-- dump date   	20140620_074503
-- class       	Genbank::CDS
-- table       	cds_note
-- id	note
NP_644816.1	binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.
NP_644817.1	binds the polymerase to DNA and acts as a sliding clamp
NP_644819.1	Required for DNA replication; binds preferentially to single-stranded, linear DNA
NP_644823.1	catalyzes the degradation of histidine to urocanate and ammmonia
NP_644824.1	catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_644827.1	hypothetical protein, similar to homoserine-o-acetyltransferase
NP_644830.1	in Escherichia coli this protein is wrapped around the base of the L1 stalk
NP_644832.1	catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis
NP_644838.1	hypothetical protein, similar to 5'-nucleotidase
NP_644839.1	SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA
NP_644844.1	glycerophosphoryldiester phosphodiesterase homologue
NP_644848.1	truncated hypothetical protein, similar to type I restriction-modification system endonuclease
NP_644849.1	hypothetical protein, similar to transposase
NP_644867.1	truncated hypothetical protein, similar to enterotoxin SEO
NP_644873.1	hypothetical protein, similar to homo sapiens CGI-44 protein, PRO1975 protein
NP_644877.1	hypothetical protein, similar to macrolide-efflux determinant
NP_644879.1	hypothetical protein, similar to transcriptional regulator (LysR family)
NP_644881.1	hypothetical protein, similar to transcriptional regulator
NP_644883.1	hypothetical protein, similar to DNA helicase
NP_644892.1	Uncharacterized HTH-type transcriptional regulator MW0077.
NP_644893.1	hypothetical protein, similar to aminoacylase
NP_644894.1	hypothetical protein, similar to transmembrane efflux pump protein
NP_644896.1	67 kDa Myosin-crossreactive streptococcal antigen homolog; in group A Streptococci this protein was found to cross react with anti myosin antibodies and may play a role in rheumatic fever
NP_644898.1	L-lactate permease homolog
NP_644900.1	staphylococcal accessory regulator A homologue
NP_644904.1	hypothetical protein, similar to cysteine synthase
NP_644905.1	hypothetical protein, similar to ornithine cyclodeaminase (EC 4.3.1.12)
NP_644907.1	hypothetical protein, similar to multi-drug resistance efflux pump
NP_644908.1	hypothetical protein, similar to rhizobactin siderophore biosynthesisprotein RhsC
NP_644909.1	hypothetical protein, similar to rhizobactin siderophore biosynthesisprotein RhsF
NP_644910.1	hypothetical protein, similar to various aldolase
NP_644911.1	hypothetical protein, similar to diaminopimelate decarboxylase (EC 4.1.1.20)
NP_644915.1	diacetyl
NP_644917.1	hypothetical protein, similar to UDP-glucose 4-epimerase (gale-1)
NP_644918.1	hypothetical protein, similar to glycosyltransferase TuaA
NP_644919.1	hypothetical protein, similar to Eps(Exopolysaccharide)G
NP_644920.1	hypothetical protein, similar to capsular polysaccharide synthesis protein 14H
NP_644921.1	hypothetical protein, similar to capsular polysaccharide synthesis protein 14L
NP_644924.1	hypothetical protein, similar to trehalose operon transcriptional repressor
NP_644925.1	catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate
NP_644926.1	hypothetical protein, similar to tetracyclin resistance protein
NP_644927.1	catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate
NP_644928.1	catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose
NP_644929.1	hypothetical protein, similar to phosphonates transport permease
NP_644930.1	hypothetical protein, similar to phosphonates transport permease
NP_644931.1	Phosphonates import ATP-binding protein phnC
NP_644932.1	hypothetical protein, similar to alkylphosphonate ABC tranporter
NP_644934.1	hypothetical protein, similar to lactococcal phosphatase homologue
NP_644937.1	truncated hypothetical protein, similar to transposase
NP_644955.1	iron regulated; catalyzes the release of heme from hemoglobin allowing bacterial pathogens to use the host heme as an iron source
NP_644957.1	aldehyde dehydrogenase homologue
NP_644958.1	hypothetical protein, similar to cation-efflux system membrane protein CzcD
NP_644960.1	hypothetical protein, similar to alpha-helical coiled-coil protein SrpF
NP_644961.1	hypothetical protein, similar to nitrate transporter
NP_644962.1	hypothetical protein, similar to membrane lipoprotein SrpL
NP_644963.1	hypothetical protein, similar to probable permease of ABC transporter
NP_644964.1	hypothetical protein, similar to acyl-CoA dehydrogenase family protein
NP_644966.1	Catalyzes the reversible two-electron oxidation of formate to carbon dioxide. It allows the assimilation of carbon dioxide and provides energy for growth through oxidative phosphorylation coupled to the reduction of oxygen, nitrate, sulphate or fumarate
NP_644967.1	hypothetical protein, similar to integral membrane protein LmrP
NP_644968.1	hypothetical protein, similar to surfactin synthetase
NP_644971.1	Acetylglutamate kinase
NP_644972.1	arginine biosynthesis bifunctional protein homologue; bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate
NP_644973.1	catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate
NP_644975.1	hypothetical protein, similar to branched-chain amino acid transport system carrier protein
NP_644976.1	hypothetical protein, similar to isochorismatase
NP_644977.1	hypothetical protein, similar to indole-3-pyruvate decarboxylas
NP_644978.1	PTS enzyme II (EC 2.7.1.69), glucose-specific, factor IIA homologue
NP_644980.1	catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway
NP_644981.1	PTS system EIIBC component MW0166 [Includes: Phosphotransferase enzyme IIB component
NP_644982.1	hypothetical protein, similar to transcription regulator
NP_644987.1	hypothetical protein, similar to ABC transporter ATP-binding protein
NP_644989.1	truncated hypothetical protein, similar to Enterococcus faecalis plasmid pPD1 bacI
NP_644993.1	hypothetical protein, similar to ABC transporter ATP-binding protein
NP_644997.1	truncated hypothetical protein, similar to oligopeptide ABC transporter permease
NP_644998.1	hypothetical protein, similar to dipeptide transporter protein dppC
NP_645000.1	hypothetical protein, similar to gamma-glutamyltranspeptidase precursor
NP_645002.1	NAD(P)H dehydrogenase homolog; FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds
NP_645003.1	hypothetical protein, similar to lysostaphin precursor
NP_645005.1	hypothetical protein, similar to maltose/maltodextrin-binding protein
NP_645006.1	maltose/maltodextrin transport permease homologue
NP_645007.1	maltose/maltodextrin transport permease homologue
NP_645008.1	hypothetical protein, similar to NADH-dependent dehydrogenase
NP_645009.1	hypothetical protein, similar to NADH-dependent dehydrogenase
NP_645012.1	cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate
NP_645013.1	Uncharacterized response regulatory protein MW0198.
NP_645014.1	Uncharacterized sensor-like histidine kinase MW0199
NP_645015.1	hypothetical protein, similar to periplasmic-iron-binding protein BitC
NP_645019.1	hypothetical protein, similar to glycerophosphodiester phosphodiesterase
NP_645022.1	acetyl-CoA acetyltransferase homologue
NP_645023.1	hypothetical protein, similar to 3-hydroxyacyl-CoA dehydrogenase
NP_645024.1	hypothetical protein, similar to glutaryl-CoA dehydrogenase
NP_645025.1	hypothetical protein, similar to acid-CoA ligase
NP_645028.1	hypothetical protein, similar to nickel ABC transporter nickel-binding protein
NP_645031.1	hypothetical protein, similar to flavohemoprotein
NP_645033.1	PTS enzyme (EC 2.7.1.69), maltose- and glucose-specific, factor II homologue
NP_645034.1	hypothetical protein, similar to inosine-uridine preferring nucleoside hydrolase
NP_645035.1	hypothetical protein, similar to BglG antiterminator family
NP_645036.1	hypothetical protein, similar to PTS fructose-specific enzyme IIBC component
NP_645037.1	hypothetical protein, similar to PTS, galactitol-specific IIB component
NP_645041.1	sorbitol dehydrogenase homologue
NP_645042.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers
NP_645043.1	hypothetical protein, similar to xylitol dehydrogenase
NP_645044.1	hypothetical protein, similar to teichoic acid biosynthesis protein B
NP_645045.1	hypothetical protein, similar to teichoic acid biosynthesis protein F
NP_645046.1	4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers
NP_645047.1	hypotheticl protein, similar to D-xylulose reductase
NP_645048.1	hypothetical protein, similar to teichoic acid biosynthesis protein B
NP_645049.1	hypothetical protein, similar to beta-glycosyltransferase
NP_645050.1	involved in peptidoglycan cross-linking
NP_645053.1	negatively regulates murein hydrolase activity
NP_645054.1	in conjunction with LrgA this protein inhibits the expression or activity of extracellular murein hydrolases
NP_645055.1	hypothetical protein, similar to transcription regulator GntR family
NP_645056.1	hypothetical protein, similar to PTS beta-glucoside-specific enzyme II, ABC component
NP_645060.1	cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source
NP_645061.1	Putative ribose uptake protein rbsU.
NP_645062.1	hypothetical protein, similar to rbs operon repressor RbsR
NP_645065.1	hypothetical protein, similar to proton antiporter efflux pump
NP_645066.1	hypothetical protein, similar to penicillin amidase (EC 3.5.1.11) V
NP_645072.1	hypothetical protein, similar to secretory antigen precursor SsaA
NP_645074.1	Protein esaA.
NP_645079.1	Protein essC.
NP_645099.1	hypothetical protein, similar to formate transporter NirC
NP_645100.1	hypothetical protein, similar to branched-chain amino acid uptake carrier
NP_645101.1	hypothetical protein, similar to outer membrane protein precursor
NP_645103.1	hypothetical protein, similar to ABC transporter ATP-binding protein
NP_645104.1	hypothetical protein, similar to regulatory protein PfoR
NP_645108.1	hypothetical protein, similar to sodium-coupled permease
NP_645109.1	catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid
NP_645110.1	hypothetical protein, similar to glucokinase
NP_645112.1	Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate
NP_645116.1	hypothetical protein, similar to trimethylamine dehydrogenase (EC 1.5.99.7)
NP_645117.1	hypothetical protein, similar to alkanal monooxygenase alpha chain
NP_645118.2	hypothetical protein, similar to glycine cleavage system H protein
NP_645121.1	hypothetical protein, similar to lipoate-protein ligase
NP_645122.1	hypothetical protein, similar to dihydroflavonol-4-reductase
NP_645123.1	hypothetical protein, similar to transport protein SgaT; membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr
NP_645125.1	hypothetical protein, similar to PTS fructose-specific enzyme IIBC component
NP_645126.1	hypothetical protein, similar to transcription antiterminator BglG family
NP_645127.1	hypothetical protein, similar to transcription regulator
NP_645133.1	hypothetical protein, similar to NADH-dependent FMN reductase
NP_645135.1	hypothetical protein, similar to ribosomal-protein-serine N-acetyltransferase
NP_645142.1	hypothetical protein, similar to transcriptional repressor
NP_645144.1	hypothetical protein, similar to ABC transporter ATP-binding protein
NP_645146.1	hypothetical protein, similar to low temperature requirement A protein
NP_645147.1	acetyl-CoA C-acetyltransferase homologue
NP_645149.1	catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine
NP_645150.1	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions
NP_645151.1	hypothetical protein, similar to cystathionine beta-lyase
NP_645152.1	hypothetical protein, similar to cystathionine gamma-synthase
NP_645153.1	hypothetical protein, similar to transcription terminator
NP_645156.1	hypothetical protein, similar to GTP-binding protein; translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1
NP_645158.1	binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21
NP_645160.1	binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit
NP_645161.1	hypothetical protein, similar to hypothetical protein virulence plasmid pXO1-38
NP_645162.1	hypothetical protein, similar to exotoxin 2
NP_645168.1	truncated hypothetical protein, similar to phosphoglycerate mutase; Gpm3p
NP_645175.1	NADPH-dependent oxidoreductase
NP_645176.1	hypothetical protein, similar to proton/sodium-glutamate symport protein
NP_645181.1	Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine
NP_645184.1	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
NP_645185.1	hypothetical protein, similar to AbiD1 [Genomic island nu Sa alpha2]
NP_645199.1	exotoxin homolog; these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation
NP_645200.1	exotoxin homolog]; these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation
NP_645201.1	exotoxin homolog; these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation
NP_645202.1	exotoxin homolog; these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation
NP_645203.1	exotoxin homolog; SSL5, SET3, SET10; bind P-selectin glycoprotein ligand-1 and inhibit P-selectin-mediated neutrophil rolling along the endothelium; these proteins share structural homology to known superantigens but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation
NP_645204.1	exotoxin homolog; these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation
NP_645205.1	exotoxin homolog; SSL7, SET1; blocks IgA-FcR interactions and inhibits complement, leading to increased survival of a sensitive bacterium in blood
NP_645206.1	exotoxin homolog; these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation
NP_645207.1	exotoxin homolog; these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation
NP_645208.1	exotoxin homolog; these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation
NP_645211.1	exotoxin homolog; these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation
NP_645224.1	Catalyzes the transfer of electrons from NADH to ubiquinone
NP_645228.1	hypothetical protein, similar to carboxylesterase
NP_645230.1	hypothetical protein, similar to sodium-dependent transporter
NP_645231.1	cysteine synthase homologue
NP_645233.1	Methionine import ATP-binding protein metN 1
NP_645234.1	hypothetical protein, similar to ABC transporter permease protein
NP_645235.1	hypothetical protein, similar to lactococcal lipoprotein
NP_645236.1	N-acetylmuramoyl-L-alanine amidase sle1 precursor
NP_645244.1	glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate
NP_645245.1	phosphoenolpyruvate-dependent, trehalose-specific
NP_645247.1	hypothetical protein, similar to trehalose operon transcriptional repressor
NP_645252.1	involved in a recombinational process of DNA repair, independent of the recBC complex
NP_645253.1	hypothetical protein, similar to lysine decarboxylase
NP_645254.1	thymidylate kinase homologue; catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP)
NP_645257.1	hypothetical protein, similar to signal peptidase II homologue
NP_645258.1	in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA
NP_645262.1	methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content
NP_645265.1	dimethyladenosine transferase(16S rRNA dimethylase) homologue; catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin
NP_645266.1	VEG protein homologue
NP_645267.1	An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis
NP_645268.1	pur operon repressor homologue
NP_645269.1	translation initiation inhibitor homologue
NP_645270.1	stage V sporulation protein G homologue; stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus
NP_645271.1	UDP-N-acetylglucosamine pyrophosphorylase homologue; forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis
NP_645272.1	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP
NP_645273.1	the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response
NP_645274.1	Enables the recycling of peptidyl-tRNAs produced at termination of translation
NP_645276.1	hypothetical protein, similar to low temperature requirement B protein
NP_645279.1	hypothetical protein, similar to cell-division initiation protein
NP_645280.1	hypothetical protein, similar to polyribonucleotide nucleotidyltransferase
NP_645282.1	hypoxanthine-guanine phosphoribosyltransferase homologue
NP_645284.1	heat-shock protein HSP33 homologue; becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers
NP_645285.1	cysteine synthase (o-acetylserine sulfhydrylase) homologue
NP_645289.1	class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1
NP_645290.1	hypothetical protein, similar to transcription regulator GntR family
NP_645291.1	with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate
NP_645292.1	with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate
NP_645294.1	transcription repressor of class III stress genes homologue
NP_645298.1	DNA repair protein homologue; Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents
NP_645300.1	Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation
NP_645301.1	Serine acetyltransferase homologue
NP_645302.1	catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA
NP_645304.1	Putative trmH family tRNA/rRNA methyltransferase
NP_645307.1	forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force
NP_645309.1	binds directly to 23S ribosomal RNA
NP_645310.1	in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA
NP_645311.1	binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit
NP_645312.1	present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors
NP_645314.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme
NP_645315.1	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter
NP_645316.1	Putative ribosomal protein L7Ae-like; in Bacillus subtilis this non-essential protein associates with the ribosome
NP_645317.1	interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance
NP_645318.1	binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit
NP_645319.1	EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene
NP_645320.1	EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu
NP_645321.1	hypothetical protein, similar to N-acyl-L-amino acid amidohydrolase
NP_645322.1	catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine
NP_645323.1	Hsp31 stabilizes early unfolding protein intermediates under severe heat stress
NP_645324.1	catalyzes the phosphorylation of ribulose to ribulose 5-phosphate
NP_645325.1	Uncharacterized epimerase/dehydratase MW0508.
NP_645326.1	branched-chain amino acid aminotroansferase homologue; catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids
NP_645328.1	hypothetical protein, similar to deoxypurine kinase
NP_645329.1	hypothetical protein, similar to deoxypurine kinase
NP_645330.1	hypothetical protein, similar to Cu binding protein (Mn oxidation)
NP_645336.1	hypothetical protein, similar to poly (glycerol-phosphate) alpha-glucosyltransferase (teichoic acid biosynthesis)
NP_645337.1	hypothetical protein, similar to poly (glycerol-phosphate) alpha-glucosyltransferase (teichoic acid biosynthesis)
NP_645338.1	similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis
NP_645342.1	3-hexulose-6-phosphate synthase
NP_645344.1	hypothetical protein, similar to indigoidine systhesis protein
NP_645345.1	proline/betaine transporter homologue
NP_645347.1	similar to long chain fatty acid CoA ligase
NP_645352.1	hypothetical protein, similar to phosphomethylpyrimidine kinase, thiD homologue
NP_645353.1	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NP_645356.1	hypothetical protein, similar to cationic amino acid transporter
NP_645360.1	in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta
NP_645366.1	mercuric reductase homologue
NP_645380.1	hypothetical protein, similar to oxidoreductase, ion channel
NP_645385.1	similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs
NP_645388.1	catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase
NP_645389.1	hypothetical protein, similar to endonuclease III
NP_645390.1	hypothetical protein, similar to iron-binding protein
NP_645391.1	hypothetical protein, similar to iron(III) ABC transporter permease protein
NP_645392.1	hypothetical protein, similar to L-2-haloalkanoic acid dehalogenase
NP_645393.1	hypothetical protein similar to 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolase
NP_645396.1	hypothetical protein, similar to esterase/lipase
NP_645401.1	hypothetical protein, similar to FimE recombinase
NP_645402.1	Hypothetical protein, similar to NADH dehydrogenase; subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
NP_645403.1	hypothetical protein, similar to Na+/H+ antiporter; subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
NP_645404.1	hypothetical protein, similar to Na+/H+ antiporter; subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
NP_645405.1	MnhD homologue, similar to Na+/H+ antiporter subunit; subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; in S. meliloti it is known to be involved specifically with K+ transport
NP_645406.1	hypothetical protein, similar to Na+/H+ antiporter; subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport
NP_645407.1	hypothetical protein, similar to Na+/H+ antiporter; subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
NP_645408.1	subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
NP_645410.1	lipoprotein, Streptococcal adhesin PsaA homologue
NP_645412.1	hypothetical protein, similar to ABC transporter ATP-binding protein
NP_645413.1	hypothetical protein, similar to iron dependent repressor
NP_645416.1	with TagG is involved in the export of teichoic acids
NP_645424.1	hypothetical protein, similar to pyrimidine nucleoside transporter
NP_645429.1	hypothetical protein, similar to dihydroxyacetone kinase; with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase
NP_645434.1	hypothetical protein, similar to lipase LipA
NP_645438.1	hypothetical protein, similar to two-component response regulator
NP_645439.1	hypothetical protein, similar to two-component sensor histidine kinase
NP_645443.1	hypothetical protein, similar to low-affinity inorganic phosphate transporter
NP_645444.1	secretory antigen SsaA homologue
NP_645446.1	hypothetical protein, similar to AraC/XylS family transcriptional regulator
NP_645451.1	hypothetical protein, similar to LysR family transcriptional regulator
NP_645452.1	hypothetical protein, similar to sugar efflux transpoter
NP_645462.1	BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell
NP_645463.1	similar to ABC transporter required for expression of cytochrome bd
NP_645464.1	similar to ABC transporter required for expression of cytochrome bd
NP_645465.1	similar to transcriptional regulator
NP_645466.1	similar to cobalamin synthesis related protein
NP_645467.1	similar to aryl-alcohol dehydrogenase
NP_645470.1	similar to deoxyribodipyrimidine photolyase
NP_645476.1	hypothetical protein, similar to transcription regulation protein
NP_645477.1	hypothetical protein, similar to transcription repressor of fructose operon
NP_645481.1	hypothetical protein, similar to hemolysin homologue
NP_645482.1	hypothetical protein, similar to plant-metabolite dehydrogenases
NP_645483.1	hypothetical protein, similar to CsbB stress response protein
NP_645489.1	coenzyme PQQ synthesis homologue
NP_645490.1	6-pyruvoyl tetrahydrobiopterin synthase homolog
NP_645492.1	hypothetical protein, similar to anthranilate synthase component II
NP_645493.1	hypothetical protein, similar to para-aminobenzoate synthase component I
NP_645494.1	hypothetical protein, similar to para-aminobenzoate synthase component I
NP_645496.1	hypothetical protein, similar to urea amidolyase
NP_645498.1	Glycerol phosphate lipoteichoic acid synthase
NP_645499.1	hypothetical protein, similar to ABC transporter ATP-binding protein
NP_645501.1	hypothetical protein, similar to choline transport ATP-binding protein
NP_645502.1	hypothetical protein, similar to choline transporter
NP_645503.1	Histidinol-phosphate aminotransferase; catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis
NP_645505.1	hypothetical protein, similar to multidrug resistance protein
NP_645506.1	hypothetical protein, similar to di-tripepride ABC transporter
NP_645507.1	NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis
NP_645509.1	in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF
NP_645510.1	Catalyzes the rate-limiting step in dNTP synthesis
NP_645511.1	B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE
NP_645512.1	hypothetical protein, similar to ferrichrome ABC transporter permease
NP_645513.1	hypothetical protein, similar to ferrichrome ABC transporter permease
NP_645514.1	hypothetical protein, similar to ferrichrome ABC transporter ATP-binding protein
NP_645515.1	lipoprotein, similar to ferrichrome ABC transporter
NP_645517.1	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis
NP_645521.1	hypothetical protein, similar to glycerate kinase
NP_645522.1	catalyzes the release of the N-terminal amino acid from a tripeptide
NP_645529.1	hypothetical protein, similar to comF operon protein 1
NP_645530.1	hypothetical protein, similar to comF operon protein 3
NP_645532.1	functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins
NP_645537.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion
NP_645538.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NP_645539.1	catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system
NP_645540.1	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein
NP_645541.1	Putative acetyltransferase MW0724
NP_645547.1	ATP-dependent Clp protease proteolyticsubunit homologue; hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates
NP_645548.1	similar to cell-division inhibitor
NP_645552.1	Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway
NP_645553.1	Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate
NP_645554.1	catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NP_645555.1	enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis
NP_645558.1	carboxyesterase precursor homologue
NP_645560.1	binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation
NP_645562.1	similar to integrase [Genomic island nu Sa alpha3mw]
NP_645585.1	hypothetical protein, similar to extracellular matrix and plasma binding
NP_645595.1	hypothetical protein, similar to phosphoglycerate mutase
NP_645597.1	hypothetical protein, similar to lactococcal prophage ps3 protein 05
NP_645598.1	Organic hydroperoxide resistance protein-like.
NP_645599.1	catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis
NP_645601.1	hypothetical protein, similar to thioredoxin
NP_645602.1	hypothetical protein, similar to arsenate reductase
NP_645603.1	glycine cleavage system protein H homologue; part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor
NP_645606.1	hypothetical protein, similar to thioredoxin
NP_645607.1	ABC transporter ATP-binding protein homolog
NP_645612.1	ABC transporter ATP-binding protein homologue
NP_645614.1	aminotransferase NifS homologue
NP_645615.1	hypothetical protein, similar to nitrogen fixation protein NifU
NP_645619.1	hypothetical protein, similar to hemolysin
NP_645620.1	hypothetical protein, similar to 2-nitropropane dioxygenase
NP_645624.1	catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group
NP_645628.1	Protein nagD homolog.
NP_645629.1	hypothetical protein, similar to glycerate dehydrogenase
NP_645631.1	transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid
NP_645633.1	D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid
NP_645635.1	similar to nitrogen fixation protein NifU
NP_645637.1	hypothetical protein, similar to NADH dehydrogenase
NP_645640.1	NADH dehydrogenase-like protein MW0823
NP_645645.1	subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
NP_645646.1	subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
NP_645647.1	subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
NP_645648.1	subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone
NP_645649.1	subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
NP_645650.1	subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in the case of S. meliloti it was proved to be involved specifically with K+ transport
NP_645651.1	subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali
NP_645653.1	peptidyl-prolyl cis-trans isomerase homologue
NP_645654.1	hypothetical protein, similar to polyribonucleotide nucleotidyltransferase
NP_645655.1	hypothetical protein, similar to NADH-dependent flavin oxidoreductase
NP_645659.1	catalyzes the formation of arginine from (N-L-arginino)succinate
NP_645660.1	catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming
NP_645661.1	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family
NP_645665.1	hypothetical protein, similar to ATP-dependent nuclease subunit
NP_645666.1	hypothetical protein, similar to ATP-dependent nuclease subunit A
NP_645667.1	hypothetical protein, similar to 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxylase
NP_645669.1	NADPH-dependent; catalyzes the reduction of coenzyme A disulfide
NP_645673.1	Putative O-acetyltransferase MW0856
NP_645674.1	ClpB chaperone homologue
NP_645675.1	hypothetical protein, similar to transcription regulator LysR family
NP_645676.1	hypothetical protein, similar to 2-isopropylmalate synthase
NP_645680.1	hypothetical protein, similar to cell surface protein Map-w
NP_645682.1	3-oxoacyl-(acyl-carrier protein) synthase homologue; FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs
NP_645686.1	hypothetical protein, similar to oligopeptide transport system permease protein OppC
NP_645687.1	oligopeptide transport system ATP-binding protein OppD homologue
NP_645688.1	oligopeptide transport system ATP-binding protein OppF homologue
NP_645689.1	hypothetical protein, similar to peptide binding protein OppA
NP_645690.1	hypothetical protein, similar to oligopeptide ABC transporter oligopeptide-binding protein
NP_645691.1	oligopeptide ABC transporter ATP-binding protein homologue
NP_645692.1	oligopeptide transport system ATP-binding protein AppF homologue
NP_645694.1	Hypothetical protein, similar to oligopeptide transport system permease protein OppC
NP_645695.1	catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_645696.1	the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress
NP_645697.1	Adapter protein mecA; enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence
NP_645698.1	hypothetical protein, similar to transcription factor
NP_645699.1	thimet oligopeptidase homologue
NP_645705.1	catalyzes the phosphorylation of NAD to NADP
NP_645707.1	hypothetical protein, similar to Mg2+ transporter
NP_645708.1	Na+/H+ antiporter homologue
NP_645709.1	Catalyzes a key regulatory step in fatty acid biosynthesis
NP_645711.1	hypothetical protein, similar to Na+/H+-dependent alanine carrier protein
NP_645713.1	similar to 2'-5' RNA ligase
NP_645714.1	Probable glycolipid permease ltaA (Lipoteichoic acid protein A).
NP_645715.1	Processive diacylglycerol glucosyltransferase; processive; catalyzes the formation of mono-, di- and tri-glucosyldiacylglycerol by the progressive transfer of glucosyl residues to diacylglycerol; involved in the formation of membrane glycolipids
NP_645716.1	involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine
NP_645718.1	stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein
NP_645719.1	toxic anion resistance protein homologue
NP_645721.1	hypothetical protein, similar to Na+-transporting ATP synthase
NP_645722.1	hypothetical protein, similar to nucleotidase
NP_645723.1	hypothetical protein, similar to competence transcription factor
NP_645725.1	lipoate-protein ligase homolog
NP_645729.1	hypothetical protein, similar to lactococcin 972
NP_645731.1	truncated hypothetical protein, similar to lactococcin 972 immunity factor
NP_645736.1	hypothetical protein, similar to UDP-glucose:polyglycerol phosphate glucosyltransferase
NP_645738.1	hypothetical protein, similar to ferrichrome ABC transporter
NP_645742.1	hypothetical protein, similar to 1,4-dihydroxy-2-naphthodate octaprenyltransferase; catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate
NP_645743.1	hypothetical protein, similar to menaquinone-specific isochorismate synthase
NP_645746.1	catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA
NP_645750.1	HisC homolog
NP_645752.1	hypothetical protein, probable ATL autolysin transcription regulator
NP_645758.1	Probable quinol oxidase subunit 4
NP_645761.1	Probable quinol oxidase subunit 2 precursor
NP_645762.1	hypothetical protein, similar to chitinase B
NP_645763.1	catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate
NP_645764.1	hypothetical protein, similar to phosphoribosylaminoimidazole carboxylase PurE
NP_645765.1	phosphoribosylaminoimidazole carboxylase carbon dioxide-fixation chain PurK homolog; With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway
NP_645766.1	phosphoribosylaminoimidazolesuccinocarboxamide synthetase homolog; catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase
NP_645768.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
NP_645769.1	catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis
NP_645770.1	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway
NP_645771.1	catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis
NP_645773.1	involved in de novo purine biosynthesis
NP_645774.1	catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis
NP_645776.1	hypothetical protein, similar to cation ABC transporter
NP_645785.1	cytochrome D ubiquinol oxidase subunit 1 homolog
NP_645786.1	cytochrome D ubiquinol oxidase subunit II homolog
NP_645791.1	formylmethionine deformylase homolog; cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
NP_645796.1	E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide
NP_645799.1	spermidine/putrescine ABC transporter, ATP-binding protein homolog
NP_645800.1	spermidine/putrescine ABC transporter homolog
NP_645801.1	spermidine/putrescine ABC transporter homolog
NP_645802.1	spermidine/putrescine-binding protein precursor homolog
NP_645805.1	Probable manganese transport protein mntH.
NP_645807.1	myo-inositol-1(or 4)-monophosphatase homolog
NP_645809.1	GTP-binding elongation factor homolog
NP_645812.1	depletion of this protein in Bacillus subtilis results in defects in cell morphology; crystal structure of Staphylococcus protein shows homodimer; putative ligand binding protein
NP_645814.1	biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate
NP_645815.1	hypothetical protein, similar to heme synthase
NP_645816.1	cytochrome caa3 oxidase (assembly factor) homolog; converts protoheme IX and farnesyl diphosphate to heme O
NP_645820.1	hypothetical protein, similar to glycerophosphoryl diester phosphodiesterase
NP_645824.1	phosphopantetheine adenyltransferase homolog; Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA
NP_645827.1	some L32 proteins have zinc finger motifs consisting of CXXC while others do not
NP_645832.1	hypothetical protein, similar to ferrichrome ABC transporter
NP_645833.1	hypothetical protein, similar to ferrichrome ABC transporter
NP_645835.1	iron regulated; catalyzes the release of heme from hemoglobin allowing bacterial pathogens to use the host heme as an iron source
NP_645837.1	hypothetical protein, similar to rRNA methylase
NP_645838.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily
NP_645839.1	catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily
NP_645840.1	Ribonuclease HIII; An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
NP_645844.1	MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange
NP_645846.1	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NP_645848.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol
NP_645849.1	part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase
NP_645850.1	converts L-glutamate to D-glutamate, a component of peptidoglycan
NP_645851.1	hydrolyzes non-standard nucleotides such as xanthine and inosine
NP_645855.1	FLIPr; secreted protein that blocks the formyl peptide receptor-like 1 (FPRL1) found in neutrophils, monocytes, B cells, and NK cells; inhibits the binding of chemoattractants (such as formylated peptides) to FPRL1, which initiates the phagocyte mobilization towards the infection site
NP_645858.1	hypothetical protein, similar to fibrinogen-binding protein
NP_645864.1	hypothetical protein, similar to exotoxin 1; these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation
NP_645865.1	hypothetical protein, similar to exotoxin 4; these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation
NP_645866.1	hypothetical protein, similar to exotoxin 3; these proteins share structural homology to known superantigen proteins but do not exhibit any of the properties expected such as histocompatibility complex class II binding or broad T-cell activation
NP_645867.1	catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation
NP_645868.1	Carbamate kinase 1; catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP
NP_645873.1	hypothetical protein, similar to antibacterial protein
NP_645874.1	hypothetical protein, similar to antibacterial protein
NP_645878.1	MraZ; UPF0040; crystal structure shows similarity to AbrB
NP_645882.1	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NP_645883.1	UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation
NP_645884.1	cell division protein, FtsQ homolog
NP_645886.1	GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function
NP_645891.1	hypothetical protein, similar to cell-division protein
NP_645892.1	hypothetical protein, similar to cell-divisio initiation protein
NP_645893.1	IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme
NP_645896.1	lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis
NP_645898.1	regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity
NP_645900.1	catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis
NP_645901.1	catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis
NP_645902.1	catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers
NP_645903.1	four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity
NP_645904.1	type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase
NP_645905.1	involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate
NP_645908.1	hypothetical protein, similar to fibrinogen binding protein
NP_645909.1	guanylate kinase homolog; Essential for recycling GMP and indirectly, cGMP
NP_645910.1	Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NP_645911.1	pantothenate metabolism flavoprotein homolog
NP_645915.1	Peptide deformylase-like (Polypeptide deformylase-like); cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+)
NP_645917.1	hypothetical protein, similar to RNA-binding Sun protein
NP_645918.1	23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance
NP_645920.1	hypothetical protein, similar to protein kinase
NP_645922.1	ribulose-5-phosphate 3-epimerase homolog
NP_645924.1	required for 70S ribosome assembly
NP_645927.1	catalyzes branch migration in Holliday junction intermediates
NP_645928.1	negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria
NP_645929.1	involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY
NP_645932.1	carries the fatty acid chain in fatty acid biosynthesis
NP_645933.1	cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity
NP_645937.1	signal recognition particle homolog
NP_645938.1	binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity
NP_645939.1	Essential for efficient processing of 16S rRNA
NP_645940.1	methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA
NP_645941.1	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NP_645943.1	essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc)
NP_645944.1	RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids
NP_645945.1	catalyzes the interconversion of succinyl-CoA and succinate
NP_645946.1	Catalyzes the only substrate-level phosphorylation in the TCA cycle
NP_645949.1	hypothetical protein, similar to DNA processing Smf protein
NP_645950.1	probable phosphoesterase; catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity
NP_645951.1	TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine
NP_645952.1	site-specific recombinase XerC homolog
NP_645953.1	heat shock protein involved in degradation of misfolded proteins
NP_645954.1	heat shock protein involved in degradation of misfolded proteins
NP_645955.1	CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NP_645956.1	one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit
NP_645957.1	EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu
NP_645958.1	Catalyzes the phosphorylation of UMP to UDP
NP_645959.1	Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs
NP_645960.1	catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate
NP_645963.1	catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro)
NP_645964.1	catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity
NP_645965.1	in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins
NP_645966.1	modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination
NP_645968.1	hypothetical protein, similar to ribosomal protein L7AE family
NP_645969.1	Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NP_645970.1	associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock
NP_645971.1	catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs
NP_645973.1	primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence
NP_645976.1	DNA translocase ftsK.
NP_645977.1	hypothetical protein, similar to transcription regulator GntR family
NP_645978.1	hypothetical protein, similar to processing proteinase homolog
NP_645979.1	hypothetical protein, similar to precessing proteinase
NP_645980.1	hypothetical protein, similar to 3-oxoacyl- acyl-carrier protein reductase homolog ymfI
NP_645985.1	catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
NP_645986.1	protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP
NP_645989.1	hypothetical protein, similar to 2-oxoacid ferredoxin oxidoreductase, alpha subunit
NP_645990.1	hypothetical protein, similar to 2-oxoacid ferredoxin oxidoreductase, beta subunit; catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin
NP_645992.1	catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A)
NP_645995.1	This protein performs the mismatch recognition step during the DNA repair process
NP_645996.1	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NP_646000.1	Converts glycerol and ADP to glycerol-3-phosphate and ADP
NP_646002.1	hypothetical protein, similar to lysophospholipase
NP_646003.1	IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity
NP_646004.1	hypothetical protein, similar to host factor-1
NP_646006.1	hypothetical protein, similar to GTP-binding protein proteinase modulator homolog ynbA
NP_646007.1	hypothetical protein, similar to aluminum resistance protein
NP_646022.1	cardiolipin synthetase homolog
NP_646023.1	ABC transporter (ATP-binding protein) homolog
NP_646024.1	hypothetical protein, similar to ABC transporter integral membrane protein
NP_646025.1	hypothetical protein, similar to two-component sensor histidine kinase
NP_646026.1	hypothetical protein, similar to two-component response regulator
NP_646031.1	aspartate kinase homolog; catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive
NP_646032.1	catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine
NP_646033.1	catalyzes the formation of L-threonine from O-phospho-L-homoserine
NP_646034.1	homoserine kinase homolog; catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate
NP_646039.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
NP_646040.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif
NP_646041.1	GMP reductase
NP_646043.1	Represses a number of genes involved in the response to DNA damage
NP_646049.1	hypothetical protein, similar to exonuclease SbcD
NP_646050.1	hypothetical protein, similar to exonuclease SbcC
NP_646052.1	forms homopentamer; channel that opens in response to pressure or hypoosmotic shock
NP_646054.1	Catalyzes the conversion of citrate to isocitrate
NP_646058.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
NP_646059.1	decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling
NP_646065.1	peptide methionine sulfoxide reductase homolog; this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress
NP_646068.1	hypothetical protein, similar to DNA-damage repair protein
NP_646069.1	catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate
NP_646070.1	hypothetical protein, similar to glucanase
NP_646071.1	hypothetical protein, similar to anthranilate synthase component I; with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine
NP_646073.1	Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate
NP_646074.1	involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water
NP_646075.1	catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis
NP_646076.1	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate
NP_646077.1	catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis
NP_646089.1	hypothetical protein, similar to oligoendopeptidase
NP_646090.1	hypothetical protein, similar to negative regulator PhoU
NP_646091.1	ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation
NP_646092.1	hypothetical protein, similar to phosphate ABC transporter
NP_646093.1	hypothetical protein, similar to phosphate ABC transporter
NP_646097.1	ABC transporter (ATP-binding protein) homolog
NP_646098.1	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.
NP_646100.1	catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis
NP_646101.1	catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis
NP_646104.1	hypothetical protein, similar to alanine racemase
NP_646109.1	catalyzes the hydrolysis of acylphosphate
NP_646110.1	hypothetical protein, similar to 5-bromo-4-chloroindolyl phosphate hydrolysis protein xpaC
NP_646111.1	TelA-like protein MW1294.
NP_646116.1	hypothetical protein, similar to nitric-oxide reductase
NP_646118.1	ABC transporter homolog
NP_646119.1	component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA
NP_646120.1	SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide
NP_646124.1	UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis
NP_646130.1	this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress
NP_646131.1	this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress
NP_646134.1	ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived
NP_646140.1	hypothetical protein, similar to cell wall enzyme EbsB
NP_646141.1	hypothetical protein, similar to streptococcal adhesin emb
NP_646143.1	hypothetical protein, similar to amino acid pearmease
NP_646144.1	threonine deaminase IlvA homolog; catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic
NP_646146.1	hypothetical protein, similar to 5'-3' exonuclease
NP_646156.1	recombination protein U homolog; functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC
NP_646160.1	hypothetical protein, similar to chromosome replication initiation protein dnaD
NP_646161.1	catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_646164.1	CCA-adding enzyme; catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity
NP_646165.1	hypothetical protein, similar to lipopolysaccharide biosynthesis-related pr homolog
NP_646171.1	(5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS); catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
NP_646172.1	catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis
NP_646173.1	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis
NP_646175.1	catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate
NP_646177.1	Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone
NP_646178.1	hypothetical protein, similar to component A of hexaprenyl diphosphate synthase
NP_646180.1	catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate
NP_646181.1	GTP-binding protein engA; EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains
NP_646182.1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins
NP_646183.1	Catalyzes the formation of (d)CDP from ATP and (d)CMP
NP_646185.1	hypothetical protein, similar to thioredoxin reductase homolog
NP_646228.1	hypothetical protein, similar to int gene activator RinB [Bacteriophage phi Sa 2mw]
NP_646252.1	hypothetical protein, similar to Cro-like protein from Streptococcus pyogenes M1 GAS [Bacteriophage phi Sa 2mw]
NP_646260.1	[bacteriophage]
NP_646269.1	ferric uptake regulator homolog
NP_646273.1	hypothetical protein, similar to oxidoreductase
NP_646274.1	Pyrroline-5-carboxylate reductase
NP_646276.1	catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
NP_646277.1	transcription regulator AraC/XylS family homolog
NP_646281.1	catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate
NP_646282.1	hypothetical protein, similar to tripeptidase
NP_646290.1	regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes
NP_646291.1	geranyltranstransferase homolog
NP_646292.1	Exodeoxyribonuclease 7 small subunit; catalyzes the bidirectional exonucleolytic cleavage of DNA
NP_646293.1	Exodeoxyribonuclease 7 large subunit; bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides
NP_646294.1	N utilization substance protein B homolog (Protein nusB); Regulates rRNA biosynthesis by transcriptional antitermination
NP_646296.1	an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NP_646298.1	Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA
NP_646304.1	glycine dehydrogenase (decarboxylating) subunit 2 homolog; acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein
NP_646305.1	acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein
NP_646306.1	catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein
NP_646307.1	Shikimate kinase
NP_646308.1	hypothetical protein, similar to ComYC protein
NP_646310.1	hypothetical protein, similar to competence protein
NP_646312.1	hypothetical protein, similar to DNA transport machinery protein comGB
NP_646313.1	hypothetical protein, similar to late competence protein comGA
NP_646320.1	in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif
NP_646323.1	ferric uptake regulator homolog
NP_646324.1	hypothetical protein, similar to ABC transporter
NP_646325.1	hypothetical protein, similar to ABC transporter ATP-binding protein
NP_646326.1	Probable endonuclease 4; Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues
NP_646327.1	hypothetical protein, similar to ATP-dependent RNA helicase
NP_646330.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium
NP_646334.1	Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_646335.1	DNA repair protein recO (Recombination protein O).
NP_646336.1	GTP-binding protain Era homolog; Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome
NP_646338.1	hypothetical protein, similar to diacylglycerol kinase
NP_646340.1	phosphate starvation-induced protein phoH homolog
NP_646344.1	a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA
NP_646346.1	in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase
NP_646347.1	methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype
NP_646348.1	chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion
NP_646349.1	heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria
NP_646350.1	with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor
NP_646352.1	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III
NP_646353.1	binds to the ribosome on the universally-conserved alpha-sarcin loop
NP_646354.1	binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase
NP_646355.1	required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA
NP_646356.1	hypothetical protein, similar to ComEC late competence protein 3 (comE operon)
NP_646358.1	hypothetical protein, similar to late competence operon required for DNA binding and uptake comEA
NP_646365.1	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NP_646369.1	enterotoxin homolog
NP_646373.1	acetyl-CoA carboxylase (biotin carboxylase subunit), accC homolog
NP_646374.1	hypothetical protein, similar to acetyl-CoA carboxylase (biotin carboxyl carrier subunit), accB homolog
NP_646377.1	necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NP_646378.1	functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor
NP_646379.1	hypothetical protein, similar to protease
NP_646380.1	hypothetical protein, similar to protease
NP_646381.1	hypothetical protein, similar to caffeoyl-CoA O-methyltransferase
NP_646383.1	similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function
NP_646385.1	Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NP_646386.1	hypothetical protein, similar to deoxyribonuclease
NP_646388.1	catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs
NP_646389.1	iron-sulfur cofactor synthesis protein homolog
NP_646397.1	catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes
NP_646398.1	catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG
NP_646400.1	hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine
NP_646402.1	catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis
NP_646403.1	hypothetical protein, similar to single-strand DNA-specific exonuclease
NP_646404.1	part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF
NP_646406.1	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)
NP_646407.1	Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step
NP_646408.1	promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration
NP_646409.1	plays an essential role in ATP-dependent branch migration of the Holliday junction
NP_646410.1	ACT domain-containing protein pheB.
NP_646411.1	essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication
NP_646412.1	involved in the peptidyltransferase reaction during translation
NP_646415.1	hypothetical protein, similar to cell shape determinant mreD
NP_646416.1	hypothetical protein, similar to cell shape determinant mreC; in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall
NP_646420.1	hypothetical protein, similar to transporter PAB2175 from Pyrococcus abyssi
NP_646421.1	DNA repair protein RadC homolog; Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase
NP_646422.1	hypothetical protein, similar to type IV prepilin peptidase
NP_646424.1	valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain
NP_646428.1	Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway
NP_646429.1	catalyzes the formation of porphobilinogen from 5-aminolevulinate
NP_646431.1	transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis
NP_646433.1	catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins
NP_646434.1	binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential
NP_646435.1	binds and unfolds substrates as part of the ClpXP protease
NP_646436.1	Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer
NP_646439.1	binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit
NP_646441.1	IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits
NP_646443.1	catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr)
NP_646444.1	Primosomal protein that may act to load helicase DnaC during DNA replication
NP_646448.1	catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis
NP_646449.1	hypothetical protein, similar to formamidopyrimidine-DNA glycosylase
NP_646455.1	Converts isocitrate to alpha ketoglutarate
NP_646456.1	catalyzes the formation of citrate from acetyl-CoA and oxaloacetate
NP_646459.1	catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis
NP_646460.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein
NP_646461.1	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits
NP_646462.1	malate dehydrogenase homolog
NP_646468.1	Xaa-Pro dipeptidase homolog
NP_646471.1	acetate kinase homolog; AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA
NP_646473.1	Probable thiol peroxidase; antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein
NP_646475.1	Probable thiamine biosynthesis protein thiI; Required for the synthesis of the thiazole moiety
NP_646476.1	hypothetical protein, similar to iron-sulfur cofactor synthesis protein nifZ
NP_646477.1	Septation ring formation regulator ezrA; acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation
NP_646479.1	primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination
NP_646480.1	hypothetical protein, similar to glycerophosphoryl diester phosphodiesterase
NP_646482.1	hypothetical protein, similar to soluble hydrogenase 42 kD subunit
NP_646483.1	catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate
NP_646486.1	hypothetical protein, similar to acylglycerol-3-phosphate O-acyltransfera homolog
NP_646487.1	hypothetical protein, similar to serine proteinase Do, heat-shock protein htrA
NP_646492.1	catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate
NP_646493.1	Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA
NP_646494.1	acetoin dehydrogenase homolog
NP_646497.1	chorismate mutase homolog; catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NP_646499.1	hypothetical protein, similar to general stress protein homolog
NP_646500.1	Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis
NP_646501.1	DNA translocase stage III sporulation prot homolog
NP_646502.1	phenylalanyl-tRNA synthetase (beta subunit) homolog
NP_646504.1	thioredoxin homolog
NP_646505.1	endo-1,4-beta-glucanase homolog
NP_646508.1	tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine
NP_646511.1	Xaa-His dipeptidase homolog; divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases
NP_646513.1	hypothetical protein, similar to 16S pseudouridylate synthase
NP_646514.1	spore cortex protein homolog
NP_646516.1	hypothetical protein, similar to FmtB protein
NP_646518.1	leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase
NP_646519.1	multidrug resistance protein homolog
NP_646523.1	lysophospholipase homolog
NP_646524.1	proline dehydrohenase homolog
NP_646525.1	RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not
NP_646527.1	catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine
NP_646530.1	arsenical resistance operon repressor homolog
NP_646531.1	aesenical pump membrane protein homolog
NP_646538.1	hypothetical protein, similar to transaldolase; similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity
NP_646540.1	may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling
NP_646543.1	plant metabolite dehydrogenase homolog
NP_646545.1	methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase
NP_646546.1	PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP
NP_646554.1	hypothetical protein, similar to latent nuclear antigen [Kaposi's sarcoma-associated herpesvirus]
NP_646568.1	type I restriction enzyme EcoR124II M PROTEIN homolog
NP_646574.1	hypothetical protein, similar to Ear protein [Genomic island nu Sa beta2]
NP_646575.1	[Genomic island nu Sa beta2]
NP_646576.1	[Genomic island nu Sa beta2]
NP_646577.1	[Genomic island nu Sa beta2]
NP_646578.1	[Genomic island nu Sa beta2]
NP_646579.1	[Genomic island nu Sa beta2]
NP_646580.1	[Genomic island nu Sa beta2]
NP_646581.1	[Genomic island nu Sa beta2]
NP_646582.1	[Genomic island nu Sa beta2]
NP_646583.1	[Genomic island nu Sa beta2]
NP_646589.1	catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX
NP_646590.1	ferrochelatase homolog; protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic
NP_646591.1	catalyzes the formation of coproporphyrinogen from uroporphyrinogen III
NP_646593.1	hypothetical protein, similar to ABC transporter ecsB
NP_646594.1	ABC transporter ecsA homolog
NP_646599.1	peptidyl-prolyl cis/trans isomerase homolog
NP_646600.1	catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates
NP_646606.1	two-component response regulator homolog
NP_646607.1	two-component sensor histidine kinase homolog
NP_646609.1	class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle
NP_646616.1	hypothetical protein, similar to glutamine-binding periplasmic protein
NP_646617.1	hypothetical protein, similar to regulatory protein
NP_646618.1	transcription regulator Fur family homolog
NP_646619.1	hypothetical protein, similar to D-3-phosphoglycerate dehydrogenase
NP_646621.1	converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate
NP_646623.1	ABC transporter (ATP-binding protein) homolog
NP_646625.1	hypothetical protein, similar to A/G-specific adenine glycosylase
NP_646627.1	hypothetical protein, similar to teichoic acid transport protein tagG
NP_646628.1	hypothetical protein, similar to teichoic acid translocation ATP-binding protein tagH
NP_646630.1	binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities
NP_646631.1	Monofunctional glycosyltransferase; monofunctional; catalyzes the elongation of glycan strands in cell wall biosynthesis
NP_646638.1	Low molecular weight protein-tyrosine-phosphatase ptpA
NP_646640.1	hypothetical protein, similar to transporter
NP_646645.1	catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn
NP_646649.1	hypothetical protein, similar to cobyric acid synthase CobQ
NP_646650.1	hypothetical protein, similar to UDP-N-acetylmuramyl tripeptide synthetase homolo
NP_646651.1	Ferritin
NP_646652.1	hypothetical protein, similar to DNA polymerase III, alpha chain PolC type
NP_646653.1	involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function
NP_646655.1	RNA methyltransferase homolog
NP_646656.1	similar to YegS from E. coli
NP_646657.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
NP_646658.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA
NP_646659.1	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain
NP_646662.1	polydeoxyribonucleotide syntase
NP_646664.1	PcrB-like protein; GGGP synthase; member of prenyltransferases that transfer isoprenoid groups to nonisoprenoid acceptors; functions in form GGGP from glycerol-1-phosphate (G-1-P) and geranylgeranyl pyrophosphate (GGPP); important in lipid metabolism and especially important as the ether linkages in archaea are different than those in bacteria; GGGP synthase lies at the branch point for membrane lipid biosynthesis; cytosolic; T acidophilum protein acts as a homodimer while M thermoautotrophicum protein has been reported to function as a pentamer
NP_646666.1	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide
NP_646670.1	catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers
NP_646671.1	nicotinate phosphoribosyltransferase homolog; catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate
NP_646672.1	nitric-oxide synthase homolog
NP_646673.1	hypothetical protein, similar to chorismate mutase/prephenate dehydratase
NP_646674.1	Sodium-dependent dicarboxylate transporter sdcS (Na(+)/dicarboxylate symporter).
NP_646676.1	pyrazinamidase/nicotinamidase homolog
NP_646677.1	catalyzes the hydrolysis of pyrophosphate to phosphate
NP_646689.1	hypothetical protein, similar to ABC transporter, ATP-binding protein
NP_646691.1	hypothetical protein, similar to ABC transporter, ATP-binding protein
NP_646692.1	hypothetical protein, similar to transcription regulator, GntR family
NP_646695.1	hypothetical protein, similar to aspartate transaminase protein
NP_646704.1	holin homolog [Bacteriophage phi Sa 3mw]
NP_646758.1	Uncharacterized leukocidin-like protein 1 precursor.
NP_646759.1	Uncharacterized leukocidin-like protein 2 precursor.
NP_646760.1	Probable succinyl-diaminopimelate desuccinylase; dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica
NP_646763.1	hypothetical protein, similar to Na+-transporting ATP synthase
NP_646764.1	hypothetical protein, similar to acetyltransferase [Genomic island nu Sa 4mw]
NP_646766.1	hypothetical protein, similar to bacteriophage terminase small subunit [Genomic island nu Sa 4mw]
NP_646768.1	truncated hypothetical protein, similar to integrase [Genomic island nu Sa 4mw]
NP_646769.1	truncated hypothetical protein, similar to integrase [Genomic island nu Sa 4mw]
NP_646770.1	60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth
NP_646771.1	10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring
NP_646773.1	hypothetical protein, similar to SdrH
NP_646776.1	Lyses erythrocytes and other mammalian cells
NP_646781.1	hypothetical protein, similar to fructokinase
NP_646787.1	modulates transcription in response to the NADH/NAD(+) redox state
NP_646789.1	hypothetical protein, similar to DNA mismatch repair protein MutS
NP_646790.1	Probable O-sialoglycoprotein endopeptidase; in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity
NP_646791.1	hypothetical protein, similar to ribosomal-protein-alanine N-acetyltransfer
NP_646792.1	hypothetical protein, similar to glycoprotein endopeptidase
NP_646794.1	catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis
NP_646796.1	hypothetical protein, similar to acetolactate synthase small subunit; with IlvI catalyzes the formation of 2-acetolactate from pyruvate, this subunit subunit is required for full activity and valine sensitivity; also known as acetolactate synthase small
NP_646797.1	catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis
NP_646798.1	catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis
NP_646799.1	catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis
NP_646800.1	dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate
NP_646801.1	catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D
NP_646802.1	catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic
NP_646805.1	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase
NP_646806.1	binds to sigma-B preventing the formation of an RNA polymerase holoenzyme
NP_646812.1	Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids
NP_646816.1	one of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; the C subunit may be involved in assembly of the KDP complex
NP_646817.1	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
NP_646818.1	catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions
NP_646821.1	Probable DEAD-box ATP-dependent RNA helicase MW2004.
NP_646823.1	D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli
NP_646824.1	hypothetical protein, similar to rod shape determining protein RodA
NP_646828.1	Cardiolipin synthetase
NP_646831.1	Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate
NP_646832.1	catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP
NP_646833.1	catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine
NP_646834.1	Putative thiaminase-2
NP_646837.1	hypothetical protein, similar to SceD precursor
NP_646838.1	hypothetical protein, similar to single strand DNA binding protein
NP_646840.1	in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP
NP_646841.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
NP_646843.1	part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane
NP_646844.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit
NP_646845.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit
NP_646846.1	produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit
NP_646847.1	Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex
NP_646848.1	produces ATP from ADP in the presence of a proton gradient across the membrane; subunit B is part of the membrane proton channel
NP_646849.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0
NP_646850.1	Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0
NP_646853.1	Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate
NP_646854.1	catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate
NP_646856.1	Low molecular weight protein-tyrosine-phosphatase ptpB
NP_646858.1	hypothetical protein, similar to protoporphyrinogen oxidase
NP_646859.1	recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2
NP_646860.1	catalyzes the formation of thymidine 5'-phosphate from thymidine
NP_646861.1	RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome
NP_646862.1	An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes
NP_646863.1	Putative aldehyde dehydrogenase MW2046
NP_646865.1	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active
NP_646866.1	catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; induced by anaerobic conditions in Bacillus subtilis
NP_646868.1	CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer
NP_646869.1	participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NP_646870.1	hypothetical protein, similar to spermine/spermidine acetyltransferase blt
NP_646871.1	catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type II pantothenate kinases are not regulated by feedback inhibition by coenzyme A
NP_646875.1	catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2
NP_646877.2	Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway
NP_646878.1	catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate
NP_646879.1	catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate
NP_646884.1	hypothetical protein, similar to mannnose-6 phospate isomelase pmi
NP_646887.1	cation-efflux system membrane protein homolog
NP_646890.1	hypothetical protein, similar to transposase for IS232
NP_646892.1	hypothetical protein, similar to transposase for IS232
NP_646893.1	hypothetical protein, similar to transposase for IS232
NP_646896.1	hypothetical protein, similar to ABC transporter (ATP-binding protein)
NP_646897.1	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NP_646900.1	hypothetical protein, similar to transcription antiterminator BglG family
NP_646905.1	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NP_646909.1	hypothetical protein, similar to ATP-binding Mrp-like protein
NP_646910.1	hypothetical protein, similar to multidrug resistance protein
NP_646912.1	hypothetical protein, similar to multidrug transporter
NP_646913.1	hypothetical protein, similar to hemolysin III
NP_646914.1	Probable uridylyltransferase MW2097
NP_646918.1	hypothetical protein, similar to ferrichrome ABC transporter (permease)
NP_646919.1	hypothetical protein, similar to ferrichrome ABC transporter (permease)
NP_646920.1	hypothetical protein, similar toferrichrome ABC transporter (binding prote)
NP_646923.1	hypothetical protein, similar to transporter
NP_646928.1	glycine betaine transporter opuD homolog
NP_646929.1	Zinc-type alcohol dehydrogenase-like protein MW2112.
NP_646930.1	hypothetical protein, similar to quinone oxidoreductase
NP_646932.1	catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside
NP_646935.1	catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources
NP_646936.1	catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP
NP_646937.1	catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate
NP_646938.1	catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization
NP_646940.1	Modulates the activities of several enzymes which are inactive in their acetylated form
NP_646942.1	hypothetical protein, similar to YnaE
NP_646944.1	hypothetical protein, similar to oxidoreductase, aldo/keto reductase family
NP_646945.1	hypothetical protein, similar to transcription regulator MerR family
NP_646947.1	hypothetical protein, similar to MHC class II analog
NP_646948.1	hypothetical protein, similar to alpha-acetolactate decarboxylase
NP_646949.1	catalyzes the formation of 2-acetolactate from pyruvate in stationary phase
NP_646953.1	forms a direct contact with the tRNA during translation
NP_646954.1	in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit
NP_646955.1	mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability
NP_646957.1	Cobalt import ATP-binding protein cbiO 1; with CbiNQ forms the ABC transporter for cobalt import; Staphylococcus has two adjacent copies of this gene
NP_646958.1	Cobalt import ATP-binding protein cbiO 2; with CbiNQ forms the ABC transporter for cobalt import; Staphylococcus has two adjacent copies of this gene
NP_646959.1	is a component of the macrolide binding site in the peptidyl transferase center
NP_646960.1	catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme
NP_646961.1	located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3
NP_646962.1	located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA
NP_646963.1	smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif
NP_646964.1	stimulates the activities of the other two initiation factors, IF-2 and IF-3
NP_646965.1	essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP
NP_646966.1	forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
NP_646967.1	late assembly protein
NP_646968.1	L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7
NP_646969.1	located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance
NP_646970.1	binds 5S rRNA along with protein L5 and L25
NP_646971.1	ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance
NP_646972.1	binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NP_646973.1	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif
NP_646974.1	part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13
NP_646975.1	assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel
NP_646976.1	binds to the 23S rRNA between the centers for peptidyl transferase and GTPase
NP_646977.1	primary binding protein; helps mediate assembly; involved in translation fidelity
NP_646978.1	one of the stabilizing components for the large ribosomal subunit
NP_646979.1	located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e
NP_646980.1	forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation
NP_646981.1	binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center
NP_646982.1	protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NP_646983.1	one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation
NP_646984.1	binds third domain of 23S rRNA and protein L29; part of exit tunnel
NP_646985.1	L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA
NP_646986.1	binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin
NP_646987.1	NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex
NP_646990.1	decatenates replicating daughter chromosomes
NP_646992.1	glucose uptake protein homolog
NP_646996.1	hypothetical protein, similar to acriflavin resistance protein
NP_647000.1	Uncharacterized HTH-type transcriptional regulator MW2183.
NP_647004.1	in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis
NP_647009.1	MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis
NP_647015.1	FdhD protein homolog; involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth
NP_647017.1	hypothetical protein, similar to biotin biosynthesis protein
NP_647018.1	hypothetical protein, similar to inosine-adenosine-guanosine-nucleoside hydrolase; IAG-nucleoside hydrolase
NP_647019.1	hypothetical protein, similar to ferrichrome ABC transporter fhuD precursor
NP_647020.1	hypothetical protein, similar to butyryl-CoA dehydrogenase
NP_647022.1	hypothetical protein, similar to urea transporter
NP_647023.1	UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter
NP_647024.1	ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Staphylococcus saprophyticus plays a role in bladder invasiveness and may induce the formation of kidney and bladder stones due to the alkalization of urine
NP_647025.1	ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits
NP_647026.1	involved in the assembly of the urease metallocenter; possible nickel donor
NP_647030.1	staphylococcal accessory regulator A homolog
NP_647033.1	hypothetical protein, similar to transcription regulator
NP_647034.1	secretory antigen precursor SsaA homolog
NP_647036.1	hypothetical protein, similar to Na+/H+ antiporter
NP_647037.1	hypothetical protein, similar to D-octopine dehydrogenase
NP_647039.1	hypothetical protein, similar to secretory antigen precursor SsaA
NP_647041.1	Putative 2-hydroxyacid dehydrogenase MW2224; Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor
NP_647042.1	hypothetical protein, similar to monooxygenase
NP_647043.1	hypothetical protein, similar to autolysin E
NP_647046.1	formate dehydrogenase homolog
NP_647047.1	hypothetical protein, similar to lyt divergon expression attenuator LytR
NP_647048.1	hypothetical protein, similar to suppressor protein suhB
NP_647051.1	hypothetical protein, similar to protein of pXO2-46
NP_647053.1	hypothetical protein, similar to transcription regulator, RpiR family
NP_647054.1	hypothetical protein, similar to transport protein
NP_647058.1	hypothetical protein, similar to phosphoglycolate phosphatase
NP_647059.1	hypothetical protein, similar to sodium-dependent transporter
NP_647062.1	hypothetical protein, similar to transcriptional regulator
NP_647064.1	hypothetical protein, similar to Na+/H+ antiporter, putative
NP_647066.1	hypothetical protein, similar to dehydrogenase
NP_647067.1	hypothetical protein, similar to amino acid amidohydrolase
NP_647068.1	catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway
NP_647069.1	catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism
NP_647070.1	hypothetical protein, similar to transcription regulator LysR family
NP_647071.1	Formimidoylglutamase; catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate
NP_647073.1	Ribose-5-phosphate isomerase A; catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway
NP_647075.1	hypothetical protein, similar to aldose 1-epimerase
NP_647078.1	hypothetical protein, similar to ABC transporter
NP_647082.1	Putative 3-methyladenine DNA glycosylase
NP_647083.1	hypothetical protein, similar to sodium/glutamate symporter
NP_647084.1	catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate
NP_647085.1	hypothetical protein, similar to divalent cation transport
NP_647088.1	hypothetical protein, similar to esterase
NP_647090.1	hypothetical protein, similar to multidrug resistance protein
NP_647092.1	hypothetical protein, similar to transcriptional regulator (TetR/AcrR family)
NP_647096.1	hypothetical protein, similar to membrane protein
NP_647097.1	Putative hemin import ATP-binding protein hrtA
NP_647099.1	hypothetical protein, similar to two component response regulator
NP_647100.1	hypothetical protein, similar to two component histidine kinase sensor
NP_647103.1	Probable malate:quinone oxidoreductase 1; malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate
NP_647104.1	L-lactate permease lctP homolog
NP_647106.1	Uncharacterized lipoprotein MW2289 precursor.
NP_647107.1	hypothetical protein, similar to transcription repressor of sporulation, septation and degradation paiA
NP_647109.1	hypothetical protein, similar to export protein
NP_647111.1	hypothetical protein, similar to thioredoxin reductase
NP_647113.1	hypothetical protein, similar to phage infection protein precursor
NP_647114.1	hypothetical protein, similar to transcriptional regulator tetR-family
NP_647115.1	hypothetical protein, similar to cationic transporter
NP_647118.1	hypothetical protein, similar to transcription regulatory protein
NP_647119.1	hypothetical protein, similar to general stress protein 26
NP_647123.1	HTH-type transcriptional regulator sarZ (Staphylococcal accessory regulator Z).
NP_647124.1	hypothetical protein, similar to small heat shock protein
NP_647129.1	hypothetical protein, similar to transcriptional regulator
NP_647130.1	hypothetical protein, similar to response regulators of two-component regulatory
NP_647131.1	hypothetical protein, similar to two component sensor histidine kinase
NP_647134.1	hypothetical protein, similar to nitrate reductase delta chain
NP_647140.1	hypothetical protein, similar to NirR
NP_647142.1	hypothetical protein, similar to NirC
NP_647145.1	hypothetical protein, similar to Zn-binding lipoprotein adcA
NP_647151.1	hypothetical protein, similar to ABC transporter, ATP binding subunit
NP_647152.1	hypothetical protein, similar to ABC transporter, permease protein
NP_647153.1	hypothetical protein, similar to ABC transporter, periplasmic amino acid-binding protein
NP_647154.1	hypothetical protein, similar to multidrug resistance protein
NP_647156.1	phosphoglycerate mutase, pgm homolog; 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate
NP_647162.1	hypothetical protein, similar to BioX protein
NP_647163.1	catalyzes the formation of pimeloyl-CoA from pimelate and coenzyme A
NP_647164.1	hypothetical protein, similar to 8-amino-7-oxononanoate synthase
NP_647165.1	catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine
NP_647168.1	hypothetical protein, similar to ABC transporter, ATP-binding protein
NP_647169.1	hypothetical protein, similar to lipoprotein inner membrane ABC-transporter
NP_647175.1	hypothetical protein, similar to bicyclomycin resistance protein TcaB
NP_647176.1	hypothetical protein, similar to transcriptional activator
NP_647179.1	amino acid ABC transporter homolog
NP_647180.1	hypothetical protein, similar to NA(+)/H(+) exchanger
NP_647182.1	Protein flp (FmtA-like protein).
NP_647183.1	hypothetical protein, similar to glucose epimerase
NP_647184.1	hypothetical protein, similar to 2-dehydropantoate 2-reductase; ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis
NP_647185.1	hypothetical protein, similar to integral membrane efflux protein
NP_647191.1	hypothetical protein, similar to amino acid transporter
NP_647192.1	hypothetical protein, similar to para-nitrobenzyl esterase chain A
NP_647193.1	hypothetical protein, similar to chloramphenicol resistance protein
NP_647195.1	hypothetical protein, similar to ABC transporter (ATP-binding protein)
NP_647196.1	hypothetical protein, similar to endo-1,4-beta-glucanase
NP_647200.1	hypothetical protein, similar to glutamate synthase (ferredoxin)
NP_647203.1	hypothetical protein, similar to antibiotic resistance protein
NP_647211.1	hypothetical protein, similar to diaminopimelate epimerase
NP_647213.1	hypothetical protein, similar to glucose 1-dehydrogenase
NP_647214.1	hypothetical protein, similar to efflux pump
NP_647220.1	Uncharacterized oxidoreductase MW2403
NP_647227.1	hypothetical protein, similar to mutator protein mutT
NP_647228.1	Phosphoglucomutase
NP_647233.1	Putative surface protein MW2416 precursor.
NP_647234.1	staphylococcal accessory regulator A homolog
NP_647235.1	staphylococcal accessory regulator A homolog
NP_647237.1	fibronectin-binding protein homolog
NP_647238.1	fibronectin-binding protein homolog
NP_647243.1	hypothetical protein, similar to transcriptional regulator, MerR family
NP_647244.1	hypothetical protein, similar to GTP-pyrophosphokinase
NP_647248.1	hypothetical protein, similar to glucarate transporter
NP_647249.1	hypothetical protein, similar to alkaline phosphatase
NP_647250.1	hypothetical protein, similar to ABC transporter
NP_647251.1	hypothetical protein, similar to membrane spanning protein
NP_647257.1	hypothetical protein, similar to transcription regulator MarR family
NP_647260.1	Putative NAD(P)H nitroreductase MW2443
NP_647261.1	catalyzes the formation of pyruvate from lactate
NP_647263.1	hypothetical protein, similar to ABC transporter (ATP-binding protein)
NP_647266.1	hypothetical protein, similar to N-acetyltransferase
NP_647268.1	hypothetical protein, similar to L-serine dehydratase
NP_647269.1	hypothetical protein, similar to beta-subunit of L-serine dehydratas
NP_647270.1	hypothetical protein, similar to regulatory protein pfoR
NP_647274.1	hypothetical protein, similar to thioredoxin
NP_647277.1	hypothetical protein, similar to pyruvate oxidase; catalyzes the formation of acetyl phosphate from pyruvate
NP_647280.1	hypothetical protein, similar to transcription regulator
NP_647282.1	hypothetical protein, similar to secretory antigen precursor SsaA
NP_647288.1	ferrous iron transport protein B homolog
NP_647290.1	hypothetical protein, similar to antibiotic transport-associated protein
NP_647291.1	hypothetical protein, similar to transcriptional regulator tetR-family
NP_647292.1	catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate
NP_647293.1	Putative acetyltransferase MW2476
NP_647296.1	hypothetical protein, similar to mercuric ion-binding protein
NP_647297.1	hypothetical protein, similar to D-specific D-2-hydroxyacid dehydrogenase ddh homolog; catalyzes the formation of pyruvate from lactate
NP_647298.1	hypothetical protein, similar to aspartate aminotransferase
NP_647302.1	4,4'-diaponeurosporene oxidase
NP_647304.1	Staphylococcal secretory antigen ssaA1 precursor.
NP_647305.1	O-acetyltransferase oatA
NP_647308.1	hypothetical protein, similar to regulatory protein (pfoS/R)
NP_647309.1	hypothetical protein, similar to transcriptional regulator (TetR/AcrR family)
NP_647315.1	HTH-type transcriptional regulator MW2498.
NP_647316.1	hypothetical protein, similar to short chain oxidoreductase
NP_647319.1	hypothetical protein, similar to cobalamin synthesis related protein CobW
NP_647320.1	hypothetical protein, similar to ferrous iron transporter protein B
NP_647326.1	hypothetical protein, similar to dihydroorotate dehydrogenase; catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors
NP_647330.1	hypothetical protein, similar to transcriptional regulator tetR-family
NP_647333.1	Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5)
NP_647334.1	catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine
NP_647335.1	catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate
NP_647336.1	hypothetical protein, similar to 2-dehydropantoate 2-reductase; catalyzes the formation of 2-dehydropantoate from (R)-pantoate
NP_647337.1	hypothetical protein, similar to alpha-acetolactate decarboxylase
NP_647339.1	hypothetical protein, similar to amino acid transporter
NP_647340.1	hypothetical protein, similar to pyridoxal-phosphate dependent aminotransferase; catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate
NP_647342.1	fructose-bisphosphate aldolase homolog; catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis
NP_647343.1	malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate
NP_647348.1	catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine
NP_647353.1	hypothetical protein, similar to anaerobic ribonucleotide reductase activator protein
NP_647354.1	Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates
NP_647355.1	hypothetical protein, similar to magnesium citrate secondary transporter
NP_647356.1	hypothetical protein, similar to uroporphyrin-III C-methyltransferase; catalyzes the formation of siroheme from precorrin-2
NP_647358.1	hypothetical protein, similar to glutathione peroxidase
NP_647359.1	hypothetical protein, similar to ABC transporter (permease)
NP_647360.1	hypothetical protein, similar to ABC transporter (ATP-binding protein)
NP_647361.1	hypothetical protein, similar to two-component sensor histidine kinase
NP_647362.1	hypothetical protein, similar to two-component response regulator
NP_647366.1	hypothetical protein, similar to transcriptional regulator
NP_647367.1	hypothetical protein, similar to tributyrin esterase
NP_647369.1	hypothetical protein, similar to transcription regulator Crp/Fnr family protein
NP_647370.2	catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP
NP_647372.1	catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway
NP_647373.1	catalyzes the degradation of arginine to citruline and ammonia
NP_647374.1	hypothetical protein, similar to arginine repressor
NP_647378.1	hypothetical protein, similar to transcription antiterminator BglG family
NP_647379.1	fructose phosphotransferase system enzyme fruA homolog
NP_647381.1	hypothetical protein, similar to phage infection protein
NP_647382.1	hypothetical protein, similar to autolysin precursor
NP_647383.1	hypothetical protein, similar to N-Carbamoylsarcosine Amidohydrolase
NP_647386.1	hypothetical protein, similar to lipopolysaccharide biosynthesis protein
NP_647387.1	preprotein translocase secA homolog; functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins
NP_647391.1	hypothetical protein, similar to preprotein translocase secY; forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase
NP_647392.1	Serine-rich adhesin for platelets precursor (Staphylococcus aureus surface protein A).
NP_647397.1	hypothetical protein, similar to peptide methionine sulfoxide reductase; this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; a fusion protein of this enzyme with MsrB provides protection against oxidative stress in Neisseria gonorrhoeae
NP_647403.1	predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein
NP_647408.1	catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis
NP_647409.1	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase
NP_647410.1	catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-hosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide
NP_647411.1	with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide
NP_647412.1	catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis
NP_647413.1	hypothetical protein, similar to histidinol-phosphate transaminase
NP_647414.1	Histidinol dehydrogenase; catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer
NP_647415.1	short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ
NP_647416.1	May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NP_647420.1	Putative ABC transporter ATP-binding protein MW2603
NP_647427.1	catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline
NP_647430.1	2-oxoglutarate/malate translocator homolog
NP_647432.1	hypothetical protein, similar to rarD protein
NP_647434.1	hypothetical protein, similar to high-affinity nickel-transport protein
NP_647435.1	hypothetical protein, similar to N-hydroxyarylamine O-acetyltransferase
NP_647437.1	hypothetical protein, similar to ABC transporter
NP_647438.1	hypothetical protein, similar to ABC transporter (permease)
NP_647444.1	hypothetical protein, similar to DNA-binding protein Spo0J-like homolog
NP_647445.1	glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA
NP_647446.1	GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs
NP_647447.1	in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE
NP_647448.1	protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates
NP_647449.1	in Escherichia coli transcription of this gene is enhanced by polyamines