-- dump date 20140620_074328 -- class Genbank::CDS -- table cds_note -- id note YP_042134.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_042135.1 binds the polymerase to DNA and acts as a sliding clamp YP_042136.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0003 YP_042137.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_042138.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0005 YP_042139.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0006 YP_042140.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0007 YP_042141.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_042142.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_042143.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0010 YP_042144.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0011 YP_042145.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0012 YP_042146.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0013 YP_042147.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0014 YP_042148.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_042149.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0016 YP_042150.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_042151.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0018 YP_042152.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0019 YP_042153.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0020 YP_042154.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0021 YP_042155.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0022 YP_042156.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0023 YP_042157.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_042158.1 N-terminus is similar to the N_terminal region of Escherichia coli type I restriction enzyme EcoR124II R protein HsdR or Hsr SWALL:T1R1_ECOLI (SWALL:P10486) (1033 aa) fasta scores: E(): 2.1e-05, 22.57% id in 762 aa. Full length CDS is similar to Caulobacter crescentus hypothetical protein CC0623 SWALL:Q9AAH5 (EMBL:AE005738) (964 aa) fasta scores: E(): 2.5e-103, 37.74% id in 959 aa YP_042159.1 Similar to Escherichia coli type I restriction enzyme EcoBI specificity protein HsdS or Hss SWALL:T1SB_ECOLI (SWALL:P06990) (474 aa) fasta scores: E(): 3.7e-10, 21.44% id in 443 aa, and to Caulobacter crescentus type I restriction-modification system, S subunit CC0621 SWALL:Q9AAH7 (EMBL:AE005738) (450 aa) fasta scores: E(): 9.9e-18, 23.18% id in 440 aa YP_042160.1 Similar to Escherichia coli type I restriction enzyme EcoR124II M protein HsdM or Hsm SWALL:T1M1_ECOLI (SWALL:P10484) (520 aa) fasta scores: E(): 8.6e-16, 23.81% id in 504 aa, and to Caulobacter crescentus type I restriction-modification system, M subunit, CC0620 SWALL:Q9AAH8 (EMBL:AE005738) (611 aa) fasta scores: E(): 2.1e-72, 42.97% id in 605 aa YP_042161.1 Similar to Staphylococcus aureus hypothetical 9.2 kDa protein SWALL:Q93IA3 (EMBL:AB037671) (80 aa) fasta scores: E(): 1.1e-24, 89.04% id in 73 aa, and to Staphylococcus aureus hypothetical 8.0 kDa protein SWALL:Q93ID7 (EMBL:AB037671) (68 aa) fasta scores: E(): 0.0037, 33.33% id in 54 aa YP_042162.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0056; Similar to Staphylococcus aureus hypothetical protein SA0054 SWALL:Q99XD7 (EMBL:AP003358) (172 aa) fasta scores: E(): 2.6e-59, 94.61% id in 167 aa YP_042163.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0057; Similar to Staphylococcus hominis hypothetical protein Orf11 SWALL:Q8VUW8 (EMBL:AB063171) (103 aa) fasta scores: E(): 1.7e-36, 93.2% id in 103 aa YP_042164.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0058; Similar to Staphylococcus aureus hypothetical 13.8 kDa protein SWALL:Q9LBZ1 (EMBL:AB033763) (116 aa) fasta scores: E(): 3.7e-44, 96.42% id in 112 aa YP_042165.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0059; Similar to Staphylococcus hominis site-specific recombinase CcrB1 SWALL:BAB83487 (EMBL:AB063171) (542 aa) fasta scores: E(): 2.8e-179, 95.01% id in 542 aa, and to Staphylococcus aureus cassette chromosome recombinase B CcrB or CcrB3 SWALL:Q9R3U2 (EMBL:AB014437) (542 aa) fasta scores: E(): 4.3e-163, 85.79% id in 542 aa YP_042166.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0060; Similar to Staphylococcus hominis site-specific recombinase CcrA1 SWALL:Q8VUX1 (EMBL:AB063171) (449 aa) fasta scores: E(): 1e-161, 94.87% id in 449 aa, and to Staphylococcus aureus cassette chromosome recombinase A1 CcrA1 SWALL:Q9S0L6 (EMBL:AB033763) (449 aa) fasta scores: E(): 3.6e-161, 94.65% id in 449 aa YP_042167.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0061; Similar to Staphylococcus hominis DNA, cassette chromosome SCC, strain:ATCC27844 hypothetical protein SWALL:Q8VUX3 (EMBL:AB063171) (589 aa) fasta scores: E(): 2.5e-202, 89.47% id in 589 aa, and to Staphylococcus aureus hypothetical protein SWALL:Q9S0L7 (EMBL:AB033763) (589 aa) fasta scores: E(): 1e-201, 88.79% id in 589 aa YP_042168.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0062; Similar to Staphylococcus aureus hypothetical 11.1 kDa protein SWALL:Q9LBZ5 (EMBL:AB033763) (98 aa) fasta scores: E(): 1e-34, 88.77% id in 98 aa, and to Staphylococcus hominis DNA, cassette chromosome scc, strain:ATCC27844 hypothetical protein SWALL:Q8VUX4 (EMBL:AB063171) (98 aa) fasta scores: E(): 7.5e-33, 84.69% id in 98 aa YP_042169.1 Poor database matches. N-terminus is similar to the N-terminal region of Ureaplasma parvum hypothetical membrane lipoprotein UU125 SWALL:Q9PR19 (EMBL:AE002113) (394 aa) fasta scores: E(): 0.0071, 23.33% id in 330 aa YP_042171.1 Poor database matches C-terminal region is similar to Brucella melitensis hypothetical protein BMEI1674 SWALL:Q8YF53 (EMBL:AE009602) (250 aa) fasta scores: E(): 1e-10, 32.61% id in 233 aa. CDS contains a coiled-coil region, residues 62 to 85 YP_042172.1 No significant database matches. Doubtful CDS YP_042173.1 Similar to Staphylococcus aureus fusidic acid resistance protein Far1 SWALL:Q8GNY5 (EMBL:AF468686) (213 aa) fasta scores: E(): 7.8e-28, 43.68% id in 206 aa YP_042174.1 Similar to Xylella fastidiosa hypothetical protein XF0543 SWALL:Q9PFW4 (EMBL:AE003901) (222 aa) fasta scores: E(): 0.0072, 26.94% id in 219 aa. N-terminal region is similar to Streptococcus pneumoniae hypothetical protein SP1047 SWALL:Q97QZ5 (EMBL:AE007407) (105 aa) fasta scores: E(): 9.9e-07, 38.09% id in 105 aa YP_042175.1 Similar to Escherichia coli phnB protein PhnB SWALL:PHNB_ECOLI (SWALL:P16681) (147 aa) fasta scores: E(): 0.046, 22.55% id in 133 aa, and to Clostridium acetobutylicum uncharacterized conserved protein, phnb family CAC3689 SWALL:Q97D00 (EMBL:AE007864) (137 aa) fasta scores: E(): 3.3e-06, 31.49% id in 127 aa YP_042176.1 Similar to Bacillus halodurans hypothetical protein BH1889 SWALL:Q9KBN6 (EMBL:AP001513) (325 aa) fasta scores: E(): 5.2e-16, 25.71% id in 315 aa, and to Listeria monocytogenes hypothetical protein LMO0364 SWALL:Q8YA03 (EMBL:AL591975) (314 aa) fasta scores: E(): 1.7e-15, 24.44% id in 315 aa YP_042177.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0025; Similar to Staphylococcus aureus region mecA element hypothetical protein Orf1260 SWALL:Q9KJC5 (EMBL:AF181950) (419 aa) fasta scores: E(): 2.2e-138, 93.51% id in 416 aa. Weakly similar to Listeria monocytogenes hypothetical protein LMO0304 SWALL:Q8YA57 (EMBL:AL591974) (421 aa) fasta scores: E(): 2.1e-18, 27.65% id in 434 aa YP_042178.1 Identical to Staphylococcus aureus enterotoxin H Seh SWALL:Q53585 (EMBL:U11702) (241 aa) fasta scores: E(): 1.2e-84, 100% id in 241 aa. Similar to Staphylococcus aureus enterotoxin type E precursor EntE SWALL:ETXE_STAAU (SWALL:P12993) (257 aa) fasta scores: E(): 2.1e-21, 37.05% id in 251 aa YP_042179.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0098 YP_042180.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0048 YP_042181.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0047 YP_042182.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0046 YP_042183.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0044 YP_042184.1 Similar to the C-terminal region of Schizosaccharomyces pombe sulfide:quinone oxidoreductase, mitochondrial precursor HMT2 or CAD1 or SPBC2G5.06c SWALL:HMT2_SCHPO (SWALL:O94284) (459 aa) fasta scores: E(): 9.1e-52, 39.36% id in 409 aa, and to the full length Bacillus cereus sulfide-quinone reductase bc3512 SWALL:Q81AP8 (EMBL:AE017009) (399 aa) fasta scores: E(): 3.3e-87, 54.7% id in 393 aa YP_042185.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0099 YP_042186.1 Similar to the C-terminal region of Bacillus anthracis hypothetical protein ba2438 SWALL:Q81QI7 (EMBL:AE017031) (81 aa) fasta scores: E(): 2.2, 33.87% id in 62 aa. Weakly similar to Escherichia coli microcin M imunity protein McmI SWALL:Q83TS3 (EMBL:AJ515251) (73 aa) fasta scores: E(): 7.7, 27.77% id in 54 aa YP_042187.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0101 YP_042188.1 Similar to Lactobacillus plantarum transport protein lp_0492 SWALL:Q88Z68 (EMBL:AL935253) (403 aa) fasta scores: E(): 1.4e-51, 38.02% id in 405 aa, and to Bacillus anthracis permease, ba2277 SWALL:Q81QY7 (EMBL:AE017031) (409 aa) fasta scores: E(): 1.2e-17, 20.84% id in 403 aa YP_042189.1 Similar to Bacillus subtilis hypothetical protein YwqN SWALL:P96726 (EMBL:Z92952) (181 aa) fasta scores: E(): 1.8e-24, 39.22% id in 181 aa, and to Bacillus cereus trp repressor binding protein bc5177 SWALL:Q815H5 (EMBL:AE017014) (181 aa) fasta scores: E(): 1.4e-23, 40.11% id in 177 aa YP_042190.1 Similar to Bacillus anthracis transcriptional regulator, LysR family ba3543 SWALL:Q81YK0 (EMBL:AE017035) (297 aa) fasta scores: E(): 8.1e-19, 29.31% id in 290 aa. C-terminus is similar to the C-terminal region of Bacillus subtilis transcriptional regulatory protein GltR or bsu26670 SWALL:GLTR_BACSU (SWALL:P94501) (296 aa) fasta scores: E(): 3.2e-13, 27.98% id in 243 aa YP_042191.1 Similar to Bacillus anthracis hypothetical protein BA1938 SWALL:Q81RU9 (EMBL:AE017030) (182 aa) fasta scores: E(): 1.8e-27, 45.05% id in 182 aa YP_042192.1 Similar to Bacillus anthracis transcriptional regulator, LysR family ba1937 SWALL:Q81RV0 (EMBL:AE017030) (262 aa) fasta scores: E(): 2.5e-11, 28.9% id in 256 aa. C-terminus is similar to the C-terminal region of Bacillus subtilis transcriptional regulatory protein GltR or bsu26670 SWALL:GLTR_BACSU (SWALL:P94501) (296 aa) fasta scores: E(): 5.7e-06, 26.05% id in 238 aa YP_042193.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0102 YP_042194.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0103 YP_042195.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0104 YP_042196.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0106 YP_042199.1 Weakly similar to Listeria monocytogenes hypothetical protein lmo2804 SWALL:Q8Y3N1 (EMBL:AL591984) (427 aa) fasta scores: E(): 3.9e-10, 25.56% id in 442 aa, and Listeria innocua hypothetical protein lin2936 SWALL:Q926V4 (EMBL:AL596174) (427 aa) fasta scores: E(): 1.4e-08, 24.44% id in 454 aa YP_042200.1 Poor database matches. Weakly similar to Streptococcus agalactiae hypothetical protein gbs1827 SWALL:Q8E3D2 (EMBL:AL766853) (130 aa) fasta scores: E(): 5.7, 25.77% id in 97 aa YP_042202.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0107 YP_042203.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0108 YP_042204.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0109 YP_042205.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0110 YP_042206.1 in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever YP_042207.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0112 YP_042208.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0113 YP_042209.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0114 YP_042210.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0115 YP_042211.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0116 YP_042212.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0117 YP_042213.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0118 YP_042214.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0119 YP_042215.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0120 YP_042216.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0121 YP_042217.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0122 YP_042218.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0123 YP_042219.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0124 YP_042220.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0125 YP_042221.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0126 YP_042222.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0127 YP_042223.1 Poor database matches. Weakly similar to Clostridium acetobutylicum uncharacterized membrane protein cac0546 SWALL:Q97LL2 (EMBL:AE007570) (116 aa) fasta scores: E(): 1.4, 25% id in 100 aa YP_042224.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0128 YP_042225.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0129 YP_042226.1 Doubtful CDS. No significant database hits YP_042227.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0130 YP_042228.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0131 YP_042229.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0132 YP_042230.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0133 YP_042231.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0134 YP_042232.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0135 YP_042233.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0136 YP_042234.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0137 YP_042235.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_042236.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0139 YP_042237.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_042238.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_042239.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0142 YP_042240.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0143 YP_042241.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0144 YP_042242.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0145 YP_042243.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0146 YP_042244.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0147 YP_042245.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0150 YP_042246.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0151 YP_042247.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0152 YP_042248.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0153 YP_042249.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0154 YP_042250.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0155 YP_042251.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0156 YP_042252.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0157 YP_042253.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0158 YP_042254.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0159 YP_042255.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0160 YP_042256.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0161 YP_042257.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0162 YP_042258.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0163 YP_042259.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0164 YP_042260.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0165 YP_042261.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0166 YP_042262.1 iron regulated; catalyzes the release of heme from hemoglobin allowing bacterial pathogens to use the host heme as an iron source YP_042263.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0168 YP_042264.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0169 YP_042265.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0170 YP_042266.1 Doubtful CDS. No significant database matches YP_042267.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0171 YP_042268.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0172 YP_042269.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0173 YP_042270.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0174 YP_042271.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0175 YP_042272.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0176 YP_042273.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0177 YP_042274.1 Catalyzes the reversible two-electron oxidation of formate to carbon dioxide. It allows the assimilation of carbon dioxide and provides energy for growth through oxidative phosphorylation coupled to the reduction of oxygen, nitrate, sulphate or fumarate YP_042275.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0179 YP_042276.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0180 YP_042277.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0181 YP_042278.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0182 YP_042279.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0183 YP_042280.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_042281.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_042282.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0186 YP_042283.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0187 YP_042284.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0188 YP_042285.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0189 YP_042286.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0190 YP_042287.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0191 YP_042288.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_042289.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0193 YP_042290.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0194 YP_042291.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0195 YP_042292.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0196 YP_042293.1 Weakly similar to Cortinarius talus ATPase subunit 6 ATP6 SWALL:Q8M3Z0 (EMBL:AF388804) (214 aa) fasta scores: E(): 0.31, 25.61% id in 203 aa, and to Bacillus cereus ABC transporter permease bc4219 SWALL:Q818N0 (EMBL:AE017011) (210 aa) fasta scores: E(): 7.8, 20.31% id in 192 aa YP_042294.1 Weakly similar to Oceanobacillus iheyensis hypothetical conserved protein ob2941 SWALL:Q8EMB6 (EMBL:AP004603) (287 aa) fasta scores: E(): 0.5, 22.37% id in 286 aa, and to the C-terminal region of Enterococcus faecalis hypothetical protein ef0417 SWALL:Q838M6 (EMBL:AE016948) (392 aa) fasta scores: E(): 0.0033, 24.56% id in 232 aa YP_042295.1 Similar to Enterococcus faecalis ABC transporter, ATP-binding protein ef2986 SWALL:Q82ZR2 (EMBL:AE016956) (224 aa) fasta scores: E(): 7.8e-39, 54.66% id in 225 aa, and to Bacillus halodurans ABC transporter bh3673 SWALL:Q9K6Q5 (EMBL:AP001519) (227 aa) fasta scores: E(): 6e-38, 49.32% id in 223 aa YP_042296.1 Similar to Clostridium perfringens probable ABC transporter cpe1540 SWALL:Q8XK63 (EMBL:AP003190) (394 aa) fasta scores: E(): 1.1e-34, 34.42% id in 398 aa, and to the C-terminal region of Escherichia coli macrolide-specific ABC-type efflux carrier MacB or b0879 SWALL:MACB_ECOLI (SWALL:P75831) (648 aa) fasta scores: E(): 4.8e-24, 26.88% id in 398 aa YP_042298.1 Weakly similar to Clostridium beijerinckii CirB protein SWALL:CAD97581 (EMBL:AJ566621) (581 aa) fasta scores: E(): 1.2e-10, 24.04% id in 599 aa, and Clostridium perfringens hypothetical protein cpe0306 SWALL:Q8XNM7 (EMBL:AP003186) (532 aa) fasta scores: E(): 0.013, 20.43% id in 558 aa YP_042299.1 Similar to the C-terminal regions of Bacillus thuringiensis integral membrane protein pbt138 SWALL:Q8KIV7 (EMBL:AL731825) (177 aa) fasta scores: E(): 1.7e-06, 26.56% id in 128 aa, and to Methanococcus jannaschii hypothetical protein mj0793 SWALL:Y793_METJA (SWALL:Q58203) (178 aa) fasta scores: E(): 1.2e-05, 30.65% id in 137 aa YP_042300.1 Weakly similar to Bacillus subtilis ATP-binding transport protein nata nata or bsu02750 SWALL:NATA_BACSU (SWALL:P46903) (246 aa) fasta scores: E(): 1e-12, 29.43% id in 214 aa, and to Clostridium tetani ABC transporter ATP-binding protein ctp37 SWALL:Q899X7 (EMBL:AF528097) (213 aa) fasta scores: E(): 8.8e-16, 35.92% id in 206 aa YP_042301.1 Poor database matches. Similar to internal region of Salmonella typhimurium melibiose carrier protein stm4299 SWALL:MELB_SALTY (SWALL:P30878) (476 aa) fasta scores: E(): 8.7, 40.35% id in 57 aa YP_042302.1 Doubtful CDS. No significant database matches YP_042303.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0198 YP_042304.1 Possible alternative translational start sites. C-terminal region is similar to Bacillus subtilis dipeptide transport system permease DppB or BSU12930 SWALL:DPPB_BACSU (SWALL:P26903) (308 aa) fasta scores: E(): 8.3e-32, 32.24% id in 307 aa, and to Fusobacterium nucleatum subsp. vincentii ATCC 49256 dipeptide transport system permease FNV2131 SWALL:Q7P899 (EMBL:AABF01000003) (308 aa) fasta scores: E(): 2.2e-45, 42.67% id in 307 aa; Ortholog of S. aureus MRSA252 (BX571856) SAR0199 YP_042305.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0200 YP_042306.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0201 YP_042307.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0202 YP_042309.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_042310.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0204 YP_042311.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0205 YP_042312.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0206 YP_042313.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0207 YP_042314.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0208 YP_042315.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0209 YP_042316.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0210 YP_042317.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0211 YP_042318.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0212 YP_042319.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate YP_042320.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0214 YP_042321.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0215 YP_042322.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0216 YP_042323.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0217 YP_042324.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0218 YP_042326.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0220 YP_042327.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0221 YP_042328.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0222 YP_042329.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0223 YP_042330.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0224 YP_042331.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0225 YP_042332.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0226 YP_042333.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0227 YP_042334.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0229 YP_042335.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0230 YP_042336.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0231 YP_042337.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0232 YP_042338.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0233 YP_042339.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0234 YP_042340.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0235 YP_042341.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0236 YP_042342.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0237; No significant database hits YP_042343.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0238 YP_042344.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0240 YP_042345.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0241 YP_042346.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0242 YP_042347.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0243 YP_042348.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0244 YP_042349.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0245 YP_042350.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_042351.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0247 YP_042352.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0248 YP_042353.1 No significant database matches. Doubtful CDS YP_042354.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0250; No significant database matches. Doubtful CDS YP_042355.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0251 YP_042356.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_042357.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0253 YP_042358.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0254 YP_042359.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0255 YP_042360.1 involved in peptidoglycan cross-linking YP_042361.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0257 YP_042362.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0258 YP_042363.1 negatively regulates murein hydrolase activity YP_042364.1 in conjunction with LrgA this protein inhibits the expression or activity of extracellular murein hydrolases YP_042365.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0262 YP_042366.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0263 YP_042367.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0264 YP_042368.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0265 YP_042369.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0266 YP_042370.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_042371.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0268 YP_042372.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0269 YP_042373.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0269a; No significant database matches. Doubtful CDS YP_042374.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0270 YP_042375.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0271 YP_042376.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0272 YP_042377.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0273 YP_042378.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0274 YP_042379.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0275 YP_042380.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0276 YP_042381.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0277 YP_042382.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0278 YP_042383.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0279 YP_042384.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0280 YP_042385.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0281 YP_042386.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0282 YP_042387.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0283 YP_042388.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0284 YP_042390.1 Similar to Listeria monocytogenes hypothetical protein lmo0063 SWALL:Q8YAQ4 (EMBL:AL591973) (99 aa) fasta scores: E(): 0.01, 22.91% id in 96 aa, and to Listeria innocua hypothetical protein lin0056 SWALL:Q92FP7 (EMBL:AL596163) (99 aa) fasta scores: E(): 0.014, 22.91% id in 96 aa YP_042391.1 Similar to Listeria monocytogenes hypothetical protein lmo0064 SWALL:Q8YAQ3 (EMBL:AL591973) (233 aa) fasta scores: E(): 0.066, 22.89% id in 214 aa, and to Listeria innocua hypothetical protein lin0057 SWALL:Q92FP6 (EMBL:AL596163) (233 aa) fasta scores: E(): 0.39, 21.69% id in 212 aa YP_042393.1 Weakly similar to Listeria monocytogenes hypothetical protein lmo0066 SWALL:Q8YAQ1 (EMBL:AL591973) (604 aa) fasta scores: E(): 2.1e-11, 22.54% id in 630 aa YP_042394.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0293 YP_042397.1 Similar to Bacillus cereus hypothetical cytosolic protein bc3263 SWALL:Q813D5 (EMBL:AE017008) (173 aa) fasta scores: E(): 8.5e-11, 31.41% id in 156 aa, and to the C-terminal region of Bacillus subtilis hypothetical cytosolic protein YeeE SWALL:O30580 (EMBL:AF012532) (369 aa) fasta scores: E(): 1.4e-11, 28.76% id in 146 aa YP_042398.1 Similar to Bacillus halodurans hypothetical protein bh3703 SWALL:Q9K6M5 (EMBL:AP001519) (169 aa) fasta scores: E(): 2e-07, 30.06% id in 163 aa, and to the C-terminal region of Bacillus subtilis hypothetical protein YeeE SWALL:O30580 (EMBL:AF012532) (369 aa) fasta scores: E(): 5.8e-11, 30.13% id in 146 aa YP_042399.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0294; Similar to Bacillus cereus hypothetical cytosolic protein bc3263 SWALL:Q813D5 (EMBL:AE017008) (173 aa) fasta scores: E(): 2.8e-13, 36.02% id in 161 aa, and to the C-terminal region of Bacillus subtilis hypothetical protein YeeE SWALL:O30580 (EMBL:AF012532) (369 aa) fasta scores: E(): 3.5e-13, 32.85% id in 140 aa YP_042400.1 Similar to Bacillus cereus hypothetical cytosolic protein bc3263 SWALL:Q813D5 (EMBL:AE017008) (173 aa) fasta scores: E(): 4e-10, 30.51% id in 154 aa, and to the C-terminal region Bacillus subtilis hypothetical protein YeeE SWALL:O30580 (EMBL:AF012532) (369 aa) fasta scores: E(): 3.5e-09, 27.33% id in 150 aa YP_042401.1 Similar to Bacillus cereus hypothetical cytosolic protein bc3263 SWALL:Q813D5 (EMBL:AE017008) (173 aa) fasta scores: E(): 1e-10, 33.11% id in 154 aa, and to the C-terminal region of Bacillus subtilis hypothetical protein YeeE SWALL:O30580 (EMBL:AF012532) (369 aa) fasta scores: E(): 9.4e-11, 30.71% id in 140 aa YP_042402.1 Similar to Bacillus cereus hypothetical cytosolic protein bc3263 SWALL:Q813D5 (EMBL:AE017008) (173 aa) fasta scores: E(): 2.8e-14, 37.01% id in 154 aa, and to the C-terminal region of Bacillus subtilis hypothetical protein YeeE SWALL:O30580 (EMBL:AF012532) (369 aa) fasta scores: E(): 3.3e-12, 32.14% id in 140 aa YP_042403.1 Similar to Bacillus cereus hypothetical cytosolic protein bc3263 SWALL:Q813D5 (EMBL:AE017008) (173 aa) fasta scores: E(): 1.3e-10, 33.11% id in 154 aa, and to the C-terminal region of Bacillus subtilis YeeE SWALL:O30580 (EMBL:AF012532) (369 aa) fasta scores: E(): 3.1e-11, 31.42% id in 140 aa YP_042404.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0297; Similar to Bacillus cereus hypothetical cytosolic protein bc3263 SWALL:Q813D5 (EMBL:AE017008) (173 aa) fasta scores: E(): 1.8e-12, 33.33% id in 156 aa, and to the C-terminal region of Bacillus subtilis YeeE SWALL:O30580 (EMBL:AF012532) (369 aa) fasta scores: E(): 1.4e-11, 29.45% id in 146 aa YP_042405.1 Poor database matches. Weakly similar to Clostridium tetani hypothetical protein ctc00500 SWALL:Q898F5 (EMBL:AE015937) (145 aa) fasta scores: E(): 0.27, 26.98% id in 126 aa YP_042406.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0301 YP_042407.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0302 YP_042408.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0303 YP_042409.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0304 YP_042410.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0305 YP_042411.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0306 YP_042412.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0307 YP_042413.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0308 YP_042414.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0309 YP_042415.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0310 YP_042416.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0311 YP_042417.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid YP_042418.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0313 YP_042419.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0314 YP_042420.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_042421.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0316 YP_042422.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0317 YP_042423.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0318 YP_042424.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0319 YP_042425.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0320 YP_042426.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0321 YP_042427.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0322 YP_042428.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0323 YP_042429.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0324 YP_042430.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0325 YP_042431.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_042432.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0327 YP_042433.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0328 YP_042434.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0329 YP_042435.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0330 YP_042436.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0331 YP_042437.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0332 YP_042438.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0333 YP_042439.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0334 YP_042440.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0335 YP_042441.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0336 YP_042442.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0338 YP_042443.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0339 YP_042444.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0340 YP_042445.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0341 YP_042446.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0342 YP_042447.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0343 YP_042448.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0344 YP_042449.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0345 YP_042450.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0346 YP_042451.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0347 YP_042452.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0348 YP_042453.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0349 YP_042454.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0350 YP_042455.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0351 YP_042456.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0352 YP_042457.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_042458.1 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions YP_042459.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0355 YP_042460.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0356 YP_042461.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0357 YP_042462.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0358 YP_042463.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0359 YP_042464.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_042465.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0361 YP_042466.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_042467.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0363 YP_042468.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_042469.1 N-terminal region is similar to Bacillus anthracis hypothetical protein bxa0052 SWALL:Q9X309 (EMBL:AF065404) (276 aa) fasta scores: E(): 1.7e-11, 38.26% id in 230 aa, and to the N-terminal region of Enterococcus faecalis hypothetical protein ef2085 SWALL:Q832Y3 (EMBL:AE016953) (322 aa) fasta scores: E(): 0.0034, 26.37% id in 273 aa YP_042470.1 Poor database matches. C-terminus is similar to the C-terminal region of Staphylococcus aureus exotoxin 1 Set1 SWALL:Q9RN32 (EMBL:AF188837) (231 aa) fasta scores: E(): 0.034, 30.92% id in 152 aa YP_042471.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0389 YP_042472.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0390 YP_042473.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0391 YP_042474.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0392 YP_042475.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0393 YP_042476.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0394 YP_042477.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0395 YP_042478.1 Ortholog of S. aureus MRSA252 (BX571856) SAR395a; No significant database matches. Doubtful CDS YP_042479.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0396 YP_042480.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0397 YP_042481.1 EC_number 1.6.4.-; Ortholog of S. aureus MRSA252 (BX571856) SAR0398 YP_042482.1 EC_number 1.6.4.-; Ortholog of S. aureus MRSA252 (BX571856) SAR0399 YP_042483.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0400 YP_042484.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0401 YP_042485.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0401a; No significant database matches. Doubtful CDS YP_042486.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0403 YP_042487.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0404 YP_042488.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0405 YP_042489.1 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine YP_042490.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0407 YP_042491.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0408 YP_042492.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_042494.1 Poor database matches. Weakly similar to the C-terminal region of Buchnera aphidicola high-affinity zinc uptake system membrane protein bbp294 SWALL:Q89AJ1 (EMBL:AE014017) (261 aa) fasta scores: E(): 4.7, 35.41% id in 48 aa YP_042498.1 Poor database matches. C-terminus is similar to the C-terminal region of Streptococcus mutans hypothetical protein SMU.423 SWALL:Q8DVP7 (EMBL:AE014889) (76 aa) fasta scores: E(): 0.062, 47.54% id in 61 aa YP_042499.1 Poor database matches. Similar to Campylobacter jejuni rloF protein SWALL:Q8G8B7 (EMBL:AF542644) (554 aa) fasta scores: E(): 0.054, 25.08% id in 606 aa YP_042500.1 Weakly similar to Clostridium perfringens hypothetical protein cpe1491 SWALL:Q8XKA9 (EMBL:AP003190) (140 aa) fasta scores: E(): 1.7, 24.82% id in 141 aa YP_042502.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0418 YP_042503.1 Similar to Clostridium tetani conserved protein ctc00602 SWALL:Q897W9 (EMBL:AE015938) (138 aa) fasta scores: E(): 9.2e-11, 41.3% id in 138 aa, and to Bacillus anthracis hypothetical protein ba4379 SWALL:Q81M73 (EMBL:AE017037) (135 aa) fasta scores: E(): 8e-10, 38.97% id in 136 aa YP_042504.1 Similar to Enterococcus faecalis hypothetical protein ef1702 SWALL:Q834F3 (EMBL:AE016952) (154 aa) fasta scores: E(): 1.9e-27, 58.5% id in 147 aa, and to Bacillus subtilis hypothetical protein YbbK or bsu01720 SWALL:YBBK_BACSU (SWALL:Q45584) (151 aa) fasta scores: E(): 9.4e-25, 53.02% id in 149 aa YP_042505.1 Similar to Neisseria meningitidis hypothetical protein nma2192 or rei1 SWALL:Q9JQX9 (EMBL:AL162758) (219 aa) fasta scores: E(): 1.1e-26, 43.83% id in 219 aa, and to the C-terminal region of Corynebacterium efficiens conserved hypothetical protein ce0348 SWALL:Q8FSN5 (EMBL:AP005215) (281 aa) fasta scores: E(): 7.7e-37, 48.9% id in 229 aa YP_042506.1 Doubtful CDS. No significant database hits YP_042507.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0420 YP_042508.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0421 YP_042509.1 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation YP_042510.1 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation YP_042511.1 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation YP_042512.1 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation YP_042513.1 SSL5, SET3, SET10; bind P-selectin glycoprotein ligand-1 and inhibit P-selectin-mediated neutrophil rolling along the endothelium; these proteins share structural homology to known superantigens but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation YP_042514.1 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation YP_042515.1 SSL7, SET1; blocks IgA-FcR interactions and inhibits complement, leading to increased survival of a sensitive bacterium in blood YP_042516.2 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation YP_042517.1 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation YP_042518.1 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation YP_042519.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0432; Doubtful CDS. No significant database hits YP_042521.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0434 YP_042522.1 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation YP_042523.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0436 YP_042524.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0437 YP_042525.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0440 YP_042526.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0442 YP_042528.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0444 YP_042529.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0443 YP_042530.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0446 YP_042531.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0447 YP_042532.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0448 YP_042533.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0449 YP_042534.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0450 YP_042535.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0451 YP_042536.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_042537.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0453 YP_042538.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0454 YP_042539.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0455 YP_042540.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0456 YP_042541.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0457 YP_042542.1 Doubtful CDS. No database matches YP_042543.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0458 YP_042544.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0459 YP_042545.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0460 YP_042546.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0461 YP_042547.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0462 YP_042548.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0463 YP_042549.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0464 YP_042550.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0465 YP_042551.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0466 YP_042552.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0467 YP_042553.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0468 YP_042554.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0469 YP_042555.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0470 YP_042556.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0471 YP_042557.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_042558.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0473 YP_042559.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0474 YP_042560.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0475 YP_042562.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0476 YP_042563.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0477 YP_042564.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0478 YP_042565.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_042566.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0482 YP_042567.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_042568.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0484 YP_042569.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0485 YP_042570.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0486 YP_042571.1 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA YP_042572.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0488 YP_042573.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0489 YP_042574.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0490 YP_042575.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_042576.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0492 YP_042577.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0493 YP_042578.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_042579.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0495 YP_042580.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_042581.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0497 YP_042582.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0498 YP_042583.1 stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus YP_042584.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_042585.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_042586.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_042587.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_042588.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0504 YP_042589.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0505 YP_042590.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0506 YP_042591.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0507 YP_042592.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0508 YP_042593.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0509 YP_042594.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0510 YP_042595.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0511 YP_042596.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0512 YP_042597.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_042598.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0514 YP_042599.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0515 YP_042600.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0516 YP_042601.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0517 YP_042602.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_042603.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0521 YP_042604.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate YP_042605.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate YP_042606.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0524 YP_042607.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0525 YP_042608.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0526 YP_042609.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0527 YP_042610.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0528 YP_042611.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_042612.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0530 YP_042613.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_042614.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0532 YP_042615.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_042616.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0534 YP_042617.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0535 YP_042618.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0536 YP_042619.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0537 YP_042620.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif YP_042621.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_042622.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0540 YP_042623.1 binds directly to 23S ribosomal RNA YP_042624.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_042625.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_042626.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_042627.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0546 YP_042628.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_042629.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_042630.1 in Bacillus subtilis this non-essential protein associates with the ribosome YP_042631.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_042632.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_042633.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_042634.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_042635.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0554 YP_042636.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_042637.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress YP_042638.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_042639.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0558 YP_042640.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_042641.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0560 YP_042642.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0561 YP_042643.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0562 YP_042644.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0563 YP_042645.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0564 YP_042646.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0565 YP_042647.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0566 YP_042649.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0567 YP_042650.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0568 YP_042651.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0569 YP_042652.1 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis YP_042653.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0571 YP_042654.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0572 YP_042655.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0573 YP_042656.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0574 YP_042657.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0575 YP_042658.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0576 YP_042659.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0577 YP_042660.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0578 YP_042661.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0580 YP_042662.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0581 YP_042663.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0582 YP_042664.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0583 YP_042665.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0584 YP_042666.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0585 YP_042667.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_042668.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0587 YP_042669.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0588 YP_042670.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0589 YP_042671.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0590 YP_042672.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0591 YP_042673.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0592 YP_042674.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0593 YP_042675.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_042676.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0595 YP_042677.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0596 YP_042678.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0597 YP_042679.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0598 YP_042680.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0599 YP_042681.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0600 YP_042682.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0601 YP_042683.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0602 YP_042684.1 Similar to Staphylococcus haemolyticus hypothetical protein SWALL:Q9F2H5 (EMBL:AJ302698) (220 aa) fasta scores: E(): 6.1e-07, 23.28% id in 189 aa, and to Oceanobacillus iheyensis hypothetical conserved protein ob3290 SWALL:Q8ELD9 (EMBL:AP004604) (212 aa) fasta scores: E(): 3.6e-06, 21.56% id in 218 aa YP_042685.1 Similar to Oceanobacillus iheyensis hypothetical conserved protein ob1330 SWALL:Q8ERH2 (EMBL:AP004597) (217 aa) fasta scores: E(): 2.9e-07, 26.6% id in 218 aa, and to Staphylococcus haemolyticus hypothetical protein SWALL:Q9F2H5 (EMBL:AJ302698) (220 aa) fasta scores: E(): 5.3e-07, 27.55% id in 196 aa YP_042686.1 Similar to Oceanobacillus iheyensis hypothetical conserved protein ob1336 SWALL:Q8ERG6 (EMBL:AP004597) (219 aa) fasta scores: E(): 2.3e-06, 25.58% id in 215 aa, and to Staphylococcus haemolyticus hypothetical protein SWALL:Q9F2H5 (EMBL:AJ302698) (220 aa) fasta scores: E(): 1.3e-05, 21.1% id in 199 aa YP_042687.1 Similar to Oceanobacillus iheyensis hypothetical conserved protein ob1320 SWALL:Q8ERI2 (EMBL:AP004597) (215 aa) fasta scores: E(): 5.8e-07, 24.17% id in 211 aa, and to Staphylococcus haemolyticus hypothetical protein SWALL:Q9F2H5 (EMBL:AJ302698) (220 aa) fasta scores: E(): 2e-07, 22.48% id in 209 aa YP_042688.1 Similar to Staphylococcus haemolyticus hypothetical protein SWALL:Q9F2H5 (EMBL:AJ302698) (220 aa) fasta scores: E(): 3.4e-07, 22.91% id in 192 aa, and to Oceanobacillus iheyensis hypothetical conserved protein ob3291 SWALL:Q8ELD8 (EMBL:AP004604) (216 aa) fasta scores: E(): 9.7e-07, 24.51% id in 208 aa YP_042689.1 Similar to Oceanobacillus iheyensis hypothetical conserved protein ob1336 SWALL:Q8ERG6 (EMBL:AP004597) (219 aa) fasta scores: E(): 8.9e-09, 24.88% id in 221 aa, and to Staphylococcus haemolyticus hypothetical protein SWALL:Q9F2H5 (EMBL:AJ302698) (220 aa) fasta scores: E(): 1.1e-07, 25.26% id in 186 aa YP_042690.1 Similar to Staphylococcus haemolyticus hypothetical protein SWALL:Q9F2H5 (EMBL:AJ302698) (220 aa) fasta scores: E(): 8.2e-10, 27.6% id in 192 aa, and to Oceanobacillus iheyensis hypothetical conserved protein ob3290 SWALL:Q8ELD9 (EMBL:AP004604) (212 aa) fasta scores: E(): 1.1e-09, 26.31% id in 209 aa YP_042691.1 Similar to Oceanobacillus iheyensis hypothetical conserved protein ob1330 SWALL:Q8ERH2 (EMBL:AP004597) (217 aa) fasta scores: E(): 1.2e-09, 29.24% id in 212 aa, and to Staphylococcus haemolyticus hypothetical protein SWALL:Q9F2H5 (EMBL:AJ302698) (220 aa) fasta scores: E(): 2.2e-07, 27.04% id in 196 aa YP_042692.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0603 YP_042693.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0605 YP_042694.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0608 YP_042695.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0609 YP_042696.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0610 YP_042697.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0611 YP_042698.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0612 YP_042699.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_042700.1 Doubtful CDS. No database matches YP_042701.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0614 YP_042702.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_042703.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0617 YP_042704.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0618 YP_042705.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0619 YP_042706.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0620 YP_042707.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0621 YP_042708.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0622 YP_042709.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0623 YP_042710.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0624 YP_042711.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0625 YP_042712.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0626 YP_042713.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0627 YP_042714.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0628 YP_042715.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0629 YP_042716.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_042717.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_042718.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_042719.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; in S. meliloti it is known to be involved specifically with K+ transport YP_042720.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport YP_042721.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_042722.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_042723.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0637 YP_042724.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0641 YP_042725.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0642 YP_042726.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0643 YP_042727.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0644 YP_042728.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0645 YP_042729.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0646 YP_042730.1 with TagG is involved in the export of teichoic acids YP_042731.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0648 YP_042732.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0649 YP_042733.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0650 YP_042734.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0651 YP_042735.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0652 YP_042736.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0653 YP_042738.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0655 YP_042739.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0656 YP_042740.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0657 YP_042741.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0658 YP_042742.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0659 YP_042743.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase YP_042744.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0661 YP_042745.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0662 YP_042746.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0663 YP_042747.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0664 YP_042748.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0665 YP_042749.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0666 YP_042750.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0667 YP_042751.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0668 YP_042752.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0669 YP_042753.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0670 YP_042754.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0671 YP_042755.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0672 YP_042756.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0673 YP_042757.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0674 YP_042758.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0675 YP_042759.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0676 YP_042760.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0677 YP_042761.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0679 YP_042762.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0680 YP_042763.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0681 YP_042764.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0682 YP_042765.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0683 YP_042766.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0684 YP_042767.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0685 YP_042768.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0728 YP_042769.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0729 YP_042770.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0730 YP_042771.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0731 YP_042772.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0732 YP_042773.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0733 YP_042774.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0734 YP_042775.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0735 YP_042776.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_042777.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0737 YP_042778.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0738 YP_042779.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0739 YP_042780.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0740 YP_042781.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0741 YP_042782.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0742 YP_042783.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0743 YP_042784.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0744 YP_042785.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0745 YP_042786.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0746 YP_042787.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0747 YP_042788.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0748 YP_042789.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0749 YP_042790.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0750 YP_042791.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0751 YP_042792.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0752 YP_042793.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0753 YP_042794.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0754 YP_042795.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0755 YP_042796.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0756 YP_042797.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0757 YP_042798.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0758 YP_042799.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0759 YP_042800.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0760 YP_042801.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0761 YP_042802.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0762 YP_042803.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0763 YP_042804.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0764 YP_042805.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0765 YP_042806.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0766 YP_042807.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0767 YP_042808.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0768 YP_042809.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0769 YP_042810.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0770 YP_042811.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0771 YP_042812.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0772 YP_042813.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0773 YP_042814.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0774 YP_042815.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0775 YP_042816.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0776 YP_042817.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_042818.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0778 YP_042819.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0780 YP_042820.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0781 YP_042821.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis YP_042822.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0783 YP_042823.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_042824.1 Catalyzes the rate-limiting step in dNTP synthesis YP_042825.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_042826.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0787 YP_042827.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0788 YP_042828.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0789 YP_042829.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0790 YP_042830.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0791 YP_042831.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_042832.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0793 YP_042833.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0794 YP_042834.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0795 YP_042835.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0796 YP_042836.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_042837.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0798 YP_042838.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0799 YP_042839.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0800 YP_042840.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0801 YP_042841.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0802 YP_042842.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0803 YP_042843.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0804 YP_042844.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0805 YP_042845.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0806 YP_042846.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_042847.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_042848.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0809 YP_042849.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0810 YP_042850.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0811 YP_042851.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_042852.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_042853.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system YP_042854.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_042855.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0816 YP_042856.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0817 YP_042857.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0818 YP_042858.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0820 YP_042859.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0821 YP_042860.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0822 YP_042861.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_042862.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0825 YP_042863.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0826 YP_042864.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0827 YP_042865.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0828 YP_042866.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_042867.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_042868.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_042869.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_042870.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0833 YP_042871.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0834 YP_042872.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0835 YP_042873.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0836 YP_042874.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_042875.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0839 YP_042876.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0840 YP_042877.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0841 YP_042878.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0842 YP_042879.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0843 YP_042880.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0845 YP_042881.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0846 YP_042882.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0847 YP_042883.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0848 YP_042884.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0849 YP_042885.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0850 YP_042886.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0851 YP_042887.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0852 YP_042888.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0853 YP_042889.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0854 YP_042890.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0855 YP_042891.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0856 YP_042892.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0857 YP_042893.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0858 YP_042895.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0859 YP_042896.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis YP_042897.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0861 YP_042898.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0862 YP_042899.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0863 YP_042900.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_042901.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0865 YP_042902.1 Doubtful CDS. No significant database matches YP_042903.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0867 YP_042904.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0868 YP_042905.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0870 YP_042906.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0871 YP_042907.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0872 YP_042908.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0874 YP_042909.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0875 YP_042910.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0876 YP_042911.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0877 YP_042912.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0878 YP_042913.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0879 YP_042914.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0880 YP_042915.1 Doubtful CDS. No database matches YP_042916.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0881 YP_042917.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0882 YP_042918.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0883 YP_042919.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0884 YP_042920.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0885 YP_042921.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0886 YP_042922.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_042923.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0888 YP_042924.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0889 YP_042925.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0890 YP_042926.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0891 YP_042927.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0892 YP_042928.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0893; No significant database matches YP_042929.1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid YP_042930.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0895 YP_042931.1 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid YP_042932.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0897 YP_042933.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0898 YP_042934.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0899 YP_042935.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0900 YP_042936.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0901 YP_042937.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0902 YP_042938.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0903 YP_042939.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0904 YP_042940.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0905 YP_042941.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0906 YP_042942.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0907 YP_042943.1 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_042944.1 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_042945.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_042946.1 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone YP_042947.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_042948.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in the case of S. meliloti it was proved to be involved specifically with K+ transport YP_042949.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_042950.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0915 YP_042951.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0916 YP_042952.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0917 YP_042953.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0918 YP_042954.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0919 YP_042955.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0920 YP_042956.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0921 YP_042957.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_042958.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_042959.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_042960.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0925 YP_042961.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0926 YP_042962.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0927 YP_042963.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0928 YP_042964.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0929 YP_042965.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0930 YP_042966.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0931 YP_042967.1 NADPH-dependent; catalyzes the reduction of coenzyme A disulfide YP_042968.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0934 YP_042969.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0935 YP_042970.1 No database matches YP_042971.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0937 YP_042972.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0938 YP_042973.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0939 YP_042974.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0940 YP_042975.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0941 YP_042976.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0942 YP_042977.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0943 YP_042978.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0944 YP_042979.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0945 YP_042980.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_042981.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0947 YP_042982.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0948 YP_042983.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0949 YP_042984.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0950 YP_042985.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0951 YP_042986.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0952 YP_042987.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0953 YP_042988.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0954 YP_042989.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0957 YP_042990.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0958 YP_042992.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0960 YP_042993.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_042994.1 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress YP_042995.1 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence YP_042996.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0967 YP_042997.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0968 YP_042998.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0969 YP_042999.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0970 YP_043000.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0971 YP_043001.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0972 YP_043002.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0973 YP_043003.1 catalyzes the phosphorylation of NAD to NADP YP_043004.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0975 YP_043005.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0976 YP_043006.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0977 YP_043007.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_043008.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0979 YP_043009.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0980 YP_043010.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0981 YP_043011.1 similar to 2'-5' RNA ligase YP_043012.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0986 YP_043013.1 processive; catalyzes the formation of mono-, di- and tri-glucosyldiacylglycerol by the progressive transfer of glucosyl residues to diacylglycerol; involved in the formation of membrane glycolipids YP_043014.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine YP_043015.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0989 YP_043016.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_043017.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0991 YP_043018.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1562 YP_043019.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1561 YP_043020.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1560 YP_043021.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1559 YP_043022.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1558 YP_043023.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1557 YP_043024.1 Similar to Bacteriophage A118 repressor protein SWALL:Q9T188 (EMBL:AJ242593) (101 aa) fasta scores: E(): 0.00012, 32.65% id in 98 aa, and to Enterococcus faecalis transcriptional regulator, Cro/CI family ef1422 SWALL:Q835F5 (EMBL:AE016951) (107 aa) fasta scores: E(): 0.00014, 33.01% id in 106 aa YP_043025.1 Similar to Lactococcus phage BK5-T Cro repressor SWALL:Q38329 (EMBL:AF176025) (79 aa) fasta scores: E(): 0.016, 33.33% id in 60 aa, and to Streptococcus pyogenes, Streptococcus pyogenes Cro-like repressor protein-phage associated spy1485 or spym18_1503 or spym3_1142 or sps0720 SWALL:Q99YY6 (EMBL:AE006582) (70 aa) fasta scores: E(): 0.034, 36.95% id in 46 aa YP_043027.1 Similar to Sulfolobus sp. NOB8H2 hypothetical protein SWALL:O93686 (EMBL:AJ010405) (72 aa) fasta scores: E(): 0.98, 37.03% id in 54 aa YP_043028.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1548 YP_043029.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1547 YP_043030.1 Similar to Staphylococcus aureus phage phi 13 phi PVL orf 38-like protein SWALL:Q8SDM7 (EMBL:AF424783) (53 aa) fasta scores: E(): 2.8e-20, 92.45% id in 53 aa, and to Staphylococcus aureus prophage phiPV83 phi PVL orf 38 homologue SWALL:Q9MBS6 (EMBL:AB044554) (55 aa) fasta scores: E(): 9e-20, 94.23% id in 52 aa YP_043031.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2088 YP_043032.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1544 YP_043033.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1543 YP_043034.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1542 YP_043035.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1541 YP_043036.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1540 YP_043037.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1539 YP_043038.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1538 YP_043039.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2076 YP_043040.1 Similar to N-terminal region of Staphylococcus aureus phage phi 12 PVL orf 52-like protein SWALL:Q8SDR1 (EMBL:AF424782) (133 aa) fasta scores: E(): 5.1e-07, 43.28% id in 67 aa YP_043041.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1535 YP_043042.1 Identical to Staphylococcus aureus phage phi 12 hypothetical phage protein SWALL:Q8SBD5 (EMBL:AF424782) (115 aa) fasta scores: E(): 4.2e-42, 100% id in 115 aa YP_043043.1 Highly similar to Staphylococcus aureus phage phi 12 PV83 orf 27-like protein SWALL:Q8SDR0 (EMBL:AF424782) (102 aa) fasta scores: E(): 1.3e-33, 97.05% id in 102 aa YP_043044.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2074 YP_043045.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1531 YP_043046.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1530 YP_043047.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2071 YP_043049.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1527 YP_043051.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1526 YP_043052.1 Poor database matches. Weakly similar to Pyrococcus horikoshii hypothetical upf0248 protein PH1212.1 SWALL:YC1A_PYRHO (SWALL:P59734) (83 aa) fasta scores: E(): 4.5, 27.53% id in 69 aa YP_043053.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1525 YP_043054.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1524 YP_043055.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1523 YP_043056.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1522 YP_043057.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1521 YP_043058.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1520 YP_043059.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1519 YP_043060.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1518 YP_043061.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1517 YP_043062.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1516 YP_043063.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1515 YP_043064.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1514 YP_043065.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1513 YP_043066.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1512 YP_043067.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1511 YP_043068.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1510 YP_043069.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1509 YP_043070.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1508 YP_043071.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1507 YP_043072.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1506 YP_043073.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1505 YP_043074.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1504 YP_043075.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1503 YP_043076.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1502 YP_043077.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1501 YP_043078.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1500 YP_043079.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1499 YP_043080.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1498 YP_043081.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1497 YP_043082.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0992 YP_043083.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0993 YP_043084.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0994 YP_043085.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0995 YP_043086.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0996 YP_043087.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0997 YP_043088.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0998 YP_043089.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0999 YP_043090.1 No significant database matches. Doubtful CDS YP_043091.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1001 YP_043092.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1003 YP_043093.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1004 YP_043094.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1005 YP_043095.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1007 YP_043096.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1008 YP_043097.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1010 YP_043098.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1011 YP_043099.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1012 YP_043100.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1013 YP_043101.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1014 YP_043102.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_043103.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1016 YP_043104.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1017 YP_043105.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1018 YP_043106.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_043107.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1020 YP_043108.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1021 YP_043109.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1022 YP_043110.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1023 YP_043111.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1024 YP_043112.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1025 YP_043113.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1026 YP_043114.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1027 YP_043115.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1028 YP_043116.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1029 YP_043117.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1030 YP_043118.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1031 YP_043119.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1032 YP_043120.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1033 YP_043121.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1034 YP_043122.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1035 YP_043123.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_043124.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1038 YP_043125.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_043126.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_043127.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1041 YP_043128.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_043129.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_043130.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_043131.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_043132.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1046 YP_043133.1 involved in de novo purine biosynthesis YP_043134.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_043135.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1049 YP_043136.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1050 YP_043137.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1051 YP_043138.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1052 YP_043139.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1053 YP_043140.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1054 YP_043141.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1055 YP_043142.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1056 YP_043143.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1057 YP_043144.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1058 YP_043145.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1059 YP_043146.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1060 YP_043147.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1061 YP_043148.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1063 YP_043149.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1064 YP_043150.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_043151.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1066 YP_043152.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1067 YP_043153.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1068 YP_043154.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1069 YP_043155.1 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_043156.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1071 YP_043157.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1072 YP_043158.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1073 YP_043159.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1074 YP_043160.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1075 YP_043161.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1076 YP_043162.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1077 YP_043163.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1078 YP_043164.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1079 YP_043165.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1080 YP_043166.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1081 YP_043167.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1082 YP_043168.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1083 YP_043169.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1084 YP_043170.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1085 YP_043171.1 depletion of this protein in Bacillus subtilis results in defects in cell morphology; crystal structure of Staphylococcus protein shows homodimer; ligand binding protein YP_043172.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1087 YP_043173.1 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate YP_043174.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1089 YP_043175.1 converts protoheme IX and farnesyl diphosphate to heme O YP_043176.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1091 YP_043177.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1092 YP_043178.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1093 YP_043179.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1094 YP_043180.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1095 YP_043181.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1096 YP_043182.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1097 YP_043183.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_043184.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1099 YP_043185.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1100 YP_043186.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_043187.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1102 YP_043188.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1103 YP_043189.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1104 YP_043190.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1105 YP_043191.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1106 YP_043192.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1107 YP_043193.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1108 YP_043194.1 iron regulated; catalyzes the release of heme from hemoglobin allowing bacterial pathogens to use the host heme as an iron source YP_043195.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1109a; Doubtful CDS. No database matches YP_043196.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1110 YP_043197.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_043198.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_043199.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_043200.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1114 YP_043201.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1115 YP_043202.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1116 YP_043203.1 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange YP_043204.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1118 YP_043205.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_043206.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1120 YP_043207.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_043208.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_043209.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_043210.1 hydrolyzes non-standard nucleotides such as xanthine and inosine YP_043211.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1125 YP_043212.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1126 YP_043213.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1127 YP_043214.1 FLIPr; secreted protein that blocks the formyl peptide receptor-like 1 (FPRL1) found in neutrophils, monocytes, B cells, and NK cells; inhibits the binding of chemoattractants (such as formylated peptides) to FPRL1, which initiates the phagocyte mobilization towards the infection site YP_043215.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1129 YP_043216.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1130 YP_043217.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1131 YP_043219.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1133 YP_043220.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1133a; Poor database matches. Weakly similar to Staphylococcus aureus an internal region of AgrB protein SWALL:Q53644 (EMBL:X52543) (423 aa) fasta scores: E(): 2.2, 30% id in 70 aa. Possible gene remnant YP_043221.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1134 YP_043222.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1136 YP_043223.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1136a; Doubtful CDS. No database matches YP_043224.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1137 YP_043225.1 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation YP_043226.1 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation YP_043227.1 these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation YP_043228.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_043229.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_043230.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1144 YP_043231.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1146 YP_043232.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1147 YP_043233.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1148 YP_043234.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1150 YP_043236.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1151 YP_043237.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1152 YP_043238.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1153 YP_043239.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_043240.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1155 YP_043241.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1156 YP_043242.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1157 YP_043243.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_043244.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_043245.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1160 YP_043246.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1161 YP_043247.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_043248.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1163 YP_043249.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1164 YP_043250.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1165 YP_043251.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1166 YP_043252.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1167 YP_043253.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1168 YP_043254.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_043255.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1171 YP_043256.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_043257.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1173 YP_043258.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_043259.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1175 YP_043260.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_043261.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_043262.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_043263.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_043264.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_043265.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_043266.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1182 YP_043267.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1183 YP_043268.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1184 YP_043269.1 Essential for recycling GMP and indirectly, cGMP YP_043270.1 Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_043271.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1187 YP_043272.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1188 YP_043273.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1189 YP_043274.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1190 YP_043275.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_043276.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1192 YP_043277.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1193 YP_043278.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_043279.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1195 YP_043280.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1196 YP_043281.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1197 YP_043282.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1198 YP_043283.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1199 YP_043284.1 required for 70S ribosome assembly YP_043285.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1201 YP_043286.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1202 YP_043287.1 catalyzes branch migration in Holliday junction intermediates YP_043288.1 negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria YP_043289.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_043290.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1206 YP_043291.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1207 YP_043292.1 carries the fatty acid chain in fatty acid biosynthesis YP_043293.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_043294.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1210 YP_043295.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1211 YP_043296.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1212 YP_043297.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1213 YP_043298.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_043299.1 Essential for efficient processing of 16S rRNA YP_043300.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_043301.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_043302.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1218 YP_043303.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_043304.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_043305.1 catalyzes the interconversion of succinyl-CoA and succinate YP_043306.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_043307.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1223 YP_043308.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1224 YP_043309.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1225 YP_043310.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_043311.1 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine YP_043312.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1228 YP_043313.1 heat shock protein involved in degradation of misfolded proteins YP_043314.1 heat shock protein involved in degradation of misfolded proteins YP_043315.1 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor YP_043316.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_043317.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_043318.1 Catalyzes the phosphorylation of UMP to UDP YP_043319.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_043320.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_043321.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1237 YP_043322.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1238 YP_043323.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_043324.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity YP_043325.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_043326.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_043327.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1243 YP_043328.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1244 YP_043329.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_043330.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_043331.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_043332.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1248 YP_043333.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_043334.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1250 YP_043335.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1251 YP_043336.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1252 YP_043337.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1253 YP_043338.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1254 YP_043339.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1255 YP_043340.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1256 YP_043341.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1257 YP_043342.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1258 YP_043343.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1259 YP_043344.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1260 YP_043345.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_043346.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP YP_043348.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1264 YP_043349.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1265 YP_043350.1 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin YP_043351.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1267 YP_043352.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_043353.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1269 YP_043354.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1270 YP_043355.1 This protein performs the mismatch recognition step during the DNA repair process YP_043356.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_043357.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1273 YP_043358.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1273a; Doubtful CDS. No significant database hits YP_043359.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1274 YP_043360.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_043361.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1276 YP_043362.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1277 YP_043363.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_043364.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1279 YP_043365.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1280 YP_043366.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1281 YP_043367.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1282 YP_043368.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1283 YP_043369.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1284 YP_043370.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1285 YP_043371.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1302 YP_043372.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1303 YP_043373.1 Doubtful CDS. No database matches YP_043374.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1311 YP_043375.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1314 YP_043376.1 Poor database matches. Weakly similar to the N-terminal region of mycobacteriophage TM4 protein Gp8 SWALL:Q9ZX69 (EMBL:AF068845) (186 aa) fasta scores: E(): 1.9, 37.83% id in 74 aa YP_043379.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1317 YP_043380.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1325b; Poor database matches. Similar to Bacillus anthracis conserved domain protein BA3762 SWALL:Q81XZ9 (EMBL:AE017035) (40 aa) fasta scores: E(): 1, 39.39% id in 33 aa YP_043381.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1326 YP_043382.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1327 YP_043383.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1328 YP_043384.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1329 YP_043385.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1330 YP_043386.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1331 YP_043387.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1332 YP_043388.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1333 YP_043389.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1334 YP_043390.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1335 YP_043391.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1336 YP_043392.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive YP_043393.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_043394.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_043395.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_043396.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1341 YP_043397.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1342 YP_043398.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1343 YP_043399.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1344 YP_043400.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_043401.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_043402.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1347 YP_043403.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1348 YP_043404.1 Represses a number of genes involved in the response to DNA damage YP_043405.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1350 YP_043406.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1351 YP_043407.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1352 YP_043408.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1353 YP_043409.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1355 YP_043410.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1356 YP_043411.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1357 YP_043412.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_043413.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1361 YP_043414.1 Catalyzes the conversion of citrate to isocitrate YP_043415.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1363 YP_043416.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1364 YP_043417.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1365 YP_043418.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_043419.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_043420.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1368 YP_043421.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1369 YP_043422.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1370 YP_043423.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1371 YP_043424.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1372 YP_043425.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_043426.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1374 YP_043427.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1376 YP_043428.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1377 YP_043429.1 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate YP_043430.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1379 YP_043431.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_043432.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1381 YP_043433.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_043434.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_043435.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_043436.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_043437.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_043438.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1387 YP_043439.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1388 YP_043441.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1391 YP_043442.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1392 YP_043443.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1393 YP_043444.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1394 YP_043445.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1395 YP_043446.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1396 YP_043447.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1397 YP_043448.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1398 YP_043449.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_043450.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1400 YP_043451.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1401 YP_043452.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1402 YP_043453.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1403 YP_043454.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1404 YP_043455.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_043456.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1406 YP_043457.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_043458.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_043459.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1409 YP_043460.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1410 YP_043461.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1411 YP_043462.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1412 YP_043463.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1413 YP_043464.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1414 YP_043465.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1415 YP_043466.1 catalyzes the hydrolysis of acylphosphate YP_043467.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1417 YP_043468.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1418 YP_043469.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1419 YP_043470.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1420 YP_043471.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1421 YP_043472.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1422 YP_043473.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1423 YP_043474.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_043475.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_043476.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1426 YP_043477.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1427 YP_043478.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1428; Doubtful CDS. No significant database hits YP_043479.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1429 YP_043480.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_043481.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1431 YP_043482.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1432 YP_043483.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1434 YP_043484.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1435 YP_043485.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_043486.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_043487.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1438 YP_043488.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1439 YP_043489.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_043490.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1441 YP_043491.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1442 YP_043492.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1443; Similar to the N-terminal region of Bacillus halodurans hypothetical protein BH1718 SWALL:Q9KC56 (EMBL:AP001512) (380 aa) fasta scores: E(): 1.4e-09, 42.16% id in 83 aa. Possible gene remnant YP_043493.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1444 YP_043494.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1445 YP_043495.1 Doubtful CDS. No database matches YP_043496.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1446 YP_043497.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1448 YP_043498.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1449 YP_043499.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic YP_043500.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1451 YP_043501.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1452 YP_043502.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1453 YP_043503.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1454 YP_043504.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1455 YP_043505.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1456 YP_043506.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1457 YP_043507.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1458 YP_043508.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1459 YP_043509.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1459a; No significant database matches YP_043510.1 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC YP_043511.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1461 YP_043512.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1462 YP_043513.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1463 YP_043514.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1464 YP_043515.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_043516.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1466 YP_043517.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1467 YP_043518.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity YP_043519.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1469 YP_043520.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1470 YP_043521.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1471 YP_043522.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1472 YP_043523.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1473 YP_043524.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1474 YP_043525.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_043526.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_043527.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_043528.1 Doubtful CDS. No database matches YP_043529.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_043530.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1479 YP_043531.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_043532.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1481 YP_043533.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1482 YP_043534.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_043535.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_043536.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_043537.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_043538.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1487 YP_043539.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1488 YP_043540.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1489 YP_043541.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1490 YP_043542.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1491 YP_043543.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1492 YP_043544.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1493 YP_043545.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1565 YP_043547.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1495 YP_043548.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1563; No significant database matches YP_043550.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1567 YP_043551.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1568 YP_043552.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1569 YP_043553.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1570 YP_043554.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1571 YP_043555.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1572 YP_043556.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1573 YP_043557.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1574 YP_043558.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1575 YP_043559.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1576 YP_043560.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1577 YP_043561.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1578 YP_043562.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1579 YP_043563.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1581 YP_043564.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_043565.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1583 YP_043566.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1584 YP_043567.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1585 YP_043568.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1586 YP_043569.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_043570.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1590 YP_043571.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1591 YP_043572.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1592 YP_043573.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1593 YP_043574.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1594 YP_043575.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1595 YP_043576.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1596 YP_043577.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1597 YP_043578.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_043579.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1599 YP_043580.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_043581.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_043582.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_043583.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1603 YP_043584.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_043585.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1605 YP_043586.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_043587.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1607 YP_043588.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1608 YP_043589.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1609 YP_043590.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1610 YP_043591.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1611 YP_043592.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein YP_043593.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein YP_043594.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_043595.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1615 YP_043596.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1616 YP_043597.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1617 YP_043598.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1618 YP_043599.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1619 YP_043600.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1620 YP_043601.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1621 YP_043602.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1622 YP_043603.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1623 YP_043604.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1624 YP_043605.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1625 YP_043606.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1626 YP_043607.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1627 YP_043608.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_043609.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1629 YP_043610.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1630 YP_043611.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1631 YP_043612.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1632 YP_043613.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1633 YP_043614.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_043615.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1635 YP_043616.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1636 YP_043617.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1637 YP_043618.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium YP_043619.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1639 YP_043620.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1640 YP_043621.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_043622.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1643 YP_043623.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_043624.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1645 YP_043625.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1646 YP_043626.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1647 YP_043627.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1648 YP_043628.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1649 YP_043629.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1650 YP_043630.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1651 YP_043631.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_043632.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1653 YP_043633.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_043634.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_043635.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_043636.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_043637.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_043638.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1659 YP_043639.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_043640.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_043641.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_043642.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_043643.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1665 YP_043644.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1666 YP_043645.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1667 YP_043646.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1668 YP_043647.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1669 YP_043648.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1670 YP_043649.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1671 YP_043650.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1672 YP_043651.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1673 YP_043652.1 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis YP_043653.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1675 YP_043654.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1676 YP_043655.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1677 YP_043656.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1679 YP_043657.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1682 YP_043658.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1683 YP_043659.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1684 YP_043660.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1685 YP_043661.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1686 YP_043662.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1687 YP_043663.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1688 YP_043664.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_043665.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_043666.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1691 YP_043667.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1692 YP_043668.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1693 YP_043669.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1694 YP_043670.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_043671.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1696 YP_043672.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_043673.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1698 YP_043674.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1699 YP_043675.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_043676.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1702 YP_043677.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1703 YP_043678.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1704 YP_043679.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1705 YP_043680.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1706 YP_043681.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1707 YP_043682.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1708 YP_043683.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1709 YP_043684.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_043685.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_043686.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1712 YP_043687.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_043688.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1714 YP_043689.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_043690.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1716 YP_043691.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_043692.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1718 YP_043693.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_043694.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_043695.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_043696.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_043697.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1723 YP_043698.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_043699.1 involved in the peptidyltransferase reaction during translation YP_043700.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1726 YP_043701.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1727 YP_043702.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1728 YP_043703.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_043704.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1729a; Doubtful CDS. No database matches YP_043705.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1730 YP_043706.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1731 YP_043707.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1732 YP_043708.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_043709.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1741 YP_043710.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1742 YP_043711.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_043712.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1744 YP_043713.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1745 YP_043714.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1746 YP_043715.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_043716.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_043717.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1749 YP_043718.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_043719.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1751 YP_043720.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_043721.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_043722.1 binds and unfolds substrates as part of the ClpXP protease YP_043723.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_043724.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1756 YP_043725.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1757 YP_043726.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_043727.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1759 YP_043728.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_043729.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1761 YP_043730.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_043731.1 Primosomal protein that may act to load helicase DnaC during DNA replication YP_043732.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1764 YP_043733.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1765 YP_043734.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1766 YP_043735.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_043736.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1768 YP_043737.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1769 YP_043738.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1770 YP_043739.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1771 YP_043740.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1772 YP_043741.1 Converts isocitrate to alpha ketoglutarate YP_043742.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate YP_043743.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1775 YP_043744.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1776 YP_043745.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_043746.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_043747.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_043748.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1780 YP_043749.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1781 YP_043750.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1782 YP_043751.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1783 YP_043752.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1784 YP_043753.1 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins YP_043754.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1786 YP_043755.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1787 YP_043756.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1788 YP_043757.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_043758.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1790 YP_043759.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_043760.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1792 YP_043761.1 Required for the synthesis of the thiazole moiety YP_043762.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1794 YP_043763.1 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation YP_043764.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1796 YP_043765.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_043766.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1798 YP_043767.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1799 YP_043768.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1800 YP_043769.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_043770.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1802 YP_043771.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1803 YP_043772.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1804 YP_043773.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1805 YP_043774.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1806 YP_043775.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1807; Possible gene remnant. Similar to the N-terminal region of Bacillus subtilis penicillin-binding protein 1A/1B PonA or BSU22320 SWALL:PBPA_BACSU (SWALL:P39793) (914 aa) fasta scores: E(): 9e-15, 31.86% id in 273 aa, and to Enterococcus faecalis penicillin-binding protein 1B, EF1740 SWALL:Q834C6 (EMBL:AE016952) (803 aa) fasta scores: E(): 1e-32, 37.5% id in 304 aa. Full length CDS is similar to Staphylococcus epidermidis SgtA protein SE1407 SWALL:Q8CNW0 (EMBL:AE016748) (301 aa) fasta scores: E(): 1.7e-69, 63.3% id in 297 aa YP_043776.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1809 YP_043777.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1809a; Doubtful CDS YP_043778.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_043779.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_043780.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1812 YP_043781.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1813 YP_043782.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1814 YP_043783.1 catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate YP_043784.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1816 YP_043785.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1817 YP_043786.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_043787.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1819 YP_043788.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1820 YP_043789.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1821 YP_043790.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1822 YP_043791.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1823 YP_043792.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1824 YP_043793.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1825 YP_043794.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_043795.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1834 YP_043796.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1835 YP_043797.1 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases YP_043798.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1837 YP_043799.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1838 YP_043800.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1839 YP_043801.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1840 YP_043802.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1841 YP_043803.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1842 YP_043804.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_043805.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1844 YP_043806.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1845 YP_043807.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1846 YP_043808.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1847 YP_043809.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1848 YP_043810.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1849 YP_043811.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_043812.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1851 YP_043813.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_043814.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1853 YP_043815.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1854 YP_043816.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1855 YP_043817.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1856 YP_043818.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1857 YP_043819.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1858 YP_043820.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1859 YP_043821.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1860 YP_043822.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1861 YP_043823.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_043824.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1865 YP_043825.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_043826.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1867 YP_043827.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0402; Doubtful CDS. No significant database matches YP_043828.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1868 YP_043829.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1869 YP_043830.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_043831.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_043832.1 Doubtful CDS. No database matches YP_043833.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1873 YP_043834.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1874 YP_043835.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1875 YP_043836.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1876 YP_043837.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1877 YP_043838.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1878 YP_043839.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1879 YP_043840.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1880 YP_043841.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1881 YP_043842.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1882 YP_043843.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1883 YP_043844.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1885; CDS is truncated at the C-terminus in comparison to SAR1885 YP_043845.1 Poor database matches. Similar to an internal region of Lactococcus lactis hypothetical lactococcin 972 immunity protein LclB SWALL:Q9L651 (EMBL:AF242367) (648 aa) fasta scores: E(): 0.94, 34.54% id in 55 aa. Possible gene remnant YP_043848.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0433 YP_043849.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1900 YP_043850.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1906 YP_043851.1 C-terminus is similar to the C-terminal regions of Staphylococcus aureus exfoliative toxin A precursor Eta SWALL:ETA_STAAU (SWALL:P09331) (280 aa) fasta scores: E(): 2.3e-11, 32.7% id in 211 aa, and to Staphylococcus hyicus exfoliative toxin B SWALL:Q9KWH0 (EMBL:AB036767) (268 aa) fasta scores: E(): 8.7e-09, 32.65% id in 196 aa YP_043852.1 Similar to Staphylococcus aureus exfoliative toxin B precursor Etb SWALL:ETB_STAAU (SWALL:P09332) (277 aa) fasta scores: E(): 1.9e-06, 32.88% id in 225 aa YP_043854.1 Similar to Staphylococcus aureus pathogenicity island 3 Ear protein SWALL:Q93CE4 (EMBL:AF410775) (185 aa) fasta scores: E(): 2.8e-19, 42.1% id in 190 aa YP_043855.1 Similar to Staphylococcus epidermidis ABC transporter subunit EpiG SWALL:Q54004 (EMBL:U77778) (230 aa) fasta scores: E(): 7.1e-42, 49.34% id in 229 aa, and to Streptococcus mutans MutG protein smu.657 SWALL:Q8DV51 (EMBL:AE014909) (248 aa) fasta scores: E(): 0.00014, 22.67% id in 247 aa YP_043856.1 Similar to Staphylococcus epidermidis ABC transporter subunit EpiE SWALL:Q54003 (EMBL:U77778) (254 aa) fasta scores: E(): 6.6e-51, 51.19% id in 252 aa, and to Bacillus subtilis Spa E SWALL:Q93GH0 (EMBL:AF233755) (251 aa) fasta scores: E(): 2.8e-11, 22.85% id in 245 aa YP_043857.1 Similar to Streptococcus pyogenes lantibiotic transport ATP-binding protein SrtF or spy1085 SWALL:SRTF_STRPY (SWALL:Q9FDU7) (229 aa) fasta scores: E(): 1.3e-32, 48.85% id in 219 aa, and to Staphylococcus epidermidis ABC transporter subunit EpiF SWALL:Q54002 (EMBL:U77778) (231 aa) fasta scores: E(): 2.2e-54, 72.88% id in 225 aa YP_043858.1 Similar to Staphylococcus epidermidis epidermin leader peptide processing serine protease EpiP precursor epiP SWALL:EPIP_STAEP (SWALL:P30199) (461 aa) fasta scores: E(): 3.1e-77, 49.24% id in 461 aa, and to an internal region of Lactococcus lactis nisin leader peptide processing serine protease precursor NisP SWALL:NISP_LACLA (SWALL:Q07596) (682 aa) fasta scores: E(): 3.7e-46, 36.52% id in 449 aa YP_043859.1 Similar to Staphylococcus epidermidis epidermin modifying enzyme EpiD SWALL:EPID_STAEP (SWALL:P30197) (181 aa) fasta scores: E(): 2.5e-36, 53.48% id in 172 aa, and to Streptococcus mutans MutD protein SWALL:Q9RPL6 (EMBL:AF154675) (188 aa) fasta scores: E(): 1.2e-17, 39.02% id in 164 aa YP_043860.1 Similar to Staphylococcus epidermidis epidermin biosynthesis protein EpiC SWALL:EPIC_STAEP (SWALL:P30196) (455 aa) fasta scores: E(): 1.8e-70, 46.71% id in 411 aa, and to Streptococcus mutans MutC protein SWALL:Q9RPL7 (EMBL:AF154675) (424 aa) fasta scores: E(): 1.2e-38, 32.47% id in 425 aa YP_043861.1 Similar to Staphylococcus epidermidis epidermin biosynthesis protein EpiB SWALL:EPIB_STAEP (SWALL:P30195) (986 aa) fasta scores: E(): 3.1e-127, 45.08% id in 996 aa, and to Bacillus subtilis subtilin biosynthesis protein SpaB or SpaD or spaE SWALL:SPAB_BACSU (SWALL:P39774) (1030 aa) fasta scores: E(): 2.8e-43, 25.95% id in 1044 aa YP_043862.1 Similar to Staphylococcus gallinarum lantibiotic gallidermin precursor GdmA SWALL:LANG_STAGA (SWALL:P21838) (52 aa) fasta scores: E(): 1.7e-09, 64.44% id in 45 aa, and to Staphylococcus epidermidis lantibiotic epidermin precursor EpiA SWALL:LANE_STAEP (SWALL:P08136) (52 aa) fasta scores: E(): 1.1e-08, 61.36% id in 44 aa YP_043863.1 Similar to Staphylococcus gallinarum lantibiotic gallidermin precursor GdmA SWALL:LANG_STAGA (SWALL:P21838) (52 aa) fasta scores: E(): 3.1e-07, 51.11% id in 45 aa, and to Staphylococcus epidermidis lantibiotic epidermin precursor EpiA SWALL:LANE_STAEP (SWALL:P08136) (52 aa) fasta scores: E(): 1.4e-06, 50% id in 44 aa YP_043864.1 Similar to Staphylococcus aureus gamma-hemolysin component B precursor HlgB SWALL:HLGB_STAAN (SWALL:Q07226) (325 aa) fasta scores: E(): 9.7e-96, 75.92% id in 324 aa YP_043865.1 Similar to Staphylococcus aureus gamma-hemolysin component A precursor HlgA or Hlg2 SWALL:HLGA_STAAM (SWALL:P31714) (309 aa) fasta scores: E(): 5.4e-84, 70.87% id in 309 aa YP_043867.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1914; Poor database matches. Weakly similar to the N-terminal region of Plasmodium falciparum hypothetical protein PF11_0387 SWALL:Q8IHY9 (EMBL:AE014841) (551 aa) fasta scores: E(): 1, 23.89% id in 272 aa YP_043868.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1922 YP_043869.1 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX YP_043870.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_043871.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_043872.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1926 YP_043873.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1927 YP_043874.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1928 YP_043875.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1929 YP_043876.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1930 YP_043877.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1930a; Similar to the N-terminal regions of Clostridium acetobutylicum hypothetical protein CAC0828 cac0828 SWALL:Q97KT8 (EMBL:AE007598) (308 aa) fasta scores: E(): 2, 32.3% id in 65 aa. Weakly similar to the N-terminal region of Clostridium tetani hypothetical protein ctp43 SWALL:Q899X2 (EMBL:AF528097) (142 aa) fasta scores: E(): 7, 23.63% id in 55 aa YP_043878.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1931 YP_043879.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1932 YP_043880.1 catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates YP_043881.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1934 YP_043882.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1935 YP_043883.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1936 YP_043884.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1937 YP_043885.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1938 YP_043886.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1939 YP_043887.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1940 YP_043888.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1941 YP_043889.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_043890.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1943 YP_043891.1 Doubtful CDS. No significant database matches YP_043893.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1944 YP_043894.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1945 YP_043895.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1946 YP_043896.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1947 YP_043897.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1948 YP_043898.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1949 YP_043899.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1950 YP_043900.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1951 YP_043901.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1952 YP_043902.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1953 YP_043903.1 converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate YP_043904.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1955 YP_043905.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1956 YP_043906.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1957 YP_043907.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1958 YP_043908.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1959 YP_043909.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1960 YP_043910.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1961 YP_043911.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1962 YP_043912.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_043913.1 monofunctional; catalyzes the elongation of glycan strands in cell wall biosynthesis YP_043914.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1965 YP_043915.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1966 YP_043916.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1967 YP_043917.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1968 YP_043918.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1969 YP_043919.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1970 YP_043920.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1971 YP_043921.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1972 YP_043922.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1973 YP_043923.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1974 YP_043924.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1975 YP_043925.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1976 YP_043926.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1977 YP_043927.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_043928.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1980 YP_043929.1 Doubtful CDS. No database matches YP_043930.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1981 YP_043931.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1982 YP_043932.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1983 YP_043933.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1984 YP_043934.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1985 YP_043935.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_043936.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1987 YP_043937.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1988 YP_043938.1 similar to YegS from E. coli YP_043939.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_043940.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_043941.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_043942.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1994 YP_043943.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1995 YP_043944.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1996 YP_043945.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1997 YP_043946.1 PcrB-like protein; GGGP synthase; member of prenyltransferases that transfer isoprenoid groups to nonisoprenoid acceptors; functions in form GGGP from glycerol-1-phosphate (G-1-P) and geranylgeranyl pyrophosphate (GGPP); important in lipid metabolism and especially important as the ether linkages in archaea are different than those in bacteria; GGGP synthase lies at the branch point for membrane lipid biosynthesis; cytosolic; T acidophilum protein acts as a homodimer while M thermoautotrophicum protein has been reported to function as a pentamer YP_043947.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1999 YP_043948.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_043949.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2001 YP_043950.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2002 YP_043951.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2003 YP_043952.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2004 YP_043953.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_043954.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate YP_043955.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2007 YP_043956.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2008 YP_043957.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2009 YP_043958.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2010 YP_043959.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2011 YP_043960.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_043961.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2013 YP_043962.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2014 YP_043963.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2015 YP_043964.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2016 YP_043965.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2017 YP_043966.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2018 YP_043967.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2019 YP_043968.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2020 YP_043969.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2021 YP_043970.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2022 YP_043971.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2023 YP_043972.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2024 YP_043973.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2025 YP_043974.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2026 YP_043975.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2027 YP_043976.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2027a; Doubtful CDS. No database matches YP_043977.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2028 YP_043978.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2032 YP_043979.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2033 YP_043981.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2035 YP_043982.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2039 YP_043983.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2040; Similar to the N-terminal region of Staphylococcus aureus autolysin LytA SWALL:ALYS_STAAU (SWALL:P24556) (481 aa) fasta scores: E(): 2.7e-07, 29.23% id in 260 aa, and to the full length Staphylococcus aureus phage phi 13 amidase SWALL:Q8SDJ9 (EMBL:AF424783) (251 aa) fasta scores: E(): 6.1e-108, 99.6% id in 251 aa. Possible gene remnant YP_043984.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2041 YP_043985.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2042 YP_043986.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2043 YP_043987.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2045 YP_043988.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2046 YP_043989.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2047 YP_043990.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2048 YP_043991.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2049 YP_043992.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2050 YP_043993.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2051 YP_043994.1 Identical to Staphylococcus aureus phage phi 13, and Staphylococcus aureus prophage phiPV83 phi PVL orf 14-like protein SWALL:Q9MBP3 (EMBL:AF424783) (148 aa) fasta scores: E(): 1.5e-49, 100% id in 148 aa YP_043995.1 Identical to Staphylococcus aureus phage phi 13 phi PVL orf 13-like protein SWALL:Q8SDK5 (EMBL:AF424783) (317 aa) fasta scores: E(): 7.8e-115, 100% id in 317 aa YP_043996.1 Highly similar to Staphylococcus aureus phage phi 13 phi PVL orf 12-like protein SWALL:Q8SDK6 (EMBL:AF424783) (126 aa) fasta scores: E(): 2.7e-49, 99.2% id in 126 aa YP_043997.1 Identical to Staphylococcus aureus phage phi 13, and Staphylococcus aureus prophage phiPV83 phi PVL orf 11-like protein SWALL:Q9MBP6 (EMBL:AF424783) (125 aa) fasta scores: E(): 2.5e-46, 100% id in 125 aa YP_043998.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2058 YP_043999.1 Identical to Staphylococcus aureus prophage phiPV83 orf 44a SWALL:Q9MBP8 (EMBL:AB044554) (113 aa) fasta scores: E(): 8.9e-44, 100% id in 109 aa YP_044000.1 Identical to Staphylococcus aureus bacteriophage PVL, Staphylococcus aureus prophage phiPV83, and Staphylococcus aureus phage phi 13 orf 8 SWALL:O80047 (EMBL:AB009866) (52 aa) fasta scores: E(): 3e-17, 100% id in 52 aa YP_044001.1 Almost identical to Staphylococcus aureus phage phi 13 head protein SWALL:Q8SDK8 (EMBL:AF424783) (415 aa) fasta scores: E(): 1.8e-134, 99.75% id in 415 aa YP_044002.1 Identical to Staphylococcus aureus phage phi 13, and Staphylococcus aureus prophage phiPV83 prohead protease SWALL:Q9MBP9 (EMBL:AF424783) (194 aa) fasta scores: E(): 1.7e-73, 100% id in 194 aa YP_044003.1 Identical to Staphylococcus aureus bacteriophage PVL portal protein SWALL:O80043 (EMBL:AB009866) (416 aa) fasta scores: E(): 2.8e-159, 100% id in 416 aa YP_044004.1 Almost identical to Staphylococcus aureus prophage phiPV83 phi PVL orf 3 homologue SWALL:Q9MBQ1 (EMBL:AB044554) (66 aa) fasta scores: E(): 3.2e-23, 98.48% id in 66 aa YP_044005.1 Identical to Staphylococcus aureus phage phi 13, and Staphylococcus aureus prophage phiPV83 terminase-large subunit SWALL:Q9MBQ2 (EMBL:AF424783) (564 aa) fasta scores: E(): 0, 100% id in 564 aa YP_044006.1 Identical to Staphylococcus aureus bacteriophage PVL, Staphylococcus aureus prophage phiPV83, and Staphylococcus aureus phage phi 13 orf 4 like protein SWALL:O80040 (EMBL:AB009866) (155 aa) fasta scores: E(): 8.7e-56, 100% id in 155 aa YP_044007.1 Identical to Staphylococcus aureus prophage phiPV83 phi PVL orf 63 homologue SWALL:Q9MBQ3 (EMBL:AB044554) (117 aa) fasta scores: E(): 3.8e-50, 100% id in 117 aa YP_044008.1 Almost identical to Staphylococcus aureus prophage phiPV83 phi PVL orf 62 homologue SWALL:Q9MBQ4 (EMBL:AB044554) (150 aa) fasta scores: E(): 1.9e-52, 98.66% id in 150 aa YP_044009.1 Highly similar to Staphylococcus aureus prophage phiPV83 phi PVL orf 61 homologue SWALL:Q9MBQ5 (EMBL:AB044554) (153 aa) fasta scores: E(): 2e-48, 94.77% id in 153 aa YP_044010.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2068 YP_044011.1 Identical to Staphylococcus aureus bacteriophage PVL orf 59 SWALL:O80097 (EMBL:AB009866) (216 aa) fasta scores: E(): 1.2e-74, 100% id in 216 aa YP_044012.1 Identical to Staphylococcus aureus bacteriophage PVL orf 58 SWALL:O80096 (EMBL:AB009866) (50 aa) fasta scores: E(): 1e-18, 100% id in 50 aa YP_044013.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2069 YP_044014.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2078 YP_044015.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2080 YP_044016.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2082 YP_044017.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2083 YP_044018.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2084 YP_044019.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2085 YP_044020.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2086 YP_044021.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2087 YP_044022.1 Identical to Staphylococcus aureus phage phi 13 phi PVL orf 39-like protein SWALL:Q8SDM6 (EMBL:AF424783) (86 aa) fasta scores: E(): 1.5e-31, 100% id in 86 aa YP_044023.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2091 YP_044024.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2092 YP_044025.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2093 YP_044026.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2094 YP_044027.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2095 YP_044028.1 Almost identical to Staphylococcus aureus phage phi 13 phi PVL orf 33-like protein SWALL:Q8SDN0 (EMBL:AF424783) (179 aa) fasta scores: E(): 1.1e-70, 99.44% id in 179 aa YP_044029.1 Amost identical to Staphylococcus aureus phage phi 13 phi PVL orf 32-like protein SWALL:Q8SDN1 (EMBL:AF424783) (93 aa) fasta scores: E(): 5.8e-32, 98.92% id in 93 aa. Possible alternative translational start site YP_044030.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1555 YP_044031.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2100 YP_044032.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1920 YP_044033.1 Ortholog of S. aureus MRSA252 (BX571856) SAR1919 YP_044034.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2105 YP_044035.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2107 YP_044036.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2108 YP_044037.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_044038.1 Similar to Streptomyces glaucescens tetracenomycin polyketide synthesis O-methyltransferase TcmP SWALL:TCMP_STRGA (SWALL:P39887) (270 aa) fasta scores: E(): 4.3e-11, 25.1% id in 243 aa, and to Methanosarcina acetivorans hypothetical protein ma3472 SWALL:Q8TKD5 (EMBL:AE011055) (274 aa) fasta scores: E(): 5.7e-24, 39.63% id in 270 aa YP_044039.1 Similar to Bacillus subtilis ferrichrome-binding protein precursor fhud or bsu33320 SWALL:FHUD_BACSU (SWALL:P37580) (315 aa) fasta scores: E(): 5.7e-29, 38.66% id in 300 aa, and to Clostridium acetobutylicum ferrichrome-binding periplasmic proteinl, fhud cac0790 SWALL:Q97KX6 (EMBL:AE007594) (307 aa) fasta scores: E(): 4.4e-31, 37.71% id in 297 aa YP_044040.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2111 YP_044041.1 Similar to Streptococcus agalactiae acetyltransferase, GNAT family sag0999 SWALL:Q8DZU8 (EMBL:AE014237) (143 aa) fasta scores: E(): 2.3e-10, 30.76% id in 130 aa, and to Rickettsia conorii similarity to histon and other protein acetyltransferase rc0741 SWALL:Q92HN0 (EMBL:AE008631) (149 aa) fasta scores: E(): 1.8e-07, 29.85% id in 134 aa YP_044043.1 Ortholog of S. aureus MRSA252 (BX571856) SAR0382 YP_044044.1 Poor database matches. Weakly similar to C-terminal region of Bacillus subtilis YjcO protein SWALL:O31637 (EMBL:Z99110) (153 aa) fasta scores: E(): 0.56, 25% id in 60 aa YP_044045.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_044046.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_044047.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2118 YP_044048.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2119 YP_044049.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2120 YP_044050.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2121 YP_044051.1 Lyses erythrocytes and other mammalian cells YP_044052.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2123 YP_044053.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2124 YP_044054.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2125 YP_044055.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2126 YP_044056.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2127 YP_044057.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2128 YP_044058.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2129 YP_044059.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2130 YP_044060.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2131 YP_044061.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2132 YP_044062.1 modulates transcription in response to the NADH/NAD(+) redox state YP_044063.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2134 YP_044064.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2135 YP_044065.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_044066.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2137 YP_044067.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2138 YP_044068.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2139 YP_044069.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_044070.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2141 YP_044071.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_044072.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_044073.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_044074.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_044075.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_044076.1 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic YP_044077.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2150 YP_044078.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2151 YP_044079.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase YP_044080.1 binds to sigma-B preventing the formation of an RNA polymerase holoenzyme YP_044081.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2154 YP_044082.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2155 YP_044083.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2156 YP_044084.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2157 YP_044085.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2158 YP_044086.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_044087.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2160 YP_044088.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2161 YP_044089.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2162 YP_044090.1 one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex YP_044091.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_044092.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_044093.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2166 YP_044094.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2167 YP_044095.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2168 YP_044096.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2169 YP_044097.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_044098.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2171 YP_044099.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2173 YP_044100.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2174 YP_044101.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2175 YP_044102.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2177 YP_044103.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2178 YP_044104.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2179 YP_044105.1 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate YP_044106.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_044107.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_044108.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2183 YP_044109.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2183b; Doubtful CDS. No database matches YP_044110.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2184 YP_044111.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2185 YP_044112.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2186 YP_044113.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_044114.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_044115.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2189 YP_044116.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_044117.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_044118.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_044119.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_044120.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_044121.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit B is part of the membrane proton channel YP_044122.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_044123.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_044124.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2198 YP_044125.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2199 YP_044126.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_044127.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_044128.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2202 YP_044129.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2203 YP_044130.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2204 YP_044131.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2205 YP_044132.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_044133.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_044134.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_044135.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_044136.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2210 YP_044137.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2211 YP_044138.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_044139.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; induced by anaerobic conditions in Bacillus subtilis YP_044140.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2214 YP_044141.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_044142.1 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling YP_044143.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2217 YP_044144.1 catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type II pantothenate kinases are not regulated by feedback inhibition by coenzyme A YP_044145.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2219 YP_044146.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2220 YP_044147.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2221 YP_044148.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_044149.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2223 YP_044150.1 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway YP_044151.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_044152.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_044153.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2227 YP_044154.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2228 YP_044155.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2229 YP_044156.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2230 YP_044157.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2231 YP_044158.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2232 YP_044159.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2233 YP_044160.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2234 YP_044161.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2235 YP_044163.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2239; Doubtful CDS. No database matches YP_044164.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2240 YP_044165.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2241 YP_044166.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_044167.1 Doubtful CDS. No significant database hits YP_044168.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2244 YP_044169.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2245 YP_044170.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2246 YP_044171.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2247 YP_044172.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_044173.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2253 YP_044174.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2254 YP_044175.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2255 YP_044176.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2256 YP_044177.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2257 YP_044178.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2259 YP_044179.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2260 YP_044180.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2261 YP_044181.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2262 YP_044182.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2263 YP_044183.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2264 YP_044184.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2265 YP_044185.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2266 YP_044186.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2267 YP_044187.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2268 YP_044188.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2269 YP_044189.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2270 YP_044190.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2271 YP_044191.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2272 YP_044192.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2273 YP_044193.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2274 YP_044194.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2275 YP_044195.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2276 YP_044196.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2277 YP_044197.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2278 YP_044198.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2279 YP_044199.1 catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside YP_044200.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2281 YP_044201.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2282 YP_044202.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources YP_044203.1 catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP YP_044204.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate YP_044205.1 catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization YP_044206.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2287 YP_044207.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_044208.1 Doubtful CDS. No significant database hits YP_044209.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2289 YP_044210.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2289a; Doubtful CDS. No database matches YP_044211.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2290 YP_044212.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2291 YP_044213.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2292 YP_044214.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2295 YP_044215.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2296 YP_044216.1 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase YP_044217.1 Doubtful CDS YP_044218.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2297b; Doubtful CDS YP_044220.1 forms a direct contact with the tRNA during translation YP_044221.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_044222.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_044223.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2303 YP_044224.1 with CbiNQ forms the ABC transporter for cobalt import; Staphylococcus has two adjacent copies of this gene YP_044225.1 with CbiNQ forms the ABC transporter for cobalt import; Staphylococcus has two adjacent copies of this gene YP_044226.1 is a component of the macrolide binding site in the peptidyl transferase center YP_044227.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_044228.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_044229.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_044230.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_044231.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_044232.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_044233.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_044234.1 late assembly protein YP_044235.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_044236.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_044237.1 binds 5S rRNA along with protein L5 and L25 YP_044238.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_044239.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_044240.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif YP_044241.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_044242.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_044243.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_044244.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_044245.1 one of the stabilizing components for the large ribosomal subunit YP_044246.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_044247.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_044248.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_044249.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_044250.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_044251.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_044252.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_044253.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_044254.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_044255.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2337 YP_044256.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2338 YP_044257.1 decatenates replicating daughter chromosomes YP_044258.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2340 YP_044259.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2341 YP_044260.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2342 YP_044261.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2343 YP_044262.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2344 YP_044263.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2345 YP_044264.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2346 YP_044265.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2347 YP_044266.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2348 YP_044267.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2349 YP_044268.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2350 YP_044269.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2351 YP_044270.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2352 YP_044271.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_044272.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2354 YP_044273.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2355 YP_044274.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2356 YP_044275.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2357 YP_044276.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_044277.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2359 YP_044278.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2360 YP_044279.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2361 YP_044280.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2362 YP_044281.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2363 YP_044282.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_044283.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2365 YP_044284.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2366 YP_044285.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2367 YP_044286.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2368 YP_044287.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2369 YP_044288.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2370; Doubtful CDS. No significant database hits YP_044289.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2371 YP_044290.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter YP_044291.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Staphylococcus saprophyticus plays a role in bladder invasiveness and may induce the formation of kidney and bladder stones due to the alkalization of urine YP_044292.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_044293.1 involved in the assembly of the urease metallocenter; possible nickel donor YP_044294.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2376 YP_044295.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2377 YP_044296.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2378 YP_044297.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2379 YP_044298.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2380 YP_044299.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2381 YP_044300.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2382 YP_044301.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2383 YP_044302.1 Doubtful CDS. No significant database hits YP_044303.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2385 YP_044304.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2386 YP_044305.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2387 YP_044306.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2388 YP_044307.1 Doubtful CDS. No significant database matches YP_044308.1 Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor YP_044309.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2390 YP_044310.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2391 YP_044311.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2391a; Weakly similar to Clostridium acetobutylicum predicted membrane protein cac2051 SWALL:Q97HG0 (EMBL:AE007708) (92 aa) fasta scores: E(): 6.9, 25.35% id in 71 aa YP_044312.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2392 YP_044313.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2393 YP_044314.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2394 YP_044315.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2395 YP_044316.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2396 YP_044317.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2397 YP_044318.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2398 YP_044319.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2399 YP_044320.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2400 YP_044321.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2401 YP_044322.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2402 YP_044323.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2403 YP_044324.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2404 YP_044325.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2405 YP_044326.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2407 YP_044327.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2408 YP_044328.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2409 YP_044329.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2410 YP_044330.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2411 YP_044331.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2412 YP_044332.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2413 YP_044333.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2414 YP_044334.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_044335.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_044336.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2418 YP_044337.1 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate YP_044338.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2421 YP_044339.1 catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_044340.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2423 YP_044341.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2424 YP_044342.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2425 YP_044343.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2426 YP_044344.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2427 YP_044345.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2428 YP_044346.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2428a; Doubtful CDS YP_044347.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2428b; Doubtful CDS YP_044348.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2429 YP_044349.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2430 YP_044350.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate YP_044351.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2432 YP_044352.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2433 YP_044353.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2434 YP_044354.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2435 YP_044355.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2436 YP_044356.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2437 YP_044357.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2438 YP_044358.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2439 YP_044359.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2441 YP_044360.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2442 YP_044361.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2443 YP_044362.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2444 YP_044363.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2445 YP_044364.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2446 YP_044365.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2447 YP_044366.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2448 YP_044367.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2449 YP_044368.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2450 YP_044369.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_044370.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2455 YP_044371.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2456 YP_044372.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2457 YP_044373.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2458 YP_044374.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2459 YP_044376.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2460 YP_044377.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2461 YP_044378.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2462 YP_044379.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2463 YP_044380.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2464 YP_044381.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2465 YP_044382.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2466 YP_044383.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2467 YP_044384.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2468 YP_044385.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2469 YP_044386.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2470 YP_044387.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2472 YP_044388.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2473 YP_044389.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2474 YP_044390.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2475 YP_044391.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2476 YP_044392.1 Doubtful CDS YP_044393.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2478 YP_044394.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2480 YP_044395.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2481 YP_044396.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2482 YP_044397.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2483 YP_044398.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2484 YP_044399.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2485 YP_044400.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2486 YP_044401.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2487 YP_044402.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2488 YP_044403.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2489 YP_044404.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2490 YP_044405.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2491 YP_044406.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2493 YP_044407.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2494 YP_044408.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2495 YP_044409.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2496 YP_044410.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2497 YP_044411.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2498 YP_044412.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2499 YP_044413.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2500 YP_044414.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2501 YP_044415.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2502 YP_044416.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2503 YP_044417.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2504 YP_044418.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2505 YP_044419.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_044420.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2507 YP_044421.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2508 YP_044422.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2509 YP_044423.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2510 YP_044424.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2511 YP_044425.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2512 YP_044426.1 catalyzes the formation of pimeloyl-CoA from pimelate and coenzyme A YP_044427.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2514 YP_044428.1 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine YP_044429.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2516 YP_044430.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2517 YP_044431.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2518 YP_044432.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2519 YP_044433.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2519a; Doubtful CDS YP_044434.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2520 YP_044435.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2521 YP_044436.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2522 YP_044437.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2523 YP_044438.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2524 YP_044439.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2525 YP_044440.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2526 YP_044441.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2527 YP_044442.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2528 YP_044443.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2529 YP_044444.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2530 YP_044445.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2531 YP_044446.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2532 YP_044447.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_044448.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2534 YP_044449.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2535 YP_044450.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2536 YP_044451.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2537 YP_044452.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2538 YP_044453.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2539 YP_044454.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2540 YP_044455.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2541 YP_044456.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2542 YP_044457.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2543 YP_044458.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2544 YP_044459.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2545 YP_044460.1 Similar to Nitrosomonas europaea hypothetical protein ne1352 SWALL:Q82UW6 (EMBL:BX321860) (86 aa) fasta scores: E(): 4.4e-06, 36.9% id in 84 aa, and to Rickettsia sibirica hypothetical protein rsib_orf.415 SWALL:EAA25654 (EMBL:AABW01000001) (86 aa) fasta scores: E(): 2.7e-05, 37.64% id in 85 aa YP_044461.1 Similar to Rickettsia sibirica hypothetical protein rsib_orf.416 SWALL:EAA25655 (EMBL:AABW01000001) (80 aa) fasta scores: E(): 4.4e-05, 35.36% id in 82 aa, and to Synechococcus sp. WH 8102 hypothetical protein synw0576 SWALL:CAE07091 (EMBL:BX569690) (80 aa) fasta scores: E(): 0.00013, 38.46% id in 78 aa YP_044462.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2546 YP_044463.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2547 YP_044464.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2548 YP_044465.1 Doubtful CDS YP_044466.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2549 YP_044467.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2550 YP_044468.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2551 YP_044469.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2552 YP_044470.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2553 YP_044471.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2554 YP_044472.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2555 YP_044473.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2556 YP_044474.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2557 YP_044475.1 Poor database matches. Weakly similar to Helicobacter pylori hypothetical protein HP0060 SWALL:O24900 (EMBL:AE000528) (813 aa) fasta scores: E(): 1.9, 29.8% id in 104 aa YP_044476.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2559 YP_044477.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2560 YP_044478.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2561 YP_044480.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2563 YP_044481.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2565 YP_044482.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2566 YP_044483.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2567 YP_044484.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2568 YP_044485.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2569 YP_044487.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2570 YP_044488.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2573 YP_044489.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2574 YP_044490.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2575 YP_044491.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2576 YP_044492.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2577 YP_044493.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2578 YP_044494.1 Poor database matches. Weakly similar to Anabaena sp. hypothetical protein asr3368 SWALL:Q8YRS5 (EMBL:AP003592) (75 aa) fasta scores: E(): 5.3, 24.61% id in 65 aa YP_044495.1 Weakly similar to Enterococcus sp. 130, Staphylococcus aureus, Streptococcus intermedius, Streptococcus salivarius, Streptococcus sp. 6, and Streptococcus pneumoniae macrolide efflux protein E MefA or MefE SWALL:P95835 (EMBL:AY071835) (405 aa) fasta scores: E(): 2.7e-10, 22.22% id in 387 aa, and to Oceanobacillus iheyensis hypothetical conserved protein ob3168 SWALL:Q8ELQ1 (EMBL:AP004604) (401 aa) fasta scores: E(): 3.8e-20, 22.9% id in 393 aa YP_044496.1 N-terminal region is similar to an internal region Staphylococcus aureus methicillin-resistant surface protein precursor Pls SWALL:MRSP_STAAU (SWALL:P80544) (1637 aa) fasta scores: E(): 1.2e-173, 55.06% id in 1037 aa YP_044497.1 Similar to Staphylococcus aureus Staphylococcal accessory regulator SarA SWALL:Q53777 (EMBL:U46541) (113 aa) fasta scores: E(): 3.2e-09, 34.21% id in 114 aa, and to the N-terminal region of Clostridium perfringens probable transcriptional regulator cpe0789 SWALL:Q8XMA1 (EMBL:AP003188) (147 aa) fasta scores: E(): 0.12, 28.2% id in 117 aa YP_044498.1 Almost identical to Staphylococcus aureus Rot-like protein Rlp SWALL:Q9EZK4 (EMBL:AF288788) (247 aa) fasta scores: E(): 8.2e-90, 99.59% id in 247 aa. Similar to N-terminal region of Staphylococcus aureus staphylococcal accessory regulator A homolog SarR SWALL:Q9F0R1 (EMBL:AF207701) (115 aa) fasta scores: E(): 0.0028, 27.77% id in 108 aa YP_044499.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2579 YP_044500.1 Similar to Staphylococcus aureus fibronectin-binding protein precursor FnbA SWALL:FNBA_STAAU (SWALL:P14738) (1018 aa) fasta scores: E(): 1.5e-103, 66.95% id in 1026 aa YP_044501.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2580 YP_044502.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2581 YP_044503.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2582 YP_044504.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2583 YP_044505.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2584 YP_044506.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2585 YP_044507.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2586 YP_044508.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2587 YP_044509.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2588 YP_044510.1 Doubtful CDS YP_044511.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2589 YP_044512.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2590 YP_044513.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2594 YP_044514.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2595 YP_044515.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2596 YP_044517.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2597 YP_044518.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2598 YP_044519.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2599 YP_044520.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2600 YP_044521.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2601 YP_044522.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2603 YP_044523.1 catalyzes the formation of pyruvate from lactate YP_044524.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2607 YP_044525.1 Similar to Bacillus subtilis function unknown protein YydI SWALL:Q45593 (EMBL:D78193) (209 aa) fasta scores: E(): 1.3e-36, 61.42% id in 210 aa, and to Streptococcus agalactiae ABC transporter, ATP-binding protein sag2027 SWALL:Q8DX31 (EMBL:AE014283) (205 aa) fasta scores: E(): 1.9e-23, 44.01% id in 209 aa YP_044526.1 Similar to Bacillus subtilis function unknown protein YydJ SWALL:Q45592 (EMBL:D78193) (240 aa) fasta scores: E(): 4.7e-56, 61.66% id in 240 aa, and to Streptococcus agalactiae membrane protein, sag2026 SWALL:Q8DX32 (EMBL:AE014283) (240 aa) fasta scores: E(): 2.3e-33, 42.97% id in 242 aa YP_044527.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2608 YP_044528.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2609 YP_044529.1 Doubtful CDS YP_044530.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2610 YP_044531.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2611 YP_044532.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2612 YP_044533.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2613 YP_044534.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2614 YP_044535.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2615 YP_044536.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2616 YP_044537.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2617 YP_044538.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2618 YP_044539.1 catalyzes the formation of acetyl phosphate from pyruvate YP_044540.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2620 YP_044541.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2621 YP_044542.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2622 YP_044543.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2623 YP_044544.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2624 YP_044545.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2625 YP_044546.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2626 YP_044547.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2627 YP_044548.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2628 YP_044549.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2629 YP_044550.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2630 YP_044551.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2631 YP_044552.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2632 YP_044553.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2633 YP_044554.1 catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate YP_044555.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2635 YP_044556.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2636 YP_044557.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2637 YP_044558.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2639 YP_044559.1 catalyzes the formation of pyruvate from lactate YP_044560.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2641 YP_044561.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2642 YP_044562.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2643 YP_044563.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2645 YP_044564.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2646 YP_044565.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2647 YP_044566.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2648 YP_044567.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2649 YP_044568.1 Similar to Bacillus cereus iaa acetyltransferase bc4682 SWALL:Q816X8 (EMBL:AE017013) (163 aa) fasta scores: E(): 6.5e-19, 40.38% id in 156 aa, and to Bacillus subtilis protease synthase and sporulation negative regulatory protein Pai 1 PaiA or bsu32150 SWALL:PAIA_BACSU (SWALL:P21340) (171 aa) fasta scores: E(): 0.11, 24.28% id in 140 aa YP_044569.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2650 YP_044570.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2651 YP_044572.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2652 YP_044573.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2653 YP_044574.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2654 YP_044575.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2655 YP_044576.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2656 YP_044577.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2657 YP_044578.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2658 YP_044579.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2659 YP_044580.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2660 YP_044581.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2661 YP_044582.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2662 YP_044583.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2663 YP_044584.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2664 YP_044585.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2665 YP_044586.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2666 YP_044587.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2667 YP_044588.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2668 YP_044589.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_044590.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2670 YP_044591.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2671 YP_044592.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2672 YP_044593.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2673 YP_044594.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2674 YP_044595.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_044596.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_044597.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_044598.1 catalyzes the formation of 2-dehydropantoate from (R)-pantoate YP_044599.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2679 YP_044600.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2680 YP_044601.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2681 YP_044602.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_044603.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2683 YP_044604.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis YP_044605.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_044606.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2686 YP_044607.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2687 YP_044608.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2688 YP_044609.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2689 YP_044610.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_044611.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2691 YP_044612.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2692 YP_044613.1 Poor database matches. Weakly similar to the C-terminal region of Prochlorococcus marinus subsp. marinus str. CCMP1375 metallo-beta-lactamase superfamily hydrolase GloB or pro1462 SWALL:AAQ00506 (EMBL:AE017165) (300 aa) fasta scores: E(): 5.4e-05, 24% id in 200 aa YP_044614.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2693 YP_044615.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2694 YP_044616.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_044617.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2696 YP_044618.1 catalyzes the formation of siroheme from precorrin-2 YP_044619.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2698 YP_044620.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2699 YP_044621.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2700 YP_044622.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2701 YP_044623.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2702 YP_044624.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2703 YP_044625.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2704 YP_044626.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2706 YP_044627.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2706a; Doubtful CDS YP_044628.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2707 YP_044629.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2708 YP_044630.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2709 YP_044631.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2710 YP_044632.2 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_044633.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2712 YP_044634.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway YP_044635.1 catalyzes the degradation of arginine to citruline and ammonia YP_044636.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2715 YP_044637.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2716 YP_044638.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2717 YP_044639.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2718 YP_044640.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2719 YP_044641.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2720 YP_044642.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2721 YP_044643.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2722 YP_044644.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2723 YP_044645.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2724 YP_044646.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2725 YP_044647.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2726 YP_044648.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2727 YP_044649.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins YP_044650.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2729 YP_044651.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2730 YP_044652.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2731 YP_044653.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_044654.1 Similar to internal region of Streptococcus gordonii platelet binding protein GspB SWALL:Q939N5 (EMBL:AY028381) (3072 aa) fasta scores: E(): 3.4e-130, 42.3% id in 2234 aa, and to Lactobacillus plantarum cell surface SD repeat protein precursor Sdr or lp_1303.1 or lp_1303A SWALL:Q88XB6 (EMBL:AL935255) (3360 aa) fasta scores: E(): 8e-119, 42.16% id in 2196 aa YP_044655.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2735 YP_044656.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2736 YP_044657.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2738 YP_044658.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2739 YP_044659.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2740 YP_044660.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; a fusion protein of this enzyme with MsrB provides protection against oxidative stress in Neisseria gonorrhoeae YP_044661.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2742 YP_044662.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2743 YP_044663.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2744 YP_044664.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2745 YP_044665.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2746 YP_044666.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein YP_044667.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2748 YP_044668.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2749 YP_044669.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2750 YP_044670.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2753 YP_044671.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_044672.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_044673.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-hosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_044674.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_044675.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_044676.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2759 YP_044677.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_044678.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_044679.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_044680.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2763 YP_044681.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2764 YP_044682.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2765 YP_044683.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2766 YP_044684.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2767 YP_044685.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2768 YP_044686.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2769 YP_044688.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2770 YP_044689.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2771 YP_044690.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline YP_044691.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2773 YP_044692.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2774 YP_044693.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2775 YP_044695.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2776 YP_044696.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2777 YP_044697.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2778 YP_044698.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2779 YP_044699.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2780 YP_044700.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2781 YP_044701.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2782 YP_044702.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2783; No significant database matches. Doubtful CDS YP_044703.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2790 YP_044704.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2791 YP_044705.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2792 YP_044706.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2793 YP_044707.1 Ortholog of S. aureus MRSA252 (BX571856) SAR2795 YP_044708.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_044709.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_044710.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_044711.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_044712.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_031698.1 Similar to Lactococcus lactis hypothetical ATP binding protein TR:Q9L650 (EMBL:AF242367) (207 aa) fasta scores: E(): 9.5e-26, 49.75% id in 207 aa, and to Streptococcus pneumoniae hypothetical protein TR:Q9ZHB1 (EMBL:AF068902) (213 aa) fasta scores: E(): 3.2e-24, 45.23% id in 210 aa YP_031700.1 Similar to Neisseria gonorrhoeae replication protein SW:REPA_NEIGO (P17492) (328 aa) fasta scores: E(): 6.7e-08, 22.09% id in 258 aa. Identical to Staphylococcus aureus plasmid pN315 replication protein Rep TR:Q9AC64 (EMBL:AP003139) (286 aa) fasta scores: E(): 6.4e-100, 100% id in 286 aa YP_031701.1 Similar to Lactococcus lactis transcriptional regulator LL0007 TR:Q9CJI6 (EMBL:AE006240) (107 aa) fasta scores: E(): 5e-09, 36.6% id in 112 aa. N-terminal region is highly similar to Staphylococcus aureus plasmid pN315 hypothetical protein SAP028 TR:Q9AC63 (EMBL:AP003139) (79 aa) fasta scores: E(): 1.4e-25, 98.73% id in 79 aa YP_031703.1 Poor database matches. Similar to Staphylococcus aureus plasmid pN315 hypothetical protein SAP029 TR:Q9AC61 (EMBL:AP003139) (61 aa) fasta scores: E(): 1.1e-25, 98.36% id in 61 aa YP_031704.1 Similar to Staphylococcus aureus plasmid pSK1 replication-associated protein Orf245 TR:Q9L8I7 (EMBL:AF203376) (245 aa) fasta scores: E(): 4e-18, 45.59% id in 261 aa, and to Staphylococcus haemolyticus plasmid pNVH97A hypothetical protein TR:Q9K4M8 (EMBL:AJ400722) (245 aa) fasta scores: E(): 1.5e-40, 63.56% id in 247 aa YP_031705.1 Almost identical to Staphylococcus aureus plasmid pRW001 putative cadmium resistance protein CadD TR:O05469 (EMBL:AF134905) (209 aa) fasta scores: E(): 2.9e-70, 99.04% id in 209 aa. Similar to Neisseria meningitidis cadmium resistance protein NMB1955 TR:Q9JXN6 (EMBL:AE002544) (208 aa) fasta scores: E(): 3.9e-41, 56.93% id in 209 aa YP_031706.1 Similar to Staphylococcus aureus plasmid pI258 cadmium efflux system accessory protein CadC SW:CADC_STAAU (P20047) (122 aa) fasta scores: E(): 7.8e-13, 42.45% id in 106 aa, and to Staphylococcus aureus plasmids pN315 and pC55s, putative regulator of cadB, CadX TR:Q9AC84 (EMBL:AP003139) (115 aa) fasta scores: E(): 1.1e-41, 99.13% id in 115 aa YP_031708.1 Similar to Staphylococcus aureus Tn552 transposable element potential ATP-binding protein SW:ATBP_STAAU (P18179) (271 aa) fasta scores: E(): 7.4e-99, 95.94% id in 271 aa, and to Listeria innocua plasmid pLI100 hypothetical protein Pli0057 TR:Q926K3 (EMBL:AL592102) (285 aa) fasta scores: E(): 2.8e-33, 51.97% id in 279 aa YP_031709.1 Similar to Staphylococcus aureus transposon Tn552 resolvase TnpR SW:BINL_STAAU (P18358) (197 aa) fasta scores: E(): 9.2e-71, 95.93% id in 197 aa, and to Staphylococcus epidermidis resolvase/integrase BinR TR:Q93SQ9 (EMBL:AY028779) (192 aa) fasta scores: E(): 6.9e-66, 90.62% id in 192 aa YP_031710.1 Highly similar to Staphylococcus aureus plasmid pI258 penicillinase repressor BlaI SW:BLAI_STAAU (P18415) (126 aa) fasta scores: E(): 3.4e-39, 99.2% id in 126 aa. Identical to Staphylococcus haemolyticus plasmids pNVH97A and pNVH96 beta-lactamase repressor BlaI TR:Q9K4N1 (EMBL:AJ400722) (126 aa) fasta scores: E(): 1e-39, 100% id in 126 aa YP_031711.1 Similar to Staphylococcus aureus Tn552 transposable element regulatory protein BlaR1 SW:BLAR_STAAU (P18357) (585 aa) fasta scores: E(): 7.1e-205, 94.01% id in 585 aa, and to Staphylococcus haemolyticus plasmid pNVH96 beta-lactamase inducer protein BlaR1 TR:Q9F2I0 (EMBL:AJ302698) (585 aa) fasta scores: E(): 7.9e-203, 92.99% id in 585 aa YP_031712.1 Similar to Staphylococcus aureus beta-lactamase precursor BlaZ SW:BLAC_STAAU (P00807) (281 aa) fasta scores: E(): 8.6e-94, 97.5% id in 281 aa, and to Enterococcus faecalis beta-lactamase BlaZ TR:AAA24777 (EMBL:M60253) (281 aa) fasta scores: E(): 8.6e-94, 97.5% id in 281 aa YP_031713.1 No significant database matches. Similar to Borrelia burgdorferi conserved hypothetical protein BBT02 TR:Q9S019 (EMBL:AE001583) (117 aa) fasta scores: E(): 1.7, 40.9% id in 44 aa YP_031714.1 Similar to Lactococcus lactis lactococcin 972 precursor LclA TR:O86283 (EMBL:AJ002203) (91 aa) fasta scores: E(): 0.021, 30.76% id in 78 aa. Identical to Staphylococcus aureus hypothetical protein SAP019 TR:Q9AC72 (EMBL:AP003139) (97 aa) fasta scores: E(): 4.5e-39, 100% id in 97 aa YP_031715.1 Similar to Lactococcus lactis hypothetical lactococcin 972 immunity protein LclB TR:Q9L651 (EMBL:AF242367) (648 aa) fasta scores: E(): 1.7e-13, 21.9% id in 662 aa. Almost identical to Staphylococcus aureus hypothetical protein SAP020 TR:Q9AC71 (EMBL:AP003139) (644 aa) fasta scores: E(): 0, 99.53% id in 644 aa YP_031716.1 Similar to Bacillus subtilis hypothetical protein yxea precursor YxeA or bsu39620 SWALL:YXEA_BACSU (SWALL:P54940) (115 aa) fasta scores: E(): 0.012, 30.69% id in 101 aa