044262.1 2307657 D 282459 CDS YP_044263.1 49487042 2862818 complement(2308158..2311325) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2345; AcrB/AcrD/AcrF family protein 2311325 2862818 SAS2151 Staphylococcus aureus subsp. aureus MSSA476 AcrB/AcrD/AcrF family protein YP_044263.1 2308158 R 282459 CDS YP_044264.1 49487043 2862819 complement(2311442..2312707) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2346; peptidoglycan pentaglycine interpeptide biosynthesis protein 2312707 2862819 SAS2152 Staphylococcus aureus subsp. aureus MSSA476 peptidoglycan pentaglycine interpeptide biosynthesis protein YP_044264.1 2311442 R 282459 CDS YP_044265.1 49487044 2863836 2313096..2313347 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2347; hypothetical protein 2313347 2863836 SAS2153 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044265.1 2313096 D 282459 CDS YP_044266.1 49487045 2863837 complement(2313339..2314103) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2348; hypothetical protein 2314103 2863837 SAS2154 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044266.1 2313339 R 282459 CDS YP_044267.1 49487046 2863060 2314265..2314705 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2349; MarR family transcriptional regulator 2314705 2863060 SAS2155 Staphylococcus aureus subsp. aureus MSSA476 MarR family transcriptional regulator YP_044267.1 2314265 D 282459 CDS YP_044268.1 49487047 2863786 2314698..2315909 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2350; transporter protein 2315909 2863786 SAS2156 Staphylococcus aureus subsp. aureus MSSA476 transporter protein YP_044268.1 2314698 D 282459 CDS YP_044269.1 49487048 2863787 complement(2316011..2316361) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2351; hypothetical protein 2316361 2863787 SAS2157 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044269.1 2316011 R 282459 CDS YP_044270.1 49487049 2862797 complement(2316939..2317961) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2352; molybdenum cofactor biosynthesis protein A 2317961 2862797 SAS2158 Staphylococcus aureus subsp. aureus MSSA476 molybdenum cofactor biosynthesis protein A YP_044270.1 2316939 R 282459 CDS YP_044271.1 49487050 2862798 complement(2317981..2318580) 1 NC_002953.3 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 2318580 mobA 2862798 mobA Staphylococcus aureus subsp. aureus MSSA476 molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_044271.1 2317981 R 282459 CDS YP_044272.1 49487051 2862788 complement(2318587..2318820) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2354; molybdopterin-synthase small subunit 2318820 2862788 SAS2160 Staphylococcus aureus subsp. aureus MSSA476 molybdopterin-synthase small subunit YP_044272.1 2318587 R 282459 CDS YP_044273.1 49487052 2862789 complement(2318826..2319272) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2355; molybdopterin-synthase large subunit 2319272 2862789 SAS2161 Staphylococcus aureus subsp. aureus MSSA476 molybdopterin-synthase large subunit YP_044273.1 2318826 R 282459 CDS YP_044274.1 49487053 2864179 complement(2319286..2319771) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2356; molybdopterin-guanine dinucleotide biosynthesis protein B 2319771 2864179 SAS2162 Staphylococcus aureus subsp. aureus MSSA476 molybdopterin-guanine dinucleotide biosynthesis protein B YP_044274.1 2319286 R 282459 CDS YP_044275.1 49487054 2864180 complement(2319768..2321027) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2357; molybdenum cofactor biosynthesis protein 2321027 2864180 SAS2163 Staphylococcus aureus subsp. aureus MSSA476 molybdenum cofactor biosynthesis protein YP_044275.1 2319768 R 282459 CDS YP_044276.1 49487055 2863493 2321090..2321584 1 NC_002953.3 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 2321584 moaC 2863493 moaC Staphylococcus aureus subsp. aureus MSSA476 molybdenum cofactor biosynthesis protein MoaC YP_044276.1 2321090 D 282459 CDS YP_044277.1 49487056 2862876 complement(2321586..2322092) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2359; molybdenum cofactor biosynthesis protein B 2322092 2862876 SAS2165 Staphylococcus aureus subsp. aureus MSSA476 molybdenum cofactor biosynthesis protein B YP_044277.1 2321586 R 282459 CDS YP_044278.1 49487057 2862877 complement(2322123..2323127) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2360; molybdopterin synthase sulfurylase 2323127 2862877 SAS2166 Staphylococcus aureus subsp. aureus MSSA476 molybdopterin synthase sulfurylase YP_044278.1 2322123 R 282459 CDS YP_044279.1 49487058 2862185 complement(2323297..2323902) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2361; molybdenum transport ATP-binding protein 2323902 2862185 SAS2167 Staphylococcus aureus subsp. aureus MSSA476 molybdenum transport ATP-binding protein YP_044279.1 2323297 R 282459 CDS YP_044280.1 49487059 2862186 complement(2323903..2324574) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2362; molybdenum transport system permease 2324574 2862186 SAS2168 Staphylococcus aureus subsp. aureus MSSA476 molybdenum transport system permease YP_044280.1 2323903 R 282459 CDS YP_044281.1 49487060 2862882 complement(2324588..2325370) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2363; molybdate-binding lipoprotein precursor 2325370 2862882 SAS2169 Staphylococcus aureus subsp. aureus MSSA476 molybdate-binding lipoprotein precursor YP_044281.1 2324588 R 282459 CDS YP_044282.1 49487061 2862883 2325660..2326457 1 NC_002953.3 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 2326457 2862883 SAS2170 Staphylococcus aureus subsp. aureus MSSA476 formate dehydrogenase accessory protein YP_044282.1 2325660 D 282459 CDS YP_044283.1 49487062 2864350 complement(2326629..2327399) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2365; acetyltransferase (GNAT) family protein 2327399 2864350 SAS2171 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase (GNAT) family protein YP_044283.1 2326629 R 282459 CDS YP_044284.1 49487063 2864351 complement(2327476..2328030) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2366; BioY family protein 2328030 2864351 SAS2172 Staphylococcus aureus subsp. aureus MSSA476 BioY family protein YP_044284.1 2327476 R 282459 CDS YP_044285.1 49487064 2862273 complement(2328151..2329092) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2367; inosine-uridine preferring nucleoside hydrolase 2329092 2862273 SAS2173 Staphylococcus aureus subsp. aureus MSSA476 inosine-uridine preferring nucleoside hydrolase YP_044285.1 2328151 R 282459 CDS YP_044286.1 49487065 2863629 complement(2329490..2330398) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2368; ferrichrome-binding lipoprotein precursor 2330398 2863629 SAS2174 Staphylococcus aureus subsp. aureus MSSA476 ferrichrome-binding lipoprotein precursor YP_044286.1 2329490 R 282459 CDS YP_044287.1 49487066 2863630 complement(2330612..2331766) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2369; hypothetical protein 2331766 2863630 SAS2175 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044287.1 2330612 R 282459 CDS YP_044288.1 49487067 2863731 complement(2331813..2331905) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2370; Doubtful CDS. No significant database hits; hypothetical protein 2331905 2863731 SAS2176 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044288.1 2331813 R 282459 CDS YP_044289.1 49487068 2863732 complement(2331983..2332888) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2371; hypothetical protein 2332888 2863732 SAS2177 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044289.1 2331983 R 282459 CDS YP_044290.1 49487069 2862009 2333148..2333450 1 NC_002953.3 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 2333450 ureA 2862009 ureA Staphylococcus aureus subsp. aureus MSSA476 urease subunit gamma YP_044290.1 2333148 D 282459 CDS YP_044291.1 49487070 2862010 2333464..2333874 1 NC_002953.3 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Staphylococcus saprophyticus plays a role in bladder invasiveness and may induce the formation of kidney and bladder stones due to the alkalization of urine; urease subunit beta 2333874 ureB 2862010 ureB Staphylococcus aureus subsp. aureus MSSA476 urease subunit beta YP_044291.1 2333464 D 282459 CDS YP_044292.1 49487071 2862157 2333871..2335586 1 NC_002953.3 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 2335586 ureC 2862157 ureC Staphylococcus aureus subsp. aureus MSSA476 urease subunit alpha YP_044292.1 2333871 D 282459 CDS YP_044293.1 49487072 2862158 2335599..2336051 1 NC_002953.3 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 2336051 ureE 2862158 ureE Staphylococcus aureus subsp. aureus MSSA476 urease accessory protein UreE YP_044293.1 2335599 D 282459 CDS YP_044294.1 49487073 2862411 2336044..2336733 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2376; urease accessory protein UreF 2336733 2862411 SAS2182 Staphylococcus aureus subsp. aureus MSSA476 urease accessory protein UreF YP_044294.1 2336044 D 282459 CDS YP_044295.1 49487074 2863074 2336746..2337360 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2377; urease accessory protein UreG 2337360 2863074 SAS2183 Staphylococcus aureus subsp. aureus MSSA476 urease accessory protein UreG YP_044295.1 2336746 D 282459 CDS YP_044296.1 49487075 2863075 2337360..2338196 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2378; urease accessory protein UreD 2338196 2863075 SAS2184 Staphylococcus aureus subsp. aureus MSSA476 urease accessory protein UreD YP_044296.1 2337360 D 282459 CDS YP_044297.1 49487076 2863376 complement(2338385..2338732) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2379; accessory regulator A 2338732 2863376 SAS2185 Staphylococcus aureus subsp. aureus MSSA476 accessory regulator A YP_044297.1 2338385 R 282459 CDS YP_044298.1 49487077 2863377 complement(2339160..2339486) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2380; hypothetical protein 2339486 2863377 SAS2186 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044298.1 2339160 R 282459 CDS YP_044299.1 49487078 2863405 complement(2339550..2340293) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2381; hypothetical protein 2340293 2863405 SAS2187 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044299.1 2339550 R 282459 CDS YP_044300.1 49487079 2863406 complement(2340320..2342275) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2382; transcriptional regulator 2342275 2863406 SAS2188 Staphylococcus aureus subsp. aureus MSSA476 transcriptional regulator YP_044300.1 2340320 R 282459 CDS YP_044301.1 49487080 2862014 2342885..2343694 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2383; hypothetical protein 2343694 2862014 SAS2189 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044301.1 2342885 D 282459 CDS YP_044302.1 49487081 2862015 complement(2343711..2343932) 1 NC_002953.3 Doubtful CDS. No significant database hits; hypothetical protein 2343932 2862015 SAS2190 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044302.1 2343711 R 282459 CDS YP_044303.1 49487082 2863294 complement(2344127..2345527) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2385; Na+/H+ antiporter 2345527 2863294 SAS2191 Staphylococcus aureus subsp. aureus MSSA476 Na+/H+ antiporter YP_044303.1 2344127 R 282459 CDS YP_044304.1 49487083 2863792 complement(2345622..2346704) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2386; dehydrogenase 2346704 2863792 SAS2192 Staphylococcus aureus subsp. aureus MSSA476 dehydrogenase YP_044304.1 2345622 R 282459 CDS YP_044305.1 49487084 2863793 2346952..2347374 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2387; hypothetical protein 2347374 2863793 SAS2193 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044305.1 2346952 D 282459 CDS YP_044306.1 49487085 2864433 2347611..2348111 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2388; hypothetical protein 2348111 2864433 SAS2194 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044306.1 2347611 D 282459 CDS YP_044307.1 49487086 2864434 2348207..2348416 1 NC_002953.3 Doubtful CDS. No significant database matches; hypothetical protein 2348416 2864434 SAS2195 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044307.1 2348207 D 282459 CDS YP_044308.1 49487087 2863150 2348473..2349426 1 NC_002953.3 Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; glycerate dehydrogenase 2349426 2863150 SAS2196 Staphylococcus aureus subsp. aureus MSSA476 glycerate dehydrogenase YP_044308.1 2348473 D 282459 CDS YP_044309.1 49487088 2863151 complement(2349507..2350631) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2390; hypothetical protein 2350631 2863151 SAS2197 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044309.1 2349507 R 282459 CDS YP_044310.1 49487089 2863148 complement(2351356..2352132) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2391; N-acetylmuramoyl-L-alanine amidase 2352132 2863148 SAS2198 Staphylococcus aureus subsp. aureus MSSA476 N-acetylmuramoyl-L-alanine amidase YP_044310.1 2351356 R 282459 CDS YP_044311.1 49487090 2863149 complement(2352154..2352405) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2391a; Weakly similar to Clostridium acetobutylicum predicted membrane protein cac2051 SWALL:Q97HG0 (EMBL:AE007708) (92 aa) fasta scores: E(): 6.9, 25.35% id in 71 aa; hypothetical protein 2352405 2863149 SAS2199 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044311.1 2352154 R 282459 CDS YP_044312.1 49487091 2863907 complement(2352615..2353088) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2392; hypothetical protein 2353088 2863907 SAS2200 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044312.1 2352615 R 282459 CDS YP_044313.1 49487092 2863871 complement(2353088..2356042) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2393; bifunctional protein GlmU 2356042 2863871 SAS2201 Staphylococcus aureus subsp. aureus MSSA476 bifunctional protein GlmU YP_044313.1 2353088 R 282459 CDS YP_044314.1 49487093 2863963 complement(2356644..2357591) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2394; hypothetical protein 2357591 2863963 SAS2202 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044314.1 2356644 R 282459 CDS YP_044315.1 49487094 2862177 complement(2357724..2358521) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2395; inositol monophosphatase 2358521 2862177 SAS2203 Staphylococcus aureus subsp. aureus MSSA476 inositol monophosphatase YP_044315.1 2357724 R 282459 CDS YP_044316.1 49487095 2862178 2358906..2359598 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2396; DeoR family regulatory protein 2359598 2862178 SAS2204 Staphylococcus aureus subsp. aureus MSSA476 DeoR family regulatory protein YP_044316.1 2358906 D 282459 CDS YP_044317.1 49487096 2862087 complement(2360245..2360982) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2397; hypothetical protein 2360982 2862087 SAS2206 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044317.1 2360245 R 282459 CDS YP_044318.1 49487097 2862801 2361031..2361360 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2398; hypothetical protein 2361360 2862801 SAS2207 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044318.1 2361031 D 282459 CDS YP_044319.1 49487098 2862802 2361805..2362677 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2399; transcriptional regulator 2362677 2862802 SAS2208 Staphylococcus aureus subsp. aureus MSSA476 transcriptional regulator YP_044319.1 2361805 D 282459 CDS YP_044320.1 49487099 2861958 complement(2363064..2364443) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2400; amino acid permease 2364443 2861958 SAS2209 Staphylococcus aureus subsp. aureus MSSA476 amino acid permease YP_044320.1 2363064 R 282459 CDS YP_044321.1 49487100 2863507 2364723..2365079 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2401; hypothetical protein 2365079 2863507 SAS2210 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044321.1 2364723 D 282459 CDS YP_044322.1 49487101 2863508 2365076..2365261 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2402; hypothetical protein 2365261 2863508 SAS2211 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044322.1 2365076 D 282459 CDS YP_044323.1 49487102 2861778 complement(2365357..2365548) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2403; hypothetical protein 2365548 2861778 SAS2212 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044323.1 2365357 R 282459 CDS YP_044324.1 49487103 2861779 complement(2365559..2366194) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2404; haloacid dehalogenase 2366194 2861779 SAS2213 Staphylococcus aureus subsp. aureus MSSA476 haloacid dehalogenase YP_044324.1 2365559 R 282459 CDS YP_044325.1 49487104 2862648 complement(2366269..2367186) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2405; sodium/bile acid symporter family protein 2367186 2862648 SAS2214 Staphylococcus aureus subsp. aureus MSSA476 sodium/bile acid symporter family protein YP_044325.1 2366269 R 282459 CDS YP_044326.1 49487105 2862649 2367454..2367984 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2407; hypothetical protein 2367984 2862649 SAS2215 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044326.1 2367454 D 282459 CDS YP_044327.1 49487106 2863965 complement(2368050..2369654) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2408; PTS system, arbutin-like IIBC component 2369654 2863965 SAS2216 Staphylococcus aureus subsp. aureus MSSA476 PTS system, arbutin-like IIBC component YP_044327.1 2368050 R 282459 CDS YP_044328.1 49487107 2863966 2369984..2370748 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2409; transcriptional regulator 2370748 2863966 SAS2217 Staphylococcus aureus subsp. aureus MSSA476 transcriptional regulator YP_044328.1 2369984 D 282459 CDS YP_044329.1 49487108 2862663 complement(2370806..2371312) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2410; hypothetical protein 2371312 2862663 SAS2218 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044329.1 2370806 R 282459 CDS YP_044330.1 49487109 2862732 complement(2371479..2372858) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2411; transporter 2372858 2862732 SAS2219 Staphylococcus aureus subsp. aureus MSSA476 transporter YP_044330.1 2371479 R 282459 CDS YP_044331.1 49487110 2862733 complement(2373017..2373586) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2412; hypothetical protein 2373586 2862733 SAS2220 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044331.1 2373017 R 282459 CDS YP_044332.1 49487111 2861771 complement(2374073..2374954) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2413; short chain dehydrogenase 2374954 2861771 SAS2221 Staphylococcus aureus subsp. aureus MSSA476 short chain dehydrogenase YP_044332.1 2374073 R 282459 CDS YP_044333.1 49487112 2861772 complement(2375065..2376186) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2414; peptidase 2376186 2861772 SAS2222 Staphylococcus aureus subsp. aureus MSSA476 peptidase YP_044333.1 2375065 R 282459 CDS YP_044334.1 49487113 2862702 complement(2376462..2377700) 1 NC_002953.3 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase 2377700 2862702 SAS2223 Staphylococcus aureus subsp. aureus MSSA476 imidazolonepropionase YP_044334.1 2376462 R 282459 CDS YP_044335.1 49487114 2862703 complement(2377700..2379361) 1 NC_002953.3 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 2379361 2862703 SAS2224 Staphylococcus aureus subsp. aureus MSSA476 urocanate hydratase YP_044335.1 2377700 R 282459 CDS YP_044336.1 49487115 2861851 2379521..2380405 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2418; LysR family regulatory protein 2380405 2861851 SAS2225 Staphylococcus aureus subsp. aureus MSSA476 LysR family regulatory protein YP_044336.1 2379521 D 282459 CDS YP_044337.1 49487116 2861852 complement(2380898..2381833) 1 NC_002953.3 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate; formimidoylglutamase 2381833 2861852 SAS2226 Staphylococcus aureus subsp. aureus MSSA476 formimidoylglutamase YP_044337.1 2380898 R 282459 CDS YP_044338.1 49487117 2862610 2382123..2383382 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2421; hypothetical protein 2383382 2862610 SAS2227 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044338.1 2382123 D 282459 CDS YP_044339.1 49487118 2862790 complement(2383448..2384134) 1 NC_002953.3 catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 2384134 2862790 SAS2228 Staphylococcus aureus subsp. aureus MSSA476 ribose-5-phosphate isomerase A YP_044339.1 2383448 R 282459 CDS YP_044340.1 49487119 2862791 2384308..2384961 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2423; hypothetical protein 2384961 2862791 SAS2229 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044340.1 2384308 D 282459 CDS YP_044341.1 49487120 2862181 complement(2385197..2386216) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2424; aldose 1-epimerase 2386216 2862181 SAS2230 Staphylococcus aureus subsp. aureus MSSA476 aldose 1-epimerase YP_044341.1 2385197 R 282459 CDS YP_044342.1 49487121 2862182 complement(2386246..2386572) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2425; hypothetical protein 2386572 2862182 SAS2231 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044342.1 2386246 R 282459 CDS YP_044343.1 49487122 2863400 complement(2386790..2388022) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2426; hypothetical protein 2388022 2863400 SAS2232 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044343.1 2386790 R 282459 CDS YP_044344.1 49487123 2863401 complement(2388015..2388914) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2427; ABC transporter ATP-binding protein 2388914 2863401 SAS2233 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_044344.1 2388015 R 282459 CDS YP_044345.1 49487124 2863898 complement(2389145..2389765) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2428; hypothetical protein 2389765 2863898 SAS2234 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044345.1 2389145 R 282459 CDS YP_044346.1 49487125 2863899 2389757..2389879 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2428a; Doubtful CDS; hypothetical protein 2389879 2863899 SAS2234a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044346.1 2389757 D 282459 CDS YP_044347.1 49487126 3248052 2389945..2390076 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2428b; Doubtful CDS; hypothetical protein 2390076 3248052 SAS2234b Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044347.1 2389945 D 282459 CDS YP_044348.1 49487127 2863908 2390164..2390772 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2429; 3-methylpurine glycosylase 2390772 2863908 SAS2235 Staphylococcus aureus subsp. aureus MSSA476 3-methylpurine glycosylase YP_044348.1 2390164 D 282459 CDS YP_044349.1 49487128 2862228 2391109..2392317 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2430; permease 2392317 2862228 SAS2236 Staphylococcus aureus subsp. aureus MSSA476 permease YP_044349.1 2391109 D 282459 CDS YP_044350.1 49487129 2862229 complement(2392365..2393414) 1 NC_002953.3 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 2393414 2862229 SAS2237 Staphylococcus aureus subsp. aureus MSSA476 isopentenyl pyrophosphate isomerase YP_044350.1 2392365 R 282459 CDS YP_044351.1 49487130 2863788 complement(2393445..2394392) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2432; CorA-like Mg2+ transporter protein 2394392 2863788 SAS2238 Staphylococcus aureus subsp. aureus MSSA476 CorA-like Mg2+ transporter protein YP_044351.1 2393445 R 282459 CDS YP_044352.1 49487131 2863789 2394489..2394980 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2433; hypothetical protein 2394980 2863789 SAS2239 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044352.1 2394489 D 282459 CDS YP_044353.1 49487132 2862409 2394977..2395396 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2434; hypothetical protein 2395396 2862409 SAS2240 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044353.1 2394977 D 282459 CDS YP_044354.1 49487133 2862410 complement(2395504..2396424) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2435; hypothetical protein 2396424 2862410 SAS2241 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044354.1 2395504 R 282459 CDS YP_044355.1 49487134 2862784 2396632..2397270 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2436; hypothetical protein 2397270 2862784 SAS2242 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044355.1 2396632 D 282459 CDS YP_044356.1 49487135 2862785 complement(2397516..2399447) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2437; transporter 2399447 2862785 SAS2243 Staphylococcus aureus subsp. aureus MSSA476 transporter YP_044356.1 2397516 R 282459 CDS YP_044357.1 49487136 2862337 complement(2399460..2400107) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2438; hypothetical protein 2400107 2862337 SAS2244 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044357.1 2399460 R 282459 CDS YP_044358.1 49487137 2863991 2400228..2400779 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2439; TetR family regulatory protein 2400779 2863991 SAS2245 Staphylococcus aureus subsp. aureus MSSA476 TetR family regulatory protein YP_044358.1 2400228 D 282459 CDS YP_044359.1 49487138 2863992 complement(2401009..2402217) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2441; teicoplanin resistance associated membrane protein 2402217 2863992 SAS2246 Staphylococcus aureus subsp. aureus MSSA476 teicoplanin resistance associated membrane protein YP_044359.1 2401009 R 282459 CDS YP_044360.1 49487139 2863995 complement(2402486..2403868) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2442; teicoplanin resistance associated membrane protein 2403868 2863995 SAS2247 Staphylococcus aureus subsp. aureus MSSA476 teicoplanin resistance associated membrane protein YP_044360.1 2402486 R 282459 CDS YP_044361.1 49487140 2863996 complement(2404108..2404563) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2443; MarR family transcriptional regulator 2404563 2863996 SAS2248 Staphylococcus aureus subsp. aureus MSSA476 MarR family transcriptional regulator YP_044361.1 2404108 R 282459 CDS YP_044362.1 49487141 2863152 2404758..2405726 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2444; hypothetical protein 2405726 2863152 SAS2249 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044362.1 2404758 D 282459 CDS YP_044363.1 49487142 2863153 complement(2405957..2406622) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2445; ABC transporter ATP-binding protein 2406622 2863153 SAS2250 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_044363.1 2405957 R 282459 CDS YP_044364.1 49487143 2864003 complement(2406622..2407677) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2446; permease 2407677 2864003 SAS2251 Staphylococcus aureus subsp. aureus MSSA476 permease YP_044364.1 2406622 R 282459 CDS YP_044365.1 49487144 2864004 2407813..2408487 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2447; response regulator protein 2408487 2864004 SAS2252 Staphylococcus aureus subsp. aureus MSSA476 response regulator protein YP_044365.1 2407813 D 282459 CDS YP_044366.1 49487145 2863760 2408480..2409853 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2448; sensor kinase 2409853 2863760 SAS2253 Staphylococcus aureus subsp. aureus MSSA476 sensor kinase YP_044366.1 2408480 D 282459 CDS YP_044367.1 49487146 2862284 2410016..2410459 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2449; hypothetical protein 2410459 2862284 SAS2254 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044367.1 2410016 D 282459 CDS YP_044368.1 49487147 2862285 2410456..2410911 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2450; hypothetical protein 2410911 2862285 SAS2255 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044368.1 2410456 D 282459 CDS YP_044369.1 49487148 2862251 complement(2410977..2412512) 1 NC_002953.3 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 2412512 2862251 SAS2256 Staphylococcus aureus subsp. aureus MSSA476 malate:quinone oxidoreductase YP_044369.1 2410977 R 282459 CDS YP_044370.1 49487149 2862252 complement(2412836..2414434) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2455; L-lactate permease 2 2414434 2862252 SAS2257 Staphylococcus aureus subsp. aureus MSSA476 L-lactate permease 2 YP_044370.1 2412836 R 282459 CDS YP_044371.1 49487150 2862253 2414751..2416424 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2456; hypothetical protein 2416424 2862253 SAS2258 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044371.1 2414751 D 282459 CDS YP_044372.1 49487151 2862608 complement(2416578..2417192) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2457; hypothetical protein 2417192 2862608 SAS2259 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044372.1 2416578 R 282459 CDS YP_044373.1 49487152 2863435 complement(2417506..2418021) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2458; acetyltransferase (GNAT) family protein 2418021 2863435 SAS2260 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase (GNAT) family protein YP_044373.1 2417506 R 282459 CDS YP_044374.1 49487153 2863436 2418212..2419216 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2459; zinc-binding dehydrogenase 2419216 2863436 SAS2261 Staphylococcus aureus subsp. aureus MSSA476 zinc-binding dehydrogenase YP_044374.1 2418212 D 282459 CDS YP_044375.1 49487154 2863308 2419459..2420706 1 NC_002953.3 hypothetical protein 2420706 2863308 SAS2262 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044375.1 2419459 D 282459 CDS YP_044376.1 49487155 2863309 complement(2420982..2421383) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2460; acetyltransferase (GNAT) family protein 2421383 2863309 SAS2263 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase (GNAT) family protein YP_044376.1 2420982 R 282459 CDS YP_044377.1 49487156 2863032 complement(2421419..2422453) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2461; pyridine nucleotide-disulfide oxidoreductase family protein 2422453 2863032 SAS2264 Staphylococcus aureus subsp. aureus MSSA476 pyridine nucleotide-disulfide oxidoreductase family protein YP_044377.1 2421419 R 282459 CDS YP_044378.1 49487157 2862874 complement(2422685..2423116) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2462; hypothetical protein 2423116 2862874 SAS2265 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044378.1 2422685 R 282459 CDS YP_044379.1 49487158 2862875 complement(2423323..2424600) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2463; hypothetical protein 2424600 2862875 SAS2266 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044379.1 2423323 R 282459 CDS YP_044380.1 49487159 2862124 2424761..2425384 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2464; TetR family regulatory protein 2425384 2862124 SAS2267 Staphylococcus aureus subsp. aureus MSSA476 TetR family regulatory protein YP_044380.1 2424761 D 282459 CDS YP_044381.1 49487160 2862125 2425430..2426374 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2465; CorA-like Mg2+ transporter protein 2426374 2862125 SAS2268 Staphylococcus aureus subsp. aureus MSSA476 CorA-like Mg2+ transporter protein YP_044381.1 2425430 D 282459 CDS YP_044382.1 49487161 2863516 complement(2426459..2427901) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2466; PTS system, sucrose-specific IIBC component 2427901 2863516 SAS2269 Staphylococcus aureus subsp. aureus MSSA476 PTS system, sucrose-specific IIBC component YP_044382.1 2426459 R 282459 CDS YP_044383.1 49487162 2864394 2428084..2428467 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2467; hypothetical protein 2428467 2864394 SAS2270 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044383.1 2428084 D 282459 CDS YP_044384.1 49487163 2862243 2429955..2432060 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2468; AraC family transcriptional regulator 2432060 2862243 SAS2271 Staphylococcus aureus subsp. aureus MSSA476 AraC family transcriptional regulator YP_044384.1 2429955 D 282459 CDS YP_044385.1 49487164 2862244 2432131..2432553 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2469; hypothetical protein 2432553 2862244 SAS2272 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044385.1 2432131 D 282459 CDS YP_044386.1 49487165 2864330 2432818..2433174 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2470; hypothetical protein 2433174 2864330 SAS2273 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044386.1 2432818 D 282459 CDS YP_044387.1 49487166 2864331 complement(2433445..2434722) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2472; proton/sodium-glutamate symport protein 2434722 2864331 SAS2274 Staphylococcus aureus subsp. aureus MSSA476 proton/sodium-glutamate symport protein YP_044387.1 2433445 R 282459 CDS YP_044388.1 49487167 2862544 complement(2434904..2435269) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2473; hypothetical protein 2435269 2862544 SAS2275 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044388.1 2434904 R 282459 CDS YP_044389.1 49487168 2863745 2435667..2436113 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2474; MarR family transcriptional regulator 2436113 2863745 SAS2276 Staphylococcus aureus subsp. aureus MSSA476 MarR family transcriptional regulator YP_044389.1 2435667 D 282459 CDS YP_044390.1 49487169 2863746 2436335..2436757 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2475; small heat shock protein 2436757 2863746 SAS2277 Staphylococcus aureus subsp. aureus MSSA476 small heat shock protein YP_044390.1 2436335 D 282459 CDS YP_044391.1 49487170 2864132 complement(2436864..2438033) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2476; nitrite transport protein 2438033 2864132 SAS2278 Staphylococcus aureus subsp. aureus MSSA476 nitrite transport protein YP_044391.1 2436864 R 282459 CDS YP_044392.1 49487171 2864133 2438104..2438223 1 NC_002953.3 Doubtful CDS; hypothetical protein 2438223 2864133 SAS2278a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044392.1 2438104 D 282459 CDS YP_044393.1 49487172 2862859 2439296..2440036 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2478; MerR family transcriptional regulator 2440036 2862859 SAS2281 Staphylococcus aureus subsp. aureus MSSA476 MerR family transcriptional regulator YP_044393.1 2439296 D 282459 CDS YP_044394.1 49487173 2862600 complement(2440294..2440947) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2480; response regulator 2440947 2862600 SAS2282 Staphylococcus aureus subsp. aureus MSSA476 response regulator YP_044394.1 2440294 R 282459 CDS YP_044395.1 49487174 2862601 complement(2440970..2442004) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2481; histidine kinase 2442004 2862601 SAS2283 Staphylococcus aureus subsp. aureus MSSA476 histidine kinase YP_044395.1 2440970 R 282459 CDS YP_044396.1 49487175 2863447 complement(2442028..2442480) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2482; hypothetical protein 2442480 2863447 SAS2284 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044396.1 2442028 R 282459 CDS YP_044397.1 49487176 2863448 complement(2442500..2443177) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2483; nitrate reductase gamma chain 2443177 2863448 SAS2285 Staphylococcus aureus subsp. aureus MSSA476 nitrate reductase gamma chain YP_044397.1 2442500 R 282459 CDS YP_044398.1 49487177 2863145 complement(2443170..2443745) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2484; respiratory nitrate reductase delta chain 2443745 2863145 SAS2286 Staphylococcus aureus subsp. aureus MSSA476 respiratory nitrate reductase delta chain YP_044398.1 2443170 R 282459 CDS YP_044399.1 49487178 2863080 complement(2443738..2445297) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2485; nitrate reductase subunit beta 2445297 2863080 SAS2287 Staphylococcus aureus subsp. aureus MSSA476 nitrate reductase subunit beta YP_044399.1 2443738 R 282459 CDS YP_044400.1 49487179 2863081 complement(2445287..2448976) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2486; nitrate reductase subunit alpha 2448976 2863081 SAS2288 Staphylococcus aureus subsp. aureus MSSA476 nitrate reductase subunit alpha YP_044400.1 2445287 R 282459 CDS YP_044401.1 49487180 2862864 complement(2449284..2450261) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2487; tetrapyrrole (corrin/porphyrin) methylase family protein 2450261 2862864 SAS2289 Staphylococcus aureus subsp. aureus MSSA476 tetrapyrrole (corrin/porphyrin) methylase family protein YP_044401.1 2449284 R 282459 CDS YP_044402.1 49487181 2862865 complement(2450252..2450566) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2488; assimilatory nitrite reductase small subunit 2450566 2862865 SAS2290 Staphylococcus aureus subsp. aureus MSSA476 assimilatory nitrite reductase small subunit YP_044402.1 2450252 R 282459 CDS YP_044403.1 49487182 2862866 complement(2450570..2452975) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2489; nitrite reductase large subunit 2452975 2862866 SAS2291 Staphylococcus aureus subsp. aureus MSSA476 nitrite reductase large subunit YP_044403.1 2450570 R 282459 CDS YP_044404.1 49487183 2863773 complement(2453041..2453772) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2490; hypothetical protein 2453772 2863773 SAS2292 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044404.1 2453041 R 282459 CDS YP_044405.1 49487184 2863369 complement(2454001..2454528) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2491; acetyltransferase (GNAT) family protein 2454528 2863369 SAS2293 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase (GNAT) family protein YP_044405.1 2454001 R 282459 CDS YP_044406.1 49487185 2863370 complement(2454772..2455596) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2493; nitrite transporter 2455596 2863370 SAS2294 Staphylococcus aureus subsp. aureus MSSA476 nitrite transporter YP_044406.1 2454772 R 282459 CDS YP_044407.1 49487186 2864017 complement(2455813..2455995) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2494; hypothetical protein 2455995 2864017 SAS2295 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044407.1 2455813 R 282459 CDS YP_044408.1 49487187 2864018 complement(2456079..2456546) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2495; hypothetical protein 2456546 2864018 SAS2296 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044408.1 2456079 R 282459 CDS YP_044409.1 49487188 2863289 complement(2456732..2458282) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2496; solute binding lipoprotein 2458282 2863289 SAS2297 Staphylococcus aureus subsp. aureus MSSA476 solute binding lipoprotein YP_044409.1 2456732 R 282459 CDS YP_044410.1 49487189 2863518 complement(2458576..2458842) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2497; hypothetical protein 2458842 2863518 SAS2298 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044410.1 2458576 R 282459 CDS YP_044411.1 49487190 2863519 complement(2458842..2459093) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2498; hypothetical protein 2459093 2863519 SAS2299 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044411.1 2458842 R 282459 CDS YP_044412.1 49487191 2862455 complement(2459366..2459965) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2499; lipoprotein 2459965 2862455 SAS2300 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_044412.1 2459366 R 282459 CDS YP_044413.1 49487192 2862456 complement(2459984..2460346) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2500; lipoprotein 2460346 2862456 SAS2301 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_044413.1 2459984 R 282459 CDS YP_044414.1 49487193 2862457 2460601..2461851 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2501; FemAB family protein 2461851 2862457 SAS2302 Staphylococcus aureus subsp. aureus MSSA476 FemAB family protein YP_044414.1 2460601 D 282459 CDS YP_044415.1 49487194 2864098 complement(2461948..2462679) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2502; ABC transporter ATP-binding protein 2462679 2864098 SAS2303 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_044415.1 2461948 R 282459 CDS YP_044416.1 49487195 2864444 complement(2462676..2463395) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2503; transport system membrane protein 2463395 2864444 SAS2304 Staphylococcus aureus subsp. aureus MSSA476 transport system membrane protein YP_044416.1 2462676 R 282459 CDS YP_044417.1 49487196 2864445 complement(2463376..2464155) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2504; extracellular solute-binding lipoprotein 2464155 2864445 SAS2305 Staphylococcus aureus subsp. aureus MSSA476 extracellular solute-binding lipoprotein YP_044417.1 2463376 R 282459 CDS YP_044418.1 49487197 2863225 complement(2464276..2465715) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2505; transport system protein 2465715 2863225 SAS2306 Staphylococcus aureus subsp. aureus MSSA476 transport system protein YP_044418.1 2464276 R 282459 CDS YP_044419.1 49487198 2863226 complement(2466147..2466833) 1 NC_002953.3 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 2466833 gpmA 2863226 gpmA Staphylococcus aureus subsp. aureus MSSA476 phosphoglyceromutase YP_044419.1 2466147 R 282459 CDS YP_044420.1 49487199 2862260 complement(2467160..2468026) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2507; cation efflux family protein 2468026 2862260 SAS2308 Staphylococcus aureus subsp. aureus MSSA476 cation efflux family protein YP_044420.1 2467160 R 282459 CDS YP_044421.1 49487200 2863247 2468724..2470037 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2508; IgG-binding protein 2470037 2863247 SAS2309 Staphylococcus aureus subsp. aureus MSSA476 IgG-binding protein YP_044421.1 2468724 D 282459 CDS YP_044422.1 49487201 2863248 2470573..2471502 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2509; gamma-hemolysin component A precursor 2471502 2863248 SAS2310 Staphylococcus aureus subsp. aureus MSSA476 gamma-hemolysin component A precursor YP_044422.1 2470573 D 282459 CDS YP_044423.1 49487202 2863252 2472070..2473017 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2510; gamma-hemolysin component C precursor 2473017 2863252 SAS2311 Staphylococcus aureus subsp. aureus MSSA476 gamma-hemolysin component C precursor YP_044423.1 2472070 D 282459 CDS YP_044424.1 49487203 2863253 2473019..2473996 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2511; gamma-hemolysin component C precursor 2473996 2863253 SAS2312 Staphylococcus aureus subsp. aureus MSSA476 gamma-hemolysin component C precursor YP_044424.1 2473019 D 282459 CDS YP_044425.1 49487204 2863254 complement(2474048..2474515) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2512; hypothetical protein 2474515 2863254 SAS2313 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044425.1 2474048 R 282459 CDS YP_044426.1 49487205 2862677 complement(2474526..2475218) 1 NC_002953.3 catalyzes the formation of pimeloyl-CoA from pimelate and coenzyme A; 6-carboxyhexanoate--CoA ligase 2475218 2862677 SAS2314 Staphylococcus aureus subsp. aureus MSSA476 6-carboxyhexanoate--CoA ligase YP_044426.1 2474526 R 282459 CDS YP_044427.1 49487206 2863312 complement(2475229..2476344) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2514; 8-amino-7-oxononanoate synthase 2476344 2863312 SAS2315 Staphylococcus aureus subsp. aureus MSSA476 8-amino-7-oxononanoate synthase YP_044427.1 2475229 R 282459 CDS YP_044428.1 49487207 2863313 complement(2476322..2477329) 1 NC_002953.3 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine; biotin synthase 2477329 2863313 SAS2316 Staphylococcus aureus subsp. aureus MSSA476 biotin synthase YP_044428.1 2476322 R 282459 CDS YP_044429.1 49487208 2864252 complement(2477331..2478689) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2516; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 2478689 2864252 SAS2317 Staphylococcus aureus subsp. aureus MSSA476 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_044429.1 2477331 R 282459 CDS YP_044430.1 49487209 2864253 complement(2478667..2479353) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2517; dethiobiotin synthetase 2479353 2864253 SAS2318 Staphylococcus aureus subsp. aureus MSSA476 dethiobiotin synthetase YP_044430.1 2478667 R 282459 CDS YP_044431.1 49487210 2861866 complement(2479806..2481539) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2518; ABC transporter ATP-binding protein 2481539 2861866 SAS2319 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_044431.1 2479806 R 282459 CDS YP_044432.1 49487211 2863596 complement(2481564..2483348) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2519; ABC transporter ATP-binding protein 2483348 2863596 SAS2320 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_044432.1 2481564 R 282459 CDS YP_044433.1 49487212 2863597 complement(2483877..2483984) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2519a; Doubtful CDS; hypothetical protein 2483984 2863597 SAS2320a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044433.1 2483877 R 282459 CDS YP_044434.1 49487213 2864195 2484015..2484269 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2520; hypothetical protein 2484269 2864195 SAS2322 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044434.1 2484015 D 282459 CDS YP_044435.1 49487214 2864196 complement(2484252..2484638) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2521; hypothetical protein 2484638 2864196 SAS2323 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044435.1 2484252 R 282459 CDS YP_044436.1 49487215 2864197 2484896..2486038 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2522; glycerate kinase 2486038 2864197 SAS2324 Staphylococcus aureus subsp. aureus MSSA476 glycerate kinase YP_044436.1 2484896 D 282459 CDS YP_044437.1 49487216 2863101 2486098..2486757 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2523; hypothetical protein 2486757 2863101 SAS2325 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044437.1 2486098 D 282459 CDS YP_044438.1 49487217 2864309 2486939..2488150 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2524; transporter protein 2488150 2864309 SAS2326 Staphylococcus aureus subsp. aureus MSSA476 transporter protein YP_044438.1 2486939 D 282459 CDS YP_044439.1 49487218 2864310 complement(2488273..2488746) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2525; hypothetical protein 2488746 2864310 SAS2327 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044439.1 2488273 R 282459 CDS YP_044440.1 49487219 2863678 2488859..2489515 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2526; hypothetical protein 2489515 2863678 SAS2328 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044440.1 2488859 D 282459 CDS YP_044441.1 49487220 2863679 complement(2489578..2490384) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2527; hypothetical protein 2490384 2863679 SAS2329 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044441.1 2489578 R 282459 CDS YP_044442.1 49487221 2861810 2490670..2492079 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2528; amino acid permease 2492079 2861810 SAS2330 Staphylococcus aureus subsp. aureus MSSA476 amino acid permease YP_044442.1 2490670 D 282459 CDS YP_044443.1 49487222 2863019 2492217..2494295 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2529; sodium/hydrogen exchanger family protein 2494295 2863019 SAS2331 Staphylococcus aureus subsp. aureus MSSA476 sodium/hydrogen exchanger family protein YP_044443.1 2492217 D 282459 CDS YP_044444.1 49487223 2863020 complement(2494435..2496264) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2530; hypothetical protein 2496264 2863020 SAS2332 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044444.1 2494435 R 282459 CDS YP_044445.1 49487224 2863488 2496496..2497992 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2531; hypothetical protein 2497992 2863488 SAS2333 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044445.1 2496496 D 282459 CDS YP_044446.1 49487225 2863489 complement(2498084..2498935) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2532; hypothetical protein 2498935 2863489 SAS2334 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044446.1 2498084 R 282459 CDS YP_044447.1 49487226 2863490 complement(2499257..2500192) 1 NC_002953.3 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 2500192 2863490 SAS2335 Staphylococcus aureus subsp. aureus MSSA476 2-dehydropantoate 2-reductase YP_044447.1 2499257 R 282459 CDS YP_044448.1 49487227 2862731 complement(2500418..2501818) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2534; transport protein 2501818 2862731 SAS2336 Staphylococcus aureus subsp. aureus MSSA476 transport protein YP_044448.1 2500418 R 282459 CDS YP_044449.1 49487228 2863735 complement(2502112..2502807) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2535; glycine betaine/carnitine/choline transport system permease 2502807 2863735 SAS2337 Staphylococcus aureus subsp. aureus MSSA476 glycine betaine/carnitine/choline transport system permease YP_044449.1 2502112 R 282459 CDS YP_044450.1 49487229 2863736 complement(2502807..2503748) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2536; glycine betaine/carnitine/choline-binding lipoprotein precursor 2503748 2863736 SAS2338 Staphylococcus aureus subsp. aureus MSSA476 glycine betaine/carnitine/choline-binding lipoprotein precursor YP_044450.1 2502807 R 282459 CDS YP_044451.1 49487230 2863332 complement(2503765..2504400) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2537; glycine betaine/carnitine/choline transport system permease 2504400 2863332 SAS2339 Staphylococcus aureus subsp. aureus MSSA476 glycine betaine/carnitine/choline transport system permease YP_044451.1 2503765 R 282459 CDS YP_044452.1 49487231 2863219 complement(2504397..2505623) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2538; glycine betaine/carnitine/choline transport ATP-binding protein 2505623 2863219 SAS2340 Staphylococcus aureus subsp. aureus MSSA476 glycine betaine/carnitine/choline transport ATP-binding protein YP_044452.1 2504397 R 282459 CDS YP_044453.1 49487232 2863833 complement(2506293..2506892) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2539; hypothetical protein 2506892 2863833 SAS2341 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044453.1 2506293 R 282459 CDS YP_044454.1 49487233 2863741 2507072..2508709 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2540; amino acid permease 2508709 2863741 SAS2342 Staphylococcus aureus subsp. aureus MSSA476 amino acid permease YP_044454.1 2507072 D 282459 CDS YP_044455.1 49487234 2863742 2509016..2510368 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2541; carboxylesterase 2510368 2863742 SAS2343 Staphylococcus aureus subsp. aureus MSSA476 carboxylesterase YP_044455.1 2509016 D 282459 CDS YP_044456.1 49487235 2863475 complement(2510430..2511617) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2542; transport protein 2511617 2863475 SAS2344 Staphylococcus aureus subsp. aureus MSSA476 transport protein YP_044456.1 2510430 R 282459 CDS YP_044457.1 49487236 2863476 complement(2512013..2512789) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2543; hypothetical protein 2512789 2863476 SAS2345 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044457.1 2512013 R 282459 CDS YP_044458.1 49487237 2863477 complement(2512782..2513444) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2544; ABC transporter ATP-binding protein 2513444 2863477 SAS2346 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_044458.1 2512782 R 282459 CDS YP_044459.1 49487238 2863543 complement(2513692..2514768) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2545; hypothetical protein 2514768 2863543 SAS2347 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044459.1 2513692 R 282459 CDS YP_044460.1 49487239 2861780 complement(2515124..2515390) 1 NC_002953.3 Similar to Nitrosomonas europaea hypothetical protein ne1352 SWALL:Q82UW6 (EMBL:BX321860) (86 aa) fasta scores: E(): 4.4e-06, 36.9% id in 84 aa, and to Rickettsia sibirica hypothetical protein rsib_orf.415 SWALL:EAA25654 (EMBL:AABW01000001) (86 aa) fasta scores: E(): 2.7e-05, 37.64% id in 85 aa; hypothetical protein 2515390 2861780 SAS2348 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044460.1 2515124 R 282459 CDS YP_044461.1 49487240 2861781 complement(2515390..2515647) 1 NC_002953.3 Similar to Rickettsia sibirica hypothetical protein rsib_orf.416 SWALL:EAA25655 (EMBL:AABW01000001) (80 aa) fasta scores: E(): 4.4e-05, 35.36% id in 82 aa, and to Synechococcus sp. WH 8102 hypothetical protein synw0576 SWALL:CAE07091 (EMBL:BX569690) (80 aa) fasta scores: E(): 0.00013, 38.46% id in 78 aa; hypothetical protein 2515647 2861781 SAS2349 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044461.1 2515390 R 282459 CDS YP_044462.1 49487241 2863747 2516006..2516461 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2546; lipoprotein 2516461 2863747 SAS2350 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_044462.1 2516006 D 282459 CDS YP_044463.1 49487242 2863748 complement(2516629..2518206) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2547; hypothetical protein 2518206 2863748 SAS2351 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044463.1 2516629 R 282459 CDS YP_044464.1 49487243 2864367 2518402..2519151 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2548; hypothetical protein 2519151 2864367 SAS2352 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044464.1 2518402 D 282459 CDS YP_044465.1 49487244 2863513 complement(2519300..2519425) 1 NC_002953.3 Doubtful CDS; hypothetical protein 2519425 2863513 SAS2352a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044465.1 2519300 R 282459 CDS YP_044466.1 49487245 2863514 complement(2519513..2520706) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2549; transporter 2520706 2863514 SAS2353 Staphylococcus aureus subsp. aureus MSSA476 transporter YP_044466.1 2519513 R 282459 CDS YP_044467.1 49487246 2862462 complement(2520718..2521467) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2550; oligopeptide transporter ATPase 2521467 2862462 SAS2354 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transporter ATPase YP_044467.1 2520718 R 282459 CDS YP_044468.1 49487247 2862463 complement(2521460..2522275) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2551; oligopeptide transporter ATPase 2522275 2862463 SAS2355 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transporter ATPase YP_044468.1 2521460 R 282459 CDS YP_044469.1 49487248 2862464 complement(2522272..2523141) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2552; oligopeptide transporter membrane permease 2523141 2862464 SAS2356 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transporter membrane permease YP_044469.1 2522272 R 282459 CDS YP_044470.1 49487249 2863600 complement(2523138..2524073) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2553; oligopeptide transporter membrane permease 2524073 2863600 SAS2357 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transporter membrane permease YP_044470.1 2523138 R 282459 CDS YP_044471.1 49487250 2863601 complement(2524086..2525684) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2554; oligopeptide transporter substrate binding protein 2525684 2863601 SAS2358 Staphylococcus aureus subsp. aureus MSSA476 oligopeptide transporter substrate binding protein YP_044471.1 2524086 R 282459 CDS YP_044472.1 49487251 2863602 complement(2525824..2527128) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2555; hypothetical protein 2527128 2863602 SAS2359 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044472.1 2525824 R 282459 CDS YP_044473.1 49487252 2863078 complement(2527121..2527939) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2556; hypothetical protein 2527939 2863078 SAS2360 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044473.1 2527121 R 282459 CDS YP_044474.1 49487253 2863079 complement(2527950..2528771) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2557; hypothetical protein 2528771 2863079 SAS2361 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044474.1 2527950 R 282459 CDS YP_044475.1 49487254 2863967 complement(2529646..2530008) 1 NC_002953.3 Poor database matches. Weakly similar to Helicobacter pylori hypothetical protein HP0060 SWALL:O24900 (EMBL:AE000528) (813 aa) fasta scores: E(): 1.9, 29.8% id in 104 aa; hypothetical protein 2530008 2863967 SAS2362 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044475.1 2529646 R 282459 CDS YP_044476.1 49487255 2863320 complement(2530271..2531089) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2559; short chain dehydrogenase 2531089 2863320 SAS2363 Staphylococcus aureus subsp. aureus MSSA476 short chain dehydrogenase YP_044476.1 2530271 R 282459 CDS YP_044477.1 49487256 2863129 2531324..2532862 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2560; transporter 2532862 2863129 SAS2364 Staphylococcus aureus subsp. aureus MSSA476 transporter YP_044477.1 2531324 D 282459 CDS YP_044478.1 49487257 2863133 complement(2532974..2533396) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2561; hypothetical protein 2533396 2863133 SAS2365 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044478.1 2532974 R 282459 CDS YP_044479.1 49487258 2863134 complement(2533848..2534267) 1 NC_002953.3 hypothetical protein 2534267 2863134 SAS2366 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044479.1 2533848 R 282459 CDS YP_044480.1 49487259 2863135 complement(2534285..2534704) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2563; hypothetical protein 2534704 2863135 SAS2367 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044480.1 2534285 R 282459 CDS YP_044481.1 49487260 2863136 complement(2534731..2535141) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2565; hypothetical protein 2535141 2863136 SAS2368 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044481.1 2534731 R 282459 CDS YP_044482.1 49487261 2863417 complement(2535409..2535831) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2566; hypothetical protein 2535831 2863417 SAS2369 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044482.1 2535409 R 282459 CDS YP_044483.1 49487262 2863418 complement(2536082..2536777) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2567; short chain dehydrogenase 2536777 2863418 SAS2370 Staphylococcus aureus subsp. aureus MSSA476 short chain dehydrogenase YP_044483.1 2536082 R 282459 CDS YP_044484.1 49487263 2862727 2537066..2537347 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2568; hypothetical protein 2537347 2862727 SAS2371 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044484.1 2537066 D 282459 CDS YP_044485.1 49487264 2862728 complement(2537607..2537798) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2569; hypothetical protein 2537798 2862728 SAS2372 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044485.1 2537607 R 282459 CDS YP_044486.1 49487265 2863132 complement(2538338..2539153) 1 NC_002953.3 hypothetical protein 2539153 2863132 SAS2373 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044486.1 2538338 R 282459 CDS YP_044487.1 49487266 2863973 complement(2539267..2540085) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2570; hypothetical protein 2540085 2863973 SAS2374 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044487.1 2539267 R 282459 CDS YP_044488.1 49487267 2863974 complement(2540200..2540961) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2573; lipoprotein 2540961 2863974 SAS2375 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_044488.1 2540200 R 282459 CDS YP_044489.1 49487268 2863613 complement(2541264..2544125) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2574; helicase 2544125 2863613 SAS2376 Staphylococcus aureus subsp. aureus MSSA476 helicase YP_044489.1 2541264 R 282459 CDS YP_044490.1 49487269 2863614 complement(2544127..2544519) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2575; NUDIX hydrolase 2544519 2863614 SAS2377 Staphylococcus aureus subsp. aureus MSSA476 NUDIX hydrolase YP_044490.1 2544127 R 282459 CDS YP_044491.1 49487270 2863615 2544801..2546459 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2576; phosphomannomutase 2546459 2863615 SAS2378 Staphylococcus aureus subsp. aureus MSSA476 phosphomannomutase YP_044491.1 2544801 D 282459 CDS YP_044492.1 49487271 2863414 2546743..2547009 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2577; hypothetical protein 2547009 2863414 SAS2379 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044492.1 2546743 D 282459 CDS YP_044493.1 49487272 2863892 2547153..2547461 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2578; hypothetical protein 2547461 2863892 SAS2380 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044493.1 2547153 D 282459 CDS YP_044494.1 49487273 2863893 complement(2547569..2547802) 1 NC_002953.3 Poor database matches. Weakly similar to Anabaena sp. hypothetical protein asr3368 SWALL:Q8YRS5 (EMBL:AP003592) (75 aa) fasta scores: E(): 5.3, 24.61% id in 65 aa; hypothetical protein 2547802 2863893 SAS2381 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044494.1 2547569 R 282459 CDS YP_044495.1 49487274 2862523 complement(2547783..2548976) 1 NC_002953.3 Weakly similar to Enterococcus sp. 130, Staphylococcus aureus, Streptococcus intermedius, Streptococcus salivarius, Streptococcus sp. 6, and Streptococcus pneumoniae macrolide efflux protein E MefA or MefE SWALL:P95835 (EMBL:AY071835) (405 aa) fasta scores: E(): 2.7e-10, 22.22% id in 387 aa, and to Oceanobacillus iheyensis hypothetical conserved protein ob3168 SWALL:Q8ELQ1 (EMBL:AP004604) (401 aa) fasta scores: E(): 3.8e-20, 22.9% id in 393 aa; hypothetical protein 2548976 2862523 SAS2382 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044495.1 2547783 R 282459 CDS YP_044496.1 49487275 2862524 complement(2549359..2553474) 1 NC_002953.3 N-terminal region is similar to an internal region Staphylococcus aureus methicillin-resistant surface protein precursor Pls SWALL:MRSP_STAAU (SWALL:P80544) (1637 aa) fasta scores: E(): 1.2e-173, 55.06% id in 1037 aa; cell wall-anchored protein 2553474 2862524 SAS2383 Staphylococcus aureus subsp. aureus MSSA476 cell wall-anchored protein YP_044496.1 2549359 R 282459 CDS YP_044497.1 49487276 2863612 complement(2553779..2554138) 1 NC_002953.3 Similar to Staphylococcus aureus Staphylococcal accessory regulator SarA SWALL:Q53777 (EMBL:U46541) (113 aa) fasta scores: E(): 3.2e-09, 34.21% id in 114 aa, and to the N-terminal region of Clostridium perfringens probable transcriptional regulator cpe0789 SWALL:Q8XMA1 (EMBL:AP003188) (147 aa) fasta scores: E(): 0.12, 28.2% id in 117 aa; accessory regulator 2554138 2863612 SAS2384 Staphylococcus aureus subsp. aureus MSSA476 accessory regulator YP_044497.1 2553779 R 282459 CDS YP_044498.1 49487277 2863925 2554459..2555202 1 NC_002953.3 Almost identical to Staphylococcus aureus Rot-like protein Rlp SWALL:Q9EZK4 (EMBL:AF288788) (247 aa) fasta scores: E(): 8.2e-90, 99.59% id in 247 aa. Similar to N-terminal region of Staphylococcus aureus staphylococcal accessory regulator A homolog SarR SWALL:Q9F0R1 (EMBL:AF207701) (115 aa) fasta scores: E(): 0.0028, 27.77% id in 108 aa; accessory regulator 2555202 2863925 SAS2385 Staphylococcus aureus subsp. aureus MSSA476 accessory regulator YP_044498.1 2554459 D 282459 CDS YP_044499.1 49487278 2863926 complement(2555414..2556280) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2579; UTP--glucose-1-phosphate uridylyltransferase 2556280 2863926 SAS2386 Staphylococcus aureus subsp. aureus MSSA476 UTP--glucose-1-phosphate uridylyltransferase YP_044499.1 2555414 R 282459 CDS YP_044500.1 49487279 2862071 complement(2556460..2559333) 1 NC_002953.3 Similar to Staphylococcus aureus fibronectin-binding protein precursor FnbA SWALL:FNBA_STAAU (SWALL:P14738) (1018 aa) fasta scores: E(): 1.5e-103, 66.95% id in 1026 aa; fibronectin-binding protein precursor 2559333 fnbB 2862071 fnbB Staphylococcus aureus subsp. aureus MSSA476 fibronectin-binding protein precursor YP_044500.1 2556460 R 282459 CDS YP_044501.1 49487280 2862815 complement(2560014..2563061) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2580; fibronectin-binding protein precursor 2563061 2862815 SAS2388 Staphylococcus aureus subsp. aureus MSSA476 fibronectin-binding protein precursor YP_044501.1 2560014 R 282459 CDS YP_044502.1 49487281 2862816 complement(2563196..2563396) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2581; hypothetical protein 2563396 2862816 SAS2389 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044502.1 2563196 R 282459 CDS YP_044503.1 49487282 2862817 complement(2563530..2564888) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2582; gluconate permease 2564888 2862817 SAS2390 Staphylococcus aureus subsp. aureus MSSA476 gluconate permease YP_044503.1 2563530 R 282459 CDS YP_044504.1 49487283 2862779 complement(2565005..2566558) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2583; gluconokinase 2566558 2862779 SAS2391 Staphylococcus aureus subsp. aureus MSSA476 gluconokinase YP_044504.1 2565005 R 282459 CDS YP_044505.1 49487284 2862197 complement(2566582..2567262) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2584; gluconate operon transcriptional repressor 2567262 2862197 SAS2392 Staphylococcus aureus subsp. aureus MSSA476 gluconate operon transcriptional repressor YP_044505.1 2566582 R 282459 CDS YP_044506.1 49487285 2862198 complement(2567416..2568180) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2585; MerR family transcriptional regulator 2568180 2862198 SAS2393 Staphylococcus aureus subsp. aureus MSSA476 MerR family transcriptional regulator YP_044506.1 2567416 R 282459 CDS YP_044507.1 49487286 2863120 complement(2568345..2569037) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2586; hypothetical protein 2569037 2863120 SAS2394 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044507.1 2568345 R 282459 CDS YP_044508.1 49487287 2863121 complement(2569268..2569756) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2587; hypothetical protein 2569756 2863121 SAS2395 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044508.1 2569268 R 282459 CDS YP_044509.1 49487288 2863938 complement(2569823..2571646) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2588; hypothetical protein 2571646 2863938 SAS2396 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044509.1 2569823 R 282459 CDS YP_044510.1 49487289 2863807 complement(2572158..2572361) 1 NC_002953.3 Doubtful CDS; hypothetical protein 2572361 2863807 SAS2396a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044510.1 2572158 R 282459 CDS YP_044511.1 49487290 2863808 complement(2572555..2573832) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2589; transporter protein 2573832 2863808 SAS2397 Staphylococcus aureus subsp. aureus MSSA476 transporter protein YP_044511.1 2572555 R 282459 CDS YP_044512.1 49487291 2862247 2574379..2574990 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2590; DedA family protein 2574990 2862247 SAS2398 Staphylococcus aureus subsp. aureus MSSA476 DedA family protein YP_044512.1 2574379 D 282459 CDS YP_044513.1 49487292 2862248 2575508..2576203 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2594; ABC transporter ATP-binding protein 2576203 2862248 SAS2399 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_044513.1 2575508 D 282459 CDS YP_044514.1 49487293 2862249 2576205..2576975 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2595; hypothetical protein 2576975 2862249 SAS2400 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044514.1 2576205 D 282459 CDS YP_044515.1 49487294 2862503 2577349..2579313 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2596; hypothetical protein 2579313 2862503 SAS2401 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044515.1 2577349 D 282459 CDS YP_044517.1 49487296 2861991 2579655..2580734 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2597; hypothetical protein 2580734 2861991 SAS2402 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044517.1 2579655 D 282459 CDS YP_044518.1 49487297 2862624 complement(2580839..2581435) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2598; phospholipase/carboxylesterase 2581435 2862624 SAS2403 Staphylococcus aureus subsp. aureus MSSA476 phospholipase/carboxylesterase YP_044518.1 2580839 R 282459 CDS YP_044519.1 49487298 2862625 complement(2581463..2582422) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2599; dioxygenase 2582422 2862625 SAS2404 Staphylococcus aureus subsp. aureus MSSA476 dioxygenase YP_044519.1 2581463 R 282459 CDS YP_044520.1 49487299 2864178 complement(2582499..2582933) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2600; MarR family transcriptional regulator 2582933 2864178 SAS2405 Staphylococcus aureus subsp. aureus MSSA476 MarR family transcriptional regulator YP_044520.1 2582499 R 282459 CDS YP_044521.1 49487300 2862323 2583150..2583443 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2601; acetyltransferase (GNAT) family protein 2583443 2862323 SAS2406 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase (GNAT) family protein YP_044521.1 2583150 D 282459 CDS YP_044522.1 49487301 2862344 complement(2584543..2585214) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2603; nitroreductase family protein 2585214 2862344 SAS2409 Staphylococcus aureus subsp. aureus MSSA476 nitroreductase family protein YP_044522.1 2584543 R 282459 CDS YP_044523.1 49487302 2862345 2585484..2586476 1 NC_002953.3 catalyzes the formation of pyruvate from lactate; D-lactate dehydrogenase 2586476 2862345 SAS2410 Staphylococcus aureus subsp. aureus MSSA476 D-lactate dehydrogenase YP_044523.1 2585484 D 282459 CDS YP_044524.1 49487303 2862346 complement(2586723..2587523) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2607; haloacid dehalogenase 2587523 2862346 SAS2411 Staphylococcus aureus subsp. aureus MSSA476 haloacid dehalogenase YP_044524.1 2586723 R 282459 CDS YP_044525.1 49487304 2863761 2587844..2588479 1 NC_002953.3 Similar to Bacillus subtilis function unknown protein YydI SWALL:Q45593 (EMBL:D78193) (209 aa) fasta scores: E(): 1.3e-36, 61.42% id in 210 aa, and to Streptococcus agalactiae ABC transporter, ATP-binding protein sag2027 SWALL:Q8DX31 (EMBL:AE014283) (205 aa) fasta scores: E(): 1.9e-23, 44.01% id in 209 aa; ABC transporter ATP-binding protein 2588479 2863761 SAS2412 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_044525.1 2587844 D 282459 CDS YP_044526.1 49487305 2861996 2588485..2589216 1 NC_002953.3 Similar to Bacillus subtilis function unknown protein YydJ SWALL:Q45592 (EMBL:D78193) (240 aa) fasta scores: E(): 4.7e-56, 61.66% id in 240 aa, and to Streptococcus agalactiae membrane protein, sag2026 SWALL:Q8DX32 (EMBL:AE014283) (240 aa) fasta scores: E(): 2.3e-33, 42.97% id in 242 aa; hypothetical protein 2589216 2861996 SAS2413 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044526.1 2588485 D 282459 CDS YP_044527.1 49487306 2861997 complement(2589378..2589998) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2608; sortase 2589998 2861997 SAS2414 Staphylococcus aureus subsp. aureus MSSA476 sortase YP_044527.1 2589378 R 282459 CDS YP_044528.1 49487307 2864120 2590192..2590683 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2609; acetyltransferase (GNAT) family protein 2590683 2864120 SAS2415 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase (GNAT) family protein YP_044528.1 2590192 D 282459 CDS YP_044529.1 49487308 2864121 complement(2591249..2591419) 1 NC_002953.3 Doubtful CDS; hypothetical protein 2591419 2864121 SAS2415a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044529.1 2591249 R 282459 CDS YP_044530.1 49487309 2863759 complement(2591598..2592497) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2610; L-serine dehydratase subunit alpha 2592497 2863759 SAS2416 Staphylococcus aureus subsp. aureus MSSA476 L-serine dehydratase subunit alpha YP_044530.1 2591598 R 282459 CDS YP_044531.1 49487310 2862569 complement(2592511..2593191) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2611; L-serine dehydratase subunit beta 2593191 2862569 SAS2417 Staphylococcus aureus subsp. aureus MSSA476 L-serine dehydratase subunit beta YP_044531.1 2592511 R 282459 CDS YP_044532.1 49487311 2862570 complement(2593194..2594237) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2612; hypothetical protein 2594237 2862570 SAS2418 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044532.1 2593194 R 282459 CDS YP_044533.1 49487312 2862571 2594787..2594990 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2613; hypothetical protein 2594990 2862571 SAS2419 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044533.1 2594787 D 282459 CDS YP_044534.1 49487313 2863057 2595182..2596108 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2614; hypothetical protein 2596108 2863057 SAS2420 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044534.1 2595182 D 282459 CDS YP_044535.1 49487314 2864213 complement(2596189..2597157) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2615; hypothetical protein 2597157 2864213 SAS2421 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044535.1 2596189 R 282459 CDS YP_044536.1 49487315 2864214 complement(2597290..2597634) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2616; hypothetical protein 2597634 2864214 SAS2422 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044536.1 2597290 R 282459 CDS YP_044537.1 49487316 2862955 complement(2597676..2598086) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2617; hypothetical protein 2598086 2862955 SAS2423 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044537.1 2597676 R 282459 CDS YP_044538.1 49487317 2862956 complement(2598451..2600517) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2618; PTS system, glucose-specific IIABC component 2600517 2862956 SAS2424 Staphylococcus aureus subsp. aureus MSSA476 PTS system, glucose-specific IIABC component YP_044538.1 2598451 R 282459 CDS YP_044539.1 49487318 2862957 complement(2600818..2602557) 1 NC_002953.3 catalyzes the formation of acetyl phosphate from pyruvate; pyruvate oxidase 2602557 2862957 SAS2425 Staphylococcus aureus subsp. aureus MSSA476 pyruvate oxidase YP_044539.1 2600818 R 282459 CDS YP_044540.1 49487319 2864224 complement(2602604..2603293) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2620; hypothetical protein 2603293 2864224 SAS2426 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044540.1 2602604 R 282459 CDS YP_044541.1 49487320 2863766 complement(2603286..2603681) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2621; hypothetical protein 2603681 2863766 SAS2427 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044541.1 2603286 R 282459 CDS YP_044542.1 49487321 2863767 complement(2603894..2604772) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2622; LysR family regulatory protein 2604772 2863767 SAS2428 Staphylococcus aureus subsp. aureus MSSA476 LysR family regulatory protein YP_044542.1 2603894 R 282459 CDS YP_044543.1 49487322 2864249 2604939..2605157 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2623; hypothetical protein 2605157 2864249 SAS2429 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044543.1 2604939 D 282459 CDS YP_044544.1 49487323 2864250 2605547..2605978 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2624; hypothetical protein 2605978 2864250 SAS2430 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044544.1 2605547 D 282459 CDS YP_044545.1 49487324 2863821 complement(2606116..2607396) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2625; 3-hydroxy-3-methylglutaryl-CoA reductase 2607396 2863821 SAS2431 Staphylococcus aureus subsp. aureus MSSA476 3-hydroxy-3-methylglutaryl-CoA reductase YP_044545.1 2606116 R 282459 CDS YP_044546.1 49487325 2863822 2607650..2608816 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2626; 3-hydroxy-3-methylglutaryl-CoA synthase 2608816 2863822 SAS2432 Staphylococcus aureus subsp. aureus MSSA476 3-hydroxy-3-methylglutaryl-CoA synthase YP_044546.1 2607650 D 282459 CDS YP_044547.1 49487326 2863670 complement(2608986..2609507) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2627; 6-O-methylguanine DNA methyltransferase 2609507 2863670 SAS2433 Staphylococcus aureus subsp. aureus MSSA476 6-O-methylguanine DNA methyltransferase YP_044547.1 2608986 R 282459 CDS YP_044548.1 49487327 2862263 2609916..2612021 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2628; ATP-dependent protease ATP-binding subunit ClpL 2612021 2862263 SAS2434 Staphylococcus aureus subsp. aureus MSSA476 ATP-dependent protease ATP-binding subunit ClpL YP_044548.1 2609916 D 282459 CDS YP_044549.1 49487328 2862264 complement(2612090..2612260) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2629; hypothetical protein 2612260 2862264 SAS2435 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044549.1 2612090 R 282459 CDS YP_044550.1 49487329 2862265 complement(2612273..2614267) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2630; ferrous iron transport protein B 2614267 2862265 SAS2436 Staphylococcus aureus subsp. aureus MSSA476 ferrous iron transport protein B YP_044550.1 2612273 R 282459 CDS YP_044551.1 49487330 2861764 complement(2614279..2614506) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2631; hypothetical protein 2614506 2861764 SAS2437 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044551.1 2614279 R 282459 CDS YP_044552.1 49487331 2862986 complement(2614722..2617211) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2632; transport protein 2617211 2862986 SAS2438 Staphylococcus aureus subsp. aureus MSSA476 transport protein YP_044552.1 2614722 R 282459 CDS YP_044553.1 49487332 2862987 2617356..2617904 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2633; TetR family regulatory protein 2617904 2862987 SAS2439 Staphylococcus aureus subsp. aureus MSSA476 TetR family regulatory protein YP_044553.1 2617356 D 282459 CDS YP_044554.1 49487333 2863753 complement(2618259..2619803) 1 NC_002953.3 catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate; 1-pyrroline-5-carboxylate dehydrogenase 2619803 2863753 SAS2440 Staphylococcus aureus subsp. aureus MSSA476 1-pyrroline-5-carboxylate dehydrogenase YP_044554.1 2618259 R 282459 CDS YP_044555.1 49487334 2863754 complement(2619993..2620592) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2635; acetyltransferase 2620592 2863754 SAS2441 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase YP_044555.1 2619993 R 282459 CDS YP_044556.1 49487335 2863755 2620822..2621022 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2636; hypothetical protein 2621022 2863755 SAS2442 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044556.1 2620822 D 282459 CDS YP_044557.1 49487336 2863709 2621262..2623670 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2637; copper importing ATPase A 2623670 2863709 SAS2443 Staphylococcus aureus subsp. aureus MSSA476 copper importing ATPase A YP_044557.1 2621262 D 282459 CDS YP_044558.1 49487337 2861862 2624019..2624225 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2639; heavy-metal-associated protein 2624225 2861862 SAS2444 Staphylococcus aureus subsp. aureus MSSA476 heavy-metal-associated protein YP_044558.1 2624019 D 282459 CDS YP_044559.1 49487338 2861863 complement(2624315..2625313) 1 NC_002953.3 catalyzes the formation of pyruvate from lactate; D-lactate dehydrogenase 2625313 2861863 SAS2445 Staphylococcus aureus subsp. aureus MSSA476 D-lactate dehydrogenase YP_044559.1 2624315 R 282459 CDS YP_044560.1 49487339 2862843 complement(2625336..2626490) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2641; aminotransferase 2626490 2862843 SAS2446 Staphylococcus aureus subsp. aureus MSSA476 aminotransferase YP_044560.1 2625336 R 282459 CDS YP_044561.1 49487340 2862844 complement(2626917..2628425) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2642; squalene synthase 2628425 2862844 SAS2447 Staphylococcus aureus subsp. aureus MSSA476 squalene synthase YP_044561.1 2626917 R 282459 CDS YP_044562.1 49487341 2862845 complement(2628437..2629300) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2643; squalene desaturase 2629300 2862845 SAS2448 Staphylococcus aureus subsp. aureus MSSA476 squalene desaturase YP_044562.1 2628437 R 282459 CDS YP_044563.1 49487342 2862846 complement(2629337..2630464) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2645; glycosyl transferase 2630464 2862846 SAS2449 Staphylococcus aureus subsp. aureus MSSA476 glycosyl transferase YP_044563.1 2629337 R 282459 CDS YP_044564.1 49487343 2863716 complement(2630470..2631963) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2646; phytoene dehydrogenase related protein 2631963 2863716 SAS2450 Staphylococcus aureus subsp. aureus MSSA476 phytoene dehydrogenase related protein YP_044564.1 2630470 R 282459 CDS YP_044565.1 49487344 2863090 complement(2631956..2632453) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2647; hypothetical protein 2632453 2863090 SAS2451 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044565.1 2631956 R 282459 CDS YP_044566.1 49487345 2863091 complement(2632619..2633386) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2648; secretory antigen precursor 2633386 2863091 SAS2452 Staphylococcus aureus subsp. aureus MSSA476 secretory antigen precursor YP_044566.1 2632619 R 282459 CDS YP_044567.1 49487346 2863092 complement(2633747..2635558) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2649; hypothetical protein 2635558 2863092 SAS2453 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044567.1 2633747 R 282459 CDS YP_044568.1 49487347 2862097 complement(2636070..2636558) 1 NC_002953.3 Similar to Bacillus cereus iaa acetyltransferase bc4682 SWALL:Q816X8 (EMBL:AE017013) (163 aa) fasta scores: E(): 6.5e-19, 40.38% id in 156 aa, and to Bacillus subtilis protease synthase and sporulation negative regulatory protein Pai 1 PaiA or bsu32150 SWALL:PAIA_BACSU (SWALL:P21340) (171 aa) fasta scores: E(): 0.11, 24.28% id in 140 aa; acetyltransferase (GNAT) family protein 2636558 2862097 SAS2454 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase (GNAT) family protein YP_044568.1 2636070 R 282459 CDS YP_044569.1 49487348 2864272 complement(2636834..2637535) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2650; immunodominant antigen A 2637535 2864272 SAS2455 Staphylococcus aureus subsp. aureus MSSA476 immunodominant antigen A YP_044569.1 2636834 R 282459 CDS YP_044570.1 49487349 2864273 complement(2638143..2639198) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2651; hypothetical protein 2639198 2864273 SAS2456 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044570.1 2638143 R 282459 CDS YP_044571.1 49487350 2862764 2639344..2639547 1 NC_002953.3 hypothetical protein 2639547 2862764 SAS2457 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044571.1 2639344 D 282459 CDS YP_044572.1 49487351 2862765 2639608..2640177 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2652; TetR family regulatory protein 2640177 2862765 SAS2458 Staphylococcus aureus subsp. aureus MSSA476 TetR family regulatory protein YP_044572.1 2639608 D 282459 CDS YP_044573.1 49487352 2862766 2640375..2640875 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2653; hypothetical protein 2640875 2862766 SAS2459 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044573.1 2640375 D 282459 CDS YP_044574.1 49487353 2863635 2641095..2641325 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2654; hypothetical protein 2641325 2863635 SAS2460 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044574.1 2641095 D 282459 CDS YP_044575.1 49487354 2864088 complement(2641488..2641865) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2655; glyoxalase 2641865 2864088 SAS2461 Staphylococcus aureus subsp. aureus MSSA476 glyoxalase YP_044575.1 2641488 R 282459 CDS YP_044576.1 49487355 2864089 complement(2641882..2642703) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2656; hypothetical protein 2642703 2864089 SAS2462 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044576.1 2641882 R 282459 CDS YP_044577.1 49487356 2862910 complement(2642723..2643022) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2657; hypothetical protein 2643022 2862910 SAS2463 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044577.1 2642723 R 282459 CDS YP_044578.1 49487357 2862911 2643154..2643711 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2658; TetR family regulatory protein 2643711 2862911 SAS2464 Staphylococcus aureus subsp. aureus MSSA476 TetR family regulatory protein YP_044578.1 2643154 D 282459 CDS YP_044579.1 49487358 2864239 2643704..2644408 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2659; short chain dehydrogenase 2644408 2864239 SAS2465 Staphylococcus aureus subsp. aureus MSSA476 short chain dehydrogenase YP_044579.1 2643704 D 282459 CDS YP_044580.1 49487359 2864240 2644506..2645516 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2660; hypothetical protein 2645516 2864240 SAS2466 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044580.1 2644506 D 282459 CDS YP_044581.1 49487360 2862003 2645536..2646354 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2661; hydrolase 2646354 2862003 SAS2467 Staphylococcus aureus subsp. aureus MSSA476 hydrolase YP_044581.1 2645536 D 282459 CDS YP_044582.1 49487361 2864362 complement(2646501..2647391) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2662; cobalamin synthesis protein/P47K family protein 2647391 2864362 SAS2468 Staphylococcus aureus subsp. aureus MSSA476 cobalamin synthesis protein/P47K family protein YP_044582.1 2646501 R 282459 CDS YP_044583.1 49487362 2864363 complement(2647488..2648834) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2663; hypothetical protein 2648834 2864363 SAS2469 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044583.1 2647488 R 282459 CDS YP_044584.1 49487363 2864364 complement(2648822..2649928) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2664; hypothetical protein 2649928 2864364 SAS2470 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044584.1 2648822 R 282459 CDS YP_044585.1 49487364 2864232 complement(2650223..2650519) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2665; hypothetical protein 2650519 2864232 SAS2471 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044585.1 2650223 R 282459 CDS YP_044586.1 49487365 2863194 complement(2650507..2650875) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2666; hypothetical protein 2650875 2863194 SAS2472 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044586.1 2650507 R 282459 CDS YP_044587.1 49487366 2863195 complement(2650890..2651168) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2667; hypothetical protein 2651168 2863195 SAS2473 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044587.1 2650890 R 282459 CDS YP_044588.1 49487367 2862861 complement(2651507..2652373) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2668; hypothetical protein 2652373 2862861 SAS2474 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044588.1 2651507 R 282459 CDS YP_044589.1 49487368 2862862 2652591..2653655 1 NC_002953.3 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 2653655 2862862 SAS2475 Staphylococcus aureus subsp. aureus MSSA476 dihydroorotate dehydrogenase 2 YP_044589.1 2652591 D 282459 CDS YP_044590.1 49487369 2862863 2653810..2654085 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2670; hypothetical protein 2654085 2862863 SAS2476 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044590.1 2653810 D 282459 CDS YP_044591.1 49487370 2863737 complement(2654271..2654993) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2671; hypothetical protein 2654993 2863737 SAS2477 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044591.1 2654271 R 282459 CDS YP_044592.1 49487371 2863810 2655347..2655796 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2672; hypothetical protein 2655796 2863810 SAS2478 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044592.1 2655347 D 282459 CDS YP_044593.1 49487372 2863811 complement(2655877..2656464) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2673; DNA-binding protein 2656464 2863811 SAS2479 Staphylococcus aureus subsp. aureus MSSA476 DNA-binding protein YP_044593.1 2655877 R 282459 CDS YP_044594.1 49487373 2863315 2656607..2658289 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2674; hypothetical protein 2658289 2863315 SAS2480 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044594.1 2656607 D 282459 CDS YP_044595.1 49487374 2862155 complement(2659104..2659487) 1 NC_002953.3 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 2659487 2862155 SAS2482 Staphylococcus aureus subsp. aureus MSSA476 aspartate alpha-decarboxylase YP_044595.1 2659104 R 282459 CDS YP_044596.1 49487375 2862156 complement(2659489..2660340) 1 NC_002953.3 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 2660340 panC 2862156 panC Staphylococcus aureus subsp. aureus MSSA476 pantoate--beta-alanine ligase YP_044596.1 2659489 R 282459 CDS YP_044597.1 49487376 2861814 complement(2660333..2661151) 1 NC_002953.3 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 2661151 panB 2861814 panB Staphylococcus aureus subsp. aureus MSSA476 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_044597.1 2660333 R 282459 CDS YP_044598.1 49487377 2864046 2661224..2662084 1 NC_002953.3 catalyzes the formation of 2-dehydropantoate from (R)-pantoate; 2-dehydropantoate 2-reductase 2662084 2864046 SAS2485 Staphylococcus aureus subsp. aureus MSSA476 2-dehydropantoate 2-reductase YP_044598.1 2661224 D 282459 CDS YP_044599.1 49487378 2864047 complement(2662170..2662874) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2679; alpha-acetolactate decarboxylase 2662874 2864047 SAS2486 Staphylococcus aureus subsp. aureus MSSA476 alpha-acetolactate decarboxylase YP_044599.1 2662170 R 282459 CDS YP_044600.1 49487379 2864048 complement(2663152..2664111) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2680; L-lactate dehydrogenase 2 2664111 2864048 SAS2487 Staphylococcus aureus subsp. aureus MSSA476 L-lactate dehydrogenase 2 YP_044600.1 2663152 R 282459 CDS YP_044601.1 49487380 2862461 2664798..2666246 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2681; amino acid permease family protein 2666246 2862461 SAS2488 Staphylococcus aureus subsp. aureus MSSA476 amino acid permease family protein YP_044601.1 2664798 D 282459 CDS YP_044602.1 49487381 2864256 complement(2666326..2667669) 1 NC_002953.3 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 2667669 2864256 SAS2489 Staphylococcus aureus subsp. aureus MSSA476 4-aminobutyrate aminotransferase YP_044602.1 2666326 R 282459 CDS YP_044603.1 49487382 2864257 2667921..2668337 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2683; hypothetical protein 2668337 2864257 SAS2490 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044603.1 2667921 D 282459 CDS YP_044604.1 49487383 2864245 2668460..2669350 1 NC_002953.3 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis; fructose-1,6-bisphosphate aldolase 2669350 2864245 SAS2491 Staphylococcus aureus subsp. aureus MSSA476 fructose-1,6-bisphosphate aldolase YP_044604.1 2668460 D 282459 CDS YP_044605.1 49487384 2864246 complement(2669544..2671040) 1 NC_002953.3 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 2671040 2864246 SAS2492 Staphylococcus aureus subsp. aureus MSSA476 malate:quinone oxidoreductase YP_044605.1 2669544 R 282459 CDS YP_044606.1 49487385 2864247 2671465..2671665 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2686; hypothetical protein 2671665 2864247 SAS2493 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044606.1 2671465 D 282459 CDS YP_044607.1 49487386 2864173 complement(2671725..2673344) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2687; AMP-binding protein 2673344 2864173 SAS2494 Staphylococcus aureus subsp. aureus MSSA476 AMP-binding protein YP_044607.1 2671725 R 282459 CDS YP_044608.1 49487387 2864269 complement(2673517..2673960) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2688; hypothetical protein 2673960 2864269 SAS2495 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044608.1 2673517 R 282459 CDS YP_044609.1 49487388 2864270 complement(2674240..2674452) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2689; hypothetical protein 2674452 2864270 SAS2496 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044609.1 2674240 R 282459 CDS YP_044610.1 49487389 2864237 complement(2674730..2676439) 1 NC_002953.3 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 2676439 2864237 SAS2497 Staphylococcus aureus subsp. aureus MSSA476 choline dehydrogenase YP_044610.1 2674730 R 282459 CDS YP_044611.1 49487390 2864238 complement(2676700..2678190) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2691; betaine aldehyde dehydrogenase 2678190 2864238 SAS2498 Staphylococcus aureus subsp. aureus MSSA476 betaine aldehyde dehydrogenase YP_044611.1 2676700 R 282459 CDS YP_044612.1 49487391 2864165 2678440..2679006 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2692; hypothetical protein 2679006 2864165 SAS2499 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044612.1 2678440 D 282459 CDS YP_044613.1 49487392 2864166 complement(2679194..2679880) 1 NC_002953.3 Poor database matches. Weakly similar to the C-terminal region of Prochlorococcus marinus subsp. marinus str. CCMP1375 metallo-beta-lactamase superfamily hydrolase GloB or pro1462 SWALL:AAQ00506 (EMBL:AE017165) (300 aa) fasta scores: E(): 5.4e-05, 24% id in 200 aa; metallo-beta-lactamase superfamily protein 2679880 2864166 SAS2500 Staphylococcus aureus subsp. aureus MSSA476 metallo-beta-lactamase superfamily protein YP_044613.1 2679194 R 282459 CDS YP_044614.1 49487393 2862640 complement(2680139..2681761) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2693; choline transporter 2681761 2862640 SAS2501 Staphylococcus aureus subsp. aureus MSSA476 choline transporter YP_044614.1 2680139 R 282459 CDS YP_044615.1 49487394 2862477 complement(2682280..2682816) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2694; anaerobic ribonucleotide reductase activating protein 2682816 2862477 SAS2502 Staphylococcus aureus subsp. aureus MSSA476 anaerobic ribonucleotide reductase activating protein YP_044615.1 2682280 R 282459 CDS YP_044616.1 49487395 2862478 complement(2682813..2684663) 1 NC_002953.3 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 2684663 2862478 SAS2503 Staphylococcus aureus subsp. aureus MSSA476 anaerobic ribonucleoside triphosphate reductase YP_044616.1 2682813 R 282459 CDS YP_044617.1 49487396 2862479 complement(2684909..2686279) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2696; transporter protein 2686279 2862479 SAS2504 Staphylococcus aureus subsp. aureus MSSA476 transporter protein YP_044617.1 2684909 R 282459 CDS YP_044618.1 49487397 2863278 complement(2686755..2687360) 1 NC_002953.3 catalyzes the formation of siroheme from precorrin-2; precorrin-2 dehydrogenase 2687360 2863278 SAS2505 Staphylococcus aureus subsp. aureus MSSA476 precorrin-2 dehydrogenase YP_044618.1 2686755 R 282459 CDS YP_044619.1 49487398 2863317 complement(2687423..2689303) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2698; sulfite reductase [NADPH] flavoprotein alpha-component 2689303 2863317 SAS2506 Staphylococcus aureus subsp. aureus MSSA476 sulfite reductase [NADPH] flavoprotein alpha-component YP_044619.1 2687423 R 282459 CDS YP_044620.1 49487399 2863318 complement(2689698..2690195) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2699; glutathione peroxidase 2690195 2863318 SAS2507 Staphylococcus aureus subsp. aureus MSSA476 glutathione peroxidase YP_044620.1 2689698 R 282459 CDS YP_044621.1 49487400 2863738 complement(2691619..2693619) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2700; hypothetical protein 2693619 2863738 SAS2508 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044621.1 2691619 R 282459 CDS YP_044622.1 49487401 2863739 complement(2693616..2694371) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2701; ABC transporter ATP-binding protein 2694371 2863739 SAS2509 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_044622.1 2693616 R 282459 CDS YP_044623.1 49487402 2863740 complement(2694479..2695366) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2702; sensor kinase 2695366 2863740 SAS2510 Staphylococcus aureus subsp. aureus MSSA476 sensor kinase YP_044623.1 2694479 R 282459 CDS YP_044624.1 49487403 2863712 complement(2695377..2696042) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2703; response regulator protein 2696042 2863712 SAS2511 Staphylococcus aureus subsp. aureus MSSA476 response regulator protein YP_044624.1 2695377 R 282459 CDS YP_044625.1 49487404 2864130 complement(2696068..2696268) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2704; hypothetical protein 2696268 2864130 SAS2512 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044625.1 2696068 R 282459 CDS YP_044626.1 49487405 2864131 2696466..2697890 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2706; alkaline phosphatase III precursor 2697890 2864131 SAS2513 Staphylococcus aureus subsp. aureus MSSA476 alkaline phosphatase III precursor YP_044626.1 2696466 D 282459 CDS YP_044627.1 49487406 2862020 complement(2697950..2698051) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2706a; Doubtful CDS; hypothetical protein 2698051 2862020 SAS2513a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044627.1 2697950 R 282459 CDS YP_044628.1 49487407 2862021 complement(2698173..2698628) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2707; regulatory protein 2698628 2862021 SAS2514 Staphylococcus aureus subsp. aureus MSSA476 regulatory protein YP_044628.1 2698173 R 282459 CDS YP_044629.1 49487408 2864005 complement(2698873..2699634) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2708; esterase 2699634 2864005 SAS2515 Staphylococcus aureus subsp. aureus MSSA476 esterase YP_044629.1 2698873 R 282459 CDS YP_044630.1 49487409 2864006 complement(2699750..2702467) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2709; fibrinogen and keratin-10 binding surface anchored protein 2702467 2864006 SAS2516 Staphylococcus aureus subsp. aureus MSSA476 fibrinogen and keratin-10 binding surface anchored protein YP_044630.1 2699750 R 282459 CDS YP_044631.1 49487410 2862771 complement(2702817..2703521) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2710; regulatory protein 2703521 2862771 SAS2517 Staphylococcus aureus subsp. aureus MSSA476 regulatory protein YP_044631.1 2702817 R 282459 CDS YP_044632.2 161761282 2861848 complement(2703620..2704561) 1 NC_002953.3 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2704561 2861848 SAS2518 Staphylococcus aureus subsp. aureus MSSA476 carbamate kinase YP_044632.2 2703620 R 282459 CDS YP_044633.1 49487412 2861849 complement(2704578..2706014) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2712; arginine/ornithine antiporter 2706014 2861849 SAS2519 Staphylococcus aureus subsp. aureus MSSA476 arginine/ornithine antiporter YP_044633.1 2704578 R 282459 CDS YP_044634.1 49487413 2862126 complement(2706099..2707109) 1 NC_002953.3 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 2707109 2862126 SAS2520 Staphylococcus aureus subsp. aureus MSSA476 ornithine carbamoyltransferase YP_044634.1 2706099 R 282459 CDS YP_044635.1 49487414 2862406 complement(2707142..2708377) 1 NC_002953.3 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 2708377 2862406 SAS2521 Staphylococcus aureus subsp. aureus MSSA476 arginine deiminase YP_044635.1 2707142 R 282459 CDS YP_044636.1 49487415 2864235 complement(2708724..2709173) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2715; arginine repressor ArgR 2709173 2864235 SAS2522 Staphylococcus aureus subsp. aureus MSSA476 arginine repressor ArgR YP_044636.1 2708724 R 282459 CDS YP_044637.1 49487416 2864236 complement(2709540..2711069) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2716; zinc metalloproteinase aureolysin 2711069 2864236 SAS2523 Staphylococcus aureus subsp. aureus MSSA476 zinc metalloproteinase aureolysin YP_044637.1 2709540 R 282459 CDS YP_044638.1 49487417 2862643 complement(2711493..2712020) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2717; immunodominant antigen B 2712020 2862643 SAS2524 Staphylococcus aureus subsp. aureus MSSA476 immunodominant antigen B YP_044638.1 2711493 R 282459 CDS YP_044639.1 49487418 2862644 2712263..2712736 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2718; hypothetical protein 2712736 2862644 SAS2525 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044639.1 2712263 D 282459 CDS YP_044640.1 49487419 2862645 2712976..2714850 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2719; transcriptional regulator 2714850 2862645 SAS2526 Staphylococcus aureus subsp. aureus MSSA476 transcriptional regulator YP_044640.1 2712976 D 282459 CDS YP_044641.1 49487420 2863263 2714927..2716879 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2720; PTS transport system, IIABC component 2716879 2863263 SAS2527 Staphylococcus aureus subsp. aureus MSSA476 PTS transport system, IIABC component YP_044641.1 2714927 D 282459 CDS YP_044642.1 49487421 2862942 2716893..2717831 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2721; mannose-6-phosphate isomerase 2717831 2862942 SAS2528 Staphylococcus aureus subsp. aureus MSSA476 mannose-6-phosphate isomerase YP_044642.1 2716893 D 282459 CDS YP_044643.1 49487422 2862943 complement(2717943..2720924) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2722; hypothetical protein 2720924 2862943 SAS2529 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044643.1 2717943 R 282459 CDS YP_044644.1 49487423 2863779 2721135..2722994 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2723; N-acetylmuramoyl-L-alanine amidase 2722994 2863779 SAS2530 Staphylococcus aureus subsp. aureus MSSA476 N-acetylmuramoyl-L-alanine amidase YP_044644.1 2721135 D 282459 CDS YP_044645.1 49487424 2863598 complement(2723259..2723819) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2724; isochorismatase family protein 2723819 2863598 SAS2531 Staphylococcus aureus subsp. aureus MSSA476 isochorismatase family protein YP_044645.1 2723259 R 282459 CDS YP_044646.1 49487425 2863751 complement(2723988..2725895) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2725; surface anchored protein 2725895 2863751 SAS2532 Staphylococcus aureus subsp. aureus MSSA476 surface anchored protein YP_044646.1 2723988 R 282459 CDS YP_044647.1 49487426 2863752 complement(2726137..2727495) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2726; hypothetical protein 2727495 2863752 SAS2533 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044647.1 2726137 R 282459 CDS YP_044648.1 49487427 2864251 complement(2727488..2728996) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2727; hypothetical protein 2728996 2864251 SAS2534 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044648.1 2727488 R 282459 CDS YP_044649.1 49487428 2862044 complement(2729014..2731404) 1 NC_002953.3 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins; preprotein translocase subunit SecA 2731404 2862044 SAS2535 Staphylococcus aureus subsp. aureus MSSA476 preprotein translocase subunit SecA YP_044649.1 2729014 R 282459 CDS YP_044650.1 49487429 2862045 complement(2731394..2732353) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2729; hypothetical protein 2732353 2862045 SAS2536 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044650.1 2731394 R 282459 CDS YP_044651.1 49487430 2862046 complement(2732331..2733899) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2730; hypothetical protein 2733899 2862046 SAS2537 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044651.1 2732331 R 282459 CDS YP_044652.1 49487431 2862039 complement(2733889..2735442) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2731; hypothetical protein 2735442 2862039 SAS2538 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044652.1 2733889 R 282459 CDS YP_044653.1 49487432 2862211 complement(2735453..2736664) 1 NC_002953.3 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 2736664 secY 2862211 secY Staphylococcus aureus subsp. aureus MSSA476 preprotein translocase subunit SecY YP_044653.1 2735453 R 282459 CDS YP_044654.1 49487433 2862212 complement(2736794..2743621) 1 NC_002953.3 Similar to internal region of Streptococcus gordonii platelet binding protein GspB SWALL:Q939N5 (EMBL:AY028381) (3072 aa) fasta scores: E(): 3.4e-130, 42.3% id in 2234 aa, and to Lactobacillus plantarum cell surface SD repeat protein precursor Sdr or lp_1303.1 or lp_1303A SWALL:Q88XB6 (EMBL:AL935255) (3360 aa) fasta scores: E(): 8e-119, 42.16% id in 2196 aa; cell wall-anchored protein 2743621 2862212 SAS2540 Staphylococcus aureus subsp. aureus MSSA476 cell wall-anchored protein YP_044654.1 2736794 R 282459 CDS YP_044655.1 49487434 2862422 complement(2744166..2744858) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2735; hypothetical protein 2744858 2862422 SAS2541 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044655.1 2744166 R 282459 CDS YP_044656.1 49487435 2862423 2745171..2746115 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2736; lipoprotein 2746115 2862423 SAS2542 Staphylococcus aureus subsp. aureus MSSA476 lipoprotein YP_044656.1 2745171 D 282459 CDS YP_044657.1 49487436 2862424 2746102..2746404 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2738; hypothetical protein 2746404 2862424 SAS2543 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044657.1 2746102 D 282459 CDS YP_044658.1 49487437 2863809 2746558..2746917 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2739; hypothetical protein 2746917 2863809 SAS2544 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044658.1 2746558 D 282459 CDS YP_044659.1 49487438 2862100 complement(2747002..2747613) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2740; hypothetical protein 2747613 2862100 SAS2545 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044659.1 2747002 R 282459 CDS YP_044660.1 49487439 2862101 complement(2747692..2748168) 1 NC_002953.3 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; a fusion protein of this enzyme with MsrB provides protection against oxidative stress in Neisseria gonorrhoeae; methionine sulfoxide reductase A 2748168 2862101 SAS2546 Staphylococcus aureus subsp. aureus MSSA476 methionine sulfoxide reductase A YP_044660.1 2747692 R 282459 CDS YP_044661.1 49487440 2862329 complement(2748171..2748671) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2742; acetyltransferase (GNAT) family protein 2748671 2862329 SAS2547 Staphylococcus aureus subsp. aureus MSSA476 acetyltransferase (GNAT) family protein YP_044661.1 2748171 R 282459 CDS YP_044662.1 49487441 2862330 complement(2748906..2749673) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2743; capsule synthesis protein 2749673 2862330 SAS2548 Staphylococcus aureus subsp. aureus MSSA476 capsule synthesis protein YP_044662.1 2748906 R 282459 CDS YP_044663.1 49487442 2862514 complement(2749670..2750362) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2744; capsule synthesis protein 2750362 2862514 SAS2549 Staphylococcus aureus subsp. aureus MSSA476 capsule synthesis protein YP_044663.1 2749670 R 282459 CDS YP_044664.1 49487443 2862515 complement(2750379..2751041) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2745; capsule synthesis protein 2751041 2862515 SAS2550 Staphylococcus aureus subsp. aureus MSSA476 capsule synthesis protein YP_044664.1 2750379 R 282459 CDS YP_044665.1 49487444 2863886 complement(2751890..2752450) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2746; ica operon transcriptional regulator 2752450 2863886 SAS2551 Staphylococcus aureus subsp. aureus MSSA476 ica operon transcriptional regulator YP_044665.1 2751890 R 282459 CDS YP_044666.1 49487445 2863887 2752614..2753852 1 NC_002953.3 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 2753852 2863887 SAS2552 Staphylococcus aureus subsp. aureus MSSA476 N-glycosyltransferase YP_044666.1 2752614 D 282459 CDS YP_044667.1 49487446 2862400 2753816..2754121 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2748; intercellular adhesion protein D 2754121 2862400 SAS2553 Staphylococcus aureus subsp. aureus MSSA476 intercellular adhesion protein D YP_044667.1 2753816 D 282459 CDS YP_044668.1 49487447 2862401 2754118..2754990 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2749; intercellular adhesion protein B 2754990 2862401 SAS2554 Staphylococcus aureus subsp. aureus MSSA476 intercellular adhesion protein B YP_044668.1 2754118 D 282459 CDS YP_044669.1 49487448 2861884 2754977..2756029 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2750; intercellular adhesion protein C 2756029 2861884 SAS2555 Staphylococcus aureus subsp. aureus MSSA476 intercellular adhesion protein C YP_044669.1 2754977 D 282459 CDS YP_044670.1 49487449 2861885 complement(2756475..2758520) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2753; lipase precursor 2758520 2861885 SAS2556 Staphylococcus aureus subsp. aureus MSSA476 lipase precursor YP_044670.1 2756475 R 282459 CDS YP_044671.1 49487450 2863921 complement(2759610..2760242) 1 NC_002953.3 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP 2760242 2863921 SAS2557 Staphylococcus aureus subsp. aureus MSSA476 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP YP_044671.1 2759610 R 282459 CDS YP_044672.1 49487451 2863922 complement(2760239..2760997) 1 NC_002953.3 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2760997 2863922 SAS2558 Staphylococcus aureus subsp. aureus MSSA476 imidazole glycerol phosphate synthase subunit HisF YP_044672.1 2760239 R 282459 CDS YP_044673.1 49487452 2862275 complement(2760994..2761698) 1 NC_002953.3 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-hosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2761698 2862275 SAS2559 Staphylococcus aureus subsp. aureus MSSA476 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_044673.1 2760994 R 282459 CDS YP_044674.1 49487453 2862276 complement(2761691..2762269) 1 NC_002953.3 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2762269 hisH 2862276 hisH Staphylococcus aureus subsp. aureus MSSA476 imidazole glycerol phosphate synthase subunit HisH YP_044674.1 2761691 R 282459 CDS YP_044675.1 49487454 2862103 complement(2762266..2762844) 1 NC_002953.3 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 2762844 hisB 2862103 hisB Staphylococcus aureus subsp. aureus MSSA476 imidazoleglycerol-phosphate dehydratase YP_044675.1 2762266 R 282459 CDS YP_044676.1 49487455 2862104 complement(2762813..2763826) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2759; aminotransferase 2763826 2862104 SAS2562 Staphylococcus aureus subsp. aureus MSSA476 aminotransferase YP_044676.1 2762813 R 282459 CDS YP_044677.1 49487456 2863710 complement(2763842..2765098) 1 NC_002953.3 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2765098 2863710 SAS2563 Staphylococcus aureus subsp. aureus MSSA476 histidinol dehydrogenase YP_044677.1 2763842 R 282459 CDS YP_044678.1 49487457 2863711 complement(2765085..2765699) 1 NC_002953.3 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase 2765699 hisG 2863711 hisG Staphylococcus aureus subsp. aureus MSSA476 ATP phosphoribosyltransferase YP_044678.1 2765085 R 282459 CDS YP_044679.1 49487458 2862481 complement(2765717..2766535) 1 NC_002953.3 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase 2766535 hisZ 2862481 hisZ Staphylococcus aureus subsp. aureus MSSA476 ATP phosphoribosyltransferase YP_044679.1 2765717 R 282459 CDS YP_044680.1 49487459 2862482 complement(2766839..2767963) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2763; hypothetical protein 2767963 2862482 SAS2566 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044680.1 2766839 R 282459 CDS YP_044681.1 49487460 2862988 complement(2768081..2768578) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2764; hypothetical protein 2768578 2862988 SAS2567 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044681.1 2768081 R 282459 CDS YP_044682.1 49487461 2862989 complement(2768625..2769458) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2765; ABC transporter permease 2769458 2862989 SAS2568 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter permease YP_044682.1 2768625 R 282459 CDS YP_044683.1 49487462 2862415 complement(2769455..2771167) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2766; ABC transporter ATP-binding protein 2771167 2862415 SAS2569 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_044683.1 2769455 R 282459 CDS YP_044684.1 49487463 2862416 complement(2771220..2771774) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2767; hypothetical protein 2771774 2862416 SAS2570 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044684.1 2771220 R 282459 CDS YP_044685.1 49487464 2863884 complement(2771803..2772651) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2768; hypothetical protein 2772651 2863884 SAS2571 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044685.1 2771803 R 282459 CDS YP_044686.1 49487465 2863885 2773031..2773546 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2769; hypothetical protein 2773546 2863885 SAS2572 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044686.1 2773031 D 282459 CDS YP_044687.1 49487466 2863664 complement(2773657..2773821) 1 NC_002953.3 hypothetical protein 2773821 2863664 SAS2573 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044687.1 2773657 R 282459 CDS YP_044688.1 49487467 2863665 complement(2774026..2775000) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2770; hypothetical protein 2775000 2863665 SAS2574 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044688.1 2774026 R 282459 CDS YP_044689.1 49487468 2861867 2775241..2776197 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2771; hypothetical protein 2776197 2861867 SAS2575 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044689.1 2775241 D 282459 CDS YP_044690.1 49487469 2861868 2776349..2776987 1 NC_002953.3 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 2776987 2861868 SAS2576 Staphylococcus aureus subsp. aureus MSSA476 pyrrolidone-carboxylate peptidase YP_044690.1 2776349 D 282459 CDS YP_044691.1 49487470 2862472 2777091..2777555 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2773; hypothetical protein 2777555 2862472 SAS2577 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044691.1 2777091 D 282459 CDS YP_044692.1 49487471 2862473 complement(2777716..2781267) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2774; collagen adhesin precursor 2781267 2862473 SAS2578 Staphylococcus aureus subsp. aureus MSSA476 collagen adhesin precursor YP_044692.1 2777716 R 282459 CDS YP_044693.1 49487472 2862646 2781645..2783063 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2775; sodium:sulfate symporter family protein 2783063 2862646 SAS2579 Staphylococcus aureus subsp. aureus MSSA476 sodium:sulfate symporter family protein YP_044693.1 2781645 D 282459 CDS YP_044695.1 49487474 2863458 complement(2783476..2784384) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2776; hypothetical protein 2784384 2863458 SAS2580 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044695.1 2783476 R 282459 CDS YP_044696.1 49487475 2863459 2784606..2785181 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2777; hypothetical protein 2785181 2863459 SAS2581 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044696.1 2784606 D 282459 CDS YP_044697.1 49487476 2864396 2785347..2786363 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2778; nickel transport protein 2786363 2864396 SAS2582 Staphylococcus aureus subsp. aureus MSSA476 nickel transport protein YP_044697.1 2785347 D 282459 CDS YP_044698.1 49487477 2864397 2786600..2787400 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2779; N-acetyltransferase 2787400 2864397 SAS2583 Staphylococcus aureus subsp. aureus MSSA476 N-acetyltransferase YP_044698.1 2786600 D 282459 CDS YP_044699.1 49487478 2863743 complement(2787534..2788046) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2780; hypothetical protein 2788046 2863743 SAS2584 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044699.1 2787534 R 282459 CDS YP_044700.1 49487479 2863744 2788329..2789087 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2781; ABC transporter ATP-binding protein 2789087 2863744 SAS2585 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter ATP-binding protein YP_044700.1 2788329 D 282459 CDS YP_044701.1 49487480 2863012 2789077..2790957 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2782; ABC transporter permease 2790957 2863012 SAS2586 Staphylococcus aureus subsp. aureus MSSA476 ABC transporter permease YP_044701.1 2789077 D 282459 CDS YP_044702.1 49487481 2863013 2791050..2791241 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2783; No significant database matches. Doubtful CDS; hypothetical protein 2791241 2863013 SAS2586a Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044702.1 2791050 D 282459 CDS YP_044703.1 49487482 2862271 2791607..2791834 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2790; cold shock protein 2791834 2862271 SAS2587 Staphylococcus aureus subsp. aureus MSSA476 cold shock protein YP_044703.1 2791607 D 282459 CDS YP_044704.1 49487483 2862272 complement(2791952..2792521) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2791; hypothetical protein 2792521 2862272 SAS2588 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044704.1 2791952 R 282459 CDS YP_044705.1 49487484 2864241 complement(2792781..2793176) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2792; hypothetical protein 2793176 2864241 SAS2589 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044705.1 2792781 R 282459 CDS YP_044706.1 49487485 2864242 complement(2793244..2793597) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2793; hypothetical protein 2793597 2864242 SAS2590 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_044706.1 2793244 R 282459 CDS YP_044707.1 49487486 2862872 complement(2793914..2794753) 1 NC_002953.3 Ortholog of S. aureus MRSA252 (BX571856) SAR2795; DNA-binding protein 2794753 2862872 SAS2591 Staphylococcus aureus subsp. aureus MSSA476 DNA-binding protein YP_044707.1 2793914 R 282459 CDS YP_044708.1 49487487 2861946 complement(2794796..2795515) 1 NC_002953.3 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 2795515 gidB 2861946 gidB Staphylococcus aureus subsp. aureus MSSA476 16S rRNA methyltransferase GidB YP_044708.1 2794796 R 282459 CDS YP_044709.1 49487488 2862435 complement(2795515..2797392) 1 NC_002953.3 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 2797392 2862435 SAS2593 Staphylococcus aureus subsp. aureus MSSA476 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_044709.1 2795515 R 282459 CDS YP_044710.1 49487489 2862436 complement(2797459..2798838) 1 NC_002953.3 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 2798838 trmE 2862436 trmE Staphylococcus aureus subsp. aureus MSSA476 tRNA modification GTPase TrmE YP_044710.1 2797459 R 282459 CDS YP_044711.1 49487490 2861807 complement(2798977..2799324) 1 NC_002953.3 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 2799324 rnpA 2861807 rnpA Staphylococcus aureus subsp. aureus MSSA476 ribonuclease P YP_044711.1 2798977 R 282459 CDS YP_044712.1 49487491 2861808 complement(2799451..2799588) 1 NC_002953.3 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 2799588 rpmH 2861808 rpmH Staphylococcus aureus subsp. aureus MSSA476 50S ribosomal protein L34 YP_044712.1 2799451 R 282459 CDS YP_031698.1 49398099 2853411 12..638 1 NC_005951.1 Similar to Lactococcus lactis hypothetical ATP binding protein TR:Q9L650 (EMBL:AF242367) (207 aa) fasta scores: E(): 9.5e-26, 49.75% id in 207 aa, and to Streptococcus pneumoniae hypothetical protein TR:Q9ZHB1 (EMBL:AF068902) (213 aa) fasta scores: E(): 3.2e-24, 45.23% id in 210 aa; putative ABC transporter ATP binding protein 638 2853411 pSAS01 Staphylococcus aureus subsp. aureus MSSA476 putative ABC transporter ATP binding protein YP_031698.1 12 D 282459 CDS YP_031699.1 49398100 2853414 complement(2179..2487) 1 NC_005951.1 hypothetical protein 2487 2853414 pSAS03 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_031699.1 2179 R 282459 CDS YP_031700.1 49398101 2853422 2527..3387 1 NC_005951.1 Similar to Neisseria gonorrhoeae replication protein SW:REPA_NEIGO (P17492) (328 aa) fasta scores: E(): 6.7e-08, 22.09% id in 258 aa. Identical to Staphylococcus aureus plasmid pN315 replication protein Rep TR:Q9AC64 (EMBL:AP003139) (286 aa) fasta scores: E(): 6.4e-100, 100% id in 286 aa; replication protein 3387 2853422 pSAS04 Staphylococcus aureus subsp. aureus MSSA476 replication protein YP_031700.1 2527 D 282459 CDS YP_031701.1 49398102 2853420 3474..3815 1 NC_005951.1 Similar to Lactococcus lactis transcriptional regulator LL0007 TR:Q9CJI6 (EMBL:AE006240) (107 aa) fasta scores: E(): 5e-09, 36.6% id in 112 aa. N-terminal region is highly similar to Staphylococcus aureus plasmid pN315 hypothetical protein SAP028 TR:Q9AC63 (EMBL:AP003139) (79 aa) fasta scores: E(): 1.4e-25, 98.73% id in 79 aa; putative regulatory protein 3815 2853420 pSAS05 Staphylococcus aureus subsp. aureus MSSA476 putative regulatory protein YP_031701.1 3474 D 282459 CDS YP_031702.1 49398103 2853413 3834..4073 1 NC_005951.1 hypothetical protein 4073 2853413 pSAS06 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_031702.1 3834 D 282459 CDS YP_031703.1 49398104 2853416 4274..4459 1 NC_005951.1 Poor database matches. Similar to Staphylococcus aureus plasmid pN315 hypothetical protein SAP029 TR:Q9AC61 (EMBL:AP003139) (61 aa) fasta scores: E(): 1.1e-25, 98.36% id in 61 aa; hypothetical protein 4459 2853416 pSAS07 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_031703.1 4274 D 282459 CDS YP_031704.1 49398105 2853412 complement(4678..5421) 1 NC_005951.1 Similar to Staphylococcus aureus plasmid pSK1 replication-associated protein Orf245 TR:Q9L8I7 (EMBL:AF203376) (245 aa) fasta scores: E(): 4e-18, 45.59% id in 261 aa, and to Staphylococcus haemolyticus plasmid pNVH97A hypothetical protein TR:Q9K4M8 (EMBL:AJ400722) (245 aa) fasta scores: E(): 1.5e-40, 63.56% id in 247 aa; replication-associated protein 5421 2853412 pSAS08 Staphylococcus aureus subsp. aureus MSSA476 replication-associated protein YP_031704.1 4678 R 282459 CDS YP_031705.1 49398106 2853406 7998..8627 1 NC_005951.1 Almost identical to Staphylococcus aureus plasmid pRW001 putative cadmium resistance protein CadD TR:O05469 (EMBL:AF134905) (209 aa) fasta scores: E(): 2.9e-70, 99.04% id in 209 aa. Similar to Neisseria meningitidis cadmium resistance protein NMB1955 TR:Q9JXN6 (EMBL:AE002544) (208 aa) fasta scores: E(): 3.9e-41, 56.93% id in 209 aa; cadmium resistance transporter 8627 cadD 2853406 cadD Staphylococcus aureus subsp. aureus MSSA476 cadmium resistance transporter YP_031705.1 7998 D 282459 CDS YP_031706.1 49398107 2853410 8646..8993 1 NC_005951.1 Similar to Staphylococcus aureus plasmid pI258 cadmium efflux system accessory protein CadC SW:CADC_STAAU (P20047) (122 aa) fasta scores: E(): 7.8e-13, 42.45% id in 106 aa, and to Staphylococcus aureus plasmids pN315 and pC55s, putative regulator of cadB, CadX TR:Q9AC84 (EMBL:AP003139) (115 aa) fasta scores: E(): 1.1e-41, 99.13% id in 115 aa; putative cadmium efflux system regulatory protein 8993 cadC 2853410 cadC Staphylococcus aureus subsp. aureus MSSA476 putative cadmium efflux system regulatory protein YP_031706.1 8646 D 282459 CDS YP_031707.1 49398108 2853423 9466..10440 1 NC_005951.1 hypothetical protein 10440 2853423 pSAS13 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_031707.1 9466 D 282459 CDS YP_031708.1 49398109 2853424 complement(10560..11375) 1 NC_005951.1 Similar to Staphylococcus aureus Tn552 transposable element potential ATP-binding protein SW:ATBP_STAAU (P18179) (271 aa) fasta scores: E(): 7.4e-99, 95.94% id in 271 aa, and to Listeria innocua plasmid pLI100 hypothetical protein Pli0057 TR:Q926K3 (EMBL:AL592102) (285 aa) fasta scores: E(): 2.8e-33, 51.97% id in 279 aa; potential ATP-binding protein 11375 2853424 pSAS14 Staphylococcus aureus subsp. aureus MSSA476 potential ATP-binding protein YP_031708.1 10560 R 282459 CDS YP_031709.1 49398110 2853421 complement(12783..13376) 1 NC_005951.1 Similar to Staphylococcus aureus transposon Tn552 resolvase TnpR SW:BINL_STAAU (P18358) (197 aa) fasta scores: E(): 9.2e-71, 95.93% id in 197 aa, and to Staphylococcus epidermidis resolvase/integrase BinR TR:Q93SQ9 (EMBL:AY028779) (192 aa) fasta scores: E(): 6.9e-66, 90.62% id in 192 aa; transposon resolvase 13376 tnpR 2853421 tnpR Staphylococcus aureus subsp. aureus MSSA476 transposon resolvase YP_031709.1 12783 R 282459 CDS YP_031710.1 49398111 2853407 complement(13640..14020) 1 NC_005951.1 Highly similar to Staphylococcus aureus plasmid pI258 penicillinase repressor BlaI SW:BLAI_STAAU (P18415) (126 aa) fasta scores: E(): 3.4e-39, 99.2% id in 126 aa. Identical to Staphylococcus haemolyticus plasmids pNVH97A and pNVH96 beta-lactamase repressor BlaI TR:Q9K4N1 (EMBL:AJ400722) (126 aa) fasta scores: E(): 1e-39, 100% id in 126 aa; penicillinase repressor 14020 blaI 2853407 blaI Staphylococcus aureus subsp. aureus MSSA476 penicillinase repressor YP_031710.1 13640 R 282459 CDS YP_031711.1 49398112 2853425 complement(14010..15767) 1 NC_005951.1 Similar to Staphylococcus aureus Tn552 transposable element regulatory protein BlaR1 SW:BLAR_STAAU (P18357) (585 aa) fasta scores: E(): 7.1e-205, 94.01% id in 585 aa, and to Staphylococcus haemolyticus plasmid pNVH96 beta-lactamase inducer protein BlaR1 TR:Q9F2I0 (EMBL:AJ302698) (585 aa) fasta scores: E(): 7.9e-203, 92.99% id in 585 aa; putative beta-lactamase regulatory protein 15767 blaR1 2853425 blaR1 Staphylococcus aureus subsp. aureus MSSA476 putative beta-lactamase regulatory protein YP_031711.1 14010 R 282459 CDS YP_031712.1 49398113 2853409 15874..16719 1 NC_005951.1 Similar to Staphylococcus aureus beta-lactamase precursor BlaZ SW:BLAC_STAAU (P00807) (281 aa) fasta scores: E(): 8.6e-94, 97.5% id in 281 aa, and to Enterococcus faecalis beta-lactamase BlaZ TR:AAA24777 (EMBL:M60253) (281 aa) fasta scores: E(): 8.6e-94, 97.5% id in 281 aa; beta-lactamase precursor 16719 blaZ 2853409 blaZ Staphylococcus aureus subsp. aureus MSSA476 beta-lactamase precursor YP_031712.1 15874 D 282459 CDS YP_031713.1 49398114 2853418 17861..18010 1 NC_005951.1 No significant database matches. Similar to Borrelia burgdorferi conserved hypothetical protein BBT02 TR:Q9S019 (EMBL:AE001583) (117 aa) fasta scores: E(): 1.7, 40.9% id in 44 aa; hypothetical protein 18010 2853418 pSAS21 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_031713.1 17861 D 282459 CDS YP_031714.1 49398115 2853405 18035..18328 1 NC_005951.1 Similar to Lactococcus lactis lactococcin 972 precursor LclA TR:O86283 (EMBL:AJ002203) (91 aa) fasta scores: E(): 0.021, 30.76% id in 78 aa. Identical to Staphylococcus aureus hypothetical protein SAP019 TR:Q9AC72 (EMBL:AP003139) (97 aa) fasta scores: E(): 4.5e-39, 100% id in 97 aa; putative bacteriocin precursor 18328 2853405 pSAS22 Staphylococcus aureus subsp. aureus MSSA476 putative bacteriocin precursor YP_031714.1 18035 D 282459 CDS YP_031715.1 49398116 2853426 18403..20337 1 NC_005951.1 Similar to Lactococcus lactis hypothetical lactococcin 972 immunity protein LclB TR:Q9L651 (EMBL:AF242367) (648 aa) fasta scores: E(): 1.7e-13, 21.9% id in 662 aa. Almost identical to Staphylococcus aureus hypothetical protein SAP020 TR:Q9AC71 (EMBL:AP003139) (644 aa) fasta scores: E(): 0, 99.53% id in 644 aa; bacteriocin immunity protein 20337 2853426 pSAS23 Staphylococcus aureus subsp. aureus MSSA476 bacteriocin immunity protein YP_031715.1 18403 D 282459 CDS YP_031716.1 49398117 2853427 20341..20646 1 NC_005951.1 Similar to Bacillus subtilis hypothetical protein yxea precursor YxeA or bsu39620 SWALL:YXEA_BACSU (SWALL:P54940) (115 aa) fasta scores: E(): 0.012, 30.69% id in 101 aa; hypothetical protein 20646 2853427 pSAS24 Staphylococcus aureus subsp. aureus MSSA476 hypothetical protein YP_031716.1 20341 D 282459 CDS